locus-tag	class	description
JFB93_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFB93_RS00010	COG0592	DNA-directed DNA polymerase activity
JFB93_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JFB93_RS00020	COG0187	DNA topoisomerase II activity
JFB93_RS00025	COG2194	sulfuric ester hydrolase activity
JFB93_RS00030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFB93_RS00035	COG2814	Major facilitator Superfamily
JFB93_RS00045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JFB93_RS00050	COG0254	rRNA binding
JFB93_RS00060	COG1940	carbohydrate kinase activity
JFB93_RS00190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JFB93_RS00195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JFB93_RS00200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JFB93_RS00205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JFB93_RS00210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JFB93_RS00215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JFB93_RS00220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JFB93_RS00225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JFB93_RS00235	COG0356	it plays a direct role in the translocation of protons across the membrane
JFB93_RS00240	COG3312	ion transport
JFB93_RS00245	COG0357	Ribosomal RNA small subunit methyltransferase G
JFB93_RS00250	COG0445	tRNA wobble uridine modification
JFB93_RS00255	COG0716	FMN binding
JFB93_RS00260	COG1522	sequence-specific DNA binding
JFB93_RS00265	COG2502	aspartate--ammonia ligase
JFB93_RS00270	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JFB93_RS00275	COG0714	Associated with various cellular activities
JFB93_RS00280	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS00290	COG1129	ABC transporter
JFB93_RS00295	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFB93_RS00300	COG1879	ABC-type sugar transport system periplasmic component
JFB93_RS00305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFB93_RS00310	COG1609	Transcriptional regulator
JFB93_RS00315	COG0477	Major facilitator Superfamily
JFB93_RS00320	COG2186	Transcriptional regulator
JFB93_RS00355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFB93_RS00360	COG3162	membrane
JFB93_RS00365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JFB93_RS00370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JFB93_RS00375	COG2258	MOSC domain
JFB93_RS00385	COG0583	DNA-binding transcription factor activity
JFB93_RS00395	COG1335	isochorismatase
JFB93_RS00405	COG1304	FMN binding
JFB93_RS00410	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS00415	COG0180	Tryptophanyl-tRNA synthetase
JFB93_RS00420	COG0546	phosphoglycolate phosphatase activity
JFB93_RS00425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JFB93_RS00440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JFB93_RS00445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JFB93_RS00450	COG4796	Type ii and iii secretion system protein
JFB93_RS00470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JFB93_RS00475	COG0494	nUDIX hydrolase
JFB93_RS00485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JFB93_RS00490	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JFB93_RS00495	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JFB93_RS00500	COG1741	Belongs to the pirin family
JFB93_RS00505	COG2197	response regulator
JFB93_RS00565	COG4669	(LipO)protein
JFB93_RS00640	COG5002	protein histidine kinase activity
JFB93_RS00640	COG0784	Response regulator, receiver
JFB93_RS00640	COG2198	Histidine kinase
JFB93_RS00675	COG2081	HI0933 family
JFB93_RS00680	COG0306	phosphate transporter
JFB93_RS00690	COG0589	response to stress
JFB93_RS00700	COG0742	ribosomal rna small subunit methyltransferase
JFB93_RS00715	COG0582	viral genome integration into host DNA
JFB93_RS00760	COG1396	sequence-specific DNA binding
JFB93_RS00770	COG0582	viral genome integration into host DNA
JFB93_RS00790	COG3188	usher protein
JFB93_RS00795	COG3121	Chaperone
JFB93_RS00815	COG3122	Protein conserved in bacteria
JFB93_RS00825	COG1278	Cold shock
JFB93_RS00850	COG3121	Chaperone
JFB93_RS00865	COG1737	Transcriptional regulator
JFB93_RS00870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS00870	COG1263	PTS System
JFB93_RS00875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JFB93_RS00930	COG1388	LysM domain
JFB93_RS00930	COG1470	cell adhesion involved in biofilm formation
JFB93_RS00980	COG2169	Transcriptional regulator
JFB93_RS01025	COG4790	Type iii secretion
JFB93_RS01070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFB93_RS01075	COG0477	Major facilitator Superfamily
JFB93_RS01090	COG0402	S-adenosylhomocysteine deaminase activity
JFB93_RS01095	COG0549	Belongs to the carbamate kinase family
JFB93_RS01105	COG1304	FMN binding
JFB93_RS01110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JFB93_RS01120	COG0666	response to abiotic stimulus
JFB93_RS01125	COG0583	DNA-binding transcription factor activity
JFB93_RS01130	COG2819	hydrolase of the alpha beta superfamily
JFB93_RS01135	COG4771	TonB-dependent receptor
JFB93_RS01140	COG1566	PFAM secretion protein HlyD family protein
JFB93_RS01145	COG2814	Major facilitator Superfamily
JFB93_RS01150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JFB93_RS01155	COG3327	negative regulation of DNA-templated transcription, initiation
JFB93_RS01160	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JFB93_RS01165	COG0183	Belongs to the thiolase family
JFB93_RS01170	COG2050	protein possibly involved in aromatic compounds catabolism
JFB93_RS01175	COG1250	3-hydroxyacyl-CoA dehydrogenase
JFB93_RS01180	COG1024	Enoyl-CoA hydratase
JFB93_RS01185	COG1024	Enoyl-CoA hydratase
JFB93_RS01190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFB93_RS01195	COG2151	metal-sulfur cluster biosynthetic enzyme
JFB93_RS01200	COG3396	Phenylacetate-CoA oxygenase
JFB93_RS01205	COG3460	Phenylacetate-CoA oxygenase
JFB93_RS01210	COG3396	Phenylacetate-CoA oxygenase
JFB93_RS01215	COG2030	dehydratase
JFB93_RS01215	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS01220	COG2226	methyltransferase
JFB93_RS01235	COG0477	Major facilitator Superfamily
JFB93_RS01245	COG0028	Belongs to the TPP enzyme family
JFB93_RS01260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JFB93_RS01270	COG3189	MarR family transcriptional regulator
JFB93_RS01280	COG0488	(ABC) transporter
JFB93_RS01290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JFB93_RS01295	COG1349	DNA-binding transcription factor activity
JFB93_RS01300	COG0705	Rhomboid family
JFB93_RS01305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFB93_RS01310	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JFB93_RS01310	COG0316	Belongs to the HesB IscA family
JFB93_RS01315	COG1040	competence protein
JFB93_RS01320	COG2267	carboxylic ester hydrolase activity
JFB93_RS01335	COG1918	ferrous iron import across plasma membrane
JFB93_RS01340	COG2183	response to ionizing radiation
JFB93_RS01345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JFB93_RS01360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JFB93_RS01365	COG0573	inorganic phosphate transmembrane transporter activity
JFB93_RS01370	COG0581	inorganic phosphate transmembrane transporter activity
JFB93_RS01380	COG0704	Plays a role in the regulation of phosphate uptake
JFB93_RS01385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JFB93_RS01390	COG0765	amino acid transport
JFB93_RS01395	COG0765	amino acid transport
JFB93_RS01400	COG2252	PERMEase
JFB93_RS01405	COG3078	GTPase activator activity
JFB93_RS01410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JFB93_RS01450	COG3539	Fimbrial protein
JFB93_RS01500	COG1695	Transcriptional regulator
JFB93_RS01510	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JFB93_RS01515	COG1473	amidohydrolase
JFB93_RS01520	COG1473	amidohydrolase
JFB93_RS01525	COG0583	DNA-binding transcription factor activity
JFB93_RS01530	COG1011	Hydrolase
JFB93_RS01540	COG0456	acetyltransferase
JFB93_RS01545	COG2982	Protein involved in outer membrane biogenesis
JFB93_RS01550	COG2233	PERMEase
JFB93_RS01555	COG0786	glutamate:sodium symporter activity
JFB93_RS01560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JFB93_RS01565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFB93_RS01570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFB93_RS01575	COG1758	RNA polymerase activity
JFB93_RS01580	COG0194	GDP metabolic process
JFB93_RS01585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JFB93_RS01590	COG2860	membrane
JFB93_RS01595	COG0823	Involved in the tonB-independent uptake of proteins
JFB93_RS01600	COG5645	(Lipo)protein
JFB93_RS01605	COG2985	domain, Protein
JFB93_RS01605	COG0569	domain protein
JFB93_RS01610	COG3977	Valine--pyruvate aminotransferase
JFB93_RS01615	COG2818	Glycosylase
JFB93_RS01625	COG0751	glycine-tRNA ligase activity
JFB93_RS01640	COG0747	negative chemotaxis
JFB93_RS01645	COG0601	transmembrane transport
JFB93_RS01650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFB93_RS01655	COG0444	Belongs to the ABC transporter superfamily
JFB93_RS01660	COG4608	Belongs to the ABC transporter superfamily
JFB93_RS01665	COG2199	diguanylate cyclase activity
JFB93_RS01665	COG2200	EAL domain
JFB93_RS01670	COG0612	Peptidase, M16
JFB93_RS01675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JFB93_RS01685	COG2070	2-Nitropropane dioxygenase
JFB93_RS01690	COG1295	ribonuclease BN
JFB93_RS01700	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JFB93_RS01705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFB93_RS01715	COG2378	regulation of single-species biofilm formation
JFB93_RS01725	COG2723	6-phospho-beta-galactosidase activity
JFB93_RS01740	COG1763	Mo-molybdopterin cofactor biosynthetic process
JFB93_RS01750	COG3084	Protein conserved in bacteria
JFB93_RS01755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JFB93_RS01760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFB93_RS01765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFB93_RS01765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFB93_RS01770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JFB93_RS01775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JFB93_RS01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JFB93_RS01800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JFB93_RS01805	COG1765	OsmC-like protein
JFB93_RS01810	COG3954	Phosphoribulokinase
JFB93_RS01815	COG3089	Belongs to the UPF0270 family
JFB93_RS01820	COG0429	hydrolase of the alpha beta-hydrolase fold
JFB93_RS01830	COG1263	PTS System
JFB93_RS01830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS01835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JFB93_RS01845	COG1982	Orn Lys Arg decarboxylase major
JFB93_RS01850	COG0488	(ABC) transporter
JFB93_RS01855	COG2249	NAD(P)H dehydrogenase (quinone) activity
JFB93_RS01865	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JFB93_RS01870	COG1047	Peptidyl-prolyl cis-trans
JFB93_RS01880	COG0545	Peptidyl-prolyl cis-trans isomerase
JFB93_RS01885	COG2964	Protein conserved in bacteria
JFB93_RS01890	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JFB93_RS01895	COG2923	Belongs to the DsrF TusC family
JFB93_RS01900	COG2168	tRNA wobble position uridine thiolation
JFB93_RS01905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JFB93_RS01910	COG0049	tRNA binding
JFB93_RS01915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JFB93_RS01925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JFB93_RS01930	COG0250	Participates in transcription elongation, termination and antitermination
JFB93_RS01935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JFB93_RS01945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JFB93_RS01950	COG0222	ribosome binding
JFB93_RS01955	COG0085	RNA polymerase activity
JFB93_RS01960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JFB93_RS01970	COG3069	C4-dicarboxylate transmembrane transporter activity
JFB93_RS01975	COG2195	Cleaves the N-terminal amino acid of tripeptides
JFB93_RS01980	COG2233	PERMEase
JFB93_RS01985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JFB93_RS01990	COG2022	thiamine diphosphate biosynthetic process
JFB93_RS01995	COG2104	thiamine diphosphate biosynthetic process
JFB93_RS02000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JFB93_RS02010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JFB93_RS02035	COG3842	ATPase activity
JFB93_RS02055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JFB93_RS02060	COG2816	NAD+ diphosphatase activity
JFB93_RS02065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JFB93_RS02070	COG1515	deoxyribonuclease V activity
JFB93_RS02075	COG3068	Protein conserved in bacteria
JFB93_RS02090	COG0151	Belongs to the GarS family
JFB93_RS02095	COG0138	bifunctional purine biosynthesis protein purh
JFB93_RS02125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JFB93_RS02135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JFB93_RS02140	COG0800	Aldolase
JFB93_RS02145	COG0129	dihydroxy-acid dehydratase activity
JFB93_RS02160	COG3023	N-Acetylmuramoyl-L-alanine amidase
JFB93_RS02185	COG0527	aspartate kinase activity
JFB93_RS02195	COG0166	Belongs to the GPI family
JFB93_RS02200	COG3161	chorismate lyase activity
JFB93_RS02210	COG2937	Belongs to the GPAT DAPAT family
JFB93_RS02215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JFB93_RS02225	COG0735	belongs to the Fur family
JFB93_RS02250	COG3121	Chaperone
JFB93_RS02270	COG1446	asparaginase
JFB93_RS02290	COG0157	Belongs to the NadC ModD family
JFB93_RS02295	COG0500	methyltransferase
JFB93_RS02300	COG1120	ATPase activity
JFB93_RS02305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFB93_RS02315	COG1609	Transcriptional regulator
JFB93_RS02320	COG3265	gluconokinase activity
JFB93_RS02325	COG2610	gluconate transmembrane transporter activity
JFB93_RS02345	COG2992	FlgJ-related protein
JFB93_RS02375	COG2137	regulation of response to DNA damage stimulus
JFB93_RS02380	COG3069	C4-dicarboxylate transmembrane transporter activity
JFB93_RS02385	COG0814	amino acid
JFB93_RS02395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JFB93_RS02405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFB93_RS02410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFB93_RS02420	COG0789	Transcriptional regulator
JFB93_RS02435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JFB93_RS02440	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JFB93_RS02485	COG0179	Fumarylacetoacetate (FAA) hydrolase
JFB93_RS02505	COG0025	NhaP-type Na H and K H
JFB93_RS02530	COG0243	molybdopterin cofactor binding
JFB93_RS02535	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS02545	COG3381	protein complex oligomerization
JFB93_RS02555	COG3541	Predicted nucleotidyltransferase
JFB93_RS02560	COG1690	Belongs to the RtcB family
JFB93_RS02570	COG4650	regulator
JFB93_RS02575	COG1470	cell adhesion involved in biofilm formation
JFB93_RS02575	COG1388	LysM domain
JFB93_RS02580	COG4932	domain protein
JFB93_RS02580	COG2373	Large extracellular alpha-helical protein
JFB93_RS02580	COG1388	LysM domain
JFB93_RS02585	COG1470	cell adhesion involved in biofilm formation
JFB93_RS02585	COG1388	LysM domain
JFB93_RS02595	COG1349	DNA-binding transcription factor activity
JFB93_RS02600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JFB93_RS02610	COG0738	Major facilitator superfamily
JFB93_RS02625	COG0668	transmembrane transport
JFB93_RS02630	COG1982	Orn Lys Arg decarboxylase major
JFB93_RS02635	COG1957	nucleoside hydrolase
JFB93_RS02645	COG0483	inositol monophosphate 1-phosphatase activity
JFB93_RS02650	COG3196	Protein conserved in bacteria
JFB93_RS02660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JFB93_RS02705	COG3121	Chaperone
JFB93_RS02710	COG3121	Chaperone
JFB93_RS02725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JFB93_RS02740	COG2814	Major facilitator Superfamily
JFB93_RS02750	COG0028	Belongs to the TPP enzyme family
JFB93_RS02755	COG0440	acetolactate synthase activity
JFB93_RS02775	COG2814	Major facilitator Superfamily
JFB93_RS02780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JFB93_RS02785	COG2252	PERMEase
JFB93_RS02790	COG0025	NhaP-type Na H and K H
JFB93_RS02800	COG0583	DNA-binding transcription factor activity
JFB93_RS02805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JFB93_RS02810	COG2272	Belongs to the type-B carboxylesterase lipase family
JFB93_RS02820	COG2084	Dehydrogenase
JFB93_RS02825	COG3395	kinase activity
JFB93_RS02830	COG0235	Class ii aldolase
JFB93_RS02835	COG3622	Belongs to the hyi family
JFB93_RS02840	COG1349	DNA-binding transcription factor activity
JFB93_RS02845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFB93_RS02850	COG2610	gluconate transmembrane transporter activity
JFB93_RS02855	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JFB93_RS02865	COG0586	Pfam SNARE associated Golgi protein
JFB93_RS02875	COG2226	methyltransferase
JFB93_RS02880	COG3165	ubiquinone biosynthetic process from chorismate
JFB93_RS02900	COG0805	protein transport
JFB93_RS02915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JFB93_RS02925	COG0183	Belongs to the thiolase family
JFB93_RS02930	COG1024	Enoyl-CoA hydratase
JFB93_RS02930	COG1250	3-hydroxyacyl-CoA dehydrogenase
JFB93_RS02935	COG0006	proline dipeptidase activity
JFB93_RS02940	COG1739	Uncharacterized protein family UPF0029
JFB93_RS02945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JFB93_RS02975	COG2986	histidine ammonia-lyase
JFB93_RS02980	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JFB93_RS02985	COG2197	response regulator
JFB93_RS02990	COG3850	Histidine kinase
JFB93_RS02995	COG2354	Protein conserved in bacteria
JFB93_RS03000	COG1216	Glycosyl transferase, family 2
JFB93_RS03015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JFB93_RS03025	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS03030	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS03040	COG0531	amino acid
JFB93_RS03055	COG1785	Belongs to the alkaline phosphatase family
JFB93_RS03070	COG2813	Specifically methylates the guanine in position
JFB93_RS03080	COG0456	acetyltransferase
JFB93_RS03085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JFB93_RS03095	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS03100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFB93_RS03110	COG0583	DNA-binding transcription factor activity
JFB93_RS03115	COG0473	3-isopropylmalate dehydrogenase activity
JFB93_RS03120	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JFB93_RS03125	COG2823	Periplasmic or secreted lipoprotein
JFB93_RS03130	COG4667	esterase of the alpha-beta hydrolase superfamily
JFB93_RS03135	COG0084	hydrolase, TatD family'
JFB93_RS03140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFB93_RS03150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JFB93_RS03155	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JFB93_RS03160	COG0813	purine-nucleoside phosphorylase activity
JFB93_RS03165	COG1247	-acetyltransferase
JFB93_RS03175	COG0612	Peptidase, M16
JFB93_RS03180	COG4178	(ABC) transporter
JFB93_RS03185	COG4771	TonB-dependent receptor
JFB93_RS03195	COG1595	DNA-templated transcription, initiation
JFB93_RS03205	COG3726	membrane protein affecting hemolysin expression
JFB93_RS03210	COG0560	Phosphoserine phosphatase
JFB93_RS03215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JFB93_RS03225	COG0488	(ABC) transporter
JFB93_RS03230	COG0741	lytic transglycosylase activity
JFB93_RS03235	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JFB93_RS03240	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JFB93_RS03245	COG0406	alpha-ribazole phosphatase activity
JFB93_RS03250	COG2207	Transcriptional regulator
JFB93_RS03250	COG3708	Transcriptional regulator
JFB93_RS03255	COG3045	CreA protein
JFB93_RS03260	COG0745	RESPONSE REGULATOR receiver
JFB93_RS03275	COG0083	homoserine kinase activity
JFB93_RS03290	COG5002	protein histidine kinase activity
JFB93_RS03295	COG0745	RESPONSE REGULATOR receiver
JFB93_RS03325	COG0667	Aldo Keto reductase
JFB93_RS03330	COG3022	response to hydroperoxide
JFB93_RS03335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JFB93_RS03340	COG0521	Mo-molybdopterin cofactor biosynthetic process
JFB93_RS03345	COG1584	GPR1 FUN34 yaaH family protein
JFB93_RS03350	COG0443	Heat shock 70 kDa protein
JFB93_RS03355	COG0484	heat shock protein binding
JFB93_RS03360	COG0402	S-adenosylhomocysteine deaminase activity
JFB93_RS03370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JFB93_RS03375	COG0583	DNA-binding transcription factor activity
JFB93_RS03380	COG0268	Binds directly to 16S ribosomal RNA
JFB93_RS03385	COG0196	riboflavin kinase activity
JFB93_RS03390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JFB93_RS03395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JFB93_RS03400	COG1047	Peptidyl-prolyl cis-trans
JFB93_RS03405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JFB93_RS03415	COG0505	Belongs to the CarA family
JFB93_RS03420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JFB93_RS03425	COG0789	Transcriptional regulator
JFB93_RS03435	COG0626	cystathionine gamma-synthase activity
JFB93_RS03445	COG0848	biopolymer transport protein
JFB93_RS03450	COG2391	methyltransferase activity
JFB93_RS03455	COG0425	Belongs to the sulfur carrier protein TusA family
JFB93_RS03465	COG2974	May be involved in recombination
JFB93_RS03470	COG1940	carbohydrate kinase activity
JFB93_RS03475	COG0737	Belongs to the 5'-nucleotidase family
JFB93_RS03490	COG0419	ATPase involved in DNA repair
JFB93_RS03495	COG0420	3'-5' exonuclease activity
JFB93_RS03500	COG0745	RESPONSE REGULATOR receiver
JFB93_RS03505	COG5002	protein histidine kinase activity
JFB93_RS03525	COG0450	alkyl hydroperoxide reductase
JFB93_RS03530	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
JFB93_RS03535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JFB93_RS03545	COG1862	Preprotein translocase
JFB93_RS03550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFB93_RS03555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFB93_RS03560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JFB93_RS03565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFB93_RS03565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFB93_RS03570	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JFB93_RS03575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JFB93_RS03580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JFB93_RS03585	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JFB93_RS03590	COG2271	Major facilitator Superfamily
JFB93_RS03595	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
JFB93_RS03620	COG1960	acyl-CoA dehydrogenase activity
JFB93_RS03630	COG0318	PFAM AMP-dependent synthetase and ligase
JFB93_RS03655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JFB93_RS03660	COG0142	geranyltranstransferase activity
JFB93_RS03670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFB93_RS03670	COG0301	tRNA thio-modification
JFB93_RS03690	COG0693	protein deglycase activity
JFB93_RS03695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JFB93_RS03700	COG1666	GTP binding
JFB93_RS03705	COG2814	Major facilitator Superfamily
JFB93_RS03710	COG0109	protoheme IX farnesyltransferase activity
JFB93_RS03715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JFB93_RS03720	COG1845	cytochrome c oxidase, subunit III
JFB93_RS03725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JFB93_RS03730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JFB93_RS03740	COG2223	nitrite transmembrane transporter activity
JFB93_RS03745	COG3056	Lipoprotein
JFB93_RS03750	COG0271	Belongs to the BolA IbaG family
JFB93_RS03755	COG0544	peptidyl-prolyl cis-trans isomerase activity
JFB93_RS03760	COG0740	serine-type endopeptidase activity
JFB93_RS03765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JFB93_RS03770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JFB93_RS03775	COG0776	regulation of translation
JFB93_RS03780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JFB93_RS03790	COG0824	Thioesterase
JFB93_RS03800	COG1522	sequence-specific DNA binding
JFB93_RS03805	COG1132	(ABC) transporter
JFB93_RS03810	COG1132	(ABC) transporter
JFB93_RS03820	COG0004	ammonium transporteR
JFB93_RS03825	COG1946	Acyl-CoA thioesterase
JFB93_RS03850	COG0741	lytic transglycosylase activity
JFB93_RS03850	COG1388	LysM domain
JFB93_RS03855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JFB93_RS03860	COG2226	methyltransferase
JFB93_RS03865	COG0328	RNA-DNA hybrid ribonuclease activity
JFB93_RS03905	COG3121	Chaperone
JFB93_RS03910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JFB93_RS03915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JFB93_RS03920	COG0126	phosphoglycerate kinase activity
JFB93_RS03935	COG0786	glutamate:sodium symporter activity
JFB93_RS03940	COG0010	Belongs to the arginase family
JFB93_RS03950	COG0583	DNA-binding transcription factor activity
JFB93_RS03960	COG0590	tRNA wobble adenosine to inosine editing
JFB93_RS03985	COG1704	LemA family
JFB93_RS03990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JFB93_RS03995	COG2368	4-hydroxyphenylacetate
JFB93_RS04015	COG3971	2-oxopent-4-enoate hydratase activity
JFB93_RS04025	COG2814	Major facilitator Superfamily
JFB93_RS04035	COG3384	dioxygenase
JFB93_RS04040	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS04050	COG0179	Fumarylacetoacetate (FAA) hydrolase
JFB93_RS04055	COG1846	Transcriptional regulator
JFB93_RS04060	COG2831	hemolysin activation secretion protein
JFB93_RS04080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JFB93_RS04085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JFB93_RS04105	COG2194	sulfuric ester hydrolase activity
JFB93_RS04110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JFB93_RS04120	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFB93_RS04145	COG1609	Transcriptional regulator
JFB93_RS04150	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFB93_RS04155	COG1129	ABC transporter
JFB93_RS04160	COG1879	ABC-type sugar transport system periplasmic component
JFB93_RS04165	COG1063	alcohol dehydrogenase
JFB93_RS04170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFB93_RS04180	COG0583	DNA-binding transcription factor activity
JFB93_RS04185	COG0004	ammonium transporteR
JFB93_RS04195	COG0601	transmembrane transport
JFB93_RS04200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFB93_RS04210	COG0831	urea catabolic process
JFB93_RS04220	COG0804	urea catabolic process
JFB93_RS04225	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JFB93_RS04235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JFB93_RS04240	COG0829	nickel cation binding
JFB93_RS04245	COG4413	Urea transporter
JFB93_RS04250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JFB93_RS04310	COG0582	viral genome integration into host DNA
JFB93_RS04345	COG0243	molybdopterin cofactor binding
JFB93_RS04355	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS04385	COG0741	lytic transglycosylase activity
JFB93_RS04390	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JFB93_RS04395	COG1194	a g-specific adenine glycosylase
JFB93_RS04405	COG3171	Protein conserved in bacteria
JFB93_RS04410	COG2066	Belongs to the glutaminase family
JFB93_RS04420	COG4607	ABC-type enterochelin transport system periplasmic component
JFB93_RS04425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JFB93_RS04430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JFB93_RS04435	COG0762	integral membrane protein
JFB93_RS04440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JFB93_RS04445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JFB93_RS04450	COG1609	Transcriptional regulator
JFB93_RS04455	COG2211	Major facilitator Superfamily
JFB93_RS04460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JFB93_RS04465	COG0737	Belongs to the 5'-nucleotidase family
JFB93_RS04470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JFB93_RS04475	COG1678	Uncharacterized ACR, COG1678
JFB93_RS04480	COG0189	ligase activity
JFB93_RS04485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JFB93_RS04505	COG0583	DNA-binding transcription factor activity
JFB93_RS04510	COG0583	DNA-binding transcription factor activity
JFB93_RS04520	COG1960	acyl-CoA dehydrogenase activity
JFB93_RS04525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JFB93_RS04530	COG0121	glutamine amidotransferase
JFB93_RS04535	COG3034	peptidoglycan biosynthetic process
JFB93_RS04540	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFB93_RS04545	COG1805	sodium ion transport
JFB93_RS04550	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFB93_RS04555	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFB93_RS04560	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JFB93_RS04565	COG2871	sodium ion transport
JFB93_RS04570	COG1477	protein flavinylation
JFB93_RS04575	COG2991	Protein conserved in bacteria
JFB93_RS04590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JFB93_RS04595	COG2195	Cleaves the N-terminal amino acid of tripeptides
JFB93_RS04600	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JFB93_RS04605	COG1073	alpha beta
JFB93_RS04615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JFB93_RS04620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JFB93_RS04625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JFB93_RS04630	COG0318	PFAM AMP-dependent synthetase and ligase
JFB93_RS04630	COG0204	Acyl-transferase
JFB93_RS04635	COG2814	Major facilitator Superfamily
JFB93_RS04640	COG1546	Belongs to the CinA family
JFB93_RS04645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JFB93_RS04650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JFB93_RS04655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JFB93_RS04680	COG2918	glutathione biosynthetic process
JFB93_RS04685	COG1854	S-ribosylhomocysteine lyase activity
JFB93_RS04690	COG4536	flavin adenine dinucleotide binding
JFB93_RS04695	COG4137	Cytochrome C assembly protein
JFB93_RS04700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JFB93_RS04705	COG0228	four-way junction DNA binding
JFB93_RS04715	COG0336	Belongs to the RNA methyltransferase TrmD family
JFB93_RS04725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JFB93_RS04730	COG0287	Prephenate dehydrogenase
JFB93_RS04730	COG1605	Chorismate mutase
JFB93_RS04735	COG0840	transmembrane signaling receptor activity
JFB93_RS04740	COG1605	Chorismate mutase
JFB93_RS04740	COG0077	Prephenate dehydratase
JFB93_RS04745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JFB93_RS04750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JFB93_RS04755	COG0564	pseudouridine synthase activity
JFB93_RS04760	COG1496	oxidoreductase activity
JFB93_RS04765	COG0542	response to heat
JFB93_RS04800	COG0640	Transcriptional regulator
JFB93_RS04815	COG5544	Lipoprotein
JFB93_RS04820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFB93_RS04830	COG3148	PFAM DTW domain containing protein
JFB93_RS04835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFB93_RS04840	COG2249	NAD(P)H dehydrogenase (quinone) activity
JFB93_RS04845	COG1733	regulation of RNA biosynthetic process
JFB93_RS04855	COG2814	Major facilitator Superfamily
JFB93_RS04860	COG1566	PFAM secretion protein HlyD family protein
JFB93_RS04865	COG1846	Transcriptional regulator
JFB93_RS04870	COG2814	Major facilitator Superfamily
JFB93_RS04875	COG2113	Glycine betaine
JFB93_RS04880	COG4176	ABC-type proline glycine betaine transport system permease component
JFB93_RS04885	COG4175	Glycine betaine
JFB93_RS04900	COG1780	Probably involved in ribonucleotide reductase function
JFB93_RS04905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JFB93_RS04910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JFB93_RS04915	COG1278	Cold shock
JFB93_RS04920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JFB93_RS04930	COG2921	Belongs to the UPF0250 family
JFB93_RS04935	COG1686	Belongs to the peptidase S11 family
JFB93_RS04940	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JFB93_RS04945	COG0772	Belongs to the SEDS family
JFB93_RS04950	COG0768	penicillin binding
JFB93_RS04955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JFB93_RS04960	COG0799	negative regulation of ribosome biogenesis
JFB93_RS04975	COG1466	dna polymerase III delta subunit
JFB93_RS04980	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JFB93_RS04985	COG0495	leucyl-tRNA aminoacylation
JFB93_RS04995	COG1126	abc transporter atp-binding protein
JFB93_RS05000	COG0765	amino acid transport
JFB93_RS05005	COG0765	amino acid transport
JFB93_RS05025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFB93_RS05025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JFB93_RS05030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JFB93_RS05055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JFB93_RS05060	COG4535	Mg2 and Co2 transporter CorC
JFB93_RS05065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JFB93_RS05070	COG1702	phosphate starvation-inducible protein PhoH
JFB93_RS05075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JFB93_RS05080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFB93_RS05085	COG1301	dicarboxylic acid transport
JFB93_RS05125	COG1846	Transcriptional regulator
JFB93_RS05125	COG1940	carbohydrate kinase activity
JFB93_RS05130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JFB93_RS05135	COG0363	glucosamine-6-phosphate deaminase activity
JFB93_RS05140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS05140	COG2190	(PTS) system
JFB93_RS05140	COG1263	PTS System
JFB93_RS05165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JFB93_RS05180	COG1070	Carbohydrate kinase
JFB93_RS05190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFB93_RS05195	COG3775	system Galactitol-specific IIC component
JFB93_RS05205	COG0745	RESPONSE REGULATOR receiver
JFB93_RS05210	COG2205	protein histidine kinase activity
JFB93_RS05215	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JFB93_RS05220	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JFB93_RS05240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JFB93_RS05245	COG2814	Major facilitator Superfamily
JFB93_RS05265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JFB93_RS05270	COG1053	succinate dehydrogenase
JFB93_RS05280	COG0567	Dehydrogenase, E1 component
JFB93_RS05285	COG0508	dehydrogenase complex catalyzes the overall conversion of
JFB93_RS05290	COG0045	succinate-CoA ligase (ADP-forming) activity
JFB93_RS05295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JFB93_RS05300	COG1271	oxidase subunit
JFB93_RS05305	COG1294	oxidase, subunit
JFB93_RS05310	COG4890	Cyd operon protein YbgT
JFB93_RS05320	COG0824	Thioesterase
JFB93_RS05325	COG0811	peptide transport
JFB93_RS05330	COG0848	biopolymer transport protein
JFB93_RS05335	COG3064	Membrane
JFB93_RS05340	COG0823	Involved in the tonB-independent uptake of proteins
JFB93_RS05345	COG2885	chlorophyll binding
JFB93_RS05350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JFB93_RS05385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JFB93_RS05400	COG0588	phosphoglycerate mutase activity
JFB93_RS05410	COG1119	ATPase activity
JFB93_RS05415	COG2005	Transcriptional regulator
JFB93_RS05415	COG3585	molybdate ion transport
JFB93_RS05425	COG5160	protein modification by small protein removal
JFB93_RS05430	COG0725	ABC transporter, periplasmic molybdate-binding protein
JFB93_RS05435	COG4149	molybdate abc transporter
JFB93_RS05440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JFB93_RS05450	COG0561	phosphatase activity
JFB93_RS05455	COG2706	6-phosphogluconolactonase activity
JFB93_RS05465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JFB93_RS05475	COG2226	methyltransferase
JFB93_RS05485	COG0556	nucleotide-excision repair
JFB93_RS05490	COG2066	Belongs to the glutaminase family
JFB93_RS05505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JFB93_RS05510	COG0315	cyclic pyranopterin monophosphate synthase activity
JFB93_RS05515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JFB93_RS05520	COG0314	molybdopterin synthase activity
JFB93_RS05525	COG0670	Belongs to the BI1 family
JFB93_RS05530	COG0842	Transport permease protein
JFB93_RS05535	COG0842	Transport permease protein
JFB93_RS05540	COG1131	(ABC) transporter
JFB93_RS05550	COG1309	transcriptional regulator
JFB93_RS05555	COG0513	Belongs to the DEAD box helicase family
JFB93_RS05560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JFB93_RS05565	COG2261	transglycosylase associated protein
JFB93_RS05570	COG2897	thiosulfate sulfurtransferase activity
JFB93_RS05590	COG5006	permease, DMT superfamily
JFB93_RS05605	COG0488	(ABC) transporter
JFB93_RS05610	COG2824	Alkylphosphonate utilization operon protein PhnA
JFB93_RS05615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JFB93_RS05625	COG0477	Major facilitator Superfamily
JFB93_RS05630	COG0302	gtp cyclohydrolase
JFB93_RS05635	COG2311	Membrane
JFB93_RS05640	COG2949	membrane
JFB93_RS05650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JFB93_RS05655	COG1263	PTS System
JFB93_RS05655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS05675	COG0281	malic enzyme
JFB93_RS05710	COG1346	cytolysis
JFB93_RS05715	COG1380	Effector of murein hydrolase LrgA
JFB93_RS05720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFB93_RS05720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFB93_RS05725	COG0489	protein tyrosine kinase activity
JFB93_RS05735	COG0501	Belongs to the peptidase M48B family
JFB93_RS05740	COG0572	uridine kinase
JFB93_RS05745	COG0717	Belongs to the dCTP deaminase family
JFB93_RS05750	COG2982	Protein involved in outer membrane biogenesis
JFB93_RS05760	COG1253	flavin adenine dinucleotide binding
JFB93_RS05785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JFB93_RS05800	COG0140	phosphoribosyl-ATP diphosphatase activity
JFB93_RS05800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JFB93_RS05805	COG0107	imidazoleglycerol-phosphate synthase activity
JFB93_RS05810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JFB93_RS05815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JFB93_RS05820	COG0131	Imidazoleglycerol-phosphate dehydratase
JFB93_RS05820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JFB93_RS05825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JFB93_RS05825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JFB93_RS05830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JFB93_RS05830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JFB93_RS05840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFB93_RS05845	COG0625	glutathione transferase activity
JFB93_RS05850	COG1686	Belongs to the peptidase S11 family
JFB93_RS05855	COG1760	l-serine dehydratase
JFB93_RS05860	COG0814	amino acid
JFB93_RS05865	COG0671	phosphoesterase, PA-phosphatase related
JFB93_RS05870	COG0432	Pfam Uncharacterised protein family UPF0047
JFB93_RS05890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFB93_RS05895	COG4160	amino acid transport
JFB93_RS05900	COG4215	(ABC) transporter
JFB93_RS05905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JFB93_RS05910	COG1126	abc transporter atp-binding protein
JFB93_RS05915	COG0702	epimerase
JFB93_RS05920	COG2431	L-lysine efflux transmembrane transporter activity
JFB93_RS05925	COG3593	DNA synthesis involved in DNA repair
JFB93_RS05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFB93_RS05935	COG0577	efflux transmembrane transporter activity
JFB93_RS05935	COG1136	(ABC) transporter
JFB93_RS05945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JFB93_RS05945	COG3153	acetyltransferase
JFB93_RS05950	COG1414	Transcriptional regulator
JFB93_RS05960	COG1278	Cold shock
JFB93_RS05965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JFB93_RS05970	COG0542	response to heat
JFB93_RS05975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JFB93_RS05980	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JFB93_RS05985	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JFB93_RS05995	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JFB93_RS06000	COG0492	ferredoxin-NADP+ reductase activity
JFB93_RS06005	COG1522	sequence-specific DNA binding
JFB93_RS06010	COG1674	ftsk spoiiie
JFB93_RS06010	COG3107	peptidoglycan biosynthetic process
JFB93_RS06015	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JFB93_RS06020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JFB93_RS06025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JFB93_RS06040	COG3121	Chaperone
JFB93_RS06055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JFB93_RS06060	COG1882	Formate acetyltransferase
JFB93_RS06065	COG2116	formate transmembrane transporter activity
JFB93_RS06070	COG1414	Transcriptional regulator
JFB93_RS06075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JFB93_RS06080	COG2271	Major facilitator Superfamily
JFB93_RS06085	COG2721	sulfolactate sulfo-lyase activity
JFB93_RS06090	COG1944	ATP diphosphatase activity
JFB93_RS06095	COG0252	asparaginase activity
JFB93_RS06115	COG0735	belongs to the Fur family
JFB93_RS06120	COG0716	FMN binding
JFB93_RS06130	COG1132	(ABC) transporter
JFB93_RS06135	COG0582	viral genome integration into host DNA
JFB93_RS06175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JFB93_RS06255	COG0305	Participates in initiation and elongation during chromosome replication
JFB93_RS06285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JFB93_RS06355	COG1783	phage Terminase large subunit
JFB93_RS06445	COG2274	protein secretion by the type I secretion system
JFB93_RS06450	COG0596	Alpha beta hydrolase
JFB93_RS06455	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JFB93_RS06460	COG0033	Phosphoglucomutase
JFB93_RS06465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JFB93_RS06470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JFB93_RS06475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JFB93_RS06480	COG0539	negative regulation of cytoplasmic translation
JFB93_RS06485	COG0776	regulation of translation
JFB93_RS06490	COG2333	competence protein COMEC
JFB93_RS06490	COG0658	competence protein
JFB93_RS06495	COG1132	(ABC) transporter
JFB93_RS06500	COG1663	tetraacyldisaccharide 4'-kinase activity
JFB93_RS06510	COG2835	tetraacyldisaccharide 4'-kinase activity
JFB93_RS06515	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JFB93_RS06520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JFB93_RS06525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JFB93_RS06530	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
JFB93_RS06535	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JFB93_RS06545	COG5295	Hep Hag repeat protein
JFB93_RS06545	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JFB93_RS06550	COG2989	Protein conserved in bacteria
JFB93_RS06555	COG3108	Peptidase M15
JFB93_RS06560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JFB93_RS06570	COG1448	Aminotransferase
JFB93_RS06575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JFB93_RS06585	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JFB93_RS06590	COG0308	aminopeptidase N
JFB93_RS06595	COG0167	dihydroorotate dehydrogenase activity
JFB93_RS06605	COG0633	Ferredoxin
JFB93_RS06605	COG3217	Mosc domain protein beta barrel domain protein
JFB93_RS06610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JFB93_RS06610	COG0116	Belongs to the methyltransferase superfamily
JFB93_RS06615	COG0488	(ABC) transporter
JFB93_RS06620	COG2995	paraquat-inducible protein a
JFB93_RS06625	COG3008	intermembrane lipid transfer
JFB93_RS06625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JFB93_RS06630	COG3009	Protein conserved in bacteria
JFB93_RS06635	COG3130	regulation of translation
JFB93_RS06640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JFB93_RS06645	COG1067	ATP-dependent peptidase activity
JFB93_RS06655	COG3120	sequence-specific DNA binding
JFB93_RS06670	COG3070	regulator of competence-specific genes
JFB93_RS06675	COG1289	transmembrane transporter activity
JFB93_RS06680	COG0210	DNA helicase
JFB93_RS06685	COG1803	Methylglyoxal synthase
JFB93_RS06690	COG1832	CoA-binding protein
JFB93_RS06695	COG3785	DNA binding
JFB93_RS06700	COG1254	Belongs to the acylphosphatase family
JFB93_RS06705	COG2920	part of a sulfur-relay system
JFB93_RS06840	COG2388	GCN5-related N-acetyl-transferase
JFB93_RS06860	COG3121	Chaperone
JFB93_RS06945	COG3585	molybdate ion transport
JFB93_RS06945	COG2005	Transcriptional regulator
JFB93_RS06955	COG2249	NAD(P)H dehydrogenase (quinone) activity
JFB93_RS06970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JFB93_RS06980	COG1742	UPF0060 membrane protein
JFB93_RS06990	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS06995	COG2864	formate dehydrogenase
JFB93_RS07000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JFB93_RS07035	COG1607	acyl-coa hydrolase
JFB93_RS07060	COG2814	Major facilitator Superfamily
JFB93_RS07065	COG1560	Kdo2-lipid A biosynthetic process
JFB93_RS07095	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JFB93_RS07100	COG3683	transport system, periplasmic component
JFB93_RS07105	COG1054	Belongs to the UPF0176 family
JFB93_RS07120	COG0418	dihydroorotase activity
JFB93_RS07155	COG1285	pathogenesis
JFB93_RS07180	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JFB93_RS07180	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JFB93_RS07180	COG0506	proline dehydrogenase activity
JFB93_RS07190	COG1113	amino acid transport
JFB93_RS07200	COG0582	viral genome integration into host DNA
JFB93_RS07255	COG0835	chemotaxis
JFB93_RS07265	COG0840	transmembrane signaling receptor activity
JFB93_RS07270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JFB93_RS07275	COG2201	protein-glutamate methylesterase activity
JFB93_RS07280	COG0745	RESPONSE REGULATOR receiver
JFB93_RS07310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JFB93_RS07335	COG1815	bacterial-type flagellum-dependent cell motility
JFB93_RS07340	COG1558	bacterial-type flagellum-dependent cell motility
JFB93_RS07365	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JFB93_RS07370	COG1706	bacterial-type flagellum-dependent cell motility
JFB93_RS07380	COG1256	bacterial-type flagellum assembly
JFB93_RS07390	COG1518	maintenance of DNA repeat elements
JFB93_RS07430	COG1338	Plays a role in the flagellum-specific transport system
JFB93_RS07440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JFB93_RS07450	COG1580	Controls the rotational direction of flagella during chemotaxis
JFB93_RS07455	COG3144	bacterial-type flagellum assembly
JFB93_RS07460	COG2882	bacterial-type flagellum organization
JFB93_RS07470	COG1317	bacterial-type flagellum organization
JFB93_RS07480	COG1766	The M ring may be actively involved in energy transduction
JFB93_RS07485	COG1677	Flagellar hook-basal body complex protein FliE
JFB93_RS07495	COG1278	Cold shock
JFB93_RS07500	COG5510	response to toxic substance
JFB93_RS07525	COG0242	peptide deformylase activity
JFB93_RS07550	COG1191	sigma factor activity
JFB93_RS07580	COG0800	Aldolase
JFB93_RS07585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFB93_RS07590	COG1414	Transcriptional regulator
JFB93_RS07605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JFB93_RS07610	COG1309	transcriptional regulator
JFB93_RS07615	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS07620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JFB93_RS07630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JFB93_RS07640	COG0471	metal ion transport
JFB93_RS07660	COG1902	pentaerythritol trinitrate reductase activity
JFB93_RS07665	COG2851	Citrate transporter
JFB93_RS07670	COG2720	vancomycin resistance protein
JFB93_RS07685	COG2828	Protein conserved in bacteria
JFB93_RS07690	COG0471	metal ion transport
JFB93_RS07705	COG3051	citrate lyase alpha subunit
JFB93_RS07710	COG2301	Belongs to the HpcH HpaI aldolase family
JFB93_RS07720	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
JFB93_RS07725	COG3290	protein histidine kinase activity
JFB93_RS07730	COG4565	transcriptional regulatory protein
JFB93_RS07745	COG1494	fructose-1,6-bisphosphatase
JFB93_RS07780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JFB93_RS07785	COG2195	Cleaves the N-terminal amino acid of tripeptides
JFB93_RS07790	COG2197	response regulator
JFB93_RS07795	COG0322	excinuclease ABC activity
JFB93_RS07800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JFB93_RS07845	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JFB93_RS07890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JFB93_RS07895	COG1349	DNA-binding transcription factor activity
JFB93_RS07915	COG1301	dicarboxylic acid transport
JFB93_RS07920	COG0583	DNA-binding transcription factor activity
JFB93_RS07940	COG3037	sugar-specific permease SgaT UlaA
JFB93_RS07950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS07955	COG1609	Transcriptional regulator
JFB93_RS07975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JFB93_RS07990	COG0390	transport system, permease component
JFB93_RS07995	COG4619	ABC transporter
JFB93_RS08000	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS08005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JFB93_RS08010	COG0698	ribose 5-phosphate isomerase
JFB93_RS08015	COG1063	alcohol dehydrogenase
JFB93_RS08020	COG2814	Major facilitator Superfamily
JFB93_RS08025	COG2376	Dihydroxyacetone kinase
JFB93_RS08030	COG1461	Dihydroxyacetone kinase
JFB93_RS08040	COG0477	Major facilitator Superfamily
JFB93_RS08060	COG0246	Mannitol dehydrogenase
JFB93_RS08065	COG1070	Carbohydrate kinase
JFB93_RS08085	COG1473	amidohydrolase
JFB93_RS08110	COG3422	double-strand break repair
JFB93_RS08120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFB93_RS08125	COG0727	PFAM Uncharacterised protein family (UPF0153)
JFB93_RS08180	COG1823	symporter activity
JFB93_RS08185	COG1988	membrane-bound metal-dependent
JFB93_RS08190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFB93_RS08200	COG3001	Fructosamine kinase
JFB93_RS08205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFB93_RS08210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFB93_RS08215	COG1121	(ABC) transporter
JFB93_RS08220	COG0803	Belongs to the bacterial solute-binding protein 9 family
JFB93_RS08255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JFB93_RS08270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JFB93_RS08280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JFB93_RS08285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFB93_RS08285	COG0072	phenylalanine-tRNA ligase activity
JFB93_RS08290	COG0776	regulation of translation
JFB93_RS08300	COG4139	cobalamin transport
JFB93_RS08305	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JFB93_RS08310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JFB93_RS08315	COG0463	Glycosyl transferase, family 2
JFB93_RS08320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JFB93_RS08320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFB93_RS08325	COG0726	polysaccharide deacetylase
JFB93_RS08330	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JFB93_RS08335	COG2076	Multidrug Resistance protein
JFB93_RS08340	COG2076	Multidrug Resistance protein
JFB93_RS08345	COG0791	NLP P60 protein
JFB93_RS08355	COG2207	Transcriptional regulator
JFB93_RS08360	COG3720	iron ion transport
JFB93_RS08375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JFB93_RS08380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JFB93_RS08380	COG0574	Belongs to the PEP-utilizing enzyme family
JFB93_RS08385	COG0628	permease
JFB93_RS08390	COG0247	lactate metabolic process
JFB93_RS08390	COG0277	FAD linked oxidase domain protein
JFB93_RS08395	COG2050	protein possibly involved in aromatic compounds catabolism
JFB93_RS08400	COG0316	Belongs to the HesB IscA family
JFB93_RS08405	COG0719	Fe-S assembly protein
JFB93_RS08410	COG0396	ATPase activity
JFB93_RS08415	COG0719	Fe-S assembly protein
JFB93_RS08420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JFB93_RS08425	COG2166	iron-sulfur cluster assembly
JFB93_RS08430	COG1388	LysM domain
JFB93_RS08430	COG1376	ErfK ybiS ycfS ynhG family protein
JFB93_RS08435	COG4238	major outer membrane lipoprotein
JFB93_RS08440	COG0469	pyruvate kinase activity
JFB93_RS08460	COG0534	Mate efflux family protein
JFB93_RS08465	COG0307	riboflavin synthase, alpha
JFB93_RS08480	COG2814	Major facilitator Superfamily
JFB93_RS08485	COG0583	DNA-binding transcription factor activity
JFB93_RS08490	COG1609	Transcriptional regulator
JFB93_RS08500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JFB93_RS08505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JFB93_RS08510	COG0346	lactoylglutathione lyase activity
JFB93_RS08515	COG3313	Fe-S protein
JFB93_RS08520	COG1846	Transcriptional regulator
JFB93_RS08525	COG3133	Outer membrane lipoprotein
JFB93_RS08530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JFB93_RS08535	COG0259	pyridoxamine-phosphate oxidase activity
JFB93_RS08540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JFB93_RS08545	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JFB93_RS08555	COG3739	integral membrane protein
JFB93_RS08560	COG4172	Belongs to the ABC transporter superfamily
JFB93_RS08570	COG4171	peptide transport system, permease
JFB93_RS08580	COG4166	transmembrane transport
JFB93_RS08590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JFB93_RS08595	COG1842	Phage shock protein A
JFB93_RS08605	COG1983	PspC domain protein
JFB93_RS08610	COG3106	COG3106 Predicted ATPase
JFB93_RS08615	COG3768	UPF0283 membrane protein
JFB93_RS08640	COG4166	transmembrane transport
JFB93_RS08645	COG0598	Magnesium transport protein CorA
JFB93_RS08650	COG0037	tRNA processing
JFB93_RS08675	COG1794	racemase activity, acting on amino acids and derivatives
JFB93_RS08695	COG0791	NLP P60 protein
JFB93_RS08715	COG0589	response to stress
JFB93_RS08725	COG0589	response to stress
JFB93_RS08745	COG2966	Psort location CytoplasmicMembrane, score
JFB93_RS08750	COG3610	response to peptide
JFB93_RS08755	COG2356	endonuclease I
JFB93_RS08760	COG1702	phosphate starvation-inducible protein PhoH
JFB93_RS08765	COG3443	Belongs to the bacterial solute-binding protein 9 family
JFB93_RS08770	COG2375	cellular response to nickel ion
JFB93_RS08780	COG1294	oxidase, subunit
JFB93_RS08785	COG1271	oxidase subunit
JFB93_RS08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JFB93_RS08800	COG1280	lysine exporter protein (LysE YggA)
JFB93_RS08805	COG1522	sequence-specific DNA binding
JFB93_RS08820	COG0243	molybdopterin cofactor binding
JFB93_RS08825	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS08835	COG4772	TonB-dependent receptor
JFB93_RS08850	COG1288	antiporter activity
JFB93_RS08870	COG0583	DNA-binding transcription factor activity
JFB93_RS08880	COG3961	Belongs to the TPP enzyme family
JFB93_RS08885	COG0583	DNA-binding transcription factor activity
JFB93_RS08915	COG3423	Transcriptional regulator
JFB93_RS09025	COG2184	nucleotidyltransferase activity
JFB93_RS09030	COG0582	viral genome integration into host DNA
JFB93_RS09035	COG0012	GTP binding
JFB93_RS09040	COG0193	aminoacyl-tRNA hydrolase activity
JFB93_RS09050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JFB93_RS09055	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JFB93_RS09060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JFB93_RS09065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JFB93_RS09070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JFB93_RS09075	COG2890	protein-(glutamine-N5) methyltransferase activity
JFB93_RS09080	COG2912	Transglutaminase-like superfamily
JFB93_RS09090	COG1242	4 iron, 4 sulfur cluster binding
JFB93_RS09100	COG0659	secondary active sulfate transmembrane transporter activity
JFB93_RS09110	COG2453	phosphatase
JFB93_RS09110	COG0671	phosphoesterase, PA-phosphatase related
JFB93_RS09115	COG2267	carboxylic ester hydrolase activity
JFB93_RS09120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JFB93_RS09135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JFB93_RS09140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JFB93_RS09145	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS09150	COG1115	amino acid carrier protein
JFB93_RS09160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JFB93_RS09165	COG3381	protein complex oligomerization
JFB93_RS09175	COG0477	Major facilitator Superfamily
JFB93_RS09180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JFB93_RS09190	COG0018	arginyl-trna synthetase
JFB93_RS09195	COG3102	Protein conserved in bacteria
JFB93_RS09200	COG3142	Participates in the control of copper homeostasis
JFB93_RS09205	COG0243	molybdopterin cofactor binding
JFB93_RS09210	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS09215	COG3302	dmso reductase anchor subunit
JFB93_RS09220	COG0500	methyltransferase
JFB93_RS09225	COG2226	methyltransferase
JFB93_RS09230	COG3788	relative of glutathione S-transferase, MAPEG superfamily
JFB93_RS09235	COG0494	nUDIX hydrolase
JFB93_RS09245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JFB93_RS09250	COG0494	nUDIX hydrolase
JFB93_RS09255	COG0217	transcriptional regulatory protein
JFB93_RS09260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JFB93_RS09265	COG0632	four-way junction helicase activity
JFB93_RS09270	COG2255	four-way junction helicase activity
JFB93_RS09275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JFB93_RS09280	COG1121	(ABC) transporter
JFB93_RS09285	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JFB93_RS09290	COG0739	heme binding
JFB93_RS09295	COG1560	Kdo2-lipid A biosynthetic process
JFB93_RS09300	COG0469	pyruvate kinase activity
JFB93_RS09305	COG1737	Transcriptional regulator
JFB93_RS09310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JFB93_RS09315	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JFB93_RS09320	COG2076	Multidrug Resistance protein
JFB93_RS09325	COG2076	Multidrug Resistance protein
JFB93_RS09345	COG0251	oxidation-reduction process
JFB93_RS09350	COG1199	ATP-dependent helicase activity
JFB93_RS09360	COG3065	identical protein binding
JFB93_RS09365	COG0318	PFAM AMP-dependent synthetase and ligase
JFB93_RS09390	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JFB93_RS09395	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JFB93_RS09400	COG2894	cell division
JFB93_RS09410	COG3100	YcgL domain-containing protein
JFB93_RS09415	COG2951	lytic endotransglycosylase activity
JFB93_RS09420	COG0179	Fumarylacetoacetate (FAA) hydrolase
JFB93_RS09425	COG2983	Belongs to the UPF0260 family
JFB93_RS09465	COG2999	glutathione oxidoreductase activity
JFB93_RS09475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFB93_RS09480	COG2911	Protein conserved in bacteria
JFB93_RS09490	COG3784	Protein of unknown function (DUF1318)
JFB93_RS09500	COG1643	Atp-dependent helicase
JFB93_RS09505	COG0531	amino acid
JFB93_RS09515	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JFB93_RS09520	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JFB93_RS09530	COG0589	response to stress
JFB93_RS09535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JFB93_RS09540	COG0604	alcohol dehydrogenase
JFB93_RS09540	COG3321	synthase
JFB93_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS09550	COG0814	amino acid
JFB93_RS09575	COG0488	(ABC) transporter
JFB93_RS09585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFB93_RS09590	COG1129	ABC transporter
JFB93_RS09590	COG0842	Transport permease protein
JFB93_RS09595	COG0842	Transport permease protein
JFB93_RS09605	COG3634	alkyl hydroperoxide reductase activity
JFB93_RS09610	COG4974	Belongs to the 'phage' integrase family
JFB93_RS09655	COG0653	protein targeting
JFB93_RS09660	COG4695	Portal protein
JFB93_RS09700	COG3772	lysozyme
JFB93_RS09820	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JFB93_RS09825	COG1403	HNH endonuclease
JFB93_RS09860	COG1126	abc transporter atp-binding protein
JFB93_RS09865	COG0765	amino acid transport
JFB93_RS09880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JFB93_RS09895	COG0825	malonyl-CoA metabolic process
JFB93_RS09900	COG0583	DNA-binding transcription factor activity
JFB93_RS09905	COG5654	RES domain protein
JFB93_RS09910	COG5642	Protein of unknown function (DUF2384)
JFB93_RS09915	COG4807	Protein conserved in bacteria
JFB93_RS09945	COG1051	belongs to the nudix hydrolase family
JFB93_RS09950	COG1280	lysine exporter protein (LysE YggA)
JFB93_RS09960	COG1181	Belongs to the D-alanine--D-alanine ligase family
JFB93_RS09980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JFB93_RS09990	COG2223	nitrite transmembrane transporter activity
JFB93_RS10020	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JFB93_RS10040	COG0583	DNA-binding transcription factor activity
JFB93_RS10045	COG2814	Major facilitator Superfamily
JFB93_RS10050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JFB93_RS10050	COG2169	Transcriptional regulator
JFB93_RS10055	COG2211	Major facilitator Superfamily
JFB93_RS10060	COG2814	Major facilitator Superfamily
JFB93_RS10065	COG2814	Major facilitator Superfamily
JFB93_RS10070	COG1979	alcohol dehydrogenase
JFB93_RS10110	COG0251	oxidation-reduction process
JFB93_RS10125	COG1671	Belongs to the UPF0178 family
JFB93_RS10130	COG1280	lysine exporter protein (LysE YggA)
JFB93_RS10135	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JFB93_RS10165	COG4796	Type ii and iii secretion system protein
JFB93_RS10185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JFB93_RS10190	COG1459	type II secretion system
JFB93_RS10225	COG1132	(ABC) transporter
JFB93_RS10230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFB93_RS10235	COG1136	(ABC) transporter
JFB93_RS10235	COG0577	efflux transmembrane transporter activity
JFB93_RS10245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFB93_RS10255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFB93_RS10260	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS10270	COG4948	Mandelate Racemase Muconate Lactonizing
JFB93_RS10275	COG2271	Major facilitator Superfamily
JFB93_RS10285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JFB93_RS10290	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JFB93_RS10295	COG0583	DNA-binding transcription factor activity
JFB93_RS10320	COG4628	conserved protein (DUF2132)
JFB93_RS10335	COG0625	glutathione transferase activity
JFB93_RS10345	COG3720	iron ion transport
JFB93_RS10375	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JFB93_RS10380	COG1940	carbohydrate kinase activity
JFB93_RS10385	COG0583	DNA-binding transcription factor activity
JFB93_RS10390	COG2814	Major facilitator Superfamily
JFB93_RS10395	COG3397	chitin binding
JFB93_RS10410	COG0114	fumarate hydratase activity
JFB93_RS10415	COG1482	cell wall glycoprotein biosynthetic process
JFB93_RS10420	COG5339	Protein conserved in bacteria
JFB93_RS10425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JFB93_RS10430	COG0385	Bile acid
JFB93_RS10435	COG0673	inositol 2-dehydrogenase activity
JFB93_RS10445	COG4657	Part of a membrane complex involved in electron transport
JFB93_RS10455	COG4656	Part of a membrane complex involved in electron transport
JFB93_RS10465	COG4659	FMN binding
JFB93_RS10475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JFB93_RS10480	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JFB93_RS10490	COG0023	Translation Initiation Factor
JFB93_RS10495	COG0284	orotidine-5'-phosphate decarboxylase activity
JFB93_RS10500	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JFB93_RS10505	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JFB93_RS10510	COG0671	phosphoesterase, PA-phosphatase related
JFB93_RS10515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JFB93_RS10520	COG0113	porphobilinogen synthase activity
JFB93_RS10540	COG0583	DNA-binding transcription factor activity
JFB93_RS10545	COG3590	peptidase
JFB93_RS10550	COG2032	superoxide dismutase activity
JFB93_RS10555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFB93_RS10565	COG0616	signal peptide processing
JFB93_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS10575	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JFB93_RS10580	COG3210	domain, Protein
JFB93_RS10585	COG3700	Belongs to the class B bacterial acid phosphatase family
JFB93_RS10590	COG1187	pseudouridine synthase activity
JFB93_RS10595	COG0009	L-threonylcarbamoyladenylate synthase
JFB93_RS10610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JFB93_RS10610	COG0512	Glutamine amidotransferase of anthranilate synthase
JFB93_RS10615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JFB93_RS10615	COG0512	Glutamine amidotransferase of anthranilate synthase
JFB93_RS10620	COG0134	indole-3-glycerol-phosphate synthase activity
JFB93_RS10620	COG0135	phosphoribosylanthranilate isomerase activity
JFB93_RS10625	COG0133	tryptophan synthase activity
JFB93_RS10630	COG0159	tryptophan synthase activity
JFB93_RS10635	COG3210	domain, Protein
JFB93_RS10640	COG2831	hemolysin activation secretion protein
JFB93_RS10645	COG3047	cAMP biosynthetic process
JFB93_RS10660	COG2917	probably involved in intracellular septation
JFB93_RS10675	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JFB93_RS10685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFB93_RS10690	COG3099	Belongs to the UPF0263 family
JFB93_RS10695	COG4608	Belongs to the ABC transporter superfamily
JFB93_RS10705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFB93_RS10710	COG0601	transmembrane transport
JFB93_RS10720	COG4166	transmembrane transport
JFB93_RS10725	COG2095	MarC family integral membrane protein
JFB93_RS10730	COG1454	alcohol dehydrogenase
JFB93_RS10730	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS10735	COG1435	thymidine kinase activity
JFB93_RS10740	COG2916	Histone family protein nucleoid-structuring protein H-NS
JFB93_RS10745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JFB93_RS10750	COG0745	RESPONSE REGULATOR receiver
JFB93_RS10755	COG3012	SEC-C Motif Domain Protein
JFB93_RS10760	COG0788	formyltetrahydrofolate deformylase activity
JFB93_RS10770	COG0583	DNA-binding transcription factor activity
JFB93_RS10775	COG0708	Exodeoxyribonuclease III
JFB93_RS10780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFB93_RS10785	COG0709	Synthesizes selenophosphate from selenide and ATP
JFB93_RS10790	COG0778	Nitroreductase
JFB93_RS10795	COG0616	signal peptide processing
JFB93_RS10800	COG0252	asparaginase activity
JFB93_RS10805	COG1335	isochorismatase
JFB93_RS10810	COG3139	Protein of unknown function (DUF1315)
JFB93_RS10830	COG3713	MltA-interacting MipA family protein
JFB93_RS10835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JFB93_RS10840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JFB93_RS10850	COG2186	Transcriptional regulator
JFB93_RS10855	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JFB93_RS10860	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JFB93_RS10865	COG0243	molybdopterin cofactor binding
JFB93_RS10875	COG2076	Multidrug Resistance protein
JFB93_RS10895	COG1115	amino acid carrier protein
JFB93_RS10900	COG0501	Belongs to the peptidase M48B family
JFB93_RS10915	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JFB93_RS10920	COG1956	GAF domain-containing protein
JFB93_RS10925	COG2995	paraquat-inducible protein a
JFB93_RS10930	COG3008	intermembrane lipid transfer
JFB93_RS10945	COG1276	copper resistance
JFB93_RS10950	COG2372	response to copper ion
JFB93_RS10955	COG1528	Iron-storage protein
JFB93_RS10970	COG3140	Belongs to the UPF0181 family
JFB93_RS10980	COG0494	nUDIX hydrolase
JFB93_RS10985	COG1760	l-serine dehydratase
JFB93_RS10990	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS10990	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS10995	COG3715	PTS system
JFB93_RS11000	COG3716	PTS system mannose fructose sorbose family IID component
JFB93_RS11005	COG4811	Protein of unknown function (DUF986)
JFB93_RS11010	COG1971	Probably functions as a manganese efflux pump
JFB93_RS11015	COG2226	methyltransferase
JFB93_RS11020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JFB93_RS11030	COG2188	Transcriptional regulator
JFB93_RS11035	COG0730	response to heat
JFB93_RS11045	COG0702	epimerase
JFB93_RS11050	COG0659	secondary active sulfate transmembrane transporter activity
JFB93_RS11070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JFB93_RS11070	COG0519	Catalyzes the synthesis of GMP from XMP
JFB93_RS11075	COG0516	GMP reductase activity
JFB93_RS11075	COG0517	IMP dehydrogenase activity
JFB93_RS11080	COG1570	exodeoxyribonuclease VII activity
JFB93_RS11085	COG1629	transport
JFB93_RS11085	COG4206	TonB-dependent receptor
JFB93_RS11090	COG1770	oligopeptidase
JFB93_RS11105	COG0280	phosphate acetyltransferase
JFB93_RS11105	COG0281	malic enzyme
JFB93_RS11110	COG2197	response regulator
JFB93_RS11115	COG1393	Belongs to the ArsC family
JFB93_RS11120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JFB93_RS11125	COG1876	peptidase activity
JFB93_RS11130	COG2832	Protein of unknown function (DUF454)
JFB93_RS11140	COG1444	tRNA N-acetyltransferase activity
JFB93_RS11145	COG2707	UPF0756 membrane protein
JFB93_RS11165	COG1122	ATPase activity
JFB93_RS11170	COG1122	ATPase activity
JFB93_RS11175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JFB93_RS11180	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JFB93_RS11190	COG2716	regulation of RNA biosynthetic process
JFB93_RS11195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JFB93_RS11200	COG0628	permease
JFB93_RS11210	COG1393	Belongs to the ArsC family
JFB93_RS11215	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFB93_RS11220	COG2233	PERMEase
JFB93_RS11225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JFB93_RS11230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JFB93_RS11235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JFB93_RS11240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JFB93_RS11245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JFB93_RS11255	COG2239	Acts as a magnesium transporter
JFB93_RS11280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFB93_RS11285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFB93_RS11290	COG2205	protein histidine kinase activity
JFB93_RS11295	COG0745	RESPONSE REGULATOR receiver
JFB93_RS11300	COG0826	peptidase U32
JFB93_RS11305	COG1597	lipid kinase activity
JFB93_RS11315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JFB93_RS11320	COG1328	CTP reductase activity
JFB93_RS11330	COG1113	amino acid transport
JFB93_RS11340	COG2207	Transcriptional regulator
JFB93_RS11345	COG0561	phosphatase activity
JFB93_RS11350	COG0697	spore germination
JFB93_RS11355	COG1115	amino acid carrier protein
JFB93_RS11385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JFB93_RS11400	COG2226	methyltransferase
JFB93_RS11415	COG0840	transmembrane signaling receptor activity
JFB93_RS11445	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JFB93_RS11455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFB93_RS11460	COG2731	YhcH YjgK YiaL family protein
JFB93_RS11465	COG1737	Transcriptional regulator
JFB93_RS11470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JFB93_RS11475	COG0071	Belongs to the small heat shock protein (HSP20) family
JFB93_RS11500	COG3772	lysozyme
JFB93_RS11530	COG0582	viral genome integration into host DNA
JFB93_RS11535	COG0538	isocitrate dehydrogenase activity
JFB93_RS11640	COG0740	serine-type endopeptidase activity
JFB93_RS11685	COG3772	lysozyme
JFB93_RS11725	COG1403	HNH endonuclease
JFB93_RS11750	COG4725	Belongs to the MT-A70-like family
JFB93_RS11790	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JFB93_RS11795	COG2974	May be involved in recombination
JFB93_RS11815	COG0582	viral genome integration into host DNA
JFB93_RS11820	COG0538	isocitrate dehydrogenase activity
JFB93_RS11825	COG1187	pseudouridine synthase activity
JFB93_RS11835	COG0482	sulfurtransferase activity
JFB93_RS11840	COG2915	High frequency lysogenization protein hflD homolog
JFB93_RS11845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JFB93_RS11850	COG0745	RESPONSE REGULATOR receiver
JFB93_RS11860	COG2850	peptidyl-arginine hydroxylation
JFB93_RS11865	COG1280	lysine exporter protein (LysE YggA)
JFB93_RS11875	COG0300	oxidoreductase activity
JFB93_RS11885	COG2862	Uncharacterized protein family, UPF0114
JFB93_RS11895	COG4591	ABC-type transport system involved in lipoprotein release permease component
JFB93_RS11900	COG1136	(ABC) transporter
JFB93_RS11905	COG4591	ABC-type transport system involved in lipoprotein release permease component
JFB93_RS11910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JFB93_RS11920	COG1252	NADH dehydrogenase
JFB93_RS11925	COG0737	Belongs to the 5'-nucleotidase family
JFB93_RS11935	COG1472	Belongs to the glycosyl hydrolase 3 family
JFB93_RS11945	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
JFB93_RS11955	COG0537	adenosine 5'-monophosphoramidase activity
JFB93_RS11960	COG0084	hydrolase, TatD family'
JFB93_RS11965	COG0470	DNA polymerase III
JFB93_RS11970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JFB93_RS11975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JFB93_RS11980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JFB93_RS11985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFB93_RS11990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFB93_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS12005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JFB93_RS12010	COG0416	fatty acid biosynthetic process
JFB93_RS12015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JFB93_RS12020	COG1399	metal-binding, possibly nucleic acid-binding protein
JFB93_RS12025	COG0424	maF-like protein
JFB93_RS12030	COG0564	pseudouridine synthase activity
JFB93_RS12035	COG1530	ribonuclease E activity
JFB93_RS12045	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS12050	COG0243	molybdopterin cofactor binding
JFB93_RS12060	COG2926	Belongs to the UPF0265 family
JFB93_RS12065	COG2211	Major facilitator Superfamily
JFB93_RS12070	COG2925	Exonuclease
JFB93_RS12075	COG0277	FAD linked oxidase domain protein
JFB93_RS12085	COG0531	amino acid
JFB93_RS12095	COG4771	TonB-dependent receptor
JFB93_RS12100	COG1120	ATPase activity
JFB93_RS12105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFB93_RS12115	COG0833	amino acid
JFB93_RS12120	COG0583	DNA-binding transcription factor activity
JFB93_RS12125	COG2855	membrane
JFB93_RS12130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JFB93_RS12135	COG1105	Belongs to the carbohydrate kinase PfkB family
JFB93_RS12145	COG0814	amino acid
JFB93_RS12150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JFB93_RS12165	COG0791	NLP P60 protein
JFB93_RS12175	COG2814	Major facilitator Superfamily
JFB93_RS12185	COG1061	Type III restriction enzyme res subunit
JFB93_RS12190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JFB93_RS12195	COG3081	Nucleoid-associated protein
JFB93_RS12200	COG3082	Protein of unknown function (DUF1414)
JFB93_RS12205	COG3083	sulfuric ester hydrolase activity
JFB93_RS12265	COG1335	isochorismatase
JFB93_RS12280	COG0668	transmembrane transport
JFB93_RS12285	COG0243	molybdopterin cofactor binding
JFB93_RS12290	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS12295	COG3302	dmso reductase anchor subunit
JFB93_RS12300	COG3381	protein complex oligomerization
JFB93_RS12315	COG4770	biotin carboxylase activity
JFB93_RS12320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JFB93_RS12325	COG4336	lyase activity
JFB93_RS12330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JFB93_RS12335	COG1914	H( )-stimulated, divalent metal cation uptake system
JFB93_RS12345	COG1301	dicarboxylic acid transport
JFB93_RS12350	COG1560	Kdo2-lipid A biosynthetic process
JFB93_RS12365	COG2198	Histidine kinase
JFB93_RS12365	COG0642	Histidine kinase
JFB93_RS12375	COG0784	Response regulator, receiver
JFB93_RS12375	COG2205	protein histidine kinase activity
JFB93_RS12385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JFB93_RS12390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFB93_RS12395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFB93_RS12400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFB93_RS12405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFB93_RS12410	COG0814	amino acid
JFB93_RS12415	COG5464	transposase or invertase
JFB93_RS12435	COG1441	menaquinone biosynthetic process
JFB93_RS12440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JFB93_RS12450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JFB93_RS12455	COG1169	isochorismate synthase
JFB93_RS12470	COG1007	ATP synthesis coupled electron transport
JFB93_RS12475	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JFB93_RS12480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JFB93_RS12490	COG0839	Belongs to the complex I subunit 6 family
JFB93_RS12495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JFB93_RS12500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JFB93_RS12510	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JFB93_RS12520	COG0649	NAD binding
JFB93_RS12520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JFB93_RS12530	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JFB93_RS12535	COG0583	DNA-binding transcription factor activity
JFB93_RS12540	COG0436	Aminotransferase
JFB93_RS12545	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JFB93_RS12555	COG0490	domain, Protein
JFB93_RS12555	COG0471	metal ion transport
JFB93_RS12560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFB93_RS12565	COG3013	Belongs to the UPF0304 family
JFB93_RS12570	COG3092	negative regulation of chromosome organization
JFB93_RS12575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JFB93_RS12580	COG0280	phosphate acetyltransferase
JFB93_RS12580	COG0857	belongs to the CobB CobQ family
JFB93_RS12590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFB93_RS12605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JFB93_RS12610	COG1090	epimerase
JFB93_RS12620	COG3878	Protein conserved in bacteria
JFB93_RS12625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JFB93_RS12630	COG1286	toxin biosynthetic process
JFB93_RS12635	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JFB93_RS12640	COG0285	dihydrofolate synthase activity
JFB93_RS12645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JFB93_RS12650	COG0586	Pfam SNARE associated Golgi protein
JFB93_RS12655	COG0101	tRNA pseudouridine synthase activity
JFB93_RS12660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFB93_RS12665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JFB93_RS12675	COG0697	spore germination
JFB93_RS12690	COG0642	Histidine kinase
JFB93_RS12725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JFB93_RS12730	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JFB93_RS12730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JFB93_RS12745	COG3101	peptidyl-lysine hydroxylation
JFB93_RS12750	COG0730	response to heat
JFB93_RS12755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JFB93_RS12770	COG2986	histidine ammonia-lyase
JFB93_RS12775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JFB93_RS12785	COG1228	amidohydrolase
JFB93_RS12790	COG2840	Smr protein MutS2
JFB93_RS12795	COG2062	phosphohistidine phosphatase, SixA
JFB93_RS12800	COG1250	3-hydroxyacyl-CoA dehydrogenase
JFB93_RS12800	COG1024	Enoyl-CoA hydratase
JFB93_RS12805	COG0183	Belongs to the thiolase family
JFB93_RS12810	COG3691	Protein conserved in bacteria
JFB93_RS12815	COG2067	long-chain fatty acid transport protein
JFB93_RS12835	COG3722	fumarate hydratase activity
JFB93_RS12840	COG0246	Mannitol dehydrogenase
JFB93_RS12845	COG2213	PTS system mannitol-specific
JFB93_RS12845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS12905	COG2072	flavoprotein involved in K transport
JFB93_RS12910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JFB93_RS12915	COG2011	ABC-type metal ion transport system permease component
JFB93_RS12920	COG1396	sequence-specific DNA binding
JFB93_RS12965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JFB93_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS12990	COG3530	Putative quorum-sensing-regulated virulence factor
JFB93_RS12995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFB93_RS13000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JFB93_RS13005	COG3115	cell septum assembly
JFB93_RS13010	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JFB93_RS13020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS13025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JFB93_RS13030	COG2190	(PTS) system
JFB93_RS13035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JFB93_RS13040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JFB93_RS13045	COG4208	sulfate ABC transporter
JFB93_RS13055	COG4150	thiosulfate binding
JFB93_RS13060	COG2837	iron assimilation
JFB93_RS13070	COG0456	acetyltransferase
JFB93_RS13075	COG0408	coproporphyrinogen oxidase activity
JFB93_RS13095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JFB93_RS13100	COG2976	Protein conserved in bacteria
JFB93_RS13105	COG0124	histidyl-tRNA synthetase
JFB93_RS13120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JFB93_RS13125	COG0105	UTP biosynthetic process
JFB93_RS13130	COG4953	penicillin-binding protein 1C
JFB93_RS13135	COG2373	Large extracellular alpha-helical protein
JFB93_RS13145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JFB93_RS13150	COG2975	iron-sulfur cluster assembly
JFB93_RS13155	COG0633	Ferredoxin
JFB93_RS13160	COG0443	Heat shock 70 kDa protein
JFB93_RS13170	COG0316	Belongs to the HesB IscA family
JFB93_RS13175	COG0822	iron-sulfur transferase activity
JFB93_RS13180	COG1104	cysteine desulfurase activity
JFB93_RS13185	COG1959	2 iron, 2 sulfur cluster binding
JFB93_RS13190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JFB93_RS13195	COG0483	inositol monophosphate 1-phosphatase activity
JFB93_RS13200	COG1063	alcohol dehydrogenase
JFB93_RS13205	COG1802	Transcriptional regulator
JFB93_RS13215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JFB93_RS13220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFB93_RS13220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JFB93_RS13225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JFB93_RS13230	COG2814	Major facilitator Superfamily
JFB93_RS13235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JFB93_RS13240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFB93_RS13240	COG1017	nitric oxide dioxygenase activity
JFB93_RS13245	COG0347	Belongs to the P(II) protein family
JFB93_RS13250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JFB93_RS13250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JFB93_RS13255	COG2204	response regulator
JFB93_RS13260	COG3170	Tfp pilus assembly protein FimV
JFB93_RS13265	COG2205	protein histidine kinase activity
JFB93_RS13270	COG2867	negative regulation of translational initiation
JFB93_RS13270	COG2226	methyltransferase
JFB93_RS13285	COG2271	Major facilitator Superfamily
JFB93_RS13290	COG1840	ABC-type Fe3 transport system, periplasmic component
JFB93_RS13300	COG3842	ATPase activity
JFB93_RS13315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JFB93_RS13345	COG0561	phosphatase activity
JFB93_RS13350	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JFB93_RS13355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JFB93_RS13355	COG0047	phosphoribosylformylglycinamidine synthase activity
JFB93_RS13360	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JFB93_RS13385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JFB93_RS13390	COG0736	holo-[acyl-carrier-protein] synthase activity
JFB93_RS13395	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JFB93_RS13400	COG1381	Involved in DNA repair and RecF pathway recombination
JFB93_RS13405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JFB93_RS13410	COG0571	ribonuclease III activity
JFB93_RS13425	COG3086	response to oxidative stress
JFB93_RS13430	COG3026	antisigma factor binding
JFB93_RS13445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JFB93_RS13450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JFB93_RS13460	COG0010	Belongs to the arginase family
JFB93_RS13465	COG0786	glutamate:sodium symporter activity
JFB93_RS13470	COG0513	Belongs to the DEAD box helicase family
JFB93_RS13485	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JFB93_RS13490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JFB93_RS13495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JFB93_RS13500	COG0497	DNA recombination
JFB93_RS13505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JFB93_RS13510	COG2914	Belongs to the UPF0125 (RnfH) family
JFB93_RS13515	COG2867	negative regulation of translational initiation
JFB93_RS13630	COG2369	cell adhesion
JFB93_RS13670	COG3772	lysozyme
JFB93_RS13730	COG0305	Participates in initiation and elongation during chromosome replication
JFB93_RS13800	COG0582	viral genome integration into host DNA
JFB93_RS13840	COG0583	DNA-binding transcription factor activity
JFB93_RS13865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JFB93_RS13885	COG2211	Major facilitator Superfamily
JFB93_RS13890	COG1285	pathogenesis
JFB93_RS13900	COG3772	lysozyme
JFB93_RS13970	COG1609	Transcriptional regulator
JFB93_RS13975	COG2017	converts alpha-aldose to the beta-anomer
JFB93_RS13980	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JFB93_RS13990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JFB93_RS13995	COG1414	Transcriptional regulator
JFB93_RS14020	COG2271	Major facilitator Superfamily
JFB93_RS14025	COG0702	epimerase
JFB93_RS14030	COG4256	Hemin uptake protein
JFB93_RS14045	COG3720	iron ion transport
JFB93_RS14050	COG4558	Periplasmic binding protein
JFB93_RS14055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFB93_RS14060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JFB93_RS14075	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JFB93_RS14095	COG3239	Fatty acid desaturase
JFB93_RS14120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JFB93_RS14125	COG0372	Belongs to the citrate synthase family
JFB93_RS14130	COG2079	MmgE PrpD family protein
JFB93_RS14135	COG2017	converts alpha-aldose to the beta-anomer
JFB93_RS14145	COG0589	response to stress
JFB93_RS14180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JFB93_RS14190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JFB93_RS14195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JFB93_RS14200	COG4974	Belongs to the 'phage' integrase family
JFB93_RS14205	COG0716	FMN binding
JFB93_RS14215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JFB93_RS14220	COG0354	folic acid binding
JFB93_RS14235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JFB93_RS14235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JFB93_RS14240	COG0509	glycine decarboxylation via glycine cleavage system
JFB93_RS14245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JFB93_RS14250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFB93_RS14255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JFB93_RS14260	COG0006	proline dipeptidase activity
JFB93_RS14265	COG3079	Belongs to the UPF0149 family
JFB93_RS14270	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JFB93_RS14280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JFB93_RS14285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JFB93_RS14290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JFB93_RS14295	COG0583	DNA-binding transcription factor activity
JFB93_RS14305	COG1279	arginine transmembrane transporter activity
JFB93_RS14310	COG0668	transmembrane transport
JFB93_RS14315	COG3112	Uncharacterised protein family (UPF0231)
JFB93_RS14330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFB93_RS14335	COG0508	dehydrogenase complex catalyzes the overall conversion of
JFB93_RS14340	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JFB93_RS14345	COG2186	Transcriptional regulator
JFB93_RS14355	COG3023	N-Acetylmuramoyl-L-alanine amidase
JFB93_RS14360	COG4969	Belongs to the N-Me-Phe pilin family
JFB93_RS14365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JFB93_RS14375	COG0237	dephospho-CoA kinase activity
JFB93_RS14380	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JFB93_RS14390	COG0494	nUDIX hydrolase
JFB93_RS14395	COG0653	protein targeting
JFB93_RS14410	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JFB93_RS14415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JFB93_RS14420	COG0849	cell division
JFB93_RS14425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JFB93_RS14430	COG1181	Belongs to the D-alanine--D-alanine ligase family
JFB93_RS14435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JFB93_RS14440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JFB93_RS14445	COG0772	Belongs to the SEDS family
JFB93_RS14450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JFB93_RS14455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JFB93_RS14460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JFB93_RS14465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JFB93_RS14470	COG0768	penicillin binding
JFB93_RS14475	COG3116	cell division
JFB93_RS14480	COG0275	rRNA processing
JFB93_RS14485	COG2001	Belongs to the MraZ family
JFB93_RS14500	COG0028	Belongs to the TPP enzyme family
JFB93_RS14505	COG1022	Amp-dependent synthetase and ligase
JFB93_RS14515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JFB93_RS14520	COG0473	3-isopropylmalate dehydrogenase activity
JFB93_RS14525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JFB93_RS14535	COG4533	DNA binding
JFB93_RS14540	COG3066	DNA modification
JFB93_RS14545	COG0861	Integral membrane protein TerC family
JFB93_RS14570	COG0010	Belongs to the arginase family
JFB93_RS14575	COG1166	arginine decarboxylase activity
JFB93_RS14580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JFB93_RS14595	COG0640	Transcriptional regulator
JFB93_RS14605	COG2239	Acts as a magnesium transporter
JFB93_RS14615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFB93_RS14620	COG1151	hydroxylamine reductase activity
JFB93_RS14645	COG2353	YceI-like domain
JFB93_RS14650	COG3038	cytochrome b561
JFB93_RS14675	COG3718	enzyme involved in inositol metabolism
JFB93_RS14685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFB93_RS14700	COG2814	Major facilitator Superfamily
JFB93_RS14705	COG0673	inositol 2-dehydrogenase activity
JFB93_RS14735	COG2207	Transcriptional regulator
JFB93_RS14735	COG3708	Transcriptional regulator
JFB93_RS14750	COG3088	subunit of a heme lyase
JFB93_RS14750	COG4235	cytochrome complex assembly
JFB93_RS14755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JFB93_RS14760	COG1138	Cytochrome C-type biogenesis protein
JFB93_RS14770	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFB93_RS14775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JFB93_RS14780	COG3005	denitrification pathway
JFB93_RS14785	COG3043	anaerobic respiration
JFB93_RS14790	COG0348	domain, Protein
JFB93_RS14795	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS14805	COG3062	negative regulation of establishment of protein localization
JFB93_RS14810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JFB93_RS14810	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
JFB93_RS14820	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JFB93_RS14825	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS14830	COG3301	Polysulphide reductase, NrfD
JFB93_RS14835	COG1138	Cytochrome C-type biogenesis protein
JFB93_RS14840	COG4235	cytochrome complex assembly
JFB93_RS14850	COG0443	Heat shock 70 kDa protein
JFB93_RS14865	COG0583	DNA-binding transcription factor activity
JFB93_RS14885	COG3381	protein complex oligomerization
JFB93_RS14895	COG0626	cystathionine gamma-synthase activity
JFB93_RS14900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JFB93_RS14910	COG0626	cystathionine gamma-synthase activity
JFB93_RS14915	COG0513	Belongs to the DEAD box helicase family
JFB93_RS14930	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JFB93_RS14935	COG0402	S-adenosylhomocysteine deaminase activity
JFB93_RS14940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JFB93_RS14970	COG3119	arylsulfatase activity
JFB93_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS14990	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JFB93_RS15000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS15000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS15005	COG3716	PTS system mannose fructose sorbose family IID component
JFB93_RS15010	COG3715	PTS system
JFB93_RS15015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JFB93_RS15020	COG2222	sugar isomerase
JFB93_RS15030	COG1349	DNA-binding transcription factor activity
JFB93_RS15035	COG0641	radical SAM
JFB93_RS15040	COG3119	arylsulfatase activity
JFB93_RS15065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JFB93_RS15080	COG0640	Transcriptional regulator
JFB93_RS15105	COG1566	PFAM secretion protein HlyD family protein
JFB93_RS15130	COG2226	methyltransferase
JFB93_RS15155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JFB93_RS15160	COG2501	S4 domain
JFB93_RS15165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS15165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS15170	COG1105	Belongs to the carbohydrate kinase PfkB family
JFB93_RS15175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JFB93_RS15175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JFB93_RS15175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JFB93_RS15180	COG0215	cysteine-tRNA ligase activity
JFB93_RS15185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JFB93_RS15190	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFB93_RS15195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JFB93_RS15200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JFB93_RS15215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JFB93_RS15220	COG4181	ATPase activity
JFB93_RS15225	COG2755	lipolytic protein G-D-S-L family
JFB93_RS15230	COG0300	oxidoreductase activity
JFB93_RS15235	COG3118	belongs to the thioredoxin family
JFB93_RS15240	COG0330	HflC and HflK could
JFB93_RS15245	COG1585	Membrane protein implicated in regulation of membrane protease activity
JFB93_RS15255	COG2217	Heavy metal translocating P-type atpase
JFB93_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS15270	COG2271	Major facilitator Superfamily
JFB93_RS15275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JFB93_RS15280	COG0129	dihydroxy-acid dehydratase activity
JFB93_RS15290	COG0800	Aldolase
JFB93_RS15295	COG3734	2-keto-3-deoxy-galactonokinase
JFB93_RS15300	COG2186	Transcriptional regulator
JFB93_RS15305	COG3247	response to pH
JFB93_RS15310	COG3735	TraB family
JFB93_RS15325	COG0737	Belongs to the 5'-nucleotidase family
JFB93_RS15330	COG2223	nitrite transmembrane transporter activity
JFB93_RS15335	COG4651	solute:proton antiporter activity
JFB93_RS15335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JFB93_RS15350	COG1349	DNA-binding transcription factor activity
JFB93_RS15365	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JFB93_RS15375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFB93_RS15380	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
JFB93_RS15390	COG0563	adenylate kinase activity
JFB93_RS15395	COG0326	Molecular chaperone. Has ATPase activity
JFB93_RS15400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JFB93_RS15405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JFB93_RS15410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JFB93_RS15415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JFB93_RS15430	COG1196	nuclear chromosome segregation
JFB93_RS15430	COG3264	Mechanosensitive ion channel
JFB93_RS15435	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JFB93_RS15440	COG1309	transcriptional regulator
JFB93_RS15445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFB93_RS15450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFB93_RS15460	COG3210	domain, Protein
JFB93_RS15460	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JFB93_RS15460	COG3064	Membrane
JFB93_RS15465	COG0471	metal ion transport
JFB93_RS15475	COG0148	phosphopyruvate hydratase activity
JFB93_RS15480	COG0504	CTP synthase activity
JFB93_RS15485	COG3956	TIGRFAM MazG family protein
JFB93_RS15495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFB93_RS15500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFB93_RS15510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JFB93_RS15515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JFB93_RS15525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JFB93_RS15530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JFB93_RS15535	COG1643	Atp-dependent helicase
JFB93_RS15540	COG1489	DNA binding
JFB93_RS15555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JFB93_RS15560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JFB93_RS15565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JFB93_RS15570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JFB93_RS15595	COG3121	Chaperone
JFB93_RS15605	COG0842	Transport permease protein
JFB93_RS15610	COG1131	(ABC) transporter
JFB93_RS15615	COG0288	reversible hydration of carbon dioxide
JFB93_RS15620	COG3210	domain, Protein
JFB93_RS15630	COG2132	Multicopper oxidase
JFB93_RS15650	COG5441	Belongs to the UPF0261 family
JFB93_RS15655	COG5564	TIM-barrel signal transduction protein
JFB93_RS15670	COG0673	inositol 2-dehydrogenase activity
JFB93_RS15675	COG0534	Mate efflux family protein
JFB93_RS15685	COG0523	cobalamin synthesis protein
JFB93_RS15690	COG2879	small protein
JFB93_RS15695	COG1966	Carbon starvation protein
JFB93_RS15735	COG2962	Rard protein
JFB93_RS15740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFB93_RS15755	COG4566	intracellular signal transduction
JFB93_RS15765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JFB93_RS15780	COG4633	Protein conserved in bacteria
JFB93_RS15795	COG2837	iron assimilation
JFB93_RS15810	COG0583	DNA-binding transcription factor activity
JFB93_RS15820	COG2252	PERMEase
JFB93_RS15840	COG0786	glutamate:sodium symporter activity
JFB93_RS15845	COG0583	DNA-binding transcription factor activity
JFB93_RS15855	COG0251	oxidation-reduction process
JFB93_RS15880	COG2010	Cytochrome c
JFB93_RS15880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JFB93_RS15895	COG2010	Cytochrome c
JFB93_RS15895	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JFB93_RS15930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JFB93_RS15945	COG4942	peptidase
JFB93_RS15945	COG1388	LysM domain
JFB93_RS15955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JFB93_RS15970	COG0585	pseudouridine synthase activity
JFB93_RS15975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JFB93_RS15980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JFB93_RS15985	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JFB93_RS15990	COG0529	Catalyzes the synthesis of activated sulfate
JFB93_RS15995	COG2895	sulfate adenylyltransferase (ATP) activity
JFB93_RS16000	COG0175	sulfate reduction
JFB93_RS16005	COG1648	precorrin-2 dehydrogenase activity
JFB93_RS16005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JFB93_RS16015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JFB93_RS16020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JFB93_RS16025	COG0720	synthase
JFB93_RS16030	COG3477	response to acidic pH
JFB93_RS16035	COG0602	queuosine metabolic process
JFB93_RS16060	COG3738	Protein conserved in bacteria
JFB93_RS16065	COG3021	interspecies interaction between organisms
JFB93_RS16095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JFB93_RS16100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JFB93_RS16105	COG2011	ABC-type metal ion transport system permease component
JFB93_RS16110	COG1464	Belongs to the NlpA lipoprotein family
JFB93_RS16120	COG1720	tRNA m6t6A37 methyltransferase activity
JFB93_RS16125	COG0442	prolyl-tRNA aminoacylation
JFB93_RS16135	COG1486	melibiose metabolic process
JFB93_RS16140	COG2169	Transcriptional regulator
JFB93_RS16140	COG1917	Cupin 2, conserved barrel domain protein
JFB93_RS16145	COG1447	Phosphotransferase system cellobiose-specific component IIA
JFB93_RS16150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFB93_RS16155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JFB93_RS16160	COG3015	lipoprotein NlpE involved in copper resistance
JFB93_RS16165	COG4568	rho-dependent transcription termination
JFB93_RS16170	COG0037	tRNA processing
JFB93_RS16175	COG0697	spore germination
JFB93_RS16190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JFB93_RS16195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFB93_RS16200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFB93_RS16205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JFB93_RS16210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JFB93_RS16220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JFB93_RS16225	COG0750	zinc metalloprotease
JFB93_RS16230	COG0575	Belongs to the CDS family
JFB93_RS16245	COG0233	cytoplasmic translational termination
JFB93_RS16250	COG0528	UMP kinase activity
JFB93_RS16255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JFB93_RS16270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JFB93_RS16285	COG0716	FMN binding
JFB93_RS16290	COG0564	pseudouridine synthase activity
JFB93_RS16295	COG3098	single-species biofilm formation
JFB93_RS16300	COG2990	Protein conserved in bacteria
JFB93_RS16310	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JFB93_RS16310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JFB93_RS16315	COG1611	Belongs to the LOG family
JFB93_RS16330	COG2363	Small membrane protein
JFB93_RS16335	COG0583	DNA-binding transcription factor activity
JFB93_RS16340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JFB93_RS16345	COG2166	iron-sulfur cluster assembly
JFB93_RS16350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JFB93_RS16355	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JFB93_RS16375	COG0860	N-Acetylmuramoyl-L-alanine amidase
JFB93_RS16380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JFB93_RS16380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JFB93_RS16390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JFB93_RS16395	COG1074	ATP-dependent DNA helicase activity
JFB93_RS16405	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JFB93_RS16420	COG4795	General secretion pathway protein
JFB93_RS16430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JFB93_RS16435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JFB93_RS16440	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
JFB93_RS16445	COG0494	nUDIX hydrolase
JFB93_RS16450	COG4143	(ABC) transporter
JFB93_RS16455	COG1178	ABC-type Fe3 transport system permease component
JFB93_RS16460	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JFB93_RS16465	COG0417	DNA replication proofreading
JFB93_RS16470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JFB93_RS16475	COG0564	pseudouridine synthase activity
JFB93_RS16480	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JFB93_RS16485	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JFB93_RS16490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JFB93_RS16495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JFB93_RS16500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JFB93_RS16505	COG2967	ApaG domain
JFB93_RS16510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JFB93_RS16515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JFB93_RS16520	COG1280	lysine exporter protein (LysE YggA)
JFB93_RS16530	COG2132	Multicopper oxidase
JFB93_RS16535	COG0204	Acyl-transferase
JFB93_RS16545	COG0187	DNA topoisomerase II activity
JFB93_RS16550	COG3150	esterase
JFB93_RS16555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JFB93_RS16560	COG0494	nUDIX hydrolase
JFB93_RS16570	COG5463	Belongs to the UPF0441 family
JFB93_RS16575	COG0754	glutathionylspermidine amidase activity
JFB93_RS16580	COG3384	dioxygenase
JFB93_RS16585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JFB93_RS16595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JFB93_RS16595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JFB93_RS16600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JFB93_RS16605	COG3025	triphosphatase activity
JFB93_RS16610	COG4991	sh3 domain protein
JFB93_RS16620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JFB93_RS16625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JFB93_RS16630	COG0840	transmembrane signaling receptor activity
JFB93_RS16635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JFB93_RS16640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JFB93_RS16645	COG0358	DNA primase activity
JFB93_RS16655	COG0477	Major facilitator Superfamily
JFB93_RS16665	COG0477	Major facilitator Superfamily
JFB93_RS16690	COG2226	methyltransferase
JFB93_RS16700	COG1120	ATPase activity
JFB93_RS16705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFB93_RS16730	COG1124	(ABC) transporter
JFB93_RS16745	COG0601	transmembrane transport
JFB93_RS16750	COG0747	negative chemotaxis
JFB93_RS16780	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JFB93_RS16785	COG0830	nickel cation binding
JFB93_RS16795	COG0309	Hydrogenase expression formation protein (HypE)
JFB93_RS16800	COG0409	Hydrogenase expression formation protein
JFB93_RS16805	COG0298	carbon dioxide binding
JFB93_RS16810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JFB93_RS16820	COG1773	rubredoxin
JFB93_RS16825	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JFB93_RS16830	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
JFB93_RS16835	COG5557	Pfam Polysulphide reductase, NrfD
JFB93_RS16840	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS16845	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
JFB93_RS16850	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
JFB93_RS16855	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JFB93_RS16865	COG1289	transmembrane transporter activity
JFB93_RS16890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFB93_RS16925	COG0446	pyridine nucleotide-disulphide oxidoreductase
JFB93_RS16925	COG1902	pentaerythritol trinitrate reductase activity
JFB93_RS16930	COG1469	GTP cyclohydrolase I activity
JFB93_RS16940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JFB93_RS16945	COG0861	Integral membrane protein TerC family
JFB93_RS16950	COG0586	Pfam SNARE associated Golgi protein
JFB93_RS16955	COG4575	ribosome binding
JFB93_RS16960	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
JFB93_RS16970	COG2259	Doxx family
JFB93_RS16975	COG0583	DNA-binding transcription factor activity
JFB93_RS16980	COG1741	Belongs to the pirin family
JFB93_RS16985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS16985	COG3711	transcriptional antiterminator
JFB93_RS17015	COG3964	amidohydrolase
JFB93_RS17030	COG0348	domain, Protein
JFB93_RS17040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JFB93_RS17050	COG0792	nuclease activity
JFB93_RS17055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JFB93_RS17060	COG2823	Periplasmic or secreted lipoprotein
JFB93_RS17065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JFB93_RS17070	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JFB93_RS17075	COG5002	protein histidine kinase activity
JFB93_RS17075	COG0784	Response regulator, receiver
JFB93_RS17075	COG2198	Histidine kinase
JFB93_RS17080	COG0493	'glutamate synthase
JFB93_RS17085	COG2969	positive regulation of protein catabolic process
JFB93_RS17090	COG0625	glutathione transferase activity
JFB93_RS17095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JFB93_RS17100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JFB93_RS17105	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JFB93_RS17110	COG3105	Protein conserved in bacteria
JFB93_RS17115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFB93_RS17120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFB93_RS17125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JFB93_RS17130	COG5007	Belongs to the BolA IbaG family
JFB93_RS17140	COG2854	intermembrane phospholipid transfer
JFB93_RS17145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JFB93_RS17150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JFB93_RS17155	COG1127	ABC transporter
JFB93_RS17160	COG0517	IMP dehydrogenase activity
JFB93_RS17160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JFB93_RS17165	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JFB93_RS17170	COG3117	lipopolysaccharide transmembrane transporter activity
JFB93_RS17175	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JFB93_RS17180	COG1137	ATPase activity
JFB93_RS17185	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JFB93_RS17190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JFB93_RS17200	COG1660	Displays ATPase and GTPase activities
JFB93_RS17205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JFB93_RS17210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JFB93_RS17215	COG0312	modulator of DNA gyrase
JFB93_RS17220	COG3028	Belongs to the UPF0307 family
JFB93_RS17245	COG2732	(Barnase) inhibitor
JFB93_RS17255	COG0312	modulator of DNA gyrase
JFB93_RS17260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JFB93_RS17265	COG3164	Protein of unknown function
JFB93_RS17275	COG0424	maF-like protein
JFB93_RS17280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JFB93_RS17285	COG1792	Involved in formation and maintenance of cell shape
JFB93_RS17290	COG1077	Cell shape determining protein MreB Mrl
JFB93_RS17295	COG0604	alcohol dehydrogenase
JFB93_RS17300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JFB93_RS17305	COG0511	ligase activity, forming carbon-carbon bonds
JFB93_RS17310	COG0439	Biotin carboxylase
JFB93_RS17315	COG0641	radical SAM
JFB93_RS17320	COG2188	Transcriptional regulator
JFB93_RS17335	COG2149	membrane
JFB93_RS17345	COG3924	membrane
JFB93_RS17350	COG4145	pantothenate transmembrane transporter activity
JFB93_RS17355	COG2264	protein methyltransferase activity
JFB93_RS17360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JFB93_RS17365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JFB93_RS17385	COG3188	usher protein
JFB93_RS17390	COG3121	Chaperone
JFB93_RS17405	COG3539	Fimbrial protein
JFB93_RS17430	COG0590	tRNA wobble adenosine to inosine editing
JFB93_RS17435	COG0840	transmembrane signaling receptor activity
JFB93_RS17440	COG0814	amino acid
JFB93_RS17495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JFB93_RS17500	COG1960	acyl-CoA dehydrogenase activity
JFB93_RS17510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JFB93_RS17525	COG0411	ABC transporter
JFB93_RS17530	COG4177	L-phenylalanine transmembrane transporter activity
JFB93_RS17535	COG0559	Belongs to the binding-protein-dependent transport system permease family
JFB93_RS17540	COG0683	leucine binding
JFB93_RS17550	COG0346	lactoylglutathione lyase activity
JFB93_RS17560	COG2177	Part of the ABC transporter FtsEX involved in
JFB93_RS17565	COG2884	Cell division ATP-binding protein ftsE
JFB93_RS17570	COG0552	protein localization to endoplasmic reticulum
JFB93_RS17570	COG0552	protein localization to endoplasmic reticulum
JFB93_RS17575	COG0742	ribosomal rna small subunit methyltransferase
JFB93_RS17580	COG3776	membrane
JFB93_RS17590	COG3714	YhhN family
JFB93_RS17600	COG5464	transposase or invertase
JFB93_RS17605	COG0425	Belongs to the sulfur carrier protein TusA family
JFB93_RS17610	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JFB93_RS17615	COG0247	lactate metabolic process
JFB93_RS17625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JFB93_RS17630	COG2271	Major facilitator Superfamily
JFB93_RS17635	COG0584	glycerophosphoryl diester phosphodiesterase
JFB93_RS17645	COG1053	succinate dehydrogenase
JFB93_RS17650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JFB93_RS17655	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JFB93_RS17660	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JFB93_RS17680	COG1309	transcriptional regulator
JFB93_RS17685	COG4774	siderophore transport
JFB93_RS17700	COG2076	Multidrug Resistance protein
JFB93_RS17710	COG1966	Carbon starvation protein
JFB93_RS17715	COG2879	small protein
JFB93_RS17720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JFB93_RS17725	COG1509	lysine 2,3-aminomutase activity
JFB93_RS17755	COG0459	protein refolding
JFB93_RS17770	COG1027	Aspartate ammonia-lyase
JFB93_RS17775	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JFB93_RS17785	COG1309	transcriptional regulator
JFB93_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS17835	COG3188	usher protein
JFB93_RS17860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JFB93_RS17875	COG2207	Transcriptional regulator
JFB93_RS17875	COG3708	Transcriptional regulator
JFB93_RS17880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFB93_RS17900	COG4869	propanediol catabolic process
JFB93_RS17910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JFB93_RS17915	COG1882	Formate acetyltransferase
JFB93_RS17930	COG1454	alcohol dehydrogenase
JFB93_RS17930	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS17970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JFB93_RS17975	COG1177	transmembrane transport
JFB93_RS17990	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JFB93_RS17990	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JFB93_RS18005	COG3121	Chaperone
JFB93_RS18010	COG3188	usher protein
JFB93_RS18030	COG0583	DNA-binding transcription factor activity
JFB93_RS18040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFB93_RS18065	COG3239	Fatty acid desaturase
JFB93_RS18070	COG0726	polysaccharide deacetylase
JFB93_RS18075	COG4948	Mandelate Racemase Muconate Lactonizing
JFB93_RS18080	COG2271	Major facilitator Superfamily
JFB93_RS18095	COG2721	sulfolactate sulfo-lyase activity
JFB93_RS18105	COG1349	DNA-binding transcription factor activity
JFB93_RS18115	COG1129	ABC transporter
JFB93_RS18120	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFB93_RS18125	COG1172	Belongs to the binding-protein-dependent transport system permease family
JFB93_RS18130	COG3623	hexulose-6-phosphate isomerase
JFB93_RS18135	COG1070	Carbohydrate kinase
JFB93_RS18140	COG0583	DNA-binding transcription factor activity
JFB93_RS18145	COG2610	gluconate transmembrane transporter activity
JFB93_RS18150	COG3048	D-serine ammonia-lyase activity
JFB93_RS18155	COG1363	Peptidase, m42
JFB93_RS18160	COG2188	Transcriptional regulator
JFB93_RS18170	COG0444	Belongs to the ABC transporter superfamily
JFB93_RS18175	COG0601	transmembrane transport
JFB93_RS18180	COG0747	negative chemotaxis
JFB93_RS18190	COG3573	Dehydrogenase
JFB93_RS18205	COG4604	ABC transporter, ATP-binding protein
JFB93_RS18210	COG4605	iron ion homeostasis
JFB93_RS18215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFB93_RS18220	COG4607	ABC-type enterochelin transport system periplasmic component
JFB93_RS18245	COG3539	Fimbrial protein
JFB93_RS18255	COG3121	Chaperone
JFB93_RS18260	COG3188	usher protein
JFB93_RS18275	COG2181	nitrate reductase activity
JFB93_RS18280	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JFB93_RS18285	COG1140	nitrate reductase beta subunit
JFB93_RS18290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JFB93_RS18295	COG2223	nitrite transmembrane transporter activity
JFB93_RS18300	COG3850	Histidine kinase
JFB93_RS18305	COG2197	response regulator
JFB93_RS18310	COG3835	regulator
JFB93_RS18315	COG1929	Belongs to the glycerate kinase type-1 family
JFB93_RS18325	COG0183	Belongs to the thiolase family
JFB93_RS18330	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS18345	COG0625	glutathione transferase activity
JFB93_RS18355	COG1840	ABC-type Fe3 transport system, periplasmic component
JFB93_RS18360	COG3842	ATPase activity
JFB93_RS18375	COG1858	cytochrome C peroxidase
JFB93_RS18385	COG3302	dmso reductase anchor subunit
JFB93_RS18390	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS18395	COG0243	molybdopterin cofactor binding
JFB93_RS18410	COG2146	nitrite reductase [NAD(P)H] activity
JFB93_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS18430	COG1414	Transcriptional regulator
JFB93_RS18445	COG2271	Major facilitator Superfamily
JFB93_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
JFB93_RS18465	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
JFB93_RS18470	COG1012	belongs to the aldehyde dehydrogenase family
JFB93_RS18480	COG2390	Transcriptional regulator
JFB93_RS18540	COG3188	usher protein
JFB93_RS18615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JFB93_RS18645	COG0582	viral genome integration into host DNA
JFB93_RS18655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JFB93_RS18670	COG0795	lipopolysaccharide-transporting ATPase activity
JFB93_RS18675	COG0795	lipopolysaccharide-transporting ATPase activity
JFB93_RS18680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JFB93_RS18685	COG2927	DNA polymerase III (CHI subunit)
JFB93_RS18690	COG0525	valine-tRNA ligase activity
JFB93_RS18715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFB93_RS18735	COG0789	Transcriptional regulator
JFB93_RS18750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JFB93_RS18755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JFB93_RS18765	COG2188	Transcriptional regulator
JFB93_RS18800	COG0540	Belongs to the ATCase OTCase family
JFB93_RS18805	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JFB93_RS18810	COG0251	oxidation-reduction process
JFB93_RS18815	COG1328	CTP reductase activity
JFB93_RS18820	COG0602	queuosine metabolic process
JFB93_RS18825	COG3787	Belongs to the UPF0306 family
JFB93_RS18835	COG2827	Endonuclease containing a URI domain
JFB93_RS18840	COG3153	acetyltransferase
JFB93_RS18845	COG3154	lipid carrier protein
JFB93_RS18850	COG0826	peptidase U32
JFB93_RS18855	COG0826	peptidase U32
JFB93_RS18885	COG3275	phosphorelay sensor kinase activity
JFB93_RS18900	COG0513	Belongs to the DEAD box helicase family
JFB93_RS18920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JFB93_RS18925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JFB93_RS18930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JFB93_RS18935	COG0195	Participates in both transcription termination and antitermination
JFB93_RS18940	COG0779	Required for maturation of 30S ribosomal subunits
JFB93_RS18955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JFB93_RS18960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFB93_RS18965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JFB93_RS18970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JFB93_RS18975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JFB93_RS18980	COG1534	Rna-binding protein
JFB93_RS18990	COG2027	D-alanyl-D-alanine carboxypeptidase
JFB93_RS18995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JFB93_RS19000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JFB93_RS19005	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JFB93_RS19010	COG0142	geranyltranstransferase activity
JFB93_RS19025	COG3423	Transcriptional regulator
JFB93_RS19030	COG0039	L-malate dehydrogenase activity
JFB93_RS19035	COG1438	arginine binding
JFB93_RS19055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JFB93_RS19060	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JFB93_RS19070	COG2105	PFAM AIG2 family protein
JFB93_RS19080	COG0729	surface antigen
JFB93_RS19085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JFB93_RS19090	COG1253	flavin adenine dinucleotide binding
JFB93_RS19100	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JFB93_RS19105	COG0642	Histidine kinase
JFB93_RS19115	COG3111	PFAM Bacterial OB fold (BOF) protein
JFB93_RS19120	COG0494	nUDIX hydrolase
JFB93_RS19135	COG0579	oxidoreductase
JFB93_RS19145	COG0545	Peptidyl-prolyl cis-trans isomerase
JFB93_RS19150	COG3061	Opacity-associated protein A
JFB93_RS19155	COG2134	cdp-diacylglycerol pyrophosphatase
JFB93_RS19160	COG0359	binds to the 23S rRNA
JFB93_RS19165	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JFB93_RS19170	COG2965	DNA replication, synthesis of RNA primer
JFB93_RS19175	COG0360	Binds together with S18 to 16S ribosomal RNA
JFB93_RS19180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFB93_RS19185	COG0557	exoribonuclease II activity
JFB93_RS19190	COG1959	2 iron, 2 sulfur cluster binding
JFB93_RS19195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JFB93_RS19200	COG0330	HflC and HflK could
JFB93_RS19205	COG0330	HflC and HflK could
JFB93_RS19210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JFB93_RS19215	COG1923	regulation of RNA biosynthetic process
JFB93_RS19225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JFB93_RS19230	COG0860	N-Acetylmuramoyl-L-alanine amidase
JFB93_RS19235	COG0802	atpase or kinase
JFB93_RS19240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JFB93_RS19265	COG1162	GTPase activity
JFB93_RS19270	COG0688	phosphatidylethanolamine metabolic process
JFB93_RS19275	COG1511	domain protein
JFB93_RS19275	COG3264	Mechanosensitive ion channel
JFB93_RS19290	COG0561	phosphatase activity
JFB93_RS19295	COG2267	carboxylic ester hydrolase activity
JFB93_RS19300	COG0514	ATP-dependent DNA helicase (RecQ)
JFB93_RS19310	COG2050	protein possibly involved in aromatic compounds catabolism
JFB93_RS19320	COG0531	amino acid
JFB93_RS19330	COG1690	Belongs to the RtcB family
JFB93_RS19335	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JFB93_RS19355	COG0210	DNA helicase
JFB93_RS19360	COG1011	Hydrolase
JFB93_RS19375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JFB93_RS19380	COG5567	small periplasmic lipoprotein
JFB93_RS19385	COG1965	Belongs to the frataxin family
JFB93_RS19395	COG0181	hydroxymethylbilane synthase activity
JFB93_RS19405	COG2959	enzyme of heme biosynthesis
JFB93_RS19410	COG3071	HemY protein
JFB93_RS19450	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JFB93_RS19460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JFB93_RS19465	COG2244	polysaccharide biosynthetic process
JFB93_RS19470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JFB93_RS19480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JFB93_RS19485	COG1088	dTDP-glucose 4,6-dehydratase activity
JFB93_RS19490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JFB93_RS19495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JFB93_RS19500	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
JFB93_RS19505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JFB93_RS19510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JFB93_RS19515	COG3118	belongs to the thioredoxin family
JFB93_RS19520	COG0513	Belongs to the DEAD box helicase family
JFB93_RS19525	COG0248	Ppx GppA phosphatase
JFB93_RS19530	COG0210	DNA helicase
JFB93_RS19535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JFB93_RS19545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JFB93_RS19550	COG0129	dihydroxy-acid dehydratase activity
JFB93_RS19555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JFB93_RS19560	COG3978	acetolactate synthase activity
JFB93_RS19575	COG0606	chelatase, subunit chli
JFB93_RS19580	COG3085	chromosome segregation
JFB93_RS19585	COG0583	DNA-binding transcription factor activity
JFB93_RS19620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JFB93_RS19630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JFB93_RS19635	COG0009	L-threonylcarbamoyladenylate synthase
JFB93_RS19640	COG0551	DNA topoisomerase type I activity
JFB93_RS19645	COG0758	DNA mediated transformation
JFB93_RS19650	COG0242	peptide deformylase activity
JFB93_RS19655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JFB93_RS19660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JFB93_RS19660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JFB93_RS19665	COG0569	domain protein
JFB93_RS19675	COG3036	rescue of stalled ribosome
JFB93_RS19680	COG0789	Transcriptional regulator
JFB93_RS19695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JFB93_RS19705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JFB93_RS19710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JFB93_RS19715	COG0201	protein transport
JFB93_RS19720	COG0200	Binds to the 23S rRNA
JFB93_RS19725	COG1841	ribosomal large subunit assembly
JFB93_RS19730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JFB93_RS19735	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JFB93_RS19740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JFB93_RS19745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JFB93_RS19750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JFB93_RS19755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JFB93_RS19760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JFB93_RS19765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JFB93_RS19770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JFB93_RS19780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JFB93_RS19790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JFB93_RS19800	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JFB93_RS19805	COG0089	rRNA binding
JFB93_RS19810	COG0088	Forms part of the polypeptide exit tunnel
JFB93_RS19815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JFB93_RS19820	COG0051	transcription antitermination factor activity, RNA binding
JFB93_RS19825	COG2193	ferroxidase activity
JFB93_RS19860	COG1072	(Pantothenic acid kinase))
JFB93_RS19865	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JFB93_RS19865	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JFB93_RS19905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JFB93_RS19910	COG4206	TonB-dependent receptor
JFB93_RS19915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFB93_RS19930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JFB93_RS19950	COG0165	Argininosuccinate lyase
JFB93_RS19955	COG0137	argininosuccinate synthase activity
JFB93_RS19960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JFB93_RS19965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JFB93_RS19970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JFB93_RS19985	COG0076	glutamate decarboxylase activity
JFB93_RS19990	COG0531	amino acid
JFB93_RS19995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JFB93_RS20005	COG0527	aspartate kinase activity
JFB93_RS20005	COG0460	homoserine dehydrogenase
JFB93_RS20010	COG0626	cystathionine gamma-synthase activity
JFB93_RS20035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JFB93_RS20040	COG1609	Transcriptional regulator
JFB93_RS20045	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JFB93_RS20050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JFB93_RS20055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JFB93_RS20060	COG1575	Belongs to the MenA family. Type 1 subfamily
JFB93_RS20065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JFB93_RS20070	COG3074	FtsZ-dependent cytokinesis
JFB93_RS20080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JFB93_RS20090	COG2814	Major facilitator Superfamily
JFB93_RS20100	COG3152	Membrane
JFB93_RS20110	COG0149	triose-phosphate isomerase activity
JFB93_RS20120	COG1472	Belongs to the glycosyl hydrolase 3 family
JFB93_RS20130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JFB93_RS20135	COG0205	6-phosphofructokinase activity
JFB93_RS20140	COG4589	Belongs to the CDS family
JFB93_RS20150	COG0501	Belongs to the peptidase M48B family
JFB93_RS20160	COG3678	ATP-independent chaperone mediated protein folding
JFB93_RS20165	COG0745	RESPONSE REGULATOR receiver
JFB93_RS20170	COG2205	protein histidine kinase activity
JFB93_RS20185	COG2089	acid synthase
JFB93_RS20210	COG2244	polysaccharide biosynthetic process
JFB93_RS20225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFB93_RS20230	COG1596	polysaccharide export
JFB93_RS20235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JFB93_RS20240	COG3206	protein involved in exopolysaccharide biosynthesis
JFB93_RS20240	COG0489	protein tyrosine kinase activity
JFB93_RS20245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JFB93_RS20250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JFB93_RS20260	COG1045	serine acetyltransferase
JFB93_RS20265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JFB93_RS20275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFB93_RS20280	COG4942	peptidase
JFB93_RS20285	COG2861	carbohydrate metabolic process
JFB93_RS20290	COG1063	alcohol dehydrogenase
JFB93_RS20300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JFB93_RS20325	COG1519	Transferase
JFB93_RS20330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JFB93_RS20335	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JFB93_RS20345	COG1442	glycosyl transferase family 8
JFB93_RS20350	COG2194	sulfuric ester hydrolase activity
JFB93_RS20355	COG1442	glycosyl transferase family 8
JFB93_RS20360	COG1442	glycosyl transferase family 8
JFB93_RS20365	COG0515	serine threonine protein kinase
JFB93_RS20370	COG0438	transferase activity, transferring glycosyl groups
JFB93_RS20375	COG0859	PFAM glycosyl transferase family 9
JFB93_RS20380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JFB93_RS20385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JFB93_RS20390	COG2003	Belongs to the UPF0758 family
JFB93_RS20395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JFB93_RS20400	COG0756	dUTP diphosphatase activity
JFB93_RS20405	COG1309	transcriptional regulator
JFB93_RS20410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JFB93_RS20415	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JFB93_RS20420	COG1561	YicC-like family, N-terminal region
JFB93_RS20425	COG2211	Major facilitator Superfamily
JFB93_RS20450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JFB93_RS20465	COG1368	sulfuric ester hydrolase activity
JFB93_RS20470	COG3276	selenocysteine insertion sequence binding
JFB93_RS20475	COG1921	L-seryl-tRNASec selenium transferase activity
JFB93_RS20480	COG3058	Necessary for formate dehydrogenase activity
JFB93_RS20485	COG2186	Transcriptional regulator
JFB93_RS20490	COG2271	Major facilitator Superfamily
JFB93_RS20500	COG0246	Mannitol dehydrogenase
JFB93_RS20505	COG1904	glucuronate isomerase
JFB93_RS20520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JFB93_RS20525	COG0679	Auxin Efflux Carrier
JFB93_RS20530	COG0028	Belongs to the TPP enzyme family
JFB93_RS20540	COG2864	formate dehydrogenase
JFB93_RS20545	COG0437	4 iron, 4 sulfur cluster binding
JFB93_RS20555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JFB93_RS20575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JFB93_RS20580	COG0706	membrane insertase activity
JFB93_RS20585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JFB93_RS20590	COG0594	ribonuclease P activity
JFB93_RS20595	COG0230	Belongs to the bacterial ribosomal protein bL34 family