locus-tag	class	description
I5102_RS00015	COG0679	Auxin Efflux Carrier
I5102_RS00025	COG2851	Citrate transporter
I5102_RS00030	COG0861	Integral membrane protein TerC family
I5102_RS00035	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
I5102_RS00040	COG1690	Belongs to the RtcB family
I5102_RS00075	COG0700	Nucleoside recognition
I5102_RS00080	COG1301	dicarboxylic acid transport
I5102_RS00100	COG5002	protein histidine kinase activity
I5102_RS00105	COG3023	N-Acetylmuramoyl-L-alanine amidase
I5102_RS00110	COG2095	MarC family integral membrane protein
I5102_RS00135	COG3245	cytochrome
I5102_RS00170	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
I5102_RS00175	COG0735	belongs to the Fur family
I5102_RS00185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5102_RS00200	COG2011	ABC-type metal ion transport system permease component
I5102_RS00230	COG0531	amino acid
I5102_RS00240	COG4191	Histidine kinase
I5102_RS00275	COG4651	solute:proton antiporter activity
I5102_RS00275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I5102_RS00280	COG1607	acyl-coa hydrolase
I5102_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS00295	COG0174	glutamine synthetase
I5102_RS00300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I5102_RS00305	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS00330	COG4651	solute:proton antiporter activity
I5102_RS00330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I5102_RS00335	COG0477	Major facilitator Superfamily
I5102_RS00345	COG0523	cobalamin synthesis protein
I5102_RS00390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I5102_RS00410	COG2358	TRAP transporter, solute receptor (TAXI family
I5102_RS00415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I5102_RS00470	COG1349	DNA-binding transcription factor activity
I5102_RS00530	COG1475	DNA binding
I5102_RS00535	COG1192	Involved in chromosome partitioning
I5102_RS00605	COG2010	Cytochrome c
I5102_RS00620	COG2818	Glycosylase
I5102_RS00635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I5102_RS00650	COG0569	domain protein
I5102_RS00670	COG1652	LysM domain
I5102_RS00675	COG0758	DNA mediated transformation
I5102_RS00705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5102_RS00725	COG3119	arylsulfatase activity
I5102_RS00730	COG0583	DNA-binding transcription factor activity
I5102_RS00765	COG3360	Dodecin
I5102_RS00810	COG3174	membrane
I5102_RS00855	COG0367	asparagine synthase
I5102_RS00875	COG0583	DNA-binding transcription factor activity
I5102_RS00890	COG1764	response to oxidative stress
I5102_RS00925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I5102_RS00930	COG0339	signal peptide processing
I5102_RS00935	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
I5102_RS00950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
I5102_RS00965	COG2815	serine threonine protein kinase
I5102_RS00965	COG0515	serine threonine protein kinase
I5102_RS00970	COG0631	protein serine/threonine phosphatase activity
I5102_RS00985	COG1360	Flagellar Motor Protein
I5102_RS01110	COG0659	secondary active sulfate transmembrane transporter activity
I5102_RS01120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I5102_RS01125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I5102_RS01130	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
I5102_RS01170	COG2153	protein acetylation
I5102_RS01210	COG0583	DNA-binding transcription factor activity
I5102_RS01235	COG2824	Alkylphosphonate utilization operon protein PhnA
I5102_RS01265	COG0402	S-adenosylhomocysteine deaminase activity
I5102_RS01270	COG3845	ABC transporter
I5102_RS01275	COG4603	Belongs to the binding-protein-dependent transport system permease family
I5102_RS01280	COG1079	Belongs to the binding-protein-dependent transport system permease family
I5102_RS01350	COG0583	DNA-binding transcription factor activity
I5102_RS01355	COG3485	protocatechuate 3,4-dioxygenase
I5102_RS01360	COG3485	protocatechuate 3,4-dioxygenase
I5102_RS01365	COG1414	Transcriptional regulator
I5102_RS01380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS01385	COG0583	DNA-binding transcription factor activity
I5102_RS01415	COG2233	PERMEase
I5102_RS01420	COG1309	transcriptional regulator
I5102_RS01455	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
I5102_RS01470	COG0835	chemotaxis
I5102_RS01475	COG0643	Histidine kinase
I5102_RS01475	COG2198	Histidine kinase
I5102_RS01480	COG0745	RESPONSE REGULATOR receiver
I5102_RS01490	COG0583	DNA-binding transcription factor activity
I5102_RS01495	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS01505	COG1116	anion transmembrane transporter activity
I5102_RS01510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS01515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS01555	COG2175	clavaminate synthase activity
I5102_RS01600	COG0154	amidase activity
I5102_RS01610	COG1177	transmembrane transport
I5102_RS01615	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5102_RS01625	COG0583	DNA-binding transcription factor activity
I5102_RS01660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I5102_RS01690	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS01695	COG1113	amino acid transport
I5102_RS01710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I5102_RS01720	COG1396	sequence-specific DNA binding
I5102_RS01725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I5102_RS01730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I5102_RS01740	COG0477	Major facilitator Superfamily
I5102_RS01750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I5102_RS01755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5102_RS01760	COG0583	DNA-binding transcription factor activity
I5102_RS01780	COG0673	inositol 2-dehydrogenase activity
I5102_RS01800	COG2271	Major facilitator Superfamily
I5102_RS01810	COG1309	transcriptional regulator
I5102_RS01815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I5102_RS01825	COG0477	Major facilitator Superfamily
I5102_RS01845	COG2239	Acts as a magnesium transporter
I5102_RS01925	COG0745	RESPONSE REGULATOR receiver
I5102_RS01935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5102_RS01950	COG0583	DNA-binding transcription factor activity
I5102_RS01955	COG2807	transmembrane transport
I5102_RS01975	COG0501	Belongs to the peptidase M48B family
I5102_RS01995	COG4208	sulfate ABC transporter
I5102_RS02005	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
I5102_RS02040	COG2199	diguanylate cyclase activity
I5102_RS02065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I5102_RS02070	COG0174	glutamine synthetase
I5102_RS02075	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
I5102_RS02080	COG0174	glutamine synthetase
I5102_RS02100	COG3842	ATPase activity
I5102_RS02105	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5102_RS02110	COG1177	transmembrane transport
I5102_RS02160	COG0765	amino acid transport
I5102_RS02175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5102_RS02180	COG0277	FAD linked oxidase domain protein
I5102_RS02185	COG0179	Fumarylacetoacetate (FAA) hydrolase
I5102_RS02195	COG3111	PFAM Bacterial OB fold (BOF) protein
I5102_RS02205	COG0531	amino acid
I5102_RS02210	COG2182	Extracellular solute-binding protein
I5102_RS02215	COG1177	transmembrane transport
I5102_RS02225	COG3842	ATPase activity
I5102_RS02230	COG3204	pilus organization
I5102_RS02235	COG2234	aminopeptidase activity
I5102_RS02255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I5102_RS02265	COG0702	epimerase
I5102_RS02305	COG0730	response to heat
I5102_RS02340	COG0584	glycerophosphoryl diester phosphodiesterase
I5102_RS02360	COG0622	Phosphoesterase
I5102_RS02365	COG2233	PERMEase
I5102_RS02380	COG0693	protein deglycase activity
I5102_RS02415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5102_RS02425	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
I5102_RS02450	COG0429	hydrolase of the alpha beta-hydrolase fold
I5102_RS02460	COG0742	ribosomal rna small subunit methyltransferase
I5102_RS02465	COG0612	Peptidase, M16
I5102_RS02470	COG0612	Peptidase, M16
I5102_RS02475	COG0552	protein localization to endoplasmic reticulum
I5102_RS02480	COG2884	Cell division ATP-binding protein ftsE
I5102_RS02485	COG2177	Part of the ABC transporter FtsEX involved in
I5102_RS02505	COG2363	Small membrane protein
I5102_RS02540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I5102_RS02555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I5102_RS02555	COG2813	Specifically methylates the guanine in position
I5102_RS02565	COG1160	GTP binding
I5102_RS02570	COG1872	DUF167
I5102_RS02615	COG0626	cystathionine gamma-synthase activity
I5102_RS02710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I5102_RS02725	COG3038	cytochrome b561
I5102_RS02755	COG0513	Belongs to the DEAD box helicase family
I5102_RS02765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
I5102_RS02770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I5102_RS02795	COG1309	transcriptional regulator
I5102_RS02800	COG0402	S-adenosylhomocysteine deaminase activity
I5102_RS02805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I5102_RS02815	COG0493	'glutamate synthase
I5102_RS02825	COG1953	Uracil, thiamine, allantoin
I5102_RS02840	COG1960	acyl-CoA dehydrogenase activity
I5102_RS02845	COG0583	DNA-binding transcription factor activity
I5102_RS02855	COG0306	phosphate transporter
I5102_RS02865	COG0330	HflC and HflK could
I5102_RS02875	COG1289	transmembrane transporter activity
I5102_RS02880	COG0513	Belongs to the DEAD box helicase family
I5102_RS02890	COG0189	ligase activity
I5102_RS02890	COG4067	protein conserved in archaea
I5102_RS02900	COG0477	Major facilitator Superfamily
I5102_RS02905	COG0542	response to heat
I5102_RS02915	COG0204	Acyl-transferase
I5102_RS02925	COG0745	RESPONSE REGULATOR receiver
I5102_RS02930	COG2205	protein histidine kinase activity
I5102_RS02935	COG4452	Inner membrane protein CreD
I5102_RS02965	COG4774	siderophore transport
I5102_RS02970	COG3712	iron ion homeostasis
I5102_RS02975	COG1595	DNA-templated transcription, initiation
I5102_RS02980	COG0625	glutathione transferase activity
I5102_RS02990	COG1309	transcriptional regulator
I5102_RS02995	COG1953	Uracil, thiamine, allantoin
I5102_RS03015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I5102_RS03050	COG3585	molybdate ion transport
I5102_RS03050	COG2005	Transcriptional regulator
I5102_RS03055	COG5544	Lipoprotein
I5102_RS03060	COG1040	competence protein
I5102_RS03080	COG0511	ligase activity, forming carbon-carbon bonds
I5102_RS03095	COG1984	allophanate hydrolase subunit 2
I5102_RS03105	COG3121	Chaperone
I5102_RS03120	COG2226	methyltransferase
I5102_RS03120	COG1073	alpha beta
I5102_RS03140	COG1960	acyl-CoA dehydrogenase activity
I5102_RS03145	COG1960	acyl-CoA dehydrogenase activity
I5102_RS03150	COG1960	acyl-CoA dehydrogenase activity
I5102_RS03160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I5102_RS03160	COG1648	precorrin-2 dehydrogenase activity
I5102_RS03250	COG0583	DNA-binding transcription factor activity
I5102_RS03255	COG2258	MOSC domain
I5102_RS03265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I5102_RS03285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS03295	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
I5102_RS03350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5102_RS03355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I5102_RS03365	COG3622	Belongs to the hyi family
I5102_RS03370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I5102_RS03410	COG2081	HI0933 family
I5102_RS03415	COG1451	nucleotide metabolic process
I5102_RS03420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I5102_RS03425	COG3152	Membrane
I5102_RS03430	COG4977	sequence-specific DNA binding
I5102_RS03430	COG1917	Cupin 2, conserved barrel domain protein
I5102_RS03435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5102_RS03535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I5102_RS03555	COG2719	SpoVR family
I5102_RS03565	COG2766	serine protein kinase
I5102_RS03615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
I5102_RS03630	COG2197	response regulator
I5102_RS03640	COG3842	ATPase activity
I5102_RS03650	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5102_RS03660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I5102_RS03685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5102_RS03700	COG3179	chitinase
I5102_RS03800	COG1765	OsmC-like protein
I5102_RS03815	COG0537	adenosine 5'-monophosphoramidase activity
I5102_RS03825	COG0300	oxidoreductase activity
I5102_RS03840	COG1981	membrane
I5102_RS03870	COG0739	heme binding
I5102_RS04035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
I5102_RS04160	COG2814	Major facilitator Superfamily
I5102_RS04185	COG1021	2,3-dihydroxybenzoate-AMP ligase
I5102_RS04195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5102_RS04195	COG3433	isochorismatase activity
I5102_RS04195	COG2226	methyltransferase
I5102_RS04200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5102_RS04200	COG3433	isochorismatase activity
I5102_RS04200	COG2226	methyltransferase
I5102_RS04210	COG1132	(ABC) transporter
I5102_RS04210	COG2375	cellular response to nickel ion
I5102_RS04290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS04305	COG2706	6-phosphogluconolactonase activity
I5102_RS04325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5102_RS04330	COG1960	acyl-CoA dehydrogenase activity
I5102_RS04340	COG4191	Histidine kinase
I5102_RS04345	COG4566	intracellular signal transduction
I5102_RS04350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS04355	COG0765	amino acid transport
I5102_RS04360	COG0765	amino acid transport
I5102_RS04380	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS04385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I5102_RS04390	COG2271	Major facilitator Superfamily
I5102_RS04435	COG2226	methyltransferase
I5102_RS04445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5102_RS04460	COG0251	oxidation-reduction process
I5102_RS04470	COG0693	protein deglycase activity
I5102_RS04475	COG0492	ferredoxin-NADP+ reductase activity
I5102_RS04480	COG1959	2 iron, 2 sulfur cluster binding
I5102_RS04510	COG0154	amidase activity
I5102_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS04520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5102_RS04525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5102_RS04530	COG4592	Periplasmic binding protein
I5102_RS04535	COG1120	ATPase activity
I5102_RS04545	COG4774	siderophore transport
I5102_RS04545	COG1629	transport
I5102_RS04550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5102_RS04555	COG4991	sh3 domain protein
I5102_RS04560	COG1063	alcohol dehydrogenase
I5102_RS04570	COG0022	dehydrogenase e1 component
I5102_RS04575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I5102_RS04580	COG3199	ATP-NAD kinase
I5102_RS04590	COG3284	Transcriptional regulator
I5102_RS04615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS04645	COG2814	Major facilitator Superfamily
I5102_RS04650	COG1846	Transcriptional regulator
I5102_RS04660	COG3278	Belongs to the heme-copper respiratory oxidase family
I5102_RS04665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5102_RS04675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5102_RS04690	COG3971	2-oxopent-4-enoate hydratase activity
I5102_RS04695	COG2271	Major facilitator Superfamily
I5102_RS04705	COG3384	dioxygenase
I5102_RS04710	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS04750	COG1611	Belongs to the LOG family
I5102_RS04805	COG2259	Doxx family
I5102_RS04815	COG2205	protein histidine kinase activity
I5102_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS04845	COG1063	alcohol dehydrogenase
I5102_RS04850	COG2271	Major facilitator Superfamily
I5102_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS04905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I5102_RS04920	COG3121	Chaperone
I5102_RS04925	COG3188	usher protein
I5102_RS04935	COG3210	domain, Protein
I5102_RS04945	COG2197	response regulator
I5102_RS04985	COG0531	amino acid
I5102_RS05005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5102_RS05015	COG3047	cAMP biosynthetic process
I5102_RS05045	COG3118	belongs to the thioredoxin family
I5102_RS05050	COG2264	protein methyltransferase activity
I5102_RS05065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I5102_RS05065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I5102_RS05090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I5102_RS05095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I5102_RS05105	COG3577	Aspartyl protease
I5102_RS05130	COG0142	geranyltranstransferase activity
I5102_RS05140	COG4948	Mandelate Racemase Muconate Lactonizing
I5102_RS05160	COG1131	(ABC) transporter
I5102_RS05165	COG5002	protein histidine kinase activity
I5102_RS05185	COG0745	RESPONSE REGULATOR receiver
I5102_RS05195	COG3228	Belongs to the MtfA family
I5102_RS05200	COG0586	Pfam SNARE associated Golgi protein
I5102_RS05215	COG0456	acetyltransferase
I5102_RS05225	COG4303	Ethanolamine ammonia lyase large subunit
I5102_RS05230	COG0531	amino acid
I5102_RS05240	COG3284	Transcriptional regulator
I5102_RS05245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I5102_RS05260	COG0702	epimerase
I5102_RS05280	COG1346	cytolysis
I5102_RS05290	COG0586	Pfam SNARE associated Golgi protein
I5102_RS05330	COG0768	penicillin binding
I5102_RS05335	COG0772	Belongs to the SEDS family
I5102_RS05340	COG2951	lytic endotransglycosylase activity
I5102_RS05350	COG1686	Belongs to the peptidase S11 family
I5102_RS05380	COG2951	lytic endotransglycosylase activity
I5102_RS05415	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I5102_RS05425	COG4535	Mg2 and Co2 transporter CorC
I5102_RS05435	COG1702	phosphate starvation-inducible protein PhoH
I5102_RS05465	COG0351	phosphomethylpyrimidine kinase
I5102_RS05470	COG2205	protein histidine kinase activity
I5102_RS05470	COG2198	Histidine kinase
I5102_RS05470	COG0784	Response regulator, receiver
I5102_RS05480	COG1960	acyl-CoA dehydrogenase activity
I5102_RS05490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I5102_RS05530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I5102_RS05540	COG1643	Atp-dependent helicase
I5102_RS05585	COG3416	Protein conserved in bacteria
I5102_RS05595	COG0513	Belongs to the DEAD box helicase family
I5102_RS05605	COG2197	response regulator
I5102_RS05610	COG2200	EAL domain
I5102_RS05610	COG2202	Pas domain
I5102_RS05610	COG2199	diguanylate cyclase activity
I5102_RS05615	COG2205	protein histidine kinase activity
I5102_RS05615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS05635	COG1946	Acyl-CoA thioesterase
I5102_RS05655	COG4521	taurine ABC transporter
I5102_RS05665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS05670	COG2175	clavaminate synthase activity
I5102_RS05675	COG1297	OPT oligopeptide transporter protein
I5102_RS05680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5102_RS05695	COG1271	oxidase subunit
I5102_RS05700	COG1294	oxidase, subunit
I5102_RS05710	COG2207	Transcriptional regulator
I5102_RS05720	COG0183	Belongs to the thiolase family
I5102_RS05725	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS05750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
I5102_RS05760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I5102_RS05770	COG0521	Mo-molybdopterin cofactor biosynthetic process
I5102_RS05775	COG0303	'Molybdopterin
I5102_RS05780	COG0826	peptidase U32
I5102_RS05785	COG0826	peptidase U32
I5102_RS05790	COG3154	lipid carrier protein
I5102_RS05840	COG4772	TonB-dependent receptor
I5102_RS05845	COG3712	iron ion homeostasis
I5102_RS05850	COG1595	DNA-templated transcription, initiation
I5102_RS05860	COG0697	spore germination
I5102_RS05870	COG0583	DNA-binding transcription factor activity
I5102_RS05890	COG1566	PFAM secretion protein HlyD family protein
I5102_RS05940	COG0300	oxidoreductase activity
I5102_RS05945	COG2226	methyltransferase
I5102_RS05960	COG2197	response regulator
I5102_RS05965	COG3850	Histidine kinase
I5102_RS05975	COG2223	nitrite transmembrane transporter activity
I5102_RS05980	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I5102_RS05985	COG1140	nitrate reductase beta subunit
I5102_RS05990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I5102_RS05995	COG2181	nitrate reductase activity
I5102_RS06000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5102_RS06010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS06035	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS06045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS06110	COG0583	DNA-binding transcription factor activity
I5102_RS06140	COG0490	domain, Protein
I5102_RS06140	COG0471	metal ion transport
I5102_RS06145	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
I5102_RS06150	COG4120	Belongs to the binding-protein-dependent transport system permease family
I5102_RS06195	COG0795	lipopolysaccharide-transporting ATPase activity
I5102_RS06200	COG0795	lipopolysaccharide-transporting ATPase activity
I5102_RS06210	COG2200	EAL domain
I5102_RS06230	COG1862	Preprotein translocase
I5102_RS06245	COG3134	Outer membrane lipoprotein
I5102_RS06260	COG1045	serine acetyltransferase
I5102_RS06350	COG0436	Aminotransferase
I5102_RS06365	COG0667	Aldo Keto reductase
I5102_RS06405	COG0739	heme binding
I5102_RS06415	COG2847	Copper chaperone PCu(A)C
I5102_RS06425	COG1335	isochorismatase
I5102_RS06440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I5102_RS06450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I5102_RS06455	COG0583	DNA-binding transcription factor activity
I5102_RS06525	COG2130	NADP-dependent
I5102_RS06530	COG2132	Multicopper oxidase
I5102_RS06535	COG0590	tRNA wobble adenosine to inosine editing
I5102_RS06580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I5102_RS06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I5102_RS06585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I5102_RS06590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I5102_RS06595	COG2188	Transcriptional regulator
I5102_RS06635	COG0477	Major facilitator Superfamily
I5102_RS06640	COG4536	flavin adenine dinucleotide binding
I5102_RS06650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I5102_RS06675	COG1607	acyl-coa hydrolase
I5102_RS06695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I5102_RS06720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
I5102_RS06760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I5102_RS06770	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS06815	COG2197	response regulator
I5102_RS06820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I5102_RS06840	COG0477	Major facilitator Superfamily
I5102_RS06875	COG5001	Diguanylate cyclase
I5102_RS06875	COG3706	GGDEF domain
I5102_RS06875	COG4251	negative regulation of phosphorylation
I5102_RS06875	COG2203	Gaf domain
I5102_RS06910	COG3064	Membrane
I5102_RS06910	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
I5102_RS06910	COG1073	alpha beta
I5102_RS06925	COG2885	chlorophyll binding
I5102_RS06940	COG0789	Transcriptional regulator
I5102_RS06960	COG1214	PFAM Peptidase M22, glycoprotease
I5102_RS06970	COG1801	Protein of unknown function DUF72
I5102_RS06975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
I5102_RS07000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS07045	COG2166	iron-sulfur cluster assembly
I5102_RS07065	COG1393	Belongs to the ArsC family
I5102_RS07085	COG0025	NhaP-type Na H and K H
I5102_RS07090	COG0436	Aminotransferase
I5102_RS07100	COG0024	Methionine aminopeptidase
I5102_RS07180	COG1115	amino acid carrier protein
I5102_RS07230	COG2391	methyltransferase activity
I5102_RS07235	COG0583	DNA-binding transcription factor activity
I5102_RS07240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
I5102_RS07245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
I5102_RS07295	COG1546	Belongs to the CinA family
I5102_RS07315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
I5102_RS07320	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
I5102_RS07325	COG3530	Putative quorum-sensing-regulated virulence factor
I5102_RS07340	COG1177	transmembrane transport
I5102_RS07345	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5102_RS07355	COG3148	PFAM DTW domain containing protein
I5102_RS07375	COG0069	glutamate synthase activity
I5102_RS07400	COG0531	amino acid
I5102_RS07405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5102_RS07405	COG2169	Transcriptional regulator
I5102_RS07410	COG0477	Major facilitator Superfamily
I5102_RS07415	COG0583	DNA-binding transcription factor activity
I5102_RS07420	COG1960	acyl-CoA dehydrogenase activity
I5102_RS07425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
I5102_RS07430	COG1024	Enoyl-CoA hydratase
I5102_RS07435	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5102_RS07440	COG0183	Belongs to the thiolase family
I5102_RS07450	COG0583	DNA-binding transcription factor activity
I5102_RS07485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I5102_RS07525	COG2814	Major facilitator Superfamily
I5102_RS07565	COG0583	DNA-binding transcription factor activity
I5102_RS07580	COG0084	hydrolase, TatD family'
I5102_RS07585	COG1609	Transcriptional regulator
I5102_RS07595	COG1105	Belongs to the carbohydrate kinase PfkB family
I5102_RS07600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5102_RS07600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I5102_RS07600	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I5102_RS07710	COG3842	ATPase activity
I5102_RS07730	COG0243	molybdopterin cofactor binding
I5102_RS07735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
I5102_RS07740	COG2223	nitrite transmembrane transporter activity
I5102_RS07755	COG0450	alkyl hydroperoxide reductase
I5102_RS07785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS07825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I5102_RS07830	COG2264	protein methyltransferase activity
I5102_RS07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I5102_RS07895	COG0489	protein tyrosine kinase activity
I5102_RS07940	COG0791	NLP P60 protein
I5102_RS07955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I5102_RS07960	COG0668	transmembrane transport
I5102_RS07965	COG0477	Major facilitator Superfamily
I5102_RS07970	COG0513	Belongs to the DEAD box helicase family
I5102_RS07990	COG5002	protein histidine kinase activity
I5102_RS07990	COG0784	Response regulator, receiver
I5102_RS07990	COG2205	protein histidine kinase activity
I5102_RS07995	COG1363	Peptidase, m42
I5102_RS08000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I5102_RS08000	COG0189	ligase activity
I5102_RS08005	COG0367	asparagine synthase
I5102_RS08035	COG0183	Belongs to the thiolase family
I5102_RS08055	COG0450	alkyl hydroperoxide reductase
I5102_RS08060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS08065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS08075	COG0431	NADPH-dependent FMN reductase
I5102_RS08080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS08090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS08115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I5102_RS08140	COG0583	DNA-binding transcription factor activity
I5102_RS08145	COG1380	Effector of murein hydrolase LrgA
I5102_RS08150	COG1346	cytolysis
I5102_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS08175	COG1024	Enoyl-CoA hydratase
I5102_RS08185	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I5102_RS08230	COG0508	dehydrogenase complex catalyzes the overall conversion of
I5102_RS08270	COG1629	transport
I5102_RS08325	COG0583	DNA-binding transcription factor activity
I5102_RS08400	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
I5102_RS08405	COG3639	organic phosphonate transmembrane transporter activity
I5102_RS08410	COG2188	Transcriptional regulator
I5102_RS08415	COG3624	Phosphonate C-P lyase system protein PhnG
I5102_RS08425	COG3626	phosphonate metabolism
I5102_RS08430	COG3627	carbon phosphorus lyase activity
I5102_RS08435	COG4107	phosphonate C-P lyase system protein PhnK
I5102_RS08440	COG4778	phosphonate C-P lyase system protein PhnL
I5102_RS08445	COG3454	Phosphonate metabolism
I5102_RS08455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I5102_RS08530	COG0697	spore germination
I5102_RS08555	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
I5102_RS08575	COG0784	Response regulator, receiver
I5102_RS08575	COG0835	chemotaxis
I5102_RS08590	COG0745	RESPONSE REGULATOR receiver
I5102_RS08600	COG0514	ATP-dependent DNA helicase (RecQ)
I5102_RS08605	COG4251	negative regulation of phosphorylation
I5102_RS08605	COG3706	GGDEF domain
I5102_RS08605	COG2203	Gaf domain
I5102_RS08605	COG5001	Diguanylate cyclase
I5102_RS08625	COG1752	Esterase of the alpha-beta hydrolase superfamily
I5102_RS08665	COG2124	cytochrome p450
I5102_RS08670	COG4221	oxidoreductase activity
I5102_RS08715	COG0583	DNA-binding transcription factor activity
I5102_RS08745	COG3639	organic phosphonate transmembrane transporter activity
I5102_RS08755	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
I5102_RS08760	COG2084	Dehydrogenase
I5102_RS08775	COG0589	response to stress
I5102_RS08815	COG2814	Major facilitator Superfamily
I5102_RS08820	COG2030	dehydratase
I5102_RS08825	COG2267	carboxylic ester hydrolase activity
I5102_RS08830	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS08835	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS08845	COG1643	Atp-dependent helicase
I5102_RS08855	COG0537	adenosine 5'-monophosphoramidase activity
I5102_RS08910	COG1595	DNA-templated transcription, initiation
I5102_RS08980	COG1201	RNA secondary structure unwinding
I5102_RS08985	COG0784	Response regulator, receiver
I5102_RS08985	COG2205	protein histidine kinase activity
I5102_RS09000	COG4772	TonB-dependent receptor
I5102_RS09015	COG2076	Multidrug Resistance protein
I5102_RS09020	COG0385	Bile acid
I5102_RS09080	COG0604	alcohol dehydrogenase
I5102_RS09080	COG3321	synthase
I5102_RS09085	COG0560	Phosphoserine phosphatase
I5102_RS09100	COG1176	ABC-type spermidine putrescine transport system, permease component I
I5102_RS09130	COG0564	pseudouridine synthase activity
I5102_RS09140	COG2894	cell division
I5102_RS09150	COG1560	Kdo2-lipid A biosynthetic process
I5102_RS09165	COG2853	Lipoprotein
I5102_RS09185	COG3162	membrane
I5102_RS09190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5102_RS09220	COG1132	(ABC) transporter
I5102_RS09255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I5102_RS09270	COG0438	transferase activity, transferring glycosyl groups
I5102_RS09270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I5102_RS09300	COG1127	ABC transporter
I5102_RS09305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I5102_RS09310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I5102_RS09315	COG0727	PFAM Uncharacterised protein family (UPF0153)
I5102_RS09320	COG0778	Nitroreductase
I5102_RS09340	COG0745	RESPONSE REGULATOR receiver
I5102_RS09350	COG2350	Protein conserved in bacteria
I5102_RS09360	COG0613	PHP domain protein
I5102_RS09365	COG0009	L-threonylcarbamoyladenylate synthase
I5102_RS09370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
I5102_RS09375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I5102_RS09425	COG1175	transmembrane transport
I5102_RS09430	COG0395	ABC-type sugar transport system, permease component
I5102_RS09435	COG3842	ATPase activity
I5102_RS09445	COG0676	glucose-6-phosphate 1-epimerase activity
I5102_RS09490	COG0786	glutamate:sodium symporter activity
I5102_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS09520	COG0402	S-adenosylhomocysteine deaminase activity
I5102_RS09550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I5102_RS09580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
I5102_RS09600	COG0367	asparagine synthase
I5102_RS09605	COG0438	transferase activity, transferring glycosyl groups
I5102_RS09610	COG0438	transferase activity, transferring glycosyl groups
I5102_RS09620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I5102_RS09660	COG0583	DNA-binding transcription factor activity
I5102_RS09695	COG0596	Alpha beta hydrolase
I5102_RS09700	COG0800	Aldolase
I5102_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS09735	COG0583	DNA-binding transcription factor activity
I5102_RS09740	COG0251	oxidation-reduction process
I5102_RS09760	COG2226	methyltransferase
I5102_RS09800	COG0285	dihydrofolate synthase activity
I5102_RS09805	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I5102_RS09810	COG1286	toxin biosynthetic process
I5102_RS09910	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS09910	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5102_RS09935	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
I5102_RS09945	COG3139	Protein of unknown function (DUF1315)
I5102_RS09955	COG0308	aminopeptidase N
I5102_RS09985	COG0745	RESPONSE REGULATOR receiver
I5102_RS10020	COG0714	Associated with various cellular activities
I5102_RS10040	COG1335	isochorismatase
I5102_RS10050	COG2342	PFAM TM1410 hypothetical-related protein
I5102_RS10075	COG0297	glycogen (starch) synthase activity
I5102_RS10125	COG3130	regulation of translation
I5102_RS10135	COG2027	D-alanyl-D-alanine carboxypeptidase
I5102_RS10140	COG3171	Protein conserved in bacteria
I5102_RS10145	COG2197	response regulator
I5102_RS10150	COG2205	protein histidine kinase activity
I5102_RS10150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS10175	COG0004	ammonium transporteR
I5102_RS10185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5102_RS10195	COG0625	glutathione transferase activity
I5102_RS10200	COG1309	transcriptional regulator
I5102_RS10230	COG0521	Mo-molybdopterin cofactor biosynthetic process
I5102_RS10250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I5102_RS10255	COG1070	Carbohydrate kinase
I5102_RS10275	COG0741	lytic transglycosylase activity
I5102_RS10280	COG0488	(ABC) transporter
I5102_RS10290	COG0589	response to stress
I5102_RS10365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I5102_RS10375	COG1113	amino acid transport
I5102_RS10410	COG1477	protein flavinylation
I5102_RS10425	COG0584	glycerophosphoryl diester phosphodiesterase
I5102_RS10440	COG4591	ABC-type transport system involved in lipoprotein release permease component
I5102_RS10460	COG2333	competence protein COMEC
I5102_RS10460	COG0658	competence protein
I5102_RS10465	COG0811	peptide transport
I5102_RS10470	COG0848	biopolymer transport protein
I5102_RS10490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I5102_RS10500	COG1530	ribonuclease E activity
I5102_RS10510	COG0546	phosphoglycolate phosphatase activity
I5102_RS10515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
I5102_RS10515	COG0616	signal peptide processing
I5102_RS10525	COG1399	metal-binding, possibly nucleic acid-binding protein
I5102_RS10555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5102_RS10565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I5102_RS10585	COG0084	hydrolase, TatD family'
I5102_RS10670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I5102_RS10685	COG0183	Belongs to the thiolase family
I5102_RS10695	COG2233	PERMEase
I5102_RS10705	COG3038	cytochrome b561
I5102_RS10715	COG2814	Major facilitator Superfamily
I5102_RS10720	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS10725	COG1309	transcriptional regulator
I5102_RS10760	COG4160	amino acid transport
I5102_RS10765	COG4215	(ABC) transporter
I5102_RS10770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS10775	COG1473	amidohydrolase
I5102_RS10780	COG0583	DNA-binding transcription factor activity
I5102_RS10785	COG0840	transmembrane signaling receptor activity
I5102_RS10815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5102_RS10825	COG1120	ATPase activity
I5102_RS10855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5102_RS10885	COG3047	cAMP biosynthetic process
I5102_RS10885	COG2885	chlorophyll binding
I5102_RS10890	COG2197	response regulator
I5102_RS10900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5102_RS10905	COG1595	DNA-templated transcription, initiation
I5102_RS10920	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS10935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
I5102_RS10940	COG1960	acyl-CoA dehydrogenase activity
I5102_RS10945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I5102_RS10960	COG1309	transcriptional regulator
I5102_RS10990	COG0583	DNA-binding transcription factor activity
I5102_RS11000	COG0583	DNA-binding transcription factor activity
I5102_RS11010	COG0714	Associated with various cellular activities
I5102_RS11060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
I5102_RS11065	COG2259	Doxx family
I5102_RS11080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I5102_RS11095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
I5102_RS11100	COG4181	ATPase activity
I5102_RS11140	COG1764	response to oxidative stress
I5102_RS11145	COG1846	Transcriptional regulator
I5102_RS11150	COG0583	DNA-binding transcription factor activity
I5102_RS11160	COG0583	DNA-binding transcription factor activity
I5102_RS11170	COG3214	Protein conserved in bacteria
I5102_RS11175	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
I5102_RS11185	COG1024	Enoyl-CoA hydratase
I5102_RS11195	COG3384	dioxygenase
I5102_RS11235	COG2866	Carboxypeptidase
I5102_RS11250	COG0436	Aminotransferase
I5102_RS11260	COG0386	Belongs to the glutathione peroxidase family
I5102_RS11265	COG1846	Transcriptional regulator
I5102_RS11270	COG5002	protein histidine kinase activity
I5102_RS11270	COG2205	protein histidine kinase activity
I5102_RS11270	COG0784	Response regulator, receiver
I5102_RS11275	COG2255	four-way junction helicase activity
I5102_RS11280	COG1956	GAF domain-containing protein
I5102_RS11285	COG0625	glutathione transferase activity
I5102_RS11380	COG0625	glutathione transferase activity
I5102_RS11385	COG1131	(ABC) transporter
I5102_RS11390	COG0842	Transport permease protein
I5102_RS11435	COG2188	Transcriptional regulator
I5102_RS11445	COG2853	Lipoprotein
I5102_RS11455	COG0745	RESPONSE REGULATOR receiver
I5102_RS11490	COG3179	chitinase
I5102_RS11525	COG1335	isochorismatase
I5102_RS11580	COG3655	Transcriptional regulator
I5102_RS11620	COG2116	formate transmembrane transporter activity
I5102_RS11625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS11675	COG1051	belongs to the nudix hydrolase family
I5102_RS11685	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5102_RS11685	COG1024	Enoyl-CoA hydratase
I5102_RS11695	COG2837	iron assimilation
I5102_RS11780	COG1238	metal cluster binding
I5102_RS11790	COG1295	ribonuclease BN
I5102_RS11810	COG2356	endonuclease I
I5102_RS11820	COG0024	Methionine aminopeptidase
I5102_RS12045	COG0542	response to heat
I5102_RS12080	COG0789	Transcriptional regulator
I5102_RS12090	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS12090	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5102_RS12095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
I5102_RS12100	COG0243	molybdopterin cofactor binding
I5102_RS12120	COG1280	lysine exporter protein (LysE YggA)
I5102_RS12135	COG0542	response to heat
I5102_RS12205	COG1607	acyl-coa hydrolase
I5102_RS12210	COG1959	2 iron, 2 sulfur cluster binding
I5102_RS12220	COG2819	hydrolase of the alpha beta superfamily
I5102_RS12265	COG0583	DNA-binding transcription factor activity
I5102_RS12275	COG4106	trans-aconitate 2-methyltransferase activity
I5102_RS12295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I5102_RS12300	COG1459	type II secretion system
I5102_RS12310	COG2165	general secretion pathway protein
I5102_RS12350	COG0720	synthase
I5102_RS12355	COG3604	Transcriptional regulator
I5102_RS12415	COG0840	transmembrane signaling receptor activity
I5102_RS12420	COG2056	Na+-H+ antiporter family
I5102_RS12435	COG2226	methyltransferase
I5102_RS12530	COG2153	protein acetylation
I5102_RS12535	COG2850	peptidyl-arginine hydroxylation
I5102_RS12575	COG1278	Cold shock
I5102_RS12585	COG0542	response to heat
I5102_RS12590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
I5102_RS12605	COG0492	ferredoxin-NADP+ reductase activity
I5102_RS12620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I5102_RS12635	COG0435	Glutathione S-transferase
I5102_RS12640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I5102_RS12645	COG2920	part of a sulfur-relay system
I5102_RS12685	COG0583	DNA-binding transcription factor activity
I5102_RS12690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5102_RS12695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS12705	COG1960	acyl-CoA dehydrogenase activity
I5102_RS12710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS12720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS12735	COG2197	response regulator
I5102_RS12740	COG4771	TonB-dependent receptor
I5102_RS12780	COG0784	Response regulator, receiver
I5102_RS12780	COG2198	Histidine kinase
I5102_RS12780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS12780	COG2205	protein histidine kinase activity
I5102_RS12835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I5102_RS12840	COG1674	ftsk spoiiie
I5102_RS12880	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I5102_RS12920	COG0454	-acetyltransferase
I5102_RS12935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
I5102_RS12980	COG1724	mRNA binding
I5102_RS13130	COG3179	chitinase
I5102_RS13150	COG2135	peptidase activity
I5102_RS13165	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5102_RS13180	COG1522	sequence-specific DNA binding
I5102_RS13210	COG4191	Histidine kinase
I5102_RS13235	COG3706	GGDEF domain
I5102_RS13235	COG4251	negative regulation of phosphorylation
I5102_RS13235	COG5001	Diguanylate cyclase
I5102_RS13235	COG2203	Gaf domain
I5102_RS13260	COG0659	secondary active sulfate transmembrane transporter activity
I5102_RS13300	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS13310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I5102_RS13320	COG0183	Belongs to the thiolase family
I5102_RS13325	COG1960	acyl-CoA dehydrogenase activity
I5102_RS13375	COG0729	surface antigen
I5102_RS13385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I5102_RS13390	COG2267	carboxylic ester hydrolase activity
I5102_RS13395	COG2453	phosphatase
I5102_RS13395	COG0671	phosphoesterase, PA-phosphatase related
I5102_RS13410	COG4589	Belongs to the CDS family
I5102_RS13415	COG0667	Aldo Keto reductase
I5102_RS13425	COG1115	amino acid carrier protein
I5102_RS13435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I5102_RS13455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS13460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS13465	COG1538	Outer membrane efflux protein
I5102_RS13525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5102_RS13525	COG0543	2 iron, 2 sulfur cluster binding
I5102_RS13530	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
I5102_RS13535	COG4638	Rieske (2fe-2S)
I5102_RS13550	COG4948	Mandelate Racemase Muconate Lactonizing
I5102_RS13560	COG3485	protocatechuate 3,4-dioxygenase
I5102_RS13595	COG2807	transmembrane transport
I5102_RS13600	COG0590	tRNA wobble adenosine to inosine editing
I5102_RS13615	COG2318	DinB family
I5102_RS13675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5102_RS13680	COG2863	cytochrome
I5102_RS13685	COG3258	Cytochrome c
I5102_RS13690	COG0642	Histidine kinase
I5102_RS13725	COG0625	glutathione transferase activity
I5102_RS13745	COG0583	DNA-binding transcription factor activity
I5102_RS13750	COG1595	DNA-templated transcription, initiation
I5102_RS13755	COG3712	iron ion homeostasis
I5102_RS13795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5102_RS13805	COG2382	esterase
I5102_RS13825	COG0583	DNA-binding transcription factor activity
I5102_RS13845	COG1760	l-serine dehydratase
I5102_RS13850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
I5102_RS13885	COG2217	Heavy metal translocating P-type atpase
I5102_RS13900	COG0583	DNA-binding transcription factor activity
I5102_RS13915	COG1566	PFAM secretion protein HlyD family protein
I5102_RS14005	COG1335	isochorismatase
I5102_RS14015	COG0583	DNA-binding transcription factor activity
I5102_RS14055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I5102_RS14060	COG1121	(ABC) transporter
I5102_RS14150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS14175	COG0735	belongs to the Fur family
I5102_RS14185	COG1304	FMN binding
I5102_RS14215	COG4566	intracellular signal transduction
I5102_RS14305	COG3829	transcription factor binding
I5102_RS14330	COG3829	transcription factor binding
I5102_RS14335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I5102_RS14340	COG0584	glycerophosphoryl diester phosphodiesterase
I5102_RS14345	COG2011	ABC-type metal ion transport system permease component
I5102_RS14355	COG1464	Belongs to the NlpA lipoprotein family
I5102_RS14380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5102_RS14385	COG1070	Carbohydrate kinase
I5102_RS14390	COG0246	Mannitol dehydrogenase
I5102_RS14405	COG1175	transmembrane transport
I5102_RS14425	COG4771	TonB-dependent receptor
I5102_RS14440	COG1917	Cupin 2, conserved barrel domain protein
I5102_RS14440	COG4977	sequence-specific DNA binding
I5102_RS14455	COG1116	anion transmembrane transporter activity
I5102_RS14460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I5102_RS14465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS14500	COG3265	gluconokinase activity
I5102_RS14505	COG1609	Transcriptional regulator
I5102_RS14515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS14520	COG0583	DNA-binding transcription factor activity
I5102_RS14540	COG1396	sequence-specific DNA binding
I5102_RS14550	COG2175	clavaminate synthase activity
I5102_RS14560	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
I5102_RS14565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS14590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5102_RS14590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I5102_RS14600	COG3469	chitinase activity
I5102_RS14605	COG2188	Transcriptional regulator
I5102_RS14610	COG1053	succinate dehydrogenase
I5102_RS14625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I5102_RS14655	COG4772	TonB-dependent receptor
I5102_RS14700	COG0431	NADPH-dependent FMN reductase
I5102_RS14705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I5102_RS14715	COG0640	Transcriptional regulator
I5102_RS14720	COG2207	Transcriptional regulator
I5102_RS14725	COG1064	alcohol dehydrogenase
I5102_RS14750	COG1309	transcriptional regulator
I5102_RS14760	COG2329	Antibiotic biosynthesis monooxygenase
I5102_RS14795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5102_RS14805	COG1609	Transcriptional regulator
I5102_RS14835	COG0252	asparaginase activity
I5102_RS14840	COG1115	amino acid carrier protein
I5102_RS14885	COG1053	succinate dehydrogenase
I5102_RS14895	COG0728	peptidoglycan biosynthetic process
I5102_RS14955	COG2258	MOSC domain
I5102_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS14990	COG2508	Transcriptional regulator
I5102_RS15000	COG4447	cellulose binding
I5102_RS15005	COG2409	Drug exporters of the RND superfamily
I5102_RS15025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS15040	COG2072	flavoprotein involved in K transport
I5102_RS15060	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS15065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I5102_RS15075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5102_RS15080	COG3162	membrane
I5102_RS15085	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS15090	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS15120	COG3008	intermembrane lipid transfer
I5102_RS15125	COG2995	paraquat-inducible protein a
I5102_RS15130	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS15140	COG4948	Mandelate Racemase Muconate Lactonizing
I5102_RS15145	COG2271	Major facilitator Superfamily
I5102_RS15160	COG3618	amidohydrolase
I5102_RS15165	COG2271	Major facilitator Superfamily
I5102_RS15200	COG0765	amino acid transport
I5102_RS15205	COG0765	amino acid transport
I5102_RS15220	COG2084	Dehydrogenase
I5102_RS15230	COG2130	NADP-dependent
I5102_RS15235	COG1309	transcriptional regulator
I5102_RS15255	COG0366	Alpha amylase catalytic
I5102_RS15260	COG0517	IMP dehydrogenase activity
I5102_RS15290	COG2890	protein-(glutamine-N5) methyltransferase activity
I5102_RS15305	COG4191	Histidine kinase
I5102_RS15305	COG0784	Response regulator, receiver
I5102_RS15335	COG1363	Peptidase, m42
I5102_RS15375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
I5102_RS15415	COG3568	Endonuclease Exonuclease Phosphatase
I5102_RS15420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5102_RS15425	COG0392	lysyltransferase activity
I5102_RS15435	COG0366	Alpha amylase catalytic
I5102_RS15455	COG1285	pathogenesis
I5102_RS15475	COG0058	SHG alpha-glucan phosphorylase activity
I5102_RS15490	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS15495	COG1546	Belongs to the CinA family
I5102_RS15525	COG2323	membrane
I5102_RS15545	COG3121	Chaperone
I5102_RS15555	COG3188	usher protein
I5102_RS15560	COG3121	Chaperone
I5102_RS15570	COG3969	phosphoadenosine phosphosulfate
I5102_RS15580	COG1475	DNA binding
I5102_RS15585	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS15590	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
I5102_RS15595	COG0583	DNA-binding transcription factor activity
I5102_RS15615	COG1063	alcohol dehydrogenase
I5102_RS15625	COG2169	Transcriptional regulator
I5102_RS15625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5102_RS15640	COG0583	DNA-binding transcription factor activity
I5102_RS15645	COG2814	Major facilitator Superfamily
I5102_RS15665	COG1984	allophanate hydrolase subunit 2
I5102_RS15675	COG0028	Belongs to the TPP enzyme family
I5102_RS15685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
I5102_RS15690	COG1045	serine acetyltransferase
I5102_RS15695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I5102_RS15715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5102_RS15720	COG0300	oxidoreductase activity
I5102_RS15755	COG2814	Major facilitator Superfamily
I5102_RS15765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I5102_RS15785	COG0596	Alpha beta hydrolase
I5102_RS15790	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
I5102_RS15795	COG0367	asparagine synthase
I5102_RS15805	COG1522	sequence-specific DNA binding
I5102_RS15820	COG1113	amino acid transport
I5102_RS15825	COG2010	Cytochrome c
I5102_RS15830	COG2010	Cytochrome c
I5102_RS15855	COG5001	Diguanylate cyclase
I5102_RS15870	COG2192	nodulation
I5102_RS15875	COG2814	Major facilitator Superfamily
I5102_RS15905	COG1104	cysteine desulfurase activity
I5102_RS15910	COG4172	Belongs to the ABC transporter superfamily
I5102_RS15915	COG4239	(ABC) transporter, permease
I5102_RS15920	COG4174	ABC transporter (Permease)
I5102_RS15930	COG4771	TonB-dependent receptor
I5102_RS15945	COG0583	DNA-binding transcription factor activity
I5102_RS15965	COG1595	DNA-templated transcription, initiation
I5102_RS15980	COG2207	Transcriptional regulator
I5102_RS16000	COG0564	pseudouridine synthase activity
I5102_RS16010	COG0531	amino acid
I5102_RS16015	COG0174	glutamine synthetase
I5102_RS16040	COG0028	Belongs to the TPP enzyme family
I5102_RS16055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5102_RS16075	COG1522	sequence-specific DNA binding
I5102_RS16115	COG1309	transcriptional regulator
I5102_RS16120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS16125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS16135	COG3204	pilus organization
I5102_RS16140	COG0789	Transcriptional regulator
I5102_RS16145	COG1960	acyl-CoA dehydrogenase activity
I5102_RS16150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I5102_RS16180	COG0179	Fumarylacetoacetate (FAA) hydrolase
I5102_RS16190	COG2271	Major facilitator Superfamily
I5102_RS16195	COG3829	transcription factor binding
I5102_RS16195	COG3290	protein histidine kinase activity
I5102_RS16200	COG2610	gluconate transmembrane transporter activity
I5102_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS16210	COG2031	fatty acid transporter
I5102_RS16225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I5102_RS16230	COG0583	DNA-binding transcription factor activity
I5102_RS16235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I5102_RS16240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5102_RS16260	COG2205	protein histidine kinase activity
I5102_RS16325	COG3851	Histidine kinase
I5102_RS16345	COG0784	Response regulator, receiver
I5102_RS16345	COG2205	protein histidine kinase activity
I5102_RS16365	COG2194	sulfuric ester hydrolase activity
I5102_RS16420	COG5434	Belongs to the glycosyl hydrolase 28 family
I5102_RS16760	COG0488	(ABC) transporter
I5102_RS16775	COG0583	DNA-binding transcription factor activity
I5102_RS16780	COG1278	Cold shock
I5102_RS16830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I5102_RS16835	COG1609	Transcriptional regulator
I5102_RS16840	COG1172	Belongs to the binding-protein-dependent transport system permease family
I5102_RS16845	COG1129	ABC transporter
I5102_RS16870	COG2010	Cytochrome c
I5102_RS16875	COG0753	catalase activity
I5102_RS16900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
I5102_RS16905	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
I5102_RS16910	COG2080	2 iron, 2 sulfur cluster binding
I5102_RS16935	COG1944	ATP diphosphatase activity
I5102_RS16955	COG4771	TonB-dependent receptor
I5102_RS16960	COG0275	rRNA processing
I5102_RS16965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I5102_RS16965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I5102_RS16980	COG0579	oxidoreductase
I5102_RS17010	COG1595	DNA-templated transcription, initiation
I5102_RS17015	COG3712	iron ion homeostasis
I5102_RS17035	COG2814	Major facilitator Superfamily
I5102_RS17085	COG2197	response regulator
I5102_RS17110	COG2366	antibiotic biosynthetic process
I5102_RS17125	COG0625	glutathione transferase activity
I5102_RS17140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I5102_RS17145	COG0417	DNA replication proofreading
I5102_RS17190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS17260	COG1309	transcriptional regulator
I5102_RS17280	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
I5102_RS17285	COG0583	DNA-binding transcription factor activity
I5102_RS17295	COG2354	Protein conserved in bacteria
I5102_RS17300	COG3278	Belongs to the heme-copper respiratory oxidase family
I5102_RS17310	COG2239	Acts as a magnesium transporter
I5102_RS17325	COG5001	Diguanylate cyclase
I5102_RS17325	COG2203	Gaf domain
I5102_RS17325	COG3706	GGDEF domain
I5102_RS17325	COG4251	negative regulation of phosphorylation
I5102_RS17330	COG4977	sequence-specific DNA binding
I5102_RS17335	COG3813	Protein conserved in bacteria
I5102_RS17395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5102_RS17420	COG0604	alcohol dehydrogenase
I5102_RS17425	COG0616	signal peptide processing
I5102_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS17455	COG0583	DNA-binding transcription factor activity
I5102_RS17480	COG1024	Enoyl-CoA hydratase
I5102_RS17490	COG0531	amino acid
I5102_RS17505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I5102_RS17525	COG0741	lytic transglycosylase activity
I5102_RS17525	COG1388	LysM domain
I5102_RS17530	COG4166	transmembrane transport
I5102_RS17535	COG4166	transmembrane transport
I5102_RS17540	COG4174	ABC transporter (Permease)
I5102_RS17545	COG4239	(ABC) transporter, permease
I5102_RS17550	COG4172	Belongs to the ABC transporter superfamily
I5102_RS17560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I5102_RS17575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I5102_RS17595	COG0745	RESPONSE REGULATOR receiver
I5102_RS17600	COG2205	protein histidine kinase activity
I5102_RS17605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5102_RS17650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I5102_RS17670	COG0589	response to stress
I5102_RS17690	COG3707	response regulator
I5102_RS17700	COG2223	nitrite transmembrane transporter activity
I5102_RS17705	COG0515	serine threonine protein kinase
I5102_RS17710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I5102_RS17715	COG2146	nitrite reductase [NAD(P)H] activity
I5102_RS17720	COG0243	molybdopterin cofactor binding
I5102_RS17740	COG0668	transmembrane transport
I5102_RS17775	COG0189	ligase activity
I5102_RS17775	COG4067	protein conserved in archaea
I5102_RS17815	COG2909	trisaccharide binding
I5102_RS17820	COG2909	trisaccharide binding
I5102_RS17855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I5102_RS17905	COG0519	Catalyzes the synthesis of GMP from XMP
I5102_RS17920	COG0667	Aldo Keto reductase
I5102_RS17935	COG0183	Belongs to the thiolase family
I5102_RS17955	COG1305	Transglutaminase-like
I5102_RS17965	COG2308	Evidence 4 Homologs of previously reported genes of
I5102_RS17990	COG1317	bacterial-type flagellum organization
I5102_RS18100	COG4789	Type iii secretion
I5102_RS18150	COG4790	Type iii secretion
I5102_RS18155	COG4794	Type iii secretion
I5102_RS18160	COG4791	protein targeting
I5102_RS18165	COG4792	protein secretion
I5102_RS18245	COG2840	Smr protein MutS2
I5102_RS18265	COG0515	serine threonine protein kinase
I5102_RS18265	COG2815	serine threonine protein kinase
I5102_RS18305	COG2204	response regulator
I5102_RS18350	COG0625	glutathione transferase activity
I5102_RS18355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I5102_RS18370	COG3135	benzoate transporter
I5102_RS18385	COG2130	NADP-dependent
I5102_RS18405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I5102_RS18445	COG0745	RESPONSE REGULATOR receiver
I5102_RS18450	COG2205	protein histidine kinase activity
I5102_RS18475	COG1960	acyl-CoA dehydrogenase activity
I5102_RS18485	COG1024	Enoyl-CoA hydratase
I5102_RS18490	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5102_RS18495	COG2186	Transcriptional regulator
I5102_RS18500	COG2807	transmembrane transport
I5102_RS18505	COG0628	permease
I5102_RS18515	COG0625	glutathione transferase activity
I5102_RS18545	COG1022	Amp-dependent synthetase and ligase
I5102_RS18575	COG0784	Response regulator, receiver
I5102_RS18575	COG2205	protein histidine kinase activity
I5102_RS18575	COG5002	protein histidine kinase activity
I5102_RS18615	COG1846	Transcriptional regulator
I5102_RS18620	COG2080	2 iron, 2 sulfur cluster binding
I5102_RS18625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
I5102_RS18625	COG2010	Cytochrome c
I5102_RS18630	COG2010	Cytochrome c
I5102_RS18630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
I5102_RS18635	COG2207	Transcriptional regulator
I5102_RS18710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I5102_RS18715	COG1053	succinate dehydrogenase
I5102_RS18720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
I5102_RS18725	COG2009	succinate dehydrogenase
I5102_RS18755	COG2084	Dehydrogenase
I5102_RS18770	COG3738	Protein conserved in bacteria
I5102_RS18795	COG0251	oxidation-reduction process
I5102_RS18800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS18810	COG0174	glutamine synthetase
I5102_RS18815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS18835	COG0840	transmembrane signaling receptor activity
I5102_RS18850	COG3278	Belongs to the heme-copper respiratory oxidase family
I5102_RS18865	COG2010	Cytochrome c
I5102_RS18870	COG3278	Belongs to the heme-copper respiratory oxidase family
I5102_RS18885	COG2010	Cytochrome c
I5102_RS18890	COG0348	domain, Protein
I5102_RS18900	COG2217	Heavy metal translocating P-type atpase
I5102_RS18940	COG2076	Multidrug Resistance protein
I5102_RS18970	COG1960	acyl-CoA dehydrogenase activity
I5102_RS18985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I5102_RS19015	COG1196	nuclear chromosome segregation
I5102_RS19045	COG0402	S-adenosylhomocysteine deaminase activity
I5102_RS19050	COG1247	-acetyltransferase
I5102_RS19070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I5102_RS19080	COG0384	phenazine biosynthesis protein PhzF
I5102_RS19110	COG5006	permease, DMT superfamily
I5102_RS19125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I5102_RS19140	COG3795	YCII-related domain
I5102_RS19150	COG2814	Major facilitator Superfamily
I5102_RS19155	COG4941	Belongs to the sigma-70 factor family
I5102_RS19165	COG3795	YCII-related domain
I5102_RS19175	COG2197	response regulator
I5102_RS19180	COG1982	Orn Lys Arg decarboxylase major
I5102_RS19185	COG0189	ligase activity
I5102_RS19190	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS19205	COG0765	amino acid transport
I5102_RS19210	COG0765	amino acid transport
I5102_RS19215	COG1126	abc transporter atp-binding protein
I5102_RS19240	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS19255	COG1253	flavin adenine dinucleotide binding
I5102_RS19260	COG0300	oxidoreductase activity
I5102_RS19270	COG0583	DNA-binding transcription factor activity
I5102_RS19275	COG3591	Belongs to the peptidase S1B family
I5102_RS19275	COG1864	DNA RNA non-specific endonuclease
I5102_RS19280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I5102_RS19285	COG4319	ketosteroid isomerase
I5102_RS19300	COG4774	siderophore transport
I5102_RS19345	COG2814	Major facilitator Superfamily
I5102_RS19365	COG0583	DNA-binding transcription factor activity
I5102_RS19375	COG0121	glutamine amidotransferase
I5102_RS19405	COG3712	iron ion homeostasis
I5102_RS19410	COG1595	DNA-templated transcription, initiation
I5102_RS19425	COG1230	cation diffusion facilitator family transporter
I5102_RS19430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I5102_RS19455	COG2252	PERMEase
I5102_RS19515	COG2233	PERMEase
I5102_RS19530	COG1309	transcriptional regulator
I5102_RS19545	COG3622	Belongs to the hyi family
I5102_RS19550	COG2084	Dehydrogenase
I5102_RS19560	COG0469	pyruvate kinase activity
I5102_RS19565	COG4413	Urea transporter
I5102_RS19570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I5102_RS19585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
I5102_RS19595	COG3192	ethanolamine utilization protein
I5102_RS19610	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5102_RS19615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I5102_RS19690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I5102_RS19705	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS19710	COG1496	oxidoreductase activity
I5102_RS19735	COG0835	chemotaxis
I5102_RS19745	COG1192	Involved in chromosome partitioning
I5102_RS19750	COG1360	Flagellar Motor Protein
I5102_RS19755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I5102_RS19765	COG2198	Histidine kinase
I5102_RS19765	COG0643	Histidine kinase
I5102_RS19765	COG0784	Response regulator, receiver
I5102_RS19795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I5102_RS19800	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
I5102_RS19820	COG1987	bacterial-type flagellum assembly
I5102_RS19860	COG2832	Protein of unknown function (DUF454)
I5102_RS19875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS19880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS19890	COG3300	MHYT domain
I5102_RS19890	COG5001	Diguanylate cyclase
I5102_RS19920	COG0488	(ABC) transporter
I5102_RS19975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5102_RS19980	COG0583	DNA-binding transcription factor activity
I5102_RS19995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I5102_RS20005	COG1196	nuclear chromosome segregation
I5102_RS20005	COG3264	Mechanosensitive ion channel
I5102_RS20010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
I5102_RS20010	COG0116	Belongs to the methyltransferase superfamily
I5102_RS20020	COG0210	DNA helicase
I5102_RS20045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I5102_RS20150	COG1960	acyl-CoA dehydrogenase activity
I5102_RS20170	COG0406	alpha-ribazole phosphatase activity
I5102_RS20200	COG0778	Nitroreductase
I5102_RS20215	COG4206	TonB-dependent receptor
I5102_RS20225	COG1802	Transcriptional regulator
I5102_RS20235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS20270	COG0477	Major facilitator Superfamily
I5102_RS20290	COG0765	amino acid transport
I5102_RS20300	COG1126	abc transporter atp-binding protein
I5102_RS20310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I5102_RS20315	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS20365	COG0784	Response regulator, receiver
I5102_RS20365	COG4191	Histidine kinase
I5102_RS20405	COG1289	transmembrane transporter activity
I5102_RS20420	COG2207	Transcriptional regulator
I5102_RS20440	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5102_RS20445	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5102_RS20455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
I5102_RS20480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I5102_RS20490	COG0318	PFAM AMP-dependent synthetase and ligase
I5102_RS20495	COG0367	asparagine synthase
I5102_RS20505	COG2211	Major facilitator Superfamily
I5102_RS20555	COG1335	isochorismatase
I5102_RS20560	COG0583	DNA-binding transcription factor activity
I5102_RS20570	COG0791	NLP P60 protein
I5102_RS20575	COG0791	NLP P60 protein
I5102_RS20585	COG3829	transcription factor binding
I5102_RS20600	COG2818	Glycosylase
I5102_RS20625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
I5102_RS20630	COG1960	acyl-CoA dehydrogenase activity
I5102_RS20640	COG0625	glutathione transferase activity
I5102_RS20660	COG5001	Diguanylate cyclase
I5102_RS20660	COG5002	protein histidine kinase activity
I5102_RS20660	COG3447	MASE1 domain protein
I5102_RS20680	COG4459	periplasmic nitrate reductase
I5102_RS20685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5102_RS20685	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
I5102_RS20690	COG3062	negative regulation of establishment of protein localization
I5102_RS20700	COG3043	anaerobic respiration
I5102_RS20705	COG3005	denitrification pathway
I5102_RS20710	COG2951	lytic endotransglycosylase activity
I5102_RS20715	COG0861	Integral membrane protein TerC family
I5102_RS20720	COG0753	catalase activity
I5102_RS20740	COG2977	Belongs to the P-Pant transferase superfamily
I5102_RS20745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I5102_RS20760	COG2226	methyltransferase
I5102_RS20775	COG2205	protein histidine kinase activity
I5102_RS20780	COG0745	RESPONSE REGULATOR receiver
I5102_RS20785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I5102_RS20785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I5102_RS20790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I5102_RS20795	COG1943	Transposase
I5102_RS20830	COG0531	amino acid
I5102_RS20860	COG0583	DNA-binding transcription factor activity
I5102_RS20865	COG3257	ureidoglycine aminohydrolase activity
I5102_RS20880	COG3321	synthase
I5102_RS20880	COG0604	alcohol dehydrogenase
I5102_RS20880	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS20885	COG2197	response regulator
I5102_RS20925	COG0583	DNA-binding transcription factor activity
I5102_RS20930	COG0667	Aldo Keto reductase
I5102_RS20955	COG0242	peptide deformylase activity
I5102_RS20965	COG2199	diguanylate cyclase activity
I5102_RS20970	COG2885	chlorophyll binding
I5102_RS21000	COG1132	(ABC) transporter
I5102_RS21010	COG4628	conserved protein (DUF2132)
I5102_RS21015	COG2133	pyrroloquinoline quinone binding
I5102_RS21030	COG2207	Transcriptional regulator
I5102_RS21035	COG0477	Major facilitator Superfamily
I5102_RS21050	COG2882	bacterial-type flagellum organization
I5102_RS21105	COG1516	flagellar protein fliS
I5102_RS21110	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
I5102_RS21120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I5102_RS21125	COG1216	Glycosyl transferase, family 2
I5102_RS21125	COG0438	transferase activity, transferring glycosyl groups
I5102_RS21130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I5102_RS21135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5102_RS21145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
I5102_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS21180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I5102_RS21200	COG1256	bacterial-type flagellum assembly
I5102_RS21225	COG4787	bacterial-type flagellum-dependent cell motility
I5102_RS21235	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
I5102_RS21245	COG1815	bacterial-type flagellum-dependent cell motility
I5102_RS21290	COG0326	Molecular chaperone. Has ATPase activity
I5102_RS21305	COG3189	MarR family transcriptional regulator
I5102_RS21325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I5102_RS21340	COG2212	antiporter activity
I5102_RS21345	COG1863	multisubunit Na H antiporter MnhE subunit
I5102_RS21350	COG0651	ATP synthesis coupled electron transport
I5102_RS21355	COG1006	Multisubunit Na H antiporter MnhC subunit
I5102_RS21360	COG2111	Na H antiporter
I5102_RS21360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I5102_RS21365	COG3133	Outer membrane lipoprotein
I5102_RS21375	COG1929	Belongs to the glycerate kinase type-1 family
I5102_RS21380	COG2610	gluconate transmembrane transporter activity
I5102_RS21385	COG3835	regulator
I5102_RS21395	COG2885	chlorophyll binding
I5102_RS21410	COG1199	ATP-dependent helicase activity
I5102_RS21450	COG2860	membrane
I5102_RS21465	COG0653	protein targeting
I5102_RS21470	COG0625	glutathione transferase activity
I5102_RS21495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS21500	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS21525	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS21530	COG1960	acyl-CoA dehydrogenase activity
I5102_RS21535	COG1024	Enoyl-CoA hydratase
I5102_RS21540	COG1960	acyl-CoA dehydrogenase activity
I5102_RS21550	COG2814	Major facilitator Superfamily
I5102_RS21555	COG2030	dehydratase
I5102_RS21640	COG4974	Belongs to the 'phage' integrase family
I5102_RS21665	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
I5102_RS21670	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
I5102_RS21685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I5102_RS21695	COG0425	Belongs to the sulfur carrier protein TusA family
I5102_RS21750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I5102_RS21755	COG3188	usher protein
I5102_RS21790	COG1192	Involved in chromosome partitioning
I5102_RS21940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I5102_RS21945	COG1278	Cold shock
I5102_RS21955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I5102_RS21965	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I5102_RS21970	COG3657	addiction module killer protein
I5102_RS21995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I5102_RS22090	COG3344	reverse transcriptase
I5102_RS22155	COG1074	ATP-dependent DNA helicase activity
I5102_RS22265	COG3609	addiction module antidote protein, CC2985 family
I5102_RS22275	COG3459	Glycosyltransferase 36 associated
I5102_RS22305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I5102_RS22330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
I5102_RS22345	COG0602	queuosine metabolic process
I5102_RS22350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
I5102_RS22380	COG0824	Thioesterase
I5102_RS22410	COG0783	Belongs to the Dps family
I5102_RS22455	COG3118	belongs to the thioredoxin family
I5102_RS22490	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
I5102_RS22505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I5102_RS22545	COG3122	Protein conserved in bacteria
I5102_RS22555	COG3956	TIGRFAM MazG family protein
I5102_RS22560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I5102_RS22590	COG0784	Response regulator, receiver
I5102_RS22590	COG2205	protein histidine kinase activity
I5102_RS22590	COG5002	protein histidine kinase activity
I5102_RS22595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I5102_RS22645	COG3038	cytochrome b561
I5102_RS22660	COG4807	Protein conserved in bacteria
I5102_RS22670	COG2239	Acts as a magnesium transporter
I5102_RS22740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
I5102_RS22835	COG2301	Belongs to the HpcH HpaI aldolase family
I5102_RS22845	COG2079	MmgE PrpD family protein
I5102_RS22855	COG1960	acyl-CoA dehydrogenase activity
I5102_RS22860	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
I5102_RS22865	COG0583	DNA-binding transcription factor activity
I5102_RS22870	COG0583	DNA-binding transcription factor activity
I5102_RS22920	COG1113	amino acid transport
I5102_RS22940	COG3321	synthase
I5102_RS22940	COG0604	alcohol dehydrogenase
I5102_RS22940	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS22950	COG5002	protein histidine kinase activity
I5102_RS22950	COG5001	Diguanylate cyclase
I5102_RS22970	COG0271	Belongs to the BolA IbaG family
I5102_RS23010	COG0492	ferredoxin-NADP+ reductase activity
I5102_RS23015	COG0450	alkyl hydroperoxide reductase
I5102_RS23050	COG1307	EDD domain protein, DegV family
I5102_RS23060	COG1309	transcriptional regulator
I5102_RS23065	COG0386	Belongs to the glutathione peroxidase family
I5102_RS23090	COG0204	Acyl-transferase
I5102_RS23095	COG2885	chlorophyll binding
I5102_RS23100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I5102_RS23115	COG2267	carboxylic ester hydrolase activity
I5102_RS23165	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
I5102_RS23200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I5102_RS23215	COG0546	phosphoglycolate phosphatase activity
I5102_RS23230	COG3023	N-Acetylmuramoyl-L-alanine amidase
I5102_RS23245	COG0656	L-ascorbic acid biosynthetic process
I5102_RS23270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I5102_RS23280	COG1802	Transcriptional regulator
I5102_RS23290	COG0372	Belongs to the citrate synthase family
I5102_RS23305	COG2079	MmgE PrpD family protein
I5102_RS23320	COG1113	amino acid transport
I5102_RS23350	COG0583	DNA-binding transcription factor activity
I5102_RS23355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I5102_RS23365	COG4206	TonB-dependent receptor
I5102_RS23375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I5102_RS23440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5102_RS23520	COG3180	Ammonia monooxygenase
I5102_RS23530	COG2720	vancomycin resistance protein
I5102_RS23545	COG1960	acyl-CoA dehydrogenase activity
I5102_RS23550	COG1024	Enoyl-CoA hydratase
I5102_RS23570	COG2910	NAD(P)H-binding
I5102_RS23575	COG2015	COG2015, Alkyl sulfatase and related hydrolases
I5102_RS23650	COG4974	Belongs to the 'phage' integrase family
I5102_RS23660	COG4128	Pfam Zonular occludens toxin
I5102_RS23765	COG0583	DNA-binding transcription factor activity
I5102_RS23780	COG0463	Glycosyl transferase, family 2
I5102_RS23790	COG0154	amidase activity
I5102_RS23810	COG0583	DNA-binding transcription factor activity
I5102_RS23855	COG2831	hemolysin activation secretion protein
I5102_RS24000	COG0420	3'-5' exonuclease activity
I5102_RS24010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I5102_RS24015	COG1074	ATP-dependent DNA helicase activity
I5102_RS24020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
I5102_RS24025	COG0095	Lipoate-protein ligase
I5102_RS24030	COG0697	spore germination
I5102_RS24045	COG0840	transmembrane signaling receptor activity
I5102_RS24055	COG0306	phosphate transporter
I5102_RS24115	COG4964	Belongs to the GSP D family
I5102_RS24135	COG0433	COG0433 Predicted ATPase
I5102_RS24170	COG0788	formyltetrahydrofolate deformylase activity
I5102_RS24180	COG2925	Exonuclease
I5102_RS24210	COG0714	Associated with various cellular activities
I5102_RS24240	COG0589	response to stress
I5102_RS24250	COG1024	Enoyl-CoA hydratase
I5102_RS24260	COG3706	GGDEF domain
I5102_RS24280	COG0693	protein deglycase activity
I5102_RS24295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5102_RS24310	COG0154	amidase activity
I5102_RS24320	COG1473	amidohydrolase
I5102_RS24335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I5102_RS24340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I5102_RS24340	COG0426	domain, Protein
I5102_RS24360	COG0589	response to stress
I5102_RS24375	COG2814	Major facilitator Superfamily
I5102_RS24380	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS24395	COG1918	ferrous iron import across plasma membrane
I5102_RS24410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I5102_RS24450	COG1704	LemA family
I5102_RS24475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS24480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS24495	COG3642	lipopolysaccharide core region biosynthetic process
I5102_RS24505	COG2205	protein histidine kinase activity
I5102_RS24510	COG0745	RESPONSE REGULATOR receiver
I5102_RS24545	COG3030	protein affecting phage T7 exclusion by the F plasmid
I5102_RS24555	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS24580	COG0668	transmembrane transport
I5102_RS24590	COG0745	RESPONSE REGULATOR receiver
I5102_RS24605	COG2096	Adenosyltransferase
I5102_RS24610	COG0494	nUDIX hydrolase
I5102_RS24630	COG1196	nuclear chromosome segregation
I5102_RS24630	COG0741	lytic transglycosylase activity
I5102_RS24630	COG0739	heme binding
I5102_RS24675	COG0772	Belongs to the SEDS family
I5102_RS24690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I5102_RS24730	COG3107	peptidoglycan biosynthetic process
I5102_RS24745	COG2823	Periplasmic or secreted lipoprotein
I5102_RS24750	COG2969	positive regulation of protein catabolic process
I5102_RS24755	COG0625	glutathione transferase activity
I5102_RS24760	COG2857	Cytochrome c1
I5102_RS24765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I5102_RS24770	COG0723	plastoquinol--plastocyanin reductase activity
I5102_RS24785	COG0667	Aldo Keto reductase
I5102_RS24790	COG1960	acyl-CoA dehydrogenase activity
I5102_RS24805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I5102_RS24815	COG2945	thiolester hydrolase activity
I5102_RS24835	COG2951	lytic endotransglycosylase activity
I5102_RS24845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I5102_RS24885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I5102_RS24890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I5102_RS24895	COG1127	ABC transporter
I5102_RS24905	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
I5102_RS24920	COG1137	ATPase activity
I5102_RS24975	COG0312	modulator of DNA gyrase
I5102_RS24985	COG0312	modulator of DNA gyrase
I5102_RS24990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I5102_RS25000	COG1530	ribonuclease E activity
I5102_RS25015	COG1792	Involved in formation and maintenance of cell shape
I5102_RS25020	COG1077	Cell shape determining protein MreB Mrl
I5102_RS25040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I5102_RS25045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I5102_RS25050	COG4676	Protein conserved in bacteria
I5102_RS25055	COG5445	Predicted secreted protein (DUF2300)
I5102_RS25070	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
I5102_RS25075	COG4676	Protein conserved in bacteria
I5102_RS25080	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
I5102_RS25095	COG0747	negative chemotaxis
I5102_RS25100	COG0747	negative chemotaxis
I5102_RS25115	COG0747	negative chemotaxis
I5102_RS25125	COG0747	negative chemotaxis
I5102_RS25130	COG0601	transmembrane transport
I5102_RS25135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I5102_RS25140	COG0444	Belongs to the ABC transporter superfamily
I5102_RS25145	COG4608	Belongs to the ABC transporter superfamily
I5102_RS25160	COG1984	allophanate hydrolase subunit 2
I5102_RS25180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I5102_RS25185	COG4774	siderophore transport
I5102_RS25200	COG2194	sulfuric ester hydrolase activity
I5102_RS25210	COG0019	diaminopimelate decarboxylase activity
I5102_RS25225	COG3023	N-Acetylmuramoyl-L-alanine amidase
I5102_RS25315	COG1252	NADH dehydrogenase
I5102_RS25320	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I5102_RS25395	COG4969	Belongs to the N-Me-Phe pilin family
I5102_RS25435	COG1047	Peptidyl-prolyl cis-trans
I5102_RS25450	COG0196	riboflavin kinase activity
I5102_RS25465	COG3045	CreA protein
I5102_RS25490	COG0142	geranyltranstransferase activity
I5102_RS25505	COG0545	Peptidyl-prolyl cis-trans isomerase
I5102_RS25525	COG1067	ATP-dependent peptidase activity
I5102_RS25550	COG4650	regulator
I5102_RS25565	COG1690	Belongs to the RtcB family
I5102_RS25570	COG3541	Predicted nucleotidyltransferase
I5102_RS25590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I5102_RS25615	COG0577	efflux transmembrane transporter activity
I5102_RS25615	COG1136	(ABC) transporter
I5102_RS25620	COG0577	efflux transmembrane transporter activity
I5102_RS25620	COG1136	(ABC) transporter
I5102_RS25625	COG0488	(ABC) transporter
I5102_RS25645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I5102_RS25650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS25675	COG0523	cobalamin synthesis protein
I5102_RS25680	COG2879	small protein
I5102_RS25685	COG1966	Carbon starvation protein
I5102_RS25755	COG3608	succinylglutamate desuccinylase aspartoacylase
I5102_RS25755	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
I5102_RS25760	COG2010	Cytochrome c
I5102_RS25795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I5102_RS25805	COG0833	amino acid
I5102_RS25810	COG2119	membrane
I5102_RS25825	COG0501	Belongs to the peptidase M48B family
I5102_RS25830	COG0840	transmembrane signaling receptor activity
I5102_RS25835	COG2135	peptidase activity
I5102_RS25840	COG1285	pathogenesis
I5102_RS25900	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I5102_RS25955	COG1090	epimerase
I5102_RS25960	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
I5102_RS25970	COG0789	Transcriptional regulator
I5102_RS25990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I5102_RS26045	COG0012	GTP binding
I5102_RS26060	COG4974	Belongs to the 'phage' integrase family
I5102_RS26070	COG4128	Pfam Zonular occludens toxin
I5102_RS26130	COG3549	Plasmid maintenance system killer
I5102_RS26140	COG0288	reversible hydration of carbon dioxide
I5102_RS26150	COG0456	acetyltransferase
I5102_RS26195	COG1840	ABC-type Fe3 transport system, periplasmic component
I5102_RS26200	COG1178	ABC-type Fe3 transport system permease component
I5102_RS26205	COG3008	intermembrane lipid transfer
I5102_RS26210	COG2995	paraquat-inducible protein a
I5102_RS26215	COG2995	paraquat-inducible protein a
I5102_RS26255	COG1183	phosphatidylcholine synthase activity
I5102_RS26270	COG0028	Belongs to the TPP enzyme family
I5102_RS26285	COG3098	single-species biofilm formation
I5102_RS26295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I5102_RS26330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I5102_RS26335	COG4558	Periplasmic binding protein
I5102_RS26340	COG3720	iron ion transport
I5102_RS26345	COG4771	TonB-dependent receptor
I5102_RS26370	COG0436	Aminotransferase
I5102_RS26380	COG2321	neutral zinc metallopeptidase
I5102_RS26390	COG2252	PERMEase
I5102_RS26405	COG0436	Aminotransferase
I5102_RS26410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5102_RS26425	COG4191	Histidine kinase
I5102_RS26525	COG0195	Participates in both transcription termination and antitermination
I5102_RS26560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I5102_RS26625	COG0497	DNA recombination
I5102_RS26655	COG2186	Transcriptional regulator
I5102_RS26660	COG1620	l-lactate permease
I5102_RS26710	COG0697	spore germination
I5102_RS26730	COG0697	spore germination
I5102_RS26735	COG1522	sequence-specific DNA binding
I5102_RS26745	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS26765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5102_RS26775	COG0584	glycerophosphoryl diester phosphodiesterase
I5102_RS26795	COG0509	glycine decarboxylation via glycine cleavage system
I5102_RS26835	COG0531	amino acid
I5102_RS26850	COG3276	selenocysteine insertion sequence binding
I5102_RS26865	COG2864	formate dehydrogenase
I5102_RS26870	COG0437	4 iron, 4 sulfur cluster binding
I5102_RS26880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
I5102_RS26885	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS26885	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5102_RS26910	COG0463	Glycosyl transferase, family 2
I5102_RS26920	COG0534	Mate efflux family protein
I5102_RS26930	COG1283	sodium-dependent phosphate transmembrane transporter activity
I5102_RS26955	COG2162	N-hydroxyarylamine O-acetyltransferase activity
I5102_RS26980	COG4221	oxidoreductase activity
I5102_RS26985	COG1272	protein, Hemolysin III
I5102_RS27020	COG0023	Translation Initiation Factor
I5102_RS27105	COG2095	MarC family integral membrane protein
I5102_RS27110	COG0683	leucine binding
I5102_RS27125	COG0411	ABC transporter
I5102_RS27170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I5102_RS27185	COG0443	Heat shock 70 kDa protein
I5102_RS27210	COG0789	Transcriptional regulator
I5102_RS27215	COG2982	Protein involved in outer membrane biogenesis
I5102_RS27220	COG2193	ferroxidase activity
I5102_RS27230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I5102_RS27235	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
I5102_RS27295	COG3712	iron ion homeostasis
I5102_RS27300	COG1595	DNA-templated transcription, initiation
I5102_RS27320	COG2814	Major facilitator Superfamily
I5102_RS27330	COG0583	DNA-binding transcription factor activity
I5102_RS27355	COG4221	oxidoreductase activity
I5102_RS27360	COG2423	ornithine cyclodeaminase activity
I5102_RS27390	COG0583	DNA-binding transcription factor activity
I5102_RS27405	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
I5102_RS27445	COG0668	transmembrane transport
I5102_RS27465	COG5001	Diguanylate cyclase
I5102_RS27465	COG3300	MHYT domain
I5102_RS27475	COG0305	Participates in initiation and elongation during chromosome replication
I5102_RS27505	COG0557	exoribonuclease II activity
I5102_RS27535	COG0330	HflC and HflK could
I5102_RS27540	COG0330	HflC and HflK could
I5102_RS27545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I5102_RS27565	COG0860	N-Acetylmuramoyl-L-alanine amidase
I5102_RS27570	COG0802	atpase or kinase
I5102_RS27575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I5102_RS27575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
I5102_RS27625	COG5001	Diguanylate cyclase
I5102_RS27625	COG3300	MHYT domain
I5102_RS27630	COG0560	Phosphoserine phosphatase
I5102_RS27630	COG3830	Belongs to the UPF0237 family
I5102_RS27640	COG1988	membrane-bound metal-dependent
I5102_RS27655	COG3577	Aspartyl protease
I5102_RS27670	COG3150	esterase
I5102_RS27675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I5102_RS27685	COG0494	nUDIX hydrolase
I5102_RS27700	COG1538	Outer membrane efflux protein
I5102_RS27705	COG2249	NAD(P)H dehydrogenase (quinone) activity
I5102_RS27720	COG0045	succinate-CoA ligase (ADP-forming) activity
I5102_RS27725	COG1960	acyl-CoA dehydrogenase activity
I5102_RS27730	COG1024	Enoyl-CoA hydratase
I5102_RS27735	COG0833	amino acid
I5102_RS27765	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5102_RS27765	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS27775	COG1519	Transferase
I5102_RS27780	COG0583	DNA-binding transcription factor activity
I5102_RS27795	COG0667	Aldo Keto reductase
I5102_RS27805	COG1960	acyl-CoA dehydrogenase activity
I5102_RS27810	COG1960	acyl-CoA dehydrogenase activity
I5102_RS27815	COG0367	asparagine synthase
I5102_RS27840	COG1215	transferase activity, transferring glycosyl groups
I5102_RS27860	COG0438	transferase activity, transferring glycosyl groups
I5102_RS27865	COG2192	nodulation
I5102_RS27890	COG0438	transferase activity, transferring glycosyl groups
I5102_RS27895	COG0859	PFAM glycosyl transferase family 9
I5102_RS27900	COG0859	PFAM glycosyl transferase family 9
I5102_RS27935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
I5102_RS27940	COG1960	acyl-CoA dehydrogenase activity
I5102_RS27950	COG3264	Mechanosensitive ion channel
I5102_RS27950	COG1196	nuclear chromosome segregation
I5102_RS27960	COG0730	response to heat
I5102_RS27965	COG2873	o-acetylhomoserine
I5102_RS27980	COG1192	Involved in chromosome partitioning
I5102_RS27985	COG0583	DNA-binding transcription factor activity
I5102_RS27990	COG2814	Major facilitator Superfamily
I5102_RS28015	COG0493	'glutamate synthase
I5102_RS28020	COG0067	glutamate synthase
I5102_RS28020	COG0069	glutamate synthase activity
I5102_RS28020	COG0070	glutamate synthase
I5102_RS28070	COG0281	malic enzyme
I5102_RS28090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I5102_RS28200	COG0840	transmembrane signaling receptor activity
I5102_RS28210	COG1126	abc transporter atp-binding protein
I5102_RS28215	COG0765	amino acid transport
I5102_RS28245	COG1051	belongs to the nudix hydrolase family
I5102_RS28250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I5102_RS28255	COG0251	oxidation-reduction process
I5102_RS28285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5102_RS28305	COG2986	histidine ammonia-lyase
I5102_RS28310	COG4175	Glycine betaine
I5102_RS28315	COG4176	ABC-type proline glycine betaine transport system permease component
I5102_RS28335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I5102_RS28370	COG0402	S-adenosylhomocysteine deaminase activity
I5102_RS28420	COG0789	Transcriptional regulator
I5102_RS28425	COG1217	gtp-binding protein TYPA
I5102_RS28445	COG0668	transmembrane transport
I5102_RS28460	COG3852	Histidine kinase
I5102_RS28475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I5102_RS28505	COG4942	peptidase
I5102_RS28510	COG0793	Belongs to the peptidase S41A family
I5102_RS28515	COG2861	carbohydrate metabolic process
I5102_RS28575	COG0579	oxidoreductase
I5102_RS28585	COG1194	a g-specific adenine glycosylase
I5102_RS28595	COG0673	inositol 2-dehydrogenase activity
I5102_RS28605	COG1028	Short-chain dehydrogenase reductase Sdr
I5102_RS28650	COG1566	PFAM secretion protein HlyD family protein
I5102_RS28655	COG2814	Major facilitator Superfamily
I5102_RS28665	COG1088	dTDP-glucose 4,6-dehydratase activity
I5102_RS28670	COG1091	dTDP-4-dehydrorhamnose reductase activity
I5102_RS28735	COG1218	3'(2'),5'-bisphosphate nucleotidase
I5102_RS28740	COG0494	nUDIX hydrolase
I5102_RS28745	COG1011	Hydrolase
I5102_RS28750	COG1652	LysM domain
I5102_RS28760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
I5102_RS28780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I5102_RS28790	COG0824	Thioesterase
I5102_RS28795	COG1454	alcohol dehydrogenase
I5102_RS28800	COG1960	acyl-CoA dehydrogenase activity
I5102_RS28805	COG1250	3-hydroxyacyl-CoA dehydrogenase
I5102_RS28805	COG1024	Enoyl-CoA hydratase
I5102_RS28815	COG0778	Nitroreductase
I5102_RS28840	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I5102_RS28845	COG4067	protein conserved in archaea
I5102_RS28845	COG0189	ligase activity
I5102_RS28870	COG2183	response to ionizing radiation
I5102_RS28900	COG0306	phosphate transporter
I5102_RS28905	COG1392	Phosphate transport regulator
I5102_RS28910	COG3025	triphosphatase activity
I5102_RS28915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I5102_RS28945	COG1178	ABC-type Fe3 transport system permease component
I5102_RS28955	COG0583	DNA-binding transcription factor activity
I5102_RS28970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5102_RS28980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I5102_RS28985	COG0006	proline dipeptidase activity
I5102_RS29010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I5102_RS29020	COG0842	Transport permease protein
I5102_RS29025	COG1129	ABC transporter
I5102_RS29025	COG0842	Transport permease protein
I5102_RS29030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I5102_RS29045	COG2271	Major facilitator Superfamily
I5102_RS29090	COG0586	Pfam SNARE associated Golgi protein
I5102_RS29095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
I5102_RS29100	COG2050	protein possibly involved in aromatic compounds catabolism
I5102_RS29110	COG0672	)-iron permease
I5102_RS29115	COG1280	lysine exporter protein (LysE YggA)
I5102_RS29120	COG0861	Integral membrane protein TerC family
I5102_RS29130	COG0488	(ABC) transporter
I5102_RS29185	COG3275	phosphorelay sensor kinase activity
I5102_RS29220	COG0598	Magnesium transport protein CorA
I5102_RS29250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I5102_RS29315	COG0432	Pfam Uncharacterised protein family UPF0047
I5102_RS29320	COG0004	ammonium transporteR
I5102_RS29325	COG0347	Belongs to the P(II) protein family
I5102_RS29335	COG0606	chelatase, subunit chli
I5102_RS29340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5102_RS29350	COG0583	DNA-binding transcription factor activity
I5102_RS29365	COG0210	DNA helicase
I5102_RS29370	COG0028	Belongs to the TPP enzyme family
I5102_RS29380	COG0427	acetyl-CoA hydrolase
I5102_RS29390	COG1396	sequence-specific DNA binding
I5102_RS29390	COG1917	Cupin 2, conserved barrel domain protein
I5102_RS29400	COG0251	oxidation-reduction process
I5102_RS29430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I5102_RS29435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I5102_RS29440	COG2814	Major facilitator Superfamily
I5102_RS29445	COG1012	belongs to the aldehyde dehydrogenase family
I5102_RS29450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I5102_RS29470	COG0747	negative chemotaxis
I5102_RS29485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I5102_RS29525	COG3245	cytochrome
I5102_RS29545	COG0708	Exodeoxyribonuclease III
I5102_RS29560	COG1561	YicC-like family, N-terminal region
I5102_RS29575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I5102_RS29595	COG2169	Transcriptional regulator
I5102_RS29605	COG0583	DNA-binding transcription factor activity
I5102_RS29610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I5102_RS29645	COG3193	protein, possibly involved in utilization of glycolate and propanediol
I5102_RS29650	COG0247	lactate metabolic process
I5102_RS29655	COG0277	FAD linked oxidase domain protein
I5102_RS29660	COG0277	FAD linked oxidase domain protein
I5102_RS29665	COG2186	Transcriptional regulator
I5102_RS29695	COG1253	flavin adenine dinucleotide binding
I5102_RS29700	COG0739	heme binding
I5102_RS29720	COG0573	inorganic phosphate transmembrane transporter activity
I5102_RS29760	COG0477	Major facilitator Superfamily
I5102_RS29765	COG1607	acyl-coa hydrolase
I5102_RS29785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I5102_RS29790	COG4175	Glycine betaine
I5102_RS29795	COG4176	ABC-type proline glycine betaine transport system permease component
I5102_RS29805	COG1760	l-serine dehydratase
I5102_RS29820	COG0583	DNA-binding transcription factor activity
I5102_RS29830	COG0657	acetylesterase activity
I5102_RS29845	COG3246	L-lysine catabolic process to acetate
I5102_RS29900	COG1902	pentaerythritol trinitrate reductase activity
I5102_RS29900	COG0446	pyridine nucleotide-disulphide oxidoreductase
I5102_RS29905	COG0247	lactate metabolic process
I5102_RS29905	COG2181	nitrate reductase activity
I5102_RS29925	COG3655	Transcriptional regulator
I5102_RS29965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I5102_RS29965	COG1017	nitric oxide dioxygenase activity
I5102_RS30050	COG0583	DNA-binding transcription factor activity
I5102_RS30060	COG2391	methyltransferase activity
I5102_RS30085	COG5016	pyruvate
I5102_RS30085	COG0511	ligase activity, forming carbon-carbon bonds
I5102_RS30090	COG0439	Biotin carboxylase
I5102_RS30095	COG0583	DNA-binding transcription factor activity
I5102_RS30110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I5102_RS30115	COG0826	peptidase U32
I5102_RS30135	COG0210	DNA helicase
I5102_RS30145	COG0427	acetyl-CoA hydrolase
I5102_RS30160	COG0438	transferase activity, transferring glycosyl groups
I5102_RS30205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I5102_RS30210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I5102_RS30210	COG2755	lipolytic protein G-D-S-L family