locus-tag	class	description
GSM99_RS00005	ENOG4108TH4	Major fimbrial subunit
GSM99_RS00010	ENOG4106PG1	outer membrane usher protein
GSM99_RS00015	ENOG4108FZ9	Chaperone
GSM99_RS00020	ENOG4108MDY	Fimbrial
GSM99_RS00025	ENOG4108YUF	Fimbrial
GSM99_RS00030	ENOG4108Z6B	deaminase
GSM99_RS00035	ENOG4105N14	lysine exporter protein LysE YggA
GSM99_RS00040	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GSM99_RS00045	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GSM99_RS00050	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GSM99_RS00055	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GSM99_RS00060	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GSM99_RS00065	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GSM99_RS00070	ENOG4105C3F	Signal peptidase i
GSM99_RS00075	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GSM99_RS00095	ENOG4105EMN	RNA polymerase sigma factor
GSM99_RS00100	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GSM99_RS00110	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GSM99_RS00115	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GSM99_RS00125	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GSM99_RS00135	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GSM99_RS00140	ENOG4105VDB	UPF0125 protein
GSM99_RS00145	ENOG4108Z1B	Cyclase dehydrase
GSM99_RS00150	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GSM99_RS00255	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GSM99_RS00265	ENOG4105CAR	Terminase, large subunit
GSM99_RS00335	ENOG4105HRS	Antitermination protein
GSM99_RS00445	ENOG4107R08	Integrase
GSM99_RS00460	ENOG4107ZY0	Phenazine biosynthesis-like protein
GSM99_RS00470	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS00480	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GSM99_RS00485	ENOG4107QR9	Iron-sulfur cluster binding protein
GSM99_RS00490	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GSM99_RS00505	ENOG4105PI0	Ferredoxin
GSM99_RS00510	ENOG4108XC3	NADH ubiquinone oxidoreductase
GSM99_RS00525	ENOG4105D05	Receptor
GSM99_RS00535	ENOG41060NJ	transcriptional regulator
GSM99_RS00540	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GSM99_RS00550	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GSM99_RS00555	ENOG4105CMR	udp-glucose 4-epimerase
GSM99_RS00570	ENOG4108RW8	Universal stress protein F
GSM99_RS00575	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
GSM99_RS00580	ENOG4105Z2P	Protein of unknown function (DUF465)
GSM99_RS00585	ENOG4105VVZ	metal-binding protein
GSM99_RS00645	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS00655	ENOG4105CRK	lysyL-tRNA synthetase
GSM99_RS00665	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GSM99_RS00670	ENOG4105T95	Thiol disulfide interChange protein
GSM99_RS00675	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSM99_RS00680	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GSM99_RS00690	ENOG4105Y75	tpr repeat protein
GSM99_RS00695	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GSM99_RS00705	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSM99_RS00710	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GSM99_RS00715	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GSM99_RS00720	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GSM99_RS00725	ENOG4105D0A	hydroxylase
GSM99_RS00730	ENOG4107RAQ	aminopeptidase
GSM99_RS00735	ENOG4105E07	UPF0149 protein
GSM99_RS00740	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GSM99_RS00765	ENOG4108JJA	ABC, transporter
GSM99_RS00770	ENOG4108JQ1	Dehydrogenase
GSM99_RS00775	ENOG4105E66	phosphoriboisomerase A
GSM99_RS00785	ENOG4105MPN	Membrane
GSM99_RS00790	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GSM99_RS00795	ENOG4105D64	Mechanosensitive ion channel
GSM99_RS00800	ENOG4108ZIG	UPF0231 protein
GSM99_RS00805	ENOG4107QIJ	Aconitate hydratase 2
GSM99_RS00815	ENOG4107QN2	dihydrolipoyl dehydrogenase
GSM99_RS00825	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GSM99_RS00830	ENOG41073TP	transcriptional regulator
GSM99_RS00835	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GSM99_RS00840	ENOG4108ZUW	Major pilin subunit
GSM99_RS00845	ENOG4107QHF	type ii secretion system protein e
GSM99_RS00850	ENOG4105D7Q	type ii secretion system
GSM99_RS00855	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GSM99_RS00860	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GSM99_RS00865	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GSM99_RS00890	ENOG4108I4D	hemolysin
GSM99_RS00895	ENOG4106IWJ	hemolysin
GSM99_RS00910	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GSM99_RS00915	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
GSM99_RS00925	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GSM99_RS00930	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GSM99_RS00935	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GSM99_RS00940	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GSM99_RS00950	ENOG4105DFU	Cell wall formation (By similarity)
GSM99_RS00955	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GSM99_RS00960	ENOG4105CNI	cell division protein FtsW
GSM99_RS00965	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GSM99_RS00970	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GSM99_RS00975	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GSM99_RS00980	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GSM99_RS00985	ENOG4105CJN	penicillin-binding protein
GSM99_RS00990	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GSM99_RS00995	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GSM99_RS01000	ENOG4108V6E	Cell division protein mraZ
GSM99_RS01005	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GSM99_RS01010	ENOG4108IQE	Amp-dependent synthetase and ligase
GSM99_RS01015	ENOG41064T2	transcriptional regulator, lysR family
GSM99_RS01020	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GSM99_RS01025	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GSM99_RS01030	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GSM99_RS01045	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GSM99_RS01050	ENOG4105CYW	agmatinase
GSM99_RS01055	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GSM99_RS01060	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GSM99_RS01065	ENOG4105D1V	cellulose synthase operon protein YhjU
GSM99_RS01100	ENOG4107QZ7	Cellulose synthase catalytic subunit
GSM99_RS01105	ENOG4107EEX	Cellulose synthase regulator protein
GSM99_RS01110	ENOG4105EJG	cellulose synthase
GSM99_RS01125	ENOG41080HT	Transcriptional regulator, arsr family
GSM99_RS01130	ENOG4105GPY	SprT protein
GSM99_RS01135	ENOG4105CJW	magnesium transporter
GSM99_RS01145	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GSM99_RS01150	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GSM99_RS01155	ENOG4105C26	Dehydrogenase
GSM99_RS01160	ENOG4105BZG	amino acid carrier protein
GSM99_RS01165	ENOG4105CMQ	Chloride channel
GSM99_RS01175	ENOG4107SVH	Potassium channel protein
GSM99_RS01185	ENOG4108YYC	ycei family
GSM99_RS01190	ENOG4105DS1	cytochrome b561
GSM99_RS01210	ENOG4105CBG	Sulfatase
GSM99_RS01235	ENOG4105F5H	Glycosyl Hydrolase Family 88
GSM99_RS01250	ENOG4105CE4	GlcNAc 6-P deacetylase
GSM99_RS01255	ENOG4108EQA	pts system
GSM99_RS01260	ENOG4105F3R	pts system mannose fructose sorbose family iid
GSM99_RS01265	ENOG4105ETZ	PTS System
GSM99_RS01270	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
GSM99_RS01285	ENOG4105E98	transcriptional regulator DeoR family
GSM99_RS01310	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GSM99_RS01315	ENOG4108UHU	Aldolase
GSM99_RS01345	ENOG4105CDV	Ompa motb domain protein
GSM99_RS01355	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GSM99_RS01575	ENOG4105DFP	Integrase
GSM99_RS01585	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GSM99_RS01590	ENOG4105WQ3	Rna-binding protein
GSM99_RS01595	ENOG4105DE4	1-phosphofructokinase
GSM99_RS01605	ENOG4105C8N	cysteinyl-tRNA synthetase
GSM99_RS01610	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GSM99_RS01615	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GSM99_RS01635	ENOG4105D64	Mechanosensitive ion channel
GSM99_RS01645	ENOG4105CV6	ABC transporter, permease
GSM99_RS01650	ENOG4108I0Y	(ABC) transporter
GSM99_RS01655	ENOG4108UJV	acyl-CoA thioesterase i
GSM99_RS01660	ENOG4105E1F	short-chain dehydrogenase reductase
GSM99_RS01665	ENOG4107QR8	Thioredoxin
GSM99_RS01670	ENOG4107QX8	SPFH domain, Band 7 family protein
GSM99_RS01680	ENOG4108Z6Z	Transcriptional regulator
GSM99_RS01685	ENOG4105C59	p-type ATPase
GSM99_RS01695	ENOG4105MBR	gumn family
GSM99_RS01700	ENOG4108Z66	YbaK ebsC protein
GSM99_RS01705	ENOG4105CGH	5'-nucleotidase
GSM99_RS01710	ENOG4105EU0	Major facilitator Superfamily
GSM99_RS01715	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GSM99_RS01720	ENOG4107RE1	Inosine-guanosine kinase
GSM99_RS01725	ENOG4108QY5	Ferric enterobactin transport protein
GSM99_RS01730	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GSM99_RS01735	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GSM99_RS01740	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GSM99_RS01745	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GSM99_RS01750	ENOG4105FR1	rard protein
GSM99_RS01760	ENOG4108HKT	sucrose-6-phosphate hydrolase
GSM99_RS01765	ENOG4106NDP	Transcriptional regulator
GSM99_RS01785	ENOG4108HPI	phosphatidate Cytidylyltransferase
GSM99_RS01795	ENOG4107653	Transcriptional regulator
GSM99_RS01805	ENOG4105C5B	carbamate kinase
GSM99_RS01810	ENOG4105G5A	Protein of unknown function (DUF2877)
GSM99_RS01815	ENOG4107REC	cytoplasmic protein
GSM99_RS01820	ENOG4107R1Q	Membrane protein FdrA
GSM99_RS01825	ENOG4108YYC	ycei family
GSM99_RS01835	ENOG4105EUB	pirin domain protein
GSM99_RS01845	ENOG4107QPK	)-transporter
GSM99_RS01855	ENOG4108WDE	Fimbrial protein
GSM99_RS01870	ENOG4108T65	Fimbrial
GSM99_RS01875	ENOG4105CW0	outer membrane usher protein
GSM99_RS01880	ENOG4108VCD	Chaperone
GSM99_RS01885	ENOG4106EAR	Fimbrial protein
GSM99_RS01895	ENOG4107QPK	)-transporter
GSM99_RS01900	ENOG4105DUM	transcriptional regulator, lysR family
GSM99_RS01910	ENOG4107S01	Repressor protein MetJ
GSM99_RS01935	ENOG4105MZU	cell filamentation protein
GSM99_RS01960	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GSM99_RS01980	ENOG4108K5P	(LipO)protein
GSM99_RS01985	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GSM99_RS01990	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GSM99_RS01995	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GSM99_RS02000	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GSM99_RS02005	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GSM99_RS02010	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GSM99_RS02015	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GSM99_RS02020	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GSM99_RS02025	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GSM99_RS02030	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GSM99_RS02035	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GSM99_RS02040	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GSM99_RS02045	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GSM99_RS02050	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GSM99_RS02060	ENOG4105C85	amino acid
GSM99_RS02080	ENOG4107NA1	Endonuclease Exonuclease phosphatase
GSM99_RS02110	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GSM99_RS02115	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GSM99_RS02120	ENOG4108UMI	ABC transporter, permease
GSM99_RS02125	ENOG4105D01	(LipO)protein
GSM99_RS02135	ENOG4108R96	Methyltransferase, YaeB family
GSM99_RS02150	ENOG4105M1T	rho-binding antiterminator
GSM99_RS02155	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GSM99_RS02170	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GSM99_RS02175	ENOG4105C0B	DNA polymerase III (alpha subunit)
GSM99_RS02180	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GSM99_RS02190	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GSM99_RS02195	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GSM99_RS02200	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GSM99_RS02205	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GSM99_RS02210	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GSM99_RS02220	ENOG4105KNE	Phosphatidate cytidylyltransferase
GSM99_RS02225	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GSM99_RS02230	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GSM99_RS02235	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GSM99_RS02240	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GSM99_RS02245	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GSM99_RS02255	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GSM99_RS02260	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GSM99_RS02265	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GSM99_RS02285	ENOG4105CI1	PTS System
GSM99_RS02290	ENOG4105DR9	pseudouridine synthase
GSM99_RS02295	ENOG4105DR9	pseudouridine synthase
GSM99_RS02300	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GSM99_RS02305	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GSM99_RS02315	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GSM99_RS02325	ENOG4105M08	Membrane
GSM99_RS02330	ENOG4105ETT	transcriptional Regulator, LysR family
GSM99_RS02335	ENOG4105C9B	Cysteine desulfurase
GSM99_RS02340	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GSM99_RS02370	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GSM99_RS02375	ENOG4107QZM	n-acetylglutamate synthase
GSM99_RS02380	ENOG4107QYX	exodeoxyribonuclease v alpha
GSM99_RS02385	ENOG4107QKA	exodeoxyribonuclease V beta
GSM99_RS02390	ENOG4107QXK	peptidase
GSM99_RS02395	ENOG4105DSY	exodeoxyribonuclease V, gamma
GSM99_RS02420	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GSM99_RS02425	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GSM99_RS02430	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GSM99_RS02435	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GSM99_RS02445	ENOG4106SMU	thiamine transporter membrane protein
GSM99_RS02450	ENOG4107T0D	ABC, transporter
GSM99_RS02455	ENOG4105CQ2	DNA polymerase
GSM99_RS02465	ENOG4105D3G	Pseudouridine synthase
GSM99_RS02470	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GSM99_RS02475	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GSM99_RS02480	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GSM99_RS02485	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GSM99_RS02490	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GSM99_RS02495	ENOG4105NWN	ApaG protein
GSM99_RS02500	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GSM99_RS02505	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GSM99_RS02510	ENOG410829K	Lysine exporter protein (Lyse ygga)
GSM99_RS02525	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
GSM99_RS02530	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GSM99_RS02535	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSM99_RS02540	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSM99_RS02545	ENOG4105IPS	esterase
GSM99_RS02550	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GSM99_RS02555	ENOG41087AY	ADP-Ribose pyrophosphatase
GSM99_RS02560	ENOG4105DFG	type I secretion outer membrane protein
GSM99_RS02565	ENOG4105F1G	UPF0441 protein
GSM99_RS02570	ENOG4106032	Glutathionylspermidine synthase
GSM99_RS02575	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GSM99_RS02580	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GSM99_RS02585	ENOG4105W0Z	cytoplasmic protein
GSM99_RS02590	ENOG4105F8D	glycoside hydrolase family 4
GSM99_RS02600	ENOG4105FDP	GntR family transcriptional regulator
GSM99_RS02610	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GSM99_RS02625	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GSM99_RS02630	ENOG4107ZVW	dihydroneopterin aldolase
GSM99_RS02635	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GSM99_RS02640	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GSM99_RS02645	ENOG4105VCC	30S ribosomal protein S21
GSM99_RS02650	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GSM99_RS02655	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSM99_RS02670	ENOG4107927	Cholera enterotoxin, A subunit
GSM99_RS02680	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS02695	ENOG4108VEV	chaperone
GSM99_RS02710	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
GSM99_RS02775	ENOG4108M24	von Willebrand factor, type A
GSM99_RS02805	ENOG410822N	TonB family
GSM99_RS02855	ENOG4105CMT	Dihydroxyacetone kinase
GSM99_RS02860	ENOG4108UTZ	Dihydroxyacetone kinase
GSM99_RS02890	ENOG4108FZ9	Chaperone
GSM99_RS02895	ENOG4106PG1	outer membrane usher protein
GSM99_RS02905	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GSM99_RS02920	ENOG4105CXY	transporter
GSM99_RS02925	ENOG4105CA9	Pyruvate kinase
GSM99_RS02950	ENOG4105KSC	Transcriptional regulator, TraR DksA family
GSM99_RS02965	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GSM99_RS02970	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GSM99_RS02975	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GSM99_RS02980	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GSM99_RS02985	ENOG4105D9N	nucleoside
GSM99_RS02990	ENOG4105EYA	deoxyribonuclease
GSM99_RS03005	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GSM99_RS03010	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GSM99_RS03020	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GSM99_RS03045	ENOG4105EAM	Na Pi-cotransporter
GSM99_RS03055	ENOG4105E93	esterase
GSM99_RS03065	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
GSM99_RS03070	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GSM99_RS03075	ENOG4105EAC	phosphoserine phosphatase
GSM99_RS03080	ENOG41062Z9	Membrane
GSM99_RS03085	ENOG4105G0K	glycine radical enzyme YjjI family
GSM99_RS03090	ENOG41076CZ	activating enzyme
GSM99_RS03100	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
GSM99_RS03110	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS03125	ENOG4105K64	Glycosyl transferase, family 2
GSM99_RS03140	ENOG4108MG9	hydrogenase 3 maturation protease
GSM99_RS03145	ENOG4105I6X	formate hydrogenlyase maturation
GSM99_RS03150	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GSM99_RS03160	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSM99_RS03165	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GSM99_RS03170	ENOG4107WQX	hydrogenase 4 membrane subunit
GSM99_RS03175	ENOG4105D65	subunit l
GSM99_RS03180	ENOG4107TDF	Formate hydrogenlyase subunit 4
GSM99_RS03185	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GSM99_RS03190	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
GSM99_RS03195	ENOG4105EUB	pirin domain protein
GSM99_RS03200	ENOG4108YZG	isomerase
GSM99_RS03205	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GSM99_RS03210	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GSM99_RS03215	ENOG4108ZVF	(LipO)protein
GSM99_RS03220	ENOG4105EEQ	Na H antiporter
GSM99_RS03225	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GSM99_RS03230	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GSM99_RS03240	ENOG4108IJ0	Aspartate ammonia-lyase
GSM99_RS03245	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GSM99_RS03250	ENOG4108SIC	Transcriptional regulator
GSM99_RS03260	ENOG4105ZEG	Suppressor protein
GSM99_RS03265	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
GSM99_RS03290	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
GSM99_RS03295	ENOG4105WQV	ferredoxin-like protein
GSM99_RS03300	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GSM99_RS03305	ENOG4105C10	Electron transfer flavoprotein
GSM99_RS03310	ENOG4105CV7	Electron transfer flavoprotein
GSM99_RS03315	ENOG4105C1G	acyl-Coa dehydrogenase
GSM99_RS03320	ENOG4105CY2	Citrate transporter
GSM99_RS03325	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
GSM99_RS03335	ENOG4105CIZ	coA-substrate-specific enzyme activase
GSM99_RS03345	ENOG4105CEY	Amp-dependent synthetase and ligase
GSM99_RS03350	ENOG4105C54	Major Facilitator superfamily
GSM99_RS03355	ENOG4105WQV	ferredoxin-like protein
GSM99_RS03360	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GSM99_RS03380	ENOG4105C1G	acyl-Coa dehydrogenase
GSM99_RS03385	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GSM99_RS03390	ENOG4105CEY	Amp-dependent synthetase and ligase
GSM99_RS03395	ENOG4106YT9	Enoyl-CoA hydratase
GSM99_RS03405	ENOG4108XNW	Transcriptional activatory protein CaiF
GSM99_RS03410	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GSM99_RS03415	ENOG4108M1A	Chitin-binding protein
GSM99_RS03470	ENOG4105DEQ	transcriptional regulator
GSM99_RS03475	ENOG4105Y3E	Modulates RecA activity (By similarity)
GSM99_RS03495	ENOG4108UR8	BAX protein
GSM99_RS03500	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GSM99_RS03515	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS03525	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GSM99_RS03535	ENOG4105S10	periplasmic binding protein
GSM99_RS03540	ENOG4105EHG	Permease protein
GSM99_RS03545	ENOG4105E0A	ABC, transporter
GSM99_RS03550	ENOG4108BSC	Methyltransferase
GSM99_RS03555	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GSM99_RS03605	ENOG4108TN6	type iii secretion
GSM99_RS03615	ENOG41075IY	surface presentation of antigens protein SpaP
GSM99_RS03640	ENOG4108JIR	Flagellum-specific ATP synthase
GSM99_RS03650	ENOG4108HR8	type iii secretion
GSM99_RS03655	ENOG4108N8R	Invasion protein
GSM99_RS03660	ENOG4105K44	type iii secretion
GSM99_RS03665	ENOG41090HZ	type iii secretion
GSM99_RS03675	ENOG4105Y7Q	type iii secretion
GSM99_RS03685	ENOG4108RBT	type iii secretion
GSM99_RS03705	ENOG4108Z4X	TRANSCRIPTIONal
GSM99_RS03715	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
GSM99_RS03720	ENOG4105BZS	acriflavin resistance protein
GSM99_RS03725	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
GSM99_RS03750	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
GSM99_RS03755	ENOG4105KNY	Microcompartments protein
GSM99_RS03760	ENOG4105F1A	Pyruvate formate-lyase
GSM99_RS03765	ENOG4105C6N	Formate acetyltransferase
GSM99_RS03780	ENOG4108EKI	Dehydrogenase
GSM99_RS03785	ENOG4105KNY	Microcompartments protein
GSM99_RS03790	ENOG4105KNY	Microcompartments protein
GSM99_RS03795	ENOG4105KNY	Microcompartments protein
GSM99_RS03830	ENOG4108WDE	Fimbrial protein
GSM99_RS03835	ENOG4108AF8	Chaperone
GSM99_RS03845	ENOG4108SQA	Fimbrial
GSM99_RS03855	ENOG4105ZUU	Transcriptional regulator
GSM99_RS03860	ENOG4107RUE	extracellular solute-binding protein family 1
GSM99_RS03865	ENOG4105D38	putrescine abc transporter
GSM99_RS03870	ENOG4105F38	ABC transporter, permease
GSM99_RS03885	ENOG4106611	bacteriocin immunity
GSM99_RS03890	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GSM99_RS03895	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
GSM99_RS03900	ENOG4105CDU	Replicative dna helicase
GSM99_RS03905	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GSM99_RS03910	ENOG4105CGF	Aromatic amino acid aminotransferase
GSM99_RS03920	ENOG4105C44	Serine transporter
GSM99_RS03930	ENOG4108UUM	single-stranded DNA-binding protein
GSM99_RS03935	ENOG4105MYN	Zinc uptake regulation protein
GSM99_RS03950	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GSM99_RS03955	ENOG41080IJ	Diacylglycerol kinase
GSM99_RS03960	ENOG4105E55	glycerol-3-phosphate acyltransferase
GSM99_RS03965	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GSM99_RS03970	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GSM99_RS03975	ENOG4107QP8	phosphohexose isomerase
GSM99_RS04000	ENOG41069M3	Transcriptional regulator
GSM99_RS04005	ENOG4105C01	Dihydroxy-acid dehydratase
GSM99_RS04010	ENOG4108UHU	Aldolase
GSM99_RS04020	ENOG4108I9X	Isocitrate lyase
GSM99_RS04025	ENOG4107QP3	malate synthase g
GSM99_RS04030	ENOG4105CVG	Homoserine O-transsuccinylase
GSM99_RS04040	ENOG4105WPN	DNA integration recombination invertion protein
GSM99_RS04075	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GSM99_RS04080	ENOG4105C12	Phosphoribosylglycinamide synthetase
GSM99_RS04085	ENOG4108T8B	Protein of unknown function (DUF1481)
GSM99_RS04090	ENOG4105K70	DNA-binding protein
GSM99_RS04095	ENOG4105R2J	Conserved Protein
GSM99_RS04100	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GSM99_RS04105	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GSM99_RS04110	ENOG4105E09	nadh pyrophosphatase
GSM99_RS04120	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GSM99_RS04125	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GSM99_RS04130	ENOG4105D06	uba thif-type nad fad binding protein
GSM99_RS04135	ENOG4105WHD	thiamine biosynthesis protein ThiS
GSM99_RS04145	ENOG4105D41	biosynthesis protein thiH
GSM99_RS04150	ENOG4105DNE	Transposase
GSM99_RS04155	ENOG4107BJW	polysaccharide deacetylase
GSM99_RS04160	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSM99_RS04170	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GSM99_RS04175	ENOG4108VZM	50s ribosomal protein L10
GSM99_RS04180	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GSM99_RS04185	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GSM99_RS04190	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GSM99_RS04195	ENOG4105PM1	preprotein translocase subunit SecE
GSM99_RS04200	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GSM99_RS04205	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GSM99_RS04210	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GSM99_RS04215	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GSM99_RS04225	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GSM99_RS04230	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GSM99_RS04235	ENOG4105WWK	YheO domain protein
GSM99_RS04250	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GSM99_RS04255	ENOG4105VRX	Protein slyX homolog
GSM99_RS04260	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GSM99_RS04265	ENOG4105VKU	nucleicacid-binding protein
GSM99_RS04275	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GSM99_RS04290	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS04295	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GSM99_RS04315	ENOG4105YP7	UPF0270 protein
GSM99_RS04320	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GSM99_RS04325	ENOG4108UKZ	OsmC family
GSM99_RS04330	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GSM99_RS04335	ENOG4105C8Y	Acetylornithine aminotransferase
GSM99_RS04345	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GSM99_RS04350	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GSM99_RS04355	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GSM99_RS04365	ENOG4105C2M	dna polymerase I
GSM99_RS04370	ENOG4108Z33	Thiol disulfide Interchange Protein
GSM99_RS04375	ENOG4105E27	serine threonine protein kinase
GSM99_RS04380	ENOG4105PC1	Conserved Protein
GSM99_RS04385	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GSM99_RS04390	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
GSM99_RS04395	ENOG4105CG3	alpha amylase, catalytic region
GSM99_RS04400	ENOG4105ETE	Transcriptional regulator (LacI family
GSM99_RS04410	ENOG4105DDR	sarcosine oxidase (Beta subunit)
GSM99_RS04415	ENOG4105DC8	reductase
GSM99_RS04420	ENOG4105D6S	protein involved in catabolism of external DNA
GSM99_RS04430	ENOG4107H3J	ribonuclease
GSM99_RS04435	ENOG4105VSH	4-oxalocrotonate tautomerase
GSM99_RS04455	ENOG4105BZU	Histidine kinase
GSM99_RS04460	ENOG4108JQ7	(ABC) transporter
GSM99_RS04465	ENOG4105C3U	ABC transporter
GSM99_RS04470	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS04475	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS04480	ENOG4105DEF	Extracellular solute-binding protein, family 5
GSM99_RS04495	ENOG4105R2A	(LipO)protein
GSM99_RS04505	ENOG4105JKW	Valine--pyruvate aminotransferase
GSM99_RS04510	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GSM99_RS04515	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GSM99_RS04520	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GSM99_RS04540	ENOG4105D99	atp gtp-binding protein
GSM99_RS04545	ENOG4105EN6	Membrane
GSM99_RS04550	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GSM99_RS04555	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GSM99_RS04560	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GSM99_RS04565	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GSM99_RS04570	ENOG4105CB5	ATP-dependent DNA helicase recG
GSM99_RS04575	ENOG4105D6U	Sodium Glutamate Symporter
GSM99_RS04580	ENOG4105C2W	permease
GSM99_RS04585	ENOG4105JV1	AsmA family
GSM99_RS04595	ENOG4105FE9	pseudouridine synthase
GSM99_RS04600	ENOG4105SUU	thioesterase domain
GSM99_RS04605	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GSM99_RS04635	ENOG4105D4P	Coproporphyrinogen iii oxidase
GSM99_RS04640	ENOG4107Y60	(LipO)protein
GSM99_RS04650	ENOG4106B0W	Curli production assembly transport component CsgG
GSM99_RS04655	ENOG4105BZM	domain protein
GSM99_RS04660	ENOG4108RRZ	Transcription elongation factor GreB
GSM99_RS04665	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GSM99_RS04670	ENOG4105E0F	Histidine kinase
GSM99_RS04675	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
GSM99_RS04680	ENOG4105C8U	phosphate abc transporter
GSM99_RS04685	ENOG4105E2Z	phosphate ABC transporter (Permease
GSM99_RS04695	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GSM99_RS04700	ENOG4105CT1	(ABC) transporter
GSM99_RS04705	ENOG4105EAD	ABC transporter
GSM99_RS04715	ENOG4105VTW	prevent-host-death family
GSM99_RS04720	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
GSM99_RS04725	ENOG4105C7N	Xanthine uracil vitamin C permease
GSM99_RS04730	ENOG4105N0V	mono-oxygenase ydhR
GSM99_RS04735	ENOG4105D9U	N-acetyltransferase
GSM99_RS04745	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GSM99_RS04755	ENOG4105XFK	Ferrous iron transport protein A
GSM99_RS04765	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
GSM99_RS04780	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GSM99_RS04785	ENOG4105MJ2	Competence protein
GSM99_RS04790	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GSM99_RS04795	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GSM99_RS04800	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GSM99_RS04805	ENOG4105E98	transcriptional regulator DeoR family
GSM99_RS04810	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GSM99_RS04815	ENOG4105K78	MarR family Transcriptional regulator
GSM99_RS04820	ENOG4105SYT	Methylenetetrahydrofolate reductase
GSM99_RS04835	ENOG4105ETE	Transcriptional regulator (LacI family
GSM99_RS04850	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
GSM99_RS04860	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GSM99_RS04880	ENOG4108S9F	abc transporter, atp-binding protein
GSM99_RS04890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS04895	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS04900	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
GSM99_RS04905	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GSM99_RS04940	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GSM99_RS04950	ENOG4105E6M	Sulphatase-modifying factor protein
GSM99_RS04975	ENOG410901P	UPF0249 protein
GSM99_RS04980	ENOG4105F8D	glycoside hydrolase family 4
GSM99_RS04985	ENOG4105EZV	Transcriptional regulator
GSM99_RS04990	ENOG4105VCP	PTS System
GSM99_RS04995	ENOG4105CK1	PTS System
GSM99_RS05000	ENOG4105VZJ	PTS System
GSM99_RS05010	ENOG4105DHS	permease protein
GSM99_RS05015	ENOG4105CM4	permease protein
GSM99_RS05020	ENOG4108IPW	abc transporter atp-binding protein
GSM99_RS05035	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
GSM99_RS05045	ENOG4107QY8	reductase
GSM99_RS05050	ENOG4105QAX	Iron-sulfur
GSM99_RS05055	ENOG4107KGK	dmso reductase anchor subunit
GSM99_RS05060	ENOG4108NEM	leader-binding protein dmsD
GSM99_RS05065	ENOG4108JUA	Transcriptional regulator
GSM99_RS05080	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
GSM99_RS05095	ENOG4105EAA	nucleoside
GSM99_RS05100	ENOG4105KT7	mgtC SapB transporter
GSM99_RS05130	ENOG4105QEK	Transcriptional regulator
GSM99_RS05135	ENOG4108R66	Conserved Protein
GSM99_RS05140	ENOG4107RJ1	sodium solute
GSM99_RS05150	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GSM99_RS05155	ENOG4108QGT	oligogalacturonate-specific porin
GSM99_RS05160	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GSM99_RS05165	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GSM99_RS05170	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GSM99_RS05175	ENOG4108MG3	formate dehydrogenase
GSM99_RS05180	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GSM99_RS05185	ENOG4105C8J	)-transporter
GSM99_RS05195	ENOG4105CI1	PTS System
GSM99_RS05205	ENOG4105N0E	Protein of unknown function (DUF2543)
GSM99_RS05210	ENOG4105D3G	Pseudouridine synthase
GSM99_RS05225	ENOG4105N1F	Hnh endonuclease
GSM99_RS05255	ENOG4108M6U	Universal stress protein A
GSM99_RS05260	ENOG4108V6B	universal stress protein B
GSM99_RS05265	ENOG4105CJ3	phosphate transporter
GSM99_RS05270	ENOG4105CBX	hi0933 family
GSM99_RS05275	ENOG4105C2I	pirin domain protein
GSM99_RS05280	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GSM99_RS05285	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GSM99_RS05290	ENOG4105VEJ	Heat shock protein
GSM99_RS05295	ENOG4105DQY	intracellular growth attenuator
GSM99_RS05300	ENOG4107RK2	ADP-ribose diphosphatase NudE
GSM99_RS05305	ENOG4108JQC	penicillin-binding protein 1A
GSM99_RS05325	ENOG4105E4G	Type IV pilus
GSM99_RS05330	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GSM99_RS05335	ENOG4105D49	3-dehydroquinate synthase
GSM99_RS05350	ENOG4105DJV	ribulose-phosphate 3-epimerase
GSM99_RS05355	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GSM99_RS05360	ENOG4105C31	Tryptophanyl-tRNA synthetase
GSM99_RS05365	ENOG4108RPX	mosc domain containing protein
GSM99_RS05370	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GSM99_RS05375	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GSM99_RS05380	ENOG41062QD	Membrane
GSM99_RS05385	ENOG4107QN1	sodium solute
GSM99_RS05420	ENOG4107EJG	GntR family transcriptional regulator
GSM99_RS05425	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GSM99_RS05430	ENOG4108RVA	ribokinase
GSM99_RS05435	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
GSM99_RS05440	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GSM99_RS05445	ENOG4105CU9	asparagine synthetase A
GSM99_RS05450	ENOG4108VVK	transcriptional Regulator, AsnC
GSM99_RS05455	ENOG4105QTB	Flavodoxin
GSM99_RS05460	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GSM99_RS05465	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GSM99_RS05470	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
GSM99_RS05475	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GSM99_RS05480	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GSM99_RS05510	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GSM99_RS05515	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GSM99_RS05520	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GSM99_RS05635	ENOG4105H4F	exported protein
GSM99_RS05640	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GSM99_RS05650	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GSM99_RS05665	ENOG4107QZ7	Cellulose synthase catalytic subunit
GSM99_RS05675	ENOG4105EJG	cellulose synthase
GSM99_RS05685	ENOG4105BZU	Histidine kinase
GSM99_RS05695	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
GSM99_RS05705	ENOG4107T7U	Sulfatase
GSM99_RS05710	ENOG4105EM7	Selenocysteine-specific translation elongation factor
GSM99_RS05715	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
GSM99_RS05720	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
GSM99_RS05725	ENOG4108MG3	formate dehydrogenase
GSM99_RS05730	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GSM99_RS05740	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GSM99_RS05765	ENOG4106P55	Transcriptional regulator
GSM99_RS05785	ENOG41067XB	TonB family
GSM99_RS05790	ENOG4108UQ5	membrane protein YcdZ
GSM99_RS05800	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GSM99_RS05805	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GSM99_RS05810	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GSM99_RS05815	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GSM99_RS05820	ENOG4105VG0	50S ribosomal protein l34
GSM99_RS05830	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GSM99_RS05835	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GSM99_RS05845	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GSM99_RS05855	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GSM99_RS05880	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GSM99_RS05885	ENOG4105DSJ	YicC domain protein
GSM99_RS05890	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GSM99_RS05895	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GSM99_RS05900	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GSM99_RS05905	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GSM99_RS05910	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GSM99_RS05915	ENOG4105W5Q	DNA repair protein (RadC
GSM99_RS05920	ENOG4105KDC	50s ribosomal protein l28
GSM99_RS05925	ENOG4105W0E	50S ribosomal protein L33
GSM99_RS05930	ENOG4107SBE	Glycosyl transferase (Group 1
GSM99_RS05940	ENOG4107QPH	glycogen) synthase
GSM99_RS05950	ENOG4108FRV	O-antigen ligase
GSM99_RS05955	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GSM99_RS05960	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GSM99_RS05970	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GSM99_RS05975	ENOG4107RA4	Glycosyl transferase (Group 1
GSM99_RS05980	ENOG4107RJ7	Glycosyl transferase (Group 1
GSM99_RS05985	ENOG4105DKP	glycosyl transferase, family 9
GSM99_RS05995	ENOG4105DKP	glycosyl transferase, family 9
GSM99_RS06000	ENOG4105D16	lipopolysaccharide heptosyltransferase i
GSM99_RS06005	ENOG4105XA0	heptosyltransferase ii
GSM99_RS06010	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GSM99_RS06020	ENOG4105CPQ	Dehydrogenase
GSM99_RS06025	ENOG4105PXI	polysaccharide deacetylase
GSM99_RS06030	ENOG41063SB	peptidase
GSM99_RS06035	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GSM99_RS06040	ENOG4107YZP	Rhodanese domain protein
GSM99_RS06045	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GSM99_RS06055	ENOG4105D7W	serine acetyltransferase
GSM99_RS06060	ENOG4105D7W	serine acetyltransferase
GSM99_RS06065	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GSM99_RS06105	ENOG4107RA4	Glycosyl transferase (Group 1
GSM99_RS06135	ENOG4105E0F	Histidine kinase
GSM99_RS06140	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GSM99_RS06145	ENOG4105FMW	periplasmic
GSM99_RS06150	ENOG4108J6E	Pfam:Phage_integr_N
GSM99_RS06190	ENOG4105DFE	Dna adenine methylase
GSM99_RS06200	ENOG4105VZ1	Replication Protein
GSM99_RS06215	ENOG4105ED4	portal protein
GSM99_RS06300	ENOG4105PTU	response to oxidative stress
GSM99_RS06340	ENOG4105ZTC	transcriptional activator, Ogr delta
GSM99_RS06345	ENOG4105UPP	uncharacterized protein ydcA
GSM99_RS06355	ENOG4107J0A	lipopolysaccharide biosynthetic process
GSM99_RS06365	ENOG4105CHR	reductase
GSM99_RS06370	ENOG4105CTQ	phosphohexokinase
GSM99_RS06375	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GSM99_RS06380	ENOG4105CP7	Triose-phosphate isomerase
GSM99_RS06385	ENOG4105EBK	exported protein
GSM99_RS06390	ENOG4108VTS	Membrane
GSM99_RS06395	ENOG4105DP0	ferredoxin-NADP reductase
GSM99_RS06400	ENOG4105E5M	Multidrug resistance protein D
GSM99_RS06405	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GSM99_RS06410	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GSM99_RS06415	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GSM99_RS06420	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GSM99_RS06425	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GSM99_RS06430	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GSM99_RS06435	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GSM99_RS06440	ENOG41063M6	Cell Division Protein
GSM99_RS06445	ENOG4105ETE	Transcriptional regulator (LacI family
GSM99_RS06450	ENOG4105C25	Primosomal protein n'
GSM99_RS06455	ENOG41082DI	50s ribosomal protein l31
GSM99_RS06460	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GSM99_RS06465	ENOG4105C28	cystathionine
GSM99_RS06470	ENOG4105CFH	Aspartokinase
GSM99_RS06475	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GSM99_RS06480	ENOG4105K64	Glycosyl transferase, family 2
GSM99_RS06485	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GSM99_RS06490	ENOG4105CSH	Transporter
GSM99_RS06495	ENOG4107R11	Transcriptional regulator
GSM99_RS06515	ENOG4105C7K	acetolactate synthase
GSM99_RS06520	ENOG4105CWC	Acetylornithine deacetylase
GSM99_RS06525	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GSM99_RS06530	ENOG4105CAS	nag kinase
GSM99_RS06535	ENOG4105CDH	Citrulline--aspartate ligase
GSM99_RS06540	ENOG4105CH7	arginosuccinase
GSM99_RS06560	ENOG4108Y73	Membrane
GSM99_RS06565	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GSM99_RS06570	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GSM99_RS06575	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GSM99_RS06610	ENOG4105D4A	Cell wall formation (By similarity)
GSM99_RS06615	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GSM99_RS06620	ENOG4105CS9	pantothenic acid kinase
GSM99_RS06645	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GSM99_RS06650	ENOG4105W53	bacterioferritin-associated ferredoxin
GSM99_RS06665	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GSM99_RS06670	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GSM99_RS06675	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GSM99_RS06680	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSM99_RS06685	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GSM99_RS06690	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GSM99_RS06695	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GSM99_RS06700	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GSM99_RS06705	ENOG41083MP	50s ribosomal protein l29
GSM99_RS06710	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GSM99_RS06715	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GSM99_RS06720	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GSM99_RS06725	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSM99_RS06730	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GSM99_RS06735	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GSM99_RS06740	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GSM99_RS06745	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GSM99_RS06750	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GSM99_RS06755	ENOG4105VPB	50S ribosomal protein L30
GSM99_RS06760	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GSM99_RS06765	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GSM99_RS06770	ENOG41067V7	50S ribosomal protein L36
GSM99_RS06775	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GSM99_RS06780	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GSM99_RS06785	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GSM99_RS06795	ENOG4108ZT0	50S ribosomal protein l17
GSM99_RS06800	ENOG4105W1Y	Transcriptional regulator
GSM99_RS06805	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
GSM99_RS06810	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GSM99_RS06815	ENOG4105C1A	potassium transporter peripheral membrane
GSM99_RS06820	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GSM99_RS06825	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GSM99_RS06830	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GSM99_RS06835	ENOG4105C79	DNA protecting protein DprA
GSM99_RS06840	ENOG4108WI1	Dna topoisomerase
GSM99_RS06845	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GSM99_RS06850	ENOG4105E2X	shikimate dehydrogenase
GSM99_RS06855	ENOG4105SG3	Protein of unknown function (DUF1488)
GSM99_RS06860	ENOG4108Z0R	Transferase
GSM99_RS06895	ENOG4105CVI	Transcriptional regulator
GSM99_RS06900	ENOG4108WFC	UPF0438 protein yifE
GSM99_RS06905	ENOG4105C0P	Mg chelatase subunit ChlI
GSM99_RS06920	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GSM99_RS06925	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GSM99_RS06930	ENOG4105C01	Dihydroxy-acid dehydratase
GSM99_RS06935	ENOG4105C7B	Threonine dehydratase
GSM99_RS06940	ENOG4105EMY	transcriptional regulator
GSM99_RS06945	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GSM99_RS06950	ENOG4105C4R	Atp-dependent dna helicase
GSM99_RS06955	ENOG4105C9X	ppx gppa phosphatase
GSM99_RS06960	ENOG4105C1J	atp-dependent rna helicase
GSM99_RS06965	ENOG4105K63	Thioredoxin
GSM99_RS06975	ENOG4105ESV	Glycosyl transferase, family 4
GSM99_RS06980	ENOG4105SFE	lipopolysaccharide biosynthesis protein
GSM99_RS06985	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GSM99_RS06990	ENOG4108IJ1	Dehydrogenase
GSM99_RS06995	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GSM99_RS07000	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GSM99_RS07010	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GSM99_RS07015	ENOG4105EGZ	biosynthesis protein
GSM99_RS07020	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
GSM99_RS07025	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
GSM99_RS07030	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GSM99_RS07065	ENOG4105ECF	c-methyltransferase
GSM99_RS07075	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GSM99_RS07080	ENOG4107T0K	Adenylate cyclase
GSM99_RS07085	ENOG4105XQ6	frataxin-like protein
GSM99_RS07090	ENOG4105S7Z	(LipO)protein
GSM99_RS07095	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GSM99_RS07105	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSM99_RS07110	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GSM99_RS07125	ENOG4105FR1	rard protein
GSM99_RS07130	ENOG4108VUY	thioesterase Superfamily protein
GSM99_RS07135	ENOG4105HDD	phospholipase
GSM99_RS07145	ENOG4108EUD	Lysophospholipase
GSM99_RS07150	ENOG4105DQF	Hydrolase
GSM99_RS07155	ENOG4105EGS	Mechanosensitive ion channel
GSM99_RS07160	ENOG4105DJ4	phosphatidylserine decarboxylase
GSM99_RS07165	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GSM99_RS07170	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GSM99_RS07190	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GSM99_RS07195	ENOG4105K8N	protein family UPF0079, ATPase
GSM99_RS07200	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GSM99_RS07210	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GSM99_RS07215	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GSM99_RS07220	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GSM99_RS07225	ENOG4107QJR	hflk protein
GSM99_RS07235	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GSM99_RS07240	ENOG4105KPV	Transcriptional regulator
GSM99_RS07245	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GSM99_RS07250	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GSM99_RS07255	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GSM99_RS07260	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GSM99_RS07265	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GSM99_RS07270	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GSM99_RS07285	ENOG4105NRA	50s ribosomal protein l31 type b
GSM99_RS07290	ENOG4105YK5	50S ribosomal protein L36
GSM99_RS07295	ENOG4108MEK	Metal-binding protein YodA
GSM99_RS07300	ENOG4105C26	Dehydrogenase
GSM99_RS07305	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GSM99_RS07310	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GSM99_RS07315	ENOG4108UUE	Transcriptional regulator
GSM99_RS07320	ENOG41061GZ	Protein of unknown function (DUF1107)
GSM99_RS07325	ENOG4105C37	(CBS) domain
GSM99_RS07330	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GSM99_RS07335	ENOG4105CFU	surface antigen
GSM99_RS07340	ENOG4105MA0	exported protein
GSM99_RS07345	ENOG4108ZHD	aig2 family
GSM99_RS07355	ENOG4105F0N	pyrophosphate phospho-hydrolase
GSM99_RS07360	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GSM99_RS07365	ENOG4105DFU	Cell wall formation (By similarity)
GSM99_RS07370	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GSM99_RS07375	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GSM99_RS07380	ENOG4105HVQ	Regulatory factor of maltose metabolism
GSM99_RS07395	ENOG4105EAH	synthase
GSM99_RS07400	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GSM99_RS07405	ENOG4105K46	50S ribosomal protein l27
GSM99_RS07410	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSM99_RS07415	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GSM99_RS07420	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GSM99_RS07425	ENOG4105HBR	Rna-binding protein
GSM99_RS07430	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GSM99_RS07435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GSM99_RS07440	ENOG4105EEI	dihydropteroate synthase
GSM99_RS07445	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GSM99_RS07465	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GSM99_RS07470	ENOG4105CHV	Transcription elongation factor NusA
GSM99_RS07480	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GSM99_RS07485	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GSM99_RS07490	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GSM99_RS07495	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GSM99_RS07505	ENOG4105C1J	atp-dependent rna helicase
GSM99_RS07510	ENOG4108NEV	two component transcriptional regulator, LytTR family
GSM99_RS07515	ENOG4108HRK	Histidine kinase
GSM99_RS07520	ENOG4107V40	secretion protein, HlyD family
GSM99_RS07535	ENOG4106RZ4	Peptidase U32
GSM99_RS07540	ENOG4105CFP	Peptidase U32
GSM99_RS07545	ENOG4105XPQ	lipid carrier protein
GSM99_RS07550	ENOG4108YYD	acetyltransferase
GSM99_RS07555	ENOG41082IR	Excinuclease ABC C subunit domain protein
GSM99_RS07560	ENOG4105ZY9	UPF0379 protein ybiM
GSM99_RS07580	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GSM99_RS07590	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GSM99_RS07595	ENOG4105KME	endoribonuclease L-psp
GSM99_RS07600	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GSM99_RS07605	ENOG4105CXT	aspartate transcarbamylase
GSM99_RS07610	ENOG4105DBV	ornithine carbamoyltransferase
GSM99_RS07615	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
GSM99_RS07620	ENOG4105EUB	pirin domain protein
GSM99_RS07625	ENOG4105VYH	
GSM99_RS07630	ENOG4108MJ3	acetyltransferase
GSM99_RS07635	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GSM99_RS07640	ENOG4105MYG	DNA polymerase iii, chi subunit
GSM99_RS07645	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GSM99_RS07650	ENOG4108M8S	permease YjgP YjgQ family protein
GSM99_RS07655	ENOG4108K5H	permease YjgP YjgQ family protein
GSM99_RS07660	ENOG4107R6D	beta-lactam binding protein AmpH
GSM99_RS07720	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GSM99_RS07730	ENOG4105C5E	polysaccharide biosynthesis protein
GSM99_RS07745	ENOG4107SJB	teichoic acid biosynthesis
GSM99_RS07750	ENOG4105ER6	polysaccharide biosynthesis protein
GSM99_RS07755	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
GSM99_RS07845	ENOG4105CW0	outer membrane usher protein
GSM99_RS07855	ENOG4106UCC	Fimbrial protein
GSM99_RS07860	ENOG4108JUB	Transcriptional regulator
GSM99_RS07865	ENOG4107RCH	Diaminopropionate ammonia-lyase
GSM99_RS07880	ENOG4105DJB	Major Facilitator Superfamily
GSM99_RS07885	ENOG4108S2Y	peptide Chain Release factor
GSM99_RS07895	ENOG4107FB0	transcriptional regulator DeoR family
GSM99_RS07900	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GSM99_RS07905	ENOG4108RVA	ribokinase
GSM99_RS07910	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GSM99_RS07920	ENOG4105HX0	Transcriptional regulator
GSM99_RS07935	ENOG4105DBV	ornithine carbamoyltransferase
GSM99_RS07940	ENOG4105C5B	carbamate kinase
GSM99_RS07945	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GSM99_RS07955	ENOG4105C7K	acetolactate synthase
GSM99_RS07960	ENOG4105M71	acetolactate synthase 1 regulatory subunit
GSM99_RS07985	ENOG4105C7N	Xanthine uracil vitamin C permease
GSM99_RS07995	ENOG4105EEQ	Na H antiporter
GSM99_RS08000	ENOG4105EMK	carboxylate amino acid amine transporter
GSM99_RS08005	ENOG4105DZ2	Transcriptional regulator
GSM99_RS08010	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GSM99_RS08020	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
GSM99_RS08025	ENOG4108I5U	Uridine phosphorylase
GSM99_RS08035	ENOG4108KF1	Membrane
GSM99_RS08040	ENOG4105CGY	Dna recombination protein
GSM99_RS08045	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GSM99_RS08050	ENOG4105JC1	sterol-binding domain protein
GSM99_RS08060	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GSM99_RS08065	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GSM99_RS08070	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GSM99_RS08075	ENOG4105MDZ	Transcriptional activator rfaH
GSM99_RS08080	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
GSM99_RS08085	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GSM99_RS08090	ENOG4107QK7	reductase
GSM99_RS08095	ENOG4105CHU	acetyl-coa acetyltransferase
GSM99_RS08100	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GSM99_RS08105	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
GSM99_RS08110	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GSM99_RS08115	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GSM99_RS08120	ENOG4108RR8	protoporphyrinogen oxidase
GSM99_RS08150	ENOG4105C5A	transporter
GSM99_RS08155	ENOG4105E7W	lamb ycsf family protein
GSM99_RS08160	ENOG4105CFM	UPF0317 protein
GSM99_RS08165	ENOG4105P4J	Allophanate hydrolase, subunit 1
GSM99_RS08170	ENOG4108JIK	carboxylase
GSM99_RS08175	ENOG4105HF0	Membrane
GSM99_RS08190	ENOG4105HEI	LysR family (Transcriptional regulator
GSM99_RS08195	ENOG4105WH1	Two component transcriptional regulator luxr family
GSM99_RS08200	ENOG4105BZU	Histidine kinase
GSM99_RS08205	ENOG4105DQQ	Major facilitator superfamily MFS_1
GSM99_RS08210	ENOG4105CRU	nitrate reductase, alpha subunit
GSM99_RS08215	ENOG4108IUE	nitrate reductase beta subunit
GSM99_RS08220	ENOG4105R3A	Nitrate reductase
GSM99_RS08225	ENOG41076YT	nitrate reductase, gamma subunit
GSM99_RS08230	ENOG4105CHJ	isochorismatase hydrolase
GSM99_RS08240	ENOG4105DIJ	Phosphoethanolamine transferase
GSM99_RS08250	ENOG4105CI1	PTS System
GSM99_RS08260	ENOG4108Q3X	Transcriptional regulator
GSM99_RS08295	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GSM99_RS08300	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GSM99_RS08315	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GSM99_RS08340	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GSM99_RS08345	ENOG4105CXY	transporter
GSM99_RS08350	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GSM99_RS08360	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GSM99_RS08365	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GSM99_RS08375	ENOG4105EX9	Membrane
GSM99_RS08380	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GSM99_RS08385	ENOG4105C59	p-type ATPase
GSM99_RS08390	ENOG4107FS9	Membrane
GSM99_RS08400	ENOG4105MG3	Membrane
GSM99_RS08405	ENOG4106H78	methyltransferase
GSM99_RS08410	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GSM99_RS08415	ENOG4105CAK	Cell division ATP-binding protein ftsE
GSM99_RS08420	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GSM99_RS08430	ENOG4105BZW	Glycerate kinase
GSM99_RS08435	ENOG4105U59	-acetyltransferase
GSM99_RS08445	ENOG4108INS	Transcriptional regulator
GSM99_RS08455	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GSM99_RS08460	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS08475	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GSM99_RS08485	ENOG4105DJ2	Major Facilitator Superfamily
GSM99_RS08530	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GSM99_RS08535	ENOG4108IA2	Sodium pantothenate symporter
GSM99_RS08540	ENOG4105RG0	Membrane
GSM99_RS08545	ENOG4105C87	Aminotransferase class I and II
GSM99_RS08550	ENOG4105C44	Serine transporter
GSM99_RS08555	ENOG4105FKN	transcriptional regulator, AsnC family
GSM99_RS08560	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GSM99_RS08565	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GSM99_RS08570	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GSM99_RS08575	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GSM99_RS08580	ENOG4105DFF	Rod shape-determining protein mreb
GSM99_RS08585	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GSM99_RS08590	ENOG4105VQ7	Rod shape-determining protein MreD
GSM99_RS08595	ENOG4108Z03	MAF-like protein
GSM99_RS08600	ENOG4105C03	ribonuclease
GSM99_RS08605	ENOG4105QD6	exported protein
GSM99_RS08615	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GSM99_RS08620	ENOG4105GGE	ribonuclease
GSM99_RS08630	ENOG4105N42	UPF0307 protein
GSM99_RS08640	ENOG4105NXH	GreA GreB family elongation factor
GSM99_RS08645	ENOG41080Z8	PHOSPHOCARRIER protein
GSM99_RS08655	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GSM99_RS08660	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GSM99_RS08675	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GSM99_RS08680	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
GSM99_RS08690	ENOG4105C2X	Arabinose 5-phosphate isomerase
GSM99_RS08715	ENOG4105E3I	toluene tolerance
GSM99_RS08725	ENOG4105VFK	BolA family
GSM99_RS08730	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GSM99_RS08750	ENOG4105C0H	protease
GSM99_RS08755	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
GSM99_RS08760	ENOG4105D6Z	AFG1 family ATPase
GSM99_RS08765	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GSM99_RS08770	ENOG4108UJD	30S ribosomal protein S9
GSM99_RS08775	ENOG4107MKT	Stringent starvation protein a
GSM99_RS08780	ENOG4105KB2	stringent starvation protein b
GSM99_RS08785	ENOG4105CH2	amidohydrolase
GSM99_RS08795	ENOG4105BZ8	glutamate synthase
GSM99_RS08800	ENOG4105CBC	glutamate synthase
GSM99_RS08805	ENOG4105BZU	Histidine kinase
GSM99_RS08810	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GSM99_RS08820	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
GSM99_RS08830	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GSM99_RS08835	ENOG4105KI2	Urea amidohydrolase subunit beta
GSM99_RS08845	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
GSM99_RS08850	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GSM99_RS08855	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GSM99_RS08860	ENOG4105W4M	Transport-associated protein
GSM99_RS08865	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GSM99_RS08870	ENOG41082RQ	UPF0102 protein
GSM99_RS08880	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GSM99_RS08890	ENOG4108CNN	domain protein
GSM99_RS08895	ENOG4105CWB	LysR family transcriptional Regulator
GSM99_RS08900	ENOG4108VBZ	doxx family
GSM99_RS08915	ENOG4105NE1	Conserved Protein
GSM99_RS08920	ENOG4106W5V	Membrane
GSM99_RS08925	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GSM99_RS08930	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GSM99_RS08945	ENOG4105CQ0	ABC transporter
GSM99_RS08950	ENOG4105PE1	Receptor
GSM99_RS08960	ENOG4108SF5	RNA Polymerase
GSM99_RS08970	ENOG4105C5H	ABC transporter
GSM99_RS08975	ENOG4107SC1	transglycosylase
GSM99_RS08980	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GSM99_RS08985	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GSM99_RS08990	ENOG4105CVJ	phosphoglycerate mutase
GSM99_RS08995	ENOG4105UEI	Transcriptional Regulator AraC Family
GSM99_RS09000	ENOG4108RH0	Crea protein
GSM99_RS09005	ENOG41065U4	response regulator
GSM99_RS09015	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GSM99_RS09035	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GSM99_RS09050	ENOG4105CFG	Acts as a chaperone (By similarity)
GSM99_RS09055	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GSM99_RS09065	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GSM99_RS09070	ENOG41063Z6	transcriptional regulator, lysR family
GSM99_RS09075	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GSM99_RS09085	ENOG4105DTN	riboflavin biosynthesis protein ribF
GSM99_RS09090	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GSM99_RS09095	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GSM99_RS09100	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GSM99_RS09110	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GSM99_RS09115	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GSM99_RS09130	ENOG4105TNG	K13735 adhesin invasin
GSM99_RS09135	ENOG4105CV8	reductase
GSM99_RS09140	ENOG4108I6A	alcohol dehydrogenase
GSM99_RS09145	ENOG4108I0C	methyltransferase
GSM99_RS09150	ENOG4108K81	inner membrane protein YghB
GSM99_RS09155	ENOG4105C28	cystathionine
GSM99_RS09160	ENOG4105CWK	Biopolymer transport protein, ExbB
GSM99_RS09165	ENOG4108ZZF	transport protein (ExbD)
GSM99_RS09170	ENOG4105E3S	small subunit
GSM99_RS09175	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GSM99_RS09180	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
GSM99_RS09185	ENOG4105DPX	Hydrogenase, large subunit
GSM99_RS09190	ENOG4108USZ	hydrogenase
GSM99_RS09195	ENOG4108WGS	hydrogenase 2-specific chaperone
GSM99_RS09200	ENOG4107RSS	Hydrogenase accessory protein HypB
GSM99_RS09205	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
GSM99_RS09210	ENOG4105CQS	hydrogenase expression formation protein HypD
GSM99_RS09215	ENOG4105C45	hydrogenase expression formation protein (HypE)
GSM99_RS09220	ENOG41066VF	YeeE YedE family protein
GSM99_RS09225	ENOG4105KSU	Redox protein
GSM99_RS09230	ENOG4105DH7	May be involved in recombination (By similarity)
GSM99_RS09240	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GSM99_RS09245	ENOG41083KI	ribonuclease, T2
GSM99_RS09250	ENOG4107T31	5'-nucleotidase
GSM99_RS09265	ENOG4107RH8	nuclease SbcCD subunit D
GSM99_RS09270	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSM99_RS09285	ENOG4108Y7C	Conserved Protein
GSM99_RS09285	ENOG4108Y7C	Conserved Protein
GSM99_RS09290	ENOG4108NWD	Cytochrome
GSM99_RS09295	ENOG4108393	oxidoreductase Fe-S subunit
GSM99_RS09300	ENOG4105JVW	
GSM99_RS09305	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
GSM99_RS09310	ENOG4108PU5	4fe-4S ferredoxin, iron-sulfur binding domain protein
GSM99_RS09320	ENOG4105D3R	alkyl hydroperoxide reductase
GSM99_RS09325	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GSM99_RS09330	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GSM99_RS09335	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GSM99_RS09340	ENOG4105VIE	preprotein translocase, subunit YajC
GSM99_RS09345	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GSM99_RS09350	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GSM99_RS09355	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GSM99_RS09365	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GSM99_RS09370	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GSM99_RS09375	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GSM99_RS09380	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GSM99_RS09385	ENOG4105ETE	Transcriptional regulator (LacI family
GSM99_RS09390	ENOG4108RVA	ribokinase
GSM99_RS09395	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GSM99_RS09400	ENOG4105CNN	ABC, transporter
GSM99_RS09405	ENOG4105C2J	ABC transporter
GSM99_RS09410	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GSM99_RS09415	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GSM99_RS09420	ENOG4105CTB	Polyprenyl synthetase
GSM99_RS09425	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GSM99_RS09430	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GSM99_RS09440	ENOG4107S0N	DJ-1 family
GSM99_RS09450	ENOG4108VPT	UPF0234 protein
GSM99_RS09455	ENOG4107RDB	Major Facilitator
GSM99_RS09460	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GSM99_RS09465	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GSM99_RS09470	ENOG4105CCU	oxidase (Subunit III)
GSM99_RS09475	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GSM99_RS09480	ENOG4105E2S	oxidase) subunit II
GSM99_RS09485	ENOG4108NFH	Sugar hydrolase
GSM99_RS09490	ENOG4105C1J	atp-dependent rna helicase
GSM99_RS09495	ENOG4105EYM	Major Facilitator superfamily
GSM99_RS09500	ENOG4105IEY	(LipO)protein
GSM99_RS09505	ENOG4105M85	Bola protein
GSM99_RS09510	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GSM99_RS09515	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GSM99_RS09520	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GSM99_RS09525	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GSM99_RS09530	ENOG4105K70	DNA-binding protein
GSM99_RS09535	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GSM99_RS09540	ENOG4105KQC	Competence protein
GSM99_RS09545	ENOG4108TGP	Thioesterase superfamily protein
GSM99_RS09550	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GSM99_RS09555	ENOG4108XM1	transcriptional regulator AsnC family
GSM99_RS09565	ENOG4105BZ1	(ABC) transporter
GSM99_RS09570	ENOG4108YZA	Nitrogen regulatory protein pii
GSM99_RS09575	ENOG4105BZU	Histidine kinase
GSM99_RS09580	ENOG4105C29	acyl-CoA thioesterase
GSM99_RS09590	ENOG4105KF5	hemolysin expression-modulating protein
GSM99_RS09600	ENOG4105BZS	acriflavin resistance protein
GSM99_RS09605	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GSM99_RS09610	ENOG4108IG5	Transcriptional regulator
GSM99_RS09615	ENOG41090EX	DsrE family
GSM99_RS09620	ENOG4105EGS	Mechanosensitive ion channel
GSM99_RS09635	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GSM99_RS09640	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GSM99_RS09645	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GSM99_RS09650	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GSM99_RS09655	ENOG4108M24	von Willebrand factor, type A
GSM99_RS09675	ENOG4105D22	carbon starvation protein
GSM99_RS09680	ENOG4105VCD	cytoplasmic protein
GSM99_RS09685	ENOG4105CKI	cobalamin synthesis protein
GSM99_RS09695	ENOG4105CEE	C4-dicarboxylate transporter
GSM99_RS09700	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GSM99_RS09715	ENOG4105UQX	Mate efflux family protein
GSM99_RS09720	ENOG4105DGA	Diaminopimelate dehydrogenase
GSM99_RS09730	ENOG4105EQN	UPF0261 protein
GSM99_RS09785	ENOG4108ZRK	uncharacterized protein yacC
GSM99_RS09790	ENOG4105E3B	Multicopper oxidase
GSM99_RS09795	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GSM99_RS09800	ENOG41077A9	carbonic anhydrase
GSM99_RS09805	ENOG4105DA5	(ABC) transporter
GSM99_RS09815	ENOG41079KZ	Major Facilitator Superfamily
GSM99_RS09820	ENOG4105R71	cytoplasmic protein
GSM99_RS09825	ENOG4105D0M	Protease HtpX homolog
GSM99_RS09840	ENOG4105QAX	Iron-sulfur
GSM99_RS09855	ENOG4105DBE	peroxidase
GSM99_RS09870	ENOG4105WP5	
GSM99_RS09885	ENOG4106032	Glutathionylspermidine synthase
GSM99_RS09890	ENOG4105W8I	Transcriptional regulator
GSM99_RS09900	ENOG4105BZC	d-serine deaminase
GSM99_RS09910	ENOG4107RCV	ABC transporter, permease
GSM99_RS09915	ENOG4105C4Y	ABC transporter
GSM99_RS09920	ENOG4105CXY	transporter
GSM99_RS09925	ENOG4105BZU	Histidine kinase
GSM99_RS09930	ENOG4108KX4	response regulator
GSM99_RS09935	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GSM99_RS09940	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GSM99_RS09945	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GSM99_RS09955	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GSM99_RS09960	ENOG4105DJ0	Poly(A) Polymerase
GSM99_RS09965	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GSM99_RS09970	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GSM99_RS09975	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GSM99_RS09980	ENOG4105CQ7	ATP-dependent helicase
GSM99_RS09985	ENOG4105BZ4	penicillin-binding protein
GSM99_RS09990	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GSM99_RS09995	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GSM99_RS10005	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GSM99_RS10015	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GSM99_RS10020	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GSM99_RS10025	ENOG4105DXN	mazG family
GSM99_RS10035	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GSM99_RS10040	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GSM99_RS10045	ENOG4105C8P	)-transporter
GSM99_RS10050	ENOG4105E9H	Lytic Murein transglycosylase
GSM99_RS10055	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GSM99_RS10060	ENOG4105D1A	Methyltransferase
GSM99_RS10065	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GSM99_RS10070	ENOG4108JDX	DNA polymerase iii, epsilon subunit
GSM99_RS10100	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GSM99_RS10105	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GSM99_RS10110	ENOG4105BZA	Phosphoglycerate kinase
GSM99_RS10115	ENOG4105D2N	Aldolase
GSM99_RS10120	ENOG4105DUX	Transporter
GSM99_RS10130	ENOG4108V8F	Transcriptional regulator, MarR family
GSM99_RS10135	ENOG4105C94	Transporter
GSM99_RS10150	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GSM99_RS10155	ENOG4105CYB	regulatoR
GSM99_RS10165	ENOG4105E0Y	RtcB Protein
GSM99_RS10170	ENOG4108W9T	type 1 fimbriae regulatory protein
GSM99_RS10175	ENOG4105HMV	Fimbrial protein
GSM99_RS10190	ENOG4106P2F	Pfam:Pili_assembly_C
GSM99_RS10205	ENOG4105H8W	Fimbrial protein
GSM99_RS10220	ENOG4105HMV	Fimbrial protein
GSM99_RS10230	ENOG4106PG1	outer membrane usher protein
GSM99_RS10235	ENOG4108FZ9	Chaperone
GSM99_RS10240	ENOG4105UGQ	Fimbrial
GSM99_RS10250	ENOG4105H8W	Fimbrial protein
GSM99_RS10270	ENOG4105VTS	DnaJ-like, subfamily C
GSM99_RS10280	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GSM99_RS10285	ENOG4105DFG	type I secretion outer membrane protein
GSM99_RS10290	ENOG4107QZV	Type I secretion membrane fusion protein
GSM99_RS10295	ENOG4108JJ6	Type I secretion system ATPase
GSM99_RS10320	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
GSM99_RS10335	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GSM99_RS10340	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GSM99_RS10345	ENOG4105CEN	a g-specific adenine glycosylase
GSM99_RS10355	ENOG41090ED	Protein with unknown function (DUF469)
GSM99_RS10360	ENOG4105CSV	Glutaminase
GSM99_RS10365	ENOG4105K33	Periplasmic Protein
GSM99_RS10375	ENOG4105CSA	Coproporphyrinogen iii oxidase
GSM99_RS10380	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GSM99_RS10385	ENOG4108VIA	integral membrane protein
GSM99_RS10390	ENOG4105II7	pyrroline-5-carboxylate reductase
GSM99_RS10395	ENOG4105DFA	alanine racemase domain protein
GSM99_RS10400	ENOG4105CZX	twitching motility protein
GSM99_RS10405	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GSM99_RS10410	ENOG4108UJU	UPF0301 protein
GSM99_RS10415	ENOG4105D7Z	glutathione synthase
GSM99_RS10420	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GSM99_RS10440	ENOG4105EJC	lysr family transcriptional regulator
GSM99_RS10445	ENOG4105RQF	LysR family Transcriptional regulator
GSM99_RS10450	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GSM99_RS10455	ENOG4107QPN	acyl-Coa dehydrogenase
GSM99_RS10460	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GSM99_RS10465	ENOG4105E7A	Glutamine amidotransferase
GSM99_RS10470	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
GSM99_RS10475	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GSM99_RS10480	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GSM99_RS10485	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GSM99_RS10490	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GSM99_RS10495	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GSM99_RS10500	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GSM99_RS10505	ENOG4105CJ2	(LipO)protein
GSM99_RS10515	ENOG4105VDW	Csbd family
GSM99_RS10525	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GSM99_RS10530	ENOG4105E0K	tonB-dependent siderophore receptor
GSM99_RS10535	ENOG4105CIN	aminoacyl-histidine dipeptidase
GSM99_RS10540	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GSM99_RS10545	ENOG4105V1F	Fermentation respiration switch protein
GSM99_RS10555	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GSM99_RS10560	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GSM99_RS10565	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GSM99_RS10570	ENOG4105CEY	Amp-dependent synthetase and ligase
GSM99_RS10575	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GSM99_RS10580	ENOG4107TH8	cina domain protein
GSM99_RS10585	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GSM99_RS10590	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GSM99_RS10595	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GSM99_RS10625	ENOG4105D9M	gamma-glutamylcysteine synthetase
GSM99_RS10630	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GSM99_RS10640	ENOG4108JU6	CBS domain protein
GSM99_RS10650	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GSM99_RS10655	ENOG4105K5M	30s ribosomal protein S16
GSM99_RS10665	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GSM99_RS10670	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GSM99_RS10675	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GSM99_RS10680	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GSM99_RS10690	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GSM99_RS10695	ENOG4105CQC	Prephenate dehydratase
GSM99_RS10700	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GSM99_RS10710	ENOG4105C34	Pseudouridine synthase
GSM99_RS10715	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GSM99_RS10720	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GSM99_RS10750	ENOG4105T42	(LipO)protein
GSM99_RS10755	ENOG4105JIM	Phosphatidylserine synthase
GSM99_RS10765	ENOG4106IUH	DTW domain containing protein
GSM99_RS10770	ENOG4105EIB	trna rrna methyltransferase
GSM99_RS10775	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GSM99_RS10780	ENOG4105CW7	secretion protein, HlyD family
GSM99_RS10785	ENOG4105NTK	Transcriptional repressor Mpra
GSM99_RS10790	ENOG4105EQ0	Major Facilitator superfamily
GSM99_RS10800	ENOG41077RS	Phosphatase
GSM99_RS10805	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
GSM99_RS10825	ENOG4105GIJ	Glycine betaine
GSM99_RS10830	ENOG4108HQS	Glycine betaine
GSM99_RS10835	ENOG4108IJ7	Glycine betaine
GSM99_RS10845	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GSM99_RS10850	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
GSM99_RS10860	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GSM99_RS10865	ENOG4105VEQ	Cold shock protein
GSM99_RS10870	ENOG4107Z6W	Protein CrcB homolog
GSM99_RS10875	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GSM99_RS10880	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GSM99_RS10885	ENOG4108Z43	UPF0250 protein
GSM99_RS10890	ENOG4105DZ1	carboxypeptidase
GSM99_RS10895	ENOG4105K6T	rare lipoprotein A
GSM99_RS10900	ENOG4105CNI	cell division protein FtsW
GSM99_RS10905	ENOG4105CJN	penicillin-binding protein
GSM99_RS10910	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GSM99_RS10915	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GSM99_RS10925	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GSM99_RS10930	ENOG4105DJF	DNA polymerase III, delta' subunit
GSM99_RS10935	ENOG4108U2H	Rare lipoprotein B
GSM99_RS10940	ENOG4105C8T	Leucyl-tRNA synthetase
GSM99_RS10945	ENOG4105CDA	abc transporter atp-binding protein
GSM99_RS10950	ENOG4105DRP	amino acid AbC transporter
GSM99_RS10955	ENOG4105EAD	ABC transporter
GSM99_RS10960	ENOG4107RP9	extracellular solute-binding protein, family 3
GSM99_RS10990	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GSM99_RS10995	ENOG4108JU5	Magnesium and cobalt efflux protein
GSM99_RS11000	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GSM99_RS11005	ENOG4105C9A	Phoh family
GSM99_RS11010	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GSM99_RS11015	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GSM99_RS11020	ENOG4105C4W	S-formylglutathione hydrolase
GSM99_RS11070	ENOG4105E2R	ROK family
GSM99_RS11075	ENOG4105CE4	GlcNAc 6-P deacetylase
GSM99_RS11080	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GSM99_RS11085	ENOG4105CI1	PTS System
GSM99_RS11090	ENOG4108I1J	Integrase
GSM99_RS11195	ENOG4105CDU	Replicative dna helicase
GSM99_RS11205	ENOG4108V2F	protein ybcN in lambdoid DLP12 prophage regi
GSM99_RS11210	ENOG4108R1E	Serine threonine protein phosphatase 1
GSM99_RS11270	ENOG4108C66	Inherit from COG: DNA primase
GSM99_RS11375	ENOG4107XU6	Glycosyl transferase (Group 1
GSM99_RS11380	ENOG4105CX6	glutaminyL-tRNA synthetase
GSM99_RS11390	ENOG4105NX3	Membrane
GSM99_RS11395	ENOG41090R7	Ferric uptake
GSM99_RS11400	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GSM99_RS11405	ENOG4105NNH	LexA regulated protein
GSM99_RS11410	ENOG4105EV9	Alpha Beta Hydrolase
GSM99_RS11415	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GSM99_RS11420	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GSM99_RS11425	ENOG4108W15	Protein of unknown function (DUF1456)
GSM99_RS11440	ENOG4105XIQ	Protein of unknown function (DUF2517)
GSM99_RS11445	ENOG4107QNR	UPF0135 protein
GSM99_RS11455	ENOG4105DEG	Vwa containing coxe family protein
GSM99_RS11460	ENOG4105RD5	
GSM99_RS11475	ENOG4105C2C	drug resistance transporter, Bcr CflA
GSM99_RS11485	ENOG4105BZN	citrate synthase
GSM99_RS11490	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GSM99_RS11495	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GSM99_RS11500	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GSM99_RS11505	ENOG4105E33	succinate dehydrogenase
GSM99_RS11515	ENOG4105C7S	Dehydrogenase
GSM99_RS11520	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GSM99_RS11525	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GSM99_RS11530	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GSM99_RS11535	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GSM99_RS11545	ENOG4105KJB	cyd operon protein YbgE
GSM99_RS11550	ENOG4105HEI	LysR family (Transcriptional regulator
GSM99_RS11565	ENOG4107YD3	Thioesterase
GSM99_RS11570	ENOG4105E02	MotA TolQ exbB proton channel
GSM99_RS11575	ENOG4105M8F	Biopolymer transport protein exbD tolR
GSM99_RS11580	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
GSM99_RS11585	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GSM99_RS11590	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GSM99_RS11595	ENOG4105UFD	tol-pal system protein YbgF
GSM99_RS11620	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GSM99_RS11625	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSM99_RS11630	ENOG4105DKW	ABC transporter
GSM99_RS11635	ENOG4105D5K	Hemolysin activator protein
GSM99_RS11670	ENOG4105F4R	Transcriptional regulator mode
GSM99_RS11675	ENOG410680R	Protein of unknown function (DUF2592)
GSM99_RS11680	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GSM99_RS11690	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GSM99_RS11695	ENOG4108K4B	hydrolase
GSM99_RS11700	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GSM99_RS11705	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GSM99_RS11710	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GSM99_RS11715	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GSM99_RS11720	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GSM99_RS11730	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GSM99_RS11745	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GSM99_RS11750	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GSM99_RS11755	ENOG4105M00	molybdopterin converting factor, subunit 1
GSM99_RS11760	ENOG4108ZAF	Molybdopterin
GSM99_RS11765	ENOG4105HFZ	Membrane
GSM99_RS11770	ENOG4107QWP	ABC-2 type transporter
GSM99_RS11775	ENOG4107QWP	ABC-2 type transporter
GSM99_RS11780	ENOG4105CJ1	ABC, transporter
GSM99_RS11790	ENOG4107MVR	Transcriptional regulator
GSM99_RS11795	ENOG4105C1J	atp-dependent rna helicase
GSM99_RS11810	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GSM99_RS11870	ENOG4107TII	Recombinase
GSM99_RS11880	ENOG4105Y3U	Transglycosylase-associated protein
GSM99_RS11885	ENOG4105KHC	sulfurtransferase
GSM99_RS11895	ENOG4105CEE	C4-dicarboxylate transporter
GSM99_RS11905	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
GSM99_RS11915	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GSM99_RS11920	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GSM99_RS11925	ENOG4107NQ8	LysR family Transcriptional regulator
GSM99_RS11945	ENOG4108URH	decarboxylase
GSM99_RS11965	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GSM99_RS11975	ENOG4105D06	uba thif-type nad fad binding protein
GSM99_RS11985	ENOG4105CBP	Major Facilitator
GSM99_RS11995	ENOG4105DHF	Membrane
GSM99_RS12000	ENOG4107GZ4	SanA protein
GSM99_RS12005	ENOG4107R1I	NAD-dependent malic enzyme
GSM99_RS12010	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GSM99_RS12020	ENOG41067MG	lrgb family
GSM99_RS12025	ENOG4105VAW	lrga family
GSM99_RS12030	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GSM99_RS12035	ENOG4105D1F	ATP-binding protein
GSM99_RS12040	ENOG4105DBI	uridine monophosphokinase
GSM99_RS12045	ENOG4105DHP	deoxycytidine triphosphate deaminase
GSM99_RS12050	ENOG4108GAE	asmA family
GSM99_RS12055	ENOG4105CEE	C4-dicarboxylate transporter
GSM99_RS12065	ENOG4105EE5	Membrane protein terC
GSM99_RS12070	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GSM99_RS12075	ENOG4105KVH	Transcriptional regulator
GSM99_RS12080	ENOG4108RCM	Nitroreductase
GSM99_RS12095	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
GSM99_RS12100	ENOG4105C0A	alcohol dehydrogenase
GSM99_RS12105	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GSM99_RS12110	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GSM99_RS12115	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GSM99_RS12120	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GSM99_RS12125	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GSM99_RS12130	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GSM99_RS12135	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GSM99_RS12140	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GSM99_RS12145	ENOG4108535	NAD dependent epimerase/dehydratase family
GSM99_RS12150	ENOG4108TGY	Glutathione S-transferase
GSM99_RS12155	ENOG4105DZ1	carboxypeptidase
GSM99_RS12160	ENOG4105CKU	formyltetrahydrofolate synthetase
GSM99_RS12165	ENOG4105EJQ	L-serine dehydratase
GSM99_RS12170	ENOG4105C44	Serine transporter
GSM99_RS12175	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GSM99_RS12180	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GSM99_RS12185	ENOG41090BQ	Glutaredoxin
GSM99_RS12190	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
GSM99_RS12195	ENOG4108RMJ	sensory transduction regulator
GSM99_RS12200	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
GSM99_RS12210	ENOG4105DMR	ABC, transporter
GSM99_RS12215	ENOG4105GBT	ABC transporter
GSM99_RS12220	ENOG4106PMH	Extracellular solute-binding protein family 3
GSM99_RS12225	ENOG4105E5Z	arginine transporter ATP-binding subunit
GSM99_RS12235	ENOG4105DWU	Membrane
GSM99_RS12245	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GSM99_RS12250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSM99_RS12255	ENOG4105VEQ	Cold shock protein
GSM99_RS12260	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GSM99_RS12265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GSM99_RS12270	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GSM99_RS12275	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GSM99_RS12280	ENOG4108JJ8	(ABC) transporter
GSM99_RS12285	ENOG4108JJ9	ABC, transporter
GSM99_RS12290	ENOG4105C3M	thioredoxin reductase
GSM99_RS12295	ENOG4105EW9	transcriptional regulator AsnC family
GSM99_RS12300	ENOG4105CNU	cell division protein FtsK
GSM99_RS12305	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GSM99_RS12310	ENOG4105D1H	recombination factor protein RarA
GSM99_RS12315	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GSM99_RS12325	ENOG4105DG4	malate L-lactate dehydrogenase
GSM99_RS12340	ENOG4105F1A	Pyruvate formate-lyase
GSM99_RS12345	ENOG4105C6N	Formate acetyltransferase
GSM99_RS12350	ENOG4105TMB	Formate nitrite transporter
GSM99_RS12355	ENOG4105DDY	UPF0142 protein ycaO
GSM99_RS12360	ENOG4105HDK	L-asparaginase
GSM99_RS12370	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GSM99_RS12375	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GSM99_RS12380	ENOG4105CAT	Cytidine monophosphate kinase
GSM99_RS12385	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GSM99_RS12390	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GSM99_RS12395	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GSM99_RS12400	ENOG4105BZ1	(ABC) transporter
GSM99_RS12405	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GSM99_RS12415	ENOG4105W49	UPF0434 protein
GSM99_RS12420	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GSM99_RS12425	ENOG4107S90	membrAne
GSM99_RS12430	ENOG4106371	Methyltransferase
GSM99_RS12435	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GSM99_RS12440	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GSM99_RS12445	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GSM99_RS12460	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GSM99_RS12475	ENOG4105FCK	Membrane
GSM99_RS12480	ENOG4105C5S	asparaginyl-tRNA synthetase
GSM99_RS12485	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GSM99_RS12490	ENOG4105CD8	aminopeptidase N
GSM99_RS12495	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GSM99_RS12500	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GSM99_RS12505	ENOG4105QVC	MOSC domain-containing protein
GSM99_RS12510	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GSM99_RS12515	ENOG4105C5H	ABC transporter
GSM99_RS12520	ENOG4105F1S	paraquat-inducible protein a
GSM99_RS12525	ENOG4105DY2	Paraquat-inducible protein b
GSM99_RS12530	ENOG4108Q2G	(LipO)protein
GSM99_RS12540	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
GSM99_RS12545	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GSM99_RS12550	ENOG4105DAN	ATP-dependent protease
GSM99_RS12555	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GSM99_RS12575	ENOG4105EM2	membrane
GSM99_RS12580	ENOG41088T4	Helicase IV
GSM99_RS12585	ENOG4108Z5K	methylglyoxal synthase
GSM99_RS12590	ENOG4105K4P	CoA-binding domain protein
GSM99_RS12595	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
GSM99_RS12600	ENOG410855V	Acylphosphatase
GSM99_RS12605	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GSM99_RS12615	ENOG4105DU0	nucleoside hydrolase
GSM99_RS12620	ENOG4105D9N	nucleoside
GSM99_RS12625	ENOG4108RVA	ribokinase
GSM99_RS12630	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GSM99_RS12645	ENOG4107R11	Transcriptional regulator
GSM99_RS12655	ENOG4108YS1	cytoplasmic protein
GSM99_RS12660	ENOG4105DVC	DnaJ domain protein
GSM99_RS12665	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
GSM99_RS12670	ENOG4105CH2	amidohydrolase
GSM99_RS12675	ENOG4105DUM	transcriptional regulator, lysR family
GSM99_RS12685	ENOG4105UEI	Transcriptional Regulator AraC Family
GSM99_RS12695	ENOG4105TIE	Aminoglycoside 2'-N-acetyltransferase
GSM99_RS12705	ENOG4105VEQ	Cold shock protein
GSM99_RS12710	ENOG4105D1S	lipid A biosynthesis
GSM99_RS12760	ENOG4105MPK	DNA polymerase III subunit theta
GSM99_RS12770	ENOG4105E68	Sulfatase
GSM99_RS12780	ENOG4106V8H	Nucleoid-associated protein
GSM99_RS12785	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GSM99_RS12790	ENOG4105CFI	type iii restriction protein res subunit
GSM99_RS12795	ENOG4105I08	Pseudouridine synthase
GSM99_RS12800	ENOG4105C2C	drug resistance transporter, Bcr CflA
GSM99_RS12805	ENOG4105HG6	
GSM99_RS12810	ENOG4107TT5	NLP P60 protein
GSM99_RS12815	ENOG41076MN	Phosphoesterase, PA-phosphatase related
GSM99_RS12830	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GSM99_RS12840	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GSM99_RS12845	ENOG4105DE4	1-phosphofructokinase
GSM99_RS12850	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GSM99_RS12855	ENOG4105HMI	Membrane
GSM99_RS12860	ENOG4105DUM	transcriptional regulator, lysR family
GSM99_RS12865	ENOG4108IQI	permease
GSM99_RS12870	ENOG4105EHG	Permease protein
GSM99_RS12875	ENOG4105E0A	ABC, transporter
GSM99_RS12880	ENOG4105D05	Receptor
GSM99_RS12890	ENOG4105CUB	amino acid
GSM99_RS12900	ENOG4108VCD	Chaperone
GSM99_RS12935	ENOG4105D5K	Hemolysin activator protein
GSM99_RS12940	ENOG4105CKT	filamentous hemagglutinin
GSM99_RS12945	ENOG4105CKT	filamentous hemagglutinin
GSM99_RS12990	ENOG4107RA9	decarboxylase
GSM99_RS12995	ENOG4105CMU	LysR family (Transcriptional regulator
GSM99_RS13000	ENOG4105CXG	d-lactate dehydrogenase
GSM99_RS13005	ENOG4105CJB	Exodeoxyribonuclease I
GSM99_RS13010	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
GSM99_RS13015	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
GSM99_RS13020	ENOG41090HJ	UPF0265 protein
GSM99_RS13025	ENOG4107QQB	Ribonuclease E
GSM99_RS13030	ENOG4105EI2	Pseudouridine synthase
GSM99_RS13045	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GSM99_RS13050	ENOG4105VGS	50s ribosomal protein l32
GSM99_RS13060	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GSM99_RS13070	ENOG4105CHR	reductase
GSM99_RS13075	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GSM99_RS13095	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GSM99_RS13100	ENOG4107QRG	dna polymerase iii
GSM99_RS13105	ENOG4105F8V	Hydrolase, tatD family
GSM99_RS13110	ENOG4105K59	histidine triad (HIT) protein
GSM99_RS13115	ENOG41090DQ	Lipoprotein
GSM99_RS13120	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
GSM99_RS13130	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GSM99_RS13145	ENOG4107MBR	17 kDa surface antigen
GSM99_RS13150	ENOG4108JA2	transcriptioN-repair coupling factor
GSM99_RS13155	ENOG4105D60	lipoprotein releasing system transmembrane protein
GSM99_RS13160	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GSM99_RS13165	ENOG4105D60	lipoprotein releasing system transmembrane protein
GSM99_RS13185	ENOG4105EZE	Cupin 4 family protein
GSM99_RS13190	ENOG4105IFJ	Histidine kinase
GSM99_RS13195	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GSM99_RS13200	ENOG4107QTF	adenylosuccinate lyase
GSM99_RS13205	ENOG41075W9	High frequency lysogenization protein HflD homolog
GSM99_RS13210	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GSM99_RS13225	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GSM99_RS13235	ENOG4105VEQ	Cold shock protein
GSM99_RS13240	ENOG4108ZNX	Heat shock protein
GSM99_RS13245	ENOG4105GTN	ParB Domain Protein Nuclease
GSM99_RS13250	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
GSM99_RS13255	ENOG4108WF3	methyltransferase
GSM99_RS13315	ENOG4105Z2P	Protein of unknown function (DUF465)
GSM99_RS13385	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GSM99_RS13390	ENOG4105HRS	Antitermination protein
GSM99_RS13395	ENOG4107IFA	Lipase (EC 3.1.1.3)
GSM99_RS13400	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
GSM99_RS13405	ENOG4107SSZ	Phosphatase
GSM99_RS13415	ENOG4106MMI	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GSM99_RS13430	ENOG4108RW8	Universal stress protein F
GSM99_RS13435	ENOG41090A1	ferritin
GSM99_RS13440	ENOG4105FXM	Copper resistance protein
GSM99_RS13445	ENOG4108PNC	copper resistance
GSM99_RS13450	ENOG4105NKT	exported protein
GSM99_RS13460	ENOG4105DY2	Paraquat-inducible protein b
GSM99_RS13465	ENOG4105H2K	paraquat-inducible protein a
GSM99_RS13470	ENOG4108ZGC	gaf domain protein
GSM99_RS13480	ENOG4105CN1	protease
GSM99_RS13490	ENOG4105D0M	Protease HtpX homolog
GSM99_RS13500	ENOG4108ETY	sodium dicarboxylate symporter
GSM99_RS13505	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GSM99_RS13510	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GSM99_RS13515	ENOG4107PN8	YfeABCD locus regulator
GSM99_RS13520	ENOG4105FGM	Fructosamine kinase
GSM99_RS13525	ENOG4105CC5	ABC transporter
GSM99_RS13530	ENOG4105CC5	ABC transporter
GSM99_RS13535	ENOG4105DIK	(ABC) transporter
GSM99_RS13540	ENOG4105DSE	periplasmic solute binding protein
GSM99_RS13560	ENOG4108Z7R	Chaperone CsaA
GSM99_RS13575	ENOG4105C22	threonyL-tRNA synthetase
GSM99_RS13580	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GSM99_RS13585	ENOG41082NX	50s ribosomal protein l35
GSM99_RS13590	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GSM99_RS13600	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GSM99_RS13605	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GSM99_RS13610	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GSM99_RS13615	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GSM99_RS13625	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GSM99_RS13630	ENOG4105CKK	Glycosyl transferase, family 2
GSM99_RS13635	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GSM99_RS13640	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GSM99_RS13645	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GSM99_RS13650	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GSM99_RS13655	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GSM99_RS13675	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GSM99_RS13680	ENOG4105EHG	Permease protein
GSM99_RS13685	ENOG4107R4I	Periplasmic binding protein
GSM99_RS13690	ENOG4106QJH	hemin transport protein
GSM99_RS13695	ENOG4107ENK	receptor
GSM99_RS13700	ENOG4107ENK	receptor
GSM99_RS13705	ENOG4107F3C	Hemin uptake protein
GSM99_RS13710	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GSM99_RS13725	ENOG4105IPI	Membrane
GSM99_RS13765	ENOG4105C9B	Cysteine desulfurase
GSM99_RS13770	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GSM99_RS13775	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GSM99_RS13785	ENOG4105KMX	major outer membrane lipoprotein
GSM99_RS13790	ENOG4105CA9	Pyruvate kinase
GSM99_RS13805	ENOG4107QI1	Mate efflux family protein
GSM99_RS13810	ENOG4108R6K	riboflavin synthase, subunit alpha
GSM99_RS13815	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GSM99_RS13820	ENOG4105CZQ	inner membrane transport protein YdhC
GSM99_RS13825	ENOG4105F52	Transcriptional regulator
GSM99_RS13830	ENOG4105ETE	Transcriptional regulator (LacI family
GSM99_RS13840	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GSM99_RS13860	ENOG4105M2J	Glutaredoxin
GSM99_RS13865	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GSM99_RS13870	ENOG4108UYE	Lactoylglutathione lyase
GSM99_RS13875	ENOG4105XZD	Fe-S protein
GSM99_RS13900	ENOG4108XTF	Outer Membrane Lipoprotein
GSM99_RS13905	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GSM99_RS13910	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GSM99_RS13915	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GSM99_RS13920	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GSM99_RS13940	ENOG4108JQ2	peptide transport system atp-binding protein
GSM99_RS13945	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GSM99_RS13965	ENOG4105E51	psp operon transcriptional activator
GSM99_RS13970	ENOG41087YS	Phage shock protein A
GSM99_RS13975	ENOG4105YYT	phage shock protein B
GSM99_RS13980	ENOG4105FM1	phage shock protein C
GSM99_RS13990	ENOG4105CM6	amino acid regulated cytosolic protein
GSM99_RS13995	ENOG4106K28	UPF0283 membrane protein
GSM99_RS14010	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GSM99_RS14015	ENOG4107QSI	ABC, transporter
GSM99_RS14030	ENOG4107RX3	Mg2 transporter protein cora family protein
GSM99_RS14060	ENOG4108T1M	outer membrane protein x
GSM99_RS14075	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GSM99_RS14090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GSM99_RS14105	ENOG4105NAU	thioesterase Superfamily protein
GSM99_RS14110	ENOG4107835	probably involved in intracellular septation (By similarity)
GSM99_RS14120	ENOG4108S3I	UPF0259 membrane protein
GSM99_RS14135	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GSM99_RS14145	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GSM99_RS14155	ENOG4105DDQ	anthranilate synthase
GSM99_RS14160	ENOG4105CRQ	synthase (Component I)
GSM99_RS14165	ENOG4105DB7	PHP domain protein
GSM99_RS14170	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GSM99_RS14175	ENOG4105FE9	pseudouridine synthase
GSM99_RS14185	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GSM99_RS14190	ENOG4105UBK	short-chain dehydrogenase reductase
GSM99_RS14195	ENOG4105ERU	peptidase
GSM99_RS14200	ENOG4105RKX	Protein of unknown function (DUF2498)
GSM99_RS14205	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GSM99_RS14215	ENOG4107R11	Transcriptional regulator
GSM99_RS14235	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GSM99_RS14240	ENOG4105EYK	Phosphatidylglycerophosphatase B
GSM99_RS14245	ENOG4105Q4A	inner membrane protein yciS
GSM99_RS14250	ENOG4105CFV	Tetratricopeptide repeat protein
GSM99_RS14255	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GSM99_RS14260	ENOG4108ZJT	translation initiation factor, Sui1
GSM99_RS14265	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
GSM99_RS14270	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GSM99_RS14285	ENOG4108UQQ	Electron transport complex
GSM99_RS14310	ENOG4105DGN	Electron transport complex
GSM99_RS14315	ENOG4105M9B	inner membrane protein ydgK
GSM99_RS14320	ENOG4105D9R	oxidoreductase
GSM99_RS14345	ENOG4106J39	exported protein
GSM99_RS14350	ENOG4105C9Q	fumarate hydratase class II
GSM99_RS14360	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
GSM99_RS14370	ENOG4105D94	Major Facilitator Superfamily
GSM99_RS14375	ENOG4106NZI	LysR family Transcriptional regulator
GSM99_RS14380	ENOG4105DAG	ROK family
GSM99_RS14385	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GSM99_RS14390	ENOG4105KBG	Protein of unknown function (DUF1161)
GSM99_RS14395	ENOG4105M5Q	UPF0482 protein
GSM99_RS14400	ENOG4105EMU	Dehydrogenase
GSM99_RS14405	ENOG41061RM	osmotically inducible lipoprotein
GSM99_RS14410	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
GSM99_RS14415	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GSM99_RS14430	ENOG4105KBH	arsR family transcriptional regulator
GSM99_RS14445	ENOG4105EZE	Cupin 4 family protein
GSM99_RS14450	ENOG4105M0C	cytoplasmic protein
GSM99_RS14460	ENOG4108ZHR	arsR family transcriptional regulator
GSM99_RS14485	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GSM99_RS14490	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GSM99_RS14500	ENOG4105T16	Transcriptional regulator (AraC family)
GSM99_RS14505	ENOG4105C87	Aminotransferase class I and II
GSM99_RS14510	ENOG4105DFD	Na H antiporter
GSM99_RS14545	ENOG4105R8A	Heat shock protein
GSM99_RS14555	ENOG4105CC0	LysR family Transcriptional regulator
GSM99_RS14575	ENOG4107QHE	Choloylglycine hydrolase
GSM99_RS14585	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GSM99_RS14615	ENOG4105FQP	Beta-lactamase
GSM99_RS14625	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GSM99_RS14635	ENOG4108UPT	UPF0178 protein
GSM99_RS14640	ENOG4108KTG	Membrane protein, drug metabolite transporter
GSM99_RS14645	ENOG4108ZT1	Transcriptional regulator
GSM99_RS14655	ENOG4107R4I	Periplasmic binding protein
GSM99_RS14660	ENOG4105D4P	Coproporphyrinogen iii oxidase
GSM99_RS14665	ENOG41090JE	Utilization Protein
GSM99_RS14675	ENOG4105C5H	ABC transporter
GSM99_RS14690	ENOG4105JQN	Transcriptional regulator
GSM99_RS14695	ENOG4105F27	Major Facilitator
GSM99_RS14705	ENOG4105C57	major facilitator superfamily
GSM99_RS14745	ENOG4105D01	(LipO)protein
GSM99_RS14795	ENOG4105V0I	UPF0267 protein
GSM99_RS14825	ENOG4108UW5	maltose o-acetyltransferase
GSM99_RS14845	ENOG4105ETT	transcriptional Regulator, LysR family
GSM99_RS14850	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GSM99_RS14855	ENOG4108ESZ	Glycogen debranching enzyme
GSM99_RS14860	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GSM99_RS14865	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GSM99_RS14870	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GSM99_RS14890	ENOG4105KME	endoribonuclease L-psp
GSM99_RS14900	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GSM99_RS14910	ENOG4105CMT	Dihydroxyacetone kinase
GSM99_RS14970	ENOG4105QAX	Iron-sulfur
GSM99_RS14975	ENOG4107KGK	dmso reductase anchor subunit
GSM99_RS14980	ENOG4108NEM	leader-binding protein dmsD
GSM99_RS15000	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GSM99_RS15005	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GSM99_RS15010	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GSM99_RS15015	ENOG4105C08	Histidine kinase
GSM99_RS15020	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GSM99_RS15040	ENOG4105CMI	transporter
GSM99_RS15045	ENOG4105CJ1	ABC, transporter
GSM99_RS15050	ENOG4105D0S	secretion protein (HlyD
GSM99_RS15055	ENOG4105D44	asparaginase
GSM99_RS15060	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSM99_RS15065	ENOG4105FYV	Amp nucleosidase
GSM99_RS15095	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GSM99_RS15110	ENOG4108JU3	Alkyl hydroperoxide reductase
GSM99_RS15115	ENOG4105D3R	alkyl hydroperoxide reductase
GSM99_RS15130	ENOG4105NTW	Transcriptional regulator
GSM99_RS15155	ENOG4105QAX	Iron-sulfur
GSM99_RS15160	ENOG4107QY8	reductase
GSM99_RS15165	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GSM99_RS15170	ENOG4105Q9Y	Universal stress protein
GSM99_RS15175	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GSM99_RS15180	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GSM99_RS15185	ENOG4105C5D	exported protein
GSM99_RS15190	ENOG4105D5Q	Arginine ornithine antiporter
GSM99_RS15195	ENOG4105CQ7	ATP-dependent helicase
GSM99_RS15210	ENOG4108VCD	Chaperone
GSM99_RS15215	ENOG4106PG1	outer membrane usher protein
GSM99_RS15225	ENOG4105WXT	Conserved Protein
GSM99_RS15230	ENOG410689M	(LipO)protein
GSM99_RS15235	ENOG4107H52	Dicarboxylate transport
GSM99_RS15240	ENOG4105C5I	Dehydrogenase
GSM99_RS15245	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS15260	ENOG4105UEI	Transcriptional Regulator AraC Family
GSM99_RS15275	ENOG41083J0	(ABC) transporter
GSM99_RS15280	ENOG4105C4B	ABC transporter, permease
GSM99_RS15295	ENOG4108ZZ3	UPF0260 protein
GSM99_RS15300	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GSM99_RS15310	ENOG4105VNG	YcgL domain-containing protein
GSM99_RS15315	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GSM99_RS15320	ENOG4107QMS	site-determining protein
GSM99_RS15325	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GSM99_RS15330	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GSM99_RS15335	ENOG4105CEY	Amp-dependent synthetase and ligase
GSM99_RS15340	ENOG4105Y4Z	Outer Membrane Lipoprotein
GSM99_RS15345	ENOG41072GX	Peptidase M22 Glycoprotease
GSM99_RS15350	ENOG4105DVT	helicase
GSM99_RS15355	ENOG4105M4H	endoribonuclease L-psp
GSM99_RS15360	ENOG4105CGD	Nad-dependent epimerase dehydratase
GSM99_RS15365	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
GSM99_RS15370	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GSM99_RS15375	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GSM99_RS15380	ENOG4106KNT	transcriptional regulator
GSM99_RS15385	ENOG4105CA9	Pyruvate kinase
GSM99_RS15390	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GSM99_RS15395	ENOG4105DR5	peptidase
GSM99_RS15400	ENOG4105NXV	High-affinity zinc uptake system protein
GSM99_RS15405	ENOG4105FDK	ABC transporter
GSM99_RS15410	ENOG4105FAV	ABC, transporter
GSM99_RS15420	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GSM99_RS15425	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GSM99_RS15430	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GSM99_RS15435	ENOG4105CDY	transcriptional regulatory protein
GSM99_RS15440	ENOG4108TIT	dATP pyrophosphohydrolase
GSM99_RS15450	ENOG4105WJG	Glutathione
GSM99_RS15455	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GSM99_RS15460	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GSM99_RS15470	ENOG4105C5H	ABC transporter
GSM99_RS15475	ENOG4106N3A	copper homeostasis protein cutc
GSM99_RS15480	ENOG4106ZCM	YecM protein
GSM99_RS15510	ENOG4105D9U	N-acetyltransferase
GSM99_RS15520	ENOG4105F3T	(LipO)protein
GSM99_RS15525	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
GSM99_RS15550	ENOG4105CHH	sulfate transporter
GSM99_RS15555	ENOG4105N5T	Radical SAM Protein
GSM99_RS15560	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GSM99_RS15565	ENOG41063JG	Transcriptional regulator
GSM99_RS15570	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GSM99_RS15575	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GSM99_RS15580	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GSM99_RS15585	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GSM99_RS15590	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GSM99_RS15595	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GSM99_RS15600	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
GSM99_RS15605	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GSM99_RS15635	ENOG4105C7K	acetolactate synthase
GSM99_RS15660	ENOG4108JJB	ABC transporter
GSM99_RS15680	ENOG4107YCY	Transcriptional regulator
GSM99_RS15685	ENOG4105D5U	fad dependent oxidoreductase
GSM99_RS15705	ENOG4105EW9	transcriptional regulator AsnC family
GSM99_RS15710	ENOG4108NIW	Leucine export protein LeuE
GSM99_RS15720	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GSM99_RS15725	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GSM99_RS15730	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GSM99_RS15740	ENOG4105KAF	membrAne
GSM99_RS15750	ENOG4108TTM	chaperone
GSM99_RS15755	ENOG4108MQF	Chaperone
GSM99_RS15775	ENOG4105GQR	Chaperone
GSM99_RS15785	ENOG4105D5M	phosphate starvation-inducible protein
GSM99_RS15795	ENOG4105RWS	endonuclease I
GSM99_RS15805	ENOG4107XM3	UPF0442 protein
GSM99_RS15810	ENOG4105DWK	Membrane
GSM99_RS15820	ENOG4108U51	Universal stress protein
GSM99_RS15830	ENOG4108U51	Universal stress protein
GSM99_RS15835	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GSM99_RS15840	ENOG4105XVG	cytoplasmic protein
GSM99_RS15850	ENOG4105D52	delta-aminolevulinic acid dehydratase
GSM99_RS15870	ENOG4105DZC	cytosine deaminase
GSM99_RS15875	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
GSM99_RS15880	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
GSM99_RS15890	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GSM99_RS15895	ENOG4105C94	Transporter
GSM99_RS15900	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GSM99_RS15910	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GSM99_RS15940	ENOG4108JQ7	(ABC) transporter
GSM99_RS15945	ENOG4105C3U	ABC transporter
GSM99_RS15950	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS15960	ENOG4107QSI	ABC, transporter
GSM99_RS15965	ENOG4107QSI	ABC, transporter
GSM99_RS15975	ENOG4105WZK	nitrite reductase NADPH small subunit
GSM99_RS15980	ENOG4107QZF	nitrite reductase NADPH large subunit
GSM99_RS15985	ENOG4105DEF	Extracellular solute-binding protein, family 5
GSM99_RS15990	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS15995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSM99_RS16000	ENOG4105C3U	ABC transporter
GSM99_RS16005	ENOG4108JQ7	(ABC) transporter
GSM99_RS16010	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GSM99_RS16015	ENOG4108EKI	Dehydrogenase
GSM99_RS16020	ENOG4107104	thymidine kinase
GSM99_RS16035	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GSM99_RS16040	ENOG4105I93	response regulator
GSM99_RS16045	ENOG4105K5B	UPF0225 protein
GSM99_RS16050	ENOG4105CIY	formyltetrahydrofolate deformylase
GSM99_RS16065	ENOG4105SKE	transcriptional Regulator LysR family
GSM99_RS16070	ENOG4105CGK	Exodeoxyribonuclease III
GSM99_RS16075	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GSM99_RS16080	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GSM99_RS16085	ENOG41069NU	Nitroreductase
GSM99_RS16090	ENOG4105D07	Signal peptide peptidase, SppA
GSM99_RS16095	ENOG4105HDK	L-asparaginase
GSM99_RS16100	ENOG4108RWI	nicotinamidase
GSM99_RS16105	ENOG4105VUT	cytoplasmic protein
GSM99_RS16110	ENOG4105E0X	reductase
GSM99_RS16120	ENOG4105DSB	aldose 1-epimerase
GSM99_RS16125	ENOG4105GNX	MltA-interacting MipA family protein
GSM99_RS16130	ENOG4105C8H	hydrogenase maturation protein Hypf
GSM99_RS16140	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GSM99_RS16145	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GSM99_RS16150	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GSM99_RS16155	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GSM99_RS16165	ENOG410814C	multidrug resistance protein
GSM99_RS16190	ENOG4105CF7	AraC family transcriptional regulator
GSM99_RS16195	ENOG4107QW4	alcohol dehydrogenase
GSM99_RS16270	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GSM99_RS16275	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GSM99_RS16280	ENOG4105WH1	Two component transcriptional regulator luxr family
GSM99_RS16300	ENOG4105CBT	Fructose-1,6-bisphosphatase
GSM99_RS16305	ENOG41080QX	K07048 phosphotriesterase-related protein
GSM99_RS16360	ENOG4108VEN	abc transporter atp-binding protein
GSM99_RS16370	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
GSM99_RS16380	ENOG4105VF7	tolerance protein
GSM99_RS16395	ENOG410756H	nucleotidyltransferase
GSM99_RS16420	ENOG4108R0M	Aminoglycoside
GSM99_RS16515	ENOG4105DFP	Integrase
GSM99_RS16520	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GSM99_RS16525	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GSM99_RS16530	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GSM99_RS16540	ENOG4105CUG	Oligopeptidase b
GSM99_RS16555	ENOG4105C6K	Malic enzyme
GSM99_RS16560	ENOG4105WH1	Two component transcriptional regulator luxr family
GSM99_RS16570	ENOG4105KUZ	arsenate reductase
GSM99_RS16575	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GSM99_RS16585	ENOG4105WD1	Membrane
GSM99_RS16590	ENOG4105XYK	UPF0370 protein
GSM99_RS16595	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GSM99_RS16600	ENOG4108VMM	UPF0756 membrane protein
GSM99_RS16605	ENOG4105CGZ	zinc metallopeptidase
GSM99_RS16610	ENOG4105D29	Helix-turn-helix type 11 domain protein
GSM99_RS16620	ENOG4105C8V	SAICAR synthetase
GSM99_RS16630	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GSM99_RS16635	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GSM99_RS16640	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GSM99_RS16645	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GSM99_RS16650	ENOG4105C02	permease
GSM99_RS16655	ENOG4105ERG	peptidase m48, ste24p
GSM99_RS16660	ENOG4105K89	arsenate reductase
GSM99_RS16665	ENOG4105EAA	nucleoside
GSM99_RS16670	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
GSM99_RS16675	ENOG4105CUY	Mechanosensitive ion channel
GSM99_RS16680	ENOG4105C2W	permease
GSM99_RS16685	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GSM99_RS16690	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GSM99_RS16695	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GSM99_RS16700	ENOG4108MK9	spermidine N(1)-acetyltransferase
GSM99_RS16705	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GSM99_RS16710	ENOG4105C9X	ppx gppa phosphatase
GSM99_RS16715	ENOG4105CJW	magnesium transporter
GSM99_RS16730	ENOG4105DUX	Transporter
GSM99_RS16735	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GSM99_RS16740	ENOG4105BZS	acriflavin resistance protein
GSM99_RS16745	ENOG4105BZS	acriflavin resistance protein
GSM99_RS16750	ENOG4105EB3	Histidine kinase
GSM99_RS16755	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GSM99_RS16760	ENOG4105CFP	Peptidase U32
GSM99_RS16765	ENOG4107TE5	Lipid kinase
GSM99_RS16770	ENOG4105EIE	fructose-bisphosphate aldolase
GSM99_RS16775	ENOG4105DWF	phosphomethylpyrimidine kinase
GSM99_RS16780	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
GSM99_RS16785	ENOG4105C85	amino acid
GSM99_RS16795	ENOG4108W3Q	Transcriptional regulator
GSM99_RS16800	ENOG410667J	hydrolase
GSM99_RS16805	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GSM99_RS16810	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
GSM99_RS16815	ENOG4105BZG	amino acid carrier protein
GSM99_RS16820	ENOG4105MPK	DNA polymerase III subunit theta
GSM99_RS16830	ENOG4105X5C	UPF0181 protein
GSM99_RS16835	ENOG4105CRQ	synthase (Component I)
GSM99_RS16840	ENOG4105P8F	nudix hydrolase
GSM99_RS16850	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
GSM99_RS16855	ENOG4105DHI	Methyltransferase
GSM99_RS16860	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
GSM99_RS16870	ENOG4105RHY	Pfam:UPF0157
GSM99_RS17005	ENOG4105ED4	portal protein
GSM99_RS17020	ENOG4105VZ1	Replication Protein
GSM99_RS17060	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GSM99_RS17075	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSM99_RS17085	ENOG4108VEV	chaperone
GSM99_RS17140	ENOG4105CK7	Sodium proline symporter
GSM99_RS17145	ENOG4105C26	Dehydrogenase
GSM99_RS17150	ENOG4108M9K	flagella biosynthesis protein FliZ
GSM99_RS17155	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSM99_RS17160	ENOG4105I03	Flagellin
GSM99_RS17165	ENOG4105I03	Flagellin
GSM99_RS17175	ENOG4105DTS	flagellar hook-associated
GSM99_RS17180	ENOG4105MQ3	flagellar protein FliS
GSM99_RS17185	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
GSM99_RS17190	ENOG4107YB6	acetyltransferase, (GNAT) family
GSM99_RS17215	ENOG4105RA2	Membrane
GSM99_RS17225	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GSM99_RS17230	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GSM99_RS17235	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GSM99_RS17240	ENOG41090PJ	Flagellar assembly protein
GSM99_RS17245	ENOG4108JIR	Flagellum-specific ATP synthase
GSM99_RS17250	ENOG4105GSA	Flagellar export protein flij
GSM99_RS17255	ENOG4105WF4	Flagellar hook-length control protein
GSM99_RS17260	ENOG4107ZI8	flagellar basal body-associated protein flil
GSM99_RS17265	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GSM99_RS17270	ENOG4105DD5	Flagellar motor switch protein
GSM99_RS17275	ENOG4105K0P	flagellar biosynthesis protein
GSM99_RS17280	ENOG4105CN7	Flagellar biosynthetic protein FliP
GSM99_RS17285	ENOG4105VS8	Flagellar biosynthetic protein fliq
GSM99_RS17290	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GSM99_RS17305	ENOG4105DTJ	flagellar hook-associated protein
GSM99_RS17310	ENOG4105E1Q	flagellar hook-associated protein
GSM99_RS17315	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GSM99_RS17320	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GSM99_RS17325	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GSM99_RS17330	ENOG4105CGA	flagellar basal-body rod protein FlgG
GSM99_RS17335	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GSM99_RS17340	ENOG4105BZE	flagellar hook protein, FlgE
GSM99_RS17345	ENOG4105W00	Flagellar hook capping protein
GSM99_RS17350	ENOG4108ZC9	flagellar basal-body rod protein flgc
GSM99_RS17355	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GSM99_RS17360	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
GSM99_RS17365	ENOG4105M9M	anti-sigma28 factor FlgM
GSM99_RS17370	ENOG4105QVD	Flagella synthesis protein FlgN
GSM99_RS17375	ENOG4105D7B	Flagellar biosynthesis protein flha
GSM99_RS17380	ENOG4105D00	flagellar biosynthetic protein flhB
GSM99_RS17385	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GSM99_RS17390	ENOG4108VYJ	response regulator receiver protein
GSM99_RS17395	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GSM99_RS17400	ENOG4105BZU	Histidine kinase
GSM99_RS17405	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS17410	ENOG4105C8Q	Methyl-accepting chemotaxis
GSM99_RS17415	ENOG4108V3W	Chemotaxis protein, CheW
GSM99_RS17420	ENOG4105CBS	Chea signal transduction histidine kinase
GSM99_RS17425	ENOG4105ER2	Ompa motb domain protein
GSM99_RS17430	ENOG4107RD7	Flagellar Motor Protein, MotA
GSM99_RS17435	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
GSM99_RS17440	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
GSM99_RS17470	ENOG4105VEQ	Cold shock protein
GSM99_RS17475	ENOG4105GSJ	Inner membrane protein ylaC
GSM99_RS17485	ENOG4105NF4	modulator of drug activity
GSM99_RS17490	ENOG4105CF7	AraC family transcriptional regulator
GSM99_RS17510	ENOG4105EKE	dihydroorotase
GSM99_RS17515	ENOG4105PVA	Biofilm formation regulatory protein BssS
GSM99_RS17525	ENOG4105DB1	molybdopterin oxidoreductase
GSM99_RS17530	ENOG4106WHD	Tetrathionate reductase
GSM99_RS17535	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GSM99_RS17540	ENOG4106AFQ	Histidine kinase
GSM99_RS17545	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GSM99_RS17550	ENOG4105D1S	lipid A biosynthesis
GSM99_RS17555	ENOG4105C6X	Major Facilitator
GSM99_RS17565	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GSM99_RS17590	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GSM99_RS17625	ENOG4108UMN	azlc family
GSM99_RS17635	ENOG4105F0I	Aminotransferase
GSM99_RS17640	ENOG4108YK4	Acid-resistance membrane protein
GSM99_RS17650	ENOG4105CUY	Mechanosensitive ion channel
GSM99_RS17660	ENOG4105QAX	Iron-sulfur
GSM99_RS17665	ENOG4107KGK	dmso reductase anchor subunit
GSM99_RS17680	ENOG4105UEI	Transcriptional Regulator AraC Family
GSM99_RS17780	ENOG4108XTP	Transcriptional regulator
GSM99_RS17810	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
GSM99_RS17815	ENOG41068CG	regulatoR
GSM99_RS17825	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSM99_RS17830	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GSM99_RS17840	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GSM99_RS17845	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GSM99_RS17850	ENOG4105XPH	Ferredoxin
GSM99_RS17855	ENOG4105M5B	(LipO)protein
GSM99_RS17860	ENOG4105E0U	tyrosine-specific transport protein
GSM99_RS17870	ENOG4105CH6	catalase
GSM99_RS17875	ENOG4105CEY	Amp-dependent synthetase and ligase
GSM99_RS17880	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GSM99_RS17885	ENOG4108IPT	Naphthoate synthase
GSM99_RS17890	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GSM99_RS17895	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GSM99_RS17900	ENOG4105E4F	Isochorismate synthase
GSM99_RS17915	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSM99_RS17920	ENOG4105C8S	subunit m
GSM99_RS17930	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSM99_RS17935	ENOG4107UFS	subunit j
GSM99_RS17940	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSM99_RS17945	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GSM99_RS17950	ENOG4107R0R	NADH dehydrogenase subunit g
GSM99_RS17955	ENOG4107QIZ	NADH dehydrogenase
GSM99_RS17960	ENOG4105GKE	subunit e
GSM99_RS17965	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSM99_RS17970	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSM99_RS17975	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GSM99_RS17980	ENOG4107NQ8	LysR family Transcriptional regulator
GSM99_RS17985	ENOG4105CHM	Aminotransferase
GSM99_RS17990	ENOG4105DK2	UPF0207 protein
GSM99_RS18000	ENOG4107QWE	)-transporter
GSM99_RS18010	ENOG4105XWI	UPF0304 protein
GSM99_RS18015	ENOG4105PQ6	UPF0208 membrane protein
GSM99_RS18020	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GSM99_RS18035	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GSM99_RS18050	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
GSM99_RS18055	ENOG4105ETE	Transcriptional regulator (LacI family
GSM99_RS18060	ENOG4105PTV	Nudix Hydrolase
GSM99_RS18065	ENOG4105CYM	Glutathione S-transferase
GSM99_RS18070	ENOG4105ECP	epimerase
GSM99_RS18075	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GSM99_RS18080	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GSM99_RS18085	ENOG4105E96	Colicin v production protein
GSM99_RS18090	ENOG4108S3P	Sporulation domain protein
GSM99_RS18095	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GSM99_RS18100	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GSM99_RS18105	ENOG4105DQR	SNARE associated Golgi
GSM99_RS18115	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GSM99_RS18120	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GSM99_RS18130	ENOG410631K	Membrane
GSM99_RS18135	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GSM99_RS18140	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GSM99_RS18145	ENOG4105XYF	acetyltransferase
GSM99_RS18155	ENOG4105MH2	YfcL protein
GSM99_RS18160	ENOG4108BPE	-transporting atpase
GSM99_RS18165	ENOG4105EJ9	Membrane
GSM99_RS18175	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GSM99_RS18180	ENOG4108DG9	Smr protein MutS2
GSM99_RS18185	ENOG4108BY2	phosphohistidine phosphatase
GSM99_RS18190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GSM99_RS18195	ENOG4105CHU	acetyl-coa acetyltransferase
GSM99_RS18200	ENOG4105KZW	UPF0381 protein
GSM99_RS18205	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GSM99_RS18210	ENOG410903C	(LipO)protein
GSM99_RS18215	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
GSM99_RS18235	ENOG4105R1U	AraC Family Transcriptional Regulator
GSM99_RS18245	ENOG4108J2R	molybdopterin oxidoreductase
GSM99_RS18250	ENOG4105QAX	Iron-sulfur
GSM99_RS18255	ENOG4108NWD	Cytochrome
GSM99_RS18270	ENOG4105ZUU	Transcriptional regulator
GSM99_RS18315	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GSM99_RS18330	ENOG4105CHR	reductase
GSM99_RS18340	ENOG4105VRT	cytoplasmic protein
GSM99_RS18345	ENOG4105D9N	nucleoside
GSM99_RS18350	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GSM99_RS18355	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GSM99_RS18360	ENOG4105EXN	Sulfate transport protein CysZ
GSM99_RS18370	ENOG4105C6T	cysteine synthase
GSM99_RS18375	ENOG4105KZ7	phosphocarrier protein hpr
GSM99_RS18380	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GSM99_RS18385	ENOG4105C5Y	PTS System
GSM99_RS18390	ENOG4105C6T	cysteine synthase
GSM99_RS18395	ENOG4108IJ6	ABC transporter
GSM99_RS18400	ENOG4105ECW	sulfate abc transporter
GSM99_RS18405	ENOG4108I5D	sulfate abc transporter
GSM99_RS18410	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
GSM99_RS18415	ENOG4105EZR	dyp-type peroxidase family protein
GSM99_RS18420	ENOG4105E7K	(LipO)protein
GSM99_RS18425	ENOG4108R6G	acetyltransferase
GSM99_RS18430	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GSM99_RS18440	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GSM99_RS18445	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GSM99_RS18450	ENOG4105N21	Membrane
GSM99_RS18455	ENOG4105CUT	histidyl-tRNA synthetase
GSM99_RS18460	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GSM99_RS18465	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GSM99_RS18475	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GSM99_RS18480	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GSM99_RS18485	ENOG4108JQB	penicillin-binding protein 1C
GSM99_RS18505	ENOG4105WVQ	Fe-S assembly protein IscX
GSM99_RS18510	ENOG4108ZIT	Ferredoxin, 2FE-2S
GSM99_RS18515	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GSM99_RS18520	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GSM99_RS18525	ENOG4108Z4V	iron-sulfur cluster assembly
GSM99_RS18530	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GSM99_RS18535	ENOG4105C3J	Cysteine desulfurase
GSM99_RS18540	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GSM99_RS18545	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GSM99_RS18565	ENOG4105D8G	Major Facilitator superfamily
GSM99_RS18570	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GSM99_RS18575	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GSM99_RS18585	ENOG4108YZA	Nitrogen regulatory protein pii
GSM99_RS18590	ENOG4105C4K	Nad synthetase
GSM99_RS18595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GSM99_RS18600	ENOG4108SKK	alpha helix protein
GSM99_RS18605	ENOG4107WP9	Histidine kinase
GSM99_RS18610	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GSM99_RS18615	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GSM99_RS18640	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GSM99_RS18675	ENOG4108V42	Type IV secretion system protein VirB8
GSM99_RS18935	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
GSM99_RS18940	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
GSM99_RS19010	ENOG4105ECI	YeeC-like protein
GSM99_RS19020	ENOG4105F6A	helicase
GSM99_RS19025	ENOG4105D85	methylase
GSM99_RS19035	ENOG4105EMU	Dehydrogenase
GSM99_RS19150	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GSM99_RS19170	ENOG4105EUV	Phenol 2-monooxygenase
GSM99_RS19310	ENOG4105C3F	Signal peptidase i
GSM99_RS19615	ENOG4105KT5	UmuD protein
GSM99_RS19620	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GSM99_RS19630	ENOG4108UUM	single-stranded DNA-binding protein
GSM99_RS19660	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
GSM99_RS19665	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
GSM99_RS19710	ENOG4105QAX	Iron-sulfur
GSM99_RS19720	ENOG4107QY8	reductase
GSM99_RS19730	ENOG4105C5H	ABC transporter
GSM99_RS19735	ENOG4105K4T	epimerase
GSM99_RS19745	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GSM99_RS19755	ENOG4105W1Y	Transcriptional regulator