locus-tag	class	description
D0N37_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D0N37_RS00020	COG0187	DNA topoisomerase II activity
D0N37_RS00025	COG0752	glycyl-tRNA synthetase alpha subunit
D0N37_RS00030	COG0751	glycine-tRNA ligase activity
D0N37_RS00040	COG0425	Belongs to the sulfur carrier protein TusA family
D0N37_RS00045	COG0183	Belongs to the thiolase family
D0N37_RS00050	COG1024	Enoyl-CoA hydratase
D0N37_RS00050	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0N37_RS00060	COG0006	proline dipeptidase activity
D0N37_RS00085	COG0569	domain protein
D0N37_RS00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0N37_RS00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0N37_RS00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D0N37_RS00100	COG0242	peptide deformylase activity
D0N37_RS00110	COG0758	DNA mediated transformation
D0N37_RS00115	COG2922	Belongs to the Smg family
D0N37_RS00120	COG0551	DNA topoisomerase type I activity
D0N37_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
D0N37_RS00130	COG0408	coproporphyrinogen oxidase activity
D0N37_RS00145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0N37_RS00155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D0N37_RS00230	COG1522	sequence-specific DNA binding
D0N37_RS00240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0N37_RS00270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0N37_RS00310	COG0302	gtp cyclohydrolase
D0N37_RS00320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D0N37_RS00325	COG3132	Protein of unknown function, DUF480
D0N37_RS00345	COG3153	acetyltransferase
D0N37_RS00345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0N37_RS00350	COG2076	Multidrug Resistance protein
D0N37_RS00365	COG1187	pseudouridine synthase activity
D0N37_RS00390	COG1011	Hydrolase
D0N37_RS00405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D0N37_RS00410	COG0019	diaminopimelate decarboxylase activity
D0N37_RS00420	COG1965	Belongs to the frataxin family
D0N37_RS00425	COG0400	carboxylic ester hydrolase activity
D0N37_RS00435	COG0181	hydroxymethylbilane synthase activity
D0N37_RS00450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D0N37_RS00455	COG0617	tRNA 3'-terminal CCA addition
D0N37_RS00455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0N37_RS00455	COG0517	IMP dehydrogenase activity
D0N37_RS00465	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D0N37_RS00485	COG0513	Belongs to the DEAD box helicase family
D0N37_RS00515	COG3118	belongs to the thioredoxin family
D0N37_RS00525	COG0248	Ppx GppA phosphatase
D0N37_RS00550	COG4771	TonB-dependent receptor
D0N37_RS00565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0N37_RS00580	COG1082	Xylose isomerase domain protein TIM barrel
D0N37_RS00595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0N37_RS00610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0N37_RS00615	COG0473	3-isopropylmalate dehydrogenase activity
D0N37_RS00620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D0N37_RS00625	COG0066	3-isopropylmalate dehydratase activity
D0N37_RS00645	COG1595	DNA-templated transcription, initiation
D0N37_RS00655	COG3433	isochorismatase activity
D0N37_RS00655	COG1535	isochorismatase
D0N37_RS00660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0N37_RS00665	COG2375	cellular response to nickel ion
D0N37_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS00675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0N37_RS00680	COG0402	S-adenosylhomocysteine deaminase activity
D0N37_RS00695	COG1629	transport
D0N37_RS00710	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D0N37_RS00715	COG1132	(ABC) transporter
D0N37_RS00725	COG1049	propionate catabolic process, 2-methylcitrate cycle
D0N37_RS00735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0N37_RS00755	COG3852	Histidine kinase
D0N37_RS00770	COG0174	glutamine synthetase
D0N37_RS00780	COG1136	(ABC) transporter
D0N37_RS00805	COG1217	gtp-binding protein TYPA
D0N37_RS00820	COG1444	tRNA N-acetyltransferase activity
D0N37_RS00825	COG0210	DNA helicase
D0N37_RS00830	COG0835	chemotaxis
D0N37_RS00830	COG0784	Response regulator, receiver
D0N37_RS00850	COG1946	Acyl-CoA thioesterase
D0N37_RS00910	COG1011	Hydrolase
D0N37_RS00915	COG0494	nUDIX hydrolase
D0N37_RS00920	COG1218	3'(2'),5'-bisphosphate nucleotidase
D0N37_RS00940	COG0840	transmembrane signaling receptor activity
D0N37_RS00960	COG3275	phosphorelay sensor kinase activity
D0N37_RS00965	COG3279	Response regulator of the LytR AlgR family
D0N37_RS00985	COG0488	(ABC) transporter
D0N37_RS00990	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D0N37_RS00995	COG2900	Belongs to the SlyX family
D0N37_RS01005	COG0545	Peptidyl-prolyl cis-trans isomerase
D0N37_RS01010	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
D0N37_RS01015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D0N37_RS01025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D0N37_RS01060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0N37_RS01070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D0N37_RS01080	COG0051	transcription antitermination factor activity, RNA binding
D0N37_RS01090	COG0088	Forms part of the polypeptide exit tunnel
D0N37_RS01095	COG0089	rRNA binding
D0N37_RS01100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D0N37_RS01105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D0N37_RS01110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D0N37_RS01115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D0N37_RS01120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D0N37_RS01125	COG0255	Belongs to the universal ribosomal protein uL29 family
D0N37_RS01130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0N37_RS01135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0N37_RS01140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0N37_RS01145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0N37_RS01150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0N37_RS01160	COG0840	transmembrane signaling receptor activity
D0N37_RS01165	COG0784	Response regulator, receiver
D0N37_RS01165	COG2205	protein histidine kinase activity
D0N37_RS01180	COG2610	gluconate transmembrane transporter activity
D0N37_RS01185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D0N37_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS01195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0N37_RS01200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0N37_RS01225	COG0596	Alpha beta hydrolase
D0N37_RS01230	COG1490	D-aminoacyl-tRNA deacylase activity
D0N37_RS01245	COG0456	acetyltransferase
D0N37_RS01260	COG0019	diaminopimelate decarboxylase activity
D0N37_RS01270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0N37_RS01275	COG0784	Response regulator, receiver
D0N37_RS01275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS01275	COG2198	Histidine kinase
D0N37_RS01275	COG2205	protein histidine kinase activity
D0N37_RS01305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0N37_RS01310	COG0129	dihydroxy-acid dehydratase activity
D0N37_RS01315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D0N37_RS01335	COG0288	reversible hydration of carbon dioxide
D0N37_RS01360	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D0N37_RS01365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0N37_RS01365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0N37_RS01380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D0N37_RS01410	COG0431	NADPH-dependent FMN reductase
D0N37_RS01450	COG2356	endonuclease I
D0N37_RS01455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0N37_RS01460	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0N37_RS01490	COG2050	protein possibly involved in aromatic compounds catabolism
D0N37_RS01530	COG1218	3'(2'),5'-bisphosphate nucleotidase
D0N37_RS01540	COG3273	potassium ion transport
D0N37_RS01540	COG0471	metal ion transport
D0N37_RS01545	COG2895	sulfate adenylyltransferase (ATP) activity
D0N37_RS01550	COG0175	sulfate reduction
D0N37_RS01570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0N37_RS01585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0N37_RS01590	COG0250	Participates in transcription elongation, termination and antitermination
D0N37_RS01595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D0N37_RS01605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D0N37_RS01610	COG0222	ribosome binding
D0N37_RS01615	COG0085	RNA polymerase activity
D0N37_RS01620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D0N37_RS01625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D0N37_RS01630	COG0049	tRNA binding
D0N37_RS01635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0N37_RS01640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0N37_RS01690	COG0823	Involved in the tonB-independent uptake of proteins
D0N37_RS01690	COG1506	peptidase
D0N37_RS01695	COG1253	flavin adenine dinucleotide binding
D0N37_RS01700	COG2202	Pas domain
D0N37_RS01700	COG2200	EAL domain
D0N37_RS01700	COG2199	diguanylate cyclase activity
D0N37_RS01710	COG2031	fatty acid transporter
D0N37_RS01720	COG0679	Auxin Efflux Carrier
D0N37_RS01745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0N37_RS01755	COG2814	Major facilitator Superfamily
D0N37_RS01760	COG0629	single-stranded DNA binding
D0N37_RS01785	COG1792	Involved in formation and maintenance of cell shape
D0N37_RS01790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D0N37_RS01795	COG0424	maF-like protein
D0N37_RS01800	COG1530	ribonuclease E activity
D0N37_RS01810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0N37_RS01815	COG0312	modulator of DNA gyrase
D0N37_RS01830	COG2239	Acts as a magnesium transporter
D0N37_RS01840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0N37_RS01845	COG1660	Displays ATPase and GTPase activities
D0N37_RS01850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0N37_RS01855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0N37_RS01860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D0N37_RS01865	COG1137	ATPase activity
D0N37_RS01880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D0N37_RS01895	COG1127	ABC transporter
D0N37_RS01900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D0N37_RS01905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D0N37_RS01910	COG2854	intermembrane phospholipid transfer
D0N37_RS01920	COG5007	Belongs to the BolA IbaG family
D0N37_RS01925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0N37_RS01935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0N37_RS01945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D0N37_RS01950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D0N37_RS01955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D0N37_RS01960	COG0723	plastoquinol--plastocyanin reductase activity
D0N37_RS01965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0N37_RS01970	COG2857	Cytochrome c1
D0N37_RS01975	COG0625	glutathione transferase activity
D0N37_RS01980	COG2969	positive regulation of protein catabolic process
D0N37_RS01985	COG2823	Periplasmic or secreted lipoprotein
D0N37_RS02005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D0N37_RS02020	COG0745	RESPONSE REGULATOR receiver
D0N37_RS02060	COG1842	Phage shock protein A
D0N37_RS02065	COG1983	PspC domain protein
D0N37_RS02110	COG4771	TonB-dependent receptor
D0N37_RS02125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0N37_RS02130	COG2003	Belongs to the UPF0758 family
D0N37_RS02135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D0N37_RS02140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D0N37_RS02160	COG0745	RESPONSE REGULATOR receiver
D0N37_RS02160	COG2205	protein histidine kinase activity
D0N37_RS02160	COG3292	Two component regulator propeller
D0N37_RS02175	COG3852	Histidine kinase
D0N37_RS02180	COG3852	Histidine kinase
D0N37_RS02185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0N37_RS02190	COG0339	signal peptide processing
D0N37_RS02200	COG0742	ribosomal rna small subunit methyltransferase
D0N37_RS02210	COG1404	Belongs to the peptidase S8 family
D0N37_RS02215	COG2081	HI0933 family
D0N37_RS02220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS02240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0N37_RS02245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0N37_RS02250	COG1522	sequence-specific DNA binding
D0N37_RS02260	COG0194	GDP metabolic process
D0N37_RS02265	COG1758	RNA polymerase activity
D0N37_RS02270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0N37_RS02320	COG4181	ATPase activity
D0N37_RS02325	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D0N37_RS02350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0N37_RS02355	COG2897	thiosulfate sulfurtransferase activity
D0N37_RS02360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D0N37_RS02375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D0N37_RS02390	COG0137	argininosuccinate synthase activity
D0N37_RS02395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0N37_RS02395	COG0165	Argininosuccinate lyase
D0N37_RS02415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D0N37_RS02425	COG0301	tRNA thio-modification
D0N37_RS02425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0N37_RS02430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0N37_RS02440	COG1666	GTP binding
D0N37_RS02445	COG4206	TonB-dependent receptor
D0N37_RS02460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS02505	COG1047	Peptidyl-prolyl cis-trans
D0N37_RS02530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D0N37_RS02535	COG2824	Alkylphosphonate utilization operon protein PhnA
D0N37_RS02545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0N37_RS02550	COG0248	Ppx GppA phosphatase
D0N37_RS02555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D0N37_RS02570	COG0581	inorganic phosphate transmembrane transporter activity
D0N37_RS02575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0N37_RS02580	COG0704	Plays a role in the regulation of phosphate uptake
D0N37_RS02585	COG1392	Phosphate transport regulator
D0N37_RS02590	COG0306	phosphate transporter
D0N37_RS02595	COG0583	DNA-binding transcription factor activity
D0N37_RS02620	COG5002	protein histidine kinase activity
D0N37_RS02620	COG5001	Diguanylate cyclase
D0N37_RS02625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D0N37_RS02630	COG0343	queuine tRNA-ribosyltransferase activity
D0N37_RS02635	COG1862	Preprotein translocase
D0N37_RS02640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0N37_RS02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0N37_RS02655	COG2199	diguanylate cyclase activity
D0N37_RS02670	COG0840	transmembrane signaling receptor activity
D0N37_RS02675	COG1187	pseudouridine synthase activity
D0N37_RS02690	COG1280	lysine exporter protein (LysE YggA)
D0N37_RS02725	COG0151	Belongs to the GarS family
D0N37_RS02735	COG0138	bifunctional purine biosynthesis protein purh
D0N37_RS02740	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D0N37_RS02745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0N37_RS02750	COG2264	protein methyltransferase activity
D0N37_RS02770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D0N37_RS02775	COG0742	ribosomal rna small subunit methyltransferase
D0N37_RS02785	COG2884	Cell division ATP-binding protein ftsE
D0N37_RS02790	COG2177	Part of the ABC transporter FtsEX involved in
D0N37_RS02805	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
D0N37_RS02820	COG2067	long-chain fatty acid transport protein
D0N37_RS02840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D0N37_RS02845	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D0N37_RS02855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0N37_RS02860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D0N37_RS02885	COG3122	Protein conserved in bacteria
D0N37_RS02900	COG4948	Mandelate Racemase Muconate Lactonizing
D0N37_RS02915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D0N37_RS02920	COG1959	2 iron, 2 sulfur cluster binding
D0N37_RS02925	COG1104	cysteine desulfurase activity
D0N37_RS02930	COG0822	iron-sulfur transferase activity
D0N37_RS02935	COG0316	Belongs to the HesB IscA family
D0N37_RS02940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D0N37_RS02945	COG0443	Heat shock 70 kDa protein
D0N37_RS03010	COG0189	ligase activity
D0N37_RS03010	COG4067	protein conserved in archaea
D0N37_RS03015	COG0189	ligase activity
D0N37_RS03040	COG0514	ATP-dependent DNA helicase (RecQ)
D0N37_RS03045	COG2962	Rard protein
D0N37_RS03060	COG0583	DNA-binding transcription factor activity
D0N37_RS03095	COG0788	formyltetrahydrofolate deformylase activity
D0N37_RS03110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0N37_RS03125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0N37_RS03130	COG0126	phosphoglycerate kinase activity
D0N37_RS03150	COG0745	RESPONSE REGULATOR receiver
D0N37_RS03190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D0N37_RS03195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D0N37_RS03200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0N37_RS03210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0N37_RS03220	COG1489	DNA binding
D0N37_RS03225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0N37_RS03230	COG1125	glycine betaine transport
D0N37_RS03230	COG0517	IMP dehydrogenase activity
D0N37_RS03250	COG0793	Belongs to the peptidase S41A family
D0N37_RS03255	COG4942	peptidase
D0N37_RS03260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D0N37_RS03270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0N37_RS03275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D0N37_RS03280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D0N37_RS03295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0N37_RS03300	COG1196	nuclear chromosome segregation
D0N37_RS03310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D0N37_RS03320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0N37_RS03325	COG0745	RESPONSE REGULATOR receiver
D0N37_RS03400	COG1469	GTP cyclohydrolase I activity
D0N37_RS03405	COG5002	protein histidine kinase activity
D0N37_RS03405	COG0784	Response regulator, receiver
D0N37_RS03405	COG2198	Histidine kinase
D0N37_RS03410	COG0745	RESPONSE REGULATOR receiver
D0N37_RS03420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS03420	COG4191	Histidine kinase
D0N37_RS03425	COG2813	Specifically methylates the guanine in position
D0N37_RS03430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D0N37_RS03440	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
D0N37_RS03445	COG0142	geranyltranstransferase activity
D0N37_RS03450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0N37_RS03455	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D0N37_RS03460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D0N37_RS03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0N37_RS03500	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D0N37_RS03505	COG0047	phosphoribosylformylglycinamidine synthase activity
D0N37_RS03505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0N37_RS03520	COG3784	Protein of unknown function (DUF1318)
D0N37_RS03540	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D0N37_RS03545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0N37_RS03545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D0N37_RS03550	COG3642	lipopolysaccharide core region biosynthetic process
D0N37_RS03555	COG0859	PFAM glycosyl transferase family 9
D0N37_RS03560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D0N37_RS03570	COG1063	alcohol dehydrogenase
D0N37_RS03575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0N37_RS03580	COG0705	Rhomboid family
D0N37_RS03585	COG1580	Controls the rotational direction of flagella during chemotaxis
D0N37_RS03590	COG3161	chorismate lyase activity
D0N37_RS03595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D0N37_RS03600	COG0583	DNA-binding transcription factor activity
D0N37_RS03605	COG0784	Response regulator, receiver
D0N37_RS03605	COG3437	response regulator, receiver
D0N37_RS03620	COG3068	Protein conserved in bacteria
D0N37_RS03625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D0N37_RS03630	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D0N37_RS03645	COG1968	undecaprenyl-diphosphatase activity
D0N37_RS03655	COG0612	Peptidase, M16
D0N37_RS03660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0N37_RS03665	COG1045	serine acetyltransferase
D0N37_RS03670	COG1570	exodeoxyribonuclease VII activity
D0N37_RS03675	COG0517	IMP dehydrogenase activity
D0N37_RS03675	COG0516	GMP reductase activity
D0N37_RS03680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D0N37_RS03680	COG0519	Catalyzes the synthesis of GMP from XMP
D0N37_RS03700	COG0456	acetyltransferase
D0N37_RS03705	COG0784	Response regulator, receiver
D0N37_RS03705	COG2205	protein histidine kinase activity
D0N37_RS03720	COG3267	Type II secretory pathway component ExeA
D0N37_RS03720	COG3409	Peptidoglycan-binding domain 1 protein
D0N37_RS03735	COG1473	amidohydrolase
D0N37_RS03740	COG0739	heme binding
D0N37_RS03745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0N37_RS03750	COG3313	Fe-S protein
D0N37_RS03770	COG5001	Diguanylate cyclase
D0N37_RS03775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0N37_RS03780	COG0045	succinate-CoA ligase (ADP-forming) activity
D0N37_RS03780	COG1042	CoA-binding domain protein
D0N37_RS03780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0N37_RS03800	COG0494	nUDIX hydrolase
D0N37_RS03800	COG0406	alpha-ribazole phosphatase activity
D0N37_RS03805	COG0667	Aldo Keto reductase
D0N37_RS03810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0N37_RS03815	COG1966	Carbon starvation protein
D0N37_RS03820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0N37_RS03825	COG1295	ribonuclease BN
D0N37_RS03840	COG1115	amino acid carrier protein
D0N37_RS03850	COG3025	triphosphatase activity
D0N37_RS03860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D0N37_RS03865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0N37_RS03870	COG0840	transmembrane signaling receptor activity
D0N37_RS03875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D0N37_RS03880	COG2967	ApaG domain
D0N37_RS03885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D0N37_RS03890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D0N37_RS03895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0N37_RS03900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D0N37_RS03910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D0N37_RS03940	COG0205	6-phosphofructokinase activity
D0N37_RS03945	COG2315	Protein conserved in bacteria
D0N37_RS03960	COG1025	Belongs to the peptidase M16 family
D0N37_RS03965	COG2062	phosphohistidine phosphatase, SixA
D0N37_RS03970	COG4771	TonB-dependent receptor
D0N37_RS03980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0N37_RS03990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0N37_RS04015	COG0625	glutathione transferase activity
D0N37_RS04020	COG1404	Belongs to the peptidase S8 family
D0N37_RS04040	COG0739	heme binding
D0N37_RS04040	COG0741	lytic transglycosylase activity
D0N37_RS04040	COG1196	nuclear chromosome segregation
D0N37_RS04045	COG0179	Fumarylacetoacetate (FAA) hydrolase
D0N37_RS04055	COG3104	oligopeptide transport
D0N37_RS04060	COG0784	Response regulator, receiver
D0N37_RS04060	COG2205	protein histidine kinase activity
D0N37_RS04060	COG5002	protein histidine kinase activity
D0N37_RS04100	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
D0N37_RS04115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0N37_RS04125	COG2267	carboxylic ester hydrolase activity
D0N37_RS04130	COG2205	protein histidine kinase activity
D0N37_RS04135	COG0745	RESPONSE REGULATOR receiver
D0N37_RS04155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D0N37_RS04165	COG0784	Response regulator, receiver
D0N37_RS04170	COG1823	symporter activity
D0N37_RS04180	COG0564	pseudouridine synthase activity
D0N37_RS04185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0N37_RS04195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D0N37_RS04215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0N37_RS04220	COG0789	Transcriptional regulator
D0N37_RS04225	COG0701	Predicted permease
D0N37_RS04240	COG3148	PFAM DTW domain containing protein
D0N37_RS04260	COG3842	ATPase activity
D0N37_RS04275	COG1438	arginine binding
D0N37_RS04280	COG0039	L-malate dehydrogenase activity
D0N37_RS04285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0N37_RS04290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D0N37_RS04295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0N37_RS04310	COG3706	GGDEF domain
D0N37_RS04320	COG0004	ammonium transporteR
D0N37_RS04325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0N37_RS04330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0N37_RS04335	COG0540	Belongs to the ATCase OTCase family
D0N37_RS04340	COG1981	membrane
D0N37_RS04350	COG0316	Belongs to the HesB IscA family
D0N37_RS04360	COG2814	Major facilitator Superfamily
D0N37_RS04385	COG0271	Belongs to the BolA IbaG family
D0N37_RS04395	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0N37_RS04400	COG1805	sodium ion transport
D0N37_RS04405	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0N37_RS04410	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0N37_RS04415	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0N37_RS04420	COG2871	sodium ion transport
D0N37_RS04425	COG1477	protein flavinylation
D0N37_RS04440	COG1120	ATPase activity
D0N37_RS04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0N37_RS04450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D0N37_RS04455	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D0N37_RS04465	COG1492	cobalamin metabolic process
D0N37_RS04475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0N37_RS04500	COG3022	response to hydroperoxide
D0N37_RS04515	COG0189	ligase activity
D0N37_RS04520	COG0840	transmembrane signaling receptor activity
D0N37_RS04555	COG0697	spore germination
D0N37_RS04560	COG2974	May be involved in recombination
D0N37_RS04580	COG0083	homoserine kinase activity
D0N37_RS04585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D0N37_RS04590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0N37_RS04595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0N37_RS04600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0N37_RS04600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0N37_RS04615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D0N37_RS04620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0N37_RS04630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0N37_RS04635	COG3706	GGDEF domain
D0N37_RS04640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0N37_RS04645	COG0142	geranyltranstransferase activity
D0N37_RS04650	COG1722	exodeoxyribonuclease VII activity
D0N37_RS04655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0N37_RS04670	COG0814	amino acid
D0N37_RS04680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D0N37_RS04685	COG0321	lipoyl(octanoyl) transferase activity
D0N37_RS04690	COG2921	Belongs to the UPF0250 family
D0N37_RS04705	COG5433	transposase activity
D0N37_RS04715	COG1686	Belongs to the peptidase S11 family
D0N37_RS04720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0N37_RS04725	COG0772	Belongs to the SEDS family
D0N37_RS04730	COG0768	penicillin binding
D0N37_RS04735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D0N37_RS04740	COG0799	negative regulation of ribosome biogenesis
D0N37_RS04745	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0N37_RS04760	COG0495	leucyl-tRNA aminoacylation
D0N37_RS04780	COG0545	Peptidyl-prolyl cis-trans isomerase
D0N37_RS04795	COG1842	Phage shock protein A
D0N37_RS04805	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D0N37_RS04810	COG3766	membrane
D0N37_RS04830	COG0443	Heat shock 70 kDa protein
D0N37_RS04835	COG1803	Methylglyoxal synthase
D0N37_RS04840	COG1280	lysine exporter protein (LysE YggA)
D0N37_RS04855	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D0N37_RS04855	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D0N37_RS04855	COG0506	proline dehydrogenase activity
D0N37_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS04870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0N37_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS04890	COG3383	formate dehydrogenase (NAD+) activity
D0N37_RS04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0N37_RS04900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0N37_RS04905	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0N37_RS04915	COG0513	Belongs to the DEAD box helicase family
D0N37_RS04920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0N37_RS04930	COG0716	FMN binding
D0N37_RS04940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0N37_RS04955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D0N37_RS04995	COG1737	Transcriptional regulator
D0N37_RS05000	COG1757	Na H antiporter
D0N37_RS05025	COG3083	sulfuric ester hydrolase activity
D0N37_RS05030	COG5001	Diguanylate cyclase
D0N37_RS05045	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0N37_RS05060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0N37_RS05065	COG0527	aspartate kinase activity
D0N37_RS05070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D0N37_RS05080	COG3630	sodium ion export across plasma membrane
D0N37_RS05110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D0N37_RS05115	COG3036	rescue of stalled ribosome
D0N37_RS05130	COG2207	Transcriptional regulator
D0N37_RS05155	COG2315	Protein conserved in bacteria
D0N37_RS05175	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
D0N37_RS05190	COG0457	Tetratricopeptide repeat
D0N37_RS05220	COG4104	PAAR repeat-containing protein
D0N37_RS05285	COG0456	acetyltransferase
D0N37_RS05290	COG2010	Cytochrome c
D0N37_RS05355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0N37_RS05375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0N37_RS05390	COG0024	Methionine aminopeptidase
D0N37_RS05395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0N37_RS05445	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0N37_RS05460	COG1199	ATP-dependent helicase activity
D0N37_RS05465	COG0417	DNA replication proofreading
D0N37_RS05470	COG4771	TonB-dependent receptor
D0N37_RS05475	COG4206	TonB-dependent receptor
D0N37_RS05480	COG1643	Atp-dependent helicase
D0N37_RS05485	COG3228	Belongs to the MtfA family
D0N37_RS05500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0N37_RS05520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0N37_RS05535	COG1803	Methylglyoxal synthase
D0N37_RS05535	COG1597	lipid kinase activity
D0N37_RS05550	COG4251	negative regulation of phosphorylation
D0N37_RS05555	COG0784	Response regulator, receiver
D0N37_RS05560	COG0784	Response regulator, receiver
D0N37_RS05560	COG2205	protein histidine kinase activity
D0N37_RS05590	COG0668	transmembrane transport
D0N37_RS05620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D0N37_RS05625	COG0583	DNA-binding transcription factor activity
D0N37_RS05645	COG5001	Diguanylate cyclase
D0N37_RS05645	COG3300	MHYT domain
D0N37_RS05650	COG0418	dihydroorotase activity
D0N37_RS05660	COG1061	Type III restriction enzyme res subunit
D0N37_RS05675	COG2911	Protein conserved in bacteria
D0N37_RS05690	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0N37_RS05690	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0N37_RS05700	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
D0N37_RS05720	COG3152	Membrane
D0N37_RS05740	COG0564	pseudouridine synthase activity
D0N37_RS05755	COG0741	lytic transglycosylase activity
D0N37_RS05755	COG1388	LysM domain
D0N37_RS05760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0N37_RS05765	COG2226	methyltransferase
D0N37_RS05770	COG0328	RNA-DNA hybrid ribonuclease activity
D0N37_RS05845	COG2201	protein-glutamate methylesterase activity
D0N37_RS05850	COG0268	Binds directly to 16S ribosomal RNA
D0N37_RS05860	COG0196	riboflavin kinase activity
D0N37_RS05865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D0N37_RS05870	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D0N37_RS05875	COG1047	Peptidyl-prolyl cis-trans
D0N37_RS05880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D0N37_RS05885	COG2972	Histidine kinase
D0N37_RS05885	COG0745	RESPONSE REGULATOR receiver
D0N37_RS05935	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0N37_RS05940	COG0564	pseudouridine synthase activity
D0N37_RS05950	COG0542	response to heat
D0N37_RS05960	COG2918	glutathione biosynthetic process
D0N37_RS05970	COG4536	flavin adenine dinucleotide binding
D0N37_RS05975	COG4137	Cytochrome C assembly protein
D0N37_RS05980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0N37_RS05990	COG0228	four-way junction DNA binding
D0N37_RS05995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D0N37_RS06000	COG0336	Belongs to the RNA methyltransferase TrmD family
D0N37_RS06005	COG0335	large ribosomal subunit rRNA binding
D0N37_RS06010	COG1605	Chorismate mutase
D0N37_RS06010	COG0287	Prephenate dehydrogenase
D0N37_RS06035	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D0N37_RS06045	COG2161	toxin-antitoxin pair type II binding
D0N37_RS06050	COG4115	mRNA cleavage
D0N37_RS06105	COG0673	inositol 2-dehydrogenase activity
D0N37_RS06110	COG2207	Transcriptional regulator
D0N37_RS06110	COG0662	Cupin 2, conserved barrel domain protein
D0N37_RS06135	COG0077	Prephenate dehydratase
D0N37_RS06135	COG1605	Chorismate mutase
D0N37_RS06145	COG0023	Translation Initiation Factor
D0N37_RS06165	COG1448	Aminotransferase
D0N37_RS06170	COG3141	response to X-ray
D0N37_RS06185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0N37_RS06190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0N37_RS06195	COG3710	Transcriptional regulator
D0N37_RS06205	COG2186	Transcriptional regulator
D0N37_RS06210	COG0450	alkyl hydroperoxide reductase
D0N37_RS06220	COG2840	Smr protein MutS2
D0N37_RS06225	COG2890	protein-(glutamine-N5) methyltransferase activity
D0N37_RS06230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D0N37_RS06240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D0N37_RS06275	COG0544	peptidyl-prolyl cis-trans isomerase activity
D0N37_RS06280	COG0740	serine-type endopeptidase activity
D0N37_RS06285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D0N37_RS06290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D0N37_RS06300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0N37_RS06320	COG4172	Belongs to the ABC transporter superfamily
D0N37_RS06330	COG4171	peptide transport system, permease
D0N37_RS06335	COG4168	peptide transport system, permease
D0N37_RS06340	COG0747	negative chemotaxis
D0N37_RS06345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0N37_RS06350	COG1842	Phage shock protein A
D0N37_RS06360	COG1983	PspC domain protein
D0N37_RS06365	COG3106	COG3106 Predicted ATPase
D0N37_RS06370	COG3768	UPF0283 membrane protein
D0N37_RS06385	COG2154	pterin-4-alpha-carbinolamine dehydratase
D0N37_RS06400	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0N37_RS06405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0N37_RS06410	COG0215	cysteine-tRNA ligase activity
D0N37_RS06420	COG3264	Mechanosensitive ion channel
D0N37_RS06420	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D0N37_RS06425	COG0668	transmembrane transport
D0N37_RS06430	COG1346	cytolysis
D0N37_RS06445	COG3099	Belongs to the UPF0263 family
D0N37_RS06460	COG1047	Peptidyl-prolyl cis-trans
D0N37_RS06470	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D0N37_RS06480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D0N37_RS06505	COG0481	GTPase activity
D0N37_RS06515	COG0571	ribonuclease III activity
D0N37_RS06525	COG1381	Involved in DNA repair and RecF pathway recombination
D0N37_RS06530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D0N37_RS06535	COG4206	TonB-dependent receptor
D0N37_RS06540	COG2171	N-acyltransferase activity
D0N37_RS06545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D0N37_RS06550	COG0024	Methionine aminopeptidase
D0N37_RS06555	COG0052	Belongs to the universal ribosomal protein uS2 family
D0N37_RS06560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D0N37_RS06565	COG0528	UMP kinase activity
D0N37_RS06570	COG0233	cytoplasmic translational termination
D0N37_RS06575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0N37_RS06580	COG0575	Belongs to the CDS family
D0N37_RS06585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D0N37_RS06590	COG0750	zinc metalloprotease
D0N37_RS06605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0N37_RS06610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0N37_RS06615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0N37_RS06620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0N37_RS06625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0N37_RS06630	COG0587	DNA-directed DNA polymerase activity
D0N37_RS06635	COG0825	malonyl-CoA metabolic process
D0N37_RS06650	COG3706	GGDEF domain
D0N37_RS06725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0N37_RS06765	COG1396	sequence-specific DNA binding
D0N37_RS06785	COG0583	DNA-binding transcription factor activity
D0N37_RS06795	COG0145	ligase activity
D0N37_RS06800	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
D0N37_RS06805	COG4647	ligase activity
D0N37_RS06890	COG1757	Na H antiporter
D0N37_RS06925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0N37_RS06940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0N37_RS06945	COG0019	diaminopimelate decarboxylase activity
D0N37_RS06960	COG1131	(ABC) transporter
D0N37_RS06970	COG2755	lipolytic protein G-D-S-L family
D0N37_RS07000	COG0076	glutamate decarboxylase activity
D0N37_RS07005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0N37_RS07040	COG1846	Transcriptional regulator
D0N37_RS07075	COG2814	Major facilitator Superfamily
D0N37_RS07085	COG1451	nucleotide metabolic process
D0N37_RS07090	COG1801	Protein of unknown function DUF72
D0N37_RS07095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D0N37_RS07100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D0N37_RS07110	COG2255	four-way junction helicase activity
D0N37_RS07120	COG0811	peptide transport
D0N37_RS07125	COG0848	biopolymer transport protein
D0N37_RS07140	COG2885	chlorophyll binding
D0N37_RS07145	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D0N37_RS07190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D0N37_RS07205	COG4974	Belongs to the 'phage' integrase family
D0N37_RS07270	COG1902	pentaerythritol trinitrate reductase activity
D0N37_RS07285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D0N37_RS07290	COG1074	ATP-dependent DNA helicase activity
D0N37_RS07295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0N37_RS07305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D0N37_RS07315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0N37_RS07315	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D0N37_RS07320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0N37_RS07325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D0N37_RS07330	COG2867	negative regulation of translational initiation
D0N37_RS07335	COG2914	Belongs to the UPF0125 (RnfH) family
D0N37_RS07340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0N37_RS07345	COG2827	Endonuclease containing a URI domain
D0N37_RS07350	COG2234	aminopeptidase activity
D0N37_RS07360	COG0840	transmembrane signaling receptor activity
D0N37_RS07365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D0N37_RS07375	COG0745	RESPONSE REGULATOR receiver
D0N37_RS07410	COG4326	sporulation control protein
D0N37_RS07420	COG0733	neurotransmitter:sodium symporter activity
D0N37_RS07430	COG0745	RESPONSE REGULATOR receiver
D0N37_RS07445	COG1534	Rna-binding protein
D0N37_RS07450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D0N37_RS07455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0N37_RS07460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D0N37_RS07465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0N37_RS07470	COG0149	triose-phosphate isomerase activity
D0N37_RS07475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0N37_RS07485	COG4771	TonB-dependent receptor
D0N37_RS07510	COG2205	protein histidine kinase activity
D0N37_RS07510	COG3292	Two component regulator propeller
D0N37_RS07510	COG0745	RESPONSE REGULATOR receiver
D0N37_RS07540	COG0121	glutamine amidotransferase
D0N37_RS07550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0N37_RS07555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0N37_RS07580	COG2854	intermembrane phospholipid transfer
D0N37_RS07585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0N37_RS07590	COG0386	Belongs to the glutathione peroxidase family
D0N37_RS07595	COG2084	Dehydrogenase
D0N37_RS07600	COG1876	peptidase activity
D0N37_RS07605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0N37_RS07610	COG1393	Belongs to the ArsC family
D0N37_RS07625	COG0857	belongs to the CobB CobQ family
D0N37_RS07625	COG0280	phosphate acetyltransferase
D0N37_RS07630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0N37_RS07635	COG3092	negative regulation of chromosome organization
D0N37_RS07640	COG2226	methyltransferase
D0N37_RS07650	COG0708	Exodeoxyribonuclease III
D0N37_RS07670	COG0513	Belongs to the DEAD box helicase family
D0N37_RS07675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0N37_RS07680	COG2194	sulfuric ester hydrolase activity
D0N37_RS07695	COG2205	protein histidine kinase activity
D0N37_RS07705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D0N37_RS07725	COG1301	dicarboxylic acid transport
D0N37_RS07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0N37_RS07745	COG2862	Uncharacterized protein family, UPF0114
D0N37_RS07760	COG1131	(ABC) transporter
D0N37_RS07765	COG2188	Transcriptional regulator
D0N37_RS07770	COG0596	Alpha beta hydrolase
D0N37_RS07775	COG4555	ABC transporter
D0N37_RS07785	COG0037	tRNA processing
D0N37_RS07805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0N37_RS07820	COG2217	Heavy metal translocating P-type atpase
D0N37_RS07830	COG2010	Cytochrome c
D0N37_RS07845	COG3278	Belongs to the heme-copper respiratory oxidase family
D0N37_RS07885	COG0583	DNA-binding transcription factor activity
D0N37_RS07890	COG0659	secondary active sulfate transmembrane transporter activity
D0N37_RS07895	COG1530	ribonuclease E activity
D0N37_RS07900	COG0564	pseudouridine synthase activity
D0N37_RS07905	COG0546	phosphoglycolate phosphatase activity
D0N37_RS07910	COG0424	maF-like protein
D0N37_RS07915	COG1399	metal-binding, possibly nucleic acid-binding protein
D0N37_RS07920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D0N37_RS07925	COG0416	fatty acid biosynthetic process
D0N37_RS07940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0N37_RS07945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0N37_RS07955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0N37_RS07960	COG2095	MarC family integral membrane protein
D0N37_RS07990	COG3082	Protein of unknown function (DUF1414)
D0N37_RS07995	COG3081	Nucleoid-associated protein
D0N37_RS08040	COG0628	permease
D0N37_RS08065	COG2350	Protein conserved in bacteria
D0N37_RS08070	COG0733	neurotransmitter:sodium symporter activity
D0N37_RS08085	COG0776	regulation of translation
D0N37_RS08100	COG0134	indole-3-glycerol-phosphate synthase activity
D0N37_RS08100	COG0135	phosphoribosylanthranilate isomerase activity
D0N37_RS08105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D0N37_RS08110	COG0512	Glutamine amidotransferase of anthranilate synthase
D0N37_RS08115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0N37_RS08120	COG0009	L-threonylcarbamoyladenylate synthase
D0N37_RS08130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D0N37_RS08135	COG1187	pseudouridine synthase activity
D0N37_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS08150	COG2267	carboxylic ester hydrolase activity
D0N37_RS08155	COG0616	signal peptide processing
D0N37_RS08175	COG0583	DNA-binding transcription factor activity
D0N37_RS08200	COG4942	peptidase
D0N37_RS08205	COG2311	Membrane
D0N37_RS08215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0N37_RS08230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0N37_RS08245	COG0662	Cupin 2, conserved barrel domain protein
D0N37_RS08270	COG1671	Belongs to the UPF0178 family
D0N37_RS08315	COG1252	NADH dehydrogenase
D0N37_RS08340	COG1280	lysine exporter protein (LysE YggA)
D0N37_RS08355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0N37_RS08355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0N37_RS08365	COG0717	Belongs to the dCTP deaminase family
D0N37_RS08370	COG4251	negative regulation of phosphorylation
D0N37_RS08370	COG3706	GGDEF domain
D0N37_RS08370	COG2203	Gaf domain
D0N37_RS08370	COG5001	Diguanylate cyclase
D0N37_RS08390	COG0436	Aminotransferase
D0N37_RS08400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0N37_RS08415	COG3604	Transcriptional regulator
D0N37_RS08425	COG3038	cytochrome b561
D0N37_RS08430	COG2353	YceI-like domain
D0N37_RS08460	COG0784	Response regulator, receiver
D0N37_RS08460	COG2205	protein histidine kinase activity
D0N37_RS08515	COG0307	riboflavin synthase, alpha
D0N37_RS08525	COG3001	Fructosamine kinase
D0N37_RS08540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0N37_RS08565	COG2920	part of a sulfur-relay system
D0N37_RS08585	COG0670	Belongs to the BI1 family
D0N37_RS08605	COG1956	GAF domain-containing protein
D0N37_RS08615	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
D0N37_RS08625	COG1757	Na H antiporter
D0N37_RS08630	COG0308	aminopeptidase N
D0N37_RS08660	COG2902	Dehydrogenase
D0N37_RS08665	COG0167	dihydroorotate dehydrogenase activity
D0N37_RS08680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0N37_RS08680	COG0116	Belongs to the methyltransferase superfamily
D0N37_RS08690	COG0488	(ABC) transporter
D0N37_RS08705	COG2333	competence protein COMEC
D0N37_RS08705	COG0658	competence protein
D0N37_RS08710	COG1132	(ABC) transporter
D0N37_RS08715	COG1663	tetraacyldisaccharide 4'-kinase activity
D0N37_RS08720	COG2835	tetraacyldisaccharide 4'-kinase activity
D0N37_RS08725	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D0N37_RS08730	COG0564	pseudouridine synthase activity
D0N37_RS08735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D0N37_RS08740	COG2166	iron-sulfur cluster assembly
D0N37_RS08745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0N37_RS08760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D0N37_RS08775	COG0567	Dehydrogenase, E1 component
D0N37_RS08780	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0N37_RS08785	COG0045	succinate-CoA ligase (ADP-forming) activity
D0N37_RS08800	COG2329	Antibiotic biosynthesis monooxygenase
D0N37_RS08810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0N37_RS08815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0N37_RS08820	COG3938	Belongs to the proline racemase family
D0N37_RS08865	COG1136	(ABC) transporter
D0N37_RS08895	COG0753	catalase activity
D0N37_RS08900	COG0318	PFAM AMP-dependent synthetase and ligase
D0N37_RS08915	COG1309	transcriptional regulator
D0N37_RS08920	COG1132	(ABC) transporter
D0N37_RS08945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D0N37_RS08950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D0N37_RS08955	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D0N37_RS08960	COG0300	oxidoreductase activity
D0N37_RS08970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0N37_RS08975	COG1522	sequence-specific DNA binding
D0N37_RS08980	COG0659	secondary active sulfate transmembrane transporter activity
D0N37_RS08995	COG0469	pyruvate kinase activity
D0N37_RS09000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0N37_RS09005	COG0252	asparaginase activity
D0N37_RS09010	COG0616	signal peptide processing
D0N37_RS09015	COG1902	pentaerythritol trinitrate reductase activity
D0N37_RS09015	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0N37_RS09035	COG0778	Nitroreductase
D0N37_RS09040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D0N37_RS09060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0N37_RS09070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0N37_RS09080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0N37_RS09090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D0N37_RS09095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D0N37_RS09100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D0N37_RS09105	COG0539	negative regulation of cytoplasmic translation
D0N37_RS09110	COG0776	regulation of translation
D0N37_RS09120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D0N37_RS09125	COG0284	orotidine-5'-phosphate decarboxylase activity
D0N37_RS09290	COG0737	Belongs to the 5'-nucleotidase family
D0N37_RS09300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0N37_RS09305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS09310	COG4667	esterase of the alpha-beta hydrolase superfamily
D0N37_RS09325	COG0513	Belongs to the DEAD box helicase family
D0N37_RS09330	COG1054	Belongs to the UPF0176 family
D0N37_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
D0N37_RS09340	COG0009	L-threonylcarbamoyladenylate synthase
D0N37_RS09370	COG0545	Peptidyl-prolyl cis-trans isomerase
D0N37_RS09395	COG0017	Asparaginyl-tRNA synthetase
D0N37_RS09410	COG2204	response regulator
D0N37_RS09430	COG2056	Na+-H+ antiporter family
D0N37_RS09445	COG0714	Associated with various cellular activities
D0N37_RS09450	COG3279	Response regulator of the LytR AlgR family
D0N37_RS09555	COG2369	cell adhesion
D0N37_RS09755	COG5005	Phage virion morphogenesis
D0N37_RS09845	COG1204	response to ionizing radiation
D0N37_RS09910	COG3788	relative of glutathione S-transferase, MAPEG superfamily
D0N37_RS09920	COG0281	malic enzyme
D0N37_RS09925	COG0405	Gamma-glutamyltransferase
D0N37_RS09940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0N37_RS09945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0N37_RS09955	COG1309	transcriptional regulator
D0N37_RS09960	COG0501	Belongs to the peptidase M48B family
D0N37_RS09980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D0N37_RS09985	COG2226	methyltransferase
D0N37_RS09990	COG0156	8-amino-7-oxononanoate synthase activity
D0N37_RS09995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D0N37_RS10005	COG1509	lysine 2,3-aminomutase activity
D0N37_RS10055	COG2204	response regulator
D0N37_RS10060	COG1607	acyl-coa hydrolase
D0N37_RS10075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0N37_RS10080	COG3130	regulation of translation
D0N37_RS10085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0N37_RS10090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0N37_RS10095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0N37_RS10100	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D0N37_RS10105	COG0531	amino acid
D0N37_RS10105	COG1674	ftsk spoiiie
D0N37_RS10115	COG0686	Belongs to the AlaDH PNT family
D0N37_RS10125	COG0840	transmembrane signaling receptor activity
D0N37_RS10135	COG2957	Belongs to the agmatine deiminase family
D0N37_RS10145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0N37_RS10165	COG0022	dehydrogenase e1 component
D0N37_RS10180	COG0033	Phosphoglucomutase
D0N37_RS10185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
D0N37_RS10190	COG0596	Alpha beta hydrolase
D0N37_RS10205	COG0716	FMN binding
D0N37_RS10230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0N37_RS10275	COG1720	tRNA m6t6A37 methyltransferase activity
D0N37_RS10280	COG0442	prolyl-tRNA aminoacylation
D0N37_RS10300	COG1668	transmembrane transport
D0N37_RS10305	COG4555	ABC transporter
D0N37_RS10360	COG5433	transposase activity
D0N37_RS10390	COG3547	Transposase (IS116 IS110 IS902 family)
D0N37_RS10415	COG2423	ornithine cyclodeaminase activity
D0N37_RS10420	COG0006	proline dipeptidase activity
D0N37_RS10435	COG4191	Histidine kinase
D0N37_RS10435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS10445	COG0084	hydrolase, TatD family'
D0N37_RS10460	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D0N37_RS10470	COG2205	protein histidine kinase activity
D0N37_RS10470	COG0784	Response regulator, receiver
D0N37_RS10490	COG1764	response to oxidative stress
D0N37_RS10500	COG0583	DNA-binding transcription factor activity
D0N37_RS10515	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0N37_RS10525	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0N37_RS10530	COG1522	sequence-specific DNA binding
D0N37_RS10545	COG1253	flavin adenine dinucleotide binding
D0N37_RS10555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0N37_RS10555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0N37_RS10575	COG1984	allophanate hydrolase subunit 2
D0N37_RS10590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D0N37_RS10595	COG0367	asparagine synthase
D0N37_RS10600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0N37_RS10605	COG0492	ferredoxin-NADP+ reductase activity
D0N37_RS10610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D0N37_RS10615	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
D0N37_RS10620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D0N37_RS10625	COG0542	response to heat
D0N37_RS10630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D0N37_RS10635	COG1278	Cold shock
D0N37_RS10645	COG1187	pseudouridine synthase activity
D0N37_RS10650	COG0482	sulfurtransferase activity
D0N37_RS10655	COG2915	High frequency lysogenization protein hflD homolog
D0N37_RS10660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0N37_RS10665	COG2850	peptidyl-arginine hydroxylation
D0N37_RS10680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS10680	COG4191	Histidine kinase
D0N37_RS10700	COG0346	lactoylglutathione lyase activity
D0N37_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS10715	COG1024	Enoyl-CoA hydratase
D0N37_RS10720	COG1024	Enoyl-CoA hydratase
D0N37_RS10735	COG0183	Belongs to the thiolase family
D0N37_RS10740	COG0789	Transcriptional regulator
D0N37_RS10745	COG1960	acyl-CoA dehydrogenase activity
D0N37_RS10750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0N37_RS10760	COG4770	biotin carboxylase activity
D0N37_RS10770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0N37_RS10780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0N37_RS10785	COG2176	DNA-directed DNA polymerase activity
D0N37_RS10790	COG0517	IMP dehydrogenase activity
D0N37_RS10805	COG3724	N-succinylarginine dihydrolase activity
D0N37_RS10835	COG1131	(ABC) transporter
D0N37_RS10860	COG0642	Histidine kinase
D0N37_RS10895	COG0530	calcium, potassium:sodium antiporter activity
D0N37_RS10900	COG1166	arginine decarboxylase activity
D0N37_RS10905	COG0010	Belongs to the arginase family
D0N37_RS10910	COG1846	Transcriptional regulator
D0N37_RS10935	COG4191	Histidine kinase
D0N37_RS10935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS10965	COG3139	Protein of unknown function (DUF1315)
D0N37_RS10975	COG1115	amino acid carrier protein
D0N37_RS10980	COG2866	Carboxypeptidase
D0N37_RS10995	COG0733	neurotransmitter:sodium symporter activity
D0N37_RS11005	COG0527	aspartate kinase activity
D0N37_RS11010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0N37_RS11050	COG0626	cystathionine gamma-synthase activity
D0N37_RS11060	COG0363	glucosamine-6-phosphate deaminase activity
D0N37_RS11075	COG2971	BadF BadG BcrA BcrD
D0N37_RS11085	COG0745	RESPONSE REGULATOR receiver
D0N37_RS11100	COG2226	methyltransferase
D0N37_RS11105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0N37_RS11115	COG0563	adenylate kinase activity
D0N37_RS11135	COG1609	Transcriptional regulator
D0N37_RS11140	COG0837	glucose binding
D0N37_RS11175	COG0366	Alpha amylase catalytic
D0N37_RS11185	COG0776	regulation of translation
D0N37_RS11190	COG0072	phenylalanine-tRNA ligase activity
D0N37_RS11215	COG0346	lactoylglutathione lyase activity
D0N37_RS11225	COG3291	Pkd domain containing protein
D0N37_RS11240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0N37_RS11245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0N37_RS11250	COG0505	Belongs to the CarA family
D0N37_RS11255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D0N37_RS11275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0N37_RS11340	COG0322	excinuclease ABC activity
D0N37_RS11345	COG2197	response regulator
D0N37_RS11365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0N37_RS11375	COG0602	queuosine metabolic process
D0N37_RS11380	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D0N37_RS11420	COG2252	PERMEase
D0N37_RS11435	COG3012	SEC-C Motif Domain Protein
D0N37_RS11490	COG1418	mRNA catabolic process
D0N37_RS11495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0N37_RS11505	COG0745	RESPONSE REGULATOR receiver
D0N37_RS11510	COG1643	Atp-dependent helicase
D0N37_RS11515	COG4109	DRTGG domain
D0N37_RS11550	COG0363	glucosamine-6-phosphate deaminase activity
D0N37_RS11555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0N37_RS11560	COG0166	Belongs to the GPI family
D0N37_RS11565	COG1609	Transcriptional regulator
D0N37_RS11585	COG4783	chaperone-mediated protein folding
D0N37_RS11590	COG1393	Belongs to the ArsC family
D0N37_RS11625	COG2205	protein histidine kinase activity
D0N37_RS11625	COG0784	Response regulator, receiver
D0N37_RS11640	COG0210	DNA helicase
D0N37_RS11665	COG0109	protoheme IX farnesyltransferase activity
D0N37_RS11675	COG1845	cytochrome c oxidase, subunit III
D0N37_RS11685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0N37_RS11735	COG0488	(ABC) transporter
D0N37_RS11745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0N37_RS11750	COG0814	amino acid
D0N37_RS11755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0N37_RS11775	COG2885	chlorophyll binding
D0N37_RS11810	COG0784	Response regulator, receiver
D0N37_RS11810	COG2205	protein histidine kinase activity
D0N37_RS11825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0N37_RS11830	COG1420	regulation of RNA biosynthetic process
D0N37_RS11845	COG0497	DNA recombination
D0N37_RS11855	COG0493	'glutamate synthase
D0N37_RS11860	COG0069	glutamate synthase activity
D0N37_RS11860	COG0067	glutamate synthase
D0N37_RS11860	COG0070	glutamate synthase
D0N37_RS11865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D0N37_RS11870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0N37_RS11875	COG2766	serine protein kinase
D0N37_RS11880	COG2718	Belongs to the UPF0229 family
D0N37_RS11885	COG2719	SpoVR family
D0N37_RS11890	COG3706	GGDEF domain
D0N37_RS11895	COG2201	protein-glutamate methylesterase activity
D0N37_RS11900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D0N37_RS11905	COG0326	Molecular chaperone. Has ATPase activity
D0N37_RS11910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0N37_RS11915	COG3590	peptidase
D0N37_RS11940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0N37_RS11945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0N37_RS11950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0N37_RS11960	COG3220	belongs to the UPF0276 family
D0N37_RS11970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0N37_RS11995	COG0848	biopolymer transport protein
D0N37_RS12000	COG0811	peptide transport
D0N37_RS12005	COG0811	peptide transport
D0N37_RS12040	COG1760	l-serine dehydratase
D0N37_RS12120	COG3314	Sporulation integral membrane protein YlbJ
D0N37_RS12130	COG2716	regulation of RNA biosynthetic process
D0N37_RS12135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0N37_RS12140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0N37_RS12145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0N37_RS12165	COG3088	subunit of a heme lyase
D0N37_RS12165	COG4235	cytochrome complex assembly
D0N37_RS12180	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
D0N37_RS12185	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0N37_RS12190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0N37_RS12195	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0N37_RS12200	COG4133	protoheme IX ABC transporter activity
D0N37_RS12225	COG0835	chemotaxis
D0N37_RS12235	COG1192	Involved in chromosome partitioning
D0N37_RS12240	COG2201	protein-glutamate methylesterase activity
D0N37_RS12245	COG0643	Histidine kinase
D0N37_RS12245	COG2198	Histidine kinase
D0N37_RS12245	COG0784	Response regulator, receiver
D0N37_RS12250	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D0N37_RS12275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0N37_RS12280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0N37_RS12290	COG1987	bacterial-type flagellum assembly
D0N37_RS12300	COG3190	flagellar
D0N37_RS12320	COG3144	bacterial-type flagellum assembly
D0N37_RS12340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0N37_RS12345	COG1766	The M ring may be actively involved in energy transduction
D0N37_RS12350	COG1677	Flagellar hook-basal body complex protein FliE
D0N37_RS12365	COG0519	Catalyzes the synthesis of GMP from XMP
D0N37_RS12375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0N37_RS12380	COG1086	Polysaccharide biosynthesis protein
D0N37_RS12385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0N37_RS12410	COG2089	acid synthase
D0N37_RS12415	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D0N37_RS12425	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D0N37_RS12440	COG3959	Transketolase, thiamine diphosphate binding domain
D0N37_RS12445	COG3958	Transketolase
D0N37_RS12460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D0N37_RS12470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D0N37_RS12515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D0N37_RS12535	COG4310	Domain of unknown function (DUF2172)
D0N37_RS12550	COG1516	flagellar protein fliS
D0N37_RS12585	COG1256	bacterial-type flagellum assembly
D0N37_RS12590	COG3951	Flagellar rod assembly protein muramidase FlgJ
D0N37_RS12590	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0N37_RS12595	COG1706	bacterial-type flagellum-dependent cell motility
D0N37_RS12600	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D0N37_RS12605	COG4786	Flagellar basal body rod
D0N37_RS12610	COG4786	Flagellar basal body rod
D0N37_RS12630	COG1815	bacterial-type flagellum-dependent cell motility
D0N37_RS12635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D0N37_RS12720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0N37_RS12725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D0N37_RS12730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D0N37_RS12735	COG0730	response to heat
D0N37_RS12740	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
D0N37_RS12745	COG1051	belongs to the nudix hydrolase family
D0N37_RS12750	COG3066	DNA modification
D0N37_RS12760	COG0148	phosphopyruvate hydratase activity
D0N37_RS12770	COG0504	CTP synthase activity
D0N37_RS12775	COG3956	TIGRFAM MazG family protein
D0N37_RS12780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0N37_RS12785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0N37_RS12790	COG3437	response regulator, receiver
D0N37_RS12790	COG3850	Histidine kinase
D0N37_RS12790	COG4999	Histidine kinase
D0N37_RS12790	COG2205	protein histidine kinase activity
D0N37_RS12800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D0N37_RS12805	COG1286	toxin biosynthetic process
D0N37_RS12815	COG0285	dihydrofolate synthase activity
D0N37_RS12820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D0N37_RS12825	COG0101	tRNA pseudouridine synthase activity
D0N37_RS12840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0N37_RS12850	COG1960	acyl-CoA dehydrogenase activity
D0N37_RS12860	COG3710	Transcriptional regulator
D0N37_RS12880	COG2986	histidine ammonia-lyase
D0N37_RS12895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0N37_RS12900	COG1131	(ABC) transporter
D0N37_RS12910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0N37_RS12915	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS12925	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D0N37_RS12930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0N37_RS12945	COG0644	oxidoreductase
D0N37_RS12965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D0N37_RS12975	COG1454	alcohol dehydrogenase
D0N37_RS13000	COG2832	Protein of unknown function (DUF454)
D0N37_RS13005	COG0840	transmembrane signaling receptor activity
D0N37_RS13020	COG2207	Transcriptional regulator
D0N37_RS13035	COG4191	Histidine kinase
D0N37_RS13050	COG1136	(ABC) transporter
D0N37_RS13050	COG0577	efflux transmembrane transporter activity
D0N37_RS13075	COG1643	Atp-dependent helicase
D0N37_RS13095	COG1410	methionine synthase
D0N37_RS13095	COG0646	methionine synthase
D0N37_RS13100	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D0N37_RS13105	COG0697	spore germination
D0N37_RS13175	COG0405	Gamma-glutamyltransferase
D0N37_RS13195	COG0583	DNA-binding transcription factor activity
D0N37_RS13205	COG1902	pentaerythritol trinitrate reductase activity
D0N37_RS13210	COG1881	PFAM PEBP family protein
D0N37_RS13225	COG0644	oxidoreductase
D0N37_RS13505	COG0488	(ABC) transporter
D0N37_RS13515	COG3766	membrane
D0N37_RS13525	COG0754	glutathionylspermidine amidase activity
D0N37_RS13555	COG0745	RESPONSE REGULATOR receiver
D0N37_RS13560	COG5002	protein histidine kinase activity
D0N37_RS13595	COG0840	transmembrane signaling receptor activity
D0N37_RS13600	COG1320	monovalent cation:proton antiporter activity
D0N37_RS13605	COG2212	antiporter activity
D0N37_RS13610	COG1863	multisubunit Na H antiporter MnhE subunit
D0N37_RS13615	COG0651	ATP synthesis coupled electron transport
D0N37_RS13620	COG1006	Multisubunit Na H antiporter MnhC subunit
D0N37_RS13625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0N37_RS13625	COG2111	Na H antiporter
D0N37_RS13640	COG1185	polyribonucleotide nucleotidyltransferase activity
D0N37_RS13645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D0N37_RS13650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D0N37_RS13655	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D0N37_RS13660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D0N37_RS13665	COG0195	Participates in both transcription termination and antitermination
D0N37_RS13670	COG0779	Required for maturation of 30S ribosomal subunits
D0N37_RS13695	COG0415	Belongs to the DNA photolyase family
D0N37_RS13700	COG3046	protein related to deoxyribodipyrimidine photolyase
D0N37_RS13740	COG0071	Belongs to the small heat shock protein (HSP20) family
D0N37_RS13750	COG3047	cAMP biosynthetic process
D0N37_RS13845	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0N37_RS13885	COG3119	arylsulfatase activity
D0N37_RS13890	COG2354	Protein conserved in bacteria
D0N37_RS13945	COG2199	diguanylate cyclase activity
D0N37_RS13945	COG2200	EAL domain
D0N37_RS13945	COG2203	Gaf domain
D0N37_RS13965	COG0513	Belongs to the DEAD box helicase family
D0N37_RS13975	COG0513	Belongs to the DEAD box helicase family
D0N37_RS13980	COG0702	epimerase
D0N37_RS13995	COG4585	Histidine kinase
D0N37_RS14000	COG2197	response regulator
D0N37_RS14010	COG0604	alcohol dehydrogenase
D0N37_RS14015	COG1309	transcriptional regulator
D0N37_RS14055	COG2205	protein histidine kinase activity
D0N37_RS14060	COG0745	RESPONSE REGULATOR receiver
D0N37_RS14110	COG4585	Histidine kinase
D0N37_RS14115	COG2197	response regulator
D0N37_RS14130	COG4771	TonB-dependent receptor
D0N37_RS14135	COG0657	acetylesterase activity
D0N37_RS14150	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0N37_RS14155	COG1505	serine-type exopeptidase activity
D0N37_RS14165	COG2130	NADP-dependent
D0N37_RS14175	COG0583	DNA-binding transcription factor activity
D0N37_RS14220	COG5433	transposase activity
D0N37_RS14355	COG1196	nuclear chromosome segregation
D0N37_RS14375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0N37_RS14375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0N37_RS14380	COG0509	glycine decarboxylation via glycine cleavage system
D0N37_RS14385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D0N37_RS14410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0N37_RS14415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0N37_RS14420	COG0006	proline dipeptidase activity
D0N37_RS14435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0N37_RS14445	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D0N37_RS14450	COG3023	N-Acetylmuramoyl-L-alanine amidase
D0N37_RS14455	COG0157	Belongs to the NadC ModD family
D0N37_RS14460	COG4969	Belongs to the N-Me-Phe pilin family
D0N37_RS14470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D0N37_RS14475	COG0237	dephospho-CoA kinase activity
D0N37_RS14485	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D0N37_RS14500	COG0330	HflC and HflK could
D0N37_RS14505	COG3457	Alanine racemase
D0N37_RS14515	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
D0N37_RS14520	COG2363	Small membrane protein
D0N37_RS14530	COG0583	DNA-binding transcription factor activity
D0N37_RS14535	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D0N37_RS14555	COG0784	Response regulator, receiver
D0N37_RS14555	COG3437	response regulator, receiver
D0N37_RS14560	COG2890	protein-(glutamine-N5) methyltransferase activity
D0N37_RS14565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D0N37_RS14570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D0N37_RS14575	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D0N37_RS14590	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D0N37_RS14595	COG0193	aminoacyl-tRNA hydrolase activity
D0N37_RS14600	COG0012	GTP binding
D0N37_RS14675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0N37_RS14680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0N37_RS14685	COG1702	phosphate starvation-inducible protein PhoH
D0N37_RS14690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D0N37_RS14695	COG4535	Mg2 and Co2 transporter CorC
D0N37_RS14700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D0N37_RS14715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0N37_RS14735	COG0556	nucleotide-excision repair
D0N37_RS14740	COG0534	Mate efflux family protein
D0N37_RS14765	COG2199	diguanylate cyclase activity
D0N37_RS14765	COG2200	EAL domain
D0N37_RS14765	COG2203	Gaf domain
D0N37_RS14770	COG4657	Part of a membrane complex involved in electron transport
D0N37_RS14775	COG2878	Part of a membrane complex involved in electron transport
D0N37_RS14785	COG4658	electron transport chain
D0N37_RS14795	COG4660	Part of a membrane complex involved in electron transport
D0N37_RS14800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0N37_RS14820	COG1982	Orn Lys Arg decarboxylase major
D0N37_RS14830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0N37_RS14840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0N37_RS14845	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0N37_RS14850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D0N37_RS14855	COG2186	Transcriptional regulator
D0N37_RS14925	COG0560	Phosphoserine phosphatase
D0N37_RS14945	COG0084	hydrolase, TatD family'
D0N37_RS14950	COG0259	pyridoxamine-phosphate oxidase activity
D0N37_RS14955	COG0018	arginyl-trna synthetase
D0N37_RS14990	COG1846	Transcriptional regulator
D0N37_RS14995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0N37_RS15010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0N37_RS15025	COG1228	amidohydrolase
D0N37_RS15045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0N37_RS15055	COG0187	DNA topoisomerase II activity
D0N37_RS15060	COG3150	esterase
D0N37_RS15070	COG3151	Protein conserved in bacteria
D0N37_RS15075	COG0494	nUDIX hydrolase
D0N37_RS15080	COG1538	Outer membrane efflux protein
D0N37_RS15085	COG1560	Kdo2-lipid A biosynthetic process
D0N37_RS15100	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D0N37_RS15115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0N37_RS15125	COG1678	Uncharacterized ACR, COG1678
D0N37_RS15130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D0N37_RS15155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0N37_RS15160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0N37_RS15165	COG0762	integral membrane protein
D0N37_RS15175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0N37_RS15180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0N37_RS15190	COG4191	Histidine kinase
D0N37_RS15190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS15195	COG3300	MHYT domain
D0N37_RS15195	COG5001	Diguanylate cyclase
D0N37_RS15215	COG0795	lipopolysaccharide-transporting ATPase activity
D0N37_RS15220	COG0795	lipopolysaccharide-transporting ATPase activity
D0N37_RS15225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0N37_RS15230	COG2927	DNA polymerase III (CHI subunit)
D0N37_RS15235	COG0525	valine-tRNA ligase activity
D0N37_RS15250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D0N37_RS15255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D0N37_RS15260	COG0585	pseudouridine synthase activity
D0N37_RS15265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D0N37_RS15270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0N37_RS15275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D0N37_RS15310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0N37_RS15320	COG0330	HflC and HflK could
D0N37_RS15330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0N37_RS15335	COG1923	regulation of RNA biosynthetic process
D0N37_RS15340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D0N37_RS15345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D0N37_RS15350	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0N37_RS15355	COG0802	atpase or kinase
D0N37_RS15360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0N37_RS15360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D0N37_RS15365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0N37_RS15375	COG2205	protein histidine kinase activity
D0N37_RS15380	COG1247	-acetyltransferase
D0N37_RS15410	COG1160	GTP binding
D0N37_RS15415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0N37_RS15420	COG2976	Protein conserved in bacteria
D0N37_RS15425	COG0124	histidyl-tRNA synthetase
D0N37_RS15430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D0N37_RS15435	COG1426	Protein conserved in bacteria
D0N37_RS15440	COG3063	Type IV pilus biogenesis stability protein PilW
D0N37_RS15445	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D0N37_RS15450	COG0105	UTP biosynthetic process
D0N37_RS15460	COG0826	peptidase U32
D0N37_RS15465	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D0N37_RS15470	COG4251	negative regulation of phosphorylation
D0N37_RS15475	COG0784	Response regulator, receiver
D0N37_RS15490	COG2197	response regulator
D0N37_RS15495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D0N37_RS15500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D0N37_RS15505	COG1561	YicC-like family, N-terminal region
D0N37_RS15605	COG1061	Type III restriction enzyme res subunit
D0N37_RS15640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0N37_RS15645	COG0583	DNA-binding transcription factor activity
D0N37_RS15655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D0N37_RS15665	COG1227	inorganic diphosphatase activity
D0N37_RS15690	COG0076	glutamate decarboxylase activity
D0N37_RS15700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D0N37_RS15705	COG0842	Transport permease protein
D0N37_RS15710	COG1131	(ABC) transporter
D0N37_RS15715	COG0163	prenyltransferase activity
D0N37_RS15720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0N37_RS15750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0N37_RS15755	COG1943	Transposase
D0N37_RS15760	COG0346	lactoylglutathione lyase activity
D0N37_RS15865	COG1088	dTDP-glucose 4,6-dehydratase activity
D0N37_RS15875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0N37_RS15890	COG1596	polysaccharide export
D0N37_RS15895	COG0250	Participates in transcription elongation, termination and antitermination
D0N37_RS15910	COG1216	Glycosyl transferase, family 2
D0N37_RS15910	COG1442	glycosyl transferase family 8
D0N37_RS15930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D0N37_RS15975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D0N37_RS15990	COG0500	methyltransferase
D0N37_RS16070	COG1459	type II secretion system
D0N37_RS16075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0N37_RS16110	COG0668	transmembrane transport
D0N37_RS16135	COG3590	peptidase
D0N37_RS16140	COG0494	nUDIX hydrolase
D0N37_RS16155	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D0N37_RS16160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0N37_RS16165	COG0849	cell division
D0N37_RS16170	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D0N37_RS16175	COG1181	Belongs to the D-alanine--D-alanine ligase family
D0N37_RS16180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0N37_RS16185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0N37_RS16190	COG0772	Belongs to the SEDS family
D0N37_RS16200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0N37_RS16205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0N37_RS16210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D0N37_RS16215	COG0768	penicillin binding
D0N37_RS16220	COG3116	cell division
D0N37_RS16225	COG0275	rRNA processing
D0N37_RS16230	COG2001	Belongs to the MraZ family
D0N37_RS16240	COG1785	Belongs to the alkaline phosphatase family
D0N37_RS16245	COG3263	regulation of cellular component size
D0N37_RS16260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0N37_RS16265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0N37_RS16275	COG2188	Transcriptional regulator
D0N37_RS16295	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D0N37_RS16320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0N37_RS16330	COG3954	Phosphoribulokinase
D0N37_RS16335	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D0N37_RS16340	COG1011	Hydrolase
D0N37_RS16350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0N37_RS16355	COG0557	exoribonuclease II activity
D0N37_RS16365	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
D0N37_RS16365	COG4932	domain protein
D0N37_RS16365	COG3266	domain, Protein
D0N37_RS16385	COG2197	response regulator
D0N37_RS16390	COG4585	Histidine kinase
D0N37_RS16400	COG0584	glycerophosphoryl diester phosphodiesterase
D0N37_RS16405	COG0840	transmembrane signaling receptor activity
D0N37_RS16410	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D0N37_RS16415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0N37_RS16420	COG1509	lysine 2,3-aminomutase activity
D0N37_RS16435	COG0546	phosphoglycolate phosphatase activity
D0N37_RS16495	COG0459	protein refolding
D0N37_RS16500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D0N37_RS16505	COG3030	protein affecting phage T7 exclusion by the F plasmid
D0N37_RS16510	COG1324	tolerance protein
D0N37_RS16515	COG4232	protein-disulfide reductase activity
D0N37_RS16520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D0N37_RS16525	COG0511	ligase activity, forming carbon-carbon bonds
D0N37_RS16530	COG0439	Biotin carboxylase
D0N37_RS16565	COG3421	Type III restriction
D0N37_RS16570	COG3421	Type III restriction
D0N37_RS16575	COG2189	Belongs to the N(4) N(6)-methyltransferase family
D0N37_RS16610	COG4615	Cyclic peptide transporter
D0N37_RS16650	COG1228	amidohydrolase
D0N37_RS16655	COG0405	Gamma-glutamyltransferase
D0N37_RS16670	COG0735	belongs to the Fur family
D0N37_RS16680	COG0432	Pfam Uncharacterised protein family UPF0047
D0N37_RS16690	COG0305	Participates in initiation and elongation during chromosome replication
D0N37_RS16725	COG4968	Prepilin-type N-terminal cleavage methylation domain
D0N37_RS16735	COG0359	binds to the 23S rRNA
D0N37_RS16740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D0N37_RS16745	COG2965	DNA replication, synthesis of RNA primer
D0N37_RS16750	COG0360	Binds together with S18 to 16S ribosomal RNA
D0N37_RS16780	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D0N37_RS16785	COG1162	GTPase activity
D0N37_RS16790	COG0688	phosphatidylethanolamine metabolic process
D0N37_RS16800	COG0352	thiamine-phosphate diphosphorylase activity
D0N37_RS16805	COG2022	thiamine diphosphate biosynthetic process
D0N37_RS16820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D0N37_RS16860	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D0N37_RS16865	COG1765	OsmC-like protein
D0N37_RS16875	COG1012	belongs to the aldehyde dehydrogenase family
D0N37_RS16885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0N37_RS16900	COG0180	Tryptophanyl-tRNA synthetase
D0N37_RS16910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0N37_RS16925	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0N37_RS16935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D0N37_RS16940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D0N37_RS16975	COG0527	aspartate kinase activity
D0N37_RS16975	COG0460	homoserine dehydrogenase
D0N37_RS16985	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
D0N37_RS16990	COG0281	malic enzyme
D0N37_RS16995	COG0254	rRNA binding
D0N37_RS17010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D0N37_RS17015	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D0N37_RS17025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D0N37_RS17025	COG0456	acetyltransferase
D0N37_RS17040	COG0671	phosphoesterase, PA-phosphatase related
D0N37_RS17045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D0N37_RS17050	COG0010	Belongs to the arginase family
D0N37_RS17055	COG2200	EAL domain
D0N37_RS17060	COG1228	amidohydrolase
D0N37_RS17065	COG2188	Transcriptional regulator
D0N37_RS17070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D0N37_RS17075	COG2986	histidine ammonia-lyase
D0N37_RS17080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0N37_RS17120	COG0724	RNA recognition motif
D0N37_RS17135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0N37_RS17140	COG1683	Conserved Protein
D0N37_RS17145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0N37_RS17160	COG0348	domain, Protein
D0N37_RS17195	COG3156	type II secretion system protein K
D0N37_RS17205	COG2165	general secretion pathway protein
D0N37_RS17215	COG2165	general secretion pathway protein
D0N37_RS17220	COG1459	type II secretion system
D0N37_RS17225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0N37_RS17235	COG3031	protein transport across the cell outer membrane
D0N37_RS17245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D0N37_RS17250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D0N37_RS17275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0N37_RS17280	COG2183	response to ionizing radiation
D0N37_RS17295	COG0596	Alpha beta hydrolase
D0N37_RS17300	COG1040	competence protein
D0N37_RS17310	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D0N37_RS17310	COG0316	Belongs to the HesB IscA family
D0N37_RS17320	COG0534	Mate efflux family protein
D0N37_RS17330	COG2201	protein-glutamate methylesterase activity
D0N37_RS17335	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D0N37_RS17345	COG0840	transmembrane signaling receptor activity
D0N37_RS17355	COG2198	Histidine kinase
D0N37_RS17355	COG0643	Histidine kinase
D0N37_RS17360	COG0745	RESPONSE REGULATOR receiver
D0N37_RS17370	COG1999	signal sequence binding
D0N37_RS17375	COG0109	protoheme IX farnesyltransferase activity
D0N37_RS17405	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D0N37_RS17410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0N37_RS17415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0N37_RS17425	COG3335	DDE superfamily endonuclease
D0N37_RS17450	COG0203	ribosomal protein L17
D0N37_RS17455	COG0202	RNA polymerase activity
D0N37_RS17460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D0N37_RS17465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D0N37_RS17470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0N37_RS17475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D0N37_RS17480	COG0201	protein transport
D0N37_RS17485	COG0200	Binds to the 23S rRNA
D0N37_RS17490	COG1841	ribosomal large subunit assembly
D0N37_RS17495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D0N37_RS17500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D0N37_RS17505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D0N37_RS17510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D0N37_RS17515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D0N37_RS17520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0N37_RS17525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D0N37_RS17530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D0N37_RS17575	COG4989	oxidoreductase activity
D0N37_RS17580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D0N37_RS17585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0N37_RS17595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0N37_RS17605	COG0179	Fumarylacetoacetate (FAA) hydrolase
D0N37_RS17615	COG4152	abc transporter atp-binding protein
D0N37_RS17625	COG4555	ABC transporter
D0N37_RS17640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS17645	COG0640	Transcriptional regulator
D0N37_RS17655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0N37_RS17670	COG2885	chlorophyll binding
D0N37_RS17690	COG0204	Acyl-transferase
D0N37_RS17695	COG0204	Acyl-transferase
D0N37_RS17700	COG1166	arginine decarboxylase activity
D0N37_RS17705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D0N37_RS17730	COG0537	adenosine 5'-monophosphoramidase activity
D0N37_RS17745	COG0823	Involved in the tonB-independent uptake of proteins
D0N37_RS17745	COG1506	peptidase
D0N37_RS17745	COG4946	Tricorn protease homolog
D0N37_RS17750	COG0840	transmembrane signaling receptor activity
D0N37_RS17760	COG0436	Aminotransferase
D0N37_RS17765	COG0235	Class ii aldolase
D0N37_RS17805	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D0N37_RS17825	COG2226	methyltransferase
D0N37_RS17840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0N37_RS17845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0N37_RS17850	COG0805	protein transport
D0N37_RS17885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0N37_RS17895	COG1940	carbohydrate kinase activity
D0N37_RS17900	COG2222	sugar isomerase
D0N37_RS17910	COG1349	DNA-binding transcription factor activity
D0N37_RS17935	COG3706	GGDEF domain
D0N37_RS17940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0N37_RS17965	COG0783	Belongs to the Dps family
D0N37_RS17970	COG1770	oligopeptidase
D0N37_RS17985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS18005	COG1136	(ABC) transporter
D0N37_RS18005	COG0577	efflux transmembrane transporter activity
D0N37_RS18030	COG1404	Belongs to the peptidase S8 family
D0N37_RS18045	COG5000	phosphorelay sensor kinase activity
D0N37_RS18055	COG0676	glucose-6-phosphate 1-epimerase activity
D0N37_RS18060	COG0840	transmembrane signaling receptor activity
D0N37_RS18070	COG0367	asparagine synthase
D0N37_RS18075	COG0540	Belongs to the ATCase OTCase family
D0N37_RS18125	COG0745	RESPONSE REGULATOR receiver
D0N37_RS18135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0N37_RS18145	COG0583	DNA-binding transcription factor activity
D0N37_RS18195	COG3279	Response regulator of the LytR AlgR family
D0N37_RS18210	COG3436	PFAM IS66 Orf2 family protein
D0N37_RS18220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0N37_RS18235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0N37_RS18240	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0N37_RS18240	COG0596	Alpha beta hydrolase
D0N37_RS18245	COG1181	Belongs to the D-alanine--D-alanine ligase family
D0N37_RS18250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D0N37_RS18260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0N37_RS18265	COG1349	DNA-binding transcription factor activity
D0N37_RS18300	COG1519	Transferase
D0N37_RS18305	COG0577	efflux transmembrane transporter activity
D0N37_RS18310	COG0577	efflux transmembrane transporter activity
D0N37_RS18310	COG1136	(ABC) transporter
D0N37_RS18315	COG1136	(ABC) transporter
D0N37_RS18315	COG0577	efflux transmembrane transporter activity
D0N37_RS18320	COG1566	PFAM secretion protein HlyD family protein
D0N37_RS18330	COG4191	Histidine kinase
D0N37_RS18335	COG3279	Response regulator of the LytR AlgR family
D0N37_RS18355	COG3279	Response regulator of the LytR AlgR family
D0N37_RS18360	COG0741	lytic transglycosylase activity
D0N37_RS18360	COG1388	LysM domain
D0N37_RS18410	COG1940	carbohydrate kinase activity
D0N37_RS18450	COG2366	antibiotic biosynthetic process
D0N37_RS18470	COG1136	(ABC) transporter
D0N37_RS18470	COG0577	efflux transmembrane transporter activity
D0N37_RS18535	COG3724	N-succinylarginine dihydrolase activity
D0N37_RS18545	COG0745	RESPONSE REGULATOR receiver
D0N37_RS18555	COG2977	Belongs to the P-Pant transferase superfamily
D0N37_RS18565	COG2963	transposase activity
D0N37_RS18615	COG0577	efflux transmembrane transporter activity
D0N37_RS18615	COG1136	(ABC) transporter
D0N37_RS18630	COG3279	Response regulator of the LytR AlgR family
D0N37_RS18635	COG3275	phosphorelay sensor kinase activity
D0N37_RS18655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D0N37_RS18680	COG2226	methyltransferase
D0N37_RS18685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0N37_RS18695	COG0010	Belongs to the arginase family
D0N37_RS18730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS18740	COG1028	Short-chain dehydrogenase reductase Sdr
D0N37_RS18745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0N37_RS18780	COG0367	asparagine synthase
D0N37_RS18785	COG3425	synthase
D0N37_RS18805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0N37_RS18810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D0N37_RS18815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0N37_RS18820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D0N37_RS18825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0N37_RS18830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D0N37_RS18840	COG0356	it plays a direct role in the translocation of protons across the membrane
D0N37_RS18850	COG1475	DNA binding
D0N37_RS18855	COG1192	Involved in chromosome partitioning
D0N37_RS18860	COG0357	Ribosomal RNA small subunit methyltransferase G
D0N37_RS18865	COG0445	tRNA wobble uridine modification
D0N37_RS18870	COG0716	FMN binding
D0N37_RS18885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D0N37_RS18890	COG0745	RESPONSE REGULATOR receiver
D0N37_RS18905	COG4232	protein-disulfide reductase activity
D0N37_RS18915	COG0706	membrane insertase activity
D0N37_RS18920	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0N37_RS18925	COG0594	ribonuclease P activity
D0N37_RS18930	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D0N37_RS18960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0N37_RS19020	COG2205	protein histidine kinase activity
D0N37_RS19025	COG0745	RESPONSE REGULATOR receiver
D0N37_RS19030	COG0569	domain protein
D0N37_RS19035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0N37_RS19040	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0N37_RS19075	COG4771	TonB-dependent receptor
D0N37_RS19090	COG0640	Transcriptional regulator
D0N37_RS19095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0N37_RS19110	COG1609	Transcriptional regulator
D0N37_RS19120	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D0N37_RS19165	COG2204	response regulator
D0N37_RS19225	COG0295	cytidine deaminase activity
D0N37_RS19230	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D0N37_RS19240	COG0010	Belongs to the arginase family
D0N37_RS19250	COG4628	conserved protein (DUF2132)
D0N37_RS19265	COG0625	glutathione transferase activity
D0N37_RS19270	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D0N37_RS19305	COG0737	Belongs to the 5'-nucleotidase family
D0N37_RS19320	COG1025	Belongs to the peptidase M16 family
D0N37_RS19335	COG3008	intermembrane lipid transfer
D0N37_RS19335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D0N37_RS19340	COG2995	paraquat-inducible protein a
D0N37_RS19350	COG0443	Heat shock 70 kDa protein
D0N37_RS19355	COG0484	heat shock protein binding
D0N37_RS19360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0N37_RS19365	COG1960	acyl-CoA dehydrogenase activity
D0N37_RS19400	COG4771	TonB-dependent receptor
D0N37_RS19420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D0N37_RS19425	COG0254	rRNA binding
D0N37_RS19440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0N37_RS19445	COG0513	Belongs to the DEAD box helicase family
D0N37_RS19470	COG3547	Transposase (IS116 IS110 IS902 family)
D0N37_RS19495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D0N37_RS19505	COG0778	Nitroreductase
D0N37_RS19520	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D0N37_RS19525	COG0415	Belongs to the DNA photolyase family
D0N37_RS19545	COG1234	tRNA 3'-trailer cleavage
D0N37_RS19590	COG3138	arginine N-succinyltransferase
D0N37_RS19595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0N37_RS19615	COG1640	4-alpha-glucanotransferase
D0N37_RS19620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D0N37_RS19630	COG0058	SHG alpha-glucan phosphorylase activity
D0N37_RS19640	COG0297	glycogen (starch) synthase activity
D0N37_RS19645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0N37_RS19650	COG2311	Membrane
D0N37_RS19670	COG2894	cell division
D0N37_RS19675	COG0850	regulation of cytokinetic process
D0N37_RS19680	COG3100	YcgL domain-containing protein
D0N37_RS19685	COG2951	lytic endotransglycosylase activity
D0N37_RS19690	COG1294	oxidase, subunit
D0N37_RS19695	COG1271	oxidase subunit
D0N37_RS19715	COG3706	GGDEF domain
D0N37_RS19720	COG1288	antiporter activity
D0N37_RS19725	COG5001	Diguanylate cyclase
D0N37_RS19725	COG3300	MHYT domain
D0N37_RS19730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D0N37_RS19735	COG0840	transmembrane signaling receptor activity
D0N37_RS19755	COG0745	RESPONSE REGULATOR receiver
D0N37_RS19795	COG3706	GGDEF domain
D0N37_RS19800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0N37_RS19810	COG3895	Periplasmic Protein
D0N37_RS19820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0N37_RS19825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0N37_RS19845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D0N37_RS19860	COG0300	oxidoreductase activity
D0N37_RS19870	COG0415	Belongs to the DNA photolyase family
D0N37_RS19885	COG1595	DNA-templated transcription, initiation
D0N37_RS19900	COG0583	DNA-binding transcription factor activity
D0N37_RS19905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0N37_RS19910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0N37_RS19915	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D0N37_RS19920	COG0318	PFAM AMP-dependent synthetase and ligase
D0N37_RS19925	COG0596	Alpha beta hydrolase
D0N37_RS19930	COG1785	Belongs to the alkaline phosphatase family
D0N37_RS19945	COG1199	ATP-dependent helicase activity
D0N37_RS19965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D0N37_RS19970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0N37_RS19975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0N37_RS19980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D0N37_RS19980	COG0131	Imidazoleglycerol-phosphate dehydratase
D0N37_RS19985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D0N37_RS19990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D0N37_RS19995	COG0107	imidazoleglycerol-phosphate synthase activity
D0N37_RS20000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D0N37_RS20000	COG0140	phosphoribosyl-ATP diphosphatase activity
D0N37_RS20035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0N37_RS20050	COG0473	3-isopropylmalate dehydrogenase activity
D0N37_RS20060	COG0028	Belongs to the TPP enzyme family
D0N37_RS20085	COG0840	transmembrane signaling receptor activity
D0N37_RS20115	COG0848	biopolymer transport protein
D0N37_RS20120	COG0811	peptide transport
D0N37_RS20125	COG0811	peptide transport
D0N37_RS20145	COG3537	Alpha-1,2-mannosidase
D0N37_RS20165	COG2983	Belongs to the UPF0260 family
D0N37_RS20175	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0N37_RS20190	COG0514	ATP-dependent DNA helicase (RecQ)
D0N37_RS20220	COG0247	lactate metabolic process
D0N37_RS20220	COG0277	FAD linked oxidase domain protein
D0N37_RS20230	COG0574	Belongs to the PEP-utilizing enzyme family
D0N37_RS20230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0N37_RS20235	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D0N37_RS20255	COG1192	Involved in chromosome partitioning
D0N37_RS20265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0N37_RS20285	COG0745	RESPONSE REGULATOR receiver
D0N37_RS20290	COG1322	Protein conserved in bacteria
D0N37_RS20305	COG2205	protein histidine kinase activity
D0N37_RS20315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D0N37_RS20320	COG1335	isochorismatase
D0N37_RS20330	COG3547	Transposase (IS116 IS110 IS902 family)
D0N37_RS20345	COG1476	TRANSCRIPTIONal
D0N37_RS20355	COG1309	transcriptional regulator
D0N37_RS20360	COG1012	belongs to the aldehyde dehydrogenase family
D0N37_RS20395	COG4771	TonB-dependent receptor
D0N37_RS20480	COG0789	Transcriptional regulator
D0N37_RS20490	COG1858	cytochrome C peroxidase
D0N37_RS20560	COG4181	ATPase activity
D0N37_RS20635	COG3040	lipid binding
D0N37_RS20675	COG1573	uracil-dna glycosylase
D0N37_RS20700	COG1131	(ABC) transporter
D0N37_RS20710	COG1741	Belongs to the pirin family
D0N37_RS20715	COG0435	Glutathione S-transferase
D0N37_RS20740	COG1971	Probably functions as a manganese efflux pump
D0N37_RS20745	COG4191	Histidine kinase
D0N37_RS20760	COG0577	efflux transmembrane transporter activity
D0N37_RS20760	COG1136	(ABC) transporter
D0N37_RS20765	COG1136	(ABC) transporter
D0N37_RS20765	COG0577	efflux transmembrane transporter activity
D0N37_RS20775	COG0678	peroxiredoxin activity
D0N37_RS20775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0N37_RS20825	COG1234	tRNA 3'-trailer cleavage
D0N37_RS20840	COG1309	transcriptional regulator
D0N37_RS20845	COG1132	(ABC) transporter
D0N37_RS20850	COG0454	-acetyltransferase
D0N37_RS20860	COG1505	serine-type exopeptidase activity
D0N37_RS20905	COG0583	DNA-binding transcription factor activity
D0N37_RS20925	COG0745	RESPONSE REGULATOR receiver
D0N37_RS20935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0N37_RS20940	COG1136	(ABC) transporter
D0N37_RS20945	COG1136	(ABC) transporter
D0N37_RS20945	COG0577	efflux transmembrane transporter activity
D0N37_RS20975	COG1737	Transcriptional regulator
D0N37_RS20995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0N37_RS21020	COG2205	protein histidine kinase activity
D0N37_RS21025	COG0745	RESPONSE REGULATOR receiver
D0N37_RS21035	COG3713	MltA-interacting MipA family protein
D0N37_RS21050	COG0745	RESPONSE REGULATOR receiver
D0N37_RS21110	COG0217	transcriptional regulatory protein
D0N37_RS21180	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0N37_RS21195	COG0583	DNA-binding transcription factor activity
D0N37_RS21205	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D0N37_RS21240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0N37_RS21250	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D0N37_RS21255	COG4336	lyase activity
D0N37_RS21290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D0N37_RS21320	COG1278	Cold shock
D0N37_RS21330	COG0300	oxidoreductase activity
D0N37_RS21335	COG5433	transposase activity
D0N37_RS21340	COG3547	Transposase (IS116 IS110 IS902 family)
D0N37_RS21370	COG2819	hydrolase of the alpha beta superfamily
D0N37_RS21430	COG4771	TonB-dependent receptor
D0N37_RS21450	COG1063	alcohol dehydrogenase
D0N37_RS21465	COG0318	PFAM AMP-dependent synthetase and ligase
D0N37_RS21510	COG4633	Protein conserved in bacteria
D0N37_RS21530	COG1278	Cold shock
D0N37_RS21545	COG2824	Alkylphosphonate utilization operon protein PhnA
D0N37_RS21595	COG0251	oxidation-reduction process
D0N37_RS21610	COG1802	Transcriptional regulator
D0N37_RS21615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D0N37_RS21620	COG0372	Belongs to the citrate synthase family
D0N37_RS21625	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D0N37_RS21630	COG2828	Protein conserved in bacteria
D0N37_RS21725	COG1136	(ABC) transporter
D0N37_RS21725	COG0577	efflux transmembrane transporter activity
D0N37_RS21730	COG1136	(ABC) transporter
D0N37_RS21730	COG0577	efflux transmembrane transporter activity
D0N37_RS21735	COG2204	response regulator
D0N37_RS21755	COG2207	Transcriptional regulator
D0N37_RS21760	COG5001	Diguanylate cyclase
D0N37_RS21785	COG1506	peptidase
D0N37_RS21785	COG4946	Tricorn protease homolog
D0N37_RS21785	COG0823	Involved in the tonB-independent uptake of proteins
D0N37_RS21835	COG0730	response to heat
D0N37_RS21875	COG0346	lactoylglutathione lyase activity
D0N37_RS21885	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D0N37_RS21890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0N37_RS21895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0N37_RS21905	COG0811	peptide transport
D0N37_RS21910	COG0848	biopolymer transport protein
D0N37_RS21920	COG3720	iron ion transport
D0N37_RS21965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0N37_RS22030	COG2207	Transcriptional regulator
D0N37_RS22035	COG0823	Involved in the tonB-independent uptake of proteins
D0N37_RS22035	COG1506	peptidase
D0N37_RS22060	COG4946	Tricorn protease homolog
D0N37_RS22060	COG0793	Belongs to the peptidase S41A family
D0N37_RS22080	COG1136	(ABC) transporter
D0N37_RS22100	COG3437	response regulator, receiver
D0N37_RS22125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0N37_RS22150	COG1404	Belongs to the peptidase S8 family
D0N37_RS22175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0N37_RS22175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0N37_RS22200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0N37_RS22205	COG0572	uridine kinase
D0N37_RS22210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D0N37_RS22215	COG0813	purine-nucleoside phosphorylase activity
D0N37_RS22225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0N37_RS22250	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0N37_RS22255	COG2197	response regulator
D0N37_RS22260	COG4585	Histidine kinase
D0N37_RS22265	COG0840	transmembrane signaling receptor activity
D0N37_RS22280	COG0583	DNA-binding transcription factor activity
D0N37_RS22295	COG1285	pathogenesis
D0N37_RS22315	COG0454	-acetyltransferase
D0N37_RS22315	COG0456	acetyltransferase
D0N37_RS22320	COG0598	Magnesium transport protein CorA
D0N37_RS22385	COG1979	alcohol dehydrogenase
D0N37_RS22400	COG0501	Belongs to the peptidase M48B family
D0N37_RS22410	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0N37_RS22425	COG1794	racemase activity, acting on amino acids and derivatives
D0N37_RS22435	COG4774	siderophore transport
D0N37_RS22440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0N37_RS22440	COG2207	Transcriptional regulator
D0N37_RS22445	COG1404	Belongs to the peptidase S8 family
D0N37_RS22525	COG0789	Transcriptional regulator
D0N37_RS22535	COG1104	cysteine desulfurase activity
D0N37_RS22595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0N37_RS22615	COG1404	Belongs to the peptidase S8 family
D0N37_RS22660	COG2814	Major facilitator Superfamily
D0N37_RS22685	COG1280	lysine exporter protein (LysE YggA)
D0N37_RS22705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D0N37_RS22730	COG0693	protein deglycase activity
D0N37_RS22755	COG1278	Cold shock
D0N37_RS22840	COG3706	GGDEF domain
D0N37_RS22855	COG1770	oligopeptidase
D0N37_RS22860	COG0840	transmembrane signaling receptor activity
D0N37_RS22870	COG2204	response regulator
D0N37_RS22880	COG2205	protein histidine kinase activity
D0N37_RS22910	COG0071	Belongs to the small heat shock protein (HSP20) family
D0N37_RS22935	COG0823	Involved in the tonB-independent uptake of proteins
D0N37_RS22935	COG4946	Tricorn protease homolog
D0N37_RS22935	COG1506	peptidase
D0N37_RS22950	COG5433	transposase activity
D0N37_RS22990	COG1609	Transcriptional regulator
D0N37_RS23065	COG2203	Gaf domain
D0N37_RS23065	COG2199	diguanylate cyclase activity
D0N37_RS23080	COG3634	alkyl hydroperoxide reductase activity
D0N37_RS23090	COG0527	aspartate kinase activity
D0N37_RS23090	COG0460	homoserine dehydrogenase
D0N37_RS23130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0N37_RS23155	COG3251	PFAM MbtH domain protein
D0N37_RS23180	COG3397	chitin binding
D0N37_RS23205	COG4681	YaeQ
D0N37_RS23275	COG0577	efflux transmembrane transporter activity
D0N37_RS23275	COG1136	(ABC) transporter
D0N37_RS23385	COG1051	belongs to the nudix hydrolase family
D0N37_RS23425	COG4771	TonB-dependent receptor
D0N37_RS23480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D0N37_RS23490	COG1104	cysteine desulfurase activity
D0N37_RS23525	COG0583	DNA-binding transcription factor activity
D0N37_RS23530	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D0N37_RS23540	COG4206	TonB-dependent receptor
D0N37_RS23555	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D0N37_RS23575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D0N37_RS23610	COG1472	Belongs to the glycosyl hydrolase 3 family
D0N37_RS23625	COG1609	Transcriptional regulator
D0N37_RS23640	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D0N37_RS23660	COG1104	cysteine desulfurase activity
D0N37_RS23685	COG5001	Diguanylate cyclase
D0N37_RS23685	COG2203	Gaf domain
D0N37_RS23685	COG4251	negative regulation of phosphorylation
D0N37_RS23685	COG3706	GGDEF domain
D0N37_RS23705	COG0784	Response regulator, receiver
D0N37_RS23705	COG2205	protein histidine kinase activity
D0N37_RS23715	COG2906	2 iron, 2 sulfur cluster binding
D0N37_RS23725	COG2193	ferroxidase activity
D0N37_RS23745	COG1230	cation diffusion facilitator family transporter
D0N37_RS23755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0N37_RS23765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0N37_RS23775	COG1435	thymidine kinase activity
D0N37_RS23780	COG3437	response regulator, receiver
D0N37_RS23780	COG0784	Response regulator, receiver
D0N37_RS23810	COG0612	Peptidase, M16
D0N37_RS23830	COG1136	(ABC) transporter
D0N37_RS23835	COG0577	efflux transmembrane transporter activity
D0N37_RS23835	COG1136	(ABC) transporter
D0N37_RS23845	COG2204	response regulator
D0N37_RS23850	COG3852	Histidine kinase
D0N37_RS23860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0N37_RS23865	COG1017	nitric oxide dioxygenase activity
D0N37_RS23865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0N37_RS23890	COG2193	ferroxidase activity
D0N37_RS23900	COG0784	Response regulator, receiver
D0N37_RS23900	COG2205	protein histidine kinase activity
D0N37_RS23900	COG5002	protein histidine kinase activity
D0N37_RS23945	COG0840	transmembrane signaling receptor activity
D0N37_RS23950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0N37_RS23970	COG1115	amino acid carrier protein
D0N37_RS23995	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
D0N37_RS24005	COG0457	Tetratricopeptide repeat
D0N37_RS24010	COG4771	TonB-dependent receptor
D0N37_RS24025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0N37_RS24030	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0N37_RS24035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0N37_RS24045	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D0N37_RS24080	COG0572	uridine kinase
D0N37_RS24095	COG1595	DNA-templated transcription, initiation
D0N37_RS24105	COG2304	oxidoreductase activity
D0N37_RS24130	COG0183	Belongs to the thiolase family
D0N37_RS24135	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0N37_RS24135	COG1024	Enoyl-CoA hydratase
D0N37_RS24150	COG3101	peptidyl-lysine hydroxylation
D0N37_RS24180	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D0N37_RS24250	COG1944	ATP diphosphatase activity