locus-tag	class	description
AM438_RS00005	COG0596	Alpha beta hydrolase
AM438_RS00015	COG0716	FMN binding
AM438_RS00020	COG0735	belongs to the Fur family
AM438_RS00035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM438_RS00075	COG0363	glucosamine-6-phosphate deaminase activity
AM438_RS00080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM438_RS00085	COG1846	Transcriptional regulator
AM438_RS00085	COG1940	carbohydrate kinase activity
AM438_RS00135	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM438_RS00140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM438_RS00145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM438_RS00150	COG1702	phosphate starvation-inducible protein PhoH
AM438_RS00155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM438_RS00165	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM438_RS00175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM438_RS00200	COG0765	amino acid transport
AM438_RS00205	COG0765	amino acid transport
AM438_RS00210	COG1126	abc transporter atp-binding protein
AM438_RS00215	COG0495	leucyl-tRNA aminoacylation
AM438_RS00220	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AM438_RS00225	COG1466	dna polymerase III delta subunit
AM438_RS00230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM438_RS00240	COG0799	negative regulation of ribosome biogenesis
AM438_RS00245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM438_RS00250	COG0768	penicillin binding
AM438_RS00255	COG0772	Belongs to the SEDS family
AM438_RS00260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM438_RS00265	COG1686	Belongs to the peptidase S11 family
AM438_RS00275	COG0321	lipoyl(octanoyl) transferase activity
AM438_RS00280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM438_RS00285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM438_RS00295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM438_RS00305	COG1780	Probably involved in ribonucleotide reductase function
AM438_RS00320	COG4175	Glycine betaine
AM438_RS00325	COG4176	ABC-type proline glycine betaine transport system permease component
AM438_RS00330	COG2113	Glycine betaine
AM438_RS00335	COG1629	transport
AM438_RS00340	COG2814	Major facilitator Superfamily
AM438_RS00345	COG1846	Transcriptional regulator
AM438_RS00350	COG1335	isochorismatase
AM438_RS00355	COG2814	Major facilitator Superfamily
AM438_RS00365	COG1566	PFAM secretion protein HlyD family protein
AM438_RS00370	COG2814	Major facilitator Superfamily
AM438_RS00375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM438_RS00380	COG5160	protein modification by small protein removal
AM438_RS00385	COG3148	PFAM DTW domain containing protein
AM438_RS00390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM438_RS00390	COG1042	CoA-binding domain protein
AM438_RS00390	COG0045	succinate-CoA ligase (ADP-forming) activity
AM438_RS00395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM438_RS00400	COG5544	Lipoprotein
AM438_RS00430	COG0542	response to heat
AM438_RS00435	COG1496	oxidoreductase activity
AM438_RS00440	COG0564	pseudouridine synthase activity
AM438_RS00445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM438_RS00450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM438_RS00455	COG0077	Prephenate dehydratase
AM438_RS00455	COG1605	Chorismate mutase
AM438_RS00460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM438_RS00465	COG1605	Chorismate mutase
AM438_RS00465	COG0287	Prephenate dehydrogenase
AM438_RS00470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM438_RS00480	COG0335	large ribosomal subunit rRNA binding
AM438_RS00485	COG0336	Belongs to the RNA methyltransferase TrmD family
AM438_RS00495	COG0228	four-way junction DNA binding
AM438_RS00500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM438_RS00505	COG4137	Cytochrome C assembly protein
AM438_RS00510	COG4536	flavin adenine dinucleotide binding
AM438_RS00515	COG1854	S-ribosylhomocysteine lyase activity
AM438_RS00520	COG2918	glutathione biosynthetic process
AM438_RS00545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM438_RS00550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM438_RS00555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM438_RS00560	COG1546	Belongs to the CinA family
AM438_RS00565	COG2814	Major facilitator Superfamily
AM438_RS00570	COG0204	Acyl-transferase
AM438_RS00570	COG0318	PFAM AMP-dependent synthetase and ligase
AM438_RS00575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM438_RS00580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM438_RS00585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM438_RS00595	COG1073	alpha beta
AM438_RS00600	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM438_RS00605	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM438_RS00610	COG4774	siderophore transport
AM438_RS00615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM438_RS00625	COG3237	CsbD-like
AM438_RS00630	COG2991	Protein conserved in bacteria
AM438_RS00635	COG1477	protein flavinylation
AM438_RS00640	COG2871	sodium ion transport
AM438_RS00645	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM438_RS00650	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM438_RS00655	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM438_RS00660	COG1805	sodium ion transport
AM438_RS00665	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM438_RS00670	COG3034	peptidoglycan biosynthetic process
AM438_RS00675	COG0121	glutamine amidotransferase
AM438_RS00680	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM438_RS00685	COG1960	acyl-CoA dehydrogenase activity
AM438_RS00695	COG0583	DNA-binding transcription factor activity
AM438_RS00700	COG0583	DNA-binding transcription factor activity
AM438_RS00720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM438_RS00725	COG0189	ligase activity
AM438_RS00730	COG1678	Uncharacterized ACR, COG1678
AM438_RS00735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM438_RS00740	COG2805	Type II/IV secretion system protein
AM438_RS00745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM438_RS00750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM438_RS00755	COG0762	integral membrane protein
AM438_RS00760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM438_RS00765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM438_RS00770	COG4607	ABC-type enterochelin transport system periplasmic component
AM438_RS00780	COG2066	Belongs to the glutaminase family
AM438_RS00785	COG3171	Protein conserved in bacteria
AM438_RS00795	COG1194	a g-specific adenine glycosylase
AM438_RS00800	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AM438_RS00805	COG0741	lytic transglycosylase activity
AM438_RS00815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM438_RS00870	COG5290	Psort location Cytoplasmic, score
AM438_RS00960	COG1196	nuclear chromosome segregation
AM438_RS00985	COG1982	Orn Lys Arg decarboxylase major
AM438_RS00990	COG0531	amino acid
AM438_RS00995	COG1309	transcriptional regulator
AM438_RS01045	COG2274	protein secretion by the type I secretion system
AM438_RS01080	COG3708	Transcriptional regulator
AM438_RS01080	COG2207	Transcriptional regulator
AM438_RS01145	COG1263	PTS System
AM438_RS01145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS01150	COG1554	hydrolase, family 65, central catalytic
AM438_RS01155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM438_RS01225	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM438_RS01230	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM438_RS01240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM438_RS01255	COG3539	Fimbrial protein
AM438_RS01275	COG3188	usher protein
AM438_RS01285	COG3539	Fimbrial protein
AM438_RS01290	COG0582	viral genome integration into host DNA
AM438_RS01310	COG3539	Fimbrial protein
AM438_RS01315	COG3539	Fimbrial protein
AM438_RS01320	COG3121	Chaperone
AM438_RS01325	COG3188	usher protein
AM438_RS01330	COG3539	Fimbrial protein
AM438_RS01335	COG1234	tRNA 3'-trailer cleavage
AM438_RS01350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM438_RS01355	COG1846	Transcriptional regulator
AM438_RS01370	COG3104	oligopeptide transport
AM438_RS01375	COG2314	TM2 domain
AM438_RS01385	COG0126	phosphoglycerate kinase activity
AM438_RS01390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM438_RS01395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM438_RS01410	COG2814	Major facilitator Superfamily
AM438_RS01415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM438_RS01420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM438_RS01425	COG0019	diaminopimelate decarboxylase activity
AM438_RS01435	COG4264	IucA IucC family
AM438_RS01445	COG1120	ATPase activity
AM438_RS01450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM438_RS01460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM438_RS01465	COG0328	RNA-DNA hybrid ribonuclease activity
AM438_RS01470	COG2226	methyltransferase
AM438_RS01475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM438_RS01480	COG0741	lytic transglycosylase activity
AM438_RS01480	COG1388	LysM domain
AM438_RS01485	COG3961	Belongs to the TPP enzyme family
AM438_RS01490	COG0471	metal ion transport
AM438_RS01495	COG0148	phosphopyruvate hydratase activity
AM438_RS01500	COG0504	CTP synthase activity
AM438_RS01510	COG3956	TIGRFAM MazG family protein
AM438_RS01515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM438_RS01520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM438_RS01530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM438_RS01540	COG0316	Belongs to the HesB IscA family
AM438_RS01545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM438_RS01550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM438_RS01555	COG1643	Atp-dependent helicase
AM438_RS01560	COG1489	DNA binding
AM438_RS01580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM438_RS01585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM438_RS01590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM438_RS01595	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM438_RS01605	COG3851	Histidine kinase
AM438_RS01610	COG2271	Major facilitator Superfamily
AM438_RS01615	COG1840	ABC-type Fe3 transport system, periplasmic component
AM438_RS01625	COG3842	ATPase activity
AM438_RS01630	COG3048	D-serine ammonia-lyase activity
AM438_RS01635	COG2610	gluconate transmembrane transporter activity
AM438_RS01640	COG0583	DNA-binding transcription factor activity
AM438_RS01645	COG0754	glutathionylspermidine amidase activity
AM438_RS01670	COG2963	transposase activity
AM438_RS01685	COG4633	Protein conserved in bacteria
AM438_RS01700	COG2837	iron assimilation
AM438_RS01710	COG0243	molybdopterin cofactor binding
AM438_RS01715	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS01730	COG0501	Belongs to the peptidase M48B family
AM438_RS01740	COG0477	Major facilitator Superfamily
AM438_RS01745	COG0842	Transport permease protein
AM438_RS01750	COG1131	(ABC) transporter
AM438_RS01755	COG0288	reversible hydration of carbon dioxide
AM438_RS01765	COG2132	Multicopper oxidase
AM438_RS01800	COG5441	Belongs to the UPF0261 family
AM438_RS01805	COG5564	TIM-barrel signal transduction protein
AM438_RS01810	COG0673	inositol 2-dehydrogenase activity
AM438_RS01815	COG0534	Mate efflux family protein
AM438_RS01825	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM438_RS01830	COG3069	C4-dicarboxylate transmembrane transporter activity
AM438_RS01840	COG0523	cobalamin synthesis protein
AM438_RS01845	COG2879	small protein
AM438_RS01850	COG1966	Carbon starvation protein
AM438_RS01855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM438_RS01860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AM438_RS01870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM438_RS01885	COG3264	Mechanosensitive ion channel
AM438_RS01885	COG1196	nuclear chromosome segregation
AM438_RS01890	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM438_RS01895	COG1309	transcriptional regulator
AM438_RS01900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM438_RS01905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM438_RS01925	COG1946	Acyl-CoA thioesterase
AM438_RS01930	COG0004	ammonium transporteR
AM438_RS01935	COG0347	Belongs to the P(II) protein family
AM438_RS01940	COG1132	(ABC) transporter
AM438_RS01945	COG1132	(ABC) transporter
AM438_RS01950	COG1522	sequence-specific DNA binding
AM438_RS01955	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM438_RS01960	COG0824	Thioesterase
AM438_RS01965	COG1596	polysaccharide export
AM438_RS01965	COG1555	photosystem II stabilization
AM438_RS01970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM438_RS01975	COG0776	regulation of translation
AM438_RS01980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM438_RS01985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM438_RS01990	COG0740	serine-type endopeptidase activity
AM438_RS01995	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM438_RS02000	COG0271	Belongs to the BolA IbaG family
AM438_RS02005	COG3056	Lipoprotein
AM438_RS02010	COG2223	nitrite transmembrane transporter activity
AM438_RS02015	COG0513	Belongs to the DEAD box helicase family
AM438_RS02025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM438_RS02030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM438_RS02035	COG1845	cytochrome c oxidase, subunit III
AM438_RS02040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM438_RS02045	COG0109	protoheme IX farnesyltransferase activity
AM438_RS02050	COG2814	Major facilitator Superfamily
AM438_RS02055	COG1666	GTP binding
AM438_RS02060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM438_RS02065	COG0693	protein deglycase activity
AM438_RS02080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM438_RS02080	COG0301	tRNA thio-modification
AM438_RS02090	COG0142	geranyltranstransferase activity
AM438_RS02095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM438_RS02100	COG1869	D-ribose catabolic process
AM438_RS02105	COG1129	ABC transporter
AM438_RS02110	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM438_RS02115	COG1879	ABC-type sugar transport system periplasmic component
AM438_RS02120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM438_RS02125	COG1609	Transcriptional regulator
AM438_RS02140	COG2824	Alkylphosphonate utilization operon protein PhnA
AM438_RS02150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM438_RS02155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM438_RS02160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM438_RS02160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM438_RS02165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM438_RS02170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM438_RS02175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM438_RS02180	COG1862	Preprotein translocase
AM438_RS02185	COG0343	queuine tRNA-ribosyltransferase activity
AM438_RS02190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM438_RS02195	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AM438_RS02200	COG0450	alkyl hydroperoxide reductase
AM438_RS02210	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS02215	COG2414	aldehyde ferredoxin oxidoreductase
AM438_RS02225	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS02230	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM438_RS02280	COG1114	Component of the transport system for branched-chain amino acids
AM438_RS02285	COG5002	protein histidine kinase activity
AM438_RS02295	COG0420	3'-5' exonuclease activity
AM438_RS02300	COG0419	ATPase involved in DNA repair
AM438_RS02320	COG0737	Belongs to the 5'-nucleotidase family
AM438_RS02325	COG3719	Belongs to the RNase T2 family
AM438_RS02330	COG0737	Belongs to the 5'-nucleotidase family
AM438_RS02340	COG2974	May be involved in recombination
AM438_RS02345	COG0425	Belongs to the sulfur carrier protein TusA family
AM438_RS02350	COG2391	methyltransferase activity
AM438_RS02355	COG0309	Hydrogenase expression formation protein (HypE)
AM438_RS02360	COG0409	Hydrogenase expression formation protein
AM438_RS02365	COG0298	carbon dioxide binding
AM438_RS02370	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM438_RS02375	COG1773	rubredoxin
AM438_RS02380	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM438_RS02385	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM438_RS02390	COG5557	Pfam Polysulphide reductase, NrfD
AM438_RS02395	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS02400	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM438_RS02405	COG0848	biopolymer transport protein
AM438_RS02410	COG0811	peptide transport
AM438_RS02415	COG0626	cystathionine gamma-synthase activity
AM438_RS02425	COG1979	alcohol dehydrogenase
AM438_RS02435	COG1388	LysM domain
AM438_RS02435	COG1470	cell adhesion involved in biofilm formation
AM438_RS02455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM438_RS02460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM438_RS02465	COG1047	Peptidyl-prolyl cis-trans
AM438_RS02470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM438_RS02475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM438_RS02480	COG0196	riboflavin kinase activity
AM438_RS02485	COG0268	Binds directly to 16S ribosomal RNA
AM438_RS02490	COG0583	DNA-binding transcription factor activity
AM438_RS02495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM438_RS02500	COG0484	heat shock protein binding
AM438_RS02505	COG0443	Heat shock 70 kDa protein
AM438_RS02510	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM438_RS02520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM438_RS02525	COG3022	response to hydroperoxide
AM438_RS02540	COG0083	homoserine kinase activity
AM438_RS02550	COG0745	RESPONSE REGULATOR receiver
AM438_RS02555	COG3045	CreA protein
AM438_RS02560	COG2207	Transcriptional regulator
AM438_RS02560	COG3708	Transcriptional regulator
AM438_RS02565	COG0406	alpha-ribazole phosphatase activity
AM438_RS02570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AM438_RS02575	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AM438_RS02580	COG0741	lytic transglycosylase activity
AM438_RS02585	COG0488	(ABC) transporter
AM438_RS02595	COG0675	Transposase, IS605 OrfB family
AM438_RS02605	COG1595	DNA-templated transcription, initiation
AM438_RS02615	COG4771	TonB-dependent receptor
AM438_RS02620	COG4178	(ABC) transporter
AM438_RS02625	COG0612	Peptidase, M16
AM438_RS02635	COG1902	pentaerythritol trinitrate reductase activity
AM438_RS02635	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM438_RS02640	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM438_RS02645	COG0586	Pfam SNARE associated Golgi protein
AM438_RS02650	COG4575	ribosome binding
AM438_RS02655	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM438_RS02665	COG2259	Doxx family
AM438_RS02670	COG0583	DNA-binding transcription factor activity
AM438_RS02675	COG1741	Belongs to the pirin family
AM438_RS02685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM438_RS02695	COG0792	nuclease activity
AM438_RS02700	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM438_RS02705	COG2823	Periplasmic or secreted lipoprotein
AM438_RS02710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM438_RS02715	COG0830	nickel cation binding
AM438_RS02720	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM438_RS02725	COG0804	urea catabolic process
AM438_RS02730	COG0832	Belongs to the urease beta subunit family
AM438_RS02735	COG0831	urea catabolic process
AM438_RS02740	COG0829	nickel cation binding
AM438_RS02745	COG2207	Transcriptional regulator
AM438_RS02750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM438_RS02755	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM438_RS02760	COG5002	protein histidine kinase activity
AM438_RS02760	COG0784	Response regulator, receiver
AM438_RS02760	COG2198	Histidine kinase
AM438_RS02765	COG0069	glutamate synthase activity
AM438_RS02765	COG0067	glutamate synthase
AM438_RS02765	COG0070	glutamate synthase
AM438_RS02770	COG0493	'glutamate synthase
AM438_RS02775	COG3069	C4-dicarboxylate transmembrane transporter activity
AM438_RS02780	COG1473	amidohydrolase
AM438_RS02790	COG2969	positive regulation of protein catabolic process
AM438_RS02795	COG0625	glutathione transferase activity
AM438_RS02800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM438_RS02805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM438_RS02810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM438_RS02815	COG3105	Protein conserved in bacteria
AM438_RS02820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM438_RS02825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM438_RS02845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM438_RS02850	COG5007	Belongs to the BolA IbaG family
AM438_RS02860	COG2854	intermembrane phospholipid transfer
AM438_RS02865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM438_RS02870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM438_RS02875	COG1127	ABC transporter
AM438_RS02880	COG0530	calcium, potassium:sodium antiporter activity
AM438_RS02885	COG0517	IMP dehydrogenase activity
AM438_RS02885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM438_RS02890	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM438_RS02895	COG3117	lipopolysaccharide transmembrane transporter activity
AM438_RS02900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM438_RS02905	COG1137	ATPase activity
AM438_RS02910	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM438_RS02915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM438_RS02925	COG1660	Displays ATPase and GTPase activities
AM438_RS02930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM438_RS02935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM438_RS02940	COG0312	modulator of DNA gyrase
AM438_RS02945	COG3028	Belongs to the UPF0307 family
AM438_RS02950	COG2732	(Barnase) inhibitor
AM438_RS02960	COG0312	modulator of DNA gyrase
AM438_RS02965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM438_RS02970	COG3164	Protein of unknown function
AM438_RS02975	COG1530	ribonuclease E activity
AM438_RS02980	COG0424	maF-like protein
AM438_RS02985	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM438_RS02990	COG1792	Involved in formation and maintenance of cell shape
AM438_RS02995	COG1077	Cell shape determining protein MreB Mrl
AM438_RS03000	COG0604	alcohol dehydrogenase
AM438_RS03005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM438_RS03010	COG0511	ligase activity, forming carbon-carbon bonds
AM438_RS03015	COG0439	Biotin carboxylase
AM438_RS03020	COG3924	membrane
AM438_RS03025	COG4145	pantothenate transmembrane transporter activity
AM438_RS03030	COG2264	protein methyltransferase activity
AM438_RS03035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM438_RS03040	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM438_RS03055	COG2807	transmembrane transport
AM438_RS03060	COG0584	glycerophosphoryl diester phosphodiesterase
AM438_RS03065	COG1653	transport
AM438_RS03075	COG0395	ABC-type sugar transport system, permease component
AM438_RS03080	COG3842	ATPase activity
AM438_RS03085	COG0501	Belongs to the peptidase M48B family
AM438_RS03090	COG1846	Transcriptional regulator
AM438_RS03095	COG2814	Major facilitator Superfamily
AM438_RS03105	COG1929	Belongs to the glycerate kinase type-1 family
AM438_RS03115	COG2177	Part of the ABC transporter FtsEX involved in
AM438_RS03120	COG2884	Cell division ATP-binding protein ftsE
AM438_RS03125	COG0552	protein localization to endoplasmic reticulum
AM438_RS03130	COG0742	ribosomal rna small subunit methyltransferase
AM438_RS03135	COG3776	membrane
AM438_RS03145	COG3714	YhhN family
AM438_RS03150	COG2217	Heavy metal translocating P-type atpase
AM438_RS03165	COG0425	Belongs to the sulfur carrier protein TusA family
AM438_RS03175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM438_RS03185	COG0247	lactate metabolic process
AM438_RS03195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM438_RS03200	COG2271	Major facilitator Superfamily
AM438_RS03205	COG0584	glycerophosphoryl diester phosphodiesterase
AM438_RS03210	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM438_RS03215	COG1053	succinate dehydrogenase
AM438_RS03220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM438_RS03225	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM438_RS03230	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM438_RS03235	COG2076	Multidrug Resistance protein
AM438_RS03240	COG0298	carbon dioxide binding
AM438_RS03245	COG0375	protein maturation
AM438_RS03250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM438_RS03255	COG3604	Transcriptional regulator
AM438_RS03270	COG2194	sulfuric ester hydrolase activity
AM438_RS03275	COG1304	FMN binding
AM438_RS03280	COG2181	nitrate reductase activity
AM438_RS03285	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM438_RS03290	COG1140	nitrate reductase beta subunit
AM438_RS03295	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM438_RS03300	COG2223	nitrite transmembrane transporter activity
AM438_RS03305	COG3850	Histidine kinase
AM438_RS03310	COG2197	response regulator
AM438_RS03315	COG0583	DNA-binding transcription factor activity
AM438_RS03350	COG0730	response to heat
AM438_RS03355	COG4770	biotin carboxylase activity
AM438_RS03360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM438_RS03365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AM438_RS03370	COG1914	H( )-stimulated, divalent metal cation uptake system
AM438_RS03405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM438_RS03410	COG1739	Uncharacterized protein family UPF0029
AM438_RS03415	COG0006	proline dipeptidase activity
AM438_RS03420	COG1024	Enoyl-CoA hydratase
AM438_RS03420	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM438_RS03425	COG0183	Belongs to the thiolase family
AM438_RS03435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM438_RS03450	COG0805	protein transport
AM438_RS03455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM438_RS03460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM438_RS03470	COG3165	ubiquinone biosynthetic process from chorismate
AM438_RS03475	COG2226	methyltransferase
AM438_RS03480	COG1322	Protein conserved in bacteria
AM438_RS03485	COG0586	Pfam SNARE associated Golgi protein
AM438_RS03490	COG2365	Tyrosine phosphatase family
AM438_RS03500	COG3753	Protein conserved in bacteria
AM438_RS03510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM438_RS03515	COG0583	DNA-binding transcription factor activity
AM438_RS03525	COG0025	NhaP-type Na H and K H
AM438_RS03530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM438_RS03535	COG2252	PERMEase
AM438_RS03555	COG0440	acetolactate synthase activity
AM438_RS03560	COG0028	Belongs to the TPP enzyme family
AM438_RS03580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS03580	COG1263	PTS System
AM438_RS03585	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM438_RS03595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM438_RS03600	COG1349	DNA-binding transcription factor activity
AM438_RS03605	COG1690	Belongs to the RtcB family
AM438_RS03610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM438_RS03625	COG0675	Transposase, IS605 OrfB family
AM438_RS03645	COG3157	Type VI secretion system effector, Hcp
AM438_RS03670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM438_RS03675	COG0795	lipopolysaccharide-transporting ATPase activity
AM438_RS03680	COG0795	lipopolysaccharide-transporting ATPase activity
AM438_RS03685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM438_RS03690	COG2927	DNA polymerase III (CHI subunit)
AM438_RS03695	COG0525	valine-tRNA ligase activity
AM438_RS03700	COG0456	acetyltransferase
AM438_RS03715	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AM438_RS03720	COG0675	Transposase, IS605 OrfB family
AM438_RS03725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM438_RS03735	COG0540	Belongs to the ATCase OTCase family
AM438_RS03740	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AM438_RS03745	COG0251	oxidation-reduction process
AM438_RS03755	COG1328	CTP reductase activity
AM438_RS03760	COG0602	queuosine metabolic process
AM438_RS03785	COG2827	Endonuclease containing a URI domain
AM438_RS03790	COG3153	acetyltransferase
AM438_RS03795	COG3154	lipid carrier protein
AM438_RS03800	COG0826	peptidase U32
AM438_RS03805	COG0826	peptidase U32
AM438_RS03810	COG3539	Fimbrial protein
AM438_RS03815	COG3539	Fimbrial protein
AM438_RS03820	COG3539	Fimbrial protein
AM438_RS03825	COG3188	usher protein
AM438_RS03830	COG3121	Chaperone
AM438_RS03835	COG3539	Fimbrial protein
AM438_RS03850	COG1566	PFAM secretion protein HlyD family protein
AM438_RS03855	COG3275	phosphorelay sensor kinase activity
AM438_RS03880	COG2271	Major facilitator Superfamily
AM438_RS03885	COG0251	oxidation-reduction process
AM438_RS03895	COG2964	Protein conserved in bacteria
AM438_RS03900	COG0513	Belongs to the DEAD box helicase family
AM438_RS03910	COG1185	polyribonucleotide nucleotidyltransferase activity
AM438_RS03915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM438_RS03920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM438_RS03925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM438_RS03930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM438_RS03930	COG3064	Membrane
AM438_RS03935	COG0195	Participates in both transcription termination and antitermination
AM438_RS03940	COG0779	Required for maturation of 30S ribosomal subunits
AM438_RS03955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM438_RS03960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM438_RS03965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM438_RS03970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM438_RS03975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM438_RS03980	COG1534	Rna-binding protein
AM438_RS03990	COG2027	D-alanyl-D-alanine carboxypeptidase
AM438_RS03995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM438_RS04000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM438_RS04005	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM438_RS04010	COG0142	geranyltranstransferase activity
AM438_RS04025	COG3423	Transcriptional regulator
AM438_RS04030	COG0039	L-malate dehydrogenase activity
AM438_RS04035	COG1438	arginine binding
AM438_RS04040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM438_RS04045	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM438_RS04050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM438_RS04070	COG2105	PFAM AIG2 family protein
AM438_RS04075	COG2911	Protein conserved in bacteria
AM438_RS04080	COG0729	surface antigen
AM438_RS04085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM438_RS04090	COG1253	flavin adenine dinucleotide binding
AM438_RS04100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM438_RS04110	COG0545	Peptidyl-prolyl cis-trans isomerase
AM438_RS04115	COG1012	belongs to the aldehyde dehydrogenase family
AM438_RS04125	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM438_RS04130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM438_RS04135	COG0254	rRNA binding
AM438_RS04140	COG3061	Opacity-associated protein A
AM438_RS04145	COG0359	binds to the 23S rRNA
AM438_RS04150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM438_RS04155	COG2965	DNA replication, synthesis of RNA primer
AM438_RS04160	COG0360	Binds together with S18 to 16S ribosomal RNA
AM438_RS04165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM438_RS04170	COG0557	exoribonuclease II activity
AM438_RS04175	COG1959	2 iron, 2 sulfur cluster binding
AM438_RS04180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM438_RS04185	COG0330	HflC and HflK could
AM438_RS04190	COG0330	HflC and HflK could
AM438_RS04195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM438_RS04200	COG1923	regulation of RNA biosynthetic process
AM438_RS04205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM438_RS04210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM438_RS04215	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM438_RS04220	COG0802	atpase or kinase
AM438_RS04225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM438_RS04250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM438_RS04255	COG1162	GTPase activity
AM438_RS04260	COG0688	phosphatidylethanolamine metabolic process
AM438_RS04265	COG3264	Mechanosensitive ion channel
AM438_RS04265	COG1511	domain protein
AM438_RS04275	COG3539	Fimbrial protein
AM438_RS04280	COG3121	Chaperone
AM438_RS04285	COG3188	usher protein
AM438_RS04295	COG0561	phosphatase activity
AM438_RS04300	COG2267	carboxylic ester hydrolase activity
AM438_RS04315	COG2050	protein possibly involved in aromatic compounds catabolism
AM438_RS04320	COG2962	Rard protein
AM438_RS04330	COG0210	DNA helicase
AM438_RS04335	COG1011	Hydrolase
AM438_RS04350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM438_RS04355	COG5567	small periplasmic lipoprotein
AM438_RS04360	COG1965	Belongs to the frataxin family
AM438_RS04370	COG0181	hydroxymethylbilane synthase activity
AM438_RS04380	COG2959	enzyme of heme biosynthesis
AM438_RS04385	COG3071	HemY protein
AM438_RS04415	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM438_RS04425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM438_RS04430	COG2244	polysaccharide biosynthetic process
AM438_RS04435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM438_RS04440	COG0456	acetyltransferase
AM438_RS04445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM438_RS04450	COG1088	dTDP-glucose 4,6-dehydratase activity
AM438_RS04455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM438_RS04460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM438_RS04470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM438_RS04475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM438_RS04480	COG3118	belongs to the thioredoxin family
AM438_RS04485	COG0513	Belongs to the DEAD box helicase family
AM438_RS04495	COG0210	DNA helicase
AM438_RS04505	COG3041	Addiction module toxin RelE StbE family
AM438_RS04510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM438_RS04525	COG0129	dihydroxy-acid dehydratase activity
AM438_RS04535	COG3978	acetolactate synthase activity
AM438_RS04550	COG0606	chelatase, subunit chli
AM438_RS04555	COG3085	chromosome segregation
AM438_RS04560	COG0583	DNA-binding transcription factor activity
AM438_RS04600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM438_RS04610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM438_RS04615	COG0009	L-threonylcarbamoyladenylate synthase
AM438_RS04620	COG0551	DNA topoisomerase type I activity
AM438_RS04625	COG0758	DNA mediated transformation
AM438_RS04630	COG0242	peptide deformylase activity
AM438_RS04635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM438_RS04640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM438_RS04640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM438_RS04645	COG0569	domain protein
AM438_RS04650	COG1970	mechanosensitive ion channel activity
AM438_RS04655	COG3036	rescue of stalled ribosome
AM438_RS04660	COG0789	Transcriptional regulator
AM438_RS04665	COG0203	ribosomal protein L17
AM438_RS04675	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM438_RS04685	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM438_RS04690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM438_RS04695	COG0201	protein transport
AM438_RS04700	COG0200	Binds to the 23S rRNA
AM438_RS04705	COG1841	ribosomal large subunit assembly
AM438_RS04710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM438_RS04715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM438_RS04720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM438_RS04725	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM438_RS04730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM438_RS04735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM438_RS04740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM438_RS04745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM438_RS04750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM438_RS04755	COG0255	Belongs to the universal ribosomal protein uL29 family
AM438_RS04760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM438_RS04770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM438_RS04775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM438_RS04780	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM438_RS04785	COG0089	rRNA binding
AM438_RS04790	COG0088	Forms part of the polypeptide exit tunnel
AM438_RS04795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM438_RS04800	COG0051	transcription antitermination factor activity, RNA binding
AM438_RS04845	COG1072	(Pantothenic acid kinase))
AM438_RS04855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM438_RS04890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM438_RS04895	COG4206	TonB-dependent receptor
AM438_RS04900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM438_RS04915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM438_RS04925	COG0165	Argininosuccinate lyase
AM438_RS04930	COG0137	argininosuccinate synthase activity
AM438_RS04935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM438_RS04940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM438_RS04945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM438_RS04950	COG0028	Belongs to the TPP enzyme family
AM438_RS04970	COG0583	DNA-binding transcription factor activity
AM438_RS04975	COG0477	Major facilitator Superfamily
AM438_RS04985	COG1216	Glycosyl transferase, family 2
AM438_RS04990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM438_RS04995	COG2862	Uncharacterized protein family, UPF0114
AM438_RS05000	COG0527	aspartate kinase activity
AM438_RS05000	COG0460	homoserine dehydrogenase
AM438_RS05005	COG0626	cystathionine gamma-synthase activity
AM438_RS05010	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AM438_RS05015	COG0254	rRNA binding
AM438_RS05020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM438_RS05025	COG1609	Transcriptional regulator
AM438_RS05030	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM438_RS05035	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM438_RS05040	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM438_RS05045	COG1575	Belongs to the MenA family. Type 1 subfamily
AM438_RS05050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM438_RS05055	COG3074	FtsZ-dependent cytokinesis
AM438_RS05065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM438_RS05070	COG2814	Major facilitator Superfamily
AM438_RS05075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM438_RS05080	COG3152	Membrane
AM438_RS05090	COG0149	triose-phosphate isomerase activity
AM438_RS05095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM438_RS05100	COG0205	6-phosphofructokinase activity
AM438_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
AM438_RS05110	COG2944	sequence-specific DNA binding
AM438_RS05115	COG3678	ATP-independent chaperone mediated protein folding
AM438_RS05120	COG0745	RESPONSE REGULATOR receiver
AM438_RS05125	COG2205	protein histidine kinase activity
AM438_RS05130	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM438_RS05145	COG0110	maltose O-acetyltransferase activity
AM438_RS05175	COG1215	transferase activity, transferring glycosyl groups
AM438_RS05180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM438_RS05185	COG1216	Glycosyl transferase, family 2
AM438_RS05190	COG1045	serine acetyltransferase
AM438_RS05195	COG1045	serine acetyltransferase
AM438_RS05205	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AM438_RS05210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM438_RS05220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM438_RS05225	COG4942	peptidase
AM438_RS05230	COG2861	carbohydrate metabolic process
AM438_RS05235	COG1063	alcohol dehydrogenase
AM438_RS05240	COG0156	8-amino-7-oxononanoate synthase activity
AM438_RS05245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM438_RS05255	COG0859	PFAM glycosyl transferase family 9
AM438_RS05260	COG1216	Glycosyl transferase, family 2
AM438_RS05260	COG1442	glycosyl transferase family 8
AM438_RS05265	COG0859	PFAM glycosyl transferase family 9
AM438_RS05280	COG0438	transferase activity, transferring glycosyl groups
AM438_RS05285	COG0438	transferase activity, transferring glycosyl groups
AM438_RS05290	COG0859	PFAM glycosyl transferase family 9
AM438_RS05295	COG1519	Transferase
AM438_RS05305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM438_RS05310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM438_RS05325	COG0297	glycogen (starch) synthase activity
AM438_RS05335	COG0438	transferase activity, transferring glycosyl groups
AM438_RS05340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM438_RS05345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM438_RS05355	COG2003	Belongs to the UPF0758 family
AM438_RS05360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM438_RS05365	COG0756	dUTP diphosphatase activity
AM438_RS05370	COG1309	transcriptional regulator
AM438_RS05375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM438_RS05380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM438_RS05385	COG1561	YicC-like family, N-terminal region
AM438_RS05400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM438_RS05420	COG4106	trans-aconitate 2-methyltransferase activity
AM438_RS05425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM438_RS05430	COG0187	DNA topoisomerase II activity
AM438_RS05435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM438_RS05445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM438_RS05450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM438_RS05455	COG0594	ribonuclease P activity
AM438_RS05460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM438_RS05465	COG0706	membrane insertase activity
AM438_RS05470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM438_RS05475	COG4974	Belongs to the 'phage' integrase family
AM438_RS05580	COG0464	growth
AM438_RS05715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM438_RS05750	COG0789	Transcriptional regulator
AM438_RS05760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM438_RS05795	COG3550	peptidyl-serine autophosphorylation
AM438_RS05835	COG0583	DNA-binding transcription factor activity
AM438_RS05840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM438_RS05860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM438_RS05865	COG3383	formate dehydrogenase (NAD+) activity
AM438_RS05865	COG0243	molybdopterin cofactor binding
AM438_RS05870	COG0243	molybdopterin cofactor binding
AM438_RS05870	COG3383	formate dehydrogenase (NAD+) activity
AM438_RS05875	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS05880	COG2864	formate dehydrogenase
AM438_RS05885	COG3058	Necessary for formate dehydrogenase activity
AM438_RS05890	COG1921	L-seryl-tRNASec selenium transferase activity
AM438_RS05895	COG3276	selenocysteine insertion sequence binding
AM438_RS05900	COG1368	sulfuric ester hydrolase activity
AM438_RS05905	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM438_RS05910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM438_RS05915	COG3706	GGDEF domain
AM438_RS05925	COG0457	Tetratricopeptide repeat
AM438_RS05935	COG1215	transferase activity, transferring glycosyl groups
AM438_RS05945	COG1940	carbohydrate kinase activity
AM438_RS05955	COG3111	PFAM Bacterial OB fold (BOF) protein
AM438_RS06015	COG1288	antiporter activity
AM438_RS06025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM438_RS06045	COG0675	Transposase, IS605 OrfB family
AM438_RS06055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM438_RS06060	COG1840	ABC-type Fe3 transport system, periplasmic component
AM438_RS06065	COG1178	ABC-type Fe3 transport system permease component
AM438_RS06070	COG3842	ATPase activity
AM438_RS06150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM438_RS06155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM438_RS06160	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM438_RS06165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM438_RS06170	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM438_RS06175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM438_RS06180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM438_RS06185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM438_RS06195	COG0356	it plays a direct role in the translocation of protons across the membrane
AM438_RS06200	COG3312	ion transport
AM438_RS06205	COG0357	Ribosomal RNA small subunit methyltransferase G
AM438_RS06210	COG0445	tRNA wobble uridine modification
AM438_RS06215	COG0716	FMN binding
AM438_RS06220	COG1522	sequence-specific DNA binding
AM438_RS06225	COG2502	aspartate--ammonia ligase
AM438_RS06230	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM438_RS06235	COG0714	Associated with various cellular activities
AM438_RS06240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM438_RS06245	COG0477	Major facilitator Superfamily
AM438_RS06250	COG2186	Transcriptional regulator
AM438_RS06275	COG0247	lactate metabolic process
AM438_RS06280	COG1139	Iron-sulfur cluster binding protein
AM438_RS06285	COG1556	Lactate utilization protein
AM438_RS06290	COG2194	sulfuric ester hydrolase activity
AM438_RS06295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM438_RS06300	COG3162	membrane
AM438_RS06305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM438_RS06310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM438_RS06315	COG2258	MOSC domain
AM438_RS06325	COG0675	Transposase, IS605 OrfB family
AM438_RS06330	COG0180	Tryptophanyl-tRNA synthetase
AM438_RS06335	COG0546	phosphoglycolate phosphatase activity
AM438_RS06340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM438_RS06355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM438_RS06360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM438_RS06365	COG4796	Type ii and iii secretion system protein
AM438_RS06385	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM438_RS06395	COG0494	nUDIX hydrolase
AM438_RS06405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM438_RS06410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM438_RS06415	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM438_RS06420	COG1741	Belongs to the pirin family
AM438_RS06435	COG2081	HI0933 family
AM438_RS06440	COG0306	phosphate transporter
AM438_RS06450	COG0589	response to stress
AM438_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
AM438_RS06465	COG0742	ribosomal rna small subunit methyltransferase
AM438_RS06550	COG3501	Rhs element vgr protein
AM438_RS06565	COG3122	Protein conserved in bacteria
AM438_RS06570	COG0564	pseudouridine synthase activity
AM438_RS06575	COG1278	Cold shock
AM438_RS06580	COG1737	Transcriptional regulator
AM438_RS06585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS06585	COG1263	PTS System
AM438_RS06590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM438_RS06595	COG0733	neurotransmitter:sodium symporter activity
AM438_RS06600	COG3383	formate dehydrogenase (NAD+) activity
AM438_RS06605	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM438_RS06615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM438_RS06620	COG2731	YhcH YjgK YiaL family protein
AM438_RS06625	COG1737	Transcriptional regulator
AM438_RS06645	COG1285	pathogenesis
AM438_RS06650	COG2211	Major facilitator Superfamily
AM438_RS06660	COG1609	Transcriptional regulator
AM438_RS06665	COG3302	dmso reductase anchor subunit
AM438_RS06670	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS06675	COG0243	molybdopterin cofactor binding
AM438_RS06695	COG4604	ABC transporter, ATP-binding protein
AM438_RS06700	COG4605	iron ion homeostasis
AM438_RS06705	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM438_RS06710	COG4607	ABC-type enterochelin transport system periplasmic component
AM438_RS06715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM438_RS06720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM438_RS06725	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM438_RS06730	COG1917	Cupin 2, conserved barrel domain protein
AM438_RS06730	COG2169	Transcriptional regulator
AM438_RS06735	COG1486	melibiose metabolic process
AM438_RS06740	COG3394	polysaccharide catabolic process
AM438_RS06755	COG1073	alpha beta
AM438_RS06755	COG2226	methyltransferase
AM438_RS06760	COG0747	negative chemotaxis
AM438_RS06765	COG0601	transmembrane transport
AM438_RS06780	COG1124	(ABC) transporter
AM438_RS06800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM438_RS06840	COG3189	MarR family transcriptional regulator
AM438_RS06845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM438_RS06850	COG1349	DNA-binding transcription factor activity
AM438_RS06855	COG0705	Rhomboid family
AM438_RS06860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM438_RS06865	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM438_RS06865	COG0316	Belongs to the HesB IscA family
AM438_RS06870	COG1040	competence protein
AM438_RS06875	COG2267	carboxylic ester hydrolase activity
AM438_RS06890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM438_RS06895	COG1918	ferrous iron import across plasma membrane
AM438_RS06915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM438_RS06920	COG2252	PERMEase
AM438_RS06930	COG0736	holo-[acyl-carrier-protein] synthase activity
AM438_RS06940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM438_RS06945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM438_RS06950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM438_RS06955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM438_RS06970	COG1136	(ABC) transporter
AM438_RS06995	COG0765	amino acid transport
AM438_RS07000	COG0765	amino acid transport
AM438_RS07005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM438_RS07010	COG0704	Plays a role in the regulation of phosphate uptake
AM438_RS07020	COG0581	inorganic phosphate transmembrane transporter activity
AM438_RS07025	COG0573	inorganic phosphate transmembrane transporter activity
AM438_RS07030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM438_RS07045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM438_RS07050	COG2183	response to ionizing radiation
AM438_RS07090	COG1217	gtp-binding protein TYPA
AM438_RS07110	COG3550	peptidyl-serine autophosphorylation
AM438_RS07115	COG1011	Hydrolase
AM438_RS07120	COG1490	D-aminoacyl-tRNA deacylase activity
AM438_RS07125	COG0456	acetyltransferase
AM438_RS07130	COG1187	pseudouridine synthase activity
AM438_RS07140	COG2982	Protein involved in outer membrane biogenesis
AM438_RS07150	COG2233	PERMEase
AM438_RS07155	COG0786	glutamate:sodium symporter activity
AM438_RS07160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM438_RS07165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM438_RS07170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM438_RS07175	COG1758	RNA polymerase activity
AM438_RS07180	COG0194	GDP metabolic process
AM438_RS07185	COG2860	membrane
AM438_RS07190	COG0823	Involved in the tonB-independent uptake of proteins
AM438_RS07215	COG0751	glycine-tRNA ligase activity
AM438_RS07220	COG0752	glycyl-tRNA synthetase alpha subunit
AM438_RS07225	COG2818	Glycosylase
AM438_RS07230	COG3977	Valine--pyruvate aminotransferase
AM438_RS07235	COG2985	domain, Protein
AM438_RS07235	COG0569	domain protein
AM438_RS07240	COG5645	(Lipo)protein
AM438_RS07255	COG2831	hemolysin activation secretion protein
AM438_RS07260	COG0747	negative chemotaxis
AM438_RS07265	COG0601	transmembrane transport
AM438_RS07270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM438_RS07275	COG0444	Belongs to the ABC transporter superfamily
AM438_RS07280	COG4608	Belongs to the ABC transporter superfamily
AM438_RS07285	COG3210	domain, Protein
AM438_RS07290	COG2200	EAL domain
AM438_RS07290	COG2199	diguanylate cyclase activity
AM438_RS07300	COG1942	4-Oxalocrotonate Tautomerase
AM438_RS07305	COG1295	ribonuclease BN
AM438_RS07315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM438_RS07320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM438_RS07335	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM438_RS07340	COG0746	molybdenum cofactor guanylyltransferase activity
AM438_RS07345	COG3084	Protein conserved in bacteria
AM438_RS07350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM438_RS07355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM438_RS07365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM438_RS07365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM438_RS07370	COG0242	peptide deformylase activity
AM438_RS07380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM438_RS07390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM438_RS07395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM438_RS07400	COG1765	OsmC-like protein
AM438_RS07405	COG3954	Phosphoribulokinase
AM438_RS07410	COG3089	Belongs to the UPF0270 family
AM438_RS07415	COG0429	hydrolase of the alpha beta-hydrolase fold
AM438_RS07430	COG0840	transmembrane signaling receptor activity
AM438_RS07435	COG0840	transmembrane signaling receptor activity
AM438_RS07440	COG0840	transmembrane signaling receptor activity
AM438_RS07445	COG0488	(ABC) transporter
AM438_RS07450	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM438_RS07460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM438_RS07465	COG1047	Peptidyl-prolyl cis-trans
AM438_RS07470	COG2900	Belongs to the SlyX family
AM438_RS07475	COG0545	Peptidyl-prolyl cis-trans isomerase
AM438_RS07485	COG2964	Protein conserved in bacteria
AM438_RS07490	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM438_RS07495	COG2923	Belongs to the DsrF TusC family
AM438_RS07505	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM438_RS07510	COG0049	tRNA binding
AM438_RS07515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM438_RS07530	COG0250	Participates in transcription elongation, termination and antitermination
AM438_RS07535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM438_RS07540	COG0081	regulation of translation
AM438_RS07545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM438_RS07550	COG0222	ribosome binding
AM438_RS07555	COG0085	RNA polymerase activity
AM438_RS07560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM438_RS07565	COG5464	transposase or invertase
AM438_RS07575	COG2022	thiamine diphosphate biosynthetic process
AM438_RS07580	COG2104	thiamine diphosphate biosynthetic process
AM438_RS07585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM438_RS07590	COG0352	thiamine-phosphate diphosphorylase activity
AM438_RS07595	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM438_RS07605	COG2816	NAD+ diphosphatase activity
AM438_RS07610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM438_RS07615	COG1515	deoxyribonuclease V activity
AM438_RS07620	COG3068	Protein conserved in bacteria
AM438_RS07635	COG0151	Belongs to the GarS family
AM438_RS07640	COG0138	bifunctional purine biosynthesis protein purh
AM438_RS07670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM438_RS07680	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM438_RS07685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM438_RS07690	COG2224	Isocitrate lyase
AM438_RS07700	COG0800	Aldolase
AM438_RS07705	COG0129	dihydroxy-acid dehydratase activity
AM438_RS07715	COG1410	methionine synthase
AM438_RS07715	COG0646	methionine synthase
AM438_RS07730	COG0527	aspartate kinase activity
AM438_RS07735	COG0166	Belongs to the GPI family
AM438_RS07740	COG3161	chorismate lyase activity
AM438_RS07745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM438_RS07750	COG2937	Belongs to the GPAT DAPAT family
AM438_RS07755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM438_RS07760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM438_RS07765	COG0735	belongs to the Fur family
AM438_RS07775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM438_RS07780	COG0814	amino acid
AM438_RS07790	COG1448	Aminotransferase
AM438_RS07810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM438_RS07835	COG1177	transmembrane transport
AM438_RS07855	COG3539	Fimbrial protein
AM438_RS07860	COG3188	usher protein
AM438_RS07880	COG2873	o-acetylhomoserine
AM438_RS07915	COG1454	alcohol dehydrogenase
AM438_RS07915	COG1012	belongs to the aldehyde dehydrogenase family
AM438_RS07920	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM438_RS07930	COG1882	Formate acetyltransferase
AM438_RS07935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM438_RS07945	COG4869	propanediol catabolic process
AM438_RS07970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM438_RS07985	COG0789	Transcriptional regulator
AM438_RS08025	COG2207	Transcriptional regulator
AM438_RS08070	COG4790	Type iii secretion
AM438_RS08115	COG0157	Belongs to the NadC ModD family
AM438_RS08120	COG0500	methyltransferase
AM438_RS08125	COG1120	ATPase activity
AM438_RS08130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM438_RS08135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM438_RS08140	COG1609	Transcriptional regulator
AM438_RS08145	COG3265	gluconokinase activity
AM438_RS08150	COG2610	gluconate transmembrane transporter activity
AM438_RS08175	COG2992	FlgJ-related protein
AM438_RS08195	COG2137	regulation of response to DNA damage stimulus
AM438_RS08200	COG3397	chitin binding
AM438_RS08220	COG1024	Enoyl-CoA hydratase
AM438_RS08225	COG0318	PFAM AMP-dependent synthetase and ligase
AM438_RS08230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM438_RS08235	COG1960	acyl-CoA dehydrogenase activity
AM438_RS08255	COG0644	oxidoreductase
AM438_RS08260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM438_RS08265	COG2271	Major facilitator Superfamily
AM438_RS08270	COG2255	four-way junction helicase activity
AM438_RS08285	COG1704	LemA family
AM438_RS08290	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM438_RS08310	COG0305	Participates in initiation and elongation during chromosome replication
AM438_RS08360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM438_RS08390	COG1982	Orn Lys Arg decarboxylase major
AM438_RS08410	COG3059	membrane
AM438_RS08420	COG2801	Transposase and inactivated derivatives
AM438_RS08490	COG2375	cellular response to nickel ion
AM438_RS08490	COG1132	(ABC) transporter
AM438_RS08510	COG3433	isochorismatase activity
AM438_RS08510	COG2226	methyltransferase
AM438_RS08510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM438_RS08520	COG2814	Major facilitator Superfamily
AM438_RS08525	COG4771	TonB-dependent receptor
AM438_RS08755	COG1309	transcriptional regulator
AM438_RS08760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM438_RS08775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM438_RS08780	COG0459	protein refolding
AM438_RS08790	COG0675	Transposase, IS605 OrfB family
AM438_RS08800	COG0702	epimerase
AM438_RS08835	COG3188	usher protein
AM438_RS08855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM438_RS08860	COG0698	ribose 5-phosphate isomerase
AM438_RS08865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM438_RS08870	COG0651	ATP synthesis coupled electron transport
AM438_RS08875	COG0650	Formate hydrogenlyase subunit 4
AM438_RS08880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM438_RS08885	COG4237	Hydrogenase 4 membrane
AM438_RS08890	COG0651	ATP synthesis coupled electron transport
AM438_RS08895	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM438_RS08895	COG3261	NADH dehydrogenase
AM438_RS08900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM438_RS08905	COG3260	NADH ubiquinone oxidoreductase 20
AM438_RS08915	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM438_RS08920	COG1216	Glycosyl transferase, family 2
AM438_RS08935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM438_RS08955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM438_RS08960	COG1328	CTP reductase activity
AM438_RS08965	COG3726	membrane protein affecting hemolysin expression
AM438_RS08970	COG0560	Phosphoserine phosphatase
AM438_RS08990	COG2382	esterase
AM438_RS09000	COG0675	Transposase, IS605 OrfB family
AM438_RS09010	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM438_RS09025	COG2813	Specifically methylates the guanine in position
AM438_RS09045	COG1401	restriction endodeoxyribonuclease activity
AM438_RS09060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM438_RS09070	COG4667	esterase of the alpha-beta hydrolase superfamily
AM438_RS09075	COG0084	hydrolase, TatD family'
AM438_RS09080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM438_RS09085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM438_RS09090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AM438_RS09095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM438_RS09100	COG0813	purine-nucleoside phosphorylase activity
AM438_RS09105	COG2851	Citrate transporter
AM438_RS09115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM438_RS09120	COG0469	pyruvate kinase activity
AM438_RS09125	COG2271	Major facilitator Superfamily
AM438_RS09135	COG4191	Histidine kinase
AM438_RS09145	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM438_RS09145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM438_RS09145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM438_RS09150	COG1461	Dihydroxyacetone kinase
AM438_RS09155	COG2376	Dihydroxyacetone kinase
AM438_RS09210	COG1358	cellular component organization or biogenesis
AM438_RS09260	COG0840	transmembrane signaling receptor activity
AM438_RS09265	COG0840	transmembrane signaling receptor activity
AM438_RS09270	COG0583	DNA-binding transcription factor activity
AM438_RS09275	COG0243	molybdopterin cofactor binding
AM438_RS09280	COG1271	oxidase subunit
AM438_RS09285	COG1294	oxidase, subunit
AM438_RS09295	COG3781	membrane
AM438_RS09315	COG0358	DNA primase activity
AM438_RS09320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM438_RS09330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM438_RS09335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AM438_RS09355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM438_RS09360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM438_RS09365	COG0617	tRNA 3'-terminal CCA addition
AM438_RS09370	COG4991	sh3 domain protein
AM438_RS09375	COG3025	triphosphatase activity
AM438_RS09380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM438_RS09385	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM438_RS09385	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM438_RS09395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM438_RS09400	COG3384	dioxygenase
AM438_RS09405	COG0754	glutathionylspermidine amidase activity
AM438_RS09410	COG5463	Belongs to the UPF0441 family
AM438_RS09415	COG1538	Outer membrane efflux protein
AM438_RS09420	COG0494	nUDIX hydrolase
AM438_RS09425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM438_RS09430	COG3150	esterase
AM438_RS09435	COG0187	DNA topoisomerase II activity
AM438_RS09440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM438_RS09445	COG0204	Acyl-transferase
AM438_RS09450	COG2132	Multicopper oxidase
AM438_RS09470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM438_RS09475	COG2967	ApaG domain
AM438_RS09480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM438_RS09485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM438_RS09490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM438_RS09495	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM438_RS09500	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM438_RS09505	COG0564	pseudouridine synthase activity
AM438_RS09510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM438_RS09515	COG0417	DNA replication proofreading
AM438_RS09525	COG3311	Transcriptional regulator
AM438_RS09530	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AM438_RS09535	COG1178	ABC-type Fe3 transport system permease component
AM438_RS09540	COG4143	(ABC) transporter
AM438_RS09545	COG0494	nUDIX hydrolase
AM438_RS09555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM438_RS09560	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM438_RS09590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM438_RS09595	COG1025	Belongs to the peptidase M16 family
AM438_RS09600	COG1074	ATP-dependent DNA helicase activity
AM438_RS09605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM438_RS09610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM438_RS09610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM438_RS09615	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM438_RS09635	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM438_RS09640	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM438_RS09645	COG2166	iron-sulfur cluster assembly
AM438_RS09650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM438_RS09655	COG0583	DNA-binding transcription factor activity
AM438_RS09660	COG2363	Small membrane protein
AM438_RS09665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AM438_RS09670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM438_RS09675	COG1611	Belongs to the LOG family
AM438_RS09680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM438_RS09680	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM438_RS09690	COG3098	single-species biofilm formation
AM438_RS09700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS09700	COG1263	PTS System
AM438_RS09715	COG0716	FMN binding
AM438_RS09725	COG2171	N-acyltransferase activity
AM438_RS09730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM438_RS09740	COG0052	Belongs to the universal ribosomal protein uS2 family
AM438_RS09745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM438_RS09750	COG0528	UMP kinase activity
AM438_RS09755	COG0233	cytoplasmic translational termination
AM438_RS09760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM438_RS09765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM438_RS09770	COG0575	Belongs to the CDS family
AM438_RS09790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM438_RS09795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM438_RS09800	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM438_RS09805	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM438_RS09810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM438_RS09820	COG0825	malonyl-CoA metabolic process
AM438_RS09830	COG0037	tRNA processing
AM438_RS09835	COG4568	rho-dependent transcription termination
AM438_RS09840	COG3015	lipoprotein NlpE involved in copper resistance
AM438_RS09845	COG0442	prolyl-tRNA aminoacylation
AM438_RS09850	COG1720	tRNA m6t6A37 methyltransferase activity
AM438_RS09860	COG1464	Belongs to the NlpA lipoprotein family
AM438_RS09865	COG2011	ABC-type metal ion transport system permease component
AM438_RS09870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM438_RS09875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM438_RS09930	COG0602	queuosine metabolic process
AM438_RS09935	COG0720	synthase
AM438_RS09940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM438_RS09945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM438_RS09950	COG0175	sulfate reduction
AM438_RS09955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM438_RS09955	COG1648	precorrin-2 dehydrogenase activity
AM438_RS09960	COG0175	sulfate reduction
AM438_RS09965	COG2895	sulfate adenylyltransferase (ATP) activity
AM438_RS09980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM438_RS09985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM438_RS09990	COG0585	pseudouridine synthase activity
AM438_RS09995	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM438_RS10000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM438_RS10005	COG4942	peptidase
AM438_RS10005	COG1388	LysM domain
AM438_RS10015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM438_RS10025	COG3711	transcriptional antiterminator
AM438_RS10030	COG1263	PTS System
AM438_RS10030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS10030	COG2190	(PTS) system
AM438_RS10035	COG0613	PHP domain protein
AM438_RS10105	COG3539	Fimbrial protein
AM438_RS10130	COG0471	metal ion transport
AM438_RS10145	COG1335	isochorismatase
AM438_RS10150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM438_RS10155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM438_RS10165	COG0549	Belongs to the carbamate kinase family
AM438_RS10175	COG0583	DNA-binding transcription factor activity
AM438_RS10185	COG4589	Belongs to the CDS family
AM438_RS10200	COG4566	intracellular signal transduction
AM438_RS10220	COG2962	Rard protein
AM438_RS10225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM438_RS10230	COG0326	Molecular chaperone. Has ATPase activity
AM438_RS10235	COG0563	adenylate kinase activity
AM438_RS10240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM438_RS10245	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM438_RS10250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM438_RS10255	COG4651	solute:proton antiporter activity
AM438_RS10255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM438_RS10265	COG0675	Transposase, IS605 OrfB family
AM438_RS10270	COG0737	Belongs to the 5'-nucleotidase family
AM438_RS10280	COG3735	TraB family
AM438_RS10295	COG0789	Transcriptional regulator
AM438_RS10305	COG0330	HflC and HflK could
AM438_RS10310	COG3118	belongs to the thioredoxin family
AM438_RS10315	COG0300	oxidoreductase activity
AM438_RS10320	COG2755	lipolytic protein G-D-S-L family
AM438_RS10325	COG4181	ATPase activity
AM438_RS10330	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM438_RS10335	COG0668	transmembrane transport
AM438_RS10345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM438_RS10350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM438_RS10355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM438_RS10360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM438_RS10365	COG0215	cysteine-tRNA ligase activity
AM438_RS10370	COG1105	Belongs to the carbohydrate kinase PfkB family
AM438_RS10375	COG2501	S4 domain
AM438_RS10380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM438_RS10390	COG0582	viral genome integration into host DNA
AM438_RS10435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM438_RS10445	COG0640	Transcriptional regulator
AM438_RS10450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM438_RS10455	COG0384	phenazine biosynthesis protein PhzF
AM438_RS10475	COG0800	Aldolase
AM438_RS10480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM438_RS10495	COG3119	arylsulfatase activity
AM438_RS10500	COG0641	radical SAM
AM438_RS10505	COG1349	DNA-binding transcription factor activity
AM438_RS10515	COG2222	sugar isomerase
AM438_RS10520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS10525	COG3715	PTS system
AM438_RS10530	COG3716	PTS system mannose fructose sorbose family IID component
AM438_RS10535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM438_RS10535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM438_RS10540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM438_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
AM438_RS10590	COG3119	arylsulfatase activity
AM438_RS10600	COG5295	Hep Hag repeat protein
AM438_RS10615	COG3038	cytochrome b561
AM438_RS10620	COG2353	YceI-like domain
AM438_RS10625	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AM438_RS10630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM438_RS10645	COG1115	amino acid carrier protein
AM438_RS10655	COG1151	hydroxylamine reductase activity
AM438_RS10660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM438_RS10670	COG2239	Acts as a magnesium transporter
AM438_RS10675	COG3091	SprT-like family
AM438_RS10680	COG0640	Transcriptional regulator
AM438_RS10695	COG0457	Tetratricopeptide repeat
AM438_RS10695	COG3118	belongs to the thioredoxin family
AM438_RS10700	COG1215	transferase activity, transferring glycosyl groups
AM438_RS10710	COG1192	Involved in chromosome partitioning
AM438_RS10725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM438_RS10730	COG1166	arginine decarboxylase activity
AM438_RS10735	COG0010	Belongs to the arginase family
AM438_RS10745	COG3657	addiction module killer protein
AM438_RS10755	COG3066	DNA modification
AM438_RS10760	COG4533	DNA binding
AM438_RS10765	COG0066	3-isopropylmalate dehydratase activity
AM438_RS10770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM438_RS10775	COG0473	3-isopropylmalate dehydrogenase activity
AM438_RS10780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM438_RS10795	COG1022	Amp-dependent synthetase and ligase
AM438_RS10805	COG2001	Belongs to the MraZ family
AM438_RS10810	COG0275	rRNA processing
AM438_RS10820	COG0768	penicillin binding
AM438_RS10825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM438_RS10830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM438_RS10835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM438_RS10845	COG0772	Belongs to the SEDS family
AM438_RS10850	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM438_RS10855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM438_RS10865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM438_RS10870	COG0849	cell division
AM438_RS10880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AM438_RS10895	COG0653	protein targeting
AM438_RS10900	COG0789	Transcriptional regulator
AM438_RS10925	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM438_RS10930	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AM438_RS10935	COG0237	dephospho-CoA kinase activity
AM438_RS10945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM438_RS10950	COG4969	Belongs to the N-Me-Phe pilin family
AM438_RS10955	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM438_RS10960	COG2186	Transcriptional regulator
AM438_RS10965	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM438_RS10970	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM438_RS10975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM438_RS10980	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM438_RS10980	COG3064	Membrane
AM438_RS10980	COG1073	alpha beta
AM438_RS10995	COG3112	Uncharacterised protein family (UPF0231)
AM438_RS11005	COG1279	arginine transmembrane transporter activity
AM438_RS11025	COG0583	DNA-binding transcription factor activity
AM438_RS11030	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM438_RS11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM438_RS11045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM438_RS11055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM438_RS11065	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AM438_RS11070	COG3079	Belongs to the UPF0149 family
AM438_RS11075	COG0006	proline dipeptidase activity
AM438_RS11080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM438_RS11085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM438_RS11090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM438_RS11095	COG0509	glycine decarboxylation via glycine cleavage system
AM438_RS11100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM438_RS11100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM438_RS11110	COG0354	folic acid binding
AM438_RS11115	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM438_RS11130	COG0716	FMN binding
AM438_RS11140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM438_RS11145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM438_RS11155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM438_RS11225	COG2841	Protein conserved in bacteria
AM438_RS11230	COG4574	serine-type endopeptidase inhibitor activity
AM438_RS11235	COG0589	response to stress
AM438_RS11240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM438_RS11250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM438_RS11255	COG1085	galactose-1-phosphate uridylyltransferase
AM438_RS11260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM438_RS11265	COG2017	converts alpha-aldose to the beta-anomer
AM438_RS11270	COG1609	Transcriptional regulator
AM438_RS11280	COG4771	TonB-dependent receptor
AM438_RS11285	COG2819	hydrolase of the alpha beta superfamily
AM438_RS11295	COG3738	Protein conserved in bacteria
AM438_RS11300	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM438_RS11315	COG1556	Lactate utilization protein
AM438_RS11320	COG1139	Iron-sulfur cluster binding protein
AM438_RS11325	COG0247	lactate metabolic process
AM438_RS11330	COG1620	l-lactate permease
AM438_RS11335	COG2814	Major facilitator Superfamily
AM438_RS11340	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM438_RS11355	COG0579	oxidoreductase
AM438_RS11415	COG3210	domain, Protein
AM438_RS11420	COG2831	hemolysin activation secretion protein
AM438_RS11440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM438_RS11445	COG0732	type I restriction modification DNA specificity domain
AM438_RS11450	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM438_RS11455	COG1674	ftsk spoiiie
AM438_RS11455	COG3107	peptidoglycan biosynthetic process
AM438_RS11475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM438_RS11480	COG2867	negative regulation of translational initiation
AM438_RS11485	COG2914	Belongs to the UPF0125 (RnfH) family
AM438_RS11495	COG0497	DNA recombination
AM438_RS11500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM438_RS11505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM438_RS11510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM438_RS11520	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AM438_RS11525	COG0513	Belongs to the DEAD box helicase family
AM438_RS11530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM438_RS11535	COG1595	DNA-templated transcription, initiation
AM438_RS11540	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM438_RS11545	COG3026	antisigma factor binding
AM438_RS11550	COG3086	response to oxidative stress
AM438_RS11555	COG0481	GTPase activity
AM438_RS11560	COG0681	Belongs to the peptidase S26 family
AM438_RS11565	COG0571	ribonuclease III activity
AM438_RS11570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM438_RS11575	COG1381	Involved in DNA repair and RecF pathway recombination
AM438_RS11580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM438_RS11585	COG0736	holo-[acyl-carrier-protein] synthase activity
AM438_RS11590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM438_RS11670	COG1802	Transcriptional regulator
AM438_RS11670	COG4626	Terminase
AM438_RS11675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM438_RS11680	COG0305	Participates in initiation and elongation during chromosome replication
AM438_RS11735	COG3772	lysozyme
AM438_RS11765	COG2369	cell adhesion
AM438_RS11890	COG3539	Fimbrial protein
AM438_RS11895	COG3539	Fimbrial protein
AM438_RS11900	COG3121	Chaperone
AM438_RS11905	COG3188	usher protein
AM438_RS11910	COG3539	Fimbrial protein
AM438_RS11915	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM438_RS11920	COG0047	phosphoribosylformylglycinamidine synthase activity
AM438_RS11920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM438_RS11925	COG2205	protein histidine kinase activity
AM438_RS11930	COG3170	Tfp pilus assembly protein FimV
AM438_RS11935	COG2204	response regulator
AM438_RS11940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM438_RS11940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM438_RS11945	COG0347	Belongs to the P(II) protein family
AM438_RS11955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM438_RS11955	COG1017	nitric oxide dioxygenase activity
AM438_RS11960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM438_RS11965	COG2814	Major facilitator Superfamily
AM438_RS11980	COG0483	inositol monophosphate 1-phosphatase activity
AM438_RS11985	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM438_RS11990	COG1959	2 iron, 2 sulfur cluster binding
AM438_RS11995	COG1104	cysteine desulfurase activity
AM438_RS12000	COG0822	iron-sulfur transferase activity
AM438_RS12005	COG0316	Belongs to the HesB IscA family
AM438_RS12010	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM438_RS12015	COG0443	Heat shock 70 kDa protein
AM438_RS12020	COG0633	Ferredoxin
AM438_RS12025	COG2975	iron-sulfur cluster assembly
AM438_RS12030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM438_RS12040	COG2373	Large extracellular alpha-helical protein
AM438_RS12045	COG4953	penicillin-binding protein 1C
AM438_RS12050	COG0105	UTP biosynthetic process
AM438_RS12055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM438_RS12070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM438_RS12075	COG0124	histidyl-tRNA synthetase
AM438_RS12080	COG2976	Protein conserved in bacteria
AM438_RS12085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM438_RS12090	COG1160	GTP binding
AM438_RS12100	COG0408	coproporphyrinogen oxidase activity
AM438_RS12105	COG0456	acetyltransferase
AM438_RS12115	COG2837	iron assimilation
AM438_RS12125	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM438_RS12130	COG4208	sulfate ABC transporter
AM438_RS12135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM438_RS12140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM438_RS12145	COG2190	(PTS) system
AM438_RS12155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM438_RS12160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM438_RS12170	COG3115	cell septum assembly
AM438_RS12180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM438_RS12185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM438_RS12190	COG3530	Putative quorum-sensing-regulated virulence factor
AM438_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
AM438_RS12215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM438_RS12255	COG1396	sequence-specific DNA binding
AM438_RS12295	COG2067	long-chain fatty acid transport protein
AM438_RS12300	COG3691	Protein conserved in bacteria
AM438_RS12305	COG0183	Belongs to the thiolase family
AM438_RS12310	COG1024	Enoyl-CoA hydratase
AM438_RS12310	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM438_RS12315	COG2062	phosphohistidine phosphatase, SixA
AM438_RS12320	COG2840	Smr protein MutS2
AM438_RS12325	COG0783	Belongs to the Dps family
AM438_RS12335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM438_RS12340	COG0730	response to heat
AM438_RS12345	COG3101	peptidyl-lysine hydroxylation
AM438_RS12365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM438_RS12365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM438_RS12370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM438_RS12375	COG0697	spore germination
AM438_RS12380	COG2207	Transcriptional regulator
AM438_RS12385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM438_RS12390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM438_RS12400	COG0586	Pfam SNARE associated Golgi protein
AM438_RS12405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM438_RS12410	COG0285	dihydrofolate synthase activity
AM438_RS12415	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM438_RS12420	COG1286	toxin biosynthetic process
AM438_RS12425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM438_RS12430	COG0163	prenyltransferase activity
AM438_RS12435	COG1090	epimerase
AM438_RS12440	COG0625	glutathione transferase activity
AM438_RS12445	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM438_RS12455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM438_RS12465	COG3037	sugar-specific permease SgaT UlaA
AM438_RS12470	COG1203	CRISPR-associated helicase, Cas3
AM438_RS12500	COG1518	maintenance of DNA repeat elements
AM438_RS12505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM438_RS12530	COG0280	phosphate acetyltransferase
AM438_RS12530	COG0857	belongs to the CobB CobQ family
AM438_RS12535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM438_RS12540	COG3092	negative regulation of chromosome organization
AM438_RS12545	COG3013	Belongs to the UPF0304 family
AM438_RS12550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM438_RS12555	COG0490	domain, Protein
AM438_RS12555	COG0471	metal ion transport
AM438_RS12560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM438_RS12565	COG0436	Aminotransferase
AM438_RS12570	COG0583	DNA-binding transcription factor activity
AM438_RS12580	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM438_RS12585	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM438_RS12590	COG0649	NAD binding
AM438_RS12590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM438_RS12600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM438_RS12610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM438_RS12615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM438_RS12620	COG0839	Belongs to the complex I subunit 6 family
AM438_RS12625	COG0713	ATP synthesis coupled electron transport
AM438_RS12630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM438_RS12635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM438_RS12640	COG1007	ATP synthesis coupled electron transport
AM438_RS12655	COG1169	isochorismate synthase
AM438_RS12660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM438_RS12665	COG0596	Alpha beta hydrolase
AM438_RS12670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM438_RS12675	COG1441	menaquinone biosynthetic process
AM438_RS12695	COG0814	amino acid
AM438_RS12705	COG0633	Ferredoxin
AM438_RS12710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM438_RS12715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM438_RS12720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM438_RS12730	COG0784	Response regulator, receiver
AM438_RS12730	COG2205	protein histidine kinase activity
AM438_RS12735	COG2197	response regulator
AM438_RS12740	COG2198	Histidine kinase
AM438_RS12740	COG0642	Histidine kinase
AM438_RS12880	COG3302	dmso reductase anchor subunit
AM438_RS12885	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS12895	COG0668	transmembrane transport
AM438_RS12905	COG3247	response to pH
AM438_RS12915	COG1396	sequence-specific DNA binding
AM438_RS12920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM438_RS12945	COG1902	pentaerythritol trinitrate reductase activity
AM438_RS12950	COG5295	Hep Hag repeat protein
AM438_RS12950	COG5295	Hep Hag repeat protein
AM438_RS12960	COG1607	acyl-coa hydrolase
AM438_RS12990	COG2814	Major facilitator Superfamily
AM438_RS12995	COG1560	Kdo2-lipid A biosynthetic process
AM438_RS13035	COG0418	dihydroorotase activity
AM438_RS13075	COG1285	pathogenesis
AM438_RS13095	COG1360	Flagellar Motor Protein
AM438_RS13100	COG0643	Histidine kinase
AM438_RS13100	COG2198	Histidine kinase
AM438_RS13105	COG0835	chemotaxis
AM438_RS13110	COG0840	transmembrane signaling receptor activity
AM438_RS13115	COG0840	transmembrane signaling receptor activity
AM438_RS13125	COG2201	protein-glutamate methylesterase activity
AM438_RS13130	COG0745	RESPONSE REGULATOR receiver
AM438_RS13140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM438_RS13150	COG3210	domain, Protein
AM438_RS13170	COG1815	bacterial-type flagellum-dependent cell motility
AM438_RS13175	COG1558	bacterial-type flagellum-dependent cell motility
AM438_RS13200	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AM438_RS13205	COG1706	bacterial-type flagellum-dependent cell motility
AM438_RS13215	COG1256	bacterial-type flagellum assembly
AM438_RS13230	COG1987	bacterial-type flagellum assembly
AM438_RS13235	COG1338	Plays a role in the flagellum-specific transport system
AM438_RS13255	COG1580	Controls the rotational direction of flagella during chemotaxis
AM438_RS13265	COG2882	bacterial-type flagellum organization
AM438_RS13270	COG1157	protein secretion by the type III secretion system
AM438_RS13285	COG1766	The M ring may be actively involved in energy transduction
AM438_RS13290	COG1677	Flagellar hook-basal body complex protein FliE
AM438_RS13345	COG1191	sigma factor activity
AM438_RS13355	COG0506	proline dehydrogenase activity
AM438_RS13355	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM438_RS13355	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM438_RS13360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM438_RS13370	COG1113	amino acid transport
AM438_RS13385	COG0589	response to stress
AM438_RS13395	COG2226	methyltransferase
AM438_RS13400	COG1971	Probably functions as a manganese efflux pump
AM438_RS13405	COG1760	l-serine dehydratase
AM438_RS13410	COG0494	nUDIX hydrolase
AM438_RS13420	COG3140	Belongs to the UPF0181 family
AM438_RS13435	COG1115	amino acid carrier protein
AM438_RS13440	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM438_RS13445	COG1114	Component of the transport system for branched-chain amino acids
AM438_RS13450	COG0561	phosphatase activity
AM438_RS13465	COG1113	amino acid transport
AM438_RS13485	COG1830	Aldolase
AM438_RS13490	COG1597	lipid kinase activity
AM438_RS13495	COG0826	peptidase U32
AM438_RS13500	COG0745	RESPONSE REGULATOR receiver
AM438_RS13505	COG2205	protein histidine kinase activity
AM438_RS13510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM438_RS13515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM438_RS13520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM438_RS13525	COG3104	oligopeptide transport
AM438_RS13540	COG2239	Acts as a magnesium transporter
AM438_RS13550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM438_RS13555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM438_RS13560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM438_RS13565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM438_RS13570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM438_RS13575	COG2233	PERMEase
AM438_RS13580	COG0668	transmembrane transport
AM438_RS13585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM438_RS13590	COG2211	Major facilitator Superfamily
AM438_RS13595	COG1393	Belongs to the ArsC family
AM438_RS13600	COG4783	chaperone-mediated protein folding
AM438_RS13605	COG0628	permease
AM438_RS13610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM438_RS13615	COG2716	regulation of RNA biosynthetic process
AM438_RS13620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM438_RS13625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM438_RS13630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM438_RS13635	COG2321	neutral zinc metallopeptidase
AM438_RS13640	COG2707	UPF0756 membrane protein
AM438_RS13645	COG1444	tRNA N-acetyltransferase activity
AM438_RS13655	COG2832	Protein of unknown function (DUF454)
AM438_RS13665	COG1876	peptidase activity
AM438_RS13670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM438_RS13675	COG1393	Belongs to the ArsC family
AM438_RS13685	COG2197	response regulator
AM438_RS13690	COG0280	phosphate acetyltransferase
AM438_RS13690	COG0281	malic enzyme
AM438_RS13705	COG1770	oligopeptidase
AM438_RS13710	COG1629	transport
AM438_RS13710	COG4206	TonB-dependent receptor
AM438_RS13715	COG1570	exodeoxyribonuclease VII activity
AM438_RS13720	COG0516	GMP reductase activity
AM438_RS13720	COG0517	IMP dehydrogenase activity
AM438_RS13725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM438_RS13725	COG0519	Catalyzes the synthesis of GMP from XMP
AM438_RS13730	COG0582	viral genome integration into host DNA
AM438_RS13815	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM438_RS13855	COG3541	Predicted nucleotidyltransferase
AM438_RS13870	COG1324	tolerance protein
AM438_RS13875	COG2390	Transcriptional regulator
AM438_RS13880	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM438_RS13885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM438_RS13890	COG3842	ATPase activity
AM438_RS13935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM438_RS13950	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM438_RS13955	COG1494	fructose-1,6-bisphosphatase
AM438_RS13960	COG0778	Nitroreductase
AM438_RS13965	COG2197	response regulator
AM438_RS13970	COG0322	excinuclease ABC activity
AM438_RS13975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM438_RS14005	COG3683	transport system, periplasmic component
AM438_RS14010	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM438_RS14030	COG2076	Multidrug Resistance protein
AM438_RS14040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM438_RS14045	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM438_RS14050	COG2186	Transcriptional regulator
AM438_RS14055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM438_RS14060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM438_RS14065	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM438_RS14070	COG3713	MltA-interacting MipA family protein
AM438_RS14085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM438_RS14090	COG3139	Protein of unknown function (DUF1315)
AM438_RS14105	COG1335	isochorismatase
AM438_RS14110	COG0252	asparaginase activity
AM438_RS14115	COG0616	signal peptide processing
AM438_RS14120	COG0778	Nitroreductase
AM438_RS14125	COG0709	Synthesizes selenophosphate from selenide and ATP
AM438_RS14130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM438_RS14135	COG0708	Exodeoxyribonuclease III
AM438_RS14140	COG0583	DNA-binding transcription factor activity
AM438_RS14150	COG0788	formyltetrahydrofolate deformylase activity
AM438_RS14155	COG3012	SEC-C Motif Domain Protein
AM438_RS14160	COG0745	RESPONSE REGULATOR receiver
AM438_RS14165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM438_RS14180	COG1435	thymidine kinase activity
AM438_RS14185	COG1454	alcohol dehydrogenase
AM438_RS14185	COG1012	belongs to the aldehyde dehydrogenase family
AM438_RS14190	COG2095	MarC family integral membrane protein
AM438_RS14195	COG4608	Belongs to the ABC transporter superfamily
AM438_RS14205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM438_RS14210	COG0601	transmembrane transport
AM438_RS14215	COG4166	transmembrane transport
AM438_RS14220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM438_RS14235	COG0675	Transposase, IS605 OrfB family
AM438_RS14260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM438_RS14265	COG0444	Belongs to the ABC transporter superfamily
AM438_RS14275	COG1396	sequence-specific DNA binding
AM438_RS14285	COG3539	Fimbrial protein
AM438_RS14295	COG3188	usher protein
AM438_RS14310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM438_RS14315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM438_RS14320	COG1309	transcriptional regulator
AM438_RS14325	COG1012	belongs to the aldehyde dehydrogenase family
AM438_RS14330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM438_RS14335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM438_RS14340	COG0402	S-adenosylhomocysteine deaminase activity
AM438_RS14350	COG0113	porphobilinogen synthase activity
AM438_RS14370	COG0589	response to stress
AM438_RS14380	COG0589	response to stress
AM438_RS14405	COG2966	Psort location CytoplasmicMembrane, score
AM438_RS14410	COG3610	response to peptide
AM438_RS14420	COG2356	endonuclease I
AM438_RS14430	COG1702	phosphate starvation-inducible protein PhoH
AM438_RS14435	COG3152	Membrane
AM438_RS14450	COG1294	oxidase, subunit
AM438_RS14455	COG1271	oxidase subunit
AM438_RS14460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM438_RS14465	COG1280	lysine exporter protein (LysE YggA)
AM438_RS14475	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM438_RS14480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM438_RS14485	COG4558	Periplasmic binding protein
AM438_RS14490	COG3720	iron ion transport
AM438_RS14495	COG4771	TonB-dependent receptor
AM438_RS14500	COG4771	TonB-dependent receptor
AM438_RS14510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM438_RS14515	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM438_RS14520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM438_RS14520	COG0574	Belongs to the PEP-utilizing enzyme family
AM438_RS14525	COG0628	permease
AM438_RS14530	COG0277	FAD linked oxidase domain protein
AM438_RS14530	COG0247	lactate metabolic process
AM438_RS14535	COG2050	protein possibly involved in aromatic compounds catabolism
AM438_RS14545	COG0316	Belongs to the HesB IscA family
AM438_RS14550	COG0719	Fe-S assembly protein
AM438_RS14555	COG0396	ATPase activity
AM438_RS14560	COG0719	Fe-S assembly protein
AM438_RS14565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM438_RS14570	COG2166	iron-sulfur cluster assembly
AM438_RS14575	COG1376	ErfK ybiS ycfS ynhG family protein
AM438_RS14575	COG1388	LysM domain
AM438_RS14590	COG0076	glutamate decarboxylase activity
AM438_RS14595	COG0531	amino acid
AM438_RS14615	COG0534	Mate efflux family protein
AM438_RS14620	COG0307	riboflavin synthase, alpha
AM438_RS14625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM438_RS14630	COG2814	Major facilitator Superfamily
AM438_RS14635	COG0583	DNA-binding transcription factor activity
AM438_RS14640	COG1609	Transcriptional regulator
AM438_RS14650	COG0730	response to heat
AM438_RS14665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM438_RS14670	COG0582	viral genome integration into host DNA
AM438_RS14710	COG3723	Recombinational DNA repair protein, rece pathway
AM438_RS14770	COG0305	Participates in initiation and elongation during chromosome replication
AM438_RS14795	COG3477	response to acidic pH
AM438_RS14810	COG3772	lysozyme
AM438_RS14915	COG1192	Involved in chromosome partitioning
AM438_RS15020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM438_RS15030	COG0675	Transposase, IS605 OrfB family
AM438_RS15035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM438_RS15040	COG0346	lactoylglutathione lyase activity
AM438_RS15045	COG3313	Fe-S protein
AM438_RS15060	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM438_RS15065	COG0259	pyridoxamine-phosphate oxidase activity
AM438_RS15070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM438_RS15085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM438_RS15095	COG4172	Belongs to the ABC transporter superfamily
AM438_RS15100	COG4171	peptide transport system, permease
AM438_RS15110	COG4166	transmembrane transport
AM438_RS15115	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM438_RS15120	COG1842	Phage shock protein A
AM438_RS15130	COG1983	PspC domain protein
AM438_RS15140	COG3106	COG3106 Predicted ATPase
AM438_RS15145	COG3768	UPF0283 membrane protein
AM438_RS15160	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM438_RS15165	COG4166	transmembrane transport
AM438_RS15180	COG0598	Magnesium transport protein CorA
AM438_RS15200	COG0346	lactoylglutathione lyase activity
AM438_RS15215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM438_RS15235	COG2917	probably involved in intracellular septation
AM438_RS15250	COG3047	cAMP biosynthetic process
AM438_RS15260	COG0159	tryptophan synthase activity
AM438_RS15265	COG0133	tryptophan synthase activity
AM438_RS15275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM438_RS15280	COG0512	Glutamine amidotransferase of anthranilate synthase
AM438_RS15285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM438_RS15295	COG0009	L-threonylcarbamoyladenylate synthase
AM438_RS15300	COG1187	pseudouridine synthase activity
AM438_RS15315	COG1028	Short-chain dehydrogenase reductase Sdr
AM438_RS15320	COG0616	signal peptide processing
AM438_RS15330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM438_RS15350	COG0583	DNA-binding transcription factor activity
AM438_RS15360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM438_RS15370	COG1464	Belongs to the NlpA lipoprotein family
AM438_RS15375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM438_RS15380	COG0671	phosphoesterase, PA-phosphatase related
AM438_RS15385	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM438_RS15390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM438_RS15395	COG0284	orotidine-5'-phosphate decarboxylase activity
AM438_RS15400	COG0023	Translation Initiation Factor
AM438_RS15405	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AM438_RS15410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM438_RS15420	COG4659	FMN binding
AM438_RS15430	COG4656	Part of a membrane complex involved in electron transport
AM438_RS15440	COG4657	Part of a membrane complex involved in electron transport
AM438_RS15450	COG0673	inositol 2-dehydrogenase activity
AM438_RS15455	COG0385	Bile acid
AM438_RS15460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM438_RS15470	COG5339	Protein conserved in bacteria
AM438_RS15475	COG0114	fumarate hydratase activity
AM438_RS15490	COG0583	DNA-binding transcription factor activity
AM438_RS15495	COG1940	carbohydrate kinase activity
AM438_RS15500	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM438_RS15515	COG4221	oxidoreductase activity
AM438_RS15700	COG1902	pentaerythritol trinitrate reductase activity
AM438_RS15725	COG4628	conserved protein (DUF2132)
AM438_RS15730	COG1609	Transcriptional regulator
AM438_RS15730	COG2207	Transcriptional regulator
AM438_RS15735	COG0436	Aminotransferase
AM438_RS15740	COG1757	Na H antiporter
AM438_RS15745	COG2115	Belongs to the xylose isomerase family
AM438_RS15750	COG1070	Carbohydrate kinase
AM438_RS15770	COG0443	Heat shock 70 kDa protein
AM438_RS15780	COG1538	Outer membrane efflux protein
AM438_RS15785	COG1289	transmembrane transporter activity
AM438_RS15800	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM438_RS15810	COG0402	S-adenosylhomocysteine deaminase activity
AM438_RS15815	COG1671	Belongs to the UPF0178 family
AM438_RS15820	COG0488	(ABC) transporter
AM438_RS15830	COG1309	transcriptional regulator
AM438_RS15840	COG0583	DNA-binding transcription factor activity
AM438_RS15850	COG2814	Major facilitator Superfamily
AM438_RS15870	COG1464	Belongs to the NlpA lipoprotein family
AM438_RS15890	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM438_RS15895	COG0488	(ABC) transporter
AM438_RS15900	COG3097	Belongs to the UPF0267 family
AM438_RS15905	COG2169	Transcriptional regulator
AM438_RS15905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM438_RS15910	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM438_RS15930	COG0251	oxidation-reduction process
AM438_RS15940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM438_RS15950	COG2376	Dihydroxyacetone kinase
AM438_RS15970	COG1349	DNA-binding transcription factor activity
AM438_RS15975	COG0243	molybdopterin cofactor binding
AM438_RS15980	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS15985	COG3302	dmso reductase anchor subunit
AM438_RS15990	COG3381	protein complex oligomerization
AM438_RS15995	COG0590	tRNA wobble adenosine to inosine editing
AM438_RS16000	COG0666	response to abiotic stimulus
AM438_RS16005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM438_RS16010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM438_RS16015	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM438_RS16020	COG2205	protein histidine kinase activity
AM438_RS16025	COG0745	RESPONSE REGULATOR receiver
AM438_RS16030	COG0842	Transport permease protein
AM438_RS16035	COG1129	ABC transporter
AM438_RS16035	COG0842	Transport permease protein
AM438_RS16040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM438_RS16050	COG4974	Belongs to the 'phage' integrase family
AM438_RS16055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM438_RS16090	COG3634	alkyl hydroperoxide reductase activity
AM438_RS16105	COG1695	Transcriptional regulator
AM438_RS16115	COG0604	alcohol dehydrogenase
AM438_RS16115	COG1028	Short-chain dehydrogenase reductase Sdr
AM438_RS16115	COG3321	synthase
AM438_RS16130	COG0437	4 iron, 4 sulfur cluster binding
AM438_RS16135	COG0243	molybdopterin cofactor binding
AM438_RS16140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM438_RS16145	COG0589	response to stress
AM438_RS16150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM438_RS16155	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM438_RS16165	COG0531	amino acid
AM438_RS16180	COG3188	usher protein
AM438_RS16195	COG1643	Atp-dependent helicase
AM438_RS16210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM438_RS16235	COG3784	Protein of unknown function (DUF1318)
AM438_RS16245	COG2911	Protein conserved in bacteria
AM438_RS16250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM438_RS16265	COG2207	Transcriptional regulator
AM438_RS16265	COG3708	Transcriptional regulator
AM438_RS16275	COG4619	ABC transporter
AM438_RS16280	COG0390	transport system, permease component
AM438_RS16285	COG2983	Belongs to the UPF0260 family
AM438_RS16290	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM438_RS16295	COG2951	lytic endotransglycosylase activity
AM438_RS16300	COG3100	YcgL domain-containing protein
AM438_RS16305	COG0850	regulation of cytokinetic process
AM438_RS16310	COG2894	cell division
AM438_RS16315	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM438_RS16320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM438_RS16325	COG0318	PFAM AMP-dependent synthetase and ligase
AM438_RS16330	COG3065	identical protein binding
AM438_RS16340	COG1199	ATP-dependent helicase activity
AM438_RS16345	COG0251	oxidation-reduction process
AM438_RS16350	COG0702	epimerase
AM438_RS16355	COG2076	Multidrug Resistance protein
AM438_RS16360	COG2076	Multidrug Resistance protein
AM438_RS16365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM438_RS16370	COG1737	Transcriptional regulator
AM438_RS16375	COG0469	pyruvate kinase activity
AM438_RS16380	COG1560	Kdo2-lipid A biosynthetic process
AM438_RS16385	COG0739	heme binding
AM438_RS16390	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM438_RS16395	COG1121	(ABC) transporter
AM438_RS16400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM438_RS16405	COG2255	four-way junction helicase activity
AM438_RS16410	COG0632	four-way junction helicase activity
AM438_RS16415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM438_RS16420	COG0217	transcriptional regulatory protein
AM438_RS16425	COG0494	nUDIX hydrolase
AM438_RS16430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM438_RS16435	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM438_RS16440	COG2226	methyltransferase
AM438_RS16445	COG0500	methyltransferase
AM438_RS16450	COG0488	(ABC) transporter
AM438_RS16460	COG3142	Participates in the control of copper homeostasis
AM438_RS16465	COG3102	Protein conserved in bacteria
AM438_RS16470	COG0018	arginyl-trna synthetase
AM438_RS16480	COG0728	peptidoglycan biosynthetic process
AM438_RS16485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM438_RS16490	COG0477	Major facilitator Superfamily
AM438_RS16500	COG3381	protein complex oligomerization
AM438_RS16515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM438_RS16525	COG0659	secondary active sulfate transmembrane transporter activity
AM438_RS16535	COG1242	4 iron, 4 sulfur cluster binding
AM438_RS16540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM438_RS16545	COG2912	Transglutaminase-like superfamily
AM438_RS16555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM438_RS16560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM438_RS16565	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM438_RS16570	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM438_RS16575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM438_RS16585	COG0193	aminoacyl-tRNA hydrolase activity
AM438_RS16590	COG0012	GTP binding
AM438_RS16605	COG3209	COG3209 Rhs family protein
AM438_RS16625	COG3209	COG3209 Rhs family protein
AM438_RS16715	COG0586	Pfam SNARE associated Golgi protein
AM438_RS16730	COG2186	Transcriptional regulator
AM438_RS16735	COG0579	oxidoreductase
AM438_RS16740	COG2207	Transcriptional regulator
AM438_RS16745	COG0095	Lipoate-protein ligase
AM438_RS16750	COG0791	NLP P60 protein
AM438_RS16755	COG2076	Multidrug Resistance protein
AM438_RS16760	COG2076	Multidrug Resistance protein
AM438_RS16765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM438_RS16770	COG0726	polysaccharide deacetylase
AM438_RS16775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM438_RS16775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM438_RS16780	COG0463	Glycosyl transferase, family 2
AM438_RS16785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM438_RS16790	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AM438_RS16795	COG4139	cobalamin transport
AM438_RS16800	COG0776	regulation of translation
AM438_RS16805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM438_RS16805	COG0072	phenylalanine-tRNA ligase activity
AM438_RS16810	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM438_RS16815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM438_RS16820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM438_RS16825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM438_RS16830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM438_RS16845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM438_RS16865	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM438_RS16870	COG1121	(ABC) transporter
AM438_RS16875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM438_RS16880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM438_RS16885	COG3001	Fructosamine kinase
AM438_RS16895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM438_RS16900	COG1988	membrane-bound metal-dependent
AM438_RS16905	COG1823	symporter activity
AM438_RS16915	COG0501	Belongs to the peptidase M48B family
AM438_RS16935	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM438_RS16940	COG1956	GAF domain-containing protein
AM438_RS16945	COG2995	paraquat-inducible protein a
AM438_RS16950	COG3008	intermembrane lipid transfer
AM438_RS16965	COG1276	copper resistance
AM438_RS16970	COG2372	response to copper ion
AM438_RS16975	COG1528	Iron-storage protein
AM438_RS16995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AM438_RS17000	COG0675	Transposase, IS605 OrfB family
AM438_RS17010	COG1598	PFAM Uncharacterised protein family UPF0150
AM438_RS17015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AM438_RS17025	COG0024	Methionine aminopeptidase
AM438_RS17055	COG2841	Protein conserved in bacteria
AM438_RS17060	COG3272	Protein of unknown function (DUF1722)
AM438_RS17070	COG0500	methyltransferase
AM438_RS17075	COG3969	phosphoadenosine phosphosulfate
AM438_RS17080	COG1475	DNA binding
AM438_RS17100	COG0572	uridine kinase
AM438_RS17110	COG0702	epimerase
AM438_RS17115	COG1733	regulation of RNA biosynthetic process
AM438_RS17125	COG0071	Belongs to the small heat shock protein (HSP20) family
AM438_RS17130	COG1278	Cold shock
AM438_RS17150	COG0538	isocitrate dehydrogenase activity
AM438_RS17285	COG4626	Terminase
AM438_RS17285	COG1802	Transcriptional regulator
AM438_RS17310	COG3772	lysozyme
AM438_RS17330	COG4977	sequence-specific DNA binding
AM438_RS17330	COG1917	Cupin 2, conserved barrel domain protein
AM438_RS17335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM438_RS17340	COG3477	response to acidic pH
AM438_RS17345	COG1278	Cold shock
AM438_RS17355	COG1403	HNH endonuclease
AM438_RS17385	COG4197	protein conserved in bacteria, prophage-related
AM438_RS17405	COG5532	Uncharacterized conserved protein (DUF2303)
AM438_RS17410	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM438_RS17420	COG0582	viral genome integration into host DNA
AM438_RS17425	COG0538	isocitrate dehydrogenase activity
AM438_RS17430	COG1187	pseudouridine synthase activity
AM438_RS17440	COG0482	sulfurtransferase activity
AM438_RS17445	COG2915	High frequency lysogenization protein hflD homolog
AM438_RS17450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM438_RS17455	COG0745	RESPONSE REGULATOR receiver
AM438_RS17460	COG2205	protein histidine kinase activity
AM438_RS17465	COG2850	peptidyl-arginine hydroxylation
AM438_RS17485	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM438_RS17495	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM438_RS17500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM438_RS17505	COG3134	Outer membrane lipoprotein
AM438_RS17510	COG1252	NADH dehydrogenase
AM438_RS17520	COG1472	Belongs to the glycosyl hydrolase 3 family
AM438_RS17530	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM438_RS17535	COG5633	Lipoprotein
AM438_RS17540	COG0537	adenosine 5'-monophosphoramidase activity
AM438_RS17545	COG0084	hydrolase, TatD family'
AM438_RS17550	COG0470	DNA polymerase III
AM438_RS17555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM438_RS17560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM438_RS17565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM438_RS17570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM438_RS17575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM438_RS17590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM438_RS17595	COG0416	fatty acid biosynthetic process
AM438_RS17600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM438_RS17605	COG1399	metal-binding, possibly nucleic acid-binding protein
AM438_RS17610	COG0424	maF-like protein
AM438_RS17620	COG0564	pseudouridine synthase activity
AM438_RS17625	COG1530	ribonuclease E activity
AM438_RS17630	COG2926	Belongs to the UPF0265 family
AM438_RS17635	COG2211	Major facilitator Superfamily
AM438_RS17640	COG2925	Exonuclease
AM438_RS17655	COG0277	FAD linked oxidase domain protein
AM438_RS17660	COG0583	DNA-binding transcription factor activity
AM438_RS17665	COG3961	Belongs to the TPP enzyme family
AM438_RS17675	COG0531	amino acid
AM438_RS17685	COG4771	TonB-dependent receptor
AM438_RS17695	COG0833	amino acid
AM438_RS17700	COG0583	DNA-binding transcription factor activity
AM438_RS17705	COG2855	membrane
AM438_RS17710	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM438_RS17715	COG0494	nUDIX hydrolase
AM438_RS17725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM438_RS17740	COG0671	phosphoesterase, PA-phosphatase related
AM438_RS17745	COG0791	NLP P60 protein
AM438_RS17755	COG2814	Major facilitator Superfamily
AM438_RS17760	COG1187	pseudouridine synthase activity
AM438_RS17765	COG1061	Type III restriction enzyme res subunit
AM438_RS17770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM438_RS17775	COG3081	Nucleoid-associated protein
AM438_RS17780	COG3082	Protein of unknown function (DUF1414)
AM438_RS17850	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM438_RS17865	COG1560	Kdo2-lipid A biosynthetic process
AM438_RS17870	COG1278	Cold shock
AM438_RS17885	COG3708	Transcriptional regulator
AM438_RS17885	COG2207	Transcriptional regulator
AM438_RS17895	COG0656	L-ascorbic acid biosynthetic process
AM438_RS17900	COG0583	DNA-binding transcription factor activity
AM438_RS17915	COG3615	Tellurite resistance protein tehB
AM438_RS17925	COG0456	acetyltransferase
AM438_RS18075	COG0305	Participates in initiation and elongation during chromosome replication
AM438_RS18155	COG3723	Recombinational DNA repair protein, rece pathway
AM438_RS18205	COG0582	viral genome integration into host DNA
AM438_RS18215	COG2920	part of a sulfur-relay system
AM438_RS18220	COG1254	Belongs to the acylphosphatase family
AM438_RS18225	COG3785	DNA binding
AM438_RS18230	COG1832	CoA-binding protein
AM438_RS18235	COG1803	Methylglyoxal synthase
AM438_RS18240	COG0210	DNA helicase
AM438_RS18245	COG1289	transmembrane transporter activity
AM438_RS18250	COG3070	regulator of competence-specific genes
AM438_RS18260	COG2885	chlorophyll binding
AM438_RS18260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM438_RS18265	COG3120	sequence-specific DNA binding
AM438_RS18270	COG1067	ATP-dependent peptidase activity
AM438_RS18275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM438_RS18280	COG3130	regulation of translation
AM438_RS18290	COG3009	Protein conserved in bacteria
AM438_RS18295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM438_RS18295	COG3008	intermembrane lipid transfer
AM438_RS18300	COG2995	paraquat-inducible protein a
AM438_RS18305	COG0488	(ABC) transporter
AM438_RS18310	COG0116	Belongs to the methyltransferase superfamily
AM438_RS18310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM438_RS18315	COG0633	Ferredoxin
AM438_RS18315	COG3217	Mosc domain protein beta barrel domain protein
AM438_RS18325	COG0167	dihydroorotate dehydrogenase activity
AM438_RS18335	COG0308	aminopeptidase N
AM438_RS18340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM438_RS18350	COG0017	Asparaginyl-tRNA synthetase
AM438_RS18355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM438_RS18360	COG1448	Aminotransferase
AM438_RS18405	COG3501	Rhs element vgr protein
AM438_RS18495	COG3157	Type VI secretion system effector, Hcp
AM438_RS18500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM438_RS18505	COG3108	Peptidase M15
AM438_RS18510	COG2989	Protein conserved in bacteria
AM438_RS18515	COG3700	Belongs to the class B bacterial acid phosphatase family
AM438_RS18525	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM438_RS18530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM438_RS18535	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AM438_RS18540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM438_RS18545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM438_RS18550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM438_RS18555	COG2835	tetraacyldisaccharide 4'-kinase activity
AM438_RS18565	COG1663	tetraacyldisaccharide 4'-kinase activity
AM438_RS18570	COG1132	(ABC) transporter
AM438_RS18575	COG0658	competence protein
AM438_RS18575	COG2333	competence protein COMEC
AM438_RS18580	COG0776	regulation of translation
AM438_RS18585	COG0539	negative regulation of cytoplasmic translation
AM438_RS18590	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM438_RS18595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM438_RS18600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM438_RS18610	COG3210	domain, Protein
AM438_RS18615	COG0252	asparaginase activity
AM438_RS18620	COG1944	ATP diphosphatase activity
AM438_RS18625	COG2116	formate transmembrane transporter activity
AM438_RS18630	COG1882	Formate acetyltransferase
AM438_RS18635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM438_RS18645	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM438_RS18655	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM438_RS18660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM438_RS18665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM438_RS18670	COG3107	peptidoglycan biosynthetic process
AM438_RS18670	COG1674	ftsk spoiiie
AM438_RS18680	COG0492	ferredoxin-NADP+ reductase activity
AM438_RS18690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM438_RS18695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM438_RS18700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM438_RS18705	COG0542	response to heat
AM438_RS18710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM438_RS18715	COG1278	Cold shock
AM438_RS18720	COG1136	(ABC) transporter
AM438_RS18720	COG0577	efflux transmembrane transporter activity
AM438_RS18725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM438_RS18730	COG3593	DNA synthesis involved in DNA repair
AM438_RS18735	COG2431	L-lysine efflux transmembrane transporter activity
AM438_RS18740	COG0702	epimerase
AM438_RS18745	COG1126	abc transporter atp-binding protein
AM438_RS18750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM438_RS18755	COG4215	(ABC) transporter
AM438_RS18760	COG4160	amino acid transport
AM438_RS18765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM438_RS18780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM438_RS18785	COG0432	Pfam Uncharacterised protein family UPF0047
AM438_RS18790	COG0671	phosphoesterase, PA-phosphatase related
AM438_RS18795	COG0814	amino acid
AM438_RS18800	COG1760	l-serine dehydratase
AM438_RS18805	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AM438_RS18810	COG1686	Belongs to the peptidase S11 family
AM438_RS18815	COG0625	glutathione transferase activity
AM438_RS18820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM438_RS18825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM438_RS18830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM438_RS18840	COG0131	Imidazoleglycerol-phosphate dehydratase
AM438_RS18840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM438_RS18845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM438_RS18850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM438_RS18855	COG0107	imidazoleglycerol-phosphate synthase activity
AM438_RS18860	COG0140	phosphoribosyl-ATP diphosphatase activity
AM438_RS18860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM438_RS18865	COG1454	alcohol dehydrogenase
AM438_RS18870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM438_RS18995	COG4626	Terminase
AM438_RS18995	COG1802	Transcriptional regulator
AM438_RS19170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM438_RS19175	COG0675	Transposase, IS605 OrfB family
AM438_RS19180	COG1253	flavin adenine dinucleotide binding
AM438_RS19185	COG3069	C4-dicarboxylate transmembrane transporter activity
AM438_RS19190	COG2982	Protein involved in outer membrane biogenesis
AM438_RS19195	COG0717	Belongs to the dCTP deaminase family
AM438_RS19200	COG0572	uridine kinase
AM438_RS19205	COG0489	protein tyrosine kinase activity
AM438_RS19210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM438_RS19210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM438_RS19215	COG1380	Effector of murein hydrolase LrgA
AM438_RS19220	COG1346	cytolysis
AM438_RS19225	COG0295	cytidine deaminase activity
AM438_RS19230	COG0281	malic enzyme
AM438_RS19235	COG2949	membrane
AM438_RS19240	COG2311	Membrane
AM438_RS19245	COG0302	gtp cyclohydrolase
AM438_RS19250	COG0477	Major facilitator Superfamily
AM438_RS19260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM438_RS19295	COG0583	DNA-binding transcription factor activity
AM438_RS19300	COG2079	MmgE PrpD family protein
AM438_RS19315	COG3069	C4-dicarboxylate transmembrane transporter activity
AM438_RS19325	COG2897	thiosulfate sulfurtransferase activity
AM438_RS19340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM438_RS19345	COG0513	Belongs to the DEAD box helicase family
AM438_RS19350	COG1309	transcriptional regulator
AM438_RS19360	COG1131	(ABC) transporter
AM438_RS19365	COG0842	Transport permease protein
AM438_RS19370	COG0842	Transport permease protein
AM438_RS19375	COG0670	Belongs to the BI1 family
AM438_RS19380	COG0314	molybdopterin synthase activity
AM438_RS19385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM438_RS19390	COG0315	cyclic pyranopterin monophosphate synthase activity
AM438_RS19395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM438_RS19400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM438_RS19410	COG0556	nucleotide-excision repair
AM438_RS19420	COG2226	methyltransferase
AM438_RS19425	COG0156	8-amino-7-oxononanoate synthase activity
AM438_RS19430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM438_RS19440	COG2706	6-phosphogluconolactonase activity
AM438_RS19445	COG0561	phosphatase activity
AM438_RS19450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM438_RS19455	COG4149	molybdate abc transporter
AM438_RS19460	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM438_RS19470	COG2005	Transcriptional regulator
AM438_RS19470	COG3585	molybdate ion transport
AM438_RS19495	COG2831	hemolysin activation secretion protein
AM438_RS19500	COG1119	ATPase activity
AM438_RS19505	COG0588	phosphoglycerate mutase activity
AM438_RS19510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM438_RS19535	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM438_RS19540	COG2885	chlorophyll binding
AM438_RS19545	COG0823	Involved in the tonB-independent uptake of proteins
AM438_RS19550	COG3064	Membrane
AM438_RS19555	COG0848	biopolymer transport protein
AM438_RS19560	COG0811	peptide transport
AM438_RS19565	COG0824	Thioesterase
AM438_RS19570	COG3790	cyd operon protein YbgE
AM438_RS19575	COG4890	Cyd operon protein YbgT
AM438_RS19580	COG1294	oxidase, subunit
AM438_RS19585	COG1271	oxidase subunit
AM438_RS19590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM438_RS19595	COG0045	succinate-CoA ligase (ADP-forming) activity
AM438_RS19600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM438_RS19605	COG0567	Dehydrogenase, E1 component
AM438_RS19615	COG1053	succinate dehydrogenase
AM438_RS19620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM438_RS19640	COG2814	Major facilitator Superfamily
AM438_RS19650	COG0714	Associated with various cellular activities
AM438_RS19655	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM438_RS19660	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM438_RS19670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM438_RS19685	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AM438_RS19690	COG4807	Protein conserved in bacteria
AM438_RS19700	COG3609	addiction module antidote protein, CC2985 family
AM438_RS19705	COG4807	Protein conserved in bacteria
AM438_RS19710	COG0033	Phosphoglucomutase
AM438_RS19715	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated