locus-tag	class	description
HPT03_RS00010	ENOG4105KNY	Microcompartments protein
HPT03_RS00015	ENOG4105C0A	alcohol dehydrogenase
HPT03_RS00030	ENOG4105C6N	Formate acetyltransferase
HPT03_RS00035	ENOG4105F1A	Pyruvate formate-lyase
HPT03_RS00040	ENOG4105KNY	Microcompartments protein
HPT03_RS00045	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
HPT03_RS00070	ENOG4105BZS	acriflavin resistance protein
HPT03_RS00085	ENOG4108Z4X	TRANSCRIPTIONal
HPT03_RS00105	ENOG4108RBT	type iii secretion
HPT03_RS00115	ENOG4105Y7Q	type iii secretion
HPT03_RS00125	ENOG41090HZ	type iii secretion
HPT03_RS00135	ENOG4108N8R	Invasion protein
HPT03_RS00140	ENOG4108HR8	type iii secretion
HPT03_RS00150	ENOG4108JIR	Flagellum-specific ATP synthase
HPT03_RS00170	ENOG41075IY	surface presentation of antigens protein SpaP
HPT03_RS00175	ENOG4105U07	type iii secretion
HPT03_RS00180	ENOG4108TN6	type iii secretion
HPT03_RS00185	ENOG4108M6W	surface presentation of antigens protein SpaS
HPT03_RS00190	ENOG4108Z19	type iii secretion
HPT03_RS00215	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HPT03_RS00220	ENOG4108BSC	Methyltransferase
HPT03_RS00225	ENOG4105E0A	ABC, transporter
HPT03_RS00230	ENOG4105EHG	Permease protein
HPT03_RS00235	ENOG4105S10	periplasmic binding protein
HPT03_RS00240	ENOG4105DIQ	Transcriptional regulator
HPT03_RS00245	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HPT03_RS00250	ENOG4105C6Z	Gluconate
HPT03_RS00270	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HPT03_RS00275	ENOG4108UR8	BAX protein
HPT03_RS00295	ENOG4105Y3E	Modulates RecA activity (By similarity)
HPT03_RS00300	ENOG4108M1A	Chitin-binding protein
HPT03_RS00305	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HPT03_RS00310	ENOG4108XNW	Transcriptional activatory protein CaiF
HPT03_RS00320	ENOG4106YT9	Enoyl-CoA hydratase
HPT03_RS00325	ENOG4105CEY	Amp-dependent synthetase and ligase
HPT03_RS00330	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPT03_RS00335	ENOG4105C1G	acyl-Coa dehydrogenase
HPT03_RS00355	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HPT03_RS00360	ENOG4105WQV	ferredoxin-like protein
HPT03_RS00365	ENOG4105C54	Major Facilitator superfamily
HPT03_RS00370	ENOG4105CEY	Amp-dependent synthetase and ligase
HPT03_RS00380	ENOG4105CIZ	coA-substrate-specific enzyme activase
HPT03_RS00390	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
HPT03_RS00395	ENOG4105CY2	Citrate transporter
HPT03_RS00400	ENOG4105C1G	acyl-Coa dehydrogenase
HPT03_RS00405	ENOG4105CV7	Electron transfer flavoprotein
HPT03_RS00410	ENOG4105C10	Electron transfer flavoprotein
HPT03_RS00415	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HPT03_RS00420	ENOG4105WQV	ferredoxin-like protein
HPT03_RS00425	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HPT03_RS00430	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HPT03_RS00445	ENOG4108V0P	LemA family
HPT03_RS00450	ENOG4105HA9	of methanol dehydrogenase type
HPT03_RS00470	ENOG4108SIC	Transcriptional regulator
HPT03_RS00475	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HPT03_RS00490	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HPT03_RS00495	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HPT03_RS00505	ENOG4108ZVF	(LipO)protein
HPT03_RS00545	ENOG4105CW0	outer membrane usher protein
HPT03_RS00555	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HPT03_RS00560	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HPT03_RS00565	ENOG4108YZG	isomerase
HPT03_RS00570	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HPT03_RS00575	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HPT03_RS00580	ENOG4107TDF	Formate hydrogenlyase subunit 4
HPT03_RS00585	ENOG4105D65	subunit l
HPT03_RS00590	ENOG4107WQX	hydrogenase 4 membrane subunit
HPT03_RS00595	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HPT03_RS00600	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPT03_RS00610	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HPT03_RS00615	ENOG4105I6X	formate hydrogenlyase maturation
HPT03_RS00620	ENOG4108MG9	hydrogenase 3 maturation protease
HPT03_RS00625	ENOG4105K64	Glycosyl transferase, family 2
HPT03_RS00640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS00660	ENOG41076CZ	activating enzyme
HPT03_RS00665	ENOG4105G0K	glycine radical enzyme YjjI family
HPT03_RS00670	ENOG41062Z9	Membrane
HPT03_RS00675	ENOG4105EAC	phosphoserine phosphatase
HPT03_RS00680	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HPT03_RS00685	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HPT03_RS00695	ENOG4105E93	esterase
HPT03_RS00705	ENOG4105EAM	Na Pi-cotransporter
HPT03_RS00720	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HPT03_RS00730	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HPT03_RS00750	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HPT03_RS00795	ENOG4105KT5	UmuD protein
HPT03_RS00845	ENOG4105ESI	atpase involved in dna repair
HPT03_RS00915	ENOG4105T95	Thiol disulfide interChange protein
HPT03_RS00955	ENOG410890F	Dynamin family
HPT03_RS00965	ENOG4105RWS	endonuclease I
HPT03_RS00980	ENOG4108UUM	single-stranded DNA-binding protein
HPT03_RS01000	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
HPT03_RS01025	ENOG4108YGG	dna repair protein
HPT03_RS01045	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HPT03_RS01110	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HPT03_RS01120	ENOG4108NRW	Phospholipase, patatin family
HPT03_RS01125	ENOG4105EYA	deoxyribonuclease
HPT03_RS01130	ENOG4105D9N	nucleoside
HPT03_RS01135	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HPT03_RS01140	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HPT03_RS01145	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HPT03_RS01150	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HPT03_RS01155	ENOG4105D4T	Citrate transporter
HPT03_RS01165	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HPT03_RS01170	ENOG4105CA9	Pyruvate kinase
HPT03_RS01175	ENOG4105CXY	transporter
HPT03_RS01190	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
HPT03_RS01200	ENOG4106PG1	outer membrane usher protein
HPT03_RS01205	ENOG4108FZ9	Chaperone
HPT03_RS01210	ENOG4105UGQ	Fimbrial
HPT03_RS01230	ENOG4105VDH	Dihydroxyacetone kinase
HPT03_RS01235	ENOG4108UTZ	Dihydroxyacetone kinase
HPT03_RS01240	ENOG4105CMT	Dihydroxyacetone kinase
HPT03_RS01290	ENOG4105DAX	Pfam:DUF2983
HPT03_RS01340	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS01345	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS01350	ENOG4105DUM	transcriptional regulator, lysR family
HPT03_RS01355	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HPT03_RS01360	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPT03_RS01365	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HPT03_RS01375	ENOG4105FFC	UPF0187 protein
HPT03_RS01395	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPT03_RS01400	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HPT03_RS01410	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPT03_RS01415	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HPT03_RS01435	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HPT03_RS01440	ENOG4107ZVW	dihydroneopterin aldolase
HPT03_RS01445	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPT03_RS01450	ENOG4106MWK	domain protein
HPT03_RS01455	ENOG4105I7R	Adenylate cyclase
HPT03_RS01460	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HPT03_RS01465	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPT03_RS01480	ENOG4105W0Z	cytoplasmic protein
HPT03_RS01485	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HPT03_RS01490	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HPT03_RS01495	ENOG4106032	Glutathionylspermidine synthase
HPT03_RS01500	ENOG4105F1G	UPF0441 protein
HPT03_RS01505	ENOG4105DFG	type I secretion outer membrane protein
HPT03_RS01510	ENOG41087AY	ADP-Ribose pyrophosphatase
HPT03_RS01515	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HPT03_RS01520	ENOG4105IPS	esterase
HPT03_RS01525	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPT03_RS01530	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPT03_RS01535	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HPT03_RS01540	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HPT03_RS01555	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HPT03_RS01560	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HPT03_RS01565	ENOG4105NWN	ApaG protein
HPT03_RS01570	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HPT03_RS01575	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HPT03_RS01580	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPT03_RS01585	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HPT03_RS01590	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HPT03_RS01595	ENOG4105D3G	Pseudouridine synthase
HPT03_RS01600	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HPT03_RS01605	ENOG4105CQ2	DNA polymerase
HPT03_RS01615	ENOG4105VT3	DNA binding domain protein, excisionase family
HPT03_RS01620	ENOG4107T0D	ABC, transporter
HPT03_RS01625	ENOG4106SMU	thiamine transporter membrane protein
HPT03_RS01630	ENOG4105DP9	ABC transporter
HPT03_RS01635	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HPT03_RS01640	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HPT03_RS01645	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HPT03_RS01650	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HPT03_RS01685	ENOG4105DSY	exodeoxyribonuclease V, gamma
HPT03_RS01690	ENOG4107QXK	peptidase
HPT03_RS01695	ENOG4107QKA	exodeoxyribonuclease V beta
HPT03_RS01700	ENOG4107QYX	exodeoxyribonuclease v alpha
HPT03_RS01705	ENOG4107QZM	n-acetylglutamate synthase
HPT03_RS01710	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HPT03_RS01730	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HPT03_RS01735	ENOG4105CUZ	uba thif-type nad fad binding protein
HPT03_RS01740	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HPT03_RS01745	ENOG4105C9B	Cysteine desulfurase
HPT03_RS01750	ENOG4105ETT	transcriptional Regulator, LysR family
HPT03_RS01755	ENOG4105M08	Membrane
HPT03_RS01760	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HPT03_RS01765	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HPT03_RS01770	ENOG4105EWT	decarboxylase family
HPT03_RS01775	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HPT03_RS01780	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HPT03_RS01785	ENOG4105WP7	tRNA pseudouridine synthase C
HPT03_RS01790	ENOG4105DR9	pseudouridine synthase
HPT03_RS01795	ENOG4105CI1	PTS System
HPT03_RS01805	ENOG4105QDK	Flavodoxin
HPT03_RS01810	ENOG4108T8E	UPF0325 protein
HPT03_RS01815	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HPT03_RS01820	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HPT03_RS01825	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HPT03_RS01830	ENOG4105CE9	30S ribosomal protein S2
HPT03_RS01835	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HPT03_RS01840	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HPT03_RS01845	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HPT03_RS01850	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HPT03_RS01855	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HPT03_RS01860	ENOG4105KNE	Phosphatidate cytidylyltransferase
HPT03_RS01870	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPT03_RS01875	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HPT03_RS01880	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPT03_RS01885	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HPT03_RS01890	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPT03_RS01895	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPT03_RS01900	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPT03_RS01905	ENOG4105C0B	DNA polymerase III (alpha subunit)
HPT03_RS01910	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HPT03_RS01915	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HPT03_RS01920	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HPT03_RS01925	ENOG4105M1T	rho-binding antiterminator
HPT03_RS01930	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HPT03_RS01935	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HPT03_RS01940	ENOG4108R96	Methyltransferase, YaeB family
HPT03_RS01950	ENOG4105D01	(LipO)protein
HPT03_RS01955	ENOG4108UMI	ABC transporter, permease
HPT03_RS01960	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS01965	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HPT03_RS02015	ENOG4105C85	amino acid
HPT03_RS02020	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HPT03_RS02025	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HPT03_RS02030	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HPT03_RS02035	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HPT03_RS02040	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HPT03_RS02045	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HPT03_RS02050	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HPT03_RS02055	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HPT03_RS02060	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HPT03_RS02065	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HPT03_RS02070	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HPT03_RS02075	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HPT03_RS02080	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HPT03_RS02085	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HPT03_RS02090	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HPT03_RS02095	ENOG4108K5P	(LipO)protein
HPT03_RS02105	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HPT03_RS02120	ENOG4105K5X	acetyltransferase
HPT03_RS02125	ENOG4105CID	antiterminator
HPT03_RS02130	ENOG4105C5Y	PTS System
HPT03_RS02135	ENOG4105DB7	PHP domain protein
HPT03_RS02145	ENOG4105HMV	Fimbrial protein
HPT03_RS02155	ENOG4106PG1	outer membrane usher protein
HPT03_RS02160	ENOG4106P2F	Pfam:Pili_assembly_C
HPT03_RS02170	ENOG4106CXJ	Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 sp P42190 PAPK_ECOLI PROTEIN PAPK PRECURSOR
HPT03_RS02190	ENOG4106EAR	Fimbrial protein
HPT03_RS02200	ENOG4105CW0	outer membrane usher protein
HPT03_RS02230	ENOG4107QPK	)-transporter
HPT03_RS02240	ENOG4105EUB	pirin domain protein
HPT03_RS02245	ENOG4105CHJ	isochorismatase hydrolase
HPT03_RS02250	ENOG4107R1Q	Membrane protein FdrA
HPT03_RS02255	ENOG4107REC	cytoplasmic protein
HPT03_RS02260	ENOG4105G5A	Protein of unknown function (DUF2877)
HPT03_RS02265	ENOG4105C5B	carbamate kinase
HPT03_RS02275	ENOG4107653	Transcriptional regulator
HPT03_RS02285	ENOG4108HPI	phosphatidate Cytidylyltransferase
HPT03_RS02300	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HPT03_RS02305	ENOG4106NDP	Transcriptional regulator
HPT03_RS02310	ENOG4108HKT	sucrose-6-phosphate hydrolase
HPT03_RS02315	ENOG4105D7K	pfkb domain protein
HPT03_RS02320	ENOG4105FR1	rard protein
HPT03_RS02325	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HPT03_RS02330	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HPT03_RS02335	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HPT03_RS02340	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPT03_RS02345	ENOG4108QY5	Ferric enterobactin transport protein
HPT03_RS02350	ENOG4107RE1	Inosine-guanosine kinase
HPT03_RS02355	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HPT03_RS02360	ENOG4108RS6	transposase
HPT03_RS02365	ENOG4105D7V	transposase
HPT03_RS02370	ENOG4105CGH	5'-nucleotidase
HPT03_RS02375	ENOG4108Z66	YbaK ebsC protein
HPT03_RS02380	ENOG4105MBR	gumn family
HPT03_RS02390	ENOG4105C59	p-type ATPase
HPT03_RS02395	ENOG4108Z6Z	Transcriptional regulator
HPT03_RS02405	ENOG4107QX8	SPFH domain, Band 7 family protein
HPT03_RS02410	ENOG4107QR8	Thioredoxin
HPT03_RS02415	ENOG4105E1F	short-chain dehydrogenase reductase
HPT03_RS02420	ENOG4108UJV	acyl-CoA thioesterase i
HPT03_RS02425	ENOG4108I0Y	(ABC) transporter
HPT03_RS02430	ENOG4105CV6	ABC transporter, permease
HPT03_RS02435	ENOG4105D64	Mechanosensitive ion channel
HPT03_RS02445	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HPT03_RS02450	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HPT03_RS02455	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HPT03_RS02460	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HPT03_RS02465	ENOG4105C8N	cysteinyl-tRNA synthetase
HPT03_RS02470	ENOG4105DE4	1-phosphofructokinase
HPT03_RS02475	ENOG4105WQ3	Rna-binding protein
HPT03_RS02480	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HPT03_RS02550	ENOG4105RHY	Pfam:UPF0157
HPT03_RS02560	ENOG4105KBH	arsR family transcriptional regulator
HPT03_RS02570	ENOG4107ZY0	Phenazine biosynthesis-like protein
HPT03_RS02575	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPT03_RS02585	ENOG4108UHU	Aldolase
HPT03_RS02590	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HPT03_RS02595	ENOG4105D2N	Aldolase
HPT03_RS02605	ENOG4105ENH	Sulfatase
HPT03_RS02610	ENOG4105C4X	radical SAM domain protein
HPT03_RS02615	ENOG4105E98	transcriptional regulator DeoR family
HPT03_RS02620	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HPT03_RS02625	ENOG4105E70	isomerase
HPT03_RS02630	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HPT03_RS02635	ENOG4105ETZ	PTS System
HPT03_RS02640	ENOG4105F3R	pts system mannose fructose sorbose family iid
HPT03_RS02645	ENOG4105DAS	pts system
HPT03_RS02650	ENOG4105CE4	GlcNAc 6-P deacetylase
HPT03_RS02660	ENOG4105CHR	reductase
HPT03_RS02690	ENOG4105CBG	Sulfatase
HPT03_RS02710	ENOG4105DS1	cytochrome b561
HPT03_RS02715	ENOG4108YYC	ycei family
HPT03_RS02720	ENOG4107QHE	Choloylglycine hydrolase
HPT03_RS02725	ENOG4107SVH	Potassium channel protein
HPT03_RS02740	ENOG4105BZG	amino acid carrier protein
HPT03_RS02750	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HPT03_RS02755	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HPT03_RS02765	ENOG4105CJW	magnesium transporter
HPT03_RS02770	ENOG4105GPY	SprT protein
HPT03_RS02775	ENOG41080HT	Transcriptional regulator, arsr family
HPT03_RS02790	ENOG4105EJG	cellulose synthase
HPT03_RS02795	ENOG4107EEX	Cellulose synthase regulator protein
HPT03_RS02800	ENOG4107QZ7	Cellulose synthase catalytic subunit
HPT03_RS02805	ENOG4105UTS	cellulose synthase operon protein YhjQ
HPT03_RS02815	ENOG4105D1V	cellulose synthase operon protein YhjU
HPT03_RS02820	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HPT03_RS02825	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HPT03_RS02830	ENOG4105CYW	agmatinase
HPT03_RS02835	ENOG4105CHR	reductase
HPT03_RS02845	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HPT03_RS02850	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HPT03_RS02855	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPT03_RS02860	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPT03_RS02865	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HPT03_RS02870	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPT03_RS02875	ENOG41064T2	transcriptional regulator, lysR family
HPT03_RS02880	ENOG4108IQE	Amp-dependent synthetase and ligase
HPT03_RS02885	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HPT03_RS02890	ENOG4108V6E	Cell division protein mraZ
HPT03_RS02895	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HPT03_RS02900	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HPT03_RS02905	ENOG4105CJN	penicillin-binding protein
HPT03_RS02910	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HPT03_RS02915	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HPT03_RS02920	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HPT03_RS02930	ENOG4105CNI	cell division protein FtsW
HPT03_RS02935	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HPT03_RS02940	ENOG4105DFU	Cell wall formation (By similarity)
HPT03_RS02950	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HPT03_RS02955	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HPT03_RS02960	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HPT03_RS02965	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPT03_RS02975	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
HPT03_RS02980	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HPT03_RS02985	ENOG4106IWJ	hemolysin
HPT03_RS02990	ENOG4108I4D	hemolysin
HPT03_RS03000	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HPT03_RS03005	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HPT03_RS03010	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HPT03_RS03020	ENOG4107QHF	type ii secretion system protein e
HPT03_RS03025	ENOG4108ZUW	Major pilin subunit
HPT03_RS03030	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HPT03_RS03035	ENOG41073TP	transcriptional regulator
HPT03_RS03040	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HPT03_RS03045	ENOG4107QSN	dihydrolipoamide acetyltransferase
HPT03_RS03050	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPT03_RS03055	ENOG4105EUK	rtx toxin RtxA
HPT03_RS03070	ENOG4107QIJ	Aconitate hydratase 2
HPT03_RS03075	ENOG4108ZIG	UPF0231 protein
HPT03_RS03080	ENOG4105D64	Mechanosensitive ion channel
HPT03_RS03085	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HPT03_RS03090	ENOG4105MPN	Membrane
HPT03_RS03105	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HPT03_RS03110	ENOG4105E66	phosphoriboisomerase A
HPT03_RS03115	ENOG4108JQ1	Dehydrogenase
HPT03_RS03120	ENOG4108JJA	ABC, transporter
HPT03_RS03125	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HPT03_RS03135	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HPT03_RS03145	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HPT03_RS03150	ENOG4105E07	UPF0149 protein
HPT03_RS03155	ENOG4107RAQ	aminopeptidase
HPT03_RS03160	ENOG4105D0A	hydroxylase
HPT03_RS03165	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HPT03_RS03170	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPT03_RS03175	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HPT03_RS03180	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPT03_RS03190	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HPT03_RS03195	ENOG4105Y75	tpr repeat protein
HPT03_RS03205	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HPT03_RS03210	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HPT03_RS03215	ENOG4105T95	Thiol disulfide interChange protein
HPT03_RS03220	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HPT03_RS03230	ENOG4105CRK	lysyL-tRNA synthetase
HPT03_RS03280	ENOG4108YYQ	gCN5-related N-acetyltransferase
HPT03_RS03285	ENOG4105VXR	cytoplasmic protein
HPT03_RS03295	ENOG4105VVZ	metal-binding protein
HPT03_RS03300	ENOG4105Z2P	Protein of unknown function (DUF465)
HPT03_RS03305	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
HPT03_RS03310	ENOG4108RW8	Universal stress protein F
HPT03_RS03325	ENOG4105CMR	udp-glucose 4-epimerase
HPT03_RS03330	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HPT03_RS03335	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HPT03_RS03340	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HPT03_RS03345	ENOG41060NJ	transcriptional regulator
HPT03_RS03355	ENOG4105D05	Receptor
HPT03_RS03360	ENOG4105NIV	Esterase
HPT03_RS03370	ENOG4108XC3	NADH ubiquinone oxidoreductase
HPT03_RS03375	ENOG4105PI0	Ferredoxin
HPT03_RS03390	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HPT03_RS03395	ENOG4107QR9	Iron-sulfur cluster binding protein
HPT03_RS03400	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HPT03_RS03410	ENOG4105NF4	modulator of drug activity
HPT03_RS03425	ENOG4105DWT	malate dehydrogenase (quinone)
HPT03_RS03490	ENOG4105CVR	type I restriction-modification system
HPT03_RS03495	ENOG4105EKX	Restriction modification system DNA (Specificity
HPT03_RS03500	ENOG4105DZR	Type I site-specific deoxyribonuclease
HPT03_RS03520	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HPT03_RS03525	ENOG4108Z1B	Cyclase dehydrase
HPT03_RS03530	ENOG4105VDB	UPF0125 protein
HPT03_RS03535	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HPT03_RS03540	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HPT03_RS03545	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HPT03_RS03550	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPT03_RS03555	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HPT03_RS03560	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HPT03_RS03565	ENOG4105C1J	atp-dependent rna helicase
HPT03_RS03570	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HPT03_RS03575	ENOG4105EMN	RNA polymerase sigma factor
HPT03_RS03580	ENOG41069PW	sigma-e factor negative regulatory protein
HPT03_RS03585	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HPT03_RS03590	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HPT03_RS03595	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HPT03_RS03600	ENOG4105C3F	Signal peptidase i
HPT03_RS03605	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HPT03_RS03610	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HPT03_RS03615	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HPT03_RS03620	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HPT03_RS03625	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HPT03_RS03630	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HPT03_RS03635	ENOG4108Z6B	deaminase
HPT03_RS03640	ENOG4108YUF	Fimbrial
HPT03_RS03645	ENOG4108MDY	Fimbrial
HPT03_RS03650	ENOG4108FZ9	Chaperone
HPT03_RS03655	ENOG4106PG1	outer membrane usher protein
HPT03_RS03660	ENOG4108TH4	Major fimbrial subunit
HPT03_RS03665	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HPT03_RS03670	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HPT03_RS03675	ENOG4107WP9	Histidine kinase
HPT03_RS03680	ENOG4108SKK	alpha helix protein
HPT03_RS03685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPT03_RS03690	ENOG4105C4K	Nad synthetase
HPT03_RS03695	ENOG4108YZA	Nitrogen regulatory protein pii
HPT03_RS03705	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HPT03_RS03710	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HPT03_RS03715	ENOG4105D8G	Major Facilitator superfamily
HPT03_RS03730	ENOG4105ECY	inositol monophosphatase
HPT03_RS03735	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HPT03_RS03740	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HPT03_RS03745	ENOG4105C3J	Cysteine desulfurase
HPT03_RS03750	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HPT03_RS03755	ENOG4108Z4V	iron-sulfur cluster assembly
HPT03_RS03760	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HPT03_RS03765	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HPT03_RS03770	ENOG4108ZIT	Ferredoxin, 2FE-2S
HPT03_RS03775	ENOG4105WVQ	Fe-S assembly protein IscX
HPT03_RS03780	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HPT03_RS03785	ENOG4105YYA	enhanced serine sensitivity protein SseB
HPT03_RS03790	ENOG4105DN3	alpha-2-macroglobulin domain protein
HPT03_RS03795	ENOG4108JQB	penicillin-binding protein 1C
HPT03_RS03800	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HPT03_RS03805	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPT03_RS03815	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HPT03_RS03820	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HPT03_RS03825	ENOG4105CUT	histidyl-tRNA synthetase
HPT03_RS03830	ENOG4105N21	Membrane
HPT03_RS03835	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HPT03_RS03840	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HPT03_RS03850	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HPT03_RS03855	ENOG4108R6G	acetyltransferase
HPT03_RS03860	ENOG4105E7K	(LipO)protein
HPT03_RS03865	ENOG4105EZR	dyp-type peroxidase family protein
HPT03_RS03870	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HPT03_RS03875	ENOG4108I5D	sulfate abc transporter
HPT03_RS03880	ENOG4105ECW	sulfate abc transporter
HPT03_RS03885	ENOG4108IJ6	ABC transporter
HPT03_RS03890	ENOG4105C6T	cysteine synthase
HPT03_RS03895	ENOG4105C5Y	PTS System
HPT03_RS03900	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HPT03_RS03910	ENOG4105C6T	cysteine synthase
HPT03_RS03915	ENOG4105EXN	Sulfate transport protein CysZ
HPT03_RS03920	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HPT03_RS03925	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HPT03_RS03930	ENOG4105D9N	nucleoside
HPT03_RS03935	ENOG4105VRT	cytoplasmic protein
HPT03_RS03945	ENOG4105CHR	reductase
HPT03_RS03960	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HPT03_RS04000	ENOG4105ZUU	Transcriptional regulator
HPT03_RS04005	ENOG4108NWD	Cytochrome
HPT03_RS04010	ENOG4105QAX	Iron-sulfur
HPT03_RS04015	ENOG4108J2R	molybdopterin oxidoreductase
HPT03_RS04080	ENOG4108UUM	single-stranded DNA-binding protein
HPT03_RS04090	ENOG4108PNI	recT protein
HPT03_RS04095	ENOG41076J9	exonuclease VIII
HPT03_RS04170	ENOG4105CDU	Replicative dna helicase
HPT03_RS04205	ENOG4108V2F	protein ybcN in lambdoid DLP12 prophage regi
HPT03_RS04365	ENOG41067QW	Transcriptional regulator
HPT03_RS04415	ENOG4108TGC	Acyltransferase
HPT03_RS04430	ENOG410903C	(LipO)protein
HPT03_RS04435	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HPT03_RS04440	ENOG4105KZW	UPF0381 protein
HPT03_RS04445	ENOG4105CHU	acetyl-coa acetyltransferase
HPT03_RS04450	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPT03_RS04455	ENOG4108BY2	phosphohistidine phosphatase
HPT03_RS04460	ENOG4108DG9	Smr protein MutS2
HPT03_RS04470	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HPT03_RS04475	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HPT03_RS04480	ENOG4105EJ9	Membrane
HPT03_RS04485	ENOG4108BPE	-transporting atpase
HPT03_RS04490	ENOG4105MH2	YfcL protein
HPT03_RS04500	ENOG4105XYF	acetyltransferase
HPT03_RS04505	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HPT03_RS04510	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HPT03_RS04515	ENOG410631K	Membrane
HPT03_RS04520	ENOG4105Z68	AraC Family Transcriptional Regulator
HPT03_RS04525	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HPT03_RS04530	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HPT03_RS04535	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HPT03_RS04540	ENOG4105DQR	SNARE associated Golgi
HPT03_RS04545	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HPT03_RS04550	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HPT03_RS04555	ENOG4108S3P	Sporulation domain protein
HPT03_RS04560	ENOG4105E96	Colicin v production protein
HPT03_RS04565	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HPT03_RS04570	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPT03_RS04575	ENOG4105ECP	epimerase
HPT03_RS04580	ENOG4105CYM	Glutathione S-transferase
HPT03_RS04585	ENOG4105PTV	Nudix Hydrolase
HPT03_RS04595	ENOG4106ETB	IIa component
HPT03_RS04605	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HPT03_RS04610	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPT03_RS04615	ENOG4105DZG	Dehydrogenase
HPT03_RS04640	ENOG4105C6K	Malic enzyme
HPT03_RS04645	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HPT03_RS04650	ENOG4105PQ6	UPF0208 membrane protein
HPT03_RS04655	ENOG4105XWI	UPF0304 protein
HPT03_RS04660	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HPT03_RS04665	ENOG4107QWE	)-transporter
HPT03_RS04670	ENOG4105DK2	UPF0207 protein
HPT03_RS04675	ENOG4105CHM	Aminotransferase
HPT03_RS04680	ENOG4107NQ8	LysR family Transcriptional regulator
HPT03_RS04685	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPT03_RS04690	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPT03_RS04695	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPT03_RS04700	ENOG4105GKE	subunit e
HPT03_RS04705	ENOG4107QIZ	NADH dehydrogenase
HPT03_RS04710	ENOG4108IEH	NADH dehydrogenase subunit g
HPT03_RS04715	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HPT03_RS04720	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPT03_RS04725	ENOG4107UFS	subunit j
HPT03_RS04730	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPT03_RS04735	ENOG4105D65	subunit l
HPT03_RS04740	ENOG4105C8S	subunit m
HPT03_RS04745	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPT03_RS04750	ENOG4105GMB	type VI secretion system effector, hcp1 family
HPT03_RS04770	ENOG4105E4F	Isochorismate synthase
HPT03_RS04775	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HPT03_RS04780	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HPT03_RS04785	ENOG4108IPT	Naphthoate synthase
HPT03_RS04790	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HPT03_RS04795	ENOG4105CEY	Amp-dependent synthetase and ligase
HPT03_RS04800	ENOG4105CH6	catalase
HPT03_RS04805	ENOG4108UII	YfaZ family
HPT03_RS04810	ENOG4105E0U	tyrosine-specific transport protein
HPT03_RS04815	ENOG4105M5B	(LipO)protein
HPT03_RS04820	ENOG4105XPH	Ferredoxin
HPT03_RS04825	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HPT03_RS04830	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HPT03_RS04835	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HPT03_RS04840	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPT03_RS04845	ENOG4105BZU	Histidine kinase
HPT03_RS04850	ENOG41068CG	regulatoR
HPT03_RS04855	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
HPT03_RS04995	ENOG4107KGK	dmso reductase anchor subunit
HPT03_RS05000	ENOG4105QAX	Iron-sulfur
HPT03_RS05005	ENOG4107QY8	reductase
HPT03_RS05010	ENOG4105CUY	Mechanosensitive ion channel
HPT03_RS05015	ENOG4108YK4	Acid-resistance membrane protein
HPT03_RS05020	ENOG4105F0I	Aminotransferase
HPT03_RS05025	ENOG4105WBV	Transcriptional regulator
HPT03_RS05030	ENOG4108UMN	azlc family
HPT03_RS05055	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HPT03_RS05075	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HPT03_RS05080	ENOG4105DUX	Transporter
HPT03_RS05085	ENOG4105C6X	Major Facilitator
HPT03_RS05090	ENOG4105D1S	lipid A biosynthesis
HPT03_RS05095	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HPT03_RS05100	ENOG4106AFQ	Histidine kinase
HPT03_RS05105	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HPT03_RS05110	ENOG4106WHD	Tetrathionate reductase
HPT03_RS05115	ENOG4105DB1	molybdopterin oxidoreductase
HPT03_RS05125	ENOG4105PVA	Biofilm formation regulatory protein BssS
HPT03_RS05130	ENOG4105EKE	dihydroorotase
HPT03_RS05155	ENOG4105GSJ	Inner membrane protein ylaC
HPT03_RS05170	ENOG4105KT7	mgtC SapB transporter
HPT03_RS05175	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HPT03_RS05180	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HPT03_RS05185	ENOG4107RD7	Flagellar Motor Protein, MotA
HPT03_RS05190	ENOG4105ER2	Ompa motb domain protein
HPT03_RS05195	ENOG4105CBS	Chea signal transduction histidine kinase
HPT03_RS05200	ENOG4108V3W	Chemotaxis protein, CheW
HPT03_RS05205	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS05210	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS05215	ENOG4105BZU	Histidine kinase
HPT03_RS05220	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HPT03_RS05225	ENOG4108VYJ	response regulator receiver protein
HPT03_RS05230	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HPT03_RS05240	ENOG4105D00	flagellar biosynthetic protein flhB
HPT03_RS05245	ENOG4105D7B	Flagellar biosynthesis protein flha
HPT03_RS05250	ENOG4105CKT	filamentous hemagglutinin
HPT03_RS05255	ENOG4105QVD	Flagella synthesis protein FlgN
HPT03_RS05260	ENOG4105M9M	anti-sigma28 factor FlgM
HPT03_RS05265	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HPT03_RS05270	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HPT03_RS05275	ENOG4108ZC9	flagellar basal-body rod protein flgc
HPT03_RS05280	ENOG4105W00	Flagellar hook capping protein
HPT03_RS05285	ENOG4105BZE	flagellar hook protein, FlgE
HPT03_RS05290	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HPT03_RS05295	ENOG4105CGA	flagellar basal-body rod protein FlgG
HPT03_RS05300	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HPT03_RS05305	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HPT03_RS05310	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HPT03_RS05315	ENOG4105E1Q	flagellar hook-associated protein
HPT03_RS05320	ENOG4105DTJ	flagellar hook-associated protein
HPT03_RS05325	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HPT03_RS05335	ENOG4105CN7	Flagellar biosynthetic protein FliP
HPT03_RS05340	ENOG4105K0P	flagellar biosynthesis protein
HPT03_RS05345	ENOG4105DD5	Flagellar motor switch protein
HPT03_RS05350	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HPT03_RS05355	ENOG4107ZI8	flagellar basal body-associated protein flil
HPT03_RS05360	ENOG4105WF4	Flagellar hook-length control protein
HPT03_RS05365	ENOG4105GSA	Flagellar export protein flij
HPT03_RS05370	ENOG4108JIR	Flagellum-specific ATP synthase
HPT03_RS05375	ENOG41090PJ	Flagellar assembly protein
HPT03_RS05380	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HPT03_RS05385	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HPT03_RS05390	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HPT03_RS05415	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
HPT03_RS05420	ENOG4105MQ3	flagellar protein FliS
HPT03_RS05425	ENOG4105DTS	flagellar hook-associated
HPT03_RS05435	ENOG4105I03	Flagellin
HPT03_RS05440	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPT03_RS05445	ENOG4108M9K	flagella biosynthesis protein FliZ
HPT03_RS05450	ENOG4105C26	Dehydrogenase
HPT03_RS05455	ENOG4105CK7	Sodium proline symporter
HPT03_RS05465	ENOG4105C85	amino acid
HPT03_RS05470	ENOG4108U51	Universal stress protein
HPT03_RS05480	ENOG41081QV	Universal stress protein
HPT03_RS05485	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HPT03_RS05490	ENOG4105DHI	Methyltransferase
HPT03_RS05495	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HPT03_RS05500	ENOG4105EJQ	L-serine dehydratase
HPT03_RS05505	ENOG4105P8F	nudix hydrolase
HPT03_RS05510	ENOG4105CRQ	synthase (Component I)
HPT03_RS05515	ENOG4105X5C	UPF0181 protein
HPT03_RS05525	ENOG4105MPK	DNA polymerase III subunit theta
HPT03_RS05530	ENOG4105BZG	amino acid carrier protein
HPT03_RS05535	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HPT03_RS05540	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HPT03_RS05545	ENOG410667J	hydrolase
HPT03_RS05550	ENOG4108W3Q	Transcriptional regulator
HPT03_RS05560	ENOG4105C85	amino acid
HPT03_RS05565	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
HPT03_RS05575	ENOG4105DWF	phosphomethylpyrimidine kinase
HPT03_RS05580	ENOG4105EIE	fructose-bisphosphate aldolase
HPT03_RS05585	ENOG4107TE5	Lipid kinase
HPT03_RS05590	ENOG4105CFP	Peptidase U32
HPT03_RS05595	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HPT03_RS05600	ENOG4105EB3	Histidine kinase
HPT03_RS05605	ENOG4105BZS	acriflavin resistance protein
HPT03_RS05610	ENOG4105BZS	acriflavin resistance protein
HPT03_RS05615	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HPT03_RS05620	ENOG4105DUX	Transporter
HPT03_RS05630	ENOG4105CSH	Transporter
HPT03_RS05640	ENOG4105CJW	magnesium transporter
HPT03_RS05645	ENOG4105C9X	ppx gppa phosphatase
HPT03_RS05650	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HPT03_RS05655	ENOG4108MK9	spermidine N(1)-acetyltransferase
HPT03_RS05660	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HPT03_RS05665	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HPT03_RS05670	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HPT03_RS05675	ENOG4105C2W	permease
HPT03_RS05680	ENOG4105CUY	Mechanosensitive ion channel
HPT03_RS05685	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HPT03_RS05690	ENOG4105EAA	nucleoside
HPT03_RS05695	ENOG4105K89	arsenate reductase
HPT03_RS05700	ENOG4105ERG	peptidase m48, ste24p
HPT03_RS05705	ENOG4105C02	permease
HPT03_RS05710	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPT03_RS05715	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HPT03_RS05720	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPT03_RS05725	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HPT03_RS05730	ENOG4105C8V	SAICAR synthetase
HPT03_RS05735	ENOG4105CGZ	zinc metallopeptidase
HPT03_RS05740	ENOG4108VMM	UPF0756 membrane protein
HPT03_RS05745	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HPT03_RS05750	ENOG4105XYK	UPF0370 protein
HPT03_RS05755	ENOG4105WD1	Membrane
HPT03_RS05765	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HPT03_RS05770	ENOG4105KUZ	arsenate reductase
HPT03_RS05780	ENOG4105WH1	Two component transcriptional regulator luxr family
HPT03_RS05785	ENOG4105C6K	Malic enzyme
HPT03_RS05800	ENOG4105CUG	Oligopeptidase b
HPT03_RS05810	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPT03_RS05815	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HPT03_RS05820	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPT03_RS05825	ENOG410756H	nucleotidyltransferase
HPT03_RS05840	ENOG4105VF7	tolerance protein
HPT03_RS05845	ENOG4105DKT	Transcriptional regulator
HPT03_RS05850	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
HPT03_RS05860	ENOG4108VEN	abc transporter atp-binding protein
HPT03_RS05885	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HPT03_RS05905	ENOG4108RVA	ribokinase
HPT03_RS05920	ENOG41080QX	K07048 phosphotriesterase-related protein
HPT03_RS05925	ENOG4105CBT	Fructose-1,6-bisphosphatase
HPT03_RS05935	ENOG4105WH1	Two component transcriptional regulator luxr family
HPT03_RS05940	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HPT03_RS05945	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HPT03_RS05975	ENOG41065CD	Exported protein
HPT03_RS05980	ENOG4105D7X	high-affinity nickel-transporter
HPT03_RS05995	ENOG4105F27	Major Facilitator
HPT03_RS06000	ENOG410814C	multidrug resistance protein
HPT03_RS06010	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HPT03_RS06015	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HPT03_RS06020	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
HPT03_RS06040	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPT03_RS06045	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPT03_RS06050	ENOG4105C8H	hydrogenase maturation protein Hypf
HPT03_RS06055	ENOG4105GNX	MltA-interacting MipA family protein
HPT03_RS06060	ENOG4105DSB	aldose 1-epimerase
HPT03_RS06070	ENOG4105E0X	reductase
HPT03_RS06075	ENOG4105VUT	cytoplasmic protein
HPT03_RS06080	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HPT03_RS06090	ENOG4108RWI	nicotinamidase
HPT03_RS06095	ENOG4105HDK	L-asparaginase
HPT03_RS06100	ENOG4105D07	Signal peptide peptidase, SppA
HPT03_RS06105	ENOG41069NU	Nitroreductase
HPT03_RS06110	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HPT03_RS06115	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HPT03_RS06120	ENOG4105CGK	Exodeoxyribonuclease III
HPT03_RS06125	ENOG4105ETT	transcriptional Regulator, LysR family
HPT03_RS06135	ENOG4105CIY	formyltetrahydrofolate deformylase
HPT03_RS06140	ENOG4105K5B	UPF0225 protein
HPT03_RS06145	ENOG4105I93	response regulator
HPT03_RS06150	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HPT03_RS06165	ENOG4107104	thymidine kinase
HPT03_RS06170	ENOG4105C0A	alcohol dehydrogenase
HPT03_RS06175	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HPT03_RS06180	ENOG4108JQ7	(ABC) transporter
HPT03_RS06190	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS06195	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS06205	ENOG4107QZF	nitrite reductase NADPH large subunit
HPT03_RS06210	ENOG4105WZK	nitrite reductase NADPH small subunit
HPT03_RS06220	ENOG4107QSI	ABC, transporter
HPT03_RS06225	ENOG4107QSI	ABC, transporter
HPT03_RS06230	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS06235	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS06240	ENOG4105C3U	ABC transporter
HPT03_RS06245	ENOG4108JQ7	(ABC) transporter
HPT03_RS06250	ENOG4105ZUU	Transcriptional regulator
HPT03_RS06255	ENOG4108WDE	Fimbrial protein
HPT03_RS06260	ENOG4108S54	Fimbrial protein
HPT03_RS06265	ENOG4108AF8	Chaperone
HPT03_RS06270	ENOG4105CW0	outer membrane usher protein
HPT03_RS06275	ENOG4108M66	Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity)
HPT03_RS06285	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HPT03_RS06290	ENOG4105C94	Transporter
HPT03_RS06295	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HPT03_RS06300	ENOG4105C26	Dehydrogenase
HPT03_RS06305	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HPT03_RS06310	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HPT03_RS06315	ENOG4105DZC	cytosine deaminase
HPT03_RS06325	ENOG4105D52	delta-aminolevulinic acid dehydratase
HPT03_RS06335	ENOG4105XVG	cytoplasmic protein
HPT03_RS06340	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HPT03_RS06345	ENOG4108U51	Universal stress protein
HPT03_RS06355	ENOG4108U51	Universal stress protein
HPT03_RS06360	ENOG410657R	replicase EC 2.7
HPT03_RS06380	ENOG4105DWK	Membrane
HPT03_RS06385	ENOG4107XM3	UPF0442 protein
HPT03_RS06395	ENOG4105RWS	endonuclease I
HPT03_RS06405	ENOG4105D5M	phosphate starvation-inducible protein
HPT03_RS06410	ENOG4105KAF	membrAne
HPT03_RS06425	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HPT03_RS06430	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPT03_RS06435	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPT03_RS06440	ENOG4105N14	lysine exporter protein LysE YggA
HPT03_RS06445	ENOG4105EW9	transcriptional regulator AsnC family
HPT03_RS06450	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS06455	ENOG4105EHG	Permease protein
HPT03_RS06460	ENOG4107R4I	Periplasmic binding protein
HPT03_RS06465	ENOG4106QJH	hemin transport protein
HPT03_RS06470	ENOG4107ENK	receptor
HPT03_RS06475	ENOG4107ENK	receptor
HPT03_RS06480	ENOG4107F3C	Hemin uptake protein
HPT03_RS06485	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HPT03_RS06490	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HPT03_RS06495	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HPT03_RS06500	ENOG4105IPI	Membrane
HPT03_RS06505	ENOG4105CQB	FAD linked oxidase domain protein
HPT03_RS06510	ENOG4105KA0	thioesterase Superfamily protein
HPT03_RS06520	ENOG4108Z4V	iron-sulfur cluster assembly
HPT03_RS06525	ENOG4105DIW	FeS assembly protein SUFB
HPT03_RS06530	ENOG4105C3K	feS assembly ATPase SufC
HPT03_RS06535	ENOG4105JRK	feS assembly protein SufD
HPT03_RS06540	ENOG4105C9B	Cysteine desulfurase
HPT03_RS06545	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HPT03_RS06550	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HPT03_RS06555	ENOG4105KMX	major outer membrane lipoprotein
HPT03_RS06565	ENOG4105CVK	Glutamate decarboxylase
HPT03_RS06570	ENOG4105E5D	amino acid
HPT03_RS06575	ENOG4105CA9	Pyruvate kinase
HPT03_RS06590	ENOG4107QI1	Mate efflux family protein
HPT03_RS06595	ENOG4108R6K	riboflavin synthase, subunit alpha
HPT03_RS06600	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPT03_RS06605	ENOG4105CZQ	inner membrane transport protein YdhC
HPT03_RS06610	ENOG4105F52	Transcriptional regulator
HPT03_RS06615	ENOG4105ETE	Transcriptional regulator (LacI family
HPT03_RS06625	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HPT03_RS06630	ENOG4105HF0	Membrane
HPT03_RS06645	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HPT03_RS06650	ENOG4105M2J	Glutaredoxin
HPT03_RS06655	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HPT03_RS06660	ENOG4108UYE	Lactoylglutathione lyase
HPT03_RS06665	ENOG4105XZD	Fe-S protein
HPT03_RS06675	ENOG4108XTF	Outer Membrane Lipoprotein
HPT03_RS06680	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HPT03_RS06685	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HPT03_RS06690	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HPT03_RS06695	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HPT03_RS06700	ENOG4108K3A	Glutathione S-transferase
HPT03_RS06705	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HPT03_RS06710	ENOG4108JQ2	peptide transport system atp-binding protein
HPT03_RS06715	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HPT03_RS06720	ENOG4108EU3	peptide transport system, permease
HPT03_RS06725	ENOG4108EKA	peptide transport system, permease
HPT03_RS06730	ENOG4108HIY	periplasmic
HPT03_RS06735	ENOG4105E51	psp operon transcriptional activator
HPT03_RS06740	ENOG41087YS	Phage shock protein A
HPT03_RS06745	ENOG4105YYT	phage shock protein B
HPT03_RS06750	ENOG4105FM1	phage shock protein C
HPT03_RS06760	ENOG4105CM6	amino acid regulated cytosolic protein
HPT03_RS06765	ENOG4106K28	UPF0283 membrane protein
HPT03_RS06780	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HPT03_RS06785	ENOG4107QSI	ABC, transporter
HPT03_RS06800	ENOG4107RX3	Mg2 transporter protein cora family protein
HPT03_RS06820	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HPT03_RS06825	ENOG4108T1M	outer membrane protein x
HPT03_RS06835	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HPT03_RS06850	ENOG4105NAU	thioesterase Superfamily protein
HPT03_RS06855	ENOG4107835	probably involved in intracellular septation (By similarity)
HPT03_RS06865	ENOG4108S3I	UPF0259 membrane protein
HPT03_RS06870	ENOG4105EIF	outer membrane protein W
HPT03_RS06880	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HPT03_RS06885	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HPT03_RS06890	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HPT03_RS06895	ENOG4107QYG	anthranilate phosphoribosyltransferase
HPT03_RS06900	ENOG4105DDQ	anthranilate synthase
HPT03_RS06905	ENOG4105CRQ	synthase (Component I)
HPT03_RS06910	ENOG4105DB7	PHP domain protein
HPT03_RS06915	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HPT03_RS06920	ENOG4105FE9	pseudouridine synthase
HPT03_RS06930	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HPT03_RS06935	ENOG4105UBK	short-chain dehydrogenase reductase
HPT03_RS06940	ENOG4105ERU	peptidase
HPT03_RS06945	ENOG4105RKX	Protein of unknown function (DUF2498)
HPT03_RS06950	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HPT03_RS06975	ENOG4107R11	Transcriptional regulator
HPT03_RS06985	ENOG4107QM5	aconitate hydratase
HPT03_RS06995	ENOG4105D01	(LipO)protein
HPT03_RS07000	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HPT03_RS07005	ENOG4105EYK	Phosphatidylglycerophosphatase B
HPT03_RS07010	ENOG4105Q4A	inner membrane protein yciS
HPT03_RS07015	ENOG4105CFV	Tetratricopeptide repeat protein
HPT03_RS07020	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HPT03_RS07025	ENOG4108ZJT	translation initiation factor, Sui1
HPT03_RS07030	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HPT03_RS07035	ENOG4105CSM	endonuclease III
HPT03_RS07045	ENOG4108UQQ	Electron transport complex
HPT03_RS07055	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HPT03_RS07065	ENOG4105DGN	Electron transport complex
HPT03_RS07070	ENOG4105M9B	inner membrane protein ydgK
HPT03_RS07075	ENOG4105D9R	oxidoreductase
HPT03_RS07080	ENOG4105DHU	Bile acid
HPT03_RS07085	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HPT03_RS07095	ENOG4106J39	exported protein
HPT03_RS07100	ENOG4105C9Q	fumarate hydratase class II
HPT03_RS07105	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
HPT03_RS07110	ENOG4105D94	Major Facilitator Superfamily
HPT03_RS07115	ENOG4106NZI	LysR family Transcriptional regulator
HPT03_RS07120	ENOG4105DAG	ROK family
HPT03_RS07125	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPT03_RS07135	ENOG4105M5Q	UPF0482 protein
HPT03_RS07140	ENOG4105EMU	Dehydrogenase
HPT03_RS07170	ENOG4105GMB	type VI secretion system effector, hcp1 family
HPT03_RS07195	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HPT03_RS07200	ENOG4105T16	Transcriptional regulator (AraC family)
HPT03_RS07210	ENOG4105DFD	Na H antiporter
HPT03_RS07215	ENOG4105C93	Xylose Isomerase
HPT03_RS07220	ENOG4105CMG	Carbohydrate kinase
HPT03_RS07235	ENOG4105C5W	Aldolase
HPT03_RS07240	ENOG4105R8A	Heat shock protein
HPT03_RS07250	ENOG4105DFG	type I secretion outer membrane protein
HPT03_RS07255	ENOG4108MI0	Resistance protein
HPT03_RS07260	ENOG4105J12	Multidrug resistance protein mdtN
HPT03_RS07270	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HPT03_RS07285	ENOG4105CNH	Multidrug resistance protein MdtL
HPT03_RS07295	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HPT03_RS07300	ENOG4108UPT	UPF0178 protein
HPT03_RS07305	ENOG4105C5H	ABC transporter
HPT03_RS07325	ENOG4105CBN	LysR family transcriptional regulator
HPT03_RS07330	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HPT03_RS07335	ENOG4105E5W	Transporter
HPT03_RS07355	ENOG4105D01	(LipO)protein
HPT03_RS07370	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HPT03_RS07375	ENOG4105CPF	Cell wall formation (By similarity)
HPT03_RS07380	ENOG4105C5H	ABC transporter
HPT03_RS07385	ENOG4105V0I	UPF0267 protein
HPT03_RS07390	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPT03_RS07415	ENOG4105KME	endoribonuclease L-psp
HPT03_RS07425	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPT03_RS07435	ENOG4105CMT	Dihydroxyacetone kinase
HPT03_RS07455	ENOG4105E98	transcriptional regulator DeoR family
HPT03_RS07460	ENOG4107QY8	reductase
HPT03_RS07465	ENOG4105QAX	Iron-sulfur
HPT03_RS07470	ENOG4107KGK	dmso reductase anchor subunit
HPT03_RS07475	ENOG4108NEM	leader-binding protein dmsD
HPT03_RS07480	ENOG4107Y2X	deaminase
HPT03_RS07485	ENOG4107SNB	ankyrin repeat protein YahD
HPT03_RS07490	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HPT03_RS07495	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HPT03_RS07500	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HPT03_RS07505	ENOG4105C08	Histidine kinase
HPT03_RS07510	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HPT03_RS07515	ENOG4105CMI	transporter
HPT03_RS07520	ENOG4105CJ1	ABC, transporter
HPT03_RS07525	ENOG4105D0S	secretion protein (HlyD
HPT03_RS07530	ENOG4105D44	asparaginase
HPT03_RS07535	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HPT03_RS07540	ENOG4105FYV	Amp nucleosidase
HPT03_RS07575	ENOG4105ZTC	transcriptional activator, Ogr delta
HPT03_RS07580	ENOG4108JU3	Alkyl hydroperoxide reductase
HPT03_RS07585	ENOG4105D3R	alkyl hydroperoxide reductase
HPT03_RS07600	ENOG4105NTW	Transcriptional regulator
HPT03_RS07625	ENOG4105QAX	Iron-sulfur
HPT03_RS07630	ENOG4107QY8	reductase
HPT03_RS07635	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HPT03_RS07640	ENOG4105Q9Y	Universal stress protein
HPT03_RS07645	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPT03_RS07650	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPT03_RS07655	ENOG4105C5D	exported protein
HPT03_RS07660	ENOG4105D5Q	Arginine ornithine antiporter
HPT03_RS07670	ENOG4108VCD	Chaperone
HPT03_RS07675	ENOG4105CW0	outer membrane usher protein
HPT03_RS07725	ENOG4105WXT	Conserved Protein
HPT03_RS07730	ENOG410689M	(LipO)protein
HPT03_RS07735	ENOG4107H52	Dicarboxylate transport
HPT03_RS07740	ENOG4105C5I	Dehydrogenase
HPT03_RS07745	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS07755	ENOG4105UEI	Transcriptional Regulator AraC Family
HPT03_RS07765	ENOG41083J0	(ABC) transporter
HPT03_RS07770	ENOG4105C4B	ABC transporter, permease
HPT03_RS07775	ENOG4108ZZ3	UPF0260 protein
HPT03_RS07780	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HPT03_RS07785	ENOG4105CVE	Lytic murein transglycosylase
HPT03_RS07790	ENOG4105VNG	YcgL domain-containing protein
HPT03_RS07795	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HPT03_RS07800	ENOG4107QMS	site-determining protein
HPT03_RS07805	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HPT03_RS07810	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HPT03_RS07815	ENOG4105CEY	Amp-dependent synthetase and ligase
HPT03_RS07820	ENOG4105Y4Z	Outer Membrane Lipoprotein
HPT03_RS07825	ENOG41072GX	Peptidase M22 Glycoprotease
HPT03_RS07830	ENOG4105DVT	helicase
HPT03_RS07835	ENOG4105M4H	endoribonuclease L-psp
HPT03_RS07840	ENOG4105CGD	Nad-dependent epimerase dehydratase
HPT03_RS07845	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
HPT03_RS07850	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HPT03_RS07855	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HPT03_RS07860	ENOG4106KNT	transcriptional regulator
HPT03_RS07865	ENOG4105CA9	Pyruvate kinase
HPT03_RS07870	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HPT03_RS07875	ENOG4105DR5	peptidase
HPT03_RS07880	ENOG4105NXV	High-affinity zinc uptake system protein
HPT03_RS07885	ENOG4105FDK	ABC transporter
HPT03_RS07890	ENOG4105FAV	ABC, transporter
HPT03_RS07995	ENOG4105DQ6	Transposase
HPT03_RS08005	ENOG4105GGE	ribonuclease
HPT03_RS08025	ENOG4105CNA	YD repeat protein
HPT03_RS08035	ENOG4105CS6	Rhs element vgr protein
HPT03_RS08040	ENOG4108WC9	type VI secretion system effector, hcp1 family
HPT03_RS08045	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HPT03_RS08050	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HPT03_RS08055	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HPT03_RS08060	ENOG4105CDY	transcriptional regulatory protein
HPT03_RS08065	ENOG4108TIT	dATP pyrophosphohydrolase
HPT03_RS08070	ENOG4105C9M	aspartyl-trna synthetase
HPT03_RS08075	ENOG4105WJG	Glutathione
HPT03_RS08080	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HPT03_RS08085	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HPT03_RS08090	ENOG4105C5H	ABC transporter
HPT03_RS08100	ENOG4106N3A	copper homeostasis protein cutc
HPT03_RS08105	ENOG4106ZCM	YecM protein
HPT03_RS08110	ENOG4105C75	arginyL-tRNA synthetase
HPT03_RS08120	ENOG4105CJR	Integral membrane protein (MviN
HPT03_RS08125	ENOG4105D9U	N-acetyltransferase
HPT03_RS08130	ENOG4105EV4	Multidrug resistance protein mdtH
HPT03_RS08140	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HPT03_RS08155	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HPT03_RS08165	ENOG4105CHH	sulfate transporter
HPT03_RS08175	ENOG4105N5T	Radical SAM Protein
HPT03_RS08180	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HPT03_RS08185	ENOG41063JG	Transcriptional regulator
HPT03_RS08190	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HPT03_RS08195	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HPT03_RS08200	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HPT03_RS08205	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HPT03_RS08210	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HPT03_RS08215	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HPT03_RS08220	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
HPT03_RS08225	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HPT03_RS08230	ENOG4105C3G	gtp-binding protein
HPT03_RS08265	ENOG4107TV1	YD repeat protein
HPT03_RS08325	ENOG4105C7K	acetolactate synthase
HPT03_RS08330	ENOG4107ZTW	SNARE associated Golgi
HPT03_RS08345	ENOG4107YCY	Transcriptional regulator
HPT03_RS08350	ENOG4105D5U	fad dependent oxidoreductase
HPT03_RS08360	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HPT03_RS08365	ENOG4108QBX	(LipO)protein
HPT03_RS08370	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HPT03_RS08375	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HPT03_RS08380	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPT03_RS08385	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPT03_RS08390	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPT03_RS08395	ENOG4105CKK	Glycosyl transferase, family 2
HPT03_RS08400	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HPT03_RS08405	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS08410	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HPT03_RS08415	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HPT03_RS08420	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HPT03_RS08425	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HPT03_RS08435	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HPT03_RS08440	ENOG41082NX	50s ribosomal protein l35
HPT03_RS08445	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HPT03_RS08450	ENOG4105C22	threonyL-tRNA synthetase
HPT03_RS08455	ENOG4106PIH	fimbrial-like protein ydeQ
HPT03_RS08465	ENOG4108Z7R	Chaperone CsaA
HPT03_RS08485	ENOG4105DSE	periplasmic solute binding protein
HPT03_RS08490	ENOG4105DIK	(ABC) transporter
HPT03_RS08495	ENOG4105CC5	ABC transporter
HPT03_RS08500	ENOG4105CC5	ABC transporter
HPT03_RS08510	ENOG4107PN8	YfeABCD locus regulator
HPT03_RS08515	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HPT03_RS08530	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HPT03_RS08535	ENOG4108ETY	sodium dicarboxylate symporter
HPT03_RS08540	ENOG4105D0M	Protease HtpX homolog
HPT03_RS08550	ENOG4105CN1	protease
HPT03_RS08555	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HPT03_RS08560	ENOG4108ZGC	gaf domain protein
HPT03_RS08565	ENOG4105H2K	paraquat-inducible protein a
HPT03_RS08570	ENOG4105DY2	Paraquat-inducible protein b
HPT03_RS08580	ENOG4105NKT	exported protein
HPT03_RS08585	ENOG4108PNC	copper resistance
HPT03_RS08590	ENOG4105FXM	Copper resistance protein
HPT03_RS08595	ENOG41090A1	ferritin
HPT03_RS08600	ENOG4108RW8	Universal stress protein F
HPT03_RS08615	ENOG4107SSZ	Phosphatase
HPT03_RS08620	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
HPT03_RS08630	ENOG4105HRS	Antitermination protein
HPT03_RS08635	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HPT03_RS08665	ENOG4105Z2P	Protein of unknown function (DUF465)
HPT03_RS08675	ENOG4107SEY	Conserved Protein
HPT03_RS08690	ENOG4108WF3	methyltransferase
HPT03_RS08695	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
HPT03_RS08700	ENOG4105GTN	ParB Domain Protein Nuclease
HPT03_RS08710	ENOG4105DBI	uridine monophosphokinase
HPT03_RS08720	ENOG4105ECR	NmrA family
HPT03_RS08725	ENOG4105KVH	Transcriptional regulator
HPT03_RS08735	ENOG4108ZNX	Heat shock protein
HPT03_RS08740	ENOG4105VEQ	Cold shock protein
HPT03_RS08770	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HPT03_RS08875	ENOG4105CAR	Terminase, large subunit
HPT03_RS08920	ENOG4105KUS	lysozyme
HPT03_RS08935	ENOG4105CQR	helicase
HPT03_RS08945	ENOG4108ZNX	Heat shock protein
HPT03_RS08950	ENOG4105VEQ	Cold shock protein
HPT03_RS08955	ENOG4105HRS	Antitermination protein
HPT03_RS08960	ENOG4108MXB	Protein of unknown function (DUF968)
HPT03_RS09005	ENOG4108R7K	Metal Dependent Phosphohydrolase
HPT03_RS09015	ENOG4108I1J	Integrase
HPT03_RS09020	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HPT03_RS09025	ENOG4108R99	pseudouridine synthase
HPT03_RS09035	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HPT03_RS09040	ENOG41075W9	High frequency lysogenization protein HflD homolog
HPT03_RS09045	ENOG4107QTF	adenylosuccinate lyase
HPT03_RS09050	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPT03_RS09055	ENOG4105IFJ	Histidine kinase
HPT03_RS09060	ENOG4105EZE	Cupin 4 family protein
HPT03_RS09075	ENOG4105D60	lipoprotein releasing system transmembrane protein
HPT03_RS09085	ENOG4105D60	lipoprotein releasing system transmembrane protein
HPT03_RS09090	ENOG4108JA2	transcriptioN-repair coupling factor
HPT03_RS09095	ENOG4107MBR	17 kDa surface antigen
HPT03_RS09100	ENOG4105CEP	NADH dehydrogenase
HPT03_RS09105	ENOG4105D0Y	UPF0227 protein
HPT03_RS09110	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HPT03_RS09115	ENOG4108KN0	Choline kinase
HPT03_RS09120	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
HPT03_RS09125	ENOG41090DQ	Lipoprotein
HPT03_RS09130	ENOG4105K59	histidine triad (HIT) protein
HPT03_RS09135	ENOG4105F8V	Hydrolase, tatD family
HPT03_RS09140	ENOG4107QRG	dna polymerase iii
HPT03_RS09145	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HPT03_RS09150	ENOG4105HHA	aminodeoxychorismate lyase
HPT03_RS09155	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HPT03_RS09160	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HPT03_RS09165	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HPT03_RS09170	ENOG4105CHR	reductase
HPT03_RS09175	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HPT03_RS09180	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPT03_RS09185	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HPT03_RS09190	ENOG4105VGS	50s ribosomal protein l32
HPT03_RS09195	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HPT03_RS09200	ENOG4108UHJ	MAF-like protein
HPT03_RS09210	ENOG4105EI2	Pseudouridine synthase
HPT03_RS09215	ENOG4107QQB	Ribonuclease E
HPT03_RS09220	ENOG41090HJ	UPF0265 protein
HPT03_RS09225	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
HPT03_RS09230	ENOG4105CJB	Exodeoxyribonuclease I
HPT03_RS09235	ENOG4105CXG	d-lactate dehydrogenase
HPT03_RS09240	ENOG4105C5Q	Transcriptional regulator
HPT03_RS09245	ENOG4107RA9	decarboxylase
HPT03_RS09255	ENOG4105CUB	amino acid
HPT03_RS09260	ENOG4105D05	Receptor
HPT03_RS09265	ENOG4108IQI	permease
HPT03_RS09270	ENOG4105DUM	transcriptional regulator, lysR family
HPT03_RS09275	ENOG4105HMI	Membrane
HPT03_RS09290	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HPT03_RS09305	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HPT03_RS09320	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HPT03_RS09325	ENOG4107TT5	NLP P60 protein
HPT03_RS09335	ENOG4105C2C	drug resistance transporter, Bcr CflA
HPT03_RS09340	ENOG4105I08	Pseudouridine synthase
HPT03_RS09345	ENOG4105CFI	type iii restriction protein res subunit
HPT03_RS09350	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HPT03_RS09355	ENOG4106V8H	Nucleoid-associated protein
HPT03_RS09360	ENOG4105PAN	UPF0352 protein
HPT03_RS09365	ENOG4105E68	Sulfatase
HPT03_RS09380	ENOG4107XU6	Glycosyl transferase (Group 1
HPT03_RS09475	ENOG4105EXC	Acyl-transferase
HPT03_RS09485	ENOG4105DTA	methyltransferase
HPT03_RS09510	ENOG4105D1S	lipid A biosynthesis
HPT03_RS09530	ENOG4105UEI	Transcriptional Regulator AraC Family
HPT03_RS09540	ENOG4105CV8	reductase
HPT03_RS09545	ENOG4105HEI	LysR family (Transcriptional regulator
HPT03_RS09550	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HPT03_RS09560	ENOG4108YS1	cytoplasmic protein
HPT03_RS09570	ENOG410849A	acetyltransferase, (GNAT) family
HPT03_RS09580	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HPT03_RS09585	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HPT03_RS09590	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
HPT03_RS09595	ENOG4105K4P	CoA-binding domain protein
HPT03_RS09600	ENOG4108Z5K	methylglyoxal synthase
HPT03_RS09605	ENOG41088T4	Helicase IV
HPT03_RS09610	ENOG4105EM2	membrane
HPT03_RS09630	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HPT03_RS09635	ENOG4105DAN	ATP-dependent protease
HPT03_RS09640	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HPT03_RS09645	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HPT03_RS09655	ENOG4108Q2G	(LipO)protein
HPT03_RS09660	ENOG4105DY2	Paraquat-inducible protein b
HPT03_RS09665	ENOG4105F1S	paraquat-inducible protein a
HPT03_RS09670	ENOG4105C5H	ABC transporter
HPT03_RS09675	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HPT03_RS09680	ENOG4105QVC	MOSC domain-containing protein
HPT03_RS09685	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HPT03_RS09690	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HPT03_RS09700	ENOG4105CD8	aminopeptidase N
HPT03_RS09705	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HPT03_RS09715	ENOG4105C5S	asparaginyl-tRNA synthetase
HPT03_RS09720	ENOG4105FCK	Membrane
HPT03_RS09725	ENOG4105CGF	Aromatic amino acid aminotransferase
HPT03_RS09850	ENOG4105CS6	Rhs element vgr protein
HPT03_RS09855	ENOG4108WC9	type VI secretion system effector, hcp1 family
HPT03_RS09905	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPT03_RS09940	ENOG4105GMB	type VI secretion system effector, hcp1 family
HPT03_RS09945	ENOG4105C5X	domain protein
HPT03_RS09950	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HPT03_RS09955	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HPT03_RS09960	ENOG4105F0S	class B acid phosphatase
HPT03_RS09965	ENOG4108UY2	Chloramphenicol acetyltransferase
HPT03_RS09970	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HPT03_RS09975	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HPT03_RS09980	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HPT03_RS09985	ENOG4106371	Methyltransferase
HPT03_RS09990	ENOG4107S90	membrAne
HPT03_RS09995	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HPT03_RS10000	ENOG4105W49	UPF0434 protein
HPT03_RS10010	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HPT03_RS10015	ENOG4105BZ1	(ABC) transporter
HPT03_RS10020	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HPT03_RS10025	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HPT03_RS10030	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HPT03_RS10035	ENOG4105CAT	Cytidine monophosphate kinase
HPT03_RS10040	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HPT03_RS10045	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HPT03_RS10060	ENOG4105HDK	L-asparaginase
HPT03_RS10065	ENOG4105DDY	UPF0142 protein ycaO
HPT03_RS10070	ENOG4105TMB	Formate nitrite transporter
HPT03_RS10075	ENOG4105C6N	Formate acetyltransferase
HPT03_RS10080	ENOG4105F1A	Pyruvate formate-lyase
HPT03_RS10090	ENOG4105DG4	malate L-lactate dehydrogenase
HPT03_RS10100	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HPT03_RS10105	ENOG4105D1H	recombination factor protein RarA
HPT03_RS10110	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HPT03_RS10115	ENOG4105CNU	cell division protein FtsK
HPT03_RS10120	ENOG4105EW9	transcriptional regulator AsnC family
HPT03_RS10125	ENOG4105C3M	thioredoxin reductase
HPT03_RS10130	ENOG4108JJ9	ABC, transporter
HPT03_RS10135	ENOG4108JJ8	(ABC) transporter
HPT03_RS10140	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HPT03_RS10150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPT03_RS10155	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HPT03_RS10160	ENOG4105VEQ	Cold shock protein
HPT03_RS10165	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPT03_RS10170	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HPT03_RS10175	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HPT03_RS10180	ENOG4105DWU	Membrane
HPT03_RS10185	ENOG4105CGD	Nad-dependent epimerase dehydratase
HPT03_RS10190	ENOG4105E5Z	arginine transporter ATP-binding subunit
HPT03_RS10195	ENOG4106PMH	Extracellular solute-binding protein family 3
HPT03_RS10200	ENOG4105GBT	ABC transporter
HPT03_RS10205	ENOG4105DMR	ABC, transporter
HPT03_RS10210	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HPT03_RS10215	ENOG4108RMJ	sensory transduction regulator
HPT03_RS10220	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
HPT03_RS10225	ENOG41090BQ	Glutaredoxin
HPT03_RS10230	ENOG4105D7V	transposase
HPT03_RS10235	ENOG4108RS6	transposase
HPT03_RS10240	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HPT03_RS10245	ENOG4105C44	Serine transporter
HPT03_RS10250	ENOG4105EJQ	L-serine dehydratase
HPT03_RS10255	ENOG4105CKU	formyltetrahydrofolate synthetase
HPT03_RS10260	ENOG4105DZ1	carboxypeptidase
HPT03_RS10265	ENOG4108TGY	Glutathione S-transferase
HPT03_RS10270	ENOG4107SRH	Nad-dependent epimerase dehydratase
HPT03_RS10275	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HPT03_RS10280	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HPT03_RS10290	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HPT03_RS10295	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HPT03_RS10300	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HPT03_RS10305	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HPT03_RS10310	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HPT03_RS10315	ENOG4105C0A	alcohol dehydrogenase
HPT03_RS10320	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
HPT03_RS10325	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HPT03_RS10335	ENOG4108RS6	transposase
HPT03_RS10340	ENOG4105EE5	Membrane protein terC
HPT03_RS10345	ENOG4105CEE	C4-dicarboxylate transporter
HPT03_RS10350	ENOG4108GAE	asmA family
HPT03_RS10355	ENOG4105DHP	deoxycytidine triphosphate deaminase
HPT03_RS10360	ENOG4105DBI	uridine monophosphokinase
HPT03_RS10365	ENOG4105D1F	ATP-binding protein
HPT03_RS10370	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HPT03_RS10375	ENOG4105VAW	lrga family
HPT03_RS10380	ENOG41067MG	lrgb family
HPT03_RS10385	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HPT03_RS10390	ENOG4107R1I	NAD-dependent malic enzyme
HPT03_RS10395	ENOG4107GZ4	SanA protein
HPT03_RS10400	ENOG4105DHF	Membrane
HPT03_RS10405	ENOG4105EUJ	GTP cyclohydrolase i
HPT03_RS10410	ENOG4105CBP	Major Facilitator
HPT03_RS10415	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HPT03_RS10420	ENOG4105D06	uba thif-type nad fad binding protein
HPT03_RS10435	ENOG4108URH	decarboxylase
HPT03_RS10445	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HPT03_RS10450	ENOG4105DVT	helicase
HPT03_RS10460	ENOG4105KHC	sulfurtransferase
HPT03_RS10470	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HPT03_RS10475	ENOG4105C1J	atp-dependent rna helicase
HPT03_RS10480	ENOG4107MVR	Transcriptional regulator
HPT03_RS10490	ENOG4105CJ1	ABC, transporter
HPT03_RS10495	ENOG4107QWP	ABC-2 type transporter
HPT03_RS10500	ENOG4107QWP	ABC-2 type transporter
HPT03_RS10505	ENOG4105HFZ	Membrane
HPT03_RS10510	ENOG4108ZAF	Molybdopterin
HPT03_RS10515	ENOG4105M00	molybdopterin converting factor, subunit 1
HPT03_RS10520	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPT03_RS10525	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPT03_RS10530	ENOG4105CHW	UPF0052 protein
HPT03_RS10540	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HPT03_RS10550	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPT03_RS10555	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPT03_RS10560	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HPT03_RS10565	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPT03_RS10570	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HPT03_RS10575	ENOG4108K4B	hydrolase
HPT03_RS10580	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS10585	ENOG4105E0C	molybdate abc transporter
HPT03_RS10590	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HPT03_RS10600	ENOG4105F4R	Transcriptional regulator mode
HPT03_RS10615	ENOG4105D5K	Hemolysin activator protein
HPT03_RS10620	ENOG4105DKW	ABC transporter
HPT03_RS10625	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HPT03_RS10630	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HPT03_RS10635	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HPT03_RS10655	ENOG4105UFD	tol-pal system protein YbgF
HPT03_RS10660	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HPT03_RS10665	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HPT03_RS10670	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HPT03_RS10680	ENOG4105E02	MotA TolQ exbB proton channel
HPT03_RS10685	ENOG4107YD3	Thioesterase
HPT03_RS10695	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPT03_RS10700	ENOG4105HEI	LysR family (Transcriptional regulator
HPT03_RS10705	ENOG4105KJB	cyd operon protein YbgE
HPT03_RS10715	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HPT03_RS10720	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPT03_RS10725	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HPT03_RS10730	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HPT03_RS10735	ENOG4105C7S	Dehydrogenase
HPT03_RS10740	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HPT03_RS10745	ENOG4105E33	succinate dehydrogenase
HPT03_RS10755	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HPT03_RS10760	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HPT03_RS10765	ENOG4105BZN	citrate synthase
HPT03_RS10775	ENOG4105C2C	drug resistance transporter, Bcr CflA
HPT03_RS10785	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
HPT03_RS10790	ENOG4105RD5	
HPT03_RS10795	ENOG4105DEG	Vwa containing coxe family protein
HPT03_RS10805	ENOG4107QNR	UPF0135 protein
HPT03_RS10810	ENOG4105XIQ	Protein of unknown function (DUF2517)
HPT03_RS10820	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
HPT03_RS10825	ENOG4108W15	Protein of unknown function (DUF1456)
HPT03_RS10830	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HPT03_RS10835	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HPT03_RS10840	ENOG4105EV9	Alpha Beta Hydrolase
HPT03_RS10845	ENOG4105NNH	LexA regulated protein
HPT03_RS10850	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HPT03_RS10855	ENOG41090R7	Ferric uptake
HPT03_RS10870	ENOG4105CX6	glutaminyL-tRNA synthetase
HPT03_RS10875	ENOG4105MPK	DNA polymerase III subunit theta
HPT03_RS10975	ENOG4105CNU	cell division protein FtsK
HPT03_RS11090	ENOG4105KUS	lysozyme
HPT03_RS11105	ENOG4105R3P	Inner membrane protein yagU
HPT03_RS11120	ENOG4105RWQ	Protein of unknown function (DUF1364)
HPT03_RS11135	ENOG4105CDU	Replicative dna helicase
HPT03_RS11240	ENOG4108UUM	single-stranded DNA-binding protein
HPT03_RS11265	ENOG4108I1J	Integrase
HPT03_RS11270	ENOG4105CI1	PTS System
HPT03_RS11275	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HPT03_RS11280	ENOG4105CE4	GlcNAc 6-P deacetylase
HPT03_RS11285	ENOG4105E2R	ROK family
HPT03_RS11335	ENOG4105C4W	S-formylglutathione hydrolase
HPT03_RS11340	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HPT03_RS11345	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HPT03_RS11350	ENOG4105C9A	Phoh family
HPT03_RS11355	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HPT03_RS11360	ENOG4108JU5	Magnesium and cobalt efflux protein
HPT03_RS11365	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HPT03_RS11375	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPT03_RS11395	ENOG4107RP9	extracellular solute-binding protein, family 3
HPT03_RS11400	ENOG4105EAD	ABC transporter
HPT03_RS11405	ENOG4105DRP	amino acid AbC transporter
HPT03_RS11410	ENOG4105CDA	abc transporter atp-binding protein
HPT03_RS11415	ENOG4105C8T	Leucyl-tRNA synthetase
HPT03_RS11420	ENOG4108U2H	Rare lipoprotein B
HPT03_RS11425	ENOG4105DJF	DNA polymerase III, delta' subunit
HPT03_RS11430	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HPT03_RS11440	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HPT03_RS11445	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HPT03_RS11450	ENOG4105CJN	penicillin-binding protein
HPT03_RS11455	ENOG4105CNI	cell division protein FtsW
HPT03_RS11460	ENOG4105K6T	rare lipoprotein A
HPT03_RS11465	ENOG4105DZ1	carboxypeptidase
HPT03_RS11470	ENOG4108Z43	UPF0250 protein
HPT03_RS11475	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HPT03_RS11480	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HPT03_RS11485	ENOG4107Z6W	Protein CrcB homolog
HPT03_RS11500	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPT03_RS11510	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HPT03_RS11525	ENOG4108IJ7	Glycine betaine
HPT03_RS11530	ENOG4108HQS	Glycine betaine
HPT03_RS11535	ENOG4105GIJ	Glycine betaine
HPT03_RS11540	ENOG4105X58	receptor
HPT03_RS11545	ENOG4105EQ0	Major Facilitator superfamily
HPT03_RS11550	ENOG4105NTK	Transcriptional repressor Mpra
HPT03_RS11555	ENOG4108UAU	isochorismatase
HPT03_RS11560	ENOG4105C6X	Major Facilitator
HPT03_RS11570	ENOG4105CW7	secretion protein, HlyD family
HPT03_RS11575	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPT03_RS11580	ENOG4105EIB	trna rrna methyltransferase
HPT03_RS11590	ENOG4106IUH	DTW domain containing protein
HPT03_RS11595	ENOG4105CD5	CoA-binding domain protein
HPT03_RS11600	ENOG4105JIM	Phosphatidylserine synthase
HPT03_RS11605	ENOG4105T42	(LipO)protein
HPT03_RS11635	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPT03_RS11640	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HPT03_RS11645	ENOG4105C34	Pseudouridine synthase
HPT03_RS11650	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPT03_RS11655	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HPT03_RS11660	ENOG4105CQC	Prephenate dehydratase
HPT03_RS11665	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HPT03_RS11685	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HPT03_RS11690	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HPT03_RS11695	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HPT03_RS11705	ENOG4105K5M	30s ribosomal protein S16
HPT03_RS11710	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPT03_RS11715	ENOG4106KVJ	cytochrome C assembly protein
HPT03_RS11720	ENOG4108JU6	CBS domain protein
HPT03_RS11725	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HPT03_RS11730	ENOG4105D9M	gamma-glutamylcysteine synthetase
HPT03_RS11760	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HPT03_RS11765	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HPT03_RS11770	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HPT03_RS11775	ENOG4107TH8	cina domain protein
HPT03_RS11780	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HPT03_RS11785	ENOG4105CEY	Amp-dependent synthetase and ligase
HPT03_RS11790	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPT03_RS11795	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HPT03_RS11800	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HPT03_RS11805	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
HPT03_RS11810	ENOG4105V1F	Fermentation respiration switch protein
HPT03_RS11815	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HPT03_RS11820	ENOG4105CIN	aminoacyl-histidine dipeptidase
HPT03_RS11825	ENOG4105E0K	tonB-dependent siderophore receptor
HPT03_RS11830	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HPT03_RS11840	ENOG4105VDW	Csbd family
HPT03_RS11850	ENOG4105CJ2	(LipO)protein
HPT03_RS11855	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HPT03_RS11860	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HPT03_RS11865	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HPT03_RS11870	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HPT03_RS11875	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HPT03_RS11880	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HPT03_RS11885	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
HPT03_RS11890	ENOG4105E7A	Glutamine amidotransferase
HPT03_RS11895	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HPT03_RS11900	ENOG4107QPN	acyl-Coa dehydrogenase
HPT03_RS11910	ENOG4105RQF	LysR family Transcriptional regulator
HPT03_RS11915	ENOG4105EJC	lysr family transcriptional regulator
HPT03_RS11935	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HPT03_RS11940	ENOG4105D7Z	glutathione synthase
HPT03_RS11945	ENOG4108UJU	UPF0301 protein
HPT03_RS11950	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HPT03_RS11955	ENOG4105CZX	twitching motility protein
HPT03_RS11960	ENOG4105DFA	alanine racemase domain protein
HPT03_RS11965	ENOG4105II7	pyrroline-5-carboxylate reductase
HPT03_RS11970	ENOG4108VIA	integral membrane protein
HPT03_RS11975	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HPT03_RS11980	ENOG4105CSA	Coproporphyrinogen iii oxidase
HPT03_RS11990	ENOG4105K33	Periplasmic Protein
HPT03_RS11995	ENOG4105CSV	Glutaminase
HPT03_RS12000	ENOG41090ED	Protein with unknown function (DUF469)
HPT03_RS12010	ENOG4105CEN	a g-specific adenine glycosylase
HPT03_RS12015	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HPT03_RS12020	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HPT03_RS12055	ENOG4105EFA	4-hydroxyphenylacetate
HPT03_RS12080	ENOG4108RS6	transposase
HPT03_RS12125	ENOG4105CXN	decarboxylase
HPT03_RS12130	ENOG4105D5Q	Arginine ornithine antiporter
HPT03_RS12135	ENOG4108WUH	Transcriptional regulator, TetR family
HPT03_RS12140	ENOG4105D4X	repressor
HPT03_RS12145	ENOG4105C5Y	PTS System
HPT03_RS12150	ENOG4105C71	hydrolase family 65, central catalytic
HPT03_RS12155	ENOG4107URF	beta-phospho-glucomutase
HPT03_RS12190	ENOG4105QNJ	serralysin (EC 3.4.24.40)
HPT03_RS12195	ENOG4108JJ6	Type I secretion system ATPase
HPT03_RS12200	ENOG4107QZV	Type I secretion membrane fusion protein
HPT03_RS12205	ENOG4105DFG	type I secretion outer membrane protein
HPT03_RS12210	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPT03_RS12220	ENOG4105VTS	DnaJ-like, subfamily C
HPT03_RS12225	ENOG4105CFC	Transporter
HPT03_RS12240	ENOG4105H8W	Fimbrial protein
HPT03_RS12255	ENOG4106P2F	Pfam:Pili_assembly_C
HPT03_RS12260	ENOG4106PG1	outer membrane usher protein
HPT03_RS12265	ENOG4108ZJG	MrfB protein
HPT03_RS12270	ENOG4105HMV	Fimbrial protein
HPT03_RS12275	ENOG4108W9T	type 1 fimbriae regulatory protein
HPT03_RS12295	ENOG4105NEV	Fimbrial
HPT03_RS12300	ENOG4105UGQ	Fimbrial
HPT03_RS12305	ENOG4108FZ9	Chaperone
HPT03_RS12310	ENOG4106PG1	outer membrane usher protein
HPT03_RS12315	ENOG4105HMV	Fimbrial protein
HPT03_RS12320	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HPT03_RS12335	ENOG4105C94	Transporter
HPT03_RS12340	ENOG4108V8F	Transcriptional regulator, MarR family
HPT03_RS12350	ENOG4107UWN	reductase
HPT03_RS12355	ENOG4105DUX	Transporter
HPT03_RS12360	ENOG4105YB8	TM2 domain containing protein
HPT03_RS12365	ENOG4105D2N	Aldolase
HPT03_RS12370	ENOG4105BZA	Phosphoglycerate kinase
HPT03_RS12375	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HPT03_RS12380	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HPT03_RS12430	ENOG4105E0A	ABC, transporter
HPT03_RS12435	ENOG4105EHG	Permease protein
HPT03_RS12445	ENOG4107RZZ	dna polymerase iii epsilon subunit
HPT03_RS12450	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPT03_RS12455	ENOG4105D1A	Methyltransferase
HPT03_RS12460	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPT03_RS12465	ENOG4105E9H	Lytic Murein transglycosylase
HPT03_RS12470	ENOG4107RA9	decarboxylase
HPT03_RS12475	ENOG4105C8P	)-transporter
HPT03_RS12480	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HPT03_RS12485	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HPT03_RS12490	ENOG4105DXN	mazG family
HPT03_RS12495	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HPT03_RS12500	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HPT03_RS12510	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HPT03_RS12520	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HPT03_RS12525	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HPT03_RS12530	ENOG4105BZ4	penicillin-binding protein
HPT03_RS12535	ENOG4105CQ7	ATP-dependent helicase
HPT03_RS12540	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HPT03_RS12545	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HPT03_RS12555	ENOG4105DJ0	Poly(A) Polymerase
HPT03_RS12560	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HPT03_RS12565	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HPT03_RS12570	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HPT03_RS12575	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HPT03_RS12580	ENOG4108KX4	response regulator
HPT03_RS12585	ENOG4105BZU	Histidine kinase
HPT03_RS12590	ENOG4105CXY	transporter
HPT03_RS12595	ENOG4105C4Y	ABC transporter
HPT03_RS12600	ENOG4107RCV	ABC transporter, permease
HPT03_RS12605	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS12610	ENOG4105BZC	d-serine deaminase
HPT03_RS12615	ENOG4105C6Z	Gluconate
HPT03_RS12620	ENOG4105W8I	Transcriptional regulator
HPT03_RS12625	ENOG4106032	Glutathionylspermidine synthase
HPT03_RS12640	ENOG4105WP5	
HPT03_RS12655	ENOG4105DBE	peroxidase
HPT03_RS12665	ENOG4108J2R	molybdopterin oxidoreductase
HPT03_RS12670	ENOG4105QAX	Iron-sulfur
HPT03_RS12685	ENOG4105D0M	Protease HtpX homolog
HPT03_RS12690	ENOG4105R71	cytoplasmic protein
HPT03_RS12695	ENOG41079KZ	Major Facilitator Superfamily
HPT03_RS12700	ENOG4105E3A	(ABC) transporter
HPT03_RS12705	ENOG4105DA5	(ABC) transporter
HPT03_RS12710	ENOG41077A9	carbonic anhydrase
HPT03_RS12715	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HPT03_RS12720	ENOG4105E3B	Multicopper oxidase
HPT03_RS12725	ENOG4108ZRK	uncharacterized protein yacC
HPT03_RS12755	ENOG4105EQN	UPF0261 protein
HPT03_RS12765	ENOG4105DGA	Diaminopimelate dehydrogenase
HPT03_RS12770	ENOG4105UQX	Mate efflux family protein
HPT03_RS12780	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HPT03_RS12785	ENOG4105CEE	C4-dicarboxylate transporter
HPT03_RS12795	ENOG4105CKI	cobalamin synthesis protein
HPT03_RS12800	ENOG4105VCD	cytoplasmic protein
HPT03_RS12805	ENOG4105D22	carbon starvation protein
HPT03_RS12810	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HPT03_RS12815	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HPT03_RS12820	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HPT03_RS12825	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HPT03_RS12840	ENOG4105EGS	Mechanosensitive ion channel
HPT03_RS12845	ENOG41090EX	DsrE family
HPT03_RS12850	ENOG4107XI7	Tetr family transcriptional regulator
HPT03_RS12855	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HPT03_RS12860	ENOG4105BZS	acriflavin resistance protein
HPT03_RS12870	ENOG4105KF5	hemolysin expression-modulating protein
HPT03_RS12880	ENOG4105C29	acyl-CoA thioesterase
HPT03_RS12885	ENOG4105BZU	Histidine kinase
HPT03_RS12890	ENOG4108YZA	Nitrogen regulatory protein pii
HPT03_RS12895	ENOG4105BZ1	(ABC) transporter
HPT03_RS12900	ENOG4105BZ1	(ABC) transporter
HPT03_RS12905	ENOG4108XM1	transcriptional regulator AsnC family
HPT03_RS12910	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HPT03_RS12915	ENOG4108TGP	Thioesterase superfamily protein
HPT03_RS12920	ENOG4105KQC	Competence protein
HPT03_RS12925	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HPT03_RS12930	ENOG4105K70	DNA-binding protein
HPT03_RS12935	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HPT03_RS12940	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HPT03_RS12945	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPT03_RS12950	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HPT03_RS12955	ENOG4105M85	Bola protein
HPT03_RS12960	ENOG4105IEY	(LipO)protein
HPT03_RS12965	ENOG4105EYM	Major Facilitator superfamily
HPT03_RS12970	ENOG4105C1J	atp-dependent rna helicase
HPT03_RS12975	ENOG4108NFH	Sugar hydrolase
HPT03_RS12980	ENOG4105E2S	oxidase) subunit II
HPT03_RS12985	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HPT03_RS12990	ENOG4105CCU	oxidase (Subunit III)
HPT03_RS12995	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HPT03_RS13000	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HPT03_RS13005	ENOG4107RDB	Major Facilitator
HPT03_RS13010	ENOG4108VPT	UPF0234 protein
HPT03_RS13015	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HPT03_RS13020	ENOG4107S0N	DJ-1 family
HPT03_RS13030	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HPT03_RS13035	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPT03_RS13040	ENOG4105CTB	Polyprenyl synthetase
HPT03_RS13045	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HPT03_RS13050	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HPT03_RS13055	ENOG4105C2J	ABC transporter
HPT03_RS13060	ENOG4105CNN	ABC, transporter
HPT03_RS13065	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HPT03_RS13070	ENOG4108RVA	ribokinase
HPT03_RS13075	ENOG4105ETE	Transcriptional regulator (LacI family
HPT03_RS13080	ENOG4105D7V	transposase
HPT03_RS13085	ENOG4108RS6	transposase
HPT03_RS13090	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HPT03_RS13095	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HPT03_RS13100	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HPT03_RS13105	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HPT03_RS13110	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HPT03_RS13115	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HPT03_RS13120	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPT03_RS13125	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPT03_RS13130	ENOG4105VIE	preprotein translocase, subunit YajC
HPT03_RS13135	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HPT03_RS13140	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HPT03_RS13145	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HPT03_RS13150	ENOG4105D3R	alkyl hydroperoxide reductase
HPT03_RS13160	ENOG4108UIF	Chaperone
HPT03_RS13185	ENOG4108PU5	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPT03_RS13190	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
HPT03_RS13195	ENOG4105JVW	
HPT03_RS13200	ENOG4108393	oxidoreductase Fe-S subunit
HPT03_RS13205	ENOG4108NWD	Cytochrome
HPT03_RS13240	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HPT03_RS13245	ENOG4105BZU	Histidine kinase
HPT03_RS13250	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPT03_RS13255	ENOG4107RH8	nuclease SbcCD subunit D
HPT03_RS13260	ENOG4105EYH	Exonuclease
HPT03_RS13280	ENOG4105CGH	5'-nucleotidase
HPT03_RS13285	ENOG41083KI	ribonuclease, T2
HPT03_RS13290	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HPT03_RS13300	ENOG4105DH7	May be involved in recombination (By similarity)
HPT03_RS13310	ENOG41066VF	YeeE YedE family protein
HPT03_RS13315	ENOG4105C45	hydrogenase expression formation protein (HypE)
HPT03_RS13320	ENOG4105CQS	hydrogenase expression formation protein HypD
HPT03_RS13325	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
HPT03_RS13330	ENOG4107RSS	Hydrogenase accessory protein HypB
HPT03_RS13335	ENOG4108WGS	hydrogenase 2-specific chaperone
HPT03_RS13340	ENOG4108USZ	hydrogenase
HPT03_RS13345	ENOG4105DPX	Hydrogenase, large subunit
HPT03_RS13350	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
HPT03_RS13355	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HPT03_RS13360	ENOG4105E3S	small subunit
HPT03_RS13370	ENOG4108ZZF	transport protein (ExbD)
HPT03_RS13375	ENOG4105CWK	Biopolymer transport protein, ExbB
HPT03_RS13380	ENOG4105C28	cystathionine
HPT03_RS13385	ENOG4108K81	inner membrane protein YghB
HPT03_RS13390	ENOG4108I6A	alcohol dehydrogenase
HPT03_RS13395	ENOG4105CV8	reductase
HPT03_RS13410	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HPT03_RS13420	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HPT03_RS13425	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HPT03_RS13430	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HPT03_RS13435	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPT03_RS13440	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HPT03_RS13445	ENOG4105DTN	riboflavin biosynthesis protein ribF
HPT03_RS13455	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HPT03_RS13460	ENOG41063Z6	transcriptional regulator, lysR family
HPT03_RS13465	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HPT03_RS13470	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPT03_RS13475	ENOG4105CFG	Acts as a chaperone (By similarity)
HPT03_RS13480	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HPT03_RS13495	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HPT03_RS13500	ENOG4105D1Q	UPF0246 protein
HPT03_RS13515	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HPT03_RS13525	ENOG41065U4	response regulator
HPT03_RS13530	ENOG4108RH0	Crea protein
HPT03_RS13535	ENOG4105UEI	Transcriptional Regulator AraC Family
HPT03_RS13540	ENOG4105CVJ	phosphoglycerate mutase
HPT03_RS13545	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HPT03_RS13550	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HPT03_RS13555	ENOG4107SC1	transglycosylase
HPT03_RS13560	ENOG4105C5H	ABC transporter
HPT03_RS13570	ENOG4108SF5	RNA Polymerase
HPT03_RS13580	ENOG4105PE1	Receptor
HPT03_RS13585	ENOG4105CQ0	ABC transporter
HPT03_RS13590	ENOG4107RAN	Peptidase, M16
HPT03_RS13600	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HPT03_RS13605	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HPT03_RS13610	ENOG4106W5V	Membrane
HPT03_RS13615	ENOG4105NE1	Conserved Protein
HPT03_RS13620	ENOG41090KG	Inner membrane protein YqjE
HPT03_RS13630	ENOG4108VBZ	doxx family
HPT03_RS13635	ENOG4105CWB	LysR family transcriptional Regulator
HPT03_RS13640	ENOG4108CNN	domain protein
HPT03_RS13650	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HPT03_RS13660	ENOG41082RQ	UPF0102 protein
HPT03_RS13665	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HPT03_RS13670	ENOG4105W4M	Transport-associated protein
HPT03_RS13675	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HPT03_RS13680	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HPT03_RS13685	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HPT03_RS13690	ENOG4105CQM	Urea amidohydrolase subunit alpha
HPT03_RS13695	ENOG4105KI2	Urea amidohydrolase subunit beta
HPT03_RS13700	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HPT03_RS13705	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HPT03_RS13710	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
HPT03_RS13715	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HPT03_RS13720	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HPT03_RS13725	ENOG4105BZU	Histidine kinase
HPT03_RS13730	ENOG4105CBC	glutamate synthase
HPT03_RS13735	ENOG4105BZ8	glutamate synthase
HPT03_RS13745	ENOG4105CH2	amidohydrolase
HPT03_RS13755	ENOG4105KB2	stringent starvation protein b
HPT03_RS13760	ENOG4107MKT	Stringent starvation protein a
HPT03_RS13765	ENOG4108UJD	30S ribosomal protein S9
HPT03_RS13770	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HPT03_RS13775	ENOG4105D6Z	AFG1 family ATPase
HPT03_RS13780	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HPT03_RS13785	ENOG4105C0H	protease
HPT03_RS13790	ENOG4105C0H	protease
HPT03_RS13810	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HPT03_RS13815	ENOG4105VFK	BolA family
HPT03_RS13825	ENOG4105E3I	toluene tolerance
HPT03_RS13830	ENOG4107PE3	Mammalian cell entry related domain protein
HPT03_RS13835	ENOG4105CY3	ABC transporter, permease
HPT03_RS13840	ENOG4105DHJ	ABC, transporter
HPT03_RS13845	ENOG4105FEU	K -dependent Na -Ca exchanger
HPT03_RS13850	ENOG4105C2X	Arabinose 5-phosphate isomerase
HPT03_RS13855	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HPT03_RS13860	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HPT03_RS13865	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HPT03_RS13870	ENOG4108IUZ	ABC transporter
HPT03_RS13875	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPT03_RS13880	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HPT03_RS13885	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HPT03_RS13890	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HPT03_RS13895	ENOG41080Z8	PHOSPHOCARRIER protein
HPT03_RS13900	ENOG4105NXH	GreA GreB family elongation factor
HPT03_RS13905	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HPT03_RS13910	ENOG4105N42	UPF0307 protein
HPT03_RS13915	ENOG41067XF	inhibitor
HPT03_RS13925	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HPT03_RS13935	ENOG4105QD6	exported protein
HPT03_RS13940	ENOG4105C03	ribonuclease
HPT03_RS13945	ENOG4108Z03	MAF-like protein
HPT03_RS13950	ENOG4105VQ7	Rod shape-determining protein MreD
HPT03_RS13955	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HPT03_RS13965	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HPT03_RS13970	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HPT03_RS13975	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HPT03_RS13980	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HPT03_RS13985	ENOG4105RG0	Membrane
HPT03_RS13990	ENOG4108IA2	Sodium pantothenate symporter
HPT03_RS13995	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HPT03_RS14005	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HPT03_RS14030	ENOG4105DJ2	Major Facilitator Superfamily
HPT03_RS14035	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HPT03_RS14040	ENOG4105BZ7	extracellular solute-binding protein family 1
HPT03_RS14050	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS14055	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS14060	ENOG4108K0D	peptidase, M48
HPT03_RS14065	ENOG4108INS	Transcriptional regulator
HPT03_RS14075	ENOG4105U59	-acetyltransferase
HPT03_RS14080	ENOG4105BZW	Glycerate kinase
HPT03_RS14085	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPT03_RS14090	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HPT03_RS14095	ENOG4105CAK	Cell division ATP-binding protein ftsE
HPT03_RS14100	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPT03_RS14105	ENOG4106H78	methyltransferase
HPT03_RS14110	ENOG4105MG3	Membrane
HPT03_RS14120	ENOG4107FS9	Membrane
HPT03_RS14125	ENOG4105C59	p-type ATPase
HPT03_RS14145	ENOG4108RS6	transposase
HPT03_RS14150	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HPT03_RS14155	ENOG4105EX9	Membrane
HPT03_RS14165	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HPT03_RS14175	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HPT03_RS14180	ENOG4105CXY	transporter
HPT03_RS14185	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HPT03_RS14190	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HPT03_RS14205	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HPT03_RS14210	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HPT03_RS14235	ENOG4108JUA	Transcriptional regulator
HPT03_RS14250	ENOG4105DIJ	Phosphoethanolamine transferase
HPT03_RS14260	ENOG41076YT	nitrate reductase, gamma subunit
HPT03_RS14265	ENOG4105R3A	Nitrate reductase
HPT03_RS14270	ENOG4108IUE	nitrate reductase beta subunit
HPT03_RS14275	ENOG4105CRU	nitrate reductase, alpha subunit
HPT03_RS14280	ENOG4105DQQ	Major facilitator superfamily MFS_1
HPT03_RS14285	ENOG4105BZU	Histidine kinase
HPT03_RS14290	ENOG4105WH1	Two component transcriptional regulator luxr family
HPT03_RS14295	ENOG4105HEI	LysR family (Transcriptional regulator
HPT03_RS14310	ENOG4105HF0	Membrane
HPT03_RS14315	ENOG4108JIK	carboxylase
HPT03_RS14320	ENOG4105P4J	Allophanate hydrolase, subunit 1
HPT03_RS14325	ENOG4105E7W	lamb ycsf family protein
HPT03_RS14330	ENOG4105C5A	transporter
HPT03_RS14360	ENOG4108RR8	protoporphyrinogen oxidase
HPT03_RS14365	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HPT03_RS14370	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HPT03_RS14375	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HPT03_RS14380	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPT03_RS14385	ENOG4105CHU	acetyl-coa acetyltransferase
HPT03_RS14395	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HPT03_RS14400	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HPT03_RS14405	ENOG4105MDZ	Transcriptional activator rfaH
HPT03_RS14410	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HPT03_RS14415	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HPT03_RS14420	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HPT03_RS14425	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HPT03_RS14430	ENOG4105JC1	sterol-binding domain protein
HPT03_RS14435	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HPT03_RS14440	ENOG4105CGY	Dna recombination protein
HPT03_RS14445	ENOG4108KF1	Membrane
HPT03_RS14455	ENOG4107SXA	Phosphorylase
HPT03_RS14460	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
HPT03_RS14470	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HPT03_RS14475	ENOG4105DZ2	Transcriptional regulator
HPT03_RS14480	ENOG4105EMK	carboxylate amino acid amine transporter
HPT03_RS14485	ENOG4105EEQ	Na H antiporter
HPT03_RS14490	ENOG4108MK9	spermidine N(1)-acetyltransferase
HPT03_RS14495	ENOG4105C7N	Xanthine uracil vitamin C permease
HPT03_RS14515	ENOG4105M71	acetolactate synthase 1 regulatory subunit
HPT03_RS14520	ENOG4105C7K	acetolactate synthase
HPT03_RS14535	ENOG4105HX0	Transcriptional regulator
HPT03_RS14545	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPT03_RS14555	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HPT03_RS14560	ENOG4107FB0	transcriptional regulator DeoR family
HPT03_RS14570	ENOG4108S2Y	peptide Chain Release factor
HPT03_RS14585	ENOG4105D7V	transposase
HPT03_RS14610	ENOG4105EB3	Histidine kinase
HPT03_RS14630	ENOG4107R6D	beta-lactam binding protein AmpH
HPT03_RS14635	ENOG4108K5H	permease YjgP YjgQ family protein
HPT03_RS14640	ENOG4108M8S	permease YjgP YjgQ family protein
HPT03_RS14645	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HPT03_RS14650	ENOG4105MYG	DNA polymerase iii, chi subunit
HPT03_RS14655	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HPT03_RS14660	ENOG4108MJ3	acetyltransferase
HPT03_RS14665	ENOG4105VYH	
HPT03_RS14670	ENOG4105EUB	pirin domain protein
HPT03_RS14675	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HPT03_RS14680	ENOG4105DBV	ornithine carbamoyltransferase
HPT03_RS14690	ENOG4105CXT	aspartate transcarbamylase
HPT03_RS14695	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HPT03_RS14700	ENOG4105KME	endoribonuclease L-psp
HPT03_RS14705	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HPT03_RS14710	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HPT03_RS14730	ENOG4105ZY9	UPF0379 protein ybiM
HPT03_RS14735	ENOG41082IR	Excinuclease ABC C subunit domain protein
HPT03_RS14740	ENOG4108YYD	acetyltransferase
HPT03_RS14775	ENOG4108T65	Fimbrial
HPT03_RS14780	ENOG4108SQA	Fimbrial
HPT03_RS14785	ENOG4105CW0	outer membrane usher protein
HPT03_RS14790	ENOG4108NAE	Fimbrial chaperone protein
HPT03_RS14795	ENOG4108RQP	Major type 1 subunit fimbrin
HPT03_RS14810	ENOG4105J12	Multidrug resistance protein mdtN
HPT03_RS14815	ENOG4108HRK	Histidine kinase
HPT03_RS14820	ENOG4108NEV	two component transcriptional regulator, LytTR family
HPT03_RS14835	ENOG4105C1J	atp-dependent rna helicase
HPT03_RS14845	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HPT03_RS14850	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HPT03_RS14855	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HPT03_RS14860	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HPT03_RS14865	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HPT03_RS14870	ENOG4105CHV	Transcription elongation factor NusA
HPT03_RS14875	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HPT03_RS14890	ENOG4105NTZ	Preprotein translocase subunit SecG
HPT03_RS14895	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HPT03_RS14900	ENOG4105EEI	dihydropteroate synthase
HPT03_RS14905	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPT03_RS14910	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HPT03_RS14915	ENOG4105HBR	Rna-binding protein
HPT03_RS14920	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HPT03_RS14925	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HPT03_RS14930	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPT03_RS14935	ENOG4105K46	50S ribosomal protein l27
HPT03_RS14940	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HPT03_RS14945	ENOG4105EAH	synthase
HPT03_RS14960	ENOG4105HVQ	Regulatory factor of maltose metabolism
HPT03_RS14965	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HPT03_RS14970	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HPT03_RS14975	ENOG4105DFU	Cell wall formation (By similarity)
HPT03_RS14980	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HPT03_RS14985	ENOG4105F0N	pyrophosphate phospho-hydrolase
HPT03_RS15005	ENOG4108ZHD	aig2 family
HPT03_RS15010	ENOG4105MA0	exported protein
HPT03_RS15015	ENOG4105CFU	surface antigen
HPT03_RS15020	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HPT03_RS15025	ENOG4105C37	(CBS) domain
HPT03_RS15030	ENOG41061GZ	Protein of unknown function (DUF1107)
HPT03_RS15035	ENOG4108UUE	Transcriptional regulator
HPT03_RS15040	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HPT03_RS15045	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HPT03_RS15050	ENOG4105C26	Dehydrogenase
HPT03_RS15055	ENOG4105D7V	transposase
HPT03_RS15060	ENOG4108RS6	transposase
HPT03_RS15065	ENOG4108MEK	Metal-binding protein YodA
HPT03_RS15070	ENOG4105YK5	50S ribosomal protein L36
HPT03_RS15075	ENOG4105NRA	50s ribosomal protein l31 type b
HPT03_RS15080	ENOG4105FHY	Opacity-associated protein A
HPT03_RS15085	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HPT03_RS15090	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HPT03_RS15095	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HPT03_RS15100	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HPT03_RS15105	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HPT03_RS15110	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HPT03_RS15115	ENOG4105KPV	Transcriptional regulator
HPT03_RS15120	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HPT03_RS15125	ENOG4105EPW	hflc protein
HPT03_RS15130	ENOG4107QJR	hflk protein
HPT03_RS15135	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HPT03_RS15140	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HPT03_RS15145	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HPT03_RS15150	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HPT03_RS15155	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HPT03_RS15160	ENOG4105K8N	protein family UPF0079, ATPase
HPT03_RS15165	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HPT03_RS15195	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HPT03_RS15200	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HPT03_RS15205	ENOG4105DJ4	phosphatidylserine decarboxylase
HPT03_RS15210	ENOG4105EGS	Mechanosensitive ion channel
HPT03_RS15220	ENOG4108S54	Fimbrial protein
HPT03_RS15225	ENOG4108AF8	Chaperone
HPT03_RS15230	ENOG4105CW0	outer membrane usher protein
HPT03_RS15240	ENOG4108RS6	transposase
HPT03_RS15245	ENOG4105D7V	transposase
HPT03_RS15250	ENOG4105DQF	Hydrolase
HPT03_RS15255	ENOG4108EUD	Lysophospholipase
HPT03_RS15260	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HPT03_RS15265	ENOG4105HDD	phospholipase
HPT03_RS15270	ENOG4108VUY	thioesterase Superfamily protein
HPT03_RS15275	ENOG4105FR1	rard protein
HPT03_RS15285	ENOG4105C4R	Atp-dependent dna helicase
HPT03_RS15290	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HPT03_RS15295	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HPT03_RS15300	ENOG4105CT0	Protein of unknown function, DUF484
HPT03_RS15305	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HPT03_RS15310	ENOG4105S7Z	(LipO)protein
HPT03_RS15315	ENOG4105XQ6	frataxin-like protein
HPT03_RS15320	ENOG4107T0K	Adenylate cyclase
HPT03_RS15325	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HPT03_RS15335	ENOG4105ECF	c-methyltransferase
HPT03_RS15340	ENOG410601J	HemY protein
HPT03_RS15370	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HPT03_RS15375	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
HPT03_RS15380	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
HPT03_RS15385	ENOG4105EGZ	biosynthesis protein
HPT03_RS15390	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HPT03_RS15395	ENOG4108WJ1	acetyltransferase
HPT03_RS15400	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HPT03_RS15405	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPT03_RS15410	ENOG4108IJ1	Dehydrogenase
HPT03_RS15415	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HPT03_RS15420	ENOG4105SFE	lipopolysaccharide biosynthesis protein
HPT03_RS15425	ENOG4105ESV	Glycosyl transferase, family 4
HPT03_RS15430	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HPT03_RS15440	ENOG4105C1J	atp-dependent rna helicase
HPT03_RS15445	ENOG4105C9X	ppx gppa phosphatase
HPT03_RS15450	ENOG4105C4R	Atp-dependent dna helicase
HPT03_RS15460	ENOG4105VXN	addiction module toxin, RelE StbE family
HPT03_RS15465	ENOG4105D7V	transposase
HPT03_RS15475	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HPT03_RS15480	ENOG4105EMY	transcriptional regulator
HPT03_RS15485	ENOG4105C7B	Threonine dehydratase
HPT03_RS15490	ENOG4105C01	Dihydroxy-acid dehydratase
HPT03_RS15495	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HPT03_RS15500	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HPT03_RS15515	ENOG4105C0P	Mg chelatase subunit ChlI
HPT03_RS15520	ENOG4108WFC	UPF0438 protein yifE
HPT03_RS15525	ENOG4105CVI	Transcriptional regulator
HPT03_RS15565	ENOG4108Z0R	Transferase
HPT03_RS15570	ENOG4105SG3	Protein of unknown function (DUF1488)
HPT03_RS15575	ENOG4105E2X	shikimate dehydrogenase
HPT03_RS15580	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPT03_RS15585	ENOG4108WI1	Dna topoisomerase
HPT03_RS15590	ENOG4105C79	DNA protecting protein DprA
HPT03_RS15595	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HPT03_RS15600	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HPT03_RS15605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HPT03_RS15610	ENOG4105C1A	potassium transporter peripheral membrane
HPT03_RS15615	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HPT03_RS15620	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HPT03_RS15625	ENOG4105W1Y	Transcriptional regulator
HPT03_RS15630	ENOG4108ZT0	50S ribosomal protein l17
HPT03_RS15640	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HPT03_RS15645	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HPT03_RS15650	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPT03_RS15655	ENOG41067V7	50S ribosomal protein L36
HPT03_RS15660	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HPT03_RS15665	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HPT03_RS15670	ENOG4105VPB	50S ribosomal protein L30
HPT03_RS15675	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HPT03_RS15680	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HPT03_RS15685	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HPT03_RS15690	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HPT03_RS15695	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HPT03_RS15700	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPT03_RS15705	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HPT03_RS15710	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HPT03_RS15715	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HPT03_RS15720	ENOG41083MP	50s ribosomal protein l29
HPT03_RS15725	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HPT03_RS15735	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HPT03_RS15740	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HPT03_RS15745	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPT03_RS15750	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HPT03_RS15755	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HPT03_RS15760	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HPT03_RS15780	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HPT03_RS15805	ENOG4105CS9	pantothenic acid kinase
HPT03_RS15810	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HPT03_RS15815	ENOG4105D4A	Cell wall formation (By similarity)
HPT03_RS15850	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HPT03_RS15855	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HPT03_RS15860	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HPT03_RS15865	ENOG4108Y73	Membrane
HPT03_RS15875	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HPT03_RS15880	ENOG4105C5Q	Transcriptional regulator
HPT03_RS15885	ENOG4105CH7	arginosuccinase
HPT03_RS15890	ENOG4105CDH	Citrulline--aspartate ligase
HPT03_RS15895	ENOG4105CAS	nag kinase
HPT03_RS15900	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HPT03_RS15905	ENOG4105CWC	Acetylornithine deacetylase
HPT03_RS15910	ENOG4105C7K	acetolactate synthase
HPT03_RS15930	ENOG4107R11	Transcriptional regulator
HPT03_RS15935	ENOG4105CSH	Transporter
HPT03_RS15940	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HPT03_RS15945	ENOG4105K64	Glycosyl transferase, family 2
HPT03_RS15950	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HPT03_RS15960	ENOG4108TEB	UPF0114 protein
HPT03_RS15965	ENOG4105CFH	Aspartokinase
HPT03_RS15970	ENOG4105C28	cystathionine
HPT03_RS15975	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HPT03_RS15985	ENOG41082DI	50s ribosomal protein l31
HPT03_RS15990	ENOG4105C25	Primosomal protein n'
HPT03_RS15995	ENOG4105ETE	Transcriptional regulator (LacI family
HPT03_RS16000	ENOG41063M6	Cell Division Protein
HPT03_RS16005	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HPT03_RS16010	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HPT03_RS16015	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HPT03_RS16020	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HPT03_RS16025	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HPT03_RS16030	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HPT03_RS16035	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HPT03_RS16040	ENOG4105E5M	Multidrug resistance protein D
HPT03_RS16045	ENOG4105DP0	ferredoxin-NADP reductase
HPT03_RS16050	ENOG4108VTS	Membrane
HPT03_RS16055	ENOG4105EBK	exported protein
HPT03_RS16060	ENOG4105CP7	Triose-phosphate isomerase
HPT03_RS16065	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HPT03_RS16070	ENOG4105CTQ	phosphohexokinase
HPT03_RS16075	ENOG4105CHR	reductase
HPT03_RS16080	ENOG4105FMW	periplasmic
HPT03_RS16085	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HPT03_RS16090	ENOG4105E0F	Histidine kinase
HPT03_RS16105	ENOG4105KPE	licD family
HPT03_RS16110	ENOG4105CG5	Glycosyl transferase (Group 1
HPT03_RS16120	ENOG4105K64	Glycosyl transferase, family 2
HPT03_RS16125	ENOG4108RYC	glycosyltransferase
HPT03_RS16130	ENOG4105DMT	epimerase dehydratase
HPT03_RS16145	ENOG4108I6E	Sulfatase
HPT03_RS16150	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HPT03_RS16155	ENOG4107S6X	Glycosyl transferase, family 2
HPT03_RS16160	ENOG4105D7W	serine acetyltransferase
HPT03_RS16165	ENOG4105D7W	serine acetyltransferase
HPT03_RS16175	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HPT03_RS16180	ENOG4107YZP	Rhodanese domain protein
HPT03_RS16190	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HPT03_RS16195	ENOG41063SB	peptidase
HPT03_RS16200	ENOG4105PXI	polysaccharide deacetylase
HPT03_RS16210	ENOG4105CPQ	Dehydrogenase
HPT03_RS16215	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPT03_RS16220	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HPT03_RS16225	ENOG4105XA0	heptosyltransferase ii
HPT03_RS16230	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HPT03_RS16240	ENOG4105DKP	glycosyl transferase, family 9
HPT03_RS16255	ENOG4105CPK	Glycosyl transferase (Group 1
HPT03_RS16265	ENOG4105DKP	glycosyl transferase, family 9
HPT03_RS16270	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HPT03_RS16280	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HPT03_RS16285	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HPT03_RS16290	ENOG4108FRV	O-antigen ligase
HPT03_RS16300	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPT03_RS16310	ENOG4105CPK	Glycosyl transferase (Group 1
HPT03_RS16315	ENOG4105W0E	50S ribosomal protein L33
HPT03_RS16320	ENOG4105KDC	50s ribosomal protein l28
HPT03_RS16325	ENOG4105W5Q	DNA repair protein (RadC
HPT03_RS16330	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HPT03_RS16335	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HPT03_RS16340	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HPT03_RS16345	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HPT03_RS16350	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HPT03_RS16355	ENOG4105DSJ	YicC domain protein
HPT03_RS16375	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPT03_RS16395	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPT03_RS16400	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HPT03_RS16405	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPT03_RS16410	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HPT03_RS16415	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HPT03_RS16420	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HPT03_RS16425	ENOG4105VG0	50S ribosomal protein l34
HPT03_RS16430	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HPT03_RS16435	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HPT03_RS16440	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPT03_RS16445	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HPT03_RS16455	ENOG4105CAF	HipA N-terminal domain protein
HPT03_RS16460	ENOG4108UQ5	membrane protein YcdZ
HPT03_RS16475	ENOG41067XB	TonB family
HPT03_RS16495	ENOG4106P55	Transcriptional regulator
HPT03_RS16515	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HPT03_RS16525	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HPT03_RS16530	ENOG4108MG3	formate dehydrogenase
HPT03_RS16535	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HPT03_RS16540	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HPT03_RS16545	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HPT03_RS16550	ENOG4107T7U	Sulfatase
HPT03_RS16555	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HPT03_RS16560	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HPT03_RS16565	ENOG4105BZU	Histidine kinase
HPT03_RS16575	ENOG4105EJG	cellulose synthase
HPT03_RS16585	ENOG4107QZ7	Cellulose synthase catalytic subunit
HPT03_RS16595	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HPT03_RS16605	ENOG4105H4F	exported protein
HPT03_RS16630	ENOG4105E6S	usher protein(
HPT03_RS16675	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HPT03_RS16700	ENOG4105D7V	transposase
HPT03_RS16705	ENOG4108RS6	transposase
HPT03_RS16710	ENOG41080HI	glycine oxidase
HPT03_RS16715	ENOG4105C4Y	ABC transporter
HPT03_RS16725	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPT03_RS16780	ENOG4105EMU	Dehydrogenase
HPT03_RS16785	ENOG4108BUD	transposase
HPT03_RS16845	ENOG4108BUD	transposase
HPT03_RS16860	ENOG4105EUV	Phenol 2-monooxygenase
HPT03_RS16910	ENOG4108BUD	transposase
HPT03_RS16965	ENOG4105EKQ	RNA-directed DNA polymerase
HPT03_RS17015	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HPT03_RS17020	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPT03_RS17025	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HPT03_RS17030	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HPT03_RS17035	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HPT03_RS17040	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HPT03_RS17045	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPT03_RS17050	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPT03_RS17055	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPT03_RS17060	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HPT03_RS17065	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
HPT03_RS17070	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HPT03_RS17075	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HPT03_RS17080	ENOG4105QTB	Flavodoxin
HPT03_RS17085	ENOG4108VVK	transcriptional Regulator, AsnC
HPT03_RS17090	ENOG4105CU9	asparagine synthetase A
HPT03_RS17095	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HPT03_RS17100	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
HPT03_RS17105	ENOG4108RVA	ribokinase
HPT03_RS17110	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPT03_RS17115	ENOG4107EJG	GntR family transcriptional regulator
HPT03_RS17140	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HPT03_RS17145	ENOG4107QR9	Iron-sulfur cluster binding protein
HPT03_RS17150	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HPT03_RS17155	ENOG4105DIJ	Phosphoethanolamine transferase
HPT03_RS17160	ENOG4107QN1	sodium solute
HPT03_RS17165	ENOG41062QD	Membrane
HPT03_RS17170	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HPT03_RS17175	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HPT03_RS17180	ENOG4108RPX	mosc domain containing protein
HPT03_RS17185	ENOG4108RS6	transposase
HPT03_RS17190	ENOG4105D7V	transposase
HPT03_RS17195	ENOG4105C31	Tryptophanyl-tRNA synthetase
HPT03_RS17200	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HPT03_RS17205	ENOG4105DJV	ribulose-phosphate 3-epimerase
HPT03_RS17220	ENOG4105D49	3-dehydroquinate synthase
HPT03_RS17225	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPT03_RS17230	ENOG4105E4G	Type IV pilus
HPT03_RS17250	ENOG4108JQC	penicillin-binding protein 1A
HPT03_RS17255	ENOG4105D01	(LipO)protein
HPT03_RS17260	ENOG4107RK2	ADP-ribose diphosphatase NudE
HPT03_RS17265	ENOG4105DQY	intracellular growth attenuator
HPT03_RS17270	ENOG4105VEJ	Heat shock protein
HPT03_RS17275	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HPT03_RS17280	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HPT03_RS17285	ENOG4105C2I	pirin domain protein
HPT03_RS17295	ENOG4105CBX	hi0933 family
HPT03_RS17300	ENOG4105CJ3	phosphate transporter
HPT03_RS17305	ENOG4108V6B	universal stress protein B
HPT03_RS17310	ENOG4108M6U	Universal stress protein A
HPT03_RS17315	ENOG4105D82	Glutamate dehydrogenase
HPT03_RS17320	ENOG4108R85	Short chain dehydrogenase
HPT03_RS17325	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HPT03_RS17330	ENOG4105DGW	oligopeptidase A
HPT03_RS17370	ENOG4108N3D	putative enzyme
HPT03_RS17375	ENOG4106PYX	Receptor
HPT03_RS17410	ENOG4105CS6	Rhs element vgr protein
HPT03_RS17415	ENOG4108WC9	type VI secretion system effector, hcp1 family
HPT03_RS17420	ENOG4105N1F	Hnh endonuclease
HPT03_RS17425	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HPT03_RS17430	ENOG4105D3G	Pseudouridine synthase
HPT03_RS17440	ENOG4108Q3X	Transcriptional regulator
HPT03_RS17445	ENOG4105CI1	PTS System
HPT03_RS17455	ENOG4105C8J	)-transporter
HPT03_RS17460	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HPT03_RS17470	ENOG4105EXC	Acyl-transferase
HPT03_RS17475	ENOG4105KT7	mgtC SapB transporter
HPT03_RS17480	ENOG4105EAA	nucleoside
HPT03_RS17490	ENOG4105ETE	Transcriptional regulator (LacI family
HPT03_RS17495	ENOG4107KGK	dmso reductase anchor subunit
HPT03_RS17500	ENOG4105QAX	Iron-sulfur
HPT03_RS17505	ENOG4107QY8	reductase
HPT03_RS17515	ENOG4105D5Q	Arginine ornithine antiporter
HPT03_RS17520	ENOG4105CXN	decarboxylase
HPT03_RS17525	ENOG4105D5Q	Arginine ornithine antiporter
HPT03_RS17540	ENOG4108IPW	abc transporter atp-binding protein
HPT03_RS17545	ENOG4105CM4	permease protein
HPT03_RS17550	ENOG4105DHS	permease protein
HPT03_RS17560	ENOG4105VZJ	PTS System
HPT03_RS17565	ENOG4105CK1	PTS System
HPT03_RS17570	ENOG4105VCP	PTS System
HPT03_RS17575	ENOG4105EZV	Transcriptional regulator
HPT03_RS17580	ENOG4105F8D	glycoside hydrolase family 4
HPT03_RS17585	ENOG410901P	UPF0249 protein
HPT03_RS17590	ENOG4108T1M	outer membrane protein x
HPT03_RS17600	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPT03_RS17605	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HPT03_RS17610	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS17625	ENOG4108S9F	abc transporter, atp-binding protein
HPT03_RS17645	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPT03_RS17655	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HPT03_RS17680	ENOG4105SYT	Methylenetetrahydrofolate reductase
HPT03_RS17685	ENOG4105K78	MarR family Transcriptional regulator
HPT03_RS17690	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HPT03_RS17695	ENOG4105E98	transcriptional regulator DeoR family
HPT03_RS17700	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HPT03_RS17705	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HPT03_RS17710	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HPT03_RS17715	ENOG4105MJ2	Competence protein
HPT03_RS17720	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HPT03_RS17730	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
HPT03_RS17735	ENOG4105CE1	Ferrous iron transport protein b
HPT03_RS17740	ENOG4105XFK	Ferrous iron transport protein A
HPT03_RS17760	ENOG4105D9U	N-acetyltransferase
HPT03_RS17765	ENOG4105C7N	Xanthine uracil vitamin C permease
HPT03_RS17775	ENOG41081XD	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HPT03_RS17780	ENOG4105CHR	reductase
HPT03_RS17785	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HPT03_RS17790	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HPT03_RS17795	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPT03_RS17800	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HPT03_RS17815	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPT03_RS17840	ENOG4105DRP	amino acid AbC transporter
HPT03_RS17845	ENOG4105E5Q	amino acid AbC transporter
HPT03_RS17850	ENOG4105CT1	(ABC) transporter
HPT03_RS17855	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HPT03_RS17865	ENOG4105E2Z	phosphate ABC transporter (Permease
HPT03_RS17870	ENOG4105C8U	phosphate abc transporter
HPT03_RS17875	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HPT03_RS17880	ENOG4105E0F	Histidine kinase
HPT03_RS17890	ENOG4108RRZ	Transcription elongation factor GreB
HPT03_RS17895	ENOG4105BZM	domain protein
HPT03_RS17900	ENOG4106B0W	Curli production assembly transport component CsgG
HPT03_RS17910	ENOG4107Y60	(LipO)protein
HPT03_RS17915	ENOG4105D4P	Coproporphyrinogen iii oxidase
HPT03_RS17935	ENOG4105CI3	gtp-binding protein typa
HPT03_RS17940	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
HPT03_RS17945	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HPT03_RS17950	ENOG4105SUU	thioesterase domain
HPT03_RS17955	ENOG4105FE9	pseudouridine synthase
HPT03_RS17965	ENOG4105JV1	AsmA family
HPT03_RS17970	ENOG4105C2W	permease
HPT03_RS17975	ENOG4105D6U	Sodium Glutamate Symporter
HPT03_RS17980	ENOG4105CB5	ATP-dependent DNA helicase recG
HPT03_RS17985	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HPT03_RS17990	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HPT03_RS17995	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HPT03_RS18000	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HPT03_RS18005	ENOG4105EN6	Membrane
HPT03_RS18010	ENOG4105D99	atp gtp-binding protein
HPT03_RS18025	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HPT03_RS18030	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HPT03_RS18035	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HPT03_RS18045	ENOG4105CW0	outer membrane usher protein
HPT03_RS18070	ENOG4108NAE	Fimbrial chaperone protein
HPT03_RS18080	ENOG4105D0C	transport protein
HPT03_RS18085	ENOG4105R2A	(LipO)protein
HPT03_RS18100	ENOG4105D5K	Hemolysin activator protein
HPT03_RS18105	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPT03_RS18110	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS18115	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPT03_RS18120	ENOG4105C3U	ABC transporter
HPT03_RS18125	ENOG4108JQ7	(ABC) transporter
HPT03_RS18135	ENOG4105BZU	Histidine kinase
HPT03_RS18140	ENOG4105CS0	peptidase
HPT03_RS18145	ENOG4105VSH	4-oxalocrotonate tautomerase
HPT03_RS18150	ENOG4107H3J	ribonuclease
HPT03_RS18160	ENOG4105D6S	protein involved in catabolism of external DNA
HPT03_RS18165	ENOG4105DC8	reductase
HPT03_RS18170	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPT03_RS18180	ENOG4105CG3	alpha amylase, catalytic region
HPT03_RS18185	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HPT03_RS18190	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HPT03_RS18195	ENOG4105PC1	Conserved Protein
HPT03_RS18200	ENOG4105E27	serine threonine protein kinase
HPT03_RS18205	ENOG4108Z33	Thiol disulfide Interchange Protein
HPT03_RS18215	ENOG4105C2M	dna polymerase I
HPT03_RS18220	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HPT03_RS18230	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HPT03_RS18240	ENOG4105C8Y	Acetylornithine aminotransferase
HPT03_RS18250	ENOG4108UKZ	OsmC family
HPT03_RS18255	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HPT03_RS18260	ENOG4105YP7	UPF0270 protein
HPT03_RS18265	ENOG4105DNZ	Alpha Beta Hydrolase
HPT03_RS18275	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
HPT03_RS18280	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HPT03_RS18285	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS18290	ENOG4105C8Q	Methyl-accepting chemotaxis
HPT03_RS18295	ENOG4105C5H	ABC transporter
HPT03_RS18300	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HPT03_RS18310	ENOG4105VKU	nucleicacid-binding protein
HPT03_RS18315	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HPT03_RS18320	ENOG4105VRX	Protein slyX homolog
HPT03_RS18325	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HPT03_RS18335	ENOG4105WWK	YheO domain protein
HPT03_RS18340	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HPT03_RS18345	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HPT03_RS18355	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HPT03_RS18360	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HPT03_RS18365	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HPT03_RS18370	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HPT03_RS18375	ENOG4105PM1	preprotein translocase subunit SecE
HPT03_RS18380	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HPT03_RS18385	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HPT03_RS18390	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HPT03_RS18395	ENOG4108VZM	50s ribosomal protein L10
HPT03_RS18400	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HPT03_RS18405	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPT03_RS18410	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPT03_RS18415	ENOG4105DNE	Transposase
HPT03_RS18420	ENOG4105D41	biosynthesis protein thiH
HPT03_RS18425	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HPT03_RS18430	ENOG4105WHD	thiamine biosynthesis protein ThiS
HPT03_RS18435	ENOG4105D06	uba thif-type nad fad binding protein
HPT03_RS18440	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HPT03_RS18445	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HPT03_RS18455	ENOG4105E09	nadh pyrophosphatase
HPT03_RS18460	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HPT03_RS18465	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HPT03_RS18470	ENOG4105R2J	Conserved Protein
HPT03_RS18480	ENOG4108T8B	Protein of unknown function (DUF1481)
HPT03_RS18485	ENOG4105C12	Phosphoribosylglycinamide synthetase
HPT03_RS18490	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HPT03_RS18530	ENOG4105CVG	Homoserine O-transsuccinylase
HPT03_RS18535	ENOG4107QP3	malate synthase g
HPT03_RS18540	ENOG4108I9X	Isocitrate lyase
HPT03_RS18550	ENOG4108UHU	Aldolase
HPT03_RS18555	ENOG4105C01	Dihydroxy-acid dehydratase
HPT03_RS18560	ENOG41069M3	Transcriptional regulator
HPT03_RS18565	ENOG4105C3R	Methionine synthase
HPT03_RS18580	ENOG4105CFH	Aspartokinase
HPT03_RS18585	ENOG4107QP8	phosphohexose isomerase
HPT03_RS18590	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HPT03_RS18595	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HPT03_RS18600	ENOG4105E55	glycerol-3-phosphate acyltransferase
HPT03_RS18605	ENOG41080IJ	Diacylglycerol kinase
HPT03_RS18610	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HPT03_RS18615	ENOG4105MYN	Zinc uptake regulation protein
HPT03_RS18620	ENOG4108UUM	single-stranded DNA-binding protein
HPT03_RS18625	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HPT03_RS18630	ENOG4105C44	Serine transporter
HPT03_RS18640	ENOG4105CGF	Aromatic amino acid aminotransferase
HPT03_RS18645	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPT03_RS18650	ENOG4105CDU	Replicative dna helicase
HPT03_RS18655	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HPT03_RS18660	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HPT03_RS18680	ENOG4105D38	putrescine abc transporter
HPT03_RS18685	ENOG4108HM4	ABC transporter
HPT03_RS18700	ENOG4108SQA	Fimbrial
HPT03_RS18705	ENOG4105CW0	outer membrane usher protein
HPT03_RS18710	ENOG4108AF8	Chaperone
HPT03_RS18715	ENOG4108WDE	Fimbrial protein
HPT03_RS18745	ENOG4105KNY	Microcompartments protein