locus-tag	class	description
AM403_RS00025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM403_RS00035	COG0616	signal peptide processing
AM403_RS00040	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS00055	COG1187	pseudouridine synthase activity
AM403_RS00060	COG0009	L-threonylcarbamoyladenylate synthase
AM403_RS00070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM403_RS00075	COG0512	Glutamine amidotransferase of anthranilate synthase
AM403_RS00080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM403_RS00090	COG0133	tryptophan synthase activity
AM403_RS00095	COG0159	tryptophan synthase activity
AM403_RS00105	COG3047	cAMP biosynthetic process
AM403_RS00120	COG2917	probably involved in intracellular septation
AM403_RS00140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM403_RS00155	COG0346	lactoylglutathione lyase activity
AM403_RS00175	COG0598	Magnesium transport protein CorA
AM403_RS00190	COG4166	transmembrane transport
AM403_RS00195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AM403_RS00210	COG3768	UPF0283 membrane protein
AM403_RS00215	COG3106	COG3106 Predicted ATPase
AM403_RS00225	COG1983	PspC domain protein
AM403_RS00235	COG1842	Phage shock protein A
AM403_RS00245	COG4166	transmembrane transport
AM403_RS00255	COG4171	peptide transport system, permease
AM403_RS00260	COG4172	Belongs to the ABC transporter superfamily
AM403_RS00270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM403_RS00285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM403_RS00290	COG0259	pyridoxamine-phosphate oxidase activity
AM403_RS00295	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM403_RS00310	COG3313	Fe-S protein
AM403_RS00315	COG0346	lactoylglutathione lyase activity
AM403_RS00320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM403_RS00325	COG0675	Transposase, IS605 OrfB family
AM403_RS00335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM403_RS00340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM403_RS00355	COG0730	response to heat
AM403_RS00365	COG1609	Transcriptional regulator
AM403_RS00370	COG0583	DNA-binding transcription factor activity
AM403_RS00375	COG2814	Major facilitator Superfamily
AM403_RS00380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM403_RS00385	COG0307	riboflavin synthase, alpha
AM403_RS00390	COG0534	Mate efflux family protein
AM403_RS00410	COG0531	amino acid
AM403_RS00415	COG0076	glutamate decarboxylase activity
AM403_RS00430	COG1376	ErfK ybiS ycfS ynhG family protein
AM403_RS00430	COG1388	LysM domain
AM403_RS00435	COG2166	iron-sulfur cluster assembly
AM403_RS00440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM403_RS00445	COG0719	Fe-S assembly protein
AM403_RS00450	COG0396	ATPase activity
AM403_RS00455	COG0719	Fe-S assembly protein
AM403_RS00460	COG0316	Belongs to the HesB IscA family
AM403_RS00470	COG2050	protein possibly involved in aromatic compounds catabolism
AM403_RS00475	COG0277	FAD linked oxidase domain protein
AM403_RS00475	COG0247	lactate metabolic process
AM403_RS00480	COG0628	permease
AM403_RS00485	COG0574	Belongs to the PEP-utilizing enzyme family
AM403_RS00485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM403_RS00490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM403_RS00495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM403_RS00510	COG4771	TonB-dependent receptor
AM403_RS00515	COG3720	iron ion transport
AM403_RS00520	COG4558	Periplasmic binding protein
AM403_RS00525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM403_RS00530	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM403_RS00540	COG1280	lysine exporter protein (LysE YggA)
AM403_RS00545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM403_RS00550	COG1271	oxidase subunit
AM403_RS00555	COG1294	oxidase, subunit
AM403_RS00570	COG3152	Membrane
AM403_RS00575	COG1702	phosphate starvation-inducible protein PhoH
AM403_RS00585	COG2356	endonuclease I
AM403_RS00595	COG3610	response to peptide
AM403_RS00600	COG2966	Psort location CytoplasmicMembrane, score
AM403_RS00625	COG0589	response to stress
AM403_RS00635	COG0589	response to stress
AM403_RS00655	COG0113	porphobilinogen synthase activity
AM403_RS00665	COG0402	S-adenosylhomocysteine deaminase activity
AM403_RS00670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM403_RS00675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM403_RS00680	COG1012	belongs to the aldehyde dehydrogenase family
AM403_RS00685	COG1309	transcriptional regulator
AM403_RS00690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM403_RS00695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM403_RS00710	COG3188	usher protein
AM403_RS00720	COG3539	Fimbrial protein
AM403_RS00730	COG1396	sequence-specific DNA binding
AM403_RS00740	COG0444	Belongs to the ABC transporter superfamily
AM403_RS00745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM403_RS00775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM403_RS00780	COG4166	transmembrane transport
AM403_RS00785	COG0601	transmembrane transport
AM403_RS00790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM403_RS00800	COG4608	Belongs to the ABC transporter superfamily
AM403_RS00805	COG2095	MarC family integral membrane protein
AM403_RS00810	COG1012	belongs to the aldehyde dehydrogenase family
AM403_RS00810	COG1454	alcohol dehydrogenase
AM403_RS00815	COG1435	thymidine kinase activity
AM403_RS00830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM403_RS00835	COG0745	RESPONSE REGULATOR receiver
AM403_RS00840	COG3012	SEC-C Motif Domain Protein
AM403_RS00845	COG0788	formyltetrahydrofolate deformylase activity
AM403_RS00855	COG0583	DNA-binding transcription factor activity
AM403_RS00860	COG0708	Exodeoxyribonuclease III
AM403_RS00865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM403_RS00870	COG0709	Synthesizes selenophosphate from selenide and ATP
AM403_RS00875	COG0778	Nitroreductase
AM403_RS00880	COG0616	signal peptide processing
AM403_RS00885	COG0252	asparaginase activity
AM403_RS00890	COG1335	isochorismatase
AM403_RS00895	COG3139	Protein of unknown function (DUF1315)
AM403_RS00900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM403_RS00915	COG3713	MltA-interacting MipA family protein
AM403_RS00920	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AM403_RS00925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM403_RS00930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM403_RS00935	COG2186	Transcriptional regulator
AM403_RS00940	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM403_RS00945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AM403_RS00955	COG2076	Multidrug Resistance protein
AM403_RS00975	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AM403_RS00980	COG3683	transport system, periplasmic component
AM403_RS01010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM403_RS01015	COG0322	excinuclease ABC activity
AM403_RS01020	COG2197	response regulator
AM403_RS01025	COG0778	Nitroreductase
AM403_RS01030	COG1494	fructose-1,6-bisphosphatase
AM403_RS01035	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AM403_RS01050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM403_RS01095	COG3842	ATPase activity
AM403_RS01100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM403_RS01105	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM403_RS01110	COG2390	Transcriptional regulator
AM403_RS01115	COG1324	tolerance protein
AM403_RS01130	COG3541	Predicted nucleotidyltransferase
AM403_RS01135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM403_RS01135	COG0519	Catalyzes the synthesis of GMP from XMP
AM403_RS01140	COG0516	GMP reductase activity
AM403_RS01140	COG0517	IMP dehydrogenase activity
AM403_RS01145	COG1570	exodeoxyribonuclease VII activity
AM403_RS01150	COG4206	TonB-dependent receptor
AM403_RS01150	COG1629	transport
AM403_RS01155	COG1770	oligopeptidase
AM403_RS01170	COG0281	malic enzyme
AM403_RS01170	COG0280	phosphate acetyltransferase
AM403_RS01175	COG2197	response regulator
AM403_RS01185	COG1393	Belongs to the ArsC family
AM403_RS01190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM403_RS01195	COG1876	peptidase activity
AM403_RS01200	COG2832	Protein of unknown function (DUF454)
AM403_RS01210	COG1444	tRNA N-acetyltransferase activity
AM403_RS01215	COG2707	UPF0756 membrane protein
AM403_RS01220	COG2321	neutral zinc metallopeptidase
AM403_RS01225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM403_RS01230	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM403_RS01235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM403_RS01240	COG2716	regulation of RNA biosynthetic process
AM403_RS01245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM403_RS01250	COG0628	permease
AM403_RS01255	COG4783	chaperone-mediated protein folding
AM403_RS01260	COG1393	Belongs to the ArsC family
AM403_RS01265	COG2211	Major facilitator Superfamily
AM403_RS01270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM403_RS01275	COG0668	transmembrane transport
AM403_RS01280	COG2233	PERMEase
AM403_RS01285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM403_RS01290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM403_RS01295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM403_RS01300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM403_RS01305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM403_RS01315	COG2239	Acts as a magnesium transporter
AM403_RS01335	COG3104	oligopeptide transport
AM403_RS01340	COG0675	Transposase, IS605 OrfB family
AM403_RS01350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM403_RS01355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM403_RS01360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM403_RS01365	COG2205	protein histidine kinase activity
AM403_RS01370	COG0745	RESPONSE REGULATOR receiver
AM403_RS01375	COG0826	peptidase U32
AM403_RS01380	COG1597	lipid kinase activity
AM403_RS01385	COG1830	Aldolase
AM403_RS01405	COG1113	amino acid transport
AM403_RS01420	COG0561	phosphatase activity
AM403_RS01425	COG1114	Component of the transport system for branched-chain amino acids
AM403_RS01430	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM403_RS01435	COG1115	amino acid carrier protein
AM403_RS01450	COG3140	Belongs to the UPF0181 family
AM403_RS01460	COG0494	nUDIX hydrolase
AM403_RS01465	COG1760	l-serine dehydratase
AM403_RS01470	COG1971	Probably functions as a manganese efflux pump
AM403_RS01475	COG2226	methyltransferase
AM403_RS01485	COG0589	response to stress
AM403_RS01500	COG1113	amino acid transport
AM403_RS01510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM403_RS01515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM403_RS01515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM403_RS01515	COG0506	proline dehydrogenase activity
AM403_RS01525	COG1191	sigma factor activity
AM403_RS01580	COG1677	Flagellar hook-basal body complex protein FliE
AM403_RS01585	COG1766	The M ring may be actively involved in energy transduction
AM403_RS01600	COG1157	protein secretion by the type III secretion system
AM403_RS01605	COG2882	bacterial-type flagellum organization
AM403_RS01615	COG1580	Controls the rotational direction of flagella during chemotaxis
AM403_RS01635	COG1338	Plays a role in the flagellum-specific transport system
AM403_RS01640	COG1987	bacterial-type flagellum assembly
AM403_RS01655	COG1256	bacterial-type flagellum assembly
AM403_RS01665	COG1706	bacterial-type flagellum-dependent cell motility
AM403_RS01670	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AM403_RS01695	COG1558	bacterial-type flagellum-dependent cell motility
AM403_RS01700	COG1815	bacterial-type flagellum-dependent cell motility
AM403_RS01720	COG3210	domain, Protein
AM403_RS01730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM403_RS01750	COG0745	RESPONSE REGULATOR receiver
AM403_RS01755	COG2201	protein-glutamate methylesterase activity
AM403_RS01765	COG0840	transmembrane signaling receptor activity
AM403_RS01770	COG0840	transmembrane signaling receptor activity
AM403_RS01775	COG0835	chemotaxis
AM403_RS01780	COG0643	Histidine kinase
AM403_RS01780	COG2198	Histidine kinase
AM403_RS01785	COG1360	Flagellar Motor Protein
AM403_RS01805	COG1285	pathogenesis
AM403_RS01845	COG0418	dihydroorotase activity
AM403_RS01885	COG1560	Kdo2-lipid A biosynthetic process
AM403_RS01890	COG2814	Major facilitator Superfamily
AM403_RS01905	COG1607	acyl-coa hydrolase
AM403_RS01920	COG1902	pentaerythritol trinitrate reductase activity
AM403_RS01945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM403_RS01950	COG1396	sequence-specific DNA binding
AM403_RS01960	COG3247	response to pH
AM403_RS01965	COG0668	transmembrane transport
AM403_RS01975	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS01980	COG3302	dmso reductase anchor subunit
AM403_RS02115	COG2197	response regulator
AM403_RS02120	COG2205	protein histidine kinase activity
AM403_RS02120	COG0784	Response regulator, receiver
AM403_RS02130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM403_RS02135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM403_RS02140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM403_RS02145	COG0633	Ferredoxin
AM403_RS02155	COG0814	amino acid
AM403_RS02175	COG1441	menaquinone biosynthetic process
AM403_RS02180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM403_RS02185	COG0596	Alpha beta hydrolase
AM403_RS02190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM403_RS02195	COG1169	isochorismate synthase
AM403_RS02210	COG1007	ATP synthesis coupled electron transport
AM403_RS02215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM403_RS02220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM403_RS02225	COG0713	ATP synthesis coupled electron transport
AM403_RS02230	COG0839	Belongs to the complex I subunit 6 family
AM403_RS02235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM403_RS02240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM403_RS02250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM403_RS02260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM403_RS02260	COG0649	NAD binding
AM403_RS02265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM403_RS02270	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM403_RS02280	COG0583	DNA-binding transcription factor activity
AM403_RS02285	COG0436	Aminotransferase
AM403_RS02290	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM403_RS02295	COG0471	metal ion transport
AM403_RS02295	COG0490	domain, Protein
AM403_RS02300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM403_RS02305	COG3013	Belongs to the UPF0304 family
AM403_RS02310	COG3092	negative regulation of chromosome organization
AM403_RS02315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM403_RS02320	COG0857	belongs to the CobB CobQ family
AM403_RS02320	COG0280	phosphate acetyltransferase
AM403_RS02355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM403_RS02360	COG1518	maintenance of DNA repeat elements
AM403_RS02390	COG1203	CRISPR-associated helicase, Cas3
AM403_RS02395	COG3037	sugar-specific permease SgaT UlaA
AM403_RS02405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM403_RS02415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM403_RS02420	COG0625	glutathione transferase activity
AM403_RS02425	COG1090	epimerase
AM403_RS02430	COG0163	prenyltransferase activity
AM403_RS02435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM403_RS02440	COG1286	toxin biosynthetic process
AM403_RS02445	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AM403_RS02450	COG0285	dihydrofolate synthase activity
AM403_RS02455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM403_RS02460	COG0586	Pfam SNARE associated Golgi protein
AM403_RS02470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM403_RS02475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM403_RS02480	COG2207	Transcriptional regulator
AM403_RS02485	COG0697	spore germination
AM403_RS02490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM403_RS02495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM403_RS02495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM403_RS02515	COG3101	peptidyl-lysine hydroxylation
AM403_RS02520	COG0730	response to heat
AM403_RS02525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM403_RS02535	COG0783	Belongs to the Dps family
AM403_RS02540	COG2840	Smr protein MutS2
AM403_RS02545	COG2062	phosphohistidine phosphatase, SixA
AM403_RS02550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM403_RS02550	COG1024	Enoyl-CoA hydratase
AM403_RS02555	COG0183	Belongs to the thiolase family
AM403_RS02560	COG3691	Protein conserved in bacteria
AM403_RS02565	COG2067	long-chain fatty acid transport protein
AM403_RS02705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM403_RS02740	COG0305	Participates in initiation and elongation during chromosome replication
AM403_RS02890	COG1396	sequence-specific DNA binding
AM403_RS02930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM403_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS02955	COG3530	Putative quorum-sensing-regulated virulence factor
AM403_RS02960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM403_RS02965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM403_RS02975	COG3115	cell septum assembly
AM403_RS02985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM403_RS02990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM403_RS03000	COG2190	(PTS) system
AM403_RS03005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM403_RS03010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM403_RS03015	COG4208	sulfate ABC transporter
AM403_RS03020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM403_RS03030	COG2837	iron assimilation
AM403_RS03040	COG0456	acetyltransferase
AM403_RS03045	COG0408	coproporphyrinogen oxidase activity
AM403_RS03055	COG1160	GTP binding
AM403_RS03060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM403_RS03065	COG2976	Protein conserved in bacteria
AM403_RS03070	COG0124	histidyl-tRNA synthetase
AM403_RS03075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM403_RS03090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM403_RS03095	COG0105	UTP biosynthetic process
AM403_RS03100	COG4953	penicillin-binding protein 1C
AM403_RS03105	COG2373	Large extracellular alpha-helical protein
AM403_RS03115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM403_RS03120	COG2975	iron-sulfur cluster assembly
AM403_RS03125	COG0633	Ferredoxin
AM403_RS03130	COG0443	Heat shock 70 kDa protein
AM403_RS03135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM403_RS03140	COG0316	Belongs to the HesB IscA family
AM403_RS03145	COG0822	iron-sulfur transferase activity
AM403_RS03150	COG1104	cysteine desulfurase activity
AM403_RS03155	COG1959	2 iron, 2 sulfur cluster binding
AM403_RS03160	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM403_RS03165	COG0483	inositol monophosphate 1-phosphatase activity
AM403_RS03180	COG2814	Major facilitator Superfamily
AM403_RS03185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM403_RS03190	COG1017	nitric oxide dioxygenase activity
AM403_RS03190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM403_RS03200	COG0347	Belongs to the P(II) protein family
AM403_RS03205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM403_RS03205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM403_RS03210	COG2204	response regulator
AM403_RS03215	COG3170	Tfp pilus assembly protein FimV
AM403_RS03220	COG2205	protein histidine kinase activity
AM403_RS03225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM403_RS03225	COG0047	phosphoribosylformylglycinamidine synthase activity
AM403_RS03230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM403_RS03235	COG3539	Fimbrial protein
AM403_RS03240	COG3188	usher protein
AM403_RS03245	COG3121	Chaperone
AM403_RS03250	COG3539	Fimbrial protein
AM403_RS03255	COG3539	Fimbrial protein
AM403_RS03455	COG0305	Participates in initiation and elongation during chromosome replication
AM403_RS03525	COG1280	lysine exporter protein (LysE YggA)
AM403_RS03540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AM403_RS03555	COG1560	Kdo2-lipid A biosynthetic process
AM403_RS03560	COG1278	Cold shock
AM403_RS03575	COG2207	Transcriptional regulator
AM403_RS03575	COG3708	Transcriptional regulator
AM403_RS03585	COG0656	L-ascorbic acid biosynthetic process
AM403_RS03590	COG0583	DNA-binding transcription factor activity
AM403_RS03605	COG3615	Tellurite resistance protein tehB
AM403_RS03615	COG0456	acetyltransferase
AM403_RS03625	COG2920	part of a sulfur-relay system
AM403_RS03630	COG1254	Belongs to the acylphosphatase family
AM403_RS03635	COG3785	DNA binding
AM403_RS03640	COG1832	CoA-binding protein
AM403_RS03645	COG1803	Methylglyoxal synthase
AM403_RS03650	COG0210	DNA helicase
AM403_RS03660	COG3070	regulator of competence-specific genes
AM403_RS03670	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM403_RS03670	COG2885	chlorophyll binding
AM403_RS03675	COG3120	sequence-specific DNA binding
AM403_RS03680	COG1067	ATP-dependent peptidase activity
AM403_RS03685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM403_RS03690	COG3130	regulation of translation
AM403_RS03700	COG3009	Protein conserved in bacteria
AM403_RS03705	COG3008	intermembrane lipid transfer
AM403_RS03705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM403_RS03710	COG2995	paraquat-inducible protein a
AM403_RS03715	COG0488	(ABC) transporter
AM403_RS03720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM403_RS03720	COG0116	Belongs to the methyltransferase superfamily
AM403_RS03725	COG0633	Ferredoxin
AM403_RS03725	COG3217	Mosc domain protein beta barrel domain protein
AM403_RS03735	COG0167	dihydroorotate dehydrogenase activity
AM403_RS03745	COG0308	aminopeptidase N
AM403_RS03750	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM403_RS03760	COG0017	Asparaginyl-tRNA synthetase
AM403_RS03765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AM403_RS03770	COG1448	Aminotransferase
AM403_RS03850	COG3501	Rhs element vgr protein
AM403_RS03940	COG3157	Type VI secretion system effector, Hcp
AM403_RS03945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM403_RS03950	COG3108	Peptidase M15
AM403_RS03955	COG2989	Protein conserved in bacteria
AM403_RS03960	COG3700	Belongs to the class B bacterial acid phosphatase family
AM403_RS03965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM403_RS03970	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AM403_RS03975	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AM403_RS03980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM403_RS03985	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM403_RS03990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM403_RS03995	COG2835	tetraacyldisaccharide 4'-kinase activity
AM403_RS04005	COG1663	tetraacyldisaccharide 4'-kinase activity
AM403_RS04010	COG1132	(ABC) transporter
AM403_RS04015	COG0658	competence protein
AM403_RS04015	COG2333	competence protein COMEC
AM403_RS04020	COG0776	regulation of translation
AM403_RS04025	COG0539	negative regulation of cytoplasmic translation
AM403_RS04030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM403_RS04035	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM403_RS04040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AM403_RS04050	COG3210	domain, Protein
AM403_RS04055	COG0252	asparaginase activity
AM403_RS04060	COG1944	ATP diphosphatase activity
AM403_RS04065	COG2116	formate transmembrane transporter activity
AM403_RS04070	COG1882	Formate acetyltransferase
AM403_RS04075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM403_RS04085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM403_RS04095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM403_RS04100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM403_RS04105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM403_RS04110	COG1674	ftsk spoiiie
AM403_RS04110	COG3107	peptidoglycan biosynthetic process
AM403_RS04120	COG0492	ferredoxin-NADP+ reductase activity
AM403_RS04130	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AM403_RS04135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM403_RS04140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM403_RS04145	COG0542	response to heat
AM403_RS04150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM403_RS04155	COG1278	Cold shock
AM403_RS04160	COG1136	(ABC) transporter
AM403_RS04160	COG0577	efflux transmembrane transporter activity
AM403_RS04165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM403_RS04170	COG3593	DNA synthesis involved in DNA repair
AM403_RS04175	COG2431	L-lysine efflux transmembrane transporter activity
AM403_RS04180	COG0702	epimerase
AM403_RS04185	COG1126	abc transporter atp-binding protein
AM403_RS04190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM403_RS04195	COG4215	(ABC) transporter
AM403_RS04200	COG4160	amino acid transport
AM403_RS04205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM403_RS04220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM403_RS04225	COG0675	Transposase, IS605 OrfB family
AM403_RS04235	COG0432	Pfam Uncharacterised protein family UPF0047
AM403_RS04240	COG0671	phosphoesterase, PA-phosphatase related
AM403_RS04245	COG0814	amino acid
AM403_RS04250	COG1760	l-serine dehydratase
AM403_RS04255	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AM403_RS04260	COG1686	Belongs to the peptidase S11 family
AM403_RS04265	COG0625	glutathione transferase activity
AM403_RS04270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM403_RS04275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM403_RS04280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM403_RS04290	COG0131	Imidazoleglycerol-phosphate dehydratase
AM403_RS04290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM403_RS04295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM403_RS04300	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM403_RS04305	COG0107	imidazoleglycerol-phosphate synthase activity
AM403_RS04310	COG0140	phosphoribosyl-ATP diphosphatase activity
AM403_RS04310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM403_RS04315	COG1454	alcohol dehydrogenase
AM403_RS04320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM403_RS04325	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM403_RS04330	COG1253	flavin adenine dinucleotide binding
AM403_RS04335	COG3069	C4-dicarboxylate transmembrane transporter activity
AM403_RS04340	COG2982	Protein involved in outer membrane biogenesis
AM403_RS04345	COG0717	Belongs to the dCTP deaminase family
AM403_RS04350	COG0572	uridine kinase
AM403_RS04355	COG0489	protein tyrosine kinase activity
AM403_RS04360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM403_RS04360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM403_RS04365	COG1380	Effector of murein hydrolase LrgA
AM403_RS04370	COG1346	cytolysis
AM403_RS04375	COG0295	cytidine deaminase activity
AM403_RS04380	COG0281	malic enzyme
AM403_RS04385	COG2949	membrane
AM403_RS04390	COG2311	Membrane
AM403_RS04395	COG0302	gtp cyclohydrolase
AM403_RS04400	COG0477	Major facilitator Superfamily
AM403_RS04410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM403_RS04445	COG0583	DNA-binding transcription factor activity
AM403_RS04450	COG2079	MmgE PrpD family protein
AM403_RS04465	COG3069	C4-dicarboxylate transmembrane transporter activity
AM403_RS04475	COG2897	thiosulfate sulfurtransferase activity
AM403_RS04485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM403_RS04490	COG0513	Belongs to the DEAD box helicase family
AM403_RS04495	COG1309	transcriptional regulator
AM403_RS04505	COG1131	(ABC) transporter
AM403_RS04510	COG0842	Transport permease protein
AM403_RS04515	COG0842	Transport permease protein
AM403_RS04520	COG0670	Belongs to the BI1 family
AM403_RS04525	COG0314	molybdopterin synthase activity
AM403_RS04530	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM403_RS04535	COG0315	cyclic pyranopterin monophosphate synthase activity
AM403_RS04540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM403_RS04545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM403_RS04555	COG0556	nucleotide-excision repair
AM403_RS04560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM403_RS04565	COG2226	methyltransferase
AM403_RS04570	COG0156	8-amino-7-oxononanoate synthase activity
AM403_RS04575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM403_RS04585	COG2706	6-phosphogluconolactonase activity
AM403_RS04590	COG0561	phosphatase activity
AM403_RS04595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM403_RS04600	COG4149	molybdate abc transporter
AM403_RS04605	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM403_RS04615	COG3585	molybdate ion transport
AM403_RS04615	COG2005	Transcriptional regulator
AM403_RS04630	COG2831	hemolysin activation secretion protein
AM403_RS04635	COG1119	ATPase activity
AM403_RS04640	COG0588	phosphoglycerate mutase activity
AM403_RS04645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM403_RS04670	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM403_RS04675	COG2885	chlorophyll binding
AM403_RS04680	COG0823	Involved in the tonB-independent uptake of proteins
AM403_RS04685	COG3064	Membrane
AM403_RS04690	COG0848	biopolymer transport protein
AM403_RS04695	COG0811	peptide transport
AM403_RS04700	COG0824	Thioesterase
AM403_RS04710	COG0477	Major facilitator Superfamily
AM403_RS04715	COG0583	DNA-binding transcription factor activity
AM403_RS04720	COG3790	cyd operon protein YbgE
AM403_RS04725	COG4890	Cyd operon protein YbgT
AM403_RS04730	COG1294	oxidase, subunit
AM403_RS04735	COG1271	oxidase subunit
AM403_RS04740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM403_RS04745	COG0045	succinate-CoA ligase (ADP-forming) activity
AM403_RS04750	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM403_RS04755	COG0567	Dehydrogenase, E1 component
AM403_RS04765	COG1053	succinate dehydrogenase
AM403_RS04770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM403_RS04790	COG2814	Major facilitator Superfamily
AM403_RS04800	COG0714	Associated with various cellular activities
AM403_RS04805	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM403_RS04810	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM403_RS04820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM403_RS04835	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AM403_RS04840	COG4807	Protein conserved in bacteria
AM403_RS04845	COG0033	Phosphoglucomutase
AM403_RS04850	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AM403_RS04855	COG0596	Alpha beta hydrolase
AM403_RS04865	COG0716	FMN binding
AM403_RS04870	COG0735	belongs to the Fur family
AM403_RS04885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM403_RS05000	COG3620	sequence-specific DNA binding
AM403_RS05070	COG5484	DNA packaging
AM403_RS05070	COG3728	DNA packaging
AM403_RS05095	COG3772	lysozyme
AM403_RS05115	COG1278	Cold shock
AM403_RS05120	COG0071	Belongs to the small heat shock protein (HSP20) family
AM403_RS05145	COG0305	Participates in initiation and elongation during chromosome replication
AM403_RS05275	COG0582	viral genome integration into host DNA
AM403_RS05285	COG0363	glucosamine-6-phosphate deaminase activity
AM403_RS05290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM403_RS05295	COG1940	carbohydrate kinase activity
AM403_RS05295	COG1846	Transcriptional regulator
AM403_RS05345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM403_RS05350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM403_RS05355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM403_RS05360	COG1702	phosphate starvation-inducible protein PhoH
AM403_RS05365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM403_RS05375	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM403_RS05385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM403_RS05410	COG0765	amino acid transport
AM403_RS05415	COG0765	amino acid transport
AM403_RS05420	COG1126	abc transporter atp-binding protein
AM403_RS05425	COG0495	leucyl-tRNA aminoacylation
AM403_RS05430	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AM403_RS05435	COG1466	dna polymerase III delta subunit
AM403_RS05440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM403_RS05450	COG0799	negative regulation of ribosome biogenesis
AM403_RS05455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM403_RS05460	COG0768	penicillin binding
AM403_RS05465	COG0772	Belongs to the SEDS family
AM403_RS05470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM403_RS05475	COG1686	Belongs to the peptidase S11 family
AM403_RS05485	COG0321	lipoyl(octanoyl) transferase activity
AM403_RS05490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM403_RS05495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM403_RS05505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM403_RS05515	COG1780	Probably involved in ribonucleotide reductase function
AM403_RS05530	COG4175	Glycine betaine
AM403_RS05535	COG4176	ABC-type proline glycine betaine transport system permease component
AM403_RS05540	COG2113	Glycine betaine
AM403_RS05545	COG1629	transport
AM403_RS05550	COG2814	Major facilitator Superfamily
AM403_RS05555	COG1846	Transcriptional regulator
AM403_RS05560	COG1566	PFAM secretion protein HlyD family protein
AM403_RS05565	COG2814	Major facilitator Superfamily
AM403_RS05570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM403_RS05575	COG5160	protein modification by small protein removal
AM403_RS05580	COG3148	PFAM DTW domain containing protein
AM403_RS05585	COG1042	CoA-binding domain protein
AM403_RS05585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM403_RS05585	COG0045	succinate-CoA ligase (ADP-forming) activity
AM403_RS05590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM403_RS05595	COG5544	Lipoprotein
AM403_RS05625	COG0542	response to heat
AM403_RS05630	COG1496	oxidoreductase activity
AM403_RS05635	COG0564	pseudouridine synthase activity
AM403_RS05640	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM403_RS05645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM403_RS05650	COG0077	Prephenate dehydratase
AM403_RS05650	COG1605	Chorismate mutase
AM403_RS05655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM403_RS05660	COG1605	Chorismate mutase
AM403_RS05660	COG0287	Prephenate dehydrogenase
AM403_RS05665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM403_RS05675	COG0335	large ribosomal subunit rRNA binding
AM403_RS05680	COG0336	Belongs to the RNA methyltransferase TrmD family
AM403_RS05690	COG0228	four-way junction DNA binding
AM403_RS05695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM403_RS05700	COG4137	Cytochrome C assembly protein
AM403_RS05705	COG4536	flavin adenine dinucleotide binding
AM403_RS05710	COG1854	S-ribosylhomocysteine lyase activity
AM403_RS05715	COG2918	glutathione biosynthetic process
AM403_RS05740	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM403_RS05745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM403_RS05750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM403_RS05755	COG1546	Belongs to the CinA family
AM403_RS05760	COG2814	Major facilitator Superfamily
AM403_RS05765	COG0318	PFAM AMP-dependent synthetase and ligase
AM403_RS05765	COG0204	Acyl-transferase
AM403_RS05770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM403_RS05775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM403_RS05780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM403_RS05790	COG1073	alpha beta
AM403_RS05795	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM403_RS05800	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM403_RS05810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM403_RS05820	COG3237	CsbD-like
AM403_RS05825	COG2991	Protein conserved in bacteria
AM403_RS05830	COG1477	protein flavinylation
AM403_RS05835	COG2871	sodium ion transport
AM403_RS05840	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM403_RS05845	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM403_RS05850	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM403_RS05855	COG1805	sodium ion transport
AM403_RS05860	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AM403_RS05865	COG3034	peptidoglycan biosynthetic process
AM403_RS05870	COG0121	glutamine amidotransferase
AM403_RS05875	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM403_RS05880	COG1960	acyl-CoA dehydrogenase activity
AM403_RS05890	COG0583	DNA-binding transcription factor activity
AM403_RS05895	COG0583	DNA-binding transcription factor activity
AM403_RS05915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM403_RS05920	COG0189	ligase activity
AM403_RS05925	COG1678	Uncharacterized ACR, COG1678
AM403_RS05930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM403_RS05935	COG2805	Type II/IV secretion system protein
AM403_RS05940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM403_RS05945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM403_RS05950	COG0762	integral membrane protein
AM403_RS05955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM403_RS05960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM403_RS05965	COG4607	ABC-type enterochelin transport system periplasmic component
AM403_RS05975	COG2066	Belongs to the glutaminase family
AM403_RS05980	COG3171	Protein conserved in bacteria
AM403_RS05990	COG1194	a g-specific adenine glycosylase
AM403_RS05995	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AM403_RS06000	COG0741	lytic transglycosylase activity
AM403_RS06010	COG2801	Transposase and inactivated derivatives
AM403_RS06040	COG1982	Orn Lys Arg decarboxylase major
AM403_RS06045	COG0531	amino acid
AM403_RS06050	COG1309	transcriptional regulator
AM403_RS06060	COG2274	protein secretion by the type I secretion system
AM403_RS06090	COG3708	Transcriptional regulator
AM403_RS06090	COG2207	Transcriptional regulator
AM403_RS06155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS06155	COG1263	PTS System
AM403_RS06160	COG1554	hydrolase, family 65, central catalytic
AM403_RS06165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM403_RS06220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM403_RS06225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM403_RS06235	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AM403_RS06250	COG3539	Fimbrial protein
AM403_RS06270	COG3188	usher protein
AM403_RS06280	COG3539	Fimbrial protein
AM403_RS06285	COG0582	viral genome integration into host DNA
AM403_RS06305	COG3539	Fimbrial protein
AM403_RS06310	COG3539	Fimbrial protein
AM403_RS06315	COG3121	Chaperone
AM403_RS06320	COG3188	usher protein
AM403_RS06325	COG3539	Fimbrial protein
AM403_RS06330	COG1234	tRNA 3'-trailer cleavage
AM403_RS06345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM403_RS06350	COG1846	Transcriptional regulator
AM403_RS06365	COG3104	oligopeptide transport
AM403_RS06370	COG2314	TM2 domain
AM403_RS06380	COG0126	phosphoglycerate kinase activity
AM403_RS06385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM403_RS06390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM403_RS06405	COG2814	Major facilitator Superfamily
AM403_RS06410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM403_RS06415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM403_RS06420	COG0019	diaminopimelate decarboxylase activity
AM403_RS06430	COG4264	IucA IucC family
AM403_RS06440	COG1120	ATPase activity
AM403_RS06445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM403_RS06480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM403_RS06485	COG0328	RNA-DNA hybrid ribonuclease activity
AM403_RS06490	COG2226	methyltransferase
AM403_RS06495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM403_RS06500	COG1388	LysM domain
AM403_RS06500	COG0741	lytic transglycosylase activity
AM403_RS06505	COG3961	Belongs to the TPP enzyme family
AM403_RS06510	COG0471	metal ion transport
AM403_RS06515	COG0148	phosphopyruvate hydratase activity
AM403_RS06520	COG0504	CTP synthase activity
AM403_RS06530	COG3956	TIGRFAM MazG family protein
AM403_RS06535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM403_RS06540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM403_RS06550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM403_RS06560	COG0316	Belongs to the HesB IscA family
AM403_RS06565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM403_RS06570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM403_RS06575	COG1643	Atp-dependent helicase
AM403_RS06580	COG1489	DNA binding
AM403_RS06600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM403_RS06605	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM403_RS06610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM403_RS06615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM403_RS06625	COG3851	Histidine kinase
AM403_RS06630	COG2271	Major facilitator Superfamily
AM403_RS06635	COG1840	ABC-type Fe3 transport system, periplasmic component
AM403_RS06645	COG3842	ATPase activity
AM403_RS06650	COG3048	D-serine ammonia-lyase activity
AM403_RS06655	COG2610	gluconate transmembrane transporter activity
AM403_RS06660	COG0583	DNA-binding transcription factor activity
AM403_RS06665	COG0754	glutathionylspermidine amidase activity
AM403_RS06690	COG2963	transposase activity
AM403_RS06705	COG4633	Protein conserved in bacteria
AM403_RS06720	COG2837	iron assimilation
AM403_RS06730	COG0243	molybdopterin cofactor binding
AM403_RS06735	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS06760	COG0477	Major facilitator Superfamily
AM403_RS06765	COG0842	Transport permease protein
AM403_RS06770	COG1131	(ABC) transporter
AM403_RS06775	COG0288	reversible hydration of carbon dioxide
AM403_RS06785	COG2132	Multicopper oxidase
AM403_RS06820	COG5441	Belongs to the UPF0261 family
AM403_RS06825	COG5564	TIM-barrel signal transduction protein
AM403_RS06830	COG0673	inositol 2-dehydrogenase activity
AM403_RS06835	COG0534	Mate efflux family protein
AM403_RS06845	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM403_RS06850	COG3069	C4-dicarboxylate transmembrane transporter activity
AM403_RS06860	COG0523	cobalamin synthesis protein
AM403_RS06865	COG2879	small protein
AM403_RS06870	COG1966	Carbon starvation protein
AM403_RS06875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM403_RS06880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AM403_RS06890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM403_RS06905	COG3264	Mechanosensitive ion channel
AM403_RS06905	COG1196	nuclear chromosome segregation
AM403_RS06910	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM403_RS06915	COG1309	transcriptional regulator
AM403_RS06920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM403_RS06925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM403_RS06945	COG1946	Acyl-CoA thioesterase
AM403_RS06950	COG0004	ammonium transporteR
AM403_RS06955	COG0347	Belongs to the P(II) protein family
AM403_RS06960	COG1132	(ABC) transporter
AM403_RS06965	COG1132	(ABC) transporter
AM403_RS06970	COG1522	sequence-specific DNA binding
AM403_RS06975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM403_RS06980	COG0824	Thioesterase
AM403_RS06985	COG1596	polysaccharide export
AM403_RS06985	COG1555	photosystem II stabilization
AM403_RS06990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM403_RS06995	COG0776	regulation of translation
AM403_RS07000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM403_RS07005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM403_RS07010	COG0740	serine-type endopeptidase activity
AM403_RS07015	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM403_RS07020	COG0271	Belongs to the BolA IbaG family
AM403_RS07025	COG3056	Lipoprotein
AM403_RS07030	COG2223	nitrite transmembrane transporter activity
AM403_RS07035	COG0513	Belongs to the DEAD box helicase family
AM403_RS07045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM403_RS07050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM403_RS07055	COG1845	cytochrome c oxidase, subunit III
AM403_RS07060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM403_RS07065	COG0109	protoheme IX farnesyltransferase activity
AM403_RS07070	COG2814	Major facilitator Superfamily
AM403_RS07075	COG1666	GTP binding
AM403_RS07080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM403_RS07085	COG0693	protein deglycase activity
AM403_RS07100	COG0301	tRNA thio-modification
AM403_RS07100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM403_RS07110	COG0142	geranyltranstransferase activity
AM403_RS07115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM403_RS07120	COG1869	D-ribose catabolic process
AM403_RS07125	COG1129	ABC transporter
AM403_RS07130	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM403_RS07135	COG1879	ABC-type sugar transport system periplasmic component
AM403_RS07140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM403_RS07145	COG1609	Transcriptional regulator
AM403_RS07160	COG2824	Alkylphosphonate utilization operon protein PhnA
AM403_RS07170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM403_RS07175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM403_RS07180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM403_RS07180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM403_RS07185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM403_RS07190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM403_RS07195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM403_RS07200	COG1862	Preprotein translocase
AM403_RS07205	COG0343	queuine tRNA-ribosyltransferase activity
AM403_RS07210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM403_RS07215	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AM403_RS07220	COG0450	alkyl hydroperoxide reductase
AM403_RS07230	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS07235	COG2414	aldehyde ferredoxin oxidoreductase
AM403_RS07245	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS07250	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM403_RS07305	COG1114	Component of the transport system for branched-chain amino acids
AM403_RS07310	COG5002	protein histidine kinase activity
AM403_RS07320	COG0420	3'-5' exonuclease activity
AM403_RS07325	COG0419	ATPase involved in DNA repair
AM403_RS07345	COG0737	Belongs to the 5'-nucleotidase family
AM403_RS07350	COG3719	Belongs to the RNase T2 family
AM403_RS07355	COG0737	Belongs to the 5'-nucleotidase family
AM403_RS07365	COG2974	May be involved in recombination
AM403_RS07370	COG0425	Belongs to the sulfur carrier protein TusA family
AM403_RS07375	COG2391	methyltransferase activity
AM403_RS07380	COG0309	Hydrogenase expression formation protein (HypE)
AM403_RS07385	COG0409	Hydrogenase expression formation protein
AM403_RS07390	COG0298	carbon dioxide binding
AM403_RS07395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM403_RS07400	COG1773	rubredoxin
AM403_RS07405	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM403_RS07410	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AM403_RS07415	COG5557	Pfam Polysulphide reductase, NrfD
AM403_RS07420	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS07425	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AM403_RS07430	COG0848	biopolymer transport protein
AM403_RS07435	COG0811	peptide transport
AM403_RS07440	COG0626	cystathionine gamma-synthase activity
AM403_RS07450	COG2226	methyltransferase
AM403_RS07455	COG1979	alcohol dehydrogenase
AM403_RS07465	COG1470	cell adhesion involved in biofilm formation
AM403_RS07465	COG1388	LysM domain
AM403_RS07485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM403_RS07490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM403_RS07495	COG1047	Peptidyl-prolyl cis-trans
AM403_RS07500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM403_RS07505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM403_RS07510	COG0196	riboflavin kinase activity
AM403_RS07515	COG0268	Binds directly to 16S ribosomal RNA
AM403_RS07520	COG0583	DNA-binding transcription factor activity
AM403_RS07525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM403_RS07530	COG0484	heat shock protein binding
AM403_RS07535	COG0443	Heat shock 70 kDa protein
AM403_RS07540	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM403_RS07555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM403_RS07560	COG3022	response to hydroperoxide
AM403_RS07575	COG0083	homoserine kinase activity
AM403_RS07585	COG0745	RESPONSE REGULATOR receiver
AM403_RS07590	COG3045	CreA protein
AM403_RS07595	COG3708	Transcriptional regulator
AM403_RS07595	COG2207	Transcriptional regulator
AM403_RS07600	COG0406	alpha-ribazole phosphatase activity
AM403_RS07605	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AM403_RS07610	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AM403_RS07615	COG0741	lytic transglycosylase activity
AM403_RS07620	COG0488	(ABC) transporter
AM403_RS07630	COG1595	DNA-templated transcription, initiation
AM403_RS07640	COG4771	TonB-dependent receptor
AM403_RS07645	COG4178	(ABC) transporter
AM403_RS07650	COG0612	Peptidase, M16
AM403_RS07660	COG1902	pentaerythritol trinitrate reductase activity
AM403_RS07660	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM403_RS07665	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AM403_RS07670	COG0586	Pfam SNARE associated Golgi protein
AM403_RS07675	COG4575	ribosome binding
AM403_RS07680	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AM403_RS07690	COG2259	Doxx family
AM403_RS07695	COG0583	DNA-binding transcription factor activity
AM403_RS07700	COG1741	Belongs to the pirin family
AM403_RS07710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM403_RS07720	COG0792	nuclease activity
AM403_RS07725	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AM403_RS07730	COG2823	Periplasmic or secreted lipoprotein
AM403_RS07735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM403_RS07740	COG0830	nickel cation binding
AM403_RS07745	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM403_RS07750	COG0804	urea catabolic process
AM403_RS07755	COG0832	Belongs to the urease beta subunit family
AM403_RS07760	COG0831	urea catabolic process
AM403_RS07765	COG0829	nickel cation binding
AM403_RS07770	COG2207	Transcriptional regulator
AM403_RS07775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM403_RS07780	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM403_RS07785	COG5002	protein histidine kinase activity
AM403_RS07785	COG0784	Response regulator, receiver
AM403_RS07785	COG2198	Histidine kinase
AM403_RS07790	COG0070	glutamate synthase
AM403_RS07790	COG0069	glutamate synthase activity
AM403_RS07790	COG0067	glutamate synthase
AM403_RS07795	COG0493	'glutamate synthase
AM403_RS07800	COG3069	C4-dicarboxylate transmembrane transporter activity
AM403_RS07805	COG1473	amidohydrolase
AM403_RS07815	COG2969	positive regulation of protein catabolic process
AM403_RS07820	COG0625	glutathione transferase activity
AM403_RS07825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM403_RS07830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM403_RS07835	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM403_RS07840	COG3105	Protein conserved in bacteria
AM403_RS07845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM403_RS07850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM403_RS07860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM403_RS07865	COG5007	Belongs to the BolA IbaG family
AM403_RS07875	COG2854	intermembrane phospholipid transfer
AM403_RS07880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM403_RS07885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM403_RS07890	COG1127	ABC transporter
AM403_RS07895	COG0530	calcium, potassium:sodium antiporter activity
AM403_RS07900	COG0517	IMP dehydrogenase activity
AM403_RS07900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM403_RS07905	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM403_RS07910	COG3117	lipopolysaccharide transmembrane transporter activity
AM403_RS07915	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM403_RS07920	COG1137	ATPase activity
AM403_RS07925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AM403_RS07930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM403_RS07940	COG1660	Displays ATPase and GTPase activities
AM403_RS07945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM403_RS07950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM403_RS07955	COG0312	modulator of DNA gyrase
AM403_RS07960	COG3028	Belongs to the UPF0307 family
AM403_RS07965	COG2732	(Barnase) inhibitor
AM403_RS07975	COG0312	modulator of DNA gyrase
AM403_RS07980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM403_RS07985	COG3164	Protein of unknown function
AM403_RS07990	COG1530	ribonuclease E activity
AM403_RS07995	COG0424	maF-like protein
AM403_RS08000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM403_RS08005	COG1792	Involved in formation and maintenance of cell shape
AM403_RS08010	COG1077	Cell shape determining protein MreB Mrl
AM403_RS08015	COG0604	alcohol dehydrogenase
AM403_RS08020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM403_RS08025	COG0511	ligase activity, forming carbon-carbon bonds
AM403_RS08030	COG0439	Biotin carboxylase
AM403_RS08035	COG3924	membrane
AM403_RS08040	COG4145	pantothenate transmembrane transporter activity
AM403_RS08045	COG2264	protein methyltransferase activity
AM403_RS08050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM403_RS08055	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM403_RS08080	COG2807	transmembrane transport
AM403_RS08085	COG0584	glycerophosphoryl diester phosphodiesterase
AM403_RS08090	COG1653	transport
AM403_RS08100	COG0395	ABC-type sugar transport system, permease component
AM403_RS08105	COG3842	ATPase activity
AM403_RS08110	COG0501	Belongs to the peptidase M48B family
AM403_RS08115	COG1846	Transcriptional regulator
AM403_RS08120	COG2814	Major facilitator Superfamily
AM403_RS08130	COG1929	Belongs to the glycerate kinase type-1 family
AM403_RS08140	COG2177	Part of the ABC transporter FtsEX involved in
AM403_RS08145	COG2884	Cell division ATP-binding protein ftsE
AM403_RS08150	COG0552	protein localization to endoplasmic reticulum
AM403_RS08155	COG0742	ribosomal rna small subunit methyltransferase
AM403_RS08160	COG3776	membrane
AM403_RS08170	COG3714	YhhN family
AM403_RS08175	COG2217	Heavy metal translocating P-type atpase
AM403_RS08190	COG0675	Transposase, IS605 OrfB family
AM403_RS08200	COG0425	Belongs to the sulfur carrier protein TusA family
AM403_RS08210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM403_RS08220	COG0247	lactate metabolic process
AM403_RS08230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM403_RS08235	COG2271	Major facilitator Superfamily
AM403_RS08240	COG0584	glycerophosphoryl diester phosphodiesterase
AM403_RS08245	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM403_RS08250	COG1053	succinate dehydrogenase
AM403_RS08255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM403_RS08260	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM403_RS08265	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AM403_RS08270	COG2076	Multidrug Resistance protein
AM403_RS08275	COG0298	carbon dioxide binding
AM403_RS08280	COG0375	protein maturation
AM403_RS08285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM403_RS08290	COG3604	Transcriptional regulator
AM403_RS08305	COG2194	sulfuric ester hydrolase activity
AM403_RS08310	COG1304	FMN binding
AM403_RS08315	COG2181	nitrate reductase activity
AM403_RS08320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM403_RS08325	COG1140	nitrate reductase beta subunit
AM403_RS08330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM403_RS08335	COG2223	nitrite transmembrane transporter activity
AM403_RS08345	COG2197	response regulator
AM403_RS08350	COG0583	DNA-binding transcription factor activity
AM403_RS08365	COG0730	response to heat
AM403_RS08370	COG4770	biotin carboxylase activity
AM403_RS08375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AM403_RS08380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AM403_RS08385	COG1914	H( )-stimulated, divalent metal cation uptake system
AM403_RS08420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM403_RS08425	COG1739	Uncharacterized protein family UPF0029
AM403_RS08430	COG0006	proline dipeptidase activity
AM403_RS08435	COG1024	Enoyl-CoA hydratase
AM403_RS08435	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM403_RS08440	COG0183	Belongs to the thiolase family
AM403_RS08450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM403_RS08465	COG0805	protein transport
AM403_RS08470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM403_RS08475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM403_RS08485	COG3165	ubiquinone biosynthetic process from chorismate
AM403_RS08490	COG2226	methyltransferase
AM403_RS08495	COG1322	Protein conserved in bacteria
AM403_RS08500	COG0586	Pfam SNARE associated Golgi protein
AM403_RS08505	COG2365	Tyrosine phosphatase family
AM403_RS08515	COG3753	Protein conserved in bacteria
AM403_RS08525	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM403_RS08530	COG0583	DNA-binding transcription factor activity
AM403_RS08540	COG0025	NhaP-type Na H and K H
AM403_RS08545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM403_RS08550	COG2252	PERMEase
AM403_RS08570	COG0440	acetolactate synthase activity
AM403_RS08575	COG0028	Belongs to the TPP enzyme family
AM403_RS08595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS08595	COG1263	PTS System
AM403_RS08600	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM403_RS08610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM403_RS08615	COG1349	DNA-binding transcription factor activity
AM403_RS08620	COG1690	Belongs to the RtcB family
AM403_RS08625	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM403_RS08640	COG0675	Transposase, IS605 OrfB family
AM403_RS08650	COG0582	viral genome integration into host DNA
AM403_RS08665	COG2378	regulation of single-species biofilm formation
AM403_RS08680	COG3596	GTP binding
AM403_RS08730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM403_RS08765	COG0582	viral genome integration into host DNA
AM403_RS08775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM403_RS08780	COG0795	lipopolysaccharide-transporting ATPase activity
AM403_RS08785	COG0795	lipopolysaccharide-transporting ATPase activity
AM403_RS08790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM403_RS08795	COG2927	DNA polymerase III (CHI subunit)
AM403_RS08800	COG0525	valine-tRNA ligase activity
AM403_RS08805	COG0456	acetyltransferase
AM403_RS08820	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AM403_RS08825	COG0675	Transposase, IS605 OrfB family
AM403_RS08835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM403_RS08845	COG0540	Belongs to the ATCase OTCase family
AM403_RS08850	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AM403_RS08855	COG0251	oxidation-reduction process
AM403_RS08865	COG1328	CTP reductase activity
AM403_RS08870	COG0602	queuosine metabolic process
AM403_RS08895	COG2827	Endonuclease containing a URI domain
AM403_RS08900	COG3153	acetyltransferase
AM403_RS08905	COG3154	lipid carrier protein
AM403_RS08910	COG0826	peptidase U32
AM403_RS08915	COG0826	peptidase U32
AM403_RS08920	COG3539	Fimbrial protein
AM403_RS08925	COG3539	Fimbrial protein
AM403_RS08930	COG3539	Fimbrial protein
AM403_RS08935	COG3188	usher protein
AM403_RS08940	COG3121	Chaperone
AM403_RS08945	COG3539	Fimbrial protein
AM403_RS08960	COG1566	PFAM secretion protein HlyD family protein
AM403_RS08965	COG3275	phosphorelay sensor kinase activity
AM403_RS08995	COG2271	Major facilitator Superfamily
AM403_RS09000	COG0251	oxidation-reduction process
AM403_RS09010	COG2964	Protein conserved in bacteria
AM403_RS09015	COG0513	Belongs to the DEAD box helicase family
AM403_RS09025	COG1185	polyribonucleotide nucleotidyltransferase activity
AM403_RS09030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM403_RS09035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM403_RS09040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM403_RS09045	COG3064	Membrane
AM403_RS09045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM403_RS09050	COG0195	Participates in both transcription termination and antitermination
AM403_RS09055	COG0779	Required for maturation of 30S ribosomal subunits
AM403_RS09070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM403_RS09075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM403_RS09080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM403_RS09085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM403_RS09090	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM403_RS09095	COG1534	Rna-binding protein
AM403_RS09105	COG2027	D-alanyl-D-alanine carboxypeptidase
AM403_RS09110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM403_RS09115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM403_RS09120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM403_RS09125	COG0142	geranyltranstransferase activity
AM403_RS09140	COG3423	Transcriptional regulator
AM403_RS09145	COG0039	L-malate dehydrogenase activity
AM403_RS09150	COG1438	arginine binding
AM403_RS09155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM403_RS09160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM403_RS09165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM403_RS09185	COG2105	PFAM AIG2 family protein
AM403_RS09190	COG2911	Protein conserved in bacteria
AM403_RS09195	COG0729	surface antigen
AM403_RS09200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM403_RS09205	COG1253	flavin adenine dinucleotide binding
AM403_RS09215	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AM403_RS09225	COG0545	Peptidyl-prolyl cis-trans isomerase
AM403_RS09230	COG1012	belongs to the aldehyde dehydrogenase family
AM403_RS09240	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM403_RS09245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM403_RS09250	COG0254	rRNA binding
AM403_RS09255	COG3061	Opacity-associated protein A
AM403_RS09260	COG0359	binds to the 23S rRNA
AM403_RS09265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM403_RS09270	COG2965	DNA replication, synthesis of RNA primer
AM403_RS09275	COG0360	Binds together with S18 to 16S ribosomal RNA
AM403_RS09280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM403_RS09285	COG0557	exoribonuclease II activity
AM403_RS09290	COG1959	2 iron, 2 sulfur cluster binding
AM403_RS09295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM403_RS09300	COG0330	HflC and HflK could
AM403_RS09305	COG0330	HflC and HflK could
AM403_RS09310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM403_RS09315	COG1923	regulation of RNA biosynthetic process
AM403_RS09320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM403_RS09325	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM403_RS09330	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM403_RS09335	COG0802	atpase or kinase
AM403_RS09340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM403_RS09370	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM403_RS09375	COG1162	GTPase activity
AM403_RS09380	COG0688	phosphatidylethanolamine metabolic process
AM403_RS09385	COG1511	domain protein
AM403_RS09385	COG3264	Mechanosensitive ion channel
AM403_RS09395	COG3539	Fimbrial protein
AM403_RS09400	COG3121	Chaperone
AM403_RS09405	COG3188	usher protein
AM403_RS09415	COG0561	phosphatase activity
AM403_RS09420	COG2267	carboxylic ester hydrolase activity
AM403_RS09435	COG2050	protein possibly involved in aromatic compounds catabolism
AM403_RS09440	COG2962	Rard protein
AM403_RS09450	COG0210	DNA helicase
AM403_RS09455	COG1011	Hydrolase
AM403_RS09470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM403_RS09475	COG5567	small periplasmic lipoprotein
AM403_RS09480	COG1965	Belongs to the frataxin family
AM403_RS09490	COG0181	hydroxymethylbilane synthase activity
AM403_RS09500	COG2959	enzyme of heme biosynthesis
AM403_RS09505	COG3071	HemY protein
AM403_RS09535	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM403_RS09545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM403_RS09550	COG2244	polysaccharide biosynthetic process
AM403_RS09555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM403_RS09560	COG0456	acetyltransferase
AM403_RS09565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM403_RS09570	COG1088	dTDP-glucose 4,6-dehydratase activity
AM403_RS09575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM403_RS09580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM403_RS09590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM403_RS09595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM403_RS09600	COG3118	belongs to the thioredoxin family
AM403_RS09605	COG0513	Belongs to the DEAD box helicase family
AM403_RS09610	COG0248	Ppx GppA phosphatase
AM403_RS09615	COG0210	DNA helicase
AM403_RS09625	COG3041	Addiction module toxin RelE StbE family
AM403_RS09630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM403_RS09645	COG0129	dihydroxy-acid dehydratase activity
AM403_RS09655	COG3978	acetolactate synthase activity
AM403_RS09670	COG0606	chelatase, subunit chli
AM403_RS09675	COG3085	chromosome segregation
AM403_RS09680	COG0583	DNA-binding transcription factor activity
AM403_RS09715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM403_RS09720	COG4206	TonB-dependent receptor
AM403_RS09725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM403_RS09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM403_RS09750	COG0165	Argininosuccinate lyase
AM403_RS09755	COG0137	argininosuccinate synthase activity
AM403_RS09760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM403_RS09765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM403_RS09770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM403_RS09775	COG0028	Belongs to the TPP enzyme family
AM403_RS09795	COG0583	DNA-binding transcription factor activity
AM403_RS09800	COG0477	Major facilitator Superfamily
AM403_RS09810	COG1216	Glycosyl transferase, family 2
AM403_RS09815	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM403_RS09820	COG2862	Uncharacterized protein family, UPF0114
AM403_RS09825	COG0527	aspartate kinase activity
AM403_RS09825	COG0460	homoserine dehydrogenase
AM403_RS09830	COG0626	cystathionine gamma-synthase activity
AM403_RS09835	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AM403_RS09840	COG3550	peptidyl-serine autophosphorylation
AM403_RS09845	COG0254	rRNA binding
AM403_RS09850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM403_RS09855	COG1609	Transcriptional regulator
AM403_RS09860	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM403_RS09865	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM403_RS09870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM403_RS09875	COG1575	Belongs to the MenA family. Type 1 subfamily
AM403_RS09880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM403_RS09885	COG3074	FtsZ-dependent cytokinesis
AM403_RS09895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM403_RS09900	COG2814	Major facilitator Superfamily
AM403_RS09905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM403_RS09910	COG3152	Membrane
AM403_RS09920	COG0149	triose-phosphate isomerase activity
AM403_RS09925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM403_RS09930	COG0205	6-phosphofructokinase activity
AM403_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS09940	COG0438	transferase activity, transferring glycosyl groups
AM403_RS10080	COG4695	Portal protein
AM403_RS10160	COG3678	ATP-independent chaperone mediated protein folding
AM403_RS10165	COG0745	RESPONSE REGULATOR receiver
AM403_RS10170	COG2205	protein histidine kinase activity
AM403_RS10195	COG0438	transferase activity, transferring glycosyl groups
AM403_RS10210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM403_RS10220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM403_RS10225	COG1216	Glycosyl transferase, family 2
AM403_RS10230	COG1045	serine acetyltransferase
AM403_RS10235	COG1045	serine acetyltransferase
AM403_RS10245	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AM403_RS10250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM403_RS10260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM403_RS10265	COG4942	peptidase
AM403_RS10270	COG2861	carbohydrate metabolic process
AM403_RS10275	COG1063	alcohol dehydrogenase
AM403_RS10280	COG0156	8-amino-7-oxononanoate synthase activity
AM403_RS10285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM403_RS10295	COG0859	PFAM glycosyl transferase family 9
AM403_RS10310	COG0438	transferase activity, transferring glycosyl groups
AM403_RS10315	COG0859	PFAM glycosyl transferase family 9
AM403_RS10320	COG0438	transferase activity, transferring glycosyl groups
AM403_RS10325	COG0438	transferase activity, transferring glycosyl groups
AM403_RS10330	COG0859	PFAM glycosyl transferase family 9
AM403_RS10335	COG1519	Transferase
AM403_RS10345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM403_RS10350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM403_RS10365	COG0297	glycogen (starch) synthase activity
AM403_RS10375	COG0438	transferase activity, transferring glycosyl groups
AM403_RS10380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM403_RS10385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM403_RS10395	COG2003	Belongs to the UPF0758 family
AM403_RS10400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM403_RS10405	COG0756	dUTP diphosphatase activity
AM403_RS10410	COG1309	transcriptional regulator
AM403_RS10415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM403_RS10420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM403_RS10425	COG1561	YicC-like family, N-terminal region
AM403_RS10445	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM403_RS10450	COG4106	trans-aconitate 2-methyltransferase activity
AM403_RS10455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM403_RS10460	COG0187	DNA topoisomerase II activity
AM403_RS10465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM403_RS10475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM403_RS10480	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM403_RS10485	COG0594	ribonuclease P activity
AM403_RS10490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM403_RS10495	COG0706	membrane insertase activity
AM403_RS10500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM403_RS10510	COG3550	peptidyl-serine autophosphorylation
AM403_RS10550	COG0583	DNA-binding transcription factor activity
AM403_RS10555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM403_RS10570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM403_RS10575	COG3383	formate dehydrogenase (NAD+) activity
AM403_RS10575	COG0243	molybdopterin cofactor binding
AM403_RS10580	COG0243	molybdopterin cofactor binding
AM403_RS10580	COG3383	formate dehydrogenase (NAD+) activity
AM403_RS10585	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS10590	COG2864	formate dehydrogenase
AM403_RS10595	COG3058	Necessary for formate dehydrogenase activity
AM403_RS10600	COG1921	L-seryl-tRNASec selenium transferase activity
AM403_RS10605	COG3276	selenocysteine insertion sequence binding
AM403_RS10610	COG1368	sulfuric ester hydrolase activity
AM403_RS10615	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AM403_RS10620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM403_RS10625	COG3706	GGDEF domain
AM403_RS10635	COG0457	Tetratricopeptide repeat
AM403_RS10645	COG1215	transferase activity, transferring glycosyl groups
AM403_RS10655	COG1940	carbohydrate kinase activity
AM403_RS10665	COG3111	PFAM Bacterial OB fold (BOF) protein
AM403_RS10690	COG3188	usher protein
AM403_RS10725	COG1288	antiporter activity
AM403_RS10735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM403_RS10750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM403_RS10755	COG1840	ABC-type Fe3 transport system, periplasmic component
AM403_RS10760	COG1178	ABC-type Fe3 transport system permease component
AM403_RS10765	COG3842	ATPase activity
AM403_RS10850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM403_RS10855	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM403_RS10860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM403_RS10865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM403_RS10870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM403_RS10875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM403_RS10880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM403_RS10885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM403_RS10895	COG0356	it plays a direct role in the translocation of protons across the membrane
AM403_RS10900	COG3312	ion transport
AM403_RS10905	COG0357	Ribosomal RNA small subunit methyltransferase G
AM403_RS10910	COG0445	tRNA wobble uridine modification
AM403_RS10915	COG0716	FMN binding
AM403_RS10920	COG1522	sequence-specific DNA binding
AM403_RS10925	COG2502	aspartate--ammonia ligase
AM403_RS10930	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AM403_RS10935	COG0714	Associated with various cellular activities
AM403_RS10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM403_RS10945	COG0477	Major facilitator Superfamily
AM403_RS10950	COG2186	Transcriptional regulator
AM403_RS10985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM403_RS10995	COG1072	(Pantothenic acid kinase))
AM403_RS11040	COG0051	transcription antitermination factor activity, RNA binding
AM403_RS11045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM403_RS11050	COG0088	Forms part of the polypeptide exit tunnel
AM403_RS11055	COG0089	rRNA binding
AM403_RS11060	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM403_RS11065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM403_RS11070	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM403_RS11080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM403_RS11085	COG0255	Belongs to the universal ribosomal protein uL29 family
AM403_RS11090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM403_RS11095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM403_RS11100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM403_RS11105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM403_RS11110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM403_RS11115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM403_RS11120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM403_RS11125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM403_RS11130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM403_RS11135	COG1841	ribosomal large subunit assembly
AM403_RS11140	COG0200	Binds to the 23S rRNA
AM403_RS11145	COG0201	protein transport
AM403_RS11150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM403_RS11155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM403_RS11165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM403_RS11175	COG0203	ribosomal protein L17
AM403_RS11180	COG0789	Transcriptional regulator
AM403_RS11185	COG3036	rescue of stalled ribosome
AM403_RS11190	COG1970	mechanosensitive ion channel activity
AM403_RS11195	COG0569	domain protein
AM403_RS11200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM403_RS11200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM403_RS11205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM403_RS11210	COG0242	peptide deformylase activity
AM403_RS11215	COG0758	DNA mediated transformation
AM403_RS11220	COG0551	DNA topoisomerase type I activity
AM403_RS11225	COG0009	L-threonylcarbamoyladenylate synthase
AM403_RS11230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM403_RS11240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM403_RS11270	COG0247	lactate metabolic process
AM403_RS11275	COG1139	Iron-sulfur cluster binding protein
AM403_RS11280	COG1556	Lactate utilization protein
AM403_RS11285	COG2194	sulfuric ester hydrolase activity
AM403_RS11290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM403_RS11295	COG3162	membrane
AM403_RS11300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM403_RS11305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM403_RS11310	COG2258	MOSC domain
AM403_RS11320	COG0675	Transposase, IS605 OrfB family
AM403_RS11325	COG0180	Tryptophanyl-tRNA synthetase
AM403_RS11330	COG0546	phosphoglycolate phosphatase activity
AM403_RS11335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM403_RS11350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM403_RS11355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM403_RS11360	COG4796	Type ii and iii secretion system protein
AM403_RS11380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM403_RS11390	COG0494	nUDIX hydrolase
AM403_RS11400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM403_RS11405	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM403_RS11410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM403_RS11415	COG1741	Belongs to the pirin family
AM403_RS11430	COG2081	HI0933 family
AM403_RS11435	COG0306	phosphate transporter
AM403_RS11445	COG0589	response to stress
AM403_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS11460	COG0742	ribosomal rna small subunit methyltransferase
AM403_RS11500	COG3188	usher protein
AM403_RS11540	COG3501	Rhs element vgr protein
AM403_RS11555	COG3122	Protein conserved in bacteria
AM403_RS11560	COG0564	pseudouridine synthase activity
AM403_RS11565	COG1278	Cold shock
AM403_RS11570	COG1737	Transcriptional regulator
AM403_RS11575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS11575	COG1263	PTS System
AM403_RS11580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM403_RS11585	COG0733	neurotransmitter:sodium symporter activity
AM403_RS11595	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AM403_RS11605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM403_RS11610	COG2731	YhcH YjgK YiaL family protein
AM403_RS11615	COG1737	Transcriptional regulator
AM403_RS11630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM403_RS11630	COG2755	lipolytic protein G-D-S-L family
AM403_RS11635	COG1285	pathogenesis
AM403_RS11640	COG2211	Major facilitator Superfamily
AM403_RS11650	COG1609	Transcriptional regulator
AM403_RS11655	COG3302	dmso reductase anchor subunit
AM403_RS11660	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS11665	COG0243	molybdopterin cofactor binding
AM403_RS11685	COG4604	ABC transporter, ATP-binding protein
AM403_RS11690	COG4605	iron ion homeostasis
AM403_RS11695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM403_RS11700	COG4607	ABC-type enterochelin transport system periplasmic component
AM403_RS11705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM403_RS11710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AM403_RS11715	COG1447	Phosphotransferase system cellobiose-specific component IIA
AM403_RS11720	COG1917	Cupin 2, conserved barrel domain protein
AM403_RS11720	COG2169	Transcriptional regulator
AM403_RS11725	COG1486	melibiose metabolic process
AM403_RS11730	COG3394	polysaccharide catabolic process
AM403_RS11745	COG2226	methyltransferase
AM403_RS11745	COG1073	alpha beta
AM403_RS11750	COG0747	negative chemotaxis
AM403_RS11755	COG0601	transmembrane transport
AM403_RS11770	COG1124	(ABC) transporter
AM403_RS11790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM403_RS11830	COG3189	MarR family transcriptional regulator
AM403_RS11835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM403_RS11840	COG1349	DNA-binding transcription factor activity
AM403_RS11845	COG0705	Rhomboid family
AM403_RS11850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AM403_RS11855	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM403_RS11855	COG0316	Belongs to the HesB IscA family
AM403_RS11860	COG1040	competence protein
AM403_RS11865	COG2267	carboxylic ester hydrolase activity
AM403_RS11880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM403_RS11885	COG1918	ferrous iron import across plasma membrane
AM403_RS11905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM403_RS11910	COG2252	PERMEase
AM403_RS11920	COG0736	holo-[acyl-carrier-protein] synthase activity
AM403_RS11925	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS11930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM403_RS11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM403_RS11940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM403_RS11945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM403_RS11960	COG1136	(ABC) transporter
AM403_RS11985	COG0765	amino acid transport
AM403_RS11990	COG0765	amino acid transport
AM403_RS11995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM403_RS12000	COG0704	Plays a role in the regulation of phosphate uptake
AM403_RS12010	COG0581	inorganic phosphate transmembrane transporter activity
AM403_RS12015	COG0573	inorganic phosphate transmembrane transporter activity
AM403_RS12020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM403_RS12035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM403_RS12040	COG2183	response to ionizing radiation
AM403_RS12080	COG1217	gtp-binding protein TYPA
AM403_RS12100	COG3550	peptidyl-serine autophosphorylation
AM403_RS12105	COG1011	Hydrolase
AM403_RS12110	COG1490	D-aminoacyl-tRNA deacylase activity
AM403_RS12115	COG0456	acetyltransferase
AM403_RS12120	COG1187	pseudouridine synthase activity
AM403_RS12130	COG2982	Protein involved in outer membrane biogenesis
AM403_RS12135	COG2233	PERMEase
AM403_RS12140	COG0786	glutamate:sodium symporter activity
AM403_RS12145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM403_RS12150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM403_RS12155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM403_RS12160	COG1758	RNA polymerase activity
AM403_RS12165	COG0194	GDP metabolic process
AM403_RS12170	COG2860	membrane
AM403_RS12175	COG0823	Involved in the tonB-independent uptake of proteins
AM403_RS12200	COG0751	glycine-tRNA ligase activity
AM403_RS12205	COG0752	glycyl-tRNA synthetase alpha subunit
AM403_RS12210	COG2818	Glycosylase
AM403_RS12215	COG3977	Valine--pyruvate aminotransferase
AM403_RS12220	COG2985	domain, Protein
AM403_RS12220	COG0569	domain protein
AM403_RS12225	COG5645	(Lipo)protein
AM403_RS12240	COG2831	hemolysin activation secretion protein
AM403_RS12245	COG0747	negative chemotaxis
AM403_RS12250	COG0601	transmembrane transport
AM403_RS12255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM403_RS12260	COG0444	Belongs to the ABC transporter superfamily
AM403_RS12265	COG4608	Belongs to the ABC transporter superfamily
AM403_RS12270	COG3210	domain, Protein
AM403_RS12275	COG2200	EAL domain
AM403_RS12275	COG2199	diguanylate cyclase activity
AM403_RS12285	COG1942	4-Oxalocrotonate Tautomerase
AM403_RS12290	COG1295	ribonuclease BN
AM403_RS12300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM403_RS12305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM403_RS12320	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM403_RS12325	COG0746	molybdenum cofactor guanylyltransferase activity
AM403_RS12330	COG3084	Protein conserved in bacteria
AM403_RS12335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM403_RS12340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM403_RS12350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM403_RS12350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM403_RS12355	COG0242	peptide deformylase activity
AM403_RS12365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM403_RS12375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM403_RS12380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM403_RS12385	COG1765	OsmC-like protein
AM403_RS12390	COG3954	Phosphoribulokinase
AM403_RS12395	COG3089	Belongs to the UPF0270 family
AM403_RS12400	COG0429	hydrolase of the alpha beta-hydrolase fold
AM403_RS12415	COG0840	transmembrane signaling receptor activity
AM403_RS12420	COG0840	transmembrane signaling receptor activity
AM403_RS12425	COG0840	transmembrane signaling receptor activity
AM403_RS12430	COG0488	(ABC) transporter
AM403_RS12435	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM403_RS12445	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM403_RS12450	COG1047	Peptidyl-prolyl cis-trans
AM403_RS12455	COG2900	Belongs to the SlyX family
AM403_RS12460	COG0545	Peptidyl-prolyl cis-trans isomerase
AM403_RS12470	COG2964	Protein conserved in bacteria
AM403_RS12475	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM403_RS12480	COG2923	Belongs to the DsrF TusC family
AM403_RS12490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM403_RS12495	COG0049	tRNA binding
AM403_RS12500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM403_RS12515	COG0250	Participates in transcription elongation, termination and antitermination
AM403_RS12520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM403_RS12525	COG0081	regulation of translation
AM403_RS12530	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM403_RS12535	COG0222	ribosome binding
AM403_RS12540	COG0085	RNA polymerase activity
AM403_RS12545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM403_RS12550	COG5464	transposase or invertase
AM403_RS12560	COG2022	thiamine diphosphate biosynthetic process
AM403_RS12565	COG2104	thiamine diphosphate biosynthetic process
AM403_RS12570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM403_RS12575	COG0352	thiamine-phosphate diphosphorylase activity
AM403_RS12580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM403_RS12590	COG2816	NAD+ diphosphatase activity
AM403_RS12595	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM403_RS12600	COG1515	deoxyribonuclease V activity
AM403_RS12605	COG3068	Protein conserved in bacteria
AM403_RS12620	COG0151	Belongs to the GarS family
AM403_RS12625	COG0138	bifunctional purine biosynthesis protein purh
AM403_RS12655	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AM403_RS12665	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM403_RS12670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM403_RS12675	COG2224	Isocitrate lyase
AM403_RS12685	COG0800	Aldolase
AM403_RS12690	COG0129	dihydroxy-acid dehydratase activity
AM403_RS12700	COG1410	methionine synthase
AM403_RS12700	COG0646	methionine synthase
AM403_RS12715	COG0527	aspartate kinase activity
AM403_RS12720	COG0166	Belongs to the GPI family
AM403_RS12725	COG3161	chorismate lyase activity
AM403_RS12730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM403_RS12735	COG2937	Belongs to the GPAT DAPAT family
AM403_RS12740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM403_RS12745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM403_RS12750	COG0735	belongs to the Fur family
AM403_RS12760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM403_RS12765	COG0814	amino acid
AM403_RS12775	COG1448	Aminotransferase
AM403_RS12795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM403_RS12820	COG1177	transmembrane transport
AM403_RS12840	COG3539	Fimbrial protein
AM403_RS12850	COG4974	Belongs to the 'phage' integrase family
AM403_RS12905	COG4695	Portal protein
AM403_RS13005	COG5301	cellulose 1,4-beta-cellobiosidase activity
AM403_RS13035	COG3188	usher protein
AM403_RS13055	COG2873	o-acetylhomoserine
AM403_RS13090	COG1454	alcohol dehydrogenase
AM403_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
AM403_RS13095	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM403_RS13105	COG1882	Formate acetyltransferase
AM403_RS13110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM403_RS13120	COG4869	propanediol catabolic process
AM403_RS13145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM403_RS13160	COG0789	Transcriptional regulator
AM403_RS13200	COG2207	Transcriptional regulator
AM403_RS13245	COG4790	Type iii secretion
AM403_RS13290	COG0157	Belongs to the NadC ModD family
AM403_RS13295	COG0500	methyltransferase
AM403_RS13300	COG1120	ATPase activity
AM403_RS13305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM403_RS13310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM403_RS13315	COG1609	Transcriptional regulator
AM403_RS13320	COG3265	gluconokinase activity
AM403_RS13325	COG2610	gluconate transmembrane transporter activity
AM403_RS13350	COG2992	FlgJ-related protein
AM403_RS13370	COG2137	regulation of response to DNA damage stimulus
AM403_RS13375	COG3397	chitin binding
AM403_RS13395	COG1024	Enoyl-CoA hydratase
AM403_RS13400	COG0318	PFAM AMP-dependent synthetase and ligase
AM403_RS13405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM403_RS13410	COG1960	acyl-CoA dehydrogenase activity
AM403_RS13430	COG0644	oxidoreductase
AM403_RS13435	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM403_RS13440	COG2271	Major facilitator Superfamily
AM403_RS13445	COG0318	PFAM AMP-dependent synthetase and ligase
AM403_RS13455	COG1924	4 iron, 4 sulfur cluster binding
AM403_RS13470	COG2610	gluconate transmembrane transporter activity
AM403_RS13475	COG1960	acyl-CoA dehydrogenase activity
AM403_RS13480	COG2086	electron transfer activity
AM403_RS13485	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM403_RS13490	COG0644	oxidoreductase
AM403_RS13495	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM403_RS13500	COG4977	sequence-specific DNA binding
AM403_RS13505	COG2255	four-way junction helicase activity
AM403_RS13520	COG1704	LemA family
AM403_RS13525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM403_RS13545	COG0305	Participates in initiation and elongation during chromosome replication
AM403_RS13625	COG1982	Orn Lys Arg decarboxylase major
AM403_RS13645	COG3059	membrane
AM403_RS13655	COG2801	Transposase and inactivated derivatives
AM403_RS13715	COG2375	cellular response to nickel ion
AM403_RS13715	COG1132	(ABC) transporter
AM403_RS13735	COG3433	isochorismatase activity
AM403_RS13735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM403_RS13735	COG2226	methyltransferase
AM403_RS13745	COG2814	Major facilitator Superfamily
AM403_RS13750	COG4771	TonB-dependent receptor
AM403_RS13895	COG0210	DNA helicase
AM403_RS13980	COG1309	transcriptional regulator
AM403_RS13985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AM403_RS14000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM403_RS14005	COG0459	protein refolding
AM403_RS14020	COG0702	epimerase
AM403_RS14055	COG3188	usher protein
AM403_RS14075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM403_RS14080	COG0698	ribose 5-phosphate isomerase
AM403_RS14085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM403_RS14090	COG0651	ATP synthesis coupled electron transport
AM403_RS14095	COG0650	Formate hydrogenlyase subunit 4
AM403_RS14100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM403_RS14105	COG4237	Hydrogenase 4 membrane
AM403_RS14110	COG0651	ATP synthesis coupled electron transport
AM403_RS14115	COG3261	NADH dehydrogenase
AM403_RS14115	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AM403_RS14120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM403_RS14125	COG3260	NADH ubiquinone oxidoreductase 20
AM403_RS14135	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AM403_RS14140	COG1216	Glycosyl transferase, family 2
AM403_RS14155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM403_RS14175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM403_RS14180	COG1328	CTP reductase activity
AM403_RS14185	COG3726	membrane protein affecting hemolysin expression
AM403_RS14190	COG0560	Phosphoserine phosphatase
AM403_RS14210	COG2382	esterase
AM403_RS14220	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM403_RS14235	COG2813	Specifically methylates the guanine in position
AM403_RS14255	COG1401	restriction endodeoxyribonuclease activity
AM403_RS14270	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM403_RS14280	COG4667	esterase of the alpha-beta hydrolase superfamily
AM403_RS14285	COG0084	hydrolase, TatD family'
AM403_RS14290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AM403_RS14295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM403_RS14300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AM403_RS14305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM403_RS14310	COG0813	purine-nucleoside phosphorylase activity
AM403_RS14315	COG2851	Citrate transporter
AM403_RS14325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM403_RS14330	COG0469	pyruvate kinase activity
AM403_RS14335	COG2271	Major facilitator Superfamily
AM403_RS14345	COG4191	Histidine kinase
AM403_RS14355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM403_RS14355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM403_RS14355	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AM403_RS14360	COG1461	Dihydroxyacetone kinase
AM403_RS14365	COG2376	Dihydroxyacetone kinase
AM403_RS14420	COG1358	cellular component organization or biogenesis
AM403_RS14470	COG0840	transmembrane signaling receptor activity
AM403_RS14475	COG0840	transmembrane signaling receptor activity
AM403_RS14480	COG0583	DNA-binding transcription factor activity
AM403_RS14485	COG0243	molybdopterin cofactor binding
AM403_RS14490	COG1271	oxidase subunit
AM403_RS14495	COG1294	oxidase, subunit
AM403_RS14505	COG3781	membrane
AM403_RS14525	COG0358	DNA primase activity
AM403_RS14530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM403_RS14540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM403_RS14545	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AM403_RS14565	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM403_RS14570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM403_RS14575	COG0617	tRNA 3'-terminal CCA addition
AM403_RS14580	COG4991	sh3 domain protein
AM403_RS14585	COG3025	triphosphatase activity
AM403_RS14590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM403_RS14595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AM403_RS14595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AM403_RS14605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM403_RS14610	COG3384	dioxygenase
AM403_RS14615	COG0754	glutathionylspermidine amidase activity
AM403_RS14620	COG5463	Belongs to the UPF0441 family
AM403_RS14625	COG1538	Outer membrane efflux protein
AM403_RS14630	COG0494	nUDIX hydrolase
AM403_RS14635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM403_RS14640	COG3150	esterase
AM403_RS14645	COG0187	DNA topoisomerase II activity
AM403_RS14650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM403_RS14655	COG0204	Acyl-transferase
AM403_RS14660	COG2132	Multicopper oxidase
AM403_RS14680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM403_RS14685	COG2967	ApaG domain
AM403_RS14690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM403_RS14695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM403_RS14700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM403_RS14705	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM403_RS14710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM403_RS14715	COG0564	pseudouridine synthase activity
AM403_RS14720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM403_RS14725	COG0417	DNA replication proofreading
AM403_RS14735	COG3311	Transcriptional regulator
AM403_RS14740	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AM403_RS14745	COG1178	ABC-type Fe3 transport system permease component
AM403_RS14750	COG4143	(ABC) transporter
AM403_RS14755	COG0494	nUDIX hydrolase
AM403_RS14765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM403_RS14770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM403_RS14800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM403_RS14805	COG1025	Belongs to the peptidase M16 family
AM403_RS14810	COG1074	ATP-dependent DNA helicase activity
AM403_RS14815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM403_RS14820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM403_RS14820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM403_RS14825	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM403_RS14845	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM403_RS14850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM403_RS14855	COG2166	iron-sulfur cluster assembly
AM403_RS14860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM403_RS14865	COG0583	DNA-binding transcription factor activity
AM403_RS14870	COG2363	Small membrane protein
AM403_RS14875	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AM403_RS14880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM403_RS14885	COG1611	Belongs to the LOG family
AM403_RS14890	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM403_RS14890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM403_RS14900	COG3098	single-species biofilm formation
AM403_RS14910	COG1263	PTS System
AM403_RS14910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS14920	COG0716	FMN binding
AM403_RS14930	COG2171	N-acyltransferase activity
AM403_RS14935	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AM403_RS14945	COG0052	Belongs to the universal ribosomal protein uS2 family
AM403_RS14950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM403_RS14955	COG0528	UMP kinase activity
AM403_RS14960	COG0233	cytoplasmic translational termination
AM403_RS14965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM403_RS14970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM403_RS14975	COG0575	Belongs to the CDS family
AM403_RS14995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM403_RS15000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM403_RS15005	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM403_RS15010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM403_RS15015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM403_RS15025	COG0825	malonyl-CoA metabolic process
AM403_RS15035	COG0037	tRNA processing
AM403_RS15040	COG4568	rho-dependent transcription termination
AM403_RS15045	COG3015	lipoprotein NlpE involved in copper resistance
AM403_RS15050	COG0442	prolyl-tRNA aminoacylation
AM403_RS15055	COG1720	tRNA m6t6A37 methyltransferase activity
AM403_RS15065	COG1464	Belongs to the NlpA lipoprotein family
AM403_RS15070	COG2011	ABC-type metal ion transport system permease component
AM403_RS15075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM403_RS15080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AM403_RS15135	COG0602	queuosine metabolic process
AM403_RS15140	COG0720	synthase
AM403_RS15150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM403_RS15155	COG0175	sulfate reduction
AM403_RS15160	COG1648	precorrin-2 dehydrogenase activity
AM403_RS15160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM403_RS15165	COG0175	sulfate reduction
AM403_RS15170	COG2895	sulfate adenylyltransferase (ATP) activity
AM403_RS15185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM403_RS15190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM403_RS15195	COG0585	pseudouridine synthase activity
AM403_RS15200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM403_RS15205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM403_RS15210	COG4942	peptidase
AM403_RS15210	COG1388	LysM domain
AM403_RS15220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM403_RS15230	COG3711	transcriptional antiterminator
AM403_RS15235	COG2190	(PTS) system
AM403_RS15235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS15235	COG1263	PTS System
AM403_RS15240	COG0613	PHP domain protein
AM403_RS15310	COG3539	Fimbrial protein
AM403_RS15335	COG0471	metal ion transport
AM403_RS15350	COG1335	isochorismatase
AM403_RS15355	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM403_RS15360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM403_RS15370	COG0549	Belongs to the carbamate kinase family
AM403_RS15380	COG0583	DNA-binding transcription factor activity
AM403_RS15390	COG4589	Belongs to the CDS family
AM403_RS15405	COG4566	intracellular signal transduction
AM403_RS15425	COG2962	Rard protein
AM403_RS15430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM403_RS15435	COG0326	Molecular chaperone. Has ATPase activity
AM403_RS15440	COG0563	adenylate kinase activity
AM403_RS15445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM403_RS15450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AM403_RS15455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM403_RS15460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM403_RS15460	COG4651	solute:proton antiporter activity
AM403_RS15470	COG0675	Transposase, IS605 OrfB family
AM403_RS15475	COG0737	Belongs to the 5'-nucleotidase family
AM403_RS15485	COG3735	TraB family
AM403_RS15500	COG0789	Transcriptional regulator
AM403_RS15510	COG0330	HflC and HflK could
AM403_RS15515	COG3118	belongs to the thioredoxin family
AM403_RS15520	COG0300	oxidoreductase activity
AM403_RS15525	COG2755	lipolytic protein G-D-S-L family
AM403_RS15530	COG4181	ATPase activity
AM403_RS15535	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM403_RS15540	COG0668	transmembrane transport
AM403_RS15550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM403_RS15555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM403_RS15560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM403_RS15565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM403_RS15570	COG0215	cysteine-tRNA ligase activity
AM403_RS15575	COG1105	Belongs to the carbohydrate kinase PfkB family
AM403_RS15580	COG2501	S4 domain
AM403_RS15585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM403_RS15700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM403_RS15745	COG1802	Transcriptional regulator
AM403_RS15745	COG4626	Terminase
AM403_RS15750	COG4695	Portal protein
AM403_RS15755	COG0740	serine-type endopeptidase activity
AM403_RS15865	COG0582	viral genome integration into host DNA
AM403_RS15870	COG0582	viral genome integration into host DNA
AM403_RS15920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM403_RS15930	COG0640	Transcriptional regulator
AM403_RS15935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AM403_RS15940	COG0384	phenazine biosynthesis protein PhzF
AM403_RS15960	COG0800	Aldolase
AM403_RS15965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM403_RS15980	COG3119	arylsulfatase activity
AM403_RS15985	COG0641	radical SAM
AM403_RS15990	COG1349	DNA-binding transcription factor activity
AM403_RS16000	COG2222	sugar isomerase
AM403_RS16005	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS16010	COG3715	PTS system
AM403_RS16015	COG3716	PTS system mannose fructose sorbose family IID component
AM403_RS16020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM403_RS16020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM403_RS16025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM403_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS16075	COG3119	arylsulfatase activity
AM403_RS16085	COG5295	Hep Hag repeat protein
AM403_RS16100	COG3038	cytochrome b561
AM403_RS16105	COG2353	YceI-like domain
AM403_RS16110	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AM403_RS16115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM403_RS16130	COG1115	amino acid carrier protein
AM403_RS16140	COG1151	hydroxylamine reductase activity
AM403_RS16145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM403_RS16155	COG2239	Acts as a magnesium transporter
AM403_RS16160	COG3091	SprT-like family
AM403_RS16165	COG0640	Transcriptional regulator
AM403_RS16185	COG1215	transferase activity, transferring glycosyl groups
AM403_RS16195	COG1192	Involved in chromosome partitioning
AM403_RS16205	COG2194	sulfuric ester hydrolase activity
AM403_RS16210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM403_RS16215	COG1166	arginine decarboxylase activity
AM403_RS16220	COG0010	Belongs to the arginase family
AM403_RS16230	COG3657	addiction module killer protein
AM403_RS16240	COG3066	DNA modification
AM403_RS16245	COG4533	DNA binding
AM403_RS16250	COG0066	3-isopropylmalate dehydratase activity
AM403_RS16255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM403_RS16260	COG0473	3-isopropylmalate dehydrogenase activity
AM403_RS16265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM403_RS16280	COG1022	Amp-dependent synthetase and ligase
AM403_RS16290	COG2001	Belongs to the MraZ family
AM403_RS16295	COG0275	rRNA processing
AM403_RS16305	COG0768	penicillin binding
AM403_RS16310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM403_RS16315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM403_RS16320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM403_RS16330	COG0772	Belongs to the SEDS family
AM403_RS16335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM403_RS16340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM403_RS16350	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM403_RS16355	COG0849	cell division
AM403_RS16365	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AM403_RS16380	COG0653	protein targeting
AM403_RS16385	COG0789	Transcriptional regulator
AM403_RS16410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM403_RS16415	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AM403_RS16420	COG0237	dephospho-CoA kinase activity
AM403_RS16430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM403_RS16435	COG4969	Belongs to the N-Me-Phe pilin family
AM403_RS16440	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM403_RS16445	COG2186	Transcriptional regulator
AM403_RS16450	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AM403_RS16455	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM403_RS16460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM403_RS16480	COG3112	Uncharacterised protein family (UPF0231)
AM403_RS16490	COG1279	arginine transmembrane transporter activity
AM403_RS16510	COG0583	DNA-binding transcription factor activity
AM403_RS16515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM403_RS16520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM403_RS16530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM403_RS16540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM403_RS16550	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AM403_RS16555	COG3079	Belongs to the UPF0149 family
AM403_RS16560	COG0006	proline dipeptidase activity
AM403_RS16565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM403_RS16570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM403_RS16575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM403_RS16580	COG0509	glycine decarboxylation via glycine cleavage system
AM403_RS16585	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM403_RS16585	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM403_RS16595	COG0354	folic acid binding
AM403_RS16600	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM403_RS16615	COG0716	FMN binding
AM403_RS16625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM403_RS16630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM403_RS16640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM403_RS16680	COG3539	Fimbrial protein
AM403_RS16685	COG3121	Chaperone
AM403_RS16690	COG3188	usher protein
AM403_RS16765	COG2841	Protein conserved in bacteria
AM403_RS16770	COG4574	serine-type endopeptidase inhibitor activity
AM403_RS16775	COG0589	response to stress
AM403_RS16780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM403_RS16790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM403_RS16795	COG1085	galactose-1-phosphate uridylyltransferase
AM403_RS16800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AM403_RS16805	COG2017	converts alpha-aldose to the beta-anomer
AM403_RS16810	COG1609	Transcriptional regulator
AM403_RS16820	COG4771	TonB-dependent receptor
AM403_RS16825	COG2819	hydrolase of the alpha beta superfamily
AM403_RS16835	COG3738	Protein conserved in bacteria
AM403_RS16840	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM403_RS16855	COG1556	Lactate utilization protein
AM403_RS16860	COG1139	Iron-sulfur cluster binding protein
AM403_RS16865	COG0247	lactate metabolic process
AM403_RS16870	COG1620	l-lactate permease
AM403_RS16875	COG2814	Major facilitator Superfamily
AM403_RS16880	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM403_RS16895	COG0579	oxidoreductase
AM403_RS16955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM403_RS16960	COG0732	type I restriction modification DNA specificity domain
AM403_RS16965	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM403_RS16980	COG0494	nUDIX hydrolase
AM403_RS16995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM403_RS17000	COG2867	negative regulation of translational initiation
AM403_RS17005	COG2914	Belongs to the UPF0125 (RnfH) family
AM403_RS17015	COG0497	DNA recombination
AM403_RS17020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM403_RS17025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM403_RS17030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM403_RS17040	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AM403_RS17045	COG0513	Belongs to the DEAD box helicase family
AM403_RS17050	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AM403_RS17055	COG1595	DNA-templated transcription, initiation
AM403_RS17060	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AM403_RS17065	COG3026	antisigma factor binding
AM403_RS17070	COG3086	response to oxidative stress
AM403_RS17075	COG0481	GTPase activity
AM403_RS17080	COG0681	Belongs to the peptidase S26 family
AM403_RS17085	COG0571	ribonuclease III activity
AM403_RS17090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM403_RS17095	COG1381	Involved in DNA repair and RecF pathway recombination
AM403_RS17100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM403_RS17105	COG0736	holo-[acyl-carrier-protein] synthase activity
AM403_RS17110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM403_RS17175	COG4626	Terminase
AM403_RS17175	COG1802	Transcriptional regulator
AM403_RS17180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM403_RS17185	COG0305	Participates in initiation and elongation during chromosome replication
AM403_RS17380	COG0438	transferase activity, transferring glycosyl groups
AM403_RS17395	COG3083	sulfuric ester hydrolase activity
AM403_RS17400	COG3082	Protein of unknown function (DUF1414)
AM403_RS17405	COG3081	Nucleoid-associated protein
AM403_RS17410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM403_RS17415	COG1061	Type III restriction enzyme res subunit
AM403_RS17420	COG1187	pseudouridine synthase activity
AM403_RS17425	COG2814	Major facilitator Superfamily
AM403_RS17435	COG0791	NLP P60 protein
AM403_RS17440	COG0671	phosphoesterase, PA-phosphatase related
AM403_RS17455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM403_RS17465	COG0494	nUDIX hydrolase
AM403_RS17470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AM403_RS17475	COG2855	membrane
AM403_RS17480	COG0583	DNA-binding transcription factor activity
AM403_RS17485	COG0833	amino acid
AM403_RS17495	COG4771	TonB-dependent receptor
AM403_RS17505	COG0531	amino acid
AM403_RS17515	COG3961	Belongs to the TPP enzyme family
AM403_RS17520	COG0583	DNA-binding transcription factor activity
AM403_RS17525	COG0277	FAD linked oxidase domain protein
AM403_RS17530	COG2925	Exonuclease
AM403_RS17535	COG2211	Major facilitator Superfamily
AM403_RS17540	COG2926	Belongs to the UPF0265 family
AM403_RS17545	COG1530	ribonuclease E activity
AM403_RS17550	COG0564	pseudouridine synthase activity
AM403_RS17560	COG0424	maF-like protein
AM403_RS17565	COG1399	metal-binding, possibly nucleic acid-binding protein
AM403_RS17570	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM403_RS17575	COG0416	fatty acid biosynthetic process
AM403_RS17580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM403_RS17595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM403_RS17600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM403_RS17605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM403_RS17610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM403_RS17615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM403_RS17620	COG0470	DNA polymerase III
AM403_RS17625	COG0084	hydrolase, TatD family'
AM403_RS17630	COG0537	adenosine 5'-monophosphoramidase activity
AM403_RS17635	COG5633	Lipoprotein
AM403_RS17640	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AM403_RS17650	COG1472	Belongs to the glycosyl hydrolase 3 family
AM403_RS17660	COG1252	NADH dehydrogenase
AM403_RS17665	COG3134	Outer membrane lipoprotein
AM403_RS17670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM403_RS17675	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM403_RS17685	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM403_RS17705	COG2850	peptidyl-arginine hydroxylation
AM403_RS17710	COG2205	protein histidine kinase activity
AM403_RS17715	COG0745	RESPONSE REGULATOR receiver
AM403_RS17720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM403_RS17725	COG2915	High frequency lysogenization protein hflD homolog
AM403_RS17730	COG0482	sulfurtransferase activity
AM403_RS17740	COG1187	pseudouridine synthase activity
AM403_RS17745	COG0538	isocitrate dehydrogenase activity
AM403_RS17750	COG0582	viral genome integration into host DNA
AM403_RS17760	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM403_RS17765	COG5532	Uncharacterized conserved protein (DUF2303)
AM403_RS17825	COG1403	HNH endonuclease
AM403_RS17850	COG3772	lysozyme
AM403_RS17885	COG1802	Transcriptional regulator
AM403_RS17885	COG4626	Terminase
AM403_RS17895	COG4695	Portal protein
AM403_RS18020	COG0538	isocitrate dehydrogenase activity
AM403_RS18060	COG1278	Cold shock
AM403_RS18065	COG0071	Belongs to the small heat shock protein (HSP20) family
AM403_RS18075	COG1733	regulation of RNA biosynthetic process
AM403_RS18080	COG0702	epimerase
AM403_RS18090	COG0572	uridine kinase
AM403_RS18110	COG1475	DNA binding
AM403_RS18115	COG3969	phosphoadenosine phosphosulfate
AM403_RS18120	COG0500	methyltransferase
AM403_RS18130	COG3272	Protein of unknown function (DUF1722)
AM403_RS18135	COG2841	Protein conserved in bacteria
AM403_RS18165	COG0024	Methionine aminopeptidase
AM403_RS18175	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AM403_RS18180	COG1598	PFAM Uncharacterised protein family UPF0150
AM403_RS18190	COG0675	Transposase, IS605 OrfB family
AM403_RS18195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AM403_RS18215	COG1528	Iron-storage protein
AM403_RS18220	COG2372	response to copper ion
AM403_RS18225	COG1276	copper resistance
AM403_RS18240	COG3008	intermembrane lipid transfer
AM403_RS18245	COG2995	paraquat-inducible protein a
AM403_RS18250	COG1956	GAF domain-containing protein
AM403_RS18255	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AM403_RS18275	COG0501	Belongs to the peptidase M48B family
AM403_RS18280	COG1823	symporter activity
AM403_RS18285	COG1988	membrane-bound metal-dependent
AM403_RS18290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM403_RS18300	COG3001	Fructosamine kinase
AM403_RS18305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM403_RS18310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM403_RS18315	COG1121	(ABC) transporter
AM403_RS18320	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM403_RS18340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM403_RS18350	COG3539	Fimbrial protein
AM403_RS18355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM403_RS18360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM403_RS18365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM403_RS18370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM403_RS18375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM403_RS18380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM403_RS18380	COG0072	phenylalanine-tRNA ligase activity
AM403_RS18385	COG0776	regulation of translation
AM403_RS18390	COG4139	cobalamin transport
AM403_RS18395	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AM403_RS18400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM403_RS18405	COG0463	Glycosyl transferase, family 2
AM403_RS18410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM403_RS18410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM403_RS18415	COG0726	polysaccharide deacetylase
AM403_RS18420	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM403_RS18425	COG2076	Multidrug Resistance protein
AM403_RS18430	COG2076	Multidrug Resistance protein
AM403_RS18435	COG0791	NLP P60 protein
AM403_RS18440	COG0095	Lipoate-protein ligase
AM403_RS18445	COG2207	Transcriptional regulator
AM403_RS18450	COG0579	oxidoreductase
AM403_RS18455	COG2186	Transcriptional regulator
AM403_RS18470	COG0586	Pfam SNARE associated Golgi protein
AM403_RS18535	COG3209	COG3209 Rhs family protein
AM403_RS18545	COG0012	GTP binding
AM403_RS18550	COG0193	aminoacyl-tRNA hydrolase activity
AM403_RS18560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM403_RS18565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM403_RS18570	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM403_RS18575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM403_RS18580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM403_RS18590	COG2912	Transglutaminase-like superfamily
AM403_RS18595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM403_RS18600	COG1242	4 iron, 4 sulfur cluster binding
AM403_RS18610	COG0659	secondary active sulfate transmembrane transporter activity
AM403_RS18620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM403_RS18635	COG3381	protein complex oligomerization
AM403_RS18645	COG0477	Major facilitator Superfamily
AM403_RS18650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM403_RS18655	COG0728	peptidoglycan biosynthetic process
AM403_RS18665	COG0018	arginyl-trna synthetase
AM403_RS18670	COG3102	Protein conserved in bacteria
AM403_RS18675	COG3142	Participates in the control of copper homeostasis
AM403_RS18685	COG0488	(ABC) transporter
AM403_RS18690	COG0500	methyltransferase
AM403_RS18695	COG2226	methyltransferase
AM403_RS18700	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM403_RS18705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM403_RS18710	COG0494	nUDIX hydrolase
AM403_RS18715	COG0217	transcriptional regulatory protein
AM403_RS18720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM403_RS18725	COG0632	four-way junction helicase activity
AM403_RS18730	COG2255	four-way junction helicase activity
AM403_RS18740	COG3501	Rhs element vgr protein
AM403_RS18750	COG3209	COG3209 Rhs family protein
AM403_RS18785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM403_RS18790	COG1121	(ABC) transporter
AM403_RS18795	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM403_RS18800	COG0739	heme binding
AM403_RS18805	COG1560	Kdo2-lipid A biosynthetic process
AM403_RS18810	COG0469	pyruvate kinase activity
AM403_RS18815	COG1737	Transcriptional regulator
AM403_RS18820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM403_RS18825	COG2076	Multidrug Resistance protein
AM403_RS18830	COG2076	Multidrug Resistance protein
AM403_RS18835	COG0702	epimerase
AM403_RS18840	COG0251	oxidation-reduction process
AM403_RS18845	COG1199	ATP-dependent helicase activity
AM403_RS18855	COG3065	identical protein binding
AM403_RS18860	COG0318	PFAM AMP-dependent synthetase and ligase
AM403_RS18865	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM403_RS18870	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM403_RS18875	COG2894	cell division
AM403_RS18880	COG0850	regulation of cytokinetic process
AM403_RS18885	COG3100	YcgL domain-containing protein
AM403_RS18890	COG2951	lytic endotransglycosylase activity
AM403_RS18895	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM403_RS18900	COG2983	Belongs to the UPF0260 family
AM403_RS18905	COG0390	transport system, permease component
AM403_RS18910	COG4619	ABC transporter
AM403_RS18920	COG2207	Transcriptional regulator
AM403_RS18920	COG3708	Transcriptional regulator
AM403_RS18935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM403_RS18940	COG2911	Protein conserved in bacteria
AM403_RS18950	COG3784	Protein of unknown function (DUF1318)
AM403_RS18975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM403_RS18990	COG1643	Atp-dependent helicase
AM403_RS19005	COG3188	usher protein
AM403_RS19020	COG0531	amino acid
AM403_RS19030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM403_RS19035	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM403_RS19040	COG0589	response to stress
AM403_RS19045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM403_RS19050	COG0243	molybdopterin cofactor binding
AM403_RS19055	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS19070	COG0604	alcohol dehydrogenase
AM403_RS19070	COG1028	Short-chain dehydrogenase reductase Sdr
AM403_RS19070	COG3321	synthase
AM403_RS19080	COG1695	Transcriptional regulator
AM403_RS19095	COG3634	alkyl hydroperoxide reductase activity
AM403_RS19125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM403_RS19130	COG4974	Belongs to the 'phage' integrase family
AM403_RS19140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM403_RS19145	COG0842	Transport permease protein
AM403_RS19145	COG1129	ABC transporter
AM403_RS19150	COG0842	Transport permease protein
AM403_RS19155	COG0745	RESPONSE REGULATOR receiver
AM403_RS19160	COG2205	protein histidine kinase activity
AM403_RS19165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AM403_RS19170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM403_RS19175	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM403_RS19180	COG0666	response to abiotic stimulus
AM403_RS19185	COG0590	tRNA wobble adenosine to inosine editing
AM403_RS19190	COG3381	protein complex oligomerization
AM403_RS19195	COG3302	dmso reductase anchor subunit
AM403_RS19200	COG0437	4 iron, 4 sulfur cluster binding
AM403_RS19205	COG0243	molybdopterin cofactor binding
AM403_RS19210	COG1349	DNA-binding transcription factor activity
AM403_RS19230	COG2376	Dihydroxyacetone kinase
AM403_RS19240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM403_RS19250	COG0251	oxidation-reduction process
AM403_RS19270	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AM403_RS19275	COG2169	Transcriptional regulator
AM403_RS19275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM403_RS19280	COG3097	Belongs to the UPF0267 family
AM403_RS19285	COG0488	(ABC) transporter
AM403_RS19290	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM403_RS19310	COG1464	Belongs to the NlpA lipoprotein family
AM403_RS19330	COG2814	Major facilitator Superfamily
AM403_RS19340	COG0583	DNA-binding transcription factor activity
AM403_RS19350	COG1309	transcriptional regulator
AM403_RS19360	COG0488	(ABC) transporter
AM403_RS19365	COG1671	Belongs to the UPF0178 family
AM403_RS19370	COG0402	S-adenosylhomocysteine deaminase activity
AM403_RS19380	COG2814	Major facilitator Superfamily
AM403_RS19385	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM403_RS19400	COG1289	transmembrane transporter activity
AM403_RS19405	COG1538	Outer membrane efflux protein
AM403_RS19415	COG0443	Heat shock 70 kDa protein
AM403_RS19435	COG1070	Carbohydrate kinase
AM403_RS19440	COG2115	Belongs to the xylose isomerase family
AM403_RS19445	COG1757	Na H antiporter
AM403_RS19450	COG0436	Aminotransferase
AM403_RS19455	COG2207	Transcriptional regulator
AM403_RS19455	COG1609	Transcriptional regulator
AM403_RS19460	COG4628	conserved protein (DUF2132)
AM403_RS19520	COG4221	oxidoreductase activity
AM403_RS19535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM403_RS19540	COG1940	carbohydrate kinase activity
AM403_RS19545	COG0583	DNA-binding transcription factor activity
AM403_RS19550	COG2814	Major facilitator Superfamily
AM403_RS19560	COG0114	fumarate hydratase activity
AM403_RS19565	COG5339	Protein conserved in bacteria
AM403_RS19575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM403_RS19580	COG0385	Bile acid
AM403_RS19585	COG0673	inositol 2-dehydrogenase activity
AM403_RS19595	COG4657	Part of a membrane complex involved in electron transport
AM403_RS19605	COG4656	Part of a membrane complex involved in electron transport
AM403_RS19615	COG4659	FMN binding
AM403_RS19625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM403_RS19630	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AM403_RS19635	COG0023	Translation Initiation Factor
AM403_RS19640	COG0284	orotidine-5'-phosphate decarboxylase activity
AM403_RS19645	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AM403_RS19650	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AM403_RS19655	COG0671	phosphoesterase, PA-phosphatase related
AM403_RS19660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM403_RS19665	COG1464	Belongs to the NlpA lipoprotein family
AM403_RS19675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM403_RS19685	COG0583	DNA-binding transcription factor activity
AM403_RS19745	COG5001	Diguanylate cyclase
AM403_RS19745	COG3300	MHYT domain
AM403_RS19845	COG4974	Belongs to the 'phage' integrase family
AM403_RS20000	COG0616	signal peptide processing
AM403_RS20120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM403_RS20180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM403_RS20240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM403_RS20330	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM403_RS20365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM403_RS20385	COG1192	Involved in chromosome partitioning
AM403_RS20465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM403_RS20555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM403_RS20580	COG5001	Diguanylate cyclase
AM403_RS20615	COG0714	Associated with various cellular activities
AM403_RS20625	COG0629	single-stranded DNA binding
AM403_RS20670	COG0633	Ferredoxin
AM403_RS20865	COG4227	nucleotidyltransferase activity
AM403_RS20900	COG1487	ribonuclease activity
AM403_RS20935	COG2948	multi-organism process
AM403_RS20945	COG3504	Conjugal transfer protein
AM403_RS20955	COG3701	Conjugal transfer protein
AM403_RS20975	COG3451	type IV secretory pathway VirB4
AM403_RS20985	COG3838	Conjugal transfer protein Trbc
AM403_RS20990	COG4962	Type ii secretion system protein e
AM403_RS21040	COG1192	Involved in chromosome partitioning
AM403_RS21160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone