locus-tag	class	description
HB747_RS00035	COG2010	Cytochrome c
HB747_RS00050	COG2818	Glycosylase
HB747_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HB747_RS00080	COG0569	domain protein
HB747_RS00100	COG1652	LysM domain
HB747_RS00105	COG0758	DNA mediated transformation
HB747_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB747_RS00155	COG3119	arylsulfatase activity
HB747_RS00160	COG0583	DNA-binding transcription factor activity
HB747_RS00195	COG3360	Dodecin
HB747_RS00275	COG3174	membrane
HB747_RS00320	COG0367	asparagine synthase
HB747_RS00340	COG0583	DNA-binding transcription factor activity
HB747_RS00390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HB747_RS00395	COG0339	signal peptide processing
HB747_RS00400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HB747_RS00415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HB747_RS00430	COG2815	serine threonine protein kinase
HB747_RS00430	COG0515	serine threonine protein kinase
HB747_RS00435	COG0631	protein serine/threonine phosphatase activity
HB747_RS00450	COG1360	Flagellar Motor Protein
HB747_RS00515	COG3501	Rhs element vgr protein
HB747_RS00535	COG3501	Rhs element vgr protein
HB747_RS00575	COG0659	secondary active sulfate transmembrane transporter activity
HB747_RS00585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HB747_RS00590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HB747_RS00595	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HB747_RS00635	COG2153	protein acetylation
HB747_RS00675	COG0583	DNA-binding transcription factor activity
HB747_RS00700	COG2824	Alkylphosphonate utilization operon protein PhnA
HB747_RS00730	COG0402	S-adenosylhomocysteine deaminase activity
HB747_RS00735	COG1129	ABC transporter
HB747_RS00815	COG0583	DNA-binding transcription factor activity
HB747_RS00820	COG3485	protocatechuate 3,4-dioxygenase
HB747_RS00825	COG3485	protocatechuate 3,4-dioxygenase
HB747_RS00830	COG1414	Transcriptional regulator
HB747_RS00845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS00850	COG0583	DNA-binding transcription factor activity
HB747_RS00880	COG2233	PERMEase
HB747_RS00885	COG1309	transcriptional regulator
HB747_RS00920	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HB747_RS00935	COG0835	chemotaxis
HB747_RS00940	COG2198	Histidine kinase
HB747_RS00940	COG0643	Histidine kinase
HB747_RS00950	COG0745	RESPONSE REGULATOR receiver
HB747_RS00960	COG0583	DNA-binding transcription factor activity
HB747_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS00975	COG1116	anion transmembrane transporter activity
HB747_RS00980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS00985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS01025	COG2175	clavaminate synthase activity
HB747_RS01100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HB747_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS01135	COG1113	amino acid transport
HB747_RS01150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB747_RS01155	COG0235	Class ii aldolase
HB747_RS01160	COG1396	sequence-specific DNA binding
HB747_RS01165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HB747_RS01170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HB747_RS01180	COG0477	Major facilitator Superfamily
HB747_RS01190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HB747_RS01195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB747_RS01200	COG0583	DNA-binding transcription factor activity
HB747_RS01220	COG0673	inositol 2-dehydrogenase activity
HB747_RS01240	COG2271	Major facilitator Superfamily
HB747_RS01250	COG1309	transcriptional regulator
HB747_RS01255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HB747_RS01265	COG0477	Major facilitator Superfamily
HB747_RS01285	COG2239	Acts as a magnesium transporter
HB747_RS01345	COG3501	Rhs element vgr protein
HB747_RS01380	COG0673	inositol 2-dehydrogenase activity
HB747_RS01390	COG1194	a g-specific adenine glycosylase
HB747_RS01400	COG0579	oxidoreductase
HB747_RS01460	COG2861	carbohydrate metabolic process
HB747_RS01465	COG0793	Belongs to the peptidase S41A family
HB747_RS01470	COG4942	peptidase
HB747_RS01500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HB747_RS01515	COG3852	Histidine kinase
HB747_RS01530	COG0668	transmembrane transport
HB747_RS01555	COG0789	Transcriptional regulator
HB747_RS01640	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB747_RS01660	COG4176	ABC-type proline glycine betaine transport system permease component
HB747_RS01665	COG4175	Glycine betaine
HB747_RS01670	COG2986	histidine ammonia-lyase
HB747_RS01685	COG3501	Rhs element vgr protein
HB747_RS01690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB747_RS01710	COG0251	oxidation-reduction process
HB747_RS01715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS01720	COG1051	belongs to the nudix hydrolase family
HB747_RS01725	COG0596	Alpha beta hydrolase
HB747_RS01750	COG0765	amino acid transport
HB747_RS01755	COG1126	abc transporter atp-binding protein
HB747_RS01765	COG0840	transmembrane signaling receptor activity
HB747_RS01875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HB747_RS01895	COG0281	malic enzyme
HB747_RS01945	COG0070	glutamate synthase
HB747_RS01945	COG0067	glutamate synthase
HB747_RS01945	COG0069	glutamate synthase activity
HB747_RS01975	COG2814	Major facilitator Superfamily
HB747_RS01980	COG0583	DNA-binding transcription factor activity
HB747_RS01985	COG1192	Involved in chromosome partitioning
HB747_RS02015	COG1196	nuclear chromosome segregation
HB747_RS02015	COG3264	Mechanosensitive ion channel
HB747_RS02025	COG1960	acyl-CoA dehydrogenase activity
HB747_RS02030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HB747_RS02065	COG0859	PFAM glycosyl transferase family 9
HB747_RS02070	COG0859	PFAM glycosyl transferase family 9
HB747_RS02075	COG0438	transferase activity, transferring glycosyl groups
HB747_RS02100	COG2192	nodulation
HB747_RS02105	COG0438	transferase activity, transferring glycosyl groups
HB747_RS02125	COG1215	transferase activity, transferring glycosyl groups
HB747_RS02150	COG1960	acyl-CoA dehydrogenase activity
HB747_RS02155	COG1960	acyl-CoA dehydrogenase activity
HB747_RS02165	COG0667	Aldo Keto reductase
HB747_RS02180	COG0583	DNA-binding transcription factor activity
HB747_RS02185	COG1519	Transferase
HB747_RS02195	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS02195	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB747_RS02225	COG0833	amino acid
HB747_RS02230	COG1024	Enoyl-CoA hydratase
HB747_RS02235	COG1960	acyl-CoA dehydrogenase activity
HB747_RS02240	COG0045	succinate-CoA ligase (ADP-forming) activity
HB747_RS02255	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB747_RS02260	COG1538	Outer membrane efflux protein
HB747_RS02275	COG0494	nUDIX hydrolase
HB747_RS02285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HB747_RS02290	COG3150	esterase
HB747_RS02305	COG3577	Aspartyl protease
HB747_RS02320	COG1988	membrane-bound metal-dependent
HB747_RS02330	COG0560	Phosphoserine phosphatase
HB747_RS02330	COG3830	Belongs to the UPF0237 family
HB747_RS02335	COG5001	Diguanylate cyclase
HB747_RS02335	COG3300	MHYT domain
HB747_RS02385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HB747_RS02385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HB747_RS02390	COG0802	atpase or kinase
HB747_RS02395	COG0860	N-Acetylmuramoyl-L-alanine amidase
HB747_RS02415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HB747_RS02420	COG0330	HflC and HflK could
HB747_RS02425	COG0330	HflC and HflK could
HB747_RS02455	COG0557	exoribonuclease II activity
HB747_RS02485	COG0305	Participates in initiation and elongation during chromosome replication
HB747_RS02495	COG5001	Diguanylate cyclase
HB747_RS02495	COG3300	MHYT domain
HB747_RS02515	COG0668	transmembrane transport
HB747_RS02555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HB747_RS02570	COG0583	DNA-binding transcription factor activity
HB747_RS02600	COG2423	ornithine cyclodeaminase activity
HB747_RS02605	COG4221	oxidoreductase activity
HB747_RS02630	COG0583	DNA-binding transcription factor activity
HB747_RS02640	COG2814	Major facilitator Superfamily
HB747_RS02660	COG1595	DNA-templated transcription, initiation
HB747_RS02665	COG3712	iron ion homeostasis
HB747_RS02725	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HB747_RS02730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HB747_RS02740	COG2193	ferroxidase activity
HB747_RS02745	COG2982	Protein involved in outer membrane biogenesis
HB747_RS02750	COG0789	Transcriptional regulator
HB747_RS02775	COG0443	Heat shock 70 kDa protein
HB747_RS02790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB747_RS02835	COG0411	ABC transporter
HB747_RS02850	COG0683	leucine binding
HB747_RS02855	COG2095	MarC family integral membrane protein
HB747_RS02940	COG0023	Translation Initiation Factor
HB747_RS02975	COG1272	protein, Hemolysin III
HB747_RS02980	COG4221	oxidoreductase activity
HB747_RS03005	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HB747_RS03030	COG1283	sodium-dependent phosphate transmembrane transporter activity
HB747_RS03040	COG0534	Mate efflux family protein
HB747_RS03050	COG0463	Glycosyl transferase, family 2
HB747_RS03075	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB747_RS03075	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS03080	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HB747_RS03090	COG0437	4 iron, 4 sulfur cluster binding
HB747_RS03095	COG2864	formate dehydrogenase
HB747_RS03125	COG0531	amino acid
HB747_RS03165	COG0509	glycine decarboxylation via glycine cleavage system
HB747_RS03195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB747_RS03225	COG1522	sequence-specific DNA binding
HB747_RS03230	COG0697	spore germination
HB747_RS03250	COG0697	spore germination
HB747_RS03300	COG1620	l-lactate permease
HB747_RS03305	COG2186	Transcriptional regulator
HB747_RS03335	COG0497	DNA recombination
HB747_RS03400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HB747_RS03435	COG0195	Participates in both transcription termination and antitermination
HB747_RS03535	COG4191	Histidine kinase
HB747_RS03550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB747_RS03570	COG2252	PERMEase
HB747_RS03580	COG2321	neutral zinc metallopeptidase
HB747_RS03590	COG0436	Aminotransferase
HB747_RS03615	COG4771	TonB-dependent receptor
HB747_RS03620	COG3720	iron ion transport
HB747_RS03625	COG4558	Periplasmic binding protein
HB747_RS03630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB747_RS03665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HB747_RS03675	COG3098	single-species biofilm formation
HB747_RS03690	COG0028	Belongs to the TPP enzyme family
HB747_RS03705	COG1183	phosphatidylcholine synthase activity
HB747_RS03875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HB747_RS04000	COG2814	Major facilitator Superfamily
HB747_RS04025	COG1021	2,3-dihydroxybenzoate-AMP ligase
HB747_RS04035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HB747_RS04035	COG2226	methyltransferase
HB747_RS04035	COG3433	isochorismatase activity
HB747_RS04130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS04145	COG2706	6-phosphogluconolactonase activity
HB747_RS04165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB747_RS04170	COG1960	acyl-CoA dehydrogenase activity
HB747_RS04180	COG4191	Histidine kinase
HB747_RS04185	COG4566	intracellular signal transduction
HB747_RS04190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS04195	COG0765	amino acid transport
HB747_RS04200	COG0765	amino acid transport
HB747_RS04220	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS04225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB747_RS04230	COG2271	Major facilitator Superfamily
HB747_RS04265	COG0028	Belongs to the TPP enzyme family
HB747_RS04275	COG2226	methyltransferase
HB747_RS04285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB747_RS04300	COG0251	oxidation-reduction process
HB747_RS04310	COG0693	protein deglycase activity
HB747_RS04315	COG0492	ferredoxin-NADP+ reductase activity
HB747_RS04320	COG1959	2 iron, 2 sulfur cluster binding
HB747_RS04350	COG0154	amidase activity
HB747_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS04360	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB747_RS04365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB747_RS04370	COG4592	Periplasmic binding protein
HB747_RS04375	COG1120	ATPase activity
HB747_RS04385	COG1629	transport
HB747_RS04385	COG4774	siderophore transport
HB747_RS04390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB747_RS04395	COG4991	sh3 domain protein
HB747_RS04400	COG1063	alcohol dehydrogenase
HB747_RS04410	COG0022	dehydrogenase e1 component
HB747_RS04415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HB747_RS04420	COG3199	ATP-NAD kinase
HB747_RS04430	COG3284	Transcriptional regulator
HB747_RS04455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS04485	COG2814	Major facilitator Superfamily
HB747_RS04490	COG1846	Transcriptional regulator
HB747_RS04500	COG3278	Belongs to the heme-copper respiratory oxidase family
HB747_RS04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB747_RS04515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB747_RS04530	COG3971	2-oxopent-4-enoate hydratase activity
HB747_RS04545	COG3384	dioxygenase
HB747_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS04590	COG1611	Belongs to the LOG family
HB747_RS04650	COG2259	Doxx family
HB747_RS04660	COG2205	protein histidine kinase activity
HB747_RS04665	COG0745	RESPONSE REGULATOR receiver
HB747_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS04690	COG1063	alcohol dehydrogenase
HB747_RS04695	COG2271	Major facilitator Superfamily
HB747_RS04730	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS04735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HB747_RS04750	COG3121	Chaperone
HB747_RS04755	COG3188	usher protein
HB747_RS04775	COG2197	response regulator
HB747_RS04815	COG0531	amino acid
HB747_RS04835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HB747_RS04845	COG3047	cAMP biosynthetic process
HB747_RS04875	COG3118	belongs to the thioredoxin family
HB747_RS04880	COG2264	protein methyltransferase activity
HB747_RS04895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB747_RS04895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HB747_RS04920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HB747_RS04925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HB747_RS04935	COG3577	Aspartyl protease
HB747_RS04960	COG0142	geranyltranstransferase activity
HB747_RS04970	COG4948	Mandelate Racemase Muconate Lactonizing
HB747_RS04990	COG1131	(ABC) transporter
HB747_RS05015	COG0745	RESPONSE REGULATOR receiver
HB747_RS05025	COG3228	Belongs to the MtfA family
HB747_RS05030	COG0586	Pfam SNARE associated Golgi protein
HB747_RS05045	COG0456	acetyltransferase
HB747_RS05055	COG4303	Ethanolamine ammonia lyase large subunit
HB747_RS05060	COG0531	amino acid
HB747_RS05065	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS05070	COG3284	Transcriptional regulator
HB747_RS05090	COG0702	epimerase
HB747_RS05110	COG1346	cytolysis
HB747_RS05120	COG0586	Pfam SNARE associated Golgi protein
HB747_RS05160	COG0768	penicillin binding
HB747_RS05165	COG0772	Belongs to the SEDS family
HB747_RS05170	COG2951	lytic endotransglycosylase activity
HB747_RS05180	COG1686	Belongs to the peptidase S11 family
HB747_RS05210	COG2951	lytic endotransglycosylase activity
HB747_RS05245	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HB747_RS05255	COG4535	Mg2 and Co2 transporter CorC
HB747_RS05265	COG1702	phosphate starvation-inducible protein PhoH
HB747_RS05295	COG0351	phosphomethylpyrimidine kinase
HB747_RS05300	COG2198	Histidine kinase
HB747_RS05300	COG0784	Response regulator, receiver
HB747_RS05300	COG2205	protein histidine kinase activity
HB747_RS05310	COG1960	acyl-CoA dehydrogenase activity
HB747_RS05320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HB747_RS05360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HB747_RS05370	COG1643	Atp-dependent helicase
HB747_RS05415	COG3416	Protein conserved in bacteria
HB747_RS05425	COG0513	Belongs to the DEAD box helicase family
HB747_RS05435	COG2197	response regulator
HB747_RS05440	COG2200	EAL domain
HB747_RS05440	COG2202	Pas domain
HB747_RS05440	COG2199	diguanylate cyclase activity
HB747_RS05445	COG2205	protein histidine kinase activity
HB747_RS05445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS05465	COG1946	Acyl-CoA thioesterase
HB747_RS05470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB747_RS05485	COG4521	taurine ABC transporter
HB747_RS05495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS05500	COG2175	clavaminate synthase activity
HB747_RS05505	COG1297	OPT oligopeptide transporter protein
HB747_RS05510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB747_RS05525	COG1271	oxidase subunit
HB747_RS05530	COG1294	oxidase, subunit
HB747_RS05550	COG0183	Belongs to the thiolase family
HB747_RS05555	COG0318	PFAM AMP-dependent synthetase and ligase
HB747_RS05580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HB747_RS05590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HB747_RS05600	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB747_RS05605	COG0303	'Molybdopterin
HB747_RS05610	COG0826	peptidase U32
HB747_RS05615	COG0826	peptidase U32
HB747_RS05620	COG3154	lipid carrier protein
HB747_RS05670	COG4772	TonB-dependent receptor
HB747_RS05675	COG3712	iron ion homeostasis
HB747_RS05680	COG1595	DNA-templated transcription, initiation
HB747_RS05690	COG0697	spore germination
HB747_RS05700	COG0583	DNA-binding transcription factor activity
HB747_RS05720	COG1566	PFAM secretion protein HlyD family protein
HB747_RS05770	COG0300	oxidoreductase activity
HB747_RS05775	COG2226	methyltransferase
HB747_RS05790	COG2197	response regulator
HB747_RS05795	COG3850	Histidine kinase
HB747_RS05805	COG2223	nitrite transmembrane transporter activity
HB747_RS05810	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HB747_RS05815	COG1140	nitrate reductase beta subunit
HB747_RS05820	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HB747_RS05825	COG2181	nitrate reductase activity
HB747_RS05830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB747_RS05865	COG0318	PFAM AMP-dependent synthetase and ligase
HB747_RS05875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS05940	COG0583	DNA-binding transcription factor activity
HB747_RS05970	COG0471	metal ion transport
HB747_RS05970	COG0490	domain, Protein
HB747_RS05975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HB747_RS05980	COG4120	Belongs to the binding-protein-dependent transport system permease family
HB747_RS06030	COG0795	lipopolysaccharide-transporting ATPase activity
HB747_RS06035	COG0795	lipopolysaccharide-transporting ATPase activity
HB747_RS06045	COG2200	EAL domain
HB747_RS06065	COG1862	Preprotein translocase
HB747_RS06080	COG3134	Outer membrane lipoprotein
HB747_RS06095	COG1045	serine acetyltransferase
HB747_RS06185	COG0436	Aminotransferase
HB747_RS06200	COG0667	Aldo Keto reductase
HB747_RS06240	COG0739	heme binding
HB747_RS06250	COG2847	Copper chaperone PCu(A)C
HB747_RS06260	COG1335	isochorismatase
HB747_RS06275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HB747_RS06285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HB747_RS06290	COG0583	DNA-binding transcription factor activity
HB747_RS06340	COG0582	viral genome integration into host DNA
HB747_RS06365	COG4691	Plasmid stability protein
HB747_RS06370	COG1487	ribonuclease activity
HB747_RS06425	COG1002	Type II restriction enzyme, methylase subunits
HB747_RS06430	COG1061	Type III restriction enzyme res subunit
HB747_RS06435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HB747_RS06450	COG2132	Multicopper oxidase
HB747_RS06455	COG0590	tRNA wobble adenosine to inosine editing
HB747_RS06500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HB747_RS06500	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HB747_RS06505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HB747_RS06510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HB747_RS06515	COG2188	Transcriptional regulator
HB747_RS06555	COG0477	Major facilitator Superfamily
HB747_RS06560	COG4536	flavin adenine dinucleotide binding
HB747_RS06595	COG1607	acyl-coa hydrolase
HB747_RS06615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HB747_RS06640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HB747_RS06680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HB747_RS06690	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS06735	COG2197	response regulator
HB747_RS06740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HB747_RS06760	COG0477	Major facilitator Superfamily
HB747_RS06795	COG5001	Diguanylate cyclase
HB747_RS06795	COG4251	negative regulation of phosphorylation
HB747_RS06795	COG3706	GGDEF domain
HB747_RS06795	COG2203	Gaf domain
HB747_RS06830	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HB747_RS06830	COG3064	Membrane
HB747_RS06830	COG1073	alpha beta
HB747_RS06845	COG2885	chlorophyll binding
HB747_RS06860	COG0789	Transcriptional regulator
HB747_RS06880	COG1214	PFAM Peptidase M22, glycoprotease
HB747_RS06890	COG1801	Protein of unknown function DUF72
HB747_RS06895	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HB747_RS06920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS06965	COG2166	iron-sulfur cluster assembly
HB747_RS06985	COG1393	Belongs to the ArsC family
HB747_RS07005	COG0025	NhaP-type Na H and K H
HB747_RS07010	COG0436	Aminotransferase
HB747_RS07020	COG0024	Methionine aminopeptidase
HB747_RS07100	COG1115	amino acid carrier protein
HB747_RS07150	COG2391	methyltransferase activity
HB747_RS07155	COG0583	DNA-binding transcription factor activity
HB747_RS07160	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HB747_RS07165	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HB747_RS07215	COG1546	Belongs to the CinA family
HB747_RS07235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB747_RS07240	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HB747_RS07245	COG3530	Putative quorum-sensing-regulated virulence factor
HB747_RS07260	COG1177	transmembrane transport
HB747_RS07265	COG1176	ABC-type spermidine putrescine transport system, permease component I
HB747_RS07295	COG0069	glutamate synthase activity
HB747_RS07325	COG2169	Transcriptional regulator
HB747_RS07325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB747_RS07330	COG0477	Major facilitator Superfamily
HB747_RS07335	COG0583	DNA-binding transcription factor activity
HB747_RS07340	COG1960	acyl-CoA dehydrogenase activity
HB747_RS07345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HB747_RS07350	COG1024	Enoyl-CoA hydratase
HB747_RS07355	COG1250	3-hydroxyacyl-CoA dehydrogenase
HB747_RS07360	COG0183	Belongs to the thiolase family
HB747_RS07370	COG0583	DNA-binding transcription factor activity
HB747_RS07405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB747_RS07440	COG2814	Major facilitator Superfamily
HB747_RS07480	COG0583	DNA-binding transcription factor activity
HB747_RS07490	COG0084	hydrolase, TatD family'
HB747_RS07495	COG1609	Transcriptional regulator
HB747_RS07505	COG1105	Belongs to the carbohydrate kinase PfkB family
HB747_RS07510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB747_RS07510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HB747_RS07510	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HB747_RS07620	COG3842	ATPase activity
HB747_RS07640	COG0243	molybdopterin cofactor binding
HB747_RS07645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HB747_RS07650	COG2223	nitrite transmembrane transporter activity
HB747_RS07665	COG0450	alkyl hydroperoxide reductase
HB747_RS07695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS07735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HB747_RS07740	COG2264	protein methyltransferase activity
HB747_RS07750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HB747_RS07805	COG0489	protein tyrosine kinase activity
HB747_RS07850	COG0791	NLP P60 protein
HB747_RS07865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HB747_RS07870	COG0668	transmembrane transport
HB747_RS07875	COG0477	Major facilitator Superfamily
HB747_RS07880	COG0513	Belongs to the DEAD box helicase family
HB747_RS07900	COG0784	Response regulator, receiver
HB747_RS07900	COG5002	protein histidine kinase activity
HB747_RS07900	COG2205	protein histidine kinase activity
HB747_RS07905	COG1363	Peptidase, m42
HB747_RS07910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HB747_RS07910	COG0189	ligase activity
HB747_RS07915	COG0367	asparagine synthase
HB747_RS07945	COG0183	Belongs to the thiolase family
HB747_RS07965	COG0450	alkyl hydroperoxide reductase
HB747_RS07970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS07975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS07985	COG0431	NADPH-dependent FMN reductase
HB747_RS07990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS08000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS08025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB747_RS08050	COG0583	DNA-binding transcription factor activity
HB747_RS08055	COG1380	Effector of murein hydrolase LrgA
HB747_RS08060	COG1346	cytolysis
HB747_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS08085	COG1024	Enoyl-CoA hydratase
HB747_RS08095	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
HB747_RS08140	COG0508	dehydrogenase complex catalyzes the overall conversion of
HB747_RS08180	COG1629	transport
HB747_RS08235	COG0583	DNA-binding transcription factor activity
HB747_RS08310	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HB747_RS08315	COG3639	organic phosphonate transmembrane transporter activity
HB747_RS08320	COG2188	Transcriptional regulator
HB747_RS08325	COG3624	Phosphonate C-P lyase system protein PhnG
HB747_RS08335	COG3626	phosphonate metabolism
HB747_RS08340	COG3627	carbon phosphorus lyase activity
HB747_RS08345	COG4107	phosphonate C-P lyase system protein PhnK
HB747_RS08350	COG4778	phosphonate C-P lyase system protein PhnL
HB747_RS08365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HB747_RS08440	COG0697	spore germination
HB747_RS08465	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HB747_RS08485	COG0784	Response regulator, receiver
HB747_RS08485	COG0835	chemotaxis
HB747_RS08510	COG0514	ATP-dependent DNA helicase (RecQ)
HB747_RS08515	COG2203	Gaf domain
HB747_RS08515	COG3706	GGDEF domain
HB747_RS08515	COG4251	negative regulation of phosphorylation
HB747_RS08515	COG5001	Diguanylate cyclase
HB747_RS08535	COG1752	Esterase of the alpha-beta hydrolase superfamily
HB747_RS08575	COG2124	cytochrome p450
HB747_RS08580	COG4221	oxidoreductase activity
HB747_RS08625	COG0583	DNA-binding transcription factor activity
HB747_RS08655	COG3639	organic phosphonate transmembrane transporter activity
HB747_RS08665	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HB747_RS08670	COG2084	Dehydrogenase
HB747_RS08685	COG0589	response to stress
HB747_RS08725	COG2814	Major facilitator Superfamily
HB747_RS08730	COG2030	dehydratase
HB747_RS08735	COG2267	carboxylic ester hydrolase activity
HB747_RS08740	COG0318	PFAM AMP-dependent synthetase and ligase
HB747_RS08745	COG0318	PFAM AMP-dependent synthetase and ligase
HB747_RS08755	COG1643	Atp-dependent helicase
HB747_RS08765	COG0537	adenosine 5'-monophosphoramidase activity
HB747_RS08770	COG3501	Rhs element vgr protein
HB747_RS08825	COG1595	DNA-templated transcription, initiation
HB747_RS08890	COG1201	RNA secondary structure unwinding
HB747_RS08895	COG2205	protein histidine kinase activity
HB747_RS08895	COG0784	Response regulator, receiver
HB747_RS08910	COG4772	TonB-dependent receptor
HB747_RS08925	COG2076	Multidrug Resistance protein
HB747_RS08930	COG0385	Bile acid
HB747_RS08980	COG2200	EAL domain
HB747_RS08990	COG0604	alcohol dehydrogenase
HB747_RS08990	COG3321	synthase
HB747_RS08995	COG0560	Phosphoserine phosphatase
HB747_RS09010	COG1176	ABC-type spermidine putrescine transport system, permease component I
HB747_RS09040	COG0564	pseudouridine synthase activity
HB747_RS09050	COG2894	cell division
HB747_RS09060	COG1560	Kdo2-lipid A biosynthetic process
HB747_RS09075	COG2853	Lipoprotein
HB747_RS09095	COG3162	membrane
HB747_RS09100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB747_RS09130	COG1132	(ABC) transporter
HB747_RS09140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HB747_RS09165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB747_RS09165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HB747_RS09180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HB747_RS09180	COG0438	transferase activity, transferring glycosyl groups
HB747_RS09210	COG1127	ABC transporter
HB747_RS09215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB747_RS09220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HB747_RS09225	COG0727	PFAM Uncharacterised protein family (UPF0153)
HB747_RS09230	COG0778	Nitroreductase
HB747_RS09250	COG0745	RESPONSE REGULATOR receiver
HB747_RS09260	COG2350	Protein conserved in bacteria
HB747_RS09270	COG0613	PHP domain protein
HB747_RS09275	COG0009	L-threonylcarbamoyladenylate synthase
HB747_RS09280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HB747_RS09285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HB747_RS09315	COG0745	RESPONSE REGULATOR receiver
HB747_RS09320	COG2205	protein histidine kinase activity
HB747_RS09335	COG1175	transmembrane transport
HB747_RS09340	COG0395	ABC-type sugar transport system, permease component
HB747_RS09345	COG3842	ATPase activity
HB747_RS09355	COG0676	glucose-6-phosphate 1-epimerase activity
HB747_RS09395	COG3706	GGDEF domain
HB747_RS09400	COG0786	glutamate:sodium symporter activity
HB747_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS09430	COG0402	S-adenosylhomocysteine deaminase activity
HB747_RS09460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HB747_RS09530	COG1215	transferase activity, transferring glycosyl groups
HB747_RS09535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HB747_RS09550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HB747_RS09590	COG0583	DNA-binding transcription factor activity
HB747_RS09625	COG0596	Alpha beta hydrolase
HB747_RS09630	COG0800	Aldolase
HB747_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS09665	COG0583	DNA-binding transcription factor activity
HB747_RS09670	COG0251	oxidation-reduction process
HB747_RS09690	COG2226	methyltransferase
HB747_RS09730	COG0285	dihydrofolate synthase activity
HB747_RS09735	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB747_RS09740	COG1286	toxin biosynthetic process
HB747_RS09840	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB747_RS09840	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS09865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HB747_RS09875	COG3139	Protein of unknown function (DUF1315)
HB747_RS09885	COG0308	aminopeptidase N
HB747_RS09915	COG0745	RESPONSE REGULATOR receiver
HB747_RS09950	COG0714	Associated with various cellular activities
HB747_RS09970	COG1335	isochorismatase
HB747_RS09980	COG2342	PFAM TM1410 hypothetical-related protein
HB747_RS10005	COG0297	glycogen (starch) synthase activity
HB747_RS10055	COG3130	regulation of translation
HB747_RS10065	COG2027	D-alanyl-D-alanine carboxypeptidase
HB747_RS10070	COG3171	Protein conserved in bacteria
HB747_RS10075	COG2197	response regulator
HB747_RS10080	COG2205	protein histidine kinase activity
HB747_RS10080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS10105	COG0004	ammonium transporteR
HB747_RS10115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB747_RS10125	COG0625	glutathione transferase activity
HB747_RS10130	COG1309	transcriptional regulator
HB747_RS10160	COG0521	Mo-molybdopterin cofactor biosynthetic process
HB747_RS10180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HB747_RS10185	COG1070	Carbohydrate kinase
HB747_RS10205	COG0741	lytic transglycosylase activity
HB747_RS10220	COG0589	response to stress
HB747_RS10295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HB747_RS10305	COG1113	amino acid transport
HB747_RS10340	COG1477	protein flavinylation
HB747_RS10355	COG0584	glycerophosphoryl diester phosphodiesterase
HB747_RS10370	COG4591	ABC-type transport system involved in lipoprotein release permease component
HB747_RS10395	COG0811	peptide transport
HB747_RS10400	COG0848	biopolymer transport protein
HB747_RS10420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HB747_RS10430	COG1530	ribonuclease E activity
HB747_RS10440	COG0546	phosphoglycolate phosphatase activity
HB747_RS10445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HB747_RS10445	COG0616	signal peptide processing
HB747_RS10455	COG1399	metal-binding, possibly nucleic acid-binding protein
HB747_RS10485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB747_RS10495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HB747_RS10515	COG0084	hydrolase, TatD family'
HB747_RS10600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HB747_RS10615	COG0183	Belongs to the thiolase family
HB747_RS10625	COG2233	PERMEase
HB747_RS10645	COG2814	Major facilitator Superfamily
HB747_RS10650	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS10655	COG1309	transcriptional regulator
HB747_RS10690	COG4160	amino acid transport
HB747_RS10695	COG4215	(ABC) transporter
HB747_RS10700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS10705	COG1473	amidohydrolase
HB747_RS10710	COG0583	DNA-binding transcription factor activity
HB747_RS10715	COG0840	transmembrane signaling receptor activity
HB747_RS10745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HB747_RS10755	COG1120	ATPase activity
HB747_RS10785	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB747_RS10815	COG2885	chlorophyll binding
HB747_RS10815	COG3047	cAMP biosynthetic process
HB747_RS10820	COG2197	response regulator
HB747_RS10830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB747_RS10835	COG1595	DNA-templated transcription, initiation
HB747_RS10865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HB747_RS10870	COG1960	acyl-CoA dehydrogenase activity
HB747_RS10875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB747_RS10920	COG0583	DNA-binding transcription factor activity
HB747_RS10930	COG0583	DNA-binding transcription factor activity
HB747_RS10940	COG0714	Associated with various cellular activities
HB747_RS10990	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HB747_RS10995	COG2259	Doxx family
HB747_RS11010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HB747_RS11025	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HB747_RS11030	COG4181	ATPase activity
HB747_RS11070	COG1764	response to oxidative stress
HB747_RS11075	COG1846	Transcriptional regulator
HB747_RS11080	COG0583	DNA-binding transcription factor activity
HB747_RS11090	COG0583	DNA-binding transcription factor activity
HB747_RS11100	COG3214	Protein conserved in bacteria
HB747_RS11105	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HB747_RS11115	COG1024	Enoyl-CoA hydratase
HB747_RS11125	COG3384	dioxygenase
HB747_RS11180	COG0436	Aminotransferase
HB747_RS11190	COG0386	Belongs to the glutathione peroxidase family
HB747_RS11195	COG1846	Transcriptional regulator
HB747_RS11200	COG2205	protein histidine kinase activity
HB747_RS11200	COG0784	Response regulator, receiver
HB747_RS11200	COG5002	protein histidine kinase activity
HB747_RS11205	COG2255	four-way junction helicase activity
HB747_RS11210	COG1956	GAF domain-containing protein
HB747_RS11215	COG0625	glutathione transferase activity
HB747_RS11310	COG0625	glutathione transferase activity
HB747_RS11315	COG1131	(ABC) transporter
HB747_RS11320	COG0842	Transport permease protein
HB747_RS11365	COG2188	Transcriptional regulator
HB747_RS11375	COG2853	Lipoprotein
HB747_RS11385	COG0745	RESPONSE REGULATOR receiver
HB747_RS11425	COG5434	Belongs to the glycosyl hydrolase 28 family
HB747_RS11455	COG3655	Transcriptional regulator
HB747_RS11495	COG2116	formate transmembrane transporter activity
HB747_RS11500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS11550	COG1051	belongs to the nudix hydrolase family
HB747_RS11560	COG1250	3-hydroxyacyl-CoA dehydrogenase
HB747_RS11560	COG1024	Enoyl-CoA hydratase
HB747_RS11570	COG2837	iron assimilation
HB747_RS11655	COG1238	metal cluster binding
HB747_RS11665	COG1295	ribonuclease BN
HB747_RS11695	COG0024	Methionine aminopeptidase
HB747_RS11810	COG2948	multi-organism process
HB747_RS11840	COG3451	type IV secretory pathway VirB4
HB747_RS11855	COG4962	Type ii secretion system protein e
HB747_RS11870	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB747_RS11900	COG1238	metal cluster binding
HB747_RS11935	COG0071	Belongs to the small heat shock protein (HSP20) family
HB747_RS11940	COG0542	response to heat
HB747_RS11950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HB747_RS11975	COG0501	Belongs to the peptidase M48B family
HB747_RS11980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB747_RS11990	COG2944	sequence-specific DNA binding
HB747_RS12000	COG0583	DNA-binding transcription factor activity
HB747_RS12005	COG2814	Major facilitator Superfamily
HB747_RS12010	COG0367	asparagine synthase
HB747_RS12025	COG0156	8-amino-7-oxononanoate synthase activity
HB747_RS12050	COG1192	Involved in chromosome partitioning
HB747_RS12105	COG2003	Belongs to the UPF0758 family
HB747_RS12140	COG0602	queuosine metabolic process
HB747_RS12170	COG1201	RNA secondary structure unwinding
HB747_RS12220	COG0542	response to heat
HB747_RS12255	COG0789	Transcriptional regulator
HB747_RS12265	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB747_RS12265	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS12270	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HB747_RS12275	COG0243	molybdopterin cofactor binding
HB747_RS12295	COG1280	lysine exporter protein (LysE YggA)
HB747_RS12310	COG0542	response to heat
HB747_RS12380	COG1607	acyl-coa hydrolase
HB747_RS12385	COG1959	2 iron, 2 sulfur cluster binding
HB747_RS12395	COG2819	hydrolase of the alpha beta superfamily
HB747_RS12415	COG3501	Rhs element vgr protein
HB747_RS12420	COG3209	COG3209 Rhs family protein
HB747_RS12440	COG0583	DNA-binding transcription factor activity
HB747_RS12450	COG4106	trans-aconitate 2-methyltransferase activity
HB747_RS12460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB747_RS12465	COG1459	type II secretion system
HB747_RS12475	COG2165	general secretion pathway protein
HB747_RS12520	COG0720	synthase
HB747_RS12525	COG3604	Transcriptional regulator
HB747_RS12570	COG0745	RESPONSE REGULATOR receiver
HB747_RS12585	COG0840	transmembrane signaling receptor activity
HB747_RS12590	COG2056	Na+-H+ antiporter family
HB747_RS12605	COG2226	methyltransferase
HB747_RS12700	COG2153	protein acetylation
HB747_RS12705	COG2850	peptidyl-arginine hydroxylation
HB747_RS12745	COG1278	Cold shock
HB747_RS12755	COG0542	response to heat
HB747_RS12760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HB747_RS12775	COG0492	ferredoxin-NADP+ reductase activity
HB747_RS12790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HB747_RS12805	COG0435	Glutathione S-transferase
HB747_RS12810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HB747_RS12815	COG2920	part of a sulfur-relay system
HB747_RS12855	COG0583	DNA-binding transcription factor activity
HB747_RS12860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB747_RS12865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS12875	COG1960	acyl-CoA dehydrogenase activity
HB747_RS12880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS12890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS12905	COG2197	response regulator
HB747_RS12910	COG4771	TonB-dependent receptor
HB747_RS12990	COG1396	sequence-specific DNA binding
HB747_RS13035	COG2132	Multicopper oxidase
HB747_RS13040	COG0745	RESPONSE REGULATOR receiver
HB747_RS13045	COG5002	protein histidine kinase activity
HB747_RS13065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HB747_RS13070	COG0789	Transcriptional regulator
HB747_RS13075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HB747_RS13080	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HB747_RS13085	COG1309	transcriptional regulator
HB747_RS13090	COG0300	oxidoreductase activity
HB747_RS13110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB747_RS13130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HB747_RS13135	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB747_RS13145	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HB747_RS13160	COG2217	Heavy metal translocating P-type atpase
HB747_RS13165	COG2326	polyphosphate kinase activity
HB747_RS13200	COG0789	Transcriptional regulator
HB747_RS13265	COG2003	Belongs to the UPF0758 family
HB747_RS13320	COG3311	Transcriptional regulator
HB747_RS13325	COG1569	PIN domain
HB747_RS13395	COG0640	Transcriptional regulator
HB747_RS13405	COG0798	PFAM Bile acid sodium symporter
HB747_RS13415	COG0431	NADPH-dependent FMN reductase
HB747_RS13500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HB747_RS13510	COG0789	Transcriptional regulator
HB747_RS13530	COG0629	single-stranded DNA binding
HB747_RS13585	COG0784	Response regulator, receiver
HB747_RS13585	COG2205	protein histidine kinase activity
HB747_RS13585	COG2198	Histidine kinase
HB747_RS13585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HB747_RS13605	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB747_RS13620	COG1522	sequence-specific DNA binding
HB747_RS13650	COG4191	Histidine kinase
HB747_RS13675	COG2203	Gaf domain
HB747_RS13675	COG3706	GGDEF domain
HB747_RS13675	COG4251	negative regulation of phosphorylation
HB747_RS13675	COG5001	Diguanylate cyclase
HB747_RS13700	COG0659	secondary active sulfate transmembrane transporter activity
HB747_RS13740	COG0318	PFAM AMP-dependent synthetase and ligase
HB747_RS13750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB747_RS13760	COG0183	Belongs to the thiolase family
HB747_RS13765	COG1960	acyl-CoA dehydrogenase activity
HB747_RS13815	COG0729	surface antigen
HB747_RS13825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HB747_RS13830	COG2267	carboxylic ester hydrolase activity
HB747_RS13835	COG2453	phosphatase
HB747_RS13835	COG0671	phosphoesterase, PA-phosphatase related
HB747_RS13850	COG4589	Belongs to the CDS family
HB747_RS13855	COG0667	Aldo Keto reductase
HB747_RS13865	COG1115	amino acid carrier protein
HB747_RS13875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HB747_RS13895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS13900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS13905	COG1538	Outer membrane efflux protein
HB747_RS13965	COG0543	2 iron, 2 sulfur cluster binding
HB747_RS13965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB747_RS13970	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HB747_RS13975	COG4638	Rieske (2fe-2S)
HB747_RS13990	COG4948	Mandelate Racemase Muconate Lactonizing
HB747_RS14000	COG3485	protocatechuate 3,4-dioxygenase
HB747_RS14035	COG2807	transmembrane transport
HB747_RS14040	COG0590	tRNA wobble adenosine to inosine editing
HB747_RS14055	COG2318	DinB family
HB747_RS14115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB747_RS14120	COG2863	cytochrome
HB747_RS14125	COG3258	Cytochrome c
HB747_RS14130	COG0642	Histidine kinase
HB747_RS14165	COG0625	glutathione transferase activity
HB747_RS14185	COG0583	DNA-binding transcription factor activity
HB747_RS14190	COG1595	DNA-templated transcription, initiation
HB747_RS14195	COG3712	iron ion homeostasis
HB747_RS14270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB747_RS14280	COG2382	esterase
HB747_RS14300	COG0583	DNA-binding transcription factor activity
HB747_RS14320	COG1760	l-serine dehydratase
HB747_RS14325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HB747_RS14360	COG2217	Heavy metal translocating P-type atpase
HB747_RS14375	COG0583	DNA-binding transcription factor activity
HB747_RS14390	COG1566	PFAM secretion protein HlyD family protein
HB747_RS14450	COG1335	isochorismatase
HB747_RS14460	COG0583	DNA-binding transcription factor activity
HB747_RS14500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB747_RS14505	COG1121	(ABC) transporter
HB747_RS14595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS14620	COG0735	belongs to the Fur family
HB747_RS14630	COG1304	FMN binding
HB747_RS14660	COG4566	intracellular signal transduction
HB747_RS14675	COG3501	Rhs element vgr protein
HB747_RS14755	COG3829	transcription factor binding
HB747_RS14780	COG3829	transcription factor binding
HB747_RS14790	COG0584	glycerophosphoryl diester phosphodiesterase
HB747_RS14795	COG2011	ABC-type metal ion transport system permease component
HB747_RS14805	COG1464	Belongs to the NlpA lipoprotein family
HB747_RS14830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB747_RS14835	COG1070	Carbohydrate kinase
HB747_RS14840	COG0246	Mannitol dehydrogenase
HB747_RS14855	COG1175	transmembrane transport
HB747_RS14890	COG1917	Cupin 2, conserved barrel domain protein
HB747_RS14890	COG4977	sequence-specific DNA binding
HB747_RS14905	COG1116	anion transmembrane transporter activity
HB747_RS14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HB747_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS14935	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS14950	COG3265	gluconokinase activity
HB747_RS14955	COG1609	Transcriptional regulator
HB747_RS14965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS14970	COG0583	DNA-binding transcription factor activity
HB747_RS14990	COG1396	sequence-specific DNA binding
HB747_RS15000	COG2175	clavaminate synthase activity
HB747_RS15010	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HB747_RS15015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS15055	COG3469	chitinase activity
HB747_RS15060	COG2188	Transcriptional regulator
HB747_RS15065	COG1053	succinate dehydrogenase
HB747_RS15080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HB747_RS15110	COG4772	TonB-dependent receptor
HB747_RS15160	COG0431	NADPH-dependent FMN reductase
HB747_RS15170	COG0640	Transcriptional regulator
HB747_RS15175	COG2207	Transcriptional regulator
HB747_RS15180	COG1064	alcohol dehydrogenase
HB747_RS15205	COG1309	transcriptional regulator
HB747_RS15215	COG2329	Antibiotic biosynthesis monooxygenase
HB747_RS15255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB747_RS15265	COG1609	Transcriptional regulator
HB747_RS15295	COG0252	asparaginase activity
HB747_RS15300	COG1115	amino acid carrier protein
HB747_RS15355	COG0728	peptidoglycan biosynthetic process
HB747_RS15415	COG2258	MOSC domain
HB747_RS15455	COG2508	Transcriptional regulator
HB747_RS15465	COG4447	cellulose binding
HB747_RS15470	COG2409	Drug exporters of the RND superfamily
HB747_RS15495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS15510	COG2072	flavoprotein involved in K transport
HB747_RS15525	COG0531	amino acid
HB747_RS15530	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS15535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HB747_RS15545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB747_RS15550	COG3162	membrane
HB747_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS15595	COG2995	paraquat-inducible protein a
HB747_RS15600	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS15610	COG4948	Mandelate Racemase Muconate Lactonizing
HB747_RS15615	COG2271	Major facilitator Superfamily
HB747_RS15630	COG3618	amidohydrolase
HB747_RS15635	COG2271	Major facilitator Superfamily
HB747_RS15675	COG0765	amino acid transport
HB747_RS15700	COG2130	NADP-dependent
HB747_RS15705	COG1309	transcriptional regulator
HB747_RS15725	COG0366	Alpha amylase catalytic
HB747_RS15730	COG0517	IMP dehydrogenase activity
HB747_RS15750	COG1063	alcohol dehydrogenase
HB747_RS15765	COG3546	catalase activity
HB747_RS15770	COG3685	Protein conserved in bacteria
HB747_RS15795	COG2890	protein-(glutamine-N5) methyltransferase activity
HB747_RS15810	COG4191	Histidine kinase
HB747_RS15810	COG0784	Response regulator, receiver
HB747_RS15840	COG1363	Peptidase, m42
HB747_RS15880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HB747_RS15920	COG3568	Endonuclease Exonuclease Phosphatase
HB747_RS15925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB747_RS15930	COG0392	lysyltransferase activity
HB747_RS15940	COG0366	Alpha amylase catalytic
HB747_RS15960	COG1285	pathogenesis
HB747_RS15980	COG0058	SHG alpha-glucan phosphorylase activity
HB747_RS15995	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS16000	COG1546	Belongs to the CinA family
HB747_RS16030	COG2323	membrane
HB747_RS16050	COG3121	Chaperone
HB747_RS16060	COG3188	usher protein
HB747_RS16065	COG3121	Chaperone
HB747_RS16075	COG3969	phosphoadenosine phosphosulfate
HB747_RS16085	COG1475	DNA binding
HB747_RS16090	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS16095	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HB747_RS16100	COG0583	DNA-binding transcription factor activity
HB747_RS16120	COG1063	alcohol dehydrogenase
HB747_RS16130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB747_RS16130	COG2169	Transcriptional regulator
HB747_RS16145	COG0583	DNA-binding transcription factor activity
HB747_RS16150	COG2814	Major facilitator Superfamily
HB747_RS16170	COG1984	allophanate hydrolase subunit 2
HB747_RS16180	COG0028	Belongs to the TPP enzyme family
HB747_RS16190	COG0300	oxidoreductase activity
HB747_RS16225	COG2814	Major facilitator Superfamily
HB747_RS16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HB747_RS16255	COG0596	Alpha beta hydrolase
HB747_RS16260	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HB747_RS16265	COG0367	asparagine synthase
HB747_RS16275	COG1522	sequence-specific DNA binding
HB747_RS16290	COG1113	amino acid transport
HB747_RS16295	COG2010	Cytochrome c
HB747_RS16300	COG2010	Cytochrome c
HB747_RS16325	COG5001	Diguanylate cyclase
HB747_RS16335	COG4206	TonB-dependent receptor
HB747_RS16340	COG2192	nodulation
HB747_RS16345	COG2814	Major facilitator Superfamily
HB747_RS16375	COG1104	cysteine desulfurase activity
HB747_RS16380	COG4172	Belongs to the ABC transporter superfamily
HB747_RS16385	COG4239	(ABC) transporter, permease
HB747_RS16390	COG4174	ABC transporter (Permease)
HB747_RS16400	COG4771	TonB-dependent receptor
HB747_RS16415	COG0583	DNA-binding transcription factor activity
HB747_RS16435	COG1595	DNA-templated transcription, initiation
HB747_RS16450	COG2207	Transcriptional regulator
HB747_RS16470	COG0564	pseudouridine synthase activity
HB747_RS16480	COG0531	amino acid
HB747_RS16485	COG0174	glutamine synthetase
HB747_RS16520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB747_RS16540	COG1522	sequence-specific DNA binding
HB747_RS16580	COG1309	transcriptional regulator
HB747_RS16585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS16590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS16600	COG3204	pilus organization
HB747_RS16605	COG0789	Transcriptional regulator
HB747_RS16610	COG1960	acyl-CoA dehydrogenase activity
HB747_RS16615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HB747_RS16645	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB747_RS16655	COG2271	Major facilitator Superfamily
HB747_RS16660	COG3290	protein histidine kinase activity
HB747_RS16660	COG3829	transcription factor binding
HB747_RS16665	COG2610	gluconate transmembrane transporter activity
HB747_RS16670	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS16675	COG2031	fatty acid transporter
HB747_RS16690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HB747_RS16695	COG0583	DNA-binding transcription factor activity
HB747_RS16700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HB747_RS16705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB747_RS16725	COG2205	protein histidine kinase activity
HB747_RS16765	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS16770	COG4993	Dehydrogenase
HB747_RS16770	COG2010	Cytochrome c
HB747_RS16790	COG3851	Histidine kinase
HB747_RS16810	COG0784	Response regulator, receiver
HB747_RS16810	COG2205	protein histidine kinase activity
HB747_RS16830	COG2194	sulfuric ester hydrolase activity
HB747_RS16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HB747_RS16850	COG1609	Transcriptional regulator
HB747_RS16855	COG1172	Belongs to the binding-protein-dependent transport system permease family
HB747_RS16860	COG1129	ABC transporter
HB747_RS16885	COG2010	Cytochrome c
HB747_RS16890	COG0753	catalase activity
HB747_RS16930	COG1944	ATP diphosphatase activity
HB747_RS16950	COG4771	TonB-dependent receptor
HB747_RS16955	COG0275	rRNA processing
HB747_RS16960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB747_RS16960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB747_RS16975	COG0579	oxidoreductase
HB747_RS17010	COG1595	DNA-templated transcription, initiation
HB747_RS17015	COG3712	iron ion homeostasis
HB747_RS17035	COG2814	Major facilitator Superfamily
HB747_RS17085	COG2197	response regulator
HB747_RS17110	COG2366	antibiotic biosynthetic process
HB747_RS17125	COG0625	glutathione transferase activity
HB747_RS17140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB747_RS17145	COG0417	DNA replication proofreading
HB747_RS17190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS17260	COG1309	transcriptional regulator
HB747_RS17280	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HB747_RS17285	COG0583	DNA-binding transcription factor activity
HB747_RS17295	COG2354	Protein conserved in bacteria
HB747_RS17300	COG3278	Belongs to the heme-copper respiratory oxidase family
HB747_RS17310	COG2239	Acts as a magnesium transporter
HB747_RS17315	COG0583	DNA-binding transcription factor activity
HB747_RS17325	COG5001	Diguanylate cyclase
HB747_RS17325	COG2203	Gaf domain
HB747_RS17325	COG3706	GGDEF domain
HB747_RS17325	COG4251	negative regulation of phosphorylation
HB747_RS17330	COG4977	sequence-specific DNA binding
HB747_RS17335	COG3813	Protein conserved in bacteria
HB747_RS17395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB747_RS17420	COG0604	alcohol dehydrogenase
HB747_RS17425	COG0616	signal peptide processing
HB747_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS17455	COG0583	DNA-binding transcription factor activity
HB747_RS17480	COG1024	Enoyl-CoA hydratase
HB747_RS17490	COG0531	amino acid
HB747_RS17495	COG1982	Orn Lys Arg decarboxylase major
HB747_RS17505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HB747_RS17525	COG0741	lytic transglycosylase activity
HB747_RS17525	COG1388	LysM domain
HB747_RS17530	COG4166	transmembrane transport
HB747_RS17535	COG4166	transmembrane transport
HB747_RS17540	COG4174	ABC transporter (Permease)
HB747_RS17545	COG4239	(ABC) transporter, permease
HB747_RS17550	COG4172	Belongs to the ABC transporter superfamily
HB747_RS17560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB747_RS17575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB747_RS17595	COG0745	RESPONSE REGULATOR receiver
HB747_RS17600	COG2205	protein histidine kinase activity
HB747_RS17605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HB747_RS17650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HB747_RS17670	COG0589	response to stress
HB747_RS17690	COG2201	protein-glutamate methylesterase activity
HB747_RS17700	COG2223	nitrite transmembrane transporter activity
HB747_RS17705	COG0515	serine threonine protein kinase
HB747_RS17710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HB747_RS17715	COG2146	nitrite reductase [NAD(P)H] activity
HB747_RS17740	COG0668	transmembrane transport
HB747_RS17775	COG0189	ligase activity
HB747_RS17775	COG4067	protein conserved in archaea
HB747_RS17815	COG2909	trisaccharide binding
HB747_RS17820	COG2909	trisaccharide binding
HB747_RS17855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HB747_RS17905	COG0519	Catalyzes the synthesis of GMP from XMP
HB747_RS17920	COG0667	Aldo Keto reductase
HB747_RS17935	COG0183	Belongs to the thiolase family
HB747_RS17955	COG1305	Transglutaminase-like
HB747_RS17965	COG2308	Evidence 4 Homologs of previously reported genes of
HB747_RS17970	COG0505	Belongs to the CarA family
HB747_RS17990	COG1317	bacterial-type flagellum organization
HB747_RS18100	COG4789	Type iii secretion
HB747_RS18150	COG4790	Type iii secretion
HB747_RS18155	COG4794	Type iii secretion
HB747_RS18160	COG4791	protein targeting
HB747_RS18165	COG4792	protein secretion
HB747_RS18245	COG2840	Smr protein MutS2
HB747_RS18265	COG2815	serine threonine protein kinase
HB747_RS18265	COG0515	serine threonine protein kinase
HB747_RS18305	COG2204	response regulator
HB747_RS18350	COG0625	glutathione transferase activity
HB747_RS18355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HB747_RS18370	COG3135	benzoate transporter
HB747_RS18385	COG2130	NADP-dependent
HB747_RS18395	COG0840	transmembrane signaling receptor activity
HB747_RS18405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB747_RS18445	COG0745	RESPONSE REGULATOR receiver
HB747_RS18450	COG2205	protein histidine kinase activity
HB747_RS18475	COG1960	acyl-CoA dehydrogenase activity
HB747_RS18485	COG1024	Enoyl-CoA hydratase
HB747_RS18490	COG1250	3-hydroxyacyl-CoA dehydrogenase
HB747_RS18495	COG2186	Transcriptional regulator
HB747_RS18505	COG0628	permease
HB747_RS18515	COG0625	glutathione transferase activity
HB747_RS18545	COG1022	Amp-dependent synthetase and ligase
HB747_RS18575	COG0784	Response regulator, receiver
HB747_RS18575	COG2205	protein histidine kinase activity
HB747_RS18575	COG5002	protein histidine kinase activity
HB747_RS18615	COG1846	Transcriptional regulator
HB747_RS18625	COG2010	Cytochrome c
HB747_RS18625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HB747_RS18630	COG2010	Cytochrome c
HB747_RS18630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HB747_RS18635	COG2207	Transcriptional regulator
HB747_RS18710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HB747_RS18715	COG1053	succinate dehydrogenase
HB747_RS18720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HB747_RS18725	COG2009	succinate dehydrogenase
HB747_RS18755	COG2084	Dehydrogenase
HB747_RS18770	COG3738	Protein conserved in bacteria
HB747_RS18795	COG0251	oxidation-reduction process
HB747_RS18800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS18810	COG0174	glutamine synthetase
HB747_RS18815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS18835	COG0840	transmembrane signaling receptor activity
HB747_RS18850	COG3278	Belongs to the heme-copper respiratory oxidase family
HB747_RS18865	COG2010	Cytochrome c
HB747_RS18870	COG3278	Belongs to the heme-copper respiratory oxidase family
HB747_RS18885	COG2010	Cytochrome c
HB747_RS18890	COG0348	domain, Protein
HB747_RS18900	COG2217	Heavy metal translocating P-type atpase
HB747_RS18940	COG2076	Multidrug Resistance protein
HB747_RS18970	COG1960	acyl-CoA dehydrogenase activity
HB747_RS18985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HB747_RS19015	COG1196	nuclear chromosome segregation
HB747_RS19045	COG0402	S-adenosylhomocysteine deaminase activity
HB747_RS19055	COG2252	PERMEase
HB747_RS19095	COG3501	Rhs element vgr protein
HB747_RS19115	COG2233	PERMEase
HB747_RS19130	COG1309	transcriptional regulator
HB747_RS19140	COG3960	tartronate-semialdehyde synthase activity
HB747_RS19145	COG3622	Belongs to the hyi family
HB747_RS19150	COG2084	Dehydrogenase
HB747_RS19160	COG0469	pyruvate kinase activity
HB747_RS19165	COG4413	Urea transporter
HB747_RS19170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB747_RS19185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HB747_RS19195	COG3192	ethanolamine utilization protein
HB747_RS19210	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB747_RS19215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HB747_RS19290	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HB747_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS19330	COG0835	chemotaxis
HB747_RS19340	COG1192	Involved in chromosome partitioning
HB747_RS19345	COG1360	Flagellar Motor Protein
HB747_RS19350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HB747_RS19360	COG2198	Histidine kinase
HB747_RS19360	COG0784	Response regulator, receiver
HB747_RS19360	COG0643	Histidine kinase
HB747_RS19390	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HB747_RS19395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HB747_RS19415	COG1987	bacterial-type flagellum assembly
HB747_RS19455	COG2832	Protein of unknown function (DUF454)
HB747_RS19470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS19475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS19485	COG5001	Diguanylate cyclase
HB747_RS19485	COG3300	MHYT domain
HB747_RS19570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB747_RS19590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB747_RS19600	COG3264	Mechanosensitive ion channel
HB747_RS19600	COG1196	nuclear chromosome segregation
HB747_RS19605	COG0116	Belongs to the methyltransferase superfamily
HB747_RS19605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HB747_RS19615	COG0210	DNA helicase
HB747_RS19640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HB747_RS19675	COG2207	Transcriptional regulator
HB747_RS19680	COG4221	oxidoreductase activity
HB747_RS19700	COG1247	-acetyltransferase
HB747_RS19720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HB747_RS19760	COG5006	permease, DMT superfamily
HB747_RS19775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HB747_RS19790	COG3795	YCII-related domain
HB747_RS19805	COG4941	Belongs to the sigma-70 factor family
HB747_RS19815	COG3795	YCII-related domain
HB747_RS19825	COG2197	response regulator
HB747_RS19830	COG1982	Orn Lys Arg decarboxylase major
HB747_RS19835	COG0189	ligase activity
HB747_RS19840	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS19855	COG0765	amino acid transport
HB747_RS19860	COG0765	amino acid transport
HB747_RS19865	COG1126	abc transporter atp-binding protein
HB747_RS19890	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS19905	COG1253	flavin adenine dinucleotide binding
HB747_RS19910	COG0300	oxidoreductase activity
HB747_RS19920	COG0583	DNA-binding transcription factor activity
HB747_RS19925	COG3591	Belongs to the peptidase S1B family
HB747_RS19925	COG1864	DNA RNA non-specific endonuclease
HB747_RS19930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HB747_RS19935	COG4319	ketosteroid isomerase
HB747_RS19950	COG4774	siderophore transport
HB747_RS19995	COG2814	Major facilitator Superfamily
HB747_RS20015	COG0583	DNA-binding transcription factor activity
HB747_RS20025	COG0121	glutamine amidotransferase
HB747_RS20055	COG3712	iron ion homeostasis
HB747_RS20060	COG1595	DNA-templated transcription, initiation
HB747_RS20075	COG1230	cation diffusion facilitator family transporter
HB747_RS20080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB747_RS20140	COG1960	acyl-CoA dehydrogenase activity
HB747_RS20160	COG0406	alpha-ribazole phosphatase activity
HB747_RS20190	COG0778	Nitroreductase
HB747_RS20205	COG4206	TonB-dependent receptor
HB747_RS20215	COG1802	Transcriptional regulator
HB747_RS20225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS20225	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HB747_RS20260	COG0477	Major facilitator Superfamily
HB747_RS20280	COG0765	amino acid transport
HB747_RS20290	COG1126	abc transporter atp-binding protein
HB747_RS20300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HB747_RS20305	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS20355	COG4191	Histidine kinase
HB747_RS20355	COG0784	Response regulator, receiver
HB747_RS20410	COG1289	transmembrane transporter activity
HB747_RS20425	COG2207	Transcriptional regulator
HB747_RS20445	COG2249	NAD(P)H dehydrogenase (quinone) activity
HB747_RS20450	COG2957	Belongs to the agmatine deiminase family
HB747_RS20465	COG2957	Belongs to the agmatine deiminase family
HB747_RS20470	COG0583	DNA-binding transcription factor activity
HB747_RS20485	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HB747_RS20510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HB747_RS20520	COG0318	PFAM AMP-dependent synthetase and ligase
HB747_RS20525	COG0367	asparagine synthase
HB747_RS20535	COG2211	Major facilitator Superfamily
HB747_RS20585	COG1335	isochorismatase
HB747_RS20590	COG0583	DNA-binding transcription factor activity
HB747_RS20600	COG0791	NLP P60 protein
HB747_RS20605	COG0791	NLP P60 protein
HB747_RS20615	COG3829	transcription factor binding
HB747_RS20630	COG2818	Glycosylase
HB747_RS20655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HB747_RS20660	COG1960	acyl-CoA dehydrogenase activity
HB747_RS20670	COG0625	glutathione transferase activity
HB747_RS20690	COG3447	MASE1 domain protein
HB747_RS20690	COG5002	protein histidine kinase activity
HB747_RS20690	COG5001	Diguanylate cyclase
HB747_RS20700	COG0745	RESPONSE REGULATOR receiver
HB747_RS20710	COG4459	periplasmic nitrate reductase
HB747_RS20715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB747_RS20715	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB747_RS20720	COG3062	negative regulation of establishment of protein localization
HB747_RS20730	COG3043	anaerobic respiration
HB747_RS20735	COG3005	denitrification pathway
HB747_RS20740	COG2951	lytic endotransglycosylase activity
HB747_RS20745	COG0861	Integral membrane protein TerC family
HB747_RS20770	COG2977	Belongs to the P-Pant transferase superfamily
HB747_RS20775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HB747_RS20790	COG2226	methyltransferase
HB747_RS20805	COG2205	protein histidine kinase activity
HB747_RS20810	COG0745	RESPONSE REGULATOR receiver
HB747_RS20815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB747_RS20815	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HB747_RS20820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HB747_RS20825	COG1943	Transposase
HB747_RS20860	COG0531	amino acid
HB747_RS20890	COG0583	DNA-binding transcription factor activity
HB747_RS20895	COG3257	ureidoglycine aminohydrolase activity
HB747_RS20910	COG3321	synthase
HB747_RS20910	COG0604	alcohol dehydrogenase
HB747_RS20910	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS20915	COG2197	response regulator
HB747_RS20955	COG0583	DNA-binding transcription factor activity
HB747_RS20960	COG0667	Aldo Keto reductase
HB747_RS20985	COG0242	peptide deformylase activity
HB747_RS20995	COG2199	diguanylate cyclase activity
HB747_RS21000	COG2885	chlorophyll binding
HB747_RS21030	COG1132	(ABC) transporter
HB747_RS21040	COG4628	conserved protein (DUF2132)
HB747_RS21045	COG2133	pyrroloquinoline quinone binding
HB747_RS21060	COG2207	Transcriptional regulator
HB747_RS21065	COG0477	Major facilitator Superfamily
HB747_RS21080	COG2882	bacterial-type flagellum organization
HB747_RS21115	COG4191	Histidine kinase
HB747_RS21135	COG1516	flagellar protein fliS
HB747_RS21140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HB747_RS21150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HB747_RS21155	COG1216	Glycosyl transferase, family 2
HB747_RS21155	COG0438	transferase activity, transferring glycosyl groups
HB747_RS21180	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS21185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HB747_RS21205	COG1256	bacterial-type flagellum assembly
HB747_RS21230	COG4787	bacterial-type flagellum-dependent cell motility
HB747_RS21240	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HB747_RS21250	COG1815	bacterial-type flagellum-dependent cell motility
HB747_RS21295	COG0326	Molecular chaperone. Has ATPase activity
HB747_RS21310	COG3189	MarR family transcriptional regulator
HB747_RS21330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HB747_RS21345	COG2212	antiporter activity
HB747_RS21355	COG0651	ATP synthesis coupled electron transport
HB747_RS21360	COG1006	Multisubunit Na H antiporter MnhC subunit
HB747_RS21365	COG2111	Na H antiporter
HB747_RS21365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HB747_RS21370	COG3133	Outer membrane lipoprotein
HB747_RS21380	COG1929	Belongs to the glycerate kinase type-1 family
HB747_RS21385	COG2610	gluconate transmembrane transporter activity
HB747_RS21390	COG3835	regulator
HB747_RS21400	COG2885	chlorophyll binding
HB747_RS21415	COG1199	ATP-dependent helicase activity
HB747_RS21455	COG2860	membrane
HB747_RS21470	COG0653	protein targeting
HB747_RS21475	COG0625	glutathione transferase activity
HB747_RS21500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS21505	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS21530	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS21535	COG1960	acyl-CoA dehydrogenase activity
HB747_RS21540	COG1024	Enoyl-CoA hydratase
HB747_RS21545	COG1960	acyl-CoA dehydrogenase activity
HB747_RS21555	COG2814	Major facilitator Superfamily
HB747_RS21560	COG2030	dehydratase
HB747_RS21570	COG0183	Belongs to the thiolase family
HB747_RS21600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HB747_RS21605	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HB747_RS21620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HB747_RS21630	COG0425	Belongs to the sulfur carrier protein TusA family
HB747_RS21685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HB747_RS21690	COG3188	usher protein
HB747_RS21715	COG1051	belongs to the nudix hydrolase family
HB747_RS21740	COG0602	queuosine metabolic process
HB747_RS21745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HB747_RS21775	COG0824	Thioesterase
HB747_RS21805	COG0783	Belongs to the Dps family
HB747_RS21850	COG3118	belongs to the thioredoxin family
HB747_RS21885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HB747_RS21900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HB747_RS21940	COG3122	Protein conserved in bacteria
HB747_RS21950	COG3956	TIGRFAM MazG family protein
HB747_RS21955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB747_RS21985	COG2205	protein histidine kinase activity
HB747_RS21985	COG0784	Response regulator, receiver
HB747_RS21985	COG5002	protein histidine kinase activity
HB747_RS21990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB747_RS22040	COG3038	cytochrome b561
HB747_RS22055	COG4807	Protein conserved in bacteria
HB747_RS22065	COG2239	Acts as a magnesium transporter
HB747_RS22135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HB747_RS22230	COG2301	Belongs to the HpcH HpaI aldolase family
HB747_RS22240	COG2079	MmgE PrpD family protein
HB747_RS22250	COG1960	acyl-CoA dehydrogenase activity
HB747_RS22255	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HB747_RS22260	COG0583	DNA-binding transcription factor activity
HB747_RS22265	COG0583	DNA-binding transcription factor activity
HB747_RS22315	COG1113	amino acid transport
HB747_RS22335	COG0604	alcohol dehydrogenase
HB747_RS22335	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS22335	COG3321	synthase
HB747_RS22345	COG5001	Diguanylate cyclase
HB747_RS22345	COG5002	protein histidine kinase activity
HB747_RS22365	COG0271	Belongs to the BolA IbaG family
HB747_RS22405	COG0492	ferredoxin-NADP+ reductase activity
HB747_RS22410	COG0450	alkyl hydroperoxide reductase
HB747_RS22415	COG3447	MASE1 domain protein
HB747_RS22415	COG5001	Diguanylate cyclase
HB747_RS22415	COG5002	protein histidine kinase activity
HB747_RS22445	COG1307	EDD domain protein, DegV family
HB747_RS22455	COG1309	transcriptional regulator
HB747_RS22460	COG0386	Belongs to the glutathione peroxidase family
HB747_RS22485	COG0204	Acyl-transferase
HB747_RS22490	COG2885	chlorophyll binding
HB747_RS22495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HB747_RS22510	COG2267	carboxylic ester hydrolase activity
HB747_RS22560	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HB747_RS22610	COG0546	phosphoglycolate phosphatase activity
HB747_RS22625	COG3023	N-Acetylmuramoyl-L-alanine amidase
HB747_RS22640	COG0656	L-ascorbic acid biosynthetic process
HB747_RS22665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HB747_RS22675	COG1802	Transcriptional regulator
HB747_RS22685	COG0372	Belongs to the citrate synthase family
HB747_RS22695	COG2828	Protein conserved in bacteria
HB747_RS22700	COG2079	MmgE PrpD family protein
HB747_RS22715	COG1113	amino acid transport
HB747_RS22745	COG0583	DNA-binding transcription factor activity
HB747_RS22750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HB747_RS22760	COG4206	TonB-dependent receptor
HB747_RS22770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HB747_RS22835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB747_RS22915	COG3180	Ammonia monooxygenase
HB747_RS22925	COG2720	vancomycin resistance protein
HB747_RS22940	COG1960	acyl-CoA dehydrogenase activity
HB747_RS22945	COG1024	Enoyl-CoA hydratase
HB747_RS22965	COG2910	NAD(P)H-binding
HB747_RS22970	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HB747_RS23070	COG0583	DNA-binding transcription factor activity
HB747_RS23085	COG0463	Glycosyl transferase, family 2
HB747_RS23095	COG0154	amidase activity
HB747_RS23115	COG0583	DNA-binding transcription factor activity
HB747_RS23125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HB747_RS23160	COG2831	hemolysin activation secretion protein
HB747_RS23300	COG0420	3'-5' exonuclease activity
HB747_RS23310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HB747_RS23315	COG1074	ATP-dependent DNA helicase activity
HB747_RS23320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HB747_RS23325	COG0095	Lipoate-protein ligase
HB747_RS23330	COG0697	spore germination
HB747_RS23345	COG0840	transmembrane signaling receptor activity
HB747_RS23355	COG0306	phosphate transporter
HB747_RS23415	COG4964	Belongs to the GSP D family
HB747_RS23455	COG0788	formyltetrahydrofolate deformylase activity
HB747_RS23465	COG2925	Exonuclease
HB747_RS23495	COG0714	Associated with various cellular activities
HB747_RS23525	COG0589	response to stress
HB747_RS23535	COG1024	Enoyl-CoA hydratase
HB747_RS23545	COG3706	GGDEF domain
HB747_RS23565	COG0693	protein deglycase activity
HB747_RS23580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB747_RS23595	COG0154	amidase activity
HB747_RS23605	COG1473	amidohydrolase
HB747_RS23620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HB747_RS23625	COG0426	domain, Protein
HB747_RS23625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HB747_RS23645	COG0589	response to stress
HB747_RS23660	COG2814	Major facilitator Superfamily
HB747_RS23665	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS23680	COG1918	ferrous iron import across plasma membrane
HB747_RS23695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HB747_RS23735	COG1704	LemA family
HB747_RS23760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS23765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS23780	COG3642	lipopolysaccharide core region biosynthetic process
HB747_RS23790	COG2205	protein histidine kinase activity
HB747_RS23795	COG0745	RESPONSE REGULATOR receiver
HB747_RS23830	COG3030	protein affecting phage T7 exclusion by the F plasmid
HB747_RS23840	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS23865	COG0668	transmembrane transport
HB747_RS23875	COG0745	RESPONSE REGULATOR receiver
HB747_RS23890	COG2096	Adenosyltransferase
HB747_RS23895	COG0494	nUDIX hydrolase
HB747_RS23915	COG0739	heme binding
HB747_RS23915	COG0741	lytic transglycosylase activity
HB747_RS23915	COG1196	nuclear chromosome segregation
HB747_RS23960	COG0772	Belongs to the SEDS family
HB747_RS23975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HB747_RS24030	COG2823	Periplasmic or secreted lipoprotein
HB747_RS24035	COG2969	positive regulation of protein catabolic process
HB747_RS24040	COG0625	glutathione transferase activity
HB747_RS24045	COG2857	Cytochrome c1
HB747_RS24050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HB747_RS24055	COG0723	plastoquinol--plastocyanin reductase activity
HB747_RS24070	COG0667	Aldo Keto reductase
HB747_RS24075	COG1960	acyl-CoA dehydrogenase activity
HB747_RS24090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB747_RS24100	COG2945	thiolester hydrolase activity
HB747_RS24120	COG2951	lytic endotransglycosylase activity
HB747_RS24130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HB747_RS24170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HB747_RS24175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HB747_RS24180	COG1127	ABC transporter
HB747_RS24190	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HB747_RS24205	COG1137	ATPase activity
HB747_RS24260	COG0312	modulator of DNA gyrase
HB747_RS24270	COG0312	modulator of DNA gyrase
HB747_RS24275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HB747_RS24285	COG1530	ribonuclease E activity
HB747_RS24300	COG1792	Involved in formation and maintenance of cell shape
HB747_RS24305	COG1077	Cell shape determining protein MreB Mrl
HB747_RS24325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HB747_RS24330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB747_RS24335	COG4676	Protein conserved in bacteria
HB747_RS24340	COG5445	Predicted secreted protein (DUF2300)
HB747_RS24355	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HB747_RS24360	COG4676	Protein conserved in bacteria
HB747_RS24365	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HB747_RS24380	COG0747	negative chemotaxis
HB747_RS24385	COG0747	negative chemotaxis
HB747_RS24400	COG0747	negative chemotaxis
HB747_RS24410	COG0747	negative chemotaxis
HB747_RS24415	COG0601	transmembrane transport
HB747_RS24420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HB747_RS24425	COG0444	Belongs to the ABC transporter superfamily
HB747_RS24430	COG4608	Belongs to the ABC transporter superfamily
HB747_RS24445	COG1984	allophanate hydrolase subunit 2
HB747_RS24465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HB747_RS24470	COG4774	siderophore transport
HB747_RS24485	COG2194	sulfuric ester hydrolase activity
HB747_RS24495	COG0019	diaminopimelate decarboxylase activity
HB747_RS24535	COG4969	Belongs to the N-Me-Phe pilin family
HB747_RS24600	COG1252	NADH dehydrogenase
HB747_RS24605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HB747_RS24610	COG2831	hemolysin activation secretion protein
HB747_RS24625	COG1192	Involved in chromosome partitioning
HB747_RS24650	COG0305	Participates in initiation and elongation during chromosome replication
HB747_RS24740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HB747_RS24755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HB747_RS24780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HB747_RS24950	COG2135	peptidase activity
HB747_RS25130	COG3609	addiction module antidote protein, CC2985 family
HB747_RS25240	COG4969	Belongs to the N-Me-Phe pilin family
HB747_RS25280	COG1047	Peptidyl-prolyl cis-trans
HB747_RS25295	COG0196	riboflavin kinase activity
HB747_RS25310	COG3045	CreA protein
HB747_RS25335	COG0142	geranyltranstransferase activity
HB747_RS25350	COG0545	Peptidyl-prolyl cis-trans isomerase
HB747_RS25370	COG1067	ATP-dependent peptidase activity
HB747_RS25395	COG4650	regulator
HB747_RS25410	COG1690	Belongs to the RtcB family
HB747_RS25415	COG3541	Predicted nucleotidyltransferase
HB747_RS25435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HB747_RS25460	COG1136	(ABC) transporter
HB747_RS25460	COG0577	efflux transmembrane transporter activity
HB747_RS25470	COG0488	(ABC) transporter
HB747_RS25490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HB747_RS25495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS25520	COG0523	cobalamin synthesis protein
HB747_RS25525	COG2879	small protein
HB747_RS25530	COG1966	Carbon starvation protein
HB747_RS25600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HB747_RS25600	COG3608	succinylglutamate desuccinylase aspartoacylase
HB747_RS25605	COG2010	Cytochrome c
HB747_RS25640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HB747_RS25650	COG0833	amino acid
HB747_RS25655	COG2119	membrane
HB747_RS25670	COG0501	Belongs to the peptidase M48B family
HB747_RS25675	COG0840	transmembrane signaling receptor activity
HB747_RS25680	COG2135	peptidase activity
HB747_RS25685	COG1285	pathogenesis
HB747_RS25800	COG1090	epimerase
HB747_RS25805	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HB747_RS25815	COG0789	Transcriptional regulator
HB747_RS25835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HB747_RS25890	COG0012	GTP binding
HB747_RS25905	COG3549	Plasmid maintenance system killer
HB747_RS25915	COG0288	reversible hydration of carbon dioxide
HB747_RS25925	COG0456	acetyltransferase
HB747_RS25970	COG1840	ABC-type Fe3 transport system, periplasmic component
HB747_RS25975	COG1178	ABC-type Fe3 transport system permease component
HB747_RS25980	COG3008	intermembrane lipid transfer
HB747_RS25985	COG2995	paraquat-inducible protein a
HB747_RS25990	COG2995	paraquat-inducible protein a
HB747_RS26025	COG0739	heme binding
HB747_RS26080	COG0537	adenosine 5'-monophosphoramidase activity
HB747_RS26095	COG1765	OsmC-like protein
HB747_RS26215	COG3179	chitinase
HB747_RS26230	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HB747_RS26255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HB747_RS26265	COG1176	ABC-type spermidine putrescine transport system, permease component I
HB747_RS26275	COG3842	ATPase activity
HB747_RS26285	COG2197	response regulator
HB747_RS26300	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HB747_RS26315	COG3344	reverse transcriptase
HB747_RS26355	COG2766	serine protein kinase
HB747_RS26365	COG2719	SpoVR family
HB747_RS26385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HB747_RS26425	COG3344	reverse transcriptase
HB747_RS26495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB747_RS26500	COG1917	Cupin 2, conserved barrel domain protein
HB747_RS26500	COG4977	sequence-specific DNA binding
HB747_RS26505	COG3152	Membrane
HB747_RS26510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HB747_RS26515	COG1451	nucleotide metabolic process
HB747_RS26520	COG2081	HI0933 family
HB747_RS26560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HB747_RS26565	COG3622	Belongs to the hyi family
HB747_RS26575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HB747_RS26580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB747_RS26635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HB747_RS26645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HB747_RS26665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HB747_RS26675	COG2258	MOSC domain
HB747_RS26680	COG0583	DNA-binding transcription factor activity
HB747_RS26685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HB747_RS26770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HB747_RS26770	COG1648	precorrin-2 dehydrogenase activity
HB747_RS26780	COG1960	acyl-CoA dehydrogenase activity
HB747_RS26785	COG1960	acyl-CoA dehydrogenase activity
HB747_RS26790	COG1960	acyl-CoA dehydrogenase activity
HB747_RS26810	COG2226	methyltransferase
HB747_RS26810	COG1073	alpha beta
HB747_RS26825	COG3121	Chaperone
HB747_RS26840	COG1984	allophanate hydrolase subunit 2
HB747_RS26855	COG0511	ligase activity, forming carbon-carbon bonds
HB747_RS26875	COG1040	competence protein
HB747_RS26880	COG5544	Lipoprotein
HB747_RS26885	COG3585	molybdate ion transport
HB747_RS26885	COG2005	Transcriptional regulator
HB747_RS26920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HB747_RS26940	COG1953	Uracil, thiamine, allantoin
HB747_RS26945	COG1309	transcriptional regulator
HB747_RS26955	COG0625	glutathione transferase activity
HB747_RS26960	COG1595	DNA-templated transcription, initiation
HB747_RS26965	COG3712	iron ion homeostasis
HB747_RS26970	COG4774	siderophore transport
HB747_RS27000	COG4452	Inner membrane protein CreD
HB747_RS27005	COG2205	protein histidine kinase activity
HB747_RS27010	COG0745	RESPONSE REGULATOR receiver
HB747_RS27020	COG0204	Acyl-transferase
HB747_RS27030	COG0542	response to heat
HB747_RS27035	COG0477	Major facilitator Superfamily
HB747_RS27045	COG0189	ligase activity
HB747_RS27045	COG4067	protein conserved in archaea
HB747_RS27055	COG0513	Belongs to the DEAD box helicase family
HB747_RS27060	COG1289	transmembrane transporter activity
HB747_RS27070	COG0330	HflC and HflK could
HB747_RS27080	COG0306	phosphate transporter
HB747_RS27090	COG0583	DNA-binding transcription factor activity
HB747_RS27095	COG1960	acyl-CoA dehydrogenase activity
HB747_RS27110	COG1953	Uracil, thiamine, allantoin
HB747_RS27120	COG0493	'glutamate synthase
HB747_RS27130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HB747_RS27135	COG0402	S-adenosylhomocysteine deaminase activity
HB747_RS27140	COG1309	transcriptional regulator
HB747_RS27165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB747_RS27170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HB747_RS27180	COG0513	Belongs to the DEAD box helicase family
HB747_RS27210	COG3038	cytochrome b561
HB747_RS27225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HB747_RS27255	COG2198	Histidine kinase
HB747_RS27255	COG0784	Response regulator, receiver
HB747_RS27255	COG0643	Histidine kinase
HB747_RS27320	COG0626	cystathionine gamma-synthase activity
HB747_RS27365	COG1872	DUF167
HB747_RS27370	COG1160	GTP binding
HB747_RS27380	COG2813	Specifically methylates the guanine in position
HB747_RS27380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HB747_RS27395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HB747_RS27430	COG2363	Small membrane protein
HB747_RS27450	COG2177	Part of the ABC transporter FtsEX involved in
HB747_RS27455	COG2884	Cell division ATP-binding protein ftsE
HB747_RS27460	COG0552	protein localization to endoplasmic reticulum
HB747_RS27465	COG0612	Peptidase, M16
HB747_RS27470	COG0612	Peptidase, M16
HB747_RS27475	COG0742	ribosomal rna small subunit methyltransferase
HB747_RS27485	COG0429	hydrolase of the alpha beta-hydrolase fold
HB747_RS27510	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HB747_RS27520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HB747_RS27555	COG0693	protein deglycase activity
HB747_RS27570	COG2233	PERMEase
HB747_RS27575	COG0622	Phosphoesterase
HB747_RS27595	COG0584	glycerophosphoryl diester phosphodiesterase
HB747_RS27630	COG0730	response to heat
HB747_RS27640	COG3706	GGDEF domain
HB747_RS27670	COG0702	epimerase
HB747_RS27680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HB747_RS27695	COG2234	aminopeptidase activity
HB747_RS27700	COG3204	pilus organization
HB747_RS27705	COG3842	ATPase activity
HB747_RS27715	COG1177	transmembrane transport
HB747_RS27720	COG2182	Extracellular solute-binding protein
HB747_RS27725	COG0531	amino acid
HB747_RS27735	COG3111	PFAM Bacterial OB fold (BOF) protein
HB747_RS27745	COG0179	Fumarylacetoacetate (FAA) hydrolase
HB747_RS27750	COG0277	FAD linked oxidase domain protein
HB747_RS27755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HB747_RS27820	COG1177	transmembrane transport
HB747_RS27825	COG1176	ABC-type spermidine putrescine transport system, permease component I
HB747_RS27830	COG3842	ATPase activity
HB747_RS27850	COG0174	glutamine synthetase
HB747_RS27855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HB747_RS27860	COG0174	glutamine synthetase
HB747_RS27865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HB747_RS27890	COG3706	GGDEF domain
HB747_RS27925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HB747_RS27935	COG4208	sulfate ABC transporter
HB747_RS27955	COG0501	Belongs to the peptidase M48B family
HB747_RS27975	COG2807	transmembrane transport
HB747_RS27980	COG0583	DNA-binding transcription factor activity
HB747_RS27995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HB747_RS28005	COG0745	RESPONSE REGULATOR receiver
HB747_RS28085	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS28120	COG1846	Transcriptional regulator
HB747_RS28130	COG1566	PFAM secretion protein HlyD family protein
HB747_RS28155	COG4695	Portal protein
HB747_RS28380	COG3654	unkown
HB747_RS28385	COG1088	dTDP-glucose 4,6-dehydratase activity
HB747_RS28390	COG1091	dTDP-4-dehydrorhamnose reductase activity
HB747_RS28455	COG1218	3'(2'),5'-bisphosphate nucleotidase
HB747_RS28460	COG0494	nUDIX hydrolase
HB747_RS28465	COG1011	Hydrolase
HB747_RS28470	COG1652	LysM domain
HB747_RS28480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HB747_RS28500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HB747_RS28510	COG0824	Thioesterase
HB747_RS28515	COG1454	alcohol dehydrogenase
HB747_RS28520	COG1960	acyl-CoA dehydrogenase activity
HB747_RS28525	COG1250	3-hydroxyacyl-CoA dehydrogenase
HB747_RS28525	COG1024	Enoyl-CoA hydratase
HB747_RS28535	COG0778	Nitroreductase
HB747_RS28560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HB747_RS28565	COG4067	protein conserved in archaea
HB747_RS28565	COG0189	ligase activity
HB747_RS28580	COG2205	protein histidine kinase activity
HB747_RS28585	COG0745	RESPONSE REGULATOR receiver
HB747_RS28590	COG2183	response to ionizing radiation
HB747_RS28620	COG0306	phosphate transporter
HB747_RS28625	COG1392	Phosphate transport regulator
HB747_RS28630	COG3025	triphosphatase activity
HB747_RS28665	COG1178	ABC-type Fe3 transport system permease component
HB747_RS28675	COG0583	DNA-binding transcription factor activity
HB747_RS28690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB747_RS28700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HB747_RS28705	COG0006	proline dipeptidase activity
HB747_RS28730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HB747_RS28740	COG0842	Transport permease protein
HB747_RS28745	COG0842	Transport permease protein
HB747_RS28745	COG1129	ABC transporter
HB747_RS28750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HB747_RS28765	COG2271	Major facilitator Superfamily
HB747_RS28810	COG0586	Pfam SNARE associated Golgi protein
HB747_RS28815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HB747_RS28820	COG2050	protein possibly involved in aromatic compounds catabolism
HB747_RS28830	COG0672	)-iron permease
HB747_RS28835	COG1280	lysine exporter protein (LysE YggA)
HB747_RS28840	COG0861	Integral membrane protein TerC family
HB747_RS28850	COG0488	(ABC) transporter
HB747_RS28905	COG3275	phosphorelay sensor kinase activity
HB747_RS28935	COG3501	Rhs element vgr protein
HB747_RS28945	COG0598	Magnesium transport protein CorA
HB747_RS28975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HB747_RS29040	COG0432	Pfam Uncharacterised protein family UPF0047
HB747_RS29045	COG0004	ammonium transporteR
HB747_RS29050	COG0347	Belongs to the P(II) protein family
HB747_RS29060	COG0606	chelatase, subunit chli
HB747_RS29065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB747_RS29075	COG0583	DNA-binding transcription factor activity
HB747_RS29090	COG0210	DNA helicase
HB747_RS29095	COG0028	Belongs to the TPP enzyme family
HB747_RS29105	COG0427	acetyl-CoA hydrolase
HB747_RS29115	COG1396	sequence-specific DNA binding
HB747_RS29115	COG1917	Cupin 2, conserved barrel domain protein
HB747_RS29125	COG0251	oxidation-reduction process
HB747_RS29160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HB747_RS29165	COG2814	Major facilitator Superfamily
HB747_RS29170	COG1012	belongs to the aldehyde dehydrogenase family
HB747_RS29195	COG0747	negative chemotaxis
HB747_RS29210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HB747_RS29250	COG3245	cytochrome
HB747_RS29270	COG0708	Exodeoxyribonuclease III
HB747_RS29285	COG1561	YicC-like family, N-terminal region
HB747_RS29300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HB747_RS29330	COG0583	DNA-binding transcription factor activity
HB747_RS29335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HB747_RS29370	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HB747_RS29375	COG0247	lactate metabolic process
HB747_RS29380	COG0277	FAD linked oxidase domain protein
HB747_RS29385	COG0277	FAD linked oxidase domain protein
HB747_RS29390	COG2186	Transcriptional regulator
HB747_RS29420	COG1253	flavin adenine dinucleotide binding
HB747_RS29425	COG0739	heme binding
HB747_RS29445	COG0573	inorganic phosphate transmembrane transporter activity
HB747_RS29485	COG0477	Major facilitator Superfamily
HB747_RS29490	COG1607	acyl-coa hydrolase
HB747_RS29510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HB747_RS29515	COG4175	Glycine betaine
HB747_RS29520	COG4176	ABC-type proline glycine betaine transport system permease component
HB747_RS29530	COG1760	l-serine dehydratase
HB747_RS29545	COG0583	DNA-binding transcription factor activity
HB747_RS29570	COG3246	L-lysine catabolic process to acetate
HB747_RS29625	COG1902	pentaerythritol trinitrate reductase activity
HB747_RS29625	COG0446	pyridine nucleotide-disulphide oxidoreductase
HB747_RS29630	COG2181	nitrate reductase activity
HB747_RS29630	COG0247	lactate metabolic process
HB747_RS29650	COG3655	Transcriptional regulator
HB747_RS29690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HB747_RS29690	COG1017	nitric oxide dioxygenase activity
HB747_RS29775	COG0583	DNA-binding transcription factor activity
HB747_RS29785	COG2391	methyltransferase activity
HB747_RS29810	COG0511	ligase activity, forming carbon-carbon bonds
HB747_RS29810	COG5016	pyruvate
HB747_RS29815	COG0439	Biotin carboxylase
HB747_RS29820	COG0583	DNA-binding transcription factor activity
HB747_RS29835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HB747_RS29860	COG0210	DNA helicase
HB747_RS29870	COG0427	acetyl-CoA hydrolase
HB747_RS29885	COG0438	transferase activity, transferring glycosyl groups
HB747_RS29930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HB747_RS29935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HB747_RS29935	COG2755	lipolytic protein G-D-S-L family
HB747_RS29975	COG0679	Auxin Efflux Carrier
HB747_RS29985	COG2851	Citrate transporter
HB747_RS29990	COG0861	Integral membrane protein TerC family
HB747_RS29995	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HB747_RS30000	COG1690	Belongs to the RtcB family
HB747_RS30035	COG0700	Nucleoside recognition
HB747_RS30040	COG1301	dicarboxylic acid transport
HB747_RS30060	COG5002	protein histidine kinase activity
HB747_RS30065	COG3023	N-Acetylmuramoyl-L-alanine amidase
HB747_RS30070	COG2095	MarC family integral membrane protein
HB747_RS30095	COG3245	cytochrome
HB747_RS30130	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HB747_RS30135	COG0735	belongs to the Fur family
HB747_RS30145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HB747_RS30160	COG2011	ABC-type metal ion transport system permease component
HB747_RS30190	COG0531	amino acid
HB747_RS30200	COG4191	Histidine kinase
HB747_RS30230	COG4651	solute:proton antiporter activity
HB747_RS30230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB747_RS30235	COG1607	acyl-coa hydrolase
HB747_RS30245	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS30250	COG0174	glutamine synthetase
HB747_RS30255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HB747_RS30260	COG1028	Short-chain dehydrogenase reductase Sdr
HB747_RS30285	COG4651	solute:proton antiporter activity
HB747_RS30285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HB747_RS30290	COG0477	Major facilitator Superfamily
HB747_RS30300	COG0523	cobalamin synthesis protein
HB747_RS30345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HB747_RS30365	COG2358	TRAP transporter, solute receptor (TAXI family
HB747_RS30390	COG1349	DNA-binding transcription factor activity
HB747_RS30450	COG1475	DNA binding
HB747_RS30455	COG1192	Involved in chromosome partitioning