locus-tag	class	description
HW10_RS00065	COG1566	PFAM secretion protein HlyD family protein
HW10_RS00080	COG0583	DNA-binding transcription factor activity
HW10_RS00095	COG2217	Heavy metal translocating P-type atpase
HW10_RS00130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HW10_RS00135	COG1760	l-serine dehydratase
HW10_RS00155	COG0583	DNA-binding transcription factor activity
HW10_RS00175	COG2382	esterase
HW10_RS00185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS00230	COG3712	iron ion homeostasis
HW10_RS00235	COG1595	DNA-templated transcription, initiation
HW10_RS00240	COG0583	DNA-binding transcription factor activity
HW10_RS00260	COG0625	glutathione transferase activity
HW10_RS00295	COG0642	Histidine kinase
HW10_RS00300	COG3258	Cytochrome c
HW10_RS00305	COG2863	cytochrome
HW10_RS00310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS00370	COG2318	DinB family
HW10_RS00385	COG0590	tRNA wobble adenosine to inosine editing
HW10_RS00390	COG2807	transmembrane transport
HW10_RS00425	COG3485	protocatechuate 3,4-dioxygenase
HW10_RS00435	COG4948	Mandelate Racemase Muconate Lactonizing
HW10_RS00450	COG4638	Rieske (2fe-2S)
HW10_RS00455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HW10_RS00460	COG0543	2 iron, 2 sulfur cluster binding
HW10_RS00460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HW10_RS00520	COG1538	Outer membrane efflux protein
HW10_RS00525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS00530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS00550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HW10_RS00560	COG1115	amino acid carrier protein
HW10_RS00570	COG0667	Aldo Keto reductase
HW10_RS00575	COG4589	Belongs to the CDS family
HW10_RS00590	COG2453	phosphatase
HW10_RS00590	COG0671	phosphoesterase, PA-phosphatase related
HW10_RS00595	COG2267	carboxylic ester hydrolase activity
HW10_RS00600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HW10_RS00610	COG0729	surface antigen
HW10_RS00660	COG1960	acyl-CoA dehydrogenase activity
HW10_RS00665	COG0183	Belongs to the thiolase family
HW10_RS00675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HW10_RS00685	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS00720	COG0659	secondary active sulfate transmembrane transporter activity
HW10_RS00730	COG5001	Diguanylate cyclase
HW10_RS00730	COG3706	GGDEF domain
HW10_RS00730	COG4251	negative regulation of phosphorylation
HW10_RS00730	COG2203	Gaf domain
HW10_RS00755	COG4191	Histidine kinase
HW10_RS00785	COG1522	sequence-specific DNA binding
HW10_RS00800	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW10_RS00820	COG2205	protein histidine kinase activity
HW10_RS00820	COG0784	Response regulator, receiver
HW10_RS00820	COG2198	Histidine kinase
HW10_RS00820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS00860	COG4771	TonB-dependent receptor
HW10_RS00865	COG2197	response regulator
HW10_RS00880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS00890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS00895	COG1960	acyl-CoA dehydrogenase activity
HW10_RS00905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS00910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS00915	COG0583	DNA-binding transcription factor activity
HW10_RS00985	COG2920	part of a sulfur-relay system
HW10_RS00990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HW10_RS00995	COG0435	Glutathione S-transferase
HW10_RS01010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HW10_RS01025	COG0492	ferredoxin-NADP+ reductase activity
HW10_RS01040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HW10_RS01045	COG0542	response to heat
HW10_RS01055	COG1278	Cold shock
HW10_RS01095	COG2850	peptidyl-arginine hydroxylation
HW10_RS01100	COG2153	protein acetylation
HW10_RS01195	COG2226	methyltransferase
HW10_RS01215	COG2056	Na+-H+ antiporter family
HW10_RS01220	COG0840	transmembrane signaling receptor activity
HW10_RS01275	COG3604	Transcriptional regulator
HW10_RS01280	COG0720	synthase
HW10_RS01320	COG2165	general secretion pathway protein
HW10_RS01330	COG1459	type II secretion system
HW10_RS01335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW10_RS01355	COG0583	DNA-binding transcription factor activity
HW10_RS01400	COG2819	hydrolase of the alpha beta superfamily
HW10_RS01410	COG1959	2 iron, 2 sulfur cluster binding
HW10_RS01415	COG1607	acyl-coa hydrolase
HW10_RS01485	COG0542	response to heat
HW10_RS01500	COG1280	lysine exporter protein (LysE YggA)
HW10_RS01520	COG0243	molybdopterin cofactor binding
HW10_RS01525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HW10_RS01530	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS01530	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS01540	COG0789	Transcriptional regulator
HW10_RS01575	COG0542	response to heat
HW10_RS01585	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HW10_RS01585	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HW10_RS01620	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HW10_RS01625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS01650	COG1401	restriction endodeoxyribonuclease activity
HW10_RS01650	COG1401	restriction endodeoxyribonuclease activity
HW10_RS01655	COG0732	type I restriction modification DNA specificity domain
HW10_RS01660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HW10_RS01675	COG3012	SEC-C Motif Domain Protein
HW10_RS01765	COG0024	Methionine aminopeptidase
HW10_RS01795	COG1295	ribonuclease BN
HW10_RS01805	COG1238	metal cluster binding
HW10_RS01890	COG2837	iron assimilation
HW10_RS01900	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS01900	COG1024	Enoyl-CoA hydratase
HW10_RS01910	COG1051	belongs to the nudix hydrolase family
HW10_RS01965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS01970	COG2116	formate transmembrane transporter activity
HW10_RS02010	COG3655	Transcriptional regulator
HW10_RS02040	COG5434	Belongs to the glycosyl hydrolase 28 family
HW10_RS02070	COG1335	isochorismatase
HW10_RS02085	COG3179	chitinase
HW10_RS02315	COG0745	RESPONSE REGULATOR receiver
HW10_RS02325	COG2853	Lipoprotein
HW10_RS02335	COG2188	Transcriptional regulator
HW10_RS02380	COG0842	Transport permease protein
HW10_RS02385	COG1131	(ABC) transporter
HW10_RS02390	COG0625	glutathione transferase activity
HW10_RS02415	COG2200	EAL domain
HW10_RS02440	COG0625	glutathione transferase activity
HW10_RS02445	COG1956	GAF domain-containing protein
HW10_RS02450	COG2255	four-way junction helicase activity
HW10_RS02455	COG0784	Response regulator, receiver
HW10_RS02455	COG5002	protein histidine kinase activity
HW10_RS02455	COG2205	protein histidine kinase activity
HW10_RS02460	COG1846	Transcriptional regulator
HW10_RS02465	COG0386	Belongs to the glutathione peroxidase family
HW10_RS02475	COG0436	Aminotransferase
HW10_RS02490	COG2866	Carboxypeptidase
HW10_RS02530	COG3384	dioxygenase
HW10_RS02540	COG1024	Enoyl-CoA hydratase
HW10_RS02550	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HW10_RS02555	COG3214	Protein conserved in bacteria
HW10_RS02565	COG0583	DNA-binding transcription factor activity
HW10_RS02575	COG0583	DNA-binding transcription factor activity
HW10_RS02580	COG1846	Transcriptional regulator
HW10_RS02585	COG1764	response to oxidative stress
HW10_RS02625	COG4181	ATPase activity
HW10_RS02630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HW10_RS02645	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HW10_RS02660	COG2259	Doxx family
HW10_RS02665	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HW10_RS02670	COG0084	hydrolase, TatD family'
HW10_RS02715	COG0714	Associated with various cellular activities
HW10_RS02725	COG0583	DNA-binding transcription factor activity
HW10_RS02735	COG0583	DNA-binding transcription factor activity
HW10_RS02765	COG1309	transcriptional regulator
HW10_RS02780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HW10_RS02785	COG1960	acyl-CoA dehydrogenase activity
HW10_RS02790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HW10_RS02805	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS02820	COG1595	DNA-templated transcription, initiation
HW10_RS02825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS02835	COG2197	response regulator
HW10_RS02840	COG2885	chlorophyll binding
HW10_RS02840	COG3047	cAMP biosynthetic process
HW10_RS02870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS02900	COG1120	ATPase activity
HW10_RS02910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS02940	COG0840	transmembrane signaling receptor activity
HW10_RS02945	COG0583	DNA-binding transcription factor activity
HW10_RS02950	COG1473	amidohydrolase
HW10_RS02955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS02960	COG4215	(ABC) transporter
HW10_RS02965	COG4160	amino acid transport
HW10_RS03000	COG1309	transcriptional regulator
HW10_RS03005	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS03010	COG2814	Major facilitator Superfamily
HW10_RS03030	COG3038	cytochrome b561
HW10_RS03040	COG2233	PERMEase
HW10_RS03050	COG0183	Belongs to the thiolase family
HW10_RS03065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HW10_RS03150	COG0084	hydrolase, TatD family'
HW10_RS03170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HW10_RS03180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HW10_RS03210	COG1399	metal-binding, possibly nucleic acid-binding protein
HW10_RS03220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HW10_RS03220	COG0616	signal peptide processing
HW10_RS03235	COG1530	ribonuclease E activity
HW10_RS03245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HW10_RS03265	COG0848	biopolymer transport protein
HW10_RS03270	COG0811	peptide transport
HW10_RS03275	COG0658	competence protein
HW10_RS03275	COG2333	competence protein COMEC
HW10_RS03295	COG4591	ABC-type transport system involved in lipoprotein release permease component
HW10_RS03310	COG0584	glycerophosphoryl diester phosphodiesterase
HW10_RS03325	COG1477	protein flavinylation
HW10_RS03360	COG1113	amino acid transport
HW10_RS03370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HW10_RS03445	COG0589	response to stress
HW10_RS03455	COG0488	(ABC) transporter
HW10_RS03460	COG0741	lytic transglycosylase activity
HW10_RS03480	COG1070	Carbohydrate kinase
HW10_RS03485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HW10_RS03505	COG0521	Mo-molybdopterin cofactor biosynthetic process
HW10_RS03535	COG1309	transcriptional regulator
HW10_RS03540	COG0625	glutathione transferase activity
HW10_RS03550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS03560	COG0004	ammonium transporteR
HW10_RS03585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS03585	COG2205	protein histidine kinase activity
HW10_RS03590	COG2197	response regulator
HW10_RS03595	COG3171	Protein conserved in bacteria
HW10_RS03600	COG2027	D-alanyl-D-alanine carboxypeptidase
HW10_RS03610	COG3130	regulation of translation
HW10_RS03660	COG0297	glycogen (starch) synthase activity
HW10_RS03685	COG2342	PFAM TM1410 hypothetical-related protein
HW10_RS03695	COG1335	isochorismatase
HW10_RS03715	COG0714	Associated with various cellular activities
HW10_RS03750	COG0745	RESPONSE REGULATOR receiver
HW10_RS03780	COG0308	aminopeptidase N
HW10_RS03790	COG3139	Protein of unknown function (DUF1315)
HW10_RS03800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HW10_RS03825	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS03825	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS03925	COG1286	toxin biosynthetic process
HW10_RS03930	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HW10_RS03935	COG0285	dihydrofolate synthase activity
HW10_RS03975	COG2226	methyltransferase
HW10_RS03995	COG0251	oxidation-reduction process
HW10_RS04000	COG0583	DNA-binding transcription factor activity
HW10_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS04035	COG0800	Aldolase
HW10_RS04040	COG0596	Alpha beta hydrolase
HW10_RS04075	COG0583	DNA-binding transcription factor activity
HW10_RS04115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HW10_RS04190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HW10_RS04220	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS04250	COG0786	glutamate:sodium symporter activity
HW10_RS04295	COG0676	glucose-6-phosphate 1-epimerase activity
HW10_RS04305	COG3842	ATPase activity
HW10_RS04310	COG0395	ABC-type sugar transport system, permease component
HW10_RS04315	COG1175	transmembrane transport
HW10_RS04360	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HW10_RS04370	COG0009	L-threonylcarbamoyladenylate synthase
HW10_RS04375	COG0613	PHP domain protein
HW10_RS04385	COG2350	Protein conserved in bacteria
HW10_RS04395	COG0745	RESPONSE REGULATOR receiver
HW10_RS04415	COG0778	Nitroreductase
HW10_RS04420	COG0727	PFAM Uncharacterised protein family (UPF0153)
HW10_RS04425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HW10_RS04430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HW10_RS04435	COG1127	ABC transporter
HW10_RS04465	COG0438	transferase activity, transferring glycosyl groups
HW10_RS04465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HW10_RS04480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HW10_RS04505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS04515	COG1132	(ABC) transporter
HW10_RS04545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS04550	COG3162	membrane
HW10_RS04570	COG2853	Lipoprotein
HW10_RS04585	COG1560	Kdo2-lipid A biosynthetic process
HW10_RS04595	COG2894	cell division
HW10_RS04605	COG0564	pseudouridine synthase activity
HW10_RS04635	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS04650	COG0560	Phosphoserine phosphatase
HW10_RS04655	COG3321	synthase
HW10_RS04655	COG0604	alcohol dehydrogenase
HW10_RS04665	COG2200	EAL domain
HW10_RS04715	COG0385	Bile acid
HW10_RS04720	COG2076	Multidrug Resistance protein
HW10_RS04735	COG4772	TonB-dependent receptor
HW10_RS04750	COG0784	Response regulator, receiver
HW10_RS04750	COG2205	protein histidine kinase activity
HW10_RS04755	COG1201	RNA secondary structure unwinding
HW10_RS04825	COG1595	DNA-templated transcription, initiation
HW10_RS04875	COG0537	adenosine 5'-monophosphoramidase activity
HW10_RS04885	COG1643	Atp-dependent helicase
HW10_RS04895	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS04900	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS04905	COG2267	carboxylic ester hydrolase activity
HW10_RS04910	COG2030	dehydratase
HW10_RS04915	COG2814	Major facilitator Superfamily
HW10_RS04955	COG0589	response to stress
HW10_RS04970	COG2084	Dehydrogenase
HW10_RS04975	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HW10_RS04985	COG3639	organic phosphonate transmembrane transporter activity
HW10_RS05015	COG0583	DNA-binding transcription factor activity
HW10_RS05060	COG4221	oxidoreductase activity
HW10_RS05065	COG2124	cytochrome p450
HW10_RS05105	COG1752	Esterase of the alpha-beta hydrolase superfamily
HW10_RS05125	COG4251	negative regulation of phosphorylation
HW10_RS05125	COG5001	Diguanylate cyclase
HW10_RS05125	COG2203	Gaf domain
HW10_RS05125	COG3706	GGDEF domain
HW10_RS05130	COG0514	ATP-dependent DNA helicase (RecQ)
HW10_RS05140	COG0745	RESPONSE REGULATOR receiver
HW10_RS05155	COG0835	chemotaxis
HW10_RS05155	COG0784	Response regulator, receiver
HW10_RS05175	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HW10_RS05200	COG0697	spore germination
HW10_RS05275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HW10_RS05285	COG3454	Phosphonate metabolism
HW10_RS05290	COG4778	phosphonate C-P lyase system protein PhnL
HW10_RS05295	COG4107	phosphonate C-P lyase system protein PhnK
HW10_RS05300	COG3627	carbon phosphorus lyase activity
HW10_RS05305	COG3626	phosphonate metabolism
HW10_RS05315	COG3624	Phosphonate C-P lyase system protein PhnG
HW10_RS05320	COG2188	Transcriptional regulator
HW10_RS05325	COG3639	organic phosphonate transmembrane transporter activity
HW10_RS05330	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HW10_RS05405	COG0583	DNA-binding transcription factor activity
HW10_RS05460	COG1629	transport
HW10_RS05500	COG0508	dehydrogenase complex catalyzes the overall conversion of
HW10_RS05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HW10_RS05555	COG1024	Enoyl-CoA hydratase
HW10_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS05580	COG1346	cytolysis
HW10_RS05585	COG1380	Effector of murein hydrolase LrgA
HW10_RS05590	COG0583	DNA-binding transcription factor activity
HW10_RS05615	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HW10_RS05640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS05650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS05655	COG0431	NADPH-dependent FMN reductase
HW10_RS05665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS05670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS05675	COG0450	alkyl hydroperoxide reductase
HW10_RS05695	COG0183	Belongs to the thiolase family
HW10_RS05720	COG0367	asparagine synthase
HW10_RS05725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HW10_RS05725	COG0189	ligase activity
HW10_RS05730	COG1363	Peptidase, m42
HW10_RS05735	COG0784	Response regulator, receiver
HW10_RS05735	COG2205	protein histidine kinase activity
HW10_RS05735	COG5002	protein histidine kinase activity
HW10_RS05755	COG0513	Belongs to the DEAD box helicase family
HW10_RS05760	COG0477	Major facilitator Superfamily
HW10_RS05765	COG0668	transmembrane transport
HW10_RS05770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HW10_RS05785	COG0791	NLP P60 protein
HW10_RS05830	COG0489	protein tyrosine kinase activity
HW10_RS05885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HW10_RS05895	COG2264	protein methyltransferase activity
HW10_RS05900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HW10_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS05965	COG0450	alkyl hydroperoxide reductase
HW10_RS05980	COG2223	nitrite transmembrane transporter activity
HW10_RS05985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HW10_RS05990	COG0243	molybdopterin cofactor binding
HW10_RS06010	COG3842	ATPase activity
HW10_RS06120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HW10_RS06120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HW10_RS06120	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HW10_RS06125	COG1105	Belongs to the carbohydrate kinase PfkB family
HW10_RS06135	COG1609	Transcriptional regulator
HW10_RS06140	COG0084	hydrolase, TatD family'
HW10_RS06150	COG0583	DNA-binding transcription factor activity
HW10_RS06190	COG2814	Major facilitator Superfamily
HW10_RS06235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HW10_RS06270	COG0583	DNA-binding transcription factor activity
HW10_RS06280	COG0183	Belongs to the thiolase family
HW10_RS06285	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS06290	COG1024	Enoyl-CoA hydratase
HW10_RS06295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW10_RS06300	COG1960	acyl-CoA dehydrogenase activity
HW10_RS06305	COG0583	DNA-binding transcription factor activity
HW10_RS06310	COG0477	Major facilitator Superfamily
HW10_RS06315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW10_RS06315	COG2169	Transcriptional regulator
HW10_RS06320	COG0531	amino acid
HW10_RS06345	COG0069	glutamate synthase activity
HW10_RS06365	COG3148	PFAM DTW domain containing protein
HW10_RS06375	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS06380	COG1177	transmembrane transport
HW10_RS06395	COG3530	Putative quorum-sensing-regulated virulence factor
HW10_RS06400	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HW10_RS06405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HW10_RS06425	COG1546	Belongs to the CinA family
HW10_RS06475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HW10_RS06480	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HW10_RS06485	COG0583	DNA-binding transcription factor activity
HW10_RS06490	COG2391	methyltransferase activity
HW10_RS06540	COG1115	amino acid carrier protein
HW10_RS06620	COG0024	Methionine aminopeptidase
HW10_RS06630	COG0436	Aminotransferase
HW10_RS06635	COG0025	NhaP-type Na H and K H
HW10_RS06655	COG1393	Belongs to the ArsC family
HW10_RS06660	COG1280	lysine exporter protein (LysE YggA)
HW10_RS06675	COG2166	iron-sulfur cluster assembly
HW10_RS06720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS06745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HW10_RS06750	COG1801	Protein of unknown function DUF72
HW10_RS06760	COG1214	PFAM Peptidase M22, glycoprotease
HW10_RS06780	COG0789	Transcriptional regulator
HW10_RS06795	COG2885	chlorophyll binding
HW10_RS06810	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HW10_RS06810	COG3064	Membrane
HW10_RS06810	COG1073	alpha beta
HW10_RS06840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HW10_RS06845	COG3706	GGDEF domain
HW10_RS06845	COG4251	negative regulation of phosphorylation
HW10_RS06845	COG5001	Diguanylate cyclase
HW10_RS06845	COG2203	Gaf domain
HW10_RS06880	COG0477	Major facilitator Superfamily
HW10_RS06900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HW10_RS06905	COG2197	response regulator
HW10_RS06950	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS06960	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HW10_RS07000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW10_RS07025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HW10_RS07045	COG1607	acyl-coa hydrolase
HW10_RS07070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HW10_RS07080	COG4536	flavin adenine dinucleotide binding
HW10_RS07085	COG0477	Major facilitator Superfamily
HW10_RS07125	COG2188	Transcriptional regulator
HW10_RS07130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HW10_RS07135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HW10_RS07140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HW10_RS07140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HW10_RS07175	COG0590	tRNA wobble adenosine to inosine editing
HW10_RS07180	COG2132	Multicopper oxidase
HW10_RS07230	COG0583	DNA-binding transcription factor activity
HW10_RS07235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HW10_RS07245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HW10_RS07260	COG1335	isochorismatase
HW10_RS07270	COG2847	Copper chaperone PCu(A)C
HW10_RS07280	COG0739	heme binding
HW10_RS07320	COG0667	Aldo Keto reductase
HW10_RS07335	COG0436	Aminotransferase
HW10_RS07425	COG1045	serine acetyltransferase
HW10_RS07440	COG3134	Outer membrane lipoprotein
HW10_RS07455	COG1862	Preprotein translocase
HW10_RS07475	COG2200	EAL domain
HW10_RS07485	COG0795	lipopolysaccharide-transporting ATPase activity
HW10_RS07490	COG0795	lipopolysaccharide-transporting ATPase activity
HW10_RS07535	COG4120	Belongs to the binding-protein-dependent transport system permease family
HW10_RS07540	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HW10_RS07545	COG0490	domain, Protein
HW10_RS07545	COG0471	metal ion transport
HW10_RS07575	COG0583	DNA-binding transcription factor activity
HW10_RS07640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS07650	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS07675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS07685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS07690	COG2181	nitrate reductase activity
HW10_RS07695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HW10_RS07700	COG1140	nitrate reductase beta subunit
HW10_RS07705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HW10_RS07710	COG2223	nitrite transmembrane transporter activity
HW10_RS07720	COG3850	Histidine kinase
HW10_RS07725	COG2197	response regulator
HW10_RS07740	COG2226	methyltransferase
HW10_RS07745	COG0300	oxidoreductase activity
HW10_RS07795	COG1566	PFAM secretion protein HlyD family protein
HW10_RS07815	COG0583	DNA-binding transcription factor activity
HW10_RS07825	COG0697	spore germination
HW10_RS07835	COG1595	DNA-templated transcription, initiation
HW10_RS07840	COG3712	iron ion homeostasis
HW10_RS07845	COG4772	TonB-dependent receptor
HW10_RS07895	COG3154	lipid carrier protein
HW10_RS07900	COG0826	peptidase U32
HW10_RS07905	COG0826	peptidase U32
HW10_RS07910	COG0303	'Molybdopterin
HW10_RS07915	COG0521	Mo-molybdopterin cofactor biosynthetic process
HW10_RS07925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HW10_RS07935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HW10_RS07960	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS07965	COG0183	Belongs to the thiolase family
HW10_RS07975	COG2207	Transcriptional regulator
HW10_RS07985	COG1294	oxidase, subunit
HW10_RS07990	COG1271	oxidase subunit
HW10_RS08005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW10_RS08010	COG1297	OPT oligopeptide transporter protein
HW10_RS08015	COG2175	clavaminate synthase activity
HW10_RS08020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS08030	COG4521	taurine ABC transporter
HW10_RS08050	COG1946	Acyl-CoA thioesterase
HW10_RS08070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS08070	COG2205	protein histidine kinase activity
HW10_RS08075	COG2202	Pas domain
HW10_RS08075	COG2200	EAL domain
HW10_RS08075	COG2199	diguanylate cyclase activity
HW10_RS08080	COG2197	response regulator
HW10_RS08090	COG0513	Belongs to the DEAD box helicase family
HW10_RS08100	COG3416	Protein conserved in bacteria
HW10_RS08125	COG0300	oxidoreductase activity
HW10_RS08170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS08175	COG1074	ATP-dependent DNA helicase activity
HW10_RS08195	COG1061	Type III restriction enzyme res subunit
HW10_RS08225	COG1643	Atp-dependent helicase
HW10_RS08235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HW10_RS08275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HW10_RS08285	COG1960	acyl-CoA dehydrogenase activity
HW10_RS08295	COG0784	Response regulator, receiver
HW10_RS08295	COG2205	protein histidine kinase activity
HW10_RS08295	COG2198	Histidine kinase
HW10_RS08300	COG0351	phosphomethylpyrimidine kinase
HW10_RS08330	COG1702	phosphate starvation-inducible protein PhoH
HW10_RS08340	COG4535	Mg2 and Co2 transporter CorC
HW10_RS08350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HW10_RS08390	COG2951	lytic endotransglycosylase activity
HW10_RS08420	COG1686	Belongs to the peptidase S11 family
HW10_RS08430	COG2951	lytic endotransglycosylase activity
HW10_RS08435	COG0772	Belongs to the SEDS family
HW10_RS08440	COG0768	penicillin binding
HW10_RS08480	COG0586	Pfam SNARE associated Golgi protein
HW10_RS08490	COG1346	cytolysis
HW10_RS08510	COG0702	epimerase
HW10_RS08525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HW10_RS08530	COG3284	Transcriptional regulator
HW10_RS08540	COG0531	amino acid
HW10_RS08545	COG4303	Ethanolamine ammonia lyase large subunit
HW10_RS08555	COG0456	acetyltransferase
HW10_RS08570	COG0586	Pfam SNARE associated Golgi protein
HW10_RS08575	COG3228	Belongs to the MtfA family
HW10_RS08585	COG0745	RESPONSE REGULATOR receiver
HW10_RS08605	COG5002	protein histidine kinase activity
HW10_RS08610	COG1131	(ABC) transporter
HW10_RS08630	COG4948	Mandelate Racemase Muconate Lactonizing
HW10_RS08640	COG0142	geranyltranstransferase activity
HW10_RS08665	COG3577	Aspartyl protease
HW10_RS08675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HW10_RS08680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HW10_RS08705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HW10_RS08705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HW10_RS08720	COG2264	protein methyltransferase activity
HW10_RS08725	COG3118	belongs to the thioredoxin family
HW10_RS08755	COG3047	cAMP biosynthetic process
HW10_RS08765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HW10_RS08785	COG0531	amino acid
HW10_RS08825	COG2197	response regulator
HW10_RS08835	COG3210	domain, Protein
HW10_RS08840	COG3121	Chaperone
HW10_RS08845	COG3188	usher protein
HW10_RS08850	COG3121	Chaperone
HW10_RS08865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HW10_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS08905	COG2271	Major facilitator Superfamily
HW10_RS08910	COG1063	alcohol dehydrogenase
HW10_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS08940	COG2205	protein histidine kinase activity
HW10_RS08950	COG2259	Doxx family
HW10_RS09010	COG1611	Belongs to the LOG family
HW10_RS09050	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS09055	COG3384	dioxygenase
HW10_RS09065	COG2271	Major facilitator Superfamily
HW10_RS09070	COG3971	2-oxopent-4-enoate hydratase activity
HW10_RS09085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS09095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS09100	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS09110	COG1846	Transcriptional regulator
HW10_RS09115	COG2814	Major facilitator Superfamily
HW10_RS09145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS09170	COG3284	Transcriptional regulator
HW10_RS09180	COG3199	ATP-NAD kinase
HW10_RS09185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HW10_RS09190	COG0022	dehydrogenase e1 component
HW10_RS09200	COG1063	alcohol dehydrogenase
HW10_RS09205	COG4991	sh3 domain protein
HW10_RS09210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS09215	COG1629	transport
HW10_RS09215	COG4774	siderophore transport
HW10_RS09225	COG1120	ATPase activity
HW10_RS09230	COG4592	Periplasmic binding protein
HW10_RS09235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS09240	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS09250	COG0154	amidase activity
HW10_RS09280	COG1959	2 iron, 2 sulfur cluster binding
HW10_RS09285	COG0492	ferredoxin-NADP+ reductase activity
HW10_RS09290	COG0693	protein deglycase activity
HW10_RS09300	COG0251	oxidation-reduction process
HW10_RS09315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS09325	COG2226	methyltransferase
HW10_RS09370	COG2271	Major facilitator Superfamily
HW10_RS09375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS09400	COG0765	amino acid transport
HW10_RS09405	COG0765	amino acid transport
HW10_RS09410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS09415	COG4566	intracellular signal transduction
HW10_RS09420	COG4191	Histidine kinase
HW10_RS09430	COG1960	acyl-CoA dehydrogenase activity
HW10_RS09435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS09455	COG2706	6-phosphogluconolactonase activity
HW10_RS09465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS09470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS09550	COG1132	(ABC) transporter
HW10_RS09550	COG2375	cellular response to nickel ion
HW10_RS09560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS09560	COG2226	methyltransferase
HW10_RS09560	COG3433	isochorismatase activity
HW10_RS09565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS09565	COG2226	methyltransferase
HW10_RS09565	COG3433	isochorismatase activity
HW10_RS09575	COG1021	2,3-dihydroxybenzoate-AMP ligase
HW10_RS09600	COG2814	Major facilitator Superfamily
HW10_RS09725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HW10_RS09890	COG0739	heme binding
HW10_RS09920	COG1981	membrane
HW10_RS09935	COG0300	oxidoreductase activity
HW10_RS09945	COG0537	adenosine 5'-monophosphoramidase activity
HW10_RS09960	COG1765	OsmC-like protein
HW10_RS09995	COG3179	chitinase
HW10_RS10080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW10_RS10105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HW10_RS10115	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS10125	COG3842	ATPase activity
HW10_RS10135	COG2197	response regulator
HW10_RS10150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HW10_RS10200	COG2766	serine protein kinase
HW10_RS10210	COG2719	SpoVR family
HW10_RS10230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HW10_RS10325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS10330	COG4977	sequence-specific DNA binding
HW10_RS10330	COG1917	Cupin 2, conserved barrel domain protein
HW10_RS10335	COG3152	Membrane
HW10_RS10340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HW10_RS10350	COG1451	nucleotide metabolic process
HW10_RS10355	COG2081	HI0933 family
HW10_RS10395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HW10_RS10400	COG3622	Belongs to the hyi family
HW10_RS10410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HW10_RS10415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS10470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HW10_RS10480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS10500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HW10_RS10510	COG2258	MOSC domain
HW10_RS10515	COG0583	DNA-binding transcription factor activity
HW10_RS10520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HW10_RS10605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HW10_RS10605	COG1648	precorrin-2 dehydrogenase activity
HW10_RS10615	COG1960	acyl-CoA dehydrogenase activity
HW10_RS10620	COG1960	acyl-CoA dehydrogenase activity
HW10_RS10625	COG1960	acyl-CoA dehydrogenase activity
HW10_RS10645	COG1073	alpha beta
HW10_RS10645	COG2226	methyltransferase
HW10_RS10660	COG3121	Chaperone
HW10_RS10670	COG1984	allophanate hydrolase subunit 2
HW10_RS10685	COG0511	ligase activity, forming carbon-carbon bonds
HW10_RS10705	COG1040	competence protein
HW10_RS10710	COG5544	Lipoprotein
HW10_RS10715	COG3585	molybdate ion transport
HW10_RS10715	COG2005	Transcriptional regulator
HW10_RS10750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS10770	COG1953	Uracil, thiamine, allantoin
HW10_RS10775	COG1309	transcriptional regulator
HW10_RS10785	COG0625	glutathione transferase activity
HW10_RS10790	COG1595	DNA-templated transcription, initiation
HW10_RS10795	COG3712	iron ion homeostasis
HW10_RS10800	COG4774	siderophore transport
HW10_RS10830	COG4452	Inner membrane protein CreD
HW10_RS10835	COG2205	protein histidine kinase activity
HW10_RS10840	COG0745	RESPONSE REGULATOR receiver
HW10_RS10850	COG0204	Acyl-transferase
HW10_RS10860	COG0542	response to heat
HW10_RS10865	COG0477	Major facilitator Superfamily
HW10_RS10875	COG4067	protein conserved in archaea
HW10_RS10875	COG0189	ligase activity
HW10_RS10885	COG0513	Belongs to the DEAD box helicase family
HW10_RS10890	COG1289	transmembrane transporter activity
HW10_RS10900	COG0330	HflC and HflK could
HW10_RS10920	COG0583	DNA-binding transcription factor activity
HW10_RS10925	COG1960	acyl-CoA dehydrogenase activity
HW10_RS10940	COG1953	Uracil, thiamine, allantoin
HW10_RS10965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HW10_RS10970	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS10975	COG1309	transcriptional regulator
HW10_RS11000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW10_RS11005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HW10_RS11015	COG0513	Belongs to the DEAD box helicase family
HW10_RS11045	COG3038	cytochrome b561
HW10_RS11060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HW10_RS11090	COG0643	Histidine kinase
HW10_RS11090	COG0784	Response regulator, receiver
HW10_RS11090	COG2198	Histidine kinase
HW10_RS11155	COG0626	cystathionine gamma-synthase activity
HW10_RS11200	COG1872	DUF167
HW10_RS11205	COG1160	GTP binding
HW10_RS11215	COG2813	Specifically methylates the guanine in position
HW10_RS11215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS11230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HW10_RS11265	COG2363	Small membrane protein
HW10_RS11285	COG2177	Part of the ABC transporter FtsEX involved in
HW10_RS11290	COG2884	Cell division ATP-binding protein ftsE
HW10_RS11295	COG0552	protein localization to endoplasmic reticulum
HW10_RS11300	COG0612	Peptidase, M16
HW10_RS11305	COG0612	Peptidase, M16
HW10_RS11310	COG0742	ribosomal rna small subunit methyltransferase
HW10_RS11320	COG0429	hydrolase of the alpha beta-hydrolase fold
HW10_RS11345	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW10_RS11355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW10_RS11390	COG0693	protein deglycase activity
HW10_RS11405	COG2233	PERMEase
HW10_RS11410	COG0622	Phosphoesterase
HW10_RS11430	COG0584	glycerophosphoryl diester phosphodiesterase
HW10_RS11465	COG0730	response to heat
HW10_RS11505	COG0702	epimerase
HW10_RS11515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HW10_RS11535	COG2234	aminopeptidase activity
HW10_RS11540	COG3204	pilus organization
HW10_RS11545	COG3842	ATPase activity
HW10_RS11555	COG1177	transmembrane transport
HW10_RS11560	COG2182	Extracellular solute-binding protein
HW10_RS11565	COG0531	amino acid
HW10_RS11575	COG3111	PFAM Bacterial OB fold (BOF) protein
HW10_RS11585	COG0179	Fumarylacetoacetate (FAA) hydrolase
HW10_RS11590	COG0277	FAD linked oxidase domain protein
HW10_RS11595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HW10_RS11610	COG0765	amino acid transport
HW10_RS11660	COG1177	transmembrane transport
HW10_RS11665	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS11670	COG3842	ATPase activity
HW10_RS11690	COG0174	glutamine synthetase
HW10_RS11695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HW10_RS11700	COG0174	glutamine synthetase
HW10_RS11705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HW10_RS11730	COG2199	diguanylate cyclase activity
HW10_RS11765	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HW10_RS11775	COG4208	sulfate ABC transporter
HW10_RS11795	COG0501	Belongs to the peptidase M48B family
HW10_RS11815	COG2807	transmembrane transport
HW10_RS11820	COG0583	DNA-binding transcription factor activity
HW10_RS11835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS11845	COG0745	RESPONSE REGULATOR receiver
HW10_RS11920	COG2963	transposase activity
HW10_RS11965	COG2239	Acts as a magnesium transporter
HW10_RS11985	COG0477	Major facilitator Superfamily
HW10_RS11995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HW10_RS12000	COG1309	transcriptional regulator
HW10_RS12010	COG2271	Major facilitator Superfamily
HW10_RS12030	COG0673	inositol 2-dehydrogenase activity
HW10_RS12050	COG0583	DNA-binding transcription factor activity
HW10_RS12055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS12060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS12070	COG0477	Major facilitator Superfamily
HW10_RS12080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HW10_RS12085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HW10_RS12090	COG1396	sequence-specific DNA binding
HW10_RS12095	COG0235	Class ii aldolase
HW10_RS12100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS12115	COG1113	amino acid transport
HW10_RS12120	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS12150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HW10_RS12225	COG2175	clavaminate synthase activity
HW10_RS12265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS12270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS12275	COG1116	anion transmembrane transporter activity
HW10_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS12290	COG0583	DNA-binding transcription factor activity
HW10_RS12300	COG0745	RESPONSE REGULATOR receiver
HW10_RS12305	COG2198	Histidine kinase
HW10_RS12305	COG0643	Histidine kinase
HW10_RS12310	COG0835	chemotaxis
HW10_RS12325	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HW10_RS12360	COG1309	transcriptional regulator
HW10_RS12365	COG2233	PERMEase
HW10_RS12400	COG0583	DNA-binding transcription factor activity
HW10_RS12405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS12420	COG1414	Transcriptional regulator
HW10_RS12425	COG3485	protocatechuate 3,4-dioxygenase
HW10_RS12430	COG3485	protocatechuate 3,4-dioxygenase
HW10_RS12435	COG0583	DNA-binding transcription factor activity
HW10_RS12505	COG1079	Belongs to the binding-protein-dependent transport system permease family
HW10_RS12510	COG4603	Belongs to the binding-protein-dependent transport system permease family
HW10_RS12515	COG3845	ABC transporter
HW10_RS12525	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS12555	COG2824	Alkylphosphonate utilization operon protein PhnA
HW10_RS12580	COG0583	DNA-binding transcription factor activity
HW10_RS12620	COG2153	protein acetylation
HW10_RS12660	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HW10_RS12665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HW10_RS12670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HW10_RS12680	COG0659	secondary active sulfate transmembrane transporter activity
HW10_RS12805	COG1360	Flagellar Motor Protein
HW10_RS12820	COG0631	protein serine/threonine phosphatase activity
HW10_RS12825	COG0515	serine threonine protein kinase
HW10_RS12825	COG2815	serine threonine protein kinase
HW10_RS12840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HW10_RS12855	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HW10_RS12860	COG0339	signal peptide processing
HW10_RS12865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HW10_RS12900	COG1764	response to oxidative stress
HW10_RS12915	COG0583	DNA-binding transcription factor activity
HW10_RS12940	COG0367	asparagine synthase
HW10_RS12980	COG3174	membrane
HW10_RS13020	COG3360	Dodecin
HW10_RS13055	COG0583	DNA-binding transcription factor activity
HW10_RS13060	COG3119	arylsulfatase activity
HW10_RS13080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS13110	COG0758	DNA mediated transformation
HW10_RS13115	COG1652	LysM domain
HW10_RS13135	COG0569	domain protein
HW10_RS13150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HW10_RS13165	COG2818	Glycosylase
HW10_RS13180	COG2010	Cytochrome c
HW10_RS13250	COG1192	Involved in chromosome partitioning
HW10_RS13255	COG1475	DNA binding
HW10_RS13315	COG1349	DNA-binding transcription factor activity
HW10_RS13335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HW10_RS13340	COG2358	TRAP transporter, solute receptor (TAXI family
HW10_RS13360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HW10_RS13375	COG0860	N-Acetylmuramoyl-L-alanine amidase
HW10_RS13405	COG0523	cobalamin synthesis protein
HW10_RS13415	COG0477	Major facilitator Superfamily
HW10_RS13420	COG4651	solute:proton antiporter activity
HW10_RS13420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW10_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS13450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HW10_RS13455	COG0174	glutamine synthetase
HW10_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS13470	COG1607	acyl-coa hydrolase
HW10_RS13475	COG4651	solute:proton antiporter activity
HW10_RS13475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW10_RS13510	COG4191	Histidine kinase
HW10_RS13520	COG0531	amino acid
HW10_RS13550	COG2011	ABC-type metal ion transport system permease component
HW10_RS13565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HW10_RS13575	COG0735	belongs to the Fur family
HW10_RS13580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HW10_RS13615	COG3245	cytochrome
HW10_RS13640	COG2095	MarC family integral membrane protein
HW10_RS13645	COG3023	N-Acetylmuramoyl-L-alanine amidase
HW10_RS13650	COG5002	protein histidine kinase activity
HW10_RS13675	COG1301	dicarboxylic acid transport
HW10_RS13680	COG0700	Nucleoside recognition
HW10_RS13715	COG1690	Belongs to the RtcB family
HW10_RS13720	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HW10_RS13725	COG0861	Integral membrane protein TerC family
HW10_RS13730	COG2851	Citrate transporter
HW10_RS13740	COG0679	Auxin Efflux Carrier
HW10_RS13780	COG2755	lipolytic protein G-D-S-L family
HW10_RS13780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HW10_RS13785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS13830	COG0438	transferase activity, transferring glycosyl groups
HW10_RS13845	COG0427	acetyl-CoA hydrolase
HW10_RS13855	COG0210	DNA helicase
HW10_RS13875	COG0826	peptidase U32
HW10_RS13880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HW10_RS13895	COG0583	DNA-binding transcription factor activity
HW10_RS13900	COG0439	Biotin carboxylase
HW10_RS13905	COG5016	pyruvate
HW10_RS13905	COG0511	ligase activity, forming carbon-carbon bonds
HW10_RS13930	COG2391	methyltransferase activity
HW10_RS13940	COG0583	DNA-binding transcription factor activity
HW10_RS14025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HW10_RS14025	COG1017	nitric oxide dioxygenase activity
HW10_RS14065	COG3655	Transcriptional regulator
HW10_RS14085	COG0247	lactate metabolic process
HW10_RS14085	COG2181	nitrate reductase activity
HW10_RS14090	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS14090	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS14145	COG3246	L-lysine catabolic process to acetate
HW10_RS14160	COG0657	acetylesterase activity
HW10_RS14170	COG0583	DNA-binding transcription factor activity
HW10_RS14185	COG1760	l-serine dehydratase
HW10_RS14195	COG4176	ABC-type proline glycine betaine transport system permease component
HW10_RS14200	COG4175	Glycine betaine
HW10_RS14205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW10_RS14225	COG1607	acyl-coa hydrolase
HW10_RS14230	COG0477	Major facilitator Superfamily
HW10_RS14290	COG0739	heme binding
HW10_RS14295	COG1253	flavin adenine dinucleotide binding
HW10_RS14325	COG2186	Transcriptional regulator
HW10_RS14330	COG0277	FAD linked oxidase domain protein
HW10_RS14335	COG0277	FAD linked oxidase domain protein
HW10_RS14340	COG0247	lactate metabolic process
HW10_RS14345	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HW10_RS14380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HW10_RS14385	COG0583	DNA-binding transcription factor activity
HW10_RS14395	COG4753	response regulator
HW10_RS14395	COG2207	Transcriptional regulator
HW10_RS14415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW10_RS14430	COG1561	YicC-like family, N-terminal region
HW10_RS14445	COG0708	Exodeoxyribonuclease III
HW10_RS14465	COG3245	cytochrome
HW10_RS14505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HW10_RS14520	COG0747	negative chemotaxis
HW10_RS14540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HW10_RS14545	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS14550	COG2814	Major facilitator Superfamily
HW10_RS14555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW10_RS14560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS14590	COG0251	oxidation-reduction process
HW10_RS14600	COG1917	Cupin 2, conserved barrel domain protein
HW10_RS14600	COG1396	sequence-specific DNA binding
HW10_RS14610	COG0427	acetyl-CoA hydrolase
HW10_RS14620	COG0028	Belongs to the TPP enzyme family
HW10_RS14625	COG0210	DNA helicase
HW10_RS14640	COG0583	DNA-binding transcription factor activity
HW10_RS14650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW10_RS14655	COG0606	chelatase, subunit chli
HW10_RS14665	COG0347	Belongs to the P(II) protein family
HW10_RS14670	COG0004	ammonium transporteR
HW10_RS14675	COG0432	Pfam Uncharacterised protein family UPF0047
HW10_RS14735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HW10_RS14765	COG0598	Magnesium transport protein CorA
HW10_RS14795	COG3275	phosphorelay sensor kinase activity
HW10_RS14850	COG0488	(ABC) transporter
HW10_RS14860	COG0861	Integral membrane protein TerC family
HW10_RS14865	COG1280	lysine exporter protein (LysE YggA)
HW10_RS14870	COG0672	)-iron permease
HW10_RS14880	COG2050	protein possibly involved in aromatic compounds catabolism
HW10_RS14885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HW10_RS14890	COG0586	Pfam SNARE associated Golgi protein
HW10_RS14920	COG2755	lipolytic protein G-D-S-L family
HW10_RS14920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HW10_RS14935	COG2271	Major facilitator Superfamily
HW10_RS14950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS14955	COG1129	ABC transporter
HW10_RS14955	COG0842	Transport permease protein
HW10_RS14960	COG0842	Transport permease protein
HW10_RS14970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HW10_RS14995	COG0006	proline dipeptidase activity
HW10_RS15000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW10_RS15010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW10_RS15025	COG0583	DNA-binding transcription factor activity
HW10_RS15035	COG1178	ABC-type Fe3 transport system permease component
HW10_RS15065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW10_RS15070	COG3025	triphosphatase activity
HW10_RS15075	COG1392	Phosphate transport regulator
HW10_RS15080	COG0306	phosphate transporter
HW10_RS15110	COG2183	response to ionizing radiation
HW10_RS15135	COG4067	protein conserved in archaea
HW10_RS15135	COG0189	ligase activity
HW10_RS15140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HW10_RS15165	COG0778	Nitroreductase
HW10_RS15175	COG1024	Enoyl-CoA hydratase
HW10_RS15175	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS15180	COG1960	acyl-CoA dehydrogenase activity
HW10_RS15185	COG1454	alcohol dehydrogenase
HW10_RS15190	COG0824	Thioesterase
HW10_RS15200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HW10_RS15220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HW10_RS15230	COG1652	LysM domain
HW10_RS15235	COG1011	Hydrolase
HW10_RS15240	COG0494	nUDIX hydrolase
HW10_RS15245	COG1218	3'(2'),5'-bisphosphate nucleotidase
HW10_RS15310	COG1091	dTDP-4-dehydrorhamnose reductase activity
HW10_RS15315	COG1088	dTDP-glucose 4,6-dehydratase activity
HW10_RS15325	COG2814	Major facilitator Superfamily
HW10_RS15330	COG1566	PFAM secretion protein HlyD family protein
HW10_RS15340	COG1846	Transcriptional regulator
HW10_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS15385	COG0673	inositol 2-dehydrogenase activity
HW10_RS15395	COG1194	a g-specific adenine glycosylase
HW10_RS15405	COG0579	oxidoreductase
HW10_RS15465	COG2861	carbohydrate metabolic process
HW10_RS15470	COG0793	Belongs to the peptidase S41A family
HW10_RS15475	COG4942	peptidase
HW10_RS15505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HW10_RS15520	COG3852	Histidine kinase
HW10_RS15535	COG0668	transmembrane transport
HW10_RS15555	COG1217	gtp-binding protein TYPA
HW10_RS15560	COG0789	Transcriptional regulator
HW10_RS15610	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS15645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HW10_RS15665	COG4176	ABC-type proline glycine betaine transport system permease component
HW10_RS15670	COG4175	Glycine betaine
HW10_RS15675	COG2986	histidine ammonia-lyase
HW10_RS15720	COG0251	oxidation-reduction process
HW10_RS15725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS15730	COG1051	belongs to the nudix hydrolase family
HW10_RS15760	COG0765	amino acid transport
HW10_RS15765	COG1126	abc transporter atp-binding protein
HW10_RS15775	COG0840	transmembrane signaling receptor activity
HW10_RS15885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HW10_RS15905	COG0281	malic enzyme
HW10_RS15955	COG0070	glutamate synthase
HW10_RS15955	COG0069	glutamate synthase activity
HW10_RS15955	COG0067	glutamate synthase
HW10_RS15960	COG0493	'glutamate synthase
HW10_RS15985	COG2814	Major facilitator Superfamily
HW10_RS15990	COG0583	DNA-binding transcription factor activity
HW10_RS16010	COG2873	o-acetylhomoserine
HW10_RS16015	COG0730	response to heat
HW10_RS16025	COG3264	Mechanosensitive ion channel
HW10_RS16025	COG1196	nuclear chromosome segregation
HW10_RS16035	COG1960	acyl-CoA dehydrogenase activity
HW10_RS16040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HW10_RS16075	COG0859	PFAM glycosyl transferase family 9
HW10_RS16080	COG0859	PFAM glycosyl transferase family 9
HW10_RS16085	COG0438	transferase activity, transferring glycosyl groups
HW10_RS16110	COG2192	nodulation
HW10_RS16115	COG0438	transferase activity, transferring glycosyl groups
HW10_RS16135	COG1215	transferase activity, transferring glycosyl groups
HW10_RS16160	COG1960	acyl-CoA dehydrogenase activity
HW10_RS16165	COG1960	acyl-CoA dehydrogenase activity
HW10_RS16175	COG0667	Aldo Keto reductase
HW10_RS16190	COG0583	DNA-binding transcription factor activity
HW10_RS16195	COG1519	Transferase
HW10_RS16205	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS16205	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS16235	COG0833	amino acid
HW10_RS16240	COG1024	Enoyl-CoA hydratase
HW10_RS16245	COG1960	acyl-CoA dehydrogenase activity
HW10_RS16250	COG0045	succinate-CoA ligase (ADP-forming) activity
HW10_RS16265	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW10_RS16270	COG1538	Outer membrane efflux protein
HW10_RS16285	COG0494	nUDIX hydrolase
HW10_RS16295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HW10_RS16300	COG3150	esterase
HW10_RS16315	COG3577	Aspartyl protease
HW10_RS16330	COG1988	membrane-bound metal-dependent
HW10_RS16340	COG3830	Belongs to the UPF0237 family
HW10_RS16340	COG0560	Phosphoserine phosphatase
HW10_RS16345	COG5001	Diguanylate cyclase
HW10_RS16345	COG3300	MHYT domain
HW10_RS16395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HW10_RS16395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HW10_RS16400	COG0802	atpase or kinase
HW10_RS16405	COG0860	N-Acetylmuramoyl-L-alanine amidase
HW10_RS16425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HW10_RS16430	COG0330	HflC and HflK could
HW10_RS16435	COG0330	HflC and HflK could
HW10_RS16465	COG0557	exoribonuclease II activity
HW10_RS16495	COG0305	Participates in initiation and elongation during chromosome replication
HW10_RS16510	COG3300	MHYT domain
HW10_RS16510	COG5001	Diguanylate cyclase
HW10_RS16530	COG0668	transmembrane transport
HW10_RS16570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HW10_RS16585	COG0583	DNA-binding transcription factor activity
HW10_RS16615	COG2423	ornithine cyclodeaminase activity
HW10_RS16620	COG4221	oxidoreductase activity
HW10_RS16645	COG0583	DNA-binding transcription factor activity
HW10_RS16655	COG2814	Major facilitator Superfamily
HW10_RS16675	COG1595	DNA-templated transcription, initiation
HW10_RS16680	COG3712	iron ion homeostasis
HW10_RS16740	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HW10_RS16745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HW10_RS16755	COG2193	ferroxidase activity
HW10_RS16760	COG2982	Protein involved in outer membrane biogenesis
HW10_RS16765	COG0789	Transcriptional regulator
HW10_RS16790	COG0443	Heat shock 70 kDa protein
HW10_RS16805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW10_RS16850	COG0411	ABC transporter
HW10_RS16865	COG0683	leucine binding
HW10_RS16870	COG2095	MarC family integral membrane protein
HW10_RS16955	COG0023	Translation Initiation Factor
HW10_RS16990	COG1272	protein, Hemolysin III
HW10_RS16995	COG4221	oxidoreductase activity
HW10_RS17020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HW10_RS17045	COG1283	sodium-dependent phosphate transmembrane transporter activity
HW10_RS17055	COG0534	Mate efflux family protein
HW10_RS17065	COG0463	Glycosyl transferase, family 2
HW10_RS17090	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS17090	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS17095	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HW10_RS17100	COG0243	molybdopterin cofactor binding
HW10_RS17100	COG3383	formate dehydrogenase (NAD+) activity
HW10_RS17105	COG3383	formate dehydrogenase (NAD+) activity
HW10_RS17105	COG0243	molybdopterin cofactor binding
HW10_RS17110	COG0437	4 iron, 4 sulfur cluster binding
HW10_RS17115	COG2864	formate dehydrogenase
HW10_RS17130	COG3276	selenocysteine insertion sequence binding
HW10_RS17145	COG0531	amino acid
HW10_RS17185	COG0509	glycine decarboxylation via glycine cleavage system
HW10_RS17215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS17235	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS17245	COG1522	sequence-specific DNA binding
HW10_RS17250	COG0697	spore germination
HW10_RS17270	COG0697	spore germination
HW10_RS17320	COG1620	l-lactate permease
HW10_RS17325	COG2186	Transcriptional regulator
HW10_RS17355	COG0497	DNA recombination
HW10_RS17420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HW10_RS17455	COG0195	Participates in both transcription termination and antitermination
HW10_RS17555	COG4191	Histidine kinase
HW10_RS17570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW10_RS17575	COG0436	Aminotransferase
HW10_RS17600	COG2321	neutral zinc metallopeptidase
HW10_RS17610	COG0436	Aminotransferase
HW10_RS17635	COG4771	TonB-dependent receptor
HW10_RS17640	COG3720	iron ion transport
HW10_RS17645	COG4558	Periplasmic binding protein
HW10_RS17650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS17685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HW10_RS17695	COG3098	single-species biofilm formation
HW10_RS17705	COG0028	Belongs to the TPP enzyme family
HW10_RS17720	COG1183	phosphatidylcholine synthase activity
HW10_RS17760	COG2995	paraquat-inducible protein a
HW10_RS17765	COG2995	paraquat-inducible protein a
HW10_RS17770	COG3008	intermembrane lipid transfer
HW10_RS17775	COG1178	ABC-type Fe3 transport system permease component
HW10_RS17780	COG1840	ABC-type Fe3 transport system, periplasmic component
HW10_RS17825	COG0456	acetyltransferase
HW10_RS17835	COG0288	reversible hydration of carbon dioxide
HW10_RS17855	COG0012	GTP binding
HW10_RS17910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HW10_RS17930	COG0789	Transcriptional regulator
HW10_RS17940	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HW10_RS17945	COG1090	epimerase
HW10_RS18000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HW10_RS18060	COG1285	pathogenesis
HW10_RS18065	COG2135	peptidase activity
HW10_RS18070	COG0840	transmembrane signaling receptor activity
HW10_RS18075	COG0501	Belongs to the peptidase M48B family
HW10_RS18090	COG2119	membrane
HW10_RS18095	COG0833	amino acid
HW10_RS18105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HW10_RS18140	COG2010	Cytochrome c
HW10_RS18145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HW10_RS18145	COG3608	succinylglutamate desuccinylase aspartoacylase
HW10_RS18215	COG1966	Carbon starvation protein
HW10_RS18220	COG2879	small protein
HW10_RS18225	COG0523	cobalamin synthesis protein
HW10_RS18250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS18255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS18275	COG0488	(ABC) transporter
HW10_RS18280	COG0577	efflux transmembrane transporter activity
HW10_RS18280	COG1136	(ABC) transporter
HW10_RS18285	COG0577	efflux transmembrane transporter activity
HW10_RS18285	COG1136	(ABC) transporter
HW10_RS18310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HW10_RS18330	COG3541	Predicted nucleotidyltransferase
HW10_RS18335	COG1690	Belongs to the RtcB family
HW10_RS18350	COG4650	regulator
HW10_RS18375	COG1067	ATP-dependent peptidase activity
HW10_RS18395	COG0545	Peptidyl-prolyl cis-trans isomerase
HW10_RS18410	COG0142	geranyltranstransferase activity
HW10_RS18435	COG3045	CreA protein
HW10_RS18450	COG0196	riboflavin kinase activity
HW10_RS18465	COG1047	Peptidyl-prolyl cis-trans
HW10_RS18505	COG4969	Belongs to the N-Me-Phe pilin family
HW10_RS18570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HW10_RS18625	COG3609	addiction module antidote protein, CC2985 family
HW10_RS18775	COG2801	Transposase and inactivated derivatives
HW10_RS18780	COG2963	transposase activity
HW10_RS18795	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS18805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS18810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HW10_RS18820	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS18865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HW10_RS18980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW10_RS19005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS19015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HW10_RS19125	COG1192	Involved in chromosome partitioning
HW10_RS19140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW10_RS19145	COG1252	NADH dehydrogenase
HW10_RS19250	COG0019	diaminopimelate decarboxylase activity
HW10_RS19260	COG2194	sulfuric ester hydrolase activity
HW10_RS19275	COG4774	siderophore transport
HW10_RS19280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HW10_RS19300	COG1984	allophanate hydrolase subunit 2
HW10_RS19315	COG4608	Belongs to the ABC transporter superfamily
HW10_RS19320	COG0444	Belongs to the ABC transporter superfamily
HW10_RS19325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HW10_RS19330	COG0601	transmembrane transport
HW10_RS19335	COG0747	negative chemotaxis
HW10_RS19345	COG0747	negative chemotaxis
HW10_RS19360	COG0747	negative chemotaxis
HW10_RS19365	COG0747	negative chemotaxis
HW10_RS19380	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HW10_RS19385	COG4676	Protein conserved in bacteria
HW10_RS19390	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HW10_RS19405	COG5445	Predicted secreted protein (DUF2300)
HW10_RS19410	COG4676	Protein conserved in bacteria
HW10_RS19415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS19420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HW10_RS19440	COG1077	Cell shape determining protein MreB Mrl
HW10_RS19445	COG1792	Involved in formation and maintenance of cell shape
HW10_RS19460	COG1530	ribonuclease E activity
HW10_RS19470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HW10_RS19475	COG0312	modulator of DNA gyrase
HW10_RS19485	COG0312	modulator of DNA gyrase
HW10_RS19540	COG1137	ATPase activity
HW10_RS19555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HW10_RS19565	COG1127	ABC transporter
HW10_RS19570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HW10_RS19575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HW10_RS19615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HW10_RS19625	COG2951	lytic endotransglycosylase activity
HW10_RS19645	COG2945	thiolester hydrolase activity
HW10_RS19655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW10_RS19670	COG1960	acyl-CoA dehydrogenase activity
HW10_RS19675	COG0667	Aldo Keto reductase
HW10_RS19690	COG0723	plastoquinol--plastocyanin reductase activity
HW10_RS19695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HW10_RS19700	COG2857	Cytochrome c1
HW10_RS19705	COG0625	glutathione transferase activity
HW10_RS19710	COG2969	positive regulation of protein catabolic process
HW10_RS19715	COG2823	Periplasmic or secreted lipoprotein
HW10_RS19730	COG3107	peptidoglycan biosynthetic process
HW10_RS19770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HW10_RS19785	COG0772	Belongs to the SEDS family
HW10_RS19830	COG1196	nuclear chromosome segregation
HW10_RS19830	COG0741	lytic transglycosylase activity
HW10_RS19830	COG0739	heme binding
HW10_RS19850	COG0494	nUDIX hydrolase
HW10_RS19855	COG2096	Adenosyltransferase
HW10_RS19870	COG0745	RESPONSE REGULATOR receiver
HW10_RS19880	COG0668	transmembrane transport
HW10_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS19915	COG3030	protein affecting phage T7 exclusion by the F plasmid
HW10_RS19950	COG0745	RESPONSE REGULATOR receiver
HW10_RS19955	COG2205	protein histidine kinase activity
HW10_RS19965	COG3642	lipopolysaccharide core region biosynthetic process
HW10_RS19980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS19985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS20010	COG1704	LemA family
HW10_RS20050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HW10_RS20065	COG1918	ferrous iron import across plasma membrane
HW10_RS20080	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS20085	COG2814	Major facilitator Superfamily
HW10_RS20100	COG0589	response to stress
HW10_RS20120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HW10_RS20120	COG0426	domain, Protein
HW10_RS20125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HW10_RS20140	COG1473	amidohydrolase
HW10_RS20150	COG0154	amidase activity
HW10_RS20165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW10_RS20180	COG0693	protein deglycase activity
HW10_RS20200	COG3706	GGDEF domain
HW10_RS20210	COG1024	Enoyl-CoA hydratase
HW10_RS20220	COG0589	response to stress
HW10_RS20250	COG0714	Associated with various cellular activities
HW10_RS20280	COG2925	Exonuclease
HW10_RS20290	COG0788	formyltetrahydrofolate deformylase activity
HW10_RS20325	COG0433	COG0433 Predicted ATPase
HW10_RS20345	COG4964	Belongs to the GSP D family
HW10_RS20405	COG0306	phosphate transporter
HW10_RS20415	COG0840	transmembrane signaling receptor activity
HW10_RS20430	COG0697	spore germination
HW10_RS20435	COG0095	Lipoate-protein ligase
HW10_RS20440	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HW10_RS20445	COG1074	ATP-dependent DNA helicase activity
HW10_RS20450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HW10_RS20460	COG0420	3'-5' exonuclease activity
HW10_RS20605	COG2831	hemolysin activation secretion protein
HW10_RS20640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS20650	COG0583	DNA-binding transcription factor activity
HW10_RS20670	COG0154	amidase activity
HW10_RS20675	COG0463	Glycosyl transferase, family 2
HW10_RS20690	COG0583	DNA-binding transcription factor activity
HW10_RS20790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HW10_RS20795	COG2910	NAD(P)H-binding
HW10_RS20815	COG1024	Enoyl-CoA hydratase
HW10_RS20820	COG1960	acyl-CoA dehydrogenase activity
HW10_RS20835	COG2720	vancomycin resistance protein
HW10_RS20845	COG3180	Ammonia monooxygenase
HW10_RS20925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HW10_RS20990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HW10_RS21000	COG4206	TonB-dependent receptor
HW10_RS21010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS21015	COG0583	DNA-binding transcription factor activity
HW10_RS21045	COG1113	amino acid transport
HW10_RS21060	COG2079	MmgE PrpD family protein
HW10_RS21075	COG0372	Belongs to the citrate synthase family
HW10_RS21085	COG1802	Transcriptional regulator
HW10_RS21095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS21120	COG0656	L-ascorbic acid biosynthetic process
HW10_RS21135	COG3023	N-Acetylmuramoyl-L-alanine amidase
HW10_RS21150	COG0546	phosphoglycolate phosphatase activity
HW10_RS21165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HW10_RS21200	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HW10_RS21275	COG4735	regulation of single-species biofilm formation
HW10_RS21280	COG4735	regulation of single-species biofilm formation
HW10_RS21325	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HW10_RS21340	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HW10_RS21360	COG1196	nuclear chromosome segregation
HW10_RS21380	COG0515	serine threonine protein kinase
HW10_RS21415	COG2801	Transposase and inactivated derivatives
HW10_RS21420	COG2963	transposase activity
HW10_RS21445	COG2267	carboxylic ester hydrolase activity
HW10_RS21460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS21465	COG2885	chlorophyll binding
HW10_RS21470	COG0204	Acyl-transferase
HW10_RS21490	COG0386	Belongs to the glutathione peroxidase family
HW10_RS21495	COG1309	transcriptional regulator
HW10_RS21505	COG1307	EDD domain protein, DegV family
HW10_RS21540	COG0450	alkyl hydroperoxide reductase
HW10_RS21545	COG0492	ferredoxin-NADP+ reductase activity
HW10_RS21585	COG0271	Belongs to the BolA IbaG family
HW10_RS21605	COG5002	protein histidine kinase activity
HW10_RS21605	COG5001	Diguanylate cyclase
HW10_RS21615	COG0604	alcohol dehydrogenase
HW10_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS21615	COG3321	synthase
HW10_RS21635	COG1113	amino acid transport
HW10_RS21685	COG0583	DNA-binding transcription factor activity
HW10_RS21690	COG0583	DNA-binding transcription factor activity
HW10_RS21695	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HW10_RS21700	COG1960	acyl-CoA dehydrogenase activity
HW10_RS21710	COG2079	MmgE PrpD family protein
HW10_RS21720	COG2301	Belongs to the HpcH HpaI aldolase family
HW10_RS21815	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HW10_RS21885	COG2239	Acts as a magnesium transporter
HW10_RS21895	COG4807	Protein conserved in bacteria
HW10_RS21910	COG3038	cytochrome b561
HW10_RS21960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HW10_RS21965	COG5002	protein histidine kinase activity
HW10_RS21965	COG2205	protein histidine kinase activity
HW10_RS21965	COG0784	Response regulator, receiver
HW10_RS21995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW10_RS22000	COG3956	TIGRFAM MazG family protein
HW10_RS22010	COG3122	Protein conserved in bacteria
HW10_RS22050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HW10_RS22065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HW10_RS22100	COG3118	belongs to the thioredoxin family
HW10_RS22145	COG0783	Belongs to the Dps family
HW10_RS22175	COG0824	Thioesterase
HW10_RS22205	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HW10_RS22210	COG0602	queuosine metabolic process
HW10_RS22225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HW10_RS22235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW10_RS22245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS22250	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW10_RS22260	COG0235	Class ii aldolase
HW10_RS22270	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS22285	COG0475	glutathione-regulated potassium exporter activity
HW10_RS22285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW10_RS22315	COG1051	belongs to the nudix hydrolase family
HW10_RS22335	COG3188	usher protein
HW10_RS22340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW10_RS22395	COG0425	Belongs to the sulfur carrier protein TusA family
HW10_RS22405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HW10_RS22420	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HW10_RS22425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HW10_RS22455	COG0183	Belongs to the thiolase family
HW10_RS22465	COG2030	dehydratase
HW10_RS22470	COG2814	Major facilitator Superfamily
HW10_RS22480	COG1960	acyl-CoA dehydrogenase activity
HW10_RS22485	COG1024	Enoyl-CoA hydratase
HW10_RS22490	COG1960	acyl-CoA dehydrogenase activity
HW10_RS22495	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS22515	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS22520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS22545	COG0625	glutathione transferase activity
HW10_RS22550	COG0653	protein targeting
HW10_RS22565	COG2860	membrane
HW10_RS22605	COG1199	ATP-dependent helicase activity
HW10_RS22620	COG2885	chlorophyll binding
HW10_RS22630	COG3835	regulator
HW10_RS22635	COG2610	gluconate transmembrane transporter activity
HW10_RS22640	COG1929	Belongs to the glycerate kinase type-1 family
HW10_RS22650	COG3133	Outer membrane lipoprotein
HW10_RS22655	COG2111	Na H antiporter
HW10_RS22655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HW10_RS22660	COG1006	Multisubunit Na H antiporter MnhC subunit
HW10_RS22665	COG0651	ATP synthesis coupled electron transport
HW10_RS22670	COG1863	multisubunit Na H antiporter MnhE subunit
HW10_RS22675	COG2212	antiporter activity
HW10_RS22690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HW10_RS22710	COG3189	MarR family transcriptional regulator
HW10_RS22725	COG0326	Molecular chaperone. Has ATPase activity
HW10_RS22770	COG1815	bacterial-type flagellum-dependent cell motility
HW10_RS22780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HW10_RS22790	COG4787	bacterial-type flagellum-dependent cell motility
HW10_RS22850	COG1334	flagellar protein FlaG
HW10_RS22910	COG2882	bacterial-type flagellum organization
HW10_RS22925	COG0477	Major facilitator Superfamily
HW10_RS22930	COG2207	Transcriptional regulator
HW10_RS22945	COG2133	pyrroloquinoline quinone binding
HW10_RS22950	COG4628	conserved protein (DUF2132)
HW10_RS22960	COG1132	(ABC) transporter
HW10_RS22990	COG2885	chlorophyll binding
HW10_RS22995	COG2199	diguanylate cyclase activity
HW10_RS23005	COG0242	peptide deformylase activity
HW10_RS23030	COG0667	Aldo Keto reductase
HW10_RS23035	COG0583	DNA-binding transcription factor activity
HW10_RS23075	COG2197	response regulator
HW10_RS23080	COG3321	synthase
HW10_RS23080	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS23080	COG0604	alcohol dehydrogenase
HW10_RS23095	COG3257	ureidoglycine aminohydrolase activity
HW10_RS23100	COG0583	DNA-binding transcription factor activity
HW10_RS23130	COG0531	amino acid
HW10_RS23170	COG1943	Transposase
HW10_RS23175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW10_RS23180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW10_RS23180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HW10_RS23185	COG0745	RESPONSE REGULATOR receiver
HW10_RS23190	COG2205	protein histidine kinase activity
HW10_RS23205	COG2226	methyltransferase
HW10_RS23220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HW10_RS23225	COG2977	Belongs to the P-Pant transferase superfamily
HW10_RS23250	COG0861	Integral membrane protein TerC family
HW10_RS23255	COG2951	lytic endotransglycosylase activity
HW10_RS23260	COG3005	denitrification pathway
HW10_RS23265	COG3043	anaerobic respiration
HW10_RS23275	COG3062	negative regulation of establishment of protein localization
HW10_RS23280	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW10_RS23280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW10_RS23285	COG4459	periplasmic nitrate reductase
HW10_RS23305	COG5001	Diguanylate cyclase
HW10_RS23305	COG3447	MASE1 domain protein
HW10_RS23305	COG5002	protein histidine kinase activity
HW10_RS23325	COG0625	glutathione transferase activity
HW10_RS23335	COG1960	acyl-CoA dehydrogenase activity
HW10_RS23340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW10_RS23365	COG2818	Glycosylase
HW10_RS23380	COG3829	transcription factor binding
HW10_RS23390	COG0791	NLP P60 protein
HW10_RS23395	COG0791	NLP P60 protein
HW10_RS23405	COG0583	DNA-binding transcription factor activity
HW10_RS23410	COG1335	isochorismatase
HW10_RS23460	COG2211	Major facilitator Superfamily
HW10_RS23470	COG0367	asparagine synthase
HW10_RS23475	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS23485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HW10_RS23510	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HW10_RS23520	COG0583	DNA-binding transcription factor activity
HW10_RS23525	COG2957	Belongs to the agmatine deiminase family
HW10_RS23540	COG2957	Belongs to the agmatine deiminase family
HW10_RS23545	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW10_RS23565	COG2207	Transcriptional regulator
HW10_RS23580	COG1289	transmembrane transporter activity
HW10_RS23620	COG4191	Histidine kinase
HW10_RS23620	COG0784	Response regulator, receiver
HW10_RS23670	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS23675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS23685	COG1126	abc transporter atp-binding protein
HW10_RS23695	COG0765	amino acid transport
HW10_RS23715	COG0477	Major facilitator Superfamily
HW10_RS23745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS23755	COG1802	Transcriptional regulator
HW10_RS23765	COG4206	TonB-dependent receptor
HW10_RS23780	COG0778	Nitroreductase
HW10_RS23810	COG0406	alpha-ribazole phosphatase activity
HW10_RS23830	COG1960	acyl-CoA dehydrogenase activity
HW10_RS23880	COG1450	Type ii and iii secretion system protein
HW10_RS23890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HW10_RS23915	COG0438	transferase activity, transferring glycosyl groups
HW10_RS23920	COG0463	Glycosyl transferase, family 2
HW10_RS23925	COG0438	transferase activity, transferring glycosyl groups
HW10_RS23970	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HW10_RS23995	COG0210	DNA helicase
HW10_RS24005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HW10_RS24005	COG0116	Belongs to the methyltransferase superfamily
HW10_RS24010	COG3264	Mechanosensitive ion channel
HW10_RS24010	COG1196	nuclear chromosome segregation
HW10_RS24020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HW10_RS24035	COG0583	DNA-binding transcription factor activity
HW10_RS24040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS24095	COG0488	(ABC) transporter
HW10_RS24130	COG3300	MHYT domain
HW10_RS24130	COG5001	Diguanylate cyclase
HW10_RS24140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS24145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS24160	COG2832	Protein of unknown function (DUF454)
HW10_RS24200	COG1987	bacterial-type flagellum assembly
HW10_RS24220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HW10_RS24225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HW10_RS24255	COG0784	Response regulator, receiver
HW10_RS24255	COG2198	Histidine kinase
HW10_RS24255	COG0643	Histidine kinase
HW10_RS24265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HW10_RS24270	COG1360	Flagellar Motor Protein
HW10_RS24275	COG1192	Involved in chromosome partitioning
HW10_RS24285	COG0835	chemotaxis
HW10_RS24315	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS24330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HW10_RS24405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HW10_RS24410	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS24425	COG3192	ethanolamine utilization protein
HW10_RS24435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HW10_RS24450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HW10_RS24455	COG4413	Urea transporter
HW10_RS24460	COG0469	pyruvate kinase activity
HW10_RS24470	COG2084	Dehydrogenase
HW10_RS24475	COG3622	Belongs to the hyi family
HW10_RS24480	COG3960	tartronate-semialdehyde synthase activity
HW10_RS24490	COG1309	transcriptional regulator
HW10_RS24505	COG2233	PERMEase
HW10_RS24565	COG2252	PERMEase
HW10_RS24595	COG1230	cation diffusion facilitator family transporter
HW10_RS24610	COG1595	DNA-templated transcription, initiation
HW10_RS24615	COG3712	iron ion homeostasis
HW10_RS24645	COG0121	glutamine amidotransferase
HW10_RS24655	COG0583	DNA-binding transcription factor activity
HW10_RS24675	COG2814	Major facilitator Superfamily
HW10_RS24720	COG4774	siderophore transport
HW10_RS24735	COG4319	ketosteroid isomerase
HW10_RS24740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HW10_RS24745	COG1864	DNA RNA non-specific endonuclease
HW10_RS24745	COG3591	Belongs to the peptidase S1B family
HW10_RS24750	COG0583	DNA-binding transcription factor activity
HW10_RS24760	COG0300	oxidoreductase activity
HW10_RS24765	COG1253	flavin adenine dinucleotide binding
HW10_RS24780	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS24805	COG1126	abc transporter atp-binding protein
HW10_RS24810	COG0765	amino acid transport
HW10_RS24815	COG0765	amino acid transport
HW10_RS24830	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS24835	COG0189	ligase activity
HW10_RS24840	COG1982	Orn Lys Arg decarboxylase major
HW10_RS24845	COG2197	response regulator
HW10_RS24855	COG3795	YCII-related domain
HW10_RS24865	COG4941	Belongs to the sigma-70 factor family
HW10_RS24870	COG2814	Major facilitator Superfamily
HW10_RS24880	COG3795	YCII-related domain
HW10_RS24895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HW10_RS24910	COG5006	permease, DMT superfamily
HW10_RS24940	COG0384	phenazine biosynthesis protein PhzF
HW10_RS24945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HW10_RS24985	COG1247	-acetyltransferase
HW10_RS24990	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS25020	COG1196	nuclear chromosome segregation
HW10_RS25055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HW10_RS25070	COG1960	acyl-CoA dehydrogenase activity
HW10_RS25100	COG2076	Multidrug Resistance protein
HW10_RS25140	COG2217	Heavy metal translocating P-type atpase
HW10_RS25150	COG0348	domain, Protein
HW10_RS25155	COG2010	Cytochrome c
HW10_RS25170	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS25175	COG2010	Cytochrome c
HW10_RS25190	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS25205	COG0840	transmembrane signaling receptor activity
HW10_RS25225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS25230	COG0174	glutamine synthetase
HW10_RS25235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS25240	COG0251	oxidation-reduction process
HW10_RS25265	COG3738	Protein conserved in bacteria
HW10_RS25280	COG2084	Dehydrogenase
HW10_RS25310	COG2009	succinate dehydrogenase
HW10_RS25315	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HW10_RS25320	COG1053	succinate dehydrogenase
HW10_RS25325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HW10_RS25400	COG2207	Transcriptional regulator
HW10_RS25405	COG2010	Cytochrome c
HW10_RS25405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HW10_RS25410	COG2010	Cytochrome c
HW10_RS25410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HW10_RS25415	COG2080	2 iron, 2 sulfur cluster binding
HW10_RS25420	COG1846	Transcriptional regulator
HW10_RS25460	COG0784	Response regulator, receiver
HW10_RS25460	COG5002	protein histidine kinase activity
HW10_RS25460	COG2205	protein histidine kinase activity
HW10_RS25490	COG1022	Amp-dependent synthetase and ligase
HW10_RS25520	COG0625	glutathione transferase activity
HW10_RS25530	COG0628	permease
HW10_RS25535	COG2807	transmembrane transport
HW10_RS25540	COG2186	Transcriptional regulator
HW10_RS25545	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS25550	COG1024	Enoyl-CoA hydratase
HW10_RS25560	COG1960	acyl-CoA dehydrogenase activity
HW10_RS25585	COG2205	protein histidine kinase activity
HW10_RS25590	COG0745	RESPONSE REGULATOR receiver
HW10_RS25630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HW10_RS25640	COG0840	transmembrane signaling receptor activity
HW10_RS25650	COG2130	NADP-dependent
HW10_RS25655	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS25665	COG3135	benzoate transporter
HW10_RS25680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS25685	COG0625	glutathione transferase activity
HW10_RS25725	COG2204	response regulator
HW10_RS25765	COG2815	serine threonine protein kinase
HW10_RS25765	COG0515	serine threonine protein kinase
HW10_RS25785	COG2840	Smr protein MutS2
HW10_RS25865	COG4792	protein secretion
HW10_RS25870	COG4791	protein targeting
HW10_RS25875	COG4794	Type iii secretion
HW10_RS25880	COG4790	Type iii secretion
HW10_RS25930	COG4789	Type iii secretion
HW10_RS26040	COG1317	bacterial-type flagellum organization
HW10_RS26060	COG0505	Belongs to the CarA family
HW10_RS26065	COG2308	Evidence 4 Homologs of previously reported genes of
HW10_RS26075	COG1305	Transglutaminase-like
HW10_RS26095	COG0183	Belongs to the thiolase family
HW10_RS26100	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS26100	COG1024	Enoyl-CoA hydratase
HW10_RS26110	COG0667	Aldo Keto reductase
HW10_RS26125	COG0519	Catalyzes the synthesis of GMP from XMP
HW10_RS26180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HW10_RS26215	COG2909	trisaccharide binding
HW10_RS26220	COG2909	trisaccharide binding
HW10_RS26260	COG0189	ligase activity
HW10_RS26260	COG4067	protein conserved in archaea
HW10_RS26300	COG0668	transmembrane transport
HW10_RS26320	COG0243	molybdopterin cofactor binding
HW10_RS26325	COG2146	nitrite reductase [NAD(P)H] activity
HW10_RS26330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS26335	COG0515	serine threonine protein kinase
HW10_RS26340	COG2223	nitrite transmembrane transporter activity
HW10_RS26350	COG2201	protein-glutamate methylesterase activity
HW10_RS26370	COG0589	response to stress
HW10_RS26390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HW10_RS26435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HW10_RS26440	COG2205	protein histidine kinase activity
HW10_RS26445	COG0745	RESPONSE REGULATOR receiver
HW10_RS26465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HW10_RS26480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS26490	COG4172	Belongs to the ABC transporter superfamily
HW10_RS26495	COG4239	(ABC) transporter, permease
HW10_RS26500	COG4174	ABC transporter (Permease)
HW10_RS26505	COG4166	transmembrane transport
HW10_RS26510	COG4166	transmembrane transport
HW10_RS26515	COG1388	LysM domain
HW10_RS26515	COG0741	lytic transglycosylase activity
HW10_RS26535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HW10_RS26550	COG0531	amino acid
HW10_RS26560	COG1024	Enoyl-CoA hydratase
HW10_RS26585	COG0583	DNA-binding transcription factor activity
HW10_RS26590	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS26595	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS26615	COG0616	signal peptide processing
HW10_RS26620	COG0604	alcohol dehydrogenase
HW10_RS26645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS26710	COG3813	Protein conserved in bacteria
HW10_RS26715	COG4977	sequence-specific DNA binding
HW10_RS26720	COG2203	Gaf domain
HW10_RS26720	COG5001	Diguanylate cyclase
HW10_RS26720	COG4251	negative regulation of phosphorylation
HW10_RS26720	COG3706	GGDEF domain
HW10_RS26735	COG2239	Acts as a magnesium transporter
HW10_RS26745	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS26750	COG2354	Protein conserved in bacteria
HW10_RS26760	COG0583	DNA-binding transcription factor activity
HW10_RS26765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HW10_RS26785	COG1309	transcriptional regulator
HW10_RS26855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS26900	COG0417	DNA replication proofreading
HW10_RS26905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS26920	COG0625	glutathione transferase activity
HW10_RS26935	COG2366	antibiotic biosynthetic process
HW10_RS26960	COG2197	response regulator
HW10_RS27010	COG2814	Major facilitator Superfamily
HW10_RS27030	COG3712	iron ion homeostasis
HW10_RS27035	COG1595	DNA-templated transcription, initiation
HW10_RS27065	COG0579	oxidoreductase
HW10_RS27080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW10_RS27080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HW10_RS27085	COG0275	rRNA processing
HW10_RS27090	COG4771	TonB-dependent receptor
HW10_RS27110	COG1944	ATP diphosphatase activity
HW10_RS27155	COG0753	catalase activity
HW10_RS27160	COG2010	Cytochrome c
HW10_RS27175	COG2204	response regulator
HW10_RS27185	COG1129	ABC transporter
HW10_RS27190	COG1172	Belongs to the binding-protein-dependent transport system permease family
HW10_RS27195	COG1609	Transcriptional regulator
HW10_RS27200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW10_RS27250	COG1278	Cold shock
HW10_RS27255	COG0583	DNA-binding transcription factor activity
HW10_RS27270	COG0488	(ABC) transporter
HW10_RS27315	COG2194	sulfuric ester hydrolase activity
HW10_RS27335	COG0784	Response regulator, receiver
HW10_RS27335	COG2205	protein histidine kinase activity
HW10_RS27350	COG3851	Histidine kinase
HW10_RS27415	COG2205	protein histidine kinase activity
HW10_RS27435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS27440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HW10_RS27445	COG0583	DNA-binding transcription factor activity
HW10_RS27450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HW10_RS27465	COG2031	fatty acid transporter
HW10_RS27470	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS27475	COG2610	gluconate transmembrane transporter activity
HW10_RS27480	COG3829	transcription factor binding
HW10_RS27480	COG3290	protein histidine kinase activity
HW10_RS27485	COG2271	Major facilitator Superfamily
HW10_RS27495	COG0179	Fumarylacetoacetate (FAA) hydrolase
HW10_RS27525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HW10_RS27530	COG1960	acyl-CoA dehydrogenase activity
HW10_RS27535	COG0789	Transcriptional regulator
HW10_RS27540	COG3204	pilus organization
HW10_RS27550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS27555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS27560	COG1309	transcriptional regulator
HW10_RS27600	COG1522	sequence-specific DNA binding
HW10_RS27620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS27635	COG0028	Belongs to the TPP enzyme family
HW10_RS27650	COG0174	glutamine synthetase
HW10_RS27655	COG0531	amino acid
HW10_RS27665	COG0564	pseudouridine synthase activity
HW10_RS27685	COG2207	Transcriptional regulator
HW10_RS27700	COG1595	DNA-templated transcription, initiation
HW10_RS27720	COG0583	DNA-binding transcription factor activity
HW10_RS27735	COG4771	TonB-dependent receptor
HW10_RS27745	COG4174	ABC transporter (Permease)
HW10_RS27750	COG4239	(ABC) transporter, permease
HW10_RS27755	COG4172	Belongs to the ABC transporter superfamily
HW10_RS27760	COG1104	cysteine desulfurase activity
HW10_RS27790	COG2814	Major facilitator Superfamily
HW10_RS27795	COG2192	nodulation
HW10_RS27800	COG4206	TonB-dependent receptor
HW10_RS27810	COG5001	Diguanylate cyclase
HW10_RS27830	COG2010	Cytochrome c
HW10_RS27835	COG2010	Cytochrome c
HW10_RS27840	COG1113	amino acid transport
HW10_RS27855	COG1522	sequence-specific DNA binding
HW10_RS27865	COG0367	asparagine synthase
HW10_RS27870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HW10_RS27875	COG0596	Alpha beta hydrolase
HW10_RS27895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS27905	COG2814	Major facilitator Superfamily
HW10_RS27940	COG0300	oxidoreductase activity
HW10_RS27945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS27965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HW10_RS27970	COG1045	serine acetyltransferase
HW10_RS27975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HW10_RS27985	COG0028	Belongs to the TPP enzyme family
HW10_RS27995	COG1984	allophanate hydrolase subunit 2
HW10_RS28015	COG2814	Major facilitator Superfamily
HW10_RS28020	COG0583	DNA-binding transcription factor activity
HW10_RS28035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW10_RS28035	COG2169	Transcriptional regulator
HW10_RS28045	COG1063	alcohol dehydrogenase
HW10_RS28065	COG0583	DNA-binding transcription factor activity
HW10_RS28070	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW10_RS28075	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS28080	COG1475	DNA binding
HW10_RS28090	COG3969	phosphoadenosine phosphosulfate
HW10_RS28100	COG3121	Chaperone
HW10_RS28105	COG3188	usher protein
HW10_RS28115	COG3121	Chaperone
HW10_RS28135	COG2323	membrane
HW10_RS28165	COG1546	Belongs to the CinA family
HW10_RS28170	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS28185	COG0058	SHG alpha-glucan phosphorylase activity
HW10_RS28205	COG1285	pathogenesis
HW10_RS28225	COG0366	Alpha amylase catalytic
HW10_RS28235	COG0392	lysyltransferase activity
HW10_RS28240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW10_RS28245	COG3568	Endonuclease Exonuclease Phosphatase
HW10_RS28285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HW10_RS28325	COG1363	Peptidase, m42
HW10_RS28355	COG0784	Response regulator, receiver
HW10_RS28355	COG4191	Histidine kinase
HW10_RS28370	COG2890	protein-(glutamine-N5) methyltransferase activity
HW10_RS28400	COG0517	IMP dehydrogenase activity
HW10_RS28405	COG0366	Alpha amylase catalytic
HW10_RS28425	COG1309	transcriptional regulator
HW10_RS28430	COG2130	NADP-dependent
HW10_RS28440	COG2084	Dehydrogenase
HW10_RS28455	COG0765	amino acid transport
HW10_RS28460	COG0765	amino acid transport
HW10_RS28495	COG2271	Major facilitator Superfamily
HW10_RS28500	COG3618	amidohydrolase
HW10_RS28515	COG2271	Major facilitator Superfamily
HW10_RS28520	COG4948	Mandelate Racemase Muconate Lactonizing
HW10_RS28530	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS28535	COG2995	paraquat-inducible protein a
HW10_RS28540	COG3008	intermembrane lipid transfer
HW10_RS28570	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS28575	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS28580	COG3162	membrane
HW10_RS28585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS28600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HW10_RS28605	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS28610	COG0531	amino acid
HW10_RS28625	COG2072	flavoprotein involved in K transport
HW10_RS28640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS28660	COG2409	Drug exporters of the RND superfamily
HW10_RS28665	COG4447	cellulose binding
HW10_RS28675	COG2508	Transcriptional regulator
HW10_RS28685	COG2963	transposase activity
HW10_RS28710	COG2801	Transposase and inactivated derivatives
HW10_RS28750	COG2258	MOSC domain
HW10_RS28810	COG0728	peptidoglycan biosynthetic process
HW10_RS28820	COG1053	succinate dehydrogenase
HW10_RS28865	COG1115	amino acid carrier protein
HW10_RS28870	COG0252	asparaginase activity
HW10_RS28900	COG1609	Transcriptional regulator
HW10_RS28910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW10_RS28945	COG2329	Antibiotic biosynthesis monooxygenase
HW10_RS28955	COG1309	transcriptional regulator
HW10_RS28980	COG1064	alcohol dehydrogenase
HW10_RS28985	COG2207	Transcriptional regulator
HW10_RS28990	COG0640	Transcriptional regulator
HW10_RS29000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HW10_RS29005	COG0431	NADPH-dependent FMN reductase
HW10_RS29050	COG4772	TonB-dependent receptor
HW10_RS29080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS29095	COG1053	succinate dehydrogenase
HW10_RS29100	COG2188	Transcriptional regulator
HW10_RS29105	COG3469	chitinase activity
HW10_RS29115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS29115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS29140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS29145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HW10_RS29155	COG2175	clavaminate synthase activity
HW10_RS29165	COG1396	sequence-specific DNA binding
HW10_RS29185	COG0583	DNA-binding transcription factor activity
HW10_RS29190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS29200	COG1609	Transcriptional regulator
HW10_RS29205	COG3265	gluconokinase activity
HW10_RS29215	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS29235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS29240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS29245	COG1116	anion transmembrane transporter activity
HW10_RS29260	COG4977	sequence-specific DNA binding
HW10_RS29260	COG1917	Cupin 2, conserved barrel domain protein
HW10_RS29275	COG4771	TonB-dependent receptor
HW10_RS29295	COG1175	transmembrane transport
HW10_RS29310	COG0246	Mannitol dehydrogenase
HW10_RS29315	COG1070	Carbohydrate kinase
HW10_RS29320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW10_RS29345	COG1464	Belongs to the NlpA lipoprotein family
HW10_RS29355	COG2011	ABC-type metal ion transport system permease component
HW10_RS29360	COG0584	glycerophosphoryl diester phosphodiesterase
HW10_RS29365	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW10_RS29370	COG3829	transcription factor binding
HW10_RS29395	COG3829	transcription factor binding
HW10_RS29485	COG4566	intracellular signal transduction
HW10_RS29515	COG1304	FMN binding
HW10_RS29525	COG0735	belongs to the Fur family
HW10_RS29550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS29645	COG1121	(ABC) transporter
HW10_RS29650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HW10_RS29690	COG0583	DNA-binding transcription factor activity
HW10_RS29700	COG1335	isochorismatase