locus-tag	class	description
AM474_RS00055	COG1960	acyl-CoA dehydrogenase activity
AM474_RS00060	COG0183	Belongs to the thiolase family
AM474_RS00070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM474_RS00080	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS00115	COG0659	secondary active sulfate transmembrane transporter activity
AM474_RS00140	COG3706	GGDEF domain
AM474_RS00140	COG2203	Gaf domain
AM474_RS00140	COG5001	Diguanylate cyclase
AM474_RS00140	COG4251	negative regulation of phosphorylation
AM474_RS00165	COG4191	Histidine kinase
AM474_RS00195	COG1522	sequence-specific DNA binding
AM474_RS00210	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM474_RS00230	COG2205	protein histidine kinase activity
AM474_RS00230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM474_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00270	COG1960	acyl-CoA dehydrogenase activity
AM474_RS00275	COG1024	Enoyl-CoA hydratase
AM474_RS00285	COG1960	acyl-CoA dehydrogenase activity
AM474_RS00295	COG2124	cytochrome p450
AM474_RS00305	COG0183	Belongs to the thiolase family
AM474_RS00310	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM474_RS00315	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM474_RS00335	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00345	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM474_RS00355	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM474_RS00360	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00380	COG2814	Major facilitator Superfamily
AM474_RS00435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM474_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00480	COG2124	cytochrome p450
AM474_RS00485	COG1309	transcriptional regulator
AM474_RS00490	COG0445	tRNA wobble uridine modification
AM474_RS00495	COG2814	Major facilitator Superfamily
AM474_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00505	COG1024	Enoyl-CoA hydratase
AM474_RS00520	COG4447	cellulose binding
AM474_RS00535	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00540	COG0386	Belongs to the glutathione peroxidase family
AM474_RS00545	COG0583	DNA-binding transcription factor activity
AM474_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS00585	COG2124	cytochrome p450
AM474_RS00595	COG1063	alcohol dehydrogenase
AM474_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS00640	COG0789	Transcriptional regulator
AM474_RS00645	COG1960	acyl-CoA dehydrogenase activity
AM474_RS00650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM474_RS00655	COG1024	Enoyl-CoA hydratase
AM474_RS00695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM474_RS00730	COG4115	mRNA cleavage
AM474_RS00735	COG2161	toxin-antitoxin pair type II binding
AM474_RS00740	COG0582	viral genome integration into host DNA
AM474_RS00785	COG4771	TonB-dependent receptor
AM474_RS00790	COG2197	response regulator
AM474_RS00805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS00815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS00820	COG1960	acyl-CoA dehydrogenase activity
AM474_RS00830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS00835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM474_RS00840	COG0583	DNA-binding transcription factor activity
AM474_RS00880	COG2920	part of a sulfur-relay system
AM474_RS00885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM474_RS00890	COG0435	Glutathione S-transferase
AM474_RS00905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM474_RS00920	COG0492	ferredoxin-NADP+ reductase activity
AM474_RS00935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM474_RS00940	COG0542	response to heat
AM474_RS00950	COG1278	Cold shock
AM474_RS00990	COG2850	peptidyl-arginine hydroxylation
AM474_RS00995	COG2153	protein acetylation
AM474_RS01095	COG2226	methyltransferase
AM474_RS01110	COG2056	Na+-H+ antiporter family
AM474_RS01115	COG0840	transmembrane signaling receptor activity
AM474_RS01175	COG3604	Transcriptional regulator
AM474_RS01180	COG0720	synthase
AM474_RS01230	COG1459	type II secretion system
AM474_RS01235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM474_RS01245	COG4106	trans-aconitate 2-methyltransferase activity
AM474_RS01255	COG0583	DNA-binding transcription factor activity
AM474_RS01300	COG2819	hydrolase of the alpha beta superfamily
AM474_RS01310	COG1959	2 iron, 2 sulfur cluster binding
AM474_RS01315	COG1607	acyl-coa hydrolase
AM474_RS01390	COG0542	response to heat
AM474_RS01405	COG1280	lysine exporter protein (LysE YggA)
AM474_RS01430	COG0243	molybdopterin cofactor binding
AM474_RS01435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM474_RS01440	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM474_RS01440	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS01450	COG0789	Transcriptional regulator
AM474_RS01495	COG0542	response to heat
AM474_RS01505	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM474_RS01505	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AM474_RS01515	COG3328	transposase activity
AM474_RS01560	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AM474_RS01570	COG0210	DNA helicase
AM474_RS01585	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM474_RS01595	COG0514	ATP-dependent DNA helicase (RecQ)
AM474_RS01675	COG0024	Methionine aminopeptidase
AM474_RS01705	COG1061	Type III restriction enzyme res subunit
AM474_RS01715	COG3328	transposase activity
AM474_RS01740	COG1929	Belongs to the glycerate kinase type-1 family
AM474_RS01745	COG3835	regulator
AM474_RS01750	COG4644	lycopene metabolic process
AM474_RS01785	COG0789	Transcriptional regulator
AM474_RS01795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM474_RS01820	COG0659	secondary active sulfate transmembrane transporter activity
AM474_RS01825	COG0589	response to stress
AM474_RS01890	COG1358	cellular component organization or biogenesis
AM474_RS01905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM474_RS01915	COG1555	photosystem II stabilization
AM474_RS01915	COG3568	Endonuclease Exonuclease Phosphatase
AM474_RS01935	COG4974	Belongs to the 'phage' integrase family
AM474_RS01960	COG1295	ribonuclease BN
AM474_RS01970	COG1238	metal cluster binding
AM474_RS02055	COG2837	iron assimilation
AM474_RS02065	COG1024	Enoyl-CoA hydratase
AM474_RS02065	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM474_RS02075	COG1051	belongs to the nudix hydrolase family
AM474_RS02090	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AM474_RS02130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS02135	COG2116	formate transmembrane transporter activity
AM474_RS02185	COG3655	Transcriptional regulator
AM474_RS02200	COG0840	transmembrane signaling receptor activity
AM474_RS02265	COG3179	chitinase
AM474_RS02410	COG5484	DNA packaging
AM474_RS02410	COG3728	DNA packaging
AM474_RS02450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM474_RS02475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM474_RS02490	COG0454	-acetyltransferase
AM474_RS02605	COG0745	RESPONSE REGULATOR receiver
AM474_RS02615	COG2853	Lipoprotein
AM474_RS02625	COG2188	Transcriptional regulator
AM474_RS02670	COG0842	Transport permease protein
AM474_RS02675	COG1131	(ABC) transporter
AM474_RS02680	COG0625	glutathione transferase activity
AM474_RS02810	COG0629	single-stranded DNA binding
AM474_RS02815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM474_RS02830	COG0789	Transcriptional regulator
AM474_RS02840	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM474_RS02885	COG0789	Transcriptional regulator
AM474_RS03095	COG2003	Belongs to the UPF0758 family
AM474_RS03150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM474_RS03150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM474_RS03155	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM474_RS03160	COG1252	NADH dehydrogenase
AM474_RS03165	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM474_RS03230	COG0583	DNA-binding transcription factor activity
AM474_RS03245	COG0583	DNA-binding transcription factor activity
AM474_RS03260	COG2837	iron assimilation
AM474_RS03265	COG0582	viral genome integration into host DNA
AM474_RS03285	COG0625	glutathione transferase activity
AM474_RS03290	COG1956	GAF domain-containing protein
AM474_RS03295	COG2255	four-way junction helicase activity
AM474_RS03300	COG5002	protein histidine kinase activity
AM474_RS03300	COG0784	Response regulator, receiver
AM474_RS03300	COG2205	protein histidine kinase activity
AM474_RS03305	COG1846	Transcriptional regulator
AM474_RS03310	COG0386	Belongs to the glutathione peroxidase family
AM474_RS03320	COG0436	Aminotransferase
AM474_RS03335	COG2866	Carboxypeptidase
AM474_RS03375	COG3384	dioxygenase
AM474_RS03385	COG1024	Enoyl-CoA hydratase
AM474_RS03395	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AM474_RS03400	COG3214	Protein conserved in bacteria
AM474_RS03410	COG0583	DNA-binding transcription factor activity
AM474_RS03420	COG0583	DNA-binding transcription factor activity
AM474_RS03425	COG1846	Transcriptional regulator
AM474_RS03430	COG1764	response to oxidative stress
AM474_RS03470	COG4181	ATPase activity
AM474_RS03475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM474_RS03490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM474_RS03505	COG2259	Doxx family
AM474_RS03510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AM474_RS03515	COG0084	hydrolase, TatD family'
AM474_RS03560	COG0714	Associated with various cellular activities
AM474_RS03570	COG0583	DNA-binding transcription factor activity
AM474_RS03580	COG0583	DNA-binding transcription factor activity
AM474_RS03610	COG1309	transcriptional regulator
AM474_RS03625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM474_RS03630	COG1960	acyl-CoA dehydrogenase activity
AM474_RS03635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AM474_RS03650	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS03665	COG1595	DNA-templated transcription, initiation
AM474_RS03670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM474_RS03680	COG2197	response regulator
AM474_RS03685	COG2885	chlorophyll binding
AM474_RS03685	COG3047	cAMP biosynthetic process
AM474_RS03715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM474_RS03745	COG1120	ATPase activity
AM474_RS03755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM474_RS03785	COG0840	transmembrane signaling receptor activity
AM474_RS03790	COG0583	DNA-binding transcription factor activity
AM474_RS03795	COG1473	amidohydrolase
AM474_RS03800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM474_RS03805	COG4215	(ABC) transporter
AM474_RS03810	COG4160	amino acid transport
AM474_RS03845	COG1309	transcriptional regulator
AM474_RS03850	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS03855	COG2814	Major facilitator Superfamily
AM474_RS03880	COG2233	PERMEase
AM474_RS03895	COG0183	Belongs to the thiolase family
AM474_RS03910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM474_RS03995	COG0084	hydrolase, TatD family'
AM474_RS04015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM474_RS04025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM474_RS04055	COG1399	metal-binding, possibly nucleic acid-binding protein
AM474_RS04065	COG0616	signal peptide processing
AM474_RS04065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM474_RS04070	COG0546	phosphoglycolate phosphatase activity
AM474_RS04085	COG1530	ribonuclease E activity
AM474_RS04095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM474_RS04115	COG0848	biopolymer transport protein
AM474_RS04120	COG0811	peptide transport
AM474_RS04125	COG0658	competence protein
AM474_RS04125	COG2333	competence protein COMEC
AM474_RS04145	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM474_RS04160	COG0584	glycerophosphoryl diester phosphodiesterase
AM474_RS04175	COG1477	protein flavinylation
AM474_RS04210	COG1113	amino acid transport
AM474_RS04220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM474_RS04300	COG0589	response to stress
AM474_RS04310	COG0488	(ABC) transporter
AM474_RS04315	COG0741	lytic transglycosylase activity
AM474_RS04335	COG1070	Carbohydrate kinase
AM474_RS04340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM474_RS04360	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM474_RS04390	COG1309	transcriptional regulator
AM474_RS04395	COG0625	glutathione transferase activity
AM474_RS04405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM474_RS04415	COG0004	ammonium transporteR
AM474_RS04445	COG2197	response regulator
AM474_RS04450	COG3171	Protein conserved in bacteria
AM474_RS04455	COG2027	D-alanyl-D-alanine carboxypeptidase
AM474_RS04470	COG3130	regulation of translation
AM474_RS04520	COG0297	glycogen (starch) synthase activity
AM474_RS04545	COG2342	PFAM TM1410 hypothetical-related protein
AM474_RS04560	COG0714	Associated with various cellular activities
AM474_RS04600	COG0745	RESPONSE REGULATOR receiver
AM474_RS04635	COG0308	aminopeptidase N
AM474_RS04645	COG3139	Protein of unknown function (DUF1315)
AM474_RS04655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM474_RS04680	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS04680	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM474_RS04780	COG1286	toxin biosynthetic process
AM474_RS04785	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM474_RS04790	COG0285	dihydrofolate synthase activity
AM474_RS04830	COG2226	methyltransferase
AM474_RS04850	COG0251	oxidation-reduction process
AM474_RS04855	COG0583	DNA-binding transcription factor activity
AM474_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS04890	COG0800	Aldolase
AM474_RS04895	COG0596	Alpha beta hydrolase
AM474_RS04930	COG0583	DNA-binding transcription factor activity
AM474_RS04970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM474_RS04995	COG1086	Polysaccharide biosynthesis protein
AM474_RS05050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM474_RS05080	COG0402	S-adenosylhomocysteine deaminase activity
AM474_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS05110	COG0786	glutamate:sodium symporter activity
AM474_RS05160	COG0676	glucose-6-phosphate 1-epimerase activity
AM474_RS05175	COG3842	ATPase activity
AM474_RS05180	COG0395	ABC-type sugar transport system, permease component
AM474_RS05185	COG1175	transmembrane transport
AM474_RS05235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM474_RS05240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AM474_RS05245	COG0009	L-threonylcarbamoyladenylate synthase
AM474_RS05250	COG0613	PHP domain protein
AM474_RS05260	COG2350	Protein conserved in bacteria
AM474_RS05270	COG0745	RESPONSE REGULATOR receiver
AM474_RS05290	COG0778	Nitroreductase
AM474_RS05295	COG0727	PFAM Uncharacterised protein family (UPF0153)
AM474_RS05300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM474_RS05305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM474_RS05310	COG1127	ABC transporter
AM474_RS05340	COG0438	transferase activity, transferring glycosyl groups
AM474_RS05340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM474_RS05355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM474_RS05380	COG0702	epimerase
AM474_RS05385	COG0509	glycine decarboxylation via glycine cleavage system
AM474_RS05410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM474_RS05420	COG1132	(ABC) transporter
AM474_RS05450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM474_RS05455	COG3162	membrane
AM474_RS05475	COG2853	Lipoprotein
AM474_RS05490	COG1560	Kdo2-lipid A biosynthetic process
AM474_RS05500	COG2894	cell division
AM474_RS05510	COG0564	pseudouridine synthase activity
AM474_RS05540	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM474_RS05555	COG0560	Phosphoserine phosphatase
AM474_RS05560	COG0604	alcohol dehydrogenase
AM474_RS05560	COG3321	synthase
AM474_RS05570	COG2200	EAL domain
AM474_RS05620	COG0385	Bile acid
AM474_RS05625	COG2076	Multidrug Resistance protein
AM474_RS05640	COG4772	TonB-dependent receptor
AM474_RS05655	COG2205	protein histidine kinase activity
AM474_RS05660	COG1201	RNA secondary structure unwinding
AM474_RS05735	COG1595	DNA-templated transcription, initiation
AM474_RS05790	COG0537	adenosine 5'-monophosphoramidase activity
AM474_RS05800	COG1643	Atp-dependent helicase
AM474_RS05815	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS05820	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS05825	COG2267	carboxylic ester hydrolase activity
AM474_RS05830	COG2030	dehydratase
AM474_RS05835	COG2814	Major facilitator Superfamily
AM474_RS05875	COG0589	response to stress
AM474_RS05890	COG2084	Dehydrogenase
AM474_RS05895	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM474_RS05905	COG3639	organic phosphonate transmembrane transporter activity
AM474_RS05940	COG0583	DNA-binding transcription factor activity
AM474_RS05985	COG4221	oxidoreductase activity
AM474_RS05990	COG2124	cytochrome p450
AM474_RS06030	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM474_RS06055	COG5001	Diguanylate cyclase
AM474_RS06055	COG3706	GGDEF domain
AM474_RS06055	COG2203	Gaf domain
AM474_RS06055	COG4251	negative regulation of phosphorylation
AM474_RS06060	COG0514	ATP-dependent DNA helicase (RecQ)
AM474_RS06070	COG0745	RESPONSE REGULATOR receiver
AM474_RS06085	COG0835	chemotaxis
AM474_RS06085	COG0784	Response regulator, receiver
AM474_RS06105	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AM474_RS06130	COG0697	spore germination
AM474_RS06140	COG1566	PFAM secretion protein HlyD family protein
AM474_RS06235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM474_RS06245	COG3454	Phosphonate metabolism
AM474_RS06250	COG4778	phosphonate C-P lyase system protein PhnL
AM474_RS06255	COG4107	phosphonate C-P lyase system protein PhnK
AM474_RS06260	COG3627	carbon phosphorus lyase activity
AM474_RS06265	COG3626	phosphonate metabolism
AM474_RS06275	COG3624	Phosphonate C-P lyase system protein PhnG
AM474_RS06280	COG2188	Transcriptional regulator
AM474_RS06285	COG3639	organic phosphonate transmembrane transporter activity
AM474_RS06290	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM474_RS06365	COG0583	DNA-binding transcription factor activity
AM474_RS06435	COG1629	transport
AM474_RS06475	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM474_RS06520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AM474_RS06530	COG1024	Enoyl-CoA hydratase
AM474_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS06555	COG1346	cytolysis
AM474_RS06560	COG1380	Effector of murein hydrolase LrgA
AM474_RS06565	COG0583	DNA-binding transcription factor activity
AM474_RS06590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM474_RS06615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM474_RS06625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS06630	COG0431	NADPH-dependent FMN reductase
AM474_RS06640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM474_RS06645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS06650	COG0450	alkyl hydroperoxide reductase
AM474_RS06670	COG0183	Belongs to the thiolase family
AM474_RS06700	COG0367	asparagine synthase
AM474_RS06705	COG0189	ligase activity
AM474_RS06705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM474_RS06710	COG1363	Peptidase, m42
AM474_RS06715	COG2205	protein histidine kinase activity
AM474_RS06715	COG0784	Response regulator, receiver
AM474_RS06715	COG5002	protein histidine kinase activity
AM474_RS06735	COG0513	Belongs to the DEAD box helicase family
AM474_RS06740	COG0477	Major facilitator Superfamily
AM474_RS06745	COG0668	transmembrane transport
AM474_RS06750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM474_RS06770	COG0791	NLP P60 protein
AM474_RS06820	COG0489	protein tyrosine kinase activity
AM474_RS06890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM474_RS06900	COG2264	protein methyltransferase activity
AM474_RS06905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM474_RS06940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS06970	COG0450	alkyl hydroperoxide reductase
AM474_RS06985	COG2223	nitrite transmembrane transporter activity
AM474_RS06990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM474_RS06995	COG0243	molybdopterin cofactor binding
AM474_RS07015	COG3842	ATPase activity
AM474_RS07130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM474_RS07130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM474_RS07130	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM474_RS07135	COG1105	Belongs to the carbohydrate kinase PfkB family
AM474_RS07145	COG1609	Transcriptional regulator
AM474_RS07150	COG0084	hydrolase, TatD family'
AM474_RS07160	COG0583	DNA-binding transcription factor activity
AM474_RS07200	COG2814	Major facilitator Superfamily
AM474_RS07245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM474_RS07285	COG0583	DNA-binding transcription factor activity
AM474_RS07295	COG0183	Belongs to the thiolase family
AM474_RS07300	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM474_RS07305	COG1024	Enoyl-CoA hydratase
AM474_RS07310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM474_RS07315	COG1960	acyl-CoA dehydrogenase activity
AM474_RS07320	COG0583	DNA-binding transcription factor activity
AM474_RS07330	COG0477	Major facilitator Superfamily
AM474_RS07335	COG2169	Transcriptional regulator
AM474_RS07335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM474_RS07340	COG0531	amino acid
AM474_RS07365	COG0069	glutamate synthase activity
AM474_RS07385	COG3148	PFAM DTW domain containing protein
AM474_RS07395	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM474_RS07400	COG1177	transmembrane transport
AM474_RS07415	COG3530	Putative quorum-sensing-regulated virulence factor
AM474_RS07420	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AM474_RS07425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM474_RS07445	COG1546	Belongs to the CinA family
AM474_RS07500	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM474_RS07505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM474_RS07510	COG0583	DNA-binding transcription factor activity
AM474_RS07515	COG2391	methyltransferase activity
AM474_RS07565	COG1115	amino acid carrier protein
AM474_RS07645	COG0024	Methionine aminopeptidase
AM474_RS07655	COG0436	Aminotransferase
AM474_RS07660	COG0025	NhaP-type Na H and K H
AM474_RS07680	COG1393	Belongs to the ArsC family
AM474_RS07685	COG1280	lysine exporter protein (LysE YggA)
AM474_RS07700	COG2166	iron-sulfur cluster assembly
AM474_RS07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS07770	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AM474_RS07775	COG1801	Protein of unknown function DUF72
AM474_RS07785	COG1214	PFAM Peptidase M22, glycoprotease
AM474_RS07805	COG0789	Transcriptional regulator
AM474_RS07820	COG2885	chlorophyll binding
AM474_RS07835	COG3064	Membrane
AM474_RS07835	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM474_RS07835	COG1073	alpha beta
AM474_RS07870	COG5001	Diguanylate cyclase
AM474_RS07870	COG3706	GGDEF domain
AM474_RS07870	COG2203	Gaf domain
AM474_RS07870	COG4251	negative regulation of phosphorylation
AM474_RS07905	COG0477	Major facilitator Superfamily
AM474_RS07925	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AM474_RS07930	COG2197	response regulator
AM474_RS07975	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS07985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM474_RS08025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM474_RS08050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM474_RS08070	COG1607	acyl-coa hydrolase
AM474_RS08095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM474_RS08105	COG4536	flavin adenine dinucleotide binding
AM474_RS08115	COG0477	Major facilitator Superfamily
AM474_RS08155	COG2188	Transcriptional regulator
AM474_RS08160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM474_RS08165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM474_RS08170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM474_RS08170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM474_RS08215	COG0590	tRNA wobble adenosine to inosine editing
AM474_RS08220	COG2132	Multicopper oxidase
AM474_RS08245	COG3846	protein secretion by the type IV secretion system
AM474_RS08260	COG3451	type IV secretory pathway VirB4
AM474_RS08270	COG3838	Conjugal transfer protein Trbc
AM474_RS08275	COG4962	Type ii secretion system protein e
AM474_RS08295	COG0583	DNA-binding transcription factor activity
AM474_RS08320	COG0633	Ferredoxin
AM474_RS08325	COG0789	Transcriptional regulator
AM474_RS08335	COG0640	Transcriptional regulator
AM474_RS08340	COG2814	Major facilitator Superfamily
AM474_RS08345	COG1937	Protein conserved in bacteria
AM474_RS08350	COG1230	cation diffusion facilitator family transporter
AM474_RS08355	COG0640	Transcriptional regulator
AM474_RS08380	COG2814	Major facilitator Superfamily
AM474_RS08390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM474_RS08405	COG4959	Type IV secretory pathway protease TraF
AM474_RS08465	COG5489	Protein of unknown function (DUF736)
AM474_RS08490	COG2003	Belongs to the UPF0758 family
AM474_RS08535	COG0582	viral genome integration into host DNA
AM474_RS08585	COG0583	DNA-binding transcription factor activity
AM474_RS08590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM474_RS08600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM474_RS08615	COG1335	isochorismatase
AM474_RS08625	COG2847	Copper chaperone PCu(A)C
AM474_RS08635	COG0739	heme binding
AM474_RS08675	COG0667	Aldo Keto reductase
AM474_RS08685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM474_RS08690	COG0436	Aminotransferase
AM474_RS08780	COG1045	serine acetyltransferase
AM474_RS08795	COG3134	Outer membrane lipoprotein
AM474_RS08810	COG1862	Preprotein translocase
AM474_RS08830	COG2200	EAL domain
AM474_RS08840	COG0795	lipopolysaccharide-transporting ATPase activity
AM474_RS08845	COG0795	lipopolysaccharide-transporting ATPase activity
AM474_RS08890	COG4120	Belongs to the binding-protein-dependent transport system permease family
AM474_RS08895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AM474_RS08900	COG0471	metal ion transport
AM474_RS08900	COG0490	domain, Protein
AM474_RS08930	COG0640	Transcriptional regulator
AM474_RS08945	COG0583	DNA-binding transcription factor activity
AM474_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM474_RS09020	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS09050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM474_RS09055	COG4771	TonB-dependent receptor
AM474_RS09070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM474_RS09075	COG2181	nitrate reductase activity
AM474_RS09080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AM474_RS09085	COG1140	nitrate reductase beta subunit
AM474_RS09090	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AM474_RS09095	COG2223	nitrite transmembrane transporter activity
AM474_RS09105	COG3850	Histidine kinase
AM474_RS09110	COG2197	response regulator
AM474_RS09125	COG2226	methyltransferase
AM474_RS09130	COG0300	oxidoreductase activity
AM474_RS09185	COG1566	PFAM secretion protein HlyD family protein
AM474_RS09205	COG0583	DNA-binding transcription factor activity
AM474_RS09215	COG0697	spore germination
AM474_RS09225	COG1595	DNA-templated transcription, initiation
AM474_RS09230	COG3712	iron ion homeostasis
AM474_RS09235	COG4772	TonB-dependent receptor
AM474_RS09285	COG3154	lipid carrier protein
AM474_RS09290	COG0826	peptidase U32
AM474_RS09295	COG0826	peptidase U32
AM474_RS09300	COG0303	'Molybdopterin
AM474_RS09305	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM474_RS09315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM474_RS09340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AM474_RS09375	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS09380	COG0183	Belongs to the thiolase family
AM474_RS09390	COG2207	Transcriptional regulator
AM474_RS09400	COG1294	oxidase, subunit
AM474_RS09405	COG1271	oxidase subunit
AM474_RS09420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM474_RS09425	COG1297	OPT oligopeptide transporter protein
AM474_RS09430	COG2175	clavaminate synthase activity
AM474_RS09435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM474_RS09445	COG4521	taurine ABC transporter
AM474_RS09465	COG1946	Acyl-CoA thioesterase
AM474_RS09485	COG2205	protein histidine kinase activity
AM474_RS09485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM474_RS09490	COG2202	Pas domain
AM474_RS09490	COG2199	diguanylate cyclase activity
AM474_RS09490	COG2200	EAL domain
AM474_RS09495	COG2197	response regulator
AM474_RS09510	COG0513	Belongs to the DEAD box helicase family
AM474_RS09520	COG3416	Protein conserved in bacteria
AM474_RS09640	COG1061	Type III restriction enzyme res subunit
AM474_RS09675	COG1643	Atp-dependent helicase
AM474_RS09685	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM474_RS09725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM474_RS09735	COG1960	acyl-CoA dehydrogenase activity
AM474_RS09745	COG0784	Response regulator, receiver
AM474_RS09745	COG2198	Histidine kinase
AM474_RS09745	COG2205	protein histidine kinase activity
AM474_RS09750	COG0351	phosphomethylpyrimidine kinase
AM474_RS09780	COG1702	phosphate starvation-inducible protein PhoH
AM474_RS09790	COG4535	Mg2 and Co2 transporter CorC
AM474_RS09800	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM474_RS09835	COG2951	lytic endotransglycosylase activity
AM474_RS09865	COG1686	Belongs to the peptidase S11 family
AM474_RS09875	COG2951	lytic endotransglycosylase activity
AM474_RS09880	COG0772	Belongs to the SEDS family
AM474_RS09885	COG0768	penicillin binding
AM474_RS09925	COG0586	Pfam SNARE associated Golgi protein
AM474_RS09935	COG1346	cytolysis
AM474_RS09955	COG0702	epimerase
AM474_RS09970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM474_RS09975	COG3284	Transcriptional regulator
AM474_RS09985	COG0531	amino acid
AM474_RS09990	COG4303	Ethanolamine ammonia lyase large subunit
AM474_RS10000	COG0456	acetyltransferase
AM474_RS10015	COG0586	Pfam SNARE associated Golgi protein
AM474_RS10020	COG3228	Belongs to the MtfA family
AM474_RS10030	COG0745	RESPONSE REGULATOR receiver
AM474_RS10050	COG5002	protein histidine kinase activity
AM474_RS10055	COG1131	(ABC) transporter
AM474_RS10075	COG4948	Mandelate Racemase Muconate Lactonizing
AM474_RS10085	COG0142	geranyltranstransferase activity
AM474_RS10095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM474_RS10110	COG3577	Aspartyl protease
AM474_RS10120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM474_RS10125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM474_RS10150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM474_RS10150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM474_RS10170	COG2264	protein methyltransferase activity
AM474_RS10175	COG3118	belongs to the thioredoxin family
AM474_RS10205	COG3047	cAMP biosynthetic process
AM474_RS10215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM474_RS10235	COG0531	amino acid
AM474_RS10275	COG2197	response regulator
AM474_RS10295	COG3188	usher protein
AM474_RS10300	COG3121	Chaperone
AM474_RS10315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM474_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS10370	COG2271	Major facilitator Superfamily
AM474_RS10375	COG1063	alcohol dehydrogenase
AM474_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS10400	COG0583	DNA-binding transcription factor activity
AM474_RS10445	COG1611	Belongs to the LOG family
AM474_RS10485	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS10490	COG3384	dioxygenase
AM474_RS10500	COG2271	Major facilitator Superfamily
AM474_RS10505	COG3971	2-oxopent-4-enoate hydratase activity
AM474_RS10520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM474_RS10530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM474_RS10535	COG3278	Belongs to the heme-copper respiratory oxidase family
AM474_RS10545	COG1846	Transcriptional regulator
AM474_RS10550	COG2814	Major facilitator Superfamily
AM474_RS10585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS10610	COG3284	Transcriptional regulator
AM474_RS10620	COG3199	ATP-NAD kinase
AM474_RS10625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM474_RS10630	COG0022	dehydrogenase e1 component
AM474_RS10640	COG1063	alcohol dehydrogenase
AM474_RS10645	COG4991	sh3 domain protein
AM474_RS10650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM474_RS10655	COG1629	transport
AM474_RS10655	COG4774	siderophore transport
AM474_RS10665	COG1120	ATPase activity
AM474_RS10670	COG4592	Periplasmic binding protein
AM474_RS10675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM474_RS10680	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM474_RS10685	COG0154	amidase activity
AM474_RS10715	COG1959	2 iron, 2 sulfur cluster binding
AM474_RS10720	COG0492	ferredoxin-NADP+ reductase activity
AM474_RS10725	COG0693	protein deglycase activity
AM474_RS10735	COG0251	oxidation-reduction process
AM474_RS10750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM474_RS10760	COG2226	methyltransferase
AM474_RS10810	COG2271	Major facilitator Superfamily
AM474_RS10815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM474_RS10820	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS10830	COG4566	intracellular signal transduction
AM474_RS10835	COG4191	Histidine kinase
AM474_RS10845	COG1960	acyl-CoA dehydrogenase activity
AM474_RS10850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM474_RS10870	COG2706	6-phosphogluconolactonase activity
AM474_RS10880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS10885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS10980	COG2226	methyltransferase
AM474_RS10980	COG3433	isochorismatase activity
AM474_RS10980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM474_RS10985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM474_RS10985	COG2226	methyltransferase
AM474_RS10985	COG3433	isochorismatase activity
AM474_RS10995	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM474_RS11020	COG2814	Major facilitator Superfamily
AM474_RS11145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM474_RS11310	COG0739	heme binding
AM474_RS11340	COG1981	membrane
AM474_RS11365	COG0537	adenosine 5'-monophosphoramidase activity
AM474_RS11380	COG1765	OsmC-like protein
AM474_RS11480	COG3179	chitinase
AM474_RS11565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM474_RS11590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM474_RS11600	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM474_RS11610	COG3842	ATPase activity
AM474_RS11620	COG2197	response regulator
AM474_RS11635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AM474_RS11685	COG2766	serine protein kinase
AM474_RS11695	COG2719	SpoVR family
AM474_RS11715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM474_RS11860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM474_RS11865	COG4977	sequence-specific DNA binding
AM474_RS11865	COG1917	Cupin 2, conserved barrel domain protein
AM474_RS11870	COG3152	Membrane
AM474_RS11875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM474_RS11880	COG1451	nucleotide metabolic process
AM474_RS11885	COG2081	HI0933 family
AM474_RS11925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM474_RS11930	COG3622	Belongs to the hyi family
AM474_RS11940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM474_RS11945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM474_RS12000	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM474_RS12010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS12035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM474_RS12045	COG2258	MOSC domain
AM474_RS12050	COG0583	DNA-binding transcription factor activity
AM474_RS12055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM474_RS12140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM474_RS12140	COG1648	precorrin-2 dehydrogenase activity
AM474_RS12150	COG1960	acyl-CoA dehydrogenase activity
AM474_RS12160	COG1960	acyl-CoA dehydrogenase activity
AM474_RS12165	COG1960	acyl-CoA dehydrogenase activity
AM474_RS12185	COG1073	alpha beta
AM474_RS12185	COG2226	methyltransferase
AM474_RS12205	COG1984	allophanate hydrolase subunit 2
AM474_RS12220	COG0511	ligase activity, forming carbon-carbon bonds
AM474_RS12240	COG1040	competence protein
AM474_RS12245	COG5544	Lipoprotein
AM474_RS12250	COG3585	molybdate ion transport
AM474_RS12250	COG2005	Transcriptional regulator
AM474_RS12285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM474_RS12305	COG1953	Uracil, thiamine, allantoin
AM474_RS12310	COG1309	transcriptional regulator
AM474_RS12320	COG0625	glutathione transferase activity
AM474_RS12325	COG1595	DNA-templated transcription, initiation
AM474_RS12330	COG3712	iron ion homeostasis
AM474_RS12335	COG4774	siderophore transport
AM474_RS12365	COG4452	Inner membrane protein CreD
AM474_RS12370	COG2205	protein histidine kinase activity
AM474_RS12375	COG0745	RESPONSE REGULATOR receiver
AM474_RS12385	COG0204	Acyl-transferase
AM474_RS12395	COG0542	response to heat
AM474_RS12405	COG0477	Major facilitator Superfamily
AM474_RS12410	COG0189	ligase activity
AM474_RS12410	COG4067	protein conserved in archaea
AM474_RS12420	COG0513	Belongs to the DEAD box helicase family
AM474_RS12425	COG1289	transmembrane transporter activity
AM474_RS12435	COG0330	HflC and HflK could
AM474_RS12445	COG0306	phosphate transporter
AM474_RS12455	COG0583	DNA-binding transcription factor activity
AM474_RS12460	COG1960	acyl-CoA dehydrogenase activity
AM474_RS12475	COG1953	Uracil, thiamine, allantoin
AM474_RS12495	COG0493	'glutamate synthase
AM474_RS12510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM474_RS12515	COG0402	S-adenosylhomocysteine deaminase activity
AM474_RS12520	COG1309	transcriptional regulator
AM474_RS12545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM474_RS12550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM474_RS12560	COG0513	Belongs to the DEAD box helicase family
AM474_RS12590	COG3038	cytochrome b561
AM474_RS12610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM474_RS12640	COG0643	Histidine kinase
AM474_RS12640	COG2198	Histidine kinase
AM474_RS12640	COG0784	Response regulator, receiver
AM474_RS12705	COG0626	cystathionine gamma-synthase activity
AM474_RS12750	COG1872	DUF167
AM474_RS12755	COG1160	GTP binding
AM474_RS12765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM474_RS12765	COG2813	Specifically methylates the guanine in position
AM474_RS12780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM474_RS12815	COG2363	Small membrane protein
AM474_RS12835	COG2177	Part of the ABC transporter FtsEX involved in
AM474_RS12840	COG2884	Cell division ATP-binding protein ftsE
AM474_RS12845	COG0552	protein localization to endoplasmic reticulum
AM474_RS12850	COG0612	Peptidase, M16
AM474_RS12855	COG0612	Peptidase, M16
AM474_RS12860	COG0742	ribosomal rna small subunit methyltransferase
AM474_RS12870	COG0429	hydrolase of the alpha beta-hydrolase fold
AM474_RS12895	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM474_RS12905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM474_RS12945	COG0693	protein deglycase activity
AM474_RS12960	COG2233	PERMEase
AM474_RS12965	COG0622	Phosphoesterase
AM474_RS12985	COG0584	glycerophosphoryl diester phosphodiesterase
AM474_RS13020	COG0730	response to heat
AM474_RS13060	COG0702	epimerase
AM474_RS13070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM474_RS13090	COG2234	aminopeptidase activity
AM474_RS13095	COG3204	pilus organization
AM474_RS13105	COG3842	ATPase activity
AM474_RS13115	COG1177	transmembrane transport
AM474_RS13120	COG2182	Extracellular solute-binding protein
AM474_RS13125	COG0531	amino acid
AM474_RS13135	COG3111	PFAM Bacterial OB fold (BOF) protein
AM474_RS13145	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM474_RS13150	COG0277	FAD linked oxidase domain protein
AM474_RS13155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM474_RS13170	COG0765	amino acid transport
AM474_RS13225	COG1177	transmembrane transport
AM474_RS13230	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM474_RS13235	COG3842	ATPase activity
AM474_RS13255	COG0174	glutamine synthetase
AM474_RS13260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM474_RS13265	COG0174	glutamine synthetase
AM474_RS13270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM474_RS13295	COG2199	diguanylate cyclase activity
AM474_RS13335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM474_RS13345	COG4208	sulfate ABC transporter
AM474_RS13365	COG0501	Belongs to the peptidase M48B family
AM474_RS13385	COG2807	transmembrane transport
AM474_RS13390	COG0583	DNA-binding transcription factor activity
AM474_RS13405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM474_RS13415	COG0745	RESPONSE REGULATOR receiver
AM474_RS13535	COG2239	Acts as a magnesium transporter
AM474_RS13555	COG0477	Major facilitator Superfamily
AM474_RS13565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM474_RS13570	COG1309	transcriptional regulator
AM474_RS13580	COG2271	Major facilitator Superfamily
AM474_RS13600	COG0673	inositol 2-dehydrogenase activity
AM474_RS13620	COG0583	DNA-binding transcription factor activity
AM474_RS13625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM474_RS13630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM474_RS13640	COG0477	Major facilitator Superfamily
AM474_RS13650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM474_RS13655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM474_RS13660	COG1396	sequence-specific DNA binding
AM474_RS13665	COG0235	Class ii aldolase
AM474_RS13670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM474_RS13685	COG1113	amino acid transport
AM474_RS13690	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS13720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM474_RS13840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS13845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM474_RS13850	COG1116	anion transmembrane transporter activity
AM474_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS13865	COG0583	DNA-binding transcription factor activity
AM474_RS13875	COG0745	RESPONSE REGULATOR receiver
AM474_RS13880	COG0643	Histidine kinase
AM474_RS13880	COG2198	Histidine kinase
AM474_RS13885	COG0835	chemotaxis
AM474_RS13900	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AM474_RS13935	COG1309	transcriptional regulator
AM474_RS13940	COG2233	PERMEase
AM474_RS13975	COG0583	DNA-binding transcription factor activity
AM474_RS13980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS13995	COG1414	Transcriptional regulator
AM474_RS14005	COG3485	protocatechuate 3,4-dioxygenase
AM474_RS14010	COG3485	protocatechuate 3,4-dioxygenase
AM474_RS14015	COG0583	DNA-binding transcription factor activity
AM474_RS14095	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM474_RS14100	COG4603	Belongs to the binding-protein-dependent transport system permease family
AM474_RS14105	COG3845	ABC transporter
AM474_RS14115	COG0402	S-adenosylhomocysteine deaminase activity
AM474_RS14145	COG2824	Alkylphosphonate utilization operon protein PhnA
AM474_RS14170	COG0583	DNA-binding transcription factor activity
AM474_RS14210	COG2153	protein acetylation
AM474_RS14250	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AM474_RS14255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM474_RS14260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM474_RS14275	COG0659	secondary active sulfate transmembrane transporter activity
AM474_RS14405	COG1360	Flagellar Motor Protein
AM474_RS14420	COG0631	protein serine/threonine phosphatase activity
AM474_RS14425	COG2815	serine threonine protein kinase
AM474_RS14425	COG0515	serine threonine protein kinase
AM474_RS14440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM474_RS14455	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM474_RS14460	COG0339	signal peptide processing
AM474_RS14465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM474_RS14500	COG1764	response to oxidative stress
AM474_RS14515	COG0583	DNA-binding transcription factor activity
AM474_RS14545	COG0367	asparagine synthase
AM474_RS14585	COG3174	membrane
AM474_RS14635	COG3210	domain, Protein
AM474_RS14650	COG3210	domain, Protein
AM474_RS14650	COG3210	domain, Protein
AM474_RS14665	COG3360	Dodecin
AM474_RS14700	COG0583	DNA-binding transcription factor activity
AM474_RS14705	COG3119	arylsulfatase activity
AM474_RS14725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM474_RS14755	COG0758	DNA mediated transformation
AM474_RS14760	COG1652	LysM domain
AM474_RS14780	COG0569	domain protein
AM474_RS14795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AM474_RS14810	COG2818	Glycosylase
AM474_RS14825	COG2010	Cytochrome c
AM474_RS14925	COG1192	Involved in chromosome partitioning
AM474_RS14930	COG1475	DNA binding
AM474_RS14990	COG1349	DNA-binding transcription factor activity
AM474_RS15010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM474_RS15015	COG2358	TRAP transporter, solute receptor (TAXI family
AM474_RS15035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM474_RS15080	COG0523	cobalamin synthesis protein
AM474_RS15090	COG0477	Major facilitator Superfamily
AM474_RS15095	COG4651	solute:proton antiporter activity
AM474_RS15095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM474_RS15130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM474_RS15135	COG0174	glutamine synthetase
AM474_RS15140	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS15150	COG1607	acyl-coa hydrolase
AM474_RS15155	COG4651	solute:proton antiporter activity
AM474_RS15155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM474_RS15185	COG4191	Histidine kinase
AM474_RS15195	COG0531	amino acid
AM474_RS15225	COG2011	ABC-type metal ion transport system permease component
AM474_RS15240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM474_RS15250	COG0735	belongs to the Fur family
AM474_RS15255	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AM474_RS15290	COG3245	cytochrome
AM474_RS15315	COG2095	MarC family integral membrane protein
AM474_RS15320	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM474_RS15325	COG5002	protein histidine kinase activity
AM474_RS15350	COG1301	dicarboxylic acid transport
AM474_RS15355	COG0700	Nucleoside recognition
AM474_RS15380	COG0612	Peptidase, M16
AM474_RS15400	COG1690	Belongs to the RtcB family
AM474_RS15405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM474_RS15410	COG0861	Integral membrane protein TerC family
AM474_RS15415	COG2851	Citrate transporter
AM474_RS15425	COG0679	Auxin Efflux Carrier
AM474_RS15465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM474_RS15465	COG2755	lipolytic protein G-D-S-L family
AM474_RS15470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM474_RS15515	COG0438	transferase activity, transferring glycosyl groups
AM474_RS15530	COG0427	acetyl-CoA hydrolase
AM474_RS15540	COG0210	DNA helicase
AM474_RS15560	COG0826	peptidase U32
AM474_RS15565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM474_RS15580	COG0583	DNA-binding transcription factor activity
AM474_RS15585	COG0439	Biotin carboxylase
AM474_RS15590	COG0511	ligase activity, forming carbon-carbon bonds
AM474_RS15590	COG5016	pyruvate
AM474_RS15615	COG2391	methyltransferase activity
AM474_RS15630	COG0583	DNA-binding transcription factor activity
AM474_RS15720	COG1017	nitric oxide dioxygenase activity
AM474_RS15720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM474_RS15760	COG3655	Transcriptional regulator
AM474_RS15775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM474_RS15780	COG2181	nitrate reductase activity
AM474_RS15780	COG0247	lactate metabolic process
AM474_RS15785	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS15785	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM474_RS15840	COG3246	L-lysine catabolic process to acetate
AM474_RS15855	COG0657	acetylesterase activity
AM474_RS15865	COG0583	DNA-binding transcription factor activity
AM474_RS15880	COG1760	l-serine dehydratase
AM474_RS15890	COG4176	ABC-type proline glycine betaine transport system permease component
AM474_RS15895	COG4175	Glycine betaine
AM474_RS15900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM474_RS15925	COG1607	acyl-coa hydrolase
AM474_RS15930	COG0477	Major facilitator Superfamily
AM474_RS15970	COG0573	inorganic phosphate transmembrane transporter activity
AM474_RS15990	COG0739	heme binding
AM474_RS15995	COG1253	flavin adenine dinucleotide binding
AM474_RS16025	COG2186	Transcriptional regulator
AM474_RS16030	COG0277	FAD linked oxidase domain protein
AM474_RS16035	COG0277	FAD linked oxidase domain protein
AM474_RS16040	COG0247	lactate metabolic process
AM474_RS16045	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AM474_RS16085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM474_RS16090	COG0583	DNA-binding transcription factor activity
AM474_RS16100	COG4753	response regulator
AM474_RS16100	COG2207	Transcriptional regulator
AM474_RS16120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM474_RS16135	COG1561	YicC-like family, N-terminal region
AM474_RS16150	COG0708	Exodeoxyribonuclease III
AM474_RS16170	COG3245	cytochrome
AM474_RS16210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM474_RS16225	COG0747	negative chemotaxis
AM474_RS16245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM474_RS16250	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS16255	COG2814	Major facilitator Superfamily
AM474_RS16260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM474_RS16265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS16295	COG0251	oxidation-reduction process
AM474_RS16305	COG1917	Cupin 2, conserved barrel domain protein
AM474_RS16305	COG1396	sequence-specific DNA binding
AM474_RS16315	COG0427	acetyl-CoA hydrolase
AM474_RS16325	COG0028	Belongs to the TPP enzyme family
AM474_RS16330	COG0210	DNA helicase
AM474_RS16345	COG0583	DNA-binding transcription factor activity
AM474_RS16355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM474_RS16360	COG0606	chelatase, subunit chli
AM474_RS16370	COG0347	Belongs to the P(II) protein family
AM474_RS16375	COG0004	ammonium transporteR
AM474_RS16380	COG0432	Pfam Uncharacterised protein family UPF0047
AM474_RS16450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM474_RS16480	COG0598	Magnesium transport protein CorA
AM474_RS16510	COG3275	phosphorelay sensor kinase activity
AM474_RS16565	COG0488	(ABC) transporter
AM474_RS16575	COG0861	Integral membrane protein TerC family
AM474_RS16580	COG1280	lysine exporter protein (LysE YggA)
AM474_RS16585	COG0672	)-iron permease
AM474_RS16595	COG2050	protein possibly involved in aromatic compounds catabolism
AM474_RS16600	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM474_RS16605	COG0586	Pfam SNARE associated Golgi protein
AM474_RS16620	COG0248	Ppx GppA phosphatase
AM474_RS16635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM474_RS16635	COG2755	lipolytic protein G-D-S-L family
AM474_RS16650	COG2271	Major facilitator Superfamily
AM474_RS16665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS16670	COG1129	ABC transporter
AM474_RS16670	COG0842	Transport permease protein
AM474_RS16675	COG0842	Transport permease protein
AM474_RS16685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM474_RS16710	COG0006	proline dipeptidase activity
AM474_RS16715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM474_RS16725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM474_RS16740	COG0583	DNA-binding transcription factor activity
AM474_RS16750	COG1178	ABC-type Fe3 transport system permease component
AM474_RS16780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM474_RS16785	COG3025	triphosphatase activity
AM474_RS16790	COG1392	Phosphate transport regulator
AM474_RS16795	COG0306	phosphate transporter
AM474_RS16825	COG2183	response to ionizing radiation
AM474_RS16850	COG4067	protein conserved in archaea
AM474_RS16850	COG0189	ligase activity
AM474_RS16855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM474_RS16885	COG0778	Nitroreductase
AM474_RS16895	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM474_RS16895	COG1024	Enoyl-CoA hydratase
AM474_RS16900	COG1960	acyl-CoA dehydrogenase activity
AM474_RS16905	COG1454	alcohol dehydrogenase
AM474_RS16910	COG0824	Thioesterase
AM474_RS16920	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AM474_RS16940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM474_RS16950	COG1652	LysM domain
AM474_RS16955	COG1011	Hydrolase
AM474_RS16960	COG0494	nUDIX hydrolase
AM474_RS16965	COG1218	3'(2'),5'-bisphosphate nucleotidase
AM474_RS17030	COG1091	dTDP-4-dehydrorhamnose reductase activity
AM474_RS17035	COG1088	dTDP-glucose 4,6-dehydratase activity
AM474_RS17045	COG2814	Major facilitator Superfamily
AM474_RS17050	COG1566	PFAM secretion protein HlyD family protein
AM474_RS17060	COG1846	Transcriptional regulator
AM474_RS17095	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS17105	COG0673	inositol 2-dehydrogenase activity
AM474_RS17115	COG1194	a g-specific adenine glycosylase
AM474_RS17125	COG0579	oxidoreductase
AM474_RS17185	COG2861	carbohydrate metabolic process
AM474_RS17190	COG0793	Belongs to the peptidase S41A family
AM474_RS17195	COG4942	peptidase
AM474_RS17225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM474_RS17245	COG3852	Histidine kinase
AM474_RS17260	COG0668	transmembrane transport
AM474_RS17285	COG1217	gtp-binding protein TYPA
AM474_RS17290	COG0789	Transcriptional regulator
AM474_RS17340	COG0402	S-adenosylhomocysteine deaminase activity
AM474_RS17375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM474_RS17395	COG4176	ABC-type proline glycine betaine transport system permease component
AM474_RS17400	COG4175	Glycine betaine
AM474_RS17405	COG2986	histidine ammonia-lyase
AM474_RS17425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM474_RS17455	COG0251	oxidation-reduction process
AM474_RS17460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM474_RS17465	COG1051	belongs to the nudix hydrolase family
AM474_RS17495	COG0765	amino acid transport
AM474_RS17500	COG1126	abc transporter atp-binding protein
AM474_RS17510	COG0840	transmembrane signaling receptor activity
AM474_RS17630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM474_RS17650	COG0281	malic enzyme
AM474_RS17795	COG2369	cell adhesion
AM474_RS17805	COG4373	Mu-like prophage FluMu protein gp28
AM474_RS17900	COG1136	(ABC) transporter
AM474_RS17900	COG0577	efflux transmembrane transporter activity
AM474_RS17975	COG0070	glutamate synthase
AM474_RS17975	COG0067	glutamate synthase
AM474_RS17975	COG0069	glutamate synthase activity
AM474_RS17980	COG0493	'glutamate synthase
AM474_RS18005	COG2814	Major facilitator Superfamily
AM474_RS18010	COG0583	DNA-binding transcription factor activity
AM474_RS18015	COG1192	Involved in chromosome partitioning
AM474_RS18030	COG2873	o-acetylhomoserine
AM474_RS18035	COG0730	response to heat
AM474_RS18045	COG1196	nuclear chromosome segregation
AM474_RS18045	COG3264	Mechanosensitive ion channel
AM474_RS18060	COG1960	acyl-CoA dehydrogenase activity
AM474_RS18065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM474_RS18110	COG0859	PFAM glycosyl transferase family 9
AM474_RS18115	COG0859	PFAM glycosyl transferase family 9
AM474_RS18120	COG0438	transferase activity, transferring glycosyl groups
AM474_RS18145	COG2192	nodulation
AM474_RS18150	COG0438	transferase activity, transferring glycosyl groups
AM474_RS18170	COG1215	transferase activity, transferring glycosyl groups
AM474_RS18195	COG1960	acyl-CoA dehydrogenase activity
AM474_RS18200	COG1960	acyl-CoA dehydrogenase activity
AM474_RS18210	COG0667	Aldo Keto reductase
AM474_RS18225	COG0583	DNA-binding transcription factor activity
AM474_RS18230	COG1519	Transferase
AM474_RS18240	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM474_RS18240	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS18270	COG0833	amino acid
AM474_RS18275	COG1024	Enoyl-CoA hydratase
AM474_RS18280	COG1960	acyl-CoA dehydrogenase activity
AM474_RS18285	COG0045	succinate-CoA ligase (ADP-forming) activity
AM474_RS18300	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM474_RS18305	COG1538	Outer membrane efflux protein
AM474_RS18320	COG0494	nUDIX hydrolase
AM474_RS18330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM474_RS18335	COG3150	esterase
AM474_RS18350	COG3577	Aspartyl protease
AM474_RS18365	COG1988	membrane-bound metal-dependent
AM474_RS18375	COG0560	Phosphoserine phosphatase
AM474_RS18375	COG3830	Belongs to the UPF0237 family
AM474_RS18380	COG5001	Diguanylate cyclase
AM474_RS18380	COG3300	MHYT domain
AM474_RS18435	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM474_RS18435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM474_RS18440	COG0802	atpase or kinase
AM474_RS18445	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM474_RS18465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM474_RS18470	COG0330	HflC and HflK could
AM474_RS18475	COG0330	HflC and HflK could
AM474_RS18505	COG0557	exoribonuclease II activity
AM474_RS18535	COG0305	Participates in initiation and elongation during chromosome replication
AM474_RS18550	COG5001	Diguanylate cyclase
AM474_RS18550	COG3300	MHYT domain
AM474_RS18575	COG0668	transmembrane transport
AM474_RS18615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM474_RS18630	COG0583	DNA-binding transcription factor activity
AM474_RS18660	COG2423	ornithine cyclodeaminase activity
AM474_RS18665	COG4221	oxidoreductase activity
AM474_RS18690	COG0583	DNA-binding transcription factor activity
AM474_RS18700	COG2814	Major facilitator Superfamily
AM474_RS18720	COG1595	DNA-templated transcription, initiation
AM474_RS18725	COG3712	iron ion homeostasis
AM474_RS18785	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AM474_RS18790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM474_RS18800	COG2193	ferroxidase activity
AM474_RS18805	COG2982	Protein involved in outer membrane biogenesis
AM474_RS18810	COG0789	Transcriptional regulator
AM474_RS18835	COG0443	Heat shock 70 kDa protein
AM474_RS18855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM474_RS18905	COG0411	ABC transporter
AM474_RS18920	COG0683	leucine binding
AM474_RS18925	COG2095	MarC family integral membrane protein
AM474_RS19015	COG0023	Translation Initiation Factor
AM474_RS19050	COG1272	protein, Hemolysin III
AM474_RS19055	COG4221	oxidoreductase activity
AM474_RS19080	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AM474_RS19105	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM474_RS19115	COG0534	Mate efflux family protein
AM474_RS19125	COG0463	Glycosyl transferase, family 2
AM474_RS19150	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS19150	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM474_RS19155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AM474_RS19160	COG3383	formate dehydrogenase (NAD+) activity
AM474_RS19160	COG0243	molybdopterin cofactor binding
AM474_RS19165	COG3383	formate dehydrogenase (NAD+) activity
AM474_RS19165	COG0243	molybdopterin cofactor binding
AM474_RS19170	COG0437	4 iron, 4 sulfur cluster binding
AM474_RS19175	COG2864	formate dehydrogenase
AM474_RS19190	COG3276	selenocysteine insertion sequence binding
AM474_RS19205	COG0531	amino acid
AM474_RS19245	COG0509	glycine decarboxylation via glycine cleavage system
AM474_RS19275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM474_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS19305	COG1522	sequence-specific DNA binding
AM474_RS19310	COG0697	spore germination
AM474_RS19330	COG0697	spore germination
AM474_RS19380	COG1620	l-lactate permease
AM474_RS19385	COG2186	Transcriptional regulator
AM474_RS19415	COG0497	DNA recombination
AM474_RS19485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM474_RS19520	COG0195	Participates in both transcription termination and antitermination
AM474_RS19620	COG3328	transposase activity
AM474_RS19630	COG4191	Histidine kinase
AM474_RS19645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM474_RS19650	COG0436	Aminotransferase
AM474_RS19665	COG2252	PERMEase
AM474_RS19675	COG2321	neutral zinc metallopeptidase
AM474_RS19685	COG0436	Aminotransferase
AM474_RS19710	COG4771	TonB-dependent receptor
AM474_RS19715	COG3720	iron ion transport
AM474_RS19720	COG4558	Periplasmic binding protein
AM474_RS19725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM474_RS19760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM474_RS19770	COG3098	single-species biofilm formation
AM474_RS19780	COG0028	Belongs to the TPP enzyme family
AM474_RS19795	COG1183	phosphatidylcholine synthase activity
AM474_RS19835	COG2995	paraquat-inducible protein a
AM474_RS19840	COG2995	paraquat-inducible protein a
AM474_RS19845	COG3008	intermembrane lipid transfer
AM474_RS19850	COG1178	ABC-type Fe3 transport system permease component
AM474_RS19855	COG1840	ABC-type Fe3 transport system, periplasmic component
AM474_RS19900	COG0456	acetyltransferase
AM474_RS19910	COG0288	reversible hydration of carbon dioxide
AM474_RS19925	COG3549	Plasmid maintenance system killer
AM474_RS19940	COG0012	GTP binding
AM474_RS19995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AM474_RS20015	COG0789	Transcriptional regulator
AM474_RS20025	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AM474_RS20030	COG1090	epimerase
AM474_RS20085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AM474_RS20145	COG1285	pathogenesis
AM474_RS20150	COG2135	peptidase activity
AM474_RS20155	COG0840	transmembrane signaling receptor activity
AM474_RS20160	COG0501	Belongs to the peptidase M48B family
AM474_RS20175	COG2119	membrane
AM474_RS20180	COG0833	amino acid
AM474_RS20190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM474_RS20230	COG2010	Cytochrome c
AM474_RS20235	COG3608	succinylglutamate desuccinylase aspartoacylase
AM474_RS20235	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM474_RS20305	COG1966	Carbon starvation protein
AM474_RS20310	COG2879	small protein
AM474_RS20315	COG0523	cobalamin synthesis protein
AM474_RS20340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS20345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS20365	COG0488	(ABC) transporter
AM474_RS20370	COG0577	efflux transmembrane transporter activity
AM474_RS20370	COG1136	(ABC) transporter
AM474_RS20375	COG0577	efflux transmembrane transporter activity
AM474_RS20375	COG1136	(ABC) transporter
AM474_RS20400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM474_RS20420	COG3541	Predicted nucleotidyltransferase
AM474_RS20425	COG1690	Belongs to the RtcB family
AM474_RS20440	COG4650	regulator
AM474_RS20465	COG1067	ATP-dependent peptidase activity
AM474_RS20485	COG0545	Peptidyl-prolyl cis-trans isomerase
AM474_RS20500	COG0142	geranyltranstransferase activity
AM474_RS20525	COG3045	CreA protein
AM474_RS20540	COG0196	riboflavin kinase activity
AM474_RS20555	COG1047	Peptidyl-prolyl cis-trans
AM474_RS20665	COG2831	hemolysin activation secretion protein
AM474_RS20670	COG3328	transposase activity
AM474_RS20675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM474_RS20680	COG1252	NADH dehydrogenase
AM474_RS20745	COG4969	Belongs to the N-Me-Phe pilin family
AM474_RS20785	COG0019	diaminopimelate decarboxylase activity
AM474_RS20795	COG2194	sulfuric ester hydrolase activity
AM474_RS20810	COG4774	siderophore transport
AM474_RS20835	COG1984	allophanate hydrolase subunit 2
AM474_RS20850	COG4608	Belongs to the ABC transporter superfamily
AM474_RS20855	COG0444	Belongs to the ABC transporter superfamily
AM474_RS20860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM474_RS20865	COG0601	transmembrane transport
AM474_RS20870	COG0747	negative chemotaxis
AM474_RS20885	COG0747	negative chemotaxis
AM474_RS20900	COG0747	negative chemotaxis
AM474_RS20905	COG0747	negative chemotaxis
AM474_RS20920	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AM474_RS20925	COG4676	Protein conserved in bacteria
AM474_RS20930	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AM474_RS20945	COG5445	Predicted secreted protein (DUF2300)
AM474_RS20950	COG4676	Protein conserved in bacteria
AM474_RS20955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM474_RS20960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM474_RS20980	COG1077	Cell shape determining protein MreB Mrl
AM474_RS20985	COG1792	Involved in formation and maintenance of cell shape
AM474_RS21000	COG1530	ribonuclease E activity
AM474_RS21010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM474_RS21015	COG0312	modulator of DNA gyrase
AM474_RS21025	COG0312	modulator of DNA gyrase
AM474_RS21080	COG1137	ATPase activity
AM474_RS21095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM474_RS21105	COG1127	ABC transporter
AM474_RS21110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM474_RS21115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM474_RS21155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM474_RS21165	COG2951	lytic endotransglycosylase activity
AM474_RS21185	COG2945	thiolester hydrolase activity
AM474_RS21195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM474_RS21210	COG1960	acyl-CoA dehydrogenase activity
AM474_RS21215	COG0667	Aldo Keto reductase
AM474_RS21230	COG0723	plastoquinol--plastocyanin reductase activity
AM474_RS21235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM474_RS21240	COG2857	Cytochrome c1
AM474_RS21245	COG0625	glutathione transferase activity
AM474_RS21250	COG2969	positive regulation of protein catabolic process
AM474_RS21255	COG2823	Periplasmic or secreted lipoprotein
AM474_RS21270	COG3107	peptidoglycan biosynthetic process
AM474_RS21310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM474_RS21325	COG0772	Belongs to the SEDS family
AM474_RS21370	COG0741	lytic transglycosylase activity
AM474_RS21370	COG1196	nuclear chromosome segregation
AM474_RS21370	COG0739	heme binding
AM474_RS21395	COG0494	nUDIX hydrolase
AM474_RS21400	COG2096	Adenosyltransferase
AM474_RS21415	COG0745	RESPONSE REGULATOR receiver
AM474_RS21425	COG0668	transmembrane transport
AM474_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS21460	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM474_RS21495	COG0745	RESPONSE REGULATOR receiver
AM474_RS21500	COG2205	protein histidine kinase activity
AM474_RS21510	COG3642	lipopolysaccharide core region biosynthetic process
AM474_RS21525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS21530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS21555	COG1704	LemA family
AM474_RS21595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM474_RS21610	COG1918	ferrous iron import across plasma membrane
AM474_RS21625	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS21630	COG2814	Major facilitator Superfamily
AM474_RS21645	COG0589	response to stress
AM474_RS21665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM474_RS21665	COG0426	domain, Protein
AM474_RS21670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM474_RS21685	COG1473	amidohydrolase
AM474_RS21695	COG0154	amidase activity
AM474_RS21710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM474_RS21725	COG0693	protein deglycase activity
AM474_RS21745	COG3706	GGDEF domain
AM474_RS21755	COG1024	Enoyl-CoA hydratase
AM474_RS21765	COG0589	response to stress
AM474_RS21795	COG0714	Associated with various cellular activities
AM474_RS21825	COG2925	Exonuclease
AM474_RS21835	COG0788	formyltetrahydrofolate deformylase activity
AM474_RS21875	COG0433	COG0433 Predicted ATPase
AM474_RS21895	COG4964	Belongs to the GSP D family
AM474_RS21955	COG0306	phosphate transporter
AM474_RS21965	COG0840	transmembrane signaling receptor activity
AM474_RS21980	COG0697	spore germination
AM474_RS21985	COG0095	Lipoate-protein ligase
AM474_RS21990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM474_RS21995	COG1074	ATP-dependent DNA helicase activity
AM474_RS22000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM474_RS22010	COG0420	3'-5' exonuclease activity
AM474_RS22150	COG2831	hemolysin activation secretion protein
AM474_RS22185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM474_RS22195	COG0583	DNA-binding transcription factor activity
AM474_RS22215	COG0154	amidase activity
AM474_RS22225	COG0463	Glycosyl transferase, family 2
AM474_RS22240	COG0583	DNA-binding transcription factor activity
AM474_RS22340	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AM474_RS22345	COG2910	NAD(P)H-binding
AM474_RS22365	COG1024	Enoyl-CoA hydratase
AM474_RS22370	COG1960	acyl-CoA dehydrogenase activity
AM474_RS22385	COG2720	vancomycin resistance protein
AM474_RS22395	COG3180	Ammonia monooxygenase
AM474_RS22475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM474_RS22540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM474_RS22550	COG4206	TonB-dependent receptor
AM474_RS22560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM474_RS22565	COG0583	DNA-binding transcription factor activity
AM474_RS22595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM474_RS22600	COG1113	amino acid transport
AM474_RS22615	COG2079	MmgE PrpD family protein
AM474_RS22630	COG0372	Belongs to the citrate synthase family
AM474_RS22640	COG1802	Transcriptional regulator
AM474_RS22650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM474_RS22675	COG0656	L-ascorbic acid biosynthetic process
AM474_RS22690	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM474_RS22705	COG0546	phosphoglycolate phosphatase activity
AM474_RS22720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM474_RS22805	COG2267	carboxylic ester hydrolase activity
AM474_RS22820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM474_RS22825	COG2885	chlorophyll binding
AM474_RS22830	COG0204	Acyl-transferase
AM474_RS22855	COG0386	Belongs to the glutathione peroxidase family
AM474_RS22860	COG1309	transcriptional regulator
AM474_RS22870	COG1307	EDD domain protein, DegV family
AM474_RS22905	COG0450	alkyl hydroperoxide reductase
AM474_RS22910	COG0492	ferredoxin-NADP+ reductase activity
AM474_RS22950	COG0271	Belongs to the BolA IbaG family
AM474_RS22970	COG5002	protein histidine kinase activity
AM474_RS22970	COG5001	Diguanylate cyclase
AM474_RS22980	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS22980	COG3321	synthase
AM474_RS22980	COG0604	alcohol dehydrogenase
AM474_RS23000	COG1113	amino acid transport
AM474_RS23060	COG0583	DNA-binding transcription factor activity
AM474_RS23065	COG0583	DNA-binding transcription factor activity
AM474_RS23070	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AM474_RS23075	COG1960	acyl-CoA dehydrogenase activity
AM474_RS23085	COG2079	MmgE PrpD family protein
AM474_RS23095	COG2301	Belongs to the HpcH HpaI aldolase family
AM474_RS23190	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AM474_RS23260	COG2239	Acts as a magnesium transporter
AM474_RS23270	COG4807	Protein conserved in bacteria
AM474_RS23290	COG3038	cytochrome b561
AM474_RS23310	COG3328	transposase activity
AM474_RS23345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM474_RS23350	COG0784	Response regulator, receiver
AM474_RS23350	COG2205	protein histidine kinase activity
AM474_RS23350	COG5002	protein histidine kinase activity
AM474_RS23380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM474_RS23385	COG3956	TIGRFAM MazG family protein
AM474_RS23395	COG3122	Protein conserved in bacteria
AM474_RS23435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM474_RS23455	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM474_RS23490	COG3118	belongs to the thioredoxin family
AM474_RS23520	COG3328	transposase activity
AM474_RS23545	COG0783	Belongs to the Dps family
AM474_RS23575	COG0824	Thioesterase
AM474_RS23605	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AM474_RS23610	COG0602	queuosine metabolic process
AM474_RS23625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM474_RS23635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM474_RS23645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM474_RS23650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM474_RS23660	COG0235	Class ii aldolase
AM474_RS23670	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS23685	COG0475	glutathione-regulated potassium exporter activity
AM474_RS23685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM474_RS23700	COG3609	addiction module antidote protein, CC2985 family
AM474_RS23790	COG1051	belongs to the nudix hydrolase family
AM474_RS23810	COG3188	usher protein
AM474_RS23815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM474_RS23870	COG0425	Belongs to the sulfur carrier protein TusA family
AM474_RS23880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM474_RS23895	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AM474_RS23900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM474_RS23930	COG0183	Belongs to the thiolase family
AM474_RS23940	COG2030	dehydratase
AM474_RS23945	COG2814	Major facilitator Superfamily
AM474_RS23955	COG1960	acyl-CoA dehydrogenase activity
AM474_RS23960	COG1024	Enoyl-CoA hydratase
AM474_RS23965	COG1960	acyl-CoA dehydrogenase activity
AM474_RS23970	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS23995	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS24000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS24025	COG0625	glutathione transferase activity
AM474_RS24030	COG0653	protein targeting
AM474_RS24045	COG2860	membrane
AM474_RS24085	COG1199	ATP-dependent helicase activity
AM474_RS24100	COG2885	chlorophyll binding
AM474_RS24110	COG3835	regulator
AM474_RS24115	COG2610	gluconate transmembrane transporter activity
AM474_RS24120	COG1929	Belongs to the glycerate kinase type-1 family
AM474_RS24130	COG3133	Outer membrane lipoprotein
AM474_RS24140	COG2111	Na H antiporter
AM474_RS24140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM474_RS24145	COG1006	Multisubunit Na H antiporter MnhC subunit
AM474_RS24150	COG0651	ATP synthesis coupled electron transport
AM474_RS24155	COG1863	multisubunit Na H antiporter MnhE subunit
AM474_RS24160	COG2212	antiporter activity
AM474_RS24175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM474_RS24195	COG3189	MarR family transcriptional regulator
AM474_RS24210	COG0326	Molecular chaperone. Has ATPase activity
AM474_RS24260	COG1815	bacterial-type flagellum-dependent cell motility
AM474_RS24270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AM474_RS24280	COG4787	bacterial-type flagellum-dependent cell motility
AM474_RS24325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM474_RS24330	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS24355	COG0438	transferase activity, transferring glycosyl groups
AM474_RS24355	COG1216	Glycosyl transferase, family 2
AM474_RS24360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM474_RS24370	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AM474_RS24375	COG1516	flagellar protein fliS
AM474_RS24430	COG2882	bacterial-type flagellum organization
AM474_RS24445	COG0477	Major facilitator Superfamily
AM474_RS24450	COG2207	Transcriptional regulator
AM474_RS24465	COG2133	pyrroloquinoline quinone binding
AM474_RS24470	COG4628	conserved protein (DUF2132)
AM474_RS24485	COG1132	(ABC) transporter
AM474_RS24515	COG2885	chlorophyll binding
AM474_RS24520	COG2199	diguanylate cyclase activity
AM474_RS24530	COG0242	peptide deformylase activity
AM474_RS24560	COG0667	Aldo Keto reductase
AM474_RS24565	COG0583	DNA-binding transcription factor activity
AM474_RS24605	COG2197	response regulator
AM474_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS24610	COG3321	synthase
AM474_RS24610	COG0604	alcohol dehydrogenase
AM474_RS24625	COG3257	ureidoglycine aminohydrolase activity
AM474_RS24630	COG0583	DNA-binding transcription factor activity
AM474_RS24660	COG0531	amino acid
AM474_RS24670	COG3328	transposase activity
AM474_RS24690	COG3328	transposase activity
AM474_RS24710	COG1943	Transposase
AM474_RS24715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM474_RS24720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM474_RS24720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM474_RS24725	COG0745	RESPONSE REGULATOR receiver
AM474_RS24730	COG2205	protein histidine kinase activity
AM474_RS24745	COG2226	methyltransferase
AM474_RS24760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM474_RS24765	COG2977	Belongs to the P-Pant transferase superfamily
AM474_RS24785	COG0753	catalase activity
AM474_RS24790	COG0861	Integral membrane protein TerC family
AM474_RS24795	COG2951	lytic endotransglycosylase activity
AM474_RS24800	COG3005	denitrification pathway
AM474_RS24805	COG3043	anaerobic respiration
AM474_RS24815	COG3062	negative regulation of establishment of protein localization
AM474_RS24820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM474_RS24820	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM474_RS24825	COG4459	periplasmic nitrate reductase
AM474_RS24845	COG5001	Diguanylate cyclase
AM474_RS24845	COG3447	MASE1 domain protein
AM474_RS24845	COG5002	protein histidine kinase activity
AM474_RS24870	COG0625	glutathione transferase activity
AM474_RS24880	COG1960	acyl-CoA dehydrogenase activity
AM474_RS24885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM474_RS24945	COG2818	Glycosylase
AM474_RS24960	COG3829	transcription factor binding
AM474_RS24970	COG0791	NLP P60 protein
AM474_RS24975	COG0791	NLP P60 protein
AM474_RS24985	COG0583	DNA-binding transcription factor activity
AM474_RS24990	COG1335	isochorismatase
AM474_RS25040	COG2211	Major facilitator Superfamily
AM474_RS25050	COG0367	asparagine synthase
AM474_RS25055	COG0318	PFAM AMP-dependent synthetase and ligase
AM474_RS25065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM474_RS25090	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM474_RS25100	COG0583	DNA-binding transcription factor activity
AM474_RS25105	COG2957	Belongs to the agmatine deiminase family
AM474_RS25120	COG2957	Belongs to the agmatine deiminase family
AM474_RS25125	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM474_RS25145	COG2207	Transcriptional regulator
AM474_RS25160	COG1289	transmembrane transporter activity
AM474_RS25215	COG4191	Histidine kinase
AM474_RS25215	COG0784	Response regulator, receiver
AM474_RS25240	COG1857	crispr-associated protein
AM474_RS25255	COG1518	maintenance of DNA repeat elements
AM474_RS25260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM474_RS25320	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS25325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM474_RS25335	COG1126	abc transporter atp-binding protein
AM474_RS25345	COG0765	amino acid transport
AM474_RS25365	COG0477	Major facilitator Superfamily
AM474_RS25400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS25410	COG1802	Transcriptional regulator
AM474_RS25420	COG4206	TonB-dependent receptor
AM474_RS25435	COG0778	Nitroreductase
AM474_RS25465	COG0406	alpha-ribazole phosphatase activity
AM474_RS25485	COG1960	acyl-CoA dehydrogenase activity
AM474_RS25545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM474_RS25550	COG1230	cation diffusion facilitator family transporter
AM474_RS25565	COG1595	DNA-templated transcription, initiation
AM474_RS25570	COG3712	iron ion homeostasis
AM474_RS25600	COG0121	glutamine amidotransferase
AM474_RS25610	COG0583	DNA-binding transcription factor activity
AM474_RS25630	COG2814	Major facilitator Superfamily
AM474_RS25680	COG4774	siderophore transport
AM474_RS25695	COG4319	ketosteroid isomerase
AM474_RS25700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM474_RS25705	COG3591	Belongs to the peptidase S1B family
AM474_RS25705	COG1864	DNA RNA non-specific endonuclease
AM474_RS25710	COG0583	DNA-binding transcription factor activity
AM474_RS25720	COG0300	oxidoreductase activity
AM474_RS25725	COG1253	flavin adenine dinucleotide binding
AM474_RS25745	COG1902	pentaerythritol trinitrate reductase activity
AM474_RS25770	COG1126	abc transporter atp-binding protein
AM474_RS25775	COG0765	amino acid transport
AM474_RS25780	COG0765	amino acid transport
AM474_RS25795	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS25800	COG0189	ligase activity
AM474_RS25805	COG1982	Orn Lys Arg decarboxylase major
AM474_RS25810	COG2197	response regulator
AM474_RS25820	COG3795	YCII-related domain
AM474_RS25830	COG4941	Belongs to the sigma-70 factor family
AM474_RS25835	COG2814	Major facilitator Superfamily
AM474_RS25845	COG3795	YCII-related domain
AM474_RS25860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM474_RS25875	COG5006	permease, DMT superfamily
AM474_RS25905	COG0384	phenazine biosynthesis protein PhzF
AM474_RS25910	COG2020	methyltransferase activity
AM474_RS25915	COG3634	alkyl hydroperoxide reductase activity
AM474_RS25920	COG1309	transcriptional regulator
AM474_RS25935	COG4221	oxidoreductase activity
AM474_RS25940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS25975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM474_RS25995	COG1247	-acetyltransferase
AM474_RS26015	COG4221	oxidoreductase activity
AM474_RS26020	COG2207	Transcriptional regulator
AM474_RS26055	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AM474_RS26080	COG0210	DNA helicase
AM474_RS26090	COG0116	Belongs to the methyltransferase superfamily
AM474_RS26090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM474_RS26095	COG1196	nuclear chromosome segregation
AM474_RS26095	COG3264	Mechanosensitive ion channel
AM474_RS26110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM474_RS26125	COG0583	DNA-binding transcription factor activity
AM474_RS26135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM474_RS26190	COG0488	(ABC) transporter
AM474_RS26230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM474_RS26240	COG0789	Transcriptional regulator
AM474_RS26285	COG5001	Diguanylate cyclase
AM474_RS26285	COG3300	MHYT domain
AM474_RS26295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS26300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS26315	COG2832	Protein of unknown function (DUF454)
AM474_RS26355	COG1987	bacterial-type flagellum assembly
AM474_RS26375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM474_RS26380	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM474_RS26410	COG0784	Response regulator, receiver
AM474_RS26410	COG2198	Histidine kinase
AM474_RS26410	COG0643	Histidine kinase
AM474_RS26420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AM474_RS26425	COG1360	Flagellar Motor Protein
AM474_RS26430	COG1192	Involved in chromosome partitioning
AM474_RS26440	COG0835	chemotaxis
AM474_RS26465	COG1496	oxidoreductase activity
AM474_RS26470	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS26480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM474_RS26555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM474_RS26560	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM474_RS26575	COG3192	ethanolamine utilization protein
AM474_RS26585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM474_RS26600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM474_RS26605	COG4413	Urea transporter
AM474_RS26610	COG0469	pyruvate kinase activity
AM474_RS26620	COG2084	Dehydrogenase
AM474_RS26625	COG3622	Belongs to the hyi family
AM474_RS26630	COG3960	tartronate-semialdehyde synthase activity
AM474_RS26640	COG1309	transcriptional regulator
AM474_RS26655	COG2233	PERMEase
AM474_RS26715	COG2252	PERMEase
AM474_RS26730	COG0402	S-adenosylhomocysteine deaminase activity
AM474_RS26760	COG1196	nuclear chromosome segregation
AM474_RS26790	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM474_RS26805	COG1960	acyl-CoA dehydrogenase activity
AM474_RS26835	COG2076	Multidrug Resistance protein
AM474_RS26875	COG2217	Heavy metal translocating P-type atpase
AM474_RS26885	COG0348	domain, Protein
AM474_RS26895	COG2010	Cytochrome c
AM474_RS26910	COG3278	Belongs to the heme-copper respiratory oxidase family
AM474_RS26915	COG2010	Cytochrome c
AM474_RS26930	COG3278	Belongs to the heme-copper respiratory oxidase family
AM474_RS26935	COG2010	Cytochrome c
AM474_RS26950	COG3278	Belongs to the heme-copper respiratory oxidase family
AM474_RS26965	COG0840	transmembrane signaling receptor activity
AM474_RS26985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS26990	COG0174	glutamine synthetase
AM474_RS27000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS27005	COG0251	oxidation-reduction process
AM474_RS27035	COG3738	Protein conserved in bacteria
AM474_RS27050	COG2084	Dehydrogenase
AM474_RS27080	COG2009	succinate dehydrogenase
AM474_RS27085	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM474_RS27090	COG1053	succinate dehydrogenase
AM474_RS27095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM474_RS27170	COG2207	Transcriptional regulator
AM474_RS27175	COG2010	Cytochrome c
AM474_RS27175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM474_RS27180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM474_RS27180	COG2010	Cytochrome c
AM474_RS27185	COG2080	2 iron, 2 sulfur cluster binding
AM474_RS27190	COG1846	Transcriptional regulator
AM474_RS27230	COG2205	protein histidine kinase activity
AM474_RS27230	COG0784	Response regulator, receiver
AM474_RS27230	COG5002	protein histidine kinase activity
AM474_RS27260	COG1022	Amp-dependent synthetase and ligase
AM474_RS27290	COG0625	glutathione transferase activity
AM474_RS27300	COG0628	permease
AM474_RS27305	COG2807	transmembrane transport
AM474_RS27310	COG2186	Transcriptional regulator
AM474_RS27315	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM474_RS27320	COG1024	Enoyl-CoA hydratase
AM474_RS27330	COG1960	acyl-CoA dehydrogenase activity
AM474_RS27355	COG2205	protein histidine kinase activity
AM474_RS27360	COG0745	RESPONSE REGULATOR receiver
AM474_RS27400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM474_RS27410	COG0840	transmembrane signaling receptor activity
AM474_RS27425	COG2130	NADP-dependent
AM474_RS27440	COG3135	benzoate transporter
AM474_RS27455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM474_RS27460	COG0625	glutathione transferase activity
AM474_RS27470	COG3209	COG3209 Rhs family protein
AM474_RS27530	COG2204	response regulator
AM474_RS27570	COG0515	serine threonine protein kinase
AM474_RS27570	COG2815	serine threonine protein kinase
AM474_RS27590	COG2840	Smr protein MutS2
AM474_RS27670	COG4792	protein secretion
AM474_RS27675	COG4791	protein targeting
AM474_RS27680	COG4794	Type iii secretion
AM474_RS27685	COG4790	Type iii secretion
AM474_RS27735	COG4789	Type iii secretion
AM474_RS27845	COG1317	bacterial-type flagellum organization
AM474_RS27865	COG0505	Belongs to the CarA family
AM474_RS27875	COG2308	Evidence 4 Homologs of previously reported genes of
AM474_RS27885	COG1305	Transglutaminase-like
AM474_RS27905	COG0183	Belongs to the thiolase family
AM474_RS27920	COG0667	Aldo Keto reductase
AM474_RS27935	COG0519	Catalyzes the synthesis of GMP from XMP
AM474_RS27990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM474_RS28025	COG2909	trisaccharide binding
AM474_RS28030	COG2909	trisaccharide binding
AM474_RS28075	COG4067	protein conserved in archaea
AM474_RS28075	COG0189	ligase activity
AM474_RS28115	COG0668	transmembrane transport
AM474_RS28135	COG0243	molybdopterin cofactor binding
AM474_RS28140	COG2146	nitrite reductase [NAD(P)H] activity
AM474_RS28145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM474_RS28150	COG0515	serine threonine protein kinase
AM474_RS28155	COG2223	nitrite transmembrane transporter activity
AM474_RS28165	COG2201	protein-glutamate methylesterase activity
AM474_RS28190	COG0589	response to stress
AM474_RS28210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM474_RS28255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM474_RS28260	COG2205	protein histidine kinase activity
AM474_RS28265	COG0745	RESPONSE REGULATOR receiver
AM474_RS28290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM474_RS28305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM474_RS28315	COG4172	Belongs to the ABC transporter superfamily
AM474_RS28320	COG4239	(ABC) transporter, permease
AM474_RS28325	COG4174	ABC transporter (Permease)
AM474_RS28330	COG4166	transmembrane transport
AM474_RS28335	COG4166	transmembrane transport
AM474_RS28340	COG0741	lytic transglycosylase activity
AM474_RS28340	COG1388	LysM domain
AM474_RS28360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM474_RS28375	COG0531	amino acid
AM474_RS28385	COG1024	Enoyl-CoA hydratase
AM474_RS28410	COG0583	DNA-binding transcription factor activity
AM474_RS28415	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS28420	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS28440	COG0616	signal peptide processing
AM474_RS28445	COG0604	alcohol dehydrogenase
AM474_RS28470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM474_RS28535	COG3813	Protein conserved in bacteria
AM474_RS28540	COG4977	sequence-specific DNA binding
AM474_RS28545	COG2203	Gaf domain
AM474_RS28545	COG3706	GGDEF domain
AM474_RS28545	COG4251	negative regulation of phosphorylation
AM474_RS28545	COG5001	Diguanylate cyclase
AM474_RS28560	COG2239	Acts as a magnesium transporter
AM474_RS28570	COG3278	Belongs to the heme-copper respiratory oxidase family
AM474_RS28575	COG2354	Protein conserved in bacteria
AM474_RS28580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM474_RS28590	COG0583	DNA-binding transcription factor activity
AM474_RS28595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM474_RS28615	COG1309	transcriptional regulator
AM474_RS28685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS28730	COG0417	DNA replication proofreading
AM474_RS28750	COG0625	glutathione transferase activity
AM474_RS28765	COG2366	antibiotic biosynthetic process
AM474_RS28790	COG2197	response regulator
AM474_RS28840	COG2814	Major facilitator Superfamily
AM474_RS28860	COG3712	iron ion homeostasis
AM474_RS28865	COG1595	DNA-templated transcription, initiation
AM474_RS28900	COG0579	oxidoreductase
AM474_RS28915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM474_RS28915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM474_RS28920	COG0275	rRNA processing
AM474_RS28925	COG4771	TonB-dependent receptor
AM474_RS28945	COG1944	ATP diphosphatase activity
AM474_RS28970	COG2080	2 iron, 2 sulfur cluster binding
AM474_RS28975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AM474_RS28980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM474_RS29010	COG0753	catalase activity
AM474_RS29015	COG2010	Cytochrome c
AM474_RS29035	COG2204	response regulator
AM474_RS29045	COG1129	ABC transporter
AM474_RS29050	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM474_RS29055	COG1609	Transcriptional regulator
AM474_RS29060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM474_RS29110	COG1278	Cold shock
AM474_RS29115	COG0583	DNA-binding transcription factor activity
AM474_RS29130	COG0488	(ABC) transporter
AM474_RS29175	COG2194	sulfuric ester hydrolase activity
AM474_RS29195	COG2205	protein histidine kinase activity
AM474_RS29195	COG0784	Response regulator, receiver
AM474_RS29210	COG3851	Histidine kinase
AM474_RS29275	COG2205	protein histidine kinase activity
AM474_RS29295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM474_RS29300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM474_RS29305	COG0583	DNA-binding transcription factor activity
AM474_RS29310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM474_RS29325	COG2031	fatty acid transporter
AM474_RS29330	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS29335	COG2610	gluconate transmembrane transporter activity
AM474_RS29340	COG3290	protein histidine kinase activity
AM474_RS29340	COG3829	transcription factor binding
AM474_RS29345	COG2271	Major facilitator Superfamily
AM474_RS29355	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM474_RS29385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM474_RS29390	COG1960	acyl-CoA dehydrogenase activity
AM474_RS29395	COG0789	Transcriptional regulator
AM474_RS29400	COG3204	pilus organization
AM474_RS29410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS29415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS29420	COG1309	transcriptional regulator
AM474_RS29460	COG1522	sequence-specific DNA binding
AM474_RS29480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM474_RS29495	COG0028	Belongs to the TPP enzyme family
AM474_RS29510	COG0174	glutamine synthetase
AM474_RS29515	COG0531	amino acid
AM474_RS29530	COG0564	pseudouridine synthase activity
AM474_RS29550	COG2207	Transcriptional regulator
AM474_RS29565	COG1595	DNA-templated transcription, initiation
AM474_RS29585	COG0583	DNA-binding transcription factor activity
AM474_RS29600	COG4771	TonB-dependent receptor
AM474_RS29610	COG4174	ABC transporter (Permease)
AM474_RS29615	COG4239	(ABC) transporter, permease
AM474_RS29620	COG4172	Belongs to the ABC transporter superfamily
AM474_RS29625	COG1104	cysteine desulfurase activity
AM474_RS29660	COG2814	Major facilitator Superfamily
AM474_RS29665	COG2192	nodulation
AM474_RS29685	COG5001	Diguanylate cyclase
AM474_RS29690	COG3153	acetyltransferase
AM474_RS29690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM474_RS29710	COG2010	Cytochrome c
AM474_RS29715	COG2010	Cytochrome c
AM474_RS29725	COG1113	amino acid transport
AM474_RS29745	COG1522	sequence-specific DNA binding
AM474_RS29755	COG0367	asparagine synthase
AM474_RS29760	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM474_RS29765	COG0596	Alpha beta hydrolase
AM474_RS29785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM474_RS29795	COG2814	Major facilitator Superfamily
AM474_RS29830	COG0300	oxidoreductase activity
AM474_RS29840	COG0028	Belongs to the TPP enzyme family
AM474_RS29850	COG1984	allophanate hydrolase subunit 2
AM474_RS29870	COG2814	Major facilitator Superfamily
AM474_RS29875	COG0583	DNA-binding transcription factor activity
AM474_RS29895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM474_RS29895	COG2169	Transcriptional regulator
AM474_RS29930	COG0583	DNA-binding transcription factor activity
AM474_RS29940	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS29945	COG1475	DNA binding
AM474_RS29955	COG3969	phosphoadenosine phosphosulfate
AM474_RS29965	COG3121	Chaperone
AM474_RS29970	COG3188	usher protein
AM474_RS29980	COG3121	Chaperone
AM474_RS30000	COG2323	membrane
AM474_RS30030	COG1546	Belongs to the CinA family
AM474_RS30035	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS30050	COG0058	SHG alpha-glucan phosphorylase activity
AM474_RS30075	COG1285	pathogenesis
AM474_RS30095	COG0366	Alpha amylase catalytic
AM474_RS30105	COG0392	lysyltransferase activity
AM474_RS30110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM474_RS30115	COG3568	Endonuclease Exonuclease Phosphatase
AM474_RS30160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM474_RS30230	COG4191	Histidine kinase
AM474_RS30230	COG0784	Response regulator, receiver
AM474_RS30245	COG2890	protein-(glutamine-N5) methyltransferase activity
AM474_RS30280	COG0517	IMP dehydrogenase activity
AM474_RS30285	COG0366	Alpha amylase catalytic
AM474_RS30305	COG1309	transcriptional regulator
AM474_RS30310	COG2130	NADP-dependent
AM474_RS30320	COG2084	Dehydrogenase
AM474_RS30335	COG0765	amino acid transport
AM474_RS30340	COG0765	amino acid transport
AM474_RS30375	COG2271	Major facilitator Superfamily
AM474_RS30380	COG3618	amidohydrolase
AM474_RS30395	COG2271	Major facilitator Superfamily
AM474_RS30400	COG4948	Mandelate Racemase Muconate Lactonizing
AM474_RS30410	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS30415	COG2995	paraquat-inducible protein a
AM474_RS30420	COG3008	intermembrane lipid transfer
AM474_RS30450	COG1028	Short-chain dehydrogenase reductase Sdr
AM474_RS30460	COG3162	membrane
AM474_RS30465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM474_RS30480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM474_RS30485	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS30490	COG0531	amino acid
AM474_RS30505	COG2072	flavoprotein involved in K transport
AM474_RS30520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS30540	COG2409	Drug exporters of the RND superfamily
AM474_RS30545	COG4447	cellulose binding
AM474_RS30555	COG2508	Transcriptional regulator
AM474_RS30690	COG4644	lycopene metabolic process
AM474_RS30750	COG2258	MOSC domain
AM474_RS30815	COG0728	peptidoglycan biosynthetic process
AM474_RS30825	COG1053	succinate dehydrogenase
AM474_RS30870	COG1115	amino acid carrier protein
AM474_RS30875	COG0252	asparaginase activity
AM474_RS30910	COG1609	Transcriptional regulator
AM474_RS30920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM474_RS30955	COG2329	Antibiotic biosynthesis monooxygenase
AM474_RS30965	COG1309	transcriptional regulator
AM474_RS30990	COG1064	alcohol dehydrogenase
AM474_RS30995	COG2207	Transcriptional regulator
AM474_RS31000	COG0640	Transcriptional regulator
AM474_RS31010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM474_RS31015	COG0431	NADPH-dependent FMN reductase
AM474_RS31060	COG4772	TonB-dependent receptor
AM474_RS31100	COG1053	succinate dehydrogenase
AM474_RS31105	COG2188	Transcriptional regulator
AM474_RS31110	COG3469	chitinase activity
AM474_RS31120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM474_RS31120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM474_RS31145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM474_RS31150	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM474_RS31160	COG2175	clavaminate synthase activity
AM474_RS31170	COG1396	sequence-specific DNA binding
AM474_RS31190	COG0583	DNA-binding transcription factor activity
AM474_RS31195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM474_RS31205	COG1609	Transcriptional regulator
AM474_RS31210	COG3265	gluconokinase activity
AM474_RS31225	COG1012	belongs to the aldehyde dehydrogenase family
AM474_RS31245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM474_RS31250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM474_RS31255	COG1116	anion transmembrane transporter activity
AM474_RS31270	COG4977	sequence-specific DNA binding
AM474_RS31270	COG1917	Cupin 2, conserved barrel domain protein
AM474_RS31285	COG1175	transmembrane transport
AM474_RS31300	COG0246	Mannitol dehydrogenase
AM474_RS31305	COG1070	Carbohydrate kinase
AM474_RS31310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM474_RS31335	COG1464	Belongs to the NlpA lipoprotein family
AM474_RS31345	COG2011	ABC-type metal ion transport system permease component
AM474_RS31350	COG0584	glycerophosphoryl diester phosphodiesterase
AM474_RS31355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM474_RS31360	COG3829	transcription factor binding
AM474_RS31385	COG3829	transcription factor binding
AM474_RS31475	COG4566	intracellular signal transduction
AM474_RS31505	COG1304	FMN binding
AM474_RS31515	COG0735	belongs to the Fur family
AM474_RS31540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM474_RS31585	COG4774	siderophore transport
AM474_RS31590	COG0657	acetylesterase activity
AM474_RS31630	COG1121	(ABC) transporter
AM474_RS31635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM474_RS31675	COG0583	DNA-binding transcription factor activity
AM474_RS31685	COG1335	isochorismatase
AM474_RS31740	COG1566	PFAM secretion protein HlyD family protein
AM474_RS31760	COG0583	DNA-binding transcription factor activity
AM474_RS31775	COG2217	Heavy metal translocating P-type atpase
AM474_RS31810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM474_RS31815	COG1760	l-serine dehydratase
AM474_RS31840	COG0583	DNA-binding transcription factor activity
AM474_RS31860	COG2382	esterase
AM474_RS31870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM474_RS31950	COG3328	transposase activity
AM474_RS31980	COG3712	iron ion homeostasis
AM474_RS31985	COG1595	DNA-templated transcription, initiation
AM474_RS31990	COG0583	DNA-binding transcription factor activity
AM474_RS32010	COG0625	glutathione transferase activity
AM474_RS32045	COG0642	Histidine kinase
AM474_RS32055	COG3258	Cytochrome c
AM474_RS32060	COG2863	cytochrome
AM474_RS32065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM474_RS32130	COG2318	DinB family
AM474_RS32145	COG0590	tRNA wobble adenosine to inosine editing
AM474_RS32150	COG2807	transmembrane transport
AM474_RS32185	COG3485	protocatechuate 3,4-dioxygenase
AM474_RS32195	COG4948	Mandelate Racemase Muconate Lactonizing
AM474_RS32220	COG4638	Rieske (2fe-2S)
AM474_RS32225	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM474_RS32230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM474_RS32230	COG0543	2 iron, 2 sulfur cluster binding
AM474_RS32290	COG1538	Outer membrane efflux protein
AM474_RS32295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS32300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM474_RS32330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM474_RS32340	COG1115	amino acid carrier protein
AM474_RS32350	COG0667	Aldo Keto reductase
AM474_RS32355	COG4589	Belongs to the CDS family
AM474_RS32370	COG2453	phosphatase
AM474_RS32370	COG0671	phosphoesterase, PA-phosphatase related
AM474_RS32375	COG2267	carboxylic ester hydrolase activity
AM474_RS32380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family