locus-tag	class	description
HRD54_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HRD54_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HRD54_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HRD54_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD54_RS00025	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRD54_RS00030	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD54_RS00050	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HRD54_RS00155	ENOG4105DSJ	YicC domain protein
HRD54_RS00160	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HRD54_RS00165	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HRD54_RS00170	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HRD54_RS00175	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HRD54_RS00180	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HRD54_RS00185	ENOG4105W5Q	DNA repair protein (RadC
HRD54_RS00190	ENOG4105KDC	50s ribosomal protein l28
HRD54_RS00195	ENOG4105W0E	50S ribosomal protein L33
HRD54_RS00200	ENOG4105CPK	Glycosyl transferase (Group 1
HRD54_RS00210	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HRD54_RS00220	ENOG4108FRV	O-antigen ligase
HRD54_RS00225	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HRD54_RS00230	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HRD54_RS00240	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HRD54_RS00250	ENOG4107RJ7	Glycosyl transferase (Group 1
HRD54_RS00255	ENOG4105DKP	glycosyl transferase, family 9
HRD54_RS00270	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HRD54_RS00275	ENOG4105XA0	heptosyltransferase ii
HRD54_RS00280	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HRD54_RS00285	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRD54_RS00290	ENOG4105CPQ	Dehydrogenase
HRD54_RS00295	ENOG4105PXI	polysaccharide deacetylase
HRD54_RS00300	ENOG41063SB	peptidase
HRD54_RS00305	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HRD54_RS00315	ENOG4107YZP	Rhodanese domain protein
HRD54_RS00320	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HRD54_RS00330	ENOG4105D7W	serine acetyltransferase
HRD54_RS00335	ENOG4105D7W	serine acetyltransferase
HRD54_RS00340	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HRD54_RS00350	ENOG4105DMT	epimerase dehydratase
HRD54_RS00370	ENOG4107STW	synthase
HRD54_RS00410	ENOG4105E0F	Histidine kinase
HRD54_RS00415	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD54_RS00420	ENOG4105FMW	periplasmic
HRD54_RS00425	ENOG4107XU6	Glycosyl transferase (Group 1
HRD54_RS00430	ENOG4105CPK	Glycosyl transferase (Group 1
HRD54_RS00435	ENOG4105CHR	reductase
HRD54_RS00440	ENOG4105CTQ	phosphohexokinase
HRD54_RS00445	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HRD54_RS00450	ENOG4105CP7	Triose-phosphate isomerase
HRD54_RS00455	ENOG4105EBK	exported protein
HRD54_RS00460	ENOG4108VTS	Membrane
HRD54_RS00465	ENOG4105DP0	ferredoxin-NADP reductase
HRD54_RS00470	ENOG4105E5M	Multidrug resistance protein D
HRD54_RS00475	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HRD54_RS00480	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD54_RS00485	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HRD54_RS00495	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
HRD54_RS00500	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HRD54_RS00505	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HRD54_RS00510	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HRD54_RS00515	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HRD54_RS00520	ENOG41063M6	Cell Division Protein
HRD54_RS00525	ENOG4105ETE	Transcriptional regulator (LacI family
HRD54_RS00530	ENOG4105C25	Primosomal protein n'
HRD54_RS00535	ENOG41082DI	50s ribosomal protein l31
HRD54_RS00540	ENOG4105EUP	HipA domain protein
HRD54_RS00545	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HRD54_RS00550	ENOG4105C28	cystathionine
HRD54_RS00555	ENOG4105CFH	Aspartokinase
HRD54_RS00560	ENOG4108TEB	UPF0114 protein
HRD54_RS00570	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HRD54_RS00575	ENOG4105K64	Glycosyl transferase, family 2
HRD54_RS00580	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HRD54_RS00585	ENOG4105CSH	Transporter
HRD54_RS00590	ENOG4107R11	Transcriptional regulator
HRD54_RS00610	ENOG4105C7K	acetolactate synthase
HRD54_RS00615	ENOG4105CWC	Acetylornithine deacetylase
HRD54_RS00620	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HRD54_RS00625	ENOG4105CAS	nag kinase
HRD54_RS00630	ENOG4105CDH	Citrulline--aspartate ligase
HRD54_RS00635	ENOG4105CH7	arginosuccinase
HRD54_RS00640	ENOG4105C5Q	Transcriptional regulator
HRD54_RS00645	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HRD54_RS00655	ENOG4108Y73	Membrane
HRD54_RS00660	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HRD54_RS00665	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HRD54_RS00670	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HRD54_RS00705	ENOG4105D4A	Cell wall formation (By similarity)
HRD54_RS00710	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HRD54_RS00715	ENOG4105CS9	pantothenic acid kinase
HRD54_RS00740	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRD54_RS00760	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HRD54_RS00765	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HRD54_RS00770	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HRD54_RS00775	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HRD54_RS00780	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HRD54_RS00785	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HRD54_RS00795	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HRD54_RS00800	ENOG41083MP	50s ribosomal protein l29
HRD54_RS00805	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HRD54_RS00810	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HRD54_RS00815	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HRD54_RS00820	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HRD54_RS00825	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HRD54_RS00830	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HRD54_RS00835	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HRD54_RS00840	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HRD54_RS00845	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HRD54_RS00850	ENOG4105VPB	50S ribosomal protein L30
HRD54_RS00855	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HRD54_RS00860	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HRD54_RS00865	ENOG41067V7	50S ribosomal protein L36
HRD54_RS00870	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HRD54_RS00875	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HRD54_RS00880	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HRD54_RS00890	ENOG4108ZT0	50S ribosomal protein l17
HRD54_RS00895	ENOG4105W1Y	Transcriptional regulator
HRD54_RS00900	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HRD54_RS00905	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HRD54_RS00910	ENOG4105C1A	potassium transporter peripheral membrane
HRD54_RS00915	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HRD54_RS00920	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HRD54_RS00925	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HRD54_RS00930	ENOG4105C79	DNA protecting protein DprA
HRD54_RS00935	ENOG4108WI1	Dna topoisomerase
HRD54_RS00940	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRD54_RS00945	ENOG4105E2X	shikimate dehydrogenase
HRD54_RS00950	ENOG4105SG3	Protein of unknown function (DUF1488)
HRD54_RS00955	ENOG4108Z0R	Transferase
HRD54_RS00995	ENOG4105CVI	Transcriptional regulator
HRD54_RS01000	ENOG4108WFC	UPF0438 protein yifE
HRD54_RS01005	ENOG4105C0P	Mg chelatase subunit ChlI
HRD54_RS01020	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HRD54_RS01025	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HRD54_RS01030	ENOG4105C01	Dihydroxy-acid dehydratase
HRD54_RS01035	ENOG4105C7B	Threonine dehydratase
HRD54_RS01040	ENOG4105EMY	transcriptional regulator
HRD54_RS01045	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HRD54_RS01050	ENOG4105VXN	addiction module toxin, RelE StbE family
HRD54_RS01060	ENOG4105C4R	Atp-dependent dna helicase
HRD54_RS01065	ENOG4105C9X	ppx gppa phosphatase
HRD54_RS01070	ENOG4105C1J	atp-dependent rna helicase
HRD54_RS01080	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HRD54_RS01085	ENOG4105ESV	Glycosyl transferase, family 4
HRD54_RS01090	ENOG4105SFE	lipopolysaccharide biosynthesis protein
HRD54_RS01095	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HRD54_RS01100	ENOG4108IJ1	Dehydrogenase
HRD54_RS01105	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HRD54_RS01110	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HRD54_RS01115	ENOG4108WJ1	acetyltransferase
HRD54_RS01120	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD54_RS01125	ENOG4105EGZ	biosynthesis protein
HRD54_RS01130	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
HRD54_RS01135	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
HRD54_RS01140	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HRD54_RS01165	ENOG4108RS6	transposase
HRD54_RS01170	ENOG4105D7V	transposase
HRD54_RS01180	ENOG410601J	HemY protein
HRD54_RS01185	ENOG4105ECF	c-methyltransferase
HRD54_RS01195	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HRD54_RS01200	ENOG4107T0K	Adenylate cyclase
HRD54_RS01205	ENOG4105XQ6	frataxin-like protein
HRD54_RS01210	ENOG4105S7Z	(LipO)protein
HRD54_RS01215	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HRD54_RS01220	ENOG4105CT0	Protein of unknown function, DUF484
HRD54_RS01225	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD54_RS01230	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HRD54_RS01235	ENOG4105C4R	Atp-dependent dna helicase
HRD54_RS01245	ENOG4105FR1	rard protein
HRD54_RS01250	ENOG4108VUY	thioesterase Superfamily protein
HRD54_RS01255	ENOG4105HDD	phospholipase
HRD54_RS01260	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HRD54_RS01265	ENOG4108EUD	Lysophospholipase
HRD54_RS01270	ENOG4105DQF	Hydrolase
HRD54_RS01280	ENOG4105CW0	outer membrane usher protein
HRD54_RS01285	ENOG4108AF8	Chaperone
HRD54_RS01290	ENOG4108S54	Fimbrial protein
HRD54_RS01300	ENOG4105EGS	Mechanosensitive ion channel
HRD54_RS01305	ENOG4105DJ4	phosphatidylserine decarboxylase
HRD54_RS01310	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HRD54_RS01315	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HRD54_RS01345	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HRD54_RS01350	ENOG4105K8N	protein family UPF0079, ATPase
HRD54_RS01355	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRD54_RS01360	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HRD54_RS01365	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HRD54_RS01370	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HRD54_RS01375	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HRD54_RS01380	ENOG4107QJR	hflk protein
HRD54_RS01385	ENOG4105EPW	hflc protein
HRD54_RS01390	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HRD54_RS01395	ENOG4105KPV	Transcriptional regulator
HRD54_RS01400	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HRD54_RS01405	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HRD54_RS01410	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HRD54_RS01415	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HRD54_RS01420	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HRD54_RS01425	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HRD54_RS01430	ENOG4105FHY	Opacity-associated protein A
HRD54_RS01435	ENOG4105NRA	50s ribosomal protein l31 type b
HRD54_RS01440	ENOG4105YK5	50S ribosomal protein L36
HRD54_RS01445	ENOG4108MEK	Metal-binding protein YodA
HRD54_RS01450	ENOG4105C26	Dehydrogenase
HRD54_RS01455	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRD54_RS01460	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HRD54_RS01465	ENOG4108UUE	Transcriptional regulator
HRD54_RS01470	ENOG41061GZ	Protein of unknown function (DUF1107)
HRD54_RS01475	ENOG4105C37	(CBS) domain
HRD54_RS01480	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HRD54_RS01485	ENOG4105CFU	surface antigen
HRD54_RS01490	ENOG4105MA0	exported protein
HRD54_RS01495	ENOG4108ZHD	aig2 family
HRD54_RS01515	ENOG4105F0N	pyrophosphate phospho-hydrolase
HRD54_RS01520	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HRD54_RS01525	ENOG4105DFU	Cell wall formation (By similarity)
HRD54_RS01530	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HRD54_RS01535	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HRD54_RS01540	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD54_RS01555	ENOG4105EAH	synthase
HRD54_RS01560	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HRD54_RS01565	ENOG4105K46	50S ribosomal protein l27
HRD54_RS01570	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HRD54_RS01575	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HRD54_RS01580	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HRD54_RS01585	ENOG4105HBR	Rna-binding protein
HRD54_RS01590	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HRD54_RS01595	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HRD54_RS01600	ENOG4105EEI	dihydropteroate synthase
HRD54_RS01605	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HRD54_RS01610	ENOG4105NTZ	Preprotein translocase subunit SecG
HRD54_RS01625	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HRD54_RS01630	ENOG4105CHV	Transcription elongation factor NusA
HRD54_RS01635	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HRD54_RS01640	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HRD54_RS01645	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HRD54_RS01650	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HRD54_RS01655	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HRD54_RS01665	ENOG4105C1J	atp-dependent rna helicase
HRD54_RS01670	ENOG4105WWK	YheO domain protein
HRD54_RS01680	ENOG4105KME	endoribonuclease L-psp
HRD54_RS01685	ENOG4105R9B	Major Facilitator
HRD54_RS01710	ENOG4108NEV	two component transcriptional regulator, LytTR family
HRD54_RS01715	ENOG4108HRK	Histidine kinase
HRD54_RS01720	ENOG4105J12	Multidrug resistance protein mdtN
HRD54_RS01735	ENOG4108RQP	Major type 1 subunit fimbrin
HRD54_RS01740	ENOG4108NAE	Fimbrial chaperone protein
HRD54_RS01745	ENOG4105CW0	outer membrane usher protein
HRD54_RS01750	ENOG4108SQA	Fimbrial
HRD54_RS01755	ENOG4108T65	Fimbrial
HRD54_RS01790	ENOG4108YYD	acetyltransferase
HRD54_RS01795	ENOG41082IR	Excinuclease ABC C subunit domain protein
HRD54_RS01800	ENOG4105ZY9	UPF0379 protein ybiM
HRD54_RS01820	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HRD54_RS01825	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HRD54_RS01830	ENOG4105KME	endoribonuclease L-psp
HRD54_RS01835	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HRD54_RS01840	ENOG4105CXT	aspartate transcarbamylase
HRD54_RS01850	ENOG4105DBV	ornithine carbamoyltransferase
HRD54_RS01855	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HRD54_RS01860	ENOG4105EUB	pirin domain protein
HRD54_RS01865	ENOG4105VYH	
HRD54_RS01870	ENOG4108MJ3	acetyltransferase
HRD54_RS01875	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HRD54_RS01880	ENOG4105MYG	DNA polymerase iii, chi subunit
HRD54_RS01885	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HRD54_RS01890	ENOG4108M8S	permease YjgP YjgQ family protein
HRD54_RS01895	ENOG4108K5H	permease YjgP YjgQ family protein
HRD54_RS01900	ENOG4107R6D	beta-lactam binding protein AmpH
HRD54_RS01935	ENOG4108S2Y	peptide Chain Release factor
HRD54_RS01945	ENOG4107FB0	transcriptional regulator DeoR family
HRD54_RS01950	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HRD54_RS01960	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HRD54_RS01970	ENOG4105HX0	Transcriptional regulator
HRD54_RS01985	ENOG4105C7K	acetolactate synthase
HRD54_RS01990	ENOG4105M71	acetolactate synthase 1 regulatory subunit
HRD54_RS02010	ENOG4105C7N	Xanthine uracil vitamin C permease
HRD54_RS02015	ENOG4108MK9	spermidine N(1)-acetyltransferase
HRD54_RS02020	ENOG4105EEQ	Na H antiporter
HRD54_RS02025	ENOG4105EMK	carboxylate amino acid amine transporter
HRD54_RS02030	ENOG4105DZ2	Transcriptional regulator
HRD54_RS02035	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HRD54_RS02045	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
HRD54_RS02050	ENOG4107SXA	Phosphorylase
HRD54_RS02060	ENOG4108KF1	Membrane
HRD54_RS02065	ENOG4105CGY	Dna recombination protein
HRD54_RS02070	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HRD54_RS02075	ENOG4105JC1	sterol-binding domain protein
HRD54_RS02080	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HRD54_RS02085	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HRD54_RS02090	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HRD54_RS02095	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HRD54_RS02100	ENOG4105MDZ	Transcriptional activator rfaH
HRD54_RS02105	ENOG4105D7V	transposase
HRD54_RS02110	ENOG4108RS6	transposase
HRD54_RS02115	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HRD54_RS02120	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HRD54_RS02130	ENOG4105CHU	acetyl-coa acetyltransferase
HRD54_RS02135	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HRD54_RS02140	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HRD54_RS02145	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HRD54_RS02150	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HRD54_RS02155	ENOG4108RR8	protoporphyrinogen oxidase
HRD54_RS02185	ENOG4105C5A	transporter
HRD54_RS02190	ENOG4105E7W	lamb ycsf family protein
HRD54_RS02195	ENOG4105P4J	Allophanate hydrolase, subunit 1
HRD54_RS02200	ENOG4108JIK	carboxylase
HRD54_RS02205	ENOG4105HF0	Membrane
HRD54_RS02220	ENOG4105HEI	LysR family (Transcriptional regulator
HRD54_RS02225	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD54_RS02230	ENOG4105BZU	Histidine kinase
HRD54_RS02235	ENOG4105DQQ	Major facilitator superfamily MFS_1
HRD54_RS02240	ENOG4105CRU	nitrate reductase, alpha subunit
HRD54_RS02245	ENOG4108IUE	nitrate reductase beta subunit
HRD54_RS02250	ENOG4105R3A	Nitrate reductase
HRD54_RS02255	ENOG41076YT	nitrate reductase, gamma subunit
HRD54_RS02265	ENOG4105DIJ	Phosphoethanolamine transferase
HRD54_RS02280	ENOG4108JUA	Transcriptional regulator
HRD54_RS02305	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HRD54_RS02310	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HRD54_RS02325	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HRD54_RS02330	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HRD54_RS02335	ENOG4105CXY	transporter
HRD54_RS02340	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HRD54_RS02350	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HRD54_RS02360	ENOG4105EX9	Membrane
HRD54_RS02365	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HRD54_RS02375	ENOG4105D7V	transposase
HRD54_RS02390	ENOG4105C59	p-type ATPase
HRD54_RS02395	ENOG4107FS9	Membrane
HRD54_RS02405	ENOG4105MG3	Membrane
HRD54_RS02410	ENOG4106H78	methyltransferase
HRD54_RS02415	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HRD54_RS02420	ENOG4105CAK	Cell division ATP-binding protein ftsE
HRD54_RS02425	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HRD54_RS02430	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD54_RS02435	ENOG4105BZW	Glycerate kinase
HRD54_RS02440	ENOG4105U59	-acetyltransferase
HRD54_RS02450	ENOG4108INS	Transcriptional regulator
HRD54_RS02455	ENOG4108K0D	peptidase, M48
HRD54_RS02460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS02465	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS02475	ENOG4105BZ7	extracellular solute-binding protein family 1
HRD54_RS02480	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HRD54_RS02485	ENOG4105DJ2	Major Facilitator Superfamily
HRD54_RS02510	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HRD54_RS02520	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HRD54_RS02525	ENOG4108IA2	Sodium pantothenate symporter
HRD54_RS02530	ENOG4105RG0	Membrane
HRD54_RS02535	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HRD54_RS02540	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HRD54_RS02545	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HRD54_RS02550	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HRD54_RS02560	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HRD54_RS02565	ENOG4105VQ7	Rod shape-determining protein MreD
HRD54_RS02570	ENOG4108Z03	MAF-like protein
HRD54_RS02575	ENOG4105C03	ribonuclease
HRD54_RS02580	ENOG4105QD6	exported protein
HRD54_RS02590	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HRD54_RS02600	ENOG41067XF	inhibitor
HRD54_RS02605	ENOG4105N42	UPF0307 protein
HRD54_RS02610	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HRD54_RS02615	ENOG4105NXH	GreA GreB family elongation factor
HRD54_RS02620	ENOG41080Z8	PHOSPHOCARRIER protein
HRD54_RS02625	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HRD54_RS02630	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HRD54_RS02635	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HRD54_RS02640	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD54_RS02645	ENOG4108IUZ	ABC transporter
HRD54_RS02650	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HRD54_RS02655	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HRD54_RS02660	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HRD54_RS02665	ENOG4105C2X	Arabinose 5-phosphate isomerase
HRD54_RS02670	ENOG4105FEU	K -dependent Na -Ca exchanger
HRD54_RS02675	ENOG4105DHJ	ABC, transporter
HRD54_RS02680	ENOG4105CY3	ABC transporter, permease
HRD54_RS02685	ENOG4107PE3	Mammalian cell entry related domain protein
HRD54_RS02690	ENOG4105E3I	toluene tolerance
HRD54_RS02700	ENOG4105VFK	BolA family
HRD54_RS02705	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HRD54_RS02715	ENOG4105C0H	protease
HRD54_RS02720	ENOG4105C0H	protease
HRD54_RS02725	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HRD54_RS02730	ENOG4105D6Z	AFG1 family ATPase
HRD54_RS02735	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HRD54_RS02740	ENOG4108UJD	30S ribosomal protein S9
HRD54_RS02745	ENOG4107MKT	Stringent starvation protein a
HRD54_RS02750	ENOG4105KB2	stringent starvation protein b
HRD54_RS02760	ENOG4105CH2	amidohydrolase
HRD54_RS02770	ENOG4105BZ8	glutamate synthase
HRD54_RS02775	ENOG4105CBC	glutamate synthase
HRD54_RS02780	ENOG4105BZU	Histidine kinase
HRD54_RS02785	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HRD54_RS02790	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HRD54_RS02795	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
HRD54_RS02800	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HRD54_RS02805	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HRD54_RS02810	ENOG4105KI2	Urea amidohydrolase subunit beta
HRD54_RS02815	ENOG4105CQM	Urea amidohydrolase subunit alpha
HRD54_RS02820	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HRD54_RS02825	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HRD54_RS02830	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HRD54_RS02835	ENOG4105W4M	Transport-associated protein
HRD54_RS02840	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HRD54_RS02845	ENOG41082RQ	UPF0102 protein
HRD54_RS02855	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HRD54_RS02865	ENOG4108CNN	domain protein
HRD54_RS02870	ENOG4105CWB	LysR family transcriptional Regulator
HRD54_RS02875	ENOG4108VBZ	doxx family
HRD54_RS02885	ENOG41090KG	Inner membrane protein YqjE
HRD54_RS02890	ENOG4105NE1	Conserved Protein
HRD54_RS02895	ENOG4106W5V	Membrane
HRD54_RS02900	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HRD54_RS02905	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRD54_RS02915	ENOG4107RAN	Peptidase, M16
HRD54_RS02920	ENOG4105CQ0	ABC transporter
HRD54_RS02925	ENOG4105PE1	Receptor
HRD54_RS02935	ENOG4108SF5	RNA Polymerase
HRD54_RS02945	ENOG4105C5H	ABC transporter
HRD54_RS02950	ENOG4107SC1	transglycosylase
HRD54_RS02955	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HRD54_RS02960	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRD54_RS02965	ENOG4105CVJ	phosphoglycerate mutase
HRD54_RS02970	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD54_RS02975	ENOG4108RH0	Crea protein
HRD54_RS02980	ENOG41065U4	response regulator
HRD54_RS02990	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HRD54_RS03005	ENOG4105D1Q	UPF0246 protein
HRD54_RS03010	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD54_RS03020	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HRD54_RS03025	ENOG4105CFG	Acts as a chaperone (By similarity)
HRD54_RS03030	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HRD54_RS03035	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRD54_RS03040	ENOG41063Z6	transcriptional regulator, lysR family
HRD54_RS03045	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HRD54_RS03055	ENOG4105DTN	riboflavin biosynthesis protein ribF
HRD54_RS03060	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HRD54_RS03065	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HRD54_RS03070	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HRD54_RS03075	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HRD54_RS03080	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HRD54_RS03090	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HRD54_RS03100	ENOG4105TNG	K13735 adhesin invasin
HRD54_RS03105	ENOG4105CV8	reductase
HRD54_RS03110	ENOG4108I6A	alcohol dehydrogenase
HRD54_RS03115	ENOG4108I0C	methyltransferase
HRD54_RS03120	ENOG4108K81	inner membrane protein YghB
HRD54_RS03125	ENOG4105C28	cystathionine
HRD54_RS03130	ENOG4105CWK	Biopolymer transport protein, ExbB
HRD54_RS03135	ENOG4108ZZF	transport protein (ExbD)
HRD54_RS03145	ENOG4105E3S	small subunit
HRD54_RS03150	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD54_RS03155	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
HRD54_RS03160	ENOG4105DPX	Hydrogenase, large subunit
HRD54_RS03165	ENOG4108USZ	hydrogenase
HRD54_RS03170	ENOG4108WGS	hydrogenase 2-specific chaperone
HRD54_RS03175	ENOG4107RSS	Hydrogenase accessory protein HypB
HRD54_RS03180	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
HRD54_RS03185	ENOG4105CQS	hydrogenase expression formation protein HypD
HRD54_RS03190	ENOG4105C45	hydrogenase expression formation protein (HypE)
HRD54_RS03195	ENOG41066VF	YeeE YedE family protein
HRD54_RS03205	ENOG4105DH7	May be involved in recombination (By similarity)
HRD54_RS03215	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HRD54_RS03220	ENOG41083KI	ribonuclease, T2
HRD54_RS03225	ENOG4105CGH	5'-nucleotidase
HRD54_RS03235	ENOG4105EYH	Exonuclease
HRD54_RS03240	ENOG4107RH8	nuclease SbcCD subunit D
HRD54_RS03245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRD54_RS03250	ENOG4105BZU	Histidine kinase
HRD54_RS03255	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HRD54_RS03290	ENOG4108NWD	Cytochrome
HRD54_RS03295	ENOG4108393	oxidoreductase Fe-S subunit
HRD54_RS03300	ENOG4105JVW	
HRD54_RS03305	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
HRD54_RS03310	ENOG4108PU5	4fe-4S ferredoxin, iron-sulfur binding domain protein
HRD54_RS03320	ENOG4105D3R	alkyl hydroperoxide reductase
HRD54_RS03325	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HRD54_RS03330	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HRD54_RS03335	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HRD54_RS03340	ENOG4105VIE	preprotein translocase, subunit YajC
HRD54_RS03345	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRD54_RS03350	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRD54_RS03355	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HRD54_RS03360	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HRD54_RS03365	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HRD54_RS03370	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HRD54_RS03375	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HRD54_RS03380	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HRD54_RS03385	ENOG4105ETE	Transcriptional regulator (LacI family
HRD54_RS03390	ENOG4108RVA	ribokinase
HRD54_RS03395	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HRD54_RS03400	ENOG4105CNN	ABC, transporter
HRD54_RS03405	ENOG4105C2J	ABC transporter
HRD54_RS03410	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HRD54_RS03415	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HRD54_RS03420	ENOG4105CTB	Polyprenyl synthetase
HRD54_RS03425	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HRD54_RS03430	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HRD54_RS03445	ENOG4107S0N	DJ-1 family
HRD54_RS03450	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HRD54_RS03455	ENOG4108VPT	UPF0234 protein
HRD54_RS03460	ENOG4107RDB	Major Facilitator
HRD54_RS03465	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HRD54_RS03470	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HRD54_RS03475	ENOG4105CCU	oxidase (Subunit III)
HRD54_RS03480	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HRD54_RS03485	ENOG4105E2S	oxidase) subunit II
HRD54_RS03490	ENOG4108NFH	Sugar hydrolase
HRD54_RS03495	ENOG4105C1J	atp-dependent rna helicase
HRD54_RS03500	ENOG4105EYM	Major Facilitator superfamily
HRD54_RS03505	ENOG4105IEY	(LipO)protein
HRD54_RS03510	ENOG4105M85	Bola protein
HRD54_RS03515	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HRD54_RS03520	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HRD54_RS03525	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HRD54_RS03530	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HRD54_RS03535	ENOG4105K70	DNA-binding protein
HRD54_RS03540	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HRD54_RS03545	ENOG4105KQC	Competence protein
HRD54_RS03550	ENOG4108TGP	Thioesterase superfamily protein
HRD54_RS03555	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HRD54_RS03560	ENOG4108XM1	transcriptional regulator AsnC family
HRD54_RS03565	ENOG4105BZ1	(ABC) transporter
HRD54_RS03570	ENOG4105BZ1	(ABC) transporter
HRD54_RS03575	ENOG4108YZA	Nitrogen regulatory protein pii
HRD54_RS03580	ENOG4105BZU	Histidine kinase
HRD54_RS03585	ENOG4105C29	acyl-CoA thioesterase
HRD54_RS03595	ENOG4105KF5	hemolysin expression-modulating protein
HRD54_RS03605	ENOG4105BZS	acriflavin resistance protein
HRD54_RS03610	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HRD54_RS03615	ENOG4107XI7	Tetr family transcriptional regulator
HRD54_RS03620	ENOG41090EX	DsrE family
HRD54_RS03625	ENOG4105EGS	Mechanosensitive ion channel
HRD54_RS03640	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HRD54_RS03645	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HRD54_RS03650	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HRD54_RS03655	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HRD54_RS03660	ENOG4105D22	carbon starvation protein
HRD54_RS03665	ENOG4105VCD	cytoplasmic protein
HRD54_RS03670	ENOG4105CKI	cobalamin synthesis protein
HRD54_RS03680	ENOG4105CEE	C4-dicarboxylate transporter
HRD54_RS03685	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HRD54_RS03695	ENOG4105UQX	Mate efflux family protein
HRD54_RS03700	ENOG4105DGA	Diaminopimelate dehydrogenase
HRD54_RS03710	ENOG4105EQN	UPF0261 protein
HRD54_RS03740	ENOG4108ZRK	uncharacterized protein yacC
HRD54_RS03745	ENOG4105E3B	Multicopper oxidase
HRD54_RS03750	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HRD54_RS03755	ENOG41077A9	carbonic anhydrase
HRD54_RS03760	ENOG4105DA5	(ABC) transporter
HRD54_RS03765	ENOG4105E3A	(ABC) transporter
HRD54_RS03770	ENOG41079KZ	Major Facilitator Superfamily
HRD54_RS03775	ENOG4105R71	cytoplasmic protein
HRD54_RS03780	ENOG4105D0M	Protease HtpX homolog
HRD54_RS03795	ENOG4105QAX	Iron-sulfur
HRD54_RS03800	ENOG4108J2R	molybdopterin oxidoreductase
HRD54_RS03810	ENOG4105DBE	peroxidase
HRD54_RS03825	ENOG4105WP5	
HRD54_RS03855	ENOG4106032	Glutathionylspermidine synthase
HRD54_RS03860	ENOG4105W8I	Transcriptional regulator
HRD54_RS03865	ENOG4105C6Z	Gluconate
HRD54_RS03870	ENOG4105BZC	d-serine deaminase
HRD54_RS03875	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS03880	ENOG4107RCV	ABC transporter, permease
HRD54_RS03885	ENOG4105C4Y	ABC transporter
HRD54_RS03890	ENOG4105CXY	transporter
HRD54_RS03895	ENOG4105BZU	Histidine kinase
HRD54_RS03900	ENOG4108KX4	response regulator
HRD54_RS03905	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HRD54_RS03910	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HRD54_RS03915	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HRD54_RS03920	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRD54_RS03925	ENOG4105DJ0	Poly(A) Polymerase
HRD54_RS03935	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRD54_RS03940	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HRD54_RS03945	ENOG4105CQ7	ATP-dependent helicase
HRD54_RS03950	ENOG4105BZ4	penicillin-binding protein
HRD54_RS03955	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HRD54_RS03960	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HRD54_RS03970	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HRD54_RS03980	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HRD54_RS03985	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRD54_RS03990	ENOG4105DXN	mazG family
HRD54_RS03995	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HRD54_RS04000	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HRD54_RS04005	ENOG4105C8P	)-transporter
HRD54_RS04010	ENOG4107RA9	decarboxylase
HRD54_RS04015	ENOG4105E9H	Lytic Murein transglycosylase
HRD54_RS04020	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HRD54_RS04025	ENOG4105D1A	Methyltransferase
HRD54_RS04030	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRD54_RS04035	ENOG4107RZZ	dna polymerase iii epsilon subunit
HRD54_RS04070	ENOG4105EHG	Permease protein
HRD54_RS04075	ENOG4105E0A	ABC, transporter
HRD54_RS04125	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HRD54_RS04130	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HRD54_RS04135	ENOG4105BZA	Phosphoglycerate kinase
HRD54_RS04140	ENOG4105D2N	Aldolase
HRD54_RS04145	ENOG4105YB8	TM2 domain containing protein
HRD54_RS04150	ENOG4105DUX	Transporter
HRD54_RS04155	ENOG4107UWN	reductase
HRD54_RS04165	ENOG4108V8F	Transcriptional regulator, MarR family
HRD54_RS04170	ENOG4105C94	Transporter
HRD54_RS04185	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HRD54_RS04190	ENOG4105HMV	Fimbrial protein
HRD54_RS04195	ENOG4106PG1	outer membrane usher protein
HRD54_RS04200	ENOG4108FZ9	Chaperone
HRD54_RS04205	ENOG4105UGQ	Fimbrial
HRD54_RS04210	ENOG4105NEV	Fimbrial
HRD54_RS04230	ENOG4108W9T	type 1 fimbriae regulatory protein
HRD54_RS04235	ENOG4105HMV	Fimbrial protein
HRD54_RS04240	ENOG4108ZJG	MrfB protein
HRD54_RS04245	ENOG4106PG1	outer membrane usher protein
HRD54_RS04250	ENOG4106P2F	Pfam:Pili_assembly_C
HRD54_RS04265	ENOG4105H8W	Fimbrial protein
HRD54_RS04280	ENOG4105CFC	Transporter
HRD54_RS04285	ENOG4105VTS	DnaJ-like, subfamily C
HRD54_RS04295	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD54_RS04300	ENOG4105DFG	type I secretion outer membrane protein
HRD54_RS04305	ENOG4107QZV	Type I secretion membrane fusion protein
HRD54_RS04310	ENOG4108JJ6	Type I secretion system ATPase
HRD54_RS04315	ENOG4105QNJ	serralysin (EC 3.4.24.40)
HRD54_RS04350	ENOG4107URF	beta-phospho-glucomutase
HRD54_RS04355	ENOG4105C71	hydrolase family 65, central catalytic
HRD54_RS04360	ENOG4105C5Y	PTS System
HRD54_RS04365	ENOG4105D4X	repressor
HRD54_RS04395	ENOG4106PG1	outer membrane usher protein
HRD54_RS04400	ENOG4106P2F	Pfam:Pili_assembly_C
HRD54_RS04455	ENOG4108JJA	ABC, transporter
HRD54_RS04465	ENOG4108WUH	Transcriptional regulator, TetR family
HRD54_RS04470	ENOG4105D5Q	Arginine ornithine antiporter
HRD54_RS04475	ENOG4105CXN	decarboxylase
HRD54_RS04505	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HRD54_RS04510	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HRD54_RS04515	ENOG4105CEN	a g-specific adenine glycosylase
HRD54_RS04525	ENOG41090ED	Protein with unknown function (DUF469)
HRD54_RS04530	ENOG4105CSV	Glutaminase
HRD54_RS04535	ENOG4105K33	Periplasmic Protein
HRD54_RS04545	ENOG4105CSA	Coproporphyrinogen iii oxidase
HRD54_RS04550	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRD54_RS04555	ENOG4108VIA	integral membrane protein
HRD54_RS04560	ENOG4105II7	pyrroline-5-carboxylate reductase
HRD54_RS04565	ENOG4105DFA	alanine racemase domain protein
HRD54_RS04570	ENOG4105CZX	twitching motility protein
HRD54_RS04575	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HRD54_RS04580	ENOG4108UJU	UPF0301 protein
HRD54_RS04585	ENOG4105D7Z	glutathione synthase
HRD54_RS04590	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HRD54_RS04610	ENOG4105EJC	lysr family transcriptional regulator
HRD54_RS04615	ENOG4105RQF	LysR family Transcriptional regulator
HRD54_RS04625	ENOG4107QPN	acyl-Coa dehydrogenase
HRD54_RS04630	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HRD54_RS04635	ENOG4105E7A	Glutamine amidotransferase
HRD54_RS04640	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
HRD54_RS04645	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD54_RS04650	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD54_RS04655	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD54_RS04660	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD54_RS04665	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD54_RS04670	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HRD54_RS04675	ENOG4105CJ2	(LipO)protein
HRD54_RS04685	ENOG4105VDW	Csbd family
HRD54_RS04695	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HRD54_RS04700	ENOG4105E0K	tonB-dependent siderophore receptor
HRD54_RS04705	ENOG4105CIN	aminoacyl-histidine dipeptidase
HRD54_RS04710	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HRD54_RS04715	ENOG4105V1F	Fermentation respiration switch protein
HRD54_RS04720	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
HRD54_RS04725	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HRD54_RS04730	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HRD54_RS04735	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRD54_RS04740	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD54_RS04745	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HRD54_RS04750	ENOG4107TH8	cina domain protein
HRD54_RS04755	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HRD54_RS04760	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HRD54_RS04765	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HRD54_RS04795	ENOG4105D9M	gamma-glutamylcysteine synthetase
HRD54_RS04800	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HRD54_RS04805	ENOG4108JU6	CBS domain protein
HRD54_RS04810	ENOG4106KVJ	cytochrome C assembly protein
HRD54_RS04815	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRD54_RS04820	ENOG4105K5M	30s ribosomal protein S16
HRD54_RS04830	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HRD54_RS04835	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HRD54_RS04840	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD54_RS04860	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HRD54_RS04865	ENOG4105CQC	Prephenate dehydratase
HRD54_RS04870	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HRD54_RS04875	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRD54_RS04880	ENOG4105C34	Pseudouridine synthase
HRD54_RS04885	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HRD54_RS04890	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD54_RS04920	ENOG4105T42	(LipO)protein
HRD54_RS04925	ENOG4105JIM	Phosphatidylserine synthase
HRD54_RS04930	ENOG4105CD5	CoA-binding domain protein
HRD54_RS04935	ENOG4106IUH	DTW domain containing protein
HRD54_RS04940	ENOG4105Z6G	Protease that can act as an efficient and specific deubiquitinating enzyme in vitro. Does not possess desumoylating and deneddylating activities. The physiological substrate is
HRD54_RS04945	ENOG4105EIB	trna rrna methyltransferase
HRD54_RS04950	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD54_RS04955	ENOG4105CW7	secretion protein, HlyD family
HRD54_RS04965	ENOG4105C6X	Major Facilitator
HRD54_RS04970	ENOG4108UAU	isochorismatase
HRD54_RS04975	ENOG4105NTK	Transcriptional repressor Mpra
HRD54_RS04980	ENOG4105EQ0	Major Facilitator superfamily
HRD54_RS04985	ENOG4105X58	receptor
HRD54_RS04990	ENOG4105GIJ	Glycine betaine
HRD54_RS04995	ENOG4108HQS	Glycine betaine
HRD54_RS05000	ENOG4108IJ7	Glycine betaine
HRD54_RS05015	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HRD54_RS05040	ENOG4107Z6W	Protein CrcB homolog
HRD54_RS05045	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HRD54_RS05050	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HRD54_RS05055	ENOG4108Z43	UPF0250 protein
HRD54_RS05060	ENOG4105DZ1	carboxypeptidase
HRD54_RS05065	ENOG4105K6T	rare lipoprotein A
HRD54_RS05070	ENOG4105CNI	cell division protein FtsW
HRD54_RS05075	ENOG4105CJN	penicillin-binding protein
HRD54_RS05080	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HRD54_RS05085	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HRD54_RS05095	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HRD54_RS05100	ENOG4105DJF	DNA polymerase III, delta' subunit
HRD54_RS05105	ENOG4108U2H	Rare lipoprotein B
HRD54_RS05110	ENOG4105C8T	Leucyl-tRNA synthetase
HRD54_RS05115	ENOG4105CDA	abc transporter atp-binding protein
HRD54_RS05120	ENOG4105DRP	amino acid AbC transporter
HRD54_RS05125	ENOG4105EAD	ABC transporter
HRD54_RS05130	ENOG4107RP9	extracellular solute-binding protein, family 3
HRD54_RS05150	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRD54_RS05160	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HRD54_RS05165	ENOG4108JU5	Magnesium and cobalt efflux protein
HRD54_RS05170	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HRD54_RS05175	ENOG4105C9A	Phoh family
HRD54_RS05180	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HRD54_RS05185	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRD54_RS05190	ENOG4105C4W	S-formylglutathione hydrolase
HRD54_RS05240	ENOG4105E2R	ROK family
HRD54_RS05245	ENOG4105CE4	GlcNAc 6-P deacetylase
HRD54_RS05250	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HRD54_RS05255	ENOG4105CI1	PTS System
HRD54_RS05260	ENOG4105CX6	glutaminyL-tRNA synthetase
HRD54_RS05275	ENOG41090R7	Ferric uptake
HRD54_RS05280	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HRD54_RS05285	ENOG4105NNH	LexA regulated protein
HRD54_RS05290	ENOG4105EV9	Alpha Beta Hydrolase
HRD54_RS05295	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HRD54_RS05300	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HRD54_RS05305	ENOG4108W15	Protein of unknown function (DUF1456)
HRD54_RS05310	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
HRD54_RS05320	ENOG4105XIQ	Protein of unknown function (DUF2517)
HRD54_RS05325	ENOG4107QNR	UPF0135 protein
HRD54_RS05335	ENOG4105DEG	Vwa containing coxe family protein
HRD54_RS05340	ENOG4105RD5	
HRD54_RS05345	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
HRD54_RS05355	ENOG4105C2C	drug resistance transporter, Bcr CflA
HRD54_RS05365	ENOG4105BZN	citrate synthase
HRD54_RS05370	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HRD54_RS05375	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HRD54_RS05385	ENOG4105E33	succinate dehydrogenase
HRD54_RS05390	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HRD54_RS05395	ENOG4105C7S	Dehydrogenase
HRD54_RS05400	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HRD54_RS05405	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HRD54_RS05410	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD54_RS05415	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD54_RS05425	ENOG4105KJB	cyd operon protein YbgE
HRD54_RS05430	ENOG4105HEI	LysR family (Transcriptional regulator
HRD54_RS05435	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD54_RS05445	ENOG4107YD3	Thioesterase
HRD54_RS05450	ENOG4105E02	MotA TolQ exbB proton channel
HRD54_RS05460	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HRD54_RS05465	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HRD54_RS05470	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HRD54_RS05475	ENOG4105UFD	tol-pal system protein YbgF
HRD54_RS05495	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HRD54_RS05500	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD54_RS05505	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRD54_RS05510	ENOG4105DKW	ABC transporter
HRD54_RS05515	ENOG4105D5K	Hemolysin activator protein
HRD54_RS05530	ENOG4105F4R	Transcriptional regulator mode
HRD54_RS05540	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HRD54_RS05545	ENOG4105E0C	molybdate abc transporter
HRD54_RS05550	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS05555	ENOG4108K4B	hydrolase
HRD54_RS05560	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HRD54_RS05565	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HRD54_RS05570	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HRD54_RS05575	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRD54_RS05580	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD54_RS05585	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HRD54_RS05590	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HRD54_RS05600	ENOG4105CHW	UPF0052 protein
HRD54_RS05605	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRD54_RS05610	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRD54_RS05615	ENOG4105M00	molybdopterin converting factor, subunit 1
HRD54_RS05620	ENOG4108ZAF	Molybdopterin
HRD54_RS05625	ENOG4105HFZ	Membrane
HRD54_RS05630	ENOG4107QWP	ABC-2 type transporter
HRD54_RS05635	ENOG4107QWP	ABC-2 type transporter
HRD54_RS05640	ENOG4105CJ1	ABC, transporter
HRD54_RS05650	ENOG4107MVR	Transcriptional regulator
HRD54_RS05655	ENOG4105C1J	atp-dependent rna helicase
HRD54_RS05660	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HRD54_RS05670	ENOG4105KHC	sulfurtransferase
HRD54_RS05680	ENOG4105CEE	C4-dicarboxylate transporter
HRD54_RS05690	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HRD54_RS05695	ENOG4108PGP	mmge prpd family protein
HRD54_RS05700	ENOG4107NQ8	LysR family Transcriptional regulator
HRD54_RS05705	ENOG4105DVT	helicase
HRD54_RS05710	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HRD54_RS05720	ENOG4108URH	decarboxylase
HRD54_RS05735	ENOG4105D06	uba thif-type nad fad binding protein
HRD54_RS05740	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HRD54_RS05745	ENOG4105CBP	Major Facilitator
HRD54_RS05750	ENOG4105EUJ	GTP cyclohydrolase i
HRD54_RS05755	ENOG4105DHF	Membrane
HRD54_RS05760	ENOG4107GZ4	SanA protein
HRD54_RS05765	ENOG4107R1I	NAD-dependent malic enzyme
HRD54_RS05770	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HRD54_RS05775	ENOG41067MG	lrgb family
HRD54_RS05780	ENOG4105VAW	lrga family
HRD54_RS05785	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HRD54_RS05790	ENOG4105D1F	ATP-binding protein
HRD54_RS05795	ENOG4105DBI	uridine monophosphokinase
HRD54_RS05800	ENOG4105DHP	deoxycytidine triphosphate deaminase
HRD54_RS05805	ENOG4108GAE	asmA family
HRD54_RS05810	ENOG4105CEE	C4-dicarboxylate transporter
HRD54_RS05815	ENOG4105EE5	Membrane protein terC
HRD54_RS05825	ENOG4105D7V	transposase
HRD54_RS05830	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HRD54_RS05835	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
HRD54_RS05840	ENOG4105C0A	alcohol dehydrogenase
HRD54_RS05845	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HRD54_RS05850	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HRD54_RS05855	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HRD54_RS05860	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HRD54_RS05865	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HRD54_RS05875	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HRD54_RS05880	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HRD54_RS05885	ENOG4107SRH	Nad-dependent epimerase dehydratase
HRD54_RS05890	ENOG4108TGY	Glutathione S-transferase
HRD54_RS05895	ENOG4105DZ1	carboxypeptidase
HRD54_RS05900	ENOG4105CKU	formyltetrahydrofolate synthetase
HRD54_RS05905	ENOG4105EJQ	L-serine dehydratase
HRD54_RS05910	ENOG4105C44	Serine transporter
HRD54_RS05915	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HRD54_RS05920	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HRD54_RS05925	ENOG41090BQ	Glutaredoxin
HRD54_RS05930	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
HRD54_RS05935	ENOG4108RMJ	sensory transduction regulator
HRD54_RS05940	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HRD54_RS05945	ENOG4105DMR	ABC, transporter
HRD54_RS05950	ENOG4105GBT	ABC transporter
HRD54_RS05955	ENOG4106PMH	Extracellular solute-binding protein family 3
HRD54_RS05960	ENOG4105E5Z	arginine transporter ATP-binding subunit
HRD54_RS05965	ENOG4105CGD	Nad-dependent epimerase dehydratase
HRD54_RS05970	ENOG4105DWU	Membrane
HRD54_RS05975	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HRD54_RS05980	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD54_RS05985	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD54_RS05990	ENOG4105VEQ	Cold shock protein
HRD54_RS05995	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HRD54_RS06000	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD54_RS06010	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HRD54_RS06015	ENOG4108JJ8	(ABC) transporter
HRD54_RS06020	ENOG4108JJ9	ABC, transporter
HRD54_RS06025	ENOG4105C3M	thioredoxin reductase
HRD54_RS06030	ENOG4105EW9	transcriptional regulator AsnC family
HRD54_RS06035	ENOG4105CNU	cell division protein FtsK
HRD54_RS06040	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HRD54_RS06045	ENOG4105D1H	recombination factor protein RarA
HRD54_RS06050	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HRD54_RS06060	ENOG4105DG4	malate L-lactate dehydrogenase
HRD54_RS06070	ENOG4105F1A	Pyruvate formate-lyase
HRD54_RS06075	ENOG4105C6N	Formate acetyltransferase
HRD54_RS06080	ENOG4105TMB	Formate nitrite transporter
HRD54_RS06085	ENOG4105DDY	UPF0142 protein ycaO
HRD54_RS06090	ENOG4105HDK	L-asparaginase
HRD54_RS06095	ENOG4105CKT	filamentous hemagglutinin
HRD54_RS06105	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HRD54_RS06110	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HRD54_RS06115	ENOG4105CAT	Cytidine monophosphate kinase
HRD54_RS06120	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HRD54_RS06125	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRD54_RS06130	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HRD54_RS06135	ENOG4105BZ1	(ABC) transporter
HRD54_RS06140	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HRD54_RS06150	ENOG4105W49	UPF0434 protein
HRD54_RS06155	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HRD54_RS06160	ENOG4107S90	membrAne
HRD54_RS06165	ENOG4106371	Methyltransferase
HRD54_RS06170	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HRD54_RS06175	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HRD54_RS06180	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HRD54_RS06185	ENOG4108UY2	Chloramphenicol acetyltransferase
HRD54_RS06190	ENOG4105F0S	class B acid phosphatase
HRD54_RS06195	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HRD54_RS06200	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HRD54_RS06205	ENOG4105C5X	domain protein
HRD54_RS06210	ENOG4105GMB	type VI secretion system effector, hcp1 family
HRD54_RS06245	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD54_RS06295	ENOG4108WC9	type VI secretion system effector, hcp1 family
HRD54_RS06300	ENOG4105CS6	Rhs element vgr protein
HRD54_RS06400	ENOG4105CGF	Aromatic amino acid aminotransferase
HRD54_RS06405	ENOG4105FCK	Membrane
HRD54_RS06410	ENOG4105C5S	asparaginyl-tRNA synthetase
HRD54_RS06420	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HRD54_RS06425	ENOG4105CD8	aminopeptidase N
HRD54_RS06435	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HRD54_RS06440	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HRD54_RS06445	ENOG4105QVC	MOSC domain-containing protein
HRD54_RS06450	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HRD54_RS06455	ENOG4105C5H	ABC transporter
HRD54_RS06460	ENOG4105F1S	paraquat-inducible protein a
HRD54_RS06465	ENOG4105DY2	Paraquat-inducible protein b
HRD54_RS06470	ENOG4108Q2G	(LipO)protein
HRD54_RS06480	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HRD54_RS06485	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HRD54_RS06490	ENOG4105DAN	ATP-dependent protease
HRD54_RS06495	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HRD54_RS06515	ENOG4105EM2	membrane
HRD54_RS06520	ENOG41088T4	Helicase IV
HRD54_RS06525	ENOG4108Z5K	methylglyoxal synthase
HRD54_RS06530	ENOG4105K4P	CoA-binding domain protein
HRD54_RS06535	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
HRD54_RS06540	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HRD54_RS06545	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HRD54_RS06555	ENOG410849A	acetyltransferase, (GNAT) family
HRD54_RS06565	ENOG4108YS1	cytoplasmic protein
HRD54_RS06575	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HRD54_RS06580	ENOG4105HEI	LysR family (Transcriptional regulator
HRD54_RS06585	ENOG4105CV8	reductase
HRD54_RS06595	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD54_RS06615	ENOG4105D1S	lipid A biosynthesis
HRD54_RS06640	ENOG4105DTA	methyltransferase
HRD54_RS06650	ENOG410829K	Lysine exporter protein (Lyse ygga)
HRD54_RS06660	ENOG4105E68	Sulfatase
HRD54_RS06665	ENOG4105PAN	UPF0352 protein
HRD54_RS06670	ENOG4106V8H	Nucleoid-associated protein
HRD54_RS06675	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HRD54_RS06680	ENOG4105CFI	type iii restriction protein res subunit
HRD54_RS06685	ENOG4105I08	Pseudouridine synthase
HRD54_RS06690	ENOG4105C2C	drug resistance transporter, Bcr CflA
HRD54_RS06695	ENOG4105HG6	
HRD54_RS06700	ENOG4107TT5	NLP P60 protein
HRD54_RS06705	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HRD54_RS06720	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRD54_RS06735	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HRD54_RS06740	ENOG4105HMI	Membrane
HRD54_RS06745	ENOG4105DUM	transcriptional regulator, lysR family
HRD54_RS06750	ENOG4108IQI	permease
HRD54_RS06755	ENOG4105D05	Receptor
HRD54_RS06760	ENOG4105CUB	amino acid
HRD54_RS06770	ENOG4107RA9	decarboxylase
HRD54_RS06775	ENOG4105C5Q	Transcriptional regulator
HRD54_RS06780	ENOG4105CXG	d-lactate dehydrogenase
HRD54_RS06785	ENOG4105CJB	Exodeoxyribonuclease I
HRD54_RS06790	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
HRD54_RS06795	ENOG41090HJ	UPF0265 protein
HRD54_RS06800	ENOG4107QQB	Ribonuclease E
HRD54_RS06805	ENOG4105EI2	Pseudouridine synthase
HRD54_RS06815	ENOG4108UHJ	MAF-like protein
HRD54_RS06820	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HRD54_RS06825	ENOG4105VGS	50s ribosomal protein l32
HRD54_RS06830	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HRD54_RS06835	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HRD54_RS06840	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HRD54_RS06845	ENOG4105CHR	reductase
HRD54_RS06850	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HRD54_RS06855	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD54_RS06860	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HRD54_RS06865	ENOG4105HHA	aminodeoxychorismate lyase
HRD54_RS06870	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HRD54_RS06875	ENOG4107QRG	dna polymerase iii
HRD54_RS06880	ENOG4105F8V	Hydrolase, tatD family
HRD54_RS06885	ENOG4105K59	histidine triad (HIT) protein
HRD54_RS06890	ENOG41090DQ	Lipoprotein
HRD54_RS06895	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
HRD54_RS06900	ENOG4108KN0	Choline kinase
HRD54_RS06905	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HRD54_RS06910	ENOG4105D0Y	UPF0227 protein
HRD54_RS06915	ENOG4105CEP	NADH dehydrogenase
HRD54_RS06920	ENOG4107MBR	17 kDa surface antigen
HRD54_RS06925	ENOG4108JA2	transcriptioN-repair coupling factor
HRD54_RS06930	ENOG4105D60	lipoprotein releasing system transmembrane protein
HRD54_RS06940	ENOG4105D60	lipoprotein releasing system transmembrane protein
HRD54_RS06955	ENOG4105EZE	Cupin 4 family protein
HRD54_RS06960	ENOG4105IFJ	Histidine kinase
HRD54_RS06965	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HRD54_RS06970	ENOG4107QTF	adenylosuccinate lyase
HRD54_RS06975	ENOG41075W9	High frequency lysogenization protein HflD homolog
HRD54_RS06980	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HRD54_RS06990	ENOG4108R99	pseudouridine synthase
HRD54_RS06995	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HRD54_RS07000	ENOG4108I1J	Integrase
HRD54_RS07010	ENOG4108R7K	Metal Dependent Phosphohydrolase
HRD54_RS07050	ENOG4108MXB	Protein of unknown function (DUF968)
HRD54_RS07065	ENOG4105HRS	Antitermination protein
HRD54_RS07070	ENOG4105VEQ	Cold shock protein
HRD54_RS07075	ENOG4105R3P	Inner membrane protein yagU
HRD54_RS07085	ENOG4105E7U	AraC family transcriptional regulator
HRD54_RS07105	ENOG4105KUS	lysozyme
HRD54_RS07135	ENOG4105CAR	Terminase, large subunit
HRD54_RS07240	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HRD54_RS07260	ENOG4105VEQ	Cold shock protein
HRD54_RS07265	ENOG4108ZNX	Heat shock protein
HRD54_RS07275	ENOG4105KVH	Transcriptional regulator
HRD54_RS07280	ENOG4105ECR	NmrA family
HRD54_RS07290	ENOG4105DBI	uridine monophosphokinase
HRD54_RS07300	ENOG4105GTN	ParB Domain Protein Nuclease
HRD54_RS07305	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
HRD54_RS07310	ENOG4108WF3	methyltransferase
HRD54_RS07325	ENOG4107SEY	Conserved Protein
HRD54_RS07335	ENOG4105Z2P	Protein of unknown function (DUF465)
HRD54_RS07365	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HRD54_RS07370	ENOG4105HRS	Antitermination protein
HRD54_RS07380	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
HRD54_RS07385	ENOG4107SSZ	Phosphatase
HRD54_RS07400	ENOG4108RW8	Universal stress protein F
HRD54_RS07405	ENOG41090A1	ferritin
HRD54_RS07410	ENOG4105FXM	Copper resistance protein
HRD54_RS07415	ENOG4108PNC	copper resistance
HRD54_RS07420	ENOG4105NKT	exported protein
HRD54_RS07430	ENOG4105DY2	Paraquat-inducible protein b
HRD54_RS07435	ENOG4105H2K	paraquat-inducible protein a
HRD54_RS07440	ENOG4108ZGC	gaf domain protein
HRD54_RS07445	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HRD54_RS07450	ENOG4105CN1	protease
HRD54_RS07460	ENOG4105D0M	Protease HtpX homolog
HRD54_RS07470	ENOG4108ETY	sodium dicarboxylate symporter
HRD54_RS07475	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HRD54_RS07480	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HRD54_RS07485	ENOG4107PN8	YfeABCD locus regulator
HRD54_RS07495	ENOG4105CC5	ABC transporter
HRD54_RS07500	ENOG4105CC5	ABC transporter
HRD54_RS07505	ENOG4105DIK	(ABC) transporter
HRD54_RS07510	ENOG4105DSE	periplasmic solute binding protein
HRD54_RS07530	ENOG4108Z7R	Chaperone CsaA
HRD54_RS07540	ENOG4106PIH	fimbrial-like protein ydeQ
HRD54_RS07545	ENOG4105C22	threonyL-tRNA synthetase
HRD54_RS07550	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HRD54_RS07555	ENOG41082NX	50s ribosomal protein l35
HRD54_RS07560	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HRD54_RS07570	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HRD54_RS07575	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HRD54_RS07580	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRD54_RS07585	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HRD54_RS07590	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS07595	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD54_RS07600	ENOG4105CKK	Glycosyl transferase, family 2
HRD54_RS07605	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD54_RS07610	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD54_RS07615	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD54_RS07620	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HRD54_RS07625	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HRD54_RS07630	ENOG4108QBX	(LipO)protein
HRD54_RS07635	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HRD54_RS07645	ENOG4105D5U	fad dependent oxidoreductase
HRD54_RS07650	ENOG4107YCY	Transcriptional regulator
HRD54_RS07665	ENOG4107ZTW	SNARE associated Golgi
HRD54_RS07670	ENOG4105C7K	acetolactate synthase
HRD54_RS07730	ENOG4105C3G	gtp-binding protein
HRD54_RS07735	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HRD54_RS07740	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
HRD54_RS07745	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HRD54_RS07750	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HRD54_RS07755	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HRD54_RS07760	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HRD54_RS07765	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HRD54_RS07770	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HRD54_RS07775	ENOG41063JG	Transcriptional regulator
HRD54_RS07780	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HRD54_RS07785	ENOG4105N5T	Radical SAM Protein
HRD54_RS07795	ENOG4105CHH	sulfate transporter
HRD54_RS07805	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HRD54_RS07820	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HRD54_RS07830	ENOG4105EV4	Multidrug resistance protein mdtH
HRD54_RS07835	ENOG4105D9U	N-acetyltransferase
HRD54_RS07840	ENOG4105CJR	Integral membrane protein (MviN
HRD54_RS07850	ENOG4105C75	arginyL-tRNA synthetase
HRD54_RS07855	ENOG4106ZCM	YecM protein
HRD54_RS07860	ENOG4106N3A	copper homeostasis protein cutc
HRD54_RS07870	ENOG4105C5H	ABC transporter
HRD54_RS07875	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HRD54_RS07880	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HRD54_RS07885	ENOG4105WJG	Glutathione
HRD54_RS07890	ENOG4105C9M	aspartyl-trna synthetase
HRD54_RS07895	ENOG4108TIT	dATP pyrophosphohydrolase
HRD54_RS07900	ENOG4105CDY	transcriptional regulatory protein
HRD54_RS07905	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HRD54_RS07910	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HRD54_RS07915	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HRD54_RS07920	ENOG4108WC9	type VI secretion system effector, hcp1 family
HRD54_RS07925	ENOG4105CS6	Rhs element vgr protein
HRD54_RS07940	ENOG4105CNA	YD repeat protein
HRD54_RS07980	ENOG4105CNA	YD repeat protein
HRD54_RS08005	ENOG4105FAV	ABC, transporter
HRD54_RS08010	ENOG4105FDK	ABC transporter
HRD54_RS08015	ENOG4105NXV	High-affinity zinc uptake system protein
HRD54_RS08020	ENOG4105DR5	peptidase
HRD54_RS08025	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HRD54_RS08030	ENOG4105CA9	Pyruvate kinase
HRD54_RS08035	ENOG4106KNT	transcriptional regulator
HRD54_RS08040	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HRD54_RS08045	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HRD54_RS08050	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
HRD54_RS08055	ENOG4105CGD	Nad-dependent epimerase dehydratase
HRD54_RS08060	ENOG4105M4H	endoribonuclease L-psp
HRD54_RS08065	ENOG4105DVT	helicase
HRD54_RS08070	ENOG41072GX	Peptidase M22 Glycoprotease
HRD54_RS08075	ENOG4105Y4Z	Outer Membrane Lipoprotein
HRD54_RS08080	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD54_RS08085	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HRD54_RS08090	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HRD54_RS08095	ENOG4107QMS	site-determining protein
HRD54_RS08100	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HRD54_RS08105	ENOG4105VNG	YcgL domain-containing protein
HRD54_RS08110	ENOG4105CVE	Lytic murein transglycosylase
HRD54_RS08115	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HRD54_RS08120	ENOG4108ZZ3	UPF0260 protein
HRD54_RS08125	ENOG4105C4B	ABC transporter, permease
HRD54_RS08130	ENOG41083J0	(ABC) transporter
HRD54_RS08140	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD54_RS08150	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS08155	ENOG4105C5I	Dehydrogenase
HRD54_RS08160	ENOG4107H52	Dicarboxylate transport
HRD54_RS08165	ENOG410689M	(LipO)protein
HRD54_RS08170	ENOG4105WXT	Conserved Protein
HRD54_RS08195	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HRD54_RS08210	ENOG4105CQ7	ATP-dependent helicase
HRD54_RS08225	ENOG4105CW0	outer membrane usher protein
HRD54_RS08230	ENOG4108VCD	Chaperone
HRD54_RS08240	ENOG4105D5Q	Arginine ornithine antiporter
HRD54_RS08245	ENOG4105C5D	exported protein
HRD54_RS08250	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HRD54_RS08255	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HRD54_RS08260	ENOG4105Q9Y	Universal stress protein
HRD54_RS08265	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HRD54_RS08270	ENOG4107QY8	reductase
HRD54_RS08275	ENOG4105QAX	Iron-sulfur
HRD54_RS08300	ENOG4105NTW	Transcriptional regulator
HRD54_RS08315	ENOG4105D3R	alkyl hydroperoxide reductase
HRD54_RS08320	ENOG4108JU3	Alkyl hydroperoxide reductase
HRD54_RS08325	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD54_RS08395	ENOG4105FYV	Amp nucleosidase
HRD54_RS08400	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD54_RS08405	ENOG4105D44	asparaginase
HRD54_RS08410	ENOG4105D0S	secretion protein (HlyD
HRD54_RS08415	ENOG4105CJ1	ABC, transporter
HRD54_RS08420	ENOG4105CMI	transporter
HRD54_RS08425	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HRD54_RS08430	ENOG4105C08	Histidine kinase
HRD54_RS08435	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HRD54_RS08440	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HRD54_RS08445	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HRD54_RS08450	ENOG4107SNB	ankyrin repeat protein YahD
HRD54_RS08455	ENOG4107Y2X	deaminase
HRD54_RS08460	ENOG4108NEM	leader-binding protein dmsD
HRD54_RS08465	ENOG4107KGK	dmso reductase anchor subunit
HRD54_RS08470	ENOG4105QAX	Iron-sulfur
HRD54_RS08475	ENOG4107QY8	reductase
HRD54_RS08480	ENOG4105E98	transcriptional regulator DeoR family
HRD54_RS08500	ENOG4105CMT	Dihydroxyacetone kinase
HRD54_RS08510	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HRD54_RS08520	ENOG4105KME	endoribonuclease L-psp
HRD54_RS08545	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HRD54_RS08550	ENOG4105V0I	UPF0267 protein
HRD54_RS08555	ENOG4105C5H	ABC transporter
HRD54_RS08560	ENOG4105CPF	Cell wall formation (By similarity)
HRD54_RS08565	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HRD54_RS08580	ENOG4105D01	(LipO)protein
HRD54_RS08585	ENOG4105C28	cystathionine
HRD54_RS08600	ENOG4105E5W	Transporter
HRD54_RS08605	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HRD54_RS08610	ENOG4105CBN	LysR family transcriptional regulator
HRD54_RS08630	ENOG4105C5H	ABC transporter
HRD54_RS08635	ENOG4108UPT	UPF0178 protein
HRD54_RS08640	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HRD54_RS08650	ENOG4105CNH	Multidrug resistance protein MdtL
HRD54_RS08665	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HRD54_RS08675	ENOG4105J12	Multidrug resistance protein mdtN
HRD54_RS08680	ENOG4108MI0	Resistance protein
HRD54_RS08685	ENOG4105DFG	type I secretion outer membrane protein
HRD54_RS08695	ENOG4105R8A	Heat shock protein
HRD54_RS08700	ENOG4105C5W	Aldolase
HRD54_RS08715	ENOG4105CMG	Carbohydrate kinase
HRD54_RS08720	ENOG4105C93	Xylose Isomerase
HRD54_RS08725	ENOG4105DFD	Na H antiporter
HRD54_RS08735	ENOG4105T16	Transcriptional regulator (AraC family)
HRD54_RS08740	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HRD54_RS08805	ENOG4105EMU	Dehydrogenase
HRD54_RS08810	ENOG4105M5Q	UPF0482 protein
HRD54_RS08820	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HRD54_RS08825	ENOG4105DAG	ROK family
HRD54_RS08830	ENOG4106NZI	LysR family Transcriptional regulator
HRD54_RS08835	ENOG4105D94	Major Facilitator Superfamily
HRD54_RS08840	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
HRD54_RS08845	ENOG4105C9Q	fumarate hydratase class II
HRD54_RS08850	ENOG4106J39	exported protein
HRD54_RS08860	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HRD54_RS08865	ENOG4105DHU	Bile acid
HRD54_RS08870	ENOG4105D9R	oxidoreductase
HRD54_RS08875	ENOG4105M9B	inner membrane protein ydgK
HRD54_RS08880	ENOG4105DGN	Electron transport complex
HRD54_RS08890	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HRD54_RS08900	ENOG4108UQQ	Electron transport complex
HRD54_RS08910	ENOG4105CSM	endonuclease III
HRD54_RS08915	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HRD54_RS08920	ENOG4108ZJT	translation initiation factor, Sui1
HRD54_RS08925	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HRD54_RS08930	ENOG4105CFV	Tetratricopeptide repeat protein
HRD54_RS08935	ENOG4105Q4A	inner membrane protein yciS
HRD54_RS08940	ENOG4105EYK	Phosphatidylglycerophosphatase B
HRD54_RS08945	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HRD54_RS08960	ENOG4107QM5	aconitate hydratase
HRD54_RS08970	ENOG4107R11	Transcriptional regulator
HRD54_RS08995	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD54_RS09000	ENOG4105RKX	Protein of unknown function (DUF2498)
HRD54_RS09005	ENOG4105ERU	peptidase
HRD54_RS09010	ENOG4105UBK	short-chain dehydrogenase reductase
HRD54_RS09015	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HRD54_RS09025	ENOG4105FE9	pseudouridine synthase
HRD54_RS09030	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HRD54_RS09035	ENOG4105DB7	PHP domain protein
HRD54_RS09040	ENOG4105CRQ	synthase (Component I)
HRD54_RS09045	ENOG4105DDQ	anthranilate synthase
HRD54_RS09050	ENOG4107QYG	anthranilate phosphoribosyltransferase
HRD54_RS09055	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HRD54_RS09060	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HRD54_RS09065	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HRD54_RS09075	ENOG4105EIF	outer membrane protein W
HRD54_RS09080	ENOG4108S3I	UPF0259 membrane protein
HRD54_RS09090	ENOG4107835	probably involved in intracellular septation (By similarity)
HRD54_RS09095	ENOG4105NAU	thioesterase Superfamily protein
HRD54_RS09110	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HRD54_RS09120	ENOG4108T1M	outer membrane protein x
HRD54_RS09125	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HRD54_RS09145	ENOG4107RX3	Mg2 transporter protein cora family protein
HRD54_RS09160	ENOG4107QSI	ABC, transporter
HRD54_RS09165	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HRD54_RS09180	ENOG4106K28	UPF0283 membrane protein
HRD54_RS09185	ENOG4105CM6	amino acid regulated cytosolic protein
HRD54_RS09195	ENOG4105FM1	phage shock protein C
HRD54_RS09200	ENOG4105YYT	phage shock protein B
HRD54_RS09205	ENOG41087YS	Phage shock protein A
HRD54_RS09210	ENOG4105E51	psp operon transcriptional activator
HRD54_RS09215	ENOG4108HIY	periplasmic
HRD54_RS09220	ENOG4108EKA	peptide transport system, permease
HRD54_RS09225	ENOG4108EU3	peptide transport system, permease
HRD54_RS09230	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HRD54_RS09235	ENOG4108JQ2	peptide transport system atp-binding protein
HRD54_RS09240	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HRD54_RS09245	ENOG4108K3A	Glutathione S-transferase
HRD54_RS09250	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HRD54_RS09255	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HRD54_RS09260	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HRD54_RS09265	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HRD54_RS09270	ENOG4108XTF	Outer Membrane Lipoprotein
HRD54_RS09280	ENOG4105XZD	Fe-S protein
HRD54_RS09285	ENOG4108UYE	Lactoylglutathione lyase
HRD54_RS09290	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HRD54_RS09295	ENOG4105D7V	transposase
HRD54_RS09300	ENOG4108RS6	transposase
HRD54_RS09305	ENOG4105M2J	Glutaredoxin
HRD54_RS09310	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HRD54_RS09325	ENOG4105HF0	Membrane
HRD54_RS09330	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRD54_RS09340	ENOG4105ETE	Transcriptional regulator (LacI family
HRD54_RS09345	ENOG4105F52	Transcriptional regulator
HRD54_RS09350	ENOG4105CZQ	inner membrane transport protein YdhC
HRD54_RS09355	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HRD54_RS09360	ENOG4108R6K	riboflavin synthase, subunit alpha
HRD54_RS09365	ENOG4107QI1	Mate efflux family protein
HRD54_RS09380	ENOG4105CA9	Pyruvate kinase
HRD54_RS09385	ENOG4105E5D	amino acid
HRD54_RS09390	ENOG4105CVK	Glutamate decarboxylase
HRD54_RS09400	ENOG4105KMX	major outer membrane lipoprotein
HRD54_RS09405	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HRD54_RS09410	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRD54_RS09415	ENOG4105C9B	Cysteine desulfurase
HRD54_RS09420	ENOG4105JRK	feS assembly protein SufD
HRD54_RS09425	ENOG4105C3K	feS assembly ATPase SufC
HRD54_RS09430	ENOG4105DIW	FeS assembly protein SUFB
HRD54_RS09435	ENOG4108Z4V	iron-sulfur cluster assembly
HRD54_RS09445	ENOG4105KA0	thioesterase Superfamily protein
HRD54_RS09450	ENOG4105CQB	FAD linked oxidase domain protein
HRD54_RS09455	ENOG4105IPI	Membrane
HRD54_RS09460	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HRD54_RS09465	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HRD54_RS09470	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD54_RS09475	ENOG4107F3C	Hemin uptake protein
HRD54_RS09480	ENOG4107ENK	receptor
HRD54_RS09485	ENOG4107ENK	receptor
HRD54_RS09490	ENOG4106QJH	hemin transport protein
HRD54_RS09495	ENOG4107R4I	Periplasmic binding protein
HRD54_RS09500	ENOG4105EHG	Permease protein
HRD54_RS09505	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS09510	ENOG4105EW9	transcriptional regulator AsnC family
HRD54_RS09515	ENOG4105N14	lysine exporter protein LysE YggA
HRD54_RS09520	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD54_RS09525	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD54_RS09530	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD54_RS09545	ENOG4105KAF	membrAne
HRD54_RS09550	ENOG4105D5M	phosphate starvation-inducible protein
HRD54_RS09560	ENOG4105RWS	endonuclease I
HRD54_RS09570	ENOG4107XM3	UPF0442 protein
HRD54_RS09575	ENOG4105DWK	Membrane
HRD54_RS09595	ENOG410657R	replicase EC 2.7
HRD54_RS09600	ENOG4108U51	Universal stress protein
HRD54_RS09610	ENOG4108U51	Universal stress protein
HRD54_RS09615	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HRD54_RS09620	ENOG4105XVG	cytoplasmic protein
HRD54_RS09630	ENOG4105D52	delta-aminolevulinic acid dehydratase
HRD54_RS09640	ENOG4105DZC	cytosine deaminase
HRD54_RS09645	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HRD54_RS09650	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HRD54_RS09655	ENOG4105C26	Dehydrogenase
HRD54_RS09660	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HRD54_RS09665	ENOG4105C94	Transporter
HRD54_RS09670	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HRD54_RS09680	ENOG4108M66	Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity)
HRD54_RS09685	ENOG4105CW0	outer membrane usher protein
HRD54_RS09690	ENOG4108AF8	Chaperone
HRD54_RS09695	ENOG4108S54	Fimbrial protein
HRD54_RS09700	ENOG4108WDE	Fimbrial protein
HRD54_RS09705	ENOG4105ZUU	Transcriptional regulator
HRD54_RS09710	ENOG4108JQ7	(ABC) transporter
HRD54_RS09715	ENOG4105C3U	ABC transporter
HRD54_RS09720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS09725	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS09730	ENOG4107QSI	ABC, transporter
HRD54_RS09735	ENOG4107QSI	ABC, transporter
HRD54_RS09745	ENOG4105WZK	nitrite reductase NADPH small subunit
HRD54_RS09750	ENOG4107QZF	nitrite reductase NADPH large subunit
HRD54_RS09760	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS09765	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS09775	ENOG4108JQ7	(ABC) transporter
HRD54_RS09780	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HRD54_RS09785	ENOG4105C0A	alcohol dehydrogenase
HRD54_RS09790	ENOG4107104	thymidine kinase
HRD54_RS09805	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRD54_RS09810	ENOG4105I93	response regulator
HRD54_RS09815	ENOG4105K5B	UPF0225 protein
HRD54_RS09820	ENOG4105CIY	formyltetrahydrofolate deformylase
HRD54_RS09830	ENOG4105ETT	transcriptional Regulator, LysR family
HRD54_RS09835	ENOG4105CGK	Exodeoxyribonuclease III
HRD54_RS09840	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD54_RS09845	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HRD54_RS09850	ENOG41069NU	Nitroreductase
HRD54_RS09855	ENOG4105D07	Signal peptide peptidase, SppA
HRD54_RS09860	ENOG4105HDK	L-asparaginase
HRD54_RS09865	ENOG4108RWI	nicotinamidase
HRD54_RS09870	ENOG4105VUT	cytoplasmic protein
HRD54_RS09875	ENOG4105E0X	reductase
HRD54_RS09885	ENOG4105DSB	aldose 1-epimerase
HRD54_RS09890	ENOG4105GNX	MltA-interacting MipA family protein
HRD54_RS09895	ENOG4105C8H	hydrogenase maturation protein Hypf
HRD54_RS09900	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HRD54_RS09905	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HRD54_RS09910	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
HRD54_RS09915	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRD54_RS09920	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HRD54_RS09930	ENOG410814C	multidrug resistance protein
HRD54_RS09935	ENOG4105F27	Major Facilitator
HRD54_RS09950	ENOG4105D7X	high-affinity nickel-transporter
HRD54_RS09955	ENOG41065CD	Exported protein
HRD54_RS09985	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HRD54_RS09990	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HRD54_RS09995	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD54_RS10000	ENOG4108TVJ	Nitroreductase
HRD54_RS10005	ENOG4105CBT	Fructose-1,6-bisphosphatase
HRD54_RS10010	ENOG41080QX	K07048 phosphotriesterase-related protein
HRD54_RS10025	ENOG4108RVA	ribokinase
HRD54_RS10045	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HRD54_RS10070	ENOG4108VEN	abc transporter atp-binding protein
HRD54_RS10080	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
HRD54_RS10085	ENOG4105DKT	Transcriptional regulator
HRD54_RS10090	ENOG4105VF7	tolerance protein
HRD54_RS10105	ENOG410756H	nucleotidyltransferase
HRD54_RS10190	ENOG4105CKK	Glycosyl transferase, family 2
HRD54_RS10195	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
HRD54_RS10285	ENOG4108N0N	Phage Terminase Large Subunit
HRD54_RS10315	ENOG4105QBX	endodeoxyribonuclease RusA
HRD54_RS10400	ENOG4105DFP	Integrase
HRD54_RS10405	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HRD54_RS10410	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HRD54_RS10415	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HRD54_RS10425	ENOG4105CUG	Oligopeptidase b
HRD54_RS10440	ENOG4105C6K	Malic enzyme
HRD54_RS10445	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD54_RS10455	ENOG4105KUZ	arsenate reductase
HRD54_RS10460	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HRD54_RS10475	ENOG4105D7V	transposase
HRD54_RS10480	ENOG4105WD1	Membrane
HRD54_RS10485	ENOG4105XYK	UPF0370 protein
HRD54_RS10490	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HRD54_RS10495	ENOG4108VMM	UPF0756 membrane protein
HRD54_RS10500	ENOG4105CGZ	zinc metallopeptidase
HRD54_RS10505	ENOG4105C8V	SAICAR synthetase
HRD54_RS10510	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD54_RS10515	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HRD54_RS10520	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HRD54_RS10525	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRD54_RS10530	ENOG4105C02	permease
HRD54_RS10535	ENOG4105ERG	peptidase m48, ste24p
HRD54_RS10540	ENOG4105K89	arsenate reductase
HRD54_RS10545	ENOG4105EAA	nucleoside
HRD54_RS10550	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HRD54_RS10555	ENOG4105CUY	Mechanosensitive ion channel
HRD54_RS10560	ENOG4105C2W	permease
HRD54_RS10565	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HRD54_RS10570	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HRD54_RS10575	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HRD54_RS10580	ENOG4108MK9	spermidine N(1)-acetyltransferase
HRD54_RS10585	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HRD54_RS10590	ENOG4105C9X	ppx gppa phosphatase
HRD54_RS10595	ENOG4105CJW	magnesium transporter
HRD54_RS10605	ENOG4105CSH	Transporter
HRD54_RS10620	ENOG4105DUX	Transporter
HRD54_RS10625	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRD54_RS10630	ENOG4105BZS	acriflavin resistance protein
HRD54_RS10635	ENOG4105BZS	acriflavin resistance protein
HRD54_RS10640	ENOG4105EB3	Histidine kinase
HRD54_RS10645	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD54_RS10650	ENOG4105CFP	Peptidase U32
HRD54_RS10655	ENOG4107TE5	Lipid kinase
HRD54_RS10660	ENOG4105EIE	fructose-bisphosphate aldolase
HRD54_RS10665	ENOG4105DWF	phosphomethylpyrimidine kinase
HRD54_RS10675	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
HRD54_RS10680	ENOG4105C85	amino acid
HRD54_RS10690	ENOG4108W3Q	Transcriptional regulator
HRD54_RS10695	ENOG410667J	hydrolase
HRD54_RS10700	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HRD54_RS10705	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD54_RS10710	ENOG4105BZG	amino acid carrier protein
HRD54_RS10715	ENOG4105MPK	DNA polymerase III subunit theta
HRD54_RS10725	ENOG4105X5C	UPF0181 protein
HRD54_RS10730	ENOG4105CRQ	synthase (Component I)
HRD54_RS10735	ENOG4105P8F	nudix hydrolase
HRD54_RS10740	ENOG4105EJQ	L-serine dehydratase
HRD54_RS10745	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HRD54_RS10750	ENOG4105DHI	Methyltransferase
HRD54_RS10755	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HRD54_RS10760	ENOG41081QV	Universal stress protein
HRD54_RS10770	ENOG4108U51	Universal stress protein
HRD54_RS10775	ENOG4105C85	amino acid
HRD54_RS10785	ENOG4105CK7	Sodium proline symporter
HRD54_RS10790	ENOG4105C26	Dehydrogenase
HRD54_RS10795	ENOG4108M9K	flagella biosynthesis protein FliZ
HRD54_RS10800	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD54_RS10805	ENOG4105I03	Flagellin
HRD54_RS10815	ENOG4105DTS	flagellar hook-associated
HRD54_RS10820	ENOG4105MQ3	flagellar protein FliS
HRD54_RS10825	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
HRD54_RS10845	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HRD54_RS10850	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HRD54_RS10855	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD54_RS10860	ENOG41090PJ	Flagellar assembly protein
HRD54_RS10865	ENOG4108JIR	Flagellum-specific ATP synthase
HRD54_RS10870	ENOG4105GSA	Flagellar export protein flij
HRD54_RS10875	ENOG4105WF4	Flagellar hook-length control protein
HRD54_RS10880	ENOG4107ZI8	flagellar basal body-associated protein flil
HRD54_RS10885	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD54_RS10890	ENOG4105DD5	Flagellar motor switch protein
HRD54_RS10895	ENOG4105K0P	flagellar biosynthesis protein
HRD54_RS10900	ENOG4105CN7	Flagellar biosynthetic protein FliP
HRD54_RS10910	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HRD54_RS10915	ENOG4105DTJ	flagellar hook-associated protein
HRD54_RS10920	ENOG4105E1Q	flagellar hook-associated protein
HRD54_RS10925	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HRD54_RS10930	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HRD54_RS10935	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HRD54_RS10940	ENOG4105CGA	flagellar basal-body rod protein FlgG
HRD54_RS10945	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HRD54_RS10950	ENOG4105BZE	flagellar hook protein, FlgE
HRD54_RS10955	ENOG4105W00	Flagellar hook capping protein
HRD54_RS10960	ENOG4108ZC9	flagellar basal-body rod protein flgc
HRD54_RS10965	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HRD54_RS10970	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HRD54_RS10975	ENOG4105M9M	anti-sigma28 factor FlgM
HRD54_RS10980	ENOG4105QVD	Flagella synthesis protein FlgN
HRD54_RS10985	ENOG4105CKT	filamentous hemagglutinin
HRD54_RS10990	ENOG4105D7B	Flagellar biosynthesis protein flha
HRD54_RS10995	ENOG4105D00	flagellar biosynthetic protein flhB
HRD54_RS11005	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HRD54_RS11010	ENOG4108VYJ	response regulator receiver protein
HRD54_RS11015	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HRD54_RS11020	ENOG4105BZU	Histidine kinase
HRD54_RS11025	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS11030	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS11035	ENOG4108V3W	Chemotaxis protein, CheW
HRD54_RS11040	ENOG4105CBS	Chea signal transduction histidine kinase
HRD54_RS11045	ENOG4105ER2	Ompa motb domain protein
HRD54_RS11050	ENOG4107RD7	Flagellar Motor Protein, MotA
HRD54_RS11055	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HRD54_RS11060	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HRD54_RS11065	ENOG4105KT7	mgtC SapB transporter
HRD54_RS11080	ENOG4105GSJ	Inner membrane protein ylaC
HRD54_RS11105	ENOG4105EKE	dihydroorotase
HRD54_RS11110	ENOG4105PVA	Biofilm formation regulatory protein BssS
HRD54_RS11120	ENOG4105DB1	molybdopterin oxidoreductase
HRD54_RS11125	ENOG4106WHD	Tetrathionate reductase
HRD54_RS11130	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD54_RS11135	ENOG4106AFQ	Histidine kinase
HRD54_RS11140	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HRD54_RS11145	ENOG4105D1S	lipid A biosynthesis
HRD54_RS11150	ENOG4105C6X	Major Facilitator
HRD54_RS11155	ENOG4105DUX	Transporter
HRD54_RS11160	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HRD54_RS11180	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRD54_RS11205	ENOG4108UMN	azlc family
HRD54_RS11210	ENOG4105WBV	Transcriptional regulator
HRD54_RS11215	ENOG4105F0I	Aminotransferase
HRD54_RS11220	ENOG4108YK4	Acid-resistance membrane protein
HRD54_RS11225	ENOG4105CUY	Mechanosensitive ion channel
HRD54_RS11230	ENOG4107QY8	reductase
HRD54_RS11235	ENOG4105QAX	Iron-sulfur
HRD54_RS11240	ENOG4107KGK	dmso reductase anchor subunit
HRD54_RS11370	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
HRD54_RS11375	ENOG41068CG	regulatoR
HRD54_RS11380	ENOG4105BZU	Histidine kinase
HRD54_RS11385	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD54_RS11390	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HRD54_RS11395	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD54_RS11400	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD54_RS11405	ENOG4105XPH	Ferredoxin
HRD54_RS11410	ENOG4105M5B	(LipO)protein
HRD54_RS11415	ENOG4105E0U	tyrosine-specific transport protein
HRD54_RS11420	ENOG4108UII	YfaZ family
HRD54_RS11425	ENOG4105CH6	catalase
HRD54_RS11430	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD54_RS11435	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HRD54_RS11440	ENOG4108IPT	Naphthoate synthase
HRD54_RS11445	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HRD54_RS11450	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HRD54_RS11455	ENOG4105E4F	Isochorismate synthase
HRD54_RS11470	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD54_RS11475	ENOG4105C8S	subunit m
HRD54_RS11480	ENOG4105D65	subunit l
HRD54_RS11485	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD54_RS11490	ENOG4107UFS	subunit j
HRD54_RS11495	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD54_RS11500	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HRD54_RS11505	ENOG4108IEH	NADH dehydrogenase subunit g
HRD54_RS11510	ENOG4107QIZ	NADH dehydrogenase
HRD54_RS11515	ENOG4105GKE	subunit e
HRD54_RS11520	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD54_RS11525	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD54_RS11530	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRD54_RS11535	ENOG4107NQ8	LysR family Transcriptional regulator
HRD54_RS11540	ENOG4105CHM	Aminotransferase
HRD54_RS11545	ENOG4105DK2	UPF0207 protein
HRD54_RS11550	ENOG4107QWE	)-transporter
HRD54_RS11555	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HRD54_RS11560	ENOG4105XWI	UPF0304 protein
HRD54_RS11565	ENOG4105PQ6	UPF0208 membrane protein
HRD54_RS11570	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HRD54_RS11575	ENOG4105C6K	Malic enzyme
HRD54_RS11595	ENOG4105DZG	Dehydrogenase
HRD54_RS11600	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HRD54_RS11605	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HRD54_RS11615	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HRD54_RS11625	ENOG4105PTV	Nudix Hydrolase
HRD54_RS11630	ENOG4105CYM	Glutathione S-transferase
HRD54_RS11635	ENOG4105ECP	epimerase
HRD54_RS11640	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HRD54_RS11645	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HRD54_RS11650	ENOG4105E96	Colicin v production protein
HRD54_RS11655	ENOG4108S3P	Sporulation domain protein
HRD54_RS11660	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HRD54_RS11665	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HRD54_RS11670	ENOG4105DQR	SNARE associated Golgi
HRD54_RS11675	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HRD54_RS11680	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRD54_RS11685	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HRD54_RS11690	ENOG4105Z68	AraC Family Transcriptional Regulator
HRD54_RS11695	ENOG410631K	Membrane
HRD54_RS11700	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD54_RS11705	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HRD54_RS11710	ENOG4105XYF	acetyltransferase
HRD54_RS11720	ENOG4105MH2	YfcL protein
HRD54_RS11725	ENOG4108BPE	-transporting atpase
HRD54_RS11730	ENOG4105EJ9	Membrane
HRD54_RS11735	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HRD54_RS11740	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HRD54_RS11750	ENOG4108DG9	Smr protein MutS2
HRD54_RS11755	ENOG4108BY2	phosphohistidine phosphatase
HRD54_RS11760	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HRD54_RS11765	ENOG4105CHU	acetyl-coa acetyltransferase
HRD54_RS11770	ENOG4105KZW	UPF0381 protein
HRD54_RS11775	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HRD54_RS11780	ENOG410903C	(LipO)protein
HRD54_RS11790	ENOG4105MPK	DNA polymerase III subunit theta
HRD54_RS11930	ENOG4108V2F	protein ybcN in lambdoid DLP12 prophage regi
HRD54_RS11955	ENOG4105CDU	Replicative dna helicase
HRD54_RS12040	ENOG41076J9	exonuclease VIII
HRD54_RS12045	ENOG4108PNI	recT protein
HRD54_RS12050	ENOG4105Z8H	single-stranded DNA-binding protein
HRD54_RS12110	ENOG4108J2R	molybdopterin oxidoreductase
HRD54_RS12115	ENOG4105QAX	Iron-sulfur
HRD54_RS12120	ENOG4108NWD	Cytochrome
HRD54_RS12125	ENOG4105ZUU	Transcriptional regulator
HRD54_RS12170	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HRD54_RS12185	ENOG4105CHR	reductase
HRD54_RS12195	ENOG4105VRT	cytoplasmic protein
HRD54_RS12200	ENOG4105D9N	nucleoside
HRD54_RS12205	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HRD54_RS12210	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HRD54_RS12215	ENOG4105EXN	Sulfate transport protein CysZ
HRD54_RS12220	ENOG4105C6T	cysteine synthase
HRD54_RS12230	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HRD54_RS12235	ENOG4105C5Y	PTS System
HRD54_RS12240	ENOG4105C6T	cysteine synthase
HRD54_RS12245	ENOG4108IJ6	ABC transporter
HRD54_RS12250	ENOG4105ECW	sulfate abc transporter
HRD54_RS12255	ENOG4108I5D	sulfate abc transporter
HRD54_RS12260	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HRD54_RS12265	ENOG4105EZR	dyp-type peroxidase family protein
HRD54_RS12270	ENOG4105E7K	(LipO)protein
HRD54_RS12275	ENOG4108R6G	acetyltransferase
HRD54_RS12280	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HRD54_RS12290	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HRD54_RS12295	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD54_RS12300	ENOG4105N21	Membrane
HRD54_RS12305	ENOG4105CUT	histidyl-tRNA synthetase
HRD54_RS12310	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HRD54_RS12315	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HRD54_RS12325	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HRD54_RS12330	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HRD54_RS12335	ENOG4108JQB	penicillin-binding protein 1C
HRD54_RS12340	ENOG4105DN3	alpha-2-macroglobulin domain protein
HRD54_RS12345	ENOG4105YYA	enhanced serine sensitivity protein SseB
HRD54_RS12350	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HRD54_RS12355	ENOG4105WVQ	Fe-S assembly protein IscX
HRD54_RS12360	ENOG4108ZIT	Ferredoxin, 2FE-2S
HRD54_RS12365	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HRD54_RS12370	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HRD54_RS12375	ENOG4108Z4V	iron-sulfur cluster assembly
HRD54_RS12380	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HRD54_RS12385	ENOG4105C3J	Cysteine desulfurase
HRD54_RS12390	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HRD54_RS12395	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HRD54_RS12400	ENOG4105ECY	inositol monophosphatase
HRD54_RS12415	ENOG4105D8G	Major Facilitator superfamily
HRD54_RS12420	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HRD54_RS12425	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HRD54_RS12435	ENOG4108YZA	Nitrogen regulatory protein pii
HRD54_RS12440	ENOG4105C4K	Nad synthetase
HRD54_RS12445	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD54_RS12450	ENOG4108SKK	alpha helix protein
HRD54_RS12455	ENOG4107WP9	Histidine kinase
HRD54_RS12460	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HRD54_RS12465	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HRD54_RS12470	ENOG4108TH4	Major fimbrial subunit
HRD54_RS12475	ENOG4106PG1	outer membrane usher protein
HRD54_RS12480	ENOG4108FZ9	Chaperone
HRD54_RS12485	ENOG4108MDY	Fimbrial
HRD54_RS12490	ENOG4108YUF	Fimbrial
HRD54_RS12495	ENOG4108Z6B	deaminase
HRD54_RS12500	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HRD54_RS12505	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HRD54_RS12510	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HRD54_RS12515	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HRD54_RS12520	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HRD54_RS12525	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HRD54_RS12530	ENOG4105C3F	Signal peptidase i
HRD54_RS12535	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HRD54_RS12540	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HRD54_RS12545	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HRD54_RS12550	ENOG41069PW	sigma-e factor negative regulatory protein
HRD54_RS12555	ENOG4105EMN	RNA polymerase sigma factor
HRD54_RS12560	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HRD54_RS12565	ENOG4105C1J	atp-dependent rna helicase
HRD54_RS12570	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HRD54_RS12575	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HRD54_RS12580	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HRD54_RS12585	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HRD54_RS12590	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HRD54_RS12595	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD54_RS12600	ENOG4105VDB	UPF0125 protein
HRD54_RS12605	ENOG4108Z1B	Cyclase dehydrase
HRD54_RS12610	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HRD54_RS12645	ENOG4105DZR	Type I site-specific deoxyribonuclease
HRD54_RS12650	ENOG4105EKX	Restriction modification system DNA (Specificity
HRD54_RS12655	ENOG4105CVR	type I restriction-modification system
HRD54_RS12705	ENOG4105DWT	malate dehydrogenase (quinone)
HRD54_RS12720	ENOG4105NF4	modulator of drug activity
HRD54_RS12730	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HRD54_RS12735	ENOG4107QR9	Iron-sulfur cluster binding protein
HRD54_RS12740	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HRD54_RS12755	ENOG4105PI0	Ferredoxin
HRD54_RS12760	ENOG4108XC3	NADH ubiquinone oxidoreductase
HRD54_RS12770	ENOG4105NIV	Esterase
HRD54_RS12775	ENOG4105D05	Receptor
HRD54_RS12785	ENOG41060NJ	transcriptional regulator
HRD54_RS12790	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HRD54_RS12795	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HRD54_RS12800	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HRD54_RS12805	ENOG4105CMR	udp-glucose 4-epimerase
HRD54_RS12820	ENOG4108RW8	Universal stress protein F
HRD54_RS12825	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
HRD54_RS12830	ENOG4105Z2P	Protein of unknown function (DUF465)
HRD54_RS12835	ENOG4105VVZ	metal-binding protein
HRD54_RS12845	ENOG4105VXR	cytoplasmic protein
HRD54_RS12850	ENOG4108YYQ	gCN5-related N-acetyltransferase
HRD54_RS12905	ENOG4105CW0	outer membrane usher protein
HRD54_RS12910	ENOG4108VEV	chaperone
HRD54_RS12915	ENOG4105X0I	Fimbrial
HRD54_RS12940	ENOG4108T1M	outer membrane protein x
HRD54_RS12955	ENOG4105CRK	lysyL-tRNA synthetase
HRD54_RS12965	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HRD54_RS12970	ENOG4105T95	Thiol disulfide interChange protein
HRD54_RS12975	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD54_RS12980	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HRD54_RS12990	ENOG4105Y75	tpr repeat protein
HRD54_RS12995	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HRD54_RS13005	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HRD54_RS13010	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HRD54_RS13015	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HRD54_RS13020	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRD54_RS13025	ENOG4105D0A	hydroxylase
HRD54_RS13030	ENOG4107RAQ	aminopeptidase
HRD54_RS13035	ENOG4105E07	UPF0149 protein
HRD54_RS13040	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HRD54_RS13050	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HRD54_RS13060	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HRD54_RS13065	ENOG4108JJA	ABC, transporter
HRD54_RS13070	ENOG4108JQ1	Dehydrogenase
HRD54_RS13075	ENOG4105E66	phosphoriboisomerase A
HRD54_RS13080	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HRD54_RS13095	ENOG4105MPN	Membrane
HRD54_RS13100	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HRD54_RS13105	ENOG4105D64	Mechanosensitive ion channel
HRD54_RS13110	ENOG4108ZIG	UPF0231 protein
HRD54_RS13115	ENOG4107QIJ	Aconitate hydratase 2
HRD54_RS13130	ENOG4105EUK	rtx toxin RtxA
HRD54_RS13135	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRD54_RS13140	ENOG4107QSN	dihydrolipoamide acetyltransferase
HRD54_RS13145	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HRD54_RS13150	ENOG41073TP	transcriptional regulator
HRD54_RS13155	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD54_RS13160	ENOG4108ZUW	Major pilin subunit
HRD54_RS13165	ENOG4107QHF	type ii secretion system protein e
HRD54_RS13175	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HRD54_RS13180	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HRD54_RS13185	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HRD54_RS13195	ENOG4108I4D	hemolysin
HRD54_RS13200	ENOG4106IWJ	hemolysin
HRD54_RS13215	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HRD54_RS13220	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
HRD54_RS13230	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD54_RS13235	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HRD54_RS13240	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HRD54_RS13245	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HRD54_RS13255	ENOG4105DFU	Cell wall formation (By similarity)
HRD54_RS13260	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HRD54_RS13265	ENOG4105CNI	cell division protein FtsW
HRD54_RS13275	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HRD54_RS13280	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HRD54_RS13285	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HRD54_RS13290	ENOG4105CJN	penicillin-binding protein
HRD54_RS13295	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRD54_RS13300	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HRD54_RS13305	ENOG4108V6E	Cell division protein mraZ
HRD54_RS13310	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HRD54_RS13315	ENOG4108IQE	Amp-dependent synthetase and ligase
HRD54_RS13320	ENOG41064T2	transcriptional regulator, lysR family
HRD54_RS13325	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HRD54_RS13330	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HRD54_RS13335	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HRD54_RS13340	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HRD54_RS13345	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HRD54_RS13350	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HRD54_RS13360	ENOG4105VUH	addiction module killer protein
HRD54_RS13365	ENOG4105CHR	reductase
HRD54_RS13370	ENOG4105CYW	agmatinase
HRD54_RS13375	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HRD54_RS13380	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HRD54_RS13385	ENOG4105D1V	cellulose synthase operon protein YhjU
HRD54_RS13395	ENOG4105UTS	cellulose synthase operon protein YhjQ
HRD54_RS13400	ENOG4107QZ7	Cellulose synthase catalytic subunit
HRD54_RS13405	ENOG4107EEX	Cellulose synthase regulator protein
HRD54_RS13410	ENOG4105EJG	cellulose synthase
HRD54_RS13425	ENOG41080HT	Transcriptional regulator, arsr family
HRD54_RS13430	ENOG4105GPY	SprT protein
HRD54_RS13435	ENOG4105CJW	magnesium transporter
HRD54_RS13445	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HRD54_RS13450	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HRD54_RS13460	ENOG4105BZG	amino acid carrier protein
HRD54_RS13475	ENOG4107SVH	Potassium channel protein
HRD54_RS13480	ENOG4107QHE	Choloylglycine hydrolase
HRD54_RS13485	ENOG4108YYC	ycei family
HRD54_RS13490	ENOG4105DS1	cytochrome b561
HRD54_RS13510	ENOG4105CBG	Sulfatase
HRD54_RS13540	ENOG4105CHR	reductase
HRD54_RS13550	ENOG4105CE4	GlcNAc 6-P deacetylase
HRD54_RS13555	ENOG4105DAS	pts system
HRD54_RS13560	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD54_RS13565	ENOG4105ETZ	PTS System
HRD54_RS13570	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HRD54_RS13575	ENOG4105E70	isomerase
HRD54_RS13580	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HRD54_RS13585	ENOG4105E98	transcriptional regulator DeoR family
HRD54_RS13590	ENOG4105C4X	radical SAM domain protein
HRD54_RS13595	ENOG4105ENH	Sulfatase
HRD54_RS13605	ENOG4105D2N	Aldolase
HRD54_RS13610	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HRD54_RS13615	ENOG4108UHU	Aldolase
HRD54_RS13625	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HRD54_RS13630	ENOG4107ZY0	Phenazine biosynthesis-like protein
HRD54_RS13640	ENOG4105KBH	arsR family transcriptional regulator
HRD54_RS13650	ENOG4105RHY	Pfam:UPF0157
HRD54_RS13670	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HRD54_RS13675	ENOG4105WQ3	Rna-binding protein
HRD54_RS13680	ENOG4105DE4	1-phosphofructokinase
HRD54_RS13685	ENOG4105C8N	cysteinyl-tRNA synthetase
HRD54_RS13690	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HRD54_RS13695	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HRD54_RS13700	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HRD54_RS13705	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HRD54_RS13715	ENOG4105D64	Mechanosensitive ion channel
HRD54_RS13720	ENOG4105CV6	ABC transporter, permease
HRD54_RS13725	ENOG4108I0Y	(ABC) transporter
HRD54_RS13730	ENOG4108UJV	acyl-CoA thioesterase i
HRD54_RS13735	ENOG4105E1F	short-chain dehydrogenase reductase
HRD54_RS13740	ENOG4107QR8	Thioredoxin
HRD54_RS13745	ENOG4107QX8	SPFH domain, Band 7 family protein
HRD54_RS13755	ENOG4108Z6Z	Transcriptional regulator
HRD54_RS13760	ENOG4105C59	p-type ATPase
HRD54_RS13770	ENOG4105MBR	gumn family
HRD54_RS13775	ENOG4108Z66	YbaK ebsC protein
HRD54_RS13780	ENOG4105CGH	5'-nucleotidase
HRD54_RS13785	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HRD54_RS13790	ENOG4107RE1	Inosine-guanosine kinase
HRD54_RS13795	ENOG4108QY5	Ferric enterobactin transport protein
HRD54_RS13800	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HRD54_RS13805	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HRD54_RS13810	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HRD54_RS13815	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HRD54_RS13820	ENOG4105FR1	rard protein
HRD54_RS13825	ENOG4105D7K	pfkb domain protein
HRD54_RS13830	ENOG4108HKT	sucrose-6-phosphate hydrolase
HRD54_RS13835	ENOG4106NDP	Transcriptional regulator
HRD54_RS13840	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HRD54_RS13855	ENOG4108HPI	phosphatidate Cytidylyltransferase
HRD54_RS13865	ENOG4107653	Transcriptional regulator
HRD54_RS13875	ENOG4105C5B	carbamate kinase
HRD54_RS13880	ENOG4105G5A	Protein of unknown function (DUF2877)
HRD54_RS13885	ENOG4107REC	cytoplasmic protein
HRD54_RS13890	ENOG4107R1Q	Membrane protein FdrA
HRD54_RS13895	ENOG4105CHJ	isochorismatase hydrolase
HRD54_RS13900	ENOG4105EUB	pirin domain protein
HRD54_RS13910	ENOG4107QPK	)-transporter
HRD54_RS13935	ENOG4108T65	Fimbrial
HRD54_RS13940	ENOG4105CW0	outer membrane usher protein
HRD54_RS13950	ENOG4106EAR	Fimbrial protein
HRD54_RS13970	ENOG4106CXJ	Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR
HRD54_RS13980	ENOG4106P2F	Pfam:Pili_assembly_C
HRD54_RS13985	ENOG4106PG1	outer membrane usher protein
HRD54_RS13995	ENOG4105HMV	Fimbrial protein
HRD54_RS14005	ENOG4105DB7	PHP domain protein
HRD54_RS14010	ENOG4105C5Y	PTS System
HRD54_RS14015	ENOG4105CID	antiterminator
HRD54_RS14020	ENOG4105K5X	acetyltransferase
HRD54_RS14025	ENOG4105MZU	cell filamentation protein
HRD54_RS14060	ENOG4108X6F	Transcriptional regulator MerD
HRD54_RS14095	ENOG4105D6U	Sodium Glutamate Symporter
HRD54_RS14110	ENOG4108ZHR	arsR family transcriptional regulator
HRD54_RS14200	ENOG4108BUD	transposase
HRD54_RS14235	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HRD54_RS14265	ENOG4108BUD	transposase
HRD54_RS14285	ENOG4108BUD	transposase
HRD54_RS14295	ENOG4108BUD	transposase
HRD54_RS14310	ENOG410607W	Transposase
HRD54_RS14420	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD54_RS14445	ENOG4105DZR	Type I site-specific deoxyribonuclease
HRD54_RS14455	ENOG4105CVR	type I restriction-modification system
HRD54_RS14465	ENOG4107R08	Integrase
HRD54_RS14470	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HRD54_RS14480	ENOG4108K5P	(LipO)protein
HRD54_RS14485	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HRD54_RS14490	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HRD54_RS14495	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HRD54_RS14500	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HRD54_RS14505	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HRD54_RS14510	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRD54_RS14515	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HRD54_RS14520	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HRD54_RS14525	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HRD54_RS14530	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD54_RS14535	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HRD54_RS14540	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HRD54_RS14545	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HRD54_RS14550	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HRD54_RS14555	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HRD54_RS14560	ENOG4105C85	amino acid
HRD54_RS14610	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HRD54_RS14615	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS14620	ENOG4108UMI	ABC transporter, permease
HRD54_RS14625	ENOG4105D01	(LipO)protein
HRD54_RS14635	ENOG4108R96	Methyltransferase, YaeB family
HRD54_RS14640	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HRD54_RS14645	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HRD54_RS14650	ENOG4105M1T	rho-binding antiterminator
HRD54_RS14655	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HRD54_RS14660	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HRD54_RS14665	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HRD54_RS14670	ENOG4105C0B	DNA polymerase III (alpha subunit)
HRD54_RS14675	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRD54_RS14680	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD54_RS14685	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD54_RS14690	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HRD54_RS14695	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD54_RS14700	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HRD54_RS14705	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRD54_RS14715	ENOG4105KNE	Phosphatidate cytidylyltransferase
HRD54_RS14720	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HRD54_RS14725	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HRD54_RS14730	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HRD54_RS14735	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HRD54_RS14740	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HRD54_RS14745	ENOG4105CE9	30S ribosomal protein S2
HRD54_RS14750	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HRD54_RS14755	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HRD54_RS14760	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HRD54_RS14765	ENOG4108T8E	UPF0325 protein
HRD54_RS14770	ENOG4105QDK	Flavodoxin
HRD54_RS14780	ENOG4105CI1	PTS System
HRD54_RS14785	ENOG4105DR9	pseudouridine synthase
HRD54_RS14790	ENOG4105WP7	tRNA pseudouridine synthase C
HRD54_RS14795	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HRD54_RS14800	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HRD54_RS14805	ENOG4105EWT	decarboxylase family
HRD54_RS14810	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HRD54_RS14815	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HRD54_RS14820	ENOG4105M08	Membrane
HRD54_RS14825	ENOG4105ETT	transcriptional Regulator, LysR family
HRD54_RS14830	ENOG4105C9B	Cysteine desulfurase
HRD54_RS14835	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRD54_RS14840	ENOG4105CUZ	uba thif-type nad fad binding protein
HRD54_RS14845	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HRD54_RS14865	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRD54_RS14870	ENOG4107QZM	n-acetylglutamate synthase
HRD54_RS14875	ENOG4107QYX	exodeoxyribonuclease v alpha
HRD54_RS14880	ENOG4107QKA	exodeoxyribonuclease V beta
HRD54_RS14885	ENOG4107QXK	peptidase
HRD54_RS14890	ENOG4105DSY	exodeoxyribonuclease V, gamma
HRD54_RS14915	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HRD54_RS14920	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HRD54_RS14925	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HRD54_RS14930	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HRD54_RS14935	ENOG4105DP9	ABC transporter
HRD54_RS14940	ENOG4106SMU	thiamine transporter membrane protein
HRD54_RS14945	ENOG4107T0D	ABC, transporter
HRD54_RS14950	ENOG4105CQ2	DNA polymerase
HRD54_RS14955	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HRD54_RS14960	ENOG4105D3G	Pseudouridine synthase
HRD54_RS14965	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HRD54_RS14970	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HRD54_RS14975	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HRD54_RS14980	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HRD54_RS14985	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HRD54_RS14990	ENOG4105NWN	ApaG protein
HRD54_RS14995	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HRD54_RS15000	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HRD54_RS15015	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HRD54_RS15020	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HRD54_RS15025	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD54_RS15030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD54_RS15035	ENOG4105IPS	esterase
HRD54_RS15040	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HRD54_RS15045	ENOG41087AY	ADP-Ribose pyrophosphatase
HRD54_RS15050	ENOG4105DFG	type I secretion outer membrane protein
HRD54_RS15055	ENOG4105F1G	UPF0441 protein
HRD54_RS15060	ENOG4106032	Glutathionylspermidine synthase
HRD54_RS15065	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HRD54_RS15070	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HRD54_RS15075	ENOG4105W0Z	cytoplasmic protein
HRD54_RS15080	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HRD54_RS15085	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HRD54_RS15090	ENOG4105I7R	Adenylate cyclase
HRD54_RS15095	ENOG4106MWK	domain protein
HRD54_RS15100	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HRD54_RS15105	ENOG4107ZVW	dihydroneopterin aldolase
HRD54_RS15110	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HRD54_RS15130	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HRD54_RS15135	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRD54_RS15145	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HRD54_RS15150	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD54_RS15165	ENOG4105FFC	UPF0187 protein
HRD54_RS15175	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD54_RS15180	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD54_RS15185	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HRD54_RS15190	ENOG4105DUM	transcriptional regulator, lysR family
HRD54_RS15195	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS15200	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS15250	ENOG4105DAX	Pfam:DUF2983
HRD54_RS15315	ENOG4105CMT	Dihydroxyacetone kinase
HRD54_RS15320	ENOG4108UTZ	Dihydroxyacetone kinase
HRD54_RS15325	ENOG4105VDH	Dihydroxyacetone kinase
HRD54_RS15330	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
HRD54_RS15345	ENOG4105CXY	transporter
HRD54_RS15350	ENOG4105CA9	Pyruvate kinase
HRD54_RS15355	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HRD54_RS15365	ENOG4105D4T	Citrate transporter
HRD54_RS15370	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HRD54_RS15375	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HRD54_RS15380	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HRD54_RS15385	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HRD54_RS15390	ENOG4105D9N	nucleoside
HRD54_RS15395	ENOG4105EYA	deoxyribonuclease
HRD54_RS15400	ENOG4108NRW	Phospholipase, patatin family
HRD54_RS15410	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HRD54_RS15425	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HRD54_RS15435	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HRD54_RS15450	ENOG4105EAM	Na Pi-cotransporter
HRD54_RS15460	ENOG4105D7V	transposase
HRD54_RS15465	ENOG4108RS6	transposase
HRD54_RS15470	ENOG4105E93	esterase
HRD54_RS15480	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HRD54_RS15485	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HRD54_RS15490	ENOG4105EAC	phosphoserine phosphatase
HRD54_RS15495	ENOG41062Z9	Membrane
HRD54_RS15500	ENOG4105G0K	glycine radical enzyme YjjI family
HRD54_RS15505	ENOG41076CZ	activating enzyme
HRD54_RS15525	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS15540	ENOG4105K64	Glycosyl transferase, family 2
HRD54_RS15545	ENOG4108MG9	hydrogenase 3 maturation protease
HRD54_RS15550	ENOG4105I6X	formate hydrogenlyase maturation
HRD54_RS15555	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HRD54_RS15565	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD54_RS15570	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HRD54_RS15575	ENOG4107WQX	hydrogenase 4 membrane subunit
HRD54_RS15580	ENOG4105D65	subunit l
HRD54_RS15585	ENOG4107TDF	Formate hydrogenlyase subunit 4
HRD54_RS15590	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HRD54_RS15595	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HRD54_RS15600	ENOG4108YZG	isomerase
HRD54_RS15605	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRD54_RS15610	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HRD54_RS15620	ENOG4105CW0	outer membrane usher protein
HRD54_RS15660	ENOG4108ZVF	(LipO)protein
HRD54_RS15665	ENOG4105D7V	transposase
HRD54_RS15675	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HRD54_RS15680	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HRD54_RS15695	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HRD54_RS15700	ENOG4108SIC	Transcriptional regulator
HRD54_RS15715	ENOG4105HA9	of methanol dehydrogenase type
HRD54_RS15720	ENOG4108V0P	LemA family
HRD54_RS15735	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HRD54_RS15740	ENOG4105C54	Major Facilitator superfamily
HRD54_RS15745	ENOG4105WQV	ferredoxin-like protein
HRD54_RS15750	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HRD54_RS15770	ENOG4105C1G	acyl-Coa dehydrogenase
HRD54_RS15775	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HRD54_RS15780	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD54_RS15785	ENOG4106YT9	Enoyl-CoA hydratase
HRD54_RS15795	ENOG4108XNW	Transcriptional activatory protein CaiF
HRD54_RS15800	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD54_RS15805	ENOG4108M1A	Chitin-binding protein
HRD54_RS15810	ENOG4105Y3E	Modulates RecA activity (By similarity)
HRD54_RS15830	ENOG4108UR8	BAX protein
HRD54_RS15835	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HRD54_RS15855	ENOG4105C6Z	Gluconate
HRD54_RS15860	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HRD54_RS15865	ENOG4105DIQ	Transcriptional regulator
HRD54_RS15870	ENOG4105S10	periplasmic binding protein
HRD54_RS15875	ENOG4105EHG	Permease protein
HRD54_RS15880	ENOG4105E0A	ABC, transporter
HRD54_RS15885	ENOG4108BSC	Methyltransferase
HRD54_RS15890	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HRD54_RS15915	ENOG4108Z19	type iii secretion
HRD54_RS15920	ENOG4108M6W	surface presentation of antigens protein SpaS
HRD54_RS15925	ENOG4108TN6	type iii secretion
HRD54_RS15930	ENOG4105U07	type iii secretion
HRD54_RS15935	ENOG41075IY	surface presentation of antigens protein SpaP
HRD54_RS15955	ENOG4108JIR	Flagellum-specific ATP synthase
HRD54_RS15965	ENOG4108HR8	type iii secretion
HRD54_RS15970	ENOG4108N8R	Invasion protein
HRD54_RS15980	ENOG41090HZ	type iii secretion
HRD54_RS15990	ENOG4105Y7Q	type iii secretion
HRD54_RS16000	ENOG4108RBT	type iii secretion
HRD54_RS16020	ENOG4108Z4X	TRANSCRIPTIONal
HRD54_RS16035	ENOG4105BZS	acriflavin resistance protein
HRD54_RS16085	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
HRD54_RS16090	ENOG4105KNY	Microcompartments protein
HRD54_RS16095	ENOG4105F1A	Pyruvate formate-lyase
HRD54_RS16100	ENOG4105C6N	Formate acetyltransferase
HRD54_RS16115	ENOG4105C0A	alcohol dehydrogenase
HRD54_RS16120	ENOG4105KNY	Microcompartments protein
HRD54_RS16125	ENOG4105KNY	Microcompartments protein
HRD54_RS16130	ENOG4105KNY	Microcompartments protein
HRD54_RS16160	ENOG4108WDE	Fimbrial protein
HRD54_RS16165	ENOG4108AF8	Chaperone
HRD54_RS16170	ENOG4105CW0	outer membrane usher protein
HRD54_RS16175	ENOG4108SQA	Fimbrial
HRD54_RS16190	ENOG4108HM4	ABC transporter
HRD54_RS16195	ENOG4105D38	putrescine abc transporter
HRD54_RS16220	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRD54_RS16225	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HRD54_RS16230	ENOG4105CDU	Replicative dna helicase
HRD54_RS16235	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HRD54_RS16240	ENOG4105CGF	Aromatic amino acid aminotransferase
HRD54_RS16250	ENOG4105C44	Serine transporter
HRD54_RS16255	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HRD54_RS16260	ENOG4108UUM	single-stranded DNA-binding protein
HRD54_RS16265	ENOG4105MYN	Zinc uptake regulation protein
HRD54_RS16270	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HRD54_RS16275	ENOG41080IJ	Diacylglycerol kinase
HRD54_RS16280	ENOG4105E55	glycerol-3-phosphate acyltransferase
HRD54_RS16285	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HRD54_RS16290	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HRD54_RS16295	ENOG4107QP8	phosphohexose isomerase
HRD54_RS16300	ENOG4105CFH	Aspartokinase
HRD54_RS16315	ENOG4105C3R	Methionine synthase
HRD54_RS16320	ENOG41069M3	Transcriptional regulator
HRD54_RS16325	ENOG4105C01	Dihydroxy-acid dehydratase
HRD54_RS16330	ENOG4108UHU	Aldolase
HRD54_RS16340	ENOG4108I9X	Isocitrate lyase
HRD54_RS16345	ENOG4107QP3	malate synthase g
HRD54_RS16350	ENOG4105CVG	Homoserine O-transsuccinylase
HRD54_RS16390	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HRD54_RS16395	ENOG4105C12	Phosphoribosylglycinamide synthetase
HRD54_RS16400	ENOG4108T8B	Protein of unknown function (DUF1481)
HRD54_RS16410	ENOG4105R2J	Conserved Protein
HRD54_RS16415	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HRD54_RS16420	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HRD54_RS16425	ENOG4105E09	nadh pyrophosphatase
HRD54_RS16435	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HRD54_RS16440	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HRD54_RS16445	ENOG4105D06	uba thif-type nad fad binding protein
HRD54_RS16450	ENOG4105WHD	thiamine biosynthesis protein ThiS
HRD54_RS16455	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HRD54_RS16460	ENOG4105D41	biosynthesis protein thiH
HRD54_RS16465	ENOG4105DNE	Transposase
HRD54_RS16470	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD54_RS16475	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD54_RS16480	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HRD54_RS16485	ENOG4108VZM	50s ribosomal protein L10
HRD54_RS16490	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HRD54_RS16495	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HRD54_RS16500	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HRD54_RS16505	ENOG4105PM1	preprotein translocase subunit SecE
HRD54_RS16510	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRD54_RS16515	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HRD54_RS16520	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HRD54_RS16525	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HRD54_RS16535	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HRD54_RS16540	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HRD54_RS16545	ENOG4105WWK	YheO domain protein
HRD54_RS16555	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRD54_RS16560	ENOG4105VRX	Protein slyX homolog
HRD54_RS16565	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HRD54_RS16570	ENOG4105VKU	nucleicacid-binding protein
HRD54_RS16580	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HRD54_RS16585	ENOG4105C5H	ABC transporter
HRD54_RS16590	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS16595	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD54_RS16600	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRD54_RS16605	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
HRD54_RS16615	ENOG4105DNZ	Alpha Beta Hydrolase
HRD54_RS16625	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HRD54_RS16630	ENOG4108UKZ	OsmC family
HRD54_RS16640	ENOG4105C8Y	Acetylornithine aminotransferase
HRD54_RS16650	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HRD54_RS16660	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HRD54_RS16665	ENOG4105C2M	dna polymerase I
HRD54_RS16675	ENOG4108Z33	Thiol disulfide Interchange Protein
HRD54_RS16680	ENOG4105E27	serine threonine protein kinase
HRD54_RS16685	ENOG4105PC1	Conserved Protein
HRD54_RS16690	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HRD54_RS16695	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HRD54_RS16705	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HRD54_RS16710	ENOG4105DC8	reductase
HRD54_RS16715	ENOG4105D6S	protein involved in catabolism of external DNA
HRD54_RS16725	ENOG4107H3J	ribonuclease
HRD54_RS16730	ENOG4105VSH	4-oxalocrotonate tautomerase
HRD54_RS16735	ENOG4105CS0	peptidase
HRD54_RS16740	ENOG4105BZU	Histidine kinase
HRD54_RS16745	ENOG4105CKT	filamentous hemagglutinin
HRD54_RS16750	ENOG4108JQ7	(ABC) transporter
HRD54_RS16755	ENOG4105C3U	ABC transporter
HRD54_RS16760	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS16765	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS16770	ENOG4105DEF	Extracellular solute-binding protein, family 5
HRD54_RS16790	ENOG4105R2A	(LipO)protein
HRD54_RS16795	ENOG4105D0C	transport protein
HRD54_RS16800	ENOG4105JKW	Valine--pyruvate aminotransferase
HRD54_RS16805	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HRD54_RS16810	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HRD54_RS16815	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HRD54_RS16830	ENOG4105D99	atp gtp-binding protein
HRD54_RS16835	ENOG4105EN6	Membrane
HRD54_RS16840	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HRD54_RS16845	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HRD54_RS16850	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRD54_RS16855	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HRD54_RS16860	ENOG4105CB5	ATP-dependent DNA helicase recG
HRD54_RS16865	ENOG4105D6U	Sodium Glutamate Symporter
HRD54_RS16870	ENOG4105C2W	permease
HRD54_RS16875	ENOG4105JV1	AsmA family
HRD54_RS16885	ENOG4105FE9	pseudouridine synthase
HRD54_RS16890	ENOG4105SUU	thioesterase domain
HRD54_RS16895	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HRD54_RS16900	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
HRD54_RS16915	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HRD54_RS16945	ENOG4105GMB	type VI secretion system effector, hcp1 family
HRD54_RS16965	ENOG4105CI3	gtp-binding protein typa
HRD54_RS16985	ENOG4105D4P	Coproporphyrinogen iii oxidase
HRD54_RS16990	ENOG4107Y60	(LipO)protein
HRD54_RS17000	ENOG4106B0W	Curli production assembly transport component CsgG
HRD54_RS17005	ENOG4105BZM	domain protein
HRD54_RS17010	ENOG4108RRZ	Transcription elongation factor GreB
HRD54_RS17020	ENOG4105E0F	Histidine kinase
HRD54_RS17025	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HRD54_RS17030	ENOG4105C8U	phosphate abc transporter
HRD54_RS17035	ENOG4105E2Z	phosphate ABC transporter (Permease
HRD54_RS17045	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HRD54_RS17050	ENOG4105CT1	(ABC) transporter
HRD54_RS17055	ENOG4105E5Q	amino acid AbC transporter
HRD54_RS17060	ENOG4105DRP	amino acid AbC transporter
HRD54_RS17085	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HRD54_RS17100	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD54_RS17105	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HRD54_RS17110	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HRD54_RS17115	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HRD54_RS17120	ENOG4105CHR	reductase
HRD54_RS17125	ENOG41081XD	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HRD54_RS17135	ENOG4105C7N	Xanthine uracil vitamin C permease
HRD54_RS17140	ENOG4105D9U	N-acetyltransferase
HRD54_RS17160	ENOG4105XFK	Ferrous iron transport protein A
HRD54_RS17165	ENOG4105CE1	Ferrous iron transport protein b
HRD54_RS17170	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
HRD54_RS17180	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HRD54_RS17185	ENOG4105MJ2	Competence protein
HRD54_RS17190	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HRD54_RS17195	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HRD54_RS17200	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HRD54_RS17205	ENOG4105E98	transcriptional regulator DeoR family
HRD54_RS17210	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HRD54_RS17215	ENOG4105K78	MarR family Transcriptional regulator
HRD54_RS17220	ENOG4105SYT	Methylenetetrahydrofolate reductase
HRD54_RS17245	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HRD54_RS17255	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HRD54_RS17265	ENOG4105EF1	ribulokinase
HRD54_RS17275	ENOG4108S9F	abc transporter, atp-binding protein
HRD54_RS17290	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD54_RS17295	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HRD54_RS17300	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD54_RS17310	ENOG4108T1M	outer membrane protein x
HRD54_RS17315	ENOG410901P	UPF0249 protein
HRD54_RS17320	ENOG4105F8D	glycoside hydrolase family 4
HRD54_RS17325	ENOG4105EZV	Transcriptional regulator
HRD54_RS17330	ENOG4105VCP	PTS System
HRD54_RS17335	ENOG4105CK1	PTS System
HRD54_RS17340	ENOG4105VZJ	PTS System
HRD54_RS17350	ENOG4105DHS	permease protein
HRD54_RS17355	ENOG4105CM4	permease protein
HRD54_RS17360	ENOG4108IPW	abc transporter atp-binding protein
HRD54_RS17380	ENOG4107QY8	reductase
HRD54_RS17385	ENOG4105QAX	Iron-sulfur
HRD54_RS17390	ENOG4107KGK	dmso reductase anchor subunit
HRD54_RS17395	ENOG4105ETE	Transcriptional regulator (LacI family
HRD54_RS17405	ENOG4105EAA	nucleoside
HRD54_RS17410	ENOG4105KT7	mgtC SapB transporter
HRD54_RS17415	ENOG4105EXC	Acyl-transferase
HRD54_RS17430	ENOG4105QEK	Transcriptional regulator
HRD54_RS17435	ENOG4108R66	Conserved Protein
HRD54_RS17440	ENOG4107RJ1	sodium solute
HRD54_RS17450	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HRD54_RS17455	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HRD54_RS17460	ENOG4105C8J	)-transporter
HRD54_RS17470	ENOG4105CI1	PTS System
HRD54_RS17475	ENOG4108Q3X	Transcriptional regulator
HRD54_RS17485	ENOG4105D3G	Pseudouridine synthase
HRD54_RS17490	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HRD54_RS17495	ENOG4105N1F	Hnh endonuclease
HRD54_RS17500	ENOG4108WC9	type VI secretion system effector, hcp1 family
HRD54_RS17505	ENOG4105CS6	Rhs element vgr protein
HRD54_RS17550	ENOG4106PYX	Receptor
HRD54_RS17555	ENOG4108N3D	putative enzyme
HRD54_RS17585	ENOG4105DGW	oligopeptidase A
HRD54_RS17590	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HRD54_RS17595	ENOG4108R85	Short chain dehydrogenase
HRD54_RS17600	ENOG4105D82	Glutamate dehydrogenase
HRD54_RS17605	ENOG4108M6U	Universal stress protein A
HRD54_RS17610	ENOG4108V6B	universal stress protein B
HRD54_RS17615	ENOG4105CJ3	phosphate transporter
HRD54_RS17620	ENOG4105CBX	hi0933 family
HRD54_RS17625	ENOG4105C2I	pirin domain protein
HRD54_RS17630	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HRD54_RS17635	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HRD54_RS17640	ENOG4105VEJ	Heat shock protein
HRD54_RS17645	ENOG4105DQY	intracellular growth attenuator
HRD54_RS17650	ENOG4107RK2	ADP-ribose diphosphatase NudE
HRD54_RS17655	ENOG4105D01	(LipO)protein
HRD54_RS17660	ENOG4108JQC	penicillin-binding protein 1A
HRD54_RS17680	ENOG4105E4G	Type IV pilus
HRD54_RS17685	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRD54_RS17690	ENOG4105D49	3-dehydroquinate synthase
HRD54_RS17705	ENOG4105DJV	ribulose-phosphate 3-epimerase
HRD54_RS17710	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HRD54_RS17715	ENOG4105C31	Tryptophanyl-tRNA synthetase
HRD54_RS17720	ENOG4108RPX	mosc domain containing protein
HRD54_RS17725	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRD54_RS17730	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HRD54_RS17735	ENOG41062QD	Membrane
HRD54_RS17740	ENOG4107QN1	sodium solute
HRD54_RS17745	ENOG4105DIJ	Phosphoethanolamine transferase
HRD54_RS17750	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HRD54_RS17755	ENOG4107QR9	Iron-sulfur cluster binding protein
HRD54_RS17760	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HRD54_RS17785	ENOG4107EJG	GntR family transcriptional regulator
HRD54_RS17790	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD54_RS17795	ENOG4108RVA	ribokinase
HRD54_RS17800	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
HRD54_RS17805	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HRD54_RS17810	ENOG4105CU9	asparagine synthetase A
HRD54_RS17815	ENOG4108VVK	transcriptional Regulator, AsnC
HRD54_RS17820	ENOG4105QTB	Flavodoxin
HRD54_RS17825	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HRD54_RS17830	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HRD54_RS17835	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
HRD54_RS17840	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HRD54_RS17845	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD54_RS17850	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD54_RS17855	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD54_RS17860	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HRD54_RS17865	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HRD54_RS17870	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HRD54_RS17875	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HRD54_RS17880	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HRD54_RS17885	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HRD54_RS17890	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD54_RS17900	ENOG4105C4Y	ABC transporter
HRD54_RS17905	ENOG41080HI	glycine oxidase
HRD54_RS17920	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HRD54_RS17965	ENOG4105E6S	usher protein(
HRD54_RS17990	ENOG4105H4F	exported protein
HRD54_RS18000	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HRD54_RS18010	ENOG4107QZ7	Cellulose synthase catalytic subunit
HRD54_RS18020	ENOG4105EJG	cellulose synthase
HRD54_RS18030	ENOG4105BZU	Histidine kinase
HRD54_RS18035	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRD54_RS18040	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HRD54_RS18045	ENOG4107T7U	Sulfatase
HRD54_RS18050	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HRD54_RS18055	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HRD54_RS18060	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HRD54_RS18065	ENOG4108MG3	formate dehydrogenase
HRD54_RS18070	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD54_RS18080	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HRD54_RS18100	ENOG4106P55	Transcriptional regulator
HRD54_RS18120	ENOG41067XB	TonB family
HRD54_RS18135	ENOG4108UQ5	membrane protein YcdZ
HRD54_RS18140	ENOG4105CAF	HipA N-terminal domain protein
HRD54_RS18160	ENOG4108BUD	transposase
HRD54_RS18215	ENOG4107QKA	exodeoxyribonuclease V beta
HRD54_RS18285	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD54_RS18290	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HRD54_RS18295	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HRD54_RS18300	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HRD54_RS18305	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HRD54_RS18310	ENOG4105VG0	50S ribosomal protein l34
HRD54_RS18460	ENOG4105KT5	UmuD protein
HRD54_RS18465	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HRD54_RS18475	ENOG4108UUM	single-stranded DNA-binding protein
HRD54_RS18490	ENOG4105GMB	type VI secretion system effector, hcp1 family
HRD54_RS18515	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
HRD54_RS18520	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
HRD54_RS18580	ENOG4108BUD	transposase
HRD54_RS18600	ENOG4108BUD	transposase
HRD54_RS18620	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HRD54_RS18625	ENOG4105EPC	oxidoreductase
HRD54_RS18630	ENOG4105VF7	tolerance protein
HRD54_RS18635	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HRD54_RS18660	ENOG4108BUD	transposase
HRD54_RS18725	ENOG4105C3F	Signal peptidase i