locus-tag	class	description
PTUN_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PTUN_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PTUN_RS00025	COG0752	glycyl-tRNA synthetase alpha subunit
PTUN_RS00030	COG0751	glycine-tRNA ligase activity
PTUN_RS00040	COG0425	Belongs to the sulfur carrier protein TusA family
PTUN_RS00050	COG4191	Histidine kinase
PTUN_RS00055	COG0183	Belongs to the thiolase family
PTUN_RS00060	COG1024	Enoyl-CoA hydratase
PTUN_RS00060	COG1250	3-hydroxyacyl-CoA dehydrogenase
PTUN_RS00065	COG0741	lytic transglycosylase activity
PTUN_RS00070	COG0006	proline dipeptidase activity
PTUN_RS00075	COG1739	Uncharacterized protein family UPF0029
PTUN_RS00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PTUN_RS00085	COG0569	domain protein
PTUN_RS00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PTUN_RS00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PTUN_RS00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PTUN_RS00100	COG0242	peptide deformylase activity
PTUN_RS00110	COG0758	DNA mediated transformation
PTUN_RS00115	COG2922	Belongs to the Smg family
PTUN_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
PTUN_RS00130	COG0408	coproporphyrinogen oxidase activity
PTUN_RS00140	COG2346	COG2346, Truncated hemoglobins
PTUN_RS00145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PTUN_RS00155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PTUN_RS00200	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PTUN_RS00225	COG0429	hydrolase of the alpha beta-hydrolase fold
PTUN_RS00235	COG0488	(ABC) transporter
PTUN_RS00240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PTUN_RS00245	COG2900	Belongs to the SlyX family
PTUN_RS00255	COG0545	Peptidyl-prolyl cis-trans isomerase
PTUN_RS00260	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PTUN_RS00265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PTUN_RS00275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PTUN_RS00290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PTUN_RS00300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PTUN_RS00305	COG0724	RNA recognition motif
PTUN_RS00350	COG1444	tRNA N-acetyltransferase activity
PTUN_RS00355	COG0210	DNA helicase
PTUN_RS00360	COG0835	chemotaxis
PTUN_RS00360	COG0784	Response regulator, receiver
PTUN_RS00365	COG1011	Hydrolase
PTUN_RS00370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PTUN_RS00380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PTUN_RS00385	COG0019	diaminopimelate decarboxylase activity
PTUN_RS00395	COG1965	Belongs to the frataxin family
PTUN_RS00410	COG0181	hydroxymethylbilane synthase activity
PTUN_RS00415	COG2959	enzyme of heme biosynthesis
PTUN_RS00425	COG2205	protein histidine kinase activity
PTUN_RS00425	COG0784	Response regulator, receiver
PTUN_RS00430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PTUN_RS00445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PTUN_RS00460	COG0517	IMP dehydrogenase activity
PTUN_RS00475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PTUN_RS00490	COG2204	response regulator
PTUN_RS00495	COG2205	protein histidine kinase activity
PTUN_RS00510	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PTUN_RS00515	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PTUN_RS00520	COG5002	protein histidine kinase activity
PTUN_RS00520	COG0784	Response regulator, receiver
PTUN_RS00520	COG2198	Histidine kinase
PTUN_RS00540	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PTUN_RS00545	COG0235	Class ii aldolase
PTUN_RS00550	COG0436	Aminotransferase
PTUN_RS00560	COG0840	transmembrane signaling receptor activity
PTUN_RS00570	COG3118	belongs to the thioredoxin family
PTUN_RS00575	COG0513	Belongs to the DEAD box helicase family
PTUN_RS00580	COG0248	Ppx GppA phosphatase
PTUN_RS00600	COG0745	RESPONSE REGULATOR receiver
PTUN_RS00600	COG2205	protein histidine kinase activity
PTUN_RS00600	COG3292	Two component regulator propeller
PTUN_RS00630	COG0051	transcription antitermination factor activity, RNA binding
PTUN_RS00635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PTUN_RS00640	COG0088	Forms part of the polypeptide exit tunnel
PTUN_RS00645	COG0089	rRNA binding
PTUN_RS00650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PTUN_RS00655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PTUN_RS00660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PTUN_RS00665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PTUN_RS00670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PTUN_RS00675	COG0255	Belongs to the universal ribosomal protein uL29 family
PTUN_RS00680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PTUN_RS00715	COG3604	Transcriptional regulator
PTUN_RS00730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PTUN_RS00730	COG1017	nitric oxide dioxygenase activity
PTUN_RS00760	COG0529	Catalyzes the synthesis of activated sulfate
PTUN_RS00765	COG3273	potassium ion transport
PTUN_RS00765	COG0471	metal ion transport
PTUN_RS00770	COG2895	sulfate adenylyltransferase (ATP) activity
PTUN_RS00775	COG0175	sulfate reduction
PTUN_RS00780	COG1648	precorrin-2 dehydrogenase activity
PTUN_RS00780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PTUN_RS00785	COG0346	lactoylglutathione lyase activity
PTUN_RS00800	COG1584	GPR1 FUN34 yaaH family protein
PTUN_RS00815	COG4221	oxidoreductase activity
PTUN_RS00820	COG3291	Pkd domain containing protein
PTUN_RS00825	COG3720	iron ion transport
PTUN_RS00830	COG1629	transport
PTUN_RS00835	COG4558	Periplasmic binding protein
PTUN_RS00840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PTUN_RS00845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PTUN_RS00850	COG0577	efflux transmembrane transporter activity
PTUN_RS00850	COG1136	(ABC) transporter
PTUN_RS00870	COG1136	(ABC) transporter
PTUN_RS00870	COG0577	efflux transmembrane transporter activity
PTUN_RS00895	COG1785	Belongs to the alkaline phosphatase family
PTUN_RS00900	COG1785	Belongs to the alkaline phosphatase family
PTUN_RS00930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PTUN_RS00935	COG0531	amino acid
PTUN_RS00940	COG1522	sequence-specific DNA binding
PTUN_RS00955	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PTUN_RS00960	COG0519	Catalyzes the synthesis of GMP from XMP
PTUN_RS00965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PTUN_RS00980	COG3604	Transcriptional regulator
PTUN_RS00985	COG4152	abc transporter atp-binding protein
PTUN_RS01015	COG4681	YaeQ
PTUN_RS01020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PTUN_RS01055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PTUN_RS01060	COG0204	Acyl-transferase
PTUN_RS01065	COG0204	Acyl-transferase
PTUN_RS01070	COG0668	transmembrane transport
PTUN_RS01080	COG3275	phosphorelay sensor kinase activity
PTUN_RS01085	COG2059	Chromate
PTUN_RS01110	COG0640	Transcriptional regulator
PTUN_RS01125	COG0778	Nitroreductase
PTUN_RS01130	COG4555	ABC transporter
PTUN_RS01140	COG0456	acetyltransferase
PTUN_RS01170	COG2239	Acts as a magnesium transporter
PTUN_RS01175	COG2992	FlgJ-related protein
PTUN_RS01180	COG1187	pseudouridine synthase activity
PTUN_RS01195	COG0330	HflC and HflK could
PTUN_RS01200	COG0330	HflC and HflK could
PTUN_RS01215	COG0179	Fumarylacetoacetate (FAA) hydrolase
PTUN_RS01230	COG0577	efflux transmembrane transporter activity
PTUN_RS01235	COG1136	(ABC) transporter
PTUN_RS01240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PTUN_RS01250	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PTUN_RS01255	COG4989	oxidoreductase activity
PTUN_RS01275	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PTUN_RS01280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PTUN_RS01285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PTUN_RS01290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PTUN_RS01295	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PTUN_RS01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PTUN_RS01305	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PTUN_RS01310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PTUN_RS01315	COG1841	ribosomal large subunit assembly
PTUN_RS01320	COG0200	Binds to the 23S rRNA
PTUN_RS01325	COG0201	protein transport
PTUN_RS01330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PTUN_RS01335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PTUN_RS01340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PTUN_RS01345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PTUN_RS01350	COG0202	RNA polymerase activity
PTUN_RS01355	COG0203	ribosomal protein L17
PTUN_RS01385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PTUN_RS01390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PTUN_RS01395	COG0006	proline dipeptidase activity
PTUN_RS01400	COG2423	ornithine cyclodeaminase activity
PTUN_RS01450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PTUN_RS01465	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PTUN_RS01490	COG4206	TonB-dependent receptor
PTUN_RS01510	COG2204	response regulator
PTUN_RS01515	COG3852	Histidine kinase
PTUN_RS01525	COG0174	glutamine synthetase
PTUN_RS01530	COG1217	gtp-binding protein TYPA
PTUN_RS01540	COG1295	ribonuclease BN
PTUN_RS01550	COG1490	D-aminoacyl-tRNA deacylase activity
PTUN_RS01560	COG0456	acetyltransferase
PTUN_RS01575	COG0019	diaminopimelate decarboxylase activity
PTUN_RS01585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PTUN_RS01610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PTUN_RS01615	COG0129	dihydroxy-acid dehydratase activity
PTUN_RS01620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PTUN_RS01625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PTUN_RS01635	COG0288	reversible hydration of carbon dioxide
PTUN_RS01650	COG5001	Diguanylate cyclase
PTUN_RS01665	COG0612	Peptidase, M16
PTUN_RS01670	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PTUN_RS01675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PTUN_RS01675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PTUN_RS01680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PTUN_RS01710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PTUN_RS01715	COG2814	Major facilitator Superfamily
PTUN_RS01720	COG0629	single-stranded DNA binding
PTUN_RS01765	COG3409	Peptidoglycan-binding domain 1 protein
PTUN_RS01765	COG3267	Type II secretory pathway component ExeA
PTUN_RS01775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PTUN_RS01780	COG1459	type II secretion system
PTUN_RS01790	COG2165	general secretion pathway protein
PTUN_RS01825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PTUN_RS01830	COG1077	Cell shape determining protein MreB Mrl
PTUN_RS01835	COG1792	Involved in formation and maintenance of cell shape
PTUN_RS01840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PTUN_RS01845	COG0424	maF-like protein
PTUN_RS01850	COG1530	ribonuclease E activity
PTUN_RS01855	COG3164	Protein of unknown function
PTUN_RS01860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PTUN_RS01865	COG0312	modulator of DNA gyrase
PTUN_RS01875	COG3634	alkyl hydroperoxide reductase activity
PTUN_RS01880	COG0450	alkyl hydroperoxide reductase
PTUN_RS01920	COG0584	glycerophosphoryl diester phosphodiesterase
PTUN_RS01940	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
PTUN_RS01945	COG2814	Major facilitator Superfamily
PTUN_RS01950	COG3122	Protein conserved in bacteria
PTUN_RS01965	COG4948	Mandelate Racemase Muconate Lactonizing
PTUN_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS01985	COG1388	LysM domain
PTUN_RS01985	COG0741	lytic transglycosylase activity
PTUN_RS02010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PTUN_RS02020	COG2824	Alkylphosphonate utilization operon protein PhnA
PTUN_RS02030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PTUN_RS02040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PTUN_RS02045	COG0640	Transcriptional regulator
PTUN_RS02075	COG2814	Major facilitator Superfamily
PTUN_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS02110	COG0436	Aminotransferase
PTUN_RS02125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PTUN_RS02135	COG5433	transposase activity
PTUN_RS02140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PTUN_RS02150	COG0339	signal peptide processing
PTUN_RS02160	COG0742	ribosomal rna small subunit methyltransferase
PTUN_RS02175	COG1528	Iron-storage protein
PTUN_RS02180	COG2081	HI0933 family
PTUN_RS02185	COG0339	signal peptide processing
PTUN_RS02255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PTUN_RS02285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PTUN_RS02295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PTUN_RS02300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PTUN_RS02305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PTUN_RS02310	COG0723	plastoquinol--plastocyanin reductase activity
PTUN_RS02315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PTUN_RS02320	COG2857	Cytochrome c1
PTUN_RS02325	COG0625	glutathione transferase activity
PTUN_RS02330	COG2969	positive regulation of protein catabolic process
PTUN_RS02350	COG2823	Periplasmic or secreted lipoprotein
PTUN_RS02360	COG0792	nuclease activity
PTUN_RS02365	COG3107	peptidoglycan biosynthetic process
PTUN_RS02370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PTUN_RS02380	COG3706	GGDEF domain
PTUN_RS02380	COG2203	Gaf domain
PTUN_RS02380	COG4251	negative regulation of phosphorylation
PTUN_RS02380	COG5001	Diguanylate cyclase
PTUN_RS02385	COG0784	Response regulator, receiver
PTUN_RS02385	COG5002	protein histidine kinase activity
PTUN_RS02385	COG2205	protein histidine kinase activity
PTUN_RS02390	COG5002	protein histidine kinase activity
PTUN_RS02390	COG0784	Response regulator, receiver
PTUN_RS02390	COG2205	protein histidine kinase activity
PTUN_RS02395	COG1280	lysine exporter protein (LysE YggA)
PTUN_RS02410	COG2001	Belongs to the MraZ family
PTUN_RS02415	COG0275	rRNA processing
PTUN_RS02420	COG3116	cell division
PTUN_RS02425	COG0768	penicillin binding
PTUN_RS02430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PTUN_RS02435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PTUN_RS02440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PTUN_RS02445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PTUN_RS02450	COG0772	Belongs to the SEDS family
PTUN_RS02455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PTUN_RS02460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PTUN_RS02465	COG1181	Belongs to the D-alanine--D-alanine ligase family
PTUN_RS02470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PTUN_RS02475	COG0849	cell division
PTUN_RS02480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PTUN_RS02485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PTUN_RS02495	COG0739	heme binding
PTUN_RS02500	COG0653	protein targeting
PTUN_RS02505	COG0494	nUDIX hydrolase
PTUN_RS02515	COG3590	peptidase
PTUN_RS02535	COG0840	transmembrane signaling receptor activity
PTUN_RS02540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PTUN_RS02550	COG1228	amidohydrolase
PTUN_RS02565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PTUN_RS02590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PTUN_RS02595	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PTUN_RS02605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PTUN_RS02610	COG0254	rRNA binding
PTUN_RS02630	COG2832	Protein of unknown function (DUF454)
PTUN_RS02635	COG0668	transmembrane transport
PTUN_RS02645	COG1596	polysaccharide export
PTUN_RS02650	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
PTUN_RS02665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PTUN_RS02670	COG1459	type II secretion system
PTUN_RS02710	COG1450	Type ii and iii secretion system protein
PTUN_RS02745	COG0438	transferase activity, transferring glycosyl groups
PTUN_RS02760	COG1088	dTDP-glucose 4,6-dehydratase activity
PTUN_RS02790	COG1215	transferase activity, transferring glycosyl groups
PTUN_RS02830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PTUN_RS02860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PTUN_RS02875	COG2022	thiamine diphosphate biosynthetic process
PTUN_RS02885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PTUN_RS02895	COG0688	phosphatidylethanolamine metabolic process
PTUN_RS02900	COG1162	GTPase activity
PTUN_RS02905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PTUN_RS02940	COG4999	Histidine kinase
PTUN_RS02940	COG2205	protein histidine kinase activity
PTUN_RS02940	COG3850	Histidine kinase
PTUN_RS02940	COG3437	response regulator, receiver
PTUN_RS02950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PTUN_RS02955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PTUN_RS02955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PTUN_RS02960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PTUN_RS02960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PTUN_RS02965	COG0802	atpase or kinase
PTUN_RS02970	COG0860	N-Acetylmuramoyl-L-alanine amidase
PTUN_RS02975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PTUN_RS02980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PTUN_RS02990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PTUN_RS02995	COG0330	HflC and HflK could
PTUN_RS03000	COG0330	HflC and HflK could
PTUN_RS03010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PTUN_RS03015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PTUN_RS03020	COG0557	exoribonuclease II activity
PTUN_RS03025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PTUN_RS03030	COG0360	Binds together with S18 to 16S ribosomal RNA
PTUN_RS03035	COG2965	DNA replication, synthesis of RNA primer
PTUN_RS03040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PTUN_RS03045	COG0359	binds to the 23S rRNA
PTUN_RS03090	COG0305	Participates in initiation and elongation during chromosome replication
PTUN_RS03095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PTUN_RS03110	COG0735	belongs to the Fur family
PTUN_RS03140	COG1396	sequence-specific DNA binding
PTUN_RS03220	COG4695	Portal protein
PTUN_RS03360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PTUN_RS03365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PTUN_RS03375	COG1842	Phage shock protein A
PTUN_RS03415	COG3300	MHYT domain
PTUN_RS03415	COG5001	Diguanylate cyclase
PTUN_RS03420	COG1032	radical SAM domain protein
PTUN_RS03425	COG0823	Involved in the tonB-independent uptake of proteins
PTUN_RS03425	COG1506	peptidase
PTUN_RS03425	COG4946	Tricorn protease homolog
PTUN_RS03435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PTUN_RS03440	COG2003	Belongs to the UPF0758 family
PTUN_RS03450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PTUN_RS03475	COG1280	lysine exporter protein (LysE YggA)
PTUN_RS03490	COG0123	including yeast histone deacetylase and acetoin utilization protein
PTUN_RS03495	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PTUN_RS03500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PTUN_RS03505	COG0237	dephospho-CoA kinase activity
PTUN_RS03510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PTUN_RS03515	COG1459	type II secretion system
PTUN_RS03520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PTUN_RS03535	COG3023	N-Acetylmuramoyl-L-alanine amidase
PTUN_RS03545	COG2186	Transcriptional regulator
PTUN_RS03550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PTUN_RS03555	COG0508	dehydrogenase complex catalyzes the overall conversion of
PTUN_RS03560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PTUN_RS03565	COG3148	PFAM DTW domain containing protein
PTUN_RS03570	COG1840	ABC-type Fe3 transport system, periplasmic component
PTUN_RS03580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PTUN_RS03590	COG1438	arginine binding
PTUN_RS03595	COG0039	L-malate dehydrogenase activity
PTUN_RS03600	COG0142	geranyltranstransferase activity
PTUN_RS03605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PTUN_RS03610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PTUN_RS03615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PTUN_RS03635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PTUN_RS03645	COG0788	formyltetrahydrofolate deformylase activity
PTUN_RS03655	COG0784	Response regulator, receiver
PTUN_RS03655	COG2198	Histidine kinase
PTUN_RS03655	COG5002	protein histidine kinase activity
PTUN_RS03665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PTUN_RS03670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PTUN_RS03670	COG0517	IMP dehydrogenase activity
PTUN_RS03680	COG3591	Belongs to the peptidase S1B family
PTUN_RS03680	COG4990	cell redox homeostasis
PTUN_RS03695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PTUN_RS03700	COG1410	methionine synthase
PTUN_RS03700	COG0646	methionine synthase
PTUN_RS03705	COG0646	methionine synthase
PTUN_RS03705	COG1410	methionine synthase
PTUN_RS03720	COG0762	integral membrane protein
PTUN_RS03725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PTUN_RS03730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PTUN_RS03750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PTUN_RS03755	COG1678	Uncharacterized ACR, COG1678
PTUN_RS03760	COG0189	ligase activity
PTUN_RS03765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PTUN_RS03800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PTUN_RS03810	COG1560	Kdo2-lipid A biosynthetic process
PTUN_RS03815	COG1538	Outer membrane efflux protein
PTUN_RS03820	COG0494	nUDIX hydrolase
PTUN_RS03835	COG3150	esterase
PTUN_RS03840	COG0187	DNA topoisomerase II activity
PTUN_RS03845	COG2199	diguanylate cyclase activity
PTUN_RS03855	COG0204	Acyl-transferase
PTUN_RS03860	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PTUN_RS03865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PTUN_RS03875	COG2067	long-chain fatty acid transport protein
PTUN_RS03880	COG0525	valine-tRNA ligase activity
PTUN_RS03885	COG2927	DNA polymerase III (CHI subunit)
PTUN_RS03890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PTUN_RS03895	COG0795	lipopolysaccharide-transporting ATPase activity
PTUN_RS03900	COG0795	lipopolysaccharide-transporting ATPase activity
PTUN_RS03925	COG1764	response to oxidative stress
PTUN_RS03970	COG1462	curli production assembly transport component CsgG
PTUN_RS03975	COG2197	response regulator
PTUN_RS03985	COG0612	Peptidase, M16
PTUN_RS04010	COG2815	serine threonine protein kinase
PTUN_RS04010	COG0515	serine threonine protein kinase
PTUN_RS04015	COG2814	Major facilitator Superfamily
PTUN_RS04020	COG1045	serine acetyltransferase
PTUN_RS04025	COG0840	transmembrane signaling receptor activity
PTUN_RS04040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PTUN_RS04045	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PTUN_RS04050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PTUN_RS04055	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PTUN_RS04060	COG3178	'Phosphotransferase
PTUN_RS04065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PTUN_RS04070	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PTUN_RS04085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PTUN_RS04090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PTUN_RS04095	COG3706	GGDEF domain
PTUN_RS04095	COG5001	Diguanylate cyclase
PTUN_RS04095	COG4251	negative regulation of phosphorylation
PTUN_RS04095	COG2203	Gaf domain
PTUN_RS04105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PTUN_RS04110	COG1234	tRNA 3'-trailer cleavage
PTUN_RS04125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PTUN_RS04130	COG0789	Transcriptional regulator
PTUN_RS04145	COG2133	pyrroloquinoline quinone binding
PTUN_RS04185	COG3313	Fe-S protein
PTUN_RS04215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PTUN_RS04220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PTUN_RS04220	COG1042	CoA-binding domain protein
PTUN_RS04220	COG0045	succinate-CoA ligase (ADP-forming) activity
PTUN_RS04280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PTUN_RS04295	COG0488	(ABC) transporter
PTUN_RS04300	COG2199	diguanylate cyclase activity
PTUN_RS04305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PTUN_RS04310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PTUN_RS04315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PTUN_RS04315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PTUN_RS04330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PTUN_RS04335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PTUN_RS04345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PTUN_RS04350	COG3706	GGDEF domain
PTUN_RS04355	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PTUN_RS04360	COG0142	geranyltranstransferase activity
PTUN_RS04365	COG1722	exodeoxyribonuclease VII activity
PTUN_RS04370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PTUN_RS04375	COG2885	chlorophyll binding
PTUN_RS04435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PTUN_RS04440	COG3938	Belongs to the proline racemase family
PTUN_RS04470	COG1595	DNA-templated transcription, initiation
PTUN_RS04480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PTUN_RS04490	COG2137	regulation of response to DNA damage stimulus
PTUN_RS04495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PTUN_RS04500	COG0527	aspartate kinase activity
PTUN_RS04505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PTUN_RS04510	COG0668	transmembrane transport
PTUN_RS04520	COG1280	lysine exporter protein (LysE YggA)
PTUN_RS04525	COG3264	Mechanosensitive ion channel
PTUN_RS04525	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PTUN_RS04545	COG3099	Belongs to the UPF0263 family
PTUN_RS04555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PTUN_RS04560	COG1024	Enoyl-CoA hydratase
PTUN_RS04565	COG1380	Effector of murein hydrolase LrgA
PTUN_RS04570	COG1346	cytolysis
PTUN_RS04580	COG0513	Belongs to the DEAD box helicase family
PTUN_RS04585	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PTUN_RS04600	COG4974	Belongs to the 'phage' integrase family
PTUN_RS04605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PTUN_RS04620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PTUN_RS04700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PTUN_RS04710	COG1469	GTP cyclohydrolase I activity
PTUN_RS04725	COG2198	Histidine kinase
PTUN_RS04725	COG0784	Response regulator, receiver
PTUN_RS04725	COG5002	protein histidine kinase activity
PTUN_RS04730	COG0745	RESPONSE REGULATOR receiver
PTUN_RS04740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PTUN_RS04740	COG4191	Histidine kinase
PTUN_RS04745	COG2813	Specifically methylates the guanine in position
PTUN_RS04750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PTUN_RS04760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PTUN_RS04840	COG0006	proline dipeptidase activity
PTUN_RS04845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PTUN_RS04850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PTUN_RS04875	COG3710	Transcriptional regulator
PTUN_RS04875	COG0457	Tetratricopeptide repeat
PTUN_RS04885	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PTUN_RS04890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PTUN_RS04895	COG0509	glycine decarboxylation via glycine cleavage system
PTUN_RS04900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PTUN_RS04900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PTUN_RS04940	COG4249	Peptidase C14 caspase catalytic subunit p20
PTUN_RS04965	COG0730	response to heat
PTUN_RS04990	COG2197	response regulator
PTUN_RS04995	COG4585	Histidine kinase
PTUN_RS05010	COG2986	histidine ammonia-lyase
PTUN_RS05015	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PTUN_RS05045	COG1234	tRNA 3'-trailer cleavage
PTUN_RS05065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PTUN_RS05080	COG0415	Belongs to the DNA photolyase family
PTUN_RS05085	COG0798	PFAM Bile acid sodium symporter
PTUN_RS05095	COG2315	Protein conserved in bacteria
PTUN_RS05100	COG2211	Major facilitator Superfamily
PTUN_RS05110	COG0339	signal peptide processing
PTUN_RS05120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PTUN_RS05140	COG4771	TonB-dependent receptor
PTUN_RS05155	COG0546	phosphoglycolate phosphatase activity
PTUN_RS05160	COG1793	dna ligase
PTUN_RS05165	COG0443	Heat shock 70 kDa protein
PTUN_RS05170	COG2840	Smr protein MutS2
PTUN_RS05175	COG2890	protein-(glutamine-N5) methyltransferase activity
PTUN_RS05180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PTUN_RS05185	COG0583	DNA-binding transcription factor activity
PTUN_RS05190	COG0625	glutathione transferase activity
PTUN_RS05205	COG1253	flavin adenine dinucleotide binding
PTUN_RS05215	COG0513	Belongs to the DEAD box helicase family
PTUN_RS05235	COG2204	response regulator
PTUN_RS05245	COG0071	Belongs to the small heat shock protein (HSP20) family
PTUN_RS05260	COG3447	MASE1 domain protein
PTUN_RS05260	COG5002	protein histidine kinase activity
PTUN_RS05260	COG5001	Diguanylate cyclase
PTUN_RS05265	COG0456	acetyltransferase
PTUN_RS05275	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PTUN_RS05280	COG1278	Cold shock
PTUN_RS05305	COG3291	Pkd domain containing protein
PTUN_RS05325	COG1518	maintenance of DNA repeat elements
PTUN_RS05330	COG1203	CRISPR-associated helicase, Cas3
PTUN_RS05395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PTUN_RS05410	COG0517	IMP dehydrogenase activity
PTUN_RS05415	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PTUN_RS05415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PTUN_RS05425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PTUN_RS05430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PTUN_RS05445	COG0101	tRNA pseudouridine synthase activity
PTUN_RS05450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PTUN_RS05455	COG0285	dihydrofolate synthase activity
PTUN_RS05465	COG1286	toxin biosynthetic process
PTUN_RS05470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PTUN_RS05485	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PTUN_RS05490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PTUN_RS05495	COG0215	cysteine-tRNA ligase activity
PTUN_RS05500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PTUN_RS05540	COG0544	peptidyl-prolyl cis-trans isomerase activity
PTUN_RS05545	COG0740	serine-type endopeptidase activity
PTUN_RS05550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PTUN_RS05555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PTUN_RS05560	COG0776	regulation of translation
PTUN_RS05565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PTUN_RS05570	COG0077	Prephenate dehydratase
PTUN_RS05570	COG1605	Chorismate mutase
PTUN_RS05580	COG0745	RESPONSE REGULATOR receiver
PTUN_RS05585	COG0023	Translation Initiation Factor
PTUN_RS05605	COG1448	Aminotransferase
PTUN_RS05610	COG3141	response to X-ray
PTUN_RS05615	COG1555	photosystem II stabilization
PTUN_RS05625	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PTUN_RS05640	COG0450	alkyl hydroperoxide reductase
PTUN_RS05645	COG4206	TonB-dependent receptor
PTUN_RS05650	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PTUN_RS05655	COG2867	negative regulation of translational initiation
PTUN_RS05660	COG2914	Belongs to the UPF0125 (RnfH) family
PTUN_RS05665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PTUN_RS05685	COG2837	iron assimilation
PTUN_RS05690	COG0840	transmembrane signaling receptor activity
PTUN_RS05695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PTUN_RS05700	COG0583	DNA-binding transcription factor activity
PTUN_RS05705	COG3713	MltA-interacting MipA family protein
PTUN_RS05715	COG0745	RESPONSE REGULATOR receiver
PTUN_RS05720	COG2205	protein histidine kinase activity
PTUN_RS05735	COG4772	TonB-dependent receptor
PTUN_RS05745	COG2195	Cleaves the N-terminal amino acid of tripeptides
PTUN_RS05765	COG4326	sporulation control protein
PTUN_RS05775	COG2153	protein acetylation
PTUN_RS05780	COG0733	neurotransmitter:sodium symporter activity
PTUN_RS05785	COG2205	protein histidine kinase activity
PTUN_RS05820	COG1534	Rna-binding protein
PTUN_RS05825	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PTUN_RS05830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PTUN_RS05835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PTUN_RS05840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PTUN_RS05845	COG0149	triose-phosphate isomerase activity
PTUN_RS05850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PTUN_RS05900	COG4536	flavin adenine dinucleotide binding
PTUN_RS05905	COG4137	Cytochrome C assembly protein
PTUN_RS05910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PTUN_RS05915	COG0228	four-way junction DNA binding
PTUN_RS05920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PTUN_RS05925	COG0336	Belongs to the RNA methyltransferase TrmD family
PTUN_RS05930	COG0335	large ribosomal subunit rRNA binding
PTUN_RS05935	COG1605	Chorismate mutase
PTUN_RS05935	COG0287	Prephenate dehydrogenase
PTUN_RS05940	COG4172	Belongs to the ABC transporter superfamily
PTUN_RS05945	COG4172	Belongs to the ABC transporter superfamily
PTUN_RS05960	COG0747	negative chemotaxis
PTUN_RS05965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PTUN_RS05970	COG1842	Phage shock protein A
PTUN_RS05980	COG1983	PspC domain protein
PTUN_RS05985	COG3106	COG3106 Predicted ATPase
PTUN_RS05990	COG3768	UPF0283 membrane protein
PTUN_RS05995	COG0626	cystathionine gamma-synthase activity
PTUN_RS06005	COG2154	pterin-4-alpha-carbinolamine dehydratase
PTUN_RS06010	COG3590	peptidase
PTUN_RS06020	COG0514	ATP-dependent DNA helicase (RecQ)
PTUN_RS06040	COG0779	Required for maturation of 30S ribosomal subunits
PTUN_RS06045	COG0195	Participates in both transcription termination and antitermination
PTUN_RS06050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PTUN_RS06055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PTUN_RS06060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PTUN_RS06065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PTUN_RS06070	COG1185	polyribonucleotide nucleotidyltransferase activity
PTUN_RS06085	COG2111	Na H antiporter
PTUN_RS06085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PTUN_RS06090	COG1006	Multisubunit Na H antiporter MnhC subunit
PTUN_RS06095	COG0651	ATP synthesis coupled electron transport
PTUN_RS06100	COG1863	multisubunit Na H antiporter MnhE subunit
PTUN_RS06105	COG2212	antiporter activity
PTUN_RS06120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PTUN_RS06125	COG0321	lipoyl(octanoyl) transferase activity
PTUN_RS06130	COG2921	Belongs to the UPF0250 family
PTUN_RS06135	COG1686	Belongs to the peptidase S11 family
PTUN_RS06140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PTUN_RS06145	COG0772	Belongs to the SEDS family
PTUN_RS06150	COG0768	penicillin binding
PTUN_RS06155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PTUN_RS06160	COG0799	negative regulation of ribosome biogenesis
PTUN_RS06165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PTUN_RS06175	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PTUN_RS06180	COG0495	leucyl-tRNA aminoacylation
PTUN_RS06195	COG1067	ATP-dependent peptidase activity
PTUN_RS06200	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PTUN_RS06205	COG4535	Mg2 and Co2 transporter CorC
PTUN_RS06210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PTUN_RS06215	COG1702	phosphate starvation-inducible protein PhoH
PTUN_RS06220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PTUN_RS06225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PTUN_RS06280	COG0012	GTP binding
PTUN_RS06285	COG0193	aminoacyl-tRNA hydrolase activity
PTUN_RS06290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PTUN_RS06295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PTUN_RS06300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PTUN_RS06305	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PTUN_RS06310	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PTUN_RS06315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PTUN_RS06320	COG2890	protein-(glutamine-N5) methyltransferase activity
PTUN_RS06325	COG3437	response regulator, receiver
PTUN_RS06325	COG0784	Response regulator, receiver
PTUN_RS06330	COG2912	Transglutaminase-like superfamily
PTUN_RS06335	COG5505	Protein of unknown function (DUF819)
PTUN_RS06340	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PTUN_RS06350	COG0583	DNA-binding transcription factor activity
PTUN_RS06360	COG2363	Small membrane protein
PTUN_RS06365	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PTUN_RS06465	COG1683	Conserved Protein
PTUN_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS06485	COG3437	response regulator, receiver
PTUN_RS06490	COG0784	Response regulator, receiver
PTUN_RS06490	COG2198	Histidine kinase
PTUN_RS06490	COG5002	protein histidine kinase activity
PTUN_RS06500	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PTUN_RS06505	COG1196	nuclear chromosome segregation
PTUN_RS06515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PTUN_RS06615	COG0346	lactoylglutathione lyase activity
PTUN_RS06645	COG2311	Membrane
PTUN_RS06650	COG1309	transcriptional regulator
PTUN_RS06670	COG2207	Transcriptional regulator
PTUN_RS06670	COG1917	Cupin 2, conserved barrel domain protein
PTUN_RS06755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PTUN_RS06760	COG4660	Part of a membrane complex involved in electron transport
PTUN_RS06765	COG4659	FMN binding
PTUN_RS06770	COG4658	electron transport chain
PTUN_RS06780	COG2878	Part of a membrane complex involved in electron transport
PTUN_RS06785	COG4657	Part of a membrane complex involved in electron transport
PTUN_RS06790	COG2200	EAL domain
PTUN_RS06815	COG0501	Belongs to the peptidase M48B family
PTUN_RS06825	COG0534	Mate efflux family protein
PTUN_RS06830	COG0556	nucleotide-excision repair
PTUN_RS06835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PTUN_RS06850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PTUN_RS06855	COG0602	queuosine metabolic process
PTUN_RS06870	COG1393	Belongs to the ArsC family
PTUN_RS06875	COG4783	chaperone-mediated protein folding
PTUN_RS06895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PTUN_RS06900	COG2716	regulation of RNA biosynthetic process
PTUN_RS06910	COG3314	Sporulation integral membrane protein YlbJ
PTUN_RS06925	COG1104	cysteine desulfurase activity
PTUN_RS06930	COG1609	Transcriptional regulator
PTUN_RS06935	COG0166	Belongs to the GPI family
PTUN_RS06940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PTUN_RS06945	COG0363	glucosamine-6-phosphate deaminase activity
PTUN_RS07005	COG1505	serine-type exopeptidase activity
PTUN_RS07040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PTUN_RS07055	COG1643	Atp-dependent helicase
PTUN_RS07075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PTUN_RS07080	COG3724	N-succinylarginine dihydrolase activity
PTUN_RS07100	COG4771	TonB-dependent receptor
PTUN_RS07110	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PTUN_RS07115	COG1011	Hydrolase
PTUN_RS07145	COG1254	Belongs to the acylphosphatase family
PTUN_RS07160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PTUN_RS07175	COG4181	ATPase activity
PTUN_RS07185	COG1090	epimerase
PTUN_RS07190	COG0628	permease
PTUN_RS07220	COG2350	Protein conserved in bacteria
PTUN_RS07225	COG0733	neurotransmitter:sodium symporter activity
PTUN_RS07235	COG2917	probably involved in intracellular septation
PTUN_RS07250	COG0134	indole-3-glycerol-phosphate synthase activity
PTUN_RS07250	COG0135	phosphoribosylanthranilate isomerase activity
PTUN_RS07255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PTUN_RS07260	COG0512	Glutamine amidotransferase of anthranilate synthase
PTUN_RS07265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PTUN_RS07270	COG0613	PHP domain protein
PTUN_RS07275	COG0009	L-threonylcarbamoyladenylate synthase
PTUN_RS07285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PTUN_RS07290	COG1187	pseudouridine synthase activity
PTUN_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS07305	COG0616	signal peptide processing
PTUN_RS07310	COG1301	dicarboxylic acid transport
PTUN_RS07320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PTUN_RS07330	COG5002	protein histidine kinase activity
PTUN_RS07340	COG0583	DNA-binding transcription factor activity
PTUN_RS07345	COG1760	l-serine dehydratase
PTUN_RS07365	COG1506	peptidase
PTUN_RS07365	COG0823	Involved in the tonB-independent uptake of proteins
PTUN_RS07375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PTUN_RS07405	COG1643	Atp-dependent helicase
PTUN_RS07410	COG3228	Belongs to the MtfA family
PTUN_RS07415	COG4946	Tricorn protease homolog
PTUN_RS07415	COG0823	Involved in the tonB-independent uptake of proteins
PTUN_RS07415	COG1506	peptidase
PTUN_RS07420	COG2925	Exonuclease
PTUN_RS07455	COG0516	GMP reductase activity
PTUN_RS07455	COG0517	IMP dehydrogenase activity
PTUN_RS07460	COG2971	BadF BadG BcrA BcrD
PTUN_RS07465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PTUN_RS07475	COG0363	glucosamine-6-phosphate deaminase activity
PTUN_RS07490	COG0626	cystathionine gamma-synthase activity
PTUN_RS07500	COG1131	(ABC) transporter
PTUN_RS07515	COG1960	acyl-CoA dehydrogenase activity
PTUN_RS07535	COG1283	sodium-dependent phosphate transmembrane transporter activity
PTUN_RS07545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PTUN_RS07545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PTUN_RS07555	COG0717	Belongs to the dCTP deaminase family
PTUN_RS07560	COG5001	Diguanylate cyclase
PTUN_RS07560	COG4251	negative regulation of phosphorylation
PTUN_RS07560	COG3706	GGDEF domain
PTUN_RS07560	COG2203	Gaf domain
PTUN_RS07585	COG0436	Aminotransferase
PTUN_RS07590	COG1876	peptidase activity
PTUN_RS07595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PTUN_RS07600	COG1393	Belongs to the ArsC family
PTUN_RS07615	COG0857	belongs to the CobB CobQ family
PTUN_RS07615	COG0280	phosphate acetyltransferase
PTUN_RS07620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PTUN_RS07635	COG2226	methyltransferase
PTUN_RS07650	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PTUN_RS07655	COG1074	ATP-dependent DNA helicase activity
PTUN_RS07660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PTUN_RS07695	COG0745	RESPONSE REGULATOR receiver
PTUN_RS07710	COG3012	SEC-C Motif Domain Protein
PTUN_RS07735	COG5002	protein histidine kinase activity
PTUN_RS07735	COG5001	Diguanylate cyclase
PTUN_RS07750	COG1943	Transposase
PTUN_RS07780	COG0438	transferase activity, transferring glycosyl groups
PTUN_RS07845	COG4464	protein tyrosine phosphatase activity
PTUN_RS07860	COG2252	PERMEase
PTUN_RS07865	COG0840	transmembrane signaling receptor activity
PTUN_RS07875	COG1979	alcohol dehydrogenase
PTUN_RS07885	COG0366	Alpha amylase catalytic
PTUN_RS07900	COG0366	Alpha amylase catalytic
PTUN_RS07920	COG1609	Transcriptional regulator
PTUN_RS07925	COG0837	glucose binding
PTUN_RS07930	COG1609	Transcriptional regulator
PTUN_RS07945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PTUN_RS07965	COG3386	PFAM SMP-30 Gluconolaconase
PTUN_RS07975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PTUN_RS07985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PTUN_RS07990	COG1288	antiporter activity
PTUN_RS08010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PTUN_RS08015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PTUN_RS08020	COG2957	Belongs to the agmatine deiminase family
PTUN_RS08050	COG1966	Carbon starvation protein
PTUN_RS08085	COG4206	TonB-dependent receptor
PTUN_RS08095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PTUN_RS08100	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PTUN_RS08110	COG0659	secondary active sulfate transmembrane transporter activity
PTUN_RS08115	COG4591	ABC-type transport system involved in lipoprotein release permease component
PTUN_RS08120	COG1136	(ABC) transporter
PTUN_RS08125	COG4591	ABC-type transport system involved in lipoprotein release permease component
PTUN_RS08140	COG2850	peptidyl-arginine hydroxylation
PTUN_RS08145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PTUN_RS08150	COG2915	High frequency lysogenization protein hflD homolog
PTUN_RS08155	COG0482	sulfurtransferase activity
PTUN_RS08165	COG1187	pseudouridine synthase activity
PTUN_RS08175	COG1278	Cold shock
PTUN_RS08180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PTUN_RS08185	COG0542	response to heat
PTUN_RS08200	COG1252	NADH dehydrogenase
PTUN_RS08220	COG0668	transmembrane transport
PTUN_RS08225	COG0210	DNA helicase
PTUN_RS08230	COG2203	Gaf domain
PTUN_RS08230	COG3706	GGDEF domain
PTUN_RS08230	COG4251	negative regulation of phosphorylation
PTUN_RS08230	COG5001	Diguanylate cyclase
PTUN_RS08235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PTUN_RS08240	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PTUN_RS08245	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PTUN_RS08250	COG0492	ferredoxin-NADP+ reductase activity
PTUN_RS08255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PTUN_RS08260	COG0686	Belongs to the AlaDH PNT family
PTUN_RS08270	COG0531	amino acid
PTUN_RS08270	COG1674	ftsk spoiiie
PTUN_RS08275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PTUN_RS08280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PTUN_RS08285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PTUN_RS08290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PTUN_RS08295	COG2920	part of a sulfur-relay system
PTUN_RS08305	COG2923	Belongs to the DsrF TusC family
PTUN_RS08315	COG0670	Belongs to the BI1 family
PTUN_RS08335	COG1956	GAF domain-containing protein
PTUN_RS08345	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PTUN_RS08355	COG1757	Na H antiporter
PTUN_RS08360	COG0308	aminopeptidase N
PTUN_RS08385	COG2409	Drug exporters of the RND superfamily
PTUN_RS08390	COG2902	Dehydrogenase
PTUN_RS08395	COG0167	dihydroorotate dehydrogenase activity
PTUN_RS08405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PTUN_RS08405	COG0116	Belongs to the methyltransferase superfamily
PTUN_RS08415	COG0488	(ABC) transporter
PTUN_RS08430	COG0658	competence protein
PTUN_RS08430	COG2333	competence protein COMEC
PTUN_RS08435	COG1132	(ABC) transporter
PTUN_RS08440	COG1663	tetraacyldisaccharide 4'-kinase activity
PTUN_RS08445	COG2835	tetraacyldisaccharide 4'-kinase activity
PTUN_RS08450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PTUN_RS08455	COG0564	pseudouridine synthase activity
PTUN_RS08460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PTUN_RS08465	COG2166	iron-sulfur cluster assembly
PTUN_RS08470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PTUN_RS08485	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PTUN_RS08490	COG1053	succinate dehydrogenase
PTUN_RS08500	COG0567	Dehydrogenase, E1 component
PTUN_RS08505	COG0508	dehydrogenase complex catalyzes the overall conversion of
PTUN_RS08510	COG0045	succinate-CoA ligase (ADP-forming) activity
PTUN_RS08520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PTUN_RS08530	COG0716	FMN binding
PTUN_RS08545	COG0596	Alpha beta hydrolase
PTUN_RS08550	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PTUN_RS08555	COG0033	Phosphoglucomutase
PTUN_RS08560	COG2988	succinylglutamate desuccinylase activity
PTUN_RS08570	COG0022	dehydrogenase e1 component
PTUN_RS08600	COG4555	ABC transporter
PTUN_RS08605	COG1668	transmembrane transport
PTUN_RS08615	COG0442	prolyl-tRNA aminoacylation
PTUN_RS08620	COG1720	tRNA m6t6A37 methyltransferase activity
PTUN_RS08645	COG0123	including yeast histone deacetylase and acetoin utilization protein
PTUN_RS08670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PTUN_RS08675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PTUN_RS08680	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PTUN_RS08685	COG1231	oxidoreductase activity
PTUN_RS08690	COG0534	Mate efflux family protein
PTUN_RS08710	COG0017	Asparaginyl-tRNA synthetase
PTUN_RS08730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PTUN_RS08735	COG0156	8-amino-7-oxononanoate synthase activity
PTUN_RS08745	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PTUN_RS08750	COG0501	Belongs to the peptidase M48B family
PTUN_RS08765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PTUN_RS08770	COG0488	(ABC) transporter
PTUN_RS08775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PTUN_RS08780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PTUN_RS08785	COG2855	membrane
PTUN_RS08805	COG0405	Gamma-glutamyltransferase
PTUN_RS08810	COG0281	malic enzyme
PTUN_RS08825	COG0714	Associated with various cellular activities
PTUN_RS08840	COG2056	Na+-H+ antiporter family
PTUN_RS08845	COG1607	acyl-coa hydrolase
PTUN_RS08860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PTUN_RS08865	COG3130	regulation of translation
PTUN_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS08885	COG1024	Enoyl-CoA hydratase
PTUN_RS08885	COG1250	3-hydroxyacyl-CoA dehydrogenase
PTUN_RS08890	COG1024	Enoyl-CoA hydratase
PTUN_RS08915	COG1960	acyl-CoA dehydrogenase activity
PTUN_RS08920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PTUN_RS08940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PTUN_RS08960	COG5002	protein histidine kinase activity
PTUN_RS08960	COG0784	Response regulator, receiver
PTUN_RS08960	COG2205	protein histidine kinase activity
PTUN_RS08965	COG0367	asparagine synthase
PTUN_RS08970	COG1054	Belongs to the UPF0176 family
PTUN_RS08975	COG0513	Belongs to the DEAD box helicase family
PTUN_RS08990	COG0284	orotidine-5'-phosphate decarboxylase activity
PTUN_RS08995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PTUN_RS09005	COG0776	regulation of translation
PTUN_RS09010	COG0539	negative regulation of cytoplasmic translation
PTUN_RS09015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PTUN_RS09020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PTUN_RS09025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PTUN_RS09035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PTUN_RS09045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PTUN_RS09060	COG4681	YaeQ
PTUN_RS09070	COG0545	Peptidyl-prolyl cis-trans isomerase
PTUN_RS09090	COG0471	metal ion transport
PTUN_RS09095	COG1472	Belongs to the glycosyl hydrolase 3 family
PTUN_RS09100	COG0778	Nitroreductase
PTUN_RS09110	COG0446	pyridine nucleotide-disulphide oxidoreductase
PTUN_RS09110	COG1902	pentaerythritol trinitrate reductase activity
PTUN_RS09115	COG0616	signal peptide processing
PTUN_RS09120	COG0252	asparaginase activity
PTUN_RS09125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PTUN_RS09130	COG0469	pyruvate kinase activity
PTUN_RS09135	COG0205	6-phosphofructokinase activity
PTUN_RS09140	COG3279	Response regulator of the LytR AlgR family
PTUN_RS09145	COG3275	phosphorelay sensor kinase activity
PTUN_RS09150	COG0659	secondary active sulfate transmembrane transporter activity
PTUN_RS09155	COG1522	sequence-specific DNA binding
PTUN_RS09160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PTUN_RS09175	COG0300	oxidoreductase activity
PTUN_RS09180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PTUN_RS09185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PTUN_RS09190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PTUN_RS09210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PTUN_RS09215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PTUN_RS09235	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PTUN_RS09240	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PTUN_RS09255	COG3001	Fructosamine kinase
PTUN_RS09265	COG0307	riboflavin synthase, alpha
PTUN_RS09320	COG1620	l-lactate permease
PTUN_RS09340	COG1131	(ABC) transporter
PTUN_RS09345	COG1725	Transcriptional regulator
PTUN_RS09355	COG0513	Belongs to the DEAD box helicase family
PTUN_RS09365	COG5654	RES domain protein
PTUN_RS09375	COG0644	oxidoreductase
PTUN_RS09415	COG1061	Type III restriction enzyme res subunit
PTUN_RS09480	COG0009	L-threonylcarbamoyladenylate synthase
PTUN_RS09490	COG0583	DNA-binding transcription factor activity
PTUN_RS09495	COG2205	protein histidine kinase activity
PTUN_RS09495	COG0784	Response regulator, receiver
PTUN_RS09515	COG0778	Nitroreductase
PTUN_RS09545	COG1288	antiporter activity
PTUN_RS09550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PTUN_RS09565	COG2205	protein histidine kinase activity
PTUN_RS09570	COG0745	RESPONSE REGULATOR receiver
PTUN_RS09575	COG0569	domain protein
PTUN_RS09580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PTUN_RS09605	COG1278	Cold shock
PTUN_RS09610	COG0583	DNA-binding transcription factor activity
PTUN_RS09630	COG0494	nUDIX hydrolase
PTUN_RS09635	COG2828	Protein conserved in bacteria
PTUN_RS09640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PTUN_RS09645	COG0372	Belongs to the citrate synthase family
PTUN_RS09650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PTUN_RS09670	COG2329	Antibiotic biosynthesis monooxygenase
PTUN_RS09695	COG1695	Transcriptional regulator
PTUN_RS09715	COG4628	conserved protein (DUF2132)
PTUN_RS09725	COG3590	peptidase
PTUN_RS09790	COG2200	EAL domain
PTUN_RS09790	COG2199	diguanylate cyclase activity
PTUN_RS09790	COG3287	FIST C domain
PTUN_RS09865	COG0583	DNA-binding transcription factor activity
PTUN_RS09890	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PTUN_RS09915	COG0745	RESPONSE REGULATOR receiver
PTUN_RS09935	COG4104	PAAR repeat-containing protein
PTUN_RS09955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PTUN_RS09955	COG4191	Histidine kinase
PTUN_RS09960	COG2203	Gaf domain
PTUN_RS09960	COG3706	GGDEF domain
PTUN_RS09960	COG4251	negative regulation of phosphorylation
PTUN_RS09960	COG5001	Diguanylate cyclase
PTUN_RS09975	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PTUN_RS09990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PTUN_RS10010	COG0583	DNA-binding transcription factor activity
PTUN_RS10075	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PTUN_RS10080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PTUN_RS10095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PTUN_RS10110	COG4771	TonB-dependent receptor
PTUN_RS10155	COG0840	transmembrane signaling receptor activity
PTUN_RS10170	COG1476	TRANSCRIPTIONal
PTUN_RS10185	COG5507	3-demethylubiquinone-9 3-methyltransferase
PTUN_RS10195	COG1506	peptidase
PTUN_RS10205	COG3547	Transposase (IS116 IS110 IS902 family)
PTUN_RS10285	COG0488	(ABC) transporter
PTUN_RS10310	COG1136	(ABC) transporter
PTUN_RS10360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PTUN_RS10380	COG0583	DNA-binding transcription factor activity
PTUN_RS10390	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PTUN_RS10405	COG0415	Belongs to the DNA photolyase family
PTUN_RS10410	COG3046	protein related to deoxyribodipyrimidine photolyase
PTUN_RS10425	COG2715	membrane protein required for spore maturation
PTUN_RS10430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PTUN_RS10430	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PTUN_RS10440	COG0084	hydrolase, TatD family'
PTUN_RS10455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PTUN_RS10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PTUN_RS10470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PTUN_RS10475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PTUN_RS10485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PTUN_RS10490	COG0416	fatty acid biosynthetic process
PTUN_RS10495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PTUN_RS10500	COG1399	metal-binding, possibly nucleic acid-binding protein
PTUN_RS10505	COG0424	maF-like protein
PTUN_RS10510	COG0546	phosphoglycolate phosphatase activity
PTUN_RS10515	COG0564	pseudouridine synthase activity
PTUN_RS10520	COG1530	ribonuclease E activity
PTUN_RS10525	COG3081	Nucleoid-associated protein
PTUN_RS10530	COG3082	Protein of unknown function (DUF1414)
PTUN_RS10535	COG3083	sulfuric ester hydrolase activity
PTUN_RS10555	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PTUN_RS10575	COG1940	carbohydrate kinase activity
PTUN_RS10585	COG0662	Cupin 2, conserved barrel domain protein
PTUN_RS10585	COG2207	Transcriptional regulator
PTUN_RS10595	COG3023	N-Acetylmuramoyl-L-alanine amidase
PTUN_RS10605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PTUN_RS10615	COG1984	allophanate hydrolase subunit 2
PTUN_RS10625	COG0513	Belongs to the DEAD box helicase family
PTUN_RS10645	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PTUN_RS10665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PTUN_RS10675	COG0217	transcriptional regulatory protein
PTUN_RS10690	COG1376	ErfK ybiS ycfS ynhG family protein
PTUN_RS10700	COG3123	guanosine phosphorylase activity
PTUN_RS10715	COG3278	Belongs to the heme-copper respiratory oxidase family
PTUN_RS10730	COG2010	Cytochrome c
PTUN_RS10740	COG2608	mercury ion transmembrane transporter activity
PTUN_RS10740	COG2217	Heavy metal translocating P-type atpase
PTUN_RS10755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PTUN_RS10760	COG0589	response to stress
PTUN_RS10765	COG0037	tRNA processing
PTUN_RS10785	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PTUN_RS10920	COG3459	Glycosyltransferase 36 associated
PTUN_RS10935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PTUN_RS10940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PTUN_RS10960	COG1733	regulation of RNA biosynthetic process
PTUN_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS10980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PTUN_RS11005	COG1597	lipid kinase activity
PTUN_RS11015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PTUN_RS11020	COG4181	ATPase activity
PTUN_RS11055	COG1227	inorganic diphosphatase activity
PTUN_RS11070	COG0564	pseudouridine synthase activity
PTUN_RS11075	COG0242	peptide deformylase activity
PTUN_RS11095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PTUN_RS11125	COG0583	DNA-binding transcription factor activity
PTUN_RS11130	COG2910	NAD(P)H-binding
PTUN_RS11135	COG1609	Transcriptional regulator
PTUN_RS11160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PTUN_RS11165	COG0840	transmembrane signaling receptor activity
PTUN_RS11220	COG3344	reverse transcriptase
PTUN_RS11265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PTUN_RS11275	COG3139	Protein of unknown function (DUF1315)
PTUN_RS11285	COG1115	amino acid carrier protein
PTUN_RS11290	COG2866	Carboxypeptidase
PTUN_RS11310	COG0776	regulation of translation
PTUN_RS11315	COG0072	phenylalanine-tRNA ligase activity
PTUN_RS11320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PTUN_RS11405	COG0322	excinuclease ABC activity
PTUN_RS11410	COG2197	response regulator
PTUN_RS11415	COG1823	symporter activity
PTUN_RS11420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PTUN_RS11425	COG0583	DNA-binding transcription factor activity
PTUN_RS11435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PTUN_RS11445	COG2084	Dehydrogenase
PTUN_RS11450	COG0386	Belongs to the glutathione peroxidase family
PTUN_RS11455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PTUN_RS11460	COG0733	neurotransmitter:sodium symporter activity
PTUN_RS11470	COG0527	aspartate kinase activity
PTUN_RS11475	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PTUN_RS11505	COG0418	dihydroorotase activity
PTUN_RS11510	COG5001	Diguanylate cyclase
PTUN_RS11510	COG3300	MHYT domain
PTUN_RS11520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PTUN_RS11545	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PTUN_RS11550	COG2885	chlorophyll binding
PTUN_RS11555	COG0823	Involved in the tonB-independent uptake of proteins
PTUN_RS11570	COG0811	peptide transport
PTUN_RS11575	COG2255	four-way junction helicase activity
PTUN_RS11580	COG0632	four-way junction helicase activity
PTUN_RS11585	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PTUN_RS11590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PTUN_RS11595	COG1801	Protein of unknown function DUF72
PTUN_RS11600	COG1451	nucleotide metabolic process
PTUN_RS11610	COG2226	methyltransferase
PTUN_RS11615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PTUN_RS11620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PTUN_RS11625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PTUN_RS11635	COG0121	glutamine amidotransferase
PTUN_RS11640	COG1960	acyl-CoA dehydrogenase activity
PTUN_RS11650	COG1131	(ABC) transporter
PTUN_RS11700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PTUN_RS11715	COG2226	methyltransferase
PTUN_RS11720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PTUN_RS11725	COG0741	lytic transglycosylase activity
PTUN_RS11725	COG1388	LysM domain
PTUN_RS11735	COG0564	pseudouridine synthase activity
PTUN_RS11740	COG3098	single-species biofilm formation
PTUN_RS11770	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PTUN_RS11780	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PTUN_RS11780	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PTUN_RS11795	COG2911	Protein conserved in bacteria
PTUN_RS11800	COG0729	surface antigen
PTUN_RS11810	COG1061	Type III restriction enzyme res subunit
PTUN_RS11830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PTUN_RS11845	COG1757	Na H antiporter
PTUN_RS11850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PTUN_RS11865	COG1566	PFAM secretion protein HlyD family protein
PTUN_RS11880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PTUN_RS11885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PTUN_RS11890	COG0505	Belongs to the CarA family
PTUN_RS11895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PTUN_RS11900	COG1757	Na H antiporter
PTUN_RS11910	COG2814	Major facilitator Superfamily
PTUN_RS11915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PTUN_RS11920	COG1420	regulation of RNA biosynthetic process
PTUN_RS11925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PTUN_RS11935	COG0497	DNA recombination
PTUN_RS11940	COG0493	'glutamate synthase
PTUN_RS11945	COG0069	glutamate synthase activity
PTUN_RS11945	COG0067	glutamate synthase
PTUN_RS11945	COG0070	glutamate synthase
PTUN_RS11955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PTUN_RS11960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PTUN_RS11965	COG2766	serine protein kinase
PTUN_RS11970	COG2718	Belongs to the UPF0229 family
PTUN_RS11975	COG2719	SpoVR family
PTUN_RS11980	COG0589	response to stress
PTUN_RS11985	COG3706	GGDEF domain
PTUN_RS11990	COG2201	protein-glutamate methylesterase activity
PTUN_RS11995	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PTUN_RS12000	COG0563	adenylate kinase activity
PTUN_RS12005	COG0326	Molecular chaperone. Has ATPase activity
PTUN_RS12010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PTUN_RS12015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PTUN_RS12025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PTUN_RS12035	COG3220	belongs to the UPF0276 family
PTUN_RS12045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PTUN_RS12075	COG0848	biopolymer transport protein
PTUN_RS12080	COG0811	peptide transport
PTUN_RS12085	COG0811	peptide transport
PTUN_RS12100	COG0457	Tetratricopeptide repeat
PTUN_RS12105	COG4771	TonB-dependent receptor
PTUN_RS12110	COG0417	DNA replication proofreading
PTUN_RS12115	COG0457	Tetratricopeptide repeat
PTUN_RS12120	COG1199	ATP-dependent helicase activity
PTUN_RS12125	COG0730	response to heat
PTUN_RS12135	COG0123	including yeast histone deacetylase and acetoin utilization protein
PTUN_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS12210	COG0488	(ABC) transporter
PTUN_RS12240	COG0574	Belongs to the PEP-utilizing enzyme family
PTUN_RS12240	COG3848	Pyruvate phosphate dikinase
PTUN_RS12255	COG1136	(ABC) transporter
PTUN_RS12260	COG4591	ABC-type transport system involved in lipoprotein release permease component
PTUN_RS12265	COG1136	(ABC) transporter
PTUN_RS12265	COG0577	efflux transmembrane transporter activity
PTUN_RS12275	COG0778	Nitroreductase
PTUN_RS12280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PTUN_RS12285	COG1960	acyl-CoA dehydrogenase activity
PTUN_RS12295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PTUN_RS12300	COG0156	8-amino-7-oxononanoate synthase activity
PTUN_RS12310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PTUN_RS12315	COG0318	PFAM AMP-dependent synthetase and ligase
PTUN_RS12330	COG3279	Response regulator of the LytR AlgR family
PTUN_RS12340	COG1131	(ABC) transporter
PTUN_RS12365	COG4942	peptidase
PTUN_RS12415	COG3706	GGDEF domain
PTUN_RS12425	COG0037	tRNA processing
PTUN_RS12430	COG0825	malonyl-CoA metabolic process
PTUN_RS12435	COG0587	DNA-directed DNA polymerase activity
PTUN_RS12440	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PTUN_RS12445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PTUN_RS12450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PTUN_RS12455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PTUN_RS12460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PTUN_RS12475	COG0750	zinc metalloprotease
PTUN_RS12480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PTUN_RS12485	COG0575	Belongs to the CDS family
PTUN_RS12490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PTUN_RS12495	COG0233	cytoplasmic translational termination
PTUN_RS12500	COG0528	UMP kinase activity
PTUN_RS12505	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PTUN_RS12510	COG0052	Belongs to the universal ribosomal protein uS2 family
PTUN_RS12515	COG0024	Methionine aminopeptidase
PTUN_RS12520	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PTUN_RS12525	COG2171	N-acyltransferase activity
PTUN_RS12535	COG2918	glutathione biosynthetic process
PTUN_RS12550	COG0542	response to heat
PTUN_RS12565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PTUN_RS12570	COG0347	Belongs to the P(II) protein family
PTUN_RS12615	COG3275	phosphorelay sensor kinase activity
PTUN_RS12620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PTUN_RS12625	COG1047	Peptidyl-prolyl cis-trans
PTUN_RS12630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PTUN_RS12635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PTUN_RS12640	COG0196	riboflavin kinase activity
PTUN_RS12645	COG0728	peptidoglycan biosynthetic process
PTUN_RS12650	COG0268	Binds directly to 16S ribosomal RNA
PTUN_RS12655	COG2201	protein-glutamate methylesterase activity
PTUN_RS12695	COG3047	cAMP biosynthetic process
PTUN_RS12715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PTUN_RS12720	COG1215	transferase activity, transferring glycosyl groups
PTUN_RS12785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PTUN_RS12790	COG3267	Type II secretory pathway component ExeA
PTUN_RS12790	COG3409	Peptidoglycan-binding domain 1 protein
PTUN_RS12805	COG5265	(ABC) transporter
PTUN_RS12815	COG3104	oligopeptide transport
PTUN_RS12840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PTUN_RS12845	COG2814	Major facilitator Superfamily
PTUN_RS12855	COG1803	Methylglyoxal synthase
PTUN_RS12860	COG0612	Peptidase, M16
PTUN_RS12865	COG2062	phosphohistidine phosphatase, SixA
PTUN_RS12870	COG1025	Belongs to the peptidase M16 family
PTUN_RS12885	COG1024	Enoyl-CoA hydratase
PTUN_RS12885	COG1250	3-hydroxyacyl-CoA dehydrogenase
PTUN_RS12890	COG0183	Belongs to the thiolase family
PTUN_RS12900	COG0714	Associated with various cellular activities
PTUN_RS12920	COG2304	oxidoreductase activity
PTUN_RS12930	COG1595	DNA-templated transcription, initiation
PTUN_RS12945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PTUN_RS12950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PTUN_RS12975	COG1138	Cytochrome C-type biogenesis protein
PTUN_RS12980	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PTUN_RS12985	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PTUN_RS12990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PTUN_RS12995	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PTUN_RS13020	COG0835	chemotaxis
PTUN_RS13030	COG1192	Involved in chromosome partitioning
PTUN_RS13035	COG1360	Flagellar Motor Protein
PTUN_RS13040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PTUN_RS13045	COG2201	protein-glutamate methylesterase activity
PTUN_RS13050	COG2198	Histidine kinase
PTUN_RS13050	COG0784	Response regulator, receiver
PTUN_RS13050	COG0643	Histidine kinase
PTUN_RS13055	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PTUN_RS13080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PTUN_RS13085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PTUN_RS13090	COG1684	flagellar biosynthetic protein fliR
PTUN_RS13095	COG1987	bacterial-type flagellum assembly
PTUN_RS13125	COG3144	bacterial-type flagellum assembly
PTUN_RS13145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PTUN_RS13175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PTUN_RS13180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PTUN_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS13210	COG1083	cytidylyl-transferase
PTUN_RS13225	COG2226	methyltransferase
PTUN_RS13240	COG2089	acid synthase
PTUN_RS13245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PTUN_RS13250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PTUN_RS13255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PTUN_RS13270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PTUN_RS13275	COG1334	flagellar protein FlaG
PTUN_RS13295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PTUN_RS13305	COG3951	Flagellar rod assembly protein muramidase FlgJ
PTUN_RS13305	COG1705	Flagellar rod assembly protein muramidase FlgJ
PTUN_RS13310	COG1706	bacterial-type flagellum-dependent cell motility
PTUN_RS13315	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PTUN_RS13320	COG4786	Flagellar basal body rod
PTUN_RS13325	COG4786	Flagellar basal body rod
PTUN_RS13340	COG1558	bacterial-type flagellum-dependent cell motility
PTUN_RS13345	COG1815	bacterial-type flagellum-dependent cell motility
PTUN_RS13350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PTUN_RS13355	COG0784	Response regulator, receiver
PTUN_RS13355	COG0835	chemotaxis
PTUN_RS13385	COG0678	peroxiredoxin activity
PTUN_RS13385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PTUN_RS13450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PTUN_RS13455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PTUN_RS13460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PTUN_RS13465	COG0730	response to heat
PTUN_RS13475	COG1051	belongs to the nudix hydrolase family
PTUN_RS13480	COG3066	DNA modification
PTUN_RS13485	COG0148	phosphopyruvate hydratase activity
PTUN_RS13490	COG0504	CTP synthase activity
PTUN_RS13495	COG3956	TIGRFAM MazG family protein
PTUN_RS13500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PTUN_RS13505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PTUN_RS13510	COG3437	response regulator, receiver
PTUN_RS13510	COG3850	Histidine kinase
PTUN_RS13510	COG4999	Histidine kinase
PTUN_RS13510	COG2205	protein histidine kinase activity
PTUN_RS13515	COG0564	pseudouridine synthase activity
PTUN_RS13540	COG0784	Response regulator, receiver
PTUN_RS13540	COG2205	protein histidine kinase activity
PTUN_RS13550	COG0840	transmembrane signaling receptor activity
PTUN_RS13555	COG0754	glutathionylspermidine amidase activity
PTUN_RS13570	COG0513	Belongs to the DEAD box helicase family
PTUN_RS13575	COG0583	DNA-binding transcription factor activity
PTUN_RS13610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PTUN_RS13615	COG1381	Involved in DNA repair and RecF pathway recombination
PTUN_RS13625	COG0571	ribonuclease III activity
PTUN_RS13635	COG0481	GTPase activity
PTUN_RS13650	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
PTUN_RS13655	COG1595	DNA-templated transcription, initiation
PTUN_RS13660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PTUN_RS13670	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PTUN_RS13680	COG1047	Peptidyl-prolyl cis-trans
PTUN_RS13685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PTUN_RS13690	COG0739	heme binding
PTUN_RS13695	COG3022	response to hydroperoxide
PTUN_RS13700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PTUN_RS13705	COG0166	Belongs to the GPI family
PTUN_RS13715	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PTUN_RS13720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PTUN_RS13740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PTUN_RS13740	COG4191	Histidine kinase
PTUN_RS13745	COG2974	May be involved in recombination
PTUN_RS13770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PTUN_RS13780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PTUN_RS13790	COG1477	protein flavinylation
PTUN_RS13795	COG2871	sodium ion transport
PTUN_RS13800	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PTUN_RS13805	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PTUN_RS13815	COG1805	sodium ion transport
PTUN_RS13820	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PTUN_RS13825	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PTUN_RS13830	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PTUN_RS13845	COG0271	Belongs to the BolA IbaG family
PTUN_RS13855	COG2813	Specifically methylates the guanine in position
PTUN_RS13865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PTUN_RS13870	COG2211	Major facilitator Superfamily
PTUN_RS13890	COG0316	Belongs to the HesB IscA family
PTUN_RS13905	COG1981	membrane
PTUN_RS13910	COG0540	Belongs to the ATCase OTCase family
PTUN_RS13915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PTUN_RS13920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PTUN_RS13930	COG0667	Aldo Keto reductase
PTUN_RS13935	COG3279	Response regulator of the LytR AlgR family
PTUN_RS13955	COG1643	Atp-dependent helicase
PTUN_RS13960	COG0004	ammonium transporteR
PTUN_RS13970	COG3275	phosphorelay sensor kinase activity
PTUN_RS13980	COG3275	phosphorelay sensor kinase activity
PTUN_RS13985	COG3279	Response regulator of the LytR AlgR family
PTUN_RS14010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PTUN_RS14015	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PTUN_RS14020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PTUN_RS14025	COG1944	ATP diphosphatase activity
PTUN_RS14030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PTUN_RS14040	COG0560	Phosphoserine phosphatase
PTUN_RS14050	COG0084	hydrolase, TatD family'
PTUN_RS14055	COG0259	pyridoxamine-phosphate oxidase activity
PTUN_RS14060	COG0018	arginyl-trna synthetase
PTUN_RS14065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PTUN_RS14080	COG2205	protein histidine kinase activity
PTUN_RS14080	COG0784	Response regulator, receiver
PTUN_RS14085	COG0456	acetyltransferase
PTUN_RS14105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PTUN_RS14105	COG0519	Catalyzes the synthesis of GMP from XMP
PTUN_RS14110	COG0517	IMP dehydrogenase activity
PTUN_RS14110	COG0516	GMP reductase activity
PTUN_RS14115	COG1570	exodeoxyribonuclease VII activity
PTUN_RS14125	COG3397	chitin binding
PTUN_RS14140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PTUN_RS14150	COG1388	LysM domain
PTUN_RS14150	COG4942	peptidase
PTUN_RS14155	COG1238	metal cluster binding
PTUN_RS14160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PTUN_RS14165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PTUN_RS14170	COG0585	pseudouridine synthase activity
PTUN_RS14175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PTUN_RS14180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PTUN_RS14185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PTUN_RS14210	COG3283	Transcriptional regulator of aromatic amino acids metabolism
PTUN_RS14250	COG4067	protein conserved in archaea
PTUN_RS14250	COG0189	ligase activity
PTUN_RS14255	COG0189	ligase activity
PTUN_RS14260	COG4771	TonB-dependent receptor
PTUN_RS14270	COG0069	glutamate synthase activity
PTUN_RS14275	COG0513	Belongs to the DEAD box helicase family
PTUN_RS14285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PTUN_RS14305	COG0583	DNA-binding transcription factor activity
PTUN_RS14320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PTUN_RS14325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PTUN_RS14330	COG0697	spore germination
PTUN_RS14350	COG0745	RESPONSE REGULATOR receiver
PTUN_RS14355	COG2205	protein histidine kinase activity
PTUN_RS14360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PTUN_RS14385	COG4413	Urea transporter
PTUN_RS14390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PTUN_RS14395	COG1489	DNA binding
PTUN_RS14405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PTUN_RS14415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PTUN_RS14420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PTUN_RS14425	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PTUN_RS14440	COG5002	protein histidine kinase activity
PTUN_RS14445	COG0745	RESPONSE REGULATOR receiver
PTUN_RS14470	COG0126	phosphoglycerate kinase activity
PTUN_RS14475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PTUN_RS14480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PTUN_RS14485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PTUN_RS14495	COG3025	triphosphatase activity
PTUN_RS14500	COG4991	sh3 domain protein
PTUN_RS14515	COG3437	response regulator, receiver
PTUN_RS14515	COG0784	Response regulator, receiver
PTUN_RS14530	COG3267	Type II secretory pathway component ExeA
PTUN_RS14530	COG3409	Peptidoglycan-binding domain 1 protein
PTUN_RS14545	COG0681	Belongs to the peptidase S26 family
PTUN_RS14550	COG1968	undecaprenyl-diphosphatase activity
PTUN_RS14555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PTUN_RS14565	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PTUN_RS14570	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PTUN_RS14575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PTUN_RS14595	COG2264	protein methyltransferase activity
PTUN_RS14600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PTUN_RS14605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PTUN_RS14610	COG0138	bifunctional purine biosynthesis protein purh
PTUN_RS14620	COG0151	Belongs to the GarS family
PTUN_RS14650	COG0745	RESPONSE REGULATOR receiver
PTUN_RS14655	COG2205	protein histidine kinase activity
PTUN_RS14660	COG2267	carboxylic ester hydrolase activity
PTUN_RS14670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PTUN_RS14675	COG3300	MHYT domain
PTUN_RS14675	COG5001	Diguanylate cyclase
PTUN_RS14680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PTUN_RS14685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PTUN_RS14690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PTUN_RS14695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PTUN_RS14700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PTUN_RS14705	COG4942	peptidase
PTUN_RS14710	COG0793	Belongs to the peptidase S41A family
PTUN_RS14725	COG2177	Part of the ABC transporter FtsEX involved in
PTUN_RS14730	COG2884	Cell division ATP-binding protein ftsE
PTUN_RS14735	COG0552	protein localization to endoplasmic reticulum
PTUN_RS14740	COG0742	ribosomal rna small subunit methyltransferase
PTUN_RS14745	COG3068	Protein conserved in bacteria
PTUN_RS14765	COG3437	response regulator, receiver
PTUN_RS14765	COG0784	Response regulator, receiver
PTUN_RS14770	COG0583	DNA-binding transcription factor activity
PTUN_RS14780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PTUN_RS14785	COG3161	chorismate lyase activity
PTUN_RS14790	COG1580	Controls the rotational direction of flagella during chemotaxis
PTUN_RS14800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PTUN_RS14805	COG1063	alcohol dehydrogenase
PTUN_RS14820	COG0859	PFAM glycosyl transferase family 9
PTUN_RS14825	COG3642	lipopolysaccharide core region biosynthetic process
PTUN_RS14830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PTUN_RS14830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PTUN_RS14835	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PTUN_RS14845	COG1519	Transferase
PTUN_RS14855	COG0189	ligase activity
PTUN_RS14870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PTUN_RS14885	COG2801	Transposase and inactivated derivatives
PTUN_RS14900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PTUN_RS14900	COG0165	Argininosuccinate lyase
PTUN_RS14905	COG0137	argininosuccinate synthase activity
PTUN_RS14915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PTUN_RS14920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PTUN_RS14935	COG1160	GTP binding
PTUN_RS14940	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PTUN_RS14945	COG2976	Protein conserved in bacteria
PTUN_RS14950	COG0124	histidyl-tRNA synthetase
PTUN_RS14955	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PTUN_RS14960	COG1426	Protein conserved in bacteria
PTUN_RS14970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PTUN_RS14975	COG0105	UTP biosynthetic process
PTUN_RS14980	COG0826	peptidase U32
PTUN_RS14985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PTUN_RS14990	COG1368	sulfuric ester hydrolase activity
PTUN_RS15005	COG1012	belongs to the aldehyde dehydrogenase family
PTUN_RS15015	COG0443	Heat shock 70 kDa protein
PTUN_RS15025	COG0316	Belongs to the HesB IscA family
PTUN_RS15030	COG0822	iron-sulfur transferase activity
PTUN_RS15035	COG1104	cysteine desulfurase activity
PTUN_RS15045	COG1045	serine acetyltransferase
PTUN_RS15050	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PTUN_RS15095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PTUN_RS15100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PTUN_RS15105	COG1862	Preprotein translocase
PTUN_RS15110	COG0343	queuine tRNA-ribosyltransferase activity
PTUN_RS15115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PTUN_RS15120	COG5002	protein histidine kinase activity
PTUN_RS15120	COG5001	Diguanylate cyclase
PTUN_RS15140	COG1595	DNA-templated transcription, initiation
PTUN_RS15150	COG0583	DNA-binding transcription factor activity
PTUN_RS15155	COG0306	phosphate transporter
PTUN_RS15160	COG1392	Phosphate transport regulator
PTUN_RS15170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PTUN_RS15175	COG0581	inorganic phosphate transmembrane transporter activity
PTUN_RS15190	COG0076	glutamate decarboxylase activity
PTUN_RS15195	COG3287	FIST C domain
PTUN_RS15195	COG2200	EAL domain
PTUN_RS15195	COG2199	diguanylate cyclase activity
PTUN_RS15200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PTUN_RS15205	COG0842	Transport permease protein
PTUN_RS15210	COG1131	(ABC) transporter
PTUN_RS15215	COG0163	prenyltransferase activity
PTUN_RS15220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PTUN_RS15230	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PTUN_RS15245	COG1309	transcriptional regulator
PTUN_RS15285	COG2897	thiosulfate sulfurtransferase activity
PTUN_RS15290	COG3562	capsule polysaccharide
PTUN_RS15305	COG0745	RESPONSE REGULATOR receiver
PTUN_RS15315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PTUN_RS15320	COG1187	pseudouridine synthase activity
PTUN_RS15325	COG0840	transmembrane signaling receptor activity
PTUN_RS15355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PTUN_RS15360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PTUN_RS15370	COG4206	TonB-dependent receptor
PTUN_RS15375	COG1666	GTP binding
PTUN_RS15390	COG0301	tRNA thio-modification
PTUN_RS15390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PTUN_RS15395	COG0840	transmembrane signaling receptor activity
PTUN_RS15410	COG3038	cytochrome b561
PTUN_RS15415	COG0583	DNA-binding transcription factor activity
PTUN_RS15420	COG0047	phosphoribosylformylglycinamidine synthase activity
PTUN_RS15420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PTUN_RS15425	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PTUN_RS15435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PTUN_RS15455	COG1115	amino acid carrier protein
PTUN_RS15465	COG0745	RESPONSE REGULATOR receiver
PTUN_RS15485	COG0459	protein refolding
PTUN_RS15490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PTUN_RS15500	COG1324	tolerance protein
PTUN_RS15505	COG4232	protein-disulfide reductase activity
PTUN_RS15510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PTUN_RS15515	COG0511	ligase activity, forming carbon-carbon bonds
PTUN_RS15520	COG0439	Biotin carboxylase
PTUN_RS15535	COG0840	transmembrane signaling receptor activity
PTUN_RS15540	COG1247	-acetyltransferase
PTUN_RS15570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PTUN_RS15590	COG3954	Phosphoribulokinase
PTUN_RS15595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PTUN_RS15600	COG1765	OsmC-like protein
PTUN_RS15610	COG1012	belongs to the aldehyde dehydrogenase family
PTUN_RS15615	COG3138	arginine N-succinyltransferase
PTUN_RS15620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PTUN_RS15635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PTUN_RS15650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PTUN_RS15660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PTUN_RS15665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PTUN_RS15695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PTUN_RS15700	COG0460	homoserine dehydrogenase
PTUN_RS15700	COG0527	aspartate kinase activity
PTUN_RS15705	COG0626	cystathionine gamma-synthase activity
PTUN_RS15710	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
PTUN_RS15715	COG0281	malic enzyme
PTUN_RS15730	COG3078	GTPase activator activity
PTUN_RS15735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PTUN_RS15755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PTUN_RS15765	COG1506	peptidase
PTUN_RS15765	COG0823	Involved in the tonB-independent uptake of proteins
PTUN_RS15780	COG0606	chelatase, subunit chli
PTUN_RS15795	COG2860	membrane
PTUN_RS15820	COG0066	3-isopropylmalate dehydratase activity
PTUN_RS15825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PTUN_RS15830	COG0473	3-isopropylmalate dehydrogenase activity
PTUN_RS15835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PTUN_RS15870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PTUN_RS15875	COG0348	domain, Protein
PTUN_RS15920	COG2165	general secretion pathway protein
PTUN_RS15930	COG2165	general secretion pathway protein
PTUN_RS15935	COG1459	type II secretion system
PTUN_RS15940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PTUN_RS15950	COG3031	protein transport across the cell outer membrane
PTUN_RS15960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PTUN_RS15965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PTUN_RS15980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PTUN_RS15985	COG2183	response to ionizing radiation
PTUN_RS16000	COG0596	Alpha beta hydrolase
PTUN_RS16005	COG1040	competence protein
PTUN_RS16015	COG0316	Belongs to the HesB IscA family
PTUN_RS16015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PTUN_RS16025	COG0534	Mate efflux family protein
PTUN_RS16030	COG0726	polysaccharide deacetylase
PTUN_RS16040	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PTUN_RS16045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PTUN_RS16050	COG0840	transmembrane signaling receptor activity
PTUN_RS16055	COG0835	chemotaxis
PTUN_RS16060	COG2198	Histidine kinase
PTUN_RS16060	COG0643	Histidine kinase
PTUN_RS16065	COG0745	RESPONSE REGULATOR receiver
PTUN_RS16080	COG0109	protoheme IX farnesyltransferase activity
PTUN_RS16110	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PTUN_RS16115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PTUN_RS16125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PTUN_RS16145	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PTUN_RS16150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PTUN_RS16155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PTUN_RS16160	COG1561	YicC-like family, N-terminal region
PTUN_RS16165	COG0194	GDP metabolic process
PTUN_RS16170	COG1758	RNA polymerase activity
PTUN_RS16175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PTUN_RS16195	COG1522	sequence-specific DNA binding
PTUN_RS16200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PTUN_RS16205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PTUN_RS16215	COG0583	DNA-binding transcription factor activity
PTUN_RS16220	COG3085	chromosome segregation
PTUN_RS16225	COG0189	ligase activity
PTUN_RS16235	COG2962	Rard protein
PTUN_RS16240	COG2050	protein possibly involved in aromatic compounds catabolism
PTUN_RS16245	COG0514	ATP-dependent DNA helicase (RecQ)
PTUN_RS16270	COG1131	(ABC) transporter
PTUN_RS16295	COG0024	Methionine aminopeptidase
PTUN_RS16310	COG5479	isomerase activity
PTUN_RS16310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PTUN_RS16315	COG0840	transmembrane signaling receptor activity
PTUN_RS16345	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PTUN_RS16350	COG3842	ATPase activity
PTUN_RS16355	COG1176	ABC-type spermidine putrescine transport system, permease component I
PTUN_RS16360	COG1177	transmembrane transport
PTUN_RS16365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PTUN_RS16370	COG5007	Belongs to the BolA IbaG family
PTUN_RS16375	COG3113	response to antibiotic
PTUN_RS16380	COG2854	intermembrane phospholipid transfer
PTUN_RS16385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PTUN_RS16390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PTUN_RS16395	COG1127	ABC transporter
PTUN_RS16405	COG0517	IMP dehydrogenase activity
PTUN_RS16405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PTUN_RS16410	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PTUN_RS16425	COG1137	ATPase activity
PTUN_RS16430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PTUN_RS16435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PTUN_RS16440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PTUN_RS16445	COG1660	Displays ATPase and GTPase activities
PTUN_RS16450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PTUN_RS16455	COG2239	Acts as a magnesium transporter
PTUN_RS16460	COG0312	modulator of DNA gyrase
PTUN_RS16465	COG3028	Belongs to the UPF0307 family
PTUN_RS16490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PTUN_RS16495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PTUN_RS16500	COG0049	tRNA binding
PTUN_RS16505	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PTUN_RS16510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PTUN_RS16515	COG0085	RNA polymerase activity
PTUN_RS16520	COG0222	ribosome binding
PTUN_RS16525	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PTUN_RS16535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PTUN_RS16540	COG0250	Participates in transcription elongation, termination and antitermination
PTUN_RS16545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PTUN_RS16555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PTUN_RS16560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PTUN_RS16585	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PTUN_RS16595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PTUN_RS16600	COG0308	aminopeptidase N
PTUN_RS16610	COG0537	adenosine 5'-monophosphoramidase activity
PTUN_RS16625	COG3132	Protein of unknown function, DUF480
PTUN_RS16630	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PTUN_RS16635	COG3706	GGDEF domain
PTUN_RS16650	COG0302	gtp cyclohydrolase
PTUN_RS16655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PTUN_RS16660	COG1238	metal cluster binding
PTUN_RS16690	COG5520	Belongs to the glycosyl hydrolase 30 family
PTUN_RS16690	COG4447	cellulose binding
PTUN_RS16690	COG3291	Pkd domain containing protein
PTUN_RS16735	COG1770	oligopeptidase
PTUN_RS16740	COG1404	Belongs to the peptidase S8 family
PTUN_RS16750	COG1404	Belongs to the peptidase S8 family
PTUN_RS16770	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PTUN_RS16780	COG1946	Acyl-CoA thioesterase
PTUN_RS16815	COG3706	GGDEF domain
PTUN_RS16825	COG2226	methyltransferase
PTUN_RS16840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PTUN_RS16845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PTUN_RS16850	COG0805	protein transport
PTUN_RS16900	COG1218	3'(2'),5'-bisphosphate nucleotidase
PTUN_RS16905	COG0494	nUDIX hydrolase
PTUN_RS16910	COG1011	Hydrolase
PTUN_RS17005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PTUN_RS17040	COG2937	Belongs to the GPAT DAPAT family
PTUN_RS17045	COG0386	Belongs to the glutathione peroxidase family
PTUN_RS17060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PTUN_RS17070	COG1597	lipid kinase activity
PTUN_RS17080	COG5002	protein histidine kinase activity
PTUN_RS17085	COG0745	RESPONSE REGULATOR receiver
PTUN_RS17115	COG1025	Belongs to the peptidase M16 family
PTUN_RS17125	COG2354	Protein conserved in bacteria
PTUN_RS17130	COG0840	transmembrane signaling receptor activity
PTUN_RS17145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PTUN_RS17160	COG4191	Histidine kinase
PTUN_RS17165	COG2204	response regulator
PTUN_RS17175	COG1136	(ABC) transporter
PTUN_RS17175	COG0577	efflux transmembrane transporter activity
PTUN_RS17185	COG0513	Belongs to the DEAD box helicase family
PTUN_RS17200	COG0784	Response regulator, receiver
PTUN_RS17200	COG5002	protein histidine kinase activity
PTUN_RS17240	COG0848	biopolymer transport protein
PTUN_RS17245	COG0811	peptide transport
PTUN_RS17250	COG0811	peptide transport
PTUN_RS17260	COG4774	siderophore transport
PTUN_RS17265	COG3128	pkhd-type hydroxylase
PTUN_RS17295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PTUN_RS17305	COG1476	TRANSCRIPTIONal
PTUN_RS17320	COG3397	chitin binding
PTUN_RS17325	COG3408	Glycogen debranching enzyme
PTUN_RS17325	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
PTUN_RS17350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PTUN_RS17375	COG0577	efflux transmembrane transporter activity
PTUN_RS17375	COG1136	(ABC) transporter
PTUN_RS17385	COG2204	response regulator
PTUN_RS17390	COG2205	protein histidine kinase activity
PTUN_RS17415	COG1136	(ABC) transporter
PTUN_RS17415	COG0577	efflux transmembrane transporter activity
PTUN_RS17440	COG2862	Uncharacterized protein family, UPF0114
PTUN_RS17445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PTUN_RS17445	COG4191	Histidine kinase
PTUN_RS17460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PTUN_RS17460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PTUN_RS17475	COG3710	Transcriptional regulator
PTUN_RS17480	COG0676	glucose-6-phosphate 1-epimerase activity
PTUN_RS17485	COG2066	Belongs to the glutaminase family
PTUN_RS17490	COG4191	Histidine kinase
PTUN_RS17490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PTUN_RS17515	COG1309	transcriptional regulator
PTUN_RS17525	COG0745	RESPONSE REGULATOR receiver
PTUN_RS17530	COG2205	protein histidine kinase activity
PTUN_RS17580	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PTUN_RS17600	COG2197	response regulator
PTUN_RS17605	COG4585	Histidine kinase
PTUN_RS17610	COG2267	carboxylic ester hydrolase activity
PTUN_RS17620	COG0513	Belongs to the DEAD box helicase family
PTUN_RS17635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PTUN_RS17640	COG1349	DNA-binding transcription factor activity
PTUN_RS17655	COG0110	maltose O-acetyltransferase activity
PTUN_RS17665	COG0577	efflux transmembrane transporter activity
PTUN_RS17670	COG0577	efflux transmembrane transporter activity
PTUN_RS17675	COG0577	efflux transmembrane transporter activity
PTUN_RS17675	COG1136	(ABC) transporter
PTUN_RS17680	COG1566	PFAM secretion protein HlyD family protein
PTUN_RS17690	COG4191	Histidine kinase
PTUN_RS17720	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PTUN_RS17725	COG0076	glutamate decarboxylase activity
PTUN_RS17745	COG1136	(ABC) transporter
PTUN_RS17845	COG3275	phosphorelay sensor kinase activity
PTUN_RS17850	COG3279	Response regulator of the LytR AlgR family
PTUN_RS17870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PTUN_RS17875	COG0384	phenazine biosynthesis protein PhzF
PTUN_RS17885	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PTUN_RS17890	COG0840	transmembrane signaling receptor activity
PTUN_RS17900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PTUN_RS17905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PTUN_RS17910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PTUN_RS17915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PTUN_RS17920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PTUN_RS17930	COG0356	it plays a direct role in the translocation of protons across the membrane
PTUN_RS17940	COG1475	DNA binding
PTUN_RS17945	COG1192	Involved in chromosome partitioning
PTUN_RS17950	COG0357	Ribosomal RNA small subunit methyltransferase G
PTUN_RS17955	COG0445	tRNA wobble uridine modification
PTUN_RS17960	COG0716	FMN binding
PTUN_RS17970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PTUN_RS17975	COG0706	membrane insertase activity
PTUN_RS17980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PTUN_RS17985	COG0594	ribonuclease P activity
PTUN_RS17990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PTUN_RS17995	COG1192	Involved in chromosome partitioning
PTUN_RS18005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PTUN_RS18010	COG3135	benzoate transporter
PTUN_RS18015	COG1396	sequence-specific DNA binding
PTUN_RS18040	COG4335	DNA alkylation repair
PTUN_RS18080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PTUN_RS18105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PTUN_RS18110	COG0217	transcriptional regulatory protein
PTUN_RS18120	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PTUN_RS18140	COG0625	glutathione transferase activity
PTUN_RS18175	COG1879	ABC-type sugar transport system periplasmic component
PTUN_RS18180	COG1172	Belongs to the binding-protein-dependent transport system permease family
PTUN_RS18205	COG1082	Xylose isomerase domain protein TIM barrel
PTUN_RS18225	COG3344	reverse transcriptase
PTUN_RS18240	COG1129	ABC transporter
PTUN_RS18270	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PTUN_RS18290	COG1595	DNA-templated transcription, initiation
PTUN_RS18300	COG0784	Response regulator, receiver
PTUN_RS18300	COG2205	protein histidine kinase activity
PTUN_RS18305	COG0488	(ABC) transporter
PTUN_RS18315	COG0564	pseudouridine synthase activity
PTUN_RS18325	COG4191	Histidine kinase
PTUN_RS18330	COG0840	transmembrane signaling receptor activity
PTUN_RS18340	COG0583	DNA-binding transcription factor activity
PTUN_RS18350	COG1979	alcohol dehydrogenase
PTUN_RS18355	COG2130	NADP-dependent
PTUN_RS18405	COG4771	TonB-dependent receptor
PTUN_RS18415	COG5654	RES domain protein
PTUN_RS18420	COG5642	Protein of unknown function (DUF2384)
PTUN_RS18425	COG1283	sodium-dependent phosphate transmembrane transporter activity
PTUN_RS18445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PTUN_RS18450	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PTUN_RS18490	COG1278	Cold shock
PTUN_RS18495	COG1278	Cold shock
PTUN_RS18500	COG0557	exoribonuclease II activity
PTUN_RS18505	COG1404	Belongs to the peptidase S8 family
PTUN_RS18520	COG0823	Involved in the tonB-independent uptake of proteins
PTUN_RS18520	COG1506	peptidase
PTUN_RS18520	COG4946	Tricorn protease homolog
PTUN_RS18600	COG1477	protein flavinylation
PTUN_RS18625	COG1435	thymidine kinase activity
PTUN_RS18640	COG0346	lactoylglutathione lyase activity
PTUN_RS18645	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PTUN_RS18655	COG0457	Tetratricopeptide repeat
PTUN_RS18660	COG4771	TonB-dependent receptor
PTUN_RS18675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PTUN_RS18680	COG0393	Putative heavy-metal-binding
PTUN_RS18695	COG1858	cytochrome C peroxidase
PTUN_RS18705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PTUN_RS18730	COG3344	reverse transcriptase
PTUN_RS18805	COG0577	efflux transmembrane transporter activity
PTUN_RS18805	COG1136	(ABC) transporter
PTUN_RS18815	COG2204	response regulator
PTUN_RS18820	COG4191	Histidine kinase
PTUN_RS18845	COG0583	DNA-binding transcription factor activity
PTUN_RS18870	COG4774	siderophore transport
PTUN_RS18870	COG1629	transport
PTUN_RS18920	COG1234	tRNA 3'-trailer cleavage
PTUN_RS18925	COG4771	TonB-dependent receptor
PTUN_RS18935	COG0189	ligase activity
PTUN_RS18970	COG0076	glutamate decarboxylase activity
PTUN_RS18995	COG4615	Cyclic peptide transporter
PTUN_RS19045	COG2304	oxidoreductase activity
PTUN_RS19050	COG1595	DNA-templated transcription, initiation
PTUN_RS19060	COG3104	oligopeptide transport
PTUN_RS19075	COG3118	belongs to the thioredoxin family
PTUN_RS19125	COG3291	Pkd domain containing protein
PTUN_RS19155	COG3547	Transposase (IS116 IS110 IS902 family)
PTUN_RS19180	COG2801	Transposase and inactivated derivatives
PTUN_RS19195	COG3850	Histidine kinase
PTUN_RS19195	COG2205	protein histidine kinase activity
PTUN_RS19195	COG3437	response regulator, receiver
PTUN_RS19195	COG4999	Histidine kinase
PTUN_RS19215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PTUN_RS19230	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PTUN_RS19275	COG1404	Belongs to the peptidase S8 family
PTUN_RS19290	COG1881	PFAM PEBP family protein
PTUN_RS19315	COG3040	lipid binding
PTUN_RS19340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PTUN_RS19365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PTUN_RS19375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PTUN_RS19380	COG0251	oxidation-reduction process
PTUN_RS19385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PTUN_RS19400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PTUN_RS19420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PTUN_RS19425	COG1228	amidohydrolase
PTUN_RS19440	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PTUN_RS19465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PTUN_RS19495	COG2268	Band 7 protein
PTUN_RS19510	COG0189	ligase activity
PTUN_RS19545	COG1280	lysine exporter protein (LysE YggA)
PTUN_RS19560	COG1609	Transcriptional regulator
PTUN_RS19565	COG2211	Major facilitator Superfamily
PTUN_RS19580	COG1472	Belongs to the glycosyl hydrolase 3 family
PTUN_RS19585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PTUN_RS19630	COG0753	catalase activity
PTUN_RS19635	COG1846	Transcriptional regulator
PTUN_RS19640	COG1764	response to oxidative stress
PTUN_RS19650	COG0745	RESPONSE REGULATOR receiver
PTUN_RS19665	COG1028	Short-chain dehydrogenase reductase Sdr
PTUN_RS19670	COG0741	lytic transglycosylase activity
PTUN_RS19695	COG0420	3'-5' exonuclease activity
PTUN_RS19700	COG0419	ATPase involved in DNA repair
PTUN_RS19730	COG2201	protein-glutamate methylesterase activity
PTUN_RS19740	COG5002	protein histidine kinase activity
PTUN_RS19740	COG0784	Response regulator, receiver
PTUN_RS19740	COG2205	protein histidine kinase activity
PTUN_RS19750	COG1294	oxidase, subunit
PTUN_RS19755	COG1271	oxidase subunit
PTUN_RS19775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PTUN_RS19795	COG0745	RESPONSE REGULATOR receiver
PTUN_RS19810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PTUN_RS19825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PTUN_RS19855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PTUN_RS19860	COG0545	Peptidyl-prolyl cis-trans isomerase
PTUN_RS19865	COG1902	pentaerythritol trinitrate reductase activity
PTUN_RS19870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PTUN_RS19875	COG1671	Belongs to the UPF0178 family
PTUN_RS19880	COG1278	Cold shock
PTUN_RS19890	COG0784	Response regulator, receiver
PTUN_RS19890	COG5002	protein histidine kinase activity
PTUN_RS19895	COG0813	purine-nucleoside phosphorylase activity
PTUN_RS19900	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PTUN_RS19910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PTUN_RS19935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PTUN_RS19950	COG4628	conserved protein (DUF2132)
PTUN_RS19990	COG0737	Belongs to the 5'-nucleotidase family
PTUN_RS20050	COG3547	Transposase (IS116 IS110 IS902 family)
PTUN_RS20075	COG0625	glutathione transferase activity
PTUN_RS20080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PTUN_RS20115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PTUN_RS20135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PTUN_RS20140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PTUN_RS20145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PTUN_RS20160	COG1136	(ABC) transporter
PTUN_RS20160	COG0577	efflux transmembrane transporter activity
PTUN_RS20165	COG2204	response regulator
PTUN_RS20170	COG4191	Histidine kinase
PTUN_RS20175	COG0653	protein targeting
PTUN_RS20180	COG2205	protein histidine kinase activity
PTUN_RS20185	COG0745	RESPONSE REGULATOR receiver
PTUN_RS20195	COG0534	Mate efflux family protein
PTUN_RS20200	COG0814	amino acid
PTUN_RS20215	COG3008	intermembrane lipid transfer
PTUN_RS20215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PTUN_RS20220	COG2995	paraquat-inducible protein a
PTUN_RS20230	COG1454	alcohol dehydrogenase
PTUN_RS20265	COG1609	Transcriptional regulator
PTUN_RS20285	COG0328	RNA-DNA hybrid ribonuclease activity
PTUN_RS20305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PTUN_RS20310	COG0006	proline dipeptidase activity
PTUN_RS20330	COG2194	sulfuric ester hydrolase activity
PTUN_RS20355	COG5001	Diguanylate cyclase
PTUN_RS20355	COG3300	MHYT domain
PTUN_RS20390	COG0457	Tetratricopeptide repeat
PTUN_RS20420	COG3038	cytochrome b561
PTUN_RS20425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PTUN_RS20455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PTUN_RS20475	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PTUN_RS20480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PTUN_RS20490	COG0295	cytidine deaminase activity
PTUN_RS20500	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
PTUN_RS20510	COG1022	Amp-dependent synthetase and ligase
PTUN_RS20530	COG0745	RESPONSE REGULATOR receiver
PTUN_RS20540	COG4633	Protein conserved in bacteria
PTUN_RS20560	COG1438	arginine binding
PTUN_RS20585	COG0443	Heat shock 70 kDa protein
PTUN_RS20590	COG0484	heat shock protein binding
PTUN_RS20605	COG1918	ferrous iron import across plasma membrane
PTUN_RS20610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PTUN_RS20615	COG1285	pathogenesis
PTUN_RS20625	COG2193	ferroxidase activity
PTUN_RS20635	COG1960	acyl-CoA dehydrogenase activity
PTUN_RS20645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PTUN_RS20665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PTUN_RS20670	COG0513	Belongs to the DEAD box helicase family
PTUN_RS20680	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PTUN_RS20690	COG0019	diaminopimelate decarboxylase activity
PTUN_RS20770	COG3501	Rhs element vgr protein
PTUN_RS20830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PTUN_RS20835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PTUN_RS20840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PTUN_RS20870	COG1012	belongs to the aldehyde dehydrogenase family
PTUN_RS20880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PTUN_RS20895	COG1640	4-alpha-glucanotransferase
PTUN_RS20900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PTUN_RS20910	COG0058	SHG alpha-glucan phosphorylase activity
PTUN_RS20915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PTUN_RS20925	COG1741	Belongs to the pirin family
PTUN_RS20930	COG0435	Glutathione S-transferase
PTUN_RS20950	COG1902	pentaerythritol trinitrate reductase activity
PTUN_RS20960	COG1187	pseudouridine synthase activity
PTUN_RS20990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PTUN_RS21005	COG4221	oxidoreductase activity
PTUN_RS21015	COG0415	Belongs to the DNA photolyase family
PTUN_RS21030	COG1595	DNA-templated transcription, initiation
PTUN_RS21040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PTUN_RS21055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PTUN_RS21060	COG0583	DNA-binding transcription factor activity
PTUN_RS21075	COG3206	protein involved in exopolysaccharide biosynthesis
PTUN_RS21075	COG0489	protein tyrosine kinase activity
PTUN_RS21095	COG0028	Belongs to the TPP enzyme family
PTUN_RS21100	COG0473	3-isopropylmalate dehydrogenase activity
PTUN_RS21115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PTUN_RS21120	COG1611	Belongs to the LOG family
PTUN_RS21150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PTUN_RS21150	COG0140	phosphoribosyl-ATP diphosphatase activity
PTUN_RS21155	COG0107	imidazoleglycerol-phosphate synthase activity
PTUN_RS21160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PTUN_RS21165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PTUN_RS21170	COG0131	Imidazoleglycerol-phosphate dehydratase
PTUN_RS21170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PTUN_RS21175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PTUN_RS21180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PTUN_RS21185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PTUN_RS21195	COG1199	ATP-dependent helicase activity
PTUN_RS21210	COG1785	Belongs to the alkaline phosphatase family
PTUN_RS21220	COG0318	PFAM AMP-dependent synthetase and ligase
PTUN_RS21225	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PTUN_RS21230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PTUN_RS21235	COG2894	cell division
PTUN_RS21240	COG0850	regulation of cytokinetic process
PTUN_RS21245	COG3100	YcgL domain-containing protein
PTUN_RS21250	COG2951	lytic endotransglycosylase activity
PTUN_RS21255	COG2983	Belongs to the UPF0260 family
PTUN_RS21280	COG3537	Alpha-1,2-mannosidase
PTUN_RS21300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PTUN_RS21305	COG1741	Belongs to the pirin family
PTUN_RS21310	COG1115	amino acid carrier protein
PTUN_RS21340	COG1136	(ABC) transporter
PTUN_RS21345	COG1136	(ABC) transporter
PTUN_RS21345	COG0577	efflux transmembrane transporter activity
PTUN_RS21350	COG0577	efflux transmembrane transporter activity
PTUN_RS21350	COG1136	(ABC) transporter
PTUN_RS21355	COG2204	response regulator
PTUN_RS21360	COG3852	Histidine kinase
PTUN_RS21390	COG1247	-acetyltransferase
PTUN_RS21405	COG1335	isochorismatase
PTUN_RS21485	COG2161	toxin-antitoxin pair type II binding
PTUN_RS21490	COG4115	mRNA cleavage
PTUN_RS21505	COG0010	Belongs to the arginase family
PTUN_RS21510	COG1166	arginine decarboxylase activity
PTUN_RS21535	COG0811	peptide transport
PTUN_RS21540	COG0811	peptide transport
PTUN_RS21545	COG0848	biopolymer transport protein
PTUN_RS21570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PTUN_RS21620	COG4807	Protein conserved in bacteria
PTUN_RS21625	COG0513	Belongs to the DEAD box helicase family
PTUN_RS21635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PTUN_RS21635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PTUN_RS21650	COG0277	FAD linked oxidase domain protein
PTUN_RS21650	COG0247	lactate metabolic process
PTUN_RS21660	COG0574	Belongs to the PEP-utilizing enzyme family
PTUN_RS21660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PTUN_RS21665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PTUN_RS21670	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PTUN_RS21675	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
PTUN_RS21680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily