locus-tag	class	description
IM703_RS00030	COG0542	response to heat
IM703_RS00035	COG1496	oxidoreductase activity
IM703_RS00040	COG0564	pseudouridine synthase activity
IM703_RS00045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM703_RS00050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM703_RS00055	COG1605	Chorismate mutase
IM703_RS00055	COG0077	Prephenate dehydratase
IM703_RS00060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IM703_RS00070	COG0287	Prephenate dehydrogenase
IM703_RS00070	COG1605	Chorismate mutase
IM703_RS00075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM703_RS00080	COG0335	large ribosomal subunit rRNA binding
IM703_RS00085	COG0336	Belongs to the RNA methyltransferase TrmD family
IM703_RS00095	COG0228	four-way junction DNA binding
IM703_RS00100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IM703_RS00105	COG4137	Cytochrome C assembly protein
IM703_RS00110	COG4536	flavin adenine dinucleotide binding
IM703_RS00120	COG1854	S-ribosylhomocysteine lyase activity
IM703_RS00125	COG2918	glutathione biosynthetic process
IM703_RS00155	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IM703_RS00160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IM703_RS00170	COG1546	Belongs to the CinA family
IM703_RS00175	COG2814	Major facilitator Superfamily
IM703_RS00180	COG0204	Acyl-transferase
IM703_RS00180	COG0318	PFAM AMP-dependent synthetase and ligase
IM703_RS00185	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM703_RS00190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM703_RS00195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM703_RS00205	COG1073	alpha beta
IM703_RS00210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IM703_RS00215	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM703_RS00220	COG4774	siderophore transport
IM703_RS00225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM703_RS00235	COG3237	CsbD-like
IM703_RS00240	COG2991	Protein conserved in bacteria
IM703_RS00245	COG1477	protein flavinylation
IM703_RS00250	COG2871	sodium ion transport
IM703_RS00255	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM703_RS00260	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM703_RS00265	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM703_RS00270	COG1805	sodium ion transport
IM703_RS00275	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM703_RS00280	COG3034	peptidoglycan biosynthetic process
IM703_RS00285	COG0121	glutamine amidotransferase
IM703_RS00290	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM703_RS00295	COG1960	acyl-CoA dehydrogenase activity
IM703_RS00305	COG0583	DNA-binding transcription factor activity
IM703_RS00310	COG0583	DNA-binding transcription factor activity
IM703_RS00330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IM703_RS00335	COG0189	ligase activity
IM703_RS00340	COG1678	Uncharacterized ACR, COG1678
IM703_RS00345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IM703_RS00350	COG2805	Type II/IV secretion system protein
IM703_RS00355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IM703_RS00360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM703_RS00365	COG0762	integral membrane protein
IM703_RS00370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM703_RS00375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM703_RS00380	COG4607	ABC-type enterochelin transport system periplasmic component
IM703_RS00390	COG2066	Belongs to the glutaminase family
IM703_RS00395	COG3171	Protein conserved in bacteria
IM703_RS00405	COG1194	a g-specific adenine glycosylase
IM703_RS00410	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IM703_RS00415	COG0741	lytic transglycosylase activity
IM703_RS00470	COG2211	Major facilitator Superfamily
IM703_RS00500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IM703_RS00515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM703_RS00530	COG3539	Fimbrial protein
IM703_RS00550	COG3188	usher protein
IM703_RS00560	COG3539	Fimbrial protein
IM703_RS00565	COG0582	viral genome integration into host DNA
IM703_RS00570	COG1690	Belongs to the RtcB family
IM703_RS00580	COG4650	regulator
IM703_RS00585	COG1234	tRNA 3'-trailer cleavage
IM703_RS00600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM703_RS00605	COG1846	Transcriptional regulator
IM703_RS00620	COG2314	TM2 domain
IM703_RS00630	COG0126	phosphoglycerate kinase activity
IM703_RS00635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM703_RS00640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM703_RS00695	COG0328	RNA-DNA hybrid ribonuclease activity
IM703_RS00700	COG2226	methyltransferase
IM703_RS00705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM703_RS00710	COG1388	LysM domain
IM703_RS00710	COG0741	lytic transglycosylase activity
IM703_RS00715	COG0471	metal ion transport
IM703_RS00720	COG0148	phosphopyruvate hydratase activity
IM703_RS00725	COG0504	CTP synthase activity
IM703_RS00730	COG3956	TIGRFAM MazG family protein
IM703_RS00745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM703_RS00750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM703_RS00760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM703_RS00800	COG3501	Rhs element vgr protein
IM703_RS00810	COG0316	Belongs to the HesB IscA family
IM703_RS00815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM703_RS00820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM703_RS00825	COG1643	Atp-dependent helicase
IM703_RS00830	COG1489	DNA binding
IM703_RS00840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM703_RS00845	COG0617	tRNA 3'-terminal CCA addition
IM703_RS00850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM703_RS00855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM703_RS00860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM703_RS00865	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IM703_RS00885	COG1840	ABC-type Fe3 transport system, periplasmic component
IM703_RS00895	COG3842	ATPase activity
IM703_RS00900	COG3048	D-serine ammonia-lyase activity
IM703_RS00905	COG2610	gluconate transmembrane transporter activity
IM703_RS00910	COG0583	DNA-binding transcription factor activity
IM703_RS00925	COG0754	glutathionylspermidine amidase activity
IM703_RS00940	COG4633	Protein conserved in bacteria
IM703_RS00955	COG2837	iron assimilation
IM703_RS00965	COG0243	molybdopterin cofactor binding
IM703_RS00970	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS00985	COG0501	Belongs to the peptidase M48B family
IM703_RS00995	COG0477	Major facilitator Superfamily
IM703_RS01000	COG0842	Transport permease protein
IM703_RS01005	COG1131	(ABC) transporter
IM703_RS01010	COG0288	reversible hydration of carbon dioxide
IM703_RS01015	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IM703_RS01020	COG2132	Multicopper oxidase
IM703_RS01060	COG5441	Belongs to the UPF0261 family
IM703_RS01065	COG5564	TIM-barrel signal transduction protein
IM703_RS01070	COG0673	inositol 2-dehydrogenase activity
IM703_RS01075	COG0534	Mate efflux family protein
IM703_RS01090	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM703_RS01095	COG3069	C4-dicarboxylate transmembrane transporter activity
IM703_RS01105	COG0523	cobalamin synthesis protein
IM703_RS01110	COG2879	small protein
IM703_RS01115	COG1966	Carbon starvation protein
IM703_RS01135	COG4245	von Willebrand factor, type A
IM703_RS01140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM703_RS01145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM703_RS01155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM703_RS01170	COG3264	Mechanosensitive ion channel
IM703_RS01170	COG1196	nuclear chromosome segregation
IM703_RS01175	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IM703_RS01180	COG1309	transcriptional regulator
IM703_RS01185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM703_RS01190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM703_RS01210	COG1946	Acyl-CoA thioesterase
IM703_RS01215	COG0004	ammonium transporteR
IM703_RS01220	COG0347	Belongs to the P(II) protein family
IM703_RS01225	COG1132	(ABC) transporter
IM703_RS01230	COG1132	(ABC) transporter
IM703_RS01235	COG1522	sequence-specific DNA binding
IM703_RS01240	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IM703_RS01245	COG0824	Thioesterase
IM703_RS01250	COG1555	photosystem II stabilization
IM703_RS01250	COG1596	polysaccharide export
IM703_RS01255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM703_RS01260	COG0776	regulation of translation
IM703_RS01265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM703_RS01270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM703_RS01275	COG0740	serine-type endopeptidase activity
IM703_RS01280	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM703_RS01285	COG0271	Belongs to the BolA IbaG family
IM703_RS01290	COG3056	Lipoprotein
IM703_RS01295	COG2223	nitrite transmembrane transporter activity
IM703_RS01300	COG0513	Belongs to the DEAD box helicase family
IM703_RS01310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM703_RS01315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM703_RS01320	COG1845	cytochrome c oxidase, subunit III
IM703_RS01325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IM703_RS01330	COG0109	protoheme IX farnesyltransferase activity
IM703_RS01335	COG2814	Major facilitator Superfamily
IM703_RS01340	COG1666	GTP binding
IM703_RS01345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM703_RS01355	COG0301	tRNA thio-modification
IM703_RS01355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM703_RS01360	COG1722	exodeoxyribonuclease VII activity
IM703_RS01365	COG0142	geranyltranstransferase activity
IM703_RS01370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM703_RS01375	COG1869	D-ribose catabolic process
IM703_RS01380	COG1129	ABC transporter
IM703_RS01385	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM703_RS01395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM703_RS01400	COG1609	Transcriptional regulator
IM703_RS01405	COG2824	Alkylphosphonate utilization operon protein PhnA
IM703_RS01410	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IM703_RS01415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM703_RS01420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IM703_RS01425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM703_RS01425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM703_RS01430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM703_RS01435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM703_RS01440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM703_RS01445	COG1862	Preprotein translocase
IM703_RS01450	COG0343	queuine tRNA-ribosyltransferase activity
IM703_RS01455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IM703_RS01460	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IM703_RS01465	COG0450	alkyl hydroperoxide reductase
IM703_RS01475	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS01480	COG2414	aldehyde ferredoxin oxidoreductase
IM703_RS01490	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS01495	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IM703_RS01515	COG1114	Component of the transport system for branched-chain amino acids
IM703_RS01520	COG5002	protein histidine kinase activity
IM703_RS01530	COG0420	3'-5' exonuclease activity
IM703_RS01535	COG0419	ATPase involved in DNA repair
IM703_RS01550	COG3719	Belongs to the RNase T2 family
IM703_RS01555	COG0737	Belongs to the 5'-nucleotidase family
IM703_RS01565	COG2974	May be involved in recombination
IM703_RS01570	COG0425	Belongs to the sulfur carrier protein TusA family
IM703_RS01575	COG2391	methyltransferase activity
IM703_RS01580	COG0309	Hydrogenase expression formation protein (HypE)
IM703_RS01585	COG0409	Hydrogenase expression formation protein
IM703_RS01590	COG0298	carbon dioxide binding
IM703_RS01595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM703_RS01600	COG1773	rubredoxin
IM703_RS01605	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IM703_RS01610	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IM703_RS01615	COG5557	Pfam Polysulphide reductase, NrfD
IM703_RS01620	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS01625	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
IM703_RS01635	COG0848	biopolymer transport protein
IM703_RS01640	COG0811	peptide transport
IM703_RS01645	COG0626	cystathionine gamma-synthase activity
IM703_RS01655	COG2226	methyltransferase
IM703_RS01660	COG1979	alcohol dehydrogenase
IM703_RS01665	COG0656	L-ascorbic acid biosynthetic process
IM703_RS01670	COG1388	LysM domain
IM703_RS01670	COG1470	cell adhesion involved in biofilm formation
IM703_RS01695	COG1132	(ABC) transporter
IM703_RS01700	COG2375	cellular response to nickel ion
IM703_RS01700	COG1132	(ABC) transporter
IM703_RS01715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM703_RS01725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM703_RS01730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM703_RS01735	COG1047	Peptidyl-prolyl cis-trans
IM703_RS01740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IM703_RS01745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM703_RS01750	COG0196	riboflavin kinase activity
IM703_RS01755	COG0268	Binds directly to 16S ribosomal RNA
IM703_RS01760	COG0583	DNA-binding transcription factor activity
IM703_RS01765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM703_RS01775	COG0484	heat shock protein binding
IM703_RS01780	COG0443	Heat shock 70 kDa protein
IM703_RS01785	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM703_RS01795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM703_RS01800	COG3022	response to hydroperoxide
IM703_RS01815	COG0083	homoserine kinase activity
IM703_RS01825	COG0745	RESPONSE REGULATOR receiver
IM703_RS01830	COG3045	CreA protein
IM703_RS01835	COG2207	Transcriptional regulator
IM703_RS01835	COG3708	Transcriptional regulator
IM703_RS01840	COG0406	alpha-ribazole phosphatase activity
IM703_RS01845	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IM703_RS01850	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IM703_RS01860	COG0488	(ABC) transporter
IM703_RS01870	COG1595	DNA-templated transcription, initiation
IM703_RS01880	COG4771	TonB-dependent receptor
IM703_RS01885	COG4178	(ABC) transporter
IM703_RS01890	COG0612	Peptidase, M16
IM703_RS01900	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM703_RS01900	COG1902	pentaerythritol trinitrate reductase activity
IM703_RS01905	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IM703_RS01910	COG0586	Pfam SNARE associated Golgi protein
IM703_RS01915	COG4575	ribosome binding
IM703_RS01920	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
IM703_RS01930	COG2259	Doxx family
IM703_RS01935	COG0583	DNA-binding transcription factor activity
IM703_RS01940	COG1741	Belongs to the pirin family
IM703_RS01950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IM703_RS01960	COG0792	nuclease activity
IM703_RS01965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM703_RS01970	COG2823	Periplasmic or secreted lipoprotein
IM703_RS01975	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM703_RS01980	COG0830	nickel cation binding
IM703_RS01985	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IM703_RS01995	COG0832	Belongs to the urease beta subunit family
IM703_RS02005	COG0829	nickel cation binding
IM703_RS02010	COG2207	Transcriptional regulator
IM703_RS02015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM703_RS02020	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IM703_RS02025	COG0784	Response regulator, receiver
IM703_RS02025	COG2198	Histidine kinase
IM703_RS02025	COG5002	protein histidine kinase activity
IM703_RS02030	COG0069	glutamate synthase activity
IM703_RS02030	COG0070	glutamate synthase
IM703_RS02030	COG0067	glutamate synthase
IM703_RS02035	COG0493	'glutamate synthase
IM703_RS02040	COG3069	C4-dicarboxylate transmembrane transporter activity
IM703_RS02045	COG1473	amidohydrolase
IM703_RS02050	COG2969	positive regulation of protein catabolic process
IM703_RS02055	COG0625	glutathione transferase activity
IM703_RS02060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IM703_RS02065	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM703_RS02070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IM703_RS02075	COG3105	Protein conserved in bacteria
IM703_RS02080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM703_RS02085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM703_RS02100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM703_RS02105	COG5007	Belongs to the BolA IbaG family
IM703_RS02115	COG2854	intermembrane phospholipid transfer
IM703_RS02120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM703_RS02125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM703_RS02130	COG1127	ABC transporter
IM703_RS02135	COG0530	calcium, potassium:sodium antiporter activity
IM703_RS02140	COG0517	IMP dehydrogenase activity
IM703_RS02140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IM703_RS02145	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IM703_RS02150	COG3117	lipopolysaccharide transmembrane transporter activity
IM703_RS02155	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IM703_RS02160	COG1137	ATPase activity
IM703_RS02165	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IM703_RS02170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM703_RS02180	COG1660	Displays ATPase and GTPase activities
IM703_RS02185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM703_RS02190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM703_RS02195	COG0312	modulator of DNA gyrase
IM703_RS02200	COG3028	Belongs to the UPF0307 family
IM703_RS02215	COG0312	modulator of DNA gyrase
IM703_RS02220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM703_RS02225	COG3164	Protein of unknown function
IM703_RS02230	COG1530	ribonuclease E activity
IM703_RS02240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IM703_RS02245	COG1792	Involved in formation and maintenance of cell shape
IM703_RS02250	COG1077	Cell shape determining protein MreB Mrl
IM703_RS02255	COG0604	alcohol dehydrogenase
IM703_RS02260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM703_RS02265	COG0511	ligase activity, forming carbon-carbon bonds
IM703_RS02270	COG0439	Biotin carboxylase
IM703_RS02275	COG1522	sequence-specific DNA binding
IM703_RS02280	COG0814	amino acid
IM703_RS02285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM703_RS02290	COG3924	membrane
IM703_RS02295	COG4145	pantothenate transmembrane transporter activity
IM703_RS02300	COG2264	protein methyltransferase activity
IM703_RS02305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM703_RS02310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IM703_RS02335	COG2807	transmembrane transport
IM703_RS02340	COG0549	Belongs to the carbamate kinase family
IM703_RS02345	COG0584	glycerophosphoryl diester phosphodiesterase
IM703_RS02350	COG1653	transport
IM703_RS02355	COG1175	transmembrane transport
IM703_RS02360	COG0395	ABC-type sugar transport system, permease component
IM703_RS02365	COG3842	ATPase activity
IM703_RS02370	COG0501	Belongs to the peptidase M48B family
IM703_RS02375	COG1846	Transcriptional regulator
IM703_RS02380	COG2814	Major facilitator Superfamily
IM703_RS02385	COG0456	acetyltransferase
IM703_RS02390	COG1929	Belongs to the glycerate kinase type-1 family
IM703_RS02400	COG2177	Part of the ABC transporter FtsEX involved in
IM703_RS02405	COG2884	Cell division ATP-binding protein ftsE
IM703_RS02410	COG0552	protein localization to endoplasmic reticulum
IM703_RS02415	COG0742	ribosomal rna small subunit methyltransferase
IM703_RS02420	COG3776	membrane
IM703_RS02430	COG3714	YhhN family
IM703_RS02435	COG2217	Heavy metal translocating P-type atpase
IM703_RS02440	COG0425	Belongs to the sulfur carrier protein TusA family
IM703_RS02445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IM703_RS02460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM703_RS02465	COG0247	lactate metabolic process
IM703_RS02475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM703_RS02480	COG2271	Major facilitator Superfamily
IM703_RS02485	COG0584	glycerophosphoryl diester phosphodiesterase
IM703_RS02510	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IM703_RS02515	COG1053	succinate dehydrogenase
IM703_RS02520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM703_RS02525	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IM703_RS02530	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IM703_RS02535	COG3177	Filamentation induced by cAMP protein fic
IM703_RS02540	COG2076	Multidrug Resistance protein
IM703_RS02545	COG0298	carbon dioxide binding
IM703_RS02550	COG0375	protein maturation
IM703_RS02555	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IM703_RS02560	COG3604	Transcriptional regulator
IM703_RS02570	COG1737	Transcriptional regulator
IM703_RS02580	COG1263	PTS System
IM703_RS02580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM703_RS02590	COG2194	sulfuric ester hydrolase activity
IM703_RS02605	COG1304	FMN binding
IM703_RS02610	COG1335	isochorismatase
IM703_RS02615	COG2181	nitrate reductase activity
IM703_RS02620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IM703_RS02625	COG1140	nitrate reductase beta subunit
IM703_RS02630	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IM703_RS02635	COG2223	nitrite transmembrane transporter activity
IM703_RS02640	COG3850	Histidine kinase
IM703_RS02645	COG2197	response regulator
IM703_RS02650	COG0583	DNA-binding transcription factor activity
IM703_RS02665	COG0730	response to heat
IM703_RS02670	COG4770	biotin carboxylase activity
IM703_RS02675	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IM703_RS02680	COG4336	lyase activity
IM703_RS02685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IM703_RS02690	COG1914	H( )-stimulated, divalent metal cation uptake system
IM703_RS02720	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IM703_RS02725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM703_RS02730	COG1739	Uncharacterized protein family UPF0029
IM703_RS02735	COG0006	proline dipeptidase activity
IM703_RS02740	COG1024	Enoyl-CoA hydratase
IM703_RS02740	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM703_RS02745	COG0183	Belongs to the thiolase family
IM703_RS02755	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM703_RS02770	COG0805	protein transport
IM703_RS02775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM703_RS02780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM703_RS02790	COG3165	ubiquinone biosynthetic process from chorismate
IM703_RS02795	COG2226	methyltransferase
IM703_RS02800	COG1322	Protein conserved in bacteria
IM703_RS02805	COG0586	Pfam SNARE associated Golgi protein
IM703_RS02810	COG2365	Tyrosine phosphatase family
IM703_RS02820	COG3753	Protein conserved in bacteria
IM703_RS02830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM703_RS02835	COG0583	DNA-binding transcription factor activity
IM703_RS02845	COG0025	NhaP-type Na H and K H
IM703_RS02850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM703_RS02855	COG2252	PERMEase
IM703_RS02860	COG2814	Major facilitator Superfamily
IM703_RS02875	COG0440	acetolactate synthase activity
IM703_RS02880	COG0028	Belongs to the TPP enzyme family
IM703_RS02890	COG1288	antiporter activity
IM703_RS02900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM703_RS02920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM703_RS02920	COG1263	PTS System
IM703_RS02925	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM703_RS02935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IM703_RS02940	COG1349	DNA-binding transcription factor activity
IM703_RS02945	COG1690	Belongs to the RtcB family
IM703_RS02950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IM703_RS02955	COG2271	Major facilitator Superfamily
IM703_RS02960	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IM703_RS02970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM703_RS02975	COG3829	transcription factor binding
IM703_RS02990	COG3188	usher protein
IM703_RS03055	COG3596	GTP binding
IM703_RS03080	COG3423	Transcriptional regulator
IM703_RS03130	COG0582	viral genome integration into host DNA
IM703_RS03140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM703_RS03145	COG0795	lipopolysaccharide-transporting ATPase activity
IM703_RS03150	COG0795	lipopolysaccharide-transporting ATPase activity
IM703_RS03155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM703_RS03160	COG2927	DNA polymerase III (CHI subunit)
IM703_RS03165	COG0525	valine-tRNA ligase activity
IM703_RS03170	COG0456	acetyltransferase
IM703_RS03190	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IM703_RS03195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM703_RS03205	COG0540	Belongs to the ATCase OTCase family
IM703_RS03210	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IM703_RS03215	COG0251	oxidation-reduction process
IM703_RS03225	COG0602	queuosine metabolic process
IM703_RS03250	COG2827	Endonuclease containing a URI domain
IM703_RS03255	COG3153	acetyltransferase
IM703_RS03260	COG3154	lipid carrier protein
IM703_RS03265	COG0826	peptidase U32
IM703_RS03270	COG0826	peptidase U32
IM703_RS03290	COG3275	phosphorelay sensor kinase activity
IM703_RS03315	COG0513	Belongs to the DEAD box helicase family
IM703_RS03325	COG1185	polyribonucleotide nucleotidyltransferase activity
IM703_RS03330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IM703_RS03335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM703_RS03340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM703_RS03345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM703_RS03350	COG0195	Participates in both transcription termination and antitermination
IM703_RS03355	COG0779	Required for maturation of 30S ribosomal subunits
IM703_RS03370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM703_RS03375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM703_RS03380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM703_RS03390	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IM703_RS03395	COG1534	Rna-binding protein
IM703_RS03405	COG2027	D-alanyl-D-alanine carboxypeptidase
IM703_RS03410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM703_RS03415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM703_RS03420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM703_RS03425	COG0142	geranyltranstransferase activity
IM703_RS03440	COG3423	Transcriptional regulator
IM703_RS03445	COG0039	L-malate dehydrogenase activity
IM703_RS03450	COG1438	arginine binding
IM703_RS03455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM703_RS03460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IM703_RS03465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IM703_RS03485	COG2105	PFAM AIG2 family protein
IM703_RS03490	COG2911	Protein conserved in bacteria
IM703_RS03495	COG0729	surface antigen
IM703_RS03500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM703_RS03505	COG1253	flavin adenine dinucleotide binding
IM703_RS03515	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IM703_RS03525	COG0545	Peptidyl-prolyl cis-trans isomerase
IM703_RS03530	COG1012	belongs to the aldehyde dehydrogenase family
IM703_RS03535	COG3443	Belongs to the bacterial solute-binding protein 9 family
IM703_RS03540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM703_RS03545	COG0254	rRNA binding
IM703_RS03560	COG0359	binds to the 23S rRNA
IM703_RS03565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IM703_RS03570	COG2965	DNA replication, synthesis of RNA primer
IM703_RS03575	COG0360	Binds together with S18 to 16S ribosomal RNA
IM703_RS03580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM703_RS03585	COG0557	exoribonuclease II activity
IM703_RS03590	COG1959	2 iron, 2 sulfur cluster binding
IM703_RS03595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM703_RS03605	COG0330	HflC and HflK could
IM703_RS03610	COG0330	HflC and HflK could
IM703_RS03615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM703_RS03620	COG1923	regulation of RNA biosynthetic process
IM703_RS03625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM703_RS03630	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IM703_RS03635	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM703_RS03640	COG0802	atpase or kinase
IM703_RS03645	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IM703_RS03665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IM703_RS03670	COG1162	GTPase activity
IM703_RS03675	COG0688	phosphatidylethanolamine metabolic process
IM703_RS03680	COG3264	Mechanosensitive ion channel
IM703_RS03680	COG1511	domain protein
IM703_RS03685	COG0583	DNA-binding transcription factor activity
IM703_RS03690	COG3539	Fimbrial protein
IM703_RS03695	COG3121	Chaperone
IM703_RS03700	COG3188	usher protein
IM703_RS03710	COG0561	phosphatase activity
IM703_RS03715	COG2267	carboxylic ester hydrolase activity
IM703_RS03720	COG0514	ATP-dependent DNA helicase (RecQ)
IM703_RS03730	COG2050	protein possibly involved in aromatic compounds catabolism
IM703_RS03735	COG2962	Rard protein
IM703_RS03745	COG0210	DNA helicase
IM703_RS03750	COG1011	Hydrolase
IM703_RS03765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM703_RS03775	COG1965	Belongs to the frataxin family
IM703_RS03785	COG0181	hydroxymethylbilane synthase activity
IM703_RS03795	COG2959	enzyme of heme biosynthesis
IM703_RS03800	COG3071	HemY protein
IM703_RS03830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IM703_RS03840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM703_RS03845	COG2244	polysaccharide biosynthetic process
IM703_RS03850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM703_RS03855	COG0456	acetyltransferase
IM703_RS03860	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IM703_RS03865	COG1088	dTDP-glucose 4,6-dehydratase activity
IM703_RS03870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IM703_RS03875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IM703_RS03885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM703_RS03890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IM703_RS03895	COG3118	belongs to the thioredoxin family
IM703_RS03900	COG0513	Belongs to the DEAD box helicase family
IM703_RS03905	COG0248	Ppx GppA phosphatase
IM703_RS03915	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM703_RS03930	COG0129	dihydroxy-acid dehydratase activity
IM703_RS03940	COG3978	acetolactate synthase activity
IM703_RS03955	COG0606	chelatase, subunit chli
IM703_RS03960	COG3085	chromosome segregation
IM703_RS03965	COG0583	DNA-binding transcription factor activity
IM703_RS04000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IM703_RS04010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM703_RS04015	COG0009	L-threonylcarbamoyladenylate synthase
IM703_RS04020	COG0551	DNA topoisomerase type I activity
IM703_RS04025	COG0758	DNA mediated transformation
IM703_RS04030	COG0242	peptide deformylase activity
IM703_RS04035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM703_RS04040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM703_RS04040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM703_RS04045	COG0569	domain protein
IM703_RS04050	COG1970	mechanosensitive ion channel activity
IM703_RS04055	COG3036	rescue of stalled ribosome
IM703_RS04060	COG0789	Transcriptional regulator
IM703_RS04065	COG0203	ribosomal protein L17
IM703_RS04075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IM703_RS04085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IM703_RS04090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM703_RS04095	COG0201	protein transport
IM703_RS04100	COG0200	Binds to the 23S rRNA
IM703_RS04105	COG1841	ribosomal large subunit assembly
IM703_RS04110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IM703_RS04115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IM703_RS04120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IM703_RS04125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IM703_RS04130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM703_RS04135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IM703_RS04140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IM703_RS04145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IM703_RS04150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IM703_RS04155	COG0255	Belongs to the universal ribosomal protein uL29 family
IM703_RS04160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM703_RS04170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IM703_RS04175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IM703_RS04180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IM703_RS04185	COG0089	rRNA binding
IM703_RS04190	COG0088	Forms part of the polypeptide exit tunnel
IM703_RS04195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IM703_RS04200	COG0051	transcription antitermination factor activity, RNA binding
IM703_RS04240	COG1072	(Pantothenic acid kinase))
IM703_RS04250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM703_RS04285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM703_RS04290	COG4206	TonB-dependent receptor
IM703_RS04295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM703_RS04310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM703_RS04320	COG0165	Argininosuccinate lyase
IM703_RS04325	COG0137	argininosuccinate synthase activity
IM703_RS04330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM703_RS04335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM703_RS04340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM703_RS04345	COG0028	Belongs to the TPP enzyme family
IM703_RS04365	COG0583	DNA-binding transcription factor activity
IM703_RS04370	COG0477	Major facilitator Superfamily
IM703_RS04380	COG1216	Glycosyl transferase, family 2
IM703_RS04385	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IM703_RS04390	COG0460	homoserine dehydrogenase
IM703_RS04390	COG0527	aspartate kinase activity
IM703_RS04395	COG0626	cystathionine gamma-synthase activity
IM703_RS04400	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IM703_RS04405	COG3550	peptidyl-serine autophosphorylation
IM703_RS04410	COG0254	rRNA binding
IM703_RS04415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IM703_RS04420	COG1609	Transcriptional regulator
IM703_RS04425	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM703_RS04430	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IM703_RS04435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IM703_RS04440	COG1575	Belongs to the MenA family. Type 1 subfamily
IM703_RS04445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM703_RS04450	COG3074	FtsZ-dependent cytokinesis
IM703_RS04460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM703_RS04465	COG2814	Major facilitator Superfamily
IM703_RS04470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM703_RS04475	COG3152	Membrane
IM703_RS04485	COG0149	triose-phosphate isomerase activity
IM703_RS04490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IM703_RS04495	COG0205	6-phosphofructokinase activity
IM703_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
IM703_RS04505	COG3678	ATP-independent chaperone mediated protein folding
IM703_RS04510	COG0745	RESPONSE REGULATOR receiver
IM703_RS04515	COG2205	protein histidine kinase activity
IM703_RS04570	COG1216	Glycosyl transferase, family 2
IM703_RS04570	COG1442	glycosyl transferase family 8
IM703_RS04580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IM703_RS04585	COG1045	serine acetyltransferase
IM703_RS04590	COG1045	serine acetyltransferase
IM703_RS04600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IM703_RS04605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM703_RS04610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM703_RS04615	COG4942	peptidase
IM703_RS04620	COG2861	carbohydrate metabolic process
IM703_RS04625	COG1063	alcohol dehydrogenase
IM703_RS04630	COG0156	8-amino-7-oxononanoate synthase activity
IM703_RS04635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM703_RS04645	COG0859	PFAM glycosyl transferase family 9
IM703_RS04650	COG1216	Glycosyl transferase, family 2
IM703_RS04650	COG1442	glycosyl transferase family 8
IM703_RS04655	COG0859	PFAM glycosyl transferase family 9
IM703_RS04665	COG0438	transferase activity, transferring glycosyl groups
IM703_RS04675	COG0859	PFAM glycosyl transferase family 9
IM703_RS04680	COG1519	Transferase
IM703_RS04690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM703_RS04695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM703_RS04710	COG0297	glycogen (starch) synthase activity
IM703_RS04720	COG0438	transferase activity, transferring glycosyl groups
IM703_RS04725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM703_RS04730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM703_RS04735	COG2003	Belongs to the UPF0758 family
IM703_RS04740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IM703_RS04745	COG0756	dUTP diphosphatase activity
IM703_RS04750	COG1309	transcriptional regulator
IM703_RS04755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM703_RS04760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM703_RS04765	COG1561	YicC-like family, N-terminal region
IM703_RS04770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM703_RS04795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM703_RS04800	COG0187	DNA topoisomerase II activity
IM703_RS04805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM703_RS04815	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM703_RS04820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IM703_RS04825	COG0594	ribonuclease P activity
IM703_RS04830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM703_RS04835	COG0706	membrane insertase activity
IM703_RS04840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IM703_RS04880	COG0583	DNA-binding transcription factor activity
IM703_RS04895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM703_RS04905	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS04910	COG2864	formate dehydrogenase
IM703_RS04915	COG3058	Necessary for formate dehydrogenase activity
IM703_RS04920	COG1921	L-seryl-tRNASec selenium transferase activity
IM703_RS04925	COG3276	selenocysteine insertion sequence binding
IM703_RS04930	COG1368	sulfuric ester hydrolase activity
IM703_RS04940	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IM703_RS04960	COG0457	Tetratricopeptide repeat
IM703_RS04985	COG1940	carbohydrate kinase activity
IM703_RS04995	COG1584	GPR1 FUN34 yaaH family protein
IM703_RS05000	COG3111	PFAM Bacterial OB fold (BOF) protein
IM703_RS05095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM703_RS05100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM703_RS05105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM703_RS05110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM703_RS05115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM703_RS05120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IM703_RS05125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM703_RS05130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM703_RS05140	COG0356	it plays a direct role in the translocation of protons across the membrane
IM703_RS05145	COG3312	ion transport
IM703_RS05150	COG0357	Ribosomal RNA small subunit methyltransferase G
IM703_RS05155	COG0445	tRNA wobble uridine modification
IM703_RS05160	COG0716	FMN binding
IM703_RS05165	COG1522	sequence-specific DNA binding
IM703_RS05170	COG2502	aspartate--ammonia ligase
IM703_RS05175	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IM703_RS05180	COG0714	Associated with various cellular activities
IM703_RS05185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM703_RS05190	COG0477	Major facilitator Superfamily
IM703_RS05195	COG2186	Transcriptional regulator
IM703_RS05230	COG2194	sulfuric ester hydrolase activity
IM703_RS05235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM703_RS05240	COG3162	membrane
IM703_RS05245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM703_RS05250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IM703_RS05255	COG2258	MOSC domain
IM703_RS05260	COG0180	Tryptophanyl-tRNA synthetase
IM703_RS05265	COG0546	phosphoglycolate phosphatase activity
IM703_RS05270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM703_RS05285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM703_RS05290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM703_RS05315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IM703_RS05320	COG0494	nUDIX hydrolase
IM703_RS05330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IM703_RS05335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IM703_RS05340	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IM703_RS05345	COG1741	Belongs to the pirin family
IM703_RS05350	COG2081	HI0933 family
IM703_RS05355	COG0306	phosphate transporter
IM703_RS05365	COG0589	response to stress
IM703_RS05375	COG0742	ribosomal rna small subunit methyltransferase
IM703_RS05405	COG1403	HNH endonuclease
IM703_RS05410	COG3122	Protein conserved in bacteria
IM703_RS05415	COG1278	Cold shock
IM703_RS05430	COG1737	Transcriptional regulator
IM703_RS05435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM703_RS05435	COG1263	PTS System
IM703_RS05440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM703_RS05445	COG0733	neurotransmitter:sodium symporter activity
IM703_RS05450	COG3383	formate dehydrogenase (NAD+) activity
IM703_RS05455	COG2864	formate dehydrogenase
IM703_RS05460	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS05465	COG0243	molybdopterin cofactor binding
IM703_RS05465	COG3383	formate dehydrogenase (NAD+) activity
IM703_RS05475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IM703_RS05475	COG2755	lipolytic protein G-D-S-L family
IM703_RS05480	COG1285	pathogenesis
IM703_RS05485	COG2211	Major facilitator Superfamily
IM703_RS05520	COG3381	protein complex oligomerization
IM703_RS05525	COG3302	dmso reductase anchor subunit
IM703_RS05530	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS05535	COG0243	molybdopterin cofactor binding
IM703_RS05555	COG4604	ABC transporter, ATP-binding protein
IM703_RS05560	COG4605	iron ion homeostasis
IM703_RS05565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM703_RS05570	COG4607	ABC-type enterochelin transport system periplasmic component
IM703_RS05575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM703_RS05580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM703_RS05585	COG1447	Phosphotransferase system cellobiose-specific component IIA
IM703_RS05590	COG2169	Transcriptional regulator
IM703_RS05590	COG1917	Cupin 2, conserved barrel domain protein
IM703_RS05595	COG1486	melibiose metabolic process
IM703_RS05600	COG3394	polysaccharide catabolic process
IM703_RS05625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM703_RS05670	COG1073	alpha beta
IM703_RS05670	COG2226	methyltransferase
IM703_RS05675	COG0747	negative chemotaxis
IM703_RS05680	COG0601	transmembrane transport
IM703_RS05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM703_RS05695	COG1124	(ABC) transporter
IM703_RS05715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM703_RS05755	COG3189	MarR family transcriptional regulator
IM703_RS05760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM703_RS05765	COG1349	DNA-binding transcription factor activity
IM703_RS05770	COG0705	Rhomboid family
IM703_RS05775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM703_RS05780	COG0316	Belongs to the HesB IscA family
IM703_RS05780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM703_RS05790	COG2267	carboxylic ester hydrolase activity
IM703_RS05805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IM703_RS05810	COG1918	ferrous iron import across plasma membrane
IM703_RS05830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM703_RS05840	COG2252	PERMEase
IM703_RS05845	COG4115	mRNA cleavage
IM703_RS05850	COG2161	toxin-antitoxin pair type II binding
IM703_RS05865	COG0765	amino acid transport
IM703_RS05870	COG0765	amino acid transport
IM703_RS05875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM703_RS05880	COG0704	Plays a role in the regulation of phosphate uptake
IM703_RS05890	COG0581	inorganic phosphate transmembrane transporter activity
IM703_RS05895	COG0573	inorganic phosphate transmembrane transporter activity
IM703_RS05900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM703_RS05915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM703_RS05920	COG2183	response to ionizing radiation
IM703_RS05940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM703_RS05960	COG1217	gtp-binding protein TYPA
IM703_RS05965	COG1011	Hydrolase
IM703_RS05970	COG1490	D-aminoacyl-tRNA deacylase activity
IM703_RS05975	COG0456	acetyltransferase
IM703_RS05990	COG2982	Protein involved in outer membrane biogenesis
IM703_RS06000	COG2233	PERMEase
IM703_RS06005	COG0786	glutamate:sodium symporter activity
IM703_RS06010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IM703_RS06015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM703_RS06020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM703_RS06025	COG1758	RNA polymerase activity
IM703_RS06030	COG0194	GDP metabolic process
IM703_RS06035	COG2860	membrane
IM703_RS06040	COG0823	Involved in the tonB-independent uptake of proteins
IM703_RS06050	COG0751	glycine-tRNA ligase activity
IM703_RS06055	COG0752	glycyl-tRNA synthetase alpha subunit
IM703_RS06060	COG2818	Glycosylase
IM703_RS06065	COG3977	Valine--pyruvate aminotransferase
IM703_RS06070	COG0569	domain protein
IM703_RS06070	COG2985	domain, Protein
IM703_RS06075	COG5645	(Lipo)protein
IM703_RS06090	COG0747	negative chemotaxis
IM703_RS06095	COG0601	transmembrane transport
IM703_RS06100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM703_RS06105	COG0444	Belongs to the ABC transporter superfamily
IM703_RS06110	COG4608	Belongs to the ABC transporter superfamily
IM703_RS06115	COG2200	EAL domain
IM703_RS06115	COG2199	diguanylate cyclase activity
IM703_RS06130	COG1942	4-Oxalocrotonate Tautomerase
IM703_RS06135	COG1295	ribonuclease BN
IM703_RS06145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IM703_RS06150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM703_RS06155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM703_RS06180	COG0366	Alpha amylase catalytic
IM703_RS06185	COG1763	Mo-molybdopterin cofactor biosynthetic process
IM703_RS06190	COG0746	molybdenum cofactor guanylyltransferase activity
IM703_RS06195	COG3084	Protein conserved in bacteria
IM703_RS06200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM703_RS06205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM703_RS06210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM703_RS06210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM703_RS06220	COG0242	peptide deformylase activity
IM703_RS06225	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IM703_RS06230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM703_RS06240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM703_RS06245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM703_RS06250	COG1765	OsmC-like protein
IM703_RS06255	COG3954	Phosphoribulokinase
IM703_RS06260	COG3089	Belongs to the UPF0270 family
IM703_RS06265	COG0429	hydrolase of the alpha beta-hydrolase fold
IM703_RS06280	COG0840	transmembrane signaling receptor activity
IM703_RS06285	COG0840	transmembrane signaling receptor activity
IM703_RS06290	COG0840	transmembrane signaling receptor activity
IM703_RS06295	COG0488	(ABC) transporter
IM703_RS06310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IM703_RS06315	COG1047	Peptidyl-prolyl cis-trans
IM703_RS06320	COG2900	Belongs to the SlyX family
IM703_RS06325	COG0545	Peptidyl-prolyl cis-trans isomerase
IM703_RS06340	COG2964	Protein conserved in bacteria
IM703_RS06345	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IM703_RS06350	COG2923	Belongs to the DsrF TusC family
IM703_RS06360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IM703_RS06365	COG0049	tRNA binding
IM703_RS06370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM703_RS06385	COG0250	Participates in transcription elongation, termination and antitermination
IM703_RS06390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IM703_RS06395	COG0081	regulation of translation
IM703_RS06400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IM703_RS06405	COG0222	ribosome binding
IM703_RS06410	COG0085	RNA polymerase activity
IM703_RS06415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IM703_RS06420	COG0726	polysaccharide deacetylase
IM703_RS06440	COG2022	thiamine diphosphate biosynthetic process
IM703_RS06445	COG2104	thiamine diphosphate biosynthetic process
IM703_RS06450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM703_RS06455	COG0352	thiamine-phosphate diphosphorylase activity
IM703_RS06460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM703_RS06470	COG2816	NAD+ diphosphatase activity
IM703_RS06475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IM703_RS06480	COG1515	deoxyribonuclease V activity
IM703_RS06485	COG3068	Protein conserved in bacteria
IM703_RS06505	COG0138	bifunctional purine biosynthesis protein purh
IM703_RS06535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM703_RS06540	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IM703_RS06550	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IM703_RS06555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IM703_RS06560	COG2224	Isocitrate lyase
IM703_RS06570	COG0800	Aldolase
IM703_RS06575	COG0129	dihydroxy-acid dehydratase activity
IM703_RS06585	COG0646	methionine synthase
IM703_RS06585	COG1410	methionine synthase
IM703_RS06600	COG0527	aspartate kinase activity
IM703_RS06605	COG0166	Belongs to the GPI family
IM703_RS06610	COG3161	chorismate lyase activity
IM703_RS06615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IM703_RS06620	COG2937	Belongs to the GPAT DAPAT family
IM703_RS06625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM703_RS06630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM703_RS06635	COG3077	Addiction module antitoxin, RelB DinJ family
IM703_RS06645	COG0735	belongs to the Fur family
IM703_RS06660	COG0814	amino acid
IM703_RS06670	COG1448	Aminotransferase
IM703_RS06690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM703_RS06695	COG3196	Protein conserved in bacteria
IM703_RS06715	COG1177	transmembrane transport
IM703_RS06725	COG0697	spore germination
IM703_RS06730	COG2873	o-acetylhomoserine
IM703_RS06770	COG1454	alcohol dehydrogenase
IM703_RS06770	COG1012	belongs to the aldehyde dehydrogenase family
IM703_RS06775	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
IM703_RS06785	COG1882	Formate acetyltransferase
IM703_RS06790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM703_RS06800	COG4869	propanediol catabolic process
IM703_RS06825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM703_RS06840	COG0789	Transcriptional regulator
IM703_RS06880	COG2207	Transcriptional regulator
IM703_RS06970	COG4771	TonB-dependent receptor
IM703_RS06975	COG0157	Belongs to the NadC ModD family
IM703_RS06980	COG0500	methyltransferase
IM703_RS06985	COG1120	ATPase activity
IM703_RS06990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM703_RS06995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM703_RS07000	COG1609	Transcriptional regulator
IM703_RS07005	COG3265	gluconokinase activity
IM703_RS07010	COG2610	gluconate transmembrane transporter activity
IM703_RS07015	COG0840	transmembrane signaling receptor activity
IM703_RS07035	COG2992	FlgJ-related protein
IM703_RS07055	COG2137	regulation of response to DNA damage stimulus
IM703_RS07095	COG3397	chitin binding
IM703_RS07115	COG1024	Enoyl-CoA hydratase
IM703_RS07120	COG0318	PFAM AMP-dependent synthetase and ligase
IM703_RS07125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM703_RS07130	COG1960	acyl-CoA dehydrogenase activity
IM703_RS07150	COG0644	oxidoreductase
IM703_RS07155	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IM703_RS07160	COG2271	Major facilitator Superfamily
IM703_RS07165	COG0318	PFAM AMP-dependent synthetase and ligase
IM703_RS07175	COG1924	4 iron, 4 sulfur cluster binding
IM703_RS07190	COG2610	gluconate transmembrane transporter activity
IM703_RS07195	COG1960	acyl-CoA dehydrogenase activity
IM703_RS07200	COG2086	electron transfer activity
IM703_RS07205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IM703_RS07215	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IM703_RS07220	COG4977	sequence-specific DNA binding
IM703_RS07255	COG1309	transcriptional regulator
IM703_RS07260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IM703_RS07265	COG1027	Aspartate ammonia-lyase
IM703_RS07275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IM703_RS07280	COG0459	protein refolding
IM703_RS07285	COG0025	NhaP-type Na H and K H
IM703_RS07295	COG1509	lysine 2,3-aminomutase activity
IM703_RS07300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM703_RS07315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IM703_RS07320	COG0651	ATP synthesis coupled electron transport
IM703_RS07325	COG0650	Formate hydrogenlyase subunit 4
IM703_RS07330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM703_RS07335	COG4237	Hydrogenase 4 membrane
IM703_RS07340	COG0651	ATP synthesis coupled electron transport
IM703_RS07345	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IM703_RS07345	COG3261	NADH dehydrogenase
IM703_RS07350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM703_RS07355	COG3260	NADH ubiquinone oxidoreductase 20
IM703_RS07365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IM703_RS07370	COG1216	Glycosyl transferase, family 2
IM703_RS07375	COG0747	negative chemotaxis
IM703_RS07385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM703_RS07410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM703_RS07415	COG1328	CTP reductase activity
IM703_RS07420	COG3726	membrane protein affecting hemolysin expression
IM703_RS07425	COG0560	Phosphoserine phosphatase
IM703_RS07455	COG2382	esterase
IM703_RS07460	COG1785	Belongs to the alkaline phosphatase family
IM703_RS07490	COG2813	Specifically methylates the guanine in position
IM703_RS07505	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IM703_RS07515	COG4667	esterase of the alpha-beta hydrolase superfamily
IM703_RS07520	COG0084	hydrolase, TatD family'
IM703_RS07525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM703_RS07530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IM703_RS07535	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IM703_RS07540	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IM703_RS07545	COG0813	purine-nucleoside phosphorylase activity
IM703_RS07560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IM703_RS07585	COG0469	pyruvate kinase activity
IM703_RS07590	COG2271	Major facilitator Superfamily
IM703_RS07645	COG1461	Dihydroxyacetone kinase
IM703_RS07650	COG2376	Dihydroxyacetone kinase
IM703_RS07745	COG4245	von Willebrand factor, type A
IM703_RS07760	COG1358	cellular component organization or biogenesis
IM703_RS07815	COG0840	transmembrane signaling receptor activity
IM703_RS07830	COG3121	Chaperone
IM703_RS07835	COG3539	Fimbrial protein
IM703_RS07840	COG1396	sequence-specific DNA binding
IM703_RS07845	COG0840	transmembrane signaling receptor activity
IM703_RS07860	COG0358	DNA primase activity
IM703_RS07865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IM703_RS07870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM703_RS07875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IM703_RS07880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM703_RS07885	COG0617	tRNA 3'-terminal CCA addition
IM703_RS07890	COG4991	sh3 domain protein
IM703_RS07895	COG3025	triphosphatase activity
IM703_RS07900	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IM703_RS07905	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IM703_RS07905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IM703_RS07910	COG2188	Transcriptional regulator
IM703_RS07930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM703_RS07935	COG3384	dioxygenase
IM703_RS07950	COG0754	glutathionylspermidine amidase activity
IM703_RS07955	COG5463	Belongs to the UPF0441 family
IM703_RS07960	COG1538	Outer membrane efflux protein
IM703_RS07965	COG0494	nUDIX hydrolase
IM703_RS07970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM703_RS07975	COG3150	esterase
IM703_RS07980	COG0187	DNA topoisomerase II activity
IM703_RS07985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM703_RS07990	COG0204	Acyl-transferase
IM703_RS07995	COG2132	Multicopper oxidase
IM703_RS08015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IM703_RS08020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IM703_RS08025	COG2967	ApaG domain
IM703_RS08030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM703_RS08035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IM703_RS08040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM703_RS08045	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IM703_RS08050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM703_RS08055	COG0564	pseudouridine synthase activity
IM703_RS08060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM703_RS08065	COG0417	DNA replication proofreading
IM703_RS08070	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IM703_RS08075	COG1178	ABC-type Fe3 transport system permease component
IM703_RS08080	COG4143	(ABC) transporter
IM703_RS08085	COG0494	nUDIX hydrolase
IM703_RS08095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM703_RS08100	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IM703_RS08125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IM703_RS08130	COG1025	Belongs to the peptidase M16 family
IM703_RS08135	COG1074	ATP-dependent DNA helicase activity
IM703_RS08140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM703_RS08145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM703_RS08145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM703_RS08150	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM703_RS08170	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IM703_RS08175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM703_RS08180	COG2166	iron-sulfur cluster assembly
IM703_RS08185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM703_RS08190	COG0583	DNA-binding transcription factor activity
IM703_RS08195	COG2363	Small membrane protein
IM703_RS08200	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IM703_RS08205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM703_RS08210	COG1611	Belongs to the LOG family
IM703_RS08215	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM703_RS08215	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM703_RS08230	COG0564	pseudouridine synthase activity
IM703_RS08245	COG0716	FMN binding
IM703_RS08255	COG2171	N-acyltransferase activity
IM703_RS08260	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IM703_RS08270	COG0052	Belongs to the universal ribosomal protein uS2 family
IM703_RS08275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IM703_RS08280	COG0528	UMP kinase activity
IM703_RS08285	COG0233	cytoplasmic translational termination
IM703_RS08290	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IM703_RS08295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM703_RS08300	COG0575	Belongs to the CDS family
IM703_RS08320	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM703_RS08325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM703_RS08330	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM703_RS08335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM703_RS08340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM703_RS08350	COG0825	malonyl-CoA metabolic process
IM703_RS08360	COG0037	tRNA processing
IM703_RS08365	COG4568	rho-dependent transcription termination
IM703_RS08370	COG3015	lipoprotein NlpE involved in copper resistance
IM703_RS08375	COG0442	prolyl-tRNA aminoacylation
IM703_RS08380	COG1720	tRNA m6t6A37 methyltransferase activity
IM703_RS08390	COG1464	Belongs to the NlpA lipoprotein family
IM703_RS08395	COG2011	ABC-type metal ion transport system permease component
IM703_RS08400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM703_RS08405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IM703_RS08435	COG3021	interspecies interaction between organisms
IM703_RS08460	COG0602	queuosine metabolic process
IM703_RS08465	COG0720	synthase
IM703_RS08470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM703_RS08475	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM703_RS08480	COG0175	sulfate reduction
IM703_RS08485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM703_RS08485	COG1648	precorrin-2 dehydrogenase activity
IM703_RS08490	COG0175	sulfate reduction
IM703_RS08495	COG2895	sulfate adenylyltransferase (ATP) activity
IM703_RS08505	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IM703_RS08510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IM703_RS08515	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IM703_RS08520	COG0585	pseudouridine synthase activity
IM703_RS08525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IM703_RS08530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IM703_RS08535	COG4942	peptidase
IM703_RS08535	COG1388	LysM domain
IM703_RS08555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IM703_RS08565	COG2373	Large extracellular alpha-helical protein
IM703_RS08570	COG4953	penicillin-binding protein 1C
IM703_RS08595	COG2720	vancomycin resistance protein
IM703_RS08600	COG0583	DNA-binding transcription factor activity
IM703_RS08605	COG0471	metal ion transport
IM703_RS08625	COG3188	usher protein
IM703_RS08630	COG3539	Fimbrial protein
IM703_RS08645	COG3539	Fimbrial protein
IM703_RS08655	COG0471	metal ion transport
IM703_RS08670	COG1335	isochorismatase
IM703_RS08680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IM703_RS08685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IM703_RS08695	COG0549	Belongs to the carbamate kinase family
IM703_RS08705	COG0583	DNA-binding transcription factor activity
IM703_RS08715	COG4589	Belongs to the CDS family
IM703_RS08730	COG4566	intracellular signal transduction
IM703_RS08750	COG2962	Rard protein
IM703_RS08755	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IM703_RS08760	COG0326	Molecular chaperone. Has ATPase activity
IM703_RS08765	COG0563	adenylate kinase activity
IM703_RS08770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM703_RS08775	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
IM703_RS08780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM703_RS08785	COG4651	solute:proton antiporter activity
IM703_RS08785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM703_RS08790	COG2223	nitrite transmembrane transporter activity
IM703_RS08795	COG0737	Belongs to the 5'-nucleotidase family
IM703_RS08805	COG3735	TraB family
IM703_RS08815	COG2217	Heavy metal translocating P-type atpase
IM703_RS08820	COG0789	Transcriptional regulator
IM703_RS08825	COG1585	Membrane protein implicated in regulation of membrane protease activity
IM703_RS08830	COG0330	HflC and HflK could
IM703_RS08835	COG3118	belongs to the thioredoxin family
IM703_RS08840	COG0300	oxidoreductase activity
IM703_RS08845	COG2755	lipolytic protein G-D-S-L family
IM703_RS08850	COG4181	ATPase activity
IM703_RS08855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IM703_RS08860	COG1982	Orn Lys Arg decarboxylase major
IM703_RS08865	COG0668	transmembrane transport
IM703_RS08875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IM703_RS08880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IM703_RS08885	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM703_RS08890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM703_RS08895	COG0215	cysteine-tRNA ligase activity
IM703_RS08905	COG1105	Belongs to the carbohydrate kinase PfkB family
IM703_RS08910	COG2501	S4 domain
IM703_RS08915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM703_RS08995	COG3042	response to heat
IM703_RS09040	COG1278	Cold shock
IM703_RS09055	COG3772	lysozyme
IM703_RS09090	COG4626	Terminase
IM703_RS09090	COG1802	Transcriptional regulator
IM703_RS09190	COG0582	viral genome integration into host DNA
IM703_RS09195	COG0582	viral genome integration into host DNA
IM703_RS09215	COG0640	Transcriptional regulator
IM703_RS09230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IM703_RS09255	COG3596	GTP binding
IM703_RS09270	COG2378	regulation of single-species biofilm formation
IM703_RS09390	COG3209	COG3209 Rhs family protein
IM703_RS09400	COG3501	Rhs element vgr protein
IM703_RS09580	COG0800	Aldolase
IM703_RS09585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM703_RS09600	COG3119	arylsulfatase activity
IM703_RS09605	COG0641	radical SAM
IM703_RS09610	COG1349	DNA-binding transcription factor activity
IM703_RS09620	COG2222	sugar isomerase
IM703_RS09625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM703_RS09630	COG3715	PTS system
IM703_RS09635	COG3716	PTS system mannose fructose sorbose family IID component
IM703_RS09640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM703_RS09640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM703_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
IM703_RS09685	COG3119	arylsulfatase activity
IM703_RS09710	COG3038	cytochrome b561
IM703_RS09715	COG2353	YceI-like domain
IM703_RS09725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM703_RS09740	COG1115	amino acid carrier protein
IM703_RS09750	COG1151	hydroxylamine reductase activity
IM703_RS09755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM703_RS09765	COG2239	Acts as a magnesium transporter
IM703_RS09770	COG3091	SprT-like family
IM703_RS09775	COG0640	Transcriptional regulator
IM703_RS09790	COG0457	Tetratricopeptide repeat
IM703_RS09790	COG3118	belongs to the thioredoxin family
IM703_RS09795	COG1215	transferase activity, transferring glycosyl groups
IM703_RS09800	COG1215	transferase activity, transferring glycosyl groups
IM703_RS09815	COG2194	sulfuric ester hydrolase activity
IM703_RS09820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM703_RS09825	COG1166	arginine decarboxylase activity
IM703_RS09830	COG0010	Belongs to the arginase family
IM703_RS09840	COG3066	DNA modification
IM703_RS09845	COG4533	DNA binding
IM703_RS09850	COG0066	3-isopropylmalate dehydratase activity
IM703_RS09855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM703_RS09860	COG0473	3-isopropylmalate dehydrogenase activity
IM703_RS09865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM703_RS09875	COG1022	Amp-dependent synthetase and ligase
IM703_RS09885	COG2001	Belongs to the MraZ family
IM703_RS09890	COG0275	rRNA processing
IM703_RS09900	COG0768	penicillin binding
IM703_RS09905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM703_RS09910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM703_RS09915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM703_RS09920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM703_RS09925	COG0772	Belongs to the SEDS family
IM703_RS09930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM703_RS09935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM703_RS09945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IM703_RS09950	COG0849	cell division
IM703_RS09960	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IM703_RS09975	COG0653	protein targeting
IM703_RS09980	COG0789	Transcriptional regulator
IM703_RS10005	COG3033	Beta-eliminating lyase
IM703_RS10010	COG0814	amino acid
IM703_RS10020	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IM703_RS10025	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IM703_RS10030	COG0237	dephospho-CoA kinase activity
IM703_RS10035	COG1459	type II secretion system
IM703_RS10040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM703_RS10045	COG4969	Belongs to the N-Me-Phe pilin family
IM703_RS10050	COG3023	N-Acetylmuramoyl-L-alanine amidase
IM703_RS10060	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM703_RS10065	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM703_RS10070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM703_RS10080	COG3112	Uncharacterised protein family (UPF0231)
IM703_RS10090	COG1279	arginine transmembrane transporter activity
IM703_RS10100	COG0583	DNA-binding transcription factor activity
IM703_RS10105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IM703_RS10110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM703_RS10120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM703_RS10125	COG2274	protein secretion by the type I secretion system
IM703_RS10130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM703_RS10140	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IM703_RS10145	COG3079	Belongs to the UPF0149 family
IM703_RS10150	COG0006	proline dipeptidase activity
IM703_RS10155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM703_RS10160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM703_RS10165	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IM703_RS10170	COG0509	glycine decarboxylation via glycine cleavage system
IM703_RS10175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM703_RS10175	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM703_RS10185	COG0354	folic acid binding
IM703_RS10190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IM703_RS10200	COG0716	FMN binding
IM703_RS10210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM703_RS10215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IM703_RS10225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IM703_RS10310	COG2841	Protein conserved in bacteria
IM703_RS10315	COG4574	serine-type endopeptidase inhibitor activity
IM703_RS10320	COG0589	response to stress
IM703_RS10325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IM703_RS10335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IM703_RS10345	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IM703_RS10350	COG2017	converts alpha-aldose to the beta-anomer
IM703_RS10355	COG1609	Transcriptional regulator
IM703_RS10365	COG4771	TonB-dependent receptor
IM703_RS10380	COG3738	Protein conserved in bacteria
IM703_RS10385	COG0727	PFAM Uncharacterised protein family (UPF0153)
IM703_RS10400	COG1556	Lactate utilization protein
IM703_RS10405	COG1139	Iron-sulfur cluster binding protein
IM703_RS10410	COG0247	lactate metabolic process
IM703_RS10415	COG1620	l-lactate permease
IM703_RS10420	COG2814	Major facilitator Superfamily
IM703_RS10430	COG0583	DNA-binding transcription factor activity
IM703_RS10435	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM703_RS10495	COG2378	regulation of single-species biofilm formation
IM703_RS10510	COG3596	GTP binding
IM703_RS10525	COG3107	peptidoglycan biosynthetic process
IM703_RS10525	COG1674	ftsk spoiiie
IM703_RS10535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IM703_RS10545	COG3311	Transcriptional regulator
IM703_RS10560	COG1196	nuclear chromosome segregation
IM703_RS10570	COG0582	viral genome integration into host DNA
IM703_RS10580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IM703_RS10585	COG2867	negative regulation of translational initiation
IM703_RS10590	COG2914	Belongs to the UPF0125 (RnfH) family
IM703_RS10600	COG0497	DNA recombination
IM703_RS10605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM703_RS10610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM703_RS10615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM703_RS10620	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IM703_RS10625	COG0513	Belongs to the DEAD box helicase family
IM703_RS10630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM703_RS10635	COG1595	DNA-templated transcription, initiation
IM703_RS10640	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IM703_RS10645	COG3026	antisigma factor binding
IM703_RS10650	COG3086	response to oxidative stress
IM703_RS10655	COG0481	GTPase activity
IM703_RS10665	COG0571	ribonuclease III activity
IM703_RS10670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM703_RS10675	COG1381	Involved in DNA repair and RecF pathway recombination
IM703_RS10680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IM703_RS10685	COG0736	holo-[acyl-carrier-protein] synthase activity
IM703_RS10690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IM703_RS10695	COG1280	lysine exporter protein (LysE YggA)
IM703_RS10705	COG3539	Fimbrial protein
IM703_RS10710	COG3539	Fimbrial protein
IM703_RS10715	COG3121	Chaperone
IM703_RS10720	COG3188	usher protein
IM703_RS10725	COG3539	Fimbrial protein
IM703_RS10730	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IM703_RS10735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM703_RS10735	COG0047	phosphoribosylformylglycinamidine synthase activity
IM703_RS10740	COG2205	protein histidine kinase activity
IM703_RS10745	COG3170	Tfp pilus assembly protein FimV
IM703_RS10750	COG2204	response regulator
IM703_RS10755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM703_RS10755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IM703_RS10760	COG0347	Belongs to the P(II) protein family
IM703_RS10770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM703_RS10770	COG1017	nitric oxide dioxygenase activity
IM703_RS10775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM703_RS10780	COG2814	Major facilitator Superfamily
IM703_RS10785	COG0483	inositol monophosphate 1-phosphatase activity
IM703_RS10790	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IM703_RS10795	COG1959	2 iron, 2 sulfur cluster binding
IM703_RS10800	COG1104	cysteine desulfurase activity
IM703_RS10805	COG0822	iron-sulfur transferase activity
IM703_RS10810	COG0316	Belongs to the HesB IscA family
IM703_RS10815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM703_RS10820	COG0443	Heat shock 70 kDa protein
IM703_RS10825	COG0633	Ferredoxin
IM703_RS10830	COG2975	iron-sulfur cluster assembly
IM703_RS10835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM703_RS10845	COG2373	Large extracellular alpha-helical protein
IM703_RS10850	COG4953	penicillin-binding protein 1C
IM703_RS10855	COG0105	UTP biosynthetic process
IM703_RS10860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM703_RS10875	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM703_RS10880	COG0124	histidyl-tRNA synthetase
IM703_RS10885	COG2976	Protein conserved in bacteria
IM703_RS10890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM703_RS10895	COG1160	GTP binding
IM703_RS10915	COG0408	coproporphyrinogen oxidase activity
IM703_RS10920	COG0456	acetyltransferase
IM703_RS10930	COG2837	iron assimilation
IM703_RS10940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IM703_RS10945	COG4208	sulfate ABC transporter
IM703_RS10950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IM703_RS10955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM703_RS10960	COG2190	(PTS) system
IM703_RS10965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM703_RS10970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM703_RS10975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM703_RS10990	COG3115	cell septum assembly
IM703_RS10995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM703_RS11000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM703_RS11005	COG3530	Putative quorum-sensing-regulated virulence factor
IM703_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
IM703_RS11030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM703_RS11070	COG1396	sequence-specific DNA binding
IM703_RS11105	COG2207	Transcriptional regulator
IM703_RS11120	COG4319	ketosteroid isomerase
IM703_RS11130	COG2067	long-chain fatty acid transport protein
IM703_RS11135	COG3691	Protein conserved in bacteria
IM703_RS11140	COG0183	Belongs to the thiolase family
IM703_RS11145	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM703_RS11145	COG1024	Enoyl-CoA hydratase
IM703_RS11150	COG2062	phosphohistidine phosphatase, SixA
IM703_RS11155	COG2840	Smr protein MutS2
IM703_RS11165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM703_RS11170	COG0730	response to heat
IM703_RS11175	COG3101	peptidyl-lysine hydroxylation
IM703_RS11195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM703_RS11195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IM703_RS11200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM703_RS11205	COG0697	spore germination
IM703_RS11210	COG2207	Transcriptional regulator
IM703_RS11215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM703_RS11220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM703_RS11225	COG0101	tRNA pseudouridine synthase activity
IM703_RS11230	COG0586	Pfam SNARE associated Golgi protein
IM703_RS11235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM703_RS11240	COG0285	dihydrofolate synthase activity
IM703_RS11245	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IM703_RS11250	COG1286	toxin biosynthetic process
IM703_RS11255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IM703_RS11260	COG0163	prenyltransferase activity
IM703_RS11265	COG1090	epimerase
IM703_RS11270	COG0625	glutathione transferase activity
IM703_RS11275	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM703_RS11280	COG1609	Transcriptional regulator
IM703_RS11285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM703_RS11295	COG3037	sugar-specific permease SgaT UlaA
IM703_RS11315	COG0280	phosphate acetyltransferase
IM703_RS11315	COG0857	belongs to the CobB CobQ family
IM703_RS11320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM703_RS11325	COG3092	negative regulation of chromosome organization
IM703_RS11330	COG3013	Belongs to the UPF0304 family
IM703_RS11335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM703_RS11340	COG0490	domain, Protein
IM703_RS11340	COG0471	metal ion transport
IM703_RS11350	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IM703_RS11355	COG0436	Aminotransferase
IM703_RS11360	COG0583	DNA-binding transcription factor activity
IM703_RS11365	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM703_RS11370	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM703_RS11375	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM703_RS11375	COG0649	NAD binding
IM703_RS11385	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IM703_RS11395	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IM703_RS11400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM703_RS11405	COG0839	Belongs to the complex I subunit 6 family
IM703_RS11410	COG0713	ATP synthesis coupled electron transport
IM703_RS11415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM703_RS11420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IM703_RS11425	COG1007	ATP synthesis coupled electron transport
IM703_RS11440	COG1169	isochorismate synthase
IM703_RS11445	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IM703_RS11450	COG0596	Alpha beta hydrolase
IM703_RS11455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IM703_RS11460	COG1441	menaquinone biosynthetic process
IM703_RS11480	COG0814	amino acid
IM703_RS11490	COG0633	Ferredoxin
IM703_RS11495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM703_RS11500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM703_RS11505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM703_RS11515	COG2205	protein histidine kinase activity
IM703_RS11515	COG0784	Response regulator, receiver
IM703_RS11520	COG2197	response regulator
IM703_RS11525	COG2198	Histidine kinase
IM703_RS11525	COG0642	Histidine kinase
IM703_RS11580	COG3708	Transcriptional regulator
IM703_RS11580	COG2207	Transcriptional regulator
IM703_RS11595	COG3302	dmso reductase anchor subunit
IM703_RS11600	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS11605	COG0243	molybdopterin cofactor binding
IM703_RS11610	COG0668	transmembrane transport
IM703_RS11620	COG3247	response to pH
IM703_RS11630	COG1396	sequence-specific DNA binding
IM703_RS11635	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IM703_RS11670	COG1902	pentaerythritol trinitrate reductase activity
IM703_RS11690	COG1607	acyl-coa hydrolase
IM703_RS11705	COG2814	Major facilitator Superfamily
IM703_RS11710	COG1560	Kdo2-lipid A biosynthetic process
IM703_RS11750	COG0418	dihydroorotase activity
IM703_RS11770	COG2207	Transcriptional regulator
IM703_RS11775	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM703_RS11800	COG1285	pathogenesis
IM703_RS11815	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM703_RS11820	COG1360	Flagellar Motor Protein
IM703_RS11825	COG0643	Histidine kinase
IM703_RS11825	COG2198	Histidine kinase
IM703_RS11830	COG0835	chemotaxis
IM703_RS11835	COG0840	transmembrane signaling receptor activity
IM703_RS11840	COG0840	transmembrane signaling receptor activity
IM703_RS11850	COG2201	protein-glutamate methylesterase activity
IM703_RS11855	COG0745	RESPONSE REGULATOR receiver
IM703_RS11865	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IM703_RS11890	COG1815	bacterial-type flagellum-dependent cell motility
IM703_RS11895	COG1558	bacterial-type flagellum-dependent cell motility
IM703_RS11920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IM703_RS11925	COG1706	bacterial-type flagellum-dependent cell motility
IM703_RS11960	COG1987	bacterial-type flagellum assembly
IM703_RS11965	COG1338	Plays a role in the flagellum-specific transport system
IM703_RS11985	COG1580	Controls the rotational direction of flagella during chemotaxis
IM703_RS11995	COG2882	bacterial-type flagellum organization
IM703_RS12000	COG1157	protein secretion by the type III secretion system
IM703_RS12005	COG1317	bacterial-type flagellum organization
IM703_RS12020	COG1677	Flagellar hook-basal body complex protein FliE
IM703_RS12040	COG3136	membrane protein required for alginate biosynthesis
IM703_RS12065	COG2153	protein acetylation
IM703_RS12105	COG1191	sigma factor activity
IM703_RS12115	COG0506	proline dehydrogenase activity
IM703_RS12115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IM703_RS12115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IM703_RS12120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM703_RS12150	COG3188	usher protein
IM703_RS12160	COG3121	Chaperone
IM703_RS12170	COG1113	amino acid transport
IM703_RS12185	COG0589	response to stress
IM703_RS12195	COG2226	methyltransferase
IM703_RS12200	COG1971	Probably functions as a manganese efflux pump
IM703_RS12205	COG1760	l-serine dehydratase
IM703_RS12210	COG0494	nUDIX hydrolase
IM703_RS12220	COG3140	Belongs to the UPF0181 family
IM703_RS12235	COG1115	amino acid carrier protein
IM703_RS12240	COG3023	N-Acetylmuramoyl-L-alanine amidase
IM703_RS12245	COG1114	Component of the transport system for branched-chain amino acids
IM703_RS12250	COG0561	phosphatase activity
IM703_RS12265	COG1113	amino acid transport
IM703_RS12285	COG1830	Aldolase
IM703_RS12290	COG1597	lipid kinase activity
IM703_RS12295	COG0826	peptidase U32
IM703_RS12300	COG0745	RESPONSE REGULATOR receiver
IM703_RS12305	COG2205	protein histidine kinase activity
IM703_RS12310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM703_RS12315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM703_RS12320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM703_RS12325	COG3104	oligopeptide transport
IM703_RS12340	COG2239	Acts as a magnesium transporter
IM703_RS12345	COG0248	Ppx GppA phosphatase
IM703_RS12350	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IM703_RS12355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM703_RS12360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IM703_RS12365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM703_RS12370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IM703_RS12375	COG2233	PERMEase
IM703_RS12380	COG0668	transmembrane transport
IM703_RS12385	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM703_RS12390	COG2211	Major facilitator Superfamily
IM703_RS12395	COG1393	Belongs to the ArsC family
IM703_RS12400	COG4783	chaperone-mediated protein folding
IM703_RS12405	COG0628	permease
IM703_RS12410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IM703_RS12415	COG2716	regulation of RNA biosynthetic process
IM703_RS12420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM703_RS12425	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IM703_RS12435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM703_RS12445	COG2378	regulation of single-species biofilm formation
IM703_RS12450	COG2321	neutral zinc metallopeptidase
IM703_RS12455	COG2707	UPF0756 membrane protein
IM703_RS12460	COG1444	tRNA N-acetyltransferase activity
IM703_RS12470	COG2832	Protein of unknown function (DUF454)
IM703_RS12475	COG1876	peptidase activity
IM703_RS12480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM703_RS12485	COG1393	Belongs to the ArsC family
IM703_RS12495	COG2197	response regulator
IM703_RS12500	COG0280	phosphate acetyltransferase
IM703_RS12500	COG0281	malic enzyme
IM703_RS12515	COG1770	oligopeptidase
IM703_RS12520	COG4206	TonB-dependent receptor
IM703_RS12520	COG1629	transport
IM703_RS12525	COG1570	exodeoxyribonuclease VII activity
IM703_RS12530	COG0516	GMP reductase activity
IM703_RS12530	COG0517	IMP dehydrogenase activity
IM703_RS12535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM703_RS12535	COG0519	Catalyzes the synthesis of GMP from XMP
IM703_RS12540	COG0582	viral genome integration into host DNA
IM703_RS12565	COG1136	(ABC) transporter
IM703_RS12580	COG1309	transcriptional regulator
IM703_RS12650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM703_RS12675	COG3541	Predicted nucleotidyltransferase
IM703_RS12690	COG1324	tolerance protein
IM703_RS12695	COG2390	Transcriptional regulator
IM703_RS12700	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM703_RS12710	COG3842	ATPase activity
IM703_RS12765	COG1735	metal-dependent hydrolase with the TIM-barrel fold
IM703_RS12770	COG1494	fructose-1,6-bisphosphatase
IM703_RS12785	COG2197	response regulator
IM703_RS12790	COG0322	excinuclease ABC activity
IM703_RS12795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM703_RS12825	COG1979	alcohol dehydrogenase
IM703_RS12830	COG2207	Transcriptional regulator
IM703_RS12840	COG2226	methyltransferase
IM703_RS12855	COG2076	Multidrug Resistance protein
IM703_RS12865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM703_RS12870	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM703_RS12875	COG2186	Transcriptional regulator
IM703_RS12880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM703_RS12885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM703_RS12890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IM703_RS12895	COG3713	MltA-interacting MipA family protein
IM703_RS12910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM703_RS12915	COG3139	Protein of unknown function (DUF1315)
IM703_RS12920	COG1335	isochorismatase
IM703_RS12925	COG0252	asparaginase activity
IM703_RS12930	COG0616	signal peptide processing
IM703_RS12935	COG0778	Nitroreductase
IM703_RS12940	COG0709	Synthesizes selenophosphate from selenide and ATP
IM703_RS12945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM703_RS12950	COG0708	Exodeoxyribonuclease III
IM703_RS12955	COG0583	DNA-binding transcription factor activity
IM703_RS12965	COG0788	formyltetrahydrofolate deformylase activity
IM703_RS12970	COG3012	SEC-C Motif Domain Protein
IM703_RS12975	COG0745	RESPONSE REGULATOR receiver
IM703_RS12980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM703_RS12990	COG2916	Histone family protein nucleoid-structuring protein H-NS
IM703_RS12995	COG1435	thymidine kinase activity
IM703_RS13000	COG1454	alcohol dehydrogenase
IM703_RS13000	COG1012	belongs to the aldehyde dehydrogenase family
IM703_RS13005	COG2095	MarC family integral membrane protein
IM703_RS13010	COG4608	Belongs to the ABC transporter superfamily
IM703_RS13015	COG0444	Belongs to the ABC transporter superfamily
IM703_RS13020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM703_RS13025	COG0601	transmembrane transport
IM703_RS13030	COG0747	negative chemotaxis
IM703_RS13035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM703_RS13060	COG0601	transmembrane transport
IM703_RS13065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM703_RS13070	COG0444	Belongs to the ABC transporter superfamily
IM703_RS13105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM703_RS13115	COG1280	lysine exporter protein (LysE YggA)
IM703_RS13120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM703_RS13125	COG1309	transcriptional regulator
IM703_RS13130	COG1012	belongs to the aldehyde dehydrogenase family
IM703_RS13135	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IM703_RS13140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IM703_RS13145	COG0402	S-adenosylhomocysteine deaminase activity
IM703_RS13180	COG0113	porphobilinogen synthase activity
IM703_RS13200	COG0589	response to stress
IM703_RS13210	COG0589	response to stress
IM703_RS13215	COG2966	Psort location CytoplasmicMembrane, score
IM703_RS13220	COG3610	response to peptide
IM703_RS13230	COG2356	endonuclease I
IM703_RS13240	COG1702	phosphate starvation-inducible protein PhoH
IM703_RS13250	COG3121	Chaperone
IM703_RS13255	COG3188	usher protein
IM703_RS13260	COG3539	Fimbrial protein
IM703_RS13265	COG3121	Chaperone
IM703_RS13275	COG3152	Membrane
IM703_RS13285	COG1294	oxidase, subunit
IM703_RS13290	COG1271	oxidase subunit
IM703_RS13295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM703_RS13305	COG1280	lysine exporter protein (LysE YggA)
IM703_RS13320	COG0583	DNA-binding transcription factor activity
IM703_RS13325	COG0579	oxidoreductase
IM703_RS13330	COG2186	Transcriptional regulator
IM703_RS13350	COG1122	ATPase activity
IM703_RS13410	COG0012	GTP binding
IM703_RS13415	COG0193	aminoacyl-tRNA hydrolase activity
IM703_RS13425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM703_RS13430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM703_RS13435	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IM703_RS13440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM703_RS13445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM703_RS13460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IM703_RS13465	COG1242	4 iron, 4 sulfur cluster binding
IM703_RS13475	COG0659	secondary active sulfate transmembrane transporter activity
IM703_RS13485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM703_RS13500	COG3381	protein complex oligomerization
IM703_RS13510	COG0477	Major facilitator Superfamily
IM703_RS13515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM703_RS13525	COG1309	transcriptional regulator
IM703_RS13530	COG0728	peptidoglycan biosynthetic process
IM703_RS13540	COG0018	arginyl-trna synthetase
IM703_RS13545	COG3102	Protein conserved in bacteria
IM703_RS13550	COG3142	Participates in the control of copper homeostasis
IM703_RS13555	COG0488	(ABC) transporter
IM703_RS13565	COG0500	methyltransferase
IM703_RS13570	COG2226	methyltransferase
IM703_RS13575	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IM703_RS13580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM703_RS13585	COG0494	nUDIX hydrolase
IM703_RS13590	COG0217	transcriptional regulatory protein
IM703_RS13595	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IM703_RS13600	COG0632	four-way junction helicase activity
IM703_RS13605	COG2255	four-way junction helicase activity
IM703_RS13610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM703_RS13615	COG1121	(ABC) transporter
IM703_RS13620	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IM703_RS13625	COG0739	heme binding
IM703_RS13630	COG1560	Kdo2-lipid A biosynthetic process
IM703_RS13635	COG0469	pyruvate kinase activity
IM703_RS13640	COG1737	Transcriptional regulator
IM703_RS13645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM703_RS13650	COG2076	Multidrug Resistance protein
IM703_RS13655	COG2076	Multidrug Resistance protein
IM703_RS13665	COG0251	oxidation-reduction process
IM703_RS13670	COG1199	ATP-dependent helicase activity
IM703_RS13680	COG3065	identical protein binding
IM703_RS13685	COG0318	PFAM AMP-dependent synthetase and ligase
IM703_RS13690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IM703_RS13695	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IM703_RS13700	COG2894	cell division
IM703_RS13705	COG0850	regulation of cytokinetic process
IM703_RS13710	COG3100	YcgL domain-containing protein
IM703_RS13715	COG2951	lytic endotransglycosylase activity
IM703_RS13720	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM703_RS13725	COG2983	Belongs to the UPF0260 family
IM703_RS13730	COG0384	phenazine biosynthesis protein PhzF
IM703_RS13740	COG0390	transport system, permease component
IM703_RS13745	COG4619	ABC transporter
IM703_RS13755	COG2207	Transcriptional regulator
IM703_RS13755	COG3708	Transcriptional regulator
IM703_RS13770	COG0840	transmembrane signaling receptor activity
IM703_RS13775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM703_RS13780	COG2911	Protein conserved in bacteria
IM703_RS13790	COG3784	Protein of unknown function (DUF1318)
IM703_RS13805	COG3121	Chaperone
IM703_RS13810	COG3121	Chaperone
IM703_RS13825	COG1643	Atp-dependent helicase
IM703_RS13830	COG0531	amino acid
IM703_RS13840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IM703_RS13845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IM703_RS13850	COG0589	response to stress
IM703_RS13855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM703_RS13860	COG0243	molybdopterin cofactor binding
IM703_RS13865	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
IM703_RS13880	COG3321	synthase
IM703_RS13880	COG0604	alcohol dehydrogenase
IM703_RS13890	COG1695	Transcriptional regulator
IM703_RS13925	COG4974	Belongs to the 'phage' integrase family
IM703_RS13970	COG3848	Pyruvate phosphate dikinase
IM703_RS13970	COG0574	Belongs to the PEP-utilizing enzyme family
IM703_RS14000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM703_RS14005	COG4974	Belongs to the 'phage' integrase family
IM703_RS14015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM703_RS14020	COG1129	ABC transporter
IM703_RS14020	COG0842	Transport permease protein
IM703_RS14025	COG0842	Transport permease protein
IM703_RS14040	COG0745	RESPONSE REGULATOR receiver
IM703_RS14045	COG2205	protein histidine kinase activity
IM703_RS14050	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IM703_RS14055	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IM703_RS14060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IM703_RS14075	COG0590	tRNA wobble adenosine to inosine editing
IM703_RS14080	COG3381	protein complex oligomerization
IM703_RS14085	COG3302	dmso reductase anchor subunit
IM703_RS14090	COG0437	4 iron, 4 sulfur cluster binding
IM703_RS14095	COG0243	molybdopterin cofactor binding
IM703_RS14150	COG2376	Dihydroxyacetone kinase
IM703_RS14160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM703_RS14170	COG0251	oxidation-reduction process
IM703_RS14190	COG0058	SHG alpha-glucan phosphorylase activity
IM703_RS14205	COG1523	belongs to the glycosyl hydrolase 13 family
IM703_RS14210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM703_RS14215	COG0583	DNA-binding transcription factor activity
IM703_RS14235	COG0110	maltose O-acetyltransferase activity
IM703_RS14245	COG2022	thiamine diphosphate biosynthetic process
IM703_RS14245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM703_RS14265	COG2169	Transcriptional regulator
IM703_RS14265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM703_RS14275	COG0488	(ABC) transporter
IM703_RS14285	COG0789	Transcriptional regulator
IM703_RS14290	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM703_RS14295	COG0697	spore germination
IM703_RS14325	COG1464	Belongs to the NlpA lipoprotein family
IM703_RS14350	COG2814	Major facilitator Superfamily
IM703_RS14360	COG0583	DNA-binding transcription factor activity
IM703_RS14365	COG0477	Major facilitator Superfamily
IM703_RS14370	COG1309	transcriptional regulator
IM703_RS14380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM703_RS14385	COG1120	ATPase activity
IM703_RS14390	COG4774	siderophore transport
IM703_RS14405	COG4774	siderophore transport
IM703_RS14425	COG0488	(ABC) transporter
IM703_RS14435	COG3721	Heme iron utilization protein
IM703_RS14450	COG4771	TonB-dependent receptor
IM703_RS14455	COG1846	Transcriptional regulator
IM703_RS14460	COG0697	spore germination
IM703_RS14465	COG1671	Belongs to the UPF0178 family
IM703_RS14495	COG0737	Belongs to the 5'-nucleotidase family
IM703_RS14505	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IM703_RS14530	COG0443	Heat shock 70 kDa protein
IM703_RS14545	COG1070	Carbohydrate kinase
IM703_RS14555	COG1757	Na H antiporter
IM703_RS14560	COG0436	Aminotransferase
IM703_RS14565	COG2207	Transcriptional regulator
IM703_RS14565	COG1609	Transcriptional regulator
IM703_RS14570	COG4628	conserved protein (DUF2132)
IM703_RS14575	COG2814	Major facilitator Superfamily
IM703_RS14595	COG1090	epimerase
IM703_RS14625	COG0640	Transcriptional regulator
IM703_RS14635	COG2850	peptidyl-arginine hydroxylation
IM703_RS14655	COG1275	C4-dicarboxylate transporter malic acid transport protein
IM703_RS14665	COG4221	oxidoreductase activity
IM703_RS14680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM703_RS14685	COG1940	carbohydrate kinase activity
IM703_RS14690	COG0583	DNA-binding transcription factor activity
IM703_RS14695	COG2814	Major facilitator Superfamily
IM703_RS14710	COG0114	fumarate hydratase activity
IM703_RS14715	COG5339	Protein conserved in bacteria
IM703_RS14725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM703_RS14735	COG0385	Bile acid
IM703_RS14740	COG0673	inositol 2-dehydrogenase activity
IM703_RS14750	COG4657	Part of a membrane complex involved in electron transport
IM703_RS14760	COG4656	Part of a membrane complex involved in electron transport
IM703_RS14770	COG4659	FMN binding
IM703_RS14780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IM703_RS14785	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IM703_RS14790	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IM703_RS14800	COG0023	Translation Initiation Factor
IM703_RS14805	COG0284	orotidine-5'-phosphate decarboxylase activity
IM703_RS14810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IM703_RS14815	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IM703_RS14820	COG0671	phosphoesterase, PA-phosphatase related
IM703_RS14825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM703_RS14830	COG1464	Belongs to the NlpA lipoprotein family
IM703_RS14835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM703_RS14845	COG0583	DNA-binding transcription factor activity
IM703_RS14855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM703_RS14865	COG0616	signal peptide processing
IM703_RS14870	COG1028	Short-chain dehydrogenase reductase Sdr
IM703_RS14885	COG1187	pseudouridine synthase activity
IM703_RS14890	COG0009	L-threonylcarbamoyladenylate synthase
IM703_RS14895	COG0613	PHP domain protein
IM703_RS14900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM703_RS14905	COG0512	Glutamine amidotransferase of anthranilate synthase
IM703_RS14910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM703_RS14915	COG0135	phosphoribosylanthranilate isomerase activity
IM703_RS14915	COG0134	indole-3-glycerol-phosphate synthase activity
IM703_RS14920	COG0133	tryptophan synthase activity
IM703_RS14925	COG0159	tryptophan synthase activity
IM703_RS14935	COG3047	cAMP biosynthetic process
IM703_RS14950	COG2917	probably involved in intracellular septation
IM703_RS14970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM703_RS14975	COG3099	Belongs to the UPF0263 family
IM703_RS14980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM703_RS15005	COG0346	lactoylglutathione lyase activity
IM703_RS15025	COG0037	tRNA processing
IM703_RS15030	COG0598	Magnesium transport protein CorA
IM703_RS15045	COG4166	transmembrane transport
IM703_RS15050	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IM703_RS15065	COG3768	UPF0283 membrane protein
IM703_RS15070	COG3106	COG3106 Predicted ATPase
IM703_RS15080	COG1983	PspC domain protein
IM703_RS15090	COG1842	Phage shock protein A
IM703_RS15095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IM703_RS15100	COG4166	transmembrane transport
IM703_RS15105	COG4168	peptide transport system, permease
IM703_RS15110	COG4171	peptide transport system, permease
IM703_RS15115	COG4172	Belongs to the ABC transporter superfamily
IM703_RS15120	COG4172	Belongs to the ABC transporter superfamily
IM703_RS15125	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM703_RS15150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM703_RS15155	COG0259	pyridoxamine-phosphate oxidase activity
IM703_RS15160	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IM703_RS15175	COG3313	Fe-S protein
IM703_RS15180	COG0346	lactoylglutathione lyase activity
IM703_RS15185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM703_RS15190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IM703_RS15200	COG0730	response to heat
IM703_RS15215	COG1609	Transcriptional regulator
IM703_RS15220	COG0583	DNA-binding transcription factor activity
IM703_RS15225	COG2814	Major facilitator Superfamily
IM703_RS15230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM703_RS15235	COG0307	riboflavin synthase, alpha
IM703_RS15240	COG0534	Mate efflux family protein
IM703_RS15275	COG1388	LysM domain
IM703_RS15275	COG1376	ErfK ybiS ycfS ynhG family protein
IM703_RS15280	COG2166	iron-sulfur cluster assembly
IM703_RS15285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM703_RS15290	COG0719	Fe-S assembly protein
IM703_RS15295	COG0396	ATPase activity
IM703_RS15300	COG0719	Fe-S assembly protein
IM703_RS15305	COG0316	Belongs to the HesB IscA family
IM703_RS15315	COG2050	protein possibly involved in aromatic compounds catabolism
IM703_RS15320	COG0247	lactate metabolic process
IM703_RS15320	COG0277	FAD linked oxidase domain protein
IM703_RS15325	COG0628	permease
IM703_RS15330	COG0574	Belongs to the PEP-utilizing enzyme family
IM703_RS15330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM703_RS15335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IM703_RS15350	COG4771	TonB-dependent receptor
IM703_RS15355	COG4771	TonB-dependent receptor
IM703_RS15360	COG3720	iron ion transport
IM703_RS15365	COG4558	Periplasmic binding protein
IM703_RS15370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM703_RS15375	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IM703_RS15380	COG2207	Transcriptional regulator
IM703_RS15385	COG0095	Lipoate-protein ligase
IM703_RS15390	COG0791	NLP P60 protein
IM703_RS15395	COG2076	Multidrug Resistance protein
IM703_RS15400	COG2076	Multidrug Resistance protein
IM703_RS15405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IM703_RS15410	COG0726	polysaccharide deacetylase
IM703_RS15415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM703_RS15415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM703_RS15420	COG0463	Glycosyl transferase, family 2
IM703_RS15425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM703_RS15430	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IM703_RS15435	COG4139	cobalamin transport
IM703_RS15440	COG0776	regulation of translation
IM703_RS15445	COG0072	phenylalanine-tRNA ligase activity
IM703_RS15445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM703_RS15450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM703_RS15455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM703_RS15460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM703_RS15465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IM703_RS15470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM703_RS15655	COG3646	Phage regulatory protein
IM703_RS15900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM703_RS15920	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM703_RS15925	COG1121	(ABC) transporter
IM703_RS15930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM703_RS15935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM703_RS15940	COG3001	Fructosamine kinase
IM703_RS15950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM703_RS15955	COG1988	membrane-bound metal-dependent
IM703_RS15960	COG1823	symporter activity
IM703_RS15970	COG0501	Belongs to the peptidase M48B family
IM703_RS15985	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IM703_RS15990	COG1956	GAF domain-containing protein
IM703_RS15995	COG2995	paraquat-inducible protein a
IM703_RS16000	COG3008	intermembrane lipid transfer
IM703_RS16015	COG1276	copper resistance
IM703_RS16020	COG2372	response to copper ion
IM703_RS16025	COG1528	Iron-storage protein
IM703_RS16045	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM703_RS16055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM703_RS16065	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IM703_RS16120	COG2841	Protein conserved in bacteria
IM703_RS16145	COG0071	Belongs to the small heat shock protein (HSP20) family
IM703_RS16150	COG1278	Cold shock
IM703_RS16160	COG0702	epimerase
IM703_RS16165	COG1733	regulation of RNA biosynthetic process
IM703_RS16175	COG0538	isocitrate dehydrogenase activity
IM703_RS16190	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IM703_RS16195	COG1309	transcriptional regulator
IM703_RS16225	COG1278	Cold shock
IM703_RS16245	COG0538	isocitrate dehydrogenase activity
IM703_RS16250	COG1187	pseudouridine synthase activity
IM703_RS16260	COG0482	sulfurtransferase activity
IM703_RS16265	COG2915	High frequency lysogenization protein hflD homolog
IM703_RS16270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM703_RS16275	COG0745	RESPONSE REGULATOR receiver
IM703_RS16280	COG2205	protein histidine kinase activity
IM703_RS16285	COG2850	peptidyl-arginine hydroxylation
IM703_RS16305	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM703_RS16315	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM703_RS16320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IM703_RS16325	COG3134	Outer membrane lipoprotein
IM703_RS16330	COG1252	NADH dehydrogenase
IM703_RS16340	COG1472	Belongs to the glycosyl hydrolase 3 family
IM703_RS16350	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
IM703_RS16355	COG5633	Lipoprotein
IM703_RS16360	COG0537	adenosine 5'-monophosphoramidase activity
IM703_RS16365	COG0084	hydrolase, TatD family'
IM703_RS16370	COG0470	DNA polymerase III
IM703_RS16375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM703_RS16380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM703_RS16385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM703_RS16390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM703_RS16395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM703_RS16410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM703_RS16415	COG0416	fatty acid biosynthetic process
IM703_RS16420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IM703_RS16425	COG1399	metal-binding, possibly nucleic acid-binding protein
IM703_RS16430	COG0424	maF-like protein
IM703_RS16440	COG0564	pseudouridine synthase activity
IM703_RS16445	COG1530	ribonuclease E activity
IM703_RS16450	COG2926	Belongs to the UPF0265 family
IM703_RS16455	COG2211	Major facilitator Superfamily
IM703_RS16460	COG2925	Exonuclease
IM703_RS16470	COG0277	FAD linked oxidase domain protein
IM703_RS16475	COG0583	DNA-binding transcription factor activity
IM703_RS16480	COG3961	Belongs to the TPP enzyme family
IM703_RS16505	COG3210	domain, Protein
IM703_RS16515	COG3210	domain, Protein
IM703_RS16525	COG3210	domain, Protein
IM703_RS16525	COG3210	domain, Protein
IM703_RS16525	COG3210	domain, Protein
IM703_RS16530	COG2831	hemolysin activation secretion protein
IM703_RS16540	COG3188	usher protein
IM703_RS16550	COG3121	Chaperone
IM703_RS16575	COG0531	amino acid
IM703_RS16580	COG4771	TonB-dependent receptor
IM703_RS16585	COG1120	ATPase activity
IM703_RS16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM703_RS16595	COG0833	amino acid
IM703_RS16600	COG0583	DNA-binding transcription factor activity
IM703_RS16605	COG2855	membrane
IM703_RS16610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IM703_RS16615	COG1105	Belongs to the carbohydrate kinase PfkB family
IM703_RS16620	COG0494	nUDIX hydrolase
IM703_RS16630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM703_RS16645	COG0671	phosphoesterase, PA-phosphatase related
IM703_RS16650	COG0791	NLP P60 protein
IM703_RS16660	COG2814	Major facilitator Superfamily
IM703_RS16665	COG1187	pseudouridine synthase activity
IM703_RS16670	COG1061	Type III restriction enzyme res subunit
IM703_RS16675	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM703_RS16680	COG3081	Nucleoid-associated protein
IM703_RS16685	COG3082	Protein of unknown function (DUF1414)
IM703_RS16690	COG3083	sulfuric ester hydrolase activity
IM703_RS16740	COG1560	Kdo2-lipid A biosynthetic process
IM703_RS16745	COG1278	Cold shock
IM703_RS16760	COG2207	Transcriptional regulator
IM703_RS16760	COG3708	Transcriptional regulator
IM703_RS16780	COG0656	L-ascorbic acid biosynthetic process
IM703_RS16785	COG3615	Tellurite resistance protein tehB
IM703_RS16795	COG0583	DNA-binding transcription factor activity
IM703_RS16810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM703_RS16815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM703_RS16820	COG1957	nucleoside hydrolase
IM703_RS16865	COG2920	part of a sulfur-relay system
IM703_RS16870	COG1254	Belongs to the acylphosphatase family
IM703_RS16875	COG3785	DNA binding
IM703_RS16880	COG1832	CoA-binding protein
IM703_RS16885	COG1803	Methylglyoxal synthase
IM703_RS16890	COG0210	DNA helicase
IM703_RS16895	COG1289	transmembrane transporter activity
IM703_RS16900	COG3070	regulator of competence-specific genes
IM703_RS16910	COG2885	chlorophyll binding
IM703_RS16910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IM703_RS16915	COG3120	sequence-specific DNA binding
IM703_RS16920	COG1067	ATP-dependent peptidase activity
IM703_RS16925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM703_RS16930	COG3130	regulation of translation
IM703_RS16940	COG3009	Protein conserved in bacteria
IM703_RS16945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM703_RS16945	COG3008	intermembrane lipid transfer
IM703_RS16950	COG2995	paraquat-inducible protein a
IM703_RS16955	COG0488	(ABC) transporter
IM703_RS16960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM703_RS16960	COG0116	Belongs to the methyltransferase superfamily
IM703_RS16965	COG3217	Mosc domain protein beta barrel domain protein
IM703_RS16965	COG0633	Ferredoxin
IM703_RS16975	COG0167	dihydroorotate dehydrogenase activity
IM703_RS16980	COG0308	aminopeptidase N
IM703_RS16985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IM703_RS16990	COG0017	Asparaginyl-tRNA synthetase
IM703_RS16995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IM703_RS17000	COG1448	Aminotransferase
IM703_RS17005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM703_RS17010	COG3108	Peptidase M15
IM703_RS17015	COG2989	Protein conserved in bacteria
IM703_RS17020	COG3700	Belongs to the class B bacterial acid phosphatase family
IM703_RS17025	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IM703_RS17030	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IM703_RS17035	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
IM703_RS17040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM703_RS17045	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IM703_RS17050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IM703_RS17055	COG2835	tetraacyldisaccharide 4'-kinase activity
IM703_RS17065	COG1663	tetraacyldisaccharide 4'-kinase activity
IM703_RS17070	COG1132	(ABC) transporter
IM703_RS17075	COG2333	competence protein COMEC
IM703_RS17075	COG0658	competence protein
IM703_RS17080	COG0776	regulation of translation
IM703_RS17085	COG0539	negative regulation of cytoplasmic translation
IM703_RS17090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM703_RS17095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM703_RS17100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM703_RS17110	COG0252	asparaginase activity
IM703_RS17115	COG1944	ATP diphosphatase activity
IM703_RS17120	COG2116	formate transmembrane transporter activity
IM703_RS17125	COG1882	Formate acetyltransferase
IM703_RS17130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM703_RS17140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IM703_RS17145	COG1464	Belongs to the NlpA lipoprotein family
IM703_RS17150	COG2011	ABC-type metal ion transport system permease component
IM703_RS17155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM703_RS17160	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM703_RS17165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IM703_RS17170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IM703_RS17175	COG3107	peptidoglycan biosynthetic process
IM703_RS17175	COG1674	ftsk spoiiie
IM703_RS17185	COG0492	ferredoxin-NADP+ reductase activity
IM703_RS17195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IM703_RS17200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IM703_RS17205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM703_RS17210	COG0542	response to heat
IM703_RS17215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IM703_RS17220	COG1278	Cold shock
IM703_RS17225	COG0577	efflux transmembrane transporter activity
IM703_RS17225	COG1136	(ABC) transporter
IM703_RS17230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM703_RS17235	COG3593	DNA synthesis involved in DNA repair
IM703_RS17240	COG2431	L-lysine efflux transmembrane transporter activity
IM703_RS17245	COG0702	epimerase
IM703_RS17250	COG1126	abc transporter atp-binding protein
IM703_RS17255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM703_RS17260	COG4215	(ABC) transporter
IM703_RS17265	COG4160	amino acid transport
IM703_RS17275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM703_RS17290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IM703_RS17295	COG0432	Pfam Uncharacterised protein family UPF0047
IM703_RS17300	COG0671	phosphoesterase, PA-phosphatase related
IM703_RS17305	COG0814	amino acid
IM703_RS17310	COG1760	l-serine dehydratase
IM703_RS17315	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IM703_RS17320	COG1686	Belongs to the peptidase S11 family
IM703_RS17325	COG0625	glutathione transferase activity
IM703_RS17330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM703_RS17335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IM703_RS17340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IM703_RS17340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM703_RS17345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IM703_RS17345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM703_RS17350	COG0131	Imidazoleglycerol-phosphate dehydratase
IM703_RS17350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IM703_RS17355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM703_RS17360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM703_RS17365	COG0107	imidazoleglycerol-phosphate synthase activity
IM703_RS17370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM703_RS17370	COG0140	phosphoribosyl-ATP diphosphatase activity
IM703_RS17375	COG1454	alcohol dehydrogenase
IM703_RS17380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM703_RS17385	COG1301	dicarboxylic acid transport
IM703_RS17390	COG1301	dicarboxylic acid transport
IM703_RS17395	COG0778	Nitroreductase
IM703_RS17400	COG1733	regulation of RNA biosynthetic process
IM703_RS17435	COG1253	flavin adenine dinucleotide binding
IM703_RS17445	COG3069	C4-dicarboxylate transmembrane transporter activity
IM703_RS17450	COG2982	Protein involved in outer membrane biogenesis
IM703_RS17455	COG0717	Belongs to the dCTP deaminase family
IM703_RS17460	COG0572	uridine kinase
IM703_RS17465	COG0489	protein tyrosine kinase activity
IM703_RS17470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM703_RS17470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM703_RS17475	COG1380	Effector of murein hydrolase LrgA
IM703_RS17480	COG1346	cytolysis
IM703_RS17485	COG0295	cytidine deaminase activity
IM703_RS17490	COG0281	malic enzyme
IM703_RS17495	COG2949	membrane
IM703_RS17500	COG2311	Membrane
IM703_RS17505	COG0302	gtp cyclohydrolase
IM703_RS17510	COG0477	Major facilitator Superfamily
IM703_RS17520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM703_RS17555	COG0583	DNA-binding transcription factor activity
IM703_RS17560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM703_RS17565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM703_RS17585	COG3069	C4-dicarboxylate transmembrane transporter activity
IM703_RS17595	COG2897	thiosulfate sulfurtransferase activity
IM703_RS17600	COG2261	transglycosylase associated protein
IM703_RS17605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM703_RS17610	COG0513	Belongs to the DEAD box helicase family
IM703_RS17615	COG1309	transcriptional regulator
IM703_RS17625	COG1131	(ABC) transporter
IM703_RS17630	COG0842	Transport permease protein
IM703_RS17635	COG0842	Transport permease protein
IM703_RS17640	COG0670	Belongs to the BI1 family
IM703_RS17645	COG0314	molybdopterin synthase activity
IM703_RS17650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IM703_RS17655	COG0315	cyclic pyranopterin monophosphate synthase activity
IM703_RS17660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM703_RS17675	COG0556	nucleotide-excision repair
IM703_RS17685	COG2226	methyltransferase
IM703_RS17690	COG0156	8-amino-7-oxononanoate synthase activity
IM703_RS17695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM703_RS17700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM703_RS17705	COG2706	6-phosphogluconolactonase activity
IM703_RS17710	COG0561	phosphatase activity
IM703_RS17715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IM703_RS17720	COG4149	molybdate abc transporter
IM703_RS17725	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM703_RS17735	COG2005	Transcriptional regulator
IM703_RS17735	COG3585	molybdate ion transport
IM703_RS17765	COG2831	hemolysin activation secretion protein
IM703_RS17770	COG1119	ATPase activity
IM703_RS17775	COG0588	phosphoglycerate mutase activity
IM703_RS17785	COG3157	Type VI secretion system effector, Hcp
IM703_RS17795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM703_RS17820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IM703_RS17825	COG2885	chlorophyll binding
IM703_RS17830	COG0823	Involved in the tonB-independent uptake of proteins
IM703_RS17835	COG3064	Membrane
IM703_RS17840	COG0848	biopolymer transport protein
IM703_RS17845	COG0811	peptide transport
IM703_RS17850	COG0824	Thioesterase
IM703_RS17860	COG2814	Major facilitator Superfamily
IM703_RS17865	COG0583	DNA-binding transcription factor activity
IM703_RS17870	COG3790	cyd operon protein YbgE
IM703_RS17875	COG4890	Cyd operon protein YbgT
IM703_RS17880	COG1294	oxidase, subunit
IM703_RS17885	COG1271	oxidase subunit
IM703_RS17890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IM703_RS17895	COG0045	succinate-CoA ligase (ADP-forming) activity
IM703_RS17900	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM703_RS17905	COG0567	Dehydrogenase, E1 component
IM703_RS17920	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IM703_RS17930	COG0372	Belongs to the citrate synthase family
IM703_RS17940	COG2814	Major facilitator Superfamily
IM703_RS17945	COG3831	ATPase activity
IM703_RS17955	COG0714	Associated with various cellular activities
IM703_RS17960	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IM703_RS17965	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IM703_RS17975	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IM703_RS17995	COG4807	Protein conserved in bacteria
IM703_RS18000	COG0033	Phosphoglucomutase
IM703_RS18005	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IM703_RS18010	COG0596	Alpha beta hydrolase
IM703_RS18020	COG0716	FMN binding
IM703_RS18025	COG0735	belongs to the Fur family
IM703_RS18040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM703_RS18050	COG0363	glucosamine-6-phosphate deaminase activity
IM703_RS18055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IM703_RS18060	COG1846	Transcriptional regulator
IM703_RS18060	COG1940	carbohydrate kinase activity
IM703_RS18110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM703_RS18115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM703_RS18120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM703_RS18125	COG1702	phosphate starvation-inducible protein PhoH
IM703_RS18130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM703_RS18140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IM703_RS18150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM703_RS18175	COG0765	amino acid transport
IM703_RS18180	COG0765	amino acid transport
IM703_RS18185	COG1126	abc transporter atp-binding protein
IM703_RS18190	COG0495	leucyl-tRNA aminoacylation
IM703_RS18195	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IM703_RS18200	COG1466	dna polymerase III delta subunit
IM703_RS18205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IM703_RS18210	COG3272	Protein of unknown function (DUF1722)
IM703_RS18215	COG0799	negative regulation of ribosome biogenesis
IM703_RS18220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IM703_RS18225	COG0768	penicillin binding
IM703_RS18230	COG0772	Belongs to the SEDS family
IM703_RS18235	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM703_RS18240	COG1686	Belongs to the peptidase S11 family
IM703_RS18250	COG0321	lipoyl(octanoyl) transferase activity
IM703_RS18255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IM703_RS18260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM703_RS18270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM703_RS18280	COG1780	Probably involved in ribonucleotide reductase function
IM703_RS18285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM703_RS18295	COG4175	Glycine betaine
IM703_RS18300	COG4176	ABC-type proline glycine betaine transport system permease component
IM703_RS18305	COG2113	Glycine betaine
IM703_RS18315	COG1629	transport
IM703_RS18320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM703_RS18325	COG2267	carboxylic ester hydrolase activity
IM703_RS18330	COG2453	phosphatase
IM703_RS18330	COG0671	phosphoesterase, PA-phosphatase related
IM703_RS18340	COG2814	Major facilitator Superfamily
IM703_RS18345	COG1846	Transcriptional regulator
IM703_RS18350	COG1566	PFAM secretion protein HlyD family protein
IM703_RS18355	COG2814	Major facilitator Superfamily
IM703_RS18360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM703_RS18365	COG3148	PFAM DTW domain containing protein
IM703_RS18370	COG1042	CoA-binding domain protein
IM703_RS18370	COG0045	succinate-CoA ligase (ADP-forming) activity
IM703_RS18370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM703_RS18375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM703_RS18380	COG5544	Lipoprotein
IM703_RS18440	COG2801	Transposase and inactivated derivatives
IM703_RS18445	COG3173	Aminoglycoside phosphotransferase
IM703_RS18450	COG0488	(ABC) transporter
IM703_RS18500	COG0659	secondary active sulfate transmembrane transporter activity
IM703_RS18510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM703_RS18520	COG0629	single-stranded DNA binding
IM703_RS18545	COG1192	Involved in chromosome partitioning
IM703_RS18550	COG2336	PFAM SpoVT AbrB
IM703_RS18555	COG2337	Toxic component of a toxin-antitoxin (TA) module
IM703_RS18590	COG3039	Transposase
IM703_RS18645	COG1737	Transcriptional regulator
IM703_RS18655	COG3069	C4-dicarboxylate transmembrane transporter activity
IM703_RS18660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM703_RS18670	COG3153	acetyltransferase
IM703_RS18800	COG1357	PFAM Pentapeptide repeats (8 copies)
IM703_RS18840	COG0482	sulfurtransferase activity
IM703_RS18855	COG0488	(ABC) transporter
IM703_RS18860	COG3173	Aminoglycoside phosphotransferase
IM703_RS18910	COG1342	Belongs to the UPF0251 family