locus-tag	class	description
FLM47_RS00010	COG0592	DNA-directed DNA polymerase activity
FLM47_RS00020	COG0187	DNA topoisomerase II activity
FLM47_RS00050	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLM47_RS00050	COG1024	Enoyl-CoA hydratase
FLM47_RS00055	COG0741	lytic transglycosylase activity
FLM47_RS00060	COG0006	proline dipeptidase activity
FLM47_RS00065	COG1739	Uncharacterized protein family UPF0029
FLM47_RS00070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLM47_RS00100	COG0569	domain protein
FLM47_RS00105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLM47_RS00105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLM47_RS00125	COG0758	DNA mediated transformation
FLM47_RS00145	COG0408	coproporphyrinogen oxidase activity
FLM47_RS00155	COG2346	COG2346, Truncated hemoglobins
FLM47_RS00170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLM47_RS00210	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FLM47_RS00270	COG1522	sequence-specific DNA binding
FLM47_RS00325	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FLM47_RS00355	COG1404	Belongs to the peptidase S8 family
FLM47_RS00360	COG1770	oligopeptidase
FLM47_RS00365	COG5002	protein histidine kinase activity
FLM47_RS00365	COG0784	Response regulator, receiver
FLM47_RS00370	COG0745	RESPONSE REGULATOR receiver
FLM47_RS00390	COG1238	metal cluster binding
FLM47_RS00395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLM47_RS00420	COG2205	protein histidine kinase activity
FLM47_RS00420	COG0784	Response regulator, receiver
FLM47_RS00420	COG5002	protein histidine kinase activity
FLM47_RS00425	COG1944	ATP diphosphatase activity
FLM47_RS00435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLM47_RS00440	COG3153	acetyltransferase
FLM47_RS00440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLM47_RS00470	COG1187	pseudouridine synthase activity
FLM47_RS00495	COG1011	Hydrolase
FLM47_RS00515	COG0019	diaminopimelate decarboxylase activity
FLM47_RS00540	COG0181	hydroxymethylbilane synthase activity
FLM47_RS00545	COG2959	enzyme of heme biosynthesis
FLM47_RS00580	COG0840	transmembrane signaling receptor activity
FLM47_RS00590	COG2354	Protein conserved in bacteria
FLM47_RS00600	COG4774	siderophore transport
FLM47_RS00605	COG0513	Belongs to the DEAD box helicase family
FLM47_RS00615	COG2205	protein histidine kinase activity
FLM47_RS00615	COG0784	Response regulator, receiver
FLM47_RS00615	COG5002	protein histidine kinase activity
FLM47_RS00625	COG3118	belongs to the thioredoxin family
FLM47_RS00665	COG1444	tRNA N-acetyltransferase activity
FLM47_RS00670	COG0210	DNA helicase
FLM47_RS00680	COG3112	Uncharacterised protein family (UPF0231)
FLM47_RS00690	COG1011	Hydrolase
FLM47_RS00695	COG0494	nUDIX hydrolase
FLM47_RS00700	COG1218	3'(2'),5'-bisphosphate nucleotidase
FLM47_RS00725	COG0606	chelatase, subunit chli
FLM47_RS00735	COG1506	peptidase
FLM47_RS00735	COG0823	Involved in the tonB-independent uptake of proteins
FLM47_RS00740	COG1253	flavin adenine dinucleotide binding
FLM47_RS00745	COG2199	diguanylate cyclase activity
FLM47_RS00745	COG2200	EAL domain
FLM47_RS00745	COG2202	Pas domain
FLM47_RS00755	COG2031	fatty acid transporter
FLM47_RS00760	COG0835	chemotaxis
FLM47_RS00760	COG0784	Response regulator, receiver
FLM47_RS00785	COG1946	Acyl-CoA thioesterase
FLM47_RS00820	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLM47_RS00860	COG2356	endonuclease I
FLM47_RS00890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLM47_RS00925	COG3852	Histidine kinase
FLM47_RS00935	COG0174	glutamine synthetase
FLM47_RS00980	COG0456	acetyltransferase
FLM47_RS00985	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FLM47_RS00995	COG0019	diaminopimelate decarboxylase activity
FLM47_RS01005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLM47_RS01020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FLM47_RS01020	COG2885	chlorophyll binding
FLM47_RS01025	COG1049	propionate catabolic process, 2-methylcitrate cycle
FLM47_RS01035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLM47_RS01075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLM47_RS01095	COG1765	OsmC-like protein
FLM47_RS01110	COG0814	amino acid
FLM47_RS01115	COG2267	carboxylic ester hydrolase activity
FLM47_RS01130	COG1218	3'(2'),5'-bisphosphate nucleotidase
FLM47_RS01135	COG0529	Catalyzes the synthesis of activated sulfate
FLM47_RS01140	COG3273	potassium ion transport
FLM47_RS01140	COG0471	metal ion transport
FLM47_RS01145	COG2895	sulfate adenylyltransferase (ATP) activity
FLM47_RS01160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FLM47_RS01185	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLM47_RS01190	COG0250	Participates in transcription elongation, termination and antitermination
FLM47_RS01260	COG0784	Response regulator, receiver
FLM47_RS01260	COG2205	protein histidine kinase activity
FLM47_RS01265	COG1119	ATPase activity
FLM47_RS01275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FLM47_RS01280	COG2194	sulfuric ester hydrolase activity
FLM47_RS01300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLM47_RS01315	COG0288	reversible hydration of carbon dioxide
FLM47_RS01345	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FLM47_RS01350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLM47_RS01350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLM47_RS01375	COG3078	GTPase activator activity
FLM47_RS01385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLM47_RS01395	COG0312	modulator of DNA gyrase
FLM47_RS01405	COG3590	peptidase
FLM47_RS01410	COG0494	nUDIX hydrolase
FLM47_RS01420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLM47_RS01425	COG2986	histidine ammonia-lyase
FLM47_RS01480	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLM47_RS01485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLM47_RS01495	COG0281	malic enzyme
FLM47_RS01505	COG0626	cystathionine gamma-synthase activity
FLM47_RS01510	COG0527	aspartate kinase activity
FLM47_RS01510	COG0460	homoserine dehydrogenase
FLM47_RS01515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FLM47_RS01520	COG1077	Cell shape determining protein MreB Mrl
FLM47_RS01560	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FLM47_RS01575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLM47_RS01585	COG0180	Tryptophanyl-tRNA synthetase
FLM47_RS01590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLM47_RS01595	COG2814	Major facilitator Superfamily
FLM47_RS01600	COG0629	single-stranded DNA binding
FLM47_RS01610	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FLM47_RS01615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FLM47_RS01620	COG1077	Cell shape determining protein MreB Mrl
FLM47_RS01625	COG1792	Involved in formation and maintenance of cell shape
FLM47_RS01630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FLM47_RS01640	COG1530	ribonuclease E activity
FLM47_RS01645	COG3164	Protein of unknown function
FLM47_RS01650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLM47_RS01655	COG0312	modulator of DNA gyrase
FLM47_RS01660	COG0583	DNA-binding transcription factor activity
FLM47_RS01670	COG1902	pentaerythritol trinitrate reductase activity
FLM47_RS01675	COG1881	PFAM PEBP family protein
FLM47_RS01695	COG4181	ATPase activity
FLM47_RS01705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FLM47_RS01715	COG5001	Diguanylate cyclase
FLM47_RS01715	COG3300	MHYT domain
FLM47_RS01730	COG3306	glycosyltransferase involved in LPS biosynthesis
FLM47_RS01765	COG1187	pseudouridine synthase activity
FLM47_RS01770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FLM47_RS01775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FLM47_RS01795	COG1509	lysine 2,3-aminomutase activity
FLM47_RS01810	COG1629	transport
FLM47_RS01810	COG4774	siderophore transport
FLM47_RS01850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLM47_RS01885	COG0432	Pfam Uncharacterised protein family UPF0047
FLM47_RS01895	COG0735	belongs to the Fur family
FLM47_RS01900	COG2095	MarC family integral membrane protein
FLM47_RS01910	COG1842	Phage shock protein A
FLM47_RS01925	COG2847	Copper chaperone PCu(A)C
FLM47_RS01950	COG1032	radical SAM domain protein
FLM47_RS01955	COG2239	Acts as a magnesium transporter
FLM47_RS01960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM47_RS01970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLM47_RS01980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FLM47_RS01985	COG1137	ATPase activity
FLM47_RS02000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FLM47_RS02005	COG0517	IMP dehydrogenase activity
FLM47_RS02005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLM47_RS02015	COG1127	ABC transporter
FLM47_RS02020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FLM47_RS02025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FLM47_RS02030	COG2854	intermembrane phospholipid transfer
FLM47_RS02035	COG3113	response to antibiotic
FLM47_RS02040	COG5007	Belongs to the BolA IbaG family
FLM47_RS02055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLM47_RS02065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FLM47_RS02070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLM47_RS02075	COG0339	signal peptide processing
FLM47_RS02105	COG0822	iron-sulfur transferase activity
FLM47_RS02110	COG0316	Belongs to the HesB IscA family
FLM47_RS02115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FLM47_RS02145	COG0668	transmembrane transport
FLM47_RS02150	COG3137	Salt-induced outer membrane protein
FLM47_RS02165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLM47_RS02170	COG1459	type II secretion system
FLM47_RS02250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLM47_RS02265	COG0463	Glycosyl transferase, family 2
FLM47_RS02295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FLM47_RS02300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLM47_RS02310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FLM47_RS02315	COG1227	inorganic diphosphatase activity
FLM47_RS02325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLM47_RS02335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FLM47_RS02345	COG0723	plastoquinol--plastocyanin reductase activity
FLM47_RS02350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLM47_RS02355	COG2857	Cytochrome c1
FLM47_RS02360	COG0625	glutathione transferase activity
FLM47_RS02365	COG2969	positive regulation of protein catabolic process
FLM47_RS02370	COG2823	Periplasmic or secreted lipoprotein
FLM47_RS02375	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FLM47_RS02385	COG3107	peptidoglycan biosynthetic process
FLM47_RS02390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLM47_RS02405	COG1295	ribonuclease BN
FLM47_RS02470	COG0768	penicillin binding
FLM47_RS02475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLM47_RS02480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLM47_RS02515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FLM47_RS02520	COG0849	cell division
FLM47_RS02525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLM47_RS02535	COG1011	Hydrolase
FLM47_RS02545	COG3954	Phosphoribulokinase
FLM47_RS02575	COG0625	glutathione transferase activity
FLM47_RS02590	COG1247	-acetyltransferase
FLM47_RS02595	COG2205	protein histidine kinase activity
FLM47_RS02595	COG0784	Response regulator, receiver
FLM47_RS02595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM47_RS02595	COG2198	Histidine kinase
FLM47_RS02615	COG0584	glycerophosphoryl diester phosphodiesterase
FLM47_RS02625	COG4585	Histidine kinase
FLM47_RS02630	COG2197	response regulator
FLM47_RS02640	COG0557	exoribonuclease II activity
FLM47_RS02645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLM47_RS02650	COG4774	siderophore transport
FLM47_RS02655	COG0583	DNA-binding transcription factor activity
FLM47_RS02695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLM47_RS02715	COG1715	Restriction endonuclease
FLM47_RS02805	COG0840	transmembrane signaling receptor activity
FLM47_RS02850	COG0753	catalase activity
FLM47_RS02880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM47_RS02890	COG3706	GGDEF domain
FLM47_RS02895	COG1228	amidohydrolase
FLM47_RS02925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLM47_RS02940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLM47_RS02950	COG2137	regulation of response to DNA damage stimulus
FLM47_RS02985	COG3630	sodium ion export across plasma membrane
FLM47_RS03000	COG4989	oxidoreductase activity
FLM47_RS03040	COG2198	Histidine kinase
FLM47_RS03040	COG5002	protein histidine kinase activity
FLM47_RS03040	COG0784	Response regulator, receiver
FLM47_RS03045	COG0745	RESPONSE REGULATOR receiver
FLM47_RS03050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM47_RS03050	COG4191	Histidine kinase
FLM47_RS03065	COG1194	a g-specific adenine glycosylase
FLM47_RS03075	COG5002	protein histidine kinase activity
FLM47_RS03075	COG2205	protein histidine kinase activity
FLM47_RS03075	COG0784	Response regulator, receiver
FLM47_RS03120	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FLM47_RS03145	COG3079	Belongs to the UPF0149 family
FLM47_RS03150	COG0006	proline dipeptidase activity
FLM47_RS03155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLM47_RS03160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLM47_RS03175	COG2965	DNA replication, synthesis of RNA primer
FLM47_RS03190	COG1595	DNA-templated transcription, initiation
FLM47_RS03205	COG0305	Participates in initiation and elongation during chromosome replication
FLM47_RS03245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FLM47_RS03260	COG2927	DNA polymerase III (CHI subunit)
FLM47_RS03265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLM47_RS03270	COG0795	lipopolysaccharide-transporting ATPase activity
FLM47_RS03275	COG0795	lipopolysaccharide-transporting ATPase activity
FLM47_RS03295	COG1283	sodium-dependent phosphate transmembrane transporter activity
FLM47_RS03330	COG1012	belongs to the aldehyde dehydrogenase family
FLM47_RS03355	COG2204	response regulator
FLM47_RS03365	COG4251	negative regulation of phosphorylation
FLM47_RS03370	COG0784	Response regulator, receiver
FLM47_RS03375	COG2198	Histidine kinase
FLM47_RS03375	COG0784	Response regulator, receiver
FLM47_RS03375	COG5002	protein histidine kinase activity
FLM47_RS03380	COG1609	Transcriptional regulator
FLM47_RS03385	COG2211	Major facilitator Superfamily
FLM47_RS03405	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLM47_RS03415	COG0667	Aldo Keto reductase
FLM47_RS03455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLM47_RS03495	COG1061	Type III restriction enzyme res subunit
FLM47_RS03510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FLM47_RS03555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLM47_RS03595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM47_RS03595	COG4191	Histidine kinase
FLM47_RS03600	COG4565	transcriptional regulatory protein
FLM47_RS03615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLM47_RS03630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLM47_RS03630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLM47_RS03665	COG3706	GGDEF domain
FLM47_RS03675	COG0142	geranyltranstransferase activity
FLM47_RS03685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLM47_RS03690	COG2885	chlorophyll binding
FLM47_RS03700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLM47_RS03705	COG1473	amidohydrolase
FLM47_RS03710	COG3118	belongs to the thioredoxin family
FLM47_RS03735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM47_RS03770	COG3784	Protein of unknown function (DUF1318)
FLM47_RS03780	COG1519	Transferase
FLM47_RS03785	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FLM47_RS03805	COG0438	transferase activity, transferring glycosyl groups
FLM47_RS03810	COG3642	lipopolysaccharide core region biosynthetic process
FLM47_RS03815	COG0859	PFAM glycosyl transferase family 9
FLM47_RS03820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FLM47_RS03840	COG0705	Rhomboid family
FLM47_RS03845	COG1580	Controls the rotational direction of flagella during chemotaxis
FLM47_RS03865	COG0583	DNA-binding transcription factor activity
FLM47_RS03895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLM47_RS03910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLM47_RS03915	COG0163	prenyltransferase activity
FLM47_RS03920	COG1131	(ABC) transporter
FLM47_RS03925	COG0842	Transport permease protein
FLM47_RS03930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FLM47_RS03940	COG0076	glutamate decarboxylase activity
FLM47_RS03950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLM47_RS03970	COG0165	Argininosuccinate lyase
FLM47_RS03970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FLM47_RS04000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLM47_RS04000	COG0301	tRNA thio-modification
FLM47_RS04005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLM47_RS04020	COG4206	TonB-dependent receptor
FLM47_RS04030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM47_RS04060	COG3267	Type II secretory pathway component ExeA
FLM47_RS04060	COG3409	Peptidoglycan-binding domain 1 protein
FLM47_RS04075	COG0506	proline dehydrogenase activity
FLM47_RS04075	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FLM47_RS04075	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FLM47_RS04080	COG1522	sequence-specific DNA binding
FLM47_RS04085	COG4991	sh3 domain protein
FLM47_RS04090	COG3025	triphosphatase activity
FLM47_RS04105	COG0745	RESPONSE REGULATOR receiver
FLM47_RS04115	COG0004	ammonium transporteR
FLM47_RS04120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLM47_RS04135	COG0840	transmembrane signaling receptor activity
FLM47_RS04145	COG0540	Belongs to the ATCase OTCase family
FLM47_RS04175	COG2211	Major facilitator Superfamily
FLM47_RS04200	COG0271	Belongs to the BolA IbaG family
FLM47_RS04215	COG1805	sodium ion transport
FLM47_RS04220	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FLM47_RS04235	COG2871	sodium ion transport
FLM47_RS04240	COG1477	protein flavinylation
FLM47_RS04245	COG2991	Protein conserved in bacteria
FLM47_RS04255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FLM47_RS04325	COG0123	including yeast histone deacetylase and acetoin utilization protein
FLM47_RS04335	COG0488	(ABC) transporter
FLM47_RS04350	COG0646	methionine synthase
FLM47_RS04350	COG1410	methionine synthase
FLM47_RS04355	COG1410	methionine synthase
FLM47_RS04355	COG0646	methionine synthase
FLM47_RS04380	COG1794	racemase activity, acting on amino acids and derivatives
FLM47_RS04390	COG3237	CsbD-like
FLM47_RS04415	COG1815	bacterial-type flagellum-dependent cell motility
FLM47_RS04420	COG1558	bacterial-type flagellum-dependent cell motility
FLM47_RS04425	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FLM47_RS04430	COG1749	Flagellar hook protein flgE
FLM47_RS04435	COG4787	bacterial-type flagellum-dependent cell motility
FLM47_RS04440	COG4786	Flagellar basal body rod
FLM47_RS04445	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FLM47_RS04450	COG1706	bacterial-type flagellum-dependent cell motility
FLM47_RS04475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLM47_RS04480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLM47_RS04485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLM47_RS04490	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FLM47_RS04515	COG1191	sigma factor activity
FLM47_RS04520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLM47_RS04525	COG1360	Flagellar Motor Protein
FLM47_RS04550	COG1987	bacterial-type flagellum assembly
FLM47_RS04570	COG2885	chlorophyll binding
FLM47_RS04580	COG1677	Flagellar hook-basal body complex protein FliE
FLM47_RS04590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLM47_RS04610	COG1643	Atp-dependent helicase
FLM47_RS04620	COG4191	Histidine kinase
FLM47_RS04620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM47_RS04635	COG1064	alcohol dehydrogenase
FLM47_RS04645	COG1476	TRANSCRIPTIONal
FLM47_RS04660	COG0583	DNA-binding transcription factor activity
FLM47_RS04680	COG2200	EAL domain
FLM47_RS04685	COG1764	response to oxidative stress
FLM47_RS04695	COG0415	Belongs to the DNA photolyase family
FLM47_RS04700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLM47_RS04710	COG0625	glutathione transferase activity
FLM47_RS04720	COG0693	protein deglycase activity
FLM47_RS04725	COG0583	DNA-binding transcription factor activity
FLM47_RS04745	COG0339	signal peptide processing
FLM47_RS04750	COG3264	Mechanosensitive ion channel
FLM47_RS04750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FLM47_RS04755	COG4771	TonB-dependent receptor
FLM47_RS04770	COG1793	dna ligase
FLM47_RS04775	COG0443	Heat shock 70 kDa protein
FLM47_RS04785	COG1280	lysine exporter protein (LysE YggA)
FLM47_RS04805	COG0739	heme binding
FLM47_RS04820	COG3104	oligopeptide transport
FLM47_RS04835	COG3047	cAMP biosynthetic process
FLM47_RS04840	COG0534	Mate efflux family protein
FLM47_RS04855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLM47_RS04870	COG2201	protein-glutamate methylesterase activity
FLM47_RS04880	COG0728	peptidoglycan biosynthetic process
FLM47_RS04885	COG0196	riboflavin kinase activity
FLM47_RS04900	COG1047	Peptidyl-prolyl cis-trans
FLM47_RS04910	COG2972	Histidine kinase
FLM47_RS04910	COG0745	RESPONSE REGULATOR receiver
FLM47_RS04960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLM47_RS04965	COG0564	pseudouridine synthase activity
FLM47_RS04975	COG0542	response to heat
FLM47_RS04980	COG0840	transmembrane signaling receptor activity
FLM47_RS04995	COG4536	flavin adenine dinucleotide binding
FLM47_RS05000	COG4137	Cytochrome C assembly protein
FLM47_RS05005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLM47_RS05030	COG4286	Uncharacterised protein family (UPF0160)
FLM47_RS05035	COG1605	Chorismate mutase
FLM47_RS05035	COG0287	Prephenate dehydrogenase
FLM47_RS05040	COG0077	Prephenate dehydratase
FLM47_RS05040	COG1605	Chorismate mutase
FLM47_RS05050	COG0023	Translation Initiation Factor
FLM47_RS05060	COG1448	Aminotransferase
FLM47_RS05070	COG1595	DNA-templated transcription, initiation
FLM47_RS05080	COG2304	oxidoreductase activity
FLM47_RS05100	COG0714	Associated with various cellular activities
FLM47_RS05115	COG2315	Protein conserved in bacteria
FLM47_RS05145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLM47_RS05180	COG1025	Belongs to the peptidase M16 family
FLM47_RS05185	COG2062	phosphohistidine phosphatase, SixA
FLM47_RS05195	COG2840	Smr protein MutS2
FLM47_RS05200	COG2890	protein-(glutamine-N5) methyltransferase activity
FLM47_RS05220	COG3101	peptidyl-lysine hydroxylation
FLM47_RS05235	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FLM47_RS05250	COG0071	Belongs to the small heat shock protein (HSP20) family
FLM47_RS05270	COG3046	protein related to deoxyribodipyrimidine photolyase
FLM47_RS05285	COG0195	Participates in both transcription termination and antitermination
FLM47_RS05325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLM47_RS05325	COG2111	Na H antiporter
FLM47_RS05330	COG1006	Multisubunit Na H antiporter MnhC subunit
FLM47_RS05335	COG0651	ATP synthesis coupled electron transport
FLM47_RS05345	COG2212	antiporter activity
FLM47_RS05360	COG0789	Transcriptional regulator
FLM47_RS05365	COG2217	Heavy metal translocating P-type atpase
FLM47_RS05400	COG0741	lytic transglycosylase activity
FLM47_RS05400	COG1388	LysM domain
FLM47_RS05410	COG2226	methyltransferase
FLM47_RS05465	COG3842	ATPase activity
FLM47_RS05480	COG1619	proteins homologs of microcin C7 resistance protein MccF
FLM47_RS05485	COG0121	glutamine amidotransferase
FLM47_RS05495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLM47_RS05520	COG1451	nucleotide metabolic process
FLM47_RS05525	COG1801	Protein of unknown function DUF72
FLM47_RS05560	COG0513	Belongs to the DEAD box helicase family
FLM47_RS05580	COG2816	NAD+ diphosphatase activity
FLM47_RS05585	COG0626	cystathionine gamma-synthase activity
FLM47_RS05620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLM47_RS05625	COG1823	symporter activity
FLM47_RS05630	COG2197	response regulator
FLM47_RS05685	COG1115	amino acid carrier protein
FLM47_RS05715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLM47_RS05740	COG2866	Carboxypeptidase
FLM47_RS05745	COG1115	amino acid carrier protein
FLM47_RS05755	COG3139	Protein of unknown function (DUF1315)
FLM47_RS05775	COG3604	Transcriptional regulator
FLM47_RS05805	COG5001	Diguanylate cyclase
FLM47_RS05805	COG3300	MHYT domain
FLM47_RS05815	COG1288	antiporter activity
FLM47_RS05840	COG0427	acetyl-CoA hydrolase
FLM47_RS05875	COG2201	protein-glutamate methylesterase activity
FLM47_RS05880	COG4251	negative regulation of phosphorylation
FLM47_RS05895	COG2755	lipolytic protein G-D-S-L family
FLM47_RS05900	COG4181	ATPase activity
FLM47_RS05905	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FLM47_RS05925	COG0811	peptide transport
FLM47_RS05945	COG2885	chlorophyll binding
FLM47_RS06010	COG1902	pentaerythritol trinitrate reductase activity
FLM47_RS06030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FLM47_RS06035	COG1074	ATP-dependent DNA helicase activity
FLM47_RS06040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLM47_RS06045	COG2860	membrane
FLM47_RS06070	COG0589	response to stress
FLM47_RS06080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLM47_RS06095	COG2217	Heavy metal translocating P-type atpase
FLM47_RS06105	COG2010	Cytochrome c
FLM47_RS06120	COG3278	Belongs to the heme-copper respiratory oxidase family
FLM47_RS06150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLM47_RS06155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLM47_RS06160	COG2957	Belongs to the agmatine deiminase family
FLM47_RS06190	COG2188	Transcriptional regulator
FLM47_RS06195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLM47_RS06235	COG3083	sulfuric ester hydrolase activity
FLM47_RS06245	COG3081	Nucleoid-associated protein
FLM47_RS06250	COG1530	ribonuclease E activity
FLM47_RS06260	COG0546	phosphoglycolate phosphatase activity
FLM47_RS06270	COG1399	metal-binding, possibly nucleic acid-binding protein
FLM47_RS06285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLM47_RS06295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLM47_RS06300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLM47_RS06305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLM47_RS06310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLM47_RS06320	COG0470	DNA polymerase III
FLM47_RS06330	COG0084	hydrolase, TatD family'
FLM47_RS06350	COG2203	Gaf domain
FLM47_RS06350	COG2199	diguanylate cyclase activity
FLM47_RS06350	COG2200	EAL domain
FLM47_RS06360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLM47_RS06365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLM47_RS06370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FLM47_RS06375	COG0438	transferase activity, transferring glycosyl groups
FLM47_RS06390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLM47_RS06400	COG0297	glycogen (starch) synthase activity
FLM47_RS06400	COG0438	transferase activity, transferring glycosyl groups
FLM47_RS06410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FLM47_RS06440	COG1596	polysaccharide export
FLM47_RS06445	COG0489	protein tyrosine kinase activity
FLM47_RS06445	COG3206	protein involved in exopolysaccharide biosynthesis
FLM47_RS06470	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLM47_RS06475	COG0372	Belongs to the citrate synthase family
FLM47_RS06480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLM47_RS06505	COG1943	Transposase
FLM47_RS06530	COG0307	riboflavin synthase, alpha
FLM47_RS06540	COG3001	Fructosamine kinase
FLM47_RS06560	COG1228	amidohydrolase
FLM47_RS06575	COG1278	Cold shock
FLM47_RS06580	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FLM47_RS06585	COG0542	response to heat
FLM47_RS06595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FLM47_RS06605	COG1049	propionate catabolic process, 2-methylcitrate cycle
FLM47_RS06610	COG0492	ferredoxin-NADP+ reductase activity
FLM47_RS06615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLM47_RS06620	COG0686	Belongs to the AlaDH PNT family
FLM47_RS06630	COG0531	amino acid
FLM47_RS06630	COG1674	ftsk spoiiie
FLM47_RS06640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLM47_RS06705	COG2133	pyrroloquinoline quinone binding
FLM47_RS06715	COG1914	H( )-stimulated, divalent metal cation uptake system
FLM47_RS06735	COG3291	Pkd domain containing protein
FLM47_RS06745	COG4932	domain protein
FLM47_RS06745	COG5492	domain, Protein
FLM47_RS06755	COG1132	(ABC) transporter
FLM47_RS06765	COG2234	aminopeptidase activity
FLM47_RS06800	COG1876	peptidase activity
FLM47_RS06810	COG1393	Belongs to the ArsC family
FLM47_RS06825	COG0280	phosphate acetyltransferase
FLM47_RS06825	COG0857	belongs to the CobB CobQ family
FLM47_RS06830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLM47_RS06835	COG3092	negative regulation of chromosome organization
FLM47_RS06840	COG2226	methyltransferase
FLM47_RS06865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLM47_RS06870	COG1187	pseudouridine synthase activity
FLM47_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
FLM47_RS06880	COG2267	carboxylic ester hydrolase activity
FLM47_RS06885	COG0616	signal peptide processing
FLM47_RS06890	COG1301	dicarboxylic acid transport
FLM47_RS06915	COG0366	Alpha amylase catalytic
FLM47_RS06960	COG3547	Transposase (IS116 IS110 IS902 family)
FLM47_RS07000	COG2860	membrane
FLM47_RS07010	COG0837	glucose binding
FLM47_RS07015	COG1609	Transcriptional regulator
FLM47_RS07045	COG3590	peptidase
FLM47_RS07050	COG5265	(ABC) transporter
FLM47_RS07060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLM47_RS07065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLM47_RS07080	COG2824	Alkylphosphonate utilization operon protein PhnA
FLM47_RS07085	COG0189	ligase activity
FLM47_RS07090	COG0456	acetyltransferase
FLM47_RS07090	COG1214	PFAM Peptidase M22, glycoprotease
FLM47_RS07100	COG3300	MHYT domain
FLM47_RS07100	COG5001	Diguanylate cyclase
FLM47_RS07135	COG0583	DNA-binding transcription factor activity
FLM47_RS07140	COG4591	ABC-type transport system involved in lipoprotein release permease component
FLM47_RS07150	COG4591	ABC-type transport system involved in lipoprotein release permease component
FLM47_RS07160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLM47_RS07170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLM47_RS07195	COG0739	heme binding
FLM47_RS07210	COG0318	PFAM AMP-dependent synthetase and ligase
FLM47_RS07245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLM47_RS07250	COG1522	sequence-specific DNA binding
FLM47_RS07255	COG0659	secondary active sulfate transmembrane transporter activity
FLM47_RS07260	COG3275	phosphorelay sensor kinase activity
FLM47_RS07265	COG3279	Response regulator of the LytR AlgR family
FLM47_RS07270	COG0469	pyruvate kinase activity
FLM47_RS07280	COG0252	asparaginase activity
FLM47_RS07285	COG0616	signal peptide processing
FLM47_RS07290	COG0446	pyridine nucleotide-disulphide oxidoreductase
FLM47_RS07290	COG1902	pentaerythritol trinitrate reductase activity
FLM47_RS07300	COG0778	Nitroreductase
FLM47_RS07320	COG0545	Peptidyl-prolyl cis-trans isomerase
FLM47_RS07345	COG3738	Protein conserved in bacteria
FLM47_RS07360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLM47_RS07390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLM47_RS07395	COG0539	negative regulation of cytoplasmic translation
FLM47_RS07410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FLM47_RS07430	COG0513	Belongs to the DEAD box helicase family
FLM47_RS07445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM47_RS07450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM47_RS07455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLM47_RS07455	COG0517	IMP dehydrogenase activity
FLM47_RS07460	COG2176	DNA-directed DNA polymerase activity
FLM47_RS07465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLM47_RS07470	COG0367	asparagine synthase
FLM47_RS07475	COG1984	allophanate hydrolase subunit 2
FLM47_RS07480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FLM47_RS07490	COG0583	DNA-binding transcription factor activity
FLM47_RS07500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLM47_RS07520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLM47_RS07525	COG1960	acyl-CoA dehydrogenase activity
FLM47_RS07535	COG0183	Belongs to the thiolase family
FLM47_RS07550	COG1024	Enoyl-CoA hydratase
FLM47_RS07555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FLM47_RS07565	COG1028	Short-chain dehydrogenase reductase Sdr
FLM47_RS07575	COG0515	serine threonine protein kinase
FLM47_RS07610	COG3038	cytochrome b561
FLM47_RS07620	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLM47_RS07635	COG4628	conserved protein (DUF2132)
FLM47_RS07640	COG0604	alcohol dehydrogenase
FLM47_RS07645	COG1309	transcriptional regulator
FLM47_RS07650	COG3130	regulation of translation
FLM47_RS07675	COG2056	Na+-H+ antiporter family
FLM47_RS07690	COG0714	Associated with various cellular activities
FLM47_RS07695	COG2201	protein-glutamate methylesterase activity
FLM47_RS07805	COG0205	6-phosphofructokinase activity
FLM47_RS07840	COG0281	malic enzyme
FLM47_RS07845	COG0405	Gamma-glutamyltransferase
FLM47_RS07865	COG2855	membrane
FLM47_RS07875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLM47_RS07880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLM47_RS07885	COG0488	(ABC) transporter
FLM47_RS07900	COG1309	transcriptional regulator
FLM47_RS07930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLM47_RS07940	COG0583	DNA-binding transcription factor activity
FLM47_RS07950	COG0183	Belongs to the thiolase family
FLM47_RS07965	COG1278	Cold shock
FLM47_RS08010	COG3547	Transposase (IS116 IS110 IS902 family)
FLM47_RS08035	COG0501	Belongs to the peptidase M48B family
FLM47_RS08050	COG2226	methyltransferase
FLM47_RS08080	COG1178	ABC-type Fe3 transport system permease component
FLM47_RS08085	COG3842	ATPase activity
FLM47_RS08135	COG1720	tRNA m6t6A37 methyltransferase activity
FLM47_RS08145	COG1668	transmembrane transport
FLM47_RS08150	COG4555	ABC transporter
FLM47_RS08175	COG0022	dehydrogenase e1 component
FLM47_RS08190	COG0033	Phosphoglucomutase
FLM47_RS08200	COG0596	Alpha beta hydrolase
FLM47_RS08220	COG0735	belongs to the Fur family
FLM47_RS08245	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLM47_RS08250	COG0567	Dehydrogenase, E1 component
FLM47_RS08260	COG1053	succinate dehydrogenase
FLM47_RS08265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FLM47_RS08280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLM47_RS08285	COG2166	iron-sulfur cluster assembly
FLM47_RS08290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FLM47_RS08295	COG0564	pseudouridine synthase activity
FLM47_RS08320	COG2333	competence protein COMEC
FLM47_RS08320	COG0658	competence protein
FLM47_RS08360	COG2902	Dehydrogenase
FLM47_RS08370	COG4447	cellulose binding
FLM47_RS08390	COG0308	aminopeptidase N
FLM47_RS08415	COG1956	GAF domain-containing protein
FLM47_RS08435	COG0670	Belongs to the BI1 family
FLM47_RS08445	COG2923	Belongs to the DsrF TusC family
FLM47_RS08455	COG2920	part of a sulfur-relay system
FLM47_RS08480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLM47_RS08485	COG2850	peptidyl-arginine hydroxylation
FLM47_RS08495	COG0436	Aminotransferase
FLM47_RS08520	COG0489	protein tyrosine kinase activity
FLM47_RS08600	COG4771	TonB-dependent receptor
FLM47_RS08630	COG3038	cytochrome b561
FLM47_RS08640	COG0009	L-threonylcarbamoyladenylate synthase
FLM47_RS08645	COG0613	PHP domain protein
FLM47_RS08650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLM47_RS08655	COG0512	Glutamine amidotransferase of anthranilate synthase
FLM47_RS08665	COG0135	phosphoribosylanthranilate isomerase activity
FLM47_RS08665	COG0134	indole-3-glycerol-phosphate synthase activity
FLM47_RS08680	COG0693	protein deglycase activity
FLM47_RS08685	COG0776	regulation of translation
FLM47_RS08695	COG0733	neurotransmitter:sodium symporter activity
FLM47_RS08700	COG2350	Protein conserved in bacteria
FLM47_RS08710	COG0745	RESPONSE REGULATOR receiver
FLM47_RS08715	COG2205	protein histidine kinase activity
FLM47_RS08740	COG0628	permease
FLM47_RS08745	COG1090	epimerase
FLM47_RS08765	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FLM47_RS08770	COG1505	serine-type exopeptidase activity
FLM47_RS08785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLM47_RS08795	COG0633	Ferredoxin
FLM47_RS08795	COG0543	2 iron, 2 sulfur cluster binding
FLM47_RS08800	COG2133	pyrroloquinoline quinone binding
FLM47_RS08820	COG0300	oxidoreductase activity
FLM47_RS08835	COG0583	DNA-binding transcription factor activity
FLM47_RS08845	COG0210	DNA helicase
FLM47_RS08850	COG0840	transmembrane signaling receptor activity
FLM47_RS08855	COG1741	Belongs to the pirin family
FLM47_RS08860	COG0435	Glutathione S-transferase
FLM47_RS08865	COG2259	Doxx family
FLM47_RS08870	COG0583	DNA-binding transcription factor activity
FLM47_RS08905	COG1404	Belongs to the peptidase S8 family
FLM47_RS08910	COG0596	Alpha beta hydrolase
FLM47_RS08930	COG2925	Exonuclease
FLM47_RS08935	COG2084	Dehydrogenase
FLM47_RS08940	COG0386	Belongs to the glutathione peroxidase family
FLM47_RS08945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLM47_RS08950	COG0733	neurotransmitter:sodium symporter activity
FLM47_RS08960	COG0527	aspartate kinase activity
FLM47_RS08965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLM47_RS09015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM47_RS09030	COG0583	DNA-binding transcription factor activity
FLM47_RS09050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLM47_RS09055	COG0505	Belongs to the CarA family
FLM47_RS09080	COG2814	Major facilitator Superfamily
FLM47_RS09090	COG1420	regulation of RNA biosynthetic process
FLM47_RS09105	COG0497	DNA recombination
FLM47_RS09115	COG0493	'glutamate synthase
FLM47_RS09120	COG0067	glutamate synthase
FLM47_RS09120	COG0069	glutamate synthase activity
FLM47_RS09120	COG0070	glutamate synthase
FLM47_RS09125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM47_RS09130	COG1136	(ABC) transporter
FLM47_RS09135	COG0577	efflux transmembrane transporter activity
FLM47_RS09135	COG1136	(ABC) transporter
FLM47_RS09140	COG1136	(ABC) transporter
FLM47_RS09140	COG0577	efflux transmembrane transporter activity
FLM47_RS09150	COG3852	Histidine kinase
FLM47_RS09155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FLM47_RS09165	COG2766	serine protein kinase
FLM47_RS09170	COG2718	Belongs to the UPF0229 family
FLM47_RS09175	COG2719	SpoVR family
FLM47_RS09185	COG3706	GGDEF domain
FLM47_RS09190	COG2201	protein-glutamate methylesterase activity
FLM47_RS09195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FLM47_RS09210	COG0564	pseudouridine synthase activity
FLM47_RS09240	COG3220	belongs to the UPF0276 family
FLM47_RS09250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLM47_RS09275	COG0848	biopolymer transport protein
FLM47_RS09280	COG0811	peptide transport
FLM47_RS09285	COG0811	peptide transport
FLM47_RS09295	COG1278	Cold shock
FLM47_RS09300	COG0418	dihydroorotase activity
FLM47_RS09305	COG5001	Diguanylate cyclase
FLM47_RS09305	COG3300	MHYT domain
FLM47_RS09310	COG0583	DNA-binding transcription factor activity
FLM47_RS09315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FLM47_RS09325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLM47_RS09335	COG1228	amidohydrolase
FLM47_RS09340	COG3228	Belongs to the MtfA family
FLM47_RS09350	COG3706	GGDEF domain
FLM47_RS09370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLM47_RS09380	COG1760	l-serine dehydratase
FLM47_RS09385	COG0583	DNA-binding transcription factor activity
FLM47_RS09395	COG2252	PERMEase
FLM47_RS09410	COG3012	SEC-C Motif Domain Protein
FLM47_RS09445	COG1418	mRNA catabolic process
FLM47_RS09465	COG1643	Atp-dependent helicase
FLM47_RS09495	COG0363	glucosamine-6-phosphate deaminase activity
FLM47_RS09500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLM47_RS09510	COG1104	cysteine desulfurase activity
FLM47_RS09530	COG4783	chaperone-mediated protein folding
FLM47_RS09535	COG1393	Belongs to the ArsC family
FLM47_RS09555	COG2854	intermembrane phospholipid transfer
FLM47_RS09560	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FLM47_RS09580	COG2716	regulation of RNA biosynthetic process
FLM47_RS09585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLM47_RS09605	COG2329	Antibiotic biosynthesis monooxygenase
FLM47_RS09615	COG0602	queuosine metabolic process
FLM47_RS09645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FLM47_RS09655	COG0534	Mate efflux family protein
FLM47_RS09680	COG2199	diguanylate cyclase activity
FLM47_RS09680	COG2200	EAL domain
FLM47_RS09680	COG2203	Gaf domain
FLM47_RS09690	COG2878	Part of a membrane complex involved in electron transport
FLM47_RS09700	COG4658	electron transport chain
FLM47_RS09705	COG4659	FMN binding
FLM47_RS09710	COG4660	Part of a membrane complex involved in electron transport
FLM47_RS09715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLM47_RS09730	COG0739	heme binding
FLM47_RS09775	COG2311	Membrane
FLM47_RS09780	COG1982	Orn Lys Arg decarboxylase major
FLM47_RS09790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLM47_RS09875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLM47_RS09905	COG1196	nuclear chromosome segregation
FLM47_RS09910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLM47_RS09915	COG4269	membrane
FLM47_RS09935	COG1166	arginine decarboxylase activity
FLM47_RS09945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLM47_RS09965	COG2363	Small membrane protein
FLM47_RS09975	COG0583	DNA-binding transcription factor activity
FLM47_RS10000	COG3437	response regulator, receiver
FLM47_RS10000	COG0784	Response regulator, receiver
FLM47_RS10005	COG2890	protein-(glutamine-N5) methyltransferase activity
FLM47_RS10045	COG0012	GTP binding
FLM47_RS10095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLM47_RS10105	COG1702	phosphate starvation-inducible protein PhoH
FLM47_RS10115	COG4535	Mg2 and Co2 transporter CorC
FLM47_RS10120	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FLM47_RS10160	COG0545	Peptidyl-prolyl cis-trans isomerase
FLM47_RS10165	COG1067	ATP-dependent peptidase activity
FLM47_RS10170	COG2888	peptidyl-tyrosine sulfation
FLM47_RS10180	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FLM47_RS10190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLM47_RS10195	COG0799	negative regulation of ribosome biogenesis
FLM47_RS10205	COG0768	penicillin binding
FLM47_RS10210	COG0772	Belongs to the SEDS family
FLM47_RS10215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLM47_RS10220	COG1686	Belongs to the peptidase S11 family
FLM47_RS10240	COG0724	RNA recognition motif
FLM47_RS10260	COG0564	pseudouridine synthase activity
FLM47_RS10265	COG3098	single-species biofilm formation
FLM47_RS10295	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FLM47_RS10315	COG2911	Protein conserved in bacteria
FLM47_RS10320	COG0729	surface antigen
FLM47_RS10330	COG1061	Type III restriction enzyme res subunit
FLM47_RS10335	COG4206	TonB-dependent receptor
FLM47_RS10340	COG0417	DNA replication proofreading
FLM47_RS10345	COG1199	ATP-dependent helicase activity
FLM47_RS10350	COG0730	response to heat
FLM47_RS10360	COG0123	including yeast histone deacetylase and acetoin utilization protein
FLM47_RS10375	COG2176	DNA-directed DNA polymerase activity
FLM47_RS10380	COG0477	Major facilitator Superfamily
FLM47_RS10385	COG0784	Response regulator, receiver
FLM47_RS10385	COG2205	protein histidine kinase activity
FLM47_RS10395	COG2197	response regulator
FLM47_RS10400	COG4585	Histidine kinase
FLM47_RS10430	COG0583	DNA-binding transcription factor activity
FLM47_RS10435	COG0431	NADPH-dependent FMN reductase
FLM47_RS10440	COG0783	Belongs to the Dps family
FLM47_RS10445	COG0435	Glutathione S-transferase
FLM47_RS10480	COG3706	GGDEF domain
FLM47_RS10490	COG0037	tRNA processing
FLM47_RS10500	COG0587	DNA-directed DNA polymerase activity
FLM47_RS10520	COG1294	oxidase, subunit
FLM47_RS10525	COG4890	Cyd operon protein YbgT
FLM47_RS10530	COG4988	ABC transporter
FLM47_RS10535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLM47_RS10540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLM47_RS10545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FLM47_RS10570	COG0750	zinc metalloprotease
FLM47_RS10575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FLM47_RS10585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLM47_RS10610	COG0024	Methionine aminopeptidase
FLM47_RS10640	COG0626	cystathionine gamma-synthase activity
FLM47_RS10645	COG3768	UPF0283 membrane protein
FLM47_RS10650	COG3106	COG3106 Predicted ATPase
FLM47_RS10655	COG1983	PspC domain protein
FLM47_RS10665	COG1842	Phage shock protein A
FLM47_RS10670	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FLM47_RS10675	COG0747	negative chemotaxis
FLM47_RS10695	COG4172	Belongs to the ABC transporter superfamily
FLM47_RS10700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLM47_RS10710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FLM47_RS10715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLM47_RS10760	COG0697	spore germination
FLM47_RS10770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLM47_RS10780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM47_RS10780	COG4191	Histidine kinase
FLM47_RS10800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLM47_RS10805	COG1286	toxin biosynthetic process
FLM47_RS10815	COG0285	dihydrofolate synthase activity
FLM47_RS10845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLM47_RS10855	COG0702	epimerase
FLM47_RS10880	COG2885	chlorophyll binding
FLM47_RS10885	COG0814	amino acid
FLM47_RS10910	COG2197	response regulator
FLM47_RS10935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLM47_RS10950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLM47_RS10955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLM47_RS10965	COG1534	Rna-binding protein
FLM47_RS10995	COG0745	RESPONSE REGULATOR receiver
FLM47_RS11000	COG2205	protein histidine kinase activity
FLM47_RS11005	COG0733	neurotransmitter:sodium symporter activity
FLM47_RS11010	COG2153	protein acetylation
FLM47_RS11015	COG4326	sporulation control protein
FLM47_RS11030	COG2205	protein histidine kinase activity
FLM47_RS11035	COG0745	RESPONSE REGULATOR receiver
FLM47_RS11050	COG3706	GGDEF domain
FLM47_RS11055	COG0583	DNA-binding transcription factor activity
FLM47_RS11070	COG0457	Tetratricopeptide repeat
FLM47_RS11085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLM47_RS11095	COG2867	negative regulation of translational initiation
FLM47_RS11105	COG4206	TonB-dependent receptor
FLM47_RS11110	COG0450	alkyl hydroperoxide reductase
FLM47_RS11130	COG1555	photosystem II stabilization
FLM47_RS11135	COG3141	response to X-ray
FLM47_RS11140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLM47_RS11145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FLM47_RS11160	COG3088	subunit of a heme lyase
FLM47_RS11160	COG4235	cytochrome complex assembly
FLM47_RS11170	COG1138	Cytochrome C-type biogenesis protein
FLM47_RS11180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLM47_RS11185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLM47_RS11190	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLM47_RS11195	COG4133	protoheme IX ABC transporter activity
FLM47_RS11215	COG0835	chemotaxis
FLM47_RS11225	COG1192	Involved in chromosome partitioning
FLM47_RS11230	COG1360	Flagellar Motor Protein
FLM47_RS11235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLM47_RS11245	COG0643	Histidine kinase
FLM47_RS11245	COG0784	Response regulator, receiver
FLM47_RS11245	COG2198	Histidine kinase
FLM47_RS11250	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FLM47_RS11275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLM47_RS11300	COG3190	flagellar
FLM47_RS11320	COG3144	bacterial-type flagellum assembly
FLM47_RS11340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLM47_RS11350	COG1677	Flagellar hook-basal body complex protein FliE
FLM47_RS11360	COG3852	Histidine kinase
FLM47_RS11365	COG0519	Catalyzes the synthesis of GMP from XMP
FLM47_RS11380	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FLM47_RS11390	COG0318	PFAM AMP-dependent synthetase and ligase
FLM47_RS11405	COG4310	Domain of unknown function (DUF2172)
FLM47_RS11415	COG1516	flagellar protein fliS
FLM47_RS11425	COG1086	Polysaccharide biosynthesis protein
FLM47_RS11430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLM47_RS11435	COG0667	Aldo Keto reductase
FLM47_RS11440	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FLM47_RS11445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLM47_RS11450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLM47_RS11465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLM47_RS11470	COG2089	acid synthase
FLM47_RS11490	COG1334	flagellar protein FlaG
FLM47_RS11515	COG1705	Flagellar rod assembly protein muramidase FlgJ
FLM47_RS11515	COG3951	Flagellar rod assembly protein muramidase FlgJ
FLM47_RS11530	COG4786	Flagellar basal body rod
FLM47_RS11535	COG4786	Flagellar basal body rod
FLM47_RS11555	COG1815	bacterial-type flagellum-dependent cell motility
FLM47_RS11560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FLM47_RS11565	COG0784	Response regulator, receiver
FLM47_RS11565	COG0835	chemotaxis
FLM47_RS11600	COG0678	peroxiredoxin activity
FLM47_RS11600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLM47_RS11615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FLM47_RS11675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLM47_RS11690	COG0730	response to heat
FLM47_RS11695	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FLM47_RS11705	COG3066	DNA modification
FLM47_RS11720	COG3956	TIGRFAM MazG family protein
FLM47_RS11725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLM47_RS11735	COG2205	protein histidine kinase activity
FLM47_RS11735	COG3437	response regulator, receiver
FLM47_RS11735	COG3850	Histidine kinase
FLM47_RS11735	COG4999	Histidine kinase
FLM47_RS11775	COG3026	antisigma factor binding
FLM47_RS11785	COG1595	DNA-templated transcription, initiation
FLM47_RS11790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLM47_RS11800	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FLM47_RS11805	COG0354	folic acid binding
FLM47_RS11810	COG1047	Peptidyl-prolyl cis-trans
FLM47_RS11830	COG1024	Enoyl-CoA hydratase
FLM47_RS11830	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLM47_RS11840	COG1346	cytolysis
FLM47_RS11845	COG0668	transmembrane transport
FLM47_RS11850	COG4249	Peptidase C14 caspase catalytic subunit p20
FLM47_RS11850	COG2319	Wd-40 repeat
FLM47_RS11870	COG2203	Gaf domain
FLM47_RS11870	COG3706	GGDEF domain
FLM47_RS11870	COG4251	negative regulation of phosphorylation
FLM47_RS11870	COG5001	Diguanylate cyclase
FLM47_RS11875	COG2239	Acts as a magnesium transporter
FLM47_RS11885	COG0788	formyltetrahydrofolate deformylase activity
FLM47_RS11890	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FLM47_RS11910	COG4773	Receptor
FLM47_RS12025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLM47_RS12040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLM47_RS12045	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FLM47_RS12050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLM47_RS12055	COG3706	GGDEF domain
FLM47_RS12075	COG0560	Phosphoserine phosphatase
FLM47_RS12085	COG0084	hydrolase, TatD family'
FLM47_RS12105	COG5002	protein histidine kinase activity
FLM47_RS12105	COG0784	Response regulator, receiver
FLM47_RS12105	COG2198	Histidine kinase
FLM47_RS12110	COG0456	acetyltransferase
FLM47_RS12130	COG0517	IMP dehydrogenase activity
FLM47_RS12130	COG0516	GMP reductase activity
FLM47_RS12145	COG1045	serine acetyltransferase
FLM47_RS12150	COG0612	Peptidase, M16
FLM47_RS12170	COG2199	diguanylate cyclase activity
FLM47_RS12170	COG2203	Gaf domain
FLM47_RS12175	COG0513	Belongs to the DEAD box helicase family
FLM47_RS12210	COG0697	spore germination
FLM47_RS12230	COG0745	RESPONSE REGULATOR receiver
FLM47_RS12235	COG0642	Histidine kinase
FLM47_RS12245	COG0617	tRNA 3'-terminal CCA addition
FLM47_RS12255	COG0741	lytic transglycosylase activity
FLM47_RS12265	COG2204	response regulator
FLM47_RS12275	COG2205	protein histidine kinase activity
FLM47_RS12335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLM47_RS12345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLM47_RS12370	COG5002	protein histidine kinase activity
FLM47_RS12410	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLM47_RS12420	COG0784	Response regulator, receiver
FLM47_RS12420	COG2198	Histidine kinase
FLM47_RS12420	COG5002	protein histidine kinase activity
FLM47_RS12430	COG3706	GGDEF domain
FLM47_RS12465	COG1979	alcohol dehydrogenase
FLM47_RS12470	COG2207	Transcriptional regulator
FLM47_RS12475	COG3706	GGDEF domain
FLM47_RS12495	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FLM47_RS12530	COG0668	transmembrane transport
FLM47_RS12540	COG1902	pentaerythritol trinitrate reductase activity
FLM47_RS12560	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FLM47_RS12565	COG0477	Major facilitator Superfamily
FLM47_RS12575	COG0517	IMP dehydrogenase activity
FLM47_RS12575	COG1125	glycine betaine transport
FLM47_RS12585	COG0783	Belongs to the Dps family
FLM47_RS12615	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FLM47_RS12635	COG1757	Na H antiporter
FLM47_RS12640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLM47_RS12645	COG3876	Protein conserved in bacteria
FLM47_RS12675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FLM47_RS12685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FLM47_RS12690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLM47_RS12700	COG0716	FMN binding
FLM47_RS12720	COG0513	Belongs to the DEAD box helicase family
FLM47_RS12730	COG0668	transmembrane transport
FLM47_RS12740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLM47_RS12755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLM47_RS12760	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FLM47_RS12770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM47_RS12775	COG1120	ATPase activity
FLM47_RS12785	COG0583	DNA-binding transcription factor activity
FLM47_RS12790	COG3085	chromosome segregation
FLM47_RS12800	COG2962	Rard protein
FLM47_RS12805	COG2050	protein possibly involved in aromatic compounds catabolism
FLM47_RS12810	COG0514	ATP-dependent DNA helicase (RecQ)
FLM47_RS12840	COG4067	protein conserved in archaea
FLM47_RS12840	COG0189	ligase activity
FLM47_RS12855	COG0204	Acyl-transferase
FLM47_RS12875	COG3150	esterase
FLM47_RS12885	COG3151	Protein conserved in bacteria
FLM47_RS12890	COG0494	nUDIX hydrolase
FLM47_RS12895	COG1538	Outer membrane efflux protein
FLM47_RS12900	COG1560	Kdo2-lipid A biosynthetic process
FLM47_RS12910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FLM47_RS12925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FLM47_RS12930	COG0189	ligase activity
FLM47_RS12955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLM47_RS12960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLM47_RS12965	COG0762	integral membrane protein
FLM47_RS12975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLM47_RS12980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLM47_RS13000	COG1042	CoA-binding domain protein
FLM47_RS13000	COG0045	succinate-CoA ligase (ADP-forming) activity
FLM47_RS13000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLM47_RS13005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLM47_RS13030	COG3313	Fe-S protein
FLM47_RS13040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLM47_RS13060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FLM47_RS13065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLM47_RS13070	COG0564	pseudouridine synthase activity
FLM47_RS13080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FLM47_RS13115	COG2967	ApaG domain
FLM47_RS13120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FLM47_RS13125	COG0840	transmembrane signaling receptor activity
FLM47_RS13135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FLM47_RS13145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLM47_RS13155	COG0823	Involved in the tonB-independent uptake of proteins
FLM47_RS13155	COG1506	peptidase
FLM47_RS13155	COG4946	Tricorn protease homolog
FLM47_RS13220	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLM47_RS13240	COG2081	HI0933 family
FLM47_RS13245	COG1404	Belongs to the peptidase S8 family
FLM47_RS13250	COG0678	peroxiredoxin activity
FLM47_RS13285	COG0142	geranyltranstransferase activity
FLM47_RS13295	COG1438	arginine binding
FLM47_RS13305	COG3842	ATPase activity
FLM47_RS13315	COG1840	ABC-type Fe3 transport system, periplasmic component
FLM47_RS13325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLM47_RS13330	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLM47_RS13335	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FLM47_RS13340	COG2186	Transcriptional regulator
FLM47_RS13360	COG4969	Belongs to the N-Me-Phe pilin family
FLM47_RS13380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLM47_RS13395	COG0745	RESPONSE REGULATOR receiver
FLM47_RS13400	COG2205	protein histidine kinase activity
FLM47_RS13405	COG2267	carboxylic ester hydrolase activity
FLM47_RS13415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FLM47_RS13430	COG0840	transmembrane signaling receptor activity
FLM47_RS13445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FLM47_RS13450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLM47_RS13465	COG4942	peptidase
FLM47_RS13470	COG0793	Belongs to the peptidase S41A family
FLM47_RS13490	COG2177	Part of the ABC transporter FtsEX involved in
FLM47_RS13495	COG2884	Cell division ATP-binding protein ftsE
FLM47_RS13500	COG0552	protein localization to endoplasmic reticulum
FLM47_RS13505	COG0742	ribosomal rna small subunit methyltransferase
FLM47_RS13535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLM47_RS13540	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FLM47_RS13555	COG0151	Belongs to the GarS family
FLM47_RS13560	COG3300	MHYT domain
FLM47_RS13560	COG5001	Diguanylate cyclase
FLM47_RS13580	COG0123	including yeast histone deacetylase and acetoin utilization protein
FLM47_RS13595	COG1280	lysine exporter protein (LysE YggA)
FLM47_RS13615	COG0823	Involved in the tonB-independent uptake of proteins
FLM47_RS13640	COG2823	Periplasmic or secreted lipoprotein
FLM47_RS13665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLM47_RS13670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLM47_RS13675	COG1862	Preprotein translocase
FLM47_RS13690	COG5002	protein histidine kinase activity
FLM47_RS13690	COG5001	Diguanylate cyclase
FLM47_RS13700	COG0583	DNA-binding transcription factor activity
FLM47_RS13705	COG0306	phosphate transporter
FLM47_RS13710	COG1392	Phosphate transport regulator
FLM47_RS13715	COG0704	Plays a role in the regulation of phosphate uptake
FLM47_RS13725	COG0573	inorganic phosphate transmembrane transporter activity
FLM47_RS13745	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM47_RS13770	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FLM47_RS13775	COG2824	Alkylphosphonate utilization operon protein PhnA
FLM47_RS13785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FLM47_RS13795	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FLM47_RS13805	COG0741	lytic transglycosylase activity
FLM47_RS13805	COG1388	LysM domain
FLM47_RS13820	COG3618	amidohydrolase
FLM47_RS13875	COG4948	Mandelate Racemase Muconate Lactonizing
FLM47_RS13900	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
FLM47_RS13930	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FLM47_RS13940	COG0330	HflC and HflK could
FLM47_RS13945	COG0330	HflC and HflK could
FLM47_RS13950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLM47_RS13970	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLM47_RS13975	COG0802	atpase or kinase
FLM47_RS13980	COG0439	Biotin carboxylase
FLM47_RS13985	COG0511	ligase activity, forming carbon-carbon bonds
FLM47_RS13995	COG4232	protein-disulfide reductase activity
FLM47_RS14000	COG1324	tolerance protein
FLM47_RS14020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLM47_RS14025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FLM47_RS14025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FLM47_RS14055	COG0724	RNA recognition motif
FLM47_RS14060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FLM47_RS14075	COG1683	Conserved Protein
FLM47_RS14080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLM47_RS14085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLM47_RS14090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLM47_RS14095	COG0348	domain, Protein
FLM47_RS14140	COG2165	general secretion pathway protein
FLM47_RS14150	COG2165	general secretion pathway protein
FLM47_RS14155	COG1459	type II secretion system
FLM47_RS14160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLM47_RS14170	COG3031	protein transport across the cell outer membrane
FLM47_RS14215	COG1561	YicC-like family, N-terminal region
FLM47_RS14220	COG0784	Response regulator, receiver
FLM47_RS14220	COG2205	protein histidine kinase activity
FLM47_RS14235	COG0438	transferase activity, transferring glycosyl groups
FLM47_RS14240	COG2204	response regulator
FLM47_RS14270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLM47_RS14290	COG0110	maltose O-acetyltransferase activity
FLM47_RS14305	COG0438	transferase activity, transferring glycosyl groups
FLM47_RS14310	COG1215	transferase activity, transferring glycosyl groups
FLM47_RS14340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLM47_RS14360	COG1522	sequence-specific DNA binding
FLM47_RS14365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLM47_RS14370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLM47_RS14415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLM47_RS14420	COG0201	protein transport
FLM47_RS14505	COG0640	Transcriptional regulator
FLM47_RS14545	COG1132	(ABC) transporter
FLM47_RS14555	COG2885	chlorophyll binding
FLM47_RS14565	COG0668	transmembrane transport
FLM47_RS14570	COG0204	Acyl-transferase
FLM47_RS14575	COG0204	Acyl-transferase
FLM47_RS14580	COG1166	arginine decarboxylase activity
FLM47_RS14585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FLM47_RS14600	COG1082	Xylose isomerase domain protein TIM barrel
FLM47_RS14610	COG0745	RESPONSE REGULATOR receiver
FLM47_RS14615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLM47_RS14630	COG2183	response to ionizing radiation
FLM47_RS14645	COG0596	Alpha beta hydrolase
FLM47_RS14650	COG1040	competence protein
FLM47_RS14670	COG0534	Mate efflux family protein
FLM47_RS14675	COG0726	polysaccharide deacetylase
FLM47_RS14680	COG2201	protein-glutamate methylesterase activity
FLM47_RS14685	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FLM47_RS14690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FLM47_RS14700	COG0835	chemotaxis
FLM47_RS14705	COG0643	Histidine kinase
FLM47_RS14705	COG2198	Histidine kinase
FLM47_RS14710	COG0745	RESPONSE REGULATOR receiver
FLM47_RS14760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLM47_RS14775	COG3291	Pkd domain containing protein
FLM47_RS14800	COG1017	nitric oxide dioxygenase activity
FLM47_RS14800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM47_RS14810	COG3604	Transcriptional regulator
FLM47_RS14820	COG0431	NADPH-dependent FMN reductase
FLM47_RS14865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLM47_RS14880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLM47_RS14890	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FLM47_RS14895	COG0545	Peptidyl-prolyl cis-trans isomerase
FLM47_RS14910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FLM47_RS14915	COG0488	(ABC) transporter
FLM47_RS14925	COG1476	TRANSCRIPTIONal
FLM47_RS14935	COG0429	hydrolase of the alpha beta-hydrolase fold
FLM47_RS14940	COG3089	Belongs to the UPF0270 family
FLM47_RS15005	COG0537	adenosine 5'-monophosphoramidase activity
FLM47_RS15035	COG0069	glutamate synthase activity
FLM47_RS15070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLM47_RS15075	COG0805	protein transport
FLM47_RS15090	COG2203	Gaf domain
FLM47_RS15090	COG3706	GGDEF domain
FLM47_RS15090	COG4251	negative regulation of phosphorylation
FLM47_RS15090	COG5001	Diguanylate cyclase
FLM47_RS15100	COG3227	Zinc metalloprotease (Elastase)
FLM47_RS15115	COG4681	YaeQ
FLM47_RS15130	COG0783	Belongs to the Dps family
FLM47_RS15135	COG1770	oligopeptidase
FLM47_RS15140	COG3397	chitin binding
FLM47_RS15185	COG3428	Bacterial PH domain
FLM47_RS15195	COG0676	glucose-6-phosphate 1-epimerase activity
FLM47_RS15205	COG2832	Protein of unknown function (DUF454)
FLM47_RS15245	COG1136	(ABC) transporter
FLM47_RS15250	COG4447	cellulose binding
FLM47_RS15250	COG3291	Pkd domain containing protein
FLM47_RS15250	COG5520	Belongs to the glycosyl hydrolase 30 family
FLM47_RS15265	COG1785	Belongs to the alkaline phosphatase family
FLM47_RS15270	COG1785	Belongs to the alkaline phosphatase family
FLM47_RS15305	COG4946	Tricorn protease homolog
FLM47_RS15305	COG0793	Belongs to the peptidase S41A family
FLM47_RS15310	COG0513	Belongs to the DEAD box helicase family
FLM47_RS15400	COG3177	Filamentation induced by cAMP protein fic
FLM47_RS15405	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FLM47_RS15410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLM47_RS15415	COG1349	DNA-binding transcription factor activity
FLM47_RS15420	COG0110	maltose O-acetyltransferase activity
FLM47_RS15435	COG0577	efflux transmembrane transporter activity
FLM47_RS15440	COG1136	(ABC) transporter
FLM47_RS15455	COG4191	Histidine kinase
FLM47_RS15545	COG1475	DNA binding
FLM47_RS15550	COG1192	Involved in chromosome partitioning
FLM47_RS15565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FLM47_RS15635	COG1280	lysine exporter protein (LysE YggA)
FLM47_RS15660	COG0823	Involved in the tonB-independent uptake of proteins
FLM47_RS15660	COG1506	peptidase
FLM47_RS15660	COG4946	Tricorn protease homolog
FLM47_RS15665	COG0564	pseudouridine synthase activity
FLM47_RS15690	COG4134	Bacterial extracellular solute-binding protein
FLM47_RS15700	COG4136	ATPase activity
FLM47_RS15705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLM47_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
FLM47_RS15785	COG3938	Belongs to the proline racemase family
FLM47_RS15810	COG3291	Pkd domain containing protein
FLM47_RS15815	COG1609	Transcriptional regulator
FLM47_RS15825	COG2814	Major facilitator Superfamily
FLM47_RS15835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLM47_RS15850	COG0625	glutathione transferase activity
FLM47_RS15860	COG1966	Carbon starvation protein
FLM47_RS15865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FLM47_RS15950	COG0789	Transcriptional regulator
FLM47_RS16055	COG3501	Rhs element vgr protein
FLM47_RS16125	COG1360	Flagellar Motor Protein
FLM47_RS16170	COG1309	transcriptional regulator
FLM47_RS16175	COG0840	transmembrane signaling receptor activity
FLM47_RS16180	COG1764	response to oxidative stress
FLM47_RS16185	COG1846	Transcriptional regulator
FLM47_RS16200	COG5001	Diguanylate cyclase
FLM47_RS16200	COG3300	MHYT domain
FLM47_RS16205	COG0745	RESPONSE REGULATOR receiver
FLM47_RS16220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FLM47_RS16225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FLM47_RS16270	COG2976	Protein conserved in bacteria
FLM47_RS16275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FLM47_RS16305	COG0415	Belongs to the DNA photolyase family
FLM47_RS16320	COG0583	DNA-binding transcription factor activity
FLM47_RS16325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLM47_RS16330	COG3002	Belongs to the UPF0753 family
FLM47_RS16340	COG0009	L-threonylcarbamoyladenylate synthase
FLM47_RS16345	COG5001	Diguanylate cyclase
FLM47_RS16345	COG1716	ATPase activity
FLM47_RS16365	COG2130	NADP-dependent
FLM47_RS16375	COG0784	Response regulator, receiver
FLM47_RS16375	COG3437	response regulator, receiver
FLM47_RS16380	COG4191	Histidine kinase
FLM47_RS16380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLM47_RS16385	COG0745	RESPONSE REGULATOR receiver
FLM47_RS16390	COG2205	protein histidine kinase activity
FLM47_RS16395	COG0569	domain protein
FLM47_RS16400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLM47_RS16420	COG0514	ATP-dependent DNA helicase (RecQ)
FLM47_RS16425	COG1252	NADH dehydrogenase
FLM47_RS16440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLM47_RS16445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLM47_RS16450	COG2971	BadF BadG BcrA BcrD
FLM47_RS16460	COG1609	Transcriptional regulator
FLM47_RS16465	COG0531	amino acid
FLM47_RS16470	COG4302	ethanolamine ammonia-lyase activity
FLM47_RS16475	COG4303	Ethanolamine ammonia lyase large subunit
FLM47_RS16485	COG3036	rescue of stalled ribosome
FLM47_RS16495	COG0745	RESPONSE REGULATOR receiver
FLM47_RS16500	COG3300	MHYT domain
FLM47_RS16500	COG5001	Diguanylate cyclase
FLM47_RS16510	COG4191	Histidine kinase
FLM47_RS16515	COG2204	response regulator
FLM47_RS16520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FLM47_RS16525	COG3135	benzoate transporter
FLM47_RS16610	COG1061	Type III restriction enzyme res subunit
FLM47_RS16645	COG0488	(ABC) transporter
FLM47_RS16650	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FLM47_RS16670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLM47_RS16685	COG0572	uridine kinase
FLM47_RS16690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLM47_RS16700	COG1278	Cold shock
FLM47_RS16720	COG0642	Histidine kinase
FLM47_RS16725	COG0745	RESPONSE REGULATOR receiver
FLM47_RS16765	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FLM47_RS16780	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FLM47_RS16810	COG0420	3'-5' exonuclease activity
FLM47_RS16825	COG1278	Cold shock
FLM47_RS16850	COG3040	lipid binding
FLM47_RS16900	COG1566	PFAM secretion protein HlyD family protein
FLM47_RS16905	COG1846	Transcriptional regulator
FLM47_RS16930	COG4771	TonB-dependent receptor
FLM47_RS16935	COG4558	Periplasmic binding protein
FLM47_RS16940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLM47_RS16945	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FLM47_RS16980	COG0583	DNA-binding transcription factor activity
FLM47_RS16995	COG4264	IucA IucC family
FLM47_RS17005	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FLM47_RS17010	COG0076	glutamate decarboxylase activity
FLM47_RS17060	COG0730	response to heat
FLM47_RS17105	COG3384	dioxygenase
FLM47_RS17110	COG0500	methyltransferase
FLM47_RS17120	COG0583	DNA-binding transcription factor activity
FLM47_RS17135	COG1322	Protein conserved in bacteria
FLM47_RS17140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLM47_RS17150	COG1192	Involved in chromosome partitioning
FLM47_RS17165	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FLM47_RS17175	COG0574	Belongs to the PEP-utilizing enzyme family
FLM47_RS17175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLM47_RS17185	COG0277	FAD linked oxidase domain protein
FLM47_RS17185	COG0247	lactate metabolic process
FLM47_RS17200	COG3263	regulation of cellular component size
FLM47_RS17220	COG1115	amino acid carrier protein
FLM47_RS17230	COG2423	ornithine cyclodeaminase activity
FLM47_RS17240	COG2169	Transcriptional regulator
FLM47_RS17250	COG4667	esterase of the alpha-beta hydrolase superfamily
FLM47_RS17255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLM47_RS17270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLM47_RS17275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLM47_RS17290	COG4895	conserved protein (DUF2196)
FLM47_RS17310	COG0840	transmembrane signaling receptor activity
FLM47_RS17345	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FLM47_RS17350	COG0848	biopolymer transport protein
FLM47_RS17355	COG0811	peptide transport
FLM47_RS17360	COG0811	peptide transport
FLM47_RS17390	COG2983	Belongs to the UPF0260 family
FLM47_RS17400	COG0402	S-adenosylhomocysteine deaminase activity
FLM47_RS17420	COG2951	lytic endotransglycosylase activity
FLM47_RS17435	COG2894	cell division
FLM47_RS17450	COG0318	PFAM AMP-dependent synthetase and ligase
FLM47_RS17460	COG1785	Belongs to the alkaline phosphatase family
FLM47_RS17475	COG1199	ATP-dependent helicase activity
FLM47_RS17505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FLM47_RS17515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLM47_RS17520	COG0131	Imidazoleglycerol-phosphate dehydratase
FLM47_RS17520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FLM47_RS17525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLM47_RS17540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLM47_RS17540	COG0140	phosphoribosyl-ATP diphosphatase activity
FLM47_RS17550	COG0753	catalase activity
FLM47_RS17560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLM47_RS17590	COG2873	o-acetylhomoserine
FLM47_RS17655	COG3706	GGDEF domain
FLM47_RS17660	COG1611	Belongs to the LOG family
FLM47_RS17680	COG0473	3-isopropylmalate dehydrogenase activity
FLM47_RS17685	COG0028	Belongs to the TPP enzyme family
FLM47_RS17690	COG0440	acetolactate synthase activity
FLM47_RS17715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FLM47_RS17740	COG0415	Belongs to the DNA photolyase family
FLM47_RS17755	COG1595	DNA-templated transcription, initiation
FLM47_RS17770	COG1272	protein, Hemolysin III
FLM47_RS17785	COG0583	DNA-binding transcription factor activity
FLM47_RS17800	COG1187	pseudouridine synthase activity
FLM47_RS17805	COG2311	Membrane
FLM47_RS17810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FLM47_RS17815	COG0297	glycogen (starch) synthase activity
FLM47_RS17825	COG0058	SHG alpha-glucan phosphorylase activity
FLM47_RS17835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLM47_RS17840	COG1640	4-alpha-glucanotransferase
FLM47_RS17855	COG3706	GGDEF domain
FLM47_RS17865	COG1522	sequence-specific DNA binding
FLM47_RS17870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLM47_RS17875	COG3138	arginine N-succinyltransferase
FLM47_RS17905	COG1309	transcriptional regulator
FLM47_RS17910	COG1012	belongs to the aldehyde dehydrogenase family
FLM47_RS17935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FLM47_RS17940	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FLM47_RS17945	COG0513	Belongs to the DEAD box helicase family
FLM47_RS17960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLM47_RS17990	COG0656	L-ascorbic acid biosynthetic process
FLM47_RS17995	COG2814	Major facilitator Superfamily
FLM47_RS18000	COG0583	DNA-binding transcription factor activity
FLM47_RS18015	COG0254	rRNA binding
FLM47_RS18040	COG0366	Alpha amylase catalytic
FLM47_RS18045	COG1215	transferase activity, transferring glycosyl groups
FLM47_RS18050	COG3769	mannosylglycerate metabolic process
FLM47_RS18125	COG1063	alcohol dehydrogenase
FLM47_RS18140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLM47_RS18170	COG0471	metal ion transport
FLM47_RS18180	COG2204	response regulator
FLM47_RS18185	COG4191	Histidine kinase
FLM47_RS18200	COG2205	protein histidine kinase activity
FLM47_RS18200	COG0784	Response regulator, receiver
FLM47_RS18230	COG2995	paraquat-inducible protein a
FLM47_RS18235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FLM47_RS18235	COG3008	intermembrane lipid transfer
FLM47_RS18250	COG1025	Belongs to the peptidase M16 family
FLM47_RS18260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLM47_RS18300	COG0456	acetyltransferase
FLM47_RS18300	COG1846	Transcriptional regulator
FLM47_RS18305	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FLM47_RS18310	COG0625	glutathione transferase activity
FLM47_RS18325	COG4628	conserved protein (DUF2132)
FLM47_RS18330	COG1803	Methylglyoxal synthase
FLM47_RS18330	COG1597	lipid kinase activity
FLM47_RS18355	COG1253	flavin adenine dinucleotide binding
FLM47_RS18365	COG0010	Belongs to the arginase family
FLM47_RS18370	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FLM47_RS18425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLM47_RS18435	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FLM47_RS18450	COG0346	lactoylglutathione lyase activity
FLM47_RS18455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLM47_RS18475	COG0457	Tetratricopeptide repeat
FLM47_RS18490	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FLM47_RS18515	COG1230	cation diffusion facilitator family transporter
FLM47_RS18525	COG2193	ferroxidase activity
FLM47_RS18535	COG2906	2 iron, 2 sulfur cluster binding
FLM47_RS18540	COG2249	NAD(P)H dehydrogenase (quinone) activity
FLM47_RS18555	COG3321	synthase
FLM47_RS18555	COG0604	alcohol dehydrogenase
FLM47_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
FLM47_RS18560	COG0583	DNA-binding transcription factor activity
FLM47_RS18575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLM47_RS18585	COG0798	PFAM Bile acid sodium symporter
FLM47_RS18590	COG0640	Transcriptional regulator
FLM47_RS18605	COG2119	membrane
FLM47_RS18615	COG0840	transmembrane signaling receptor activity
FLM47_RS18635	COG2203	Gaf domain
FLM47_RS18635	COG3706	GGDEF domain
FLM47_RS18635	COG5001	Diguanylate cyclase
FLM47_RS18635	COG4251	negative regulation of phosphorylation
FLM47_RS18640	COG4667	esterase of the alpha-beta hydrolase superfamily
FLM47_RS18645	COG2205	protein histidine kinase activity
FLM47_RS18645	COG0784	Response regulator, receiver
FLM47_RS18655	COG3634	alkyl hydroperoxide reductase activity
FLM47_RS18670	COG5002	protein histidine kinase activity
FLM47_RS18670	COG2205	protein histidine kinase activity
FLM47_RS18670	COG0784	Response regulator, receiver
FLM47_RS18675	COG0784	Response regulator, receiver
FLM47_RS18675	COG2205	protein histidine kinase activity
FLM47_RS18710	COG0673	inositol 2-dehydrogenase activity
FLM47_RS18720	COG4771	TonB-dependent receptor
FLM47_RS18725	COG0457	Tetratricopeptide repeat
FLM47_RS18735	COG0745	RESPONSE REGULATOR receiver
FLM47_RS18740	COG3850	Histidine kinase
FLM47_RS18740	COG5002	protein histidine kinase activity