locus-tag	class	description
CHL67_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHL67_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHL67_RS00030	COG0426	domain, Protein
CHL67_RS00040	COG0445	tRNA wobble uridine modification
CHL67_RS00060	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL67_RS00065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHL67_RS00070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHL67_RS00080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHL67_RS00085	COG0187	DNA topoisomerase II activity
CHL67_RS00095	COG0792	nuclease activity
CHL67_RS00100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHL67_RS00105	COG1530	ribonuclease E activity
CHL67_RS00110	COG2171	N-acyltransferase activity
CHL67_RS00115	COG0793	Belongs to the peptidase S41A family
CHL67_RS00125	COG0644	oxidoreductase
CHL67_RS00130	COG0423	glycine-tRNA ligase activity
CHL67_RS00140	COG0425	Belongs to the sulfur carrier protein TusA family
CHL67_RS00145	COG1797	cobyrinic acid a,c-diamide synthase activity
CHL67_RS00150	COG2920	part of a sulfur-relay system
CHL67_RS00155	COG2221	Nitrite and sulphite reductase 4Fe-4S
CHL67_RS00160	COG2221	Nitrite and sulphite reductase 4Fe-4S
CHL67_RS00175	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CHL67_RS00180	COG2923	Belongs to the DsrF TusC family
CHL67_RS00210	COG0437	4 iron, 4 sulfur cluster binding
CHL67_RS00220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHL67_RS00220	COG1648	precorrin-2 dehydrogenase activity
CHL67_RS00225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHL67_RS00225	COG1648	precorrin-2 dehydrogenase activity
CHL67_RS00250	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHL67_RS00260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHL67_RS00270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHL67_RS00275	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CHL67_RS00290	COG3360	Dodecin
CHL67_RS00300	COG0243	molybdopterin cofactor binding
CHL67_RS00315	COG2210	Belongs to the sulfur carrier protein TusA family
CHL67_RS00325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHL67_RS00330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHL67_RS00335	COG1116	anion transmembrane transporter activity
CHL67_RS00335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHL67_RS00340	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CHL67_RS00350	COG1151	hydroxylamine reductase activity
CHL67_RS00385	COG0514	ATP-dependent DNA helicase (RecQ)
CHL67_RS00400	COG2111	Na H antiporter
CHL67_RS00400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHL67_RS00405	COG2111	Na H antiporter
CHL67_RS00410	COG1006	Multisubunit Na H antiporter MnhC subunit
CHL67_RS00415	COG0651	ATP synthesis coupled electron transport
CHL67_RS00420	COG1863	multisubunit Na H antiporter MnhE subunit
CHL67_RS00425	COG2212	antiporter activity
CHL67_RS00430	COG1320	monovalent cation:proton antiporter activity
CHL67_RS00445	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHL67_RS00475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHL67_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS00495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHL67_RS00505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHL67_RS00510	COG0750	zinc metalloprotease
CHL67_RS00515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHL67_RS00525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHL67_RS00530	COG0284	orotidine-5'-phosphate decarboxylase activity
CHL67_RS00535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHL67_RS00545	COG1090	epimerase
CHL67_RS00555	COG0724	RNA recognition motif
CHL67_RS00560	COG0004	ammonium transporteR
CHL67_RS00580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHL67_RS00595	COG1214	PFAM Peptidase M22, glycoprotease
CHL67_RS00615	COG0504	CTP synthase activity
CHL67_RS00675	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CHL67_RS00690	COG0842	Transport permease protein
CHL67_RS00700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHL67_RS00735	COG2095	MarC family integral membrane protein
CHL67_RS00760	COG0859	PFAM glycosyl transferase family 9
CHL67_RS00765	COG0708	Exodeoxyribonuclease III
CHL67_RS00770	COG0360	Binds together with S18 to 16S ribosomal RNA
CHL67_RS00775	COG0629	single-stranded DNA binding
CHL67_RS00780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHL67_RS00785	COG0359	binds to the 23S rRNA
CHL67_RS00800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHL67_RS00805	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHL67_RS00810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHL67_RS00815	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHL67_RS00820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHL67_RS00825	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHL67_RS00830	COG1472	Belongs to the glycosyl hydrolase 3 family
CHL67_RS00840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHL67_RS00845	COG0571	ribonuclease III activity
CHL67_RS00850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHL67_RS00855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHL67_RS00860	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS00865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHL67_RS00870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHL67_RS00875	COG0416	fatty acid biosynthetic process
CHL67_RS00880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHL67_RS00900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHL67_RS00905	COG1476	TRANSCRIPTIONal
CHL67_RS00920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL67_RS00930	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHL67_RS00940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHL67_RS00960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHL67_RS00965	COG1993	acr, cog1993
CHL67_RS00970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHL67_RS00975	COG1381	Involved in DNA repair and RecF pathway recombination
CHL67_RS00990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHL67_RS01010	COG0135	phosphoribosylanthranilate isomerase activity
CHL67_RS01020	COG0791	NLP P60 protein
CHL67_RS01025	COG0739	heme binding
CHL67_RS01040	COG0366	Alpha amylase catalytic
CHL67_RS01045	COG0366	Alpha amylase catalytic
CHL67_RS01050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL67_RS01075	COG3956	TIGRFAM MazG family protein
CHL67_RS01085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHL67_RS01095	COG0736	holo-[acyl-carrier-protein] synthase activity
CHL67_RS01105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHL67_RS01110	COG0003	Pfam Anion-transporting ATPase
CHL67_RS01140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHL67_RS01150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHL67_RS01155	COG2226	methyltransferase
CHL67_RS01185	COG3876	Protein conserved in bacteria
CHL67_RS01190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CHL67_RS01205	COG1032	radical SAM domain protein
CHL67_RS01250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL67_RS01265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHL67_RS01270	COG2048	Heterodisulfide reductase, subunit B
CHL67_RS01275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHL67_RS01280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHL67_RS01285	COG0589	response to stress
CHL67_RS01290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CHL67_RS01295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHL67_RS01310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHL67_RS01315	COG0083	homoserine kinase activity
CHL67_RS01320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHL67_RS01325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHL67_RS01335	COG1546	Belongs to the CinA family
CHL67_RS01335	COG1058	Belongs to the CinA family
CHL67_RS01345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHL67_RS01360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHL67_RS01375	COG1355	regulation of microtubule-based process
CHL67_RS01385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHL67_RS01400	COG1216	Glycosyl transferase, family 2
CHL67_RS01405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHL67_RS01415	COG0148	phosphopyruvate hydratase activity
CHL67_RS01425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHL67_RS01430	COG0300	oxidoreductase activity
CHL67_RS01460	COG0250	Participates in transcription elongation, termination and antitermination
CHL67_RS01465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHL67_RS01470	COG0081	regulation of translation
CHL67_RS01475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHL67_RS01480	COG0222	ribosome binding
CHL67_RS01485	COG0085	RNA polymerase activity
CHL67_RS01490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHL67_RS01495	COG0439	Biotin carboxylase
CHL67_RS01505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHL67_RS01515	COG0825	malonyl-CoA metabolic process
CHL67_RS01520	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL67_RS01525	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL67_RS01525	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHL67_RS01535	COG0288	reversible hydration of carbon dioxide
CHL67_RS01545	COG2205	protein histidine kinase activity
CHL67_RS01545	COG0784	Response regulator, receiver
CHL67_RS01545	COG5002	protein histidine kinase activity
CHL67_RS01610	COG1216	Glycosyl transferase, family 2
CHL67_RS01625	COG0463	Glycosyl transferase, family 2
CHL67_RS01630	COG0517	IMP dehydrogenase activity
CHL67_RS01630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHL67_RS01640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHL67_RS01650	COG0560	Phosphoserine phosphatase
CHL67_RS01650	COG3830	Belongs to the UPF0237 family
CHL67_RS01660	COG0519	Catalyzes the synthesis of GMP from XMP
CHL67_RS01660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHL67_RS01665	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHL67_RS01670	COG0596	Alpha beta hydrolase
CHL67_RS01725	COG2096	Adenosyltransferase
CHL67_RS01730	COG1797	cobyrinic acid a,c-diamide synthase activity
CHL67_RS01745	COG0542	response to heat
CHL67_RS01750	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CHL67_RS01760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CHL67_RS01765	COG0552	protein localization to endoplasmic reticulum
CHL67_RS01775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHL67_RS01780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHL67_RS01790	COG0305	Participates in initiation and elongation during chromosome replication
CHL67_RS01795	COG1573	uracil-dna glycosylase
CHL67_RS01800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHL67_RS01810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CHL67_RS01810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHL67_RS01815	COG1560	Kdo2-lipid A biosynthetic process
CHL67_RS01845	COG1132	(ABC) transporter
CHL67_RS01860	COG0438	transferase activity, transferring glycosyl groups
CHL67_RS01870	COG0457	Tetratricopeptide repeat
CHL67_RS01875	COG0529	Catalyzes the synthesis of activated sulfate
CHL67_RS01880	COG0175	sulfate reduction
CHL67_RS01885	COG0529	Catalyzes the synthesis of activated sulfate
CHL67_RS01885	COG2895	sulfate adenylyltransferase (ATP) activity
CHL67_RS01915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHL67_RS01930	COG1132	(ABC) transporter
CHL67_RS01940	COG0438	transferase activity, transferring glycosyl groups
CHL67_RS01970	COG0438	transferase activity, transferring glycosyl groups
CHL67_RS01975	COG1215	transferase activity, transferring glycosyl groups
CHL67_RS01995	COG0438	transferase activity, transferring glycosyl groups
CHL67_RS02020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL67_RS02025	COG0124	histidyl-tRNA synthetase
CHL67_RS02040	COG0779	Required for maturation of 30S ribosomal subunits
CHL67_RS02045	COG0195	Participates in both transcription termination and antitermination
CHL67_RS02050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHL67_RS02055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHL67_RS02060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHL67_RS02065	COG0196	riboflavin kinase activity
CHL67_RS02070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHL67_RS02075	COG1561	YicC-like family, N-terminal region
CHL67_RS02080	COG0194	GDP metabolic process
CHL67_RS02100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHL67_RS02105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CHL67_RS02120	COG0758	DNA mediated transformation
CHL67_RS02130	COG1304	FMN binding
CHL67_RS02140	COG1132	(ABC) transporter
CHL67_RS02145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHL67_RS02150	COG0268	Binds directly to 16S ribosomal RNA
CHL67_RS02155	COG0632	four-way junction helicase activity
CHL67_RS02190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CHL67_RS02195	COG2086	electron transfer activity
CHL67_RS02200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHL67_RS02235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHL67_RS02240	COG0154	amidase activity
CHL67_RS02245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHL67_RS02250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHL67_RS02250	COG0517	IMP dehydrogenase activity
CHL67_RS02280	COG1595	DNA-templated transcription, initiation
CHL67_RS02290	COG3011	Protein conserved in bacteria
CHL67_RS02295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHL67_RS02300	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHL67_RS02325	COG3842	ATPase activity
CHL67_RS02335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHL67_RS02340	COG0012	GTP binding
CHL67_RS02345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHL67_RS02350	COG0539	negative regulation of cytoplasmic translation
CHL67_RS02355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHL67_RS02360	COG0772	Belongs to the SEDS family
CHL67_RS02370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL67_RS02375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHL67_RS02390	COG0776	regulation of translation
CHL67_RS02395	COG0730	response to heat
CHL67_RS02400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHL67_RS02405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHL67_RS02465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CHL67_RS02480	COG3206	protein involved in exopolysaccharide biosynthesis
CHL67_RS02480	COG0489	protein tyrosine kinase activity
CHL67_RS02490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHL67_RS02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHL67_RS02525	COG0463	Glycosyl transferase, family 2
CHL67_RS02560	COG0438	transferase activity, transferring glycosyl groups
CHL67_RS02570	COG1215	transferase activity, transferring glycosyl groups
CHL67_RS02585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CHL67_RS02590	COG0579	oxidoreductase
CHL67_RS02595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHL67_RS02610	COG0318	PFAM AMP-dependent synthetase and ligase
CHL67_RS02620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHL67_RS02625	COG0367	asparagine synthase
CHL67_RS02640	COG1091	dTDP-4-dehydrorhamnose reductase activity
CHL67_RS02645	COG1091	dTDP-4-dehydrorhamnose reductase activity
CHL67_RS02665	COG0662	Cupin 2, conserved barrel domain protein
CHL67_RS02665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CHL67_RS02680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHL67_RS02690	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHL67_RS02705	COG2177	Part of the ABC transporter FtsEX involved in
CHL67_RS02710	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHL67_RS02715	COG0463	Glycosyl transferase, family 2
CHL67_RS02720	COG0602	queuosine metabolic process
CHL67_RS02725	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHL67_RS02730	COG0138	bifunctional purine biosynthesis protein purh
CHL67_RS02740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHL67_RS02745	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL67_RS02750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHL67_RS02760	COG1127	ABC transporter
CHL67_RS02765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHL67_RS02775	COG1968	undecaprenyl-diphosphatase activity
CHL67_RS02780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHL67_RS02785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CHL67_RS02795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHL67_RS02805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHL67_RS02815	COG2814	Major facilitator Superfamily
CHL67_RS02825	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
CHL67_RS02830	COG0438	transferase activity, transferring glycosyl groups
CHL67_RS02835	COG1077	Cell shape determining protein MreB Mrl
CHL67_RS02840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHL67_RS02845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHL67_RS02850	COG1049	propionate catabolic process, 2-methylcitrate cycle
CHL67_RS02905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHL67_RS02910	COG1230	cation diffusion facilitator family transporter
CHL67_RS02915	COG0557	exoribonuclease II activity
CHL67_RS02930	COG0519	Catalyzes the synthesis of GMP from XMP
CHL67_RS02930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHL67_RS02960	COG0330	HflC and HflK could
CHL67_RS02985	COG0133	tryptophan synthase activity
CHL67_RS02990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CHL67_RS03005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHL67_RS03015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHL67_RS03020	COG0459	protein refolding
CHL67_RS03025	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHL67_RS03035	COG0159	tryptophan synthase activity
CHL67_RS03075	COG2154	pterin-4-alpha-carbinolamine dehydratase
CHL67_RS03090	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHL67_RS03095	COG0003	Pfam Anion-transporting ATPase
CHL67_RS03100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHL67_RS03135	COG2884	Cell division ATP-binding protein ftsE
CHL67_RS03140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHL67_RS03150	COG1519	Transferase
CHL67_RS03185	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHL67_RS03200	COG4974	Belongs to the 'phage' integrase family
CHL67_RS03205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHL67_RS03205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHL67_RS03210	COG2873	o-acetylhomoserine
CHL67_RS03215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHL67_RS03220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHL67_RS03230	COG4221	oxidoreductase activity
CHL67_RS03235	COG1278	Cold shock
CHL67_RS03240	COG2003	Belongs to the UPF0758 family
CHL67_RS03245	COG0039	L-malate dehydrogenase activity
CHL67_RS03250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHL67_RS03255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHL67_RS03265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHL67_RS03270	COG1032	radical SAM domain protein
CHL67_RS03275	COG1132	(ABC) transporter
CHL67_RS03290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CHL67_RS03295	COG2204	response regulator
CHL67_RS03305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CHL67_RS03310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHL67_RS03310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHL67_RS03315	COG2252	PERMEase
CHL67_RS03320	COG0450	alkyl hydroperoxide reductase
CHL67_RS03325	COG0442	prolyl-tRNA aminoacylation
CHL67_RS03340	COG2890	protein-(glutamine-N5) methyltransferase activity
CHL67_RS03345	COG1420	regulation of RNA biosynthetic process
CHL67_RS03350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHL67_RS03355	COG0484	heat shock protein binding
CHL67_RS03365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CHL67_RS03370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHL67_RS03375	COG2211	Major facilitator Superfamily
CHL67_RS03380	COG1136	(ABC) transporter
CHL67_RS03385	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHL67_RS03390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHL67_RS03410	COG0242	peptide deformylase activity
CHL67_RS03415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHL67_RS03420	COG0481	GTPase activity
CHL67_RS03445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHL67_RS03455	COG0149	triose-phosphate isomerase activity
CHL67_RS03460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHL67_RS03470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHL67_RS03470	COG0731	radical SAM domain protein
CHL67_RS03500	COG0513	Belongs to the DEAD box helicase family
CHL67_RS03510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL67_RS03525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHL67_RS03530	COG0113	porphobilinogen synthase activity
CHL67_RS03550	COG0735	belongs to the Fur family
CHL67_RS03555	COG0450	alkyl hydroperoxide reductase
CHL67_RS03575	COG1587	Uroporphyrinogen-III synthase
CHL67_RS03580	COG0181	hydroxymethylbilane synthase activity
CHL67_RS03585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHL67_RS03595	COG1217	gtp-binding protein TYPA
CHL67_RS03600	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CHL67_RS03605	COG1063	alcohol dehydrogenase
CHL67_RS03620	COG0492	ferredoxin-NADP+ reductase activity
CHL67_RS03625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CHL67_RS03630	COG0756	dUTP diphosphatase activity
CHL67_RS03635	COG2204	response regulator
CHL67_RS03645	COG1215	transferase activity, transferring glycosyl groups
CHL67_RS03655	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CHL67_RS03655	COG0493	'glutamate synthase
CHL67_RS03675	COG0432	Pfam Uncharacterised protein family UPF0047
CHL67_RS03685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CHL67_RS03690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHL67_RS03695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHL67_RS03705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHL67_RS03750	COG1032	radical SAM domain protein
CHL67_RS03755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHL67_RS03765	COG0745	RESPONSE REGULATOR receiver
CHL67_RS03770	COG0633	Ferredoxin
CHL67_RS03790	COG0501	Belongs to the peptidase M48B family
CHL67_RS03815	COG1509	lysine 2,3-aminomutase activity
CHL67_RS03825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL67_RS03835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL67_RS03840	COG0343	queuine tRNA-ribosyltransferase activity
CHL67_RS03855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHL67_RS03860	COG1562	ergosterol biosynthetic process
CHL67_RS03865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHL67_RS03870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHL67_RS03910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHL67_RS03915	COG0019	diaminopimelate decarboxylase activity
CHL67_RS03920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CHL67_RS03925	COG0658	competence protein
CHL67_RS03925	COG2333	competence protein COMEC
CHL67_RS03940	COG0494	nUDIX hydrolase
CHL67_RS03945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHL67_RS03950	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHL67_RS03955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHL67_RS03960	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHL67_RS03965	COG3387	PFAM Glycoside hydrolase 15-related
CHL67_RS04000	COG1136	(ABC) transporter
CHL67_RS04020	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHL67_RS04025	COG1832	CoA-binding protein
CHL67_RS04035	COG0095	Lipoate-protein ligase
CHL67_RS04040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHL67_RS04045	COG1183	phosphatidylcholine synthase activity
CHL67_RS04050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHL67_RS04055	COG0047	phosphoribosylformylglycinamidine synthase activity
CHL67_RS04060	COG2270	Major facilitator Superfamily
CHL67_RS04065	COG1295	ribonuclease BN
CHL67_RS04070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHL67_RS04080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHL67_RS04090	COG2226	methyltransferase
CHL67_RS04095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL67_RS04105	COG1032	radical SAM domain protein
CHL67_RS04110	COG2050	protein possibly involved in aromatic compounds catabolism
CHL67_RS04125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHL67_RS04130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHL67_RS04145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHL67_RS04170	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL67_RS04185	COG0488	(ABC) transporter
CHL67_RS04195	COG2204	response regulator
CHL67_RS04215	COG0655	NAD(P)H dehydrogenase (quinone) activity
CHL67_RS04225	COG0564	pseudouridine synthase activity
CHL67_RS04230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL67_RS04235	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CHL67_RS04240	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CHL67_RS04240	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CHL67_RS04245	COG1429	ligase activity, forming nitrogen-metal bonds
CHL67_RS04255	COG0516	GMP reductase activity
CHL67_RS04275	COG2602	Beta-lactamase
CHL67_RS04375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CHL67_RS04410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHL67_RS04435	COG1331	Highly conserved protein containing a thioredoxin domain
CHL67_RS04440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHL67_RS04440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHL67_RS04455	COG0428	transporter
CHL67_RS04465	COG5002	protein histidine kinase activity
CHL67_RS04470	COG0745	RESPONSE REGULATOR receiver
CHL67_RS04475	COG0745	RESPONSE REGULATOR receiver
CHL67_RS04490	COG0463	Glycosyl transferase, family 2
CHL67_RS04500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHL67_RS04510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL67_RS04515	COG1702	phosphate starvation-inducible protein PhoH
CHL67_RS04520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHL67_RS04530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHL67_RS04535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL67_RS04540	COG0596	Alpha beta hydrolase
CHL67_RS04545	COG0193	aminoacyl-tRNA hydrolase activity
CHL67_RS04560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHL67_RS04575	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CHL67_RS04590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHL67_RS04600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CHL67_RS04605	COG0742	ribosomal rna small subunit methyltransferase
CHL67_RS04610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHL67_RS04615	COG0436	Aminotransferase
CHL67_RS04625	COG1774	PSP1 C-terminal conserved region
CHL67_RS04630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHL67_RS04630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHL67_RS04645	COG3876	Protein conserved in bacteria
CHL67_RS04650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHL67_RS04665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHL67_RS04670	COG0424	maF-like protein
CHL67_RS04675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHL67_RS04690	COG0101	tRNA pseudouridine synthase activity
CHL67_RS04695	COG1388	LysM domain
CHL67_RS04695	COG3942	CHAP domain
CHL67_RS04710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHL67_RS04720	COG0456	acetyltransferase
CHL67_RS04730	COG1122	ATPase activity
CHL67_RS04735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHL67_RS04755	COG0864	Transcriptional regulator
CHL67_RS04765	COG0347	Belongs to the P(II) protein family
CHL67_RS04770	COG0004	ammonium transporteR
CHL67_RS04780	COG0166	Belongs to the GPI family
CHL67_RS04785	COG1477	protein flavinylation
CHL67_RS04810	COG2340	Cysteine-rich secretory protein family
CHL67_RS04825	COG0659	secondary active sulfate transmembrane transporter activity
CHL67_RS04840	COG3237	CsbD-like
CHL67_RS04855	COG4657	Part of a membrane complex involved in electron transport
CHL67_RS04860	COG4660	Part of a membrane complex involved in electron transport
CHL67_RS04870	COG4658	electron transport chain
CHL67_RS04875	COG4656	Part of a membrane complex involved in electron transport
CHL67_RS04880	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL67_RS04880	COG2878	Part of a membrane complex involved in electron transport
CHL67_RS04890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHL67_RS04905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHL67_RS04935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL67_RS04940	COG1120	ATPase activity
CHL67_RS04960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHL67_RS04960	COG1648	precorrin-2 dehydrogenase activity
CHL67_RS04980	COG2242	protein methyltransferase activity
CHL67_RS04995	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CHL67_RS05000	COG2096	Adenosyltransferase
CHL67_RS05015	COG0842	Transport permease protein
CHL67_RS05045	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CHL67_RS05055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHL67_RS05080	COG0443	Heat shock 70 kDa protein
CHL67_RS05085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHL67_RS05090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CHL67_RS05115	COG4771	TonB-dependent receptor
CHL67_RS05125	COG0778	Nitroreductase
CHL67_RS05130	COG1492	cobalamin metabolic process
CHL67_RS05135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHL67_RS05140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CHL67_RS05145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHL67_RS05150	COG1120	ATPase activity
CHL67_RS05155	COG0604	alcohol dehydrogenase
CHL67_RS05230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHL67_RS05240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CHL67_RS05260	COG1342	Belongs to the UPF0251 family
CHL67_RS05275	COG1454	alcohol dehydrogenase
CHL67_RS05305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHL67_RS05315	COG1136	(ABC) transporter
CHL67_RS05330	COG2081	HI0933 family
CHL67_RS05365	COG0719	Fe-S assembly protein
CHL67_RS05365	COG1372	Participates in initiation and elongation during chromosome replication
CHL67_RS05380	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CHL67_RS05385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CHL67_RS05395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHL67_RS05405	COG0237	dephospho-CoA kinase activity
CHL67_RS05410	COG0805	protein transport
CHL67_RS05415	COG0142	geranyltranstransferase activity
CHL67_RS05435	COG0038	chloride channel
CHL67_RS05440	COG4603	Belongs to the binding-protein-dependent transport system permease family
CHL67_RS05445	COG3845	ABC transporter
CHL67_RS05455	COG1950	PFAM Membrane protein of
CHL67_RS05460	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHL67_RS05465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHL67_RS05475	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHL67_RS05480	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHL67_RS05485	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHL67_RS05490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHL67_RS05510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHL67_RS05515	COG0563	adenylate kinase activity
CHL67_RS05525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHL67_RS05555	COG3568	Endonuclease Exonuclease Phosphatase
CHL67_RS05555	COG1555	photosystem II stabilization
CHL67_RS05575	COG3609	addiction module antidote protein, CC2985 family
CHL67_RS05615	COG2813	Specifically methylates the guanine in position
CHL67_RS05645	COG2226	methyltransferase
CHL67_RS05650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHL67_RS05680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CHL67_RS05685	COG1509	lysine 2,3-aminomutase activity
CHL67_RS05695	COG1215	transferase activity, transferring glycosyl groups
CHL67_RS05720	COG0318	PFAM AMP-dependent synthetase and ligase
CHL67_RS05745	COG0724	RNA recognition motif
CHL67_RS05765	COG1796	DNA polymerase
CHL67_RS05765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHL67_RS05770	COG0511	ligase activity, forming carbon-carbon bonds
CHL67_RS05775	COG0439	Biotin carboxylase
CHL67_RS05785	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHL67_RS05795	COG0641	radical SAM
CHL67_RS05805	COG3278	Belongs to the heme-copper respiratory oxidase family
CHL67_RS05905	COG0633	Ferredoxin
CHL67_RS05910	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS05925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHL67_RS05940	COG1595	DNA-templated transcription, initiation
CHL67_RS05945	COG2217	Heavy metal translocating P-type atpase
CHL67_RS05970	COG3111	PFAM Bacterial OB fold (BOF) protein
CHL67_RS05980	COG0745	RESPONSE REGULATOR receiver
CHL67_RS05985	COG5002	protein histidine kinase activity
CHL67_RS05990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHL67_RS05995	COG0045	succinate-CoA ligase (ADP-forming) activity
CHL67_RS06000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHL67_RS06005	COG0390	transport system, permease component
CHL67_RS06010	COG4619	ABC transporter
CHL67_RS06020	COG2119	membrane
CHL67_RS06035	COG1773	rubredoxin
CHL67_RS06045	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHL67_RS06050	COG3706	GGDEF domain
CHL67_RS06050	COG5001	Diguanylate cyclase
CHL67_RS06050	COG2203	Gaf domain
CHL67_RS06050	COG4251	negative regulation of phosphorylation
CHL67_RS06060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHL67_RS06065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHL67_RS06070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHL67_RS06075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHL67_RS06080	COG1438	arginine binding
CHL67_RS06085	COG0137	argininosuccinate synthase activity
CHL67_RS06125	COG1337	RAMP superfamily
CHL67_RS06140	COG0165	Argininosuccinate lyase
CHL67_RS06145	COG0793	Belongs to the peptidase S41A family
CHL67_RS06150	COG0191	fructose-bisphosphate aldolase activity
CHL67_RS06155	COG1473	amidohydrolase
CHL67_RS06165	COG0698	ribose 5-phosphate isomerase
CHL67_RS06170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHL67_RS06175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHL67_RS06180	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHL67_RS06185	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHL67_RS06195	COG2897	thiosulfate sulfurtransferase activity
CHL67_RS06200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHL67_RS06200	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHL67_RS06225	COG2176	DNA-directed DNA polymerase activity
CHL67_RS06230	COG0517	IMP dehydrogenase activity
CHL67_RS06235	COG1088	dTDP-glucose 4,6-dehydratase activity
CHL67_RS06245	COG1744	ABC transporter substrate-binding protein PnrA-like
CHL67_RS06260	COG1192	Involved in chromosome partitioning
CHL67_RS06280	COG1194	a g-specific adenine glycosylase
CHL67_RS06285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL67_RS06290	COG0335	large ribosomal subunit rRNA binding
CHL67_RS06295	COG0336	Belongs to the RNA methyltransferase TrmD family
CHL67_RS06300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHL67_RS06305	COG0228	four-way junction DNA binding
CHL67_RS06310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHL67_RS06315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHL67_RS06315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CHL67_RS06330	COG3409	Peptidoglycan-binding domain 1 protein
CHL67_RS06330	COG0793	Belongs to the peptidase S41A family
CHL67_RS06345	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CHL67_RS06350	COG0352	thiamine-phosphate diphosphorylase activity
CHL67_RS06355	COG0352	thiamine-phosphate diphosphorylase activity
CHL67_RS06360	COG0351	phosphomethylpyrimidine kinase
CHL67_RS06360	COG0352	thiamine-phosphate diphosphorylase activity
CHL67_RS06385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHL67_RS06390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CHL67_RS06395	COG0653	protein targeting
CHL67_RS06400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHL67_RS06405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHL67_RS06405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHL67_RS06420	COG0596	Alpha beta hydrolase
CHL67_RS06440	COG0436	Aminotransferase
CHL67_RS06455	COG0277	FAD linked oxidase domain protein
CHL67_RS06470	COG1215	transferase activity, transferring glycosyl groups
CHL67_RS06500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHL67_RS06505	COG0581	inorganic phosphate transmembrane transporter activity
CHL67_RS06510	COG0573	inorganic phosphate transmembrane transporter activity
CHL67_RS06515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHL67_RS06545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHL67_RS06590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL67_RS06610	COG2204	response regulator
CHL67_RS06620	COG0492	ferredoxin-NADP+ reductase activity
CHL67_RS06625	COG3118	belongs to the thioredoxin family
CHL67_RS06635	COG0297	glycogen (starch) synthase activity
CHL67_RS06665	COG0589	response to stress
CHL67_RS06680	COG0326	Molecular chaperone. Has ATPase activity
CHL67_RS06685	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CHL67_RS06710	COG2326	polyphosphate kinase activity
CHL67_RS06735	COG0659	secondary active sulfate transmembrane transporter activity
CHL67_RS06740	COG0667	Aldo Keto reductase
CHL67_RS06755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHL67_RS06780	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CHL67_RS06780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHL67_RS06785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHL67_RS06790	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHL67_RS06795	COG3958	Transketolase
CHL67_RS06800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHL67_RS06810	COG0346	lactoylglutathione lyase activity
CHL67_RS06815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHL67_RS06820	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHL67_RS06820	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHL67_RS06825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHL67_RS06825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHL67_RS06830	COG1703	isobutyryl-CoA mutase activity
CHL67_RS06835	COG0589	response to stress
CHL67_RS06840	COG0330	HflC and HflK could
CHL67_RS06845	COG1030	water channel activity
CHL67_RS06850	COG2738	Putative neutral zinc metallopeptidase
CHL67_RS06865	COG3773	Cell wall hydrolase
CHL67_RS06865	COG3409	Peptidoglycan-binding domain 1 protein
CHL67_RS06890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CHL67_RS06910	COG2176	DNA-directed DNA polymerase activity
CHL67_RS06925	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL67_RS06930	COG4106	trans-aconitate 2-methyltransferase activity
CHL67_RS06950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CHL67_RS06975	COG3118	belongs to the thioredoxin family
CHL67_RS06985	COG0302	gtp cyclohydrolase
CHL67_RS06995	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CHL67_RS07010	COG1007	ATP synthesis coupled electron transport
CHL67_RS07020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHL67_RS07025	COG0713	ATP synthesis coupled electron transport
CHL67_RS07040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHL67_RS07045	COG0649	NAD binding
CHL67_RS07050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHL67_RS07055	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHL67_RS07060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHL67_RS07110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHL67_RS07110	COG4651	solute:proton antiporter activity
CHL67_RS07115	COG0589	response to stress
CHL67_RS07120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHL67_RS07130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHL67_RS07140	COG2314	TM2 domain
CHL67_RS07145	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CHL67_RS07150	COG1129	ABC transporter
CHL67_RS07180	COG0795	lipopolysaccharide-transporting ATPase activity
CHL67_RS07190	COG1597	lipid kinase activity
CHL67_RS07225	COG0131	Imidazoleglycerol-phosphate dehydratase
CHL67_RS07230	COG1418	mRNA catabolic process
CHL67_RS07245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHL67_RS07245	COG0072	phenylalanine-tRNA ligase activity
CHL67_RS07300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHL67_RS07305	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CHL67_RS07315	COG0135	phosphoribosylanthranilate isomerase activity
CHL67_RS07330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHL67_RS07335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHL67_RS07345	COG1592	Rubrerythrin
CHL67_RS07395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHL67_RS07420	COG0686	Belongs to the AlaDH PNT family
CHL67_RS07425	COG0456	acetyltransferase
CHL67_RS07425	COG1214	PFAM Peptidase M22, glycoprotease
CHL67_RS07445	COG0494	nUDIX hydrolase
CHL67_RS07460	COG1074	ATP-dependent DNA helicase activity
CHL67_RS07470	COG0419	ATPase involved in DNA repair
CHL67_RS07480	COG0420	3'-5' exonuclease activity
CHL67_RS07525	COG1678	Uncharacterized ACR, COG1678
CHL67_RS07530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHL67_RS07540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHL67_RS07545	COG0668	transmembrane transport
CHL67_RS07550	COG5002	protein histidine kinase activity
CHL67_RS07555	COG0745	RESPONSE REGULATOR receiver
CHL67_RS07560	COG0444	Belongs to the ABC transporter superfamily
CHL67_RS07565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHL67_RS07570	COG0633	Ferredoxin
CHL67_RS07575	COG0633	Ferredoxin
CHL67_RS07595	COG1595	DNA-templated transcription, initiation
CHL67_RS07610	COG0071	Belongs to the small heat shock protein (HSP20) family
CHL67_RS07615	COG0443	Heat shock 70 kDa protein
CHL67_RS07635	COG2885	chlorophyll binding
CHL67_RS07645	COG0823	Involved in the tonB-independent uptake of proteins
CHL67_RS07655	COG0848	biopolymer transport protein
CHL67_RS07660	COG0811	peptide transport
CHL67_RS07670	COG0129	dihydroxy-acid dehydratase activity
CHL67_RS07675	COG0028	Belongs to the TPP enzyme family
CHL67_RS07680	COG0440	acetolactate synthase activity
CHL67_RS07685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHL67_RS07690	COG0473	3-isopropylmalate dehydrogenase activity
CHL67_RS07695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL67_RS07700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHL67_RS07705	COG0066	3-isopropylmalate dehydratase activity
CHL67_RS07710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHL67_RS07720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CHL67_RS07755	COG1575	Belongs to the MenA family. Type 1 subfamily
CHL67_RS07760	COG0492	ferredoxin-NADP+ reductase activity
CHL67_RS07770	COG0107	imidazoleglycerol-phosphate synthase activity
CHL67_RS07785	COG1032	radical SAM domain protein
CHL67_RS07830	COG0598	Magnesium transport protein CorA
CHL67_RS07850	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CHL67_RS07855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHL67_RS07870	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHL67_RS07875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CHL67_RS07895	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CHL67_RS07905	COG0347	Belongs to the P(II) protein family
CHL67_RS07930	COG1433	Dinitrogenase iron-molybdenum cofactor
CHL67_RS07930	COG0535	radical SAM domain protein
CHL67_RS07965	COG0298	carbon dioxide binding
CHL67_RS07975	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHL67_RS07985	COG0375	protein maturation
CHL67_RS07990	COG0540	Belongs to the ATCase OTCase family
CHL67_RS08015	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHL67_RS08020	COG0322	excinuclease ABC activity
CHL67_RS08030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHL67_RS08035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHL67_RS08040	COG0084	hydrolase, TatD family'
CHL67_RS08060	COG0436	Aminotransferase
CHL67_RS08065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHL67_RS08070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CHL67_RS08085	COG1271	oxidase subunit
CHL67_RS08090	COG1294	oxidase, subunit
CHL67_RS08095	COG4988	ABC transporter
CHL67_RS08100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHL67_RS08105	COG3040	lipid binding
CHL67_RS08110	COG0788	formyltetrahydrofolate deformylase activity
CHL67_RS08115	COG0671	phosphoesterase, PA-phosphatase related
CHL67_RS08125	COG0463	Glycosyl transferase, family 2
CHL67_RS08135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHL67_RS08135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CHL67_RS08140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CHL67_RS08145	COG1692	metallophosphoesterase
CHL67_RS08150	COG1741	Belongs to the pirin family
CHL67_RS08160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHL67_RS08165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHL67_RS08185	COG0768	penicillin binding
CHL67_RS08190	COG0277	FAD linked oxidase domain protein
CHL67_RS08195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHL67_RS08200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHL67_RS08205	COG1945	arginine decarboxylase activity
CHL67_RS08210	COG0586	Pfam SNARE associated Golgi protein
CHL67_RS08220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CHL67_RS08225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHL67_RS08240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHL67_RS08290	COG1785	Belongs to the alkaline phosphatase family
CHL67_RS08340	COG0641	radical SAM
CHL67_RS08355	COG1012	belongs to the aldehyde dehydrogenase family
CHL67_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS08380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHL67_RS08450	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CHL67_RS08455	COG2003	Belongs to the UPF0758 family
CHL67_RS08490	COG3846	protein secretion by the type IV secretion system
CHL67_RS08505	COG3451	type IV secretory pathway VirB4
CHL67_RS08515	COG3838	Conjugal transfer protein Trbc
CHL67_RS08520	COG4962	Type ii secretion system protein e
CHL67_RS08565	COG0455	bacterial-type flagellum organization
CHL67_RS08585	COG4974	Belongs to the 'phage' integrase family
CHL67_RS08595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHL67_RS08605	COG0493	'glutamate synthase
CHL67_RS08610	COG0070	glutamate synthase
CHL67_RS08610	COG0069	glutamate synthase activity
CHL67_RS08610	COG0067	glutamate synthase
CHL67_RS08615	COG0588	phosphoglycerate mutase activity
CHL67_RS08620	COG2070	2-Nitropropane dioxygenase
CHL67_RS08630	COG0590	tRNA wobble adenosine to inosine editing
CHL67_RS08635	COG0045	succinate-CoA ligase (ADP-forming) activity
CHL67_RS08640	COG0189	ligase activity
CHL67_RS08655	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CHL67_RS08660	COG0488	(ABC) transporter
CHL67_RS08665	COG0778	Nitroreductase
CHL67_RS08675	COG0673	inositol 2-dehydrogenase activity
CHL67_RS08680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHL67_RS08685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHL67_RS08705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHL67_RS08730	COG0811	peptide transport
CHL67_RS08735	COG0358	DNA primase activity
CHL67_RS08750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHL67_RS08755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL67_RS08755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL67_RS08760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHL67_RS08835	COG4771	TonB-dependent receptor
CHL67_RS08850	COG4771	TonB-dependent receptor
CHL67_RS08855	COG0811	peptide transport
CHL67_RS08860	COG0848	biopolymer transport protein
CHL67_RS08880	COG0716	FMN binding
CHL67_RS08885	COG1528	Iron-storage protein
CHL67_RS08925	COG3152	Membrane
CHL67_RS08935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHL67_RS08940	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHL67_RS08945	COG0205	6-phosphofructokinase activity
CHL67_RS08950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHL67_RS08955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHL67_RS08970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHL67_RS08975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHL67_RS08980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHL67_RS08985	COG0328	RNA-DNA hybrid ribonuclease activity
CHL67_RS08995	COG0037	tRNA processing
CHL67_RS09000	COG0688	phosphatidylethanolamine metabolic process
CHL67_RS09005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHL67_RS09015	COG0497	DNA recombination
CHL67_RS09020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHL67_RS09025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHL67_RS09030	COG0509	glycine decarboxylation via glycine cleavage system
CHL67_RS09035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL67_RS09040	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHL67_RS09040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHL67_RS09040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CHL67_RS09040	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHL67_RS09050	COG2255	four-way junction helicase activity
CHL67_RS09055	COG0601	transmembrane transport
CHL67_RS09065	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHL67_RS09075	COG4974	Belongs to the 'phage' integrase family
CHL67_RS09085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHL67_RS09090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHL67_RS09095	COG3245	cytochrome
CHL67_RS09100	COG0606	chelatase, subunit chli
CHL67_RS09110	COG1051	belongs to the nudix hydrolase family
CHL67_RS09115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHL67_RS09120	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL67_RS09120	COG0596	Alpha beta hydrolase
CHL67_RS09130	COG0616	signal peptide processing
CHL67_RS09135	COG4608	Belongs to the ABC transporter superfamily
CHL67_RS09140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHL67_RS09145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHL67_RS09150	COG1185	polyribonucleotide nucleotidyltransferase activity
CHL67_RS09155	COG0495	leucyl-tRNA aminoacylation
CHL67_RS09160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHL67_RS09175	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CHL67_RS09180	COG0483	inositol monophosphate 1-phosphatase activity
CHL67_RS09185	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CHL67_RS09185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHL67_RS09190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHL67_RS09195	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CHL67_RS09200	COG0217	transcriptional regulatory protein
CHL67_RS09205	COG1605	Chorismate mutase
CHL67_RS09205	COG0077	Prephenate dehydratase
CHL67_RS09210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL67_RS09210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHL67_RS09215	COG0739	heme binding
CHL67_RS09230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHL67_RS09235	COG0134	indole-3-glycerol-phosphate synthase activity
CHL67_RS09240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHL67_RS09250	COG0151	Belongs to the GarS family
CHL67_RS09260	COG1663	tetraacyldisaccharide 4'-kinase activity
CHL67_RS09280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CHL67_RS09295	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CHL67_RS09300	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHL67_RS09305	COG0574	Belongs to the PEP-utilizing enzyme family
CHL67_RS09305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHL67_RS09310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHL67_RS09315	COG0546	phosphoglycolate phosphatase activity
CHL67_RS09330	COG0640	Transcriptional regulator
CHL67_RS09345	COG1032	radical SAM domain protein
CHL67_RS09350	COG1151	hydroxylamine reductase activity
CHL67_RS09365	COG1959	2 iron, 2 sulfur cluster binding
CHL67_RS09370	COG2226	methyltransferase
CHL67_RS09385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHL67_RS09390	COG1196	nuclear chromosome segregation
CHL67_RS09400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHL67_RS09425	COG0248	Ppx GppA phosphatase
CHL67_RS09435	COG0009	L-threonylcarbamoyladenylate synthase
CHL67_RS09445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHL67_RS09450	COG0456	acetyltransferase
CHL67_RS09455	COG2226	methyltransferase
CHL67_RS09470	COG0535	radical SAM domain protein
CHL67_RS09495	COG1187	pseudouridine synthase activity
CHL67_RS09500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHL67_RS09505	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHL67_RS09510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHL67_RS09520	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHL67_RS09520	COG0493	'glutamate synthase
CHL67_RS09545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHL67_RS09550	COG2226	methyltransferase
CHL67_RS09565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHL67_RS09575	COG1136	(ABC) transporter
CHL67_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS09600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHL67_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS09625	COG1830	Aldolase
CHL67_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS09630	COG3347	Dehydrogenase
CHL67_RS09635	COG2137	regulation of response to DNA damage stimulus
CHL67_RS09640	COG0528	UMP kinase activity
CHL67_RS09645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHL67_RS09650	COG0052	Belongs to the universal ribosomal protein uS2 family
CHL67_RS09655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHL67_RS09660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHL67_RS09665	COG1160	GTP binding
CHL67_RS09670	COG0489	protein tyrosine kinase activity
CHL67_RS09675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CHL67_RS09680	COG1674	ftsk spoiiie
CHL67_RS09685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHL67_RS09715	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CHL67_RS09720	COG1704	LemA family
CHL67_RS09730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHL67_RS09735	COG0556	nucleotide-excision repair
CHL67_RS09740	COG0612	Peptidase, M16
CHL67_RS09765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHL67_RS09770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHL67_RS09775	COG0525	valine-tRNA ligase activity
CHL67_RS09780	COG0740	serine-type endopeptidase activity
CHL67_RS09785	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CHL67_RS09790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHL67_RS09795	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHL67_RS09800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CHL67_RS09805	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CHL67_RS09815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHL67_RS09830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHL67_RS09835	COG1611	Belongs to the LOG family
CHL67_RS09840	COG0512	Glutamine amidotransferase of anthranilate synthase
CHL67_RS09840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHL67_RS09850	COG1597	lipid kinase activity
CHL67_RS09885	COG1012	belongs to the aldehyde dehydrogenase family
CHL67_RS09890	COG1162	GTPase activity
CHL67_RS09895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHL67_RS09900	COG0254	rRNA binding
CHL67_RS09905	COG0233	cytoplasmic translational termination
CHL67_RS09910	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHL67_RS09920	COG1570	exodeoxyribonuclease VII activity
CHL67_RS09925	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CHL67_RS09930	COG1490	D-aminoacyl-tRNA deacylase activity
CHL67_RS09935	COG1872	DUF167
CHL67_RS09940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHL67_RS09945	COG0372	Belongs to the citrate synthase family
CHL67_RS09950	COG1115	amino acid carrier protein
CHL67_RS09960	COG2885	chlorophyll binding
CHL67_RS09970	COG2217	Heavy metal translocating P-type atpase
CHL67_RS09990	COG1169	isochorismate synthase
CHL67_RS09995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CHL67_RS10015	COG0318	PFAM AMP-dependent synthetase and ligase
CHL67_RS10025	COG2076	Multidrug Resistance protein
CHL67_RS10030	COG1902	pentaerythritol trinitrate reductase activity
CHL67_RS10040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHL67_RS10050	COG1475	DNA binding
CHL67_RS10055	COG1192	Involved in chromosome partitioning
CHL67_RS10060	COG2094	Belongs to the DNA glycosylase MPG family
CHL67_RS10065	COG2239	Acts as a magnesium transporter
CHL67_RS10070	COG0644	oxidoreductase
CHL67_RS10070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CHL67_RS10075	COG0482	sulfurtransferase activity
CHL67_RS10080	COG0400	carboxylic ester hydrolase activity
CHL67_RS10085	COG1410	methionine synthase
CHL67_RS10085	COG0646	methionine synthase
CHL67_RS10090	COG2989	Protein conserved in bacteria
CHL67_RS10125	COG3264	Mechanosensitive ion channel
CHL67_RS10125	COG1196	nuclear chromosome segregation
CHL67_RS10135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHL67_RS10140	COG0363	glucosamine-6-phosphate deaminase activity
CHL67_RS10145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHL67_RS10150	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CHL67_RS10195	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHL67_RS10200	COG1012	belongs to the aldehyde dehydrogenase family
CHL67_RS10205	COG0861	Integral membrane protein TerC family
CHL67_RS10210	COG1067	ATP-dependent peptidase activity
CHL67_RS10220	COG2095	MarC family integral membrane protein
CHL67_RS10225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHL67_RS10235	COG0826	peptidase U32
CHL67_RS10260	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHL67_RS10270	COG1047	Peptidyl-prolyl cis-trans
CHL67_RS10275	COG3264	Mechanosensitive ion channel
CHL67_RS10275	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CHL67_RS10280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHL67_RS10285	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHL67_RS10290	COG1137	ATPase activity
CHL67_RS10295	COG1032	radical SAM domain protein
CHL67_RS10300	COG1078	dGTPase activity
CHL67_RS10315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHL67_RS10320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHL67_RS10335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHL67_RS10350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHL67_RS10355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHL67_RS10360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHL67_RS10370	COG0612	Peptidase, M16
CHL67_RS10375	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHL67_RS10410	COG0003	Pfam Anion-transporting ATPase
CHL67_RS10420	COG0629	single-stranded DNA binding
CHL67_RS10430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHL67_RS10435	COG0156	8-amino-7-oxononanoate synthase activity
CHL67_RS10440	COG4206	TonB-dependent receptor
CHL67_RS10445	COG1429	ligase activity, forming nitrogen-metal bonds
CHL67_RS10455	COG1429	ligase activity, forming nitrogen-metal bonds
CHL67_RS10470	COG0071	Belongs to the small heat shock protein (HSP20) family
CHL67_RS10480	COG3174	membrane
CHL67_RS10490	COG2133	pyrroloquinoline quinone binding
CHL67_RS10515	COG1216	Glycosyl transferase, family 2
CHL67_RS10520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHL67_RS10535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHL67_RS10540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHL67_RS10550	COG1104	cysteine desulfurase activity
CHL67_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
CHL67_RS10575	COG1253	flavin adenine dinucleotide binding
CHL67_RS10580	COG0105	UTP biosynthetic process
CHL67_RS10585	COG1686	Belongs to the peptidase S11 family
CHL67_RS10595	COG0628	permease
CHL67_RS10600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHL67_RS10605	COG1040	competence protein
CHL67_RS10615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHL67_RS10630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHL67_RS10635	COG0297	glycogen (starch) synthase activity
CHL67_RS10665	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CHL67_RS10670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHL67_RS10675	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHL67_RS10710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHL67_RS10715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHL67_RS10720	COG0215	cysteine-tRNA ligase activity
CHL67_RS10725	COG0662	Cupin 2, conserved barrel domain protein
CHL67_RS10725	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CHL67_RS10730	COG0357	Ribosomal RNA small subunit methyltransferase G
CHL67_RS10735	COG0203	ribosomal protein L17
CHL67_RS10740	COG0202	RNA polymerase activity
CHL67_RS10745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHL67_RS10750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHL67_RS10755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHL67_RS10760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHL67_RS10765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHL67_RS10780	COG0200	Binds to the 23S rRNA
CHL67_RS10785	COG1841	ribosomal large subunit assembly
CHL67_RS10790	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHL67_RS10795	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHL67_RS10800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHL67_RS10805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHL67_RS10810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHL67_RS10815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHL67_RS10820	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHL67_RS10830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHL67_RS10835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHL67_RS10840	COG0255	Belongs to the universal ribosomal protein uL29 family
CHL67_RS10845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHL67_RS10850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHL67_RS10855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHL67_RS10860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHL67_RS10865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHL67_RS10870	COG0089	rRNA binding
CHL67_RS10875	COG0088	Forms part of the polypeptide exit tunnel
CHL67_RS10880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHL67_RS10885	COG0051	transcription antitermination factor activity, RNA binding
CHL67_RS10890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHL67_RS10895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHL67_RS10900	COG0049	tRNA binding
CHL67_RS10905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHL67_RS10930	COG0297	glycogen (starch) synthase activity
CHL67_RS10935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHL67_RS10940	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CHL67_RS10945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHL67_RS10950	COG1722	exodeoxyribonuclease VII activity
CHL67_RS10955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHL67_RS10965	COG0542	response to heat
CHL67_RS10970	COG0069	glutamate synthase activity
CHL67_RS11005	COG0714	Associated with various cellular activities
CHL67_RS11015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHL67_RS11025	COG1862	Preprotein translocase
CHL67_RS11030	COG0505	Belongs to the CarA family
CHL67_RS11060	COG0641	radical SAM
CHL67_RS11070	COG0385	Bile acid
CHL67_RS11080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHL67_RS11090	COG0314	molybdopterin synthase activity
CHL67_RS11100	COG0303	'Molybdopterin
CHL67_RS11105	COG0315	cyclic pyranopterin monophosphate synthase activity
CHL67_RS11105	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHL67_RS11110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHL67_RS11135	COG0315	cyclic pyranopterin monophosphate synthase activity
CHL67_RS11135	COG0746	molybdenum cofactor guanylyltransferase activity
CHL67_RS11145	COG2871	sodium ion transport
CHL67_RS11150	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CHL67_RS11155	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CHL67_RS11160	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CHL67_RS11170	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CHL67_RS11175	COG0243	molybdopterin cofactor binding
CHL67_RS11180	COG0437	4 iron, 4 sulfur cluster binding
CHL67_RS11185	COG3301	Polysulphide reductase, NrfD
CHL67_RS11220	COG4106	trans-aconitate 2-methyltransferase activity
CHL67_RS11260	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHL67_RS11265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHL67_RS11270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHL67_RS11280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHL67_RS11295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CHL67_RS11300	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CHL67_RS11305	COG0542	response to heat
CHL67_RS11315	COG1472	Belongs to the glycosyl hydrolase 3 family
CHL67_RS11325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHL67_RS11330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHL67_RS11335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHL67_RS11340	COG0527	aspartate kinase activity
CHL67_RS11345	COG0791	NLP P60 protein
CHL67_RS11350	COG2264	protein methyltransferase activity
CHL67_RS11355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHL67_RS11355	COG0248	Ppx GppA phosphatase
CHL67_RS11365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHL67_RS11370	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CHL67_RS11375	COG4106	trans-aconitate 2-methyltransferase activity
CHL67_RS11385	COG0156	8-amino-7-oxononanoate synthase activity
CHL67_RS11390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHL67_RS11405	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHL67_RS11415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHL67_RS11420	COG1918	ferrous iron import across plasma membrane
CHL67_RS11420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHL67_RS11425	COG1918	ferrous iron import across plasma membrane
CHL67_RS11430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHL67_RS11435	COG0537	adenosine 5'-monophosphoramidase activity
CHL67_RS11450	COG1785	Belongs to the alkaline phosphatase family
CHL67_RS11460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHL67_RS11460	COG0596	Alpha beta hydrolase
CHL67_RS11470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHL67_RS11475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHL67_RS11480	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CHL67_RS11490	COG0180	Tryptophanyl-tRNA synthetase
CHL67_RS11495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHL67_RS11500	COG0018	arginyl-trna synthetase
CHL67_RS11505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHL67_RS11560	COG0515	serine threonine protein kinase
CHL67_RS11560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CHL67_RS11565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CHL67_RS11580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHL67_RS11585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHL67_RS11590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHL67_RS11595	COG0356	it plays a direct role in the translocation of protons across the membrane
CHL67_RS11620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHL67_RS11630	COG1496	oxidoreductase activity
CHL67_RS11640	COG2813	Specifically methylates the guanine in position
CHL67_RS11645	COG0427	acetyl-CoA hydrolase
CHL67_RS11650	COG1053	succinate dehydrogenase
CHL67_RS11665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHL67_RS11680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHL67_RS11685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHL67_RS11690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHL67_RS11695	COG0772	Belongs to the SEDS family
CHL67_RS11700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHL67_RS11705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHL67_RS11710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHL67_RS11715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHL67_RS11730	COG0275	rRNA processing
CHL67_RS11735	COG2001	Belongs to the MraZ family
CHL67_RS11750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHL67_RS11755	COG0126	phosphoglycerate kinase activity
CHL67_RS11785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CHL67_RS11790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHL67_RS11800	COG0671	phosphoesterase, PA-phosphatase related
CHL67_RS11805	COG0706	membrane insertase activity
CHL67_RS11810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHL67_RS11815	COG0594	ribonuclease P activity
CHL67_RS11820	COG0230	Belongs to the bacterial ribosomal protein bL34 family