locus-tag	class	description
TIIST44_RS00005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TIIST44_RS00020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TIIST44_RS00025	COG0072	phenylalanine-tRNA ligase activity
TIIST44_RS00025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TIIST44_RS00030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TIIST44_RS00040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TIIST44_RS00045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TIIST44_RS00050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TIIST44_RS00065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TIIST44_RS00070	COG0140	phosphoribosyl-ATP diphosphatase activity
TIIST44_RS00075	COG3201	nicotinamide mononucleotide transporter
TIIST44_RS00090	COG0667	Aldo Keto reductase
TIIST44_RS00095	COG0372	Belongs to the citrate synthase family
TIIST44_RS00100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TIIST44_RS00120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TIIST44_RS00135	COG0792	nuclease activity
TIIST44_RS00145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TIIST44_RS00150	COG0681	Belongs to the peptidase S26 family
TIIST44_RS00155	COG0335	large ribosomal subunit rRNA binding
TIIST44_RS00165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TIIST44_RS00170	COG1053	succinate dehydrogenase
TIIST44_RS00180	COG0336	Belongs to the RNA methyltransferase TrmD family
TIIST44_RS00185	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TIIST44_RS00190	COG1837	Belongs to the UPF0109 family
TIIST44_RS00195	COG0228	four-way junction DNA binding
TIIST44_RS00245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TIIST44_RS00250	COG0571	ribonuclease III activity
TIIST44_RS00255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TIIST44_RS00275	COG0395	ABC-type sugar transport system, permease component
TIIST44_RS00310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TIIST44_RS00330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TIIST44_RS00335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TIIST44_RS00340	COG0028	Belongs to the TPP enzyme family
TIIST44_RS00350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TIIST44_RS00355	COG1185	polyribonucleotide nucleotidyltransferase activity
TIIST44_RS00360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TIIST44_RS00380	COG4175	Glycine betaine
TIIST44_RS00380	COG0517	IMP dehydrogenase activity
TIIST44_RS00385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TIIST44_RS00415	COG3732	PTS system glucitol sorbitol-specific
TIIST44_RS00435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TIIST44_RS00450	COG1131	(ABC) transporter
TIIST44_RS00455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TIIST44_RS00465	COG0779	Required for maturation of 30S ribosomal subunits
TIIST44_RS00475	COG0730	response to heat
TIIST44_RS00485	COG0442	prolyl-tRNA aminoacylation
TIIST44_RS00495	COG0803	Belongs to the bacterial solute-binding protein 9 family
TIIST44_RS00495	COG0803	Belongs to the bacterial solute-binding protein 9 family
TIIST44_RS00505	COG1121	(ABC) transporter
TIIST44_RS00510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TIIST44_RS00515	COG0456	acetyltransferase
TIIST44_RS00520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TIIST44_RS00545	COG0750	zinc metalloprotease
TIIST44_RS00550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TIIST44_RS00565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TIIST44_RS00570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TIIST44_RS00575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TIIST44_RS00585	COG0575	Belongs to the CDS family
TIIST44_RS00590	COG0233	cytoplasmic translational termination
TIIST44_RS00595	COG0528	UMP kinase activity
TIIST44_RS00600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TIIST44_RS00605	COG0052	Belongs to the universal ribosomal protein uS2 family
TIIST44_RS00610	COG4974	Belongs to the 'phage' integrase family
TIIST44_RS00620	COG0242	peptide deformylase activity
TIIST44_RS00645	COG1119	ATPase activity
TIIST44_RS00655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TIIST44_RS00675	COG2226	methyltransferase
TIIST44_RS00685	COG0488	(ABC) transporter
TIIST44_RS00715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TIIST44_RS00720	COG0396	ATPase activity
TIIST44_RS00735	COG0719	Fe-S assembly protein
TIIST44_RS00750	COG1175	transmembrane transport
TIIST44_RS00755	COG3833	ABC-type maltose transport systems, permease component
TIIST44_RS00765	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TIIST44_RS00770	COG1131	(ABC) transporter
TIIST44_RS00780	COG1612	heme a metabolic process
TIIST44_RS00790	COG0109	protoheme IX farnesyltransferase activity
TIIST44_RS00805	COG0363	glucosamine-6-phosphate deaminase activity
TIIST44_RS00820	COG0525	valine-tRNA ligase activity
TIIST44_RS00825	COG0366	Alpha amylase catalytic
TIIST44_RS00825	COG1470	cell adhesion involved in biofilm formation
TIIST44_RS00830	COG0793	Belongs to the peptidase S41A family
TIIST44_RS00830	COG4946	Tricorn protease homolog
TIIST44_RS00835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TIIST44_RS00840	COG0740	serine-type endopeptidase activity
TIIST44_RS00845	COG0740	serine-type endopeptidase activity
TIIST44_RS00855	COG0544	peptidyl-prolyl cis-trans isomerase activity
TIIST44_RS00900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TIIST44_RS00900	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TIIST44_RS00920	COG0698	ribose 5-phosphate isomerase
TIIST44_RS00925	COG4552	Acetyltransferase involved in intracellular survival and related
TIIST44_RS00930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TIIST44_RS00950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TIIST44_RS00955	COG0366	Alpha amylase catalytic
TIIST44_RS00980	COG1695	Transcriptional regulator
TIIST44_RS00995	COG0629	single-stranded DNA binding
TIIST44_RS01025	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
TIIST44_RS01035	COG1113	amino acid transport
TIIST44_RS01040	COG0515	serine threonine protein kinase
TIIST44_RS01045	COG1472	Belongs to the glycosyl hydrolase 3 family
TIIST44_RS01070	COG0587	DNA-directed DNA polymerase activity
TIIST44_RS01090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TIIST44_RS01175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TIIST44_RS01185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
TIIST44_RS01190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TIIST44_RS01195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TIIST44_RS01200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TIIST44_RS01225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TIIST44_RS01255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TIIST44_RS01270	COG2835	tetraacyldisaccharide 4'-kinase activity
TIIST44_RS01305	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
TIIST44_RS01305	COG0662	Cupin 2, conserved barrel domain protein
TIIST44_RS01325	COG1316	TRANSCRIPTIONal
TIIST44_RS01350	COG3340	Belongs to the peptidase S51 family
TIIST44_RS01365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TIIST44_RS01375	COG0424	maF-like protein
TIIST44_RS01385	COG4221	oxidoreductase activity
TIIST44_RS01390	COG0351	phosphomethylpyrimidine kinase
TIIST44_RS01405	COG0598	Magnesium transport protein CorA
TIIST44_RS01415	COG4770	biotin carboxylase activity
TIIST44_RS01435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TIIST44_RS01450	COG0477	Major facilitator Superfamily
TIIST44_RS01460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TIIST44_RS01465	COG0328	RNA-DNA hybrid ribonuclease activity
TIIST44_RS01475	COG1079	Belongs to the binding-protein-dependent transport system permease family
TIIST44_RS01480	COG4603	Belongs to the binding-protein-dependent transport system permease family
TIIST44_RS01485	COG3845	ABC transporter
TIIST44_RS01490	COG1744	ABC transporter substrate-binding protein PnrA-like
TIIST44_RS01500	COG1253	flavin adenine dinucleotide binding
TIIST44_RS01520	COG0039	L-malate dehydrogenase activity
TIIST44_RS01525	COG1012	belongs to the aldehyde dehydrogenase family
TIIST44_RS01535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TIIST44_RS01555	COG0138	bifunctional purine biosynthesis protein purh
TIIST44_RS01565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TIIST44_RS01570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TIIST44_RS01570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TIIST44_RS01580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TIIST44_RS01580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TIIST44_RS01595	COG0045	succinate-CoA ligase (ADP-forming) activity
TIIST44_RS01605	COG1464	Belongs to the NlpA lipoprotein family
TIIST44_RS01610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TIIST44_RS01615	COG2011	ABC-type metal ion transport system permease component
TIIST44_RS01620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TIIST44_RS01635	COG0519	Catalyzes the synthesis of GMP from XMP
TIIST44_RS01635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TIIST44_RS01645	COG1045	serine acetyltransferase
TIIST44_RS01650	COG1605	Chorismate mutase
TIIST44_RS01650	COG0287	Prephenate dehydrogenase
TIIST44_RS01655	COG0516	GMP reductase activity
TIIST44_RS01670	COG1115	amino acid carrier protein
TIIST44_RS01680	COG0459	protein refolding
TIIST44_RS01685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TIIST44_RS01710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TIIST44_RS01715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TIIST44_RS01730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TIIST44_RS01735	COG0456	acetyltransferase
TIIST44_RS01745	COG0802	atpase or kinase
TIIST44_RS01755	COG0513	Belongs to the DEAD box helicase family
TIIST44_RS01770	COG0438	transferase activity, transferring glycosyl groups
TIIST44_RS01770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TIIST44_RS01780	COG0736	holo-[acyl-carrier-protein] synthase activity
TIIST44_RS01785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TIIST44_RS01800	COG1072	(Pantothenic acid kinase))
TIIST44_RS01810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TIIST44_RS01815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TIIST44_RS01820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TIIST44_RS01840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TIIST44_RS01845	COG0101	tRNA pseudouridine synthase activity
TIIST44_RS01860	COG3845	ABC transporter
TIIST44_RS01870	COG1028	Short-chain dehydrogenase reductase Sdr
TIIST44_RS01910	COG2271	Major facilitator Superfamily
TIIST44_RS01915	COG0438	transferase activity, transferring glycosyl groups
TIIST44_RS01920	COG0203	ribosomal protein L17
TIIST44_RS01925	COG0202	RNA polymerase activity
TIIST44_RS01930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TIIST44_RS01935	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TIIST44_RS01940	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TIIST44_RS01945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TIIST44_RS01950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TIIST44_RS01960	COG0563	adenylate kinase activity
TIIST44_RS01980	COG0584	glycerophosphoryl diester phosphodiesterase
TIIST44_RS02010	COG0200	Binds to the 23S rRNA
TIIST44_RS02015	COG1841	ribosomal large subunit assembly
TIIST44_RS02020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TIIST44_RS02025	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TIIST44_RS02030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TIIST44_RS02035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TIIST44_RS02040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TIIST44_RS02045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TIIST44_RS02050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TIIST44_RS02055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TIIST44_RS02060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TIIST44_RS02065	COG0255	Belongs to the universal ribosomal protein uL29 family
TIIST44_RS02070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TIIST44_RS02075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TIIST44_RS02080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TIIST44_RS02085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TIIST44_RS02090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TIIST44_RS02095	COG0089	rRNA binding
TIIST44_RS02100	COG0088	Forms part of the polypeptide exit tunnel
TIIST44_RS02105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TIIST44_RS02110	COG0051	transcription antitermination factor activity, RNA binding
TIIST44_RS02120	COG0156	8-amino-7-oxononanoate synthase activity
TIIST44_RS02130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TIIST44_RS02135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TIIST44_RS02140	COG0737	Belongs to the 5'-nucleotidase family
TIIST44_RS02150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TIIST44_RS02165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TIIST44_RS02170	COG0049	tRNA binding
TIIST44_RS02175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TIIST44_RS02195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TIIST44_RS02200	COG0085	RNA polymerase activity
TIIST44_RS02205	COG0222	ribosome binding
TIIST44_RS02210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TIIST44_RS02215	COG0081	regulation of translation
TIIST44_RS02220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TIIST44_RS02225	COG0250	Participates in transcription elongation, termination and antitermination
TIIST44_RS02230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TIIST44_RS02240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TIIST44_RS02245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TIIST44_RS02255	COG2030	dehydratase
TIIST44_RS02260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TIIST44_RS02280	COG0708	Exodeoxyribonuclease III
TIIST44_RS02285	COG1024	Enoyl-CoA hydratase
TIIST44_RS02295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TIIST44_RS02300	COG0649	NAD binding
TIIST44_RS02305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TIIST44_RS02315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TIIST44_RS02315	COG0674	pyruvate-flavodoxin oxidoreductase activity
TIIST44_RS02320	COG1013	pyruvate-flavodoxin oxidoreductase activity
TIIST44_RS02335	COG3590	peptidase
TIIST44_RS02355	COG1126	abc transporter atp-binding protein
TIIST44_RS02380	COG2301	Belongs to the HpcH HpaI aldolase family
TIIST44_RS02390	COG0142	geranyltranstransferase activity
TIIST44_RS02395	COG1007	ATP synthesis coupled electron transport
TIIST44_RS02410	COG0713	ATP synthesis coupled electron transport
TIIST44_RS02420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TIIST44_RS02425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TIIST44_RS02430	COG1034	ATP synthesis coupled electron transport
TIIST44_RS02435	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TIIST44_RS02445	COG0649	NAD binding
TIIST44_RS02450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TIIST44_RS02455	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TIIST44_RS02465	COG0644	oxidoreductase
TIIST44_RS02490	COG2226	methyltransferase
TIIST44_RS02500	COG1132	(ABC) transporter
TIIST44_RS02510	COG1136	(ABC) transporter
TIIST44_RS02520	COG2814	Major facilitator Superfamily
TIIST44_RS02525	COG2376	Dihydroxyacetone kinase
TIIST44_RS02530	COG1461	Dihydroxyacetone kinase
TIIST44_RS02535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TIIST44_RS02535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TIIST44_RS02535	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
TIIST44_RS02545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TIIST44_RS02555	COG0039	L-malate dehydrogenase activity
TIIST44_RS02585	COG1175	transmembrane transport
TIIST44_RS02590	COG0395	ABC-type sugar transport system, permease component
TIIST44_RS02640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TIIST44_RS02655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TIIST44_RS02680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TIIST44_RS02700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TIIST44_RS02730	COG0047	phosphoribosylformylglycinamidine synthase activity
TIIST44_RS02735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TIIST44_RS02750	COG0583	DNA-binding transcription factor activity
TIIST44_RS02755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TIIST44_RS02760	COG0151	Belongs to the GarS family
TIIST44_RS02765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TIIST44_RS02775	COG2186	Transcriptional regulator
TIIST44_RS02780	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
TIIST44_RS02785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TIIST44_RS02805	COG1217	gtp-binding protein TYPA
TIIST44_RS02840	COG0840	transmembrane signaling receptor activity
TIIST44_RS02850	COG0191	fructose-bisphosphate aldolase activity
TIIST44_RS02865	COG0586	Pfam SNARE associated Golgi protein
TIIST44_RS02890	COG2814	Major facilitator Superfamily
TIIST44_RS02895	COG0542	response to heat
TIIST44_RS02910	COG3588	fructose-bisphosphate aldolase
TIIST44_RS02925	COG4585	Histidine kinase
TIIST44_RS02930	COG2197	response regulator
TIIST44_RS02935	COG4591	ABC-type transport system involved in lipoprotein release permease component
TIIST44_RS02935	COG1136	(ABC) transporter
TIIST44_RS02940	COG0577	efflux transmembrane transporter activity
TIIST44_RS02940	COG1136	(ABC) transporter
TIIST44_RS02945	COG1051	belongs to the nudix hydrolase family
TIIST44_RS02950	COG1113	amino acid transport
TIIST44_RS02955	COG0569	domain protein
TIIST44_RS02955	COG2985	domain, Protein
TIIST44_RS02970	COG0789	Transcriptional regulator
TIIST44_RS02975	COG0484	heat shock protein binding
TIIST44_RS02980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TIIST44_RS03000	COG0745	RESPONSE REGULATOR receiver
TIIST44_RS03005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TIIST44_RS03020	COG0574	Belongs to the PEP-utilizing enzyme family
TIIST44_RS03020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TIIST44_RS03025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
TIIST44_RS03035	COG3830	Belongs to the UPF0237 family
TIIST44_RS03035	COG0560	Phosphoserine phosphatase
TIIST44_RS03040	COG0676	glucose-6-phosphate 1-epimerase activity
TIIST44_RS03050	COG0154	amidase activity
TIIST44_RS03095	COG0662	Cupin 2, conserved barrel domain protein
TIIST44_RS03110	COG1132	(ABC) transporter
TIIST44_RS03110	COG2375	cellular response to nickel ion
TIIST44_RS03140	COG1131	(ABC) transporter
TIIST44_RS03150	COG0508	dehydrogenase complex catalyzes the overall conversion of
TIIST44_RS03155	COG0022	dehydrogenase e1 component
TIIST44_RS03165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TIIST44_RS03170	COG0535	radical SAM domain protein
TIIST44_RS03190	COG1132	(ABC) transporter
TIIST44_RS03205	COG2378	regulation of single-species biofilm formation
TIIST44_RS03215	COG2801	Transposase and inactivated derivatives
TIIST44_RS03215	COG3415	Transposase
TIIST44_RS03260	COG2205	protein histidine kinase activity
TIIST44_RS03275	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TIIST44_RS03290	COG1902	pentaerythritol trinitrate reductase activity
TIIST44_RS03300	COG0477	Major facilitator Superfamily
TIIST44_RS03305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TIIST44_RS03305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TIIST44_RS03310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TIIST44_RS03340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TIIST44_RS03345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TIIST44_RS03355	COG0018	arginyl-trna synthetase
TIIST44_RS03360	COG0656	L-ascorbic acid biosynthetic process
TIIST44_RS03370	COG0166	Belongs to the GPI family
TIIST44_RS03385	COG0783	Belongs to the Dps family
TIIST44_RS03390	COG4581	dead DEAH box helicase
TIIST44_RS03395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TIIST44_RS03405	COG1881	PFAM PEBP family protein
TIIST44_RS03445	COG0701	Predicted permease
TIIST44_RS03465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TIIST44_RS03470	COG1408	metallophosphoesterase
TIIST44_RS03480	COG0693	protein deglycase activity
TIIST44_RS03490	COG0601	transmembrane transport
TIIST44_RS03495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TIIST44_RS03510	COG0254	rRNA binding
TIIST44_RS03515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TIIST44_RS03520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TIIST44_RS03525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TIIST44_RS03540	COG1472	Belongs to the glycosyl hydrolase 3 family
TIIST44_RS03545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TIIST44_RS03550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TIIST44_RS03560	COG1228	amidohydrolase
TIIST44_RS03565	COG2986	histidine ammonia-lyase
TIIST44_RS03585	COG1857	crispr-associated protein
TIIST44_RS03600	COG1518	maintenance of DNA repeat elements
TIIST44_RS03625	COG5265	(ABC) transporter
TIIST44_RS03640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TIIST44_RS03655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TIIST44_RS03675	COG3263	regulation of cellular component size
TIIST44_RS03705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TIIST44_RS03710	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
TIIST44_RS03725	COG3158	transport of potassium into the cell
TIIST44_RS03730	COG0505	Belongs to the CarA family
TIIST44_RS03755	COG1609	Transcriptional regulator
TIIST44_RS03760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TIIST44_RS03795	COG1063	alcohol dehydrogenase
TIIST44_RS03800	COG0137	argininosuccinate synthase activity
TIIST44_RS03820	COG0561	phosphatase activity
TIIST44_RS03840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TIIST44_RS03845	COG0644	oxidoreductase
TIIST44_RS03880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TIIST44_RS03895	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
TIIST44_RS03905	COG1968	undecaprenyl-diphosphatase activity
TIIST44_RS03910	COG1528	Iron-storage protein
TIIST44_RS03925	COG0359	binds to the 23S rRNA
TIIST44_RS03930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TIIST44_RS03935	COG0629	single-stranded DNA binding
TIIST44_RS03940	COG0360	Binds together with S18 to 16S ribosomal RNA
TIIST44_RS03955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TIIST44_RS03955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS03955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS03960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS03960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TIIST44_RS03960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS03970	COG1022	Amp-dependent synthetase and ligase
TIIST44_RS03975	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TIIST44_RS03995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TIIST44_RS04005	COG2608	mercury ion transmembrane transporter activity
TIIST44_RS04010	COG1937	Protein conserved in bacteria
TIIST44_RS04015	COG0305	Participates in initiation and elongation during chromosome replication
TIIST44_RS04020	COG3321	synthase
TIIST44_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
TIIST44_RS04020	COG0604	alcohol dehydrogenase
TIIST44_RS04030	COG2094	Belongs to the DNA glycosylase MPG family
TIIST44_RS04045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TIIST44_RS04050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TIIST44_RS04065	COG1113	amino acid transport
TIIST44_RS04085	COG0534	Mate efflux family protein
TIIST44_RS04100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TIIST44_RS04125	COG0205	6-phosphofructokinase activity
TIIST44_RS04130	COG0686	Belongs to the AlaDH PNT family
TIIST44_RS04135	COG1113	amino acid transport
TIIST44_RS04150	COG1376	ErfK ybiS ycfS ynhG family protein
TIIST44_RS04155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TIIST44_RS04165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TIIST44_RS04170	COG0686	Belongs to the AlaDH PNT family
TIIST44_RS04205	COG5012	cobalamin binding
TIIST44_RS04215	COG3457	Alanine racemase
TIIST44_RS04220	COG1113	amino acid transport
TIIST44_RS04225	COG1113	amino acid transport
TIIST44_RS04230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TIIST44_RS04235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TIIST44_RS04240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TIIST44_RS04260	COG0114	fumarate hydratase activity
TIIST44_RS04265	COG0395	ABC-type sugar transport system, permease component
TIIST44_RS04270	COG1175	transmembrane transport
TIIST44_RS04290	COG0668	transmembrane transport
TIIST44_RS04295	COG1929	Belongs to the glycerate kinase type-1 family
TIIST44_RS04305	COG0617	tRNA 3'-terminal CCA addition
TIIST44_RS04315	COG0515	serine threonine protein kinase
TIIST44_RS04320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TIIST44_RS04325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TIIST44_RS04335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TIIST44_RS04340	COG3534	alpha-L-arabinofuranosidase
TIIST44_RS04345	COG0492	ferredoxin-NADP+ reductase activity
TIIST44_RS04360	COG0657	acetylesterase activity
TIIST44_RS04370	COG3118	belongs to the thioredoxin family
TIIST44_RS04375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TIIST44_RS04380	COG2390	Transcriptional regulator
TIIST44_RS04395	COG0371	Dehydrogenase
TIIST44_RS04400	COG1069	ribulokinase activity
TIIST44_RS04415	COG0698	ribose 5-phosphate isomerase
TIIST44_RS04430	COG0235	Class ii aldolase
TIIST44_RS04440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TIIST44_RS04450	COG1349	DNA-binding transcription factor activity
TIIST44_RS04455	COG1312	Catalyzes the dehydration of D-mannonate
TIIST44_RS04460	COG0246	Mannitol dehydrogenase
TIIST44_RS04465	COG1904	glucuronate isomerase
TIIST44_RS04470	COG1609	Transcriptional regulator
TIIST44_RS04475	COG2211	Major facilitator Superfamily
TIIST44_RS04485	COG3250	beta-galactosidase activity
TIIST44_RS04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TIIST44_RS04510	COG1181	Belongs to the D-alanine--D-alanine ligase family
TIIST44_RS04515	COG1181	Belongs to the D-alanine--D-alanine ligase family
TIIST44_RS04525	COG2814	Major facilitator Superfamily
TIIST44_RS04530	COG1475	DNA binding
TIIST44_RS04545	COG0357	Ribosomal RNA small subunit methyltransferase G
TIIST44_RS04575	COG0706	membrane insertase activity
TIIST44_RS04580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TIIST44_RS04590	COG0594	ribonuclease P activity
TIIST44_RS04595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TIIST44_RS04600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TIIST44_RS04605	COG0592	DNA-directed DNA polymerase activity
TIIST44_RS04615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TIIST44_RS04625	COG1132	(ABC) transporter
TIIST44_RS04630	COG1482	cell wall glycoprotein biosynthetic process
TIIST44_RS04635	COG0187	DNA topoisomerase II activity
TIIST44_RS04640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TIIST44_RS04650	COG0039	L-malate dehydrogenase activity
TIIST44_RS04655	COG1609	Transcriptional regulator
TIIST44_RS04660	COG1129	ABC transporter
TIIST44_RS04665	COG1172	Belongs to the binding-protein-dependent transport system permease family
TIIST44_RS04675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TIIST44_RS04680	COG1869	D-ribose catabolic process
TIIST44_RS04710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TIIST44_RS04720	COG3775	system Galactitol-specific IIC component
TIIST44_RS04725	COG3414	Phosphotransferase system galactitol-specific IIB component
TIIST44_RS04730	COG1063	alcohol dehydrogenase
TIIST44_RS04765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TIIST44_RS04770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TIIST44_RS04840	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TIIST44_RS04860	COG4591	ABC-type transport system involved in lipoprotein release permease component
TIIST44_RS04865	COG0577	efflux transmembrane transporter activity
TIIST44_RS04865	COG1136	(ABC) transporter
TIIST44_RS04870	COG2197	response regulator
TIIST44_RS04880	COG0395	ABC-type sugar transport system, permease component
TIIST44_RS04885	COG1175	transmembrane transport
TIIST44_RS04895	COG1349	DNA-binding transcription factor activity
TIIST44_RS04900	COG1486	melibiose metabolic process
TIIST44_RS04925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TIIST44_RS04935	COG4585	Histidine kinase
TIIST44_RS04940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TIIST44_RS04945	COG1309	transcriptional regulator
TIIST44_RS04950	COG2409	Drug exporters of the RND superfamily
TIIST44_RS04970	COG1136	(ABC) transporter
TIIST44_RS04985	COG0058	SHG alpha-glucan phosphorylase activity
TIIST44_RS05000	COG5426	von Willebrand factor, type A
TIIST44_RS05015	COG1175	transmembrane transport
TIIST44_RS05020	COG0395	ABC-type sugar transport system, permease component
TIIST44_RS05030	COG1609	Transcriptional regulator
TIIST44_RS05055	COG0205	6-phosphofructokinase activity
TIIST44_RS05075	COG1027	Aspartate ammonia-lyase
TIIST44_RS05080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
TIIST44_RS05095	COG1132	(ABC) transporter
TIIST44_RS05100	COG1132	(ABC) transporter
TIIST44_RS05105	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TIIST44_RS05120	COG0641	radical SAM
TIIST44_RS05125	COG1120	ATPase activity
TIIST44_RS05140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TIIST44_RS05155	COG4716	Myosin-crossreactive antigen
TIIST44_RS05160	COG0351	phosphomethylpyrimidine kinase
TIIST44_RS05160	COG0352	thiamine-phosphate diphosphorylase activity
TIIST44_RS05160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
TIIST44_RS05165	COG0352	thiamine-phosphate diphosphorylase activity
TIIST44_RS05185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
TIIST44_RS05195	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
TIIST44_RS05255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TIIST44_RS05315	COG3104	oligopeptide transport
TIIST44_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
TIIST44_RS05335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS05335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS05340	COG1105	Belongs to the carbohydrate kinase PfkB family
TIIST44_RS05350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TIIST44_RS05360	COG0438	transferase activity, transferring glycosyl groups
TIIST44_RS05370	COG0297	glycogen (starch) synthase activity
TIIST44_RS05385	COG1252	NADH dehydrogenase
TIIST44_RS05395	COG1643	Atp-dependent helicase
TIIST44_RS05400	COG4721	ABC-type cobalt transport system, permease component
TIIST44_RS05405	COG1129	ABC transporter
TIIST44_RS05420	COG0167	dihydroorotate dehydrogenase activity
TIIST44_RS05425	COG1013	pyruvate-flavodoxin oxidoreductase activity
TIIST44_RS05425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TIIST44_RS05425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TIIST44_RS05425	COG0674	pyruvate-flavodoxin oxidoreductase activity
TIIST44_RS05440	COG2186	Transcriptional regulator
TIIST44_RS05445	COG1620	l-lactate permease
TIIST44_RS05450	COG0247	lactate metabolic process
TIIST44_RS05455	COG1139	Iron-sulfur cluster binding protein
TIIST44_RS05460	COG1556	Lactate utilization protein
TIIST44_RS05465	COG1122	ATPase activity
TIIST44_RS05480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
TIIST44_RS05485	COG4988	ABC transporter
TIIST44_RS05490	COG1294	oxidase, subunit
TIIST44_RS05495	COG1271	oxidase subunit
TIIST44_RS05515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TIIST44_RS05530	COG0515	serine threonine protein kinase
TIIST44_RS05530	COG2815	serine threonine protein kinase
TIIST44_RS05535	COG0768	penicillin binding
TIIST44_RS05550	COG1716	ATPase activity
TIIST44_RS05670	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TIIST44_RS05675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TIIST44_RS05685	COG1136	(ABC) transporter
TIIST44_RS05685	COG0577	efflux transmembrane transporter activity
TIIST44_RS05700	COG0561	phosphatase activity
TIIST44_RS05705	COG0561	phosphatase activity
TIIST44_RS05710	COG3842	ATPase activity
TIIST44_RS05720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TIIST44_RS05725	COG3681	Belongs to the UPF0597 family
TIIST44_RS05730	COG0814	amino acid
TIIST44_RS05740	COG0673	inositol 2-dehydrogenase activity
TIIST44_RS05775	COG0494	nUDIX hydrolase
TIIST44_RS05785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TIIST44_RS05835	COG1111	helicase
TIIST44_RS05835	COG1205	dead DEAH box helicase
TIIST44_RS05840	COG2890	protein-(glutamine-N5) methyltransferase activity
TIIST44_RS05850	COG1754	DNA topoisomerase type I activity
TIIST44_RS05850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TIIST44_RS05860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TIIST44_RS05865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TIIST44_RS05875	COG1774	PSP1 C-terminal conserved region
TIIST44_RS05900	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
TIIST44_RS05920	COG3458	cephalosporin-C deacetylase activity
TIIST44_RS05930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TIIST44_RS05940	COG0037	tRNA processing
TIIST44_RS05955	COG0302	gtp cyclohydrolase
TIIST44_RS05990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TIIST44_RS05995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TIIST44_RS06015	COG0649	NAD binding
TIIST44_RS06045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TIIST44_RS06050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TIIST44_RS06055	COG1984	allophanate hydrolase subunit 2
TIIST44_RS06065	COG1090	epimerase
TIIST44_RS06070	COG0705	Rhomboid family
TIIST44_RS06080	COG2197	response regulator
TIIST44_RS06085	COG4585	Histidine kinase
TIIST44_RS06095	COG3711	transcriptional antiterminator
TIIST44_RS06100	COG2190	(PTS) system
TIIST44_RS06100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TIIST44_RS06100	COG1263	PTS System
TIIST44_RS06105	COG2190	(PTS) system
TIIST44_RS06105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TIIST44_RS06105	COG1263	PTS System
TIIST44_RS06110	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
TIIST44_RS06120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TIIST44_RS06130	COG1349	DNA-binding transcription factor activity
TIIST44_RS06135	COG1194	a g-specific adenine glycosylase
TIIST44_RS06140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TIIST44_RS06145	COG0113	porphobilinogen synthase activity
TIIST44_RS06155	COG0181	hydroxymethylbilane synthase activity
TIIST44_RS06165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TIIST44_RS06170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TIIST44_RS06175	COG3253	May function as heme-dependent peroxidase
TIIST44_RS06175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TIIST44_RS06185	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
TIIST44_RS06190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TIIST44_RS06205	COG1082	Xylose isomerase domain protein TIM barrel
TIIST44_RS06210	COG0506	proline dehydrogenase activity
TIIST44_RS06225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TIIST44_RS06245	COG0406	alpha-ribazole phosphatase activity
TIIST44_RS06250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TIIST44_RS06255	COG0785	Cytochrome C biogenesis protein
TIIST44_RS06260	COG1333	cytochrome c biogenesis protein
TIIST44_RS06265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TIIST44_RS06275	COG4221	oxidoreductase activity
TIIST44_RS06285	COG1136	(ABC) transporter
TIIST44_RS06310	COG1120	ATPase activity
TIIST44_RS06315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TIIST44_RS06325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TIIST44_RS06345	COG0406	alpha-ribazole phosphatase activity
TIIST44_RS06345	COG0494	nUDIX hydrolase
TIIST44_RS06350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TIIST44_RS06355	COG0745	RESPONSE REGULATOR receiver
TIIST44_RS06365	COG1490	D-aminoacyl-tRNA deacylase activity
TIIST44_RS06370	COG3485	protocatechuate 3,4-dioxygenase
TIIST44_RS06380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TIIST44_RS06390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TIIST44_RS06395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TIIST44_RS06400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TIIST44_RS06405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TIIST44_RS06420	COG1329	Transcriptional regulator
TIIST44_RS06430	COG0745	RESPONSE REGULATOR receiver
TIIST44_RS06455	COG0588	phosphoglycerate mutase activity
TIIST44_RS06470	COG0252	asparaginase activity
TIIST44_RS06475	COG1113	amino acid transport
TIIST44_RS06480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TIIST44_RS06485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TIIST44_RS06490	COG0800	Aldolase
TIIST44_RS06515	COG0673	inositol 2-dehydrogenase activity
TIIST44_RS06520	COG0673	inositol 2-dehydrogenase activity
TIIST44_RS06530	COG5492	domain, Protein
TIIST44_RS06545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TIIST44_RS06550	COG0215	cysteine-tRNA ligase activity
TIIST44_RS06565	COG0626	cystathionine gamma-synthase activity
TIIST44_RS06575	COG1302	Protein conserved in bacteria
TIIST44_RS06600	COG1595	DNA-templated transcription, initiation
TIIST44_RS06615	COG3842	ATPase activity
TIIST44_RS06625	COG1760	l-serine dehydratase
TIIST44_RS06640	COG1175	transmembrane transport
TIIST44_RS06645	COG0395	ABC-type sugar transport system, permease component
TIIST44_RS06650	COG1063	alcohol dehydrogenase
TIIST44_RS06665	COG1174	glycine betaine transport
TIIST44_RS06690	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TIIST44_RS06695	COG2130	NADP-dependent
TIIST44_RS06700	COG1131	(ABC) transporter
TIIST44_RS06710	COG4585	Histidine kinase
TIIST44_RS06715	COG4585	Histidine kinase
TIIST44_RS06720	COG2197	response regulator
TIIST44_RS06725	COG0406	alpha-ribazole phosphatase activity
TIIST44_RS06730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TIIST44_RS06735	COG1492	cobalamin metabolic process
TIIST44_RS06755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TIIST44_RS06755	COG1648	precorrin-2 dehydrogenase activity
TIIST44_RS06770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TIIST44_RS06775	COG1120	ATPase activity
TIIST44_RS06795	COG0310	cobalt ion transport
TIIST44_RS06830	COG1797	cobyrinic acid a,c-diamide synthase activity
TIIST44_RS06840	COG2099	Precorrin-6x reductase
TIIST44_RS06845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TIIST44_RS06880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TIIST44_RS06880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS06880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TIIST44_RS06900	COG1854	S-ribosylhomocysteine lyase activity
TIIST44_RS06920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TIIST44_RS06940	COG3718	enzyme involved in inositol metabolism
TIIST44_RS06945	COG3962	Belongs to the TPP enzyme family
TIIST44_RS06960	COG1609	Transcriptional regulator
TIIST44_RS06970	COG1082	Xylose isomerase domain protein TIM barrel
TIIST44_RS06975	COG1082	Xylose isomerase domain protein TIM barrel
TIIST44_RS06985	COG2814	Major facilitator Superfamily
TIIST44_RS07000	COG1082	Xylose isomerase domain protein TIM barrel
TIIST44_RS07005	COG0673	inositol 2-dehydrogenase activity
TIIST44_RS07025	COG1061	Type III restriction enzyme res subunit
TIIST44_RS07040	COG0363	glucosamine-6-phosphate deaminase activity
TIIST44_RS07045	COG1278	Cold shock
TIIST44_RS07060	COG2252	PERMEase
TIIST44_RS07075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TIIST44_RS07100	COG2814	Major facilitator Superfamily
TIIST44_RS07120	COG1970	mechanosensitive ion channel activity
TIIST44_RS07135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TIIST44_RS07140	COG0303	'Molybdopterin
TIIST44_RS07165	COG0315	cyclic pyranopterin monophosphate synthase activity
TIIST44_RS07185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TIIST44_RS07220	COG1140	nitrate reductase beta subunit
TIIST44_RS07235	COG0746	molybdenum cofactor guanylyltransferase activity
TIIST44_RS07240	COG0521	Mo-molybdopterin cofactor biosynthetic process
TIIST44_RS07240	COG0315	cyclic pyranopterin monophosphate synthase activity
TIIST44_RS07255	COG0437	4 iron, 4 sulfur cluster binding
TIIST44_RS07260	COG0243	molybdopterin cofactor binding
TIIST44_RS07270	COG2022	thiamine diphosphate biosynthetic process
TIIST44_RS07280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TIIST44_RS07280	COG2022	thiamine diphosphate biosynthetic process
TIIST44_RS07285	COG0598	Magnesium transport protein CorA
TIIST44_RS07290	COG2233	PERMEase
TIIST44_RS07305	COG0084	hydrolase, TatD family'
TIIST44_RS07310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TIIST44_RS07315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TIIST44_RS07320	COG1846	Transcriptional regulator
TIIST44_RS07335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TIIST44_RS07340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TIIST44_RS07360	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TIIST44_RS07365	COG0193	aminoacyl-tRNA hydrolase activity
TIIST44_RS07395	COG0148	phosphopyruvate hydratase activity
TIIST44_RS07450	COG0647	UMP catabolic process
TIIST44_RS07455	COG1268	BioY protein
TIIST44_RS07460	COG1122	ATPase activity
TIIST44_RS07480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TIIST44_RS07485	COG0497	DNA recombination
TIIST44_RS07500	COG0504	CTP synthase activity
TIIST44_RS07505	COG0494	nUDIX hydrolase
TIIST44_RS07530	COG0545	Peptidyl-prolyl cis-trans isomerase
TIIST44_RS07535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TIIST44_RS07555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TIIST44_RS07560	COG0805	protein transport
TIIST44_RS07565	COG4581	dead DEAH box helicase
TIIST44_RS07570	COG0107	imidazoleglycerol-phosphate synthase activity
TIIST44_RS07575	COG0537	adenosine 5'-monophosphoramidase activity
TIIST44_RS07585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TIIST44_RS07595	COG0473	3-isopropylmalate dehydrogenase activity
TIIST44_RS07600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TIIST44_RS07615	COG1266	CAAX protease self-immunity
TIIST44_RS07630	COG1414	Transcriptional regulator
TIIST44_RS07635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TIIST44_RS07645	COG0066	3-isopropylmalate dehydratase activity
TIIST44_RS07655	COG1181	Belongs to the D-alanine--D-alanine ligase family
TIIST44_RS07675	COG1674	ftsk spoiiie
TIIST44_RS07690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TIIST44_RS07695	COG2884	Cell division ATP-binding protein ftsE
TIIST44_RS07700	COG2177	Part of the ABC transporter FtsEX involved in
TIIST44_RS07705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TIIST44_RS07710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TIIST44_RS07715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TIIST44_RS07725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TIIST44_RS07730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TIIST44_RS07735	COG0165	Argininosuccinate lyase
TIIST44_RS07755	COG1131	(ABC) transporter
TIIST44_RS07820	COG1678	Uncharacterized ACR, COG1678
TIIST44_RS07825	COG0745	RESPONSE REGULATOR receiver
TIIST44_RS07830	COG5000	phosphorelay sensor kinase activity
TIIST44_RS07830	COG5002	protein histidine kinase activity
TIIST44_RS07835	COG5401	PFAM Sporulation and spore germination
TIIST44_RS07845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TIIST44_RS07850	COG0653	protein targeting
TIIST44_RS07870	COG2902	Dehydrogenase
TIIST44_RS07875	COG0613	PHP domain protein
TIIST44_RS07880	COG0180	Tryptophanyl-tRNA synthetase
TIIST44_RS07885	COG1113	amino acid transport
TIIST44_RS07890	COG0513	Belongs to the DEAD box helicase family
TIIST44_RS07925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TIIST44_RS07930	COG1074	ATP-dependent DNA helicase activity
TIIST44_RS07935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
TIIST44_RS07960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TIIST44_RS08115	COG0747	negative chemotaxis
TIIST44_RS08120	COG0601	transmembrane transport
TIIST44_RS08125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TIIST44_RS08130	COG0444	Belongs to the ABC transporter superfamily
TIIST44_RS08140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TIIST44_RS08145	COG0483	inositol monophosphate 1-phosphatase activity
TIIST44_RS08155	COG1162	GTPase activity
TIIST44_RS08160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TIIST44_RS08170	COG1595	DNA-templated transcription, initiation
TIIST44_RS08200	COG0567	Dehydrogenase, E1 component
TIIST44_RS08200	COG0508	dehydrogenase complex catalyzes the overall conversion of
TIIST44_RS08220	COG0460	homoserine dehydrogenase
TIIST44_RS08225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TIIST44_RS08230	COG0083	homoserine kinase activity
TIIST44_RS08240	COG0254	rRNA binding
TIIST44_RS08245	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TIIST44_RS08250	COG2890	protein-(glutamine-N5) methyltransferase activity
TIIST44_RS08260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TIIST44_RS08275	COG0356	it plays a direct role in the translocation of protons across the membrane
TIIST44_RS08280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TIIST44_RS08285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TIIST44_RS08290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TIIST44_RS08295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TIIST44_RS08300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TIIST44_RS08305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TIIST44_RS08310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TIIST44_RS08330	COG1846	Transcriptional regulator
TIIST44_RS08335	COG2814	Major facilitator Superfamily
TIIST44_RS08340	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TIIST44_RS08360	COG1230	cation diffusion facilitator family transporter
TIIST44_RS08390	COG1216	Glycosyl transferase, family 2
TIIST44_RS08400	COG1522	sequence-specific DNA binding
TIIST44_RS08415	COG0427	acetyl-CoA hydrolase
TIIST44_RS08430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TIIST44_RS08435	COG0738	Major facilitator superfamily
TIIST44_RS08445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TIIST44_RS08455	COG1160	GTP binding
TIIST44_RS08460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TIIST44_RS08465	COG0287	Prephenate dehydrogenase
TIIST44_RS08470	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TIIST44_RS08475	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TIIST44_RS08485	COG1129	ABC transporter
TIIST44_RS08490	COG1511	domain protein
TIIST44_RS08515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TIIST44_RS08535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TIIST44_RS08545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TIIST44_RS08555	COG1758	RNA polymerase activity
TIIST44_RS08560	COG0194	GDP metabolic process
TIIST44_RS08570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TIIST44_RS08575	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TIIST44_RS08580	COG2326	polyphosphate kinase activity
TIIST44_RS08595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TIIST44_RS08600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TIIST44_RS08605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TIIST44_RS08610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TIIST44_RS08615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TIIST44_RS08620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TIIST44_RS08625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TIIST44_RS08640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TIIST44_RS08670	COG0124	histidyl-tRNA synthetase
TIIST44_RS08675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TIIST44_RS08680	COG1196	nuclear chromosome segregation
TIIST44_RS08685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TIIST44_RS08695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TIIST44_RS08700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TIIST44_RS08705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TIIST44_RS08715	COG2255	four-way junction helicase activity
TIIST44_RS08720	COG0632	four-way junction helicase activity
TIIST44_RS08725	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TIIST44_RS08730	COG0217	transcriptional regulatory protein
TIIST44_RS08735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TIIST44_RS08740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TIIST44_RS08745	COG0131	Imidazoleglycerol-phosphate dehydratase
TIIST44_RS08750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TIIST44_RS08755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TIIST44_RS08770	COG1447	Phosphotransferase system cellobiose-specific component IIA
TIIST44_RS08785	COG2723	6-phospho-beta-galactosidase activity
TIIST44_RS08795	COG2971	BadF BadG BcrA BcrD
TIIST44_RS08810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TIIST44_RS08815	COG1737	Transcriptional regulator
TIIST44_RS08825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TIIST44_RS08840	COG0069	glutamate synthase activity
TIIST44_RS08840	COG0067	glutamate synthase
TIIST44_RS08840	COG0070	glutamate synthase
TIIST44_RS08845	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TIIST44_RS08850	COG0159	tryptophan synthase activity
TIIST44_RS08855	COG0133	tryptophan synthase activity
TIIST44_RS08860	COG0134	indole-3-glycerol-phosphate synthase activity
TIIST44_RS08875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TIIST44_RS08880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TIIST44_RS08890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TIIST44_RS08895	COG0154	amidase activity
TIIST44_RS08900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TIIST44_RS08925	COG0482	sulfurtransferase activity
TIIST44_RS08940	COG0366	Alpha amylase catalytic
TIIST44_RS08955	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TIIST44_RS08975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TIIST44_RS08985	COG0033	Phosphoglucomutase
TIIST44_RS09030	COG1739	Uncharacterized protein family UPF0029
TIIST44_RS09040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TIIST44_RS09045	COG0009	L-threonylcarbamoyladenylate synthase
TIIST44_RS09055	COG0205	6-phosphofructokinase activity
TIIST44_RS09065	COG1295	ribonuclease BN
TIIST44_RS09085	COG1716	ATPase activity
TIIST44_RS09090	COG0509	glycine decarboxylation via glycine cleavage system
TIIST44_RS09115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TIIST44_RS09125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TIIST44_RS09130	COG2197	response regulator
TIIST44_RS09140	COG1064	alcohol dehydrogenase
TIIST44_RS09165	COG2326	polyphosphate kinase activity
TIIST44_RS09170	COG1113	amino acid transport
TIIST44_RS09180	COG2964	Protein conserved in bacteria
TIIST44_RS09190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TIIST44_RS09205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TIIST44_RS09210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TIIST44_RS09220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TIIST44_RS09225	COG0531	amino acid
TIIST44_RS09230	COG0569	domain protein
TIIST44_RS09250	COG0756	dUTP diphosphatase activity
TIIST44_RS09275	COG1435	thymidine kinase activity
TIIST44_RS09295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TIIST44_RS09305	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
TIIST44_RS09310	COG0187	DNA topoisomerase II activity
TIIST44_RS09325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TIIST44_RS09325	COG0493	'glutamate synthase
TIIST44_RS09350	COG1309	transcriptional regulator
TIIST44_RS09355	COG3250	beta-galactosidase activity
TIIST44_RS09360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TIIST44_RS09370	COG1946	Acyl-CoA thioesterase
TIIST44_RS09375	COG1643	Atp-dependent helicase
TIIST44_RS09390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TIIST44_RS09395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TIIST44_RS09405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TIIST44_RS09415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TIIST44_RS09420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TIIST44_RS09425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TIIST44_RS09435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TIIST44_RS09440	COG1288	antiporter activity
TIIST44_RS09445	COG2017	converts alpha-aldose to the beta-anomer
TIIST44_RS09450	COG1418	mRNA catabolic process
TIIST44_RS09455	COG2137	regulation of response to DNA damage stimulus
TIIST44_RS09475	COG1396	sequence-specific DNA binding
TIIST44_RS09480	COG1058	Belongs to the CinA family
TIIST44_RS09480	COG1546	Belongs to the CinA family
TIIST44_RS09490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TIIST44_RS09505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TIIST44_RS09510	COG0284	orotidine-5'-phosphate decarboxylase activity
TIIST44_RS09515	COG0167	dihydroorotate dehydrogenase activity
TIIST44_RS09520	COG0543	2 iron, 2 sulfur cluster binding
TIIST44_RS09525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TIIST44_RS09530	COG0505	Belongs to the CarA family
TIIST44_RS09540	COG0540	Belongs to the ATCase OTCase family
TIIST44_RS09545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TIIST44_RS09550	COG0667	Aldo Keto reductase
TIIST44_RS09555	COG1335	isochorismatase
TIIST44_RS09560	COG1472	Belongs to the glycosyl hydrolase 3 family
TIIST44_RS09580	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
TIIST44_RS09590	COG2814	Major facilitator Superfamily
TIIST44_RS09600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TIIST44_RS09610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TIIST44_RS09615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TIIST44_RS09630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TIIST44_RS09650	COG0714	Associated with various cellular activities
TIIST44_RS09660	COG0561	phosphatase activity
TIIST44_RS09680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TIIST44_RS09685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TIIST44_RS09690	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TIIST44_RS09695	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TIIST44_RS09700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TIIST44_RS09720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TIIST44_RS09725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TIIST44_RS09745	COG0358	DNA primase activity
TIIST44_RS09765	COG0778	Nitroreductase
TIIST44_RS09775	COG1053	succinate dehydrogenase
TIIST44_RS09785	COG0423	glycine-tRNA ligase activity
TIIST44_RS09795	COG2197	response regulator
TIIST44_RS09810	COG1381	Involved in DNA repair and RecF pathway recombination
TIIST44_RS09820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TIIST44_RS09825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TIIST44_RS09830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TIIST44_RS09835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TIIST44_RS09845	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TIIST44_RS09880	COG1668	transmembrane transport
TIIST44_RS09890	COG4152	abc transporter atp-binding protein
TIIST44_RS09895	COG2197	response regulator
TIIST44_RS09900	COG4585	Histidine kinase
TIIST44_RS09905	COG0343	queuine tRNA-ribosyltransferase activity
TIIST44_RS09915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TIIST44_RS09920	COG0514	ATP-dependent DNA helicase (RecQ)
TIIST44_RS09930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
TIIST44_RS09930	COG2213	PTS system mannitol-specific
TIIST44_RS09935	COG1063	alcohol dehydrogenase
TIIST44_RS09945	COG0484	heat shock protein binding
TIIST44_RS09950	COG1420	regulation of RNA biosynthetic process
TIIST44_RS09955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TIIST44_RS09960	COG0483	inositol monophosphate 1-phosphatase activity
TIIST44_RS09975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TIIST44_RS09980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TIIST44_RS09990	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TIIST44_RS10000	COG1169	isochorismate synthase
TIIST44_RS10005	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TIIST44_RS10010	COG4948	Mandelate Racemase Muconate Lactonizing
TIIST44_RS10015	COG0481	GTPase activity
TIIST44_RS10025	COG0268	Binds directly to 16S ribosomal RNA
TIIST44_RS10045	COG1555	photosystem II stabilization
TIIST44_RS10045	COG1596	polysaccharide export
TIIST44_RS10050	COG0495	leucyl-tRNA aminoacylation
TIIST44_RS10075	COG0281	malic enzyme
TIIST44_RS10080	COG0039	L-malate dehydrogenase activity
TIIST44_RS10085	COG0352	thiamine-phosphate diphosphorylase activity
TIIST44_RS10090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TIIST44_RS10095	COG2814	Major facilitator Superfamily
TIIST44_RS10115	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TIIST44_RS10120	COG1735	metal-dependent hydrolase with the TIM-barrel fold
TIIST44_RS10130	COG1309	transcriptional regulator
TIIST44_RS10155	COG0406	alpha-ribazole phosphatase activity
TIIST44_RS10165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TIIST44_RS10175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TIIST44_RS10180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TIIST44_RS10185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TIIST44_RS10190	COG0477	Major facilitator Superfamily
TIIST44_RS10205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TIIST44_RS10210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TIIST44_RS10215	COG1530	ribonuclease E activity
TIIST44_RS10230	COG0105	UTP biosynthetic process
TIIST44_RS10240	COG0285	dihydrofolate synthase activity
TIIST44_RS10250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TIIST44_RS10255	COG0149	triose-phosphate isomerase activity
TIIST44_RS10260	COG0126	phosphoglycerate kinase activity
TIIST44_RS10265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TIIST44_RS10270	COG1481	regulation of sporulation
TIIST44_RS10275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TIIST44_RS10280	COG1660	Displays ATPase and GTPase activities
TIIST44_RS10285	COG0322	excinuclease ABC activity
TIIST44_RS10315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TIIST44_RS10325	COG0556	nucleotide-excision repair
TIIST44_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TIIST44_RS10355	COG1120	ATPase activity
TIIST44_RS10360	COG1429	ligase activity, forming nitrogen-metal bonds
TIIST44_RS10375	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TIIST44_RS10385	COG0237	dephospho-CoA kinase activity
TIIST44_RS10390	COG1132	(ABC) transporter
TIIST44_RS10395	COG4988	ABC transporter
TIIST44_RS10400	COG1120	ATPase activity
TIIST44_RS10405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TIIST44_RS10420	COG0539	negative regulation of cytoplasmic translation
TIIST44_RS10430	COG0277	FAD linked oxidase domain protein
TIIST44_RS10455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TIIST44_RS10460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TIIST44_RS10470	COG0469	pyruvate kinase activity
TIIST44_RS10500	COG1799	cell septum assembly
TIIST44_RS10505	COG1496	oxidoreductase activity
TIIST44_RS10520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TIIST44_RS10525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TIIST44_RS10535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TIIST44_RS10540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TIIST44_RS10545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TIIST44_RS10550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TIIST44_RS10555	COG0768	penicillin binding
TIIST44_RS10565	COG0275	rRNA processing
TIIST44_RS10570	COG2001	Belongs to the MraZ family
TIIST44_RS10575	COG0714	Associated with various cellular activities
TIIST44_RS10595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TIIST44_RS10600	COG0509	glycine decarboxylation via glycine cleavage system
TIIST44_RS10605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TIIST44_RS10605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TIIST44_RS10620	COG3265	gluconokinase activity
TIIST44_RS10645	COG0210	DNA helicase
TIIST44_RS10655	COG0142	geranyltranstransferase activity
TIIST44_RS10670	COG0515	serine threonine protein kinase
TIIST44_RS10670	COG2815	serine threonine protein kinase
TIIST44_RS10680	COG1234	tRNA 3'-trailer cleavage
TIIST44_RS10685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
TIIST44_RS10705	COG1940	carbohydrate kinase activity
TIIST44_RS10710	COG0791	NLP P60 protein
TIIST44_RS10710	COG3103	Sh3 type 3 domain protein
TIIST44_RS10710	COG1388	LysM domain
TIIST44_RS10745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TIIST44_RS10755	COG1845	cytochrome c oxidase, subunit III
TIIST44_RS10760	COG2010	Cytochrome c
TIIST44_RS10765	COG0723	plastoquinol--plastocyanin reductase activity
TIIST44_RS10770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TIIST44_RS10795	COG1136	(ABC) transporter
TIIST44_RS10810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TIIST44_RS10815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TIIST44_RS10850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TIIST44_RS10855	COG0508	dehydrogenase complex catalyzes the overall conversion of
TIIST44_RS10860	COG0321	lipoyl(octanoyl) transferase activity
TIIST44_RS10875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TIIST44_RS10905	COG0488	(ABC) transporter
TIIST44_RS10910	COG5650	phosphatidylinositol metabolic process
TIIST44_RS10925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TIIST44_RS10930	COG4139	cobalamin transport
TIIST44_RS10940	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TIIST44_RS10940	COG3291	Pkd domain containing protein
TIIST44_RS10945	COG2190	(PTS) system
TIIST44_RS10945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TIIST44_RS10945	COG1263	PTS System
TIIST44_RS10950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TIIST44_RS10955	COG1263	PTS System
TIIST44_RS10955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TIIST44_RS10960	COG2188	Transcriptional regulator
TIIST44_RS10965	COG1263	PTS System
TIIST44_RS10975	COG0438	transferase activity, transferring glycosyl groups
TIIST44_RS10985	COG0174	glutamine synthetase
TIIST44_RS11005	COG2966	Psort location CytoplasmicMembrane, score
TIIST44_RS11010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
TIIST44_RS11020	COG0174	glutamine synthetase
TIIST44_RS11040	COG1966	Carbon starvation protein
TIIST44_RS11055	COG1120	ATPase activity
TIIST44_RS11060	COG4139	cobalamin transport
TIIST44_RS11105	COG0006	proline dipeptidase activity
TIIST44_RS11140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TIIST44_RS11145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TIIST44_RS11155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TIIST44_RS11160	COG0297	glycogen (starch) synthase activity
TIIST44_RS11185	COG0477	Major facilitator Superfamily
TIIST44_RS11195	COG1834	amidinotransferase
TIIST44_RS11200	COG2171	N-acyltransferase activity
TIIST44_RS11220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
TIIST44_RS11225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TIIST44_RS11235	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TIIST44_RS11240	COG2376	Dihydroxyacetone kinase
TIIST44_RS11245	COG1063	alcohol dehydrogenase
TIIST44_RS11250	COG1012	belongs to the aldehyde dehydrogenase family
TIIST44_RS11265	COG0803	Belongs to the bacterial solute-binding protein 9 family
TIIST44_RS11275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TIIST44_RS11285	COG1136	(ABC) transporter
TIIST44_RS11300	COG0765	amino acid transport
TIIST44_RS11305	COG1126	abc transporter atp-binding protein
TIIST44_RS11310	COG2501	S4 domain
TIIST44_RS11315	COG1404	Belongs to the peptidase S8 family
TIIST44_RS11350	COG3103	Sh3 type 3 domain protein
TIIST44_RS11350	COG0366	Alpha amylase catalytic
TIIST44_RS11355	COG0833	amino acid
TIIST44_RS11360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TIIST44_RS11365	COG0667	Aldo Keto reductase
TIIST44_RS11370	COG2716	regulation of RNA biosynthetic process
TIIST44_RS11390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TIIST44_RS11395	COG2235	arginine
TIIST44_RS11415	COG1764	response to oxidative stress
TIIST44_RS11420	COG1846	Transcriptional regulator
TIIST44_RS11440	COG0012	GTP binding
TIIST44_RS11445	COG1362	aminopeptidase activity
TIIST44_RS11450	COG1322	Protein conserved in bacteria
TIIST44_RS11455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TIIST44_RS11470	COG1570	exodeoxyribonuclease VII activity
TIIST44_RS11475	COG1722	exodeoxyribonuclease VII activity
TIIST44_RS11485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TIIST44_RS11495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TIIST44_RS11500	COG1331	Highly conserved protein containing a thioredoxin domain
TIIST44_RS11515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TIIST44_RS11530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TIIST44_RS11535	COG0733	neurotransmitter:sodium symporter activity
TIIST44_RS11545	COG4989	oxidoreductase activity
TIIST44_RS11550	COG1297	OPT oligopeptide transporter protein
TIIST44_RS11675	COG0028	Belongs to the TPP enzyme family