locus-tag	class	description
ACHL_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACHL_RS00015	COG0592	DNA-directed DNA polymerase activity
ACHL_RS00020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACHL_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACHL_RS00030	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ACHL_RS00035	COG0187	DNA topoisomerase II activity
ACHL_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACHL_RS00045	COG3266	domain, Protein
ACHL_RS00065	COG1215	transferase activity, transferring glycosyl groups
ACHL_RS00080	COG0705	Rhomboid family
ACHL_RS00085	COG2818	Glycosylase
ACHL_RS00095	COG3764	Sortase (surface protein transpeptidase)
ACHL_RS00110	COG2815	serine threonine protein kinase
ACHL_RS00110	COG0515	serine threonine protein kinase
ACHL_RS00115	COG0515	serine threonine protein kinase
ACHL_RS00135	COG1716	ATPase activity
ACHL_RS00140	COG1716	ATPase activity
ACHL_RS00150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACHL_RS00155	COG0747	negative chemotaxis
ACHL_RS00160	COG0601	transmembrane transport
ACHL_RS00165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACHL_RS00170	COG0444	Belongs to the ABC transporter superfamily
ACHL_RS00175	COG4608	Belongs to the ABC transporter superfamily
ACHL_RS00185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACHL_RS00190	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS00195	COG0583	DNA-binding transcription factor activity
ACHL_RS00230	COG1309	transcriptional regulator
ACHL_RS00245	COG0346	lactoylglutathione lyase activity
ACHL_RS00285	COG0277	FAD linked oxidase domain protein
ACHL_RS00295	COG1357	PFAM Pentapeptide repeats (8 copies)
ACHL_RS00300	COG0154	amidase activity
ACHL_RS00305	COG2957	Belongs to the agmatine deiminase family
ACHL_RS00315	COG1162	GTPase activity
ACHL_RS00335	COG3706	GGDEF domain
ACHL_RS00355	COG1609	Transcriptional regulator
ACHL_RS00370	COG0659	secondary active sulfate transmembrane transporter activity
ACHL_RS00375	COG0789	Transcriptional regulator
ACHL_RS00405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACHL_RS00415	COG1802	Transcriptional regulator
ACHL_RS00430	COG0596	Alpha beta hydrolase
ACHL_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS00445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS00450	COG0436	Aminotransferase
ACHL_RS00455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACHL_RS00485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACHL_RS00570	COG0673	inositol 2-dehydrogenase activity
ACHL_RS00580	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACHL_RS00600	COG2814	Major facilitator Superfamily
ACHL_RS00610	COG0673	inositol 2-dehydrogenase activity
ACHL_RS00625	COG0457	Tetratricopeptide repeat
ACHL_RS00640	COG1316	TRANSCRIPTIONal
ACHL_RS00670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACHL_RS00675	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS00680	COG0145	ligase activity
ACHL_RS00695	COG3962	Belongs to the TPP enzyme family
ACHL_RS00700	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS00705	COG0133	tryptophan synthase activity
ACHL_RS00710	COG0673	inositol 2-dehydrogenase activity
ACHL_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS00720	COG0129	dihydroxy-acid dehydratase activity
ACHL_RS00725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACHL_RS00735	COG0673	inositol 2-dehydrogenase activity
ACHL_RS00740	COG1129	ABC transporter
ACHL_RS00745	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACHL_RS00755	COG0247	lactate metabolic process
ACHL_RS00755	COG0277	FAD linked oxidase domain protein
ACHL_RS00775	COG4124	Belongs to the glycosyl hydrolase 26 family
ACHL_RS00780	COG5002	protein histidine kinase activity
ACHL_RS00860	COG2326	polyphosphate kinase activity
ACHL_RS00865	COG0667	Aldo Keto reductase
ACHL_RS00870	COG4770	biotin carboxylase activity
ACHL_RS00875	COG1984	allophanate hydrolase subunit 2
ACHL_RS00880	COG0477	Major facilitator Superfamily
ACHL_RS00885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACHL_RS00890	COG2186	Transcriptional regulator
ACHL_RS00910	COG1609	Transcriptional regulator
ACHL_RS00920	COG1957	nucleoside hydrolase
ACHL_RS00925	COG0477	Major facilitator Superfamily
ACHL_RS00930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACHL_RS00950	COG2610	gluconate transmembrane transporter activity
ACHL_RS00955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACHL_RS00960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACHL_RS00970	COG1929	Belongs to the glycerate kinase type-1 family
ACHL_RS00995	COG1846	Transcriptional regulator
ACHL_RS01010	COG1937	Protein conserved in bacteria
ACHL_RS01030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACHL_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS01075	COG2084	Dehydrogenase
ACHL_RS01080	COG0477	Major facilitator Superfamily
ACHL_RS01095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACHL_RS01100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACHL_RS01105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACHL_RS01110	COG0640	Transcriptional regulator
ACHL_RS01120	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACHL_RS01130	COG0464	growth
ACHL_RS01140	COG0561	phosphatase activity
ACHL_RS01150	COG0584	glycerophosphoryl diester phosphodiesterase
ACHL_RS01160	COG2200	EAL domain
ACHL_RS01160	COG2199	diguanylate cyclase activity
ACHL_RS01170	COG5002	protein histidine kinase activity
ACHL_RS01180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACHL_RS01190	COG1929	Belongs to the glycerate kinase type-1 family
ACHL_RS01210	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS01220	COG4702	Belongs to the UPF0303 family
ACHL_RS01230	COG0823	Involved in the tonB-independent uptake of proteins
ACHL_RS01245	COG0673	inositol 2-dehydrogenase activity
ACHL_RS01250	COG0673	inositol 2-dehydrogenase activity
ACHL_RS01260	COG0395	ABC-type sugar transport system, permease component
ACHL_RS01315	COG2233	PERMEase
ACHL_RS01320	COG0778	Nitroreductase
ACHL_RS01335	COG0583	DNA-binding transcription factor activity
ACHL_RS01350	COG2186	Transcriptional regulator
ACHL_RS01360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACHL_RS01370	COG5416	Lipopolysaccharide assembly protein A domain
ACHL_RS01390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACHL_RS01405	COG1597	lipid kinase activity
ACHL_RS01410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACHL_RS01435	COG0477	Major facilitator Superfamily
ACHL_RS01445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS01455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS01465	COG0601	transmembrane transport
ACHL_RS01470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACHL_RS01480	COG0561	phosphatase activity
ACHL_RS01500	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACHL_RS01535	COG0037	tRNA processing
ACHL_RS01550	COG1609	Transcriptional regulator
ACHL_RS01555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACHL_RS01560	COG0302	gtp cyclohydrolase
ACHL_RS01565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACHL_RS01570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACHL_RS01600	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACHL_RS01610	COG0693	protein deglycase activity
ACHL_RS01615	COG2814	Major facilitator Superfamily
ACHL_RS01630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACHL_RS01645	COG1506	peptidase
ACHL_RS01645	COG0823	Involved in the tonB-independent uptake of proteins
ACHL_RS01650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACHL_RS01655	COG2376	Dihydroxyacetone kinase
ACHL_RS01660	COG1461	Dihydroxyacetone kinase
ACHL_RS01690	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ACHL_RS01705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACHL_RS01720	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS01730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACHL_RS01735	COG0583	DNA-binding transcription factor activity
ACHL_RS01755	COG0589	response to stress
ACHL_RS01800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACHL_RS01810	COG0306	phosphate transporter
ACHL_RS01835	COG1609	Transcriptional regulator
ACHL_RS01850	COG1595	DNA-templated transcription, initiation
ACHL_RS01885	COG2160	L-arabinose isomerase activity
ACHL_RS01905	COG1609	Transcriptional regulator
ACHL_RS01925	COG0831	urea catabolic process
ACHL_RS01930	COG0832	Belongs to the urease beta subunit family
ACHL_RS01935	COG0804	urea catabolic process
ACHL_RS01940	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ACHL_RS01945	COG0830	nickel cation binding
ACHL_RS01950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACHL_RS01955	COG0829	nickel cation binding
ACHL_RS01960	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ACHL_RS01980	COG0395	ABC-type sugar transport system, permease component
ACHL_RS02005	COG3958	Transketolase
ACHL_RS02010	COG3959	Transketolase, thiamine diphosphate binding domain
ACHL_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS02030	COG2376	Dihydroxyacetone kinase
ACHL_RS02035	COG0698	ribose 5-phosphate isomerase
ACHL_RS02050	COG2272	Belongs to the type-B carboxylesterase lipase family
ACHL_RS02065	COG3845	ABC transporter
ACHL_RS02080	COG2723	6-phospho-beta-galactosidase activity
ACHL_RS02105	COG3250	beta-galactosidase activity
ACHL_RS02110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACHL_RS02125	COG3507	Belongs to the glycosyl hydrolase 43 family
ACHL_RS02135	COG0583	DNA-binding transcription factor activity
ACHL_RS02145	COG1414	Transcriptional regulator
ACHL_RS02150	COG3250	beta-galactosidase activity
ACHL_RS02175	COG1929	Belongs to the glycerate kinase type-1 family
ACHL_RS02180	COG1301	dicarboxylic acid transport
ACHL_RS02190	COG0583	DNA-binding transcription factor activity
ACHL_RS02200	COG0385	Bile acid
ACHL_RS02205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACHL_RS02210	COG0318	PFAM AMP-dependent synthetase and ligase
ACHL_RS02215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACHL_RS02225	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS02245	COG0110	maltose O-acetyltransferase activity
ACHL_RS02275	COG0436	Aminotransferase
ACHL_RS02280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACHL_RS02285	COG2826	transposase and inactivated derivatives, IS30 family
ACHL_RS02295	COG0583	DNA-binding transcription factor activity
ACHL_RS02300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACHL_RS02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACHL_RS02310	COG1984	allophanate hydrolase subunit 2
ACHL_RS02315	COG0477	Major facilitator Superfamily
ACHL_RS02320	COG4221	oxidoreductase activity
ACHL_RS02325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACHL_RS02330	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS02335	COG1063	alcohol dehydrogenase
ACHL_RS02350	COG0697	spore germination
ACHL_RS02360	COG0667	Aldo Keto reductase
ACHL_RS02370	COG0702	epimerase
ACHL_RS02385	COG2890	protein-(glutamine-N5) methyltransferase activity
ACHL_RS02415	COG0656	L-ascorbic acid biosynthetic process
ACHL_RS02420	COG3401	FG-GAP repeat protein
ACHL_RS02430	COG0667	Aldo Keto reductase
ACHL_RS02435	COG0656	L-ascorbic acid biosynthetic process
ACHL_RS02450	COG3360	Dodecin
ACHL_RS02455	COG3866	Pectate lyase
ACHL_RS02460	COG4677	pectinesterase activity
ACHL_RS02465	COG0395	ABC-type sugar transport system, permease component
ACHL_RS02470	COG1175	transmembrane transport
ACHL_RS02475	COG1653	transport
ACHL_RS02495	COG2186	Transcriptional regulator
ACHL_RS02505	COG2084	Dehydrogenase
ACHL_RS02510	COG2610	gluconate transmembrane transporter activity
ACHL_RS02540	COG0076	glutamate decarboxylase activity
ACHL_RS02545	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ACHL_RS02560	COG0300	oxidoreductase activity
ACHL_RS02570	COG0477	Major facilitator Superfamily
ACHL_RS02580	COG3285	dna ligase
ACHL_RS02580	COG1793	dna ligase
ACHL_RS02585	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ACHL_RS02605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACHL_RS02605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACHL_RS02605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACHL_RS02645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACHL_RS02655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACHL_RS02660	COG0509	glycine decarboxylation via glycine cleavage system
ACHL_RS02665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACHL_RS02670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACHL_RS02670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACHL_RS02675	COG1113	amino acid transport
ACHL_RS02685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACHL_RS02690	COG2733	membrane
ACHL_RS02700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACHL_RS02745	COG4122	O-methyltransferase activity
ACHL_RS02750	COG0783	Belongs to the Dps family
ACHL_RS02775	COG1295	ribonuclease BN
ACHL_RS02805	COG1191	sigma factor activity
ACHL_RS02810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACHL_RS02815	COG0859	PFAM glycosyl transferase family 9
ACHL_RS02825	COG0297	glycogen (starch) synthase activity
ACHL_RS02830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACHL_RS02835	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACHL_RS02835	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACHL_RS02850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACHL_RS02850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACHL_RS02870	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS02880	COG1733	regulation of RNA biosynthetic process
ACHL_RS02885	COG0702	epimerase
ACHL_RS02890	COG1280	lysine exporter protein (LysE YggA)
ACHL_RS02905	COG2318	DinB family
ACHL_RS02910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACHL_RS02920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACHL_RS02940	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS02945	COG0589	response to stress
ACHL_RS02965	COG3290	protein histidine kinase activity
ACHL_RS02975	COG0010	Belongs to the arginase family
ACHL_RS02985	COG2252	PERMEase
ACHL_RS03005	COG3848	Pyruvate phosphate dikinase
ACHL_RS03005	COG0574	Belongs to the PEP-utilizing enzyme family
ACHL_RS03025	COG0791	NLP P60 protein
ACHL_RS03025	COG3883	PFAM NLP P60 protein
ACHL_RS03050	COG1796	DNA polymerase
ACHL_RS03050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACHL_RS03110	COG0366	Alpha amylase catalytic
ACHL_RS03135	COG1609	Transcriptional regulator
ACHL_RS03170	COG0492	ferredoxin-NADP+ reductase activity
ACHL_RS03180	COG0586	Pfam SNARE associated Golgi protein
ACHL_RS03190	COG1960	acyl-CoA dehydrogenase activity
ACHL_RS03195	COG0789	Transcriptional regulator
ACHL_RS03205	COG1278	Cold shock
ACHL_RS03210	COG2197	response regulator
ACHL_RS03225	COG0666	response to abiotic stimulus
ACHL_RS03230	COG0183	Belongs to the thiolase family
ACHL_RS03240	COG2031	fatty acid transporter
ACHL_RS03245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACHL_RS03260	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACHL_RS03285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACHL_RS03285	COG0357	Ribosomal RNA small subunit methyltransferase G
ACHL_RS03290	COG0191	fructose-bisphosphate aldolase activity
ACHL_RS03330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACHL_RS03355	COG1832	CoA-binding protein
ACHL_RS03365	COG2315	Protein conserved in bacteria
ACHL_RS03385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACHL_RS03390	COG0047	phosphoribosylformylglycinamidine synthase activity
ACHL_RS03425	COG1846	Transcriptional regulator
ACHL_RS03445	COG1131	(ABC) transporter
ACHL_RS03460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACHL_RS03485	COG0386	Belongs to the glutathione peroxidase family
ACHL_RS03490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACHL_RS03495	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS03515	COG1309	transcriptional regulator
ACHL_RS03525	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS03540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACHL_RS03545	COG2807	transmembrane transport
ACHL_RS03550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACHL_RS03570	COG0642	Histidine kinase
ACHL_RS03575	COG0745	RESPONSE REGULATOR receiver
ACHL_RS03580	COG0477	Major facilitator Superfamily
ACHL_RS03590	COG1309	transcriptional regulator
ACHL_RS03600	COG0028	Belongs to the TPP enzyme family
ACHL_RS03605	COG0351	phosphomethylpyrimidine kinase
ACHL_RS03635	COG0343	queuine tRNA-ribosyltransferase activity
ACHL_RS03665	COG1621	beta-fructofuranosidase activity
ACHL_RS03670	COG3842	ATPase activity
ACHL_RS03695	COG1960	acyl-CoA dehydrogenase activity
ACHL_RS03710	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACHL_RS03720	COG0586	Pfam SNARE associated Golgi protein
ACHL_RS03725	COG0564	pseudouridine synthase activity
ACHL_RS03745	COG2364	Membrane
ACHL_RS03750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACHL_RS03755	COG1201	RNA secondary structure unwinding
ACHL_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS03810	COG2814	Major facilitator Superfamily
ACHL_RS03815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACHL_RS03825	COG1309	transcriptional regulator
ACHL_RS03840	COG2124	cytochrome p450
ACHL_RS03870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACHL_RS03890	COG1609	Transcriptional regulator
ACHL_RS03905	COG0747	negative chemotaxis
ACHL_RS03915	COG0444	Belongs to the ABC transporter superfamily
ACHL_RS03930	COG0673	inositol 2-dehydrogenase activity
ACHL_RS03940	COG1904	glucuronate isomerase
ACHL_RS03945	COG0246	Mannitol dehydrogenase
ACHL_RS03955	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS03990	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS04000	COG0671	phosphoesterase, PA-phosphatase related
ACHL_RS04005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACHL_RS04020	COG2205	protein histidine kinase activity
ACHL_RS04025	COG0745	RESPONSE REGULATOR receiver
ACHL_RS04035	COG2062	phosphohistidine phosphatase, SixA
ACHL_RS04040	COG0583	DNA-binding transcription factor activity
ACHL_RS04055	COG1309	transcriptional regulator
ACHL_RS04060	COG1511	domain protein
ACHL_RS04080	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ACHL_RS04085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACHL_RS04085	COG1017	nitric oxide dioxygenase activity
ACHL_RS04090	COG1959	2 iron, 2 sulfur cluster binding
ACHL_RS04100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACHL_RS04105	COG0514	ATP-dependent DNA helicase (RecQ)
ACHL_RS04125	COG1505	serine-type exopeptidase activity
ACHL_RS04140	COG0737	Belongs to the 5'-nucleotidase family
ACHL_RS04155	COG3321	synthase
ACHL_RS04155	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS04155	COG0604	alcohol dehydrogenase
ACHL_RS04165	COG0577	efflux transmembrane transporter activity
ACHL_RS04165	COG1136	(ABC) transporter
ACHL_RS04175	COG1966	Carbon starvation protein
ACHL_RS04195	COG0656	L-ascorbic acid biosynthetic process
ACHL_RS04215	COG1252	NADH dehydrogenase
ACHL_RS04235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACHL_RS04240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACHL_RS04260	COG0588	phosphoglycerate mutase activity
ACHL_RS04270	COG5002	protein histidine kinase activity
ACHL_RS04290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACHL_RS04295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACHL_RS04300	COG0215	cysteine-tRNA ligase activity
ACHL_RS04330	COG0366	Alpha amylase catalytic
ACHL_RS04340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACHL_RS04365	COG0277	FAD linked oxidase domain protein
ACHL_RS04375	COG3842	ATPase activity
ACHL_RS04435	COG0783	Belongs to the Dps family
ACHL_RS04440	COG0477	Major facilitator Superfamily
ACHL_RS04450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACHL_RS04450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACHL_RS04455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACHL_RS04465	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ACHL_RS04490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACHL_RS04505	COG1278	Cold shock
ACHL_RS04515	COG0459	protein refolding
ACHL_RS04520	COG1653	transport
ACHL_RS04525	COG0328	RNA-DNA hybrid ribonuclease activity
ACHL_RS04535	COG2205	protein histidine kinase activity
ACHL_RS04540	COG0745	RESPONSE REGULATOR receiver
ACHL_RS04545	COG0726	polysaccharide deacetylase
ACHL_RS04570	COG1061	Type III restriction enzyme res subunit
ACHL_RS04585	COG1278	Cold shock
ACHL_RS04605	COG0739	heme binding
ACHL_RS04610	COG0791	NLP P60 protein
ACHL_RS04610	COG1388	LysM domain
ACHL_RS04610	COG3103	Sh3 type 3 domain protein
ACHL_RS04625	COG0746	molybdenum cofactor guanylyltransferase activity
ACHL_RS04640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACHL_RS04665	COG1132	(ABC) transporter
ACHL_RS04670	COG0494	nUDIX hydrolase
ACHL_RS04695	COG0483	inositol monophosphate 1-phosphatase activity
ACHL_RS04710	COG0045	succinate-CoA ligase (ADP-forming) activity
ACHL_RS04725	COG0640	Transcriptional regulator
ACHL_RS04730	COG1942	4-Oxalocrotonate Tautomerase
ACHL_RS04745	COG3962	Belongs to the TPP enzyme family
ACHL_RS04760	COG0673	inositol 2-dehydrogenase activity
ACHL_RS04765	COG1082	Xylose isomerase domain protein TIM barrel
ACHL_RS04770	COG2814	Major facilitator Superfamily
ACHL_RS04775	COG1846	Transcriptional regulator
ACHL_RS04780	COG2814	Major facilitator Superfamily
ACHL_RS04815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACHL_RS04820	COG1609	Transcriptional regulator
ACHL_RS04825	COG3718	enzyme involved in inositol metabolism
ACHL_RS04830	COG2188	Transcriptional regulator
ACHL_RS04835	COG2814	Major facilitator Superfamily
ACHL_RS04860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACHL_RS04865	COG1396	sequence-specific DNA binding
ACHL_RS04880	COG0028	Belongs to the TPP enzyme family
ACHL_RS04890	COG0477	Major facilitator Superfamily
ACHL_RS04915	COG1401	restriction endodeoxyribonuclease activity
ACHL_RS04925	COG5002	protein histidine kinase activity
ACHL_RS04930	COG0745	RESPONSE REGULATOR receiver
ACHL_RS04940	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACHL_RS04940	COG4124	Belongs to the glycosyl hydrolase 26 family
ACHL_RS04960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACHL_RS04980	COG1902	pentaerythritol trinitrate reductase activity
ACHL_RS05005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACHL_RS05020	COG3583	domain protein
ACHL_RS05025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACHL_RS05035	COG1254	Belongs to the acylphosphatase family
ACHL_RS05050	COG0477	Major facilitator Superfamily
ACHL_RS05055	COG1063	alcohol dehydrogenase
ACHL_RS05070	COG0246	Mannitol dehydrogenase
ACHL_RS05075	COG0800	Aldolase
ACHL_RS05100	COG0667	Aldo Keto reductase
ACHL_RS05105	COG1063	alcohol dehydrogenase
ACHL_RS05115	COG0477	Major facilitator Superfamily
ACHL_RS05120	COG0412	Dienelactone hydrolase
ACHL_RS05125	COG0366	Alpha amylase catalytic
ACHL_RS05130	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACHL_RS05135	COG0640	Transcriptional regulator
ACHL_RS05170	COG1082	Xylose isomerase domain protein TIM barrel
ACHL_RS05190	COG2814	Major facilitator Superfamily
ACHL_RS05195	COG1846	Transcriptional regulator
ACHL_RS05215	COG3655	Transcriptional regulator
ACHL_RS05225	COG0346	lactoylglutathione lyase activity
ACHL_RS05270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACHL_RS05270	COG2190	(PTS) system
ACHL_RS05270	COG1263	PTS System
ACHL_RS05275	COG2723	6-phospho-beta-galactosidase activity
ACHL_RS05280	COG3711	transcriptional antiterminator
ACHL_RS05285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACHL_RS05295	COG0277	FAD linked oxidase domain protein
ACHL_RS05300	COG3619	membrane
ACHL_RS05355	COG0402	S-adenosylhomocysteine deaminase activity
ACHL_RS05375	COG0477	Major facilitator Superfamily
ACHL_RS05385	COG2130	NADP-dependent
ACHL_RS05400	COG2267	carboxylic ester hydrolase activity
ACHL_RS05420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACHL_RS05425	COG1113	amino acid transport
ACHL_RS05435	COG3549	Plasmid maintenance system killer
ACHL_RS05495	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACHL_RS05510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ACHL_RS05530	COG1349	DNA-binding transcription factor activity
ACHL_RS05535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACHL_RS05545	COG0601	transmembrane transport
ACHL_RS05550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACHL_RS05555	COG4172	Belongs to the ABC transporter superfamily
ACHL_RS05560	COG4608	Belongs to the ABC transporter superfamily
ACHL_RS05565	COG0667	Aldo Keto reductase
ACHL_RS05570	COG3836	Belongs to the HpcH HpaI aldolase family
ACHL_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS05585	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACHL_RS05615	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS05625	COG0765	amino acid transport
ACHL_RS05635	COG0154	amidase activity
ACHL_RS05640	COG1802	Transcriptional regulator
ACHL_RS05650	COG3540	Alkaline phosphatase
ACHL_RS05655	COG3708	Transcriptional regulator
ACHL_RS05655	COG2207	Transcriptional regulator
ACHL_RS05675	COG1278	Cold shock
ACHL_RS05700	COG3265	gluconokinase activity
ACHL_RS05705	COG2610	gluconate transmembrane transporter activity
ACHL_RS05720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACHL_RS05745	COG0833	amino acid
ACHL_RS05755	COG1414	Transcriptional regulator
ACHL_RS05760	COG2040	homocysteine
ACHL_RS05765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACHL_RS05775	COG5001	Diguanylate cyclase
ACHL_RS05775	COG3300	MHYT domain
ACHL_RS05780	COG2261	transglycosylase associated protein
ACHL_RS05785	COG0561	phosphatase activity
ACHL_RS05830	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS05830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACHL_RS05860	COG0477	Major facilitator Superfamily
ACHL_RS05865	COG0138	bifunctional purine biosynthesis protein purh
ACHL_RS05875	COG2838	Isocitrate dehydrogenase
ACHL_RS05885	COG0515	serine threonine protein kinase
ACHL_RS05900	COG0673	inositol 2-dehydrogenase activity
ACHL_RS05905	COG1136	(ABC) transporter
ACHL_RS05920	COG4213	ABC transporter substrate-binding protein
ACHL_RS05950	COG0531	amino acid
ACHL_RS05970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACHL_RS05975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACHL_RS06000	COG0708	Exodeoxyribonuclease III
ACHL_RS06005	COG0180	Tryptophanyl-tRNA synthetase
ACHL_RS06030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACHL_RS06045	COG2009	succinate dehydrogenase
ACHL_RS06055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACHL_RS06055	COG1473	amidohydrolase
ACHL_RS06060	COG1846	Transcriptional regulator
ACHL_RS06065	COG1764	response to oxidative stress
ACHL_RS06070	COG2130	NADP-dependent
ACHL_RS06075	COG1744	ABC transporter substrate-binding protein PnrA-like
ACHL_RS06080	COG3845	ABC transporter
ACHL_RS06085	COG4603	Belongs to the binding-protein-dependent transport system permease family
ACHL_RS06090	COG1079	Belongs to the binding-protein-dependent transport system permease family
ACHL_RS06105	COG0586	Pfam SNARE associated Golgi protein
ACHL_RS06115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACHL_RS06120	COG3956	TIGRFAM MazG family protein
ACHL_RS06125	COG0148	phosphopyruvate hydratase activity
ACHL_RS06150	COG1252	NADH dehydrogenase
ACHL_RS06185	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACHL_RS06195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACHL_RS06205	COG2017	converts alpha-aldose to the beta-anomer
ACHL_RS06215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACHL_RS06225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACHL_RS06235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACHL_RS06250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACHL_RS06255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACHL_RS06290	COG0114	fumarate hydratase activity
ACHL_RS06295	COG0288	reversible hydration of carbon dioxide
ACHL_RS06305	COG1494	fructose-1,6-bisphosphatase
ACHL_RS06315	COG1482	cell wall glycoprotein biosynthetic process
ACHL_RS06320	COG1316	TRANSCRIPTIONal
ACHL_RS06375	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACHL_RS06380	COG1376	ErfK ybiS ycfS ynhG family protein
ACHL_RS06430	COG0714	Associated with various cellular activities
ACHL_RS06435	COG0084	hydrolase, TatD family'
ACHL_RS06440	COG3583	domain protein
ACHL_RS06445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACHL_RS06450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACHL_RS06455	COG0488	(ABC) transporter
ACHL_RS06470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACHL_RS06475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACHL_RS06480	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACHL_RS06485	COG0193	aminoacyl-tRNA hydrolase activity
ACHL_RS06505	COG0822	iron-sulfur transferase activity
ACHL_RS06520	COG0702	epimerase
ACHL_RS06540	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACHL_RS06545	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACHL_RS06565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACHL_RS06575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACHL_RS06600	COG0243	molybdopterin cofactor binding
ACHL_RS06605	COG2223	nitrite transmembrane transporter activity
ACHL_RS06610	COG0477	Major facilitator Superfamily
ACHL_RS06630	COG0424	maF-like protein
ACHL_RS06635	COG2409	Drug exporters of the RND superfamily
ACHL_RS06650	COG1823	symporter activity
ACHL_RS06665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACHL_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS06700	COG0714	Associated with various cellular activities
ACHL_RS06720	COG0631	protein serine/threonine phosphatase activity
ACHL_RS06740	COG1674	ftsk spoiiie
ACHL_RS06750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACHL_RS06755	COG0483	inositol monophosphate 1-phosphatase activity
ACHL_RS06765	COG0251	oxidation-reduction process
ACHL_RS06770	COG4565	transcriptional regulatory protein
ACHL_RS06775	COG3290	protein histidine kinase activity
ACHL_RS06780	COG2851	Citrate transporter
ACHL_RS06785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACHL_RS06790	COG0154	amidase activity
ACHL_RS06795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACHL_RS06800	COG0583	DNA-binding transcription factor activity
ACHL_RS06805	COG1063	alcohol dehydrogenase
ACHL_RS06810	COG0156	8-amino-7-oxononanoate synthase activity
ACHL_RS06820	COG1228	amidohydrolase
ACHL_RS06825	COG1349	DNA-binding transcription factor activity
ACHL_RS06840	COG2873	o-acetylhomoserine
ACHL_RS06845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACHL_RS06855	COG0400	carboxylic ester hydrolase activity
ACHL_RS06870	COG0423	glycine-tRNA ligase activity
ACHL_RS06905	COG0358	DNA primase activity
ACHL_RS06925	COG2814	Major facilitator Superfamily
ACHL_RS06945	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS06965	COG0052	Belongs to the universal ribosomal protein uS2 family
ACHL_RS06970	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACHL_RS06975	COG0528	UMP kinase activity
ACHL_RS06980	COG0233	cytoplasmic translational termination
ACHL_RS07000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACHL_RS07010	COG3279	Response regulator of the LytR AlgR family
ACHL_RS07015	COG3275	phosphorelay sensor kinase activity
ACHL_RS07025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACHL_RS07035	COG1522	sequence-specific DNA binding
ACHL_RS07045	COG0022	dehydrogenase e1 component
ACHL_RS07050	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACHL_RS07060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACHL_RS07070	COG1960	acyl-CoA dehydrogenase activity
ACHL_RS07100	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACHL_RS07105	COG0750	zinc metalloprotease
ACHL_RS07125	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACHL_RS07140	COG0442	prolyl-tRNA aminoacylation
ACHL_RS07165	COG0779	Required for maturation of 30S ribosomal subunits
ACHL_RS07180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACHL_RS07185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACHL_RS07195	COG0590	tRNA wobble adenosine to inosine editing
ACHL_RS07200	COG3118	belongs to the thioredoxin family
ACHL_RS07205	COG0436	Aminotransferase
ACHL_RS07210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACHL_RS07225	COG0196	riboflavin kinase activity
ACHL_RS07230	COG3483	tryptophan 2,3-dioxygenase activity
ACHL_RS07240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACHL_RS07245	COG1185	polyribonucleotide nucleotidyltransferase activity
ACHL_RS07250	COG0612	Peptidase, M16
ACHL_RS07290	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACHL_RS07300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACHL_RS07325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACHL_RS07330	COG1674	ftsk spoiiie
ACHL_RS07340	COG1546	Belongs to the CinA family
ACHL_RS07340	COG1058	Belongs to the CinA family
ACHL_RS07345	COG1396	sequence-specific DNA binding
ACHL_RS07360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACHL_RS07370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACHL_RS07375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACHL_RS07380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACHL_RS07385	COG2813	Specifically methylates the guanine in position
ACHL_RS07390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACHL_RS07400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACHL_RS07405	COG1388	LysM domain
ACHL_RS07410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACHL_RS07415	COG0131	Imidazoleglycerol-phosphate dehydratase
ACHL_RS07420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACHL_RS07425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACHL_RS07445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACHL_RS07450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACHL_RS07455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACHL_RS07460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACHL_RS07465	COG2261	transglycosylase associated protein
ACHL_RS07475	COG2814	Major facilitator Superfamily
ACHL_RS07480	COG0494	nUDIX hydrolase
ACHL_RS07500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACHL_RS07505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACHL_RS07505	COG0072	phenylalanine-tRNA ligase activity
ACHL_RS07530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACHL_RS07535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACHL_RS07540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACHL_RS07545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACHL_RS07550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACHL_RS07555	COG1438	arginine binding
ACHL_RS07560	COG0137	argininosuccinate synthase activity
ACHL_RS07565	COG0165	Argininosuccinate lyase
ACHL_RS07580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACHL_RS07580	COG2169	Transcriptional regulator
ACHL_RS07590	COG2094	Belongs to the DNA glycosylase MPG family
ACHL_RS07595	COG3973	AAA domain
ACHL_RS07600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACHL_RS07625	COG0647	UMP catabolic process
ACHL_RS07640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACHL_RS07645	COG0497	DNA recombination
ACHL_RS07650	COG0504	CTP synthase activity
ACHL_RS07655	COG0494	nUDIX hydrolase
ACHL_RS07680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACHL_RS07685	COG2079	MmgE PrpD family protein
ACHL_RS07705	COG3290	protein histidine kinase activity
ACHL_RS07710	COG1301	dicarboxylic acid transport
ACHL_RS07720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACHL_RS07725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACHL_RS07740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACHL_RS07750	COG1160	GTP binding
ACHL_RS07765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACHL_RS07770	COG0509	glycine decarboxylation via glycine cleavage system
ACHL_RS07805	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACHL_RS07815	COG1940	carbohydrate kinase activity
ACHL_RS07840	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ACHL_RS07845	COG2815	serine threonine protein kinase
ACHL_RS07845	COG0515	serine threonine protein kinase
ACHL_RS07850	COG3942	CHAP domain
ACHL_RS07850	COG1388	LysM domain
ACHL_RS07860	COG0142	geranyltranstransferase activity
ACHL_RS07870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACHL_RS07880	COG2001	Belongs to the MraZ family
ACHL_RS07885	COG0275	rRNA processing
ACHL_RS07895	COG0768	penicillin binding
ACHL_RS07900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACHL_RS07910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACHL_RS07915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACHL_RS07920	COG0772	Belongs to the SEDS family
ACHL_RS07925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACHL_RS07930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACHL_RS07940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACHL_RS07945	COG1496	oxidoreductase activity
ACHL_RS07950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACHL_RS07955	COG1799	cell septum assembly
ACHL_RS07965	COG3599	regulation of cell shape
ACHL_RS07970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACHL_RS07980	COG0587	DNA-directed DNA polymerase activity
ACHL_RS07995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACHL_RS08000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACHL_RS08015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACHL_RS08020	COG0174	glutamine synthetase
ACHL_RS08025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACHL_RS08055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACHL_RS08060	COG0321	lipoyl(octanoyl) transferase activity
ACHL_RS08070	COG1090	epimerase
ACHL_RS08075	COG0793	Belongs to the peptidase S41A family
ACHL_RS08075	COG4946	Tricorn protease homolog
ACHL_RS08080	COG1764	response to oxidative stress
ACHL_RS08090	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACHL_RS08095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACHL_RS08100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACHL_RS08120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACHL_RS08145	COG1271	oxidase subunit
ACHL_RS08150	COG1294	oxidase, subunit
ACHL_RS08155	COG4988	ABC transporter
ACHL_RS08170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACHL_RS08175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACHL_RS08175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACHL_RS08190	COG1435	thymidine kinase activity
ACHL_RS08210	COG0756	dUTP diphosphatase activity
ACHL_RS08235	COG0569	domain protein
ACHL_RS08240	COG0531	amino acid
ACHL_RS08245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACHL_RS08255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACHL_RS08260	COG3557	Belongs to the UPF0374 family
ACHL_RS08270	COG0667	Aldo Keto reductase
ACHL_RS08295	COG1122	ATPase activity
ACHL_RS08300	COG1024	Enoyl-CoA hydratase
ACHL_RS08300	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACHL_RS08305	COG0183	Belongs to the thiolase family
ACHL_RS08310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACHL_RS08335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACHL_RS08350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACHL_RS08370	COG3135	benzoate transporter
ACHL_RS08415	COG0242	peptide deformylase activity
ACHL_RS08420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACHL_RS08430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACHL_RS08450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACHL_RS08450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACHL_RS08460	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACHL_RS08465	COG0140	phosphoribosyl-ATP diphosphatase activity
ACHL_RS08470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACHL_RS08475	COG0107	imidazoleglycerol-phosphate synthase activity
ACHL_RS08490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACHL_RS08510	COG0134	indole-3-glycerol-phosphate synthase activity
ACHL_RS08515	COG0133	tryptophan synthase activity
ACHL_RS08520	COG0159	tryptophan synthase activity
ACHL_RS08525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACHL_RS08530	COG0067	glutamate synthase
ACHL_RS08530	COG0069	glutamate synthase activity
ACHL_RS08530	COG0070	glutamate synthase
ACHL_RS08615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACHL_RS08625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACHL_RS08660	COG0395	ABC-type sugar transport system, permease component
ACHL_RS08665	COG1063	alcohol dehydrogenase
ACHL_RS08670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACHL_RS08690	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS08700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACHL_RS08705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACHL_RS08710	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACHL_RS08770	COG1063	alcohol dehydrogenase
ACHL_RS08780	COG1850	ribulose-bisphosphate carboxylase activity
ACHL_RS08815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACHL_RS08835	COG0395	ABC-type sugar transport system, permease component
ACHL_RS08850	COG1609	Transcriptional regulator
ACHL_RS08855	COG0667	Aldo Keto reductase
ACHL_RS08875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACHL_RS08875	COG2755	lipolytic protein G-D-S-L family
ACHL_RS08885	COG2268	Band 7 protein
ACHL_RS08890	COG0277	FAD linked oxidase domain protein
ACHL_RS08895	COG0475	glutathione-regulated potassium exporter activity
ACHL_RS08900	COG0586	Pfam SNARE associated Golgi protein
ACHL_RS08925	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ACHL_RS08945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACHL_RS08950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACHL_RS08955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACHL_RS08960	COG4172	Belongs to the ABC transporter superfamily
ACHL_RS08970	COG0601	transmembrane transport
ACHL_RS08975	COG0747	negative chemotaxis
ACHL_RS08980	COG0277	FAD linked oxidase domain protein
ACHL_RS08985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACHL_RS09000	COG1643	Atp-dependent helicase
ACHL_RS09015	COG0009	L-threonylcarbamoyladenylate synthase
ACHL_RS09045	COG2197	response regulator
ACHL_RS09075	COG2050	protein possibly involved in aromatic compounds catabolism
ACHL_RS09085	COG4552	Acetyltransferase involved in intracellular survival and related
ACHL_RS09090	COG0539	negative regulation of cytoplasmic translation
ACHL_RS09100	COG1739	Uncharacterized protein family UPF0029
ACHL_RS09110	COG4152	abc transporter atp-binding protein
ACHL_RS09115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACHL_RS09115	COG0237	dephospho-CoA kinase activity
ACHL_RS09120	COG0556	nucleotide-excision repair
ACHL_RS09130	COG0477	Major facilitator Superfamily
ACHL_RS09150	COG4106	trans-aconitate 2-methyltransferase activity
ACHL_RS09180	COG0204	Acyl-transferase
ACHL_RS09180	COG0318	PFAM AMP-dependent synthetase and ligase
ACHL_RS09185	COG0322	excinuclease ABC activity
ACHL_RS09190	COG1660	Displays ATPase and GTPase activities
ACHL_RS09195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACHL_RS09200	COG1481	regulation of sporulation
ACHL_RS09205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACHL_RS09210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACHL_RS09215	COG0126	phosphoglycerate kinase activity
ACHL_RS09220	COG0149	triose-phosphate isomerase activity
ACHL_RS09225	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACHL_RS09235	COG0363	glucosamine-6-phosphate deaminase activity
ACHL_RS09250	COG0166	Belongs to the GPI family
ACHL_RS09255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACHL_RS09265	COG0109	protoheme IX farnesyltransferase activity
ACHL_RS09270	COG0659	secondary active sulfate transmembrane transporter activity
ACHL_RS09275	COG1612	heme a metabolic process
ACHL_RS09285	COG1131	(ABC) transporter
ACHL_RS09310	COG0396	ATPase activity
ACHL_RS09315	COG2151	metal-sulfur cluster biosynthetic enzyme
ACHL_RS09325	COG0318	PFAM AMP-dependent synthetase and ligase
ACHL_RS09340	COG1122	ATPase activity
ACHL_RS09345	COG1268	BioY protein
ACHL_RS09350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACHL_RS09360	COG0488	(ABC) transporter
ACHL_RS09410	COG2378	regulation of single-species biofilm formation
ACHL_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS09445	COG0560	Phosphoserine phosphatase
ACHL_RS09445	COG3830	Belongs to the UPF0237 family
ACHL_RS09450	COG1119	ATPase activity
ACHL_RS09465	COG0254	rRNA binding
ACHL_RS09470	COG0095	Lipoate-protein ligase
ACHL_RS09480	COG2855	membrane
ACHL_RS09495	COG1305	Transglutaminase-like
ACHL_RS09510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACHL_RS09515	COG0297	glycogen (starch) synthase activity
ACHL_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS09555	COG0435	Glutathione S-transferase
ACHL_RS09575	COG0859	PFAM glycosyl transferase family 9
ACHL_RS09590	COG0596	Alpha beta hydrolase
ACHL_RS09625	COG0656	L-ascorbic acid biosynthetic process
ACHL_RS09630	COG1968	undecaprenyl-diphosphatase activity
ACHL_RS09635	COG0215	cysteine-tRNA ligase activity
ACHL_RS09645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACHL_RS09650	COG0517	IMP dehydrogenase activity
ACHL_RS09650	COG1994	Peptidase M50
ACHL_RS09660	COG1222	aaa ATPase
ACHL_RS09665	COG4122	O-methyltransferase activity
ACHL_RS09675	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACHL_RS09680	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACHL_RS09685	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ACHL_RS09690	COG0545	Peptidyl-prolyl cis-trans isomerase
ACHL_RS09710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACHL_RS09715	COG0805	protein transport
ACHL_RS09720	COG4581	dead DEAH box helicase
ACHL_RS09725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ACHL_RS09730	COG1216	Glycosyl transferase, family 2
ACHL_RS09755	COG0242	peptide deformylase activity
ACHL_RS09765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACHL_RS09775	COG3424	synthase
ACHL_RS09800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACHL_RS09805	COG1845	cytochrome c oxidase, subunit III
ACHL_RS09810	COG2010	Cytochrome c
ACHL_RS09815	COG0723	plastoquinol--plastocyanin reductase activity
ACHL_RS09820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ACHL_RS09840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACHL_RS09845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACHL_RS09865	COG0167	dihydroorotate dehydrogenase activity
ACHL_RS09880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACHL_RS09885	COG1381	Involved in DNA repair and RecF pathway recombination
ACHL_RS09890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACHL_RS09895	COG3590	peptidase
ACHL_RS09900	COG1316	TRANSCRIPTIONal
ACHL_RS09905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACHL_RS09915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACHL_RS09930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACHL_RS09935	COG0484	heat shock protein binding
ACHL_RS09940	COG1420	regulation of RNA biosynthetic process
ACHL_RS09960	COG0481	GTPase activity
ACHL_RS09970	COG0268	Binds directly to 16S ribosomal RNA
ACHL_RS09990	COG1307	EDD domain protein, DegV family
ACHL_RS09995	COG0495	leucyl-tRNA aminoacylation
ACHL_RS10000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACHL_RS10005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACHL_RS10010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACHL_RS10015	COG2390	Transcriptional regulator
ACHL_RS10020	COG0656	L-ascorbic acid biosynthetic process
ACHL_RS10030	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS10040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACHL_RS10050	COG1758	RNA polymerase activity
ACHL_RS10055	COG0194	GDP metabolic process
ACHL_RS10060	COG0194	GDP metabolic process
ACHL_RS10065	COG0284	orotidine-5'-phosphate decarboxylase activity
ACHL_RS10070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACHL_RS10075	COG0505	Belongs to the CarA family
ACHL_RS10085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACHL_RS10090	COG0540	Belongs to the ATCase OTCase family
ACHL_RS10095	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACHL_RS10105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACHL_RS10110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACHL_RS10120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACHL_RS10125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACHL_RS10130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACHL_RS10135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACHL_RS10150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACHL_RS10165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACHL_RS10185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACHL_RS10190	COG0124	histidyl-tRNA synthetase
ACHL_RS10195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACHL_RS10200	COG1196	nuclear chromosome segregation
ACHL_RS10205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACHL_RS10210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACHL_RS10215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACHL_RS10225	COG2255	four-way junction helicase activity
ACHL_RS10230	COG0632	four-way junction helicase activity
ACHL_RS10235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACHL_RS10240	COG0217	transcriptional regulatory protein
ACHL_RS10245	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ACHL_RS10270	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACHL_RS10275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACHL_RS10285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACHL_RS10290	COG0587	DNA-directed DNA polymerase activity
ACHL_RS10305	COG1605	Chorismate mutase
ACHL_RS10305	COG0077	Prephenate dehydratase
ACHL_RS10315	COG2135	peptidase activity
ACHL_RS10330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACHL_RS10335	COG1695	Transcriptional regulator
ACHL_RS10365	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS10400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACHL_RS10405	COG1234	tRNA 3'-trailer cleavage
ACHL_RS10420	COG0589	response to stress
ACHL_RS10460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACHL_RS10475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACHL_RS10475	COG0574	Belongs to the PEP-utilizing enzyme family
ACHL_RS10530	COG2268	Band 7 protein
ACHL_RS10550	COG1175	transmembrane transport
ACHL_RS10555	COG0395	ABC-type sugar transport system, permease component
ACHL_RS10560	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS10570	COG3321	synthase
ACHL_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS10570	COG0604	alcohol dehydrogenase
ACHL_RS10575	COG0768	penicillin binding
ACHL_RS10605	COG1842	Phage shock protein A
ACHL_RS10615	COG2826	transposase and inactivated derivatives, IS30 family
ACHL_RS10625	COG0477	Major facilitator Superfamily
ACHL_RS10655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACHL_RS10660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACHL_RS10665	COG1780	Probably involved in ribonucleotide reductase function
ACHL_RS10675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACHL_RS10690	COG0583	DNA-binding transcription factor activity
ACHL_RS10700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACHL_RS10730	COG0714	Associated with various cellular activities
ACHL_RS10745	COG2813	Specifically methylates the guanine in position
ACHL_RS10750	COG0492	ferredoxin-NADP+ reductase activity
ACHL_RS10755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACHL_RS10770	COG0799	negative regulation of ribosome biogenesis
ACHL_RS10780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACHL_RS10790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACHL_RS10795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACHL_RS10800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACHL_RS10805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACHL_RS10810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACHL_RS10815	COG0351	phosphomethylpyrimidine kinase
ACHL_RS10815	COG0352	thiamine-phosphate diphosphorylase activity
ACHL_RS10815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACHL_RS10820	COG1530	ribonuclease E activity
ACHL_RS10830	COG0105	UTP biosynthetic process
ACHL_RS10840	COG0285	dihydrofolate synthase activity
ACHL_RS10845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACHL_RS10860	COG0525	valine-tRNA ligase activity
ACHL_RS10865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACHL_RS10870	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACHL_RS10875	COG0740	serine-type endopeptidase activity
ACHL_RS10880	COG0740	serine-type endopeptidase activity
ACHL_RS10885	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACHL_RS10930	COG0668	transmembrane transport
ACHL_RS10945	COG1946	Acyl-CoA thioesterase
ACHL_RS10970	COG1940	carbohydrate kinase activity
ACHL_RS10975	COG2115	Belongs to the xylose isomerase family
ACHL_RS10980	COG1070	Carbohydrate kinase
ACHL_RS10995	COG0673	inositol 2-dehydrogenase activity
ACHL_RS11000	COG1609	Transcriptional regulator
ACHL_RS11005	COG2755	lipolytic protein G-D-S-L family
ACHL_RS11005	COG0657	acetylesterase activity
ACHL_RS11010	COG2017	converts alpha-aldose to the beta-anomer
ACHL_RS11060	COG3022	response to hydroperoxide
ACHL_RS11070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACHL_RS11075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACHL_RS11085	COG1045	serine acetyltransferase
ACHL_RS11090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACHL_RS11125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACHL_RS11140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACHL_RS11145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACHL_RS11150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACHL_RS11160	COG4974	Belongs to the 'phage' integrase family
ACHL_RS11175	COG0792	nuclease activity
ACHL_RS11185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACHL_RS11195	COG0681	Belongs to the peptidase S26 family
ACHL_RS11200	COG0335	large ribosomal subunit rRNA binding
ACHL_RS11205	COG0336	Belongs to the RNA methyltransferase TrmD family
ACHL_RS11210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACHL_RS11215	COG1837	Belongs to the UPF0109 family
ACHL_RS11220	COG0228	four-way junction DNA binding
ACHL_RS11230	COG2514	catechol 2,3-dioxygenase activity
ACHL_RS11255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACHL_RS11270	COG2814	Major facilitator Superfamily
ACHL_RS11295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACHL_RS11300	COG0571	ribonuclease III activity
ACHL_RS11305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACHL_RS11320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACHL_RS11335	COG0742	ribosomal rna small subunit methyltransferase
ACHL_RS11340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACHL_RS11360	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACHL_RS11365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACHL_RS11375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACHL_RS11380	COG0066	3-isopropylmalate dehydratase activity
ACHL_RS11385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACHL_RS11390	COG1414	Transcriptional regulator
ACHL_RS11430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACHL_RS11435	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS11440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACHL_RS11450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACHL_RS11455	COG0473	3-isopropylmalate dehydrogenase activity
ACHL_RS11460	COG4585	Histidine kinase
ACHL_RS11465	COG2197	response regulator
ACHL_RS11470	COG0577	efflux transmembrane transporter activity
ACHL_RS11470	COG1136	(ABC) transporter
ACHL_RS11485	COG0577	efflux transmembrane transporter activity
ACHL_RS11485	COG1136	(ABC) transporter
ACHL_RS11495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACHL_RS11500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACHL_RS11505	COG0440	acetolactate synthase activity
ACHL_RS11515	COG0129	dihydroxy-acid dehydratase activity
ACHL_RS11550	COG0747	negative chemotaxis
ACHL_RS11555	COG0579	oxidoreductase
ACHL_RS11560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACHL_RS11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS11575	COG1305	Transglutaminase-like
ACHL_RS11595	COG1104	cysteine desulfurase activity
ACHL_RS11605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACHL_RS11610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACHL_RS11620	COG1113	amino acid transport
ACHL_RS11625	COG2267	carboxylic ester hydrolase activity
ACHL_RS11650	COG0419	ATPase involved in DNA repair
ACHL_RS11655	COG0420	3'-5' exonuclease activity
ACHL_RS11680	COG0586	Pfam SNARE associated Golgi protein
ACHL_RS11685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACHL_RS11690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACHL_RS11695	COG1234	tRNA 3'-trailer cleavage
ACHL_RS11700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACHL_RS11710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACHL_RS11720	COG1335	isochorismatase
ACHL_RS11735	COG0363	glucosamine-6-phosphate deaminase activity
ACHL_RS11755	COG1902	pentaerythritol trinitrate reductase activity
ACHL_RS11785	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ACHL_RS11795	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACHL_RS11800	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACHL_RS11810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACHL_RS11815	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACHL_RS11820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACHL_RS11825	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACHL_RS11830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACHL_RS11835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACHL_RS11840	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACHL_RS11845	COG0356	it plays a direct role in the translocation of protons across the membrane
ACHL_RS11880	COG2890	protein-(glutamine-N5) methyltransferase activity
ACHL_RS11885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACHL_RS11895	COG0083	homoserine kinase activity
ACHL_RS11900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACHL_RS11905	COG0460	homoserine dehydrogenase
ACHL_RS11910	COG0019	diaminopimelate decarboxylase activity
ACHL_RS11915	COG0018	arginyl-trna synthetase
ACHL_RS11955	COG1643	Atp-dependent helicase
ACHL_RS11960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACHL_RS11970	COG1064	alcohol dehydrogenase
ACHL_RS12000	COG1121	(ABC) transporter
ACHL_RS12020	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACHL_RS12020	COG0567	Dehydrogenase, E1 component
ACHL_RS12045	COG1595	DNA-templated transcription, initiation
ACHL_RS12055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACHL_RS12065	COG0483	inositol monophosphate 1-phosphatase activity
ACHL_RS12070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACHL_RS12085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACHL_RS12090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACHL_RS12100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACHL_RS12105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACHL_RS12105	COG2755	lipolytic protein G-D-S-L family
ACHL_RS12110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACHL_RS12125	COG2884	Cell division ATP-binding protein ftsE
ACHL_RS12130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACHL_RS12175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACHL_RS12180	COG1088	dTDP-glucose 4,6-dehydratase activity
ACHL_RS12190	COG0463	Glycosyl transferase, family 2
ACHL_RS12240	COG1216	Glycosyl transferase, family 2
ACHL_RS12275	COG2902	Dehydrogenase
ACHL_RS12310	COG0653	protein targeting
ACHL_RS12315	COG3214	Protein conserved in bacteria
ACHL_RS12320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACHL_RS12325	COG1040	competence protein
ACHL_RS12330	COG5401	PFAM Sporulation and spore germination
ACHL_RS12335	COG5002	protein histidine kinase activity
ACHL_RS12360	COG0714	Associated with various cellular activities
ACHL_RS12395	COG0601	transmembrane transport
ACHL_RS12405	COG0482	sulfurtransferase activity
ACHL_RS12425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACHL_RS12430	COG1595	DNA-templated transcription, initiation
ACHL_RS12440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACHL_RS12445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACHL_RS12455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACHL_RS12465	COG1842	Phage shock protein A
ACHL_RS12470	COG0415	Belongs to the DNA photolyase family
ACHL_RS12490	COG1615	UPF0182 protein
ACHL_RS12515	COG2816	NAD+ diphosphatase activity
ACHL_RS12545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACHL_RS12550	COG0765	amino acid transport
ACHL_RS12555	COG1126	abc transporter atp-binding protein
ACHL_RS12560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACHL_RS12570	COG0113	porphobilinogen synthase activity
ACHL_RS12580	COG0181	hydroxymethylbilane synthase activity
ACHL_RS12585	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACHL_RS12590	COG3253	May function as heme-dependent peroxidase
ACHL_RS12600	COG1231	oxidoreductase activity
ACHL_RS12605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACHL_RS12610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACHL_RS12635	COG2022	thiamine diphosphate biosynthetic process
ACHL_RS12650	COG0352	thiamine-phosphate diphosphorylase activity
ACHL_RS12655	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ACHL_RS12660	COG0513	Belongs to the DEAD box helicase family
ACHL_RS12665	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ACHL_RS12675	COG0006	proline dipeptidase activity
ACHL_RS12685	COG2239	Acts as a magnesium transporter
ACHL_RS12700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACHL_RS12710	COG1595	DNA-templated transcription, initiation
ACHL_RS12735	COG1126	abc transporter atp-binding protein
ACHL_RS12740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACHL_RS12745	COG0765	amino acid transport
ACHL_RS12750	COG0765	amino acid transport
ACHL_RS12755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACHL_RS12760	COG2171	N-acyltransferase activity
ACHL_RS12775	COG3226	Transcriptional regulator
ACHL_RS12780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACHL_RS12805	COG1217	gtp-binding protein TYPA
ACHL_RS12820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACHL_RS12840	COG3046	protein related to deoxyribodipyrimidine photolyase
ACHL_RS12850	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS12860	COG0012	GTP binding
ACHL_RS12865	COG1322	Protein conserved in bacteria
ACHL_RS12870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACHL_RS12880	COG1570	exodeoxyribonuclease VII activity
ACHL_RS12885	COG1722	exodeoxyribonuclease VII activity
ACHL_RS12890	COG2326	polyphosphate kinase activity
ACHL_RS12905	COG1174	glycine betaine transport
ACHL_RS12910	COG1174	glycine betaine transport
ACHL_RS12925	COG2971	BadF BadG BcrA BcrD
ACHL_RS12930	COG0583	DNA-binding transcription factor activity
ACHL_RS12935	COG2814	Major facilitator Superfamily
ACHL_RS12955	COG0598	Magnesium transport protein CorA
ACHL_RS12970	COG3201	nicotinamide mononucleotide transporter
ACHL_RS12990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACHL_RS12995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACHL_RS13015	COG0519	Catalyzes the synthesis of GMP from XMP
ACHL_RS13015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACHL_RS13035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACHL_RS13040	COG0516	GMP reductase activity
ACHL_RS13065	COG1132	(ABC) transporter
ACHL_RS13075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACHL_RS13075	COG2755	lipolytic protein G-D-S-L family
ACHL_RS13080	COG2755	lipolytic protein G-D-S-L family
ACHL_RS13080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACHL_RS13085	COG2072	flavoprotein involved in K transport
ACHL_RS13090	COG2197	response regulator
ACHL_RS13095	COG1793	dna ligase
ACHL_RS13105	COG0459	protein refolding
ACHL_RS13110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACHL_RS13115	COG0697	spore germination
ACHL_RS13130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACHL_RS13135	COG1472	Belongs to the glycosyl hydrolase 3 family
ACHL_RS13145	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACHL_RS13150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACHL_RS13165	COG0802	atpase or kinase
ACHL_RS13170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACHL_RS13175	COG1105	Belongs to the carbohydrate kinase PfkB family
ACHL_RS13180	COG1486	melibiose metabolic process
ACHL_RS13185	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS13190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACHL_RS13215	COG0667	Aldo Keto reductase
ACHL_RS13240	COG0736	holo-[acyl-carrier-protein] synthase activity
ACHL_RS13250	COG1072	(Pantothenic acid kinase))
ACHL_RS13255	COG1876	peptidase activity
ACHL_RS13260	COG1970	mechanosensitive ion channel activity
ACHL_RS13265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACHL_RS13280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACHL_RS13285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACHL_RS13290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACHL_RS13295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACHL_RS13330	COG2894	cell division
ACHL_RS13375	COG2894	cell division
ACHL_RS13405	COG0101	tRNA pseudouridine synthase activity
ACHL_RS13410	COG0203	ribosomal protein L17
ACHL_RS13415	COG0202	RNA polymerase activity
ACHL_RS13420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACHL_RS13425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACHL_RS13430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACHL_RS13435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACHL_RS13440	COG3191	aminopeptidase activity
ACHL_RS13445	COG1175	transmembrane transport
ACHL_RS13465	COG3655	Transcriptional regulator
ACHL_RS13475	COG0563	adenylate kinase activity
ACHL_RS13485	COG0200	Binds to the 23S rRNA
ACHL_RS13490	COG1841	ribosomal large subunit assembly
ACHL_RS13495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACHL_RS13500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACHL_RS13505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACHL_RS13510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACHL_RS13515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACHL_RS13520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACHL_RS13525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACHL_RS13530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACHL_RS13535	COG0255	Belongs to the universal ribosomal protein uL29 family
ACHL_RS13540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACHL_RS13545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACHL_RS13550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACHL_RS13555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACHL_RS13560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACHL_RS13565	COG0089	rRNA binding
ACHL_RS13570	COG0088	Forms part of the polypeptide exit tunnel
ACHL_RS13575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACHL_RS13580	COG0051	transcription antitermination factor activity, RNA binding
ACHL_RS13585	COG2723	6-phospho-beta-galactosidase activity
ACHL_RS13595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACHL_RS13600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACHL_RS13605	COG0049	tRNA binding
ACHL_RS13610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACHL_RS13615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACHL_RS13620	COG0085	RNA polymerase activity
ACHL_RS13630	COG0183	Belongs to the thiolase family
ACHL_RS13635	COG0442	prolyl-tRNA aminoacylation
ACHL_RS13640	COG0222	ribosome binding
ACHL_RS13645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACHL_RS13660	COG0081	regulation of translation
ACHL_RS13665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACHL_RS13685	COG0436	Aminotransferase
ACHL_RS13690	COG2197	response regulator
ACHL_RS13745	COG3485	protocatechuate 3,4-dioxygenase
ACHL_RS13755	COG0745	RESPONSE REGULATOR receiver
ACHL_RS13760	COG0456	acetyltransferase
ACHL_RS13765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACHL_RS13770	COG0494	nUDIX hydrolase
ACHL_RS13770	COG0406	alpha-ribazole phosphatase activity
ACHL_RS13785	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACHL_RS13790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACHL_RS13800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACHL_RS13815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACHL_RS13820	COG0738	Major facilitator superfamily
ACHL_RS13830	COG2030	dehydratase
ACHL_RS13860	COG4989	oxidoreductase activity
ACHL_RS13865	COG0366	Alpha amylase catalytic
ACHL_RS13875	COG0702	epimerase
ACHL_RS13885	COG0706	membrane insertase activity
ACHL_RS13915	COG0754	glutathionylspermidine amidase activity
ACHL_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS13955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACHL_RS13980	COG0318	PFAM AMP-dependent synthetase and ligase
ACHL_RS13990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACHL_RS13995	COG1131	(ABC) transporter
ACHL_RS14010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACHL_RS14035	COG1666	GTP binding
ACHL_RS14040	COG0501	Belongs to the peptidase M48B family
ACHL_RS14045	COG2814	Major facilitator Superfamily
ACHL_RS14070	COG0531	amino acid
ACHL_RS14125	COG1215	transferase activity, transferring glycosyl groups
ACHL_RS14140	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS14145	COG3835	regulator
ACHL_RS14170	COG2186	Transcriptional regulator
ACHL_RS14210	COG1648	precorrin-2 dehydrogenase activity
ACHL_RS14210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACHL_RS14225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACHL_RS14235	COG2895	sulfate adenylyltransferase (ATP) activity
ACHL_RS14245	COG0175	sulfate reduction
ACHL_RS14250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACHL_RS14260	COG2860	membrane
ACHL_RS14275	COG0142	geranyltranstransferase activity
ACHL_RS14285	COG2226	methyltransferase
ACHL_RS14290	COG1169	isochorismate synthase
ACHL_RS14300	COG0765	amino acid transport
ACHL_RS14320	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ACHL_RS14330	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS14335	COG0598	Magnesium transport protein CorA
ACHL_RS14390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACHL_RS14420	COG0596	Alpha beta hydrolase
ACHL_RS14440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACHL_RS14445	COG1121	(ABC) transporter
ACHL_RS14450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACHL_RS14465	COG2132	Multicopper oxidase
ACHL_RS14490	COG5002	protein histidine kinase activity
ACHL_RS14545	COG2353	YceI-like domain
ACHL_RS14550	COG2755	lipolytic protein G-D-S-L family
ACHL_RS14550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACHL_RS14580	COG1131	(ABC) transporter
ACHL_RS14595	COG1597	lipid kinase activity
ACHL_RS14620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACHL_RS14625	COG1621	beta-fructofuranosidase activity
ACHL_RS14630	COG1609	Transcriptional regulator
ACHL_RS14635	COG0395	ABC-type sugar transport system, permease component
ACHL_RS14655	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACHL_RS14660	COG0022	dehydrogenase e1 component
ACHL_RS14670	COG0745	RESPONSE REGULATOR receiver
ACHL_RS14675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACHL_RS14685	COG0297	glycogen (starch) synthase activity
ACHL_RS14685	COG0438	transferase activity, transferring glycosyl groups
ACHL_RS14695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACHL_RS14760	COG0745	RESPONSE REGULATOR receiver
ACHL_RS14785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACHL_RS14810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACHL_RS14830	COG0489	protein tyrosine kinase activity
ACHL_RS14845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACHL_RS14855	COG0489	protein tyrosine kinase activity
ACHL_RS14860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACHL_RS14860	COG4124	Belongs to the glycosyl hydrolase 26 family
ACHL_RS14870	COG1024	Enoyl-CoA hydratase
ACHL_RS14875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACHL_RS14880	COG2151	metal-sulfur cluster biosynthetic enzyme
ACHL_RS14885	COG3396	Phenylacetate-CoA oxygenase
ACHL_RS14890	COG3460	Phenylacetate-CoA oxygenase
ACHL_RS14895	COG3396	Phenylacetate-CoA oxygenase
ACHL_RS14925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACHL_RS14935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACHL_RS14940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACHL_RS14945	COG1684	flagellar biosynthetic protein fliR
ACHL_RS14950	COG1987	bacterial-type flagellum assembly
ACHL_RS14955	COG1338	Plays a role in the flagellum-specific transport system
ACHL_RS14975	COG1360	Flagellar Motor Protein
ACHL_RS14980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACHL_RS15005	COG0791	NLP P60 protein
ACHL_RS15015	COG1157	protein secretion by the type III secretion system
ACHL_RS15025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACHL_RS15035	COG1677	Flagellar hook-basal body complex protein FliE
ACHL_RS15045	COG1815	bacterial-type flagellum-dependent cell motility
ACHL_RS15060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACHL_RS15075	COG4786	Flagellar basal body rod
ACHL_RS15075	COG1256	bacterial-type flagellum assembly
ACHL_RS15080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACHL_RS15100	COG1120	ATPase activity
ACHL_RS15125	COG0300	oxidoreductase activity
ACHL_RS15130	COG0390	transport system, permease component
ACHL_RS15175	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACHL_RS15190	COG2059	Chromate
ACHL_RS15195	COG0492	ferredoxin-NADP+ reductase activity
ACHL_RS15210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACHL_RS15225	COG2217	Heavy metal translocating P-type atpase
ACHL_RS15240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACHL_RS15245	COG1316	TRANSCRIPTIONal
ACHL_RS15255	COG0588	phosphoglycerate mutase activity
ACHL_RS15260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACHL_RS15285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACHL_RS15290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACHL_RS15300	COG0857	belongs to the CobB CobQ family
ACHL_RS15300	COG0280	phosphate acetyltransferase
ACHL_RS15305	COG2050	protein possibly involved in aromatic compounds catabolism
ACHL_RS15340	COG2030	dehydratase
ACHL_RS15340	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS15345	COG2050	protein possibly involved in aromatic compounds catabolism
ACHL_RS15365	COG2755	lipolytic protein G-D-S-L family
ACHL_RS15380	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACHL_RS15385	COG1024	Enoyl-CoA hydratase
ACHL_RS15430	COG1266	CAAX protease self-immunity
ACHL_RS15440	COG0395	ABC-type sugar transport system, permease component
ACHL_RS15445	COG1175	transmembrane transport
ACHL_RS15460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ACHL_RS15510	COG0443	Heat shock 70 kDa protein
ACHL_RS15515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACHL_RS15525	COG0785	Cytochrome C biogenesis protein
ACHL_RS15530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACHL_RS15535	COG0406	alpha-ribazole phosphatase activity
ACHL_RS15540	COG2353	YceI-like domain
ACHL_RS15555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACHL_RS15575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACHL_RS15580	COG3458	cephalosporin-C deacetylase activity
ACHL_RS15585	COG1556	Lactate utilization protein
ACHL_RS15590	COG1139	Iron-sulfur cluster binding protein
ACHL_RS15595	COG0247	lactate metabolic process
ACHL_RS15600	COG1070	Carbohydrate kinase
ACHL_RS15605	COG3347	Dehydrogenase
ACHL_RS15605	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS15610	COG4952	isomerase
ACHL_RS15630	COG2755	lipolytic protein G-D-S-L family
ACHL_RS15635	COG0395	ABC-type sugar transport system, permease component
ACHL_RS15640	COG4209	transmembrane transport
ACHL_RS15645	COG1653	transport
ACHL_RS15650	COG5578	integral membrane protein
ACHL_RS15655	COG0673	inositol 2-dehydrogenase activity
ACHL_RS15670	COG2814	Major facilitator Superfamily
ACHL_RS15680	COG0395	ABC-type sugar transport system, permease component
ACHL_RS15685	COG1175	transmembrane transport
ACHL_RS15715	COG0395	ABC-type sugar transport system, permease component
ACHL_RS15720	COG1175	transmembrane transport
ACHL_RS15735	COG0673	inositol 2-dehydrogenase activity
ACHL_RS15750	COG4948	Mandelate Racemase Muconate Lactonizing
ACHL_RS15755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACHL_RS15765	COG0673	inositol 2-dehydrogenase activity
ACHL_RS15770	COG1609	Transcriptional regulator
ACHL_RS15780	COG0640	Transcriptional regulator
ACHL_RS15785	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACHL_RS15790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACHL_RS15795	COG0569	domain protein
ACHL_RS15800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACHL_RS15805	COG0248	Ppx GppA phosphatase
ACHL_RS15815	COG1754	DNA topoisomerase type I activity
ACHL_RS15815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACHL_RS15820	COG2890	protein-(glutamine-N5) methyltransferase activity
ACHL_RS15835	COG1054	Belongs to the UPF0176 family
ACHL_RS15845	COG1111	helicase
ACHL_RS15845	COG1205	dead DEAH box helicase
ACHL_RS15885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACHL_RS15885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACHL_RS15910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACHL_RS15920	COG1175	transmembrane transport
ACHL_RS15925	COG0395	ABC-type sugar transport system, permease component
ACHL_RS15930	COG1349	DNA-binding transcription factor activity
ACHL_RS15935	COG1609	Transcriptional regulator
ACHL_RS15965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACHL_RS15970	COG1408	metallophosphoesterase
ACHL_RS15975	COG1132	(ABC) transporter
ACHL_RS15980	COG1132	(ABC) transporter
ACHL_RS16000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACHL_RS16005	COG0151	Belongs to the GarS family
ACHL_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS16040	COG1953	Uracil, thiamine, allantoin
ACHL_RS16045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACHL_RS16060	COG0667	Aldo Keto reductase
ACHL_RS16070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACHL_RS16080	COG3608	succinylglutamate desuccinylase aspartoacylase
ACHL_RS16080	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACHL_RS16085	COG2252	PERMEase
ACHL_RS16090	COG0590	tRNA wobble adenosine to inosine editing
ACHL_RS16100	COG3285	dna ligase
ACHL_RS16100	COG1793	dna ligase
ACHL_RS16115	COG2233	PERMEase
ACHL_RS16120	COG1414	Transcriptional regulator
ACHL_RS16130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACHL_RS16140	COG3257	ureidoglycine aminohydrolase activity
ACHL_RS16175	COG3387	PFAM Glycoside hydrolase 15-related
ACHL_RS16215	COG2267	carboxylic ester hydrolase activity
ACHL_RS16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS16245	COG0579	oxidoreductase
ACHL_RS16305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACHL_RS16320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACHL_RS16420	COG1609	Transcriptional regulator
ACHL_RS16425	COG1621	beta-fructofuranosidase activity
ACHL_RS16430	COG0395	ABC-type sugar transport system, permease component
ACHL_RS16435	COG1175	transmembrane transport
ACHL_RS16460	COG1064	alcohol dehydrogenase
ACHL_RS16475	COG2133	pyrroloquinoline quinone binding
ACHL_RS16485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACHL_RS16490	COG1116	anion transmembrane transporter activity
ACHL_RS16495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS16500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS16505	COG0667	Aldo Keto reductase
ACHL_RS16520	COG3739	integral membrane protein
ACHL_RS16575	COG0583	DNA-binding transcription factor activity
ACHL_RS16585	COG1414	Transcriptional regulator
ACHL_RS16595	COG0477	Major facilitator Superfamily
ACHL_RS16605	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS16620	COG1024	Enoyl-CoA hydratase
ACHL_RS16625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACHL_RS16630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACHL_RS16635	COG0477	Major facilitator Superfamily
ACHL_RS16640	COG1396	sequence-specific DNA binding
ACHL_RS16700	COG0454	-acetyltransferase
ACHL_RS16705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACHL_RS16725	COG1737	Transcriptional regulator
ACHL_RS16735	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS16760	COG0583	DNA-binding transcription factor activity
ACHL_RS16765	COG2828	Protein conserved in bacteria
ACHL_RS16785	COG3845	ABC transporter
ACHL_RS16795	COG0596	Alpha beta hydrolase
ACHL_RS16805	COG1410	methionine synthase
ACHL_RS16805	COG0646	methionine synthase
ACHL_RS16835	COG2814	Major facilitator Superfamily
ACHL_RS16835	COG0477	Major facilitator Superfamily
ACHL_RS16850	COG2159	amidohydrolase
ACHL_RS16860	COG2186	Transcriptional regulator
ACHL_RS16870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACHL_RS16875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACHL_RS16885	COG0129	dihydroxy-acid dehydratase activity
ACHL_RS16890	COG2329	Antibiotic biosynthesis monooxygenase
ACHL_RS16895	COG1028	Short-chain dehydrogenase reductase Sdr
ACHL_RS16905	COG2755	lipolytic protein G-D-S-L family
ACHL_RS16905	COG3401	FG-GAP repeat protein
ACHL_RS16925	COG1609	Transcriptional regulator
ACHL_RS16930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACHL_RS16945	COG2197	response regulator
ACHL_RS16950	COG4585	Histidine kinase
ACHL_RS16960	COG1136	(ABC) transporter
ACHL_RS16960	COG0577	efflux transmembrane transporter activity
ACHL_RS16980	COG4166	transmembrane transport
ACHL_RS16990	COG0444	Belongs to the ABC transporter superfamily
ACHL_RS16995	COG4608	Belongs to the ABC transporter superfamily
ACHL_RS17000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACHL_RS17005	COG1940	carbohydrate kinase activity
ACHL_RS17010	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ACHL_RS17065	COG0363	glucosamine-6-phosphate deaminase activity
ACHL_RS17105	COG3401	FG-GAP repeat protein
ACHL_RS17140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACHL_RS17155	COG1301	dicarboxylic acid transport
ACHL_RS17160	COG1414	Transcriptional regulator
ACHL_RS17165	COG2814	Major facilitator Superfamily
ACHL_RS17170	COG0402	S-adenosylhomocysteine deaminase activity
ACHL_RS17205	COG1473	amidohydrolase
ACHL_RS17210	COG0477	Major facilitator Superfamily
ACHL_RS17215	COG2354	Protein conserved in bacteria
ACHL_RS17220	COG3622	Belongs to the hyi family
ACHL_RS17225	COG2084	Dehydrogenase
ACHL_RS17230	COG3960	tartronate-semialdehyde synthase activity
ACHL_RS17235	COG1929	Belongs to the glycerate kinase type-1 family
ACHL_RS17240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACHL_RS17280	COG0745	RESPONSE REGULATOR receiver
ACHL_RS17290	COG1366	Belongs to the anti-sigma-factor antagonist family
ACHL_RS17300	COG2205	protein histidine kinase activity
ACHL_RS17310	COG2351	hydroxyisourate hydrolase activity
ACHL_RS17315	COG1414	Transcriptional regulator
ACHL_RS17320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACHL_RS17355	COG3404	Formiminotransferase-cyclodeaminase
ACHL_RS17360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACHL_RS17370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACHL_RS17375	COG2271	Major facilitator Superfamily
ACHL_RS17390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACHL_RS17410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACHL_RS17430	COG0542	response to heat
ACHL_RS17455	COG3585	molybdate ion transport
ACHL_RS17470	COG3304	Inner membrane component domain
ACHL_RS17475	COG0135	phosphoribosylanthranilate isomerase activity
ACHL_RS17485	COG1528	Iron-storage protein
ACHL_RS17510	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS17515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACHL_RS17535	COG2813	Specifically methylates the guanine in position
ACHL_RS17545	COG2807	transmembrane transport
ACHL_RS17555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACHL_RS17615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACHL_RS17640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACHL_RS17645	COG0069	glutamate synthase activity
ACHL_RS17650	COG2218	PFAM glutamate synthase alpha subunit domain protein
ACHL_RS17655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACHL_RS17665	COG1472	Belongs to the glycosyl hydrolase 3 family
ACHL_RS17700	COG1175	transmembrane transport
ACHL_RS17760	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS17770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACHL_RS17780	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACHL_RS17785	COG0583	DNA-binding transcription factor activity
ACHL_RS17800	COG1215	transferase activity, transferring glycosyl groups
ACHL_RS17815	COG3979	chitinase
ACHL_RS17825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACHL_RS17865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACHL_RS17870	COG1653	transport
ACHL_RS17875	COG1175	transmembrane transport
ACHL_RS17880	COG0395	ABC-type sugar transport system, permease component
ACHL_RS17905	COG3226	Transcriptional regulator
ACHL_RS17920	COG4977	sequence-specific DNA binding
ACHL_RS17925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACHL_RS17945	COG0738	Major facilitator superfamily
ACHL_RS17950	COG3226	Transcriptional regulator
ACHL_RS17955	COG0110	maltose O-acetyltransferase activity
ACHL_RS17965	COG1115	amino acid carrier protein
ACHL_RS17970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACHL_RS17975	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACHL_RS17980	COG1802	Transcriptional regulator
ACHL_RS17995	COG1760	l-serine dehydratase
ACHL_RS18020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACHL_RS18045	COG1175	transmembrane transport
ACHL_RS18050	COG0395	ABC-type sugar transport system, permease component
ACHL_RS18055	COG0366	Alpha amylase catalytic
ACHL_RS18070	COG1605	Chorismate mutase
ACHL_RS18070	COG0077	Prephenate dehydratase
ACHL_RS18100	COG3971	2-oxopent-4-enoate hydratase activity
ACHL_RS18115	COG0574	Belongs to the PEP-utilizing enzyme family
ACHL_RS18115	COG3848	Pyruvate phosphate dikinase
ACHL_RS18120	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS18130	COG0789	Transcriptional regulator
ACHL_RS18135	COG0484	heat shock protein binding
ACHL_RS18140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACHL_RS18145	COG0443	Heat shock 70 kDa protein
ACHL_RS18150	COG2066	Belongs to the glutaminase family
ACHL_RS18155	COG0640	Transcriptional regulator
ACHL_RS18160	COG2814	Major facilitator Superfamily
ACHL_RS18180	COG2409	Drug exporters of the RND superfamily
ACHL_RS18210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACHL_RS18220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACHL_RS18270	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACHL_RS18275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACHL_RS18290	COG1122	ATPase activity
ACHL_RS18295	COG4721	ABC-type cobalt transport system, permease component
ACHL_RS18310	COG1320	monovalent cation:proton antiporter activity
ACHL_RS18315	COG2212	antiporter activity
ACHL_RS18325	COG0651	ATP synthesis coupled electron transport
ACHL_RS18330	COG1006	Multisubunit Na H antiporter MnhC subunit
ACHL_RS18335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACHL_RS18335	COG2111	Na H antiporter
ACHL_RS18345	COG2985	domain, Protein
ACHL_RS18345	COG0569	domain protein
ACHL_RS18350	COG0475	glutathione-regulated potassium exporter activity
ACHL_RS18355	COG0717	Belongs to the dCTP deaminase family
ACHL_RS18390	COG0583	DNA-binding transcription factor activity
ACHL_RS18400	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS18405	COG0531	amino acid
ACHL_RS18410	COG0583	DNA-binding transcription factor activity
ACHL_RS18415	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACHL_RS18430	COG0477	Major facilitator Superfamily
ACHL_RS18435	COG3387	PFAM Glycoside hydrolase 15-related
ACHL_RS18440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS18445	COG0667	Aldo Keto reductase
ACHL_RS18455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACHL_RS18465	COG1012	belongs to the aldehyde dehydrogenase family
ACHL_RS18490	COG1063	alcohol dehydrogenase
ACHL_RS18520	COG0673	inositol 2-dehydrogenase activity
ACHL_RS18525	COG1609	Transcriptional regulator
ACHL_RS18550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS18555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS18565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS18575	COG1126	abc transporter atp-binding protein
ACHL_RS18580	COG0765	amino acid transport
ACHL_RS18595	COG0433	COG0433 Predicted ATPase
ACHL_RS18615	COG3336	cytochrome c oxidase
ACHL_RS18620	COG0776	regulation of translation
ACHL_RS18645	COG1609	Transcriptional regulator
ACHL_RS18665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACHL_RS18670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACHL_RS18675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACHL_RS18680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACHL_RS18680	COG1017	nitric oxide dioxygenase activity
ACHL_RS18715	COG1120	ATPase activity
ACHL_RS18720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACHL_RS18725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACHL_RS18775	COG3012	SEC-C Motif Domain Protein
ACHL_RS18785	COG0667	Aldo Keto reductase
ACHL_RS18790	COG0702	epimerase
ACHL_RS18805	COG1228	amidohydrolase
ACHL_RS18835	COG2186	Transcriptional regulator
ACHL_RS18845	COG1027	Aspartate ammonia-lyase
ACHL_RS18855	COG0405	Gamma-glutamyltransferase
ACHL_RS18860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACHL_RS18875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACHL_RS18895	COG1522	sequence-specific DNA binding
ACHL_RS18900	COG1280	lysine exporter protein (LysE YggA)
ACHL_RS18920	COG0281	malic enzyme
ACHL_RS18925	COG1309	transcriptional regulator
ACHL_RS18940	COG0477	Major facilitator Superfamily
ACHL_RS18945	COG0477	Major facilitator Superfamily
ACHL_RS18950	COG4133	protoheme IX ABC transporter activity
ACHL_RS18960	COG2814	Major facilitator Superfamily
ACHL_RS18975	COG4604	ABC transporter, ATP-binding protein
ACHL_RS18980	COG4605	iron ion homeostasis
ACHL_RS18985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACHL_RS18990	COG4607	ABC-type enterochelin transport system periplasmic component
ACHL_RS18995	COG0246	Mannitol dehydrogenase
ACHL_RS19010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACHL_RS19025	COG4608	Belongs to the ABC transporter superfamily
ACHL_RS19030	COG0444	Belongs to the ABC transporter superfamily
ACHL_RS19045	COG0601	transmembrane transport
ACHL_RS19050	COG0747	negative chemotaxis
ACHL_RS19065	COG0596	Alpha beta hydrolase
ACHL_RS19075	COG0686	Belongs to the AlaDH PNT family
ACHL_RS19080	COG0673	inositol 2-dehydrogenase activity
ACHL_RS19120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACHL_RS19140	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACHL_RS19145	COG0022	dehydrogenase e1 component
ACHL_RS19155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACHL_RS19160	COG2755	lipolytic protein G-D-S-L family
ACHL_RS19165	COG3866	Pectate lyase
ACHL_RS19170	COG1950	PFAM Membrane protein of
ACHL_RS19190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACHL_RS19195	COG0406	alpha-ribazole phosphatase activity
ACHL_RS19200	COG0515	serine threonine protein kinase
ACHL_RS19220	COG1607	acyl-coa hydrolase
ACHL_RS19225	COG1840	ABC-type Fe3 transport system, periplasmic component
ACHL_RS19230	COG3842	ATPase activity
ACHL_RS19235	COG1178	ABC-type Fe3 transport system permease component
ACHL_RS19245	COG1309	transcriptional regulator
ACHL_RS19255	COG1414	Transcriptional regulator
ACHL_RS19270	COG1597	lipid kinase activity
ACHL_RS19290	COG1414	Transcriptional regulator
ACHL_RS19295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACHL_RS19305	COG0183	Belongs to the thiolase family
ACHL_RS19310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACHL_RS19325	COG3485	protocatechuate 3,4-dioxygenase
ACHL_RS19330	COG3485	protocatechuate 3,4-dioxygenase
ACHL_RS19335	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ACHL_RS19335	COG1082	Xylose isomerase domain protein TIM barrel
ACHL_RS19340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACHL_RS19345	COG1414	Transcriptional regulator
ACHL_RS19355	COG1793	dna ligase
ACHL_RS19385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACHL_RS19415	COG1937	Protein conserved in bacteria
ACHL_RS19440	COG0697	spore germination
ACHL_RS19465	COG2259	Doxx family
ACHL_RS19475	COG0305	Participates in initiation and elongation during chromosome replication
ACHL_RS19485	COG0431	NADPH-dependent FMN reductase
ACHL_RS19490	COG0384	phenazine biosynthesis protein PhzF
ACHL_RS19500	COG0359	binds to the 23S rRNA
ACHL_RS19505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACHL_RS19515	COG0360	Binds together with S18 to 16S ribosomal RNA
ACHL_RS19520	COG1113	amino acid transport
ACHL_RS19530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACHL_RS19535	COG0673	inositol 2-dehydrogenase activity
ACHL_RS19545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACHL_RS19565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACHL_RS19570	COG1215	transferase activity, transferring glycosyl groups
ACHL_RS19610	COG1362	aminopeptidase activity
ACHL_RS19620	COG2197	response regulator
ACHL_RS19625	COG4585	Histidine kinase
ACHL_RS19645	COG0738	Major facilitator superfamily
ACHL_RS19650	COG0488	(ABC) transporter
ACHL_RS19655	COG0768	penicillin binding
ACHL_RS19670	COG0406	alpha-ribazole phosphatase activity
ACHL_RS19675	COG0617	tRNA 3'-terminal CCA addition
ACHL_RS19695	COG0492	ferredoxin-NADP+ reductase activity
ACHL_RS19700	COG3118	belongs to the thioredoxin family
ACHL_RS19710	COG1192	Involved in chromosome partitioning
ACHL_RS19715	COG0357	Ribosomal RNA small subunit methyltransferase G
ACHL_RS19725	COG0706	membrane insertase activity
ACHL_RS19730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACHL_RS19735	COG0594	ribonuclease P activity
ACHL_RS19750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACHL_RS19755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACHL_RS19820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACHL_RS19895	COG0512	Glutamine amidotransferase of anthranilate synthase
ACHL_RS20475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACHL_RS21140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACHL_RS21475	COG5001	Diguanylate cyclase
ACHL_RS21475	COG3706	GGDEF domain
ACHL_RS21475	COG2203	Gaf domain
ACHL_RS21475	COG4251	negative regulation of phosphorylation
ACHL_RS22065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACHL_RS22195	COG0542	response to heat
ACHL_RS22525	COG0829	nickel cation binding
ACHL_RS22605	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ACHL_RS23155	COG0457	Tetratricopeptide repeat
ACHL_RS23160	COG0457	Tetratricopeptide repeat
ACHL_RS23365	COG1595	DNA-templated transcription, initiation
ACHL_RS23405	COG1404	Belongs to the peptidase S8 family
ACHL_RS23485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner