locus-tag	class	description
HW10_RS00035	COG2010	Cytochrome c
HW10_RS00050	COG2818	Glycosylase
HW10_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HW10_RS00080	COG0569	domain protein
HW10_RS00100	COG1652	LysM domain
HW10_RS00105	COG0758	DNA mediated transformation
HW10_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS00155	COG3119	arylsulfatase activity
HW10_RS00160	COG0583	DNA-binding transcription factor activity
HW10_RS00195	COG3360	Dodecin
HW10_RS00270	COG3174	membrane
HW10_RS00315	COG0367	asparagine synthase
HW10_RS00340	COG0583	DNA-binding transcription factor activity
HW10_RS00355	COG1764	response to oxidative stress
HW10_RS00390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HW10_RS00395	COG0339	signal peptide processing
HW10_RS00400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HW10_RS00415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HW10_RS00430	COG0515	serine threonine protein kinase
HW10_RS00430	COG2815	serine threonine protein kinase
HW10_RS00435	COG0631	protein serine/threonine phosphatase activity
HW10_RS00450	COG1360	Flagellar Motor Protein
HW10_RS00575	COG0659	secondary active sulfate transmembrane transporter activity
HW10_RS00590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HW10_RS00595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HW10_RS00600	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HW10_RS00640	COG2153	protein acetylation
HW10_RS00680	COG0583	DNA-binding transcription factor activity
HW10_RS00705	COG2824	Alkylphosphonate utilization operon protein PhnA
HW10_RS00735	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS00745	COG3845	ABC transporter
HW10_RS00750	COG4603	Belongs to the binding-protein-dependent transport system permease family
HW10_RS00755	COG1079	Belongs to the binding-protein-dependent transport system permease family
HW10_RS00830	COG0583	DNA-binding transcription factor activity
HW10_RS00835	COG3485	protocatechuate 3,4-dioxygenase
HW10_RS00840	COG3485	protocatechuate 3,4-dioxygenase
HW10_RS00850	COG1414	Transcriptional regulator
HW10_RS00865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS00870	COG0583	DNA-binding transcription factor activity
HW10_RS00905	COG2233	PERMEase
HW10_RS00910	COG1309	transcriptional regulator
HW10_RS00945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HW10_RS00960	COG0835	chemotaxis
HW10_RS00965	COG0643	Histidine kinase
HW10_RS00965	COG2198	Histidine kinase
HW10_RS00970	COG0745	RESPONSE REGULATOR receiver
HW10_RS00980	COG0583	DNA-binding transcription factor activity
HW10_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS00995	COG1116	anion transmembrane transporter activity
HW10_RS01000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS01005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS01050	COG2175	clavaminate synthase activity
HW10_RS01125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HW10_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS01165	COG1113	amino acid transport
HW10_RS01180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS01185	COG0235	Class ii aldolase
HW10_RS01190	COG1396	sequence-specific DNA binding
HW10_RS01195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HW10_RS01200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HW10_RS01210	COG0477	Major facilitator Superfamily
HW10_RS01220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS01225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS01230	COG0583	DNA-binding transcription factor activity
HW10_RS01250	COG0673	inositol 2-dehydrogenase activity
HW10_RS01270	COG2271	Major facilitator Superfamily
HW10_RS01280	COG1309	transcriptional regulator
HW10_RS01285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HW10_RS01295	COG0477	Major facilitator Superfamily
HW10_RS01315	COG2239	Acts as a magnesium transporter
HW10_RS01445	COG0745	RESPONSE REGULATOR receiver
HW10_RS01455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS01470	COG0583	DNA-binding transcription factor activity
HW10_RS01475	COG2807	transmembrane transport
HW10_RS01495	COG0501	Belongs to the peptidase M48B family
HW10_RS01515	COG4208	sulfate ABC transporter
HW10_RS01525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HW10_RS01545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS01560	COG2199	diguanylate cyclase activity
HW10_RS01585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HW10_RS01590	COG0174	glutamine synthetase
HW10_RS01595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HW10_RS01600	COG0174	glutamine synthetase
HW10_RS01620	COG3842	ATPase activity
HW10_RS01625	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS01630	COG1177	transmembrane transport
HW10_RS01685	COG0765	amino acid transport
HW10_RS01700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HW10_RS01705	COG0277	FAD linked oxidase domain protein
HW10_RS01710	COG0179	Fumarylacetoacetate (FAA) hydrolase
HW10_RS01720	COG3111	PFAM Bacterial OB fold (BOF) protein
HW10_RS01730	COG0531	amino acid
HW10_RS01735	COG2182	Extracellular solute-binding protein
HW10_RS01740	COG1177	transmembrane transport
HW10_RS01750	COG3842	ATPase activity
HW10_RS01760	COG3204	pilus organization
HW10_RS01765	COG2234	aminopeptidase activity
HW10_RS01785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HW10_RS01795	COG0702	epimerase
HW10_RS01835	COG0730	response to heat
HW10_RS01870	COG0584	glycerophosphoryl diester phosphodiesterase
HW10_RS01890	COG0622	Phosphoesterase
HW10_RS01895	COG2233	PERMEase
HW10_RS01910	COG0693	protein deglycase activity
HW10_RS01945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW10_RS01955	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW10_RS01980	COG0429	hydrolase of the alpha beta-hydrolase fold
HW10_RS01990	COG0742	ribosomal rna small subunit methyltransferase
HW10_RS01995	COG0612	Peptidase, M16
HW10_RS02000	COG0612	Peptidase, M16
HW10_RS02005	COG0552	protein localization to endoplasmic reticulum
HW10_RS02010	COG2884	Cell division ATP-binding protein ftsE
HW10_RS02015	COG2177	Part of the ABC transporter FtsEX involved in
HW10_RS02035	COG2363	Small membrane protein
HW10_RS02070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HW10_RS02085	COG2813	Specifically methylates the guanine in position
HW10_RS02085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS02095	COG1160	GTP binding
HW10_RS02100	COG1872	DUF167
HW10_RS02145	COG0626	cystathionine gamma-synthase activity
HW10_RS02210	COG0784	Response regulator, receiver
HW10_RS02210	COG0643	Histidine kinase
HW10_RS02210	COG2198	Histidine kinase
HW10_RS02240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HW10_RS02260	COG3038	cytochrome b561
HW10_RS02290	COG0513	Belongs to the DEAD box helicase family
HW10_RS02300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HW10_RS02305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW10_RS02330	COG1309	transcriptional regulator
HW10_RS02335	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS02340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HW10_RS02375	COG1953	Uracil, thiamine, allantoin
HW10_RS02390	COG1960	acyl-CoA dehydrogenase activity
HW10_RS02395	COG0583	DNA-binding transcription factor activity
HW10_RS02415	COG0330	HflC and HflK could
HW10_RS02425	COG1289	transmembrane transporter activity
HW10_RS02430	COG0513	Belongs to the DEAD box helicase family
HW10_RS02440	COG4067	protein conserved in archaea
HW10_RS02440	COG0189	ligase activity
HW10_RS02450	COG0477	Major facilitator Superfamily
HW10_RS02460	COG0542	response to heat
HW10_RS02470	COG0204	Acyl-transferase
HW10_RS02480	COG0745	RESPONSE REGULATOR receiver
HW10_RS02485	COG2205	protein histidine kinase activity
HW10_RS02490	COG4452	Inner membrane protein CreD
HW10_RS02525	COG4774	siderophore transport
HW10_RS02530	COG3712	iron ion homeostasis
HW10_RS02535	COG1595	DNA-templated transcription, initiation
HW10_RS02540	COG0625	glutathione transferase activity
HW10_RS02550	COG1309	transcriptional regulator
HW10_RS02555	COG1953	Uracil, thiamine, allantoin
HW10_RS02575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS02610	COG3585	molybdate ion transport
HW10_RS02610	COG2005	Transcriptional regulator
HW10_RS02615	COG5544	Lipoprotein
HW10_RS02620	COG1040	competence protein
HW10_RS02640	COG0511	ligase activity, forming carbon-carbon bonds
HW10_RS02655	COG1984	allophanate hydrolase subunit 2
HW10_RS02665	COG3121	Chaperone
HW10_RS02680	COG2226	methyltransferase
HW10_RS02680	COG1073	alpha beta
HW10_RS02700	COG1960	acyl-CoA dehydrogenase activity
HW10_RS02705	COG1960	acyl-CoA dehydrogenase activity
HW10_RS02715	COG1960	acyl-CoA dehydrogenase activity
HW10_RS02725	COG1648	precorrin-2 dehydrogenase activity
HW10_RS02725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HW10_RS02810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HW10_RS02815	COG0583	DNA-binding transcription factor activity
HW10_RS02820	COG2258	MOSC domain
HW10_RS02830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HW10_RS02855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS02865	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HW10_RS02920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS02925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HW10_RS02935	COG3622	Belongs to the hyi family
HW10_RS02940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HW10_RS02980	COG2081	HI0933 family
HW10_RS02985	COG1451	nucleotide metabolic process
HW10_RS02995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HW10_RS03000	COG3152	Membrane
HW10_RS03005	COG4977	sequence-specific DNA binding
HW10_RS03005	COG1917	Cupin 2, conserved barrel domain protein
HW10_RS03010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS03110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HW10_RS03130	COG2719	SpoVR family
HW10_RS03140	COG2766	serine protein kinase
HW10_RS03190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HW10_RS03205	COG2197	response regulator
HW10_RS03215	COG3842	ATPase activity
HW10_RS03225	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS03235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HW10_RS03260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW10_RS03345	COG3179	chitinase
HW10_RS03380	COG1765	OsmC-like protein
HW10_RS03395	COG0537	adenosine 5'-monophosphoramidase activity
HW10_RS03405	COG0300	oxidoreductase activity
HW10_RS03420	COG1981	membrane
HW10_RS03450	COG0739	heme binding
HW10_RS03615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HW10_RS03740	COG2814	Major facilitator Superfamily
HW10_RS03765	COG1021	2,3-dihydroxybenzoate-AMP ligase
HW10_RS03775	COG3433	isochorismatase activity
HW10_RS03775	COG2226	methyltransferase
HW10_RS03775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS03780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS03780	COG2226	methyltransferase
HW10_RS03780	COG3433	isochorismatase activity
HW10_RS03790	COG2375	cellular response to nickel ion
HW10_RS03790	COG1132	(ABC) transporter
HW10_RS03875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS03880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS03890	COG2706	6-phosphogluconolactonase activity
HW10_RS03910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS03915	COG1960	acyl-CoA dehydrogenase activity
HW10_RS03925	COG4191	Histidine kinase
HW10_RS03930	COG4566	intracellular signal transduction
HW10_RS03935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS03940	COG0765	amino acid transport
HW10_RS03945	COG0765	amino acid transport
HW10_RS03965	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS03970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS03975	COG2271	Major facilitator Superfamily
HW10_RS04025	COG2226	methyltransferase
HW10_RS04035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS04050	COG0251	oxidation-reduction process
HW10_RS04060	COG0693	protein deglycase activity
HW10_RS04065	COG0492	ferredoxin-NADP+ reductase activity
HW10_RS04070	COG1959	2 iron, 2 sulfur cluster binding
HW10_RS04100	COG0154	amidase activity
HW10_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS04115	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS04120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS04125	COG4592	Periplasmic binding protein
HW10_RS04130	COG1120	ATPase activity
HW10_RS04140	COG1629	transport
HW10_RS04140	COG4774	siderophore transport
HW10_RS04145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS04150	COG4991	sh3 domain protein
HW10_RS04155	COG1063	alcohol dehydrogenase
HW10_RS04165	COG0022	dehydrogenase e1 component
HW10_RS04170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HW10_RS04175	COG3199	ATP-NAD kinase
HW10_RS04185	COG3284	Transcriptional regulator
HW10_RS04210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS04245	COG2814	Major facilitator Superfamily
HW10_RS04250	COG1846	Transcriptional regulator
HW10_RS04260	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS04265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS04275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS04290	COG3971	2-oxopent-4-enoate hydratase activity
HW10_RS04295	COG2271	Major facilitator Superfamily
HW10_RS04305	COG3384	dioxygenase
HW10_RS04310	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS04350	COG1611	Belongs to the LOG family
HW10_RS04410	COG2259	Doxx family
HW10_RS04420	COG2205	protein histidine kinase activity
HW10_RS04445	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS04450	COG1063	alcohol dehydrogenase
HW10_RS04455	COG2271	Major facilitator Superfamily
HW10_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS04495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HW10_RS04510	COG3121	Chaperone
HW10_RS04515	COG3188	usher protein
HW10_RS04520	COG3121	Chaperone
HW10_RS04525	COG3210	domain, Protein
HW10_RS04535	COG2197	response regulator
HW10_RS04575	COG0531	amino acid
HW10_RS04595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HW10_RS04605	COG3047	cAMP biosynthetic process
HW10_RS04635	COG3118	belongs to the thioredoxin family
HW10_RS04640	COG2264	protein methyltransferase activity
HW10_RS04660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HW10_RS04660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HW10_RS04685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HW10_RS04690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HW10_RS04700	COG3577	Aspartyl protease
HW10_RS04725	COG0142	geranyltranstransferase activity
HW10_RS04735	COG4948	Mandelate Racemase Muconate Lactonizing
HW10_RS04755	COG1131	(ABC) transporter
HW10_RS04760	COG5002	protein histidine kinase activity
HW10_RS04780	COG0745	RESPONSE REGULATOR receiver
HW10_RS04790	COG3228	Belongs to the MtfA family
HW10_RS04795	COG0586	Pfam SNARE associated Golgi protein
HW10_RS04810	COG0456	acetyltransferase
HW10_RS04820	COG4303	Ethanolamine ammonia lyase large subunit
HW10_RS04825	COG0531	amino acid
HW10_RS04835	COG3284	Transcriptional regulator
HW10_RS04840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HW10_RS04855	COG0702	epimerase
HW10_RS04875	COG1346	cytolysis
HW10_RS04885	COG0586	Pfam SNARE associated Golgi protein
HW10_RS04925	COG0768	penicillin binding
HW10_RS04930	COG0772	Belongs to the SEDS family
HW10_RS04935	COG2951	lytic endotransglycosylase activity
HW10_RS04945	COG1686	Belongs to the peptidase S11 family
HW10_RS04975	COG2951	lytic endotransglycosylase activity
HW10_RS05010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HW10_RS05020	COG4535	Mg2 and Co2 transporter CorC
HW10_RS05030	COG1702	phosphate starvation-inducible protein PhoH
HW10_RS05060	COG0351	phosphomethylpyrimidine kinase
HW10_RS05065	COG2198	Histidine kinase
HW10_RS05065	COG0784	Response regulator, receiver
HW10_RS05065	COG2205	protein histidine kinase activity
HW10_RS05075	COG1960	acyl-CoA dehydrogenase activity
HW10_RS05085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HW10_RS05125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HW10_RS05135	COG1643	Atp-dependent helicase
HW10_RS05170	COG1061	Type III restriction enzyme res subunit
HW10_RS05195	COG1074	ATP-dependent DNA helicase activity
HW10_RS05200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS05245	COG0300	oxidoreductase activity
HW10_RS05270	COG3416	Protein conserved in bacteria
HW10_RS05280	COG0513	Belongs to the DEAD box helicase family
HW10_RS05295	COG2197	response regulator
HW10_RS05300	COG2200	EAL domain
HW10_RS05300	COG2202	Pas domain
HW10_RS05300	COG2199	diguanylate cyclase activity
HW10_RS05305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS05305	COG2205	protein histidine kinase activity
HW10_RS05325	COG1946	Acyl-CoA thioesterase
HW10_RS05345	COG4521	taurine ABC transporter
HW10_RS05355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS05360	COG2175	clavaminate synthase activity
HW10_RS05365	COG1297	OPT oligopeptide transporter protein
HW10_RS05370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW10_RS05385	COG1271	oxidase subunit
HW10_RS05390	COG1294	oxidase, subunit
HW10_RS05400	COG2207	Transcriptional regulator
HW10_RS05410	COG0183	Belongs to the thiolase family
HW10_RS05415	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS05450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HW10_RS05460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HW10_RS05470	COG0521	Mo-molybdopterin cofactor biosynthetic process
HW10_RS05475	COG0303	'Molybdopterin
HW10_RS05480	COG0826	peptidase U32
HW10_RS05485	COG0826	peptidase U32
HW10_RS05490	COG3154	lipid carrier protein
HW10_RS05540	COG4772	TonB-dependent receptor
HW10_RS05545	COG3712	iron ion homeostasis
HW10_RS05550	COG1595	DNA-templated transcription, initiation
HW10_RS05560	COG0697	spore germination
HW10_RS05570	COG0583	DNA-binding transcription factor activity
HW10_RS05590	COG1566	PFAM secretion protein HlyD family protein
HW10_RS05645	COG0300	oxidoreductase activity
HW10_RS05650	COG2226	methyltransferase
HW10_RS05665	COG2197	response regulator
HW10_RS05670	COG3850	Histidine kinase
HW10_RS05680	COG2223	nitrite transmembrane transporter activity
HW10_RS05685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HW10_RS05690	COG1140	nitrate reductase beta subunit
HW10_RS05695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HW10_RS05700	COG2181	nitrate reductase activity
HW10_RS05705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS05745	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS05755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS05820	COG0583	DNA-binding transcription factor activity
HW10_RS05855	COG0490	domain, Protein
HW10_RS05855	COG0471	metal ion transport
HW10_RS05860	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HW10_RS05865	COG4120	Belongs to the binding-protein-dependent transport system permease family
HW10_RS05910	COG0795	lipopolysaccharide-transporting ATPase activity
HW10_RS05915	COG0795	lipopolysaccharide-transporting ATPase activity
HW10_RS05925	COG2200	EAL domain
HW10_RS05955	COG1862	Preprotein translocase
HW10_RS05970	COG3134	Outer membrane lipoprotein
HW10_RS05985	COG1045	serine acetyltransferase
HW10_RS06075	COG0436	Aminotransferase
HW10_RS06090	COG0667	Aldo Keto reductase
HW10_RS06130	COG0739	heme binding
HW10_RS06140	COG2847	Copper chaperone PCu(A)C
HW10_RS06150	COG1335	isochorismatase
HW10_RS06165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HW10_RS06175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HW10_RS06180	COG0583	DNA-binding transcription factor activity
HW10_RS06230	COG2132	Multicopper oxidase
HW10_RS06235	COG0590	tRNA wobble adenosine to inosine editing
HW10_RS06280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HW10_RS06280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HW10_RS06285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HW10_RS06290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HW10_RS06295	COG2188	Transcriptional regulator
HW10_RS06335	COG0477	Major facilitator Superfamily
HW10_RS06340	COG4536	flavin adenine dinucleotide binding
HW10_RS06350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HW10_RS06375	COG1607	acyl-coa hydrolase
HW10_RS06395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HW10_RS06420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW10_RS06460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HW10_RS06470	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS06515	COG2197	response regulator
HW10_RS06520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HW10_RS06540	COG0477	Major facilitator Superfamily
HW10_RS06575	COG4251	negative regulation of phosphorylation
HW10_RS06575	COG5001	Diguanylate cyclase
HW10_RS06575	COG3706	GGDEF domain
HW10_RS06575	COG2203	Gaf domain
HW10_RS06610	COG3064	Membrane
HW10_RS06610	COG1073	alpha beta
HW10_RS06610	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HW10_RS06625	COG2885	chlorophyll binding
HW10_RS06640	COG0789	Transcriptional regulator
HW10_RS06660	COG1214	PFAM Peptidase M22, glycoprotease
HW10_RS06670	COG1801	Protein of unknown function DUF72
HW10_RS06675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HW10_RS06700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS06745	COG2166	iron-sulfur cluster assembly
HW10_RS06760	COG1280	lysine exporter protein (LysE YggA)
HW10_RS06765	COG1393	Belongs to the ArsC family
HW10_RS06785	COG0025	NhaP-type Na H and K H
HW10_RS06790	COG0436	Aminotransferase
HW10_RS06800	COG0024	Methionine aminopeptidase
HW10_RS06880	COG1115	amino acid carrier protein
HW10_RS06930	COG2391	methyltransferase activity
HW10_RS06935	COG0583	DNA-binding transcription factor activity
HW10_RS06940	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HW10_RS06945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HW10_RS07000	COG1546	Belongs to the CinA family
HW10_RS07020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HW10_RS07025	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HW10_RS07030	COG3530	Putative quorum-sensing-regulated virulence factor
HW10_RS07045	COG1177	transmembrane transport
HW10_RS07050	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS07060	COG3148	PFAM DTW domain containing protein
HW10_RS07080	COG0069	glutamate synthase activity
HW10_RS07105	COG0531	amino acid
HW10_RS07110	COG2169	Transcriptional regulator
HW10_RS07110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW10_RS07115	COG0477	Major facilitator Superfamily
HW10_RS07125	COG0583	DNA-binding transcription factor activity
HW10_RS07130	COG1960	acyl-CoA dehydrogenase activity
HW10_RS07135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW10_RS07140	COG1024	Enoyl-CoA hydratase
HW10_RS07145	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS07150	COG0183	Belongs to the thiolase family
HW10_RS07160	COG0583	DNA-binding transcription factor activity
HW10_RS07200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HW10_RS07250	COG2814	Major facilitator Superfamily
HW10_RS07290	COG0583	DNA-binding transcription factor activity
HW10_RS07300	COG0084	hydrolase, TatD family'
HW10_RS07305	COG1609	Transcriptional regulator
HW10_RS07315	COG1105	Belongs to the carbohydrate kinase PfkB family
HW10_RS07320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HW10_RS07320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HW10_RS07320	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HW10_RS07435	COG3842	ATPase activity
HW10_RS07455	COG0243	molybdopterin cofactor binding
HW10_RS07460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HW10_RS07465	COG2223	nitrite transmembrane transporter activity
HW10_RS07480	COG0450	alkyl hydroperoxide reductase
HW10_RS07510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS07545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HW10_RS07550	COG2264	protein methyltransferase activity
HW10_RS07560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HW10_RS07615	COG0489	protein tyrosine kinase activity
HW10_RS07665	COG0791	NLP P60 protein
HW10_RS07685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HW10_RS07690	COG0668	transmembrane transport
HW10_RS07695	COG0477	Major facilitator Superfamily
HW10_RS07700	COG0513	Belongs to the DEAD box helicase family
HW10_RS07720	COG0784	Response regulator, receiver
HW10_RS07720	COG5002	protein histidine kinase activity
HW10_RS07720	COG2205	protein histidine kinase activity
HW10_RS07725	COG1363	Peptidase, m42
HW10_RS07730	COG0189	ligase activity
HW10_RS07730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HW10_RS07735	COG0367	asparagine synthase
HW10_RS07765	COG0183	Belongs to the thiolase family
HW10_RS07785	COG0450	alkyl hydroperoxide reductase
HW10_RS07790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS07795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS07805	COG0431	NADPH-dependent FMN reductase
HW10_RS07810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS07820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS07845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HW10_RS07870	COG0583	DNA-binding transcription factor activity
HW10_RS07875	COG1380	Effector of murein hydrolase LrgA
HW10_RS07880	COG1346	cytolysis
HW10_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS07905	COG1024	Enoyl-CoA hydratase
HW10_RS07915	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HW10_RS07960	COG0508	dehydrogenase complex catalyzes the overall conversion of
HW10_RS08000	COG1629	transport
HW10_RS08055	COG0583	DNA-binding transcription factor activity
HW10_RS08130	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HW10_RS08135	COG3639	organic phosphonate transmembrane transporter activity
HW10_RS08140	COG2188	Transcriptional regulator
HW10_RS08145	COG3624	Phosphonate C-P lyase system protein PhnG
HW10_RS08155	COG3626	phosphonate metabolism
HW10_RS08160	COG3627	carbon phosphorus lyase activity
HW10_RS08165	COG4107	phosphonate C-P lyase system protein PhnK
HW10_RS08170	COG4778	phosphonate C-P lyase system protein PhnL
HW10_RS08175	COG3454	Phosphonate metabolism
HW10_RS08185	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HW10_RS08260	COG0697	spore germination
HW10_RS08285	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HW10_RS08305	COG0835	chemotaxis
HW10_RS08305	COG0784	Response regulator, receiver
HW10_RS08320	COG0745	RESPONSE REGULATOR receiver
HW10_RS08330	COG0514	ATP-dependent DNA helicase (RecQ)
HW10_RS08335	COG4251	negative regulation of phosphorylation
HW10_RS08335	COG5001	Diguanylate cyclase
HW10_RS08335	COG2203	Gaf domain
HW10_RS08335	COG3706	GGDEF domain
HW10_RS08360	COG1752	Esterase of the alpha-beta hydrolase superfamily
HW10_RS08400	COG2124	cytochrome p450
HW10_RS08405	COG4221	oxidoreductase activity
HW10_RS08450	COG0583	DNA-binding transcription factor activity
HW10_RS08480	COG3639	organic phosphonate transmembrane transporter activity
HW10_RS08490	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HW10_RS08495	COG2084	Dehydrogenase
HW10_RS08510	COG0589	response to stress
HW10_RS08550	COG2814	Major facilitator Superfamily
HW10_RS08555	COG2030	dehydratase
HW10_RS08560	COG2267	carboxylic ester hydrolase activity
HW10_RS08565	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS08570	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS08585	COG1643	Atp-dependent helicase
HW10_RS08595	COG0537	adenosine 5'-monophosphoramidase activity
HW10_RS08650	COG1595	DNA-templated transcription, initiation
HW10_RS08725	COG1201	RNA secondary structure unwinding
HW10_RS08730	COG2205	protein histidine kinase activity
HW10_RS08730	COG0784	Response regulator, receiver
HW10_RS08745	COG4772	TonB-dependent receptor
HW10_RS08760	COG2076	Multidrug Resistance protein
HW10_RS08765	COG0385	Bile acid
HW10_RS08815	COG2200	EAL domain
HW10_RS08825	COG0604	alcohol dehydrogenase
HW10_RS08825	COG3321	synthase
HW10_RS08830	COG0560	Phosphoserine phosphatase
HW10_RS08845	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW10_RS08875	COG0564	pseudouridine synthase activity
HW10_RS08885	COG2894	cell division
HW10_RS08895	COG1560	Kdo2-lipid A biosynthetic process
HW10_RS08910	COG2853	Lipoprotein
HW10_RS08930	COG3162	membrane
HW10_RS08935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS08965	COG1132	(ABC) transporter
HW10_RS08975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW10_RS09000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HW10_RS09015	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HW10_RS09015	COG0438	transferase activity, transferring glycosyl groups
HW10_RS09045	COG1127	ABC transporter
HW10_RS09050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HW10_RS09055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HW10_RS09060	COG0727	PFAM Uncharacterised protein family (UPF0153)
HW10_RS09065	COG0778	Nitroreductase
HW10_RS09085	COG0745	RESPONSE REGULATOR receiver
HW10_RS09095	COG2350	Protein conserved in bacteria
HW10_RS09105	COG0613	PHP domain protein
HW10_RS09110	COG0009	L-threonylcarbamoyladenylate synthase
HW10_RS09115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HW10_RS09120	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HW10_RS09170	COG1175	transmembrane transport
HW10_RS09175	COG0395	ABC-type sugar transport system, permease component
HW10_RS09180	COG3842	ATPase activity
HW10_RS09195	COG0676	glucose-6-phosphate 1-epimerase activity
HW10_RS09240	COG0786	glutamate:sodium symporter activity
HW10_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS09270	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS09300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HW10_RS09375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HW10_RS09415	COG0583	DNA-binding transcription factor activity
HW10_RS09450	COG0596	Alpha beta hydrolase
HW10_RS09455	COG0800	Aldolase
HW10_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS09490	COG0583	DNA-binding transcription factor activity
HW10_RS09495	COG0251	oxidation-reduction process
HW10_RS09515	COG2226	methyltransferase
HW10_RS09555	COG0285	dihydrofolate synthase activity
HW10_RS09560	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HW10_RS09565	COG1286	toxin biosynthetic process
HW10_RS09665	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS09665	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS09690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HW10_RS09700	COG3139	Protein of unknown function (DUF1315)
HW10_RS09710	COG0308	aminopeptidase N
HW10_RS09745	COG0745	RESPONSE REGULATOR receiver
HW10_RS09780	COG0714	Associated with various cellular activities
HW10_RS09800	COG1335	isochorismatase
HW10_RS09810	COG2342	PFAM TM1410 hypothetical-related protein
HW10_RS09835	COG0297	glycogen (starch) synthase activity
HW10_RS09885	COG3130	regulation of translation
HW10_RS09900	COG2027	D-alanyl-D-alanine carboxypeptidase
HW10_RS09905	COG3171	Protein conserved in bacteria
HW10_RS09910	COG2197	response regulator
HW10_RS09915	COG2205	protein histidine kinase activity
HW10_RS09915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS09940	COG0004	ammonium transporteR
HW10_RS09950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS09960	COG0625	glutathione transferase activity
HW10_RS09965	COG1309	transcriptional regulator
HW10_RS09995	COG0521	Mo-molybdopterin cofactor biosynthetic process
HW10_RS10015	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HW10_RS10020	COG1070	Carbohydrate kinase
HW10_RS10040	COG0741	lytic transglycosylase activity
HW10_RS10045	COG0488	(ABC) transporter
HW10_RS10055	COG0589	response to stress
HW10_RS10135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HW10_RS10145	COG1113	amino acid transport
HW10_RS10180	COG1477	protein flavinylation
HW10_RS10195	COG0584	glycerophosphoryl diester phosphodiesterase
HW10_RS10210	COG4591	ABC-type transport system involved in lipoprotein release permease component
HW10_RS10230	COG2333	competence protein COMEC
HW10_RS10230	COG0658	competence protein
HW10_RS10235	COG0811	peptide transport
HW10_RS10240	COG0848	biopolymer transport protein
HW10_RS10260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HW10_RS10270	COG1530	ribonuclease E activity
HW10_RS10290	COG0616	signal peptide processing
HW10_RS10290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HW10_RS10300	COG1399	metal-binding, possibly nucleic acid-binding protein
HW10_RS10330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HW10_RS10340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HW10_RS10360	COG0084	hydrolase, TatD family'
HW10_RS10445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HW10_RS10460	COG0183	Belongs to the thiolase family
HW10_RS10475	COG2233	PERMEase
HW10_RS10485	COG3038	cytochrome b561
HW10_RS10500	COG2814	Major facilitator Superfamily
HW10_RS10505	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS10510	COG1309	transcriptional regulator
HW10_RS10545	COG4160	amino acid transport
HW10_RS10550	COG4215	(ABC) transporter
HW10_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS10560	COG1473	amidohydrolase
HW10_RS10565	COG0583	DNA-binding transcription factor activity
HW10_RS10570	COG0840	transmembrane signaling receptor activity
HW10_RS10600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS10610	COG1120	ATPase activity
HW10_RS10640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS10670	COG2885	chlorophyll binding
HW10_RS10670	COG3047	cAMP biosynthetic process
HW10_RS10675	COG2197	response regulator
HW10_RS10685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS10690	COG1595	DNA-templated transcription, initiation
HW10_RS10705	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS10720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HW10_RS10725	COG1960	acyl-CoA dehydrogenase activity
HW10_RS10730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HW10_RS10745	COG1309	transcriptional regulator
HW10_RS10775	COG0583	DNA-binding transcription factor activity
HW10_RS10785	COG0583	DNA-binding transcription factor activity
HW10_RS10795	COG0714	Associated with various cellular activities
HW10_RS10840	COG0084	hydrolase, TatD family'
HW10_RS10845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HW10_RS10850	COG2259	Doxx family
HW10_RS10865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HW10_RS10880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HW10_RS10885	COG4181	ATPase activity
HW10_RS10925	COG1764	response to oxidative stress
HW10_RS10930	COG1846	Transcriptional regulator
HW10_RS10935	COG0583	DNA-binding transcription factor activity
HW10_RS10945	COG0583	DNA-binding transcription factor activity
HW10_RS10955	COG3214	Protein conserved in bacteria
HW10_RS10960	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HW10_RS10970	COG1024	Enoyl-CoA hydratase
HW10_RS10980	COG3384	dioxygenase
HW10_RS11020	COG2866	Carboxypeptidase
HW10_RS11035	COG0436	Aminotransferase
HW10_RS11045	COG0386	Belongs to the glutathione peroxidase family
HW10_RS11050	COG1846	Transcriptional regulator
HW10_RS11055	COG5002	protein histidine kinase activity
HW10_RS11055	COG2205	protein histidine kinase activity
HW10_RS11055	COG0784	Response regulator, receiver
HW10_RS11060	COG2255	four-way junction helicase activity
HW10_RS11065	COG1956	GAF domain-containing protein
HW10_RS11070	COG0625	glutathione transferase activity
HW10_RS11095	COG2200	EAL domain
HW10_RS11120	COG0625	glutathione transferase activity
HW10_RS11125	COG1131	(ABC) transporter
HW10_RS11130	COG0842	Transport permease protein
HW10_RS11175	COG2188	Transcriptional regulator
HW10_RS11185	COG2853	Lipoprotein
HW10_RS11195	COG0745	RESPONSE REGULATOR receiver
HW10_RS11435	COG3179	chitinase
HW10_RS11460	COG1335	isochorismatase
HW10_RS11490	COG5434	Belongs to the glycosyl hydrolase 28 family
HW10_RS11520	COG3655	Transcriptional regulator
HW10_RS11565	COG2116	formate transmembrane transporter activity
HW10_RS11570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS11625	COG1051	belongs to the nudix hydrolase family
HW10_RS11635	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS11635	COG1024	Enoyl-CoA hydratase
HW10_RS11645	COG2837	iron assimilation
HW10_RS11730	COG1238	metal cluster binding
HW10_RS11740	COG1295	ribonuclease BN
HW10_RS11770	COG0024	Methionine aminopeptidase
HW10_RS11865	COG3012	SEC-C Motif Domain Protein
HW10_RS11880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HW10_RS11885	COG0732	type I restriction modification DNA specificity domain
HW10_RS11890	COG1401	restriction endodeoxyribonuclease activity
HW10_RS11915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS11920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HW10_RS11950	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HW10_RS11950	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HW10_RS11960	COG0542	response to heat
HW10_RS11995	COG0789	Transcriptional regulator
HW10_RS12005	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS12005	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS12010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HW10_RS12015	COG0243	molybdopterin cofactor binding
HW10_RS12040	COG1280	lysine exporter protein (LysE YggA)
HW10_RS12055	COG0542	response to heat
HW10_RS12130	COG1607	acyl-coa hydrolase
HW10_RS12135	COG1959	2 iron, 2 sulfur cluster binding
HW10_RS12145	COG2819	hydrolase of the alpha beta superfamily
HW10_RS12190	COG0583	DNA-binding transcription factor activity
HW10_RS12210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW10_RS12215	COG1459	type II secretion system
HW10_RS12225	COG2165	general secretion pathway protein
HW10_RS12265	COG0720	synthase
HW10_RS12270	COG3604	Transcriptional regulator
HW10_RS12330	COG0840	transmembrane signaling receptor activity
HW10_RS12335	COG2056	Na+-H+ antiporter family
HW10_RS12355	COG2226	methyltransferase
HW10_RS12455	COG2153	protein acetylation
HW10_RS12460	COG2850	peptidyl-arginine hydroxylation
HW10_RS12500	COG1278	Cold shock
HW10_RS12510	COG0542	response to heat
HW10_RS12515	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HW10_RS12530	COG0492	ferredoxin-NADP+ reductase activity
HW10_RS12545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HW10_RS12560	COG0435	Glutathione S-transferase
HW10_RS12565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HW10_RS12570	COG2920	part of a sulfur-relay system
HW10_RS12630	COG0583	DNA-binding transcription factor activity
HW10_RS12635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS12640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS12650	COG1960	acyl-CoA dehydrogenase activity
HW10_RS12655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS12665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS12680	COG2197	response regulator
HW10_RS12685	COG4771	TonB-dependent receptor
HW10_RS12740	COG0784	Response regulator, receiver
HW10_RS12740	COG2198	Histidine kinase
HW10_RS12740	COG2205	protein histidine kinase activity
HW10_RS12740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS12760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW10_RS12775	COG1522	sequence-specific DNA binding
HW10_RS12805	COG4191	Histidine kinase
HW10_RS12830	COG2203	Gaf domain
HW10_RS12830	COG5001	Diguanylate cyclase
HW10_RS12830	COG3706	GGDEF domain
HW10_RS12830	COG4251	negative regulation of phosphorylation
HW10_RS12840	COG0659	secondary active sulfate transmembrane transporter activity
HW10_RS12875	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS12885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HW10_RS12895	COG0183	Belongs to the thiolase family
HW10_RS12900	COG1960	acyl-CoA dehydrogenase activity
HW10_RS12950	COG0729	surface antigen
HW10_RS12960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HW10_RS12965	COG2267	carboxylic ester hydrolase activity
HW10_RS12970	COG2453	phosphatase
HW10_RS12970	COG0671	phosphoesterase, PA-phosphatase related
HW10_RS12985	COG4589	Belongs to the CDS family
HW10_RS12990	COG0667	Aldo Keto reductase
HW10_RS13000	COG1115	amino acid carrier protein
HW10_RS13010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HW10_RS13040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS13045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS13050	COG1538	Outer membrane efflux protein
HW10_RS13110	COG0543	2 iron, 2 sulfur cluster binding
HW10_RS13110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HW10_RS13115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HW10_RS13120	COG4638	Rieske (2fe-2S)
HW10_RS13145	COG4948	Mandelate Racemase Muconate Lactonizing
HW10_RS13155	COG3485	protocatechuate 3,4-dioxygenase
HW10_RS13190	COG2807	transmembrane transport
HW10_RS13195	COG0590	tRNA wobble adenosine to inosine editing
HW10_RS13210	COG2318	DinB family
HW10_RS13275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS13280	COG2863	cytochrome
HW10_RS13285	COG3258	Cytochrome c
HW10_RS13290	COG0642	Histidine kinase
HW10_RS13325	COG0625	glutathione transferase activity
HW10_RS13345	COG0583	DNA-binding transcription factor activity
HW10_RS13350	COG1595	DNA-templated transcription, initiation
HW10_RS13355	COG3712	iron ion homeostasis
HW10_RS13400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS13410	COG2382	esterase
HW10_RS13430	COG0583	DNA-binding transcription factor activity
HW10_RS13455	COG1760	l-serine dehydratase
HW10_RS13460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HW10_RS13495	COG2217	Heavy metal translocating P-type atpase
HW10_RS13510	COG0583	DNA-binding transcription factor activity
HW10_RS13530	COG1566	PFAM secretion protein HlyD family protein
HW10_RS13620	COG1335	isochorismatase
HW10_RS13630	COG0583	DNA-binding transcription factor activity
HW10_RS13670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HW10_RS13675	COG1121	(ABC) transporter
HW10_RS13770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS13795	COG0735	belongs to the Fur family
HW10_RS13805	COG1304	FMN binding
HW10_RS13835	COG4566	intracellular signal transduction
HW10_RS13925	COG3829	transcription factor binding
HW10_RS13950	COG3829	transcription factor binding
HW10_RS13955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW10_RS13960	COG0584	glycerophosphoryl diester phosphodiesterase
HW10_RS13965	COG2011	ABC-type metal ion transport system permease component
HW10_RS13975	COG1464	Belongs to the NlpA lipoprotein family
HW10_RS14005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW10_RS14010	COG1070	Carbohydrate kinase
HW10_RS14015	COG0246	Mannitol dehydrogenase
HW10_RS14030	COG1175	transmembrane transport
HW10_RS14050	COG4771	TonB-dependent receptor
HW10_RS14065	COG1917	Cupin 2, conserved barrel domain protein
HW10_RS14065	COG4977	sequence-specific DNA binding
HW10_RS14080	COG1116	anion transmembrane transporter activity
HW10_RS14085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW10_RS14090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS14110	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS14125	COG3265	gluconokinase activity
HW10_RS14130	COG1609	Transcriptional regulator
HW10_RS14140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS14145	COG0583	DNA-binding transcription factor activity
HW10_RS14165	COG1396	sequence-specific DNA binding
HW10_RS14175	COG2175	clavaminate synthase activity
HW10_RS14185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HW10_RS14190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS14215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS14215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW10_RS14225	COG3469	chitinase activity
HW10_RS14230	COG2188	Transcriptional regulator
HW10_RS14235	COG1053	succinate dehydrogenase
HW10_RS14250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW10_RS14285	COG4772	TonB-dependent receptor
HW10_RS14330	COG0431	NADPH-dependent FMN reductase
HW10_RS14335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HW10_RS14345	COG0640	Transcriptional regulator
HW10_RS14350	COG2207	Transcriptional regulator
HW10_RS14355	COG1064	alcohol dehydrogenase
HW10_RS14380	COG1309	transcriptional regulator
HW10_RS14390	COG2329	Antibiotic biosynthesis monooxygenase
HW10_RS14425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW10_RS14435	COG1609	Transcriptional regulator
HW10_RS14470	COG0252	asparaginase activity
HW10_RS14475	COG1115	amino acid carrier protein
HW10_RS14520	COG1053	succinate dehydrogenase
HW10_RS14530	COG0728	peptidoglycan biosynthetic process
HW10_RS14595	COG2258	MOSC domain
HW10_RS14640	COG2801	Transposase and inactivated derivatives
HW10_RS14685	COG2508	Transcriptional regulator
HW10_RS14695	COG4447	cellulose binding
HW10_RS14700	COG2409	Drug exporters of the RND superfamily
HW10_RS14720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS14735	COG2072	flavoprotein involved in K transport
HW10_RS14750	COG0531	amino acid
HW10_RS14755	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS14760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HW10_RS14775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS14780	COG3162	membrane
HW10_RS14785	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS14820	COG3008	intermembrane lipid transfer
HW10_RS14825	COG2995	paraquat-inducible protein a
HW10_RS14830	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS14840	COG4948	Mandelate Racemase Muconate Lactonizing
HW10_RS14845	COG2271	Major facilitator Superfamily
HW10_RS14860	COG3618	amidohydrolase
HW10_RS14865	COG2271	Major facilitator Superfamily
HW10_RS14900	COG0765	amino acid transport
HW10_RS14905	COG0765	amino acid transport
HW10_RS14920	COG2084	Dehydrogenase
HW10_RS14930	COG2130	NADP-dependent
HW10_RS14935	COG1309	transcriptional regulator
HW10_RS14955	COG0366	Alpha amylase catalytic
HW10_RS14960	COG0517	IMP dehydrogenase activity
HW10_RS14995	COG2890	protein-(glutamine-N5) methyltransferase activity
HW10_RS15010	COG0784	Response regulator, receiver
HW10_RS15010	COG4191	Histidine kinase
HW10_RS15040	COG1363	Peptidase, m42
HW10_RS15085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HW10_RS15130	COG3568	Endonuclease Exonuclease Phosphatase
HW10_RS15135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW10_RS15140	COG0392	lysyltransferase activity
HW10_RS15150	COG0366	Alpha amylase catalytic
HW10_RS15170	COG1285	pathogenesis
HW10_RS15195	COG0058	SHG alpha-glucan phosphorylase activity
HW10_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS15245	COG2323	membrane
HW10_RS15265	COG3121	Chaperone
HW10_RS15275	COG3188	usher protein
HW10_RS15280	COG3121	Chaperone
HW10_RS15290	COG3969	phosphoadenosine phosphosulfate
HW10_RS15300	COG1475	DNA binding
HW10_RS15305	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS15310	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW10_RS15315	COG0583	DNA-binding transcription factor activity
HW10_RS15340	COG1063	alcohol dehydrogenase
HW10_RS15355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW10_RS15355	COG2169	Transcriptional regulator
HW10_RS15375	COG0583	DNA-binding transcription factor activity
HW10_RS15380	COG2814	Major facilitator Superfamily
HW10_RS15400	COG1984	allophanate hydrolase subunit 2
HW10_RS15410	COG0028	Belongs to the TPP enzyme family
HW10_RS15420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HW10_RS15425	COG1045	serine acetyltransferase
HW10_RS15430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HW10_RS15450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS15455	COG0300	oxidoreductase activity
HW10_RS15495	COG2814	Major facilitator Superfamily
HW10_RS15505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW10_RS15525	COG0596	Alpha beta hydrolase
HW10_RS15530	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HW10_RS15535	COG0367	asparagine synthase
HW10_RS15545	COG1522	sequence-specific DNA binding
HW10_RS15565	COG1113	amino acid transport
HW10_RS15575	COG2010	Cytochrome c
HW10_RS15580	COG2010	Cytochrome c
HW10_RS15600	COG3153	acetyltransferase
HW10_RS15600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HW10_RS15605	COG5001	Diguanylate cyclase
HW10_RS15615	COG4206	TonB-dependent receptor
HW10_RS15625	COG2192	nodulation
HW10_RS15630	COG2814	Major facilitator Superfamily
HW10_RS15660	COG1104	cysteine desulfurase activity
HW10_RS15665	COG4172	Belongs to the ABC transporter superfamily
HW10_RS15670	COG4239	(ABC) transporter, permease
HW10_RS15675	COG4174	ABC transporter (Permease)
HW10_RS15685	COG4771	TonB-dependent receptor
HW10_RS15700	COG0583	DNA-binding transcription factor activity
HW10_RS15720	COG1595	DNA-templated transcription, initiation
HW10_RS15735	COG2207	Transcriptional regulator
HW10_RS15760	COG0564	pseudouridine synthase activity
HW10_RS15775	COG0531	amino acid
HW10_RS15780	COG0174	glutamine synthetase
HW10_RS15795	COG0028	Belongs to the TPP enzyme family
HW10_RS15810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS15830	COG1522	sequence-specific DNA binding
HW10_RS15870	COG1309	transcriptional regulator
HW10_RS15875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS15880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS15890	COG3204	pilus organization
HW10_RS15895	COG0789	Transcriptional regulator
HW10_RS15900	COG1960	acyl-CoA dehydrogenase activity
HW10_RS15905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HW10_RS15935	COG0179	Fumarylacetoacetate (FAA) hydrolase
HW10_RS15945	COG2271	Major facilitator Superfamily
HW10_RS15950	COG3290	protein histidine kinase activity
HW10_RS15950	COG3829	transcription factor binding
HW10_RS15955	COG2610	gluconate transmembrane transporter activity
HW10_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS15965	COG2031	fatty acid transporter
HW10_RS15980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HW10_RS15985	COG0583	DNA-binding transcription factor activity
HW10_RS15990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HW10_RS15995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS16015	COG2205	protein histidine kinase activity
HW10_RS16080	COG3851	Histidine kinase
HW10_RS16095	COG2205	protein histidine kinase activity
HW10_RS16095	COG0784	Response regulator, receiver
HW10_RS16115	COG2194	sulfuric ester hydrolase activity
HW10_RS16160	COG0488	(ABC) transporter
HW10_RS16175	COG0583	DNA-binding transcription factor activity
HW10_RS16180	COG1278	Cold shock
HW10_RS16230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW10_RS16235	COG1609	Transcriptional regulator
HW10_RS16240	COG1172	Belongs to the binding-protein-dependent transport system permease family
HW10_RS16245	COG1129	ABC transporter
HW10_RS16255	COG2204	response regulator
HW10_RS16275	COG2010	Cytochrome c
HW10_RS16280	COG0753	catalase activity
HW10_RS16325	COG1944	ATP diphosphatase activity
HW10_RS16345	COG4771	TonB-dependent receptor
HW10_RS16350	COG0275	rRNA processing
HW10_RS16355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HW10_RS16355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW10_RS16370	COG0579	oxidoreductase
HW10_RS16405	COG1595	DNA-templated transcription, initiation
HW10_RS16410	COG3712	iron ion homeostasis
HW10_RS16430	COG2814	Major facilitator Superfamily
HW10_RS16480	COG2197	response regulator
HW10_RS16505	COG2366	antibiotic biosynthetic process
HW10_RS16520	COG0625	glutathione transferase activity
HW10_RS16535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS16540	COG0417	DNA replication proofreading
HW10_RS16585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS16655	COG1309	transcriptional regulator
HW10_RS16675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HW10_RS16680	COG0583	DNA-binding transcription factor activity
HW10_RS16690	COG2354	Protein conserved in bacteria
HW10_RS16695	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS16705	COG2239	Acts as a magnesium transporter
HW10_RS16720	COG4251	negative regulation of phosphorylation
HW10_RS16720	COG2203	Gaf domain
HW10_RS16720	COG5001	Diguanylate cyclase
HW10_RS16720	COG3706	GGDEF domain
HW10_RS16725	COG4977	sequence-specific DNA binding
HW10_RS16730	COG3813	Protein conserved in bacteria
HW10_RS16795	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS16820	COG0604	alcohol dehydrogenase
HW10_RS16825	COG0616	signal peptide processing
HW10_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS16855	COG0583	DNA-binding transcription factor activity
HW10_RS16880	COG1024	Enoyl-CoA hydratase
HW10_RS16890	COG0531	amino acid
HW10_RS16905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HW10_RS16925	COG1388	LysM domain
HW10_RS16925	COG0741	lytic transglycosylase activity
HW10_RS16930	COG4166	transmembrane transport
HW10_RS16935	COG4166	transmembrane transport
HW10_RS16940	COG4174	ABC transporter (Permease)
HW10_RS16945	COG4239	(ABC) transporter, permease
HW10_RS16950	COG4172	Belongs to the ABC transporter superfamily
HW10_RS16960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS16975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HW10_RS17000	COG0745	RESPONSE REGULATOR receiver
HW10_RS17005	COG2205	protein histidine kinase activity
HW10_RS17010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HW10_RS17055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HW10_RS17075	COG0589	response to stress
HW10_RS17100	COG2201	protein-glutamate methylesterase activity
HW10_RS17110	COG2223	nitrite transmembrane transporter activity
HW10_RS17115	COG0515	serine threonine protein kinase
HW10_RS17120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW10_RS17125	COG2146	nitrite reductase [NAD(P)H] activity
HW10_RS17130	COG0243	molybdopterin cofactor binding
HW10_RS17150	COG0668	transmembrane transport
HW10_RS17190	COG4067	protein conserved in archaea
HW10_RS17190	COG0189	ligase activity
HW10_RS17235	COG2909	trisaccharide binding
HW10_RS17240	COG2909	trisaccharide binding
HW10_RS17275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HW10_RS17330	COG0519	Catalyzes the synthesis of GMP from XMP
HW10_RS17345	COG0667	Aldo Keto reductase
HW10_RS17355	COG1024	Enoyl-CoA hydratase
HW10_RS17355	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS17360	COG0183	Belongs to the thiolase family
HW10_RS17380	COG1305	Transglutaminase-like
HW10_RS17390	COG2308	Evidence 4 Homologs of previously reported genes of
HW10_RS17400	COG0505	Belongs to the CarA family
HW10_RS17420	COG1317	bacterial-type flagellum organization
HW10_RS17530	COG4789	Type iii secretion
HW10_RS17580	COG4790	Type iii secretion
HW10_RS17585	COG4794	Type iii secretion
HW10_RS17590	COG4791	protein targeting
HW10_RS17595	COG4792	protein secretion
HW10_RS17675	COG2840	Smr protein MutS2
HW10_RS17695	COG2815	serine threonine protein kinase
HW10_RS17695	COG0515	serine threonine protein kinase
HW10_RS17735	COG2204	response regulator
HW10_RS17780	COG0625	glutathione transferase activity
HW10_RS17785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW10_RS17800	COG3135	benzoate transporter
HW10_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS17815	COG2130	NADP-dependent
HW10_RS17830	COG0840	transmembrane signaling receptor activity
HW10_RS17840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HW10_RS17880	COG0745	RESPONSE REGULATOR receiver
HW10_RS17885	COG2205	protein histidine kinase activity
HW10_RS17910	COG1960	acyl-CoA dehydrogenase activity
HW10_RS17920	COG1024	Enoyl-CoA hydratase
HW10_RS17925	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS17930	COG2186	Transcriptional regulator
HW10_RS17935	COG2807	transmembrane transport
HW10_RS17940	COG0628	permease
HW10_RS17950	COG0625	glutathione transferase activity
HW10_RS17980	COG1022	Amp-dependent synthetase and ligase
HW10_RS18010	COG0784	Response regulator, receiver
HW10_RS18010	COG2205	protein histidine kinase activity
HW10_RS18010	COG5002	protein histidine kinase activity
HW10_RS18050	COG1846	Transcriptional regulator
HW10_RS18055	COG2080	2 iron, 2 sulfur cluster binding
HW10_RS18060	COG2010	Cytochrome c
HW10_RS18060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HW10_RS18065	COG2010	Cytochrome c
HW10_RS18065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HW10_RS18070	COG2207	Transcriptional regulator
HW10_RS18145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HW10_RS18150	COG1053	succinate dehydrogenase
HW10_RS18155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HW10_RS18160	COG2009	succinate dehydrogenase
HW10_RS18190	COG2084	Dehydrogenase
HW10_RS18205	COG3738	Protein conserved in bacteria
HW10_RS18235	COG0251	oxidation-reduction process
HW10_RS18240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS18250	COG0174	glutamine synthetase
HW10_RS18255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS18275	COG0840	transmembrane signaling receptor activity
HW10_RS18290	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS18305	COG2010	Cytochrome c
HW10_RS18310	COG3278	Belongs to the heme-copper respiratory oxidase family
HW10_RS18325	COG2010	Cytochrome c
HW10_RS18335	COG0348	domain, Protein
HW10_RS18345	COG2217	Heavy metal translocating P-type atpase
HW10_RS18385	COG2076	Multidrug Resistance protein
HW10_RS18415	COG1960	acyl-CoA dehydrogenase activity
HW10_RS18430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HW10_RS18465	COG1196	nuclear chromosome segregation
HW10_RS18495	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS18500	COG1247	-acetyltransferase
HW10_RS18545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HW10_RS18555	COG0384	phenazine biosynthesis protein PhzF
HW10_RS18585	COG5006	permease, DMT superfamily
HW10_RS18600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HW10_RS18615	COG3795	YCII-related domain
HW10_RS18625	COG2814	Major facilitator Superfamily
HW10_RS18630	COG4941	Belongs to the sigma-70 factor family
HW10_RS18640	COG3795	YCII-related domain
HW10_RS18650	COG2197	response regulator
HW10_RS18655	COG1982	Orn Lys Arg decarboxylase major
HW10_RS18660	COG0189	ligase activity
HW10_RS18665	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS18680	COG0765	amino acid transport
HW10_RS18685	COG0765	amino acid transport
HW10_RS18690	COG1126	abc transporter atp-binding protein
HW10_RS18720	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS18740	COG1253	flavin adenine dinucleotide binding
HW10_RS18745	COG0300	oxidoreductase activity
HW10_RS18755	COG0583	DNA-binding transcription factor activity
HW10_RS18765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HW10_RS18770	COG4319	ketosteroid isomerase
HW10_RS18785	COG4774	siderophore transport
HW10_RS18835	COG2814	Major facilitator Superfamily
HW10_RS18855	COG0583	DNA-binding transcription factor activity
HW10_RS18865	COG0121	glutamine amidotransferase
HW10_RS18895	COG3712	iron ion homeostasis
HW10_RS18900	COG1595	DNA-templated transcription, initiation
HW10_RS18915	COG1230	cation diffusion facilitator family transporter
HW10_RS18950	COG2252	PERMEase
HW10_RS19010	COG2233	PERMEase
HW10_RS19025	COG1309	transcriptional regulator
HW10_RS19035	COG3960	tartronate-semialdehyde synthase activity
HW10_RS19040	COG3622	Belongs to the hyi family
HW10_RS19045	COG2084	Dehydrogenase
HW10_RS19055	COG0469	pyruvate kinase activity
HW10_RS19060	COG4413	Urea transporter
HW10_RS19065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HW10_RS19080	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HW10_RS19090	COG3192	ethanolamine utilization protein
HW10_RS19105	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS19110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HW10_RS19185	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HW10_RS19200	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS19230	COG0835	chemotaxis
HW10_RS19240	COG1192	Involved in chromosome partitioning
HW10_RS19245	COG1360	Flagellar Motor Protein
HW10_RS19250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HW10_RS19260	COG0643	Histidine kinase
HW10_RS19260	COG2198	Histidine kinase
HW10_RS19260	COG0784	Response regulator, receiver
HW10_RS19290	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HW10_RS19295	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HW10_RS19315	COG1987	bacterial-type flagellum assembly
HW10_RS19355	COG2832	Protein of unknown function (DUF454)
HW10_RS19370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS19375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS19385	COG3300	MHYT domain
HW10_RS19385	COG5001	Diguanylate cyclase
HW10_RS19420	COG0488	(ABC) transporter
HW10_RS19475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS19485	COG0583	DNA-binding transcription factor activity
HW10_RS19500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HW10_RS19515	COG1196	nuclear chromosome segregation
HW10_RS19515	COG3264	Mechanosensitive ion channel
HW10_RS19520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HW10_RS19520	COG0116	Belongs to the methyltransferase superfamily
HW10_RS19530	COG0210	DNA helicase
HW10_RS19555	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HW10_RS19605	COG0438	transferase activity, transferring glycosyl groups
HW10_RS19610	COG0463	Glycosyl transferase, family 2
HW10_RS19615	COG0438	transferase activity, transferring glycosyl groups
HW10_RS19640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HW10_RS19650	COG1450	Type ii and iii secretion system protein
HW10_RS19700	COG1960	acyl-CoA dehydrogenase activity
HW10_RS19720	COG0406	alpha-ribazole phosphatase activity
HW10_RS19750	COG0778	Nitroreductase
HW10_RS19765	COG4206	TonB-dependent receptor
HW10_RS19775	COG1802	Transcriptional regulator
HW10_RS19785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS19820	COG0477	Major facilitator Superfamily
HW10_RS19840	COG0765	amino acid transport
HW10_RS19850	COG1126	abc transporter atp-binding protein
HW10_RS19860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW10_RS19865	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS19925	COG4191	Histidine kinase
HW10_RS19925	COG0784	Response regulator, receiver
HW10_RS19965	COG1289	transmembrane transporter activity
HW10_RS19980	COG2207	Transcriptional regulator
HW10_RS20000	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW10_RS20005	COG2957	Belongs to the agmatine deiminase family
HW10_RS20020	COG2957	Belongs to the agmatine deiminase family
HW10_RS20025	COG0583	DNA-binding transcription factor activity
HW10_RS20035	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HW10_RS20060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HW10_RS20070	COG0318	PFAM AMP-dependent synthetase and ligase
HW10_RS20075	COG0367	asparagine synthase
HW10_RS20085	COG2211	Major facilitator Superfamily
HW10_RS20135	COG1335	isochorismatase
HW10_RS20140	COG0583	DNA-binding transcription factor activity
HW10_RS20150	COG0791	NLP P60 protein
HW10_RS20155	COG0791	NLP P60 protein
HW10_RS20165	COG3829	transcription factor binding
HW10_RS20180	COG2818	Glycosylase
HW10_RS20205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW10_RS20210	COG1960	acyl-CoA dehydrogenase activity
HW10_RS20220	COG0625	glutathione transferase activity
HW10_RS20245	COG5002	protein histidine kinase activity
HW10_RS20245	COG3447	MASE1 domain protein
HW10_RS20245	COG5001	Diguanylate cyclase
HW10_RS20265	COG4459	periplasmic nitrate reductase
HW10_RS20270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW10_RS20270	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW10_RS20275	COG3062	negative regulation of establishment of protein localization
HW10_RS20285	COG3043	anaerobic respiration
HW10_RS20290	COG3005	denitrification pathway
HW10_RS20295	COG2951	lytic endotransglycosylase activity
HW10_RS20300	COG0861	Integral membrane protein TerC family
HW10_RS20325	COG2977	Belongs to the P-Pant transferase superfamily
HW10_RS20330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HW10_RS20345	COG2226	methyltransferase
HW10_RS20360	COG2205	protein histidine kinase activity
HW10_RS20365	COG0745	RESPONSE REGULATOR receiver
HW10_RS20370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HW10_RS20370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW10_RS20375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW10_RS20380	COG1943	Transposase
HW10_RS20405	COG4104	PAAR repeat-containing protein
HW10_RS20420	COG0531	amino acid
HW10_RS20450	COG0583	DNA-binding transcription factor activity
HW10_RS20455	COG3257	ureidoglycine aminohydrolase activity
HW10_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS20470	COG0604	alcohol dehydrogenase
HW10_RS20470	COG3321	synthase
HW10_RS20475	COG2197	response regulator
HW10_RS20515	COG0583	DNA-binding transcription factor activity
HW10_RS20520	COG0667	Aldo Keto reductase
HW10_RS20550	COG0242	peptide deformylase activity
HW10_RS20560	COG2199	diguanylate cyclase activity
HW10_RS20565	COG2885	chlorophyll binding
HW10_RS20595	COG1132	(ABC) transporter
HW10_RS20610	COG4628	conserved protein (DUF2132)
HW10_RS20615	COG2133	pyrroloquinoline quinone binding
HW10_RS20630	COG2207	Transcriptional regulator
HW10_RS20635	COG0477	Major facilitator Superfamily
HW10_RS20650	COG2882	bacterial-type flagellum organization
HW10_RS20710	COG1334	flagellar protein FlaG
HW10_RS20770	COG4787	bacterial-type flagellum-dependent cell motility
HW10_RS20780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HW10_RS20790	COG1815	bacterial-type flagellum-dependent cell motility
HW10_RS20840	COG0326	Molecular chaperone. Has ATPase activity
HW10_RS20855	COG3189	MarR family transcriptional regulator
HW10_RS20875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HW10_RS20890	COG2212	antiporter activity
HW10_RS20895	COG1863	multisubunit Na H antiporter MnhE subunit
HW10_RS20900	COG0651	ATP synthesis coupled electron transport
HW10_RS20905	COG1006	Multisubunit Na H antiporter MnhC subunit
HW10_RS20910	COG2111	Na H antiporter
HW10_RS20910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HW10_RS20915	COG3133	Outer membrane lipoprotein
HW10_RS20925	COG1929	Belongs to the glycerate kinase type-1 family
HW10_RS20930	COG2610	gluconate transmembrane transporter activity
HW10_RS20935	COG3835	regulator
HW10_RS20945	COG2885	chlorophyll binding
HW10_RS20960	COG1199	ATP-dependent helicase activity
HW10_RS21000	COG2860	membrane
HW10_RS21015	COG0653	protein targeting
HW10_RS21020	COG0625	glutathione transferase activity
HW10_RS21045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS21050	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS21075	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS21080	COG1960	acyl-CoA dehydrogenase activity
HW10_RS21085	COG1024	Enoyl-CoA hydratase
HW10_RS21090	COG1960	acyl-CoA dehydrogenase activity
HW10_RS21100	COG2814	Major facilitator Superfamily
HW10_RS21105	COG2030	dehydratase
HW10_RS21115	COG0183	Belongs to the thiolase family
HW10_RS21145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HW10_RS21150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HW10_RS21165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HW10_RS21175	COG0425	Belongs to the sulfur carrier protein TusA family
HW10_RS21230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW10_RS21235	COG3188	usher protein
HW10_RS21255	COG1051	belongs to the nudix hydrolase family
HW10_RS21280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW10_RS21280	COG0475	glutathione-regulated potassium exporter activity
HW10_RS21295	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS21305	COG0235	Class ii aldolase
HW10_RS21315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW10_RS21320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS21330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW10_RS21340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HW10_RS21355	COG0602	queuosine metabolic process
HW10_RS21360	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HW10_RS21390	COG0824	Thioesterase
HW10_RS21420	COG0783	Belongs to the Dps family
HW10_RS21465	COG3118	belongs to the thioredoxin family
HW10_RS21500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HW10_RS21520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HW10_RS21560	COG3122	Protein conserved in bacteria
HW10_RS21570	COG3956	TIGRFAM MazG family protein
HW10_RS21575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW10_RS21605	COG5002	protein histidine kinase activity
HW10_RS21605	COG0784	Response regulator, receiver
HW10_RS21605	COG2205	protein histidine kinase activity
HW10_RS21610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HW10_RS21660	COG3038	cytochrome b561
HW10_RS21680	COG4807	Protein conserved in bacteria
HW10_RS21690	COG2239	Acts as a magnesium transporter
HW10_RS21760	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HW10_RS21855	COG2301	Belongs to the HpcH HpaI aldolase family
HW10_RS21865	COG2079	MmgE PrpD family protein
HW10_RS21875	COG1960	acyl-CoA dehydrogenase activity
HW10_RS21880	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HW10_RS21885	COG0583	DNA-binding transcription factor activity
HW10_RS21890	COG0583	DNA-binding transcription factor activity
HW10_RS21950	COG1113	amino acid transport
HW10_RS21970	COG0604	alcohol dehydrogenase
HW10_RS21970	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS21970	COG3321	synthase
HW10_RS21980	COG5002	protein histidine kinase activity
HW10_RS21980	COG5001	Diguanylate cyclase
HW10_RS22000	COG0271	Belongs to the BolA IbaG family
HW10_RS22040	COG0492	ferredoxin-NADP+ reductase activity
HW10_RS22045	COG0450	alkyl hydroperoxide reductase
HW10_RS22050	COG3447	MASE1 domain protein
HW10_RS22050	COG5002	protein histidine kinase activity
HW10_RS22050	COG5001	Diguanylate cyclase
HW10_RS22080	COG1307	EDD domain protein, DegV family
HW10_RS22090	COG1309	transcriptional regulator
HW10_RS22095	COG0386	Belongs to the glutathione peroxidase family
HW10_RS22120	COG0204	Acyl-transferase
HW10_RS22125	COG2885	chlorophyll binding
HW10_RS22130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW10_RS22145	COG2267	carboxylic ester hydrolase activity
HW10_RS22170	COG4974	Belongs to the 'phage' integrase family
HW10_RS22215	COG0515	serine threonine protein kinase
HW10_RS22240	COG1196	nuclear chromosome segregation
HW10_RS22260	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HW10_RS22275	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HW10_RS22320	COG4735	regulation of single-species biofilm formation
HW10_RS22325	COG4735	regulation of single-species biofilm formation
HW10_RS22400	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HW10_RS22435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HW10_RS22450	COG0546	phosphoglycolate phosphatase activity
HW10_RS22465	COG3023	N-Acetylmuramoyl-L-alanine amidase
HW10_RS22480	COG0656	L-ascorbic acid biosynthetic process
HW10_RS22505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS22515	COG1802	Transcriptional regulator
HW10_RS22525	COG0372	Belongs to the citrate synthase family
HW10_RS22540	COG2079	MmgE PrpD family protein
HW10_RS22555	COG1113	amino acid transport
HW10_RS22585	COG0583	DNA-binding transcription factor activity
HW10_RS22590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW10_RS22600	COG4206	TonB-dependent receptor
HW10_RS22610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HW10_RS22675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HW10_RS22755	COG3180	Ammonia monooxygenase
HW10_RS22765	COG2720	vancomycin resistance protein
HW10_RS22780	COG1960	acyl-CoA dehydrogenase activity
HW10_RS22785	COG1024	Enoyl-CoA hydratase
HW10_RS22805	COG2910	NAD(P)H-binding
HW10_RS22810	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HW10_RS22910	COG0583	DNA-binding transcription factor activity
HW10_RS22925	COG0463	Glycosyl transferase, family 2
HW10_RS22930	COG0154	amidase activity
HW10_RS22950	COG0583	DNA-binding transcription factor activity
HW10_RS22960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW10_RS22995	COG2831	hemolysin activation secretion protein
HW10_RS23140	COG0420	3'-5' exonuclease activity
HW10_RS23150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HW10_RS23155	COG1074	ATP-dependent DNA helicase activity
HW10_RS23160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HW10_RS23165	COG0095	Lipoate-protein ligase
HW10_RS23170	COG0697	spore germination
HW10_RS23185	COG0840	transmembrane signaling receptor activity
HW10_RS23195	COG0306	phosphate transporter
HW10_RS23255	COG4964	Belongs to the GSP D family
HW10_RS23275	COG0433	COG0433 Predicted ATPase
HW10_RS23315	COG0788	formyltetrahydrofolate deformylase activity
HW10_RS23325	COG2925	Exonuclease
HW10_RS23355	COG0714	Associated with various cellular activities
HW10_RS23385	COG0589	response to stress
HW10_RS23395	COG1024	Enoyl-CoA hydratase
HW10_RS23405	COG3706	GGDEF domain
HW10_RS23425	COG0693	protein deglycase activity
HW10_RS23440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW10_RS23455	COG0154	amidase activity
HW10_RS23465	COG1473	amidohydrolase
HW10_RS23480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HW10_RS23485	COG0426	domain, Protein
HW10_RS23485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HW10_RS23505	COG0589	response to stress
HW10_RS23520	COG2814	Major facilitator Superfamily
HW10_RS23525	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS23540	COG1918	ferrous iron import across plasma membrane
HW10_RS23555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HW10_RS23595	COG1704	LemA family
HW10_RS23620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS23625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS23640	COG3642	lipopolysaccharide core region biosynthetic process
HW10_RS23650	COG2205	protein histidine kinase activity
HW10_RS23655	COG0745	RESPONSE REGULATOR receiver
HW10_RS23690	COG3030	protein affecting phage T7 exclusion by the F plasmid
HW10_RS23700	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS23725	COG0668	transmembrane transport
HW10_RS23735	COG0745	RESPONSE REGULATOR receiver
HW10_RS23750	COG2096	Adenosyltransferase
HW10_RS23755	COG0494	nUDIX hydrolase
HW10_RS23780	COG0739	heme binding
HW10_RS23780	COG1196	nuclear chromosome segregation
HW10_RS23780	COG0741	lytic transglycosylase activity
HW10_RS23825	COG0772	Belongs to the SEDS family
HW10_RS23840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HW10_RS23880	COG3107	peptidoglycan biosynthetic process
HW10_RS23895	COG2823	Periplasmic or secreted lipoprotein
HW10_RS23900	COG2969	positive regulation of protein catabolic process
HW10_RS23905	COG0625	glutathione transferase activity
HW10_RS23910	COG2857	Cytochrome c1
HW10_RS23915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HW10_RS23920	COG0723	plastoquinol--plastocyanin reductase activity
HW10_RS23935	COG0667	Aldo Keto reductase
HW10_RS23940	COG1960	acyl-CoA dehydrogenase activity
HW10_RS23955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW10_RS23965	COG2945	thiolester hydrolase activity
HW10_RS23985	COG2951	lytic endotransglycosylase activity
HW10_RS23995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HW10_RS24035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HW10_RS24040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HW10_RS24045	COG1127	ABC transporter
HW10_RS24055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HW10_RS24070	COG1137	ATPase activity
HW10_RS24125	COG0312	modulator of DNA gyrase
HW10_RS24135	COG0312	modulator of DNA gyrase
HW10_RS24140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HW10_RS24150	COG1530	ribonuclease E activity
HW10_RS24165	COG1792	Involved in formation and maintenance of cell shape
HW10_RS24170	COG1077	Cell shape determining protein MreB Mrl
HW10_RS24190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HW10_RS24195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS24200	COG4676	Protein conserved in bacteria
HW10_RS24205	COG5445	Predicted secreted protein (DUF2300)
HW10_RS24220	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HW10_RS24225	COG4676	Protein conserved in bacteria
HW10_RS24230	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HW10_RS24245	COG0747	negative chemotaxis
HW10_RS24250	COG0747	negative chemotaxis
HW10_RS24265	COG0747	negative chemotaxis
HW10_RS24280	COG0747	negative chemotaxis
HW10_RS24285	COG0601	transmembrane transport
HW10_RS24290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HW10_RS24295	COG0444	Belongs to the ABC transporter superfamily
HW10_RS24300	COG4608	Belongs to the ABC transporter superfamily
HW10_RS24315	COG1984	allophanate hydrolase subunit 2
HW10_RS24335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HW10_RS24340	COG4774	siderophore transport
HW10_RS24355	COG2194	sulfuric ester hydrolase activity
HW10_RS24365	COG0019	diaminopimelate decarboxylase activity
HW10_RS24470	COG1252	NADH dehydrogenase
HW10_RS24475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW10_RS24490	COG1192	Involved in chromosome partitioning
HW10_RS24605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HW10_RS24620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW10_RS24645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW10_RS24770	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HW10_RS24820	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS24830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HW10_RS24835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW10_RS24845	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS25020	COG3609	addiction module antidote protein, CC2985 family
HW10_RS25055	COG2801	Transposase and inactivated derivatives
HW10_RS25085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HW10_RS25150	COG4969	Belongs to the N-Me-Phe pilin family
HW10_RS25190	COG1047	Peptidyl-prolyl cis-trans
HW10_RS25205	COG0196	riboflavin kinase activity
HW10_RS25220	COG3045	CreA protein
HW10_RS25245	COG0142	geranyltranstransferase activity
HW10_RS25260	COG0545	Peptidyl-prolyl cis-trans isomerase
HW10_RS25280	COG1067	ATP-dependent peptidase activity
HW10_RS25305	COG4650	regulator
HW10_RS25320	COG1690	Belongs to the RtcB family
HW10_RS25325	COG3541	Predicted nucleotidyltransferase
HW10_RS25345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HW10_RS25370	COG1136	(ABC) transporter
HW10_RS25370	COG0577	efflux transmembrane transporter activity
HW10_RS25375	COG1136	(ABC) transporter
HW10_RS25375	COG0577	efflux transmembrane transporter activity
HW10_RS25380	COG0488	(ABC) transporter
HW10_RS25400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW10_RS25405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS25430	COG0523	cobalamin synthesis protein
HW10_RS25435	COG2879	small protein
HW10_RS25440	COG1966	Carbon starvation protein
HW10_RS25510	COG3608	succinylglutamate desuccinylase aspartoacylase
HW10_RS25510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HW10_RS25515	COG2010	Cytochrome c
HW10_RS25555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HW10_RS25565	COG0833	amino acid
HW10_RS25570	COG2119	membrane
HW10_RS25585	COG0501	Belongs to the peptidase M48B family
HW10_RS25590	COG0840	transmembrane signaling receptor activity
HW10_RS25595	COG2135	peptidase activity
HW10_RS25600	COG1285	pathogenesis
HW10_RS25660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HW10_RS25715	COG1090	epimerase
HW10_RS25720	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HW10_RS25730	COG0789	Transcriptional regulator
HW10_RS25750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HW10_RS25805	COG0012	GTP binding
HW10_RS25820	COG3549	Plasmid maintenance system killer
HW10_RS25835	COG0288	reversible hydration of carbon dioxide
HW10_RS25845	COG0456	acetyltransferase
HW10_RS25890	COG1840	ABC-type Fe3 transport system, periplasmic component
HW10_RS25895	COG1178	ABC-type Fe3 transport system permease component
HW10_RS25900	COG3008	intermembrane lipid transfer
HW10_RS25905	COG2995	paraquat-inducible protein a
HW10_RS25910	COG2995	paraquat-inducible protein a
HW10_RS25950	COG1183	phosphatidylcholine synthase activity
HW10_RS25965	COG0028	Belongs to the TPP enzyme family
HW10_RS25975	COG3098	single-species biofilm formation
HW10_RS25985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HW10_RS26020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW10_RS26025	COG4558	Periplasmic binding protein
HW10_RS26030	COG3720	iron ion transport
HW10_RS26035	COG4771	TonB-dependent receptor
HW10_RS26060	COG0436	Aminotransferase
HW10_RS26070	COG2321	neutral zinc metallopeptidase
HW10_RS26095	COG0436	Aminotransferase
HW10_RS26100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW10_RS26115	COG4191	Histidine kinase
HW10_RS26220	COG0195	Participates in both transcription termination and antitermination
HW10_RS26255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HW10_RS26325	COG0497	DNA recombination
HW10_RS26355	COG2186	Transcriptional regulator
HW10_RS26360	COG1620	l-lactate permease
HW10_RS26410	COG0697	spore germination
HW10_RS26430	COG0697	spore germination
HW10_RS26435	COG1522	sequence-specific DNA binding
HW10_RS26445	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS26465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS26495	COG0509	glycine decarboxylation via glycine cleavage system
HW10_RS26535	COG0531	amino acid
HW10_RS26550	COG3276	selenocysteine insertion sequence binding
HW10_RS26565	COG2864	formate dehydrogenase
HW10_RS26570	COG0437	4 iron, 4 sulfur cluster binding
HW10_RS26580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HW10_RS26585	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS26585	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS26610	COG0463	Glycosyl transferase, family 2
HW10_RS26620	COG0534	Mate efflux family protein
HW10_RS26630	COG1283	sodium-dependent phosphate transmembrane transporter activity
HW10_RS26655	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HW10_RS26680	COG4221	oxidoreductase activity
HW10_RS26685	COG1272	protein, Hemolysin III
HW10_RS26720	COG0023	Translation Initiation Factor
HW10_RS26810	COG2095	MarC family integral membrane protein
HW10_RS26815	COG0683	leucine binding
HW10_RS26830	COG0411	ABC transporter
HW10_RS26875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW10_RS26890	COG0443	Heat shock 70 kDa protein
HW10_RS26915	COG0789	Transcriptional regulator
HW10_RS26920	COG2982	Protein involved in outer membrane biogenesis
HW10_RS26925	COG2193	ferroxidase activity
HW10_RS26935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HW10_RS26940	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HW10_RS27000	COG3712	iron ion homeostasis
HW10_RS27005	COG1595	DNA-templated transcription, initiation
HW10_RS27025	COG2814	Major facilitator Superfamily
HW10_RS27035	COG0583	DNA-binding transcription factor activity
HW10_RS27060	COG4221	oxidoreductase activity
HW10_RS27065	COG2423	ornithine cyclodeaminase activity
HW10_RS27095	COG0583	DNA-binding transcription factor activity
HW10_RS27110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HW10_RS27150	COG0668	transmembrane transport
HW10_RS27170	COG5001	Diguanylate cyclase
HW10_RS27170	COG3300	MHYT domain
HW10_RS27185	COG0305	Participates in initiation and elongation during chromosome replication
HW10_RS27215	COG0557	exoribonuclease II activity
HW10_RS27245	COG0330	HflC and HflK could
HW10_RS27250	COG0330	HflC and HflK could
HW10_RS27255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HW10_RS27275	COG0860	N-Acetylmuramoyl-L-alanine amidase
HW10_RS27280	COG0802	atpase or kinase
HW10_RS27285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HW10_RS27285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HW10_RS27340	COG3300	MHYT domain
HW10_RS27340	COG5001	Diguanylate cyclase
HW10_RS27345	COG3830	Belongs to the UPF0237 family
HW10_RS27345	COG0560	Phosphoserine phosphatase
HW10_RS27355	COG1988	membrane-bound metal-dependent
HW10_RS27370	COG3577	Aspartyl protease
HW10_RS27385	COG3150	esterase
HW10_RS27390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HW10_RS27400	COG0494	nUDIX hydrolase
HW10_RS27415	COG1538	Outer membrane efflux protein
HW10_RS27420	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW10_RS27435	COG0045	succinate-CoA ligase (ADP-forming) activity
HW10_RS27440	COG1960	acyl-CoA dehydrogenase activity
HW10_RS27445	COG1024	Enoyl-CoA hydratase
HW10_RS27450	COG0833	amino acid
HW10_RS27480	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS27480	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS27490	COG1519	Transferase
HW10_RS27495	COG0583	DNA-binding transcription factor activity
HW10_RS27510	COG0667	Aldo Keto reductase
HW10_RS27520	COG1960	acyl-CoA dehydrogenase activity
HW10_RS27525	COG1960	acyl-CoA dehydrogenase activity
HW10_RS27550	COG1215	transferase activity, transferring glycosyl groups
HW10_RS27570	COG0438	transferase activity, transferring glycosyl groups
HW10_RS27575	COG2192	nodulation
HW10_RS27600	COG0438	transferase activity, transferring glycosyl groups
HW10_RS27605	COG0859	PFAM glycosyl transferase family 9
HW10_RS27610	COG0859	PFAM glycosyl transferase family 9
HW10_RS27655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HW10_RS27660	COG1960	acyl-CoA dehydrogenase activity
HW10_RS27675	COG1196	nuclear chromosome segregation
HW10_RS27675	COG3264	Mechanosensitive ion channel
HW10_RS27685	COG0730	response to heat
HW10_RS27690	COG2873	o-acetylhomoserine
HW10_RS27710	COG0583	DNA-binding transcription factor activity
HW10_RS27715	COG2814	Major facilitator Superfamily
HW10_RS27740	COG0493	'glutamate synthase
HW10_RS27745	COG0067	glutamate synthase
HW10_RS27745	COG0069	glutamate synthase activity
HW10_RS27745	COG0070	glutamate synthase
HW10_RS27795	COG0281	malic enzyme
HW10_RS27815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HW10_RS27930	COG0840	transmembrane signaling receptor activity
HW10_RS27940	COG1126	abc transporter atp-binding protein
HW10_RS27945	COG0765	amino acid transport
HW10_RS27975	COG1051	belongs to the nudix hydrolase family
HW10_RS27980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW10_RS27985	COG0251	oxidation-reduction process
HW10_RS28030	COG2986	histidine ammonia-lyase
HW10_RS28035	COG4175	Glycine betaine
HW10_RS28040	COG4176	ABC-type proline glycine betaine transport system permease component
HW10_RS28060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HW10_RS28095	COG0402	S-adenosylhomocysteine deaminase activity
HW10_RS28145	COG0789	Transcriptional regulator
HW10_RS28150	COG1217	gtp-binding protein TYPA
HW10_RS28175	COG0668	transmembrane transport
HW10_RS28190	COG3852	Histidine kinase
HW10_RS28210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HW10_RS28240	COG4942	peptidase
HW10_RS28245	COG0793	Belongs to the peptidase S41A family
HW10_RS28250	COG2861	carbohydrate metabolic process
HW10_RS28310	COG0579	oxidoreductase
HW10_RS28320	COG1194	a g-specific adenine glycosylase
HW10_RS28330	COG0673	inositol 2-dehydrogenase activity
HW10_RS28340	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS28375	COG1846	Transcriptional regulator
HW10_RS28385	COG1566	PFAM secretion protein HlyD family protein
HW10_RS28390	COG2814	Major facilitator Superfamily
HW10_RS28400	COG1088	dTDP-glucose 4,6-dehydratase activity
HW10_RS28405	COG1091	dTDP-4-dehydrorhamnose reductase activity
HW10_RS28480	COG1218	3'(2'),5'-bisphosphate nucleotidase
HW10_RS28485	COG0494	nUDIX hydrolase
HW10_RS28490	COG1011	Hydrolase
HW10_RS28495	COG1652	LysM domain
HW10_RS28505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HW10_RS28525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HW10_RS28535	COG0824	Thioesterase
HW10_RS28540	COG1454	alcohol dehydrogenase
HW10_RS28545	COG1960	acyl-CoA dehydrogenase activity
HW10_RS28550	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW10_RS28550	COG1024	Enoyl-CoA hydratase
HW10_RS28560	COG0778	Nitroreductase
HW10_RS28590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HW10_RS28595	COG0189	ligase activity
HW10_RS28595	COG4067	protein conserved in archaea
HW10_RS28620	COG2183	response to ionizing radiation
HW10_RS28650	COG0306	phosphate transporter
HW10_RS28655	COG1392	Phosphate transport regulator
HW10_RS28660	COG3025	triphosphatase activity
HW10_RS28665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW10_RS28695	COG1178	ABC-type Fe3 transport system permease component
HW10_RS28705	COG0583	DNA-binding transcription factor activity
HW10_RS28720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW10_RS28730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW10_RS28735	COG0006	proline dipeptidase activity
HW10_RS28760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HW10_RS28770	COG0842	Transport permease protein
HW10_RS28775	COG1129	ABC transporter
HW10_RS28775	COG0842	Transport permease protein
HW10_RS28780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW10_RS28795	COG2271	Major facilitator Superfamily
HW10_RS28810	COG2755	lipolytic protein G-D-S-L family
HW10_RS28810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HW10_RS28840	COG0586	Pfam SNARE associated Golgi protein
HW10_RS28845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HW10_RS28850	COG2050	protein possibly involved in aromatic compounds catabolism
HW10_RS28860	COG0672	)-iron permease
HW10_RS28865	COG1280	lysine exporter protein (LysE YggA)
HW10_RS28870	COG0861	Integral membrane protein TerC family
HW10_RS28880	COG0488	(ABC) transporter
HW10_RS28935	COG3275	phosphorelay sensor kinase activity
HW10_RS28965	COG0598	Magnesium transport protein CorA
HW10_RS28995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HW10_RS29065	COG0432	Pfam Uncharacterised protein family UPF0047
HW10_RS29070	COG0004	ammonium transporteR
HW10_RS29075	COG0347	Belongs to the P(II) protein family
HW10_RS29085	COG0606	chelatase, subunit chli
HW10_RS29090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW10_RS29100	COG0583	DNA-binding transcription factor activity
HW10_RS29115	COG0210	DNA helicase
HW10_RS29120	COG0028	Belongs to the TPP enzyme family
HW10_RS29130	COG0427	acetyl-CoA hydrolase
HW10_RS29140	COG1396	sequence-specific DNA binding
HW10_RS29140	COG1917	Cupin 2, conserved barrel domain protein
HW10_RS29150	COG0251	oxidation-reduction process
HW10_RS29180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW10_RS29185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW10_RS29190	COG2814	Major facilitator Superfamily
HW10_RS29195	COG1012	belongs to the aldehyde dehydrogenase family
HW10_RS29200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HW10_RS29220	COG0747	negative chemotaxis
HW10_RS29235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HW10_RS29275	COG3245	cytochrome
HW10_RS29295	COG0708	Exodeoxyribonuclease III
HW10_RS29310	COG1561	YicC-like family, N-terminal region
HW10_RS29325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW10_RS29345	COG4753	response regulator
HW10_RS29345	COG2207	Transcriptional regulator
HW10_RS29355	COG0583	DNA-binding transcription factor activity
HW10_RS29360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HW10_RS29400	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HW10_RS29405	COG0247	lactate metabolic process
HW10_RS29410	COG0277	FAD linked oxidase domain protein
HW10_RS29415	COG0277	FAD linked oxidase domain protein
HW10_RS29420	COG2186	Transcriptional regulator
HW10_RS29450	COG1253	flavin adenine dinucleotide binding
HW10_RS29455	COG0739	heme binding
HW10_RS29515	COG0477	Major facilitator Superfamily
HW10_RS29520	COG1607	acyl-coa hydrolase
HW10_RS29545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW10_RS29550	COG4175	Glycine betaine
HW10_RS29555	COG4176	ABC-type proline glycine betaine transport system permease component
HW10_RS29565	COG1760	l-serine dehydratase
HW10_RS29580	COG0583	DNA-binding transcription factor activity
HW10_RS29590	COG0657	acetylesterase activity
HW10_RS29605	COG3246	L-lysine catabolic process to acetate
HW10_RS29660	COG1902	pentaerythritol trinitrate reductase activity
HW10_RS29660	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW10_RS29665	COG2181	nitrate reductase activity
HW10_RS29665	COG0247	lactate metabolic process
HW10_RS29685	COG3655	Transcriptional regulator
HW10_RS29725	COG1017	nitric oxide dioxygenase activity
HW10_RS29725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HW10_RS29815	COG0583	DNA-binding transcription factor activity
HW10_RS29830	COG2391	methyltransferase activity
HW10_RS29855	COG5016	pyruvate
HW10_RS29855	COG0511	ligase activity, forming carbon-carbon bonds
HW10_RS29860	COG0439	Biotin carboxylase
HW10_RS29865	COG0583	DNA-binding transcription factor activity
HW10_RS29880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HW10_RS29885	COG0826	peptidase U32
HW10_RS29905	COG0210	DNA helicase
HW10_RS29915	COG0427	acetyl-CoA hydrolase
HW10_RS29930	COG0438	transferase activity, transferring glycosyl groups
HW10_RS29975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW10_RS29980	COG2755	lipolytic protein G-D-S-L family
HW10_RS29980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HW10_RS30020	COG0679	Auxin Efflux Carrier
HW10_RS30030	COG2851	Citrate transporter
HW10_RS30035	COG0861	Integral membrane protein TerC family
HW10_RS30040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HW10_RS30045	COG1690	Belongs to the RtcB family
HW10_RS30090	COG0700	Nucleoside recognition
HW10_RS30095	COG1301	dicarboxylic acid transport
HW10_RS30120	COG5002	protein histidine kinase activity
HW10_RS30125	COG3023	N-Acetylmuramoyl-L-alanine amidase
HW10_RS30130	COG2095	MarC family integral membrane protein
HW10_RS30155	COG3245	cytochrome
HW10_RS30190	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HW10_RS30195	COG0735	belongs to the Fur family
HW10_RS30205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HW10_RS30220	COG2011	ABC-type metal ion transport system permease component
HW10_RS30250	COG0531	amino acid
HW10_RS30260	COG4191	Histidine kinase
HW10_RS30295	COG4651	solute:proton antiporter activity
HW10_RS30295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW10_RS30300	COG1607	acyl-coa hydrolase
HW10_RS30310	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS30315	COG0174	glutamine synthetase
HW10_RS30320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HW10_RS30325	COG1028	Short-chain dehydrogenase reductase Sdr
HW10_RS30350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW10_RS30350	COG4651	solute:proton antiporter activity
HW10_RS30355	COG0477	Major facilitator Superfamily
HW10_RS30365	COG0523	cobalamin synthesis protein
HW10_RS30395	COG0860	N-Acetylmuramoyl-L-alanine amidase
HW10_RS30410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HW10_RS30430	COG2358	TRAP transporter, solute receptor (TAXI family
HW10_RS30435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HW10_RS30455	COG1349	DNA-binding transcription factor activity
HW10_RS30515	COG1475	DNA binding
HW10_RS30520	COG1192	Involved in chromosome partitioning