locus-tag	class	description
HR116_RS00035	COG2010	Cytochrome c
HR116_RS00050	COG2818	Glycosylase
HR116_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HR116_RS00080	COG0569	domain protein
HR116_RS00100	COG1652	LysM domain
HR116_RS00105	COG0758	DNA mediated transformation
HR116_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HR116_RS00155	COG3119	arylsulfatase activity
HR116_RS00160	COG0583	DNA-binding transcription factor activity
HR116_RS00195	COG3360	Dodecin
HR116_RS00240	COG3174	membrane
HR116_RS00285	COG0367	asparagine synthase
HR116_RS00315	COG0583	DNA-binding transcription factor activity
HR116_RS00330	COG1764	response to oxidative stress
HR116_RS00365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HR116_RS00370	COG0339	signal peptide processing
HR116_RS00375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HR116_RS00390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HR116_RS00405	COG0515	serine threonine protein kinase
HR116_RS00405	COG2815	serine threonine protein kinase
HR116_RS00410	COG0631	protein serine/threonine phosphatase activity
HR116_RS00425	COG1360	Flagellar Motor Protein
HR116_RS00490	COG3501	Rhs element vgr protein
HR116_RS00510	COG3501	Rhs element vgr protein
HR116_RS00550	COG0659	secondary active sulfate transmembrane transporter activity
HR116_RS00560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HR116_RS00565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HR116_RS00570	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HR116_RS00610	COG2153	protein acetylation
HR116_RS00650	COG0583	DNA-binding transcription factor activity
HR116_RS00675	COG2824	Alkylphosphonate utilization operon protein PhnA
HR116_RS00705	COG0402	S-adenosylhomocysteine deaminase activity
HR116_RS00790	COG0583	DNA-binding transcription factor activity
HR116_RS00795	COG3485	protocatechuate 3,4-dioxygenase
HR116_RS00800	COG3485	protocatechuate 3,4-dioxygenase
HR116_RS00805	COG1414	Transcriptional regulator
HR116_RS00820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS00825	COG0583	DNA-binding transcription factor activity
HR116_RS00860	COG2233	PERMEase
HR116_RS00865	COG1309	transcriptional regulator
HR116_RS00900	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HR116_RS00915	COG0835	chemotaxis
HR116_RS00920	COG2198	Histidine kinase
HR116_RS00920	COG0643	Histidine kinase
HR116_RS00925	COG0745	RESPONSE REGULATOR receiver
HR116_RS00935	COG0583	DNA-binding transcription factor activity
HR116_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS00950	COG1116	anion transmembrane transporter activity
HR116_RS00955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS00960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS01000	COG2175	clavaminate synthase activity
HR116_RS01045	COG0154	amidase activity
HR116_RS01055	COG1177	transmembrane transport
HR116_RS01060	COG1176	ABC-type spermidine putrescine transport system, permease component I
HR116_RS01070	COG0583	DNA-binding transcription factor activity
HR116_RS01105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HR116_RS01135	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS01140	COG1113	amino acid transport
HR116_RS01155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HR116_RS01160	COG0235	Class ii aldolase
HR116_RS01165	COG1396	sequence-specific DNA binding
HR116_RS01170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HR116_RS01175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HR116_RS01185	COG0477	Major facilitator Superfamily
HR116_RS01195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HR116_RS01200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HR116_RS01205	COG0583	DNA-binding transcription factor activity
HR116_RS01225	COG0673	inositol 2-dehydrogenase activity
HR116_RS01245	COG2271	Major facilitator Superfamily
HR116_RS01255	COG1309	transcriptional regulator
HR116_RS01260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HR116_RS01270	COG0477	Major facilitator Superfamily
HR116_RS01290	COG2239	Acts as a magnesium transporter
HR116_RS01375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HR116_RS01455	COG0582	viral genome integration into host DNA
HR116_RS01480	COG0745	RESPONSE REGULATOR receiver
HR116_RS01490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HR116_RS01505	COG0583	DNA-binding transcription factor activity
HR116_RS01510	COG2807	transmembrane transport
HR116_RS01530	COG0501	Belongs to the peptidase M48B family
HR116_RS01550	COG4208	sulfate ABC transporter
HR116_RS01560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HR116_RS01595	COG3706	GGDEF domain
HR116_RS01620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HR116_RS01625	COG0174	glutamine synthetase
HR116_RS01630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HR116_RS01635	COG0174	glutamine synthetase
HR116_RS01655	COG3842	ATPase activity
HR116_RS01660	COG1176	ABC-type spermidine putrescine transport system, permease component I
HR116_RS01665	COG1177	transmembrane transport
HR116_RS01700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HR116_RS01740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HR116_RS01760	COG4176	ABC-type proline glycine betaine transport system permease component
HR116_RS01765	COG4175	Glycine betaine
HR116_RS01770	COG2986	histidine ammonia-lyase
HR116_RS01785	COG3501	Rhs element vgr protein
HR116_RS01790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HR116_RS01820	COG0251	oxidation-reduction process
HR116_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS01830	COG1051	belongs to the nudix hydrolase family
HR116_RS01860	COG0765	amino acid transport
HR116_RS01865	COG1126	abc transporter atp-binding protein
HR116_RS01875	COG0840	transmembrane signaling receptor activity
HR116_RS01985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HR116_RS02005	COG0281	malic enzyme
HR116_RS02055	COG0070	glutamate synthase
HR116_RS02055	COG0069	glutamate synthase activity
HR116_RS02055	COG0067	glutamate synthase
HR116_RS02060	COG0493	'glutamate synthase
HR116_RS02085	COG2814	Major facilitator Superfamily
HR116_RS02090	COG0583	DNA-binding transcription factor activity
HR116_RS02095	COG1192	Involved in chromosome partitioning
HR116_RS02110	COG2873	o-acetylhomoserine
HR116_RS02115	COG0730	response to heat
HR116_RS02125	COG3264	Mechanosensitive ion channel
HR116_RS02125	COG1196	nuclear chromosome segregation
HR116_RS02135	COG1960	acyl-CoA dehydrogenase activity
HR116_RS02140	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HR116_RS02175	COG0859	PFAM glycosyl transferase family 9
HR116_RS02180	COG0859	PFAM glycosyl transferase family 9
HR116_RS02185	COG0438	transferase activity, transferring glycosyl groups
HR116_RS02210	COG2192	nodulation
HR116_RS02215	COG0438	transferase activity, transferring glycosyl groups
HR116_RS02235	COG1215	transferase activity, transferring glycosyl groups
HR116_RS02260	COG0367	asparagine synthase
HR116_RS02265	COG1960	acyl-CoA dehydrogenase activity
HR116_RS02270	COG1960	acyl-CoA dehydrogenase activity
HR116_RS02280	COG0667	Aldo Keto reductase
HR116_RS02295	COG0583	DNA-binding transcription factor activity
HR116_RS02300	COG1519	Transferase
HR116_RS02310	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS02310	COG0446	pyridine nucleotide-disulphide oxidoreductase
HR116_RS02340	COG0833	amino acid
HR116_RS02345	COG1024	Enoyl-CoA hydratase
HR116_RS02350	COG1960	acyl-CoA dehydrogenase activity
HR116_RS02370	COG2249	NAD(P)H dehydrogenase (quinone) activity
HR116_RS02375	COG1538	Outer membrane efflux protein
HR116_RS02390	COG0494	nUDIX hydrolase
HR116_RS02400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HR116_RS02405	COG3150	esterase
HR116_RS02420	COG3577	Aspartyl protease
HR116_RS02435	COG1988	membrane-bound metal-dependent
HR116_RS02445	COG3830	Belongs to the UPF0237 family
HR116_RS02445	COG0560	Phosphoserine phosphatase
HR116_RS02450	COG5001	Diguanylate cyclase
HR116_RS02450	COG3300	MHYT domain
HR116_RS02500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HR116_RS02500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HR116_RS02505	COG0802	atpase or kinase
HR116_RS02510	COG0860	N-Acetylmuramoyl-L-alanine amidase
HR116_RS02530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HR116_RS02535	COG0330	HflC and HflK could
HR116_RS02540	COG0330	HflC and HflK could
HR116_RS02570	COG0557	exoribonuclease II activity
HR116_RS02600	COG0305	Participates in initiation and elongation during chromosome replication
HR116_RS02610	COG5001	Diguanylate cyclase
HR116_RS02610	COG3300	MHYT domain
HR116_RS02630	COG0668	transmembrane transport
HR116_RS02670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HR116_RS02685	COG0583	DNA-binding transcription factor activity
HR116_RS02715	COG2423	ornithine cyclodeaminase activity
HR116_RS02720	COG4221	oxidoreductase activity
HR116_RS02745	COG0583	DNA-binding transcription factor activity
HR116_RS02755	COG2814	Major facilitator Superfamily
HR116_RS02775	COG1595	DNA-templated transcription, initiation
HR116_RS02780	COG3712	iron ion homeostasis
HR116_RS02840	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HR116_RS02845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HR116_RS02855	COG2193	ferroxidase activity
HR116_RS02860	COG2982	Protein involved in outer membrane biogenesis
HR116_RS02865	COG0789	Transcriptional regulator
HR116_RS02890	COG0443	Heat shock 70 kDa protein
HR116_RS02905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HR116_RS02950	COG0411	ABC transporter
HR116_RS02965	COG0683	leucine binding
HR116_RS02970	COG2095	MarC family integral membrane protein
HR116_RS03055	COG0023	Translation Initiation Factor
HR116_RS03090	COG1272	protein, Hemolysin III
HR116_RS03095	COG4221	oxidoreductase activity
HR116_RS03120	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HR116_RS03145	COG1283	sodium-dependent phosphate transmembrane transporter activity
HR116_RS03155	COG0534	Mate efflux family protein
HR116_RS03165	COG0463	Glycosyl transferase, family 2
HR116_RS03190	COG0446	pyridine nucleotide-disulphide oxidoreductase
HR116_RS03190	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS03195	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HR116_RS03205	COG0437	4 iron, 4 sulfur cluster binding
HR116_RS03210	COG2864	formate dehydrogenase
HR116_RS03225	COG3276	selenocysteine insertion sequence binding
HR116_RS03240	COG0531	amino acid
HR116_RS03280	COG0509	glycine decarboxylation via glycine cleavage system
HR116_RS03310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HR116_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS03340	COG1522	sequence-specific DNA binding
HR116_RS03345	COG0697	spore germination
HR116_RS03365	COG0697	spore germination
HR116_RS03415	COG1620	l-lactate permease
HR116_RS03420	COG2186	Transcriptional regulator
HR116_RS03450	COG0497	DNA recombination
HR116_RS03515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HR116_RS03550	COG0195	Participates in both transcription termination and antitermination
HR116_RS03650	COG4191	Histidine kinase
HR116_RS03665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HR116_RS03685	COG2252	PERMEase
HR116_RS03695	COG2321	neutral zinc metallopeptidase
HR116_RS03705	COG0436	Aminotransferase
HR116_RS03730	COG4771	TonB-dependent receptor
HR116_RS03735	COG3720	iron ion transport
HR116_RS03740	COG4558	Periplasmic binding protein
HR116_RS03745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HR116_RS03780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HR116_RS03790	COG3098	single-species biofilm formation
HR116_RS03805	COG0028	Belongs to the TPP enzyme family
HR116_RS03820	COG1183	phosphatidylcholine synthase activity
HR116_RS03860	COG2995	paraquat-inducible protein a
HR116_RS03865	COG2995	paraquat-inducible protein a
HR116_RS03870	COG3008	intermembrane lipid transfer
HR116_RS03875	COG1178	ABC-type Fe3 transport system permease component
HR116_RS03880	COG1840	ABC-type Fe3 transport system, periplasmic component
HR116_RS03925	COG0456	acetyltransferase
HR116_RS03935	COG0288	reversible hydration of carbon dioxide
HR116_RS03945	COG3549	Plasmid maintenance system killer
HR116_RS03960	COG0012	GTP binding
HR116_RS04015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HR116_RS04035	COG0789	Transcriptional regulator
HR116_RS04045	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HR116_RS04050	COG1090	epimerase
HR116_RS04165	COG1285	pathogenesis
HR116_RS04170	COG2135	peptidase activity
HR116_RS04175	COG0840	transmembrane signaling receptor activity
HR116_RS04180	COG0501	Belongs to the peptidase M48B family
HR116_RS04195	COG2119	membrane
HR116_RS04200	COG0833	amino acid
HR116_RS04210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HR116_RS04245	COG2010	Cytochrome c
HR116_RS04250	COG3608	succinylglutamate desuccinylase aspartoacylase
HR116_RS04250	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HR116_RS04320	COG1966	Carbon starvation protein
HR116_RS04325	COG2879	small protein
HR116_RS04330	COG0523	cobalamin synthesis protein
HR116_RS04355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS04360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS04380	COG0488	(ABC) transporter
HR116_RS04385	COG1136	(ABC) transporter
HR116_RS04385	COG0577	efflux transmembrane transporter activity
HR116_RS04390	COG1136	(ABC) transporter
HR116_RS04390	COG0577	efflux transmembrane transporter activity
HR116_RS04415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HR116_RS04435	COG3541	Predicted nucleotidyltransferase
HR116_RS04440	COG1690	Belongs to the RtcB family
HR116_RS04455	COG4650	regulator
HR116_RS04480	COG1067	ATP-dependent peptidase activity
HR116_RS04500	COG0545	Peptidyl-prolyl cis-trans isomerase
HR116_RS04515	COG0142	geranyltranstransferase activity
HR116_RS04540	COG3045	CreA protein
HR116_RS04555	COG0196	riboflavin kinase activity
HR116_RS04570	COG1047	Peptidyl-prolyl cis-trans
HR116_RS04610	COG4969	Belongs to the N-Me-Phe pilin family
HR116_RS04685	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HR116_RS04690	COG1252	NADH dehydrogenase
HR116_RS04755	COG4969	Belongs to the N-Me-Phe pilin family
HR116_RS04780	COG3023	N-Acetylmuramoyl-L-alanine amidase
HR116_RS04795	COG0019	diaminopimelate decarboxylase activity
HR116_RS04805	COG2194	sulfuric ester hydrolase activity
HR116_RS04820	COG4774	siderophore transport
HR116_RS04825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HR116_RS04845	COG1984	allophanate hydrolase subunit 2
HR116_RS04860	COG4608	Belongs to the ABC transporter superfamily
HR116_RS04865	COG0444	Belongs to the ABC transporter superfamily
HR116_RS04870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HR116_RS04875	COG0601	transmembrane transport
HR116_RS04880	COG0747	negative chemotaxis
HR116_RS04890	COG0747	negative chemotaxis
HR116_RS04905	COG0747	negative chemotaxis
HR116_RS04910	COG0747	negative chemotaxis
HR116_RS04925	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HR116_RS04930	COG4676	Protein conserved in bacteria
HR116_RS04935	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HR116_RS04950	COG5445	Predicted secreted protein (DUF2300)
HR116_RS04955	COG4676	Protein conserved in bacteria
HR116_RS04960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HR116_RS04965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HR116_RS04985	COG1077	Cell shape determining protein MreB Mrl
HR116_RS04990	COG1792	Involved in formation and maintenance of cell shape
HR116_RS05005	COG1530	ribonuclease E activity
HR116_RS05015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HR116_RS05020	COG0312	modulator of DNA gyrase
HR116_RS05030	COG0312	modulator of DNA gyrase
HR116_RS05085	COG1137	ATPase activity
HR116_RS05100	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HR116_RS05110	COG1127	ABC transporter
HR116_RS05115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HR116_RS05120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HR116_RS05160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HR116_RS05170	COG2951	lytic endotransglycosylase activity
HR116_RS05190	COG2945	thiolester hydrolase activity
HR116_RS05200	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HR116_RS05215	COG1960	acyl-CoA dehydrogenase activity
HR116_RS05220	COG0667	Aldo Keto reductase
HR116_RS05235	COG0723	plastoquinol--plastocyanin reductase activity
HR116_RS05240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HR116_RS05245	COG2857	Cytochrome c1
HR116_RS05250	COG0625	glutathione transferase activity
HR116_RS05255	COG2969	positive regulation of protein catabolic process
HR116_RS05260	COG2823	Periplasmic or secreted lipoprotein
HR116_RS05275	COG3107	peptidoglycan biosynthetic process
HR116_RS05315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HR116_RS05330	COG0772	Belongs to the SEDS family
HR116_RS05375	COG0741	lytic transglycosylase activity
HR116_RS05375	COG1196	nuclear chromosome segregation
HR116_RS05375	COG0739	heme binding
HR116_RS05395	COG0494	nUDIX hydrolase
HR116_RS05400	COG2096	Adenosyltransferase
HR116_RS05415	COG0745	RESPONSE REGULATOR receiver
HR116_RS05425	COG0668	transmembrane transport
HR116_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS05460	COG3030	protein affecting phage T7 exclusion by the F plasmid
HR116_RS05495	COG0745	RESPONSE REGULATOR receiver
HR116_RS05500	COG2205	protein histidine kinase activity
HR116_RS05510	COG3642	lipopolysaccharide core region biosynthetic process
HR116_RS05525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS05530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS05555	COG1704	LemA family
HR116_RS05595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HR116_RS05610	COG1918	ferrous iron import across plasma membrane
HR116_RS05625	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS05630	COG2814	Major facilitator Superfamily
HR116_RS05645	COG0589	response to stress
HR116_RS05665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HR116_RS05665	COG0426	domain, Protein
HR116_RS05670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HR116_RS05685	COG1473	amidohydrolase
HR116_RS05695	COG0154	amidase activity
HR116_RS05710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HR116_RS05725	COG0693	protein deglycase activity
HR116_RS05745	COG3706	GGDEF domain
HR116_RS05755	COG1024	Enoyl-CoA hydratase
HR116_RS05765	COG0589	response to stress
HR116_RS05795	COG0714	Associated with various cellular activities
HR116_RS05825	COG2925	Exonuclease
HR116_RS05835	COG0788	formyltetrahydrofolate deformylase activity
HR116_RS05870	COG0433	COG0433 Predicted ATPase
HR116_RS05890	COG4964	Belongs to the GSP D family
HR116_RS05950	COG0306	phosphate transporter
HR116_RS05960	COG0840	transmembrane signaling receptor activity
HR116_RS05975	COG0697	spore germination
HR116_RS05980	COG0095	Lipoate-protein ligase
HR116_RS05985	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HR116_RS05990	COG1074	ATP-dependent DNA helicase activity
HR116_RS05995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HR116_RS06005	COG0420	3'-5' exonuclease activity
HR116_RS06150	COG2831	hemolysin activation secretion protein
HR116_RS06185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HR116_RS06195	COG0583	DNA-binding transcription factor activity
HR116_RS06215	COG0154	amidase activity
HR116_RS06220	COG0463	Glycosyl transferase, family 2
HR116_RS06235	COG0583	DNA-binding transcription factor activity
HR116_RS06410	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HR116_RS06505	COG4695	Portal protein
HR116_RS06585	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HR116_RS06590	COG2910	NAD(P)H-binding
HR116_RS06610	COG1024	Enoyl-CoA hydratase
HR116_RS06615	COG1960	acyl-CoA dehydrogenase activity
HR116_RS06630	COG2720	vancomycin resistance protein
HR116_RS06640	COG3180	Ammonia monooxygenase
HR116_RS06720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HR116_RS06785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HR116_RS06795	COG4206	TonB-dependent receptor
HR116_RS06805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HR116_RS06810	COG0583	DNA-binding transcription factor activity
HR116_RS06840	COG1113	amino acid transport
HR116_RS06855	COG2079	MmgE PrpD family protein
HR116_RS06870	COG0372	Belongs to the citrate synthase family
HR116_RS06880	COG1802	Transcriptional regulator
HR116_RS06890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HR116_RS06915	COG0656	L-ascorbic acid biosynthetic process
HR116_RS06930	COG3023	N-Acetylmuramoyl-L-alanine amidase
HR116_RS06945	COG0546	phosphoglycolate phosphatase activity
HR116_RS06960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HR116_RS07040	COG2267	carboxylic ester hydrolase activity
HR116_RS07055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HR116_RS07060	COG2885	chlorophyll binding
HR116_RS07065	COG0204	Acyl-transferase
HR116_RS07090	COG0386	Belongs to the glutathione peroxidase family
HR116_RS07095	COG1309	transcriptional regulator
HR116_RS07105	COG1307	EDD domain protein, DegV family
HR116_RS07140	COG0450	alkyl hydroperoxide reductase
HR116_RS07145	COG0492	ferredoxin-NADP+ reductase activity
HR116_RS07185	COG0271	Belongs to the BolA IbaG family
HR116_RS07205	COG5002	protein histidine kinase activity
HR116_RS07205	COG5001	Diguanylate cyclase
HR116_RS07215	COG0604	alcohol dehydrogenase
HR116_RS07215	COG3321	synthase
HR116_RS07215	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS07235	COG1113	amino acid transport
HR116_RS07285	COG0583	DNA-binding transcription factor activity
HR116_RS07290	COG0583	DNA-binding transcription factor activity
HR116_RS07295	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HR116_RS07300	COG1960	acyl-CoA dehydrogenase activity
HR116_RS07310	COG2079	MmgE PrpD family protein
HR116_RS07320	COG2301	Belongs to the HpcH HpaI aldolase family
HR116_RS07415	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HR116_RS07485	COG2239	Acts as a magnesium transporter
HR116_RS07495	COG4807	Protein conserved in bacteria
HR116_RS07510	COG3038	cytochrome b561
HR116_RS07560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HR116_RS07565	COG2205	protein histidine kinase activity
HR116_RS07565	COG0784	Response regulator, receiver
HR116_RS07565	COG5002	protein histidine kinase activity
HR116_RS07595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HR116_RS07600	COG3956	TIGRFAM MazG family protein
HR116_RS07610	COG3122	Protein conserved in bacteria
HR116_RS07650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HR116_RS07665	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HR116_RS07700	COG3118	belongs to the thioredoxin family
HR116_RS07745	COG0783	Belongs to the Dps family
HR116_RS07775	COG0824	Thioesterase
HR116_RS07805	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HR116_RS07810	COG0602	queuosine metabolic process
HR116_RS07825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HR116_RS07850	COG3609	addiction module antidote protein, CC2985 family
HR116_RS07960	COG1074	ATP-dependent DNA helicase activity
HR116_RS08120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HR116_RS08145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HR116_RS08155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HR116_RS08290	COG1192	Involved in chromosome partitioning
HR116_RS08310	COG1051	belongs to the nudix hydrolase family
HR116_RS08330	COG3188	usher protein
HR116_RS08335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HR116_RS08390	COG0425	Belongs to the sulfur carrier protein TusA family
HR116_RS08400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HR116_RS08415	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HR116_RS08420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HR116_RS08450	COG0183	Belongs to the thiolase family
HR116_RS08460	COG2030	dehydratase
HR116_RS08465	COG2814	Major facilitator Superfamily
HR116_RS08475	COG1960	acyl-CoA dehydrogenase activity
HR116_RS08480	COG1024	Enoyl-CoA hydratase
HR116_RS08485	COG1960	acyl-CoA dehydrogenase activity
HR116_RS08490	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS08515	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS08520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS08545	COG0625	glutathione transferase activity
HR116_RS08550	COG0653	protein targeting
HR116_RS08565	COG2860	membrane
HR116_RS08605	COG1199	ATP-dependent helicase activity
HR116_RS08620	COG2885	chlorophyll binding
HR116_RS08630	COG3835	regulator
HR116_RS08635	COG2610	gluconate transmembrane transporter activity
HR116_RS08640	COG1929	Belongs to the glycerate kinase type-1 family
HR116_RS08650	COG3133	Outer membrane lipoprotein
HR116_RS08655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HR116_RS08655	COG2111	Na H antiporter
HR116_RS08660	COG1006	Multisubunit Na H antiporter MnhC subunit
HR116_RS08665	COG0651	ATP synthesis coupled electron transport
HR116_RS08675	COG2212	antiporter activity
HR116_RS08690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HR116_RS08710	COG3189	MarR family transcriptional regulator
HR116_RS08725	COG0326	Molecular chaperone. Has ATPase activity
HR116_RS08770	COG1815	bacterial-type flagellum-dependent cell motility
HR116_RS08780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HR116_RS08790	COG4787	bacterial-type flagellum-dependent cell motility
HR116_RS08815	COG1256	bacterial-type flagellum assembly
HR116_RS08835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HR116_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS08865	COG0438	transferase activity, transferring glycosyl groups
HR116_RS08865	COG1216	Glycosyl transferase, family 2
HR116_RS08870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HR116_RS08880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HR116_RS08885	COG1516	flagellar protein fliS
HR116_RS08905	COG4191	Histidine kinase
HR116_RS08940	COG2882	bacterial-type flagellum organization
HR116_RS08955	COG0477	Major facilitator Superfamily
HR116_RS08960	COG2207	Transcriptional regulator
HR116_RS08975	COG2133	pyrroloquinoline quinone binding
HR116_RS08980	COG4628	conserved protein (DUF2132)
HR116_RS08990	COG1132	(ABC) transporter
HR116_RS09020	COG2885	chlorophyll binding
HR116_RS09025	COG2199	diguanylate cyclase activity
HR116_RS09035	COG0242	peptide deformylase activity
HR116_RS09060	COG0667	Aldo Keto reductase
HR116_RS09065	COG0583	DNA-binding transcription factor activity
HR116_RS09105	COG2197	response regulator
HR116_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS09110	COG0604	alcohol dehydrogenase
HR116_RS09110	COG3321	synthase
HR116_RS09125	COG3257	ureidoglycine aminohydrolase activity
HR116_RS09130	COG0583	DNA-binding transcription factor activity
HR116_RS09160	COG0531	amino acid
HR116_RS09180	COG4104	PAAR repeat-containing protein
HR116_RS09200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HR116_RS09205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HR116_RS09205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HR116_RS09210	COG0745	RESPONSE REGULATOR receiver
HR116_RS09215	COG2205	protein histidine kinase activity
HR116_RS09230	COG2226	methyltransferase
HR116_RS09245	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HR116_RS09250	COG2977	Belongs to the P-Pant transferase superfamily
HR116_RS09270	COG0753	catalase activity
HR116_RS09275	COG0861	Integral membrane protein TerC family
HR116_RS09280	COG2951	lytic endotransglycosylase activity
HR116_RS09285	COG3005	denitrification pathway
HR116_RS09290	COG3043	anaerobic respiration
HR116_RS09300	COG3062	negative regulation of establishment of protein localization
HR116_RS09305	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HR116_RS09305	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HR116_RS09310	COG4459	periplasmic nitrate reductase
HR116_RS09320	COG0745	RESPONSE REGULATOR receiver
HR116_RS09330	COG3447	MASE1 domain protein
HR116_RS09330	COG5001	Diguanylate cyclase
HR116_RS09330	COG5002	protein histidine kinase activity
HR116_RS09350	COG0625	glutathione transferase activity
HR116_RS09360	COG1960	acyl-CoA dehydrogenase activity
HR116_RS09365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HR116_RS09390	COG2818	Glycosylase
HR116_RS09405	COG3829	transcription factor binding
HR116_RS09415	COG0791	NLP P60 protein
HR116_RS09420	COG0791	NLP P60 protein
HR116_RS09430	COG0583	DNA-binding transcription factor activity
HR116_RS09435	COG1335	isochorismatase
HR116_RS09485	COG2211	Major facilitator Superfamily
HR116_RS09495	COG0367	asparagine synthase
HR116_RS09500	COG0318	PFAM AMP-dependent synthetase and ligase
HR116_RS09510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HR116_RS09535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HR116_RS09545	COG2249	NAD(P)H dehydrogenase (quinone) activity
HR116_RS09550	COG2249	NAD(P)H dehydrogenase (quinone) activity
HR116_RS09570	COG2207	Transcriptional regulator
HR116_RS09585	COG1289	transmembrane transporter activity
HR116_RS09625	COG4191	Histidine kinase
HR116_RS09625	COG0784	Response regulator, receiver
HR116_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS09680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HR116_RS09690	COG1126	abc transporter atp-binding protein
HR116_RS09700	COG0765	amino acid transport
HR116_RS09720	COG0477	Major facilitator Superfamily
HR116_RS09755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS09765	COG1802	Transcriptional regulator
HR116_RS09775	COG4206	TonB-dependent receptor
HR116_RS09790	COG0778	Nitroreductase
HR116_RS09820	COG0406	alpha-ribazole phosphatase activity
HR116_RS09840	COG1960	acyl-CoA dehydrogenase activity
HR116_RS09900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HR116_RS09905	COG1230	cation diffusion facilitator family transporter
HR116_RS09920	COG1595	DNA-templated transcription, initiation
HR116_RS09925	COG3712	iron ion homeostasis
HR116_RS09955	COG0121	glutamine amidotransferase
HR116_RS09965	COG0583	DNA-binding transcription factor activity
HR116_RS09985	COG2814	Major facilitator Superfamily
HR116_RS10030	COG4774	siderophore transport
HR116_RS10045	COG4319	ketosteroid isomerase
HR116_RS10050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HR116_RS10055	COG1864	DNA RNA non-specific endonuclease
HR116_RS10055	COG3591	Belongs to the peptidase S1B family
HR116_RS10060	COG0583	DNA-binding transcription factor activity
HR116_RS10070	COG0300	oxidoreductase activity
HR116_RS10075	COG1253	flavin adenine dinucleotide binding
HR116_RS10090	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS10115	COG1126	abc transporter atp-binding protein
HR116_RS10120	COG0765	amino acid transport
HR116_RS10125	COG0765	amino acid transport
HR116_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS10145	COG0189	ligase activity
HR116_RS10150	COG1982	Orn Lys Arg decarboxylase major
HR116_RS10155	COG2197	response regulator
HR116_RS10165	COG3795	YCII-related domain
HR116_RS10175	COG4941	Belongs to the sigma-70 factor family
HR116_RS10180	COG2814	Major facilitator Superfamily
HR116_RS10190	COG3795	YCII-related domain
HR116_RS10205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HR116_RS10220	COG5006	permease, DMT superfamily
HR116_RS10260	COG0384	phenazine biosynthesis protein PhzF
HR116_RS10285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HR116_RS10300	COG0582	viral genome integration into host DNA
HR116_RS10330	COG1247	-acetyltransferase
HR116_RS10340	COG4221	oxidoreductase activity
HR116_RS10345	COG2207	Transcriptional regulator
HR116_RS10370	COG3501	Rhs element vgr protein
HR116_RS10405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HR116_RS10430	COG0210	DNA helicase
HR116_RS10440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HR116_RS10440	COG0116	Belongs to the methyltransferase superfamily
HR116_RS10445	COG3264	Mechanosensitive ion channel
HR116_RS10445	COG1196	nuclear chromosome segregation
HR116_RS10455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HR116_RS10470	COG0583	DNA-binding transcription factor activity
HR116_RS10475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HR116_RS10560	COG5001	Diguanylate cyclase
HR116_RS10560	COG3300	MHYT domain
HR116_RS10570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS10575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS10590	COG2832	Protein of unknown function (DUF454)
HR116_RS10630	COG1987	bacterial-type flagellum assembly
HR116_RS10650	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HR116_RS10655	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HR116_RS10685	COG0643	Histidine kinase
HR116_RS10685	COG0784	Response regulator, receiver
HR116_RS10685	COG2198	Histidine kinase
HR116_RS10695	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HR116_RS10700	COG1360	Flagellar Motor Protein
HR116_RS10705	COG1192	Involved in chromosome partitioning
HR116_RS10715	COG0835	chemotaxis
HR116_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS10760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HR116_RS10835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HR116_RS10840	COG0446	pyridine nucleotide-disulphide oxidoreductase
HR116_RS10855	COG3192	ethanolamine utilization protein
HR116_RS10865	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HR116_RS10880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HR116_RS10885	COG4413	Urea transporter
HR116_RS10890	COG0469	pyruvate kinase activity
HR116_RS10900	COG2084	Dehydrogenase
HR116_RS10905	COG3622	Belongs to the hyi family
HR116_RS10910	COG3960	tartronate-semialdehyde synthase activity
HR116_RS10920	COG1309	transcriptional regulator
HR116_RS10935	COG2233	PERMEase
HR116_RS11005	COG2252	PERMEase
HR116_RS11015	COG0402	S-adenosylhomocysteine deaminase activity
HR116_RS11045	COG1196	nuclear chromosome segregation
HR116_RS11075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HR116_RS11090	COG1960	acyl-CoA dehydrogenase activity
HR116_RS11120	COG2076	Multidrug Resistance protein
HR116_RS11160	COG2217	Heavy metal translocating P-type atpase
HR116_RS11170	COG0348	domain, Protein
HR116_RS11175	COG2010	Cytochrome c
HR116_RS11190	COG3278	Belongs to the heme-copper respiratory oxidase family
HR116_RS11195	COG2010	Cytochrome c
HR116_RS11210	COG3278	Belongs to the heme-copper respiratory oxidase family
HR116_RS11225	COG0840	transmembrane signaling receptor activity
HR116_RS11245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS11250	COG0174	glutamine synthetase
HR116_RS11260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS11265	COG0251	oxidation-reduction process
HR116_RS11290	COG3738	Protein conserved in bacteria
HR116_RS11305	COG2084	Dehydrogenase
HR116_RS11335	COG2009	succinate dehydrogenase
HR116_RS11340	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HR116_RS11345	COG1053	succinate dehydrogenase
HR116_RS11350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HR116_RS11425	COG2207	Transcriptional regulator
HR116_RS11430	COG2010	Cytochrome c
HR116_RS11430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HR116_RS11435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HR116_RS11435	COG2010	Cytochrome c
HR116_RS11440	COG2080	2 iron, 2 sulfur cluster binding
HR116_RS11445	COG1846	Transcriptional regulator
HR116_RS11485	COG2205	protein histidine kinase activity
HR116_RS11485	COG5002	protein histidine kinase activity
HR116_RS11485	COG0784	Response regulator, receiver
HR116_RS11515	COG1022	Amp-dependent synthetase and ligase
HR116_RS11545	COG0625	glutathione transferase activity
HR116_RS11555	COG0628	permease
HR116_RS11560	COG2807	transmembrane transport
HR116_RS11565	COG2186	Transcriptional regulator
HR116_RS11570	COG1250	3-hydroxyacyl-CoA dehydrogenase
HR116_RS11575	COG1024	Enoyl-CoA hydratase
HR116_RS11585	COG1960	acyl-CoA dehydrogenase activity
HR116_RS11610	COG2205	protein histidine kinase activity
HR116_RS11615	COG0745	RESPONSE REGULATOR receiver
HR116_RS11655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HR116_RS11665	COG0840	transmembrane signaling receptor activity
HR116_RS11675	COG2130	NADP-dependent
HR116_RS11690	COG3135	benzoate transporter
HR116_RS11705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HR116_RS11710	COG0625	glutathione transferase activity
HR116_RS11755	COG2204	response regulator
HR116_RS11795	COG2815	serine threonine protein kinase
HR116_RS11795	COG0515	serine threonine protein kinase
HR116_RS11815	COG2840	Smr protein MutS2
HR116_RS11895	COG4792	protein secretion
HR116_RS11900	COG4791	protein targeting
HR116_RS11905	COG4794	Type iii secretion
HR116_RS11910	COG4790	Type iii secretion
HR116_RS11960	COG4789	Type iii secretion
HR116_RS12070	COG1317	bacterial-type flagellum organization
HR116_RS12090	COG0505	Belongs to the CarA family
HR116_RS12095	COG2308	Evidence 4 Homologs of previously reported genes of
HR116_RS12105	COG1305	Transglutaminase-like
HR116_RS12125	COG0183	Belongs to the thiolase family
HR116_RS12140	COG0667	Aldo Keto reductase
HR116_RS12155	COG0519	Catalyzes the synthesis of GMP from XMP
HR116_RS12205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HR116_RS12240	COG2909	trisaccharide binding
HR116_RS12245	COG2909	trisaccharide binding
HR116_RS12285	COG4067	protein conserved in archaea
HR116_RS12285	COG0189	ligase activity
HR116_RS12320	COG0668	transmembrane transport
HR116_RS12340	COG0243	molybdopterin cofactor binding
HR116_RS12345	COG2146	nitrite reductase [NAD(P)H] activity
HR116_RS12350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HR116_RS12355	COG0515	serine threonine protein kinase
HR116_RS12360	COG2223	nitrite transmembrane transporter activity
HR116_RS12370	COG2201	protein-glutamate methylesterase activity
HR116_RS12390	COG0589	response to stress
HR116_RS12410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HR116_RS12455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HR116_RS12460	COG2205	protein histidine kinase activity
HR116_RS12465	COG0745	RESPONSE REGULATOR receiver
HR116_RS12485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HR116_RS12500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HR116_RS12510	COG4172	Belongs to the ABC transporter superfamily
HR116_RS12515	COG4239	(ABC) transporter, permease
HR116_RS12520	COG4174	ABC transporter (Permease)
HR116_RS12525	COG4166	transmembrane transport
HR116_RS12530	COG4166	transmembrane transport
HR116_RS12535	COG1388	LysM domain
HR116_RS12535	COG0741	lytic transglycosylase activity
HR116_RS12555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HR116_RS12565	COG1982	Orn Lys Arg decarboxylase major
HR116_RS12570	COG0531	amino acid
HR116_RS12580	COG1024	Enoyl-CoA hydratase
HR116_RS12605	COG0583	DNA-binding transcription factor activity
HR116_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS12635	COG0616	signal peptide processing
HR116_RS12640	COG0604	alcohol dehydrogenase
HR116_RS12665	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HR116_RS12725	COG3813	Protein conserved in bacteria
HR116_RS12730	COG4977	sequence-specific DNA binding
HR116_RS12735	COG3706	GGDEF domain
HR116_RS12735	COG2203	Gaf domain
HR116_RS12735	COG4251	negative regulation of phosphorylation
HR116_RS12735	COG5001	Diguanylate cyclase
HR116_RS12750	COG2239	Acts as a magnesium transporter
HR116_RS12760	COG3278	Belongs to the heme-copper respiratory oxidase family
HR116_RS12765	COG2354	Protein conserved in bacteria
HR116_RS12775	COG0583	DNA-binding transcription factor activity
HR116_RS12780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HR116_RS12870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS12915	COG0417	DNA replication proofreading
HR116_RS12935	COG0625	glutathione transferase activity
HR116_RS12950	COG2366	antibiotic biosynthetic process
HR116_RS12975	COG2197	response regulator
HR116_RS13025	COG2814	Major facilitator Superfamily
HR116_RS13045	COG3712	iron ion homeostasis
HR116_RS13050	COG1595	DNA-templated transcription, initiation
HR116_RS13080	COG0579	oxidoreductase
HR116_RS13095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HR116_RS13095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HR116_RS13100	COG0275	rRNA processing
HR116_RS13105	COG4771	TonB-dependent receptor
HR116_RS13125	COG1944	ATP diphosphatase activity
HR116_RS13150	COG2080	2 iron, 2 sulfur cluster binding
HR116_RS13155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HR116_RS13160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HR116_RS13190	COG0753	catalase activity
HR116_RS13195	COG2010	Cytochrome c
HR116_RS13220	COG1129	ABC transporter
HR116_RS13225	COG1172	Belongs to the binding-protein-dependent transport system permease family
HR116_RS13230	COG1609	Transcriptional regulator
HR116_RS13235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HR116_RS13285	COG1278	Cold shock
HR116_RS13290	COG0583	DNA-binding transcription factor activity
HR116_RS13305	COG0488	(ABC) transporter
HR116_RS13345	COG2194	sulfuric ester hydrolase activity
HR116_RS13365	COG2205	protein histidine kinase activity
HR116_RS13365	COG0784	Response regulator, receiver
HR116_RS13385	COG3851	Histidine kinase
HR116_RS13405	COG2010	Cytochrome c
HR116_RS13405	COG4993	Dehydrogenase
HR116_RS13410	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS13450	COG2205	protein histidine kinase activity
HR116_RS13470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HR116_RS13475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HR116_RS13480	COG0583	DNA-binding transcription factor activity
HR116_RS13485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HR116_RS13500	COG2031	fatty acid transporter
HR116_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS13510	COG2610	gluconate transmembrane transporter activity
HR116_RS13515	COG3290	protein histidine kinase activity
HR116_RS13515	COG3829	transcription factor binding
HR116_RS13520	COG2271	Major facilitator Superfamily
HR116_RS13530	COG0179	Fumarylacetoacetate (FAA) hydrolase
HR116_RS13560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HR116_RS13565	COG1960	acyl-CoA dehydrogenase activity
HR116_RS13570	COG0789	Transcriptional regulator
HR116_RS13575	COG3204	pilus organization
HR116_RS13585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS13590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS13595	COG1309	transcriptional regulator
HR116_RS13635	COG1522	sequence-specific DNA binding
HR116_RS13655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HR116_RS13670	COG0028	Belongs to the TPP enzyme family
HR116_RS13695	COG0174	glutamine synthetase
HR116_RS13700	COG0531	amino acid
HR116_RS13710	COG0564	pseudouridine synthase activity
HR116_RS13730	COG2207	Transcriptional regulator
HR116_RS13745	COG1595	DNA-templated transcription, initiation
HR116_RS13765	COG0583	DNA-binding transcription factor activity
HR116_RS13780	COG4771	TonB-dependent receptor
HR116_RS13790	COG4174	ABC transporter (Permease)
HR116_RS13795	COG4239	(ABC) transporter, permease
HR116_RS13800	COG4172	Belongs to the ABC transporter superfamily
HR116_RS13805	COG1104	cysteine desulfurase activity
HR116_RS13835	COG2814	Major facilitator Superfamily
HR116_RS13840	COG2192	nodulation
HR116_RS13845	COG4206	TonB-dependent receptor
HR116_RS13855	COG5001	Diguanylate cyclase
HR116_RS13880	COG2010	Cytochrome c
HR116_RS13885	COG2010	Cytochrome c
HR116_RS13890	COG1113	amino acid transport
HR116_RS13905	COG1522	sequence-specific DNA binding
HR116_RS13915	COG0367	asparagine synthase
HR116_RS13920	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HR116_RS13925	COG0596	Alpha beta hydrolase
HR116_RS13945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HR116_RS13955	COG2814	Major facilitator Superfamily
HR116_RS13990	COG0300	oxidoreductase activity
HR116_RS13995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HR116_RS14015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HR116_RS14020	COG1045	serine acetyltransferase
HR116_RS14025	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HR116_RS14035	COG0028	Belongs to the TPP enzyme family
HR116_RS14045	COG1984	allophanate hydrolase subunit 2
HR116_RS14065	COG2814	Major facilitator Superfamily
HR116_RS14070	COG0583	DNA-binding transcription factor activity
HR116_RS14085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HR116_RS14085	COG2169	Transcriptional regulator
HR116_RS14095	COG1063	alcohol dehydrogenase
HR116_RS14115	COG0583	DNA-binding transcription factor activity
HR116_RS14120	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HR116_RS14125	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS14130	COG1475	DNA binding
HR116_RS14140	COG3969	phosphoadenosine phosphosulfate
HR116_RS14150	COG3121	Chaperone
HR116_RS14155	COG3188	usher protein
HR116_RS14165	COG3121	Chaperone
HR116_RS14185	COG2323	membrane
HR116_RS14215	COG1546	Belongs to the CinA family
HR116_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS14235	COG0058	SHG alpha-glucan phosphorylase activity
HR116_RS14255	COG1285	pathogenesis
HR116_RS14275	COG0366	Alpha amylase catalytic
HR116_RS14285	COG0392	lysyltransferase activity
HR116_RS14290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HR116_RS14295	COG3568	Endonuclease Exonuclease Phosphatase
HR116_RS14335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HR116_RS14370	COG1363	Peptidase, m42
HR116_RS14400	COG0784	Response regulator, receiver
HR116_RS14400	COG4191	Histidine kinase
HR116_RS14415	COG2890	protein-(glutamine-N5) methyltransferase activity
HR116_RS14445	COG0517	IMP dehydrogenase activity
HR116_RS14450	COG0366	Alpha amylase catalytic
HR116_RS14470	COG1309	transcriptional regulator
HR116_RS14475	COG2130	NADP-dependent
HR116_RS14485	COG2084	Dehydrogenase
HR116_RS14500	COG0765	amino acid transport
HR116_RS14505	COG0765	amino acid transport
HR116_RS14540	COG2271	Major facilitator Superfamily
HR116_RS14545	COG3618	amidohydrolase
HR116_RS14560	COG2271	Major facilitator Superfamily
HR116_RS14565	COG4948	Mandelate Racemase Muconate Lactonizing
HR116_RS14575	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS14580	COG2995	paraquat-inducible protein a
HR116_RS14585	COG3008	intermembrane lipid transfer
HR116_RS14615	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS14625	COG3162	membrane
HR116_RS14630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HR116_RS14640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HR116_RS14645	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS14650	COG0531	amino acid
HR116_RS14665	COG2072	flavoprotein involved in K transport
HR116_RS14680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS14700	COG2409	Drug exporters of the RND superfamily
HR116_RS14705	COG4447	cellulose binding
HR116_RS14715	COG2508	Transcriptional regulator
HR116_RS14800	COG4644	lycopene metabolic process
HR116_RS14880	COG2258	MOSC domain
HR116_RS14940	COG0728	peptidoglycan biosynthetic process
HR116_RS15000	COG0252	asparaginase activity
HR116_RS15030	COG1609	Transcriptional regulator
HR116_RS15040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HR116_RS15080	COG2329	Antibiotic biosynthesis monooxygenase
HR116_RS15090	COG1309	transcriptional regulator
HR116_RS15115	COG1064	alcohol dehydrogenase
HR116_RS15120	COG2207	Transcriptional regulator
HR116_RS15125	COG0640	Transcriptional regulator
HR116_RS15135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HR116_RS15140	COG0431	NADPH-dependent FMN reductase
HR116_RS15185	COG4772	TonB-dependent receptor
HR116_RS15215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS15230	COG1053	succinate dehydrogenase
HR116_RS15235	COG2188	Transcriptional regulator
HR116_RS15240	COG3469	chitinase activity
HR116_RS15250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HR116_RS15250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HR116_RS15275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS15280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HR116_RS15290	COG2175	clavaminate synthase activity
HR116_RS15300	COG1396	sequence-specific DNA binding
HR116_RS15320	COG0583	DNA-binding transcription factor activity
HR116_RS15325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS15335	COG1609	Transcriptional regulator
HR116_RS15340	COG3265	gluconokinase activity
HR116_RS15355	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS15375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS15380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS15385	COG1116	anion transmembrane transporter activity
HR116_RS15400	COG4977	sequence-specific DNA binding
HR116_RS15400	COG1917	Cupin 2, conserved barrel domain protein
HR116_RS15415	COG4771	TonB-dependent receptor
HR116_RS15435	COG1175	transmembrane transport
HR116_RS15450	COG0246	Mannitol dehydrogenase
HR116_RS15455	COG1070	Carbohydrate kinase
HR116_RS15460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HR116_RS15485	COG1464	Belongs to the NlpA lipoprotein family
HR116_RS15495	COG2011	ABC-type metal ion transport system permease component
HR116_RS15500	COG0584	glycerophosphoryl diester phosphodiesterase
HR116_RS15505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HR116_RS15510	COG3829	transcription factor binding
HR116_RS15535	COG3829	transcription factor binding
HR116_RS15610	COG3501	Rhs element vgr protein
HR116_RS15625	COG4566	intracellular signal transduction
HR116_RS15655	COG1304	FMN binding
HR116_RS15665	COG0735	belongs to the Fur family
HR116_RS15690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS15735	COG4774	siderophore transport
HR116_RS15780	COG1121	(ABC) transporter
HR116_RS15785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HR116_RS15825	COG0583	DNA-binding transcription factor activity
HR116_RS15835	COG1335	isochorismatase
HR116_RS15840	COG1335	isochorismatase
HR116_RS15930	COG1566	PFAM secretion protein HlyD family protein
HR116_RS15945	COG0583	DNA-binding transcription factor activity
HR116_RS15960	COG2217	Heavy metal translocating P-type atpase
HR116_RS15995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HR116_RS16000	COG1760	l-serine dehydratase
HR116_RS16020	COG0583	DNA-binding transcription factor activity
HR116_RS16040	COG2382	esterase
HR116_RS16050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HR116_RS16110	COG3712	iron ion homeostasis
HR116_RS16115	COG1595	DNA-templated transcription, initiation
HR116_RS16120	COG0583	DNA-binding transcription factor activity
HR116_RS16140	COG0625	glutathione transferase activity
HR116_RS16175	COG0642	Histidine kinase
HR116_RS16180	COG3258	Cytochrome c
HR116_RS16185	COG2863	cytochrome
HR116_RS16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HR116_RS16250	COG2318	DinB family
HR116_RS16265	COG0590	tRNA wobble adenosine to inosine editing
HR116_RS16270	COG2807	transmembrane transport
HR116_RS16305	COG3485	protocatechuate 3,4-dioxygenase
HR116_RS16315	COG4948	Mandelate Racemase Muconate Lactonizing
HR116_RS16330	COG4638	Rieske (2fe-2S)
HR116_RS16335	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HR116_RS16340	COG0543	2 iron, 2 sulfur cluster binding
HR116_RS16340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HR116_RS16400	COG1538	Outer membrane efflux protein
HR116_RS16405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS16410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS16430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HR116_RS16440	COG1115	amino acid carrier protein
HR116_RS16450	COG0667	Aldo Keto reductase
HR116_RS16455	COG4589	Belongs to the CDS family
HR116_RS16470	COG0671	phosphoesterase, PA-phosphatase related
HR116_RS16470	COG2453	phosphatase
HR116_RS16475	COG2267	carboxylic ester hydrolase activity
HR116_RS16480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HR116_RS16490	COG0729	surface antigen
HR116_RS16540	COG1960	acyl-CoA dehydrogenase activity
HR116_RS16545	COG0183	Belongs to the thiolase family
HR116_RS16555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HR116_RS16565	COG0318	PFAM AMP-dependent synthetase and ligase
HR116_RS16605	COG0659	secondary active sulfate transmembrane transporter activity
HR116_RS16615	COG4251	negative regulation of phosphorylation
HR116_RS16615	COG5001	Diguanylate cyclase
HR116_RS16615	COG2203	Gaf domain
HR116_RS16615	COG3706	GGDEF domain
HR116_RS16685	COG3077	Addiction module antitoxin, RelB DinJ family
HR116_RS16690	COG2003	Belongs to the UPF0758 family
HR116_RS16705	COG1475	DNA binding
HR116_RS16720	COG5489	Protein of unknown function (DUF736)
HR116_RS16725	COG1396	sequence-specific DNA binding
HR116_RS16750	COG1192	Involved in chromosome partitioning
HR116_RS16765	COG4959	Type IV secretory pathway protease TraF
HR116_RS16790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS16795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS16810	COG2207	Transcriptional regulator
HR116_RS16815	COG0583	DNA-binding transcription factor activity
HR116_RS16835	COG4962	Type ii secretion system protein e
HR116_RS16840	COG3838	Conjugal transfer protein Trbc
HR116_RS16850	COG3451	type IV secretory pathway VirB4
HR116_RS16865	COG3846	protein secretion by the type IV secretion system
HR116_RS16880	COG2948	multi-organism process
HR116_RS16900	COG4191	Histidine kinase
HR116_RS16930	COG1522	sequence-specific DNA binding
HR116_RS16945	COG2249	NAD(P)H dehydrogenase (quinone) activity
HR116_RS16965	COG0784	Response regulator, receiver
HR116_RS16965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS16965	COG2198	Histidine kinase
HR116_RS16965	COG2205	protein histidine kinase activity
HR116_RS17015	COG0629	single-stranded DNA binding
HR116_RS17095	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HR116_RS17315	COG2003	Belongs to the UPF0758 family
HR116_RS17365	COG0640	Transcriptional regulator
HR116_RS17395	COG0798	PFAM Bile acid sodium symporter
HR116_RS17405	COG0431	NADPH-dependent FMN reductase
HR116_RS17410	COG1595	DNA-templated transcription, initiation
HR116_RS17420	COG3039	Transposase
HR116_RS17455	COG3220	belongs to the UPF0276 family
HR116_RS17485	COG0785	Cytochrome C biogenesis protein
HR116_RS17490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HR116_RS17495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HR116_RS17500	COG0659	secondary active sulfate transmembrane transporter activity
HR116_RS17505	COG0589	response to stress
HR116_RS17510	COG0583	DNA-binding transcription factor activity
HR116_RS17515	COG1396	sequence-specific DNA binding
HR116_RS17525	COG0582	viral genome integration into host DNA
HR116_RS17565	COG4771	TonB-dependent receptor
HR116_RS17570	COG2197	response regulator
HR116_RS17595	COG0842	Transport permease protein
HR116_RS17600	COG0842	Transport permease protein
HR116_RS17605	COG1131	(ABC) transporter
HR116_RS17615	COG1309	transcriptional regulator
HR116_RS17625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HR116_RS17630	COG1960	acyl-CoA dehydrogenase activity
HR116_RS17660	COG0583	DNA-binding transcription factor activity
HR116_RS17675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS17685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS17690	COG1960	acyl-CoA dehydrogenase activity
HR116_RS17700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS17705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HR116_RS17710	COG0583	DNA-binding transcription factor activity
HR116_RS17750	COG2920	part of a sulfur-relay system
HR116_RS17755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HR116_RS17760	COG0435	Glutathione S-transferase
HR116_RS17775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HR116_RS17790	COG0492	ferredoxin-NADP+ reductase activity
HR116_RS17805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HR116_RS17810	COG0542	response to heat
HR116_RS17820	COG1278	Cold shock
HR116_RS17860	COG2850	peptidyl-arginine hydroxylation
HR116_RS17865	COG2153	protein acetylation
HR116_RS17960	COG2226	methyltransferase
HR116_RS17980	COG2056	Na+-H+ antiporter family
HR116_RS17985	COG0840	transmembrane signaling receptor activity
HR116_RS18000	COG0745	RESPONSE REGULATOR receiver
HR116_RS18045	COG3604	Transcriptional regulator
HR116_RS18050	COG0720	synthase
HR116_RS18090	COG2165	general secretion pathway protein
HR116_RS18100	COG1459	type II secretion system
HR116_RS18105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HR116_RS18115	COG4106	trans-aconitate 2-methyltransferase activity
HR116_RS18125	COG0583	DNA-binding transcription factor activity
HR116_RS18145	COG3209	COG3209 Rhs family protein
HR116_RS18150	COG3501	Rhs element vgr protein
HR116_RS18170	COG2819	hydrolase of the alpha beta superfamily
HR116_RS18185	COG1959	2 iron, 2 sulfur cluster binding
HR116_RS18190	COG1607	acyl-coa hydrolase
HR116_RS18260	COG0542	response to heat
HR116_RS18275	COG1280	lysine exporter protein (LysE YggA)
HR116_RS18295	COG0243	molybdopterin cofactor binding
HR116_RS18300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HR116_RS18305	COG0446	pyridine nucleotide-disulphide oxidoreductase
HR116_RS18305	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS18315	COG0789	Transcriptional regulator
HR116_RS18350	COG2837	iron assimilation
HR116_RS18355	COG0542	response to heat
HR116_RS18365	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HR116_RS18365	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HR116_RS18475	COG0024	Methionine aminopeptidase
HR116_RS18505	COG1295	ribonuclease BN
HR116_RS18515	COG1238	metal cluster binding
HR116_RS18605	COG2837	iron assimilation
HR116_RS18615	COG1024	Enoyl-CoA hydratase
HR116_RS18615	COG1250	3-hydroxyacyl-CoA dehydrogenase
HR116_RS18625	COG1051	belongs to the nudix hydrolase family
HR116_RS18675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS18680	COG2116	formate transmembrane transporter activity
HR116_RS18720	COG3655	Transcriptional regulator
HR116_RS18775	COG1335	isochorismatase
HR116_RS18795	COG0745	RESPONSE REGULATOR receiver
HR116_RS18805	COG2853	Lipoprotein
HR116_RS18815	COG2188	Transcriptional regulator
HR116_RS18860	COG0842	Transport permease protein
HR116_RS18865	COG1131	(ABC) transporter
HR116_RS18870	COG0625	glutathione transferase activity
HR116_RS18965	COG0625	glutathione transferase activity
HR116_RS18970	COG1956	GAF domain-containing protein
HR116_RS18975	COG2255	four-way junction helicase activity
HR116_RS18980	COG2205	protein histidine kinase activity
HR116_RS18980	COG5002	protein histidine kinase activity
HR116_RS18980	COG0784	Response regulator, receiver
HR116_RS18985	COG1846	Transcriptional regulator
HR116_RS18990	COG0386	Belongs to the glutathione peroxidase family
HR116_RS19000	COG0436	Aminotransferase
HR116_RS19015	COG2866	Carboxypeptidase
HR116_RS19055	COG3384	dioxygenase
HR116_RS19065	COG1024	Enoyl-CoA hydratase
HR116_RS19075	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HR116_RS19080	COG3214	Protein conserved in bacteria
HR116_RS19090	COG0583	DNA-binding transcription factor activity
HR116_RS19100	COG0583	DNA-binding transcription factor activity
HR116_RS19105	COG1846	Transcriptional regulator
HR116_RS19110	COG1764	response to oxidative stress
HR116_RS19150	COG4181	ATPase activity
HR116_RS19155	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HR116_RS19170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HR116_RS19185	COG2259	Doxx family
HR116_RS19190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HR116_RS19195	COG0084	hydrolase, TatD family'
HR116_RS19215	COG3706	GGDEF domain
HR116_RS19240	COG0714	Associated with various cellular activities
HR116_RS19250	COG0583	DNA-binding transcription factor activity
HR116_RS19260	COG0583	DNA-binding transcription factor activity
HR116_RS19290	COG1309	transcriptional regulator
HR116_RS19305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HR116_RS19310	COG1960	acyl-CoA dehydrogenase activity
HR116_RS19315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HR116_RS19345	COG1595	DNA-templated transcription, initiation
HR116_RS19350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HR116_RS19360	COG2197	response regulator
HR116_RS19365	COG2885	chlorophyll binding
HR116_RS19365	COG3047	cAMP biosynthetic process
HR116_RS19395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HR116_RS19425	COG1120	ATPase activity
HR116_RS19435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HR116_RS19465	COG0840	transmembrane signaling receptor activity
HR116_RS19470	COG0583	DNA-binding transcription factor activity
HR116_RS19475	COG1473	amidohydrolase
HR116_RS19480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS19485	COG4215	(ABC) transporter
HR116_RS19490	COG4160	amino acid transport
HR116_RS19525	COG1309	transcriptional regulator
HR116_RS19530	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS19535	COG2814	Major facilitator Superfamily
HR116_RS19545	COG3038	cytochrome b561
HR116_RS19555	COG2233	PERMEase
HR116_RS19565	COG0183	Belongs to the thiolase family
HR116_RS19580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HR116_RS19665	COG0084	hydrolase, TatD family'
HR116_RS19685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HR116_RS19695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HR116_RS19725	COG1399	metal-binding, possibly nucleic acid-binding protein
HR116_RS19735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HR116_RS19735	COG0616	signal peptide processing
HR116_RS19740	COG0546	phosphoglycolate phosphatase activity
HR116_RS19750	COG1530	ribonuclease E activity
HR116_RS19760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HR116_RS19780	COG0848	biopolymer transport protein
HR116_RS19785	COG0811	peptide transport
HR116_RS19790	COG0658	competence protein
HR116_RS19790	COG2333	competence protein COMEC
HR116_RS19815	COG4591	ABC-type transport system involved in lipoprotein release permease component
HR116_RS19830	COG0584	glycerophosphoryl diester phosphodiesterase
HR116_RS19845	COG1477	protein flavinylation
HR116_RS19880	COG1113	amino acid transport
HR116_RS19890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HR116_RS19965	COG0589	response to stress
HR116_RS19980	COG0741	lytic transglycosylase activity
HR116_RS20000	COG1070	Carbohydrate kinase
HR116_RS20005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HR116_RS20025	COG0521	Mo-molybdopterin cofactor biosynthetic process
HR116_RS20055	COG1309	transcriptional regulator
HR116_RS20060	COG0625	glutathione transferase activity
HR116_RS20070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HR116_RS20080	COG0004	ammonium transporteR
HR116_RS20105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS20105	COG2205	protein histidine kinase activity
HR116_RS20110	COG2197	response regulator
HR116_RS20115	COG3171	Protein conserved in bacteria
HR116_RS20120	COG2027	D-alanyl-D-alanine carboxypeptidase
HR116_RS20130	COG3130	regulation of translation
HR116_RS20195	COG3846	protein secretion by the type IV secretion system
HR116_RS20210	COG3451	type IV secretory pathway VirB4
HR116_RS20220	COG3838	Conjugal transfer protein Trbc
HR116_RS20225	COG4962	Type ii secretion system protein e
HR116_RS20255	COG2076	Multidrug Resistance protein
HR116_RS20265	COG0583	DNA-binding transcription factor activity
HR116_RS20300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HR116_RS20305	COG1127	ABC transporter
HR116_RS20325	COG4959	Type IV secretory pathway protease TraF
HR116_RS20370	COG5489	Protein of unknown function (DUF736)
HR116_RS20380	COG1475	DNA binding
HR116_RS20395	COG2003	Belongs to the UPF0758 family
HR116_RS20400	COG4804	nuclease activity
HR116_RS20415	COG0297	glycogen (starch) synthase activity
HR116_RS20440	COG2342	PFAM TM1410 hypothetical-related protein
HR116_RS20455	COG0714	Associated with various cellular activities
HR116_RS20490	COG0745	RESPONSE REGULATOR receiver
HR116_RS20520	COG0308	aminopeptidase N
HR116_RS20530	COG3139	Protein of unknown function (DUF1315)
HR116_RS20540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HR116_RS20565	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS20565	COG0446	pyridine nucleotide-disulphide oxidoreductase
HR116_RS20665	COG1286	toxin biosynthetic process
HR116_RS20670	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HR116_RS20675	COG0285	dihydrofolate synthase activity
HR116_RS20715	COG2226	methyltransferase
HR116_RS20735	COG0251	oxidation-reduction process
HR116_RS20740	COG0583	DNA-binding transcription factor activity
HR116_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS20775	COG0800	Aldolase
HR116_RS20780	COG0596	Alpha beta hydrolase
HR116_RS20815	COG0583	DNA-binding transcription factor activity
HR116_RS20855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HR116_RS20865	COG0438	transferase activity, transferring glycosyl groups
HR116_RS20870	COG0438	transferase activity, transferring glycosyl groups
HR116_RS20875	COG0367	asparagine synthase
HR116_RS20895	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HR116_RS20925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HR116_RS20955	COG0402	S-adenosylhomocysteine deaminase activity
HR116_RS20970	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS20985	COG0786	glutamate:sodium symporter activity
HR116_RS20990	COG3706	GGDEF domain
HR116_RS21030	COG0676	glucose-6-phosphate 1-epimerase activity
HR116_RS21040	COG3842	ATPase activity
HR116_RS21045	COG0395	ABC-type sugar transport system, permease component
HR116_RS21050	COG1175	transmembrane transport
HR116_RS21065	COG2205	protein histidine kinase activity
HR116_RS21070	COG0745	RESPONSE REGULATOR receiver
HR116_RS21100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HR116_RS21105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HR116_RS21110	COG0009	L-threonylcarbamoyladenylate synthase
HR116_RS21115	COG0613	PHP domain protein
HR116_RS21125	COG2350	Protein conserved in bacteria
HR116_RS21135	COG0745	RESPONSE REGULATOR receiver
HR116_RS21155	COG0778	Nitroreductase
HR116_RS21160	COG0727	PFAM Uncharacterised protein family (UPF0153)
HR116_RS21165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HR116_RS21170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HR116_RS21175	COG1127	ABC transporter
HR116_RS21205	COG0438	transferase activity, transferring glycosyl groups
HR116_RS21205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HR116_RS21220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HR116_RS21245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HR116_RS21255	COG1132	(ABC) transporter
HR116_RS21285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HR116_RS21290	COG3162	membrane
HR116_RS21310	COG2853	Lipoprotein
HR116_RS21325	COG1560	Kdo2-lipid A biosynthetic process
HR116_RS21335	COG2894	cell division
HR116_RS21345	COG0564	pseudouridine synthase activity
HR116_RS21375	COG1176	ABC-type spermidine putrescine transport system, permease component I
HR116_RS21390	COG0560	Phosphoserine phosphatase
HR116_RS21395	COG0604	alcohol dehydrogenase
HR116_RS21395	COG3321	synthase
HR116_RS21455	COG0385	Bile acid
HR116_RS21460	COG2076	Multidrug Resistance protein
HR116_RS21475	COG4772	TonB-dependent receptor
HR116_RS21490	COG2205	protein histidine kinase activity
HR116_RS21490	COG0784	Response regulator, receiver
HR116_RS21495	COG1201	RNA secondary structure unwinding
HR116_RS21565	COG1595	DNA-templated transcription, initiation
HR116_RS21620	COG3501	Rhs element vgr protein
HR116_RS21625	COG0537	adenosine 5'-monophosphoramidase activity
HR116_RS21635	COG1643	Atp-dependent helicase
HR116_RS21645	COG0318	PFAM AMP-dependent synthetase and ligase
HR116_RS21650	COG0318	PFAM AMP-dependent synthetase and ligase
HR116_RS21655	COG2267	carboxylic ester hydrolase activity
HR116_RS21660	COG2030	dehydratase
HR116_RS21665	COG2814	Major facilitator Superfamily
HR116_RS21705	COG0589	response to stress
HR116_RS21720	COG2084	Dehydrogenase
HR116_RS21725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HR116_RS21735	COG3639	organic phosphonate transmembrane transporter activity
HR116_RS21765	COG0583	DNA-binding transcription factor activity
HR116_RS21810	COG4221	oxidoreductase activity
HR116_RS21815	COG2124	cytochrome p450
HR116_RS21855	COG1752	Esterase of the alpha-beta hydrolase superfamily
HR116_RS21875	COG5001	Diguanylate cyclase
HR116_RS21875	COG2203	Gaf domain
HR116_RS21875	COG3706	GGDEF domain
HR116_RS21875	COG4251	negative regulation of phosphorylation
HR116_RS21880	COG0514	ATP-dependent DNA helicase (RecQ)
HR116_RS21890	COG0745	RESPONSE REGULATOR receiver
HR116_RS21905	COG0784	Response regulator, receiver
HR116_RS21905	COG0835	chemotaxis
HR116_RS21925	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HR116_RS21950	COG0697	spore germination
HR116_RS22025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HR116_RS22035	COG3454	Phosphonate metabolism
HR116_RS22040	COG4778	phosphonate C-P lyase system protein PhnL
HR116_RS22045	COG4107	phosphonate C-P lyase system protein PhnK
HR116_RS22050	COG3627	carbon phosphorus lyase activity
HR116_RS22055	COG3626	phosphonate metabolism
HR116_RS22065	COG3624	Phosphonate C-P lyase system protein PhnG
HR116_RS22070	COG2188	Transcriptional regulator
HR116_RS22075	COG3639	organic phosphonate transmembrane transporter activity
HR116_RS22080	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HR116_RS22155	COG0583	DNA-binding transcription factor activity
HR116_RS22210	COG1629	transport
HR116_RS22250	COG0508	dehydrogenase complex catalyzes the overall conversion of
HR116_RS22295	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
HR116_RS22305	COG1024	Enoyl-CoA hydratase
HR116_RS22310	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS22330	COG1346	cytolysis
HR116_RS22335	COG1380	Effector of murein hydrolase LrgA
HR116_RS22340	COG0583	DNA-binding transcription factor activity
HR116_RS22365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HR116_RS22390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS22400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS22405	COG0431	NADPH-dependent FMN reductase
HR116_RS22415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS22420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HR116_RS22425	COG0450	alkyl hydroperoxide reductase
HR116_RS22445	COG0183	Belongs to the thiolase family
HR116_RS22475	COG0367	asparagine synthase
HR116_RS22480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HR116_RS22480	COG0189	ligase activity
HR116_RS22485	COG1363	Peptidase, m42
HR116_RS22490	COG0784	Response regulator, receiver
HR116_RS22490	COG5002	protein histidine kinase activity
HR116_RS22490	COG2205	protein histidine kinase activity
HR116_RS22510	COG0513	Belongs to the DEAD box helicase family
HR116_RS22515	COG0477	Major facilitator Superfamily
HR116_RS22520	COG0668	transmembrane transport
HR116_RS22525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HR116_RS22540	COG0791	NLP P60 protein
HR116_RS22585	COG0489	protein tyrosine kinase activity
HR116_RS22640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HR116_RS22685	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS22695	COG0028	Belongs to the TPP enzyme family
HR116_RS22705	COG1414	Transcriptional regulator
HR116_RS22725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS22740	COG2264	protein methyltransferase activity
HR116_RS22745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HR116_RS22780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS22810	COG0450	alkyl hydroperoxide reductase
HR116_RS22825	COG2223	nitrite transmembrane transporter activity
HR116_RS22830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HR116_RS22835	COG0243	molybdopterin cofactor binding
HR116_RS22855	COG3842	ATPase activity
HR116_RS22965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HR116_RS22965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HR116_RS22965	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HR116_RS22970	COG1105	Belongs to the carbohydrate kinase PfkB family
HR116_RS22980	COG1609	Transcriptional regulator
HR116_RS22985	COG0084	hydrolase, TatD family'
HR116_RS22995	COG0583	DNA-binding transcription factor activity
HR116_RS23035	COG2814	Major facilitator Superfamily
HR116_RS23075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HR116_RS23110	COG0583	DNA-binding transcription factor activity
HR116_RS23120	COG0183	Belongs to the thiolase family
HR116_RS23125	COG1250	3-hydroxyacyl-CoA dehydrogenase
HR116_RS23130	COG1024	Enoyl-CoA hydratase
HR116_RS23135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HR116_RS23140	COG1960	acyl-CoA dehydrogenase activity
HR116_RS23145	COG0583	DNA-binding transcription factor activity
HR116_RS23150	COG0477	Major facilitator Superfamily
HR116_RS23155	COG2169	Transcriptional regulator
HR116_RS23155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HR116_RS23160	COG0531	amino acid
HR116_RS23185	COG0069	glutamate synthase activity
HR116_RS23215	COG1176	ABC-type spermidine putrescine transport system, permease component I
HR116_RS23220	COG1177	transmembrane transport
HR116_RS23235	COG3530	Putative quorum-sensing-regulated virulence factor
HR116_RS23240	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HR116_RS23245	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HR116_RS23265	COG1546	Belongs to the CinA family
HR116_RS23315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HR116_RS23320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HR116_RS23325	COG0583	DNA-binding transcription factor activity
HR116_RS23330	COG2391	methyltransferase activity
HR116_RS23380	COG1115	amino acid carrier protein
HR116_RS23460	COG0024	Methionine aminopeptidase
HR116_RS23470	COG0436	Aminotransferase
HR116_RS23475	COG0025	NhaP-type Na H and K H
HR116_RS23495	COG1393	Belongs to the ArsC family
HR116_RS23515	COG2166	iron-sulfur cluster assembly
HR116_RS23560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS23585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HR116_RS23590	COG1801	Protein of unknown function DUF72
HR116_RS23600	COG1214	PFAM Peptidase M22, glycoprotease
HR116_RS23620	COG0789	Transcriptional regulator
HR116_RS23635	COG2885	chlorophyll binding
HR116_RS23650	COG1073	alpha beta
HR116_RS23650	COG3064	Membrane
HR116_RS23650	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HR116_RS23685	COG5001	Diguanylate cyclase
HR116_RS23685	COG4251	negative regulation of phosphorylation
HR116_RS23685	COG3706	GGDEF domain
HR116_RS23685	COG2203	Gaf domain
HR116_RS23720	COG0477	Major facilitator Superfamily
HR116_RS23740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HR116_RS23745	COG2197	response regulator
HR116_RS23790	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS23800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HR116_RS23815	COG2255	four-way junction helicase activity
HR116_RS23840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HR116_RS23865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HR116_RS23885	COG1607	acyl-coa hydrolase
HR116_RS23910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HR116_RS23920	COG4536	flavin adenine dinucleotide binding
HR116_RS23925	COG0477	Major facilitator Superfamily
HR116_RS23965	COG2188	Transcriptional regulator
HR116_RS23970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HR116_RS23975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HR116_RS23980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HR116_RS23980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HR116_RS24025	COG0590	tRNA wobble adenosine to inosine editing
HR116_RS24030	COG2132	Multicopper oxidase
HR116_RS24035	COG2130	NADP-dependent
HR116_RS24045	COG0738	Major facilitator superfamily
HR116_RS24105	COG0583	DNA-binding transcription factor activity
HR116_RS24110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HR116_RS24120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HR116_RS24135	COG1335	isochorismatase
HR116_RS24145	COG2847	Copper chaperone PCu(A)C
HR116_RS24155	COG0739	heme binding
HR116_RS24195	COG0667	Aldo Keto reductase
HR116_RS24210	COG0436	Aminotransferase
HR116_RS24300	COG1045	serine acetyltransferase
HR116_RS24315	COG3134	Outer membrane lipoprotein
HR116_RS24330	COG1862	Preprotein translocase
HR116_RS24365	COG1278	Cold shock
HR116_RS24370	COG2200	EAL domain
HR116_RS24380	COG0795	lipopolysaccharide-transporting ATPase activity
HR116_RS24385	COG0795	lipopolysaccharide-transporting ATPase activity
HR116_RS24445	COG4120	Belongs to the binding-protein-dependent transport system permease family
HR116_RS24450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HR116_RS24455	COG0490	domain, Protein
HR116_RS24455	COG0471	metal ion transport
HR116_RS24485	COG0583	DNA-binding transcription factor activity
HR116_RS24550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS24560	COG0318	PFAM AMP-dependent synthetase and ligase
HR116_RS24585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS24595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HR116_RS24600	COG2181	nitrate reductase activity
HR116_RS24605	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HR116_RS24610	COG1140	nitrate reductase beta subunit
HR116_RS24615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HR116_RS24620	COG2223	nitrite transmembrane transporter activity
HR116_RS24630	COG3850	Histidine kinase
HR116_RS24635	COG2197	response regulator
HR116_RS24650	COG2226	methyltransferase
HR116_RS24655	COG0300	oxidoreductase activity
HR116_RS24705	COG1566	PFAM secretion protein HlyD family protein
HR116_RS24725	COG0583	DNA-binding transcription factor activity
HR116_RS24735	COG0697	spore germination
HR116_RS24745	COG1595	DNA-templated transcription, initiation
HR116_RS24750	COG3712	iron ion homeostasis
HR116_RS24755	COG4772	TonB-dependent receptor
HR116_RS24805	COG3154	lipid carrier protein
HR116_RS24810	COG0826	peptidase U32
HR116_RS24815	COG0826	peptidase U32
HR116_RS24820	COG0303	'Molybdopterin
HR116_RS24825	COG0521	Mo-molybdopterin cofactor biosynthetic process
HR116_RS24835	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HR116_RS24845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HR116_RS24870	COG0318	PFAM AMP-dependent synthetase and ligase
HR116_RS24875	COG0183	Belongs to the thiolase family
HR116_RS24885	COG2207	Transcriptional regulator
HR116_RS24895	COG1294	oxidase, subunit
HR116_RS24900	COG1271	oxidase subunit
HR116_RS24915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HR116_RS24920	COG1297	OPT oligopeptide transporter protein
HR116_RS24925	COG2175	clavaminate synthase activity
HR116_RS24930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HR116_RS24940	COG4521	taurine ABC transporter
HR116_RS24960	COG1946	Acyl-CoA thioesterase
HR116_RS24980	COG2205	protein histidine kinase activity
HR116_RS24980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS24985	COG2199	diguanylate cyclase activity
HR116_RS24985	COG2200	EAL domain
HR116_RS24985	COG2202	Pas domain
HR116_RS24990	COG2197	response regulator
HR116_RS25000	COG0513	Belongs to the DEAD box helicase family
HR116_RS25010	COG3416	Protein conserved in bacteria
HR116_RS25065	COG0653	protein targeting
HR116_RS25080	COG1643	Atp-dependent helicase
HR116_RS25085	COG1643	Atp-dependent helicase
HR116_RS25095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HR116_RS25135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HR116_RS25145	COG1960	acyl-CoA dehydrogenase activity
HR116_RS25155	COG2205	protein histidine kinase activity
HR116_RS25155	COG0784	Response regulator, receiver
HR116_RS25155	COG2198	Histidine kinase
HR116_RS25160	COG0351	phosphomethylpyrimidine kinase
HR116_RS25190	COG1702	phosphate starvation-inducible protein PhoH
HR116_RS25200	COG4535	Mg2 and Co2 transporter CorC
HR116_RS25210	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HR116_RS25245	COG2951	lytic endotransglycosylase activity
HR116_RS25275	COG1686	Belongs to the peptidase S11 family
HR116_RS25285	COG2951	lytic endotransglycosylase activity
HR116_RS25290	COG0772	Belongs to the SEDS family
HR116_RS25295	COG0768	penicillin binding
HR116_RS25335	COG0586	Pfam SNARE associated Golgi protein
HR116_RS25345	COG1346	cytolysis
HR116_RS25365	COG0702	epimerase
HR116_RS25380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HR116_RS25385	COG3284	Transcriptional regulator
HR116_RS25390	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS25395	COG0531	amino acid
HR116_RS25400	COG4303	Ethanolamine ammonia lyase large subunit
HR116_RS25410	COG0456	acetyltransferase
HR116_RS25425	COG0586	Pfam SNARE associated Golgi protein
HR116_RS25430	COG3228	Belongs to the MtfA family
HR116_RS25440	COG0745	RESPONSE REGULATOR receiver
HR116_RS25460	COG5002	protein histidine kinase activity
HR116_RS25465	COG1131	(ABC) transporter
HR116_RS25485	COG4948	Mandelate Racemase Muconate Lactonizing
HR116_RS25495	COG0142	geranyltranstransferase activity
HR116_RS25520	COG3577	Aspartyl protease
HR116_RS25530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HR116_RS25535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HR116_RS25560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HR116_RS25560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HR116_RS25575	COG2264	protein methyltransferase activity
HR116_RS25580	COG3118	belongs to the thioredoxin family
HR116_RS25610	COG3047	cAMP biosynthetic process
HR116_RS25620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HR116_RS25640	COG0531	amino acid
HR116_RS25680	COG2197	response regulator
HR116_RS25700	COG3188	usher protein
HR116_RS25705	COG3121	Chaperone
HR116_RS25720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HR116_RS25725	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS25760	COG2271	Major facilitator Superfamily
HR116_RS25765	COG1063	alcohol dehydrogenase
HR116_RS25770	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS25790	COG0745	RESPONSE REGULATOR receiver
HR116_RS25795	COG2205	protein histidine kinase activity
HR116_RS25805	COG2259	Doxx family
HR116_RS25865	COG1611	Belongs to the LOG family
HR116_RS25905	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS25910	COG3384	dioxygenase
HR116_RS25920	COG2271	Major facilitator Superfamily
HR116_RS25925	COG3971	2-oxopent-4-enoate hydratase activity
HR116_RS25940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HR116_RS25950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HR116_RS25955	COG3278	Belongs to the heme-copper respiratory oxidase family
HR116_RS25965	COG1846	Transcriptional regulator
HR116_RS25970	COG2814	Major facilitator Superfamily
HR116_RS26000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS26025	COG3284	Transcriptional regulator
HR116_RS26035	COG3199	ATP-NAD kinase
HR116_RS26040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HR116_RS26045	COG0022	dehydrogenase e1 component
HR116_RS26055	COG1063	alcohol dehydrogenase
HR116_RS26060	COG4991	sh3 domain protein
HR116_RS26065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HR116_RS26070	COG1629	transport
HR116_RS26070	COG4774	siderophore transport
HR116_RS26080	COG1120	ATPase activity
HR116_RS26085	COG4592	Periplasmic binding protein
HR116_RS26090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HR116_RS26095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HR116_RS26100	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS26105	COG0583	DNA-binding transcription factor activity
HR116_RS26110	COG2814	Major facilitator Superfamily
HR116_RS26115	COG0583	DNA-binding transcription factor activity
HR116_RS26135	COG0154	amidase activity
HR116_RS26165	COG1959	2 iron, 2 sulfur cluster binding
HR116_RS26170	COG0492	ferredoxin-NADP+ reductase activity
HR116_RS26175	COG0693	protein deglycase activity
HR116_RS26185	COG0251	oxidation-reduction process
HR116_RS26200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HR116_RS26210	COG2226	methyltransferase
HR116_RS26255	COG2271	Major facilitator Superfamily
HR116_RS26260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HR116_RS26265	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS26285	COG0765	amino acid transport
HR116_RS26290	COG0765	amino acid transport
HR116_RS26295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HR116_RS26300	COG4566	intracellular signal transduction
HR116_RS26305	COG4191	Histidine kinase
HR116_RS26315	COG1960	acyl-CoA dehydrogenase activity
HR116_RS26320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HR116_RS26340	COG2706	6-phosphogluconolactonase activity
HR116_RS26350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS26355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HR116_RS26445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HR116_RS26445	COG3433	isochorismatase activity
HR116_RS26445	COG2226	methyltransferase
HR116_RS26450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HR116_RS26450	COG2226	methyltransferase
HR116_RS26450	COG3433	isochorismatase activity
HR116_RS26460	COG1021	2,3-dihydroxybenzoate-AMP ligase
HR116_RS26485	COG2814	Major facilitator Superfamily
HR116_RS26610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HR116_RS26775	COG0739	heme binding
HR116_RS26830	COG0537	adenosine 5'-monophosphoramidase activity
HR116_RS26845	COG1765	OsmC-like protein
HR116_RS26940	COG3179	chitinase
HR116_RS27025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HR116_RS27050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HR116_RS27060	COG1176	ABC-type spermidine putrescine transport system, permease component I
HR116_RS27070	COG3842	ATPase activity
HR116_RS27080	COG2197	response regulator
HR116_RS27095	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HR116_RS27145	COG2766	serine protein kinase
HR116_RS27155	COG2719	SpoVR family
HR116_RS27175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HR116_RS27275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HR116_RS27280	COG1917	Cupin 2, conserved barrel domain protein
HR116_RS27280	COG4977	sequence-specific DNA binding
HR116_RS27285	COG3152	Membrane
HR116_RS27290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HR116_RS27295	COG1451	nucleotide metabolic process
HR116_RS27300	COG2081	HI0933 family
HR116_RS27340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HR116_RS27345	COG3622	Belongs to the hyi family
HR116_RS27355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HR116_RS27360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HR116_RS27415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HR116_RS27425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS27445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HR116_RS27455	COG2258	MOSC domain
HR116_RS27460	COG0583	DNA-binding transcription factor activity
HR116_RS27465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HR116_RS27550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HR116_RS27550	COG1648	precorrin-2 dehydrogenase activity
HR116_RS27560	COG1960	acyl-CoA dehydrogenase activity
HR116_RS27565	COG1960	acyl-CoA dehydrogenase activity
HR116_RS27570	COG1960	acyl-CoA dehydrogenase activity
HR116_RS27590	COG2226	methyltransferase
HR116_RS27590	COG1073	alpha beta
HR116_RS27605	COG3121	Chaperone
HR116_RS27615	COG1984	allophanate hydrolase subunit 2
HR116_RS27630	COG0511	ligase activity, forming carbon-carbon bonds
HR116_RS27650	COG1040	competence protein
HR116_RS27655	COG5544	Lipoprotein
HR116_RS27660	COG3585	molybdate ion transport
HR116_RS27660	COG2005	Transcriptional regulator
HR116_RS27695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HR116_RS27715	COG1953	Uracil, thiamine, allantoin
HR116_RS27720	COG1309	transcriptional regulator
HR116_RS27730	COG0625	glutathione transferase activity
HR116_RS27735	COG1595	DNA-templated transcription, initiation
HR116_RS27740	COG3712	iron ion homeostasis
HR116_RS27745	COG4774	siderophore transport
HR116_RS27775	COG4452	Inner membrane protein CreD
HR116_RS27780	COG2205	protein histidine kinase activity
HR116_RS27785	COG0745	RESPONSE REGULATOR receiver
HR116_RS27795	COG0204	Acyl-transferase
HR116_RS27805	COG0542	response to heat
HR116_RS27810	COG0477	Major facilitator Superfamily
HR116_RS27820	COG0189	ligase activity
HR116_RS27820	COG4067	protein conserved in archaea
HR116_RS27830	COG0513	Belongs to the DEAD box helicase family
HR116_RS27835	COG1289	transmembrane transporter activity
HR116_RS27845	COG0330	HflC and HflK could
HR116_RS27855	COG0306	phosphate transporter
HR116_RS27865	COG0583	DNA-binding transcription factor activity
HR116_RS27870	COG1960	acyl-CoA dehydrogenase activity
HR116_RS27885	COG1953	Uracil, thiamine, allantoin
HR116_RS27895	COG0493	'glutamate synthase
HR116_RS27905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HR116_RS27910	COG0402	S-adenosylhomocysteine deaminase activity
HR116_RS27915	COG1309	transcriptional regulator
HR116_RS27940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HR116_RS27945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HR116_RS27955	COG0513	Belongs to the DEAD box helicase family
HR116_RS27985	COG3038	cytochrome b561
HR116_RS28000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HR116_RS28030	COG0643	Histidine kinase
HR116_RS28030	COG0784	Response regulator, receiver
HR116_RS28030	COG2198	Histidine kinase
HR116_RS28095	COG0626	cystathionine gamma-synthase activity
HR116_RS28140	COG1872	DUF167
HR116_RS28145	COG1160	GTP binding
HR116_RS28155	COG2813	Specifically methylates the guanine in position
HR116_RS28155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HR116_RS28170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HR116_RS28205	COG2363	Small membrane protein
HR116_RS28225	COG2177	Part of the ABC transporter FtsEX involved in
HR116_RS28230	COG2884	Cell division ATP-binding protein ftsE
HR116_RS28235	COG0552	protein localization to endoplasmic reticulum
HR116_RS28240	COG0612	Peptidase, M16
HR116_RS28245	COG0612	Peptidase, M16
HR116_RS28250	COG0742	ribosomal rna small subunit methyltransferase
HR116_RS28260	COG0429	hydrolase of the alpha beta-hydrolase fold
HR116_RS28285	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HR116_RS28295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HR116_RS28330	COG0693	protein deglycase activity
HR116_RS28345	COG2233	PERMEase
HR116_RS28350	COG0622	Phosphoesterase
HR116_RS28370	COG0584	glycerophosphoryl diester phosphodiesterase
HR116_RS28405	COG0730	response to heat
HR116_RS28415	COG3706	GGDEF domain
HR116_RS28445	COG0702	epimerase
HR116_RS28455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HR116_RS28475	COG2234	aminopeptidase activity
HR116_RS28480	COG3204	pilus organization
HR116_RS28485	COG3842	ATPase activity
HR116_RS28495	COG1177	transmembrane transport
HR116_RS28500	COG2182	Extracellular solute-binding protein
HR116_RS28505	COG0531	amino acid
HR116_RS28515	COG3111	PFAM Bacterial OB fold (BOF) protein
HR116_RS28525	COG0179	Fumarylacetoacetate (FAA) hydrolase
HR116_RS28530	COG0277	FAD linked oxidase domain protein
HR116_RS28535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HR116_RS28595	COG4644	lycopene metabolic process
HR116_RS28600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HR116_RS28625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HR116_RS28740	COG0583	DNA-binding transcription factor activity
HR116_RS28805	COG0402	S-adenosylhomocysteine deaminase activity
HR116_RS28855	COG0789	Transcriptional regulator
HR116_RS28880	COG0668	transmembrane transport
HR116_RS28895	COG3852	Histidine kinase
HR116_RS28910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HR116_RS28940	COG4942	peptidase
HR116_RS28945	COG0793	Belongs to the peptidase S41A family
HR116_RS28950	COG2861	carbohydrate metabolic process
HR116_RS29010	COG0579	oxidoreductase
HR116_RS29020	COG1194	a g-specific adenine glycosylase
HR116_RS29030	COG0673	inositol 2-dehydrogenase activity
HR116_RS29095	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS29140	COG1566	PFAM secretion protein HlyD family protein
HR116_RS29145	COG2814	Major facilitator Superfamily
HR116_RS29165	COG4695	Portal protein
HR116_RS29250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HR116_RS29380	COG1088	dTDP-glucose 4,6-dehydratase activity
HR116_RS29385	COG1091	dTDP-4-dehydrorhamnose reductase activity
HR116_RS29460	COG1218	3'(2'),5'-bisphosphate nucleotidase
HR116_RS29465	COG0494	nUDIX hydrolase
HR116_RS29470	COG1011	Hydrolase
HR116_RS29475	COG1652	LysM domain
HR116_RS29485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HR116_RS29505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HR116_RS29515	COG0824	Thioesterase
HR116_RS29520	COG1454	alcohol dehydrogenase
HR116_RS29525	COG1960	acyl-CoA dehydrogenase activity
HR116_RS29530	COG1024	Enoyl-CoA hydratase
HR116_RS29530	COG1250	3-hydroxyacyl-CoA dehydrogenase
HR116_RS29540	COG0778	Nitroreductase
HR116_RS29565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HR116_RS29570	COG0189	ligase activity
HR116_RS29570	COG4067	protein conserved in archaea
HR116_RS29585	COG2205	protein histidine kinase activity
HR116_RS29590	COG0745	RESPONSE REGULATOR receiver
HR116_RS29595	COG2183	response to ionizing radiation
HR116_RS29625	COG0306	phosphate transporter
HR116_RS29630	COG1392	Phosphate transport regulator
HR116_RS29635	COG3025	triphosphatase activity
HR116_RS29670	COG1178	ABC-type Fe3 transport system permease component
HR116_RS29680	COG0583	DNA-binding transcription factor activity
HR116_RS29695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HR116_RS29705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HR116_RS29710	COG0006	proline dipeptidase activity
HR116_RS29735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HR116_RS29745	COG0842	Transport permease protein
HR116_RS29750	COG0842	Transport permease protein
HR116_RS29750	COG1129	ABC transporter
HR116_RS29755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HR116_RS29770	COG2271	Major facilitator Superfamily
HR116_RS29785	COG2755	lipolytic protein G-D-S-L family
HR116_RS29785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HR116_RS29815	COG0586	Pfam SNARE associated Golgi protein
HR116_RS29820	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HR116_RS29825	COG2050	protein possibly involved in aromatic compounds catabolism
HR116_RS29835	COG0672	)-iron permease
HR116_RS29840	COG1280	lysine exporter protein (LysE YggA)
HR116_RS29845	COG0861	Integral membrane protein TerC family
HR116_RS29855	COG0488	(ABC) transporter
HR116_RS29910	COG3275	phosphorelay sensor kinase activity
HR116_RS29935	COG3501	Rhs element vgr protein
HR116_RS29950	COG0598	Magnesium transport protein CorA
HR116_RS30045	COG0598	Magnesium transport protein CorA
HR116_RS30075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HR116_RS30140	COG0432	Pfam Uncharacterised protein family UPF0047
HR116_RS30145	COG0004	ammonium transporteR
HR116_RS30150	COG0347	Belongs to the P(II) protein family
HR116_RS30185	COG3328	transposase activity
HR116_RS30190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HR116_RS30215	COG0732	type I restriction modification DNA specificity domain
HR116_RS30250	COG3012	SEC-C Motif Domain Protein
HR116_RS30315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HR116_RS30325	COG0583	DNA-binding transcription factor activity
HR116_RS30340	COG0210	DNA helicase
HR116_RS30345	COG0028	Belongs to the TPP enzyme family
HR116_RS30355	COG0427	acetyl-CoA hydrolase
HR116_RS30365	COG1917	Cupin 2, conserved barrel domain protein
HR116_RS30365	COG1396	sequence-specific DNA binding
HR116_RS30375	COG0251	oxidation-reduction process
HR116_RS30405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HR116_RS30410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HR116_RS30415	COG2814	Major facilitator Superfamily
HR116_RS30420	COG1012	belongs to the aldehyde dehydrogenase family
HR116_RS30445	COG0747	negative chemotaxis
HR116_RS30460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HR116_RS30500	COG3245	cytochrome
HR116_RS30520	COG0708	Exodeoxyribonuclease III
HR116_RS30535	COG1561	YicC-like family, N-terminal region
HR116_RS30550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HR116_RS30580	COG0583	DNA-binding transcription factor activity
HR116_RS30585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HR116_RS30620	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HR116_RS30625	COG0247	lactate metabolic process
HR116_RS30630	COG0277	FAD linked oxidase domain protein
HR116_RS30635	COG0277	FAD linked oxidase domain protein
HR116_RS30640	COG2186	Transcriptional regulator
HR116_RS30670	COG1253	flavin adenine dinucleotide binding
HR116_RS30675	COG0739	heme binding
HR116_RS30695	COG0573	inorganic phosphate transmembrane transporter activity
HR116_RS30735	COG0477	Major facilitator Superfamily
HR116_RS30740	COG1607	acyl-coa hydrolase
HR116_RS30760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HR116_RS30765	COG4175	Glycine betaine
HR116_RS30770	COG4176	ABC-type proline glycine betaine transport system permease component
HR116_RS30780	COG1760	l-serine dehydratase
HR116_RS30795	COG0583	DNA-binding transcription factor activity
HR116_RS30820	COG3246	L-lysine catabolic process to acetate
HR116_RS30875	COG1902	pentaerythritol trinitrate reductase activity
HR116_RS30875	COG0446	pyridine nucleotide-disulphide oxidoreductase
HR116_RS30880	COG2181	nitrate reductase activity
HR116_RS30880	COG0247	lactate metabolic process
HR116_RS30900	COG3655	Transcriptional regulator
HR116_RS30940	COG1017	nitric oxide dioxygenase activity
HR116_RS30940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HR116_RS31025	COG0583	DNA-binding transcription factor activity
HR116_RS31035	COG2391	methyltransferase activity
HR116_RS31060	COG5016	pyruvate
HR116_RS31060	COG0511	ligase activity, forming carbon-carbon bonds
HR116_RS31065	COG0439	Biotin carboxylase
HR116_RS31070	COG0583	DNA-binding transcription factor activity
HR116_RS31085	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HR116_RS31110	COG0210	DNA helicase
HR116_RS31120	COG0427	acetyl-CoA hydrolase
HR116_RS31135	COG0438	transferase activity, transferring glycosyl groups
HR116_RS31185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HR116_RS31190	COG2755	lipolytic protein G-D-S-L family
HR116_RS31190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HR116_RS31230	COG0679	Auxin Efflux Carrier
HR116_RS31240	COG2851	Citrate transporter
HR116_RS31245	COG0861	Integral membrane protein TerC family
HR116_RS31250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HR116_RS31255	COG1690	Belongs to the RtcB family
HR116_RS31290	COG0700	Nucleoside recognition
HR116_RS31295	COG1301	dicarboxylic acid transport
HR116_RS31315	COG5002	protein histidine kinase activity
HR116_RS31320	COG3023	N-Acetylmuramoyl-L-alanine amidase
HR116_RS31325	COG2095	MarC family integral membrane protein
HR116_RS31350	COG3245	cytochrome
HR116_RS31385	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HR116_RS31390	COG0735	belongs to the Fur family
HR116_RS31400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HR116_RS31415	COG2011	ABC-type metal ion transport system permease component
HR116_RS31445	COG0531	amino acid
HR116_RS31455	COG4191	Histidine kinase
HR116_RS31490	COG4651	solute:proton antiporter activity
HR116_RS31490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HR116_RS31495	COG1607	acyl-coa hydrolase
HR116_RS31505	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS31510	COG0174	glutamine synthetase
HR116_RS31515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HR116_RS31520	COG1028	Short-chain dehydrogenase reductase Sdr
HR116_RS31545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HR116_RS31545	COG4651	solute:proton antiporter activity
HR116_RS31550	COG0477	Major facilitator Superfamily
HR116_RS31560	COG0523	cobalamin synthesis protein
HR116_RS31605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HR116_RS31625	COG2358	TRAP transporter, solute receptor (TAXI family
HR116_RS31630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HR116_RS31650	COG1349	DNA-binding transcription factor activity
HR116_RS31710	COG1475	DNA binding
HR116_RS31715	COG1192	Involved in chromosome partitioning