locus-tag	class	description
CPA52_RS00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CPA52_RS00015	COG0594	ribonuclease P activity
CPA52_RS00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CPA52_RS00025	COG0706	membrane insertase activity
CPA52_RS00030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CPA52_RS00040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CPA52_RS00045	COG0445	tRNA wobble uridine modification
CPA52_RS00050	COG0357	Ribosomal RNA small subunit methyltransferase G
CPA52_RS00055	COG1192	Involved in chromosome partitioning
CPA52_RS00060	COG1475	DNA binding
CPA52_RS00070	COG0356	it plays a direct role in the translocation of protons across the membrane
CPA52_RS00080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CPA52_RS00085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPA52_RS00090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CPA52_RS00095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CPA52_RS00100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CPA52_RS00105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CPA52_RS00110	COG3710	Transcriptional regulator
CPA52_RS00115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CPA52_RS00150	COG0110	maltose O-acetyltransferase activity
CPA52_RS00155	COG1349	DNA-binding transcription factor activity
CPA52_RS00160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CPA52_RS00170	COG0513	Belongs to the DEAD box helicase family
CPA52_RS00200	COG1278	Cold shock
CPA52_RS00205	COG1278	Cold shock
CPA52_RS00210	COG2855	membrane
CPA52_RS00220	COG0656	L-ascorbic acid biosynthetic process
CPA52_RS00225	COG2188	Transcriptional regulator
CPA52_RS00230	COG0730	response to heat
CPA52_RS00240	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPA52_RS00245	COG4771	TonB-dependent receptor
CPA52_RS00255	COG1785	Belongs to the alkaline phosphatase family
CPA52_RS00320	COG2832	Protein of unknown function (DUF454)
CPA52_RS00335	COG0676	glucose-6-phosphate 1-epimerase activity
CPA52_RS00345	COG3428	Bacterial PH domain
CPA52_RS00410	COG1404	Belongs to the peptidase S8 family
CPA52_RS00415	COG1770	oligopeptidase
CPA52_RS00420	COG0784	Response regulator, receiver
CPA52_RS00420	COG5002	protein histidine kinase activity
CPA52_RS00425	COG0745	RESPONSE REGULATOR receiver
CPA52_RS00445	COG1238	metal cluster binding
CPA52_RS00450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CPA52_RS00455	COG0302	gtp cyclohydrolase
CPA52_RS00460	COG1028	Short-chain dehydrogenase reductase Sdr
CPA52_RS00465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPA52_RS00470	COG3132	Protein of unknown function, DUF480
CPA52_RS00475	COG0784	Response regulator, receiver
CPA52_RS00475	COG5002	protein histidine kinase activity
CPA52_RS00475	COG2205	protein histidine kinase activity
CPA52_RS00480	COG1944	ATP diphosphatase activity
CPA52_RS00490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPA52_RS00495	COG3153	acetyltransferase
CPA52_RS00495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPA52_RS00530	COG1187	pseudouridine synthase activity
CPA52_RS00550	COG1011	Hydrolase
CPA52_RS00555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CPA52_RS00565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPA52_RS00570	COG0019	diaminopimelate decarboxylase activity
CPA52_RS00580	COG1965	Belongs to the frataxin family
CPA52_RS00585	COG0400	carboxylic ester hydrolase activity
CPA52_RS00595	COG0181	hydroxymethylbilane synthase activity
CPA52_RS00610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CPA52_RS00615	COG0517	IMP dehydrogenase activity
CPA52_RS00615	COG0516	GMP reductase activity
CPA52_RS00625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CPA52_RS00640	COG2354	Protein conserved in bacteria
CPA52_RS00655	COG4774	siderophore transport
CPA52_RS00660	COG0513	Belongs to the DEAD box helicase family
CPA52_RS00670	COG0784	Response regulator, receiver
CPA52_RS00670	COG2205	protein histidine kinase activity
CPA52_RS00670	COG2198	Histidine kinase
CPA52_RS00680	COG3118	belongs to the thioredoxin family
CPA52_RS00685	COG0513	Belongs to the DEAD box helicase family
CPA52_RS00690	COG0248	Ppx GppA phosphatase
CPA52_RS00720	COG1444	tRNA N-acetyltransferase activity
CPA52_RS00725	COG0210	DNA helicase
CPA52_RS00735	COG3112	Uncharacterised protein family (UPF0231)
CPA52_RS00745	COG1011	Hydrolase
CPA52_RS00750	COG0494	nUDIX hydrolase
CPA52_RS00755	COG1218	3'(2'),5'-bisphosphate nucleotidase
CPA52_RS00780	COG0606	chelatase, subunit chli
CPA52_RS00790	COG0823	Involved in the tonB-independent uptake of proteins
CPA52_RS00790	COG1506	peptidase
CPA52_RS00795	COG1253	flavin adenine dinucleotide binding
CPA52_RS00805	COG2031	fatty acid transporter
CPA52_RS00825	COG1946	Acyl-CoA thioesterase
CPA52_RS00830	COG2937	Belongs to the GPAT DAPAT family
CPA52_RS00835	COG0051	transcription antitermination factor activity, RNA binding
CPA52_RS00840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CPA52_RS00845	COG0088	Forms part of the polypeptide exit tunnel
CPA52_RS00850	COG0089	rRNA binding
CPA52_RS00855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPA52_RS00860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CPA52_RS00865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CPA52_RS00870	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CPA52_RS00875	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CPA52_RS00880	COG0255	Belongs to the universal ribosomal protein uL29 family
CPA52_RS00885	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CPA52_RS00905	COG2356	endonuclease I
CPA52_RS00910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CPA52_RS00915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CPA52_RS00940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CPA52_RS00970	COG2204	response regulator
CPA52_RS00975	COG3852	Histidine kinase
CPA52_RS00985	COG0174	glutamine synthetase
CPA52_RS00990	COG1217	gtp-binding protein TYPA
CPA52_RS01020	COG1295	ribonuclease BN
CPA52_RS01025	COG1490	D-aminoacyl-tRNA deacylase activity
CPA52_RS01035	COG0456	acetyltransferase
CPA52_RS01040	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CPA52_RS01050	COG0019	diaminopimelate decarboxylase activity
CPA52_RS01060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPA52_RS01070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CPA52_RS01080	COG1049	propionate catabolic process, 2-methylcitrate cycle
CPA52_RS01105	COG2017	converts alpha-aldose to the beta-anomer
CPA52_RS01125	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPA52_RS01135	COG2186	Transcriptional regulator
CPA52_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
CPA52_RS01145	COG3734	2-keto-3-deoxy-galactonokinase
CPA52_RS01150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CPA52_RS01170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CPA52_RS01180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CPA52_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
CPA52_RS01205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CPA52_RS01215	COG1012	belongs to the aldehyde dehydrogenase family
CPA52_RS01225	COG1765	OsmC-like protein
CPA52_RS01230	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CPA52_RS01240	COG0814	amino acid
CPA52_RS01260	COG2267	carboxylic ester hydrolase activity
CPA52_RS01280	COG1218	3'(2'),5'-bisphosphate nucleotidase
CPA52_RS01285	COG0529	Catalyzes the synthesis of activated sulfate
CPA52_RS01290	COG0471	metal ion transport
CPA52_RS01290	COG3273	potassium ion transport
CPA52_RS01295	COG2895	sulfate adenylyltransferase (ATP) activity
CPA52_RS01300	COG0175	sulfate reduction
CPA52_RS01305	COG1648	precorrin-2 dehydrogenase activity
CPA52_RS01305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CPA52_RS01310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CPA52_RS01325	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPA52_RS01330	COG0250	Participates in transcription elongation, termination and antitermination
CPA52_RS01335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CPA52_RS01340	COG0081	regulation of translation
CPA52_RS01345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CPA52_RS01350	COG0222	ribosome binding
CPA52_RS01355	COG0085	RNA polymerase activity
CPA52_RS01360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPA52_RS01365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CPA52_RS01370	COG0049	tRNA binding
CPA52_RS01375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPA52_RS01380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPA52_RS01385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPA52_RS01385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CPA52_RS01400	COG1131	(ABC) transporter
CPA52_RS01420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CPA52_RS01430	COG0459	protein refolding
CPA52_RS01435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CPA52_RS01440	COG3030	protein affecting phage T7 exclusion by the F plasmid
CPA52_RS01445	COG1324	tolerance protein
CPA52_RS01450	COG4232	protein-disulfide reductase activity
CPA52_RS01455	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CPA52_RS01460	COG0511	ligase activity, forming carbon-carbon bonds
CPA52_RS01465	COG0439	Biotin carboxylase
CPA52_RS01470	COG0802	atpase or kinase
CPA52_RS01475	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPA52_RS01480	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CPA52_RS01485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPA52_RS01490	COG1923	regulation of RNA biosynthetic process
CPA52_RS01495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPA52_RS01500	COG0330	HflC and HflK could
CPA52_RS01505	COG0330	HflC and HflK could
CPA52_RS01510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CPA52_RS01515	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CPA52_RS01525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CPA52_RS01530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CPA52_RS01540	COG2205	protein histidine kinase activity
CPA52_RS01540	COG0784	Response regulator, receiver
CPA52_RS01570	COG3122	Protein conserved in bacteria
CPA52_RS01585	COG4948	Mandelate Racemase Muconate Lactonizing
CPA52_RS01610	COG0741	lytic transglycosylase activity
CPA52_RS01610	COG1388	LysM domain
CPA52_RS01630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CPA52_RS01635	COG2824	Alkylphosphonate utilization operon protein PhnA
CPA52_RS01645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CPA52_RS01670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPA52_RS01680	COG0248	Ppx GppA phosphatase
CPA52_RS01700	COG0573	inorganic phosphate transmembrane transporter activity
CPA52_RS01705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CPA52_RS01715	COG1392	Phosphate transport regulator
CPA52_RS01720	COG0306	phosphate transporter
CPA52_RS01725	COG0583	DNA-binding transcription factor activity
CPA52_RS01735	COG5001	Diguanylate cyclase
CPA52_RS01735	COG5002	protein histidine kinase activity
CPA52_RS01740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CPA52_RS01745	COG0343	queuine tRNA-ribosyltransferase activity
CPA52_RS01750	COG1862	Preprotein translocase
CPA52_RS01755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPA52_RS01760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPA52_RS01790	COG2823	Periplasmic or secreted lipoprotein
CPA52_RS01815	COG0583	DNA-binding transcription factor activity
CPA52_RS01835	COG1280	lysine exporter protein (LysE YggA)
CPA52_RS01850	COG0123	including yeast histone deacetylase and acetoin utilization protein
CPA52_RS01870	COG0151	Belongs to the GarS family
CPA52_RS01880	COG0138	bifunctional purine biosynthesis protein purh
CPA52_RS01885	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CPA52_RS01890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPA52_RS01895	COG2264	protein methyltransferase activity
CPA52_RS01900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPA52_RS01915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CPA52_RS01920	COG0742	ribosomal rna small subunit methyltransferase
CPA52_RS01925	COG0552	protein localization to endoplasmic reticulum
CPA52_RS01930	COG2884	Cell division ATP-binding protein ftsE
CPA52_RS01935	COG2177	Part of the ABC transporter FtsEX involved in
CPA52_RS01960	COG0793	Belongs to the peptidase S41A family
CPA52_RS01965	COG4942	peptidase
CPA52_RS01970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CPA52_RS01975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPA52_RS01980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPA52_RS01985	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CPA52_RS01990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CPA52_RS01995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CPA52_RS02010	COG2205	protein histidine kinase activity
CPA52_RS02015	COG0745	RESPONSE REGULATOR receiver
CPA52_RS02025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CPA52_RS02030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPA52_RS02035	COG0237	dephospho-CoA kinase activity
CPA52_RS02060	COG0157	Belongs to the NadC ModD family
CPA52_RS02065	COG3023	N-Acetylmuramoyl-L-alanine amidase
CPA52_RS02070	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CPA52_RS02075	COG2186	Transcriptional regulator
CPA52_RS02080	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CPA52_RS02085	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPA52_RS02090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPA52_RS02095	COG3148	PFAM DTW domain containing protein
CPA52_RS02100	COG1840	ABC-type Fe3 transport system, periplasmic component
CPA52_RS02110	COG3842	ATPase activity
CPA52_RS02120	COG1438	arginine binding
CPA52_RS02125	COG0039	L-malate dehydrogenase activity
CPA52_RS02130	COG0142	geranyltranstransferase activity
CPA52_RS02135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CPA52_RS02140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CPA52_RS02145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPA52_RS02160	COG1506	peptidase
CPA52_RS02160	COG0823	Involved in the tonB-independent uptake of proteins
CPA52_RS02160	COG4946	Tricorn protease homolog
CPA52_RS02175	COG2003	Belongs to the UPF0758 family
CPA52_RS02185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CPA52_RS02190	COG1404	Belongs to the peptidase S8 family
CPA52_RS02195	COG2081	HI0933 family
CPA52_RS02205	COG1227	inorganic diphosphatase activity
CPA52_RS02215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPA52_RS02220	COG0840	transmembrane signaling receptor activity
CPA52_RS02225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CPA52_RS02230	COG2967	ApaG domain
CPA52_RS02235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CPA52_RS02240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CPA52_RS02245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPA52_RS02250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CPA52_RS02265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CPA52_RS02275	COG0564	pseudouridine synthase activity
CPA52_RS02285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CPA52_RS02290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CPA52_RS02295	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CPA52_RS02320	COG2826	transposase and inactivated derivatives, IS30 family
CPA52_RS02355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CPA52_RS02360	COG2205	protein histidine kinase activity
CPA52_RS02360	COG3437	response regulator, receiver
CPA52_RS02360	COG3850	Histidine kinase
CPA52_RS02360	COG4999	Histidine kinase
CPA52_RS02365	COG4251	negative regulation of phosphorylation
CPA52_RS02365	COG3706	GGDEF domain
CPA52_RS02365	COG2203	Gaf domain
CPA52_RS02365	COG5001	Diguanylate cyclase
CPA52_RS02375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPA52_RS02380	COG0789	Transcriptional regulator
CPA52_RS02385	COG0701	Predicted permease
CPA52_RS02395	COG3313	Fe-S protein
CPA52_RS02420	COG0045	succinate-CoA ligase (ADP-forming) activity
CPA52_RS02420	COG1042	CoA-binding domain protein
CPA52_RS02420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPA52_RS02440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPA52_RS02445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CPA52_RS02455	COG0762	integral membrane protein
CPA52_RS02460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPA52_RS02465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPA52_RS02480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPA52_RS02485	COG1678	Uncharacterized ACR, COG1678
CPA52_RS02495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CPA52_RS02510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CPA52_RS02520	COG1560	Kdo2-lipid A biosynthetic process
CPA52_RS02525	COG1538	Outer membrane efflux protein
CPA52_RS02530	COG0494	nUDIX hydrolase
CPA52_RS02535	COG3151	Protein conserved in bacteria
CPA52_RS02545	COG3150	esterase
CPA52_RS02565	COG0204	Acyl-transferase
CPA52_RS02570	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CPA52_RS02580	COG0189	ligase activity
CPA52_RS02580	COG4067	protein conserved in archaea
CPA52_RS02585	COG0189	ligase activity
CPA52_RS02610	COG0514	ATP-dependent DNA helicase (RecQ)
CPA52_RS02615	COG2050	protein possibly involved in aromatic compounds catabolism
CPA52_RS02620	COG2962	Rard protein
CPA52_RS02630	COG3085	chromosome segregation
CPA52_RS02635	COG0583	DNA-binding transcription factor activity
CPA52_RS02645	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CPA52_RS02650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPA52_RS02655	COG1492	cobalamin metabolic process
CPA52_RS02660	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CPA52_RS02665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPA52_RS02670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CPA52_RS02685	COG3022	response to hydroperoxide
CPA52_RS02695	COG0668	transmembrane transport
CPA52_RS02705	COG0513	Belongs to the DEAD box helicase family
CPA52_RS02710	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CPA52_RS02720	COG0716	FMN binding
CPA52_RS02730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CPA52_RS02735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CPA52_RS02745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPA52_RS02775	COG3876	Protein conserved in bacteria
CPA52_RS02780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CPA52_RS02785	COG1757	Na H antiporter
CPA52_RS02815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CPA52_RS02830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPA52_RS02840	COG2137	regulation of response to DNA damage stimulus
CPA52_RS02845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPA52_RS02855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CPA52_RS02875	COG3630	sodium ion export across plasma membrane
CPA52_RS02890	COG4989	oxidoreductase activity
CPA52_RS02900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CPA52_RS02910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPA52_RS02920	COG1469	GTP cyclohydrolase I activity
CPA52_RS02925	COG0784	Response regulator, receiver
CPA52_RS02925	COG2198	Histidine kinase
CPA52_RS02925	COG5002	protein histidine kinase activity
CPA52_RS02930	COG0745	RESPONSE REGULATOR receiver
CPA52_RS02935	COG4191	Histidine kinase
CPA52_RS02935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPA52_RS02940	COG2813	Specifically methylates the guanine in position
CPA52_RS02945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CPA52_RS02950	COG1194	a g-specific adenine glycosylase
CPA52_RS02955	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CPA52_RS02960	COG2205	protein histidine kinase activity
CPA52_RS02960	COG0784	Response regulator, receiver
CPA52_RS02960	COG5002	protein histidine kinase activity
CPA52_RS03020	COG0006	proline dipeptidase activity
CPA52_RS03025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CPA52_RS03030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CPA52_RS03045	COG0360	Binds together with S18 to 16S ribosomal RNA
CPA52_RS03050	COG2965	DNA replication, synthesis of RNA primer
CPA52_RS03055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CPA52_RS03060	COG0359	binds to the 23S rRNA
CPA52_RS03065	COG1595	DNA-templated transcription, initiation
CPA52_RS03080	COG0305	Participates in initiation and elongation during chromosome replication
CPA52_RS03085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CPA52_RS03120	COG5002	protein histidine kinase activity
CPA52_RS03120	COG5001	Diguanylate cyclase
CPA52_RS03140	COG0525	valine-tRNA ligase activity
CPA52_RS03145	COG2927	DNA polymerase III (CHI subunit)
CPA52_RS03150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPA52_RS03155	COG0795	lipopolysaccharide-transporting ATPase activity
CPA52_RS03160	COG0795	lipopolysaccharide-transporting ATPase activity
CPA52_RS03175	COG4251	negative regulation of phosphorylation
CPA52_RS03175	COG3706	GGDEF domain
CPA52_RS03175	COG2203	Gaf domain
CPA52_RS03175	COG5001	Diguanylate cyclase
CPA52_RS03200	COG4989	oxidoreductase activity
CPA52_RS03215	COG1473	amidohydrolase
CPA52_RS03235	COG4206	TonB-dependent receptor
CPA52_RS03285	COG1012	belongs to the aldehyde dehydrogenase family
CPA52_RS03295	COG2204	response regulator
CPA52_RS03305	COG4251	negative regulation of phosphorylation
CPA52_RS03310	COG0784	Response regulator, receiver
CPA52_RS03315	COG2198	Histidine kinase
CPA52_RS03315	COG0784	Response regulator, receiver
CPA52_RS03315	COG2205	protein histidine kinase activity
CPA52_RS03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPA52_RS03320	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPA52_RS03330	COG0667	Aldo Keto reductase
CPA52_RS03340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CPA52_RS03345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPA52_RS03350	COG0840	transmembrane signaling receptor activity
CPA52_RS03380	COG2974	May be involved in recombination
CPA52_RS03385	COG4191	Histidine kinase
CPA52_RS03390	COG2201	protein-glutamate methylesterase activity
CPA52_RS03405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CPA52_RS03410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CPA52_RS03415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CPA52_RS03420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPA52_RS03420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPA52_RS03435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CPA52_RS03440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPA52_RS03450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CPA52_RS03465	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CPA52_RS03470	COG0142	geranyltranstransferase activity
CPA52_RS03475	COG1722	exodeoxyribonuclease VII activity
CPA52_RS03480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CPA52_RS03490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPA52_RS03495	COG1473	amidohydrolase
CPA52_RS03500	COG3118	belongs to the thioredoxin family
CPA52_RS03525	COG2066	Belongs to the glutaminase family
CPA52_RS03530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPA52_RS03540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CPA52_RS03545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPA52_RS03545	COG0047	phosphoribosylformylglycinamidine synthase activity
CPA52_RS03560	COG3784	Protein of unknown function (DUF1318)
CPA52_RS03570	COG1519	Transferase
CPA52_RS03575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CPA52_RS03580	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CPA52_RS03580	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CPA52_RS03600	COG3642	lipopolysaccharide core region biosynthetic process
CPA52_RS03605	COG0859	PFAM glycosyl transferase family 9
CPA52_RS03610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CPA52_RS03620	COG1063	alcohol dehydrogenase
CPA52_RS03625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPA52_RS03630	COG0705	Rhomboid family
CPA52_RS03640	COG3161	chorismate lyase activity
CPA52_RS03645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CPA52_RS03655	COG0583	DNA-binding transcription factor activity
CPA52_RS03675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CPA52_RS03680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CPA52_RS03690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPA52_RS03695	COG1968	undecaprenyl-diphosphatase activity
CPA52_RS03705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPA52_RS03710	COG0163	prenyltransferase activity
CPA52_RS03715	COG1131	(ABC) transporter
CPA52_RS03720	COG0842	Transport permease protein
CPA52_RS03725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CPA52_RS03730	COG2199	diguanylate cyclase activity
CPA52_RS03730	COG2200	EAL domain
CPA52_RS03730	COG3287	FIST C domain
CPA52_RS03735	COG0076	glutamate decarboxylase activity
CPA52_RS03745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CPA52_RS03760	COG0137	argininosuccinate synthase activity
CPA52_RS03765	COG0165	Argininosuccinate lyase
CPA52_RS03765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CPA52_RS03810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CPA52_RS03820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPA52_RS03820	COG0301	tRNA thio-modification
CPA52_RS03835	COG1666	GTP binding
CPA52_RS03840	COG4206	TonB-dependent receptor
CPA52_RS03850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPA52_RS03880	COG3409	Peptidoglycan-binding domain 1 protein
CPA52_RS03880	COG3267	Type II secretory pathway component ExeA
CPA52_RS03895	COG0506	proline dehydrogenase activity
CPA52_RS03895	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CPA52_RS03895	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CPA52_RS03905	COG2239	Acts as a magnesium transporter
CPA52_RS03920	COG3025	triphosphatase activity
CPA52_RS03945	COG0004	ammonium transporteR
CPA52_RS03950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPA52_RS03955	COG0840	transmembrane signaling receptor activity
CPA52_RS03960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CPA52_RS03965	COG0540	Belongs to the ATCase OTCase family
CPA52_RS03970	COG1981	membrane
CPA52_RS03980	COG0316	Belongs to the HesB IscA family
CPA52_RS03995	COG2211	Major facilitator Superfamily
CPA52_RS04010	COG2813	Specifically methylates the guanine in position
CPA52_RS04020	COG0271	Belongs to the BolA IbaG family
CPA52_RS04025	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CPA52_RS04030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CPA52_RS04035	COG1805	sodium ion transport
CPA52_RS04040	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CPA52_RS04045	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CPA52_RS04050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CPA52_RS04055	COG2871	sodium ion transport
CPA52_RS04060	COG1477	protein flavinylation
CPA52_RS04065	COG2991	Protein conserved in bacteria
CPA52_RS04095	COG0123	including yeast histone deacetylase and acetoin utilization protein
CPA52_RS04105	COG0488	(ABC) transporter
CPA52_RS04115	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CPA52_RS04120	COG1410	methionine synthase
CPA52_RS04120	COG0646	methionine synthase
CPA52_RS04125	COG1410	methionine synthase
CPA52_RS04125	COG0646	methionine synthase
CPA52_RS04140	COG1794	racemase activity, acting on amino acids and derivatives
CPA52_RS04155	COG3237	CsbD-like
CPA52_RS04160	COG1643	Atp-dependent helicase
CPA52_RS04180	COG4191	Histidine kinase
CPA52_RS04185	COG5001	Diguanylate cyclase
CPA52_RS04185	COG4251	negative regulation of phosphorylation
CPA52_RS04185	COG2203	Gaf domain
CPA52_RS04185	COG3706	GGDEF domain
CPA52_RS04210	COG1064	alcohol dehydrogenase
CPA52_RS04215	COG2814	Major facilitator Superfamily
CPA52_RS04230	COG1476	TRANSCRIPTIONal
CPA52_RS04260	COG2255	four-way junction helicase activity
CPA52_RS04265	COG2200	EAL domain
CPA52_RS04265	COG2199	diguanylate cyclase activity
CPA52_RS04265	COG2202	Pas domain
CPA52_RS04275	COG1764	response to oxidative stress
CPA52_RS04285	COG0415	Belongs to the DNA photolyase family
CPA52_RS04290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CPA52_RS04295	COG0657	acetylesterase activity
CPA52_RS04300	COG2205	protein histidine kinase activity
CPA52_RS04305	COG0745	RESPONSE REGULATOR receiver
CPA52_RS04335	COG0625	glutathione transferase activity
CPA52_RS04350	COG0583	DNA-binding transcription factor activity
CPA52_RS04370	COG0339	signal peptide processing
CPA52_RS04375	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CPA52_RS04375	COG3264	Mechanosensitive ion channel
CPA52_RS04380	COG4771	TonB-dependent receptor
CPA52_RS04395	COG1793	dna ligase
CPA52_RS04400	COG0443	Heat shock 70 kDa protein
CPA52_RS04405	COG1803	Methylglyoxal synthase
CPA52_RS04435	COG0739	heme binding
CPA52_RS04440	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPA52_RS04465	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CPA52_RS04475	COG1215	transferase activity, transferring glycosyl groups
CPA52_RS04495	COG2194	sulfuric ester hydrolase activity
CPA52_RS04525	COG4133	protoheme IX ABC transporter activity
CPA52_RS04530	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPA52_RS04535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPA52_RS04540	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPA52_RS04545	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CPA52_RS04550	COG1138	Cytochrome C-type biogenesis protein
CPA52_RS04560	COG3088	subunit of a heme lyase
CPA52_RS04560	COG4235	cytochrome complex assembly
CPA52_RS04570	COG2853	Lipoprotein
CPA52_RS04575	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CPA52_RS04580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPA52_RS04585	COG3141	response to X-ray
CPA52_RS04590	COG1555	photosystem II stabilization
CPA52_RS04600	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CPA52_RS04620	COG3547	Transposase (IS116 IS110 IS902 family)
CPA52_RS04650	COG0450	alkyl hydroperoxide reductase
CPA52_RS04655	COG4206	TonB-dependent receptor
CPA52_RS04660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CPA52_RS04665	COG2867	negative regulation of translational initiation
CPA52_RS04670	COG2914	Belongs to the UPF0125 (RnfH) family
CPA52_RS04675	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPA52_RS04700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CPA52_RS04705	COG0583	DNA-binding transcription factor activity
CPA52_RS04725	COG0745	RESPONSE REGULATOR receiver
CPA52_RS04745	COG4326	sporulation control protein
CPA52_RS04750	COG2153	protein acetylation
CPA52_RS04755	COG0733	neurotransmitter:sodium symporter activity
CPA52_RS04765	COG0745	RESPONSE REGULATOR receiver
CPA52_RS04795	COG1534	Rna-binding protein
CPA52_RS04800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CPA52_RS04805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPA52_RS04810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CPA52_RS04815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPA52_RS04820	COG0149	triose-phosphate isomerase activity
CPA52_RS04825	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPA52_RS04855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPA52_RS04870	COG0101	tRNA pseudouridine synthase activity
CPA52_RS04875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CPA52_RS04880	COG0285	dihydrofolate synthase activity
CPA52_RS04890	COG1286	toxin biosynthetic process
CPA52_RS04895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CPA52_RS04910	COG2203	Gaf domain
CPA52_RS04910	COG4251	negative regulation of phosphorylation
CPA52_RS04910	COG3706	GGDEF domain
CPA52_RS04910	COG5001	Diguanylate cyclase
CPA52_RS04915	COG3852	Histidine kinase
CPA52_RS04925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPA52_RS04930	COG0215	cysteine-tRNA ligase activity
CPA52_RS04935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CPA52_RS04965	COG0544	peptidyl-prolyl cis-trans isomerase activity
CPA52_RS04970	COG0740	serine-type endopeptidase activity
CPA52_RS04975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CPA52_RS04980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CPA52_RS04990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPA52_RS04995	COG2514	catechol 2,3-dioxygenase activity
CPA52_RS05000	COG4172	Belongs to the ABC transporter superfamily
CPA52_RS05010	COG4171	peptide transport system, permease
CPA52_RS05020	COG0747	negative chemotaxis
CPA52_RS05025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CPA52_RS05030	COG1842	Phage shock protein A
CPA52_RS05040	COG1983	PspC domain protein
CPA52_RS05045	COG3106	COG3106 Predicted ATPase
CPA52_RS05055	COG0626	cystathionine gamma-synthase activity
CPA52_RS05065	COG2154	pterin-4-alpha-carbinolamine dehydratase
CPA52_RS05075	COG2171	N-acyltransferase activity
CPA52_RS05080	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CPA52_RS05085	COG0024	Methionine aminopeptidase
CPA52_RS05090	COG0052	Belongs to the universal ribosomal protein uS2 family
CPA52_RS05095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CPA52_RS05100	COG0528	UMP kinase activity
CPA52_RS05105	COG0233	cytoplasmic translational termination
CPA52_RS05110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPA52_RS05115	COG0575	Belongs to the CDS family
CPA52_RS05120	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CPA52_RS05125	COG0750	zinc metalloprotease
CPA52_RS05140	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPA52_RS05145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CPA52_RS05150	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPA52_RS05155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPA52_RS05160	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CPA52_RS05165	COG4988	ABC transporter
CPA52_RS05170	COG4890	Cyd operon protein YbgT
CPA52_RS05175	COG1294	oxidase, subunit
CPA52_RS05185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CPA52_RS05190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CPA52_RS05195	COG0587	DNA-directed DNA polymerase activity
CPA52_RS05200	COG0825	malonyl-CoA metabolic process
CPA52_RS05205	COG0037	tRNA processing
CPA52_RS05240	COG0784	Response regulator, receiver
CPA52_RS05240	COG2205	protein histidine kinase activity
CPA52_RS05250	COG0523	cobalamin synthesis protein
CPA52_RS05260	COG0668	transmembrane transport
CPA52_RS05270	COG2391	methyltransferase activity
CPA52_RS05280	COG0477	Major facilitator Superfamily
CPA52_RS05325	COG2176	DNA-directed DNA polymerase activity
CPA52_RS05340	COG1404	Belongs to the peptidase S8 family
CPA52_RS05380	COG0123	including yeast histone deacetylase and acetoin utilization protein
CPA52_RS05390	COG0730	response to heat
CPA52_RS05395	COG1199	ATP-dependent helicase activity
CPA52_RS05400	COG0417	DNA replication proofreading
CPA52_RS05405	COG4206	TonB-dependent receptor
CPA52_RS05420	COG1061	Type III restriction enzyme res subunit
CPA52_RS05430	COG0729	surface antigen
CPA52_RS05445	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CPA52_RS05445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CPA52_RS05455	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CPA52_RS05485	COG3098	single-species biofilm formation
CPA52_RS05490	COG0564	pseudouridine synthase activity
CPA52_RS05500	COG0741	lytic transglycosylase activity
CPA52_RS05500	COG1388	LysM domain
CPA52_RS05505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPA52_RS05510	COG2226	methyltransferase
CPA52_RS05515	COG0328	RNA-DNA hybrid ribonuclease activity
CPA52_RS05520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CPA52_RS05570	COG1116	anion transmembrane transporter activity
CPA52_RS05580	COG1960	acyl-CoA dehydrogenase activity
CPA52_RS05585	COG0121	glutamine amidotransferase
CPA52_RS05595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CPA52_RS05600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CPA52_RS05605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CPA52_RS05610	COG2226	methyltransferase
CPA52_RS05620	COG1451	nucleotide metabolic process
CPA52_RS05625	COG1801	Protein of unknown function DUF72
CPA52_RS05630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CPA52_RS05660	COG0513	Belongs to the DEAD box helicase family
CPA52_RS05680	COG2816	NAD+ diphosphatase activity
CPA52_RS05685	COG0626	cystathionine gamma-synthase activity
CPA52_RS05710	COG1960	acyl-CoA dehydrogenase activity
CPA52_RS05720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPA52_RS05725	COG1823	symporter activity
CPA52_RS05730	COG2197	response regulator
CPA52_RS05735	COG0322	excinuclease ABC activity
CPA52_RS05790	COG1115	amino acid carrier protein
CPA52_RS05820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CPA52_RS05825	COG0072	phenylalanine-tRNA ligase activity
CPA52_RS05830	COG0776	regulation of translation
CPA52_RS05845	COG2866	Carboxypeptidase
CPA52_RS05850	COG1115	amino acid carrier protein
CPA52_RS05860	COG3139	Protein of unknown function (DUF1315)
CPA52_RS05900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CPA52_RS05905	COG1288	antiporter activity
CPA52_RS05910	COG4206	TonB-dependent receptor
CPA52_RS05935	COG2755	lipolytic protein G-D-S-L family
CPA52_RS05940	COG4181	ATPase activity
CPA52_RS05945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CPA52_RS05950	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CPA52_RS05955	COG0632	four-way junction helicase activity
CPA52_RS05960	COG2255	four-way junction helicase activity
CPA52_RS05965	COG0811	peptide transport
CPA52_RS05980	COG0823	Involved in the tonB-independent uptake of proteins
CPA52_RS05985	COG2885	chlorophyll binding
CPA52_RS05990	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CPA52_RS06035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CPA52_RS06045	COG2199	diguanylate cyclase activity
CPA52_RS06050	COG0784	Response regulator, receiver
CPA52_RS06050	COG5002	protein histidine kinase activity
CPA52_RS06065	COG1902	pentaerythritol trinitrate reductase activity
CPA52_RS06085	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CPA52_RS06095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPA52_RS06120	COG0037	tRNA processing
CPA52_RS06125	COG0589	response to stress
CPA52_RS06130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPA52_RS06145	COG2217	Heavy metal translocating P-type atpase
CPA52_RS06155	COG2010	Cytochrome c
CPA52_RS06170	COG3278	Belongs to the heme-copper respiratory oxidase family
CPA52_RS06200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPA52_RS06205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPA52_RS06210	COG2957	Belongs to the agmatine deiminase family
CPA52_RS06225	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPA52_RS06230	COG0583	DNA-binding transcription factor activity
CPA52_RS06255	COG0848	biopolymer transport protein
CPA52_RS06270	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CPA52_RS06280	COG3083	sulfuric ester hydrolase activity
CPA52_RS06285	COG3082	Protein of unknown function (DUF1414)
CPA52_RS06290	COG3081	Nucleoid-associated protein
CPA52_RS06295	COG1530	ribonuclease E activity
CPA52_RS06305	COG0546	phosphoglycolate phosphatase activity
CPA52_RS06310	COG0424	maF-like protein
CPA52_RS06315	COG1399	metal-binding, possibly nucleic acid-binding protein
CPA52_RS06320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CPA52_RS06325	COG0416	fatty acid biosynthetic process
CPA52_RS06330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CPA52_RS06340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPA52_RS06345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPA52_RS06350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPA52_RS06355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CPA52_RS06360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CPA52_RS06365	COG0470	DNA polymerase III
CPA52_RS06375	COG0084	hydrolase, TatD family'
CPA52_RS06415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CPA52_RS06420	COG0527	aspartate kinase activity
CPA52_RS06430	COG0733	neurotransmitter:sodium symporter activity
CPA52_RS06440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPA52_RS06445	COG0386	Belongs to the glutathione peroxidase family
CPA52_RS06450	COG2084	Dehydrogenase
CPA52_RS06460	COG2925	Exonuclease
CPA52_RS06465	COG0582	viral genome integration into host DNA
CPA52_RS06505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CPA52_RS06545	COG1598	PFAM Uncharacterised protein family UPF0150
CPA52_RS06585	COG4695	Portal protein
CPA52_RS06705	COG0596	Alpha beta hydrolase
CPA52_RS06735	COG0583	DNA-binding transcription factor activity
CPA52_RS06745	COG2211	Major facilitator Superfamily
CPA52_RS06755	COG1472	Belongs to the glycosyl hydrolase 3 family
CPA52_RS06790	COG0300	oxidoreductase activity
CPA52_RS06795	COG3647	Membrane
CPA52_RS06815	COG3547	Transposase (IS116 IS110 IS902 family)
CPA52_RS06825	COG0653	protein targeting
CPA52_RS06840	COG2133	pyrroloquinoline quinone binding
CPA52_RS06845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CPA52_RS06845	COG0543	2 iron, 2 sulfur cluster binding
CPA52_RS06865	COG1505	serine-type exopeptidase activity
CPA52_RS06870	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CPA52_RS06890	COG2211	Major facilitator Superfamily
CPA52_RS06895	COG2723	6-phospho-beta-galactosidase activity
CPA52_RS06905	COG1472	Belongs to the glycosyl hydrolase 3 family
CPA52_RS06915	COG3706	GGDEF domain
CPA52_RS06920	COG1090	epimerase
CPA52_RS06925	COG0628	permease
CPA52_RS06955	COG2350	Protein conserved in bacteria
CPA52_RS06960	COG0733	neurotransmitter:sodium symporter activity
CPA52_RS06970	COG2917	probably involved in intracellular septation
CPA52_RS06975	COG0776	regulation of translation
CPA52_RS06980	COG0693	protein deglycase activity
CPA52_RS06995	COG0135	phosphoribosylanthranilate isomerase activity
CPA52_RS06995	COG0134	indole-3-glycerol-phosphate synthase activity
CPA52_RS07000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CPA52_RS07005	COG0512	Glutamine amidotransferase of anthranilate synthase
CPA52_RS07010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPA52_RS07015	COG0613	PHP domain protein
CPA52_RS07020	COG0009	L-threonylcarbamoyladenylate synthase
CPA52_RS07030	COG3038	cytochrome b561
CPA52_RS07035	COG2353	YceI-like domain
CPA52_RS07070	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CPA52_RS07085	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CPA52_RS07095	COG0800	Aldolase
CPA52_RS07100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPA52_RS07100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPA52_RS07105	COG0489	protein tyrosine kinase activity
CPA52_RS07110	COG0717	Belongs to the dCTP deaminase family
CPA52_RS07130	COG0436	Aminotransferase
CPA52_RS07160	COG1876	peptidase activity
CPA52_RS07165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPA52_RS07170	COG1393	Belongs to the ArsC family
CPA52_RS07175	COG2190	(PTS) system
CPA52_RS07175	COG1263	PTS System
CPA52_RS07175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPA52_RS07185	COG0280	phosphate acetyltransferase
CPA52_RS07185	COG0857	belongs to the CobB CobQ family
CPA52_RS07190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CPA52_RS07195	COG3092	negative regulation of chromosome organization
CPA52_RS07200	COG2226	methyltransferase
CPA52_RS07225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CPA52_RS07230	COG1187	pseudouridine synthase activity
CPA52_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
CPA52_RS07240	COG2267	carboxylic ester hydrolase activity
CPA52_RS07245	COG0616	signal peptide processing
CPA52_RS07250	COG1301	dicarboxylic acid transport
CPA52_RS07260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPA52_RS07270	COG2862	Uncharacterized protein family, UPF0114
CPA52_RS07275	COG0366	Alpha amylase catalytic
CPA52_RS07290	COG0366	Alpha amylase catalytic
CPA52_RS07310	COG1506	peptidase
CPA52_RS07315	COG4771	TonB-dependent receptor
CPA52_RS07320	COG1609	Transcriptional regulator
CPA52_RS07325	COG0837	glucose binding
CPA52_RS07330	COG1609	Transcriptional regulator
CPA52_RS07340	COG0800	Aldolase
CPA52_RS07345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPA52_RS07355	COG0217	transcriptional regulatory protein
CPA52_RS07360	COG3590	peptidase
CPA52_RS07365	COG5265	(ABC) transporter
CPA52_RS07375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPA52_RS07380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPA52_RS07390	COG1943	Transposase
CPA52_RS07395	COG2824	Alkylphosphonate utilization operon protein PhnA
CPA52_RS07400	COG0189	ligase activity
CPA52_RS07405	COG0456	acetyltransferase
CPA52_RS07405	COG1214	PFAM Peptidase M22, glycoprotease
CPA52_RS07410	COG1285	pathogenesis
CPA52_RS07435	COG1285	pathogenesis
CPA52_RS07455	COG0583	DNA-binding transcription factor activity
CPA52_RS07460	COG4591	ABC-type transport system involved in lipoprotein release permease component
CPA52_RS07465	COG1136	(ABC) transporter
CPA52_RS07470	COG4591	ABC-type transport system involved in lipoprotein release permease component
CPA52_RS07485	COG0318	PFAM AMP-dependent synthetase and ligase
CPA52_RS07500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CPA52_RS07505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPA52_RS07510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CPA52_RS07520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPA52_RS07525	COG1522	sequence-specific DNA binding
CPA52_RS07530	COG0659	secondary active sulfate transmembrane transporter activity
CPA52_RS07535	COG2972	Histidine kinase
CPA52_RS07540	COG3279	Response regulator of the LytR AlgR family
CPA52_RS07545	COG0469	pyruvate kinase activity
CPA52_RS07550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CPA52_RS07555	COG0252	asparaginase activity
CPA52_RS07560	COG0616	signal peptide processing
CPA52_RS07565	COG0446	pyridine nucleotide-disulphide oxidoreductase
CPA52_RS07565	COG1902	pentaerythritol trinitrate reductase activity
CPA52_RS07575	COG0778	Nitroreductase
CPA52_RS07595	COG0545	Peptidyl-prolyl cis-trans isomerase
CPA52_RS07615	COG3738	Protein conserved in bacteria
CPA52_RS07630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPA52_RS07640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CPA52_RS07650	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CPA52_RS07655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CPA52_RS07660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CPA52_RS07665	COG0539	negative regulation of cytoplasmic translation
CPA52_RS07670	COG0776	regulation of translation
CPA52_RS07680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CPA52_RS07685	COG0284	orotidine-5'-phosphate decarboxylase activity
CPA52_RS07700	COG0513	Belongs to the DEAD box helicase family
CPA52_RS07705	COG1054	Belongs to the UPF0176 family
CPA52_RS07710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPA52_RS07715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPA52_RS07720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPA52_RS07720	COG0517	IMP dehydrogenase activity
CPA52_RS07730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPA52_RS07735	COG0367	asparagine synthase
CPA52_RS07740	COG1984	allophanate hydrolase subunit 2
CPA52_RS07745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CPA52_RS07755	COG0583	DNA-binding transcription factor activity
CPA52_RS07765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CPA52_RS07775	COG4770	biotin carboxylase activity
CPA52_RS07785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CPA52_RS07790	COG1960	acyl-CoA dehydrogenase activity
CPA52_RS07800	COG0183	Belongs to the thiolase family
CPA52_RS07815	COG1024	Enoyl-CoA hydratase
CPA52_RS07820	COG1024	Enoyl-CoA hydratase
CPA52_RS07830	COG1028	Short-chain dehydrogenase reductase Sdr
CPA52_RS07880	COG3038	cytochrome b561
CPA52_RS07895	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPA52_RS07900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPA52_RS07935	COG4628	conserved protein (DUF2132)
CPA52_RS07940	COG0604	alcohol dehydrogenase
CPA52_RS07945	COG1309	transcriptional regulator
CPA52_RS07950	COG3130	regulation of translation
CPA52_RS07955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CPA52_RS07965	COG0739	heme binding
CPA52_RS07970	COG1607	acyl-coa hydrolase
CPA52_RS07975	COG2056	Na+-H+ antiporter family
CPA52_RS07990	COG0714	Associated with various cellular activities
CPA52_RS07995	COG2201	protein-glutamate methylesterase activity
CPA52_RS08015	COG0395	ABC-type sugar transport system, permease component
CPA52_RS08300	COG0281	malic enzyme
CPA52_RS08305	COG0405	Gamma-glutamyltransferase
CPA52_RS08325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CPA52_RS08330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPA52_RS08335	COG0488	(ABC) transporter
CPA52_RS08365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPA52_RS08395	COG1131	(ABC) transporter
CPA52_RS08410	COG3447	MASE1 domain protein
CPA52_RS08410	COG5001	Diguanylate cyclase
CPA52_RS08410	COG5002	protein histidine kinase activity
CPA52_RS08425	COG0183	Belongs to the thiolase family
CPA52_RS08440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPA52_RS08485	COG0501	Belongs to the peptidase M48B family
CPA52_RS08490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CPA52_RS08495	COG2226	methyltransferase
CPA52_RS08500	COG0156	8-amino-7-oxononanoate synthase activity
CPA52_RS08505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPA52_RS08510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CPA52_RS08525	COG1178	ABC-type Fe3 transport system permease component
CPA52_RS08530	COG3842	ATPase activity
CPA52_RS08545	COG0017	Asparaginyl-tRNA synthetase
CPA52_RS08575	COG1720	tRNA m6t6A37 methyltransferase activity
CPA52_RS08580	COG0442	prolyl-tRNA aminoacylation
CPA52_RS08590	COG1668	transmembrane transport
CPA52_RS08595	COG4555	ABC transporter
CPA52_RS08615	COG3152	Membrane
CPA52_RS08625	COG0022	dehydrogenase e1 component
CPA52_RS08635	COG2988	succinylglutamate desuccinylase activity
CPA52_RS08640	COG0033	Phosphoglucomutase
CPA52_RS08645	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CPA52_RS08650	COG0596	Alpha beta hydrolase
CPA52_RS08670	COG0735	belongs to the Fur family
CPA52_RS08675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPA52_RS08690	COG0045	succinate-CoA ligase (ADP-forming) activity
CPA52_RS08695	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPA52_RS08700	COG0567	Dehydrogenase, E1 component
CPA52_RS08705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPA52_RS08715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CPA52_RS08730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CPA52_RS08735	COG2166	iron-sulfur cluster assembly
CPA52_RS08740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPA52_RS08745	COG0564	pseudouridine synthase activity
CPA52_RS08750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CPA52_RS08755	COG2835	tetraacyldisaccharide 4'-kinase activity
CPA52_RS08760	COG1663	tetraacyldisaccharide 4'-kinase activity
CPA52_RS08765	COG1132	(ABC) transporter
CPA52_RS08770	COG0658	competence protein
CPA52_RS08770	COG2333	competence protein COMEC
CPA52_RS08785	COG0488	(ABC) transporter
CPA52_RS08795	COG0116	Belongs to the methyltransferase superfamily
CPA52_RS08795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CPA52_RS08805	COG0167	dihydroorotate dehydrogenase activity
CPA52_RS08810	COG2902	Dehydrogenase
CPA52_RS08840	COG0308	aminopeptidase N
CPA52_RS08845	COG1757	Na H antiporter
CPA52_RS08855	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CPA52_RS08865	COG1956	GAF domain-containing protein
CPA52_RS08900	COG0670	Belongs to the BI1 family
CPA52_RS08910	COG2923	Belongs to the DsrF TusC family
CPA52_RS08920	COG2920	part of a sulfur-relay system
CPA52_RS08925	COG1187	pseudouridine synthase activity
CPA52_RS08935	COG2203	Gaf domain
CPA52_RS08935	COG5001	Diguanylate cyclase
CPA52_RS08935	COG3706	GGDEF domain
CPA52_RS08935	COG4251	negative regulation of phosphorylation
CPA52_RS08940	COG0482	sulfurtransferase activity
CPA52_RS08945	COG2915	High frequency lysogenization protein hflD homolog
CPA52_RS08950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPA52_RS08955	COG2850	peptidyl-arginine hydroxylation
CPA52_RS08970	COG2234	aminopeptidase activity
CPA52_RS09000	COG1132	(ABC) transporter
CPA52_RS09015	COG3977	Valine--pyruvate aminotransferase
CPA52_RS09020	COG1914	H( )-stimulated, divalent metal cation uptake system
CPA52_RS09030	COG2133	pyrroloquinoline quinone binding
CPA52_RS09065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CPA52_RS09070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPA52_RS09075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CPA52_RS09080	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CPA52_RS09085	COG1674	ftsk spoiiie
CPA52_RS09085	COG0531	amino acid
CPA52_RS09095	COG0686	Belongs to the AlaDH PNT family
CPA52_RS09100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPA52_RS09105	COG0492	ferredoxin-NADP+ reductase activity
CPA52_RS09110	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CPA52_RS09115	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CPA52_RS09120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CPA52_RS09125	COG0542	response to heat
CPA52_RS09130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CPA52_RS09135	COG1278	Cold shock
CPA52_RS09150	COG1228	amidohydrolase
CPA52_RS09170	COG3001	Fructosamine kinase
CPA52_RS09180	COG0307	riboflavin synthase, alpha
CPA52_RS09205	COG3291	Pkd domain containing protein
CPA52_RS09210	COG1472	Belongs to the glycosyl hydrolase 3 family
CPA52_RS09230	COG1472	Belongs to the glycosyl hydrolase 3 family
CPA52_RS09235	COG0477	Major facilitator Superfamily
CPA52_RS09240	COG1609	Transcriptional regulator
CPA52_RS09245	COG1070	Carbohydrate kinase
CPA52_RS09250	COG2115	Belongs to the xylose isomerase family
CPA52_RS09260	COG5002	protein histidine kinase activity
CPA52_RS09260	COG2198	Histidine kinase
CPA52_RS09260	COG0784	Response regulator, receiver
CPA52_RS09280	COG2204	response regulator
CPA52_RS09290	COG1192	Involved in chromosome partitioning
CPA52_RS09310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CPA52_RS09315	COG0297	glycogen (starch) synthase activity
CPA52_RS09325	COG0438	transferase activity, transferring glycosyl groups
CPA52_RS09345	COG0438	transferase activity, transferring glycosyl groups
CPA52_RS09375	COG2146	nitrite reductase [NAD(P)H] activity
CPA52_RS09375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CPA52_RS09380	COG2146	nitrite reductase [NAD(P)H] activity
CPA52_RS09395	COG2258	MOSC domain
CPA52_RS09400	COG0314	molybdopterin synthase activity
CPA52_RS09405	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CPA52_RS09410	COG0315	cyclic pyranopterin monophosphate synthase activity
CPA52_RS09415	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPA52_RS09420	COG0746	molybdenum cofactor guanylyltransferase activity
CPA52_RS09425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CPA52_RS09430	COG0243	molybdopterin cofactor binding
CPA52_RS09435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CPA52_RS09445	COG0515	serine threonine protein kinase
CPA52_RS09445	COG2815	serine threonine protein kinase
CPA52_RS09450	COG2223	nitrite transmembrane transporter activity
CPA52_RS09455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CPA52_RS09460	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CPA52_RS09495	COG2828	Protein conserved in bacteria
CPA52_RS09500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CPA52_RS09505	COG0372	Belongs to the citrate synthase family
CPA52_RS09510	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CPA52_RS09520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPA52_RS09520	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CPA52_RS09535	COG0489	protein tyrosine kinase activity
CPA52_RS09535	COG3206	protein involved in exopolysaccharide biosynthesis
CPA52_RS09540	COG1596	polysaccharide export
CPA52_RS09560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPA52_RS09570	COG2199	diguanylate cyclase activity
CPA52_RS09570	COG2200	EAL domain
CPA52_RS09570	COG2203	Gaf domain
CPA52_RS09615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPA52_RS09655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPA52_RS09660	COG0505	Belongs to the CarA family
CPA52_RS09665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CPA52_RS09690	COG2814	Major facilitator Superfamily
CPA52_RS09695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPA52_RS09700	COG1420	regulation of RNA biosynthetic process
CPA52_RS09705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CPA52_RS09715	COG0497	DNA recombination
CPA52_RS09725	COG2199	diguanylate cyclase activity
CPA52_RS09725	COG2203	Gaf domain
CPA52_RS09730	COG0493	'glutamate synthase
CPA52_RS09735	COG0070	glutamate synthase
CPA52_RS09735	COG0067	glutamate synthase
CPA52_RS09735	COG0069	glutamate synthase activity
CPA52_RS09745	COG1136	(ABC) transporter
CPA52_RS09760	COG2204	response regulator
CPA52_RS09765	COG5002	protein histidine kinase activity
CPA52_RS09770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CPA52_RS09775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CPA52_RS09780	COG2766	serine protein kinase
CPA52_RS09785	COG2718	Belongs to the UPF0229 family
CPA52_RS09790	COG2719	SpoVR family
CPA52_RS09795	COG3706	GGDEF domain
CPA52_RS09800	COG2201	protein-glutamate methylesterase activity
CPA52_RS09805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPA52_RS09810	COG0563	adenylate kinase activity
CPA52_RS09815	COG0326	Molecular chaperone. Has ATPase activity
CPA52_RS09820	COG0564	pseudouridine synthase activity
CPA52_RS09825	COG0477	Major facilitator Superfamily
CPA52_RS09830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CPA52_RS09835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CPA52_RS09845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CPA52_RS09855	COG3219	Protein conserved in bacteria
CPA52_RS09860	COG3220	belongs to the UPF0276 family
CPA52_RS09870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPA52_RS09895	COG0848	biopolymer transport protein
CPA52_RS09900	COG0811	peptide transport
CPA52_RS09905	COG0811	peptide transport
CPA52_RS09920	COG1278	Cold shock
CPA52_RS09925	COG0418	dihydroorotase activity
CPA52_RS09935	COG0583	DNA-binding transcription factor activity
CPA52_RS09940	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CPA52_RS09950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPA52_RS09960	COG1228	amidohydrolase
CPA52_RS09965	COG3228	Belongs to the MtfA family
CPA52_RS09985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPA52_RS09995	COG1760	l-serine dehydratase
CPA52_RS10000	COG0583	DNA-binding transcription factor activity
CPA52_RS10010	COG2252	PERMEase
CPA52_RS10025	COG3012	SEC-C Motif Domain Protein
CPA52_RS10055	COG5002	protein histidine kinase activity
CPA52_RS10055	COG0784	Response regulator, receiver
CPA52_RS10055	COG2198	Histidine kinase
CPA52_RS10060	COG3437	response regulator, receiver
CPA52_RS10070	COG1418	mRNA catabolic process
CPA52_RS10075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CPA52_RS10090	COG1643	Atp-dependent helicase
CPA52_RS10105	COG0363	glucosamine-6-phosphate deaminase activity
CPA52_RS10110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CPA52_RS10115	COG0166	Belongs to the GPI family
CPA52_RS10120	COG1104	cysteine desulfurase activity
CPA52_RS10140	COG4783	chaperone-mediated protein folding
CPA52_RS10145	COG1393	Belongs to the ArsC family
CPA52_RS10165	COG2854	intermembrane phospholipid transfer
CPA52_RS10180	COG3314	Sporulation integral membrane protein YlbJ
CPA52_RS10195	COG2716	regulation of RNA biosynthetic process
CPA52_RS10200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPA52_RS10220	COG0602	queuosine metabolic process
CPA52_RS10225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CPA52_RS10250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CPA52_RS10255	COG0556	nucleotide-excision repair
CPA52_RS10260	COG0534	Mate efflux family protein
CPA52_RS10285	COG2200	EAL domain
CPA52_RS10285	COG2199	diguanylate cyclase activity
CPA52_RS10290	COG4657	Part of a membrane complex involved in electron transport
CPA52_RS10305	COG4658	electron transport chain
CPA52_RS10310	COG4659	FMN binding
CPA52_RS10315	COG4660	Part of a membrane complex involved in electron transport
CPA52_RS10320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPA52_RS10410	COG1982	Orn Lys Arg decarboxylase major
CPA52_RS10415	COG0784	Response regulator, receiver
CPA52_RS10415	COG2205	protein histidine kinase activity
CPA52_RS10425	COG1595	DNA-templated transcription, initiation
CPA52_RS10445	COG2207	Transcriptional regulator
CPA52_RS10470	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CPA52_RS10480	COG0800	Aldolase
CPA52_RS10485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPA52_RS10490	COG2271	Major facilitator Superfamily
CPA52_RS10495	COG1917	Cupin 2, conserved barrel domain protein
CPA52_RS10515	COG0346	lactoylglutathione lyase activity
CPA52_RS10520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CPA52_RS10525	COG0612	Peptidase, M16
CPA52_RS10610	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPA52_RS10625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CPA52_RS10630	COG3115	cell septum assembly
CPA52_RS10635	COG1196	nuclear chromosome segregation
CPA52_RS10640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPA52_RS10665	COG1166	arginine decarboxylase activity
CPA52_RS10685	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CPA52_RS10690	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CPA52_RS10695	COG2363	Small membrane protein
CPA52_RS10705	COG0583	DNA-binding transcription factor activity
CPA52_RS10710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CPA52_RS10715	COG5505	Protein of unknown function (DUF819)
CPA52_RS10730	COG0784	Response regulator, receiver
CPA52_RS10730	COG3437	response regulator, receiver
CPA52_RS10740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CPA52_RS10745	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CPA52_RS10750	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CPA52_RS10755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CPA52_RS10765	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CPA52_RS10770	COG0193	aminoacyl-tRNA hydrolase activity
CPA52_RS10775	COG0012	GTP binding
CPA52_RS10835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CPA52_RS10840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPA52_RS10845	COG1702	phosphate starvation-inducible protein PhoH
CPA52_RS10850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CPA52_RS10855	COG4535	Mg2 and Co2 transporter CorC
CPA52_RS10860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CPA52_RS10895	COG0545	Peptidyl-prolyl cis-trans isomerase
CPA52_RS10900	COG1067	ATP-dependent peptidase activity
CPA52_RS10905	COG2888	peptidyl-tyrosine sulfation
CPA52_RS10910	COG0495	leucyl-tRNA aminoacylation
CPA52_RS10925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CPA52_RS10930	COG0799	negative regulation of ribosome biogenesis
CPA52_RS10935	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CPA52_RS10940	COG0768	penicillin binding
CPA52_RS10945	COG0772	Belongs to the SEDS family
CPA52_RS10950	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPA52_RS10955	COG1686	Belongs to the peptidase S11 family
CPA52_RS10960	COG2921	Belongs to the UPF0250 family
CPA52_RS10965	COG0321	lipoyl(octanoyl) transferase activity
CPA52_RS10970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CPA52_RS10980	COG0724	RNA recognition motif
CPA52_RS10990	COG1320	monovalent cation:proton antiporter activity
CPA52_RS10995	COG2212	antiporter activity
CPA52_RS11000	COG1863	multisubunit Na H antiporter MnhE subunit
CPA52_RS11005	COG0651	ATP synthesis coupled electron transport
CPA52_RS11010	COG1006	Multisubunit Na H antiporter MnhC subunit
CPA52_RS11015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPA52_RS11015	COG2111	Na H antiporter
CPA52_RS11030	COG1185	polyribonucleotide nucleotidyltransferase activity
CPA52_RS11035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CPA52_RS11040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CPA52_RS11045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CPA52_RS11050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CPA52_RS11055	COG0195	Participates in both transcription termination and antitermination
CPA52_RS11060	COG0779	Required for maturation of 30S ribosomal subunits
CPA52_RS11075	COG3046	protein related to deoxyribodipyrimidine photolyase
CPA52_RS11105	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CPA52_RS11120	COG3101	peptidyl-lysine hydroxylation
CPA52_RS11135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CPA52_RS11140	COG2890	protein-(glutamine-N5) methyltransferase activity
CPA52_RS11145	COG2840	Smr protein MutS2
CPA52_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
CPA52_RS11160	COG0251	oxidation-reduction process
CPA52_RS11165	COG2062	phosphohistidine phosphatase, SixA
CPA52_RS11170	COG1025	Belongs to the peptidase M16 family
CPA52_RS11175	COG3300	MHYT domain
CPA52_RS11175	COG5001	Diguanylate cyclase
CPA52_RS11185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPA52_RS11190	COG2315	Protein conserved in bacteria
CPA52_RS11195	COG1024	Enoyl-CoA hydratase
CPA52_RS11195	COG1250	3-hydroxyacyl-CoA dehydrogenase
CPA52_RS11200	COG0183	Belongs to the thiolase family
CPA52_RS11205	COG0714	Associated with various cellular activities
CPA52_RS11225	COG2304	oxidoreductase activity
CPA52_RS11235	COG1595	DNA-templated transcription, initiation
CPA52_RS11260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPA52_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CPA52_RS11265	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CPA52_RS11275	COG0702	epimerase
CPA52_RS11295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CPA52_RS11310	COG0814	amino acid
CPA52_RS11315	COG1448	Aminotransferase
CPA52_RS11335	COG0023	Translation Initiation Factor
CPA52_RS11345	COG1605	Chorismate mutase
CPA52_RS11345	COG0077	Prephenate dehydratase
CPA52_RS11350	COG1605	Chorismate mutase
CPA52_RS11350	COG0287	Prephenate dehydrogenase
CPA52_RS11355	COG0335	large ribosomal subunit rRNA binding
CPA52_RS11360	COG0336	Belongs to the RNA methyltransferase TrmD family
CPA52_RS11365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CPA52_RS11370	COG0228	four-way junction DNA binding
CPA52_RS11375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPA52_RS11380	COG4137	Cytochrome C assembly protein
CPA52_RS11385	COG4536	flavin adenine dinucleotide binding
CPA52_RS11395	COG2918	glutathione biosynthetic process
CPA52_RS11405	COG0542	response to heat
CPA52_RS11415	COG0564	pseudouridine synthase activity
CPA52_RS11420	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CPA52_RS11440	COG4968	Prepilin-type N-terminal cleavage methylation domain
CPA52_RS11470	COG2972	Histidine kinase
CPA52_RS11470	COG0745	RESPONSE REGULATOR receiver
CPA52_RS11475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CPA52_RS11480	COG1047	Peptidyl-prolyl cis-trans
CPA52_RS11485	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPA52_RS11490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CPA52_RS11495	COG0196	riboflavin kinase activity
CPA52_RS11500	COG0728	peptidoglycan biosynthetic process
CPA52_RS11505	COG0268	Binds directly to 16S ribosomal RNA
CPA52_RS11510	COG2201	protein-glutamate methylesterase activity
CPA52_RS11525	COG2840	Smr protein MutS2
CPA52_RS11530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPA52_RS11545	COG3047	cAMP biosynthetic process
CPA52_RS11555	COG0835	chemotaxis
CPA52_RS11565	COG1192	Involved in chromosome partitioning
CPA52_RS11570	COG1360	Flagellar Motor Protein
CPA52_RS11575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CPA52_RS11580	COG2201	protein-glutamate methylesterase activity
CPA52_RS11585	COG2198	Histidine kinase
CPA52_RS11585	COG0784	Response regulator, receiver
CPA52_RS11585	COG0643	Histidine kinase
CPA52_RS11590	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CPA52_RS11615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPA52_RS11620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPA52_RS11640	COG3190	flagellar
CPA52_RS11660	COG3144	bacterial-type flagellum assembly
CPA52_RS11680	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPA52_RS11690	COG1677	Flagellar hook-basal body complex protein FliE
CPA52_RS11705	COG0519	Catalyzes the synthesis of GMP from XMP
CPA52_RS11715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CPA52_RS11725	COG1083	cytidylyl-transferase
CPA52_RS11745	COG2089	acid synthase
CPA52_RS11750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CPA52_RS11755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CPA52_RS11775	COG1516	flagellar protein fliS
CPA52_RS11790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CPA52_RS11815	COG1705	Flagellar rod assembly protein muramidase FlgJ
CPA52_RS11815	COG3951	Flagellar rod assembly protein muramidase FlgJ
CPA52_RS11820	COG1706	bacterial-type flagellum-dependent cell motility
CPA52_RS11825	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CPA52_RS11830	COG4786	Flagellar basal body rod
CPA52_RS11835	COG4787	bacterial-type flagellum-dependent cell motility
CPA52_RS11855	COG1815	bacterial-type flagellum-dependent cell motility
CPA52_RS11860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CPA52_RS11865	COG0784	Response regulator, receiver
CPA52_RS11865	COG0835	chemotaxis
CPA52_RS11900	COG0678	peroxiredoxin activity
CPA52_RS11900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPA52_RS11915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CPA52_RS11955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPA52_RS11960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CPA52_RS11965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CPA52_RS11970	COG0730	response to heat
CPA52_RS11975	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CPA52_RS11980	COG1051	belongs to the nudix hydrolase family
CPA52_RS11985	COG3066	DNA modification
CPA52_RS12000	COG0148	phosphopyruvate hydratase activity
CPA52_RS12005	COG0504	CTP synthase activity
CPA52_RS12010	COG3956	TIGRFAM MazG family protein
CPA52_RS12015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPA52_RS12020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPA52_RS12025	COG4999	Histidine kinase
CPA52_RS12025	COG2205	protein histidine kinase activity
CPA52_RS12025	COG3437	response regulator, receiver
CPA52_RS12025	COG3850	Histidine kinase
CPA52_RS12030	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CPA52_RS12035	COG1381	Involved in DNA repair and RecF pathway recombination
CPA52_RS12045	COG0571	ribonuclease III activity
CPA52_RS12055	COG0481	GTPase activity
CPA52_RS12075	COG1595	DNA-templated transcription, initiation
CPA52_RS12080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CPA52_RS12090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CPA52_RS12095	COG0354	folic acid binding
CPA52_RS12100	COG1047	Peptidyl-prolyl cis-trans
CPA52_RS12115	COG3099	Belongs to the UPF0263 family
CPA52_RS12120	COG1024	Enoyl-CoA hydratase
CPA52_RS12120	COG1250	3-hydroxyacyl-CoA dehydrogenase
CPA52_RS12130	COG1346	cytolysis
CPA52_RS12135	COG0668	transmembrane transport
CPA52_RS12140	COG4249	Peptidase C14 caspase catalytic subunit p20
CPA52_RS12140	COG2319	Wd-40 repeat
CPA52_RS12150	COG5001	Diguanylate cyclase
CPA52_RS12150	COG4251	negative regulation of phosphorylation
CPA52_RS12150	COG3706	GGDEF domain
CPA52_RS12150	COG2203	Gaf domain
CPA52_RS12180	COG0438	transferase activity, transferring glycosyl groups
CPA52_RS12195	COG0793	Belongs to the peptidase S41A family
CPA52_RS12210	COG0788	formyltetrahydrofolate deformylase activity
CPA52_RS12215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CPA52_RS12225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CPA52_RS12235	COG4773	Receptor
CPA52_RS12250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CPA52_RS12255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPA52_RS12260	COG4942	peptidase
CPA52_RS12260	COG1388	LysM domain
CPA52_RS12270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CPA52_RS12275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CPA52_RS12280	COG0585	pseudouridine synthase activity
CPA52_RS12285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CPA52_RS12290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CPA52_RS12295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CPA52_RS12340	COG0454	-acetyltransferase
CPA52_RS12355	COG3123	guanosine phosphorylase activity
CPA52_RS12360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPA52_RS12365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CPA52_RS12375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CPA52_RS12380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CPA52_RS12385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPA52_RS12405	COG0560	Phosphoserine phosphatase
CPA52_RS12415	COG0084	hydrolase, TatD family'
CPA52_RS12420	COG0259	pyridoxamine-phosphate oxidase activity
CPA52_RS12425	COG0018	arginyl-trna synthetase
CPA52_RS12430	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CPA52_RS12435	COG0784	Response regulator, receiver
CPA52_RS12435	COG2205	protein histidine kinase activity
CPA52_RS12440	COG0456	acetyltransferase
CPA52_RS12455	COG0519	Catalyzes the synthesis of GMP from XMP
CPA52_RS12455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CPA52_RS12460	COG0516	GMP reductase activity
CPA52_RS12460	COG0517	IMP dehydrogenase activity
CPA52_RS12465	COG1570	exodeoxyribonuclease VII activity
CPA52_RS12475	COG1045	serine acetyltransferase
CPA52_RS12480	COG5001	Diguanylate cyclase
CPA52_RS12480	COG4251	negative regulation of phosphorylation
CPA52_RS12480	COG3706	GGDEF domain
CPA52_RS12480	COG2203	Gaf domain
CPA52_RS12495	COG0612	Peptidase, M16
CPA52_RS12515	COG0513	Belongs to the DEAD box helicase family
CPA52_RS12530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPA52_RS12540	COG3706	GGDEF domain
CPA52_RS12545	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CPA52_RS12570	COG0745	RESPONSE REGULATOR receiver
CPA52_RS12575	COG0642	Histidine kinase
CPA52_RS12605	COG0617	tRNA 3'-terminal CCA addition
CPA52_RS12620	COG2204	response regulator
CPA52_RS12630	COG2205	protein histidine kinase activity
CPA52_RS12675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPA52_RS12680	COG1489	DNA binding
CPA52_RS12700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPA52_RS12705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CPA52_RS12710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CPA52_RS12725	COG5002	protein histidine kinase activity
CPA52_RS12730	COG0745	RESPONSE REGULATOR receiver
CPA52_RS12740	COG0126	phosphoglycerate kinase activity
CPA52_RS12745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPA52_RS12770	COG0516	GMP reductase activity
CPA52_RS12770	COG0517	IMP dehydrogenase activity
CPA52_RS12775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPA52_RS12785	COG2205	protein histidine kinase activity
CPA52_RS12785	COG0784	Response regulator, receiver
CPA52_RS12800	COG3706	GGDEF domain
CPA52_RS12840	COG3250	beta-galactosidase activity
CPA52_RS12845	COG1979	alcohol dehydrogenase
CPA52_RS12850	COG2207	Transcriptional regulator
CPA52_RS12855	COG3300	MHYT domain
CPA52_RS12855	COG5001	Diguanylate cyclase
CPA52_RS12875	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CPA52_RS12940	COG1858	cytochrome C peroxidase
CPA52_RS12945	COG0840	transmembrane signaling receptor activity
CPA52_RS12945	COG5278	phosphoserine phosphatase activity
CPA52_RS12965	COG0783	Belongs to the Dps family
CPA52_RS12980	COG1595	DNA-templated transcription, initiation
CPA52_RS12990	COG2205	protein histidine kinase activity
CPA52_RS12990	COG0784	Response regulator, receiver
CPA52_RS12995	COG0604	alcohol dehydrogenase
CPA52_RS13000	COG0583	DNA-binding transcription factor activity
CPA52_RS13010	COG1024	Enoyl-CoA hydratase
CPA52_RS13020	COG0840	transmembrane signaling receptor activity
CPA52_RS13040	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CPA52_RS13090	COG3657	addiction module killer protein
CPA52_RS13110	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPA52_RS13110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPA52_RS13115	COG0509	glycine decarboxylation via glycine cleavage system
CPA52_RS13120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CPA52_RS13130	COG0583	DNA-binding transcription factor activity
CPA52_RS13135	COG4774	siderophore transport
CPA52_RS13140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPA52_RS13145	COG0557	exoribonuclease II activity
CPA52_RS13150	COG1024	Enoyl-CoA hydratase
CPA52_RS13155	COG2197	response regulator
CPA52_RS13160	COG4585	Histidine kinase
CPA52_RS13170	COG0584	glycerophosphoryl diester phosphodiesterase
CPA52_RS13175	COG0840	transmembrane signaling receptor activity
CPA52_RS13180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CPA52_RS13190	COG2202	Pas domain
CPA52_RS13190	COG2205	protein histidine kinase activity
CPA52_RS13195	COG1247	-acetyltransferase
CPA52_RS13210	COG0625	glutathione transferase activity
CPA52_RS13240	COG3954	Phosphoribulokinase
CPA52_RS13245	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CPA52_RS13250	COG1011	Hydrolase
CPA52_RS13255	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CPA52_RS13260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPA52_RS13265	COG0849	cell division
CPA52_RS13270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CPA52_RS13275	COG1181	Belongs to the D-alanine--D-alanine ligase family
CPA52_RS13280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPA52_RS13285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPA52_RS13290	COG0772	Belongs to the SEDS family
CPA52_RS13295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPA52_RS13300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPA52_RS13305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CPA52_RS13310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPA52_RS13315	COG0768	penicillin binding
CPA52_RS13320	COG3116	cell division
CPA52_RS13325	COG0275	rRNA processing
CPA52_RS13330	COG2001	Belongs to the MraZ family
CPA52_RS13350	COG0435	Glutathione S-transferase
CPA52_RS13355	COG1741	Belongs to the pirin family
CPA52_RS13370	COG1295	ribonuclease BN
CPA52_RS13385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPA52_RS13395	COG0792	nuclease activity
CPA52_RS13405	COG2823	Periplasmic or secreted lipoprotein
CPA52_RS13410	COG2969	positive regulation of protein catabolic process
CPA52_RS13415	COG0625	glutathione transferase activity
CPA52_RS13420	COG2857	Cytochrome c1
CPA52_RS13425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CPA52_RS13430	COG0723	plastoquinol--plastocyanin reductase activity
CPA52_RS13435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CPA52_RS13440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CPA52_RS13445	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CPA52_RS13455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPA52_RS13465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPA52_RS13470	COG5007	Belongs to the BolA IbaG family
CPA52_RS13475	COG3113	response to antibiotic
CPA52_RS13480	COG2854	intermembrane phospholipid transfer
CPA52_RS13485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CPA52_RS13490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CPA52_RS13495	COG1127	ABC transporter
CPA52_RS13505	COG0517	IMP dehydrogenase activity
CPA52_RS13505	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPA52_RS13510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CPA52_RS13525	COG1137	ATPase activity
CPA52_RS13530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CPA52_RS13545	COG1660	Displays ATPase and GTPase activities
CPA52_RS13550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPA52_RS13555	COG2239	Acts as a magnesium transporter
CPA52_RS13560	COG1032	radical SAM domain protein
CPA52_RS13565	COG3300	MHYT domain
CPA52_RS13565	COG5001	Diguanylate cyclase
CPA52_RS13605	COG1842	Phage shock protein A
CPA52_RS13615	COG2095	MarC family integral membrane protein
CPA52_RS13620	COG0735	belongs to the Fur family
CPA52_RS13630	COG0432	Pfam Uncharacterised protein family UPF0047
CPA52_RS13650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CPA52_RS13655	COG1162	GTPase activity
CPA52_RS13660	COG0688	phosphatidylethanolamine metabolic process
CPA52_RS13665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CPA52_RS13675	COG2022	thiamine diphosphate biosynthetic process
CPA52_RS13690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CPA52_RS13705	COG1629	transport
CPA52_RS13705	COG4774	siderophore transport
CPA52_RS13710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CPA52_RS13715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPA52_RS13740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CPA52_RS13745	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CPA52_RS13750	COG1187	pseudouridine synthase activity
CPA52_RS13765	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CPA52_RS13780	COG2897	thiosulfate sulfurtransferase activity
CPA52_RS13785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CPA52_RS13805	COG5001	Diguanylate cyclase
CPA52_RS13805	COG3300	MHYT domain
CPA52_RS13815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CPA52_RS13825	COG4181	ATPase activity
CPA52_RS13845	COG0678	peroxiredoxin activity
CPA52_RS13845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CPA52_RS13865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPA52_RS13875	COG0529	Catalyzes the synthesis of activated sulfate
CPA52_RS13880	COG3273	potassium ion transport
CPA52_RS13880	COG0471	metal ion transport
CPA52_RS13890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CPA52_RS13940	COG1216	Glycosyl transferase, family 2
CPA52_RS13950	COG2895	sulfate adenylyltransferase (ATP) activity
CPA52_RS13960	COG0175	sulfate reduction
CPA52_RS13970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CPA52_RS13975	COG1596	polysaccharide export
CPA52_RS13985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CPA52_RS14020	COG1086	Polysaccharide biosynthesis protein
CPA52_RS14085	COG3137	Salt-induced outer membrane protein
CPA52_RS14090	COG0668	transmembrane transport
CPA52_RS14125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CPA52_RS14140	COG0443	Heat shock 70 kDa protein
CPA52_RS14145	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CPA52_RS14155	COG0822	iron-sulfur transferase activity
CPA52_RS14160	COG1104	cysteine desulfurase activity
CPA52_RS14170	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CPA52_RS14175	COG0742	ribosomal rna small subunit methyltransferase
CPA52_RS14185	COG0339	signal peptide processing
CPA52_RS14190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPA52_RS14195	COG0668	transmembrane transport
CPA52_RS14200	COG0312	modulator of DNA gyrase
CPA52_RS14205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPA52_RS14210	COG3164	Protein of unknown function
CPA52_RS14215	COG1530	ribonuclease E activity
CPA52_RS14220	COG0424	maF-like protein
CPA52_RS14225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CPA52_RS14230	COG1792	Involved in formation and maintenance of cell shape
CPA52_RS14235	COG1077	Cell shape determining protein MreB Mrl
CPA52_RS14240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CPA52_RS14250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CPA52_RS14260	COG0629	single-stranded DNA binding
CPA52_RS14265	COG2814	Major facilitator Superfamily
CPA52_RS14270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CPA52_RS14275	COG0745	RESPONSE REGULATOR receiver
CPA52_RS14295	COG0180	Tryptophanyl-tRNA synthetase
CPA52_RS14305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPA52_RS14320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CPA52_RS14330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CPA52_RS14335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPA52_RS14365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CPA52_RS14370	COG0527	aspartate kinase activity
CPA52_RS14370	COG0460	homoserine dehydrogenase
CPA52_RS14375	COG0626	cystathionine gamma-synthase activity
CPA52_RS14380	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CPA52_RS14385	COG0281	malic enzyme
CPA52_RS14390	COG0254	rRNA binding
CPA52_RS14395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPA52_RS14400	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CPA52_RS14405	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CPA52_RS14410	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CPA52_RS14430	COG0671	phosphoesterase, PA-phosphatase related
CPA52_RS14435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CPA52_RS14450	COG1228	amidohydrolase
CPA52_RS14460	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CPA52_RS14470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPA52_RS14475	COG0653	protein targeting
CPA52_RS14490	COG3590	peptidase
CPA52_RS14500	COG0312	modulator of DNA gyrase
CPA52_RS14520	COG3078	GTPase activator activity
CPA52_RS14530	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CPA52_RS14545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPA52_RS14545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPA52_RS14550	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CPA52_RS14570	COG2960	long-chain fatty acid transporting porin activity
CPA52_RS14580	COG0288	reversible hydration of carbon dioxide
CPA52_RS14595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPA52_RS14600	COG0129	dihydroxy-acid dehydratase activity
CPA52_RS14620	COG2205	protein histidine kinase activity
CPA52_RS14620	COG0784	Response regulator, receiver
CPA52_RS14660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPA52_RS14665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CPA52_RS14670	COG1561	YicC-like family, N-terminal region
CPA52_RS14675	COG0194	GDP metabolic process
CPA52_RS14680	COG1758	RNA polymerase activity
CPA52_RS14685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPA52_RS14700	COG2502	aspartate--ammonia ligase
CPA52_RS14705	COG1522	sequence-specific DNA binding
CPA52_RS14710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPA52_RS14715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CPA52_RS14745	COG0724	RNA recognition motif
CPA52_RS14750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CPA52_RS14760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPA52_RS14765	COG1683	Conserved Protein
CPA52_RS14775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CPA52_RS14780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CPA52_RS14820	COG3156	type II secretion system protein K
CPA52_RS14830	COG2165	general secretion pathway protein
CPA52_RS14840	COG2165	general secretion pathway protein
CPA52_RS14845	COG1459	type II secretion system
CPA52_RS14850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPA52_RS14860	COG3031	protein transport across the cell outer membrane
CPA52_RS14870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CPA52_RS14875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CPA52_RS14895	COG0203	ribosomal protein L17
CPA52_RS14900	COG0202	RNA polymerase activity
CPA52_RS14905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CPA52_RS14910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CPA52_RS14915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPA52_RS14920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CPA52_RS14925	COG0201	protein transport
CPA52_RS14930	COG0200	Binds to the 23S rRNA
CPA52_RS14935	COG1841	ribosomal large subunit assembly
CPA52_RS14940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CPA52_RS14945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CPA52_RS14950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CPA52_RS14955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CPA52_RS14960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CPA52_RS14965	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CPA52_RS14970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CPA52_RS14975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CPA52_RS15015	COG1136	(ABC) transporter
CPA52_RS15020	COG0577	efflux transmembrane transporter activity
CPA52_RS15040	COG4555	ABC transporter
CPA52_RS15050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPA52_RS15060	COG0640	Transcriptional regulator
CPA52_RS15110	COG1132	(ABC) transporter
CPA52_RS15115	COG2885	chlorophyll binding
CPA52_RS15125	COG0668	transmembrane transport
CPA52_RS15130	COG0204	Acyl-transferase
CPA52_RS15135	COG0204	Acyl-transferase
CPA52_RS15140	COG1166	arginine decarboxylase activity
CPA52_RS15145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CPA52_RS15165	COG1082	Xylose isomerase domain protein TIM barrel
CPA52_RS15180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CPA52_RS15195	COG2183	response to ionizing radiation
CPA52_RS15210	COG0596	Alpha beta hydrolase
CPA52_RS15215	COG1040	competence protein
CPA52_RS15225	COG0316	Belongs to the HesB IscA family
CPA52_RS15225	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CPA52_RS15235	COG0534	Mate efflux family protein
CPA52_RS15240	COG0726	polysaccharide deacetylase
CPA52_RS15245	COG2201	protein-glutamate methylesterase activity
CPA52_RS15250	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CPA52_RS15255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CPA52_RS15265	COG0835	chemotaxis
CPA52_RS15270	COG0643	Histidine kinase
CPA52_RS15270	COG2198	Histidine kinase
CPA52_RS15275	COG0745	RESPONSE REGULATOR receiver
CPA52_RS15285	COG1999	signal sequence binding
CPA52_RS15290	COG0109	protoheme IX farnesyltransferase activity
CPA52_RS15295	COG1612	heme a metabolic process
CPA52_RS15320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CPA52_RS15325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CPA52_RS15375	COG0431	NADPH-dependent FMN reductase
CPA52_RS15400	COG0066	3-isopropylmalate dehydratase activity
CPA52_RS15405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CPA52_RS15410	COG0473	3-isopropylmalate dehydrogenase activity
CPA52_RS15415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPA52_RS15430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPA52_RS15435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CPA52_RS15440	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CPA52_RS15445	COG0545	Peptidyl-prolyl cis-trans isomerase
CPA52_RS15455	COG2900	Belongs to the SlyX family
CPA52_RS15460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CPA52_RS15465	COG0488	(ABC) transporter
CPA52_RS15475	COG0429	hydrolase of the alpha beta-hydrolase fold
CPA52_RS15480	COG3089	Belongs to the UPF0270 family
CPA52_RS15490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPA52_RS15515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CPA52_RS15525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CPA52_RS15540	COG0537	adenosine 5'-monophosphoramidase activity
CPA52_RS15565	COG0436	Aminotransferase
CPA52_RS15570	COG0069	glutamate synthase activity
CPA52_RS15580	COG2199	diguanylate cyclase activity
CPA52_RS15585	COG2226	methyltransferase
CPA52_RS15600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPA52_RS15605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPA52_RS15610	COG0805	protein transport
CPA52_RS15620	COG0084	hydrolase, TatD family'
CPA52_RS15625	COG3706	GGDEF domain
CPA52_RS15625	COG4251	negative regulation of phosphorylation
CPA52_RS15625	COG5001	Diguanylate cyclase
CPA52_RS15625	COG2203	Gaf domain
CPA52_RS15640	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CPA52_RS15645	COG2943	transferase activity, transferring hexosyl groups
CPA52_RS15645	COG3416	Protein conserved in bacteria
CPA52_RS15650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPA52_RS15665	COG4681	YaeQ
CPA52_RS15680	COG0783	Belongs to the Dps family
CPA52_RS15685	COG1770	oligopeptidase
CPA52_RS15690	COG3397	chitin binding
CPA52_RS15700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CPA52_RS15710	COG0386	Belongs to the glutathione peroxidase family
CPA52_RS15740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CPA52_RS15755	COG0784	Response regulator, receiver
CPA52_RS15755	COG2205	protein histidine kinase activity
CPA52_RS15820	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CPA52_RS15860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CPA52_RS15870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPA52_RS15875	COG2346	COG2346, Truncated hemoglobins
CPA52_RS15880	COG0408	coproporphyrinogen oxidase activity
CPA52_RS15885	COG0009	L-threonylcarbamoyladenylate synthase
CPA52_RS15895	COG2922	Belongs to the Smg family
CPA52_RS15900	COG0758	DNA mediated transformation
CPA52_RS15910	COG0242	peptide deformylase activity
CPA52_RS15915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPA52_RS15920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPA52_RS15920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPA52_RS15925	COG0569	domain protein
CPA52_RS15950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPA52_RS15955	COG1739	Uncharacterized protein family UPF0029
CPA52_RS15960	COG0006	proline dipeptidase activity
CPA52_RS15965	COG0741	lytic transglycosylase activity
CPA52_RS15970	COG1024	Enoyl-CoA hydratase
CPA52_RS15970	COG1250	3-hydroxyacyl-CoA dehydrogenase
CPA52_RS15975	COG0183	Belongs to the thiolase family
CPA52_RS15980	COG0425	Belongs to the sulfur carrier protein TusA family
CPA52_RS15990	COG0751	glycine-tRNA ligase activity
CPA52_RS15995	COG0752	glycyl-tRNA synthetase alpha subunit
CPA52_RS16000	COG0187	DNA topoisomerase II activity
CPA52_RS16005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP