locus-tag	class	description
JG479_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JG479_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JG479_RS00020	COG0187	DNA topoisomerase II activity
JG479_RS00025	COG0752	glycyl-tRNA synthetase alpha subunit
JG479_RS00030	COG0751	glycine-tRNA ligase activity
JG479_RS00040	COG1943	Transposase
JG479_RS00045	COG0425	Belongs to the sulfur carrier protein TusA family
JG479_RS00050	COG0183	Belongs to the thiolase family
JG479_RS00055	COG1024	Enoyl-CoA hydratase
JG479_RS00055	COG1250	3-hydroxyacyl-CoA dehydrogenase
JG479_RS00060	COG0741	lytic transglycosylase activity
JG479_RS00065	COG0006	proline dipeptidase activity
JG479_RS00070	COG1739	Uncharacterized protein family UPF0029
JG479_RS00075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG479_RS00100	COG0569	domain protein
JG479_RS00105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JG479_RS00105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JG479_RS00110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JG479_RS00115	COG0242	peptide deformylase activity
JG479_RS00125	COG0758	DNA mediated transformation
JG479_RS00130	COG2922	Belongs to the Smg family
JG479_RS00135	COG0551	DNA topoisomerase type I activity
JG479_RS00140	COG0009	L-threonylcarbamoyladenylate synthase
JG479_RS00145	COG0408	coproporphyrinogen oxidase activity
JG479_RS00150	COG2346	COG2346, Truncated hemoglobins
JG479_RS00155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JG479_RS00165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JG479_RS00205	COG5001	Diguanylate cyclase
JG479_RS00220	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JG479_RS00290	COG2205	protein histidine kinase activity
JG479_RS00290	COG0784	Response regulator, receiver
JG479_RS00295	COG1522	sequence-specific DNA binding
JG479_RS00305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JG479_RS00330	COG1597	lipid kinase activity
JG479_RS00340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG479_RS00355	COG0386	Belongs to the glutathione peroxidase family
JG479_RS00365	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JG479_RS00375	COG3397	chitin binding
JG479_RS00380	COG1770	oligopeptidase
JG479_RS00395	COG4771	TonB-dependent receptor
JG479_RS00400	COG0783	Belongs to the Dps family
JG479_RS00415	COG4681	YaeQ
JG479_RS00430	COG4565	transcriptional regulatory protein
JG479_RS00435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JG479_RS00445	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JG479_RS00460	COG4251	negative regulation of phosphorylation
JG479_RS00460	COG3706	GGDEF domain
JG479_RS00460	COG5001	Diguanylate cyclase
JG479_RS00460	COG2203	Gaf domain
JG479_RS00465	COG0084	hydrolase, TatD family'
JG479_RS00475	COG0805	protein transport
JG479_RS00480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JG479_RS00485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JG479_RS00500	COG2226	methyltransferase
JG479_RS00515	COG0069	glutamate synthase activity
JG479_RS00520	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JG479_RS00525	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JG479_RS00540	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
JG479_RS00545	COG0235	Class ii aldolase
JG479_RS00550	COG0436	Aminotransferase
JG479_RS00575	COG0537	adenosine 5'-monophosphoramidase activity
JG479_RS00590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JG479_RS00600	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JG479_RS00625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JG479_RS00635	COG3089	Belongs to the UPF0270 family
JG479_RS00640	COG0429	hydrolase of the alpha beta-hydrolase fold
JG479_RS00650	COG0488	(ABC) transporter
JG479_RS00655	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JG479_RS00660	COG2900	Belongs to the SlyX family
JG479_RS00670	COG0545	Peptidyl-prolyl cis-trans isomerase
JG479_RS00675	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JG479_RS00680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JG479_RS00685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG479_RS00700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JG479_RS00705	COG0473	3-isopropylmalate dehydrogenase activity
JG479_RS00710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JG479_RS00715	COG0066	3-isopropylmalate dehydratase activity
JG479_RS00725	COG2356	endonuclease I
JG479_RS00730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JG479_RS00735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG479_RS00755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JG479_RS00780	COG2204	response regulator
JG479_RS00785	COG3852	Histidine kinase
JG479_RS00795	COG0174	glutamine synthetase
JG479_RS00800	COG1217	gtp-binding protein TYPA
JG479_RS00820	COG1295	ribonuclease BN
JG479_RS00825	COG1490	D-aminoacyl-tRNA deacylase activity
JG479_RS00835	COG0456	acetyltransferase
JG479_RS00840	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
JG479_RS00850	COG0019	diaminopimelate decarboxylase activity
JG479_RS00860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JG479_RS00870	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JG479_RS00875	COG2885	chlorophyll binding
JG479_RS00880	COG1049	propionate catabolic process, 2-methylcitrate cycle
JG479_RS00890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JG479_RS00925	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JG479_RS00935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JG479_RS00940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG479_RS00945	COG1522	sequence-specific DNA binding
JG479_RS00950	COG2502	aspartate--ammonia ligase
JG479_RS00965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JG479_RS00970	COG1758	RNA polymerase activity
JG479_RS00975	COG0194	GDP metabolic process
JG479_RS00980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JG479_RS00980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JG479_RS00985	COG0346	lactoylglutathione lyase activity
JG479_RS00995	COG0459	protein refolding
JG479_RS01000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JG479_RS01005	COG3030	protein affecting phage T7 exclusion by the F plasmid
JG479_RS01010	COG1324	tolerance protein
JG479_RS01015	COG4232	protein-disulfide reductase activity
JG479_RS01020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JG479_RS01025	COG0511	ligase activity, forming carbon-carbon bonds
JG479_RS01030	COG0439	Biotin carboxylase
JG479_RS01035	COG2186	Transcriptional regulator
JG479_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
JG479_RS01045	COG3734	2-keto-3-deoxy-galactonokinase
JG479_RS01050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JG479_RS01070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JG479_RS01080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JG479_RS01085	COG0300	oxidoreductase activity
JG479_RS01100	COG0583	DNA-binding transcription factor activity
JG479_RS01120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JG479_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
JG479_RS01140	COG1765	OsmC-like protein
JG479_RS01145	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JG479_RS01155	COG0814	amino acid
JG479_RS01170	COG1218	3'(2'),5'-bisphosphate nucleotidase
JG479_RS01175	COG0529	Catalyzes the synthesis of activated sulfate
JG479_RS01180	COG3273	potassium ion transport
JG479_RS01180	COG0471	metal ion transport
JG479_RS01185	COG2895	sulfate adenylyltransferase (ATP) activity
JG479_RS01190	COG0175	sulfate reduction
JG479_RS01195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JG479_RS01195	COG1648	precorrin-2 dehydrogenase activity
JG479_RS01200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JG479_RS01215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG479_RS01220	COG0250	Participates in transcription elongation, termination and antitermination
JG479_RS01225	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JG479_RS01230	COG0081	regulation of translation
JG479_RS01235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JG479_RS01240	COG0222	ribosome binding
JG479_RS01245	COG0085	RNA polymerase activity
JG479_RS01250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JG479_RS01255	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JG479_RS01260	COG0049	tRNA binding
JG479_RS01265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JG479_RS01270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JG479_RS01275	COG1561	YicC-like family, N-terminal region
JG479_RS01280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JG479_RS01285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JG479_RS01290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JG479_RS01315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JG479_RS01320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JG479_RS01325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JG479_RS01330	COG3031	protein transport across the cell outer membrane
JG479_RS01340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JG479_RS01345	COG1459	type II secretion system
JG479_RS01350	COG2165	general secretion pathway protein
JG479_RS01360	COG2165	general secretion pathway protein
JG479_RS01370	COG3156	type II secretion system protein K
JG479_RS01410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JG479_RS01425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JG479_RS01435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JG479_RS01440	COG0724	RNA recognition motif
JG479_RS01485	COG0784	Response regulator, receiver
JG479_RS01485	COG2205	protein histidine kinase activity
JG479_RS01485	COG5002	protein histidine kinase activity
JG479_RS01490	COG1119	ATPase activity
JG479_RS01510	COG1368	sulfuric ester hydrolase activity
JG479_RS01515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JG479_RS01520	COG2194	sulfuric ester hydrolase activity
JG479_RS01535	COG0129	dihydroxy-acid dehydratase activity
JG479_RS01555	COG0288	reversible hydration of carbon dioxide
JG479_RS01560	COG0702	epimerase
JG479_RS01585	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JG479_RS01590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG479_RS01590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG479_RS01605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JG479_RS01625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JG479_RS01635	COG0312	modulator of DNA gyrase
JG479_RS01645	COG3590	peptidase
JG479_RS01655	COG0494	nUDIX hydrolase
JG479_RS01660	COG0653	protein targeting
JG479_RS01670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JG479_RS01680	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JG479_RS01690	COG1228	amidohydrolase
JG479_RS01705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JG479_RS01710	COG0671	phosphoesterase, PA-phosphatase related
JG479_RS01730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JG479_RS01735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JG479_RS01745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JG479_RS01750	COG0254	rRNA binding
JG479_RS01755	COG0281	malic enzyme
JG479_RS01760	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
JG479_RS01765	COG0626	cystathionine gamma-synthase activity
JG479_RS01770	COG0527	aspartate kinase activity
JG479_RS01770	COG0460	homoserine dehydrogenase
JG479_RS01775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JG479_RS01805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JG479_RS01810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JG479_RS01820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JG479_RS01835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JG479_RS01845	COG0180	Tryptophanyl-tRNA synthetase
JG479_RS01865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JG479_RS01870	COG2814	Major facilitator Superfamily
JG479_RS01880	COG0789	Transcriptional regulator
JG479_RS01935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JG479_RS01960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JG479_RS02005	COG0629	single-stranded DNA binding
JG479_RS02010	COG0784	Response regulator, receiver
JG479_RS02010	COG2205	protein histidine kinase activity
JG479_RS02010	COG5002	protein histidine kinase activity
JG479_RS02015	COG0431	NADPH-dependent FMN reductase
JG479_RS02020	COG0798	PFAM Bile acid sodium symporter
JG479_RS02030	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JG479_RS02060	COG3267	Type II secretory pathway component ExeA
JG479_RS02060	COG3409	Peptidoglycan-binding domain 1 protein
JG479_RS02070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JG479_RS02075	COG1459	type II secretion system
JG479_RS02085	COG2165	general secretion pathway protein
JG479_RS02090	COG4968	Prepilin-type N-terminal cleavage methylation domain
JG479_RS02120	COG1077	Cell shape determining protein MreB Mrl
JG479_RS02125	COG1792	Involved in formation and maintenance of cell shape
JG479_RS02130	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JG479_RS02135	COG0424	maF-like protein
JG479_RS02140	COG1530	ribonuclease E activity
JG479_RS02145	COG3164	Protein of unknown function
JG479_RS02150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JG479_RS02155	COG0312	modulator of DNA gyrase
JG479_RS02160	COG0668	transmembrane transport
JG479_RS02170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG479_RS02180	COG0339	signal peptide processing
JG479_RS02190	COG0742	ribosomal rna small subunit methyltransferase
JG479_RS02195	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JG479_RS02205	COG1104	cysteine desulfurase activity
JG479_RS02210	COG0822	iron-sulfur transferase activity
JG479_RS02215	COG0316	Belongs to the HesB IscA family
JG479_RS02220	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JG479_RS02225	COG0443	Heat shock 70 kDa protein
JG479_RS02240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JG479_RS02250	COG1234	tRNA 3'-trailer cleavage
JG479_RS02275	COG0668	transmembrane transport
JG479_RS02280	COG3137	Salt-induced outer membrane protein
JG479_RS02295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JG479_RS02310	COG0778	Nitroreductase
JG479_RS02320	COG1216	Glycosyl transferase, family 2
JG479_RS02320	COG0463	Glycosyl transferase, family 2
JG479_RS02330	COG0438	transferase activity, transferring glycosyl groups
JG479_RS02330	COG0297	glycogen (starch) synthase activity
JG479_RS02340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JG479_RS02345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG479_RS02395	COG0463	Glycosyl transferase, family 2
JG479_RS02520	COG1216	Glycosyl transferase, family 2
JG479_RS02520	COG0438	transferase activity, transferring glycosyl groups
JG479_RS02535	COG0175	sulfate reduction
JG479_RS02540	COG2895	sulfate adenylyltransferase (ATP) activity
JG479_RS02545	COG3273	potassium ion transport
JG479_RS02545	COG0471	metal ion transport
JG479_RS02550	COG0529	Catalyzes the synthesis of activated sulfate
JG479_RS02560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JG479_RS02575	COG1943	Transposase
JG479_RS02585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JG479_RS02590	COG2967	ApaG domain
JG479_RS02595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JG479_RS02600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JG479_RS02605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG479_RS02610	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JG479_RS02625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JG479_RS02635	COG0564	pseudouridine synthase activity
JG479_RS02640	COG1187	pseudouridine synthase activity
JG479_RS02645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JG479_RS02660	COG0848	biopolymer transport protein
JG479_RS02665	COG0811	peptide transport
JG479_RS02680	COG4774	siderophore transport
JG479_RS02685	COG3128	pkhd-type hydroxylase
JG479_RS02690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JG479_RS02710	COG1509	lysine 2,3-aminomutase activity
JG479_RS02715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JG479_RS02720	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JG479_RS02725	COG1629	transport
JG479_RS02725	COG4774	siderophore transport
JG479_RS02740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JG479_RS02755	COG2022	thiamine diphosphate biosynthetic process
JG479_RS02760	COG0352	thiamine-phosphate diphosphorylase activity
JG479_RS02765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JG479_RS02770	COG0688	phosphatidylethanolamine metabolic process
JG479_RS02780	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JG479_RS02810	COG0735	belongs to the Fur family
JG479_RS02815	COG2095	MarC family integral membrane protein
JG479_RS02825	COG1842	Phage shock protein A
JG479_RS02865	COG3300	MHYT domain
JG479_RS02865	COG5001	Diguanylate cyclase
JG479_RS02870	COG1032	radical SAM domain protein
JG479_RS02875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG479_RS02880	COG2239	Acts as a magnesium transporter
JG479_RS02885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JG479_RS02890	COG1660	Displays ATPase and GTPase activities
JG479_RS02905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JG479_RS02910	COG1137	ATPase activity
JG479_RS02925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JG479_RS02940	COG1127	ABC transporter
JG479_RS02945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JG479_RS02950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JG479_RS02955	COG2854	intermembrane phospholipid transfer
JG479_RS02960	COG3113	response to antibiotic
JG479_RS02965	COG5007	Belongs to the BolA IbaG family
JG479_RS02970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JG479_RS02980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JG479_RS02990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JG479_RS02995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JG479_RS03000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JG479_RS03005	COG0723	plastoquinol--plastocyanin reductase activity
JG479_RS03010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JG479_RS03015	COG2857	Cytochrome c1
JG479_RS03020	COG0625	glutathione transferase activity
JG479_RS03025	COG2969	positive regulation of protein catabolic process
JG479_RS03030	COG2823	Periplasmic or secreted lipoprotein
JG479_RS03040	COG0792	nuclease activity
JG479_RS03045	COG3107	peptidoglycan biosynthetic process
JG479_RS03050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JG479_RS03065	COG1295	ribonuclease BN
JG479_RS03080	COG1741	Belongs to the pirin family
JG479_RS03085	COG0435	Glutathione S-transferase
JG479_RS03105	COG2001	Belongs to the MraZ family
JG479_RS03110	COG0275	rRNA processing
JG479_RS03115	COG3116	cell division
JG479_RS03120	COG0768	penicillin binding
JG479_RS03125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JG479_RS03130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JG479_RS03135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JG479_RS03140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JG479_RS03145	COG0772	Belongs to the SEDS family
JG479_RS03150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JG479_RS03155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JG479_RS03160	COG1181	Belongs to the D-alanine--D-alanine ligase family
JG479_RS03165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JG479_RS03170	COG0849	cell division
JG479_RS03175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JG479_RS03180	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JG479_RS03185	COG1011	Hydrolase
JG479_RS03195	COG3954	Phosphoribulokinase
JG479_RS03225	COG0625	glutathione transferase activity
JG479_RS03240	COG1247	-acetyltransferase
JG479_RS03245	COG2205	protein histidine kinase activity
JG479_RS03245	COG2202	Pas domain
JG479_RS03255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JG479_RS03260	COG0840	transmembrane signaling receptor activity
JG479_RS03265	COG0584	glycerophosphoryl diester phosphodiesterase
JG479_RS03280	COG4585	Histidine kinase
JG479_RS03285	COG2197	response regulator
JG479_RS03290	COG1024	Enoyl-CoA hydratase
JG479_RS03295	COG0557	exoribonuclease II activity
JG479_RS03300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG479_RS03305	COG4774	siderophore transport
JG479_RS03310	COG0583	DNA-binding transcription factor activity
JG479_RS03320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JG479_RS03325	COG0509	glycine decarboxylation via glycine cleavage system
JG479_RS03330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JG479_RS03330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JG479_RS03345	COG1204	response to ionizing radiation
JG479_RS03390	COG4572	Cation transport regulator
JG479_RS03410	COG2205	protein histidine kinase activity
JG479_RS03410	COG0784	Response regulator, receiver
JG479_RS03440	COG0625	glutathione transferase activity
JG479_RS03455	COG0783	Belongs to the Dps family
JG479_RS03465	COG0754	glutathionylspermidine amidase activity
JG479_RS03470	COG0668	transmembrane transport
JG479_RS03475	COG0753	catalase activity
JG479_RS03480	COG3791	Glutathione-dependent formaldehyde-activating
JG479_RS03520	COG4771	TonB-dependent receptor
JG479_RS03525	COG0583	DNA-binding transcription factor activity
JG479_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
JG479_RS03540	COG0583	DNA-binding transcription factor activity
JG479_RS03560	COG2807	transmembrane transport
JG479_RS03565	COG2207	Transcriptional regulator
JG479_RS03610	COG1012	belongs to the aldehyde dehydrogenase family
JG479_RS03615	COG0494	nUDIX hydrolase
JG479_RS03620	COG2204	response regulator
JG479_RS03630	COG4251	negative regulation of phosphorylation
JG479_RS03635	COG0784	Response regulator, receiver
JG479_RS03640	COG0784	Response regulator, receiver
JG479_RS03640	COG2205	protein histidine kinase activity
JG479_RS03645	COG0179	Fumarylacetoacetate (FAA) hydrolase
JG479_RS03655	COG0667	Aldo Keto reductase
JG479_RS03665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JG479_RS03670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JG479_RS03675	COG0840	transmembrane signaling receptor activity
JG479_RS03705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JG479_RS03730	COG2205	protein histidine kinase activity
JG479_RS03740	COG2204	response regulator
JG479_RS03755	COG0617	tRNA 3'-terminal CCA addition
JG479_RS03765	COG0642	Histidine kinase
JG479_RS03770	COG0745	RESPONSE REGULATOR receiver
JG479_RS03790	COG0697	spore germination
JG479_RS03795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JG479_RS03805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JG479_RS03830	COG0513	Belongs to the DEAD box helicase family
JG479_RS03835	COG2199	diguanylate cyclase activity
JG479_RS03835	COG2203	Gaf domain
JG479_RS03850	COG0612	Peptidase, M16
JG479_RS03855	COG1045	serine acetyltransferase
JG479_RS03865	COG1570	exodeoxyribonuclease VII activity
JG479_RS03870	COG0517	IMP dehydrogenase activity
JG479_RS03870	COG0516	GMP reductase activity
JG479_RS03875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JG479_RS03875	COG0519	Catalyzes the synthesis of GMP from XMP
JG479_RS03895	COG2205	protein histidine kinase activity
JG479_RS03895	COG0784	Response regulator, receiver
JG479_RS03920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JG479_RS03925	COG0018	arginyl-trna synthetase
JG479_RS03930	COG0259	pyridoxamine-phosphate oxidase activity
JG479_RS03935	COG0084	hydrolase, TatD family'
JG479_RS03945	COG0560	Phosphoserine phosphatase
JG479_RS03970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JG479_RS03975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JG479_RS03985	COG0137	argininosuccinate synthase activity
JG479_RS03990	COG0165	Argininosuccinate lyase
JG479_RS03990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JG479_RS04015	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JG479_RS04025	COG0301	tRNA thio-modification
JG479_RS04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG479_RS04040	COG1666	GTP binding
JG479_RS04050	COG4206	TonB-dependent receptor
JG479_RS04060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG479_RS04065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS04090	COG3409	Peptidoglycan-binding domain 1 protein
JG479_RS04090	COG3267	Type II secretory pathway component ExeA
JG479_RS04115	COG5001	Diguanylate cyclase
JG479_RS04115	COG4251	negative regulation of phosphorylation
JG479_RS04115	COG3706	GGDEF domain
JG479_RS04115	COG2203	Gaf domain
JG479_RS04125	COG2319	Wd-40 repeat
JG479_RS04125	COG4249	Peptidase C14 caspase catalytic subunit p20
JG479_RS04130	COG0668	transmembrane transport
JG479_RS04135	COG1346	cytolysis
JG479_RS04145	COG1250	3-hydroxyacyl-CoA dehydrogenase
JG479_RS04145	COG1024	Enoyl-CoA hydratase
JG479_RS04150	COG3099	Belongs to the UPF0263 family
JG479_RS04165	COG1047	Peptidyl-prolyl cis-trans
JG479_RS04170	COG0354	folic acid binding
JG479_RS04175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JG479_RS04180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JG479_RS04185	COG1595	DNA-templated transcription, initiation
JG479_RS04205	COG0481	GTPase activity
JG479_RS04215	COG0571	ribonuclease III activity
JG479_RS04225	COG1381	Involved in DNA repair and RecF pathway recombination
JG479_RS04230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JG479_RS04235	COG4999	Histidine kinase
JG479_RS04235	COG2205	protein histidine kinase activity
JG479_RS04235	COG3850	Histidine kinase
JG479_RS04235	COG3437	response regulator, receiver
JG479_RS04240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JG479_RS04245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JG479_RS04250	COG3956	TIGRFAM MazG family protein
JG479_RS04255	COG0504	CTP synthase activity
JG479_RS04260	COG0148	phosphopyruvate hydratase activity
JG479_RS04265	COG3066	DNA modification
JG479_RS04270	COG1051	belongs to the nudix hydrolase family
JG479_RS04275	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
JG479_RS04280	COG0730	response to heat
JG479_RS04285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JG479_RS04290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JG479_RS04295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JG479_RS04345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JG479_RS04345	COG0678	peroxiredoxin activity
JG479_RS04370	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JG479_RS04375	COG2197	response regulator
JG479_RS04380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS04385	COG2274	protein secretion by the type I secretion system
JG479_RS04390	COG1538	Outer membrane efflux protein
JG479_RS04415	COG0835	chemotaxis
JG479_RS04415	COG0784	Response regulator, receiver
JG479_RS04420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG479_RS04425	COG1815	bacterial-type flagellum-dependent cell motility
JG479_RS04445	COG4787	bacterial-type flagellum-dependent cell motility
JG479_RS04450	COG4786	Flagellar basal body rod
JG479_RS04455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JG479_RS04460	COG1706	bacterial-type flagellum-dependent cell motility
JG479_RS04465	COG1705	Flagellar rod assembly protein muramidase FlgJ
JG479_RS04465	COG3951	Flagellar rod assembly protein muramidase FlgJ
JG479_RS04480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JG479_RS04485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JG479_RS04490	COG1334	flagellar protein FlaG
JG479_RS04495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JG479_RS04515	COG0519	Catalyzes the synthesis of GMP from XMP
JG479_RS04530	COG1677	Flagellar hook-basal body complex protein FliE
JG479_RS04540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JG479_RS04580	COG3190	flagellar
JG479_RS04590	COG1987	bacterial-type flagellum assembly
JG479_RS04605	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JG479_RS04630	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JG479_RS04635	COG0643	Histidine kinase
JG479_RS04635	COG2198	Histidine kinase
JG479_RS04635	COG0784	Response regulator, receiver
JG479_RS04640	COG2201	protein-glutamate methylesterase activity
JG479_RS04645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JG479_RS04650	COG1360	Flagellar Motor Protein
JG479_RS04655	COG1192	Involved in chromosome partitioning
JG479_RS04665	COG0835	chemotaxis
JG479_RS04685	COG4133	protoheme IX ABC transporter activity
JG479_RS04690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG479_RS04695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG479_RS04700	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JG479_RS04705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JG479_RS04710	COG1138	Cytochrome C-type biogenesis protein
JG479_RS04730	COG2853	Lipoprotein
JG479_RS04735	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JG479_RS04740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JG479_RS04745	COG3141	response to X-ray
JG479_RS04750	COG1555	photosystem II stabilization
JG479_RS04760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JG479_RS04765	COG2186	Transcriptional regulator
JG479_RS04770	COG0450	alkyl hydroperoxide reductase
JG479_RS04780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JG479_RS04785	COG2867	negative regulation of translational initiation
JG479_RS04790	COG2914	Belongs to the UPF0125 (RnfH) family
JG479_RS04795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JG479_RS04800	COG2827	Endonuclease containing a URI domain
JG479_RS04810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JG479_RS04815	COG0583	DNA-binding transcription factor activity
JG479_RS04820	COG3706	GGDEF domain
JG479_RS04835	COG0745	RESPONSE REGULATOR receiver
JG479_RS04840	COG2205	protein histidine kinase activity
JG479_RS04855	COG4326	sporulation control protein
JG479_RS04860	COG2153	protein acetylation
JG479_RS04865	COG0733	neurotransmitter:sodium symporter activity
JG479_RS04870	COG2205	protein histidine kinase activity
JG479_RS04875	COG0745	RESPONSE REGULATOR receiver
JG479_RS04895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JG479_RS04905	COG1534	Rna-binding protein
JG479_RS04910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JG479_RS04915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JG479_RS04920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JG479_RS04925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JG479_RS04930	COG0149	triose-phosphate isomerase activity
JG479_RS04935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JG479_RS04960	COG2197	response regulator
JG479_RS04970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JG479_RS04985	COG0101	tRNA pseudouridine synthase activity
JG479_RS04990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JG479_RS04995	COG0285	dihydrofolate synthase activity
JG479_RS05005	COG1286	toxin biosynthetic process
JG479_RS05010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JG479_RS05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JG479_RS05040	COG0215	cysteine-tRNA ligase activity
JG479_RS05045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JG479_RS05075	COG0544	peptidyl-prolyl cis-trans isomerase activity
JG479_RS05080	COG0740	serine-type endopeptidase activity
JG479_RS05085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JG479_RS05090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JG479_RS05100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG479_RS05110	COG4172	Belongs to the ABC transporter superfamily
JG479_RS05130	COG0747	negative chemotaxis
JG479_RS05135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JG479_RS05140	COG1842	Phage shock protein A
JG479_RS05150	COG1983	PspC domain protein
JG479_RS05155	COG3106	COG3106 Predicted ATPase
JG479_RS05160	COG3768	UPF0283 membrane protein
JG479_RS05165	COG0626	cystathionine gamma-synthase activity
JG479_RS05175	COG2154	pterin-4-alpha-carbinolamine dehydratase
JG479_RS05180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG479_RS05190	COG2171	N-acyltransferase activity
JG479_RS05195	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JG479_RS05200	COG0024	Methionine aminopeptidase
JG479_RS05205	COG0052	Belongs to the universal ribosomal protein uS2 family
JG479_RS05210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JG479_RS05215	COG0528	UMP kinase activity
JG479_RS05225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JG479_RS05230	COG0575	Belongs to the CDS family
JG479_RS05235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JG479_RS05240	COG0750	zinc metalloprotease
JG479_RS05255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JG479_RS05260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JG479_RS05265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JG479_RS05270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JG479_RS05275	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JG479_RS05280	COG4988	ABC transporter
JG479_RS05285	COG4890	Cyd operon protein YbgT
JG479_RS05290	COG1294	oxidase, subunit
JG479_RS05300	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JG479_RS05305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JG479_RS05310	COG0587	DNA-directed DNA polymerase activity
JG479_RS05315	COG0825	malonyl-CoA metabolic process
JG479_RS05355	COG0427	acetyl-CoA hydrolase
JG479_RS05370	COG0668	transmembrane transport
JG479_RS05380	COG2391	methyltransferase activity
JG479_RS05390	COG0477	Major facilitator Superfamily
JG479_RS05440	COG0123	including yeast histone deacetylase and acetoin utilization protein
JG479_RS05450	COG0730	response to heat
JG479_RS05455	COG1199	ATP-dependent helicase activity
JG479_RS05460	COG0417	DNA replication proofreading
JG479_RS05495	COG1061	Type III restriction enzyme res subunit
JG479_RS05505	COG0729	surface antigen
JG479_RS05520	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JG479_RS05520	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JG479_RS05530	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JG479_RS05560	COG3098	single-species biofilm formation
JG479_RS05565	COG0564	pseudouridine synthase activity
JG479_RS05710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JG479_RS05915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JG479_RS05920	COG0072	phenylalanine-tRNA ligase activity
JG479_RS05925	COG0776	regulation of translation
JG479_RS05940	COG2866	Carboxypeptidase
JG479_RS05945	COG1115	amino acid carrier protein
JG479_RS05955	COG3139	Protein of unknown function (DUF1315)
JG479_RS05975	COG3604	Transcriptional regulator
JG479_RS06000	COG0210	DNA helicase
JG479_RS06040	COG2755	lipolytic protein G-D-S-L family
JG479_RS06045	COG4181	ATPase activity
JG479_RS06050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JG479_RS06055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JG479_RS06060	COG0632	four-way junction helicase activity
JG479_RS06065	COG2255	four-way junction helicase activity
JG479_RS06070	COG0811	peptide transport
JG479_RS06085	COG0823	Involved in the tonB-independent uptake of proteins
JG479_RS06090	COG2885	chlorophyll binding
JG479_RS06095	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JG479_RS06140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JG479_RS06150	COG2205	protein histidine kinase activity
JG479_RS06150	COG0784	Response regulator, receiver
JG479_RS06165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JG479_RS06185	COG1902	pentaerythritol trinitrate reductase activity
JG479_RS06205	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JG479_RS06210	COG1074	ATP-dependent DNA helicase activity
JG479_RS06215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JG479_RS06235	COG0037	tRNA processing
JG479_RS06240	COG0589	response to stress
JG479_RS06245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JG479_RS06260	COG2217	Heavy metal translocating P-type atpase
JG479_RS06270	COG2010	Cytochrome c
JG479_RS06285	COG3278	Belongs to the heme-copper respiratory oxidase family
JG479_RS06295	COG4206	TonB-dependent receptor
JG479_RS06315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JG479_RS06320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JG479_RS06325	COG2957	Belongs to the agmatine deiminase family
JG479_RS06345	COG0583	DNA-binding transcription factor activity
JG479_RS06370	COG0848	biopolymer transport protein
JG479_RS06385	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JG479_RS06395	COG3083	sulfuric ester hydrolase activity
JG479_RS06400	COG3082	Protein of unknown function (DUF1414)
JG479_RS06405	COG3081	Nucleoid-associated protein
JG479_RS06410	COG1530	ribonuclease E activity
JG479_RS06430	COG0424	maF-like protein
JG479_RS06435	COG1399	metal-binding, possibly nucleic acid-binding protein
JG479_RS06440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JG479_RS06445	COG0416	fatty acid biosynthetic process
JG479_RS06450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JG479_RS06460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JG479_RS06465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JG479_RS06470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JG479_RS06475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JG479_RS06480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JG479_RS06485	COG0470	DNA polymerase III
JG479_RS06495	COG0084	hydrolase, TatD family'
JG479_RS06515	COG2199	diguanylate cyclase activity
JG479_RS06515	COG2200	EAL domain
JG479_RS06515	COG2203	Gaf domain
JG479_RS06525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JG479_RS06550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JG479_RS06560	COG0438	transferase activity, transferring glycosyl groups
JG479_RS06570	COG1045	serine acetyltransferase
JG479_RS06585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JG479_RS06605	COG1596	polysaccharide export
JG479_RS06630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JG479_RS06630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JG479_RS06640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JG479_RS06645	COG0372	Belongs to the citrate synthase family
JG479_RS06650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JG479_RS06655	COG2828	Protein conserved in bacteria
JG479_RS06680	COG2917	probably involved in intracellular septation
JG479_RS06690	COG0693	protein deglycase activity
JG479_RS06705	COG0135	phosphoribosylanthranilate isomerase activity
JG479_RS06705	COG0134	indole-3-glycerol-phosphate synthase activity
JG479_RS06710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JG479_RS06715	COG0512	Glutamine amidotransferase of anthranilate synthase
JG479_RS06720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JG479_RS06725	COG0613	PHP domain protein
JG479_RS06730	COG0009	L-threonylcarbamoyladenylate synthase
JG479_RS06740	COG3038	cytochrome b561
JG479_RS06795	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JG479_RS06815	COG0800	Aldolase
JG479_RS06820	COG2267	carboxylic ester hydrolase activity
JG479_RS06825	COG5001	Diguanylate cyclase
JG479_RS06830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG479_RS06830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JG479_RS06835	COG0489	protein tyrosine kinase activity
JG479_RS06840	COG0717	Belongs to the dCTP deaminase family
JG479_RS06860	COG0436	Aminotransferase
JG479_RS06865	COG3134	Outer membrane lipoprotein
JG479_RS06870	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
JG479_RS06890	COG3220	belongs to the UPF0276 family
JG479_RS06905	COG1876	peptidase activity
JG479_RS06910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JG479_RS06915	COG1393	Belongs to the ArsC family
JG479_RS06930	COG0857	belongs to the CobB CobQ family
JG479_RS06930	COG0280	phosphate acetyltransferase
JG479_RS06935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JG479_RS06940	COG3092	negative regulation of chromosome organization
JG479_RS06945	COG2226	methyltransferase
JG479_RS06970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JG479_RS06975	COG1187	pseudouridine synthase activity
JG479_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
JG479_RS06985	COG2267	carboxylic ester hydrolase activity
JG479_RS06990	COG0616	signal peptide processing
JG479_RS06995	COG1301	dicarboxylic acid transport
JG479_RS07015	COG0366	Alpha amylase catalytic
JG479_RS07030	COG0366	Alpha amylase catalytic
JG479_RS07060	COG0837	glucose binding
JG479_RS07065	COG1609	Transcriptional regulator
JG479_RS07075	COG0800	Aldolase
JG479_RS07095	COG0217	transcriptional regulatory protein
JG479_RS07100	COG3590	peptidase
JG479_RS07105	COG5265	(ABC) transporter
JG479_RS07120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG479_RS07125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG479_RS07150	COG2824	Alkylphosphonate utilization operon protein PhnA
JG479_RS07155	COG0189	ligase activity
JG479_RS07165	COG1285	pathogenesis
JG479_RS07195	COG1285	pathogenesis
JG479_RS07215	COG0583	DNA-binding transcription factor activity
JG479_RS07220	COG4591	ABC-type transport system involved in lipoprotein release permease component
JG479_RS07225	COG1136	(ABC) transporter
JG479_RS07230	COG4591	ABC-type transport system involved in lipoprotein release permease component
JG479_RS07235	COG4807	Protein conserved in bacteria
JG479_RS07240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JG479_RS07245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JG479_RS07250	COG0318	PFAM AMP-dependent synthetase and ligase
JG479_RS07265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JG479_RS07270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JG479_RS07275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JG479_RS07285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG479_RS07290	COG1522	sequence-specific DNA binding
JG479_RS07295	COG0659	secondary active sulfate transmembrane transporter activity
JG479_RS07300	COG2972	Histidine kinase
JG479_RS07305	COG3279	Response regulator of the LytR AlgR family
JG479_RS07310	COG0469	pyruvate kinase activity
JG479_RS07320	COG0252	asparaginase activity
JG479_RS07325	COG0616	signal peptide processing
JG479_RS07330	COG0446	pyridine nucleotide-disulphide oxidoreductase
JG479_RS07330	COG1902	pentaerythritol trinitrate reductase activity
JG479_RS07340	COG0778	Nitroreductase
JG479_RS07360	COG0545	Peptidyl-prolyl cis-trans isomerase
JG479_RS07385	COG0596	Alpha beta hydrolase
JG479_RS07405	COG3738	Protein conserved in bacteria
JG479_RS07420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JG479_RS07430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JG479_RS07440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JG479_RS07445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JG479_RS07450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JG479_RS07455	COG0539	negative regulation of cytoplasmic translation
JG479_RS07460	COG0776	regulation of translation
JG479_RS07470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JG479_RS07475	COG0284	orotidine-5'-phosphate decarboxylase activity
JG479_RS07490	COG0513	Belongs to the DEAD box helicase family
JG479_RS07495	COG1054	Belongs to the UPF0176 family
JG479_RS07500	COG0517	IMP dehydrogenase activity
JG479_RS07500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JG479_RS07505	COG2176	DNA-directed DNA polymerase activity
JG479_RS07510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG479_RS07515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JG479_RS07520	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JG479_RS07530	COG0367	asparagine synthase
JG479_RS07535	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JG479_RS07545	COG1984	allophanate hydrolase subunit 2
JG479_RS07550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JG479_RS07555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG479_RS07555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG479_RS07565	COG0583	DNA-binding transcription factor activity
JG479_RS07575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JG479_RS07585	COG4770	biotin carboxylase activity
JG479_RS07595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JG479_RS07600	COG1960	acyl-CoA dehydrogenase activity
JG479_RS07610	COG0183	Belongs to the thiolase family
JG479_RS07625	COG1024	Enoyl-CoA hydratase
JG479_RS07630	COG1024	Enoyl-CoA hydratase
JG479_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
JG479_RS07655	COG2329	Antibiotic biosynthesis monooxygenase
JG479_RS07770	COG4628	conserved protein (DUF2132)
JG479_RS07775	COG0604	alcohol dehydrogenase
JG479_RS07780	COG1309	transcriptional regulator
JG479_RS07785	COG3130	regulation of translation
JG479_RS07790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JG479_RS07805	COG1607	acyl-coa hydrolase
JG479_RS07810	COG2056	Na+-H+ antiporter family
JG479_RS07825	COG0714	Associated with various cellular activities
JG479_RS07945	COG0281	malic enzyme
JG479_RS07950	COG0405	Gamma-glutamyltransferase
JG479_RS07970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JG479_RS07975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JG479_RS07980	COG0488	(ABC) transporter
JG479_RS08020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG479_RS08040	COG5001	Diguanylate cyclase
JG479_RS08040	COG3300	MHYT domain
JG479_RS08075	COG0701	Predicted permease
JG479_RS08085	COG2860	membrane
JG479_RS08110	COG0501	Belongs to the peptidase M48B family
JG479_RS08120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JG479_RS08125	COG2226	methyltransferase
JG479_RS08135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JG479_RS08140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JG479_RS08155	COG1178	ABC-type Fe3 transport system permease component
JG479_RS08160	COG3842	ATPase activity
JG479_RS08165	COG2205	protein histidine kinase activity
JG479_RS08165	COG2202	Pas domain
JG479_RS08170	COG0784	Response regulator, receiver
JG479_RS08175	COG3437	response regulator, receiver
JG479_RS08185	COG0017	Asparaginyl-tRNA synthetase
JG479_RS08215	COG1720	tRNA m6t6A37 methyltransferase activity
JG479_RS08220	COG0442	prolyl-tRNA aminoacylation
JG479_RS08235	COG1668	transmembrane transport
JG479_RS08240	COG4555	ABC transporter
JG479_RS08260	COG3152	Membrane
JG479_RS08265	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG479_RS08270	COG0022	dehydrogenase e1 component
JG479_RS08280	COG2988	succinylglutamate desuccinylase activity
JG479_RS08285	COG0033	Phosphoglucomutase
JG479_RS08290	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JG479_RS08295	COG0596	Alpha beta hydrolase
JG479_RS08315	COG0735	belongs to the Fur family
JG479_RS08320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JG479_RS08335	COG0045	succinate-CoA ligase (ADP-forming) activity
JG479_RS08340	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG479_RS08345	COG0567	Dehydrogenase, E1 component
JG479_RS08355	COG1053	succinate dehydrogenase
JG479_RS08360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JG479_RS08375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JG479_RS08380	COG2166	iron-sulfur cluster assembly
JG479_RS08385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JG479_RS08390	COG0564	pseudouridine synthase activity
JG479_RS08395	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JG479_RS08400	COG2835	tetraacyldisaccharide 4'-kinase activity
JG479_RS08405	COG1663	tetraacyldisaccharide 4'-kinase activity
JG479_RS08410	COG1132	(ABC) transporter
JG479_RS08415	COG2333	competence protein COMEC
JG479_RS08415	COG0658	competence protein
JG479_RS08430	COG0488	(ABC) transporter
JG479_RS08440	COG0116	Belongs to the methyltransferase superfamily
JG479_RS08440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JG479_RS08450	COG0167	dihydroorotate dehydrogenase activity
JG479_RS08455	COG2902	Dehydrogenase
JG479_RS08465	COG4447	cellulose binding
JG479_RS08485	COG0308	aminopeptidase N
JG479_RS08490	COG1757	Na H antiporter
JG479_RS08500	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JG479_RS08510	COG1956	GAF domain-containing protein
JG479_RS08530	COG3279	Response regulator of the LytR AlgR family
JG479_RS08545	COG0670	Belongs to the BI1 family
JG479_RS08555	COG2923	Belongs to the DsrF TusC family
JG479_RS08565	COG2920	part of a sulfur-relay system
JG479_RS08570	COG1187	pseudouridine synthase activity
JG479_RS08580	COG0482	sulfurtransferase activity
JG479_RS08585	COG2915	High frequency lysogenization protein hflD homolog
JG479_RS08590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JG479_RS08595	COG2850	peptidyl-arginine hydroxylation
JG479_RS08610	COG2234	aminopeptidase activity
JG479_RS08635	COG1132	(ABC) transporter
JG479_RS08645	COG3706	GGDEF domain
JG479_RS08655	COG0826	peptidase U32
JG479_RS08665	COG3977	Valine--pyruvate aminotransferase
JG479_RS08670	COG1914	H( )-stimulated, divalent metal cation uptake system
JG479_RS08680	COG2133	pyrroloquinoline quinone binding
JG479_RS08695	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JG479_RS08700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JG479_RS08705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JG479_RS08710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JG479_RS08715	COG0531	amino acid
JG479_RS08715	COG1674	ftsk spoiiie
JG479_RS08725	COG0686	Belongs to the AlaDH PNT family
JG479_RS08730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JG479_RS08735	COG0492	ferredoxin-NADP+ reductase activity
JG479_RS08740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JG479_RS08745	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JG479_RS08750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JG479_RS08755	COG0542	response to heat
JG479_RS08760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JG479_RS08765	COG1278	Cold shock
JG479_RS08775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JG479_RS08780	COG1228	amidohydrolase
JG479_RS08795	COG3001	Fructosamine kinase
JG479_RS08805	COG0307	riboflavin synthase, alpha
JG479_RS08835	COG3291	Pkd domain containing protein
JG479_RS08840	COG1472	Belongs to the glycosyl hydrolase 3 family
JG479_RS08860	COG1472	Belongs to the glycosyl hydrolase 3 family
JG479_RS08865	COG0477	Major facilitator Superfamily
JG479_RS08870	COG0745	RESPONSE REGULATOR receiver
JG479_RS08875	COG2205	protein histidine kinase activity
JG479_RS08880	COG0569	domain protein
JG479_RS08885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JG479_RS08890	COG0477	Major facilitator Superfamily
JG479_RS08895	COG1609	Transcriptional regulator
JG479_RS08900	COG3507	Belongs to the glycosyl hydrolase 43 family
JG479_RS08910	COG1070	Carbohydrate kinase
JG479_RS08915	COG2115	Belongs to the xylose isomerase family
JG479_RS08920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JG479_RS08925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JG479_RS08950	COG0583	DNA-binding transcription factor activity
JG479_RS08965	COG3693	PFAM glycoside hydrolase, family 10
JG479_RS08990	COG1621	beta-fructofuranosidase activity
JG479_RS08995	COG2814	Major facilitator Superfamily
JG479_RS08995	COG0477	Major facilitator Superfamily
JG479_RS09025	COG4771	TonB-dependent receptor
JG479_RS09035	COG2211	Major facilitator Superfamily
JG479_RS09060	COG4968	Prepilin-type N-terminal cleavage methylation domain
JG479_RS09070	COG0659	secondary active sulfate transmembrane transporter activity
JG479_RS09075	COG0589	response to stress
JG479_RS09080	COG0583	DNA-binding transcription factor activity
JG479_RS09100	COG2146	nitrite reductase [NAD(P)H] activity
JG479_RS09100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG479_RS09105	COG2146	nitrite reductase [NAD(P)H] activity
JG479_RS09110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JG479_RS09110	COG1648	precorrin-2 dehydrogenase activity
JG479_RS09125	COG5001	Diguanylate cyclase
JG479_RS09125	COG3300	MHYT domain
JG479_RS09135	COG5002	protein histidine kinase activity
JG479_RS09145	COG0583	DNA-binding transcription factor activity
JG479_RS09150	COG2258	MOSC domain
JG479_RS09155	COG0314	molybdopterin synthase activity
JG479_RS09160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JG479_RS09165	COG0315	cyclic pyranopterin monophosphate synthase activity
JG479_RS09170	COG0521	Mo-molybdopterin cofactor biosynthetic process
JG479_RS09175	COG0746	molybdenum cofactor guanylyltransferase activity
JG479_RS09185	COG0243	molybdopterin cofactor binding
JG479_RS09190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG479_RS09200	COG0515	serine threonine protein kinase
JG479_RS09200	COG2815	serine threonine protein kinase
JG479_RS09205	COG2223	nitrite transmembrane transporter activity
JG479_RS09210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JG479_RS09240	COG0733	neurotransmitter:sodium symporter activity
JG479_RS09245	COG2350	Protein conserved in bacteria
JG479_RS09275	COG0628	permease
JG479_RS09280	COG1090	epimerase
JG479_RS09285	COG2199	diguanylate cyclase activity
JG479_RS09290	COG1472	Belongs to the glycosyl hydrolase 3 family
JG479_RS09300	COG2723	6-phospho-beta-galactosidase activity
JG479_RS09305	COG2211	Major facilitator Superfamily
JG479_RS09310	COG1609	Transcriptional regulator
JG479_RS09325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JG479_RS09330	COG1505	serine-type exopeptidase activity
JG479_RS09355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JG479_RS09355	COG0543	2 iron, 2 sulfur cluster binding
JG479_RS09360	COG2133	pyrroloquinoline quinone binding
JG479_RS09385	COG3647	Membrane
JG479_RS09390	COG0300	oxidoreductase activity
JG479_RS09430	COG1472	Belongs to the glycosyl hydrolase 3 family
JG479_RS09440	COG2211	Major facilitator Superfamily
JG479_RS09485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG479_RS09490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JG479_RS09495	COG1012	belongs to the aldehyde dehydrogenase family
JG479_RS09505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JG479_RS09540	COG0596	Alpha beta hydrolase
JG479_RS09590	COG2925	Exonuclease
JG479_RS09595	COG2084	Dehydrogenase
JG479_RS09600	COG0386	Belongs to the glutathione peroxidase family
JG479_RS09605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JG479_RS09610	COG0733	neurotransmitter:sodium symporter activity
JG479_RS09620	COG0527	aspartate kinase activity
JG479_RS09700	COG0583	DNA-binding transcription factor activity
JG479_RS09715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG479_RS09730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JG479_RS09735	COG0505	Belongs to the CarA family
JG479_RS09740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JG479_RS09755	COG2267	carboxylic ester hydrolase activity
JG479_RS09765	COG2814	Major facilitator Superfamily
JG479_RS09770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JG479_RS09775	COG1420	regulation of RNA biosynthetic process
JG479_RS09780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JG479_RS09790	COG0497	DNA recombination
JG479_RS09810	COG0493	'glutamate synthase
JG479_RS09815	COG0069	glutamate synthase activity
JG479_RS09815	COG0070	glutamate synthase
JG479_RS09815	COG0067	glutamate synthase
JG479_RS09825	COG1136	(ABC) transporter
JG479_RS09830	COG1136	(ABC) transporter
JG479_RS09830	COG0577	efflux transmembrane transporter activity
JG479_RS09835	COG1136	(ABC) transporter
JG479_RS09835	COG0577	efflux transmembrane transporter activity
JG479_RS09840	COG2204	response regulator
JG479_RS09845	COG5000	phosphorelay sensor kinase activity
JG479_RS09850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JG479_RS09855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JG479_RS09860	COG2766	serine protein kinase
JG479_RS09865	COG2718	Belongs to the UPF0229 family
JG479_RS09870	COG2719	SpoVR family
JG479_RS09875	COG3706	GGDEF domain
JG479_RS09880	COG2201	protein-glutamate methylesterase activity
JG479_RS09885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JG479_RS09890	COG0563	adenylate kinase activity
JG479_RS09895	COG0326	Molecular chaperone. Has ATPase activity
JG479_RS09900	COG0564	pseudouridine synthase activity
JG479_RS09910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JG479_RS09915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JG479_RS09925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JG479_RS09930	COG3219	Protein conserved in bacteria
JG479_RS09935	COG3220	belongs to the UPF0276 family
JG479_RS09945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JG479_RS09970	COG0848	biopolymer transport protein
JG479_RS09975	COG0811	peptide transport
JG479_RS09980	COG0811	peptide transport
JG479_RS09990	COG1278	Cold shock
JG479_RS10000	COG3300	MHYT domain
JG479_RS10000	COG5001	Diguanylate cyclase
JG479_RS10005	COG0583	DNA-binding transcription factor activity
JG479_RS10010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JG479_RS10015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JG479_RS10030	COG3228	Belongs to the MtfA family
JG479_RS10040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JG479_RS10050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JG479_RS10055	COG0494	nUDIX hydrolase
JG479_RS10060	COG1760	l-serine dehydratase
JG479_RS10065	COG0583	DNA-binding transcription factor activity
JG479_RS10075	COG2252	PERMEase
JG479_RS10090	COG3012	SEC-C Motif Domain Protein
JG479_RS10095	COG2203	Gaf domain
JG479_RS10095	COG3706	GGDEF domain
JG479_RS10095	COG4251	negative regulation of phosphorylation
JG479_RS10095	COG5001	Diguanylate cyclase
JG479_RS10125	COG2205	protein histidine kinase activity
JG479_RS10125	COG2198	Histidine kinase
JG479_RS10125	COG0784	Response regulator, receiver
JG479_RS10130	COG3437	response regulator, receiver
JG479_RS10140	COG1418	mRNA catabolic process
JG479_RS10145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JG479_RS10160	COG1643	Atp-dependent helicase
JG479_RS10165	COG1446	asparaginase
JG479_RS10175	COG0363	glucosamine-6-phosphate deaminase activity
JG479_RS10180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JG479_RS10185	COG0166	Belongs to the GPI family
JG479_RS10190	COG1104	cysteine desulfurase activity
JG479_RS10210	COG4783	chaperone-mediated protein folding
JG479_RS10215	COG1393	Belongs to the ArsC family
JG479_RS10235	COG2854	intermembrane phospholipid transfer
JG479_RS10250	COG3314	Sporulation integral membrane protein YlbJ
JG479_RS10260	COG2716	regulation of RNA biosynthetic process
JG479_RS10265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JG479_RS10280	COG2226	methyltransferase
JG479_RS10285	COG0602	queuosine metabolic process
JG479_RS10290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JG479_RS10315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JG479_RS10320	COG0556	nucleotide-excision repair
JG479_RS10325	COG0534	Mate efflux family protein
JG479_RS10350	COG2200	EAL domain
JG479_RS10350	COG2199	diguanylate cyclase activity
JG479_RS10360	COG4657	Part of a membrane complex involved in electron transport
JG479_RS10375	COG4658	electron transport chain
JG479_RS10380	COG4659	FMN binding
JG479_RS10385	COG4660	Part of a membrane complex involved in electron transport
JG479_RS10390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JG479_RS10405	COG1982	Orn Lys Arg decarboxylase major
JG479_RS10425	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JG479_RS10435	COG0800	Aldolase
JG479_RS10440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG479_RS10445	COG2271	Major facilitator Superfamily
JG479_RS10450	COG1917	Cupin 2, conserved barrel domain protein
JG479_RS10470	COG0346	lactoylglutathione lyase activity
JG479_RS10475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JG479_RS10480	COG0612	Peptidase, M16
JG479_RS10565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JG479_RS10580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JG479_RS10585	COG3115	cell septum assembly
JG479_RS10590	COG1196	nuclear chromosome segregation
JG479_RS10595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JG479_RS10605	COG1566	PFAM secretion protein HlyD family protein
JG479_RS10615	COG4269	membrane
JG479_RS10635	COG1166	arginine decarboxylase activity
JG479_RS10645	COG1742	UPF0060 membrane protein
JG479_RS10665	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JG479_RS10680	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JG479_RS10685	COG2363	Small membrane protein
JG479_RS10695	COG0583	DNA-binding transcription factor activity
JG479_RS10700	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JG479_RS10705	COG5505	Protein of unknown function (DUF819)
JG479_RS10720	COG3437	response regulator, receiver
JG479_RS10720	COG0784	Response regulator, receiver
JG479_RS10725	COG2890	protein-(glutamine-N5) methyltransferase activity
JG479_RS10730	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JG479_RS10735	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JG479_RS10740	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JG479_RS10745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JG479_RS10755	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JG479_RS10760	COG0193	aminoacyl-tRNA hydrolase activity
JG479_RS10765	COG0012	GTP binding
JG479_RS10820	COG5001	Diguanylate cyclase
JG479_RS10820	COG3300	MHYT domain
JG479_RS10825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JG479_RS10830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JG479_RS10835	COG1702	phosphate starvation-inducible protein PhoH
JG479_RS10840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JG479_RS10845	COG4535	Mg2 and Co2 transporter CorC
JG479_RS10850	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JG479_RS10875	COG1902	pentaerythritol trinitrate reductase activity
JG479_RS10900	COG0545	Peptidyl-prolyl cis-trans isomerase
JG479_RS10905	COG1067	ATP-dependent peptidase activity
JG479_RS10910	COG2888	peptidyl-tyrosine sulfation
JG479_RS10915	COG0495	leucyl-tRNA aminoacylation
JG479_RS10930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JG479_RS10935	COG0799	negative regulation of ribosome biogenesis
JG479_RS10940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JG479_RS10945	COG0768	penicillin binding
JG479_RS10950	COG0772	Belongs to the SEDS family
JG479_RS10955	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JG479_RS10960	COG1686	Belongs to the peptidase S11 family
JG479_RS10965	COG2921	Belongs to the UPF0250 family
JG479_RS10970	COG0321	lipoyl(octanoyl) transferase activity
JG479_RS10975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JG479_RS10985	COG0724	RNA recognition motif
JG479_RS11045	COG1320	monovalent cation:proton antiporter activity
JG479_RS11050	COG2212	antiporter activity
JG479_RS11055	COG1863	multisubunit Na H antiporter MnhE subunit
JG479_RS11060	COG0651	ATP synthesis coupled electron transport
JG479_RS11065	COG1006	Multisubunit Na H antiporter MnhC subunit
JG479_RS11070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JG479_RS11070	COG2111	Na H antiporter
JG479_RS11085	COG1185	polyribonucleotide nucleotidyltransferase activity
JG479_RS11090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JG479_RS11095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JG479_RS11100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JG479_RS11105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JG479_RS11110	COG0195	Participates in both transcription termination and antitermination
JG479_RS11115	COG0779	Required for maturation of 30S ribosomal subunits
JG479_RS11130	COG3046	protein related to deoxyribodipyrimidine photolyase
JG479_RS11140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JG479_RS11155	COG4251	negative regulation of phosphorylation
JG479_RS11155	COG5001	Diguanylate cyclase
JG479_RS11155	COG2203	Gaf domain
JG479_RS11155	COG3706	GGDEF domain
JG479_RS11165	COG4999	Histidine kinase
JG479_RS11165	COG3850	Histidine kinase
JG479_RS11165	COG3437	response regulator, receiver
JG479_RS11165	COG2205	protein histidine kinase activity
JG479_RS11170	COG1335	isochorismatase
JG479_RS11195	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JG479_RS11210	COG3101	peptidyl-lysine hydroxylation
JG479_RS11230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JG479_RS11235	COG2890	protein-(glutamine-N5) methyltransferase activity
JG479_RS11240	COG2840	Smr protein MutS2
JG479_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
JG479_RS11255	COG0251	oxidation-reduction process
JG479_RS11260	COG2062	phosphohistidine phosphatase, SixA
JG479_RS11265	COG1025	Belongs to the peptidase M16 family
JG479_RS11270	COG3300	MHYT domain
JG479_RS11270	COG5001	Diguanylate cyclase
JG479_RS11275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JG479_RS11280	COG2315	Protein conserved in bacteria
JG479_RS11290	COG1250	3-hydroxyacyl-CoA dehydrogenase
JG479_RS11290	COG1024	Enoyl-CoA hydratase
JG479_RS11295	COG0183	Belongs to the thiolase family
JG479_RS11300	COG0714	Associated with various cellular activities
JG479_RS11315	COG2304	oxidoreductase activity
JG479_RS11330	COG1595	DNA-templated transcription, initiation
JG479_RS11360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JG479_RS11365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JG479_RS11365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JG479_RS11375	COG0702	epimerase
JG479_RS11425	COG0814	amino acid
JG479_RS11430	COG1448	Aminotransferase
JG479_RS11450	COG0023	Translation Initiation Factor
JG479_RS11460	COG0077	Prephenate dehydratase
JG479_RS11460	COG1605	Chorismate mutase
JG479_RS11465	COG0287	Prephenate dehydrogenase
JG479_RS11465	COG1605	Chorismate mutase
JG479_RS11470	COG0335	large ribosomal subunit rRNA binding
JG479_RS11475	COG0336	Belongs to the RNA methyltransferase TrmD family
JG479_RS11480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JG479_RS11485	COG0228	four-way junction DNA binding
JG479_RS11490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JG479_RS11495	COG4137	Cytochrome C assembly protein
JG479_RS11500	COG4536	flavin adenine dinucleotide binding
JG479_RS11510	COG2918	glutathione biosynthetic process
JG479_RS11515	COG0840	transmembrane signaling receptor activity
JG479_RS11520	COG0542	response to heat
JG479_RS11530	COG0564	pseudouridine synthase activity
JG479_RS11535	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JG479_RS11585	COG3275	phosphorelay sensor kinase activity
JG479_RS11590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JG479_RS11595	COG1047	Peptidyl-prolyl cis-trans
JG479_RS11600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JG479_RS11605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JG479_RS11610	COG0196	riboflavin kinase activity
JG479_RS11615	COG0728	peptidoglycan biosynthetic process
JG479_RS11620	COG0268	Binds directly to 16S ribosomal RNA
JG479_RS11625	COG2201	protein-glutamate methylesterase activity
JG479_RS11645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JG479_RS11655	COG3047	cAMP biosynthetic process
JG479_RS11675	COG2194	sulfuric ester hydrolase activity
JG479_RS11695	COG1215	transferase activity, transferring glycosyl groups
JG479_RS11705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JG479_RS11710	COG0457	Tetratricopeptide repeat
JG479_RS11730	COG0179	Fumarylacetoacetate (FAA) hydrolase
JG479_RS11735	COG0739	heme binding
JG479_RS11760	COG1803	Methylglyoxal synthase
JG479_RS11765	COG0443	Heat shock 70 kDa protein
JG479_RS11775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JG479_RS11785	COG4771	TonB-dependent receptor
JG479_RS11790	COG3264	Mechanosensitive ion channel
JG479_RS11790	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JG479_RS11800	COG0339	signal peptide processing
JG479_RS11820	COG0583	DNA-binding transcription factor activity
JG479_RS11835	COG0625	glutathione transferase activity
JG479_RS11865	COG0745	RESPONSE REGULATOR receiver
JG479_RS11870	COG2205	protein histidine kinase activity
JG479_RS11890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JG479_RS11895	COG0415	Belongs to the DNA photolyase family
JG479_RS11905	COG1764	response to oxidative stress
JG479_RS11940	COG2814	Major facilitator Superfamily
JG479_RS11945	COG1064	alcohol dehydrogenase
JG479_RS11970	COG2203	Gaf domain
JG479_RS11970	COG2199	diguanylate cyclase activity
JG479_RS11985	COG1643	Atp-dependent helicase
JG479_RS11990	COG3237	CsbD-like
JG479_RS12020	COG1410	methionine synthase
JG479_RS12020	COG0646	methionine synthase
JG479_RS12025	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JG479_RS12030	COG0488	(ABC) transporter
JG479_RS12040	COG0123	including yeast histone deacetylase and acetoin utilization protein
JG479_RS12055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JG479_RS12070	COG0109	protoheme IX farnesyltransferase activity
JG479_RS12090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JG479_RS12100	COG2991	Protein conserved in bacteria
JG479_RS12105	COG1477	protein flavinylation
JG479_RS12110	COG2871	sodium ion transport
JG479_RS12115	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JG479_RS12120	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JG479_RS12125	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JG479_RS12130	COG1805	sodium ion transport
JG479_RS12135	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JG479_RS12140	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JG479_RS12145	COG0271	Belongs to the BolA IbaG family
JG479_RS12155	COG2813	Specifically methylates the guanine in position
JG479_RS12170	COG2211	Major facilitator Superfamily
JG479_RS12185	COG0316	Belongs to the HesB IscA family
JG479_RS12195	COG1981	membrane
JG479_RS12200	COG0540	Belongs to the ATCase OTCase family
JG479_RS12205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JG479_RS12210	COG0840	transmembrane signaling receptor activity
JG479_RS12215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JG479_RS12220	COG0004	ammonium transporteR
JG479_RS12230	COG3706	GGDEF domain
JG479_RS12240	COG0784	Response regulator, receiver
JG479_RS12240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG479_RS12240	COG2205	protein histidine kinase activity
JG479_RS12240	COG2198	Histidine kinase
JG479_RS12255	COG3025	triphosphatase activity
JG479_RS12270	COG2239	Acts as a magnesium transporter
JG479_RS12280	COG1846	Transcriptional regulator
JG479_RS12315	COG0438	transferase activity, transferring glycosyl groups
JG479_RS12330	COG2989	Protein conserved in bacteria
JG479_RS12345	COG0788	formyltetrahydrofolate deformylase activity
JG479_RS12355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JG479_RS12365	COG4773	Receptor
JG479_RS12380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JG479_RS12385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JG479_RS12400	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JG479_RS12405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JG479_RS12410	COG0585	pseudouridine synthase activity
JG479_RS12415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JG479_RS12420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JG479_RS12425	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JG479_RS12445	COG3283	Transcriptional regulator of aromatic amino acids metabolism
JG479_RS12480	COG0454	-acetyltransferase
JG479_RS12495	COG3123	guanosine phosphorylase activity
JG479_RS12500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JG479_RS12505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JG479_RS12515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JG479_RS12520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JG479_RS12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JG479_RS12530	COG0076	glutamate decarboxylase activity
JG479_RS12535	COG3287	FIST C domain
JG479_RS12535	COG2199	diguanylate cyclase activity
JG479_RS12535	COG2200	EAL domain
JG479_RS12540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JG479_RS12545	COG0842	Transport permease protein
JG479_RS12550	COG1131	(ABC) transporter
JG479_RS12555	COG0163	prenyltransferase activity
JG479_RS12560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JG479_RS12570	COG1968	undecaprenyl-diphosphatase activity
JG479_RS12575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JG479_RS12585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JG479_RS12590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JG479_RS12610	COG0583	DNA-binding transcription factor activity
JG479_RS12620	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JG479_RS12625	COG3161	chorismate lyase activity
JG479_RS12630	COG1580	Controls the rotational direction of flagella during chemotaxis
JG479_RS12635	COG0705	Rhomboid family
JG479_RS12640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG479_RS12645	COG1063	alcohol dehydrogenase
JG479_RS12655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JG479_RS12660	COG0859	PFAM glycosyl transferase family 9
JG479_RS12665	COG3642	lipopolysaccharide core region biosynthetic process
JG479_RS12685	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JG479_RS12685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JG479_RS12690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JG479_RS12695	COG1519	Transferase
JG479_RS12705	COG3784	Protein of unknown function (DUF1318)
JG479_RS12720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JG479_RS12720	COG0047	phosphoribosylformylglycinamidine synthase activity
JG479_RS12725	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JG479_RS12740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG479_RS12745	COG2066	Belongs to the glutaminase family
JG479_RS12770	COG3118	belongs to the thioredoxin family
JG479_RS12775	COG1473	amidohydrolase
JG479_RS12780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JG479_RS12795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JG479_RS12800	COG1722	exodeoxyribonuclease VII activity
JG479_RS12805	COG0142	geranyltranstransferase activity
JG479_RS12810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JG479_RS12815	COG3706	GGDEF domain
JG479_RS12820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JG479_RS12830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JG479_RS12835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JG479_RS12850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JG479_RS12850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JG479_RS12855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JG479_RS12860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JG479_RS12865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JG479_RS12880	COG0745	RESPONSE REGULATOR receiver
JG479_RS12885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG479_RS12885	COG4191	Histidine kinase
JG479_RS12890	COG2974	May be involved in recombination
JG479_RS12915	COG1489	DNA binding
JG479_RS12920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JG479_RS12935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JG479_RS12940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JG479_RS12945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JG479_RS12960	COG5002	protein histidine kinase activity
JG479_RS12965	COG0745	RESPONSE REGULATOR receiver
JG479_RS12975	COG0126	phosphoglycerate kinase activity
JG479_RS12980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JG479_RS12985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JG479_RS13000	COG0516	GMP reductase activity
JG479_RS13000	COG0517	IMP dehydrogenase activity
JG479_RS13005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JG479_RS13015	COG2205	protein histidine kinase activity
JG479_RS13015	COG0784	Response regulator, receiver
JG479_RS13030	COG3706	GGDEF domain
JG479_RS13035	COG0398	Pfam SNARE associated Golgi protein
JG479_RS13070	COG3250	beta-galactosidase activity
JG479_RS13075	COG2259	Doxx family
JG479_RS13080	COG1979	alcohol dehydrogenase
JG479_RS13085	COG2207	Transcriptional regulator
JG479_RS13125	COG1051	belongs to the nudix hydrolase family
JG479_RS13145	COG2205	protein histidine kinase activity
JG479_RS13150	COG0745	RESPONSE REGULATOR receiver
JG479_RS13155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG479_RS13160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS13175	COG1902	pentaerythritol trinitrate reductase activity
JG479_RS13190	COG0795	lipopolysaccharide-transporting ATPase activity
JG479_RS13195	COG0795	lipopolysaccharide-transporting ATPase activity
JG479_RS13200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JG479_RS13205	COG2927	DNA polymerase III (CHI subunit)
JG479_RS13210	COG0525	valine-tRNA ligase activity
JG479_RS13215	COG2067	long-chain fatty acid transport protein
JG479_RS13220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JG479_RS13270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JG479_RS13275	COG0305	Participates in initiation and elongation during chromosome replication
JG479_RS13290	COG1595	DNA-templated transcription, initiation
JG479_RS13295	COG0359	binds to the 23S rRNA
JG479_RS13300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JG479_RS13305	COG2965	DNA replication, synthesis of RNA primer
JG479_RS13310	COG0360	Binds together with S18 to 16S ribosomal RNA
JG479_RS13325	COG1506	peptidase
JG479_RS13330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JG479_RS13335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JG479_RS13340	COG0006	proline dipeptidase activity
JG479_RS13360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS13400	COG0784	Response regulator, receiver
JG479_RS13400	COG2205	protein histidine kinase activity
JG479_RS13400	COG5002	protein histidine kinase activity
JG479_RS13405	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JG479_RS13410	COG1194	a g-specific adenine glycosylase
JG479_RS13415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JG479_RS13420	COG2813	Specifically methylates the guanine in position
JG479_RS13425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG479_RS13425	COG4191	Histidine kinase
JG479_RS13430	COG0745	RESPONSE REGULATOR receiver
JG479_RS13435	COG5002	protein histidine kinase activity
JG479_RS13435	COG2198	Histidine kinase
JG479_RS13435	COG0784	Response regulator, receiver
JG479_RS13440	COG1469	GTP cyclohydrolase I activity
JG479_RS13450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JG479_RS13460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JG479_RS13475	COG4989	oxidoreductase activity
JG479_RS13490	COG3630	sodium ion export across plasma membrane
JG479_RS13510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JG479_RS13520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JG479_RS13535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JG479_RS13550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JG479_RS13590	COG3263	regulation of cellular component size
JG479_RS13595	COG1757	Na H antiporter
JG479_RS13600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JG479_RS13605	COG3876	Protein conserved in bacteria
JG479_RS13640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JG479_RS13665	COG0716	FMN binding
JG479_RS13685	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JG479_RS13690	COG0513	Belongs to the DEAD box helicase family
JG479_RS13700	COG0668	transmembrane transport
JG479_RS13705	COG3022	response to hydroperoxide
JG479_RS13720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JG479_RS13725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JG479_RS13730	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JG479_RS13735	COG1492	cobalamin metabolic process
JG479_RS13740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG479_RS13745	COG1120	ATPase activity
JG479_RS13755	COG0583	DNA-binding transcription factor activity
JG479_RS13760	COG3085	chromosome segregation
JG479_RS13770	COG2962	Rard protein
JG479_RS13775	COG2050	protein possibly involved in aromatic compounds catabolism
JG479_RS13780	COG0514	ATP-dependent DNA helicase (RecQ)
JG479_RS13805	COG0189	ligase activity
JG479_RS13810	COG0189	ligase activity
JG479_RS13810	COG4067	protein conserved in archaea
JG479_RS13825	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
JG479_RS13830	COG0204	Acyl-transferase
JG479_RS13850	COG3150	esterase
JG479_RS13860	COG3151	Protein conserved in bacteria
JG479_RS13865	COG0494	nUDIX hydrolase
JG479_RS13870	COG1538	Outer membrane efflux protein
JG479_RS13875	COG1560	Kdo2-lipid A biosynthetic process
JG479_RS13885	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JG479_RS13900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JG479_RS13905	COG0189	ligase activity
JG479_RS13910	COG1678	Uncharacterized ACR, COG1678
JG479_RS13915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JG479_RS13930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JG479_RS13935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JG479_RS13940	COG0762	integral membrane protein
JG479_RS13950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JG479_RS13955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JG479_RS13980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG479_RS13980	COG1042	CoA-binding domain protein
JG479_RS13980	COG0045	succinate-CoA ligase (ADP-forming) activity
JG479_RS13985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JG479_RS14010	COG3313	Fe-S protein
JG479_RS14020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JG479_RS14040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JG479_RS14045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JG479_RS14060	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JG479_RS14075	COG2897	thiosulfate sulfurtransferase activity
JG479_RS14080	COG3562	capsule polysaccharide
JG479_RS14095	COG3300	MHYT domain
JG479_RS14095	COG5001	Diguanylate cyclase
JG479_RS14105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JG479_RS14115	COG4181	ATPase activity
JG479_RS14130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JG479_RS14140	COG1227	inorganic diphosphatase activity
JG479_RS14145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JG479_RS14155	COG2003	Belongs to the UPF0758 family
JG479_RS14160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JG479_RS14170	COG4946	Tricorn protease homolog
JG479_RS14170	COG1506	peptidase
JG479_RS14170	COG0823	Involved in the tonB-independent uptake of proteins
JG479_RS14200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG479_RS14215	COG1522	sequence-specific DNA binding
JG479_RS14230	COG2199	diguanylate cyclase activity
JG479_RS14230	COG2203	Gaf domain
JG479_RS14235	COG2081	HI0933 family
JG479_RS14240	COG1404	Belongs to the peptidase S8 family
JG479_RS14245	COG0678	peroxiredoxin activity
JG479_RS14245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JG479_RS14250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JG479_RS14265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JG479_RS14270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JG479_RS14275	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JG479_RS14280	COG0142	geranyltranstransferase activity
JG479_RS14285	COG0039	L-malate dehydrogenase activity
JG479_RS14290	COG1438	arginine binding
JG479_RS14310	COG1840	ABC-type Fe3 transport system, periplasmic component
JG479_RS14320	COG3148	PFAM DTW domain containing protein
JG479_RS14325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JG479_RS14330	COG0508	dehydrogenase complex catalyzes the overall conversion of
JG479_RS14335	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JG479_RS14340	COG2186	Transcriptional regulator
JG479_RS14345	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JG479_RS14375	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JG479_RS14380	COG0237	dephospho-CoA kinase activity
JG479_RS14385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JG479_RS14390	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JG479_RS14400	COG0745	RESPONSE REGULATOR receiver
JG479_RS14405	COG2205	protein histidine kinase activity
JG479_RS14410	COG2267	carboxylic ester hydrolase activity
JG479_RS14420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JG479_RS14425	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JG479_RS14430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JG479_RS14435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JG479_RS14440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JG479_RS14445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JG479_RS14450	COG4942	peptidase
JG479_RS14455	COG0793	Belongs to the peptidase S41A family
JG479_RS14470	COG2177	Part of the ABC transporter FtsEX involved in
JG479_RS14475	COG2884	Cell division ATP-binding protein ftsE
JG479_RS14480	COG0552	protein localization to endoplasmic reticulum
JG479_RS14485	COG0742	ribosomal rna small subunit methyltransferase
JG479_RS14490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JG479_RS14505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JG479_RS14510	COG2264	protein methyltransferase activity
JG479_RS14515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JG479_RS14520	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JG479_RS14525	COG0138	bifunctional purine biosynthesis protein purh
JG479_RS14535	COG0151	Belongs to the GarS family
JG479_RS14540	COG5001	Diguanylate cyclase
JG479_RS14555	COG0123	including yeast histone deacetylase and acetoin utilization protein
JG479_RS14570	COG1280	lysine exporter protein (LysE YggA)
JG479_RS14605	COG2823	Periplasmic or secreted lipoprotein
JG479_RS14635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG479_RS14640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JG479_RS14645	COG1862	Preprotein translocase
JG479_RS14650	COG0343	queuine tRNA-ribosyltransferase activity
JG479_RS14655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JG479_RS14660	COG5002	protein histidine kinase activity
JG479_RS14660	COG5001	Diguanylate cyclase
JG479_RS14670	COG0583	DNA-binding transcription factor activity
JG479_RS14675	COG0306	phosphate transporter
JG479_RS14680	COG1392	Phosphate transport regulator
JG479_RS14690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JG479_RS14695	COG0573	inorganic phosphate transmembrane transporter activity
JG479_RS14705	COG2716	regulation of RNA biosynthetic process
JG479_RS14715	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG479_RS14740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JG479_RS14750	COG2824	Alkylphosphonate utilization operon protein PhnA
JG479_RS14760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JG479_RS14780	COG1388	LysM domain
JG479_RS14780	COG0741	lytic transglycosylase activity
JG479_RS14795	COG3618	amidohydrolase
JG479_RS14805	COG4948	Mandelate Racemase Muconate Lactonizing
JG479_RS14850	COG3850	Histidine kinase
JG479_RS14850	COG2205	protein histidine kinase activity
JG479_RS14850	COG3437	response regulator, receiver
JG479_RS14850	COG4999	Histidine kinase
JG479_RS14860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JG479_RS14865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JG479_RS14875	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JG479_RS14880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JG479_RS14885	COG0330	HflC and HflK could
JG479_RS14890	COG0330	HflC and HflK could
JG479_RS14895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JG479_RS14900	COG1923	regulation of RNA biosynthetic process
JG479_RS14905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JG479_RS14910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JG479_RS14915	COG0860	N-Acetylmuramoyl-L-alanine amidase
JG479_RS14920	COG0802	atpase or kinase
JG479_RS14925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JG479_RS14930	COG0255	Belongs to the universal ribosomal protein uL29 family
JG479_RS14935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JG479_RS14940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JG479_RS14945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JG479_RS14950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JG479_RS14955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JG479_RS14960	COG0089	rRNA binding
JG479_RS14965	COG0088	Forms part of the polypeptide exit tunnel
JG479_RS14970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JG479_RS14975	COG0051	transcription antitermination factor activity, RNA binding
JG479_RS14980	COG2937	Belongs to the GPAT DAPAT family
JG479_RS14985	COG1946	Acyl-CoA thioesterase
JG479_RS15010	COG2031	fatty acid transporter
JG479_RS15050	COG1253	flavin adenine dinucleotide binding
JG479_RS15065	COG0606	chelatase, subunit chli
JG479_RS15070	COG2860	membrane
JG479_RS15090	COG1218	3'(2'),5'-bisphosphate nucleotidase
JG479_RS15095	COG0494	nUDIX hydrolase
JG479_RS15100	COG1011	Hydrolase
JG479_RS15110	COG3112	Uncharacterised protein family (UPF0231)
JG479_RS15120	COG0210	DNA helicase
JG479_RS15125	COG1444	tRNA N-acetyltransferase activity
JG479_RS15150	COG0203	ribosomal protein L17
JG479_RS15155	COG0202	RNA polymerase activity
JG479_RS15160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JG479_RS15165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JG479_RS15170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JG479_RS15175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JG479_RS15180	COG0201	protein transport
JG479_RS15185	COG0200	Binds to the 23S rRNA
JG479_RS15190	COG1841	ribosomal large subunit assembly
JG479_RS15195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JG479_RS15200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JG479_RS15205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JG479_RS15210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JG479_RS15215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JG479_RS15220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JG479_RS15225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JG479_RS15230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JG479_RS15265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS15270	COG1136	(ABC) transporter
JG479_RS15275	COG0577	efflux transmembrane transporter activity
JG479_RS15295	COG4555	ABC transporter
JG479_RS15305	COG0640	Transcriptional regulator
JG479_RS15350	COG1132	(ABC) transporter
JG479_RS15355	COG2885	chlorophyll binding
JG479_RS15365	COG0668	transmembrane transport
JG479_RS15370	COG0204	Acyl-transferase
JG479_RS15375	COG0204	Acyl-transferase
JG479_RS15380	COG1166	arginine decarboxylase activity
JG479_RS15385	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JG479_RS15405	COG1082	Xylose isomerase domain protein TIM barrel
JG479_RS15440	COG4372	Transposase
JG479_RS15445	COG2801	Transposase and inactivated derivatives
JG479_RS15465	COG1276	copper resistance
JG479_RS15480	COG2132	Multicopper oxidase
JG479_RS15485	COG0745	RESPONSE REGULATOR receiver
JG479_RS15490	COG5002	protein histidine kinase activity
JG479_RS15500	COG3436	PFAM IS66 Orf2 family protein
JG479_RS15550	COG1230	cation diffusion facilitator family transporter
JG479_RS15560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JG479_RS15580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JG479_RS15595	COG1061	Type III restriction enzyme res subunit
JG479_RS15620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JG479_RS15655	COG2183	response to ionizing radiation
JG479_RS15670	COG0596	Alpha beta hydrolase
JG479_RS15675	COG1040	competence protein
JG479_RS15685	COG0316	Belongs to the HesB IscA family
JG479_RS15685	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JG479_RS15695	COG0534	Mate efflux family protein
JG479_RS15700	COG0726	polysaccharide deacetylase
JG479_RS15705	COG2201	protein-glutamate methylesterase activity
JG479_RS15710	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JG479_RS15715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JG479_RS15725	COG0835	chemotaxis
JG479_RS15730	COG2198	Histidine kinase
JG479_RS15730	COG0643	Histidine kinase
JG479_RS15735	COG0745	RESPONSE REGULATOR receiver
JG479_RS15750	COG0109	protoheme IX farnesyltransferase activity
JG479_RS15820	COG0484	heat shock protein binding
JG479_RS15840	COG1017	nitric oxide dioxygenase activity
JG479_RS15840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JG479_RS15850	COG3604	Transcriptional regulator
JG479_RS15855	COG0583	DNA-binding transcription factor activity
JG479_RS15860	COG0431	NADPH-dependent FMN reductase
JG479_RS15895	COG0248	Ppx GppA phosphatase
JG479_RS15900	COG0513	Belongs to the DEAD box helicase family
JG479_RS15905	COG3118	belongs to the thioredoxin family
JG479_RS15915	COG0784	Response regulator, receiver
JG479_RS15915	COG2198	Histidine kinase
JG479_RS15915	COG2205	protein histidine kinase activity
JG479_RS15925	COG0513	Belongs to the DEAD box helicase family
JG479_RS15930	COG4774	siderophore transport
JG479_RS15945	COG2354	Protein conserved in bacteria
JG479_RS15960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JG479_RS15970	COG4109	DRTGG domain
JG479_RS15975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JG479_RS15980	COG2205	protein histidine kinase activity
JG479_RS15980	COG0784	Response regulator, receiver
JG479_RS15990	COG2959	enzyme of heme biosynthesis
JG479_RS15995	COG0181	hydroxymethylbilane synthase activity
JG479_RS16005	COG0400	carboxylic ester hydrolase activity
JG479_RS16010	COG1965	Belongs to the frataxin family
JG479_RS16020	COG0019	diaminopimelate decarboxylase activity
JG479_RS16025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JG479_RS16035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JG479_RS16040	COG1011	Hydrolase
JG479_RS16065	COG1187	pseudouridine synthase activity
JG479_RS16095	COG3153	acetyltransferase
JG479_RS16095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JG479_RS16100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JG479_RS16110	COG1944	ATP diphosphatase activity
JG479_RS16120	COG3132	Protein of unknown function, DUF480
JG479_RS16125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JG479_RS16135	COG0302	gtp cyclohydrolase
JG479_RS16140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JG479_RS16145	COG1238	metal cluster binding
JG479_RS16165	COG0745	RESPONSE REGULATOR receiver
JG479_RS16170	COG2198	Histidine kinase
JG479_RS16170	COG2205	protein histidine kinase activity
JG479_RS16170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG479_RS16170	COG0784	Response regulator, receiver
JG479_RS16175	COG1770	oligopeptidase
JG479_RS16250	COG3428	Bacterial PH domain
JG479_RS16260	COG0676	glucose-6-phosphate 1-epimerase activity
JG479_RS16275	COG2832	Protein of unknown function (DUF454)
JG479_RS16340	COG2188	Transcriptional regulator
JG479_RS16350	COG1278	Cold shock
JG479_RS16355	COG1278	Cold shock
JG479_RS16360	COG1278	Cold shock
JG479_RS16385	COG4771	TonB-dependent receptor
JG479_RS16400	COG0513	Belongs to the DEAD box helicase family
JG479_RS16410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JG479_RS16415	COG1349	DNA-binding transcription factor activity
JG479_RS16425	COG0110	maltose O-acetyltransferase activity
JG479_RS16460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JG479_RS16465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JG479_RS16470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JG479_RS16475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JG479_RS16480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JG479_RS16485	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JG479_RS16490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JG479_RS16500	COG0356	it plays a direct role in the translocation of protons across the membrane
JG479_RS16510	COG1475	DNA binding
JG479_RS16515	COG1192	Involved in chromosome partitioning
JG479_RS16520	COG0357	Ribosomal RNA small subunit methyltransferase G
JG479_RS16525	COG0445	tRNA wobble uridine modification
JG479_RS16530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JG479_RS16535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JG479_RS16540	COG0706	membrane insertase activity
JG479_RS16545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JG479_RS16550	COG0594	ribonuclease P activity
JG479_RS16555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JG479_RS16575	COG0217	transcriptional regulatory protein
JG479_RS16580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JG479_RS16605	COG3706	GGDEF domain
JG479_RS16625	COG4771	TonB-dependent receptor
JG479_RS16630	COG4558	Periplasmic binding protein
JG479_RS16635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JG479_RS16640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JG479_RS16670	COG0583	DNA-binding transcription factor activity
JG479_RS16680	COG3384	dioxygenase
JG479_RS16685	COG0583	DNA-binding transcription factor activity
JG479_RS16690	COG0583	DNA-binding transcription factor activity
JG479_RS16730	COG1322	Protein conserved in bacteria
JG479_RS16735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JG479_RS16745	COG1192	Involved in chromosome partitioning
JG479_RS16760	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JG479_RS16765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JG479_RS16770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JG479_RS16770	COG0574	Belongs to the PEP-utilizing enzyme family
JG479_RS16780	COG0277	FAD linked oxidase domain protein
JG479_RS16780	COG0247	lactate metabolic process
JG479_RS16785	COG3263	regulation of cellular component size
JG479_RS16810	COG1115	amino acid carrier protein
JG479_RS16820	COG2423	ornithine cyclodeaminase activity
JG479_RS16835	COG2801	Transposase and inactivated derivatives
JG479_RS16845	COG4667	esterase of the alpha-beta hydrolase superfamily
JG479_RS16850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JG479_RS16885	COG4895	conserved protein (DUF2196)
JG479_RS16910	COG5001	Diguanylate cyclase
JG479_RS16910	COG3300	MHYT domain
JG479_RS16935	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JG479_RS16940	COG0848	biopolymer transport protein
JG479_RS16945	COG0811	peptide transport
JG479_RS16950	COG0811	peptide transport
JG479_RS16990	COG2983	Belongs to the UPF0260 family
JG479_RS17000	COG1228	amidohydrolase
JG479_RS17020	COG2951	lytic endotransglycosylase activity
JG479_RS17025	COG3100	YcgL domain-containing protein
JG479_RS17030	COG0850	regulation of cytokinetic process
JG479_RS17035	COG2894	cell division
JG479_RS17040	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JG479_RS17055	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JG479_RS17060	COG0318	PFAM AMP-dependent synthetase and ligase
JG479_RS17070	COG1785	Belongs to the alkaline phosphatase family
JG479_RS17080	COG1214	PFAM Peptidase M22, glycoprotease
JG479_RS17085	COG1199	ATP-dependent helicase activity
JG479_RS17095	COG0672	)-iron permease
JG479_RS17105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JG479_RS17110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JG479_RS17115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JG479_RS17120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JG479_RS17120	COG0131	Imidazoleglycerol-phosphate dehydratase
JG479_RS17125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JG479_RS17130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JG479_RS17135	COG0107	imidazoleglycerol-phosphate synthase activity
JG479_RS17140	COG0140	phosphoribosyl-ATP diphosphatase activity
JG479_RS17140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JG479_RS17155	COG3265	gluconokinase activity
JG479_RS17160	COG2610	gluconate transmembrane transporter activity
JG479_RS17165	COG1609	Transcriptional regulator
JG479_RS17200	COG1611	Belongs to the LOG family
JG479_RS17205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JG479_RS17220	COG0473	3-isopropylmalate dehydrogenase activity
JG479_RS17230	COG0028	Belongs to the TPP enzyme family
JG479_RS17235	COG0440	acetolactate synthase activity
JG479_RS17260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JG479_RS17275	COG4221	oxidoreductase activity
JG479_RS17285	COG0415	Belongs to the DNA photolyase family
JG479_RS17300	COG1595	DNA-templated transcription, initiation
JG479_RS17320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JG479_RS17330	COG4771	TonB-dependent receptor
JG479_RS17335	COG1272	protein, Hemolysin III
JG479_RS17370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS17375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JG479_RS17380	COG0653	protein targeting
JG479_RS17400	COG1187	pseudouridine synthase activity
JG479_RS17405	COG2311	Membrane
JG479_RS17410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JG479_RS17425	COG0058	SHG alpha-glucan phosphorylase activity
JG479_RS17435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JG479_RS17440	COG1640	4-alpha-glucanotransferase
JG479_RS17465	COG1522	sequence-specific DNA binding
JG479_RS17470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JG479_RS17480	COG1012	belongs to the aldehyde dehydrogenase family
JG479_RS17505	COG1309	transcriptional regulator
JG479_RS17510	COG1012	belongs to the aldehyde dehydrogenase family
JG479_RS17540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JG479_RS17545	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JG479_RS17550	COG0154	amidase activity
JG479_RS17555	COG0513	Belongs to the DEAD box helicase family
JG479_RS17560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JG479_RS17600	COG0656	L-ascorbic acid biosynthetic process
JG479_RS17605	COG2814	Major facilitator Superfamily
JG479_RS17610	COG0583	DNA-binding transcription factor activity
JG479_RS17615	COG2223	nitrite transmembrane transporter activity
JG479_RS17620	COG2199	diguanylate cyclase activity
JG479_RS17620	COG2203	Gaf domain
JG479_RS17635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JG479_RS17650	COG4206	TonB-dependent receptor
JG479_RS17655	COG0366	Alpha amylase catalytic
JG479_RS17660	COG1215	transferase activity, transferring glycosyl groups
JG479_RS17665	COG3769	mannosylglycerate metabolic process
JG479_RS17675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JG479_RS17800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JG479_RS17845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JG479_RS17855	COG2199	diguanylate cyclase activity
JG479_RS17880	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JG479_RS17900	COG0471	metal ion transport
JG479_RS17910	COG2204	response regulator
JG479_RS17915	COG4191	Histidine kinase
JG479_RS17925	COG2205	protein histidine kinase activity
JG479_RS17925	COG2198	Histidine kinase
JG479_RS17925	COG0784	Response regulator, receiver
JG479_RS17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG479_RS17940	COG0484	heat shock protein binding
JG479_RS17945	COG0443	Heat shock 70 kDa protein
JG479_RS17960	COG2995	paraquat-inducible protein a
JG479_RS17965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JG479_RS17965	COG3008	intermembrane lipid transfer
JG479_RS17975	COG1757	Na H antiporter
JG479_RS18035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JG479_RS18040	COG0625	glutathione transferase activity
JG479_RS18055	COG4628	conserved protein (DUF2132)
JG479_RS18060	COG1803	Methylglyoxal synthase
JG479_RS18060	COG1597	lipid kinase activity
JG479_RS18065	COG1595	DNA-templated transcription, initiation
JG479_RS18115	COG1253	flavin adenine dinucleotide binding
JG479_RS18125	COG0010	Belongs to the arginase family
JG479_RS18130	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JG479_RS18135	COG0295	cytidine deaminase activity
JG479_RS18140	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JG479_RS18175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JG479_RS18185	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JG479_RS18200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JG479_RS18205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JG479_RS18210	COG0346	lactoylglutathione lyase activity
JG479_RS18215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JG479_RS18235	COG0457	Tetratricopeptide repeat
JG479_RS18245	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JG479_RS18250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JG479_RS18255	COG1435	thymidine kinase activity
JG479_RS18275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JG479_RS18290	COG5002	protein histidine kinase activity
JG479_RS18290	COG2205	protein histidine kinase activity
JG479_RS18290	COG0784	Response regulator, receiver
JG479_RS18295	COG1230	cation diffusion facilitator family transporter
JG479_RS18310	COG2193	ferroxidase activity
JG479_RS18315	COG2193	ferroxidase activity
JG479_RS18320	COG2906	2 iron, 2 sulfur cluster binding
JG479_RS18325	COG2119	membrane
JG479_RS18335	COG0840	transmembrane signaling receptor activity
JG479_RS18345	COG5001	Diguanylate cyclase
JG479_RS18345	COG1716	ATPase activity
JG479_RS18355	COG5001	Diguanylate cyclase
JG479_RS18355	COG3706	GGDEF domain
JG479_RS18355	COG4251	negative regulation of phosphorylation
JG479_RS18355	COG2203	Gaf domain
JG479_RS18375	COG4667	esterase of the alpha-beta hydrolase superfamily
JG479_RS18405	COG2205	protein histidine kinase activity
JG479_RS18405	COG0784	Response regulator, receiver
JG479_RS18415	COG3634	alkyl hydroperoxide reductase activity
JG479_RS18450	COG0673	inositol 2-dehydrogenase activity
JG479_RS18455	COG2186	Transcriptional regulator
JG479_RS18465	COG2814	Major facilitator Superfamily
JG479_RS18470	COG1902	pentaerythritol trinitrate reductase activity
JG479_RS18475	COG4771	TonB-dependent receptor
JG479_RS18480	COG0457	Tetratricopeptide repeat
JG479_RS18565	COG1280	lysine exporter protein (LysE YggA)
JG479_RS18580	COG1609	Transcriptional regulator
JG479_RS18600	COG0028	Belongs to the TPP enzyme family
JG479_RS18605	COG0564	pseudouridine synthase activity
JG479_RS18610	COG2199	diguanylate cyclase activity
JG479_RS18635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JG479_RS18660	COG4134	Bacterial extracellular solute-binding protein
JG479_RS18670	COG4136	ATPase activity
JG479_RS18675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JG479_RS18705	COG1609	Transcriptional regulator
JG479_RS18745	COG0583	DNA-binding transcription factor activity
JG479_RS18770	COG1966	Carbon starvation protein
JG479_RS18775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JG479_RS18780	COG0246	Mannitol dehydrogenase
JG479_RS18790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JG479_RS18795	COG0753	catalase activity
JG479_RS18810	COG1131	(ABC) transporter
JG479_RS18815	COG2972	Histidine kinase
JG479_RS18820	COG3279	Response regulator of the LytR AlgR family
JG479_RS18830	COG1309	transcriptional regulator
JG479_RS18835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JG479_RS18840	COG0154	amidase activity
JG479_RS18850	COG0730	response to heat
JG479_RS18855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JG479_RS18870	COG3813	Protein conserved in bacteria
JG479_RS18880	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JG479_RS18925	COG0471	metal ion transport
JG479_RS18935	COG2860	membrane
JG479_RS18970	COG2233	PERMEase
JG479_RS18980	COG1079	Belongs to the binding-protein-dependent transport system permease family
JG479_RS18985	COG4603	Belongs to the binding-protein-dependent transport system permease family
JG479_RS19000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JG479_RS19015	COG2351	hydroxyisourate hydrolase activity
JG479_RS19020	COG0402	S-adenosylhomocysteine deaminase activity
JG479_RS19035	COG2197	response regulator
JG479_RS19045	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JG479_RS19075	COG0705	Rhomboid family
JG479_RS19115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JG479_RS19120	COG0640	Transcriptional regulator
JG479_RS19125	COG1764	response to oxidative stress
JG479_RS19130	COG1846	Transcriptional regulator
JG479_RS19140	COG3724	N-succinylarginine dihydrolase activity
JG479_RS19145	COG0668	transmembrane transport
JG479_RS19190	COG1621	beta-fructofuranosidase activity
JG479_RS19200	COG2211	Major facilitator Superfamily
JG479_RS19205	COG0745	RESPONSE REGULATOR receiver
JG479_RS19210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JG479_RS19280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JG479_RS19285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JG479_RS19290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JG479_RS19305	COG2255	four-way junction helicase activity
JG479_RS19320	COG2801	Transposase and inactivated derivatives
JG479_RS19340	COG1479	Protein of unknown function DUF262
JG479_RS19405	COG4206	TonB-dependent receptor
JG479_RS19420	COG0826	peptidase U32
JG479_RS19425	COG0105	UTP biosynthetic process
JG479_RS19430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JG479_RS19445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JG479_RS19450	COG0124	histidyl-tRNA synthetase
JG479_RS19455	COG2976	Protein conserved in bacteria
JG479_RS19460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JG479_RS19465	COG1160	GTP binding
JG479_RS19485	COG0415	Belongs to the DNA photolyase family
JG479_RS19490	COG2855	membrane
JG479_RS19495	COG0583	DNA-binding transcription factor activity
JG479_RS19575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JG479_RS19580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JG479_RS19585	COG2130	NADP-dependent
JG479_RS19595	COG0840	transmembrane signaling receptor activity
JG479_RS19605	COG0514	ATP-dependent DNA helicase (RecQ)
JG479_RS19610	COG1252	NADH dehydrogenase
JG479_RS19650	COG0270	DNA (cytosine-5-)-methyltransferase activity
JG479_RS19690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JG479_RS19695	COG0488	(ABC) transporter
JG479_RS19700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JG479_RS19715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JG479_RS19740	COG2207	Transcriptional regulator
JG479_RS19745	COG4303	Ethanolamine ammonia lyase large subunit
JG479_RS19750	COG4302	ethanolamine ammonia-lyase activity
JG479_RS19755	COG0531	amino acid
JG479_RS19770	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JG479_RS19780	COG0813	purine-nucleoside phosphorylase activity
JG479_RS19785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JG479_RS19790	COG0572	uridine kinase
JG479_RS19795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JG479_RS19805	COG1278	Cold shock
JG479_RS19830	COG0745	RESPONSE REGULATOR receiver
JG479_RS19850	COG1022	Amp-dependent synthetase and ligase
JG479_RS19875	COG1846	Transcriptional regulator
JG479_RS19890	COG3135	benzoate transporter
JG479_RS19915	COG0745	RESPONSE REGULATOR receiver
JG479_RS19920	COG0642	Histidine kinase
JG479_RS19940	COG0385	Bile acid
JG479_RS19945	COG1573	uracil-dna glycosylase
JG479_RS19970	COG3040	lipid binding
JG479_RS19975	COG1671	Belongs to the UPF0178 family
JG479_RS20000	COG0420	3'-5' exonuclease activity