locus-tag	class	description
AM402_RS00005	COG0826	peptidase U32
AM402_RS00010	COG3539	Fimbrial protein
AM402_RS00015	COG3539	Fimbrial protein
AM402_RS00020	COG3539	Fimbrial protein
AM402_RS00025	COG3188	usher protein
AM402_RS00030	COG3121	Chaperone
AM402_RS00035	COG3539	Fimbrial protein
AM402_RS00050	COG1566	PFAM secretion protein HlyD family protein
AM402_RS00055	COG3275	phosphorelay sensor kinase activity
AM402_RS00080	COG2271	Major facilitator Superfamily
AM402_RS00085	COG0251	oxidation-reduction process
AM402_RS00095	COG2964	Protein conserved in bacteria
AM402_RS00100	COG0513	Belongs to the DEAD box helicase family
AM402_RS00110	COG1185	polyribonucleotide nucleotidyltransferase activity
AM402_RS00115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM402_RS00120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM402_RS00125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM402_RS00130	COG3064	Membrane
AM402_RS00130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM402_RS00135	COG0195	Participates in both transcription termination and antitermination
AM402_RS00140	COG0779	Required for maturation of 30S ribosomal subunits
AM402_RS00155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM402_RS00160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM402_RS00165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM402_RS00170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM402_RS00175	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM402_RS00180	COG1534	Rna-binding protein
AM402_RS00190	COG2027	D-alanyl-D-alanine carboxypeptidase
AM402_RS00195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM402_RS00200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM402_RS00205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM402_RS00210	COG0142	geranyltranstransferase activity
AM402_RS00225	COG3423	Transcriptional regulator
AM402_RS00230	COG0039	L-malate dehydrogenase activity
AM402_RS00235	COG1438	arginine binding
AM402_RS00240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM402_RS00245	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM402_RS00250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM402_RS00270	COG2105	PFAM AIG2 family protein
AM402_RS00275	COG2911	Protein conserved in bacteria
AM402_RS00280	COG0729	surface antigen
AM402_RS00285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM402_RS00290	COG1253	flavin adenine dinucleotide binding
AM402_RS00300	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM402_RS00310	COG0545	Peptidyl-prolyl cis-trans isomerase
AM402_RS00315	COG1012	belongs to the aldehyde dehydrogenase family
AM402_RS00320	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM402_RS00325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM402_RS00330	COG0254	rRNA binding
AM402_RS00335	COG3061	Opacity-associated protein A
AM402_RS00340	COG0359	binds to the 23S rRNA
AM402_RS00345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM402_RS00350	COG2965	DNA replication, synthesis of RNA primer
AM402_RS00355	COG0360	Binds together with S18 to 16S ribosomal RNA
AM402_RS00360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM402_RS00365	COG0557	exoribonuclease II activity
AM402_RS00370	COG1959	2 iron, 2 sulfur cluster binding
AM402_RS00375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM402_RS00380	COG0330	HflC and HflK could
AM402_RS00385	COG0330	HflC and HflK could
AM402_RS00390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM402_RS00395	COG1923	regulation of RNA biosynthetic process
AM402_RS00400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM402_RS00405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM402_RS00410	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM402_RS00415	COG0802	atpase or kinase
AM402_RS00420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM402_RS00450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM402_RS00455	COG1162	GTPase activity
AM402_RS00460	COG0688	phosphatidylethanolamine metabolic process
AM402_RS00465	COG1511	domain protein
AM402_RS00465	COG3264	Mechanosensitive ion channel
AM402_RS00475	COG3539	Fimbrial protein
AM402_RS00480	COG3121	Chaperone
AM402_RS00485	COG3188	usher protein
AM402_RS00500	COG0675	Transposase, IS605 OrfB family
AM402_RS00505	COG0561	phosphatase activity
AM402_RS00510	COG2267	carboxylic ester hydrolase activity
AM402_RS00525	COG2050	protein possibly involved in aromatic compounds catabolism
AM402_RS00530	COG2962	Rard protein
AM402_RS00540	COG0210	DNA helicase
AM402_RS00545	COG1011	Hydrolase
AM402_RS00560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM402_RS00565	COG5567	small periplasmic lipoprotein
AM402_RS00570	COG1965	Belongs to the frataxin family
AM402_RS00580	COG0181	hydroxymethylbilane synthase activity
AM402_RS00590	COG2959	enzyme of heme biosynthesis
AM402_RS00595	COG3071	HemY protein
AM402_RS00625	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM402_RS00635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM402_RS00640	COG2244	polysaccharide biosynthetic process
AM402_RS00645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM402_RS00650	COG0456	acetyltransferase
AM402_RS00655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM402_RS00660	COG1088	dTDP-glucose 4,6-dehydratase activity
AM402_RS00665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM402_RS00670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM402_RS00680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM402_RS00685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM402_RS00690	COG3118	belongs to the thioredoxin family
AM402_RS00695	COG0513	Belongs to the DEAD box helicase family
AM402_RS00700	COG0248	Ppx GppA phosphatase
AM402_RS00705	COG0210	DNA helicase
AM402_RS00715	COG3041	Addiction module toxin RelE StbE family
AM402_RS00720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM402_RS00735	COG0129	dihydroxy-acid dehydratase activity
AM402_RS00745	COG3978	acetolactate synthase activity
AM402_RS00760	COG0606	chelatase, subunit chli
AM402_RS00765	COG3085	chromosome segregation
AM402_RS00770	COG0583	DNA-binding transcription factor activity
AM402_RS00810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM402_RS00820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM402_RS00825	COG0009	L-threonylcarbamoyladenylate synthase
AM402_RS00830	COG0551	DNA topoisomerase type I activity
AM402_RS00835	COG0758	DNA mediated transformation
AM402_RS00840	COG0242	peptide deformylase activity
AM402_RS00845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM402_RS00850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM402_RS00850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM402_RS00855	COG0569	domain protein
AM402_RS00860	COG1970	mechanosensitive ion channel activity
AM402_RS00865	COG3036	rescue of stalled ribosome
AM402_RS00870	COG0789	Transcriptional regulator
AM402_RS00875	COG0203	ribosomal protein L17
AM402_RS00885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM402_RS00895	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM402_RS00900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM402_RS00905	COG0201	protein transport
AM402_RS00910	COG0200	Binds to the 23S rRNA
AM402_RS00915	COG1841	ribosomal large subunit assembly
AM402_RS00920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM402_RS00925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM402_RS00930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM402_RS00935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM402_RS00940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM402_RS00945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM402_RS00950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM402_RS00955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM402_RS00960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM402_RS00965	COG0255	Belongs to the universal ribosomal protein uL29 family
AM402_RS00970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM402_RS00980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM402_RS00985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM402_RS00990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM402_RS00995	COG0089	rRNA binding
AM402_RS01000	COG0088	Forms part of the polypeptide exit tunnel
AM402_RS01005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM402_RS01010	COG0051	transcription antitermination factor activity, RNA binding
AM402_RS01055	COG1072	(Pantothenic acid kinase))
AM402_RS01065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM402_RS01100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM402_RS01105	COG4206	TonB-dependent receptor
AM402_RS01110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM402_RS01125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM402_RS01135	COG0165	Argininosuccinate lyase
AM402_RS01140	COG0137	argininosuccinate synthase activity
AM402_RS01145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM402_RS01150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM402_RS01155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM402_RS01160	COG0028	Belongs to the TPP enzyme family
AM402_RS01180	COG0583	DNA-binding transcription factor activity
AM402_RS01185	COG0477	Major facilitator Superfamily
AM402_RS01195	COG1216	Glycosyl transferase, family 2
AM402_RS01200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM402_RS01205	COG2862	Uncharacterized protein family, UPF0114
AM402_RS01210	COG0527	aspartate kinase activity
AM402_RS01210	COG0460	homoserine dehydrogenase
AM402_RS01215	COG0626	cystathionine gamma-synthase activity
AM402_RS01220	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AM402_RS01225	COG0254	rRNA binding
AM402_RS01230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM402_RS01235	COG1609	Transcriptional regulator
AM402_RS01240	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM402_RS01245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM402_RS01250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM402_RS01255	COG1575	Belongs to the MenA family. Type 1 subfamily
AM402_RS01260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM402_RS01265	COG3074	FtsZ-dependent cytokinesis
AM402_RS01275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM402_RS01280	COG2814	Major facilitator Superfamily
AM402_RS01285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM402_RS01290	COG3152	Membrane
AM402_RS01300	COG0149	triose-phosphate isomerase activity
AM402_RS01305	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM402_RS01310	COG0205	6-phosphofructokinase activity
AM402_RS01315	COG1028	Short-chain dehydrogenase reductase Sdr
AM402_RS01320	COG0438	transferase activity, transferring glycosyl groups
AM402_RS01470	COG4695	Portal protein
AM402_RS01545	COG3620	sequence-specific DNA binding
AM402_RS01550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM402_RS01555	COG3678	ATP-independent chaperone mediated protein folding
AM402_RS01560	COG0745	RESPONSE REGULATOR receiver
AM402_RS01565	COG2205	protein histidine kinase activity
AM402_RS01625	COG1215	transferase activity, transferring glycosyl groups
AM402_RS01630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM402_RS01640	COG1045	serine acetyltransferase
AM402_RS01645	COG1045	serine acetyltransferase
AM402_RS01655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AM402_RS01660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM402_RS01670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM402_RS01675	COG4942	peptidase
AM402_RS01680	COG2861	carbohydrate metabolic process
AM402_RS01690	COG1063	alcohol dehydrogenase
AM402_RS01695	COG0156	8-amino-7-oxononanoate synthase activity
AM402_RS01700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM402_RS01710	COG0859	PFAM glycosyl transferase family 9
AM402_RS01725	COG0859	PFAM glycosyl transferase family 9
AM402_RS01730	COG0438	transferase activity, transferring glycosyl groups
AM402_RS01740	COG1519	Transferase
AM402_RS01750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM402_RS01755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM402_RS01770	COG0438	transferase activity, transferring glycosyl groups
AM402_RS01780	COG0438	transferase activity, transferring glycosyl groups
AM402_RS01785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM402_RS01790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM402_RS01800	COG2003	Belongs to the UPF0758 family
AM402_RS01805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM402_RS01810	COG0756	dUTP diphosphatase activity
AM402_RS01815	COG1309	transcriptional regulator
AM402_RS01820	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM402_RS01825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM402_RS01830	COG1561	YicC-like family, N-terminal region
AM402_RS01850	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM402_RS01870	COG4106	trans-aconitate 2-methyltransferase activity
AM402_RS01875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM402_RS01880	COG0187	DNA topoisomerase II activity
AM402_RS01885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM402_RS01895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM402_RS01900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM402_RS01905	COG0594	ribonuclease P activity
AM402_RS01910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM402_RS01915	COG0706	membrane insertase activity
AM402_RS01920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM402_RS01930	COG3550	peptidyl-serine autophosphorylation
AM402_RS01970	COG0583	DNA-binding transcription factor activity
AM402_RS01975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM402_RS01990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM402_RS01995	COG0243	molybdopterin cofactor binding
AM402_RS01995	COG3383	formate dehydrogenase (NAD+) activity
AM402_RS02000	COG3383	formate dehydrogenase (NAD+) activity
AM402_RS02000	COG0243	molybdopterin cofactor binding
AM402_RS02005	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS02010	COG2864	formate dehydrogenase
AM402_RS02015	COG3058	Necessary for formate dehydrogenase activity
AM402_RS02020	COG1921	L-seryl-tRNASec selenium transferase activity
AM402_RS02025	COG3276	selenocysteine insertion sequence binding
AM402_RS02030	COG1368	sulfuric ester hydrolase activity
AM402_RS02035	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM402_RS02040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM402_RS02045	COG3706	GGDEF domain
AM402_RS02055	COG0457	Tetratricopeptide repeat
AM402_RS02065	COG1215	transferase activity, transferring glycosyl groups
AM402_RS02075	COG1940	carbohydrate kinase activity
AM402_RS02085	COG3111	PFAM Bacterial OB fold (BOF) protein
AM402_RS02110	COG3188	usher protein
AM402_RS02145	COG1288	antiporter activity
AM402_RS02155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM402_RS02170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM402_RS02175	COG1840	ABC-type Fe3 transport system, periplasmic component
AM402_RS02180	COG1178	ABC-type Fe3 transport system permease component
AM402_RS02185	COG3842	ATPase activity
AM402_RS02270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM402_RS02275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM402_RS02280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM402_RS02285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM402_RS02290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM402_RS02295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM402_RS02300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM402_RS02305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM402_RS02315	COG0356	it plays a direct role in the translocation of protons across the membrane
AM402_RS02320	COG3312	ion transport
AM402_RS02325	COG0357	Ribosomal RNA small subunit methyltransferase G
AM402_RS02330	COG0445	tRNA wobble uridine modification
AM402_RS02335	COG0716	FMN binding
AM402_RS02340	COG1522	sequence-specific DNA binding
AM402_RS02345	COG2502	aspartate--ammonia ligase
AM402_RS02350	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM402_RS02355	COG0714	Associated with various cellular activities
AM402_RS02360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM402_RS02365	COG0477	Major facilitator Superfamily
AM402_RS02370	COG2186	Transcriptional regulator
AM402_RS02395	COG0247	lactate metabolic process
AM402_RS02400	COG1139	Iron-sulfur cluster binding protein
AM402_RS02405	COG1139	Iron-sulfur cluster binding protein
AM402_RS02410	COG1556	Lactate utilization protein
AM402_RS02415	COG2194	sulfuric ester hydrolase activity
AM402_RS02420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM402_RS02425	COG3162	membrane
AM402_RS02430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM402_RS02435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM402_RS02440	COG2258	MOSC domain
AM402_RS02450	COG0675	Transposase, IS605 OrfB family
AM402_RS02455	COG0180	Tryptophanyl-tRNA synthetase
AM402_RS02460	COG0546	phosphoglycolate phosphatase activity
AM402_RS02465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM402_RS02480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM402_RS02485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM402_RS02490	COG4796	Type ii and iii secretion system protein
AM402_RS02510	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM402_RS02520	COG0494	nUDIX hydrolase
AM402_RS02530	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM402_RS02535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM402_RS02540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM402_RS02545	COG1741	Belongs to the pirin family
AM402_RS02555	COG2081	HI0933 family
AM402_RS02560	COG0306	phosphate transporter
AM402_RS02570	COG0589	response to stress
AM402_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
AM402_RS02585	COG0742	ribosomal rna small subunit methyltransferase
AM402_RS02625	COG3188	usher protein
AM402_RS02695	COG3501	Rhs element vgr protein
AM402_RS02710	COG3122	Protein conserved in bacteria
AM402_RS02720	COG1278	Cold shock
AM402_RS02725	COG1737	Transcriptional regulator
AM402_RS02730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS02730	COG1263	PTS System
AM402_RS02735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM402_RS02740	COG0733	neurotransmitter:sodium symporter activity
AM402_RS02745	COG3383	formate dehydrogenase (NAD+) activity
AM402_RS02750	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM402_RS02760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM402_RS02765	COG2731	YhcH YjgK YiaL family protein
AM402_RS02770	COG1737	Transcriptional regulator
AM402_RS02790	COG1285	pathogenesis
AM402_RS02795	COG2211	Major facilitator Superfamily
AM402_RS02805	COG1609	Transcriptional regulator
AM402_RS02810	COG3302	dmso reductase anchor subunit
AM402_RS02815	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS02840	COG4604	ABC transporter, ATP-binding protein
AM402_RS02845	COG4605	iron ion homeostasis
AM402_RS02850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM402_RS02855	COG4607	ABC-type enterochelin transport system periplasmic component
AM402_RS02860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM402_RS02865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM402_RS02870	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM402_RS02875	COG1917	Cupin 2, conserved barrel domain protein
AM402_RS02875	COG2169	Transcriptional regulator
AM402_RS02880	COG1486	melibiose metabolic process
AM402_RS02885	COG3394	polysaccharide catabolic process
AM402_RS02900	COG1073	alpha beta
AM402_RS02900	COG2226	methyltransferase
AM402_RS02905	COG0747	negative chemotaxis
AM402_RS02910	COG0601	transmembrane transport
AM402_RS02925	COG1124	(ABC) transporter
AM402_RS02935	COG1069	ribulokinase activity
AM402_RS02945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM402_RS02985	COG3189	MarR family transcriptional regulator
AM402_RS02990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM402_RS02995	COG1349	DNA-binding transcription factor activity
AM402_RS03000	COG0705	Rhomboid family
AM402_RS03005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM402_RS03010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM402_RS03010	COG0316	Belongs to the HesB IscA family
AM402_RS03015	COG1040	competence protein
AM402_RS03020	COG2267	carboxylic ester hydrolase activity
AM402_RS03035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM402_RS03040	COG1918	ferrous iron import across plasma membrane
AM402_RS03060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM402_RS03065	COG2252	PERMEase
AM402_RS03075	COG0736	holo-[acyl-carrier-protein] synthase activity
AM402_RS03085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM402_RS03090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM402_RS03095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM402_RS03100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM402_RS03115	COG1136	(ABC) transporter
AM402_RS03140	COG0765	amino acid transport
AM402_RS03145	COG0765	amino acid transport
AM402_RS03150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM402_RS03155	COG0704	Plays a role in the regulation of phosphate uptake
AM402_RS03165	COG0581	inorganic phosphate transmembrane transporter activity
AM402_RS03170	COG0573	inorganic phosphate transmembrane transporter activity
AM402_RS03175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM402_RS03190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM402_RS03195	COG2183	response to ionizing radiation
AM402_RS03235	COG1217	gtp-binding protein TYPA
AM402_RS03240	COG1011	Hydrolase
AM402_RS03245	COG1490	D-aminoacyl-tRNA deacylase activity
AM402_RS03250	COG0456	acetyltransferase
AM402_RS03255	COG1187	pseudouridine synthase activity
AM402_RS03265	COG2982	Protein involved in outer membrane biogenesis
AM402_RS03270	COG2233	PERMEase
AM402_RS03275	COG0786	glutamate:sodium symporter activity
AM402_RS03280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM402_RS03285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM402_RS03290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM402_RS03295	COG1758	RNA polymerase activity
AM402_RS03300	COG0194	GDP metabolic process
AM402_RS03305	COG2860	membrane
AM402_RS03310	COG0823	Involved in the tonB-independent uptake of proteins
AM402_RS03335	COG0751	glycine-tRNA ligase activity
AM402_RS03340	COG0752	glycyl-tRNA synthetase alpha subunit
AM402_RS03345	COG2818	Glycosylase
AM402_RS03350	COG3977	Valine--pyruvate aminotransferase
AM402_RS03355	COG2985	domain, Protein
AM402_RS03355	COG0569	domain protein
AM402_RS03360	COG5645	(Lipo)protein
AM402_RS03375	COG2831	hemolysin activation secretion protein
AM402_RS03380	COG0747	negative chemotaxis
AM402_RS03385	COG0601	transmembrane transport
AM402_RS03390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM402_RS03395	COG0444	Belongs to the ABC transporter superfamily
AM402_RS03400	COG4608	Belongs to the ABC transporter superfamily
AM402_RS03405	COG3210	domain, Protein
AM402_RS03410	COG2199	diguanylate cyclase activity
AM402_RS03410	COG2200	EAL domain
AM402_RS03420	COG1942	4-Oxalocrotonate Tautomerase
AM402_RS03425	COG1295	ribonuclease BN
AM402_RS03435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM402_RS03440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM402_RS03455	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM402_RS03460	COG0746	molybdenum cofactor guanylyltransferase activity
AM402_RS03465	COG3084	Protein conserved in bacteria
AM402_RS03470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM402_RS03475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM402_RS03485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM402_RS03485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM402_RS03490	COG0242	peptide deformylase activity
AM402_RS03500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM402_RS03510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM402_RS03515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM402_RS03520	COG1765	OsmC-like protein
AM402_RS03525	COG3954	Phosphoribulokinase
AM402_RS03530	COG3089	Belongs to the UPF0270 family
AM402_RS03535	COG0429	hydrolase of the alpha beta-hydrolase fold
AM402_RS03555	COG0840	transmembrane signaling receptor activity
AM402_RS03560	COG0840	transmembrane signaling receptor activity
AM402_RS03565	COG0840	transmembrane signaling receptor activity
AM402_RS03570	COG0488	(ABC) transporter
AM402_RS03575	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM402_RS03585	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM402_RS03590	COG1047	Peptidyl-prolyl cis-trans
AM402_RS03595	COG2900	Belongs to the SlyX family
AM402_RS03600	COG0545	Peptidyl-prolyl cis-trans isomerase
AM402_RS03610	COG2964	Protein conserved in bacteria
AM402_RS03615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM402_RS03620	COG2923	Belongs to the DsrF TusC family
AM402_RS03630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM402_RS03635	COG0049	tRNA binding
AM402_RS03640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM402_RS03655	COG0250	Participates in transcription elongation, termination and antitermination
AM402_RS03660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM402_RS03665	COG0081	regulation of translation
AM402_RS03670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM402_RS03675	COG0222	ribosome binding
AM402_RS03680	COG0085	RNA polymerase activity
AM402_RS03685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM402_RS03690	COG5464	transposase or invertase
AM402_RS03700	COG2022	thiamine diphosphate biosynthetic process
AM402_RS03705	COG2104	thiamine diphosphate biosynthetic process
AM402_RS03710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM402_RS03715	COG0352	thiamine-phosphate diphosphorylase activity
AM402_RS03720	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM402_RS03730	COG2816	NAD+ diphosphatase activity
AM402_RS03735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM402_RS03740	COG1515	deoxyribonuclease V activity
AM402_RS03745	COG3068	Protein conserved in bacteria
AM402_RS03760	COG0151	Belongs to the GarS family
AM402_RS03765	COG0138	bifunctional purine biosynthesis protein purh
AM402_RS03795	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM402_RS03805	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM402_RS03810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM402_RS03815	COG2224	Isocitrate lyase
AM402_RS03825	COG0800	Aldolase
AM402_RS03830	COG0129	dihydroxy-acid dehydratase activity
AM402_RS03855	COG0527	aspartate kinase activity
AM402_RS03860	COG0166	Belongs to the GPI family
AM402_RS03865	COG3161	chorismate lyase activity
AM402_RS03870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM402_RS03875	COG2937	Belongs to the GPAT DAPAT family
AM402_RS03880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM402_RS03885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM402_RS03890	COG0735	belongs to the Fur family
AM402_RS03900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM402_RS03905	COG0814	amino acid
AM402_RS03915	COG1448	Aminotransferase
AM402_RS03935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM402_RS03955	COG1177	transmembrane transport
AM402_RS03975	COG3539	Fimbrial protein
AM402_RS03980	COG3188	usher protein
AM402_RS04000	COG2873	o-acetylhomoserine
AM402_RS04035	COG1454	alcohol dehydrogenase
AM402_RS04035	COG1012	belongs to the aldehyde dehydrogenase family
AM402_RS04040	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM402_RS04050	COG1882	Formate acetyltransferase
AM402_RS04055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM402_RS04065	COG4869	propanediol catabolic process
AM402_RS04090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM402_RS04105	COG0789	Transcriptional regulator
AM402_RS04145	COG2207	Transcriptional regulator
AM402_RS04190	COG4790	Type iii secretion
AM402_RS04235	COG0157	Belongs to the NadC ModD family
AM402_RS04240	COG0500	methyltransferase
AM402_RS04245	COG1120	ATPase activity
AM402_RS04250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM402_RS04255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM402_RS04260	COG1609	Transcriptional regulator
AM402_RS04265	COG3265	gluconokinase activity
AM402_RS04270	COG2610	gluconate transmembrane transporter activity
AM402_RS04295	COG2992	FlgJ-related protein
AM402_RS04315	COG2137	regulation of response to DNA damage stimulus
AM402_RS04320	COG3397	chitin binding
AM402_RS04340	COG1024	Enoyl-CoA hydratase
AM402_RS04345	COG0318	PFAM AMP-dependent synthetase and ligase
AM402_RS04350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM402_RS04355	COG1960	acyl-CoA dehydrogenase activity
AM402_RS04375	COG0644	oxidoreductase
AM402_RS04380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM402_RS04385	COG2271	Major facilitator Superfamily
AM402_RS04390	COG0318	PFAM AMP-dependent synthetase and ligase
AM402_RS04400	COG1924	4 iron, 4 sulfur cluster binding
AM402_RS04415	COG2610	gluconate transmembrane transporter activity
AM402_RS04420	COG1960	acyl-CoA dehydrogenase activity
AM402_RS04425	COG2086	electron transfer activity
AM402_RS04430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM402_RS04435	COG0644	oxidoreductase
AM402_RS04440	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM402_RS04445	COG4977	sequence-specific DNA binding
AM402_RS04450	COG2255	four-way junction helicase activity
AM402_RS04465	COG1704	LemA family
AM402_RS04470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM402_RS04490	COG0305	Participates in initiation and elongation during chromosome replication
AM402_RS04540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM402_RS04570	COG1982	Orn Lys Arg decarboxylase major
AM402_RS04590	COG3059	membrane
AM402_RS04600	COG2801	Transposase and inactivated derivatives
AM402_RS04665	COG1132	(ABC) transporter
AM402_RS04665	COG2375	cellular response to nickel ion
AM402_RS04685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM402_RS04685	COG3433	isochorismatase activity
AM402_RS04685	COG2226	methyltransferase
AM402_RS04695	COG2814	Major facilitator Superfamily
AM402_RS04700	COG4771	TonB-dependent receptor
AM402_RS04930	COG1309	transcriptional regulator
AM402_RS04935	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM402_RS04950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM402_RS04955	COG0459	protein refolding
AM402_RS05005	COG3188	usher protein
AM402_RS05020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM402_RS05025	COG0698	ribose 5-phosphate isomerase
AM402_RS05030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM402_RS05035	COG0651	ATP synthesis coupled electron transport
AM402_RS05040	COG0650	Formate hydrogenlyase subunit 4
AM402_RS05045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM402_RS05050	COG4237	Hydrogenase 4 membrane
AM402_RS05055	COG0651	ATP synthesis coupled electron transport
AM402_RS05060	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM402_RS05060	COG3261	NADH dehydrogenase
AM402_RS05065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM402_RS05070	COG3260	NADH ubiquinone oxidoreductase 20
AM402_RS05080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM402_RS05085	COG1216	Glycosyl transferase, family 2
AM402_RS05100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM402_RS05120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM402_RS05125	COG1328	CTP reductase activity
AM402_RS05130	COG3726	membrane protein affecting hemolysin expression
AM402_RS05135	COG0560	Phosphoserine phosphatase
AM402_RS05155	COG2382	esterase
AM402_RS05165	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM402_RS05190	COG2813	Specifically methylates the guanine in position
AM402_RS05215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM402_RS05250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM402_RS05385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM402_RS05400	COG0681	Belongs to the peptidase S26 family
AM402_RS05420	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM402_RS05430	COG2207	Transcriptional regulator
AM402_RS05445	COG0629	single-stranded DNA binding
AM402_RS05460	COG0714	Associated with various cellular activities
AM402_RS05485	COG2003	Belongs to the UPF0758 family
AM402_RS05505	COG1401	restriction endodeoxyribonuclease activity
AM402_RS05570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM402_RS05580	COG4667	esterase of the alpha-beta hydrolase superfamily
AM402_RS05585	COG0084	hydrolase, TatD family'
AM402_RS05590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM402_RS05595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM402_RS05600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AM402_RS05605	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM402_RS05610	COG0813	purine-nucleoside phosphorylase activity
AM402_RS05615	COG2851	Citrate transporter
AM402_RS05625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM402_RS05630	COG0469	pyruvate kinase activity
AM402_RS05635	COG2271	Major facilitator Superfamily
AM402_RS05645	COG4191	Histidine kinase
AM402_RS05655	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM402_RS05655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM402_RS05655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM402_RS05660	COG1461	Dihydroxyacetone kinase
AM402_RS05665	COG2376	Dihydroxyacetone kinase
AM402_RS05720	COG1358	cellular component organization or biogenesis
AM402_RS05770	COG0840	transmembrane signaling receptor activity
AM402_RS05780	COG0583	DNA-binding transcription factor activity
AM402_RS05785	COG0243	molybdopterin cofactor binding
AM402_RS05790	COG1271	oxidase subunit
AM402_RS05795	COG1294	oxidase, subunit
AM402_RS05805	COG3781	membrane
AM402_RS05825	COG0358	DNA primase activity
AM402_RS05830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM402_RS05840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM402_RS05845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AM402_RS05865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM402_RS05870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM402_RS05875	COG0617	tRNA 3'-terminal CCA addition
AM402_RS05880	COG4991	sh3 domain protein
AM402_RS05885	COG3025	triphosphatase activity
AM402_RS05890	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM402_RS05895	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM402_RS05895	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM402_RS05915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM402_RS05920	COG3384	dioxygenase
AM402_RS05925	COG0754	glutathionylspermidine amidase activity
AM402_RS05930	COG5463	Belongs to the UPF0441 family
AM402_RS05935	COG1538	Outer membrane efflux protein
AM402_RS05940	COG0494	nUDIX hydrolase
AM402_RS05945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM402_RS05950	COG3150	esterase
AM402_RS05955	COG0187	DNA topoisomerase II activity
AM402_RS05960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM402_RS05965	COG0204	Acyl-transferase
AM402_RS05970	COG2132	Multicopper oxidase
AM402_RS05990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM402_RS05995	COG2967	ApaG domain
AM402_RS06000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM402_RS06005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM402_RS06010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM402_RS06015	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM402_RS06020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM402_RS06025	COG0564	pseudouridine synthase activity
AM402_RS06030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM402_RS06035	COG0417	DNA replication proofreading
AM402_RS06040	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AM402_RS06045	COG1178	ABC-type Fe3 transport system permease component
AM402_RS06050	COG4143	(ABC) transporter
AM402_RS06055	COG0494	nUDIX hydrolase
AM402_RS06065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM402_RS06070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM402_RS06100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM402_RS06105	COG1025	Belongs to the peptidase M16 family
AM402_RS06110	COG1074	ATP-dependent DNA helicase activity
AM402_RS06115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM402_RS06120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM402_RS06120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM402_RS06125	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM402_RS06145	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM402_RS06150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM402_RS06155	COG2166	iron-sulfur cluster assembly
AM402_RS06160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM402_RS06165	COG0583	DNA-binding transcription factor activity
AM402_RS06170	COG2363	Small membrane protein
AM402_RS06175	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AM402_RS06180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM402_RS06185	COG1611	Belongs to the LOG family
AM402_RS06190	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM402_RS06190	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM402_RS06200	COG3098	single-species biofilm formation
AM402_RS06210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS06210	COG1263	PTS System
AM402_RS06220	COG0716	FMN binding
AM402_RS06230	COG2171	N-acyltransferase activity
AM402_RS06235	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM402_RS06245	COG0052	Belongs to the universal ribosomal protein uS2 family
AM402_RS06250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM402_RS06255	COG0528	UMP kinase activity
AM402_RS06260	COG0233	cytoplasmic translational termination
AM402_RS06265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM402_RS06270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM402_RS06275	COG0575	Belongs to the CDS family
AM402_RS06295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM402_RS06300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM402_RS06305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM402_RS06310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM402_RS06315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM402_RS06325	COG0825	malonyl-CoA metabolic process
AM402_RS06335	COG0037	tRNA processing
AM402_RS06340	COG4568	rho-dependent transcription termination
AM402_RS06345	COG3015	lipoprotein NlpE involved in copper resistance
AM402_RS06350	COG0442	prolyl-tRNA aminoacylation
AM402_RS06355	COG1720	tRNA m6t6A37 methyltransferase activity
AM402_RS06365	COG1464	Belongs to the NlpA lipoprotein family
AM402_RS06370	COG2011	ABC-type metal ion transport system permease component
AM402_RS06375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM402_RS06380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM402_RS06435	COG0602	queuosine metabolic process
AM402_RS06440	COG0720	synthase
AM402_RS06445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM402_RS06450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM402_RS06455	COG0175	sulfate reduction
AM402_RS06460	COG1648	precorrin-2 dehydrogenase activity
AM402_RS06460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM402_RS06465	COG0175	sulfate reduction
AM402_RS06470	COG2895	sulfate adenylyltransferase (ATP) activity
AM402_RS06485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM402_RS06490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM402_RS06495	COG0585	pseudouridine synthase activity
AM402_RS06500	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM402_RS06505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM402_RS06510	COG4942	peptidase
AM402_RS06510	COG1388	LysM domain
AM402_RS06520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM402_RS06530	COG3711	transcriptional antiterminator
AM402_RS06535	COG2190	(PTS) system
AM402_RS06535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS06535	COG1263	PTS System
AM402_RS06540	COG0613	PHP domain protein
AM402_RS06610	COG3539	Fimbrial protein
AM402_RS06635	COG0471	metal ion transport
AM402_RS06650	COG1335	isochorismatase
AM402_RS06655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM402_RS06660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM402_RS06670	COG0549	Belongs to the carbamate kinase family
AM402_RS06680	COG0583	DNA-binding transcription factor activity
AM402_RS06690	COG4589	Belongs to the CDS family
AM402_RS06705	COG4566	intracellular signal transduction
AM402_RS06725	COG2962	Rard protein
AM402_RS06730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM402_RS06735	COG0326	Molecular chaperone. Has ATPase activity
AM402_RS06740	COG0563	adenylate kinase activity
AM402_RS06745	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM402_RS06750	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM402_RS06755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM402_RS06760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM402_RS06760	COG4651	solute:proton antiporter activity
AM402_RS06770	COG0675	Transposase, IS605 OrfB family
AM402_RS06775	COG0737	Belongs to the 5'-nucleotidase family
AM402_RS06785	COG3735	TraB family
AM402_RS06800	COG0789	Transcriptional regulator
AM402_RS06810	COG0330	HflC and HflK could
AM402_RS06815	COG3118	belongs to the thioredoxin family
AM402_RS06820	COG0300	oxidoreductase activity
AM402_RS06825	COG2755	lipolytic protein G-D-S-L family
AM402_RS06830	COG4181	ATPase activity
AM402_RS06835	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM402_RS06840	COG0668	transmembrane transport
AM402_RS06850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM402_RS06855	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM402_RS06860	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM402_RS06865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM402_RS06870	COG0215	cysteine-tRNA ligase activity
AM402_RS06875	COG1105	Belongs to the carbohydrate kinase PfkB family
AM402_RS06880	COG2501	S4 domain
AM402_RS06885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM402_RS06895	COG0582	viral genome integration into host DNA
AM402_RS07030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM402_RS07040	COG0640	Transcriptional regulator
AM402_RS07045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM402_RS07050	COG0384	phenazine biosynthesis protein PhzF
AM402_RS07070	COG0800	Aldolase
AM402_RS07075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM402_RS07090	COG3119	arylsulfatase activity
AM402_RS07095	COG0641	radical SAM
AM402_RS07100	COG1349	DNA-binding transcription factor activity
AM402_RS07110	COG2222	sugar isomerase
AM402_RS07115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS07120	COG3715	PTS system
AM402_RS07125	COG3716	PTS system mannose fructose sorbose family IID component
AM402_RS07130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS07130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM402_RS07135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM402_RS07145	COG1028	Short-chain dehydrogenase reductase Sdr
AM402_RS07185	COG3119	arylsulfatase activity
AM402_RS07195	COG5295	Hep Hag repeat protein
AM402_RS07210	COG3038	cytochrome b561
AM402_RS07215	COG2353	YceI-like domain
AM402_RS07220	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AM402_RS07225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM402_RS07240	COG1115	amino acid carrier protein
AM402_RS07250	COG1151	hydroxylamine reductase activity
AM402_RS07255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM402_RS07265	COG2239	Acts as a magnesium transporter
AM402_RS07270	COG3091	SprT-like family
AM402_RS07275	COG0640	Transcriptional regulator
AM402_RS07290	COG0457	Tetratricopeptide repeat
AM402_RS07290	COG3118	belongs to the thioredoxin family
AM402_RS07295	COG1215	transferase activity, transferring glycosyl groups
AM402_RS07305	COG1192	Involved in chromosome partitioning
AM402_RS07315	COG2194	sulfuric ester hydrolase activity
AM402_RS07320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM402_RS07325	COG1166	arginine decarboxylase activity
AM402_RS07330	COG0010	Belongs to the arginase family
AM402_RS07340	COG3657	addiction module killer protein
AM402_RS07350	COG3066	DNA modification
AM402_RS07355	COG4533	DNA binding
AM402_RS07360	COG0066	3-isopropylmalate dehydratase activity
AM402_RS07365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM402_RS07370	COG0473	3-isopropylmalate dehydrogenase activity
AM402_RS07375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM402_RS07390	COG1022	Amp-dependent synthetase and ligase
AM402_RS07400	COG2001	Belongs to the MraZ family
AM402_RS07405	COG0275	rRNA processing
AM402_RS07415	COG0768	penicillin binding
AM402_RS07420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM402_RS07425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM402_RS07430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM402_RS07440	COG0772	Belongs to the SEDS family
AM402_RS07445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM402_RS07450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM402_RS07460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM402_RS07465	COG0849	cell division
AM402_RS07475	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AM402_RS07490	COG0653	protein targeting
AM402_RS07495	COG0789	Transcriptional regulator
AM402_RS07520	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM402_RS07525	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AM402_RS07530	COG0237	dephospho-CoA kinase activity
AM402_RS07540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM402_RS07545	COG4969	Belongs to the N-Me-Phe pilin family
AM402_RS07550	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM402_RS07555	COG2186	Transcriptional regulator
AM402_RS07560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM402_RS07565	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM402_RS07570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM402_RS07575	COG3064	Membrane
AM402_RS07575	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM402_RS07575	COG1073	alpha beta
AM402_RS07590	COG3112	Uncharacterised protein family (UPF0231)
AM402_RS07600	COG1279	arginine transmembrane transporter activity
AM402_RS07620	COG0583	DNA-binding transcription factor activity
AM402_RS07625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM402_RS07630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM402_RS07640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM402_RS07650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM402_RS07660	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AM402_RS07665	COG3079	Belongs to the UPF0149 family
AM402_RS07670	COG0006	proline dipeptidase activity
AM402_RS07675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM402_RS07680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM402_RS07685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM402_RS07690	COG0509	glycine decarboxylation via glycine cleavage system
AM402_RS07695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM402_RS07695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM402_RS07705	COG0354	folic acid binding
AM402_RS07710	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM402_RS07725	COG0716	FMN binding
AM402_RS07735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM402_RS07740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM402_RS07750	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM402_RS07755	COG4974	Belongs to the 'phage' integrase family
AM402_RS07820	COG4695	Portal protein
AM402_RS07990	COG3539	Fimbrial protein
AM402_RS07995	COG3121	Chaperone
AM402_RS08000	COG3188	usher protein
AM402_RS08075	COG2841	Protein conserved in bacteria
AM402_RS08080	COG4574	serine-type endopeptidase inhibitor activity
AM402_RS08085	COG0589	response to stress
AM402_RS08090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM402_RS08100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM402_RS08105	COG1085	galactose-1-phosphate uridylyltransferase
AM402_RS08110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM402_RS08115	COG2017	converts alpha-aldose to the beta-anomer
AM402_RS08120	COG1609	Transcriptional regulator
AM402_RS08130	COG4771	TonB-dependent receptor
AM402_RS08135	COG2819	hydrolase of the alpha beta superfamily
AM402_RS08145	COG3738	Protein conserved in bacteria
AM402_RS08150	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM402_RS08165	COG1556	Lactate utilization protein
AM402_RS08170	COG1139	Iron-sulfur cluster binding protein
AM402_RS08175	COG0247	lactate metabolic process
AM402_RS08180	COG1620	l-lactate permease
AM402_RS08185	COG2814	Major facilitator Superfamily
AM402_RS08190	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM402_RS08205	COG0579	oxidoreductase
AM402_RS08270	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM402_RS08275	COG0732	type I restriction modification DNA specificity domain
AM402_RS08280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM402_RS08285	COG1674	ftsk spoiiie
AM402_RS08285	COG3107	peptidoglycan biosynthetic process
AM402_RS08295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM402_RS08325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM402_RS08330	COG2867	negative regulation of translational initiation
AM402_RS08335	COG2914	Belongs to the UPF0125 (RnfH) family
AM402_RS08345	COG0497	DNA recombination
AM402_RS08350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM402_RS08355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM402_RS08360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM402_RS08370	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AM402_RS08375	COG0513	Belongs to the DEAD box helicase family
AM402_RS08380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM402_RS08385	COG1595	DNA-templated transcription, initiation
AM402_RS08390	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM402_RS08395	COG3026	antisigma factor binding
AM402_RS08400	COG3086	response to oxidative stress
AM402_RS08405	COG0481	GTPase activity
AM402_RS08410	COG0681	Belongs to the peptidase S26 family
AM402_RS08415	COG0571	ribonuclease III activity
AM402_RS08420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM402_RS08425	COG1381	Involved in DNA repair and RecF pathway recombination
AM402_RS08430	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM402_RS08435	COG0736	holo-[acyl-carrier-protein] synthase activity
AM402_RS08440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM402_RS08450	COG3539	Fimbrial protein
AM402_RS08455	COG3539	Fimbrial protein
AM402_RS08460	COG3121	Chaperone
AM402_RS08465	COG3188	usher protein
AM402_RS08470	COG3539	Fimbrial protein
AM402_RS08480	COG3539	Fimbrial protein
AM402_RS08485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM402_RS08490	COG0047	phosphoribosylformylglycinamidine synthase activity
AM402_RS08490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM402_RS08495	COG2205	protein histidine kinase activity
AM402_RS08500	COG3170	Tfp pilus assembly protein FimV
AM402_RS08505	COG2204	response regulator
AM402_RS08510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM402_RS08510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM402_RS08515	COG0347	Belongs to the P(II) protein family
AM402_RS08525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM402_RS08525	COG1017	nitric oxide dioxygenase activity
AM402_RS08530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM402_RS08535	COG2814	Major facilitator Superfamily
AM402_RS08550	COG0483	inositol monophosphate 1-phosphatase activity
AM402_RS08555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM402_RS08560	COG1959	2 iron, 2 sulfur cluster binding
AM402_RS08565	COG1104	cysteine desulfurase activity
AM402_RS08570	COG0822	iron-sulfur transferase activity
AM402_RS08575	COG0316	Belongs to the HesB IscA family
AM402_RS08580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM402_RS08585	COG0443	Heat shock 70 kDa protein
AM402_RS08590	COG0633	Ferredoxin
AM402_RS08595	COG2975	iron-sulfur cluster assembly
AM402_RS08600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM402_RS08610	COG2373	Large extracellular alpha-helical protein
AM402_RS08615	COG4953	penicillin-binding protein 1C
AM402_RS08620	COG0105	UTP biosynthetic process
AM402_RS08625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM402_RS08640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM402_RS08645	COG0124	histidyl-tRNA synthetase
AM402_RS08650	COG2976	Protein conserved in bacteria
AM402_RS08655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM402_RS08660	COG1160	GTP binding
AM402_RS08670	COG0408	coproporphyrinogen oxidase activity
AM402_RS08675	COG0456	acetyltransferase
AM402_RS08685	COG2837	iron assimilation
AM402_RS08695	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM402_RS08700	COG4208	sulfate ABC transporter
AM402_RS08705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM402_RS08710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM402_RS08715	COG2190	(PTS) system
AM402_RS08725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM402_RS08730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM402_RS08740	COG3115	cell septum assembly
AM402_RS08750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM402_RS08755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM402_RS08760	COG3530	Putative quorum-sensing-regulated virulence factor
AM402_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
AM402_RS08785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM402_RS08825	COG1396	sequence-specific DNA binding
AM402_RS08870	COG2067	long-chain fatty acid transport protein
AM402_RS08875	COG3691	Protein conserved in bacteria
AM402_RS08880	COG0183	Belongs to the thiolase family
AM402_RS08885	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM402_RS08885	COG1024	Enoyl-CoA hydratase
AM402_RS08890	COG2062	phosphohistidine phosphatase, SixA
AM402_RS08895	COG2840	Smr protein MutS2
AM402_RS08900	COG0783	Belongs to the Dps family
AM402_RS08910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM402_RS08915	COG0730	response to heat
AM402_RS08920	COG3101	peptidyl-lysine hydroxylation
AM402_RS08940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM402_RS08940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM402_RS08945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM402_RS08950	COG0697	spore germination
AM402_RS08955	COG2207	Transcriptional regulator
AM402_RS08960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM402_RS08965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM402_RS08975	COG0586	Pfam SNARE associated Golgi protein
AM402_RS08980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM402_RS08985	COG0285	dihydrofolate synthase activity
AM402_RS08990	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM402_RS08995	COG1286	toxin biosynthetic process
AM402_RS09000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM402_RS09005	COG0163	prenyltransferase activity
AM402_RS09010	COG1090	epimerase
AM402_RS09015	COG0625	glutathione transferase activity
AM402_RS09020	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM402_RS09030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM402_RS09040	COG3037	sugar-specific permease SgaT UlaA
AM402_RS09065	COG0857	belongs to the CobB CobQ family
AM402_RS09065	COG0280	phosphate acetyltransferase
AM402_RS09070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM402_RS09075	COG3092	negative regulation of chromosome organization
AM402_RS09080	COG3013	Belongs to the UPF0304 family
AM402_RS09085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM402_RS09090	COG0471	metal ion transport
AM402_RS09090	COG0490	domain, Protein
AM402_RS09095	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM402_RS09100	COG0436	Aminotransferase
AM402_RS09105	COG0583	DNA-binding transcription factor activity
AM402_RS09115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM402_RS09120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM402_RS09125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM402_RS09125	COG0649	NAD binding
AM402_RS09135	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM402_RS09145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM402_RS09150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM402_RS09155	COG0839	Belongs to the complex I subunit 6 family
AM402_RS09160	COG0713	ATP synthesis coupled electron transport
AM402_RS09165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM402_RS09170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM402_RS09175	COG1007	ATP synthesis coupled electron transport
AM402_RS09195	COG1169	isochorismate synthase
AM402_RS09200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM402_RS09205	COG0596	Alpha beta hydrolase
AM402_RS09210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM402_RS09215	COG1441	menaquinone biosynthetic process
AM402_RS09235	COG0814	amino acid
AM402_RS09245	COG0633	Ferredoxin
AM402_RS09250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM402_RS09255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM402_RS09260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM402_RS09270	COG2205	protein histidine kinase activity
AM402_RS09270	COG0784	Response regulator, receiver
AM402_RS09275	COG2197	response regulator
AM402_RS09280	COG2198	Histidine kinase
AM402_RS09280	COG0642	Histidine kinase
AM402_RS09415	COG3302	dmso reductase anchor subunit
AM402_RS09420	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS09425	COG0243	molybdopterin cofactor binding
AM402_RS09430	COG0668	transmembrane transport
AM402_RS09435	COG3247	response to pH
AM402_RS09445	COG1396	sequence-specific DNA binding
AM402_RS09450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM402_RS09475	COG1902	pentaerythritol trinitrate reductase activity
AM402_RS09490	COG1607	acyl-coa hydrolase
AM402_RS09505	COG2814	Major facilitator Superfamily
AM402_RS09510	COG1560	Kdo2-lipid A biosynthetic process
AM402_RS09550	COG0418	dihydroorotase activity
AM402_RS09590	COG1285	pathogenesis
AM402_RS09610	COG1360	Flagellar Motor Protein
AM402_RS09615	COG2198	Histidine kinase
AM402_RS09615	COG0643	Histidine kinase
AM402_RS09620	COG0835	chemotaxis
AM402_RS09625	COG0840	transmembrane signaling receptor activity
AM402_RS09630	COG0840	transmembrane signaling receptor activity
AM402_RS09640	COG2201	protein-glutamate methylesterase activity
AM402_RS09645	COG0745	RESPONSE REGULATOR receiver
AM402_RS09660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM402_RS09675	COG3210	domain, Protein
AM402_RS09695	COG1815	bacterial-type flagellum-dependent cell motility
AM402_RS09700	COG1558	bacterial-type flagellum-dependent cell motility
AM402_RS09725	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AM402_RS09730	COG1706	bacterial-type flagellum-dependent cell motility
AM402_RS09740	COG1256	bacterial-type flagellum assembly
AM402_RS09755	COG1987	bacterial-type flagellum assembly
AM402_RS09760	COG1338	Plays a role in the flagellum-specific transport system
AM402_RS09780	COG1580	Controls the rotational direction of flagella during chemotaxis
AM402_RS09790	COG2882	bacterial-type flagellum organization
AM402_RS09795	COG1157	protein secretion by the type III secretion system
AM402_RS09810	COG1766	The M ring may be actively involved in energy transduction
AM402_RS09815	COG1677	Flagellar hook-basal body complex protein FliE
AM402_RS09870	COG1191	sigma factor activity
AM402_RS09880	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM402_RS09880	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM402_RS09880	COG0506	proline dehydrogenase activity
AM402_RS09885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM402_RS09895	COG4974	Belongs to the 'phage' integrase family
AM402_RS09915	COG1113	amino acid transport
AM402_RS09930	COG0589	response to stress
AM402_RS09940	COG2226	methyltransferase
AM402_RS09945	COG1971	Probably functions as a manganese efflux pump
AM402_RS09950	COG1760	l-serine dehydratase
AM402_RS09955	COG0494	nUDIX hydrolase
AM402_RS09965	COG3140	Belongs to the UPF0181 family
AM402_RS09980	COG1115	amino acid carrier protein
AM402_RS09985	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM402_RS09990	COG1114	Component of the transport system for branched-chain amino acids
AM402_RS09995	COG0561	phosphatase activity
AM402_RS10010	COG1113	amino acid transport
AM402_RS10030	COG1830	Aldolase
AM402_RS10035	COG1597	lipid kinase activity
AM402_RS10040	COG0826	peptidase U32
AM402_RS10045	COG0745	RESPONSE REGULATOR receiver
AM402_RS10050	COG2205	protein histidine kinase activity
AM402_RS10055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM402_RS10060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM402_RS10065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM402_RS10075	COG0675	Transposase, IS605 OrfB family
AM402_RS10080	COG3104	oligopeptide transport
AM402_RS10105	COG2239	Acts as a magnesium transporter
AM402_RS10115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM402_RS10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM402_RS10125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM402_RS10130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM402_RS10135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM402_RS10140	COG2233	PERMEase
AM402_RS10145	COG0668	transmembrane transport
AM402_RS10150	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM402_RS10155	COG2211	Major facilitator Superfamily
AM402_RS10160	COG1393	Belongs to the ArsC family
AM402_RS10165	COG4783	chaperone-mediated protein folding
AM402_RS10170	COG0628	permease
AM402_RS10175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM402_RS10180	COG2716	regulation of RNA biosynthetic process
AM402_RS10185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM402_RS10190	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM402_RS10195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM402_RS10200	COG2321	neutral zinc metallopeptidase
AM402_RS10205	COG2707	UPF0756 membrane protein
AM402_RS10210	COG1444	tRNA N-acetyltransferase activity
AM402_RS10220	COG2832	Protein of unknown function (DUF454)
AM402_RS10225	COG1876	peptidase activity
AM402_RS10230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM402_RS10235	COG1393	Belongs to the ArsC family
AM402_RS10245	COG2197	response regulator
AM402_RS10250	COG0281	malic enzyme
AM402_RS10250	COG0280	phosphate acetyltransferase
AM402_RS10265	COG1770	oligopeptidase
AM402_RS10270	COG4206	TonB-dependent receptor
AM402_RS10270	COG1629	transport
AM402_RS10275	COG1570	exodeoxyribonuclease VII activity
AM402_RS10280	COG0517	IMP dehydrogenase activity
AM402_RS10280	COG0516	GMP reductase activity
AM402_RS10285	COG0519	Catalyzes the synthesis of GMP from XMP
AM402_RS10285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM402_RS10295	COG0582	viral genome integration into host DNA
AM402_RS10370	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM402_RS10555	COG3541	Predicted nucleotidyltransferase
AM402_RS10570	COG1324	tolerance protein
AM402_RS10575	COG2390	Transcriptional regulator
AM402_RS10580	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM402_RS10585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM402_RS10590	COG3842	ATPase activity
AM402_RS10635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM402_RS10650	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM402_RS10655	COG1494	fructose-1,6-bisphosphatase
AM402_RS10660	COG0778	Nitroreductase
AM402_RS10665	COG2197	response regulator
AM402_RS10670	COG0322	excinuclease ABC activity
AM402_RS10675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM402_RS10705	COG3683	transport system, periplasmic component
AM402_RS10710	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM402_RS10730	COG2076	Multidrug Resistance protein
AM402_RS10740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM402_RS10745	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM402_RS10750	COG2186	Transcriptional regulator
AM402_RS10770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM402_RS10775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM402_RS10780	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM402_RS10785	COG3713	MltA-interacting MipA family protein
AM402_RS10800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM402_RS10805	COG3139	Protein of unknown function (DUF1315)
AM402_RS10810	COG1335	isochorismatase
AM402_RS10815	COG0252	asparaginase activity
AM402_RS10820	COG0616	signal peptide processing
AM402_RS10825	COG0778	Nitroreductase
AM402_RS10830	COG0709	Synthesizes selenophosphate from selenide and ATP
AM402_RS10835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM402_RS10840	COG0708	Exodeoxyribonuclease III
AM402_RS10845	COG0583	DNA-binding transcription factor activity
AM402_RS10855	COG0788	formyltetrahydrofolate deformylase activity
AM402_RS10860	COG3012	SEC-C Motif Domain Protein
AM402_RS10865	COG0745	RESPONSE REGULATOR receiver
AM402_RS10870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM402_RS10885	COG1435	thymidine kinase activity
AM402_RS10890	COG1454	alcohol dehydrogenase
AM402_RS10890	COG1012	belongs to the aldehyde dehydrogenase family
AM402_RS10895	COG2095	MarC family integral membrane protein
AM402_RS10900	COG4608	Belongs to the ABC transporter superfamily
AM402_RS10910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM402_RS10915	COG0601	transmembrane transport
AM402_RS10920	COG4166	transmembrane transport
AM402_RS10925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM402_RS10955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM402_RS10960	COG0444	Belongs to the ABC transporter superfamily
AM402_RS10970	COG1396	sequence-specific DNA binding
AM402_RS10980	COG3539	Fimbrial protein
AM402_RS10990	COG3188	usher protein
AM402_RS11005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM402_RS11010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM402_RS11015	COG1309	transcriptional regulator
AM402_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
AM402_RS11025	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM402_RS11030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM402_RS11035	COG0402	S-adenosylhomocysteine deaminase activity
AM402_RS11045	COG0113	porphobilinogen synthase activity
AM402_RS11065	COG0589	response to stress
AM402_RS11075	COG0589	response to stress
AM402_RS11100	COG2966	Psort location CytoplasmicMembrane, score
AM402_RS11105	COG3610	response to peptide
AM402_RS11115	COG2356	endonuclease I
AM402_RS11125	COG1702	phosphate starvation-inducible protein PhoH
AM402_RS11130	COG3152	Membrane
AM402_RS11145	COG1294	oxidase, subunit
AM402_RS11150	COG1271	oxidase subunit
AM402_RS11155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM402_RS11160	COG1280	lysine exporter protein (LysE YggA)
AM402_RS11170	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM402_RS11175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM402_RS11180	COG4558	Periplasmic binding protein
AM402_RS11185	COG3720	iron ion transport
AM402_RS11190	COG4771	TonB-dependent receptor
AM402_RS11205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM402_RS11210	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM402_RS11215	COG0574	Belongs to the PEP-utilizing enzyme family
AM402_RS11215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM402_RS11220	COG0628	permease
AM402_RS11225	COG0247	lactate metabolic process
AM402_RS11225	COG0277	FAD linked oxidase domain protein
AM402_RS11230	COG2050	protein possibly involved in aromatic compounds catabolism
AM402_RS11240	COG0316	Belongs to the HesB IscA family
AM402_RS11245	COG0719	Fe-S assembly protein
AM402_RS11250	COG0396	ATPase activity
AM402_RS11255	COG0719	Fe-S assembly protein
AM402_RS11260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM402_RS11265	COG2166	iron-sulfur cluster assembly
AM402_RS11270	COG1376	ErfK ybiS ycfS ynhG family protein
AM402_RS11270	COG1388	LysM domain
AM402_RS11285	COG0076	glutamate decarboxylase activity
AM402_RS11290	COG0531	amino acid
AM402_RS11310	COG0534	Mate efflux family protein
AM402_RS11315	COG0307	riboflavin synthase, alpha
AM402_RS11320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM402_RS11325	COG2814	Major facilitator Superfamily
AM402_RS11330	COG0583	DNA-binding transcription factor activity
AM402_RS11335	COG1609	Transcriptional regulator
AM402_RS11345	COG0730	response to heat
AM402_RS11360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM402_RS11365	COG0582	viral genome integration into host DNA
AM402_RS11405	COG3723	Recombinational DNA repair protein, rece pathway
AM402_RS11410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM402_RS11475	COG0305	Participates in initiation and elongation during chromosome replication
AM402_RS11550	COG3772	lysozyme
AM402_RS11735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM402_RS11745	COG0675	Transposase, IS605 OrfB family
AM402_RS11750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM402_RS11755	COG0346	lactoylglutathione lyase activity
AM402_RS11760	COG3313	Fe-S protein
AM402_RS11775	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM402_RS11780	COG0259	pyridoxamine-phosphate oxidase activity
AM402_RS11785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM402_RS11800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM402_RS11810	COG4172	Belongs to the ABC transporter superfamily
AM402_RS11815	COG4171	peptide transport system, permease
AM402_RS11825	COG4166	transmembrane transport
AM402_RS11830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AM402_RS11835	COG1842	Phage shock protein A
AM402_RS11845	COG1983	PspC domain protein
AM402_RS11855	COG3106	COG3106 Predicted ATPase
AM402_RS11860	COG3768	UPF0283 membrane protein
AM402_RS11875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM402_RS11880	COG4166	transmembrane transport
AM402_RS11895	COG0598	Magnesium transport protein CorA
AM402_RS11915	COG0346	lactoylglutathione lyase activity
AM402_RS11930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM402_RS11950	COG2917	probably involved in intracellular septation
AM402_RS11965	COG3047	cAMP biosynthetic process
AM402_RS11975	COG0159	tryptophan synthase activity
AM402_RS11980	COG0133	tryptophan synthase activity
AM402_RS11990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM402_RS11995	COG0512	Glutamine amidotransferase of anthranilate synthase
AM402_RS12000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM402_RS12010	COG0009	L-threonylcarbamoyladenylate synthase
AM402_RS12015	COG1187	pseudouridine synthase activity
AM402_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
AM402_RS12035	COG0616	signal peptide processing
AM402_RS12045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM402_RS12060	COG3501	Rhs element vgr protein
AM402_RS12095	COG0583	DNA-binding transcription factor activity
AM402_RS12105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM402_RS12115	COG1464	Belongs to the NlpA lipoprotein family
AM402_RS12120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM402_RS12125	COG0671	phosphoesterase, PA-phosphatase related
AM402_RS12130	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM402_RS12135	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM402_RS12140	COG0284	orotidine-5'-phosphate decarboxylase activity
AM402_RS12145	COG0023	Translation Initiation Factor
AM402_RS12150	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AM402_RS12155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM402_RS12165	COG4659	FMN binding
AM402_RS12175	COG4656	Part of a membrane complex involved in electron transport
AM402_RS12185	COG4657	Part of a membrane complex involved in electron transport
AM402_RS12195	COG0673	inositol 2-dehydrogenase activity
AM402_RS12200	COG0385	Bile acid
AM402_RS12205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM402_RS12215	COG5339	Protein conserved in bacteria
AM402_RS12220	COG0114	fumarate hydratase activity
AM402_RS12230	COG2814	Major facilitator Superfamily
AM402_RS12235	COG0583	DNA-binding transcription factor activity
AM402_RS12240	COG1940	carbohydrate kinase activity
AM402_RS12245	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM402_RS12260	COG4221	oxidoreductase activity
AM402_RS12300	COG3157	Type VI secretion system effector, Hcp
AM402_RS12330	COG1609	Transcriptional regulator
AM402_RS12330	COG2207	Transcriptional regulator
AM402_RS12335	COG0436	Aminotransferase
AM402_RS12340	COG1757	Na H antiporter
AM402_RS12345	COG2115	Belongs to the xylose isomerase family
AM402_RS12350	COG1070	Carbohydrate kinase
AM402_RS12370	COG0443	Heat shock 70 kDa protein
AM402_RS12380	COG1538	Outer membrane efflux protein
AM402_RS12385	COG1289	transmembrane transporter activity
AM402_RS12400	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM402_RS12405	COG0477	Major facilitator Superfamily
AM402_RS12415	COG2814	Major facilitator Superfamily
AM402_RS12425	COG0402	S-adenosylhomocysteine deaminase activity
AM402_RS12430	COG1671	Belongs to the UPF0178 family
AM402_RS12435	COG0488	(ABC) transporter
AM402_RS12445	COG1309	transcriptional regulator
AM402_RS12455	COG0583	DNA-binding transcription factor activity
AM402_RS12465	COG2814	Major facilitator Superfamily
AM402_RS12485	COG1464	Belongs to the NlpA lipoprotein family
AM402_RS12505	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM402_RS12510	COG0488	(ABC) transporter
AM402_RS12515	COG3097	Belongs to the UPF0267 family
AM402_RS12520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM402_RS12520	COG2169	Transcriptional regulator
AM402_RS12525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM402_RS12545	COG0251	oxidation-reduction process
AM402_RS12555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM402_RS12565	COG2376	Dihydroxyacetone kinase
AM402_RS12585	COG1349	DNA-binding transcription factor activity
AM402_RS12590	COG0243	molybdopterin cofactor binding
AM402_RS12595	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS12600	COG3302	dmso reductase anchor subunit
AM402_RS12605	COG3381	protein complex oligomerization
AM402_RS12610	COG0590	tRNA wobble adenosine to inosine editing
AM402_RS12615	COG0666	response to abiotic stimulus
AM402_RS12620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM402_RS12625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM402_RS12630	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM402_RS12635	COG2205	protein histidine kinase activity
AM402_RS12640	COG0745	RESPONSE REGULATOR receiver
AM402_RS12645	COG0842	Transport permease protein
AM402_RS12650	COG1129	ABC transporter
AM402_RS12650	COG0842	Transport permease protein
AM402_RS12655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM402_RS12665	COG4974	Belongs to the 'phage' integrase family
AM402_RS12670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM402_RS12700	COG3634	alkyl hydroperoxide reductase activity
AM402_RS12715	COG1695	Transcriptional regulator
AM402_RS12725	COG0604	alcohol dehydrogenase
AM402_RS12725	COG1028	Short-chain dehydrogenase reductase Sdr
AM402_RS12725	COG3321	synthase
AM402_RS12740	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS12745	COG0243	molybdopterin cofactor binding
AM402_RS12750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM402_RS12755	COG0589	response to stress
AM402_RS12760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM402_RS12765	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM402_RS12775	COG0531	amino acid
AM402_RS12785	COG3121	Chaperone
AM402_RS12790	COG3188	usher protein
AM402_RS12805	COG1643	Atp-dependent helicase
AM402_RS12825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM402_RS12835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM402_RS12860	COG3784	Protein of unknown function (DUF1318)
AM402_RS12870	COG2911	Protein conserved in bacteria
AM402_RS12875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM402_RS12890	COG3708	Transcriptional regulator
AM402_RS12890	COG2207	Transcriptional regulator
AM402_RS12900	COG4619	ABC transporter
AM402_RS12905	COG0390	transport system, permease component
AM402_RS12910	COG2983	Belongs to the UPF0260 family
AM402_RS12915	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM402_RS12920	COG2951	lytic endotransglycosylase activity
AM402_RS12925	COG3100	YcgL domain-containing protein
AM402_RS12930	COG0850	regulation of cytokinetic process
AM402_RS12935	COG2894	cell division
AM402_RS12940	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM402_RS12945	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM402_RS12950	COG0318	PFAM AMP-dependent synthetase and ligase
AM402_RS12955	COG3065	identical protein binding
AM402_RS12965	COG1199	ATP-dependent helicase activity
AM402_RS12970	COG0251	oxidation-reduction process
AM402_RS12975	COG0702	epimerase
AM402_RS12980	COG2076	Multidrug Resistance protein
AM402_RS12985	COG2076	Multidrug Resistance protein
AM402_RS12990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM402_RS12995	COG1737	Transcriptional regulator
AM402_RS13000	COG0469	pyruvate kinase activity
AM402_RS13005	COG1560	Kdo2-lipid A biosynthetic process
AM402_RS13010	COG0739	heme binding
AM402_RS13015	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM402_RS13020	COG1121	(ABC) transporter
AM402_RS13025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM402_RS13030	COG2255	four-way junction helicase activity
AM402_RS13035	COG0632	four-way junction helicase activity
AM402_RS13040	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM402_RS13045	COG0217	transcriptional regulatory protein
AM402_RS13050	COG0494	nUDIX hydrolase
AM402_RS13055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM402_RS13060	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM402_RS13065	COG2226	methyltransferase
AM402_RS13070	COG0500	methyltransferase
AM402_RS13075	COG0488	(ABC) transporter
AM402_RS13085	COG3142	Participates in the control of copper homeostasis
AM402_RS13090	COG3102	Protein conserved in bacteria
AM402_RS13095	COG0018	arginyl-trna synthetase
AM402_RS13105	COG0728	peptidoglycan biosynthetic process
AM402_RS13110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM402_RS13115	COG0477	Major facilitator Superfamily
AM402_RS13125	COG3381	protein complex oligomerization
AM402_RS13140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM402_RS13150	COG0659	secondary active sulfate transmembrane transporter activity
AM402_RS13160	COG1242	4 iron, 4 sulfur cluster binding
AM402_RS13165	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM402_RS13170	COG2912	Transglutaminase-like superfamily
AM402_RS13180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM402_RS13185	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM402_RS13190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM402_RS13195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM402_RS13200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM402_RS13210	COG0193	aminoacyl-tRNA hydrolase activity
AM402_RS13215	COG0012	GTP binding
AM402_RS13280	COG0586	Pfam SNARE associated Golgi protein
AM402_RS13295	COG2186	Transcriptional regulator
AM402_RS13300	COG0579	oxidoreductase
AM402_RS13305	COG2207	Transcriptional regulator
AM402_RS13310	COG0095	Lipoate-protein ligase
AM402_RS13315	COG0791	NLP P60 protein
AM402_RS13320	COG2076	Multidrug Resistance protein
AM402_RS13325	COG2076	Multidrug Resistance protein
AM402_RS13330	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM402_RS13335	COG0726	polysaccharide deacetylase
AM402_RS13340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM402_RS13340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM402_RS13345	COG0463	Glycosyl transferase, family 2
AM402_RS13350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM402_RS13355	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AM402_RS13360	COG4139	cobalamin transport
AM402_RS13365	COG0776	regulation of translation
AM402_RS13370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM402_RS13370	COG0072	phenylalanine-tRNA ligase activity
AM402_RS13375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM402_RS13380	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM402_RS13385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM402_RS13390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM402_RS13395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM402_RS13400	COG3539	Fimbrial protein
AM402_RS13410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM402_RS13430	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM402_RS13435	COG1121	(ABC) transporter
AM402_RS13440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM402_RS13445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM402_RS13450	COG3001	Fructosamine kinase
AM402_RS13460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM402_RS13465	COG1988	membrane-bound metal-dependent
AM402_RS13470	COG1823	symporter activity
AM402_RS13480	COG0501	Belongs to the peptidase M48B family
AM402_RS13500	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM402_RS13505	COG1956	GAF domain-containing protein
AM402_RS13510	COG2995	paraquat-inducible protein a
AM402_RS13515	COG3008	intermembrane lipid transfer
AM402_RS13530	COG1276	copper resistance
AM402_RS13535	COG2372	response to copper ion
AM402_RS13540	COG1528	Iron-storage protein
AM402_RS13560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AM402_RS13565	COG1598	PFAM Uncharacterised protein family UPF0150
AM402_RS13570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AM402_RS13580	COG0024	Methionine aminopeptidase
AM402_RS13610	COG2841	Protein conserved in bacteria
AM402_RS13615	COG3272	Protein of unknown function (DUF1722)
AM402_RS13625	COG0500	methyltransferase
AM402_RS13630	COG3969	phosphoadenosine phosphosulfate
AM402_RS13635	COG1475	DNA binding
AM402_RS13655	COG0572	uridine kinase
AM402_RS13665	COG0702	epimerase
AM402_RS13670	COG1733	regulation of RNA biosynthetic process
AM402_RS13680	COG0071	Belongs to the small heat shock protein (HSP20) family
AM402_RS13685	COG1278	Cold shock
AM402_RS13705	COG0538	isocitrate dehydrogenase activity
AM402_RS13840	COG1802	Transcriptional regulator
AM402_RS13840	COG4626	Terminase
AM402_RS13860	COG3772	lysozyme
AM402_RS13875	COG1917	Cupin 2, conserved barrel domain protein
AM402_RS13875	COG4977	sequence-specific DNA binding
AM402_RS13880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM402_RS13885	COG3477	response to acidic pH
AM402_RS13890	COG1278	Cold shock
AM402_RS13900	COG1403	HNH endonuclease
AM402_RS13930	COG4197	protein conserved in bacteria, prophage-related
AM402_RS13950	COG5532	Uncharacterized conserved protein (DUF2303)
AM402_RS13955	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM402_RS13965	COG0582	viral genome integration into host DNA
AM402_RS13970	COG0538	isocitrate dehydrogenase activity
AM402_RS14070	COG0740	serine-type endopeptidase activity
AM402_RS14075	COG4695	Portal protein
AM402_RS14080	COG4626	Terminase
AM402_RS14080	COG1802	Transcriptional regulator
AM402_RS14110	COG3772	lysozyme
AM402_RS14155	COG1403	HNH endonuclease
AM402_RS14175	COG4725	Belongs to the MT-A70-like family
AM402_RS14220	COG5532	Uncharacterized conserved protein (DUF2303)
AM402_RS14225	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM402_RS14235	COG0582	viral genome integration into host DNA
AM402_RS14240	COG0538	isocitrate dehydrogenase activity
AM402_RS14245	COG1187	pseudouridine synthase activity
AM402_RS14255	COG0482	sulfurtransferase activity
AM402_RS14260	COG2915	High frequency lysogenization protein hflD homolog
AM402_RS14265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM402_RS14270	COG0745	RESPONSE REGULATOR receiver
AM402_RS14275	COG2205	protein histidine kinase activity
AM402_RS14280	COG2850	peptidyl-arginine hydroxylation
AM402_RS14300	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM402_RS14310	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM402_RS14315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM402_RS14320	COG3134	Outer membrane lipoprotein
AM402_RS14325	COG1252	NADH dehydrogenase
AM402_RS14335	COG1472	Belongs to the glycosyl hydrolase 3 family
AM402_RS14345	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM402_RS14350	COG5633	Lipoprotein
AM402_RS14355	COG0537	adenosine 5'-monophosphoramidase activity
AM402_RS14360	COG0084	hydrolase, TatD family'
AM402_RS14365	COG0470	DNA polymerase III
AM402_RS14370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM402_RS14375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM402_RS14380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM402_RS14385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM402_RS14390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM402_RS14405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM402_RS14410	COG0416	fatty acid biosynthetic process
AM402_RS14415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM402_RS14420	COG1399	metal-binding, possibly nucleic acid-binding protein
AM402_RS14425	COG0424	maF-like protein
AM402_RS14435	COG0564	pseudouridine synthase activity
AM402_RS14440	COG1530	ribonuclease E activity
AM402_RS14445	COG2926	Belongs to the UPF0265 family
AM402_RS14450	COG2211	Major facilitator Superfamily
AM402_RS14455	COG2925	Exonuclease
AM402_RS14460	COG0277	FAD linked oxidase domain protein
AM402_RS14465	COG0583	DNA-binding transcription factor activity
AM402_RS14470	COG3961	Belongs to the TPP enzyme family
AM402_RS14480	COG0531	amino acid
AM402_RS14490	COG4771	TonB-dependent receptor
AM402_RS14495	COG0833	amino acid
AM402_RS14500	COG0583	DNA-binding transcription factor activity
AM402_RS14505	COG2855	membrane
AM402_RS14510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM402_RS14515	COG0494	nUDIX hydrolase
AM402_RS14525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM402_RS14540	COG0671	phosphoesterase, PA-phosphatase related
AM402_RS14545	COG0791	NLP P60 protein
AM402_RS14555	COG2814	Major facilitator Superfamily
AM402_RS14560	COG1187	pseudouridine synthase activity
AM402_RS14565	COG1061	Type III restriction enzyme res subunit
AM402_RS14570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM402_RS14575	COG3081	Nucleoid-associated protein
AM402_RS14580	COG3082	Protein of unknown function (DUF1414)
AM402_RS14585	COG3083	sulfuric ester hydrolase activity
AM402_RS14740	COG3772	lysozyme
AM402_RS14800	COG0305	Participates in initiation and elongation during chromosome replication
AM402_RS14805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM402_RS14810	COG1802	Transcriptional regulator
AM402_RS14810	COG4626	Terminase
AM402_RS14885	COG1280	lysine exporter protein (LysE YggA)
AM402_RS14900	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM402_RS14915	COG1560	Kdo2-lipid A biosynthetic process
AM402_RS14920	COG1278	Cold shock
AM402_RS14935	COG2207	Transcriptional regulator
AM402_RS14935	COG3708	Transcriptional regulator
AM402_RS14945	COG0656	L-ascorbic acid biosynthetic process
AM402_RS14950	COG0583	DNA-binding transcription factor activity
AM402_RS14965	COG3615	Tellurite resistance protein tehB
AM402_RS14975	COG0456	acetyltransferase
AM402_RS14985	COG2920	part of a sulfur-relay system
AM402_RS14990	COG1254	Belongs to the acylphosphatase family
AM402_RS14995	COG3785	DNA binding
AM402_RS15000	COG1832	CoA-binding protein
AM402_RS15005	COG1803	Methylglyoxal synthase
AM402_RS15010	COG0210	DNA helicase
AM402_RS15015	COG1289	transmembrane transporter activity
AM402_RS15020	COG3070	regulator of competence-specific genes
AM402_RS15030	COG2885	chlorophyll binding
AM402_RS15030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM402_RS15035	COG3120	sequence-specific DNA binding
AM402_RS15040	COG1067	ATP-dependent peptidase activity
AM402_RS15045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM402_RS15050	COG3130	regulation of translation
AM402_RS15060	COG3009	Protein conserved in bacteria
AM402_RS15065	COG3008	intermembrane lipid transfer
AM402_RS15065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM402_RS15070	COG2995	paraquat-inducible protein a
AM402_RS15075	COG0488	(ABC) transporter
AM402_RS15080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM402_RS15080	COG0116	Belongs to the methyltransferase superfamily
AM402_RS15085	COG3217	Mosc domain protein beta barrel domain protein
AM402_RS15085	COG0633	Ferredoxin
AM402_RS15095	COG0167	dihydroorotate dehydrogenase activity
AM402_RS15105	COG0308	aminopeptidase N
AM402_RS15110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM402_RS15120	COG0017	Asparaginyl-tRNA synthetase
AM402_RS15125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM402_RS15130	COG1448	Aminotransferase
AM402_RS15240	COG3501	Rhs element vgr protein
AM402_RS15330	COG3157	Type VI secretion system effector, Hcp
AM402_RS15335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM402_RS15340	COG3108	Peptidase M15
AM402_RS15345	COG2989	Protein conserved in bacteria
AM402_RS15350	COG3700	Belongs to the class B bacterial acid phosphatase family
AM402_RS15360	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM402_RS15365	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM402_RS15370	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AM402_RS15375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM402_RS15380	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM402_RS15385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM402_RS15390	COG2835	tetraacyldisaccharide 4'-kinase activity
AM402_RS15400	COG1663	tetraacyldisaccharide 4'-kinase activity
AM402_RS15405	COG1132	(ABC) transporter
AM402_RS15410	COG2333	competence protein COMEC
AM402_RS15410	COG0658	competence protein
AM402_RS15415	COG0776	regulation of translation
AM402_RS15420	COG0539	negative regulation of cytoplasmic translation
AM402_RS15425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM402_RS15430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM402_RS15435	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM402_RS15445	COG3210	domain, Protein
AM402_RS15450	COG0252	asparaginase activity
AM402_RS15455	COG1944	ATP diphosphatase activity
AM402_RS15460	COG2116	formate transmembrane transporter activity
AM402_RS15465	COG1882	Formate acetyltransferase
AM402_RS15470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM402_RS15480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM402_RS15490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM402_RS15495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM402_RS15500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM402_RS15505	COG3107	peptidoglycan biosynthetic process
AM402_RS15505	COG1674	ftsk spoiiie
AM402_RS15515	COG0492	ferredoxin-NADP+ reductase activity
AM402_RS15525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM402_RS15530	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM402_RS15535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM402_RS15540	COG0542	response to heat
AM402_RS15545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM402_RS15550	COG1278	Cold shock
AM402_RS15555	COG0577	efflux transmembrane transporter activity
AM402_RS15555	COG1136	(ABC) transporter
AM402_RS15560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM402_RS15565	COG3593	DNA synthesis involved in DNA repair
AM402_RS15570	COG2431	L-lysine efflux transmembrane transporter activity
AM402_RS15575	COG0702	epimerase
AM402_RS15580	COG1126	abc transporter atp-binding protein
AM402_RS15585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM402_RS15590	COG4215	(ABC) transporter
AM402_RS15595	COG4160	amino acid transport
AM402_RS15600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM402_RS15615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM402_RS15620	COG0432	Pfam Uncharacterised protein family UPF0047
AM402_RS15625	COG0671	phosphoesterase, PA-phosphatase related
AM402_RS15630	COG0814	amino acid
AM402_RS15635	COG1760	l-serine dehydratase
AM402_RS15640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AM402_RS15645	COG1686	Belongs to the peptidase S11 family
AM402_RS15650	COG0625	glutathione transferase activity
AM402_RS15655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM402_RS15660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM402_RS15665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM402_RS15675	COG0131	Imidazoleglycerol-phosphate dehydratase
AM402_RS15675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM402_RS15680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM402_RS15685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM402_RS15690	COG0107	imidazoleglycerol-phosphate synthase activity
AM402_RS15695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM402_RS15695	COG0140	phosphoribosyl-ATP diphosphatase activity
AM402_RS15700	COG1454	alcohol dehydrogenase
AM402_RS15705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM402_RS15710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM402_RS15715	COG1253	flavin adenine dinucleotide binding
AM402_RS15720	COG3069	C4-dicarboxylate transmembrane transporter activity
AM402_RS15725	COG2982	Protein involved in outer membrane biogenesis
AM402_RS15730	COG0717	Belongs to the dCTP deaminase family
AM402_RS15735	COG0572	uridine kinase
AM402_RS15740	COG0489	protein tyrosine kinase activity
AM402_RS15745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM402_RS15745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM402_RS15750	COG1380	Effector of murein hydrolase LrgA
AM402_RS15755	COG1346	cytolysis
AM402_RS15760	COG0295	cytidine deaminase activity
AM402_RS15765	COG0281	malic enzyme
AM402_RS15770	COG2949	membrane
AM402_RS15775	COG2311	Membrane
AM402_RS15780	COG0302	gtp cyclohydrolase
AM402_RS15785	COG0477	Major facilitator Superfamily
AM402_RS15795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM402_RS15830	COG0583	DNA-binding transcription factor activity
AM402_RS15835	COG2079	MmgE PrpD family protein
AM402_RS15850	COG3069	C4-dicarboxylate transmembrane transporter activity
AM402_RS15860	COG2897	thiosulfate sulfurtransferase activity
AM402_RS15875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM402_RS15880	COG0513	Belongs to the DEAD box helicase family
AM402_RS15885	COG1309	transcriptional regulator
AM402_RS15895	COG1131	(ABC) transporter
AM402_RS15900	COG0842	Transport permease protein
AM402_RS15905	COG0842	Transport permease protein
AM402_RS15910	COG0670	Belongs to the BI1 family
AM402_RS15915	COG0314	molybdopterin synthase activity
AM402_RS15920	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM402_RS15925	COG0315	cyclic pyranopterin monophosphate synthase activity
AM402_RS15930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM402_RS15935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM402_RS15945	COG0556	nucleotide-excision repair
AM402_RS15955	COG2226	methyltransferase
AM402_RS15960	COG0156	8-amino-7-oxononanoate synthase activity
AM402_RS15965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM402_RS15975	COG2706	6-phosphogluconolactonase activity
AM402_RS15980	COG0561	phosphatase activity
AM402_RS15985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM402_RS15990	COG4149	molybdate abc transporter
AM402_RS15995	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM402_RS16005	COG2005	Transcriptional regulator
AM402_RS16005	COG3585	molybdate ion transport
AM402_RS16050	COG2831	hemolysin activation secretion protein
AM402_RS16055	COG1119	ATPase activity
AM402_RS16060	COG0588	phosphoglycerate mutase activity
AM402_RS16065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM402_RS16090	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM402_RS16095	COG2885	chlorophyll binding
AM402_RS16100	COG0823	Involved in the tonB-independent uptake of proteins
AM402_RS16105	COG3064	Membrane
AM402_RS16110	COG0848	biopolymer transport protein
AM402_RS16115	COG0811	peptide transport
AM402_RS16120	COG0824	Thioesterase
AM402_RS16130	COG0477	Major facilitator Superfamily
AM402_RS16135	COG0583	DNA-binding transcription factor activity
AM402_RS16140	COG3790	cyd operon protein YbgE
AM402_RS16145	COG4890	Cyd operon protein YbgT
AM402_RS16150	COG1294	oxidase, subunit
AM402_RS16155	COG1271	oxidase subunit
AM402_RS16160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM402_RS16165	COG0045	succinate-CoA ligase (ADP-forming) activity
AM402_RS16170	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM402_RS16175	COG0567	Dehydrogenase, E1 component
AM402_RS16185	COG1053	succinate dehydrogenase
AM402_RS16190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM402_RS16210	COG2814	Major facilitator Superfamily
AM402_RS16220	COG0714	Associated with various cellular activities
AM402_RS16225	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM402_RS16230	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM402_RS16240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM402_RS16255	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AM402_RS16260	COG4807	Protein conserved in bacteria
AM402_RS16265	COG0033	Phosphoglucomutase
AM402_RS16270	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM402_RS16275	COG0596	Alpha beta hydrolase
AM402_RS16285	COG0716	FMN binding
AM402_RS16290	COG0735	belongs to the Fur family
AM402_RS16305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM402_RS16510	COG3772	lysozyme
AM402_RS16525	COG3477	response to acidic pH
AM402_RS16555	COG0305	Participates in initiation and elongation during chromosome replication
AM402_RS16625	COG3646	Phage regulatory protein
AM402_RS16650	COG0582	viral genome integration into host DNA
AM402_RS16660	COG0363	glucosamine-6-phosphate deaminase activity
AM402_RS16665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM402_RS16670	COG1940	carbohydrate kinase activity
AM402_RS16670	COG1846	Transcriptional regulator
AM402_RS16720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM402_RS16725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM402_RS16730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM402_RS16735	COG1702	phosphate starvation-inducible protein PhoH
AM402_RS16740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM402_RS16750	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM402_RS16760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM402_RS16785	COG0765	amino acid transport
AM402_RS16790	COG0765	amino acid transport
AM402_RS16795	COG1126	abc transporter atp-binding protein
AM402_RS16800	COG0495	leucyl-tRNA aminoacylation
AM402_RS16805	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AM402_RS16810	COG1466	dna polymerase III delta subunit
AM402_RS16815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM402_RS16825	COG0799	negative regulation of ribosome biogenesis
AM402_RS16830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM402_RS16835	COG0768	penicillin binding
AM402_RS16840	COG0772	Belongs to the SEDS family
AM402_RS16845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM402_RS16850	COG1686	Belongs to the peptidase S11 family
AM402_RS16860	COG0321	lipoyl(octanoyl) transferase activity
AM402_RS16865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM402_RS16870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM402_RS16885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM402_RS16895	COG1780	Probably involved in ribonucleotide reductase function
AM402_RS16910	COG4175	Glycine betaine
AM402_RS16915	COG4176	ABC-type proline glycine betaine transport system permease component
AM402_RS16920	COG2113	Glycine betaine
AM402_RS16925	COG1629	transport
AM402_RS16930	COG2814	Major facilitator Superfamily
AM402_RS16935	COG1846	Transcriptional regulator
AM402_RS16940	COG1335	isochorismatase
AM402_RS16945	COG2814	Major facilitator Superfamily
AM402_RS16955	COG1566	PFAM secretion protein HlyD family protein
AM402_RS16960	COG2814	Major facilitator Superfamily
AM402_RS16965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM402_RS16970	COG5160	protein modification by small protein removal
AM402_RS16975	COG3148	PFAM DTW domain containing protein
AM402_RS16980	COG0045	succinate-CoA ligase (ADP-forming) activity
AM402_RS16980	COG1042	CoA-binding domain protein
AM402_RS16980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM402_RS16985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM402_RS16990	COG5544	Lipoprotein
AM402_RS17020	COG0542	response to heat
AM402_RS17025	COG1496	oxidoreductase activity
AM402_RS17030	COG0564	pseudouridine synthase activity
AM402_RS17035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM402_RS17040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM402_RS17045	COG0077	Prephenate dehydratase
AM402_RS17045	COG1605	Chorismate mutase
AM402_RS17050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM402_RS17055	COG0287	Prephenate dehydrogenase
AM402_RS17055	COG1605	Chorismate mutase
AM402_RS17060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM402_RS17065	COG0335	large ribosomal subunit rRNA binding
AM402_RS17070	COG0336	Belongs to the RNA methyltransferase TrmD family
AM402_RS17080	COG0228	four-way junction DNA binding
AM402_RS17085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM402_RS17090	COG4137	Cytochrome C assembly protein
AM402_RS17095	COG4536	flavin adenine dinucleotide binding
AM402_RS17100	COG1854	S-ribosylhomocysteine lyase activity
AM402_RS17105	COG2918	glutathione biosynthetic process
AM402_RS17135	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM402_RS17140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM402_RS17145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM402_RS17150	COG1546	Belongs to the CinA family
AM402_RS17155	COG2814	Major facilitator Superfamily
AM402_RS17160	COG0204	Acyl-transferase
AM402_RS17160	COG0318	PFAM AMP-dependent synthetase and ligase
AM402_RS17165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM402_RS17170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM402_RS17175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM402_RS17185	COG1073	alpha beta
AM402_RS17190	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM402_RS17195	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM402_RS17200	COG4774	siderophore transport
AM402_RS17205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM402_RS17215	COG3237	CsbD-like
AM402_RS17220	COG2991	Protein conserved in bacteria
AM402_RS17225	COG1477	protein flavinylation
AM402_RS17230	COG2871	sodium ion transport
AM402_RS17235	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM402_RS17240	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM402_RS17245	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM402_RS17250	COG1805	sodium ion transport
AM402_RS17255	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM402_RS17260	COG3034	peptidoglycan biosynthetic process
AM402_RS17265	COG0121	glutamine amidotransferase
AM402_RS17270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM402_RS17275	COG1960	acyl-CoA dehydrogenase activity
AM402_RS17285	COG0583	DNA-binding transcription factor activity
AM402_RS17290	COG0583	DNA-binding transcription factor activity
AM402_RS17310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM402_RS17315	COG0189	ligase activity
AM402_RS17320	COG1678	Uncharacterized ACR, COG1678
AM402_RS17325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM402_RS17330	COG2805	Type II/IV secretion system protein
AM402_RS17335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM402_RS17340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM402_RS17345	COG0762	integral membrane protein
AM402_RS17350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM402_RS17355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM402_RS17360	COG4607	ABC-type enterochelin transport system periplasmic component
AM402_RS17370	COG2066	Belongs to the glutaminase family
AM402_RS17375	COG3171	Protein conserved in bacteria
AM402_RS17385	COG1194	a g-specific adenine glycosylase
AM402_RS17390	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AM402_RS17395	COG0741	lytic transglycosylase activity
AM402_RS17405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM402_RS17520	COG3210	domain, Protein
AM402_RS17525	COG2831	hemolysin activation secretion protein
AM402_RS17680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM402_RS17720	COG0305	Participates in initiation and elongation during chromosome replication
AM402_RS17735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM402_RS17795	COG5290	Psort location Cytoplasmic, score
AM402_RS17885	COG1196	nuclear chromosome segregation
AM402_RS17910	COG1982	Orn Lys Arg decarboxylase major
AM402_RS17915	COG0531	amino acid
AM402_RS17920	COG1309	transcriptional regulator
AM402_RS17930	COG2274	protein secretion by the type I secretion system
AM402_RS17965	COG3708	Transcriptional regulator
AM402_RS17965	COG2207	Transcriptional regulator
AM402_RS18030	COG1263	PTS System
AM402_RS18030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS18035	COG1554	hydrolase, family 65, central catalytic
AM402_RS18040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM402_RS18105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM402_RS18110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM402_RS18120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM402_RS18135	COG3539	Fimbrial protein
AM402_RS18155	COG3188	usher protein
AM402_RS18165	COG3539	Fimbrial protein
AM402_RS18170	COG0582	viral genome integration into host DNA
AM402_RS18190	COG3539	Fimbrial protein
AM402_RS18195	COG3539	Fimbrial protein
AM402_RS18200	COG3121	Chaperone
AM402_RS18205	COG3188	usher protein
AM402_RS18210	COG3539	Fimbrial protein
AM402_RS18215	COG1234	tRNA 3'-trailer cleavage
AM402_RS18230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM402_RS18235	COG1846	Transcriptional regulator
AM402_RS18250	COG3104	oligopeptide transport
AM402_RS18255	COG2314	TM2 domain
AM402_RS18265	COG0126	phosphoglycerate kinase activity
AM402_RS18270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM402_RS18275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM402_RS18290	COG2814	Major facilitator Superfamily
AM402_RS18295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM402_RS18300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM402_RS18305	COG0019	diaminopimelate decarboxylase activity
AM402_RS18315	COG4264	IucA IucC family
AM402_RS18325	COG1120	ATPase activity
AM402_RS18330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM402_RS18365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM402_RS18370	COG0328	RNA-DNA hybrid ribonuclease activity
AM402_RS18375	COG2226	methyltransferase
AM402_RS18380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM402_RS18385	COG0741	lytic transglycosylase activity
AM402_RS18385	COG1388	LysM domain
AM402_RS18390	COG3961	Belongs to the TPP enzyme family
AM402_RS18395	COG0471	metal ion transport
AM402_RS18400	COG0148	phosphopyruvate hydratase activity
AM402_RS18405	COG0504	CTP synthase activity
AM402_RS18415	COG3956	TIGRFAM MazG family protein
AM402_RS18420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM402_RS18425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM402_RS18435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM402_RS18445	COG0316	Belongs to the HesB IscA family
AM402_RS18450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM402_RS18455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM402_RS18460	COG1643	Atp-dependent helicase
AM402_RS18465	COG1489	DNA binding
AM402_RS18485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM402_RS18490	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM402_RS18495	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM402_RS18500	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM402_RS18510	COG3851	Histidine kinase
AM402_RS18515	COG2271	Major facilitator Superfamily
AM402_RS18520	COG1840	ABC-type Fe3 transport system, periplasmic component
AM402_RS18530	COG3842	ATPase activity
AM402_RS18535	COG3048	D-serine ammonia-lyase activity
AM402_RS18540	COG2610	gluconate transmembrane transporter activity
AM402_RS18545	COG0583	DNA-binding transcription factor activity
AM402_RS18550	COG0754	glutathionylspermidine amidase activity
AM402_RS18565	COG4633	Protein conserved in bacteria
AM402_RS18580	COG2837	iron assimilation
AM402_RS18590	COG0243	molybdopterin cofactor binding
AM402_RS18595	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS18610	COG0501	Belongs to the peptidase M48B family
AM402_RS18620	COG0477	Major facilitator Superfamily
AM402_RS18625	COG0842	Transport permease protein
AM402_RS18630	COG1131	(ABC) transporter
AM402_RS18635	COG0288	reversible hydration of carbon dioxide
AM402_RS18645	COG2132	Multicopper oxidase
AM402_RS18680	COG5441	Belongs to the UPF0261 family
AM402_RS18685	COG5564	TIM-barrel signal transduction protein
AM402_RS18690	COG0673	inositol 2-dehydrogenase activity
AM402_RS18695	COG0534	Mate efflux family protein
AM402_RS18705	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM402_RS18710	COG3069	C4-dicarboxylate transmembrane transporter activity
AM402_RS18720	COG0523	cobalamin synthesis protein
AM402_RS18725	COG2879	small protein
AM402_RS18730	COG1966	Carbon starvation protein
AM402_RS18735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM402_RS18740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AM402_RS18750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM402_RS18765	COG1196	nuclear chromosome segregation
AM402_RS18765	COG3264	Mechanosensitive ion channel
AM402_RS18770	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM402_RS18780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM402_RS18785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM402_RS18805	COG1946	Acyl-CoA thioesterase
AM402_RS18810	COG0004	ammonium transporteR
AM402_RS18815	COG0347	Belongs to the P(II) protein family
AM402_RS18820	COG1132	(ABC) transporter
AM402_RS18825	COG1132	(ABC) transporter
AM402_RS18830	COG1522	sequence-specific DNA binding
AM402_RS18835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM402_RS18840	COG0824	Thioesterase
AM402_RS18845	COG1596	polysaccharide export
AM402_RS18845	COG1555	photosystem II stabilization
AM402_RS18850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM402_RS18855	COG0776	regulation of translation
AM402_RS18860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM402_RS18865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM402_RS18870	COG0740	serine-type endopeptidase activity
AM402_RS18875	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM402_RS18880	COG0271	Belongs to the BolA IbaG family
AM402_RS18885	COG3056	Lipoprotein
AM402_RS18890	COG2223	nitrite transmembrane transporter activity
AM402_RS18895	COG0513	Belongs to the DEAD box helicase family
AM402_RS18905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM402_RS18910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM402_RS18915	COG1845	cytochrome c oxidase, subunit III
AM402_RS18920	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM402_RS18925	COG0109	protoheme IX farnesyltransferase activity
AM402_RS18930	COG2814	Major facilitator Superfamily
AM402_RS18935	COG1666	GTP binding
AM402_RS18940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM402_RS18945	COG0693	protein deglycase activity
AM402_RS18960	COG0301	tRNA thio-modification
AM402_RS18960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM402_RS18970	COG0142	geranyltranstransferase activity
AM402_RS18975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM402_RS18980	COG1869	D-ribose catabolic process
AM402_RS18985	COG1129	ABC transporter
AM402_RS18990	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM402_RS18995	COG1879	ABC-type sugar transport system periplasmic component
AM402_RS19000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM402_RS19005	COG1609	Transcriptional regulator
AM402_RS19010	COG2824	Alkylphosphonate utilization operon protein PhnA
AM402_RS19015	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM402_RS19020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM402_RS19025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM402_RS19030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM402_RS19030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM402_RS19035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM402_RS19040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM402_RS19045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM402_RS19050	COG1862	Preprotein translocase
AM402_RS19055	COG0343	queuine tRNA-ribosyltransferase activity
AM402_RS19060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM402_RS19065	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AM402_RS19070	COG0450	alkyl hydroperoxide reductase
AM402_RS19080	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS19085	COG2414	aldehyde ferredoxin oxidoreductase
AM402_RS19095	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS19100	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM402_RS19135	COG1114	Component of the transport system for branched-chain amino acids
AM402_RS19140	COG5002	protein histidine kinase activity
AM402_RS19150	COG0420	3'-5' exonuclease activity
AM402_RS19155	COG0419	ATPase involved in DNA repair
AM402_RS19165	COG0675	Transposase, IS605 OrfB family
AM402_RS19175	COG0737	Belongs to the 5'-nucleotidase family
AM402_RS19180	COG3719	Belongs to the RNase T2 family
AM402_RS19185	COG0737	Belongs to the 5'-nucleotidase family
AM402_RS19195	COG2974	May be involved in recombination
AM402_RS19200	COG0425	Belongs to the sulfur carrier protein TusA family
AM402_RS19205	COG2391	methyltransferase activity
AM402_RS19210	COG0309	Hydrogenase expression formation protein (HypE)
AM402_RS19215	COG0409	Hydrogenase expression formation protein
AM402_RS19220	COG0298	carbon dioxide binding
AM402_RS19225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM402_RS19230	COG1773	rubredoxin
AM402_RS19235	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM402_RS19240	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM402_RS19245	COG5557	Pfam Polysulphide reductase, NrfD
AM402_RS19250	COG0437	4 iron, 4 sulfur cluster binding
AM402_RS19255	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM402_RS19260	COG0848	biopolymer transport protein
AM402_RS19265	COG0811	peptide transport
AM402_RS19270	COG0626	cystathionine gamma-synthase activity
AM402_RS19280	COG2226	methyltransferase
AM402_RS19285	COG1979	alcohol dehydrogenase
AM402_RS19295	COG1388	LysM domain
AM402_RS19295	COG1470	cell adhesion involved in biofilm formation
AM402_RS19315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM402_RS19320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM402_RS19325	COG1047	Peptidyl-prolyl cis-trans
AM402_RS19330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM402_RS19335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM402_RS19340	COG0196	riboflavin kinase activity
AM402_RS19345	COG0268	Binds directly to 16S ribosomal RNA
AM402_RS19350	COG0583	DNA-binding transcription factor activity
AM402_RS19355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM402_RS19360	COG0484	heat shock protein binding
AM402_RS19365	COG0443	Heat shock 70 kDa protein
AM402_RS19370	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM402_RS19380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM402_RS19385	COG3022	response to hydroperoxide
AM402_RS19400	COG0083	homoserine kinase activity
AM402_RS19410	COG0745	RESPONSE REGULATOR receiver
AM402_RS19415	COG3045	CreA protein
AM402_RS19420	COG2207	Transcriptional regulator
AM402_RS19420	COG3708	Transcriptional regulator
AM402_RS19425	COG0406	alpha-ribazole phosphatase activity
AM402_RS19430	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AM402_RS19435	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AM402_RS19440	COG0741	lytic transglycosylase activity
AM402_RS19445	COG0488	(ABC) transporter
AM402_RS19455	COG0675	Transposase, IS605 OrfB family
AM402_RS19465	COG1595	DNA-templated transcription, initiation
AM402_RS19475	COG4771	TonB-dependent receptor
AM402_RS19480	COG4178	(ABC) transporter
AM402_RS19485	COG0612	Peptidase, M16
AM402_RS19495	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM402_RS19495	COG1902	pentaerythritol trinitrate reductase activity
AM402_RS19500	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM402_RS19505	COG0586	Pfam SNARE associated Golgi protein
AM402_RS19510	COG4575	ribosome binding
AM402_RS19515	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM402_RS19525	COG2259	Doxx family
AM402_RS19530	COG0583	DNA-binding transcription factor activity
AM402_RS19535	COG1741	Belongs to the pirin family
AM402_RS19545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM402_RS19555	COG0792	nuclease activity
AM402_RS19560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM402_RS19565	COG2823	Periplasmic or secreted lipoprotein
AM402_RS19570	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM402_RS19575	COG0830	nickel cation binding
AM402_RS19580	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM402_RS19585	COG0804	urea catabolic process
AM402_RS19590	COG0832	Belongs to the urease beta subunit family
AM402_RS19595	COG0831	urea catabolic process
AM402_RS19600	COG0829	nickel cation binding
AM402_RS19605	COG2207	Transcriptional regulator
AM402_RS19610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM402_RS19615	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM402_RS19620	COG5002	protein histidine kinase activity
AM402_RS19620	COG2198	Histidine kinase
AM402_RS19620	COG0784	Response regulator, receiver
AM402_RS19625	COG0067	glutamate synthase
AM402_RS19625	COG0069	glutamate synthase activity
AM402_RS19625	COG0070	glutamate synthase
AM402_RS19630	COG0493	'glutamate synthase
AM402_RS19635	COG3069	C4-dicarboxylate transmembrane transporter activity
AM402_RS19640	COG1473	amidohydrolase
AM402_RS19650	COG2969	positive regulation of protein catabolic process
AM402_RS19655	COG0625	glutathione transferase activity
AM402_RS19660	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM402_RS19665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM402_RS19670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM402_RS19675	COG3105	Protein conserved in bacteria
AM402_RS19680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM402_RS19685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM402_RS19695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM402_RS19700	COG5007	Belongs to the BolA IbaG family
AM402_RS19710	COG2854	intermembrane phospholipid transfer
AM402_RS19715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM402_RS19720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM402_RS19725	COG1127	ABC transporter
AM402_RS19730	COG0530	calcium, potassium:sodium antiporter activity
AM402_RS19735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM402_RS19735	COG0517	IMP dehydrogenase activity
AM402_RS19740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM402_RS19745	COG3117	lipopolysaccharide transmembrane transporter activity
AM402_RS19750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM402_RS19755	COG1137	ATPase activity
AM402_RS19760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM402_RS19765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM402_RS19775	COG1660	Displays ATPase and GTPase activities
AM402_RS19780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM402_RS19785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM402_RS19790	COG0312	modulator of DNA gyrase
AM402_RS19795	COG3028	Belongs to the UPF0307 family
AM402_RS19800	COG2732	(Barnase) inhibitor
AM402_RS19810	COG0312	modulator of DNA gyrase
AM402_RS19815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM402_RS19820	COG3164	Protein of unknown function
AM402_RS19825	COG1530	ribonuclease E activity
AM402_RS19830	COG0424	maF-like protein
AM402_RS19835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM402_RS19840	COG1792	Involved in formation and maintenance of cell shape
AM402_RS19845	COG1077	Cell shape determining protein MreB Mrl
AM402_RS19850	COG0604	alcohol dehydrogenase
AM402_RS19855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM402_RS19860	COG0511	ligase activity, forming carbon-carbon bonds
AM402_RS19865	COG0439	Biotin carboxylase
AM402_RS19870	COG3924	membrane
AM402_RS19875	COG4145	pantothenate transmembrane transporter activity
AM402_RS19880	COG2264	protein methyltransferase activity
AM402_RS19885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM402_RS19890	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM402_RS19915	COG2807	transmembrane transport
AM402_RS19920	COG0584	glycerophosphoryl diester phosphodiesterase
AM402_RS19925	COG1653	transport
AM402_RS19935	COG0395	ABC-type sugar transport system, permease component
AM402_RS19940	COG3842	ATPase activity
AM402_RS19945	COG0501	Belongs to the peptidase M48B family
AM402_RS19950	COG1846	Transcriptional regulator
AM402_RS19955	COG2814	Major facilitator Superfamily
AM402_RS19965	COG1929	Belongs to the glycerate kinase type-1 family
AM402_RS19975	COG2177	Part of the ABC transporter FtsEX involved in
AM402_RS19980	COG2884	Cell division ATP-binding protein ftsE
AM402_RS19985	COG0552	protein localization to endoplasmic reticulum
AM402_RS19990	COG0742	ribosomal rna small subunit methyltransferase
AM402_RS19995	COG3776	membrane
AM402_RS20005	COG3714	YhhN family
AM402_RS20010	COG2217	Heavy metal translocating P-type atpase
AM402_RS20025	COG0675	Transposase, IS605 OrfB family
AM402_RS20035	COG0425	Belongs to the sulfur carrier protein TusA family
AM402_RS20045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM402_RS20055	COG0247	lactate metabolic process
AM402_RS20065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM402_RS20070	COG2271	Major facilitator Superfamily
AM402_RS20075	COG0584	glycerophosphoryl diester phosphodiesterase
AM402_RS20080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM402_RS20085	COG1053	succinate dehydrogenase
AM402_RS20090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM402_RS20095	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM402_RS20100	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM402_RS20105	COG2076	Multidrug Resistance protein
AM402_RS20110	COG0298	carbon dioxide binding
AM402_RS20115	COG0375	protein maturation
AM402_RS20120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM402_RS20125	COG3604	Transcriptional regulator
AM402_RS20140	COG2194	sulfuric ester hydrolase activity
AM402_RS20145	COG1304	FMN binding
AM402_RS20150	COG2181	nitrate reductase activity
AM402_RS20155	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM402_RS20160	COG1140	nitrate reductase beta subunit
AM402_RS20165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM402_RS20170	COG2223	nitrite transmembrane transporter activity
AM402_RS20175	COG3850	Histidine kinase
AM402_RS20180	COG2197	response regulator
AM402_RS20185	COG0583	DNA-binding transcription factor activity
AM402_RS20200	COG0730	response to heat
AM402_RS20205	COG4770	biotin carboxylase activity
AM402_RS20210	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM402_RS20215	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AM402_RS20220	COG1914	H( )-stimulated, divalent metal cation uptake system
AM402_RS20255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM402_RS20260	COG1739	Uncharacterized protein family UPF0029
AM402_RS20265	COG0006	proline dipeptidase activity
AM402_RS20270	COG1024	Enoyl-CoA hydratase
AM402_RS20270	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM402_RS20275	COG0183	Belongs to the thiolase family
AM402_RS20285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM402_RS20300	COG0805	protein transport
AM402_RS20305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM402_RS20310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM402_RS20320	COG3165	ubiquinone biosynthetic process from chorismate
AM402_RS20325	COG2226	methyltransferase
AM402_RS20330	COG1322	Protein conserved in bacteria
AM402_RS20335	COG0586	Pfam SNARE associated Golgi protein
AM402_RS20340	COG2365	Tyrosine phosphatase family
AM402_RS20350	COG3753	Protein conserved in bacteria
AM402_RS20360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM402_RS20365	COG0583	DNA-binding transcription factor activity
AM402_RS20375	COG0025	NhaP-type Na H and K H
AM402_RS20380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM402_RS20385	COG2252	PERMEase
AM402_RS20405	COG0440	acetolactate synthase activity
AM402_RS20410	COG0028	Belongs to the TPP enzyme family
AM402_RS20430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM402_RS20430	COG1263	PTS System
AM402_RS20435	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM402_RS20445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM402_RS20450	COG1349	DNA-binding transcription factor activity
AM402_RS20455	COG1690	Belongs to the RtcB family
AM402_RS20460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM402_RS20475	COG0675	Transposase, IS605 OrfB family
AM402_RS20485	COG0582	viral genome integration into host DNA
AM402_RS20495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM402_RS20500	COG0795	lipopolysaccharide-transporting ATPase activity
AM402_RS20505	COG0795	lipopolysaccharide-transporting ATPase activity
AM402_RS20510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM402_RS20515	COG2927	DNA polymerase III (CHI subunit)
AM402_RS20520	COG0525	valine-tRNA ligase activity
AM402_RS20525	COG0456	acetyltransferase
AM402_RS20540	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AM402_RS20545	COG0675	Transposase, IS605 OrfB family
AM402_RS20550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM402_RS20560	COG0540	Belongs to the ATCase OTCase family
AM402_RS20565	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AM402_RS20570	COG0251	oxidation-reduction process
AM402_RS20580	COG1328	CTP reductase activity
AM402_RS20585	COG0602	queuosine metabolic process
AM402_RS20610	COG2827	Endonuclease containing a URI domain
AM402_RS20615	COG3153	acetyltransferase
AM402_RS20620	COG3154	lipid carrier protein
AM402_RS20625	COG0826	peptidase U32
AM402_RS20735	COG3385	transposase activity
AM402_RS20765	COG0633	Ferredoxin
AM402_RS20810	COG3385	transposase activity
AM402_RS20825	COG0629	single-stranded DNA binding
AM402_RS20835	COG0714	Associated with various cellular activities
AM402_RS20870	COG5001	Diguanylate cyclase
AM402_RS20895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM402_RS20985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM402_RS21085	COG1192	Involved in chromosome partitioning
AM402_RS21105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM402_RS21120	COG0583	DNA-binding transcription factor activity
AM402_RS21170	COG0798	PFAM Bile acid sodium symporter
AM402_RS21200	COG2948	multi-organism process
AM402_RS21215	COG3701	Conjugal transfer protein
AM402_RS21235	COG3451	type IV secretory pathway VirB4
AM402_RS21245	COG3838	Conjugal transfer protein Trbc
AM402_RS21250	COG4962	Type ii secretion system protein e
AM402_RS21310	COG4227	nucleotidyltransferase activity
AM402_RS21360	COG1487	ribonuclease activity
AM402_RS21395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM402_RS21495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM402_RS21580	COG3039	Transposase
AM402_RS21625	COG0616	signal peptide processing
AM402_RS21765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM402_RS21840	COG5001	Diguanylate cyclase
AM402_RS21840	COG3300	MHYT domain
AM402_RS21940	COG0789	Transcriptional regulator
AM402_RS21955	COG4974	Belongs to the 'phage' integrase family