locus-tag	class	description
HW07_RS00035	COG2010	Cytochrome c
HW07_RS00050	COG2818	Glycosylase
HW07_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HW07_RS00080	COG0569	domain protein
HW07_RS00100	COG1652	LysM domain
HW07_RS00105	COG0758	DNA mediated transformation
HW07_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW07_RS00155	COG3119	arylsulfatase activity
HW07_RS00160	COG0583	DNA-binding transcription factor activity
HW07_RS00195	COG3360	Dodecin
HW07_RS00235	COG3174	membrane
HW07_RS00280	COG0367	asparagine synthase
HW07_RS00300	COG0583	DNA-binding transcription factor activity
HW07_RS00315	COG1764	response to oxidative stress
HW07_RS00350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HW07_RS00355	COG0339	signal peptide processing
HW07_RS00360	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HW07_RS00375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HW07_RS00390	COG2815	serine threonine protein kinase
HW07_RS00390	COG0515	serine threonine protein kinase
HW07_RS00395	COG0631	protein serine/threonine phosphatase activity
HW07_RS00410	COG1360	Flagellar Motor Protein
HW07_RS00540	COG0659	secondary active sulfate transmembrane transporter activity
HW07_RS00555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HW07_RS00560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HW07_RS00565	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HW07_RS00605	COG2153	protein acetylation
HW07_RS00645	COG0583	DNA-binding transcription factor activity
HW07_RS00670	COG2824	Alkylphosphonate utilization operon protein PhnA
HW07_RS00700	COG0402	S-adenosylhomocysteine deaminase activity
HW07_RS00710	COG3845	ABC transporter
HW07_RS00715	COG4603	Belongs to the binding-protein-dependent transport system permease family
HW07_RS00720	COG1079	Belongs to the binding-protein-dependent transport system permease family
HW07_RS00795	COG0583	DNA-binding transcription factor activity
HW07_RS00800	COG3485	protocatechuate 3,4-dioxygenase
HW07_RS00805	COG3485	protocatechuate 3,4-dioxygenase
HW07_RS00815	COG1414	Transcriptional regulator
HW07_RS00830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS00835	COG0583	DNA-binding transcription factor activity
HW07_RS00870	COG2233	PERMEase
HW07_RS00875	COG1309	transcriptional regulator
HW07_RS00910	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HW07_RS00930	COG2198	Histidine kinase
HW07_RS00930	COG0643	Histidine kinase
HW07_RS00935	COG0745	RESPONSE REGULATOR receiver
HW07_RS00945	COG0583	DNA-binding transcription factor activity
HW07_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS00960	COG1116	anion transmembrane transporter activity
HW07_RS00965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW07_RS00970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS01015	COG2175	clavaminate synthase activity
HW07_RS01090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HW07_RS01125	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS01130	COG1113	amino acid transport
HW07_RS01145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW07_RS01150	COG0235	Class ii aldolase
HW07_RS01155	COG1396	sequence-specific DNA binding
HW07_RS01160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HW07_RS01165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HW07_RS01175	COG0477	Major facilitator Superfamily
HW07_RS01185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW07_RS01190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW07_RS01195	COG0583	DNA-binding transcription factor activity
HW07_RS01215	COG0673	inositol 2-dehydrogenase activity
HW07_RS01235	COG2271	Major facilitator Superfamily
HW07_RS01245	COG1309	transcriptional regulator
HW07_RS01250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HW07_RS01260	COG0477	Major facilitator Superfamily
HW07_RS01280	COG2239	Acts as a magnesium transporter
HW07_RS01425	COG0582	viral genome integration into host DNA
HW07_RS01515	COG0745	RESPONSE REGULATOR receiver
HW07_RS01525	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW07_RS01540	COG0583	DNA-binding transcription factor activity
HW07_RS01545	COG2807	transmembrane transport
HW07_RS01565	COG0501	Belongs to the peptidase M48B family
HW07_RS01585	COG4208	sulfate ABC transporter
HW07_RS01595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HW07_RS01615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW07_RS01630	COG2199	diguanylate cyclase activity
HW07_RS01655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HW07_RS01660	COG0174	glutamine synthetase
HW07_RS01665	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HW07_RS01670	COG0174	glutamine synthetase
HW07_RS01690	COG3842	ATPase activity
HW07_RS01695	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW07_RS01700	COG1177	transmembrane transport
HW07_RS01755	COG0765	amino acid transport
HW07_RS01770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HW07_RS01775	COG0277	FAD linked oxidase domain protein
HW07_RS01780	COG0179	Fumarylacetoacetate (FAA) hydrolase
HW07_RS01790	COG3111	PFAM Bacterial OB fold (BOF) protein
HW07_RS01800	COG0531	amino acid
HW07_RS01805	COG2182	Extracellular solute-binding protein
HW07_RS01810	COG1177	transmembrane transport
HW07_RS01820	COG3842	ATPase activity
HW07_RS01830	COG3204	pilus organization
HW07_RS01835	COG2234	aminopeptidase activity
HW07_RS01855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HW07_RS01865	COG0702	epimerase
HW07_RS01905	COG0730	response to heat
HW07_RS01940	COG0584	glycerophosphoryl diester phosphodiesterase
HW07_RS01960	COG0622	Phosphoesterase
HW07_RS01965	COG2233	PERMEase
HW07_RS01980	COG0693	protein deglycase activity
HW07_RS02015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW07_RS02025	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HW07_RS02050	COG0429	hydrolase of the alpha beta-hydrolase fold
HW07_RS02060	COG0742	ribosomal rna small subunit methyltransferase
HW07_RS02065	COG0612	Peptidase, M16
HW07_RS02070	COG0612	Peptidase, M16
HW07_RS02075	COG0552	protein localization to endoplasmic reticulum
HW07_RS02080	COG2884	Cell division ATP-binding protein ftsE
HW07_RS02085	COG2177	Part of the ABC transporter FtsEX involved in
HW07_RS02105	COG2363	Small membrane protein
HW07_RS02140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HW07_RS02155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW07_RS02155	COG2813	Specifically methylates the guanine in position
HW07_RS02165	COG1160	GTP binding
HW07_RS02170	COG1872	DUF167
HW07_RS02215	COG0626	cystathionine gamma-synthase activity
HW07_RS02280	COG0643	Histidine kinase
HW07_RS02280	COG0784	Response regulator, receiver
HW07_RS02280	COG2198	Histidine kinase
HW07_RS02310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HW07_RS02330	COG3038	cytochrome b561
HW07_RS02360	COG0513	Belongs to the DEAD box helicase family
HW07_RS02370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HW07_RS02375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW07_RS02400	COG1309	transcriptional regulator
HW07_RS02405	COG0402	S-adenosylhomocysteine deaminase activity
HW07_RS02410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HW07_RS02445	COG1953	Uracil, thiamine, allantoin
HW07_RS02460	COG1960	acyl-CoA dehydrogenase activity
HW07_RS02465	COG0583	DNA-binding transcription factor activity
HW07_RS02475	COG0306	phosphate transporter
HW07_RS02485	COG0330	HflC and HflK could
HW07_RS02495	COG1289	transmembrane transporter activity
HW07_RS02500	COG0513	Belongs to the DEAD box helicase family
HW07_RS02510	COG4067	protein conserved in archaea
HW07_RS02510	COG0189	ligase activity
HW07_RS02520	COG0477	Major facilitator Superfamily
HW07_RS02530	COG0542	response to heat
HW07_RS02540	COG0204	Acyl-transferase
HW07_RS02550	COG0745	RESPONSE REGULATOR receiver
HW07_RS02555	COG2205	protein histidine kinase activity
HW07_RS02560	COG4452	Inner membrane protein CreD
HW07_RS02595	COG4774	siderophore transport
HW07_RS02600	COG3712	iron ion homeostasis
HW07_RS02605	COG1595	DNA-templated transcription, initiation
HW07_RS02610	COG0625	glutathione transferase activity
HW07_RS02620	COG1309	transcriptional regulator
HW07_RS02625	COG1953	Uracil, thiamine, allantoin
HW07_RS02645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HW07_RS02680	COG2005	Transcriptional regulator
HW07_RS02680	COG3585	molybdate ion transport
HW07_RS02685	COG5544	Lipoprotein
HW07_RS02690	COG1040	competence protein
HW07_RS02710	COG0511	ligase activity, forming carbon-carbon bonds
HW07_RS02725	COG1984	allophanate hydrolase subunit 2
HW07_RS02740	COG3121	Chaperone
HW07_RS02755	COG1073	alpha beta
HW07_RS02755	COG2226	methyltransferase
HW07_RS02775	COG1960	acyl-CoA dehydrogenase activity
HW07_RS02780	COG1960	acyl-CoA dehydrogenase activity
HW07_RS02785	COG1960	acyl-CoA dehydrogenase activity
HW07_RS02795	COG1648	precorrin-2 dehydrogenase activity
HW07_RS02795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HW07_RS02880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HW07_RS02885	COG0583	DNA-binding transcription factor activity
HW07_RS02890	COG2258	MOSC domain
HW07_RS02900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HW07_RS02925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS02935	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HW07_RS02990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW07_RS02995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HW07_RS03005	COG3622	Belongs to the hyi family
HW07_RS03010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HW07_RS03050	COG2081	HI0933 family
HW07_RS03055	COG1451	nucleotide metabolic process
HW07_RS03065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HW07_RS03070	COG3152	Membrane
HW07_RS03075	COG4977	sequence-specific DNA binding
HW07_RS03075	COG1917	Cupin 2, conserved barrel domain protein
HW07_RS03080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW07_RS03175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HW07_RS03195	COG2719	SpoVR family
HW07_RS03205	COG2766	serine protein kinase
HW07_RS03255	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HW07_RS03270	COG2197	response regulator
HW07_RS03280	COG3842	ATPase activity
HW07_RS03290	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW07_RS03300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HW07_RS03325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW07_RS03340	COG3179	chitinase
HW07_RS03460	COG1765	OsmC-like protein
HW07_RS03475	COG0537	adenosine 5'-monophosphoramidase activity
HW07_RS03500	COG1981	membrane
HW07_RS03530	COG0739	heme binding
HW07_RS03695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HW07_RS03820	COG2814	Major facilitator Superfamily
HW07_RS03845	COG1021	2,3-dihydroxybenzoate-AMP ligase
HW07_RS03855	COG2226	methyltransferase
HW07_RS03855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW07_RS03855	COG3433	isochorismatase activity
HW07_RS03860	COG3433	isochorismatase activity
HW07_RS03860	COG2226	methyltransferase
HW07_RS03860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW07_RS03870	COG2375	cellular response to nickel ion
HW07_RS03870	COG1132	(ABC) transporter
HW07_RS03960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS03965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS03975	COG2706	6-phosphogluconolactonase activity
HW07_RS03995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW07_RS04000	COG1960	acyl-CoA dehydrogenase activity
HW07_RS04010	COG4191	Histidine kinase
HW07_RS04015	COG4566	intracellular signal transduction
HW07_RS04020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS04025	COG0765	amino acid transport
HW07_RS04030	COG0765	amino acid transport
HW07_RS04050	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS04055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW07_RS04060	COG2271	Major facilitator Superfamily
HW07_RS04110	COG2226	methyltransferase
HW07_RS04120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW07_RS04135	COG0251	oxidation-reduction process
HW07_RS04145	COG0693	protein deglycase activity
HW07_RS04155	COG1959	2 iron, 2 sulfur cluster binding
HW07_RS04185	COG0154	amidase activity
HW07_RS04195	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS04200	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW07_RS04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW07_RS04210	COG4592	Periplasmic binding protein
HW07_RS04215	COG1120	ATPase activity
HW07_RS04225	COG1629	transport
HW07_RS04225	COG4774	siderophore transport
HW07_RS04230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW07_RS04235	COG4991	sh3 domain protein
HW07_RS04240	COG1063	alcohol dehydrogenase
HW07_RS04250	COG0022	dehydrogenase e1 component
HW07_RS04255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HW07_RS04260	COG3199	ATP-NAD kinase
HW07_RS04270	COG3284	Transcriptional regulator
HW07_RS04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS04330	COG2814	Major facilitator Superfamily
HW07_RS04335	COG1846	Transcriptional regulator
HW07_RS04345	COG3278	Belongs to the heme-copper respiratory oxidase family
HW07_RS04350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW07_RS04360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW07_RS04375	COG3971	2-oxopent-4-enoate hydratase activity
HW07_RS04380	COG2271	Major facilitator Superfamily
HW07_RS04390	COG3384	dioxygenase
HW07_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS04435	COG1611	Belongs to the LOG family
HW07_RS04480	COG0583	DNA-binding transcription factor activity
HW07_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS04505	COG1063	alcohol dehydrogenase
HW07_RS04510	COG2271	Major facilitator Superfamily
HW07_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS04550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HW07_RS04565	COG3121	Chaperone
HW07_RS04570	COG3188	usher protein
HW07_RS04575	COG3121	Chaperone
HW07_RS04590	COG2197	response regulator
HW07_RS04630	COG0531	amino acid
HW07_RS04650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HW07_RS04660	COG3047	cAMP biosynthetic process
HW07_RS04690	COG3118	belongs to the thioredoxin family
HW07_RS04695	COG2264	protein methyltransferase activity
HW07_RS04715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HW07_RS04715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HW07_RS04740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HW07_RS04745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HW07_RS04755	COG3577	Aspartyl protease
HW07_RS04780	COG0142	geranyltranstransferase activity
HW07_RS04790	COG4948	Mandelate Racemase Muconate Lactonizing
HW07_RS04810	COG1131	(ABC) transporter
HW07_RS04815	COG5002	protein histidine kinase activity
HW07_RS04835	COG0745	RESPONSE REGULATOR receiver
HW07_RS04845	COG3228	Belongs to the MtfA family
HW07_RS04850	COG0586	Pfam SNARE associated Golgi protein
HW07_RS04865	COG0456	acetyltransferase
HW07_RS04875	COG4303	Ethanolamine ammonia lyase large subunit
HW07_RS04880	COG0531	amino acid
HW07_RS04890	COG3284	Transcriptional regulator
HW07_RS04895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HW07_RS04910	COG0702	epimerase
HW07_RS04930	COG1346	cytolysis
HW07_RS04940	COG0586	Pfam SNARE associated Golgi protein
HW07_RS04980	COG0768	penicillin binding
HW07_RS04985	COG0772	Belongs to the SEDS family
HW07_RS04990	COG2951	lytic endotransglycosylase activity
HW07_RS05000	COG1686	Belongs to the peptidase S11 family
HW07_RS05030	COG2951	lytic endotransglycosylase activity
HW07_RS05065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HW07_RS05075	COG4535	Mg2 and Co2 transporter CorC
HW07_RS05085	COG1702	phosphate starvation-inducible protein PhoH
HW07_RS05115	COG0351	phosphomethylpyrimidine kinase
HW07_RS05120	COG0784	Response regulator, receiver
HW07_RS05120	COG2198	Histidine kinase
HW07_RS05120	COG2205	protein histidine kinase activity
HW07_RS05130	COG1960	acyl-CoA dehydrogenase activity
HW07_RS05140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HW07_RS05180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HW07_RS05190	COG1643	Atp-dependent helicase
HW07_RS05235	COG3416	Protein conserved in bacteria
HW07_RS05245	COG0513	Belongs to the DEAD box helicase family
HW07_RS05260	COG2197	response regulator
HW07_RS05265	COG2199	diguanylate cyclase activity
HW07_RS05265	COG2200	EAL domain
HW07_RS05265	COG2202	Pas domain
HW07_RS05270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS05270	COG2205	protein histidine kinase activity
HW07_RS05290	COG1946	Acyl-CoA thioesterase
HW07_RS05310	COG4521	taurine ABC transporter
HW07_RS05320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW07_RS05325	COG2175	clavaminate synthase activity
HW07_RS05330	COG1297	OPT oligopeptide transporter protein
HW07_RS05335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW07_RS05350	COG1271	oxidase subunit
HW07_RS05355	COG1294	oxidase, subunit
HW07_RS05365	COG2207	Transcriptional regulator
HW07_RS05375	COG0183	Belongs to the thiolase family
HW07_RS05380	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS05415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HW07_RS05425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HW07_RS05435	COG0521	Mo-molybdopterin cofactor biosynthetic process
HW07_RS05440	COG0303	'Molybdopterin
HW07_RS05445	COG0826	peptidase U32
HW07_RS05450	COG0826	peptidase U32
HW07_RS05455	COG3154	lipid carrier protein
HW07_RS05505	COG4772	TonB-dependent receptor
HW07_RS05510	COG3712	iron ion homeostasis
HW07_RS05515	COG1595	DNA-templated transcription, initiation
HW07_RS05525	COG0697	spore germination
HW07_RS05535	COG0583	DNA-binding transcription factor activity
HW07_RS05555	COG1566	PFAM secretion protein HlyD family protein
HW07_RS05610	COG0300	oxidoreductase activity
HW07_RS05615	COG2226	methyltransferase
HW07_RS05630	COG2197	response regulator
HW07_RS05635	COG3850	Histidine kinase
HW07_RS05645	COG2223	nitrite transmembrane transporter activity
HW07_RS05650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HW07_RS05655	COG1140	nitrate reductase beta subunit
HW07_RS05660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HW07_RS05665	COG2181	nitrate reductase activity
HW07_RS05670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW07_RS05680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS05710	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS05720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS05785	COG0583	DNA-binding transcription factor activity
HW07_RS05820	COG0490	domain, Protein
HW07_RS05820	COG0471	metal ion transport
HW07_RS05825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HW07_RS05830	COG4120	Belongs to the binding-protein-dependent transport system permease family
HW07_RS05875	COG0795	lipopolysaccharide-transporting ATPase activity
HW07_RS05880	COG0795	lipopolysaccharide-transporting ATPase activity
HW07_RS05890	COG2200	EAL domain
HW07_RS05910	COG1862	Preprotein translocase
HW07_RS05925	COG3134	Outer membrane lipoprotein
HW07_RS05940	COG1045	serine acetyltransferase
HW07_RS06030	COG0436	Aminotransferase
HW07_RS06045	COG0667	Aldo Keto reductase
HW07_RS06085	COG0739	heme binding
HW07_RS06095	COG2847	Copper chaperone PCu(A)C
HW07_RS06105	COG1335	isochorismatase
HW07_RS06120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HW07_RS06130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HW07_RS06135	COG0583	DNA-binding transcription factor activity
HW07_RS06185	COG2132	Multicopper oxidase
HW07_RS06190	COG0590	tRNA wobble adenosine to inosine editing
HW07_RS06235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HW07_RS06235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HW07_RS06240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HW07_RS06245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HW07_RS06250	COG2188	Transcriptional regulator
HW07_RS06290	COG0477	Major facilitator Superfamily
HW07_RS06295	COG4536	flavin adenine dinucleotide binding
HW07_RS06305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HW07_RS06330	COG1607	acyl-coa hydrolase
HW07_RS06350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HW07_RS06375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW07_RS06400	COG2255	four-way junction helicase activity
HW07_RS06415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HW07_RS06425	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS06470	COG2197	response regulator
HW07_RS06475	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HW07_RS06495	COG0477	Major facilitator Superfamily
HW07_RS06530	COG2203	Gaf domain
HW07_RS06530	COG4251	negative regulation of phosphorylation
HW07_RS06530	COG5001	Diguanylate cyclase
HW07_RS06530	COG3706	GGDEF domain
HW07_RS06565	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HW07_RS06565	COG1073	alpha beta
HW07_RS06565	COG3064	Membrane
HW07_RS06580	COG2885	chlorophyll binding
HW07_RS06595	COG0789	Transcriptional regulator
HW07_RS06615	COG1214	PFAM Peptidase M22, glycoprotease
HW07_RS06625	COG1801	Protein of unknown function DUF72
HW07_RS06630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HW07_RS06655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS06700	COG2166	iron-sulfur cluster assembly
HW07_RS06720	COG1393	Belongs to the ArsC family
HW07_RS06740	COG0025	NhaP-type Na H and K H
HW07_RS06745	COG0436	Aminotransferase
HW07_RS06755	COG0024	Methionine aminopeptidase
HW07_RS06835	COG1115	amino acid carrier protein
HW07_RS06885	COG2391	methyltransferase activity
HW07_RS06890	COG0583	DNA-binding transcription factor activity
HW07_RS06895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HW07_RS06900	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HW07_RS06955	COG1546	Belongs to the CinA family
HW07_RS06975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HW07_RS06980	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HW07_RS06985	COG3530	Putative quorum-sensing-regulated virulence factor
HW07_RS07000	COG1177	transmembrane transport
HW07_RS07005	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW07_RS07015	COG3148	PFAM DTW domain containing protein
HW07_RS07035	COG0069	glutamate synthase activity
HW07_RS07060	COG0531	amino acid
HW07_RS07065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW07_RS07065	COG2169	Transcriptional regulator
HW07_RS07070	COG0477	Major facilitator Superfamily
HW07_RS07080	COG0583	DNA-binding transcription factor activity
HW07_RS07085	COG1960	acyl-CoA dehydrogenase activity
HW07_RS07090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW07_RS07095	COG1024	Enoyl-CoA hydratase
HW07_RS07100	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW07_RS07105	COG0183	Belongs to the thiolase family
HW07_RS07115	COG0583	DNA-binding transcription factor activity
HW07_RS07155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HW07_RS07205	COG2814	Major facilitator Superfamily
HW07_RS07245	COG0583	DNA-binding transcription factor activity
HW07_RS07255	COG0084	hydrolase, TatD family'
HW07_RS07260	COG1609	Transcriptional regulator
HW07_RS07270	COG1105	Belongs to the carbohydrate kinase PfkB family
HW07_RS07275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HW07_RS07275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HW07_RS07275	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HW07_RS07390	COG3842	ATPase activity
HW07_RS07410	COG0243	molybdopterin cofactor binding
HW07_RS07415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HW07_RS07420	COG2223	nitrite transmembrane transporter activity
HW07_RS07435	COG0450	alkyl hydroperoxide reductase
HW07_RS07465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS07500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HW07_RS07505	COG2264	protein methyltransferase activity
HW07_RS07515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HW07_RS07570	COG0489	protein tyrosine kinase activity
HW07_RS07620	COG0791	NLP P60 protein
HW07_RS07640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HW07_RS07645	COG0668	transmembrane transport
HW07_RS07650	COG0477	Major facilitator Superfamily
HW07_RS07655	COG0513	Belongs to the DEAD box helicase family
HW07_RS07675	COG2205	protein histidine kinase activity
HW07_RS07675	COG0784	Response regulator, receiver
HW07_RS07675	COG5002	protein histidine kinase activity
HW07_RS07680	COG1363	Peptidase, m42
HW07_RS07685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HW07_RS07685	COG0189	ligase activity
HW07_RS07690	COG0367	asparagine synthase
HW07_RS07720	COG0183	Belongs to the thiolase family
HW07_RS07740	COG0450	alkyl hydroperoxide reductase
HW07_RS07745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS07750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW07_RS07760	COG0431	NADPH-dependent FMN reductase
HW07_RS07765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS07775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW07_RS07800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HW07_RS07825	COG0583	DNA-binding transcription factor activity
HW07_RS07830	COG1380	Effector of murein hydrolase LrgA
HW07_RS07835	COG1346	cytolysis
HW07_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS07860	COG1024	Enoyl-CoA hydratase
HW07_RS07870	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HW07_RS07915	COG0508	dehydrogenase complex catalyzes the overall conversion of
HW07_RS07955	COG1629	transport
HW07_RS08010	COG0583	DNA-binding transcription factor activity
HW07_RS08085	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HW07_RS08090	COG3639	organic phosphonate transmembrane transporter activity
HW07_RS08095	COG2188	Transcriptional regulator
HW07_RS08100	COG3624	Phosphonate C-P lyase system protein PhnG
HW07_RS08110	COG3626	phosphonate metabolism
HW07_RS08115	COG3627	carbon phosphorus lyase activity
HW07_RS08120	COG4107	phosphonate C-P lyase system protein PhnK
HW07_RS08125	COG4778	phosphonate C-P lyase system protein PhnL
HW07_RS08130	COG3454	Phosphonate metabolism
HW07_RS08140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HW07_RS08215	COG0697	spore germination
HW07_RS08240	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HW07_RS08260	COG0784	Response regulator, receiver
HW07_RS08260	COG0835	chemotaxis
HW07_RS08275	COG0745	RESPONSE REGULATOR receiver
HW07_RS08285	COG0514	ATP-dependent DNA helicase (RecQ)
HW07_RS08290	COG4251	negative regulation of phosphorylation
HW07_RS08290	COG2203	Gaf domain
HW07_RS08290	COG5001	Diguanylate cyclase
HW07_RS08290	COG3706	GGDEF domain
HW07_RS08315	COG1752	Esterase of the alpha-beta hydrolase superfamily
HW07_RS08355	COG2124	cytochrome p450
HW07_RS08360	COG4221	oxidoreductase activity
HW07_RS08405	COG0583	DNA-binding transcription factor activity
HW07_RS08440	COG3639	organic phosphonate transmembrane transporter activity
HW07_RS08450	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HW07_RS08455	COG2084	Dehydrogenase
HW07_RS08470	COG0589	response to stress
HW07_RS08510	COG2814	Major facilitator Superfamily
HW07_RS08515	COG2030	dehydratase
HW07_RS08520	COG2267	carboxylic ester hydrolase activity
HW07_RS08525	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS08530	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS08545	COG1643	Atp-dependent helicase
HW07_RS08555	COG0537	adenosine 5'-monophosphoramidase activity
HW07_RS08610	COG1595	DNA-templated transcription, initiation
HW07_RS08685	COG1201	RNA secondary structure unwinding
HW07_RS08690	COG2205	protein histidine kinase activity
HW07_RS08705	COG4772	TonB-dependent receptor
HW07_RS08720	COG2076	Multidrug Resistance protein
HW07_RS08725	COG0385	Bile acid
HW07_RS08775	COG2200	EAL domain
HW07_RS08785	COG0604	alcohol dehydrogenase
HW07_RS08785	COG3321	synthase
HW07_RS08790	COG0560	Phosphoserine phosphatase
HW07_RS08805	COG1176	ABC-type spermidine putrescine transport system, permease component I
HW07_RS08835	COG0564	pseudouridine synthase activity
HW07_RS08845	COG2894	cell division
HW07_RS08855	COG1560	Kdo2-lipid A biosynthetic process
HW07_RS08870	COG2853	Lipoprotein
HW07_RS08890	COG3162	membrane
HW07_RS08895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW07_RS08925	COG1132	(ABC) transporter
HW07_RS08960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HW07_RS08975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HW07_RS08975	COG0438	transferase activity, transferring glycosyl groups
HW07_RS09005	COG1127	ABC transporter
HW07_RS09010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HW07_RS09015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HW07_RS09020	COG0727	PFAM Uncharacterised protein family (UPF0153)
HW07_RS09025	COG0778	Nitroreductase
HW07_RS09045	COG0745	RESPONSE REGULATOR receiver
HW07_RS09055	COG2350	Protein conserved in bacteria
HW07_RS09065	COG0613	PHP domain protein
HW07_RS09070	COG0009	L-threonylcarbamoyladenylate synthase
HW07_RS09075	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HW07_RS09080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HW07_RS09130	COG1175	transmembrane transport
HW07_RS09135	COG0395	ABC-type sugar transport system, permease component
HW07_RS09140	COG3842	ATPase activity
HW07_RS09155	COG0676	glucose-6-phosphate 1-epimerase activity
HW07_RS09200	COG0786	glutamate:sodium symporter activity
HW07_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS09230	COG0402	S-adenosylhomocysteine deaminase activity
HW07_RS09260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HW07_RS09325	COG1215	transferase activity, transferring glycosyl groups
HW07_RS09330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HW07_RS09345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HW07_RS09385	COG0583	DNA-binding transcription factor activity
HW07_RS09420	COG0596	Alpha beta hydrolase
HW07_RS09425	COG0800	Aldolase
HW07_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS09460	COG0583	DNA-binding transcription factor activity
HW07_RS09465	COG0251	oxidation-reduction process
HW07_RS09485	COG2226	methyltransferase
HW07_RS09525	COG0285	dihydrofolate synthase activity
HW07_RS09530	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HW07_RS09535	COG1286	toxin biosynthetic process
HW07_RS09635	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW07_RS09635	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS09660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HW07_RS09670	COG3139	Protein of unknown function (DUF1315)
HW07_RS09680	COG0308	aminopeptidase N
HW07_RS09715	COG0745	RESPONSE REGULATOR receiver
HW07_RS09750	COG0714	Associated with various cellular activities
HW07_RS09770	COG1335	isochorismatase
HW07_RS09780	COG2342	PFAM TM1410 hypothetical-related protein
HW07_RS09805	COG0297	glycogen (starch) synthase activity
HW07_RS09855	COG3130	regulation of translation
HW07_RS09870	COG2027	D-alanyl-D-alanine carboxypeptidase
HW07_RS09875	COG3171	Protein conserved in bacteria
HW07_RS09880	COG2197	response regulator
HW07_RS09885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS09885	COG2205	protein histidine kinase activity
HW07_RS09915	COG0004	ammonium transporteR
HW07_RS09925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW07_RS09935	COG0625	glutathione transferase activity
HW07_RS09940	COG1309	transcriptional regulator
HW07_RS09970	COG0521	Mo-molybdopterin cofactor biosynthetic process
HW07_RS09990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HW07_RS09995	COG1070	Carbohydrate kinase
HW07_RS10015	COG0741	lytic transglycosylase activity
HW07_RS10020	COG0488	(ABC) transporter
HW07_RS10030	COG0589	response to stress
HW07_RS10110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HW07_RS10120	COG1113	amino acid transport
HW07_RS10155	COG1477	protein flavinylation
HW07_RS10170	COG0584	glycerophosphoryl diester phosphodiesterase
HW07_RS10185	COG4591	ABC-type transport system involved in lipoprotein release permease component
HW07_RS10205	COG2333	competence protein COMEC
HW07_RS10205	COG0658	competence protein
HW07_RS10210	COG0811	peptide transport
HW07_RS10215	COG0848	biopolymer transport protein
HW07_RS10235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HW07_RS10245	COG1530	ribonuclease E activity
HW07_RS10260	COG0546	phosphoglycolate phosphatase activity
HW07_RS10265	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HW07_RS10265	COG0616	signal peptide processing
HW07_RS10275	COG1399	metal-binding, possibly nucleic acid-binding protein
HW07_RS10305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HW07_RS10315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HW07_RS10335	COG0084	hydrolase, TatD family'
HW07_RS10420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HW07_RS10435	COG0183	Belongs to the thiolase family
HW07_RS10450	COG2233	PERMEase
HW07_RS10460	COG3038	cytochrome b561
HW07_RS10475	COG2814	Major facilitator Superfamily
HW07_RS10480	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS10485	COG1309	transcriptional regulator
HW07_RS10520	COG4160	amino acid transport
HW07_RS10525	COG4215	(ABC) transporter
HW07_RS10530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS10535	COG1473	amidohydrolase
HW07_RS10540	COG0583	DNA-binding transcription factor activity
HW07_RS10545	COG0840	transmembrane signaling receptor activity
HW07_RS10575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW07_RS10585	COG1120	ATPase activity
HW07_RS10615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW07_RS10645	COG2885	chlorophyll binding
HW07_RS10645	COG3047	cAMP biosynthetic process
HW07_RS10650	COG2197	response regulator
HW07_RS10660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW07_RS10665	COG1595	DNA-templated transcription, initiation
HW07_RS10680	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS10695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HW07_RS10700	COG1960	acyl-CoA dehydrogenase activity
HW07_RS10705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HW07_RS10720	COG1309	transcriptional regulator
HW07_RS10750	COG0583	DNA-binding transcription factor activity
HW07_RS10760	COG0583	DNA-binding transcription factor activity
HW07_RS10770	COG0714	Associated with various cellular activities
HW07_RS10815	COG0084	hydrolase, TatD family'
HW07_RS10820	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HW07_RS10825	COG2259	Doxx family
HW07_RS10840	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HW07_RS10855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HW07_RS10860	COG4181	ATPase activity
HW07_RS10900	COG1764	response to oxidative stress
HW07_RS10905	COG1846	Transcriptional regulator
HW07_RS10910	COG0583	DNA-binding transcription factor activity
HW07_RS10920	COG0583	DNA-binding transcription factor activity
HW07_RS10930	COG3214	Protein conserved in bacteria
HW07_RS10935	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HW07_RS10945	COG1024	Enoyl-CoA hydratase
HW07_RS10955	COG3384	dioxygenase
HW07_RS10995	COG2866	Carboxypeptidase
HW07_RS11010	COG0436	Aminotransferase
HW07_RS11020	COG0386	Belongs to the glutathione peroxidase family
HW07_RS11025	COG1846	Transcriptional regulator
HW07_RS11030	COG5002	protein histidine kinase activity
HW07_RS11030	COG2205	protein histidine kinase activity
HW07_RS11030	COG0784	Response regulator, receiver
HW07_RS11035	COG2255	four-way junction helicase activity
HW07_RS11040	COG1956	GAF domain-containing protein
HW07_RS11045	COG0625	glutathione transferase activity
HW07_RS11140	COG0625	glutathione transferase activity
HW07_RS11145	COG1131	(ABC) transporter
HW07_RS11150	COG0842	Transport permease protein
HW07_RS11195	COG2188	Transcriptional regulator
HW07_RS11205	COG2853	Lipoprotein
HW07_RS11215	COG0745	RESPONSE REGULATOR receiver
HW07_RS11235	COG1335	isochorismatase
HW07_RS11290	COG3655	Transcriptional regulator
HW07_RS11335	COG2116	formate transmembrane transporter activity
HW07_RS11340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS11395	COG1051	belongs to the nudix hydrolase family
HW07_RS11405	COG1024	Enoyl-CoA hydratase
HW07_RS11405	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW07_RS11415	COG2837	iron assimilation
HW07_RS11500	COG1238	metal cluster binding
HW07_RS11510	COG1295	ribonuclease BN
HW07_RS11540	COG0024	Methionine aminopeptidase
HW07_RS11620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HW07_RS11635	COG2826	transposase and inactivated derivatives, IS30 family
HW07_RS11650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW07_RS11680	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HW07_RS11680	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HW07_RS11690	COG0542	response to heat
HW07_RS11725	COG0789	Transcriptional regulator
HW07_RS11735	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS11735	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW07_RS11740	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HW07_RS11745	COG0243	molybdopterin cofactor binding
HW07_RS11770	COG1280	lysine exporter protein (LysE YggA)
HW07_RS11785	COG0542	response to heat
HW07_RS11860	COG1607	acyl-coa hydrolase
HW07_RS11865	COG1959	2 iron, 2 sulfur cluster binding
HW07_RS11875	COG2819	hydrolase of the alpha beta superfamily
HW07_RS11920	COG0583	DNA-binding transcription factor activity
HW07_RS11930	COG4106	trans-aconitate 2-methyltransferase activity
HW07_RS11940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW07_RS11945	COG1459	type II secretion system
HW07_RS11955	COG2165	general secretion pathway protein
HW07_RS11995	COG0720	synthase
HW07_RS12000	COG3604	Transcriptional regulator
HW07_RS12060	COG0840	transmembrane signaling receptor activity
HW07_RS12065	COG2056	Na+-H+ antiporter family
HW07_RS12080	COG2226	methyltransferase
HW07_RS12180	COG2153	protein acetylation
HW07_RS12185	COG2850	peptidyl-arginine hydroxylation
HW07_RS12225	COG1278	Cold shock
HW07_RS12235	COG0542	response to heat
HW07_RS12240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HW07_RS12255	COG0492	ferredoxin-NADP+ reductase activity
HW07_RS12270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HW07_RS12285	COG0435	Glutathione S-transferase
HW07_RS12290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HW07_RS12295	COG2920	part of a sulfur-relay system
HW07_RS12335	COG0583	DNA-binding transcription factor activity
HW07_RS12340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW07_RS12345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS12355	COG1960	acyl-CoA dehydrogenase activity
HW07_RS12360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS12370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS12375	COG3424	synthase
HW07_RS12385	COG0583	DNA-binding transcription factor activity
HW07_RS12415	COG1960	acyl-CoA dehydrogenase activity
HW07_RS12420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW07_RS12430	COG1309	transcriptional regulator
HW07_RS12440	COG1131	(ABC) transporter
HW07_RS12445	COG0842	Transport permease protein
HW07_RS12450	COG0842	Transport permease protein
HW07_RS12475	COG2197	response regulator
HW07_RS12480	COG4771	TonB-dependent receptor
HW07_RS12535	COG2205	protein histidine kinase activity
HW07_RS12535	COG0784	Response regulator, receiver
HW07_RS12535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS12535	COG2198	Histidine kinase
HW07_RS12555	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW07_RS12570	COG1522	sequence-specific DNA binding
HW07_RS12600	COG4191	Histidine kinase
HW07_RS12650	COG0419	ATPase involved in DNA repair
HW07_RS12655	COG1674	ftsk spoiiie
HW07_RS12665	COG3723	Recombinational DNA repair protein, rece pathway
HW07_RS12685	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HW07_RS12775	COG5484	DNA packaging
HW07_RS12775	COG3728	DNA packaging
HW07_RS12905	COG3179	chitinase
HW07_RS12925	COG2135	peptidase activity
HW07_RS12950	COG2203	Gaf domain
HW07_RS12950	COG3706	GGDEF domain
HW07_RS12950	COG4251	negative regulation of phosphorylation
HW07_RS12950	COG5001	Diguanylate cyclase
HW07_RS12960	COG0659	secondary active sulfate transmembrane transporter activity
HW07_RS12995	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS13005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HW07_RS13015	COG0183	Belongs to the thiolase family
HW07_RS13020	COG1960	acyl-CoA dehydrogenase activity
HW07_RS13070	COG0729	surface antigen
HW07_RS13080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HW07_RS13085	COG2267	carboxylic ester hydrolase activity
HW07_RS13090	COG2453	phosphatase
HW07_RS13090	COG0671	phosphoesterase, PA-phosphatase related
HW07_RS13105	COG4589	Belongs to the CDS family
HW07_RS13110	COG0667	Aldo Keto reductase
HW07_RS13120	COG1115	amino acid carrier protein
HW07_RS13130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HW07_RS13160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS13165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS13170	COG1538	Outer membrane efflux protein
HW07_RS13230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HW07_RS13230	COG0543	2 iron, 2 sulfur cluster binding
HW07_RS13235	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HW07_RS13240	COG4638	Rieske (2fe-2S)
HW07_RS13265	COG4948	Mandelate Racemase Muconate Lactonizing
HW07_RS13275	COG3485	protocatechuate 3,4-dioxygenase
HW07_RS13310	COG2807	transmembrane transport
HW07_RS13315	COG0590	tRNA wobble adenosine to inosine editing
HW07_RS13330	COG2318	DinB family
HW07_RS13390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW07_RS13395	COG2863	cytochrome
HW07_RS13400	COG3258	Cytochrome c
HW07_RS13405	COG0642	Histidine kinase
HW07_RS13440	COG0625	glutathione transferase activity
HW07_RS13460	COG0583	DNA-binding transcription factor activity
HW07_RS13465	COG1595	DNA-templated transcription, initiation
HW07_RS13470	COG3712	iron ion homeostasis
HW07_RS13510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW07_RS13520	COG2382	esterase
HW07_RS13540	COG0583	DNA-binding transcription factor activity
HW07_RS13565	COG1760	l-serine dehydratase
HW07_RS13570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HW07_RS13605	COG2217	Heavy metal translocating P-type atpase
HW07_RS13620	COG0583	DNA-binding transcription factor activity
HW07_RS13640	COG1566	PFAM secretion protein HlyD family protein
HW07_RS13700	COG1335	isochorismatase
HW07_RS13710	COG0583	DNA-binding transcription factor activity
HW07_RS13750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HW07_RS13755	COG1121	(ABC) transporter
HW07_RS13845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS13870	COG0735	belongs to the Fur family
HW07_RS13880	COG1304	FMN binding
HW07_RS13910	COG2197	response regulator
HW07_RS14000	COG3829	transcription factor binding
HW07_RS14025	COG3829	transcription factor binding
HW07_RS14030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW07_RS14035	COG0584	glycerophosphoryl diester phosphodiesterase
HW07_RS14040	COG2011	ABC-type metal ion transport system permease component
HW07_RS14050	COG1464	Belongs to the NlpA lipoprotein family
HW07_RS14080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW07_RS14085	COG1070	Carbohydrate kinase
HW07_RS14090	COG0246	Mannitol dehydrogenase
HW07_RS14105	COG1175	transmembrane transport
HW07_RS14125	COG4771	TonB-dependent receptor
HW07_RS14140	COG1917	Cupin 2, conserved barrel domain protein
HW07_RS14140	COG4977	sequence-specific DNA binding
HW07_RS14155	COG1116	anion transmembrane transporter activity
HW07_RS14160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HW07_RS14165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW07_RS14185	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS14200	COG3265	gluconokinase activity
HW07_RS14205	COG1609	Transcriptional regulator
HW07_RS14215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS14220	COG0583	DNA-binding transcription factor activity
HW07_RS14240	COG1396	sequence-specific DNA binding
HW07_RS14250	COG2175	clavaminate synthase activity
HW07_RS14260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HW07_RS14290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW07_RS14290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HW07_RS14300	COG3469	chitinase activity
HW07_RS14305	COG2188	Transcriptional regulator
HW07_RS14310	COG1053	succinate dehydrogenase
HW07_RS14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HW07_RS14360	COG4772	TonB-dependent receptor
HW07_RS14405	COG0431	NADPH-dependent FMN reductase
HW07_RS14410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HW07_RS14420	COG0640	Transcriptional regulator
HW07_RS14425	COG2207	Transcriptional regulator
HW07_RS14430	COG1064	alcohol dehydrogenase
HW07_RS14455	COG1309	transcriptional regulator
HW07_RS14465	COG2329	Antibiotic biosynthesis monooxygenase
HW07_RS14500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW07_RS14510	COG1609	Transcriptional regulator
HW07_RS14545	COG0252	asparaginase activity
HW07_RS14550	COG1115	amino acid carrier protein
HW07_RS14595	COG1053	succinate dehydrogenase
HW07_RS14605	COG0728	peptidoglycan biosynthetic process
HW07_RS14670	COG2258	MOSC domain
HW07_RS14705	COG2508	Transcriptional regulator
HW07_RS14715	COG4447	cellulose binding
HW07_RS14720	COG2409	Drug exporters of the RND superfamily
HW07_RS14740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS14755	COG2072	flavoprotein involved in K transport
HW07_RS14770	COG0531	amino acid
HW07_RS14775	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS14780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HW07_RS14795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW07_RS14800	COG3162	membrane
HW07_RS14805	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS14840	COG3008	intermembrane lipid transfer
HW07_RS14845	COG2995	paraquat-inducible protein a
HW07_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS14860	COG4948	Mandelate Racemase Muconate Lactonizing
HW07_RS14865	COG2271	Major facilitator Superfamily
HW07_RS14880	COG3618	amidohydrolase
HW07_RS14885	COG2271	Major facilitator Superfamily
HW07_RS14920	COG0765	amino acid transport
HW07_RS14925	COG0765	amino acid transport
HW07_RS14940	COG2084	Dehydrogenase
HW07_RS14950	COG2130	NADP-dependent
HW07_RS14955	COG1309	transcriptional regulator
HW07_RS14975	COG0366	Alpha amylase catalytic
HW07_RS14980	COG0517	IMP dehydrogenase activity
HW07_RS15000	COG1063	alcohol dehydrogenase
HW07_RS15010	COG3546	catalase activity
HW07_RS15015	COG3685	Protein conserved in bacteria
HW07_RS15045	COG2890	protein-(glutamine-N5) methyltransferase activity
HW07_RS15060	COG4191	Histidine kinase
HW07_RS15060	COG0784	Response regulator, receiver
HW07_RS15090	COG1363	Peptidase, m42
HW07_RS15135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HW07_RS15180	COG3568	Endonuclease Exonuclease Phosphatase
HW07_RS15185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW07_RS15190	COG0392	lysyltransferase activity
HW07_RS15200	COG0366	Alpha amylase catalytic
HW07_RS15220	COG1285	pathogenesis
HW07_RS15245	COG0058	SHG alpha-glucan phosphorylase activity
HW07_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS15295	COG2323	membrane
HW07_RS15315	COG3121	Chaperone
HW07_RS15325	COG3188	usher protein
HW07_RS15330	COG3121	Chaperone
HW07_RS15340	COG3969	phosphoadenosine phosphosulfate
HW07_RS15350	COG1475	DNA binding
HW07_RS15365	COG0583	DNA-binding transcription factor activity
HW07_RS15385	COG1063	alcohol dehydrogenase
HW07_RS15400	COG2169	Transcriptional regulator
HW07_RS15400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW07_RS15420	COG0583	DNA-binding transcription factor activity
HW07_RS15425	COG2814	Major facilitator Superfamily
HW07_RS15445	COG1984	allophanate hydrolase subunit 2
HW07_RS15455	COG0028	Belongs to the TPP enzyme family
HW07_RS15465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HW07_RS15470	COG1045	serine acetyltransferase
HW07_RS15475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HW07_RS15495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW07_RS15500	COG0300	oxidoreductase activity
HW07_RS15540	COG2814	Major facilitator Superfamily
HW07_RS15550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HW07_RS15570	COG0596	Alpha beta hydrolase
HW07_RS15575	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HW07_RS15580	COG0367	asparagine synthase
HW07_RS15590	COG1522	sequence-specific DNA binding
HW07_RS15610	COG1113	amino acid transport
HW07_RS15620	COG2010	Cytochrome c
HW07_RS15625	COG2010	Cytochrome c
HW07_RS15645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HW07_RS15645	COG3153	acetyltransferase
HW07_RS15650	COG5001	Diguanylate cyclase
HW07_RS15660	COG4206	TonB-dependent receptor
HW07_RS15670	COG2192	nodulation
HW07_RS15675	COG2814	Major facilitator Superfamily
HW07_RS15705	COG1104	cysteine desulfurase activity
HW07_RS15710	COG4172	Belongs to the ABC transporter superfamily
HW07_RS15715	COG4239	(ABC) transporter, permease
HW07_RS15720	COG4174	ABC transporter (Permease)
HW07_RS15730	COG4771	TonB-dependent receptor
HW07_RS15745	COG0583	DNA-binding transcription factor activity
HW07_RS15765	COG1595	DNA-templated transcription, initiation
HW07_RS15780	COG2207	Transcriptional regulator
HW07_RS15800	COG0564	pseudouridine synthase activity
HW07_RS15815	COG0531	amino acid
HW07_RS15820	COG0174	glutamine synthetase
HW07_RS15835	COG0028	Belongs to the TPP enzyme family
HW07_RS15850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW07_RS15875	COG1522	sequence-specific DNA binding
HW07_RS15915	COG1309	transcriptional regulator
HW07_RS15920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS15925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS15935	COG3204	pilus organization
HW07_RS15940	COG0789	Transcriptional regulator
HW07_RS15945	COG1960	acyl-CoA dehydrogenase activity
HW07_RS15950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HW07_RS15980	COG0179	Fumarylacetoacetate (FAA) hydrolase
HW07_RS15995	COG3290	protein histidine kinase activity
HW07_RS15995	COG3829	transcription factor binding
HW07_RS16000	COG2610	gluconate transmembrane transporter activity
HW07_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS16010	COG2031	fatty acid transporter
HW07_RS16025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HW07_RS16030	COG0583	DNA-binding transcription factor activity
HW07_RS16035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HW07_RS16040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW07_RS16060	COG2205	protein histidine kinase activity
HW07_RS16125	COG3851	Histidine kinase
HW07_RS16140	COG0784	Response regulator, receiver
HW07_RS16140	COG2205	protein histidine kinase activity
HW07_RS16160	COG2194	sulfuric ester hydrolase activity
HW07_RS16205	COG0488	(ABC) transporter
HW07_RS16220	COG0583	DNA-binding transcription factor activity
HW07_RS16225	COG1278	Cold shock
HW07_RS16275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HW07_RS16280	COG1609	Transcriptional regulator
HW07_RS16285	COG1172	Belongs to the binding-protein-dependent transport system permease family
HW07_RS16290	COG1129	ABC transporter
HW07_RS16320	COG2010	Cytochrome c
HW07_RS16325	COG0753	catalase activity
HW07_RS16390	COG1944	ATP diphosphatase activity
HW07_RS16410	COG4771	TonB-dependent receptor
HW07_RS16415	COG0275	rRNA processing
HW07_RS16420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW07_RS16420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HW07_RS16435	COG0579	oxidoreductase
HW07_RS16470	COG1595	DNA-templated transcription, initiation
HW07_RS16475	COG3712	iron ion homeostasis
HW07_RS16495	COG2814	Major facilitator Superfamily
HW07_RS16545	COG2197	response regulator
HW07_RS16570	COG2366	antibiotic biosynthetic process
HW07_RS16585	COG0625	glutathione transferase activity
HW07_RS16605	COG0417	DNA replication proofreading
HW07_RS16650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS16720	COG1309	transcriptional regulator
HW07_RS16740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HW07_RS16745	COG0583	DNA-binding transcription factor activity
HW07_RS16755	COG2354	Protein conserved in bacteria
HW07_RS16760	COG3278	Belongs to the heme-copper respiratory oxidase family
HW07_RS16770	COG2239	Acts as a magnesium transporter
HW07_RS16785	COG3706	GGDEF domain
HW07_RS16785	COG2203	Gaf domain
HW07_RS16785	COG5001	Diguanylate cyclase
HW07_RS16785	COG4251	negative regulation of phosphorylation
HW07_RS16795	COG4977	sequence-specific DNA binding
HW07_RS16800	COG3813	Protein conserved in bacteria
HW07_RS16865	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW07_RS16890	COG0604	alcohol dehydrogenase
HW07_RS16895	COG0616	signal peptide processing
HW07_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS16925	COG0583	DNA-binding transcription factor activity
HW07_RS16950	COG1024	Enoyl-CoA hydratase
HW07_RS16960	COG0531	amino acid
HW07_RS16975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HW07_RS16995	COG0741	lytic transglycosylase activity
HW07_RS16995	COG1388	LysM domain
HW07_RS17000	COG4166	transmembrane transport
HW07_RS17005	COG4166	transmembrane transport
HW07_RS17010	COG4174	ABC transporter (Permease)
HW07_RS17015	COG4239	(ABC) transporter, permease
HW07_RS17020	COG4172	Belongs to the ABC transporter superfamily
HW07_RS17030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW07_RS17045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HW07_RS17070	COG0745	RESPONSE REGULATOR receiver
HW07_RS17075	COG2205	protein histidine kinase activity
HW07_RS17080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HW07_RS17125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HW07_RS17145	COG0589	response to stress
HW07_RS17170	COG2201	protein-glutamate methylesterase activity
HW07_RS17180	COG2223	nitrite transmembrane transporter activity
HW07_RS17185	COG0515	serine threonine protein kinase
HW07_RS17190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HW07_RS17195	COG2146	nitrite reductase [NAD(P)H] activity
HW07_RS17200	COG0243	molybdopterin cofactor binding
HW07_RS17220	COG0668	transmembrane transport
HW07_RS17260	COG0189	ligase activity
HW07_RS17260	COG4067	protein conserved in archaea
HW07_RS17305	COG2909	trisaccharide binding
HW07_RS17310	COG2909	trisaccharide binding
HW07_RS17345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HW07_RS17400	COG0519	Catalyzes the synthesis of GMP from XMP
HW07_RS17415	COG0667	Aldo Keto reductase
HW07_RS17430	COG0183	Belongs to the thiolase family
HW07_RS17450	COG1305	Transglutaminase-like
HW07_RS17460	COG2308	Evidence 4 Homologs of previously reported genes of
HW07_RS17465	COG0505	Belongs to the CarA family
HW07_RS17485	COG1317	bacterial-type flagellum organization
HW07_RS17595	COG4789	Type iii secretion
HW07_RS17645	COG4790	Type iii secretion
HW07_RS17650	COG4794	Type iii secretion
HW07_RS17655	COG4791	protein targeting
HW07_RS17660	COG4792	protein secretion
HW07_RS17740	COG2840	Smr protein MutS2
HW07_RS17760	COG2815	serine threonine protein kinase
HW07_RS17760	COG0515	serine threonine protein kinase
HW07_RS17800	COG2204	response regulator
HW07_RS17845	COG0625	glutathione transferase activity
HW07_RS17850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HW07_RS17865	COG3135	benzoate transporter
HW07_RS17880	COG2130	NADP-dependent
HW07_RS17895	COG0840	transmembrane signaling receptor activity
HW07_RS17905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HW07_RS17945	COG0745	RESPONSE REGULATOR receiver
HW07_RS17950	COG2205	protein histidine kinase activity
HW07_RS17975	COG1960	acyl-CoA dehydrogenase activity
HW07_RS17985	COG1024	Enoyl-CoA hydratase
HW07_RS17990	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW07_RS17995	COG2186	Transcriptional regulator
HW07_RS18000	COG2807	transmembrane transport
HW07_RS18005	COG0628	permease
HW07_RS18015	COG0625	glutathione transferase activity
HW07_RS18045	COG1022	Amp-dependent synthetase and ligase
HW07_RS18075	COG0784	Response regulator, receiver
HW07_RS18075	COG2205	protein histidine kinase activity
HW07_RS18075	COG5002	protein histidine kinase activity
HW07_RS18115	COG1846	Transcriptional regulator
HW07_RS18120	COG2080	2 iron, 2 sulfur cluster binding
HW07_RS18125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HW07_RS18125	COG2010	Cytochrome c
HW07_RS18130	COG2010	Cytochrome c
HW07_RS18130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HW07_RS18135	COG2207	Transcriptional regulator
HW07_RS18210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HW07_RS18215	COG1053	succinate dehydrogenase
HW07_RS18220	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HW07_RS18225	COG2009	succinate dehydrogenase
HW07_RS18255	COG2084	Dehydrogenase
HW07_RS18270	COG3738	Protein conserved in bacteria
HW07_RS18300	COG0251	oxidation-reduction process
HW07_RS18305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS18315	COG0174	glutamine synthetase
HW07_RS18320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS18340	COG0840	transmembrane signaling receptor activity
HW07_RS18355	COG3278	Belongs to the heme-copper respiratory oxidase family
HW07_RS18370	COG2010	Cytochrome c
HW07_RS18375	COG3278	Belongs to the heme-copper respiratory oxidase family
HW07_RS18390	COG2010	Cytochrome c
HW07_RS18400	COG0348	domain, Protein
HW07_RS18410	COG2217	Heavy metal translocating P-type atpase
HW07_RS18450	COG2076	Multidrug Resistance protein
HW07_RS18480	COG1960	acyl-CoA dehydrogenase activity
HW07_RS18495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HW07_RS18525	COG1196	nuclear chromosome segregation
HW07_RS18555	COG0402	S-adenosylhomocysteine deaminase activity
HW07_RS18570	COG2252	PERMEase
HW07_RS18630	COG2233	PERMEase
HW07_RS18645	COG1309	transcriptional regulator
HW07_RS18655	COG3960	tartronate-semialdehyde synthase activity
HW07_RS18660	COG3622	Belongs to the hyi family
HW07_RS18665	COG2084	Dehydrogenase
HW07_RS18675	COG0469	pyruvate kinase activity
HW07_RS18680	COG4413	Urea transporter
HW07_RS18685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HW07_RS18700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HW07_RS18710	COG3192	ethanolamine utilization protein
HW07_RS18725	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW07_RS18730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HW07_RS18805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HW07_RS18820	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS18825	COG1496	oxidoreductase activity
HW07_RS18850	COG0835	chemotaxis
HW07_RS18860	COG1192	Involved in chromosome partitioning
HW07_RS18865	COG1360	Flagellar Motor Protein
HW07_RS18870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HW07_RS18880	COG0643	Histidine kinase
HW07_RS18880	COG0784	Response regulator, receiver
HW07_RS18880	COG2198	Histidine kinase
HW07_RS18910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HW07_RS18915	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HW07_RS18935	COG1987	bacterial-type flagellum assembly
HW07_RS18975	COG2832	Protein of unknown function (DUF454)
HW07_RS18990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS18995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS19005	COG5001	Diguanylate cyclase
HW07_RS19005	COG3300	MHYT domain
HW07_RS19040	COG0488	(ABC) transporter
HW07_RS19095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW07_RS19105	COG0583	DNA-binding transcription factor activity
HW07_RS19120	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HW07_RS19135	COG3264	Mechanosensitive ion channel
HW07_RS19135	COG1196	nuclear chromosome segregation
HW07_RS19140	COG0116	Belongs to the methyltransferase superfamily
HW07_RS19140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HW07_RS19150	COG0210	DNA helicase
HW07_RS19175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HW07_RS19235	COG2207	Transcriptional regulator
HW07_RS19240	COG4221	oxidoreductase activity
HW07_RS19250	COG1247	-acetyltransferase
HW07_RS19270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HW07_RS19280	COG0384	phenazine biosynthesis protein PhzF
HW07_RS19310	COG5006	permease, DMT superfamily
HW07_RS19325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HW07_RS19340	COG3795	YCII-related domain
HW07_RS19350	COG2814	Major facilitator Superfamily
HW07_RS19355	COG4941	Belongs to the sigma-70 factor family
HW07_RS19365	COG3795	YCII-related domain
HW07_RS19375	COG2197	response regulator
HW07_RS19380	COG1982	Orn Lys Arg decarboxylase major
HW07_RS19385	COG0189	ligase activity
HW07_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS19405	COG0765	amino acid transport
HW07_RS19410	COG0765	amino acid transport
HW07_RS19415	COG1126	abc transporter atp-binding protein
HW07_RS19445	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS19465	COG1253	flavin adenine dinucleotide binding
HW07_RS19470	COG0300	oxidoreductase activity
HW07_RS19480	COG0583	DNA-binding transcription factor activity
HW07_RS19490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HW07_RS19495	COG4319	ketosteroid isomerase
HW07_RS19510	COG4774	siderophore transport
HW07_RS19560	COG2814	Major facilitator Superfamily
HW07_RS19580	COG0583	DNA-binding transcription factor activity
HW07_RS19590	COG0121	glutamine amidotransferase
HW07_RS19620	COG3712	iron ion homeostasis
HW07_RS19625	COG1595	DNA-templated transcription, initiation
HW07_RS19640	COG1230	cation diffusion facilitator family transporter
HW07_RS19645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HW07_RS19705	COG1960	acyl-CoA dehydrogenase activity
HW07_RS19725	COG0406	alpha-ribazole phosphatase activity
HW07_RS19755	COG0778	Nitroreductase
HW07_RS19770	COG4206	TonB-dependent receptor
HW07_RS19780	COG1802	Transcriptional regulator
HW07_RS19790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS19825	COG0477	Major facilitator Superfamily
HW07_RS19845	COG0765	amino acid transport
HW07_RS19855	COG1126	abc transporter atp-binding protein
HW07_RS19865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HW07_RS19870	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS19930	COG0784	Response regulator, receiver
HW07_RS19930	COG4191	Histidine kinase
HW07_RS19985	COG1289	transmembrane transporter activity
HW07_RS20000	COG2207	Transcriptional regulator
HW07_RS20020	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW07_RS20025	COG2957	Belongs to the agmatine deiminase family
HW07_RS20040	COG2957	Belongs to the agmatine deiminase family
HW07_RS20045	COG0583	DNA-binding transcription factor activity
HW07_RS20055	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HW07_RS20080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HW07_RS20090	COG0318	PFAM AMP-dependent synthetase and ligase
HW07_RS20095	COG0367	asparagine synthase
HW07_RS20105	COG2211	Major facilitator Superfamily
HW07_RS20155	COG1335	isochorismatase
HW07_RS20160	COG0583	DNA-binding transcription factor activity
HW07_RS20170	COG0791	NLP P60 protein
HW07_RS20175	COG0791	NLP P60 protein
HW07_RS20185	COG3829	transcription factor binding
HW07_RS20200	COG2818	Glycosylase
HW07_RS20225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HW07_RS20230	COG1960	acyl-CoA dehydrogenase activity
HW07_RS20240	COG0625	glutathione transferase activity
HW07_RS20265	COG3447	MASE1 domain protein
HW07_RS20265	COG5001	Diguanylate cyclase
HW07_RS20265	COG5002	protein histidine kinase activity
HW07_RS20285	COG4459	periplasmic nitrate reductase
HW07_RS20290	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW07_RS20290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HW07_RS20295	COG3062	negative regulation of establishment of protein localization
HW07_RS20305	COG3043	anaerobic respiration
HW07_RS20310	COG3005	denitrification pathway
HW07_RS20315	COG2951	lytic endotransglycosylase activity
HW07_RS20320	COG0861	Integral membrane protein TerC family
HW07_RS20325	COG0753	catalase activity
HW07_RS20345	COG2977	Belongs to the P-Pant transferase superfamily
HW07_RS20350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HW07_RS20365	COG2226	methyltransferase
HW07_RS20380	COG2205	protein histidine kinase activity
HW07_RS20385	COG0745	RESPONSE REGULATOR receiver
HW07_RS20390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HW07_RS20390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW07_RS20395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HW07_RS20400	COG1943	Transposase
HW07_RS20435	COG0531	amino acid
HW07_RS20465	COG0583	DNA-binding transcription factor activity
HW07_RS20470	COG3257	ureidoglycine aminohydrolase activity
HW07_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS20485	COG0604	alcohol dehydrogenase
HW07_RS20485	COG3321	synthase
HW07_RS20490	COG2197	response regulator
HW07_RS20530	COG0583	DNA-binding transcription factor activity
HW07_RS20535	COG0667	Aldo Keto reductase
HW07_RS20565	COG0242	peptide deformylase activity
HW07_RS20575	COG2199	diguanylate cyclase activity
HW07_RS20580	COG2885	chlorophyll binding
HW07_RS20610	COG1132	(ABC) transporter
HW07_RS20625	COG4628	conserved protein (DUF2132)
HW07_RS20630	COG2133	pyrroloquinoline quinone binding
HW07_RS20645	COG2207	Transcriptional regulator
HW07_RS20650	COG0477	Major facilitator Superfamily
HW07_RS20665	COG2882	bacterial-type flagellum organization
HW07_RS20725	COG1334	flagellar protein FlaG
HW07_RS20785	COG4787	bacterial-type flagellum-dependent cell motility
HW07_RS20795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HW07_RS20805	COG1815	bacterial-type flagellum-dependent cell motility
HW07_RS20855	COG0326	Molecular chaperone. Has ATPase activity
HW07_RS20870	COG3189	MarR family transcriptional regulator
HW07_RS20890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HW07_RS20905	COG2212	antiporter activity
HW07_RS20910	COG1863	multisubunit Na H antiporter MnhE subunit
HW07_RS20915	COG0651	ATP synthesis coupled electron transport
HW07_RS20920	COG1006	Multisubunit Na H antiporter MnhC subunit
HW07_RS20925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HW07_RS20925	COG2111	Na H antiporter
HW07_RS20930	COG3133	Outer membrane lipoprotein
HW07_RS20940	COG1929	Belongs to the glycerate kinase type-1 family
HW07_RS20945	COG2610	gluconate transmembrane transporter activity
HW07_RS20950	COG3835	regulator
HW07_RS20960	COG2885	chlorophyll binding
HW07_RS20975	COG1199	ATP-dependent helicase activity
HW07_RS21015	COG2860	membrane
HW07_RS21030	COG0653	protein targeting
HW07_RS21035	COG0625	glutathione transferase activity
HW07_RS21060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS21065	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS21090	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS21095	COG1960	acyl-CoA dehydrogenase activity
HW07_RS21100	COG1024	Enoyl-CoA hydratase
HW07_RS21105	COG1960	acyl-CoA dehydrogenase activity
HW07_RS21115	COG2814	Major facilitator Superfamily
HW07_RS21120	COG2030	dehydratase
HW07_RS21160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HW07_RS21165	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HW07_RS21180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HW07_RS21190	COG0425	Belongs to the sulfur carrier protein TusA family
HW07_RS21245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HW07_RS21250	COG3188	usher protein
HW07_RS21270	COG1051	belongs to the nudix hydrolase family
HW07_RS21295	COG0602	queuosine metabolic process
HW07_RS21300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HW07_RS21330	COG0824	Thioesterase
HW07_RS21360	COG0783	Belongs to the Dps family
HW07_RS21405	COG3118	belongs to the thioredoxin family
HW07_RS21440	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HW07_RS21460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HW07_RS21500	COG3122	Protein conserved in bacteria
HW07_RS21510	COG3956	TIGRFAM MazG family protein
HW07_RS21515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW07_RS21545	COG0784	Response regulator, receiver
HW07_RS21545	COG2205	protein histidine kinase activity
HW07_RS21545	COG5002	protein histidine kinase activity
HW07_RS21550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HW07_RS21600	COG3038	cytochrome b561
HW07_RS21620	COG4807	Protein conserved in bacteria
HW07_RS21630	COG2239	Acts as a magnesium transporter
HW07_RS21700	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HW07_RS21795	COG2301	Belongs to the HpcH HpaI aldolase family
HW07_RS21805	COG2079	MmgE PrpD family protein
HW07_RS21815	COG1960	acyl-CoA dehydrogenase activity
HW07_RS21820	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HW07_RS21825	COG0583	DNA-binding transcription factor activity
HW07_RS21830	COG0583	DNA-binding transcription factor activity
HW07_RS21890	COG1113	amino acid transport
HW07_RS21910	COG0604	alcohol dehydrogenase
HW07_RS21910	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS21910	COG3321	synthase
HW07_RS21920	COG5001	Diguanylate cyclase
HW07_RS21920	COG5002	protein histidine kinase activity
HW07_RS21940	COG0271	Belongs to the BolA IbaG family
HW07_RS21980	COG0492	ferredoxin-NADP+ reductase activity
HW07_RS21985	COG0450	alkyl hydroperoxide reductase
HW07_RS22020	COG1307	EDD domain protein, DegV family
HW07_RS22030	COG1309	transcriptional regulator
HW07_RS22035	COG0386	Belongs to the glutathione peroxidase family
HW07_RS22060	COG0204	Acyl-transferase
HW07_RS22065	COG2885	chlorophyll binding
HW07_RS22070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HW07_RS22085	COG2267	carboxylic ester hydrolase activity
HW07_RS22135	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HW07_RS22170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HW07_RS22185	COG0546	phosphoglycolate phosphatase activity
HW07_RS22200	COG3023	N-Acetylmuramoyl-L-alanine amidase
HW07_RS22215	COG0656	L-ascorbic acid biosynthetic process
HW07_RS22240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HW07_RS22250	COG1802	Transcriptional regulator
HW07_RS22260	COG0372	Belongs to the citrate synthase family
HW07_RS22275	COG2079	MmgE PrpD family protein
HW07_RS22290	COG1113	amino acid transport
HW07_RS22320	COG0583	DNA-binding transcription factor activity
HW07_RS22325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HW07_RS22335	COG4206	TonB-dependent receptor
HW07_RS22345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HW07_RS22410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HW07_RS22490	COG3180	Ammonia monooxygenase
HW07_RS22500	COG2720	vancomycin resistance protein
HW07_RS22515	COG1960	acyl-CoA dehydrogenase activity
HW07_RS22520	COG1024	Enoyl-CoA hydratase
HW07_RS22540	COG2910	NAD(P)H-binding
HW07_RS22545	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HW07_RS22645	COG0583	DNA-binding transcription factor activity
HW07_RS22660	COG0463	Glycosyl transferase, family 2
HW07_RS22670	COG0154	amidase activity
HW07_RS22690	COG0583	DNA-binding transcription factor activity
HW07_RS22700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HW07_RS22735	COG2831	hemolysin activation secretion protein
HW07_RS22885	COG0420	3'-5' exonuclease activity
HW07_RS22895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HW07_RS22900	COG1074	ATP-dependent DNA helicase activity
HW07_RS22905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HW07_RS22910	COG0095	Lipoate-protein ligase
HW07_RS22915	COG0697	spore germination
HW07_RS22930	COG0840	transmembrane signaling receptor activity
HW07_RS22940	COG0306	phosphate transporter
HW07_RS23000	COG4964	Belongs to the GSP D family
HW07_RS23020	COG0433	COG0433 Predicted ATPase
HW07_RS23060	COG0788	formyltetrahydrofolate deformylase activity
HW07_RS23070	COG2925	Exonuclease
HW07_RS23100	COG0714	Associated with various cellular activities
HW07_RS23130	COG0589	response to stress
HW07_RS23140	COG1024	Enoyl-CoA hydratase
HW07_RS23150	COG3706	GGDEF domain
HW07_RS23170	COG0693	protein deglycase activity
HW07_RS23185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW07_RS23200	COG0154	amidase activity
HW07_RS23210	COG1473	amidohydrolase
HW07_RS23225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HW07_RS23230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HW07_RS23230	COG0426	domain, Protein
HW07_RS23250	COG0589	response to stress
HW07_RS23265	COG2814	Major facilitator Superfamily
HW07_RS23270	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS23285	COG1918	ferrous iron import across plasma membrane
HW07_RS23300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HW07_RS23340	COG1704	LemA family
HW07_RS23365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS23370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS23385	COG3642	lipopolysaccharide core region biosynthetic process
HW07_RS23395	COG2205	protein histidine kinase activity
HW07_RS23400	COG0745	RESPONSE REGULATOR receiver
HW07_RS23435	COG3030	protein affecting phage T7 exclusion by the F plasmid
HW07_RS23445	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS23470	COG0668	transmembrane transport
HW07_RS23480	COG0745	RESPONSE REGULATOR receiver
HW07_RS23495	COG2096	Adenosyltransferase
HW07_RS23500	COG0494	nUDIX hydrolase
HW07_RS23525	COG1196	nuclear chromosome segregation
HW07_RS23525	COG0739	heme binding
HW07_RS23525	COG0741	lytic transglycosylase activity
HW07_RS23570	COG0772	Belongs to the SEDS family
HW07_RS23585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HW07_RS23625	COG3107	peptidoglycan biosynthetic process
HW07_RS23640	COG2823	Periplasmic or secreted lipoprotein
HW07_RS23645	COG2969	positive regulation of protein catabolic process
HW07_RS23650	COG0625	glutathione transferase activity
HW07_RS23655	COG2857	Cytochrome c1
HW07_RS23660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HW07_RS23665	COG0723	plastoquinol--plastocyanin reductase activity
HW07_RS23680	COG0667	Aldo Keto reductase
HW07_RS23685	COG1960	acyl-CoA dehydrogenase activity
HW07_RS23700	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW07_RS23710	COG2945	thiolester hydrolase activity
HW07_RS23730	COG2951	lytic endotransglycosylase activity
HW07_RS23740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HW07_RS23780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HW07_RS23785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HW07_RS23790	COG1127	ABC transporter
HW07_RS23800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HW07_RS23815	COG1137	ATPase activity
HW07_RS23870	COG0312	modulator of DNA gyrase
HW07_RS23880	COG0312	modulator of DNA gyrase
HW07_RS23885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HW07_RS23895	COG1530	ribonuclease E activity
HW07_RS23910	COG1792	Involved in formation and maintenance of cell shape
HW07_RS23915	COG1077	Cell shape determining protein MreB Mrl
HW07_RS23935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HW07_RS23940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HW07_RS23945	COG4676	Protein conserved in bacteria
HW07_RS23950	COG5445	Predicted secreted protein (DUF2300)
HW07_RS23965	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HW07_RS23970	COG4676	Protein conserved in bacteria
HW07_RS23975	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HW07_RS23990	COG0747	negative chemotaxis
HW07_RS23995	COG0747	negative chemotaxis
HW07_RS24010	COG0747	negative chemotaxis
HW07_RS24025	COG0747	negative chemotaxis
HW07_RS24030	COG0601	transmembrane transport
HW07_RS24035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HW07_RS24040	COG0444	Belongs to the ABC transporter superfamily
HW07_RS24045	COG4608	Belongs to the ABC transporter superfamily
HW07_RS24060	COG1984	allophanate hydrolase subunit 2
HW07_RS24080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HW07_RS24085	COG4774	siderophore transport
HW07_RS24100	COG2194	sulfuric ester hydrolase activity
HW07_RS24110	COG0019	diaminopimelate decarboxylase activity
HW07_RS24150	COG4969	Belongs to the N-Me-Phe pilin family
HW07_RS24215	COG1252	NADH dehydrogenase
HW07_RS24220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HW07_RS24295	COG4969	Belongs to the N-Me-Phe pilin family
HW07_RS24335	COG1047	Peptidyl-prolyl cis-trans
HW07_RS24350	COG0196	riboflavin kinase activity
HW07_RS24365	COG3045	CreA protein
HW07_RS24390	COG0142	geranyltranstransferase activity
HW07_RS24405	COG0545	Peptidyl-prolyl cis-trans isomerase
HW07_RS24425	COG1067	ATP-dependent peptidase activity
HW07_RS24450	COG4650	regulator
HW07_RS24465	COG1690	Belongs to the RtcB family
HW07_RS24470	COG3541	Predicted nucleotidyltransferase
HW07_RS24490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HW07_RS24515	COG1136	(ABC) transporter
HW07_RS24515	COG0577	efflux transmembrane transporter activity
HW07_RS24520	COG1136	(ABC) transporter
HW07_RS24520	COG0577	efflux transmembrane transporter activity
HW07_RS24525	COG0488	(ABC) transporter
HW07_RS24545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HW07_RS24550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS24575	COG0523	cobalamin synthesis protein
HW07_RS24580	COG2879	small protein
HW07_RS24585	COG1966	Carbon starvation protein
HW07_RS24655	COG3608	succinylglutamate desuccinylase aspartoacylase
HW07_RS24655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HW07_RS24660	COG2010	Cytochrome c
HW07_RS24700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HW07_RS24710	COG0833	amino acid
HW07_RS24715	COG2119	membrane
HW07_RS24730	COG0501	Belongs to the peptidase M48B family
HW07_RS24735	COG0840	transmembrane signaling receptor activity
HW07_RS24740	COG2135	peptidase activity
HW07_RS24745	COG1285	pathogenesis
HW07_RS24805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HW07_RS24860	COG1090	epimerase
HW07_RS24865	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HW07_RS24875	COG0789	Transcriptional regulator
HW07_RS24895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HW07_RS24950	COG0012	GTP binding
HW07_RS24965	COG4974	Belongs to the 'phage' integrase family
HW07_RS24975	COG4128	Pfam Zonular occludens toxin
HW07_RS25045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HW07_RS25060	COG3549	Plasmid maintenance system killer
HW07_RS25075	COG0288	reversible hydration of carbon dioxide
HW07_RS25085	COG0456	acetyltransferase
HW07_RS25130	COG1840	ABC-type Fe3 transport system, periplasmic component
HW07_RS25135	COG1178	ABC-type Fe3 transport system permease component
HW07_RS25140	COG3008	intermembrane lipid transfer
HW07_RS25145	COG2995	paraquat-inducible protein a
HW07_RS25150	COG2995	paraquat-inducible protein a
HW07_RS25190	COG1183	phosphatidylcholine synthase activity
HW07_RS25205	COG0028	Belongs to the TPP enzyme family
HW07_RS25215	COG3098	single-species biofilm formation
HW07_RS25225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HW07_RS25260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HW07_RS25265	COG4558	Periplasmic binding protein
HW07_RS25270	COG3720	iron ion transport
HW07_RS25275	COG4771	TonB-dependent receptor
HW07_RS25300	COG0436	Aminotransferase
HW07_RS25310	COG2321	neutral zinc metallopeptidase
HW07_RS25320	COG2252	PERMEase
HW07_RS25335	COG0436	Aminotransferase
HW07_RS25340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW07_RS25355	COG4191	Histidine kinase
HW07_RS25460	COG0195	Participates in both transcription termination and antitermination
HW07_RS25495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HW07_RS25565	COG0497	DNA recombination
HW07_RS25595	COG2186	Transcriptional regulator
HW07_RS25600	COG1620	l-lactate permease
HW07_RS25650	COG0697	spore germination
HW07_RS25670	COG0697	spore germination
HW07_RS25675	COG1522	sequence-specific DNA binding
HW07_RS25685	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS25705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW07_RS25735	COG0509	glycine decarboxylation via glycine cleavage system
HW07_RS25790	COG3276	selenocysteine insertion sequence binding
HW07_RS25805	COG2864	formate dehydrogenase
HW07_RS25810	COG0437	4 iron, 4 sulfur cluster binding
HW07_RS25820	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HW07_RS25825	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS25825	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW07_RS25850	COG0463	Glycosyl transferase, family 2
HW07_RS25860	COG0534	Mate efflux family protein
HW07_RS25870	COG1283	sodium-dependent phosphate transmembrane transporter activity
HW07_RS25895	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HW07_RS25920	COG4221	oxidoreductase activity
HW07_RS25925	COG1272	protein, Hemolysin III
HW07_RS25960	COG0023	Translation Initiation Factor
HW07_RS26050	COG2095	MarC family integral membrane protein
HW07_RS26055	COG0683	leucine binding
HW07_RS26070	COG0411	ABC transporter
HW07_RS26115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HW07_RS26130	COG0443	Heat shock 70 kDa protein
HW07_RS26155	COG0789	Transcriptional regulator
HW07_RS26160	COG2982	Protein involved in outer membrane biogenesis
HW07_RS26165	COG2193	ferroxidase activity
HW07_RS26175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HW07_RS26180	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HW07_RS26240	COG3712	iron ion homeostasis
HW07_RS26245	COG1595	DNA-templated transcription, initiation
HW07_RS26265	COG2814	Major facilitator Superfamily
HW07_RS26275	COG0583	DNA-binding transcription factor activity
HW07_RS26300	COG4221	oxidoreductase activity
HW07_RS26305	COG2423	ornithine cyclodeaminase activity
HW07_RS26335	COG0583	DNA-binding transcription factor activity
HW07_RS26350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HW07_RS26390	COG0668	transmembrane transport
HW07_RS26410	COG5001	Diguanylate cyclase
HW07_RS26410	COG3300	MHYT domain
HW07_RS26420	COG0305	Participates in initiation and elongation during chromosome replication
HW07_RS26450	COG0557	exoribonuclease II activity
HW07_RS26480	COG0330	HflC and HflK could
HW07_RS26485	COG0330	HflC and HflK could
HW07_RS26490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HW07_RS26510	COG0860	N-Acetylmuramoyl-L-alanine amidase
HW07_RS26515	COG0802	atpase or kinase
HW07_RS26520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HW07_RS26520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HW07_RS26575	COG3300	MHYT domain
HW07_RS26575	COG5001	Diguanylate cyclase
HW07_RS26580	COG3830	Belongs to the UPF0237 family
HW07_RS26580	COG0560	Phosphoserine phosphatase
HW07_RS26590	COG1988	membrane-bound metal-dependent
HW07_RS26605	COG3577	Aspartyl protease
HW07_RS26620	COG3150	esterase
HW07_RS26625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HW07_RS26635	COG0494	nUDIX hydrolase
HW07_RS26650	COG1538	Outer membrane efflux protein
HW07_RS26655	COG2249	NAD(P)H dehydrogenase (quinone) activity
HW07_RS26670	COG0045	succinate-CoA ligase (ADP-forming) activity
HW07_RS26675	COG1960	acyl-CoA dehydrogenase activity
HW07_RS26680	COG1024	Enoyl-CoA hydratase
HW07_RS26685	COG0833	amino acid
HW07_RS26715	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS26715	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW07_RS26725	COG1519	Transferase
HW07_RS26730	COG0583	DNA-binding transcription factor activity
HW07_RS26745	COG0667	Aldo Keto reductase
HW07_RS26755	COG1960	acyl-CoA dehydrogenase activity
HW07_RS26760	COG1960	acyl-CoA dehydrogenase activity
HW07_RS26785	COG1215	transferase activity, transferring glycosyl groups
HW07_RS26805	COG0438	transferase activity, transferring glycosyl groups
HW07_RS26810	COG2192	nodulation
HW07_RS26835	COG0438	transferase activity, transferring glycosyl groups
HW07_RS26840	COG0859	PFAM glycosyl transferase family 9
HW07_RS26845	COG0859	PFAM glycosyl transferase family 9
HW07_RS26890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HW07_RS26895	COG1960	acyl-CoA dehydrogenase activity
HW07_RS26910	COG1196	nuclear chromosome segregation
HW07_RS26910	COG3264	Mechanosensitive ion channel
HW07_RS26920	COG0730	response to heat
HW07_RS26925	COG2873	o-acetylhomoserine
HW07_RS26940	COG1192	Involved in chromosome partitioning
HW07_RS26945	COG0583	DNA-binding transcription factor activity
HW07_RS26950	COG2814	Major facilitator Superfamily
HW07_RS26975	COG0493	'glutamate synthase
HW07_RS26980	COG0069	glutamate synthase activity
HW07_RS26980	COG0067	glutamate synthase
HW07_RS26980	COG0070	glutamate synthase
HW07_RS27030	COG0281	malic enzyme
HW07_RS27050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HW07_RS27165	COG0840	transmembrane signaling receptor activity
HW07_RS27175	COG1126	abc transporter atp-binding protein
HW07_RS27180	COG0765	amino acid transport
HW07_RS27210	COG1051	belongs to the nudix hydrolase family
HW07_RS27215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HW07_RS27220	COG0251	oxidation-reduction process
HW07_RS27245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW07_RS27265	COG2986	histidine ammonia-lyase
HW07_RS27270	COG4175	Glycine betaine
HW07_RS27275	COG4176	ABC-type proline glycine betaine transport system permease component
HW07_RS27295	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HW07_RS27330	COG0402	S-adenosylhomocysteine deaminase activity
HW07_RS27380	COG0789	Transcriptional regulator
HW07_RS27385	COG1217	gtp-binding protein TYPA
HW07_RS27410	COG0668	transmembrane transport
HW07_RS27425	COG3852	Histidine kinase
HW07_RS27440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HW07_RS27470	COG4942	peptidase
HW07_RS27475	COG0793	Belongs to the peptidase S41A family
HW07_RS27480	COG2861	carbohydrate metabolic process
HW07_RS27540	COG0579	oxidoreductase
HW07_RS27550	COG1194	a g-specific adenine glycosylase
HW07_RS27560	COG0673	inositol 2-dehydrogenase activity
HW07_RS27570	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS27605	COG1846	Transcriptional regulator
HW07_RS27615	COG1566	PFAM secretion protein HlyD family protein
HW07_RS27620	COG2814	Major facilitator Superfamily
HW07_RS27630	COG0582	viral genome integration into host DNA
HW07_RS27680	COG1088	dTDP-glucose 4,6-dehydratase activity
HW07_RS27685	COG1091	dTDP-4-dehydrorhamnose reductase activity
HW07_RS27760	COG1218	3'(2'),5'-bisphosphate nucleotidase
HW07_RS27765	COG0494	nUDIX hydrolase
HW07_RS27770	COG1011	Hydrolase
HW07_RS27775	COG1652	LysM domain
HW07_RS27785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HW07_RS27805	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HW07_RS27815	COG0824	Thioesterase
HW07_RS27820	COG1454	alcohol dehydrogenase
HW07_RS27825	COG1960	acyl-CoA dehydrogenase activity
HW07_RS27830	COG1250	3-hydroxyacyl-CoA dehydrogenase
HW07_RS27830	COG1024	Enoyl-CoA hydratase
HW07_RS27840	COG0778	Nitroreductase
HW07_RS27870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HW07_RS27875	COG4067	protein conserved in archaea
HW07_RS27875	COG0189	ligase activity
HW07_RS27900	COG2183	response to ionizing radiation
HW07_RS27930	COG0306	phosphate transporter
HW07_RS27935	COG1392	Phosphate transport regulator
HW07_RS27940	COG3025	triphosphatase activity
HW07_RS27945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HW07_RS27975	COG1178	ABC-type Fe3 transport system permease component
HW07_RS27985	COG0583	DNA-binding transcription factor activity
HW07_RS28000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW07_RS28010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HW07_RS28015	COG0006	proline dipeptidase activity
HW07_RS28040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HW07_RS28050	COG0842	Transport permease protein
HW07_RS28055	COG1129	ABC transporter
HW07_RS28055	COG0842	Transport permease protein
HW07_RS28060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HW07_RS28075	COG2271	Major facilitator Superfamily
HW07_RS28090	COG2755	lipolytic protein G-D-S-L family
HW07_RS28090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HW07_RS28105	COG0248	Ppx GppA phosphatase
HW07_RS28120	COG0586	Pfam SNARE associated Golgi protein
HW07_RS28125	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HW07_RS28130	COG2050	protein possibly involved in aromatic compounds catabolism
HW07_RS28140	COG0672	)-iron permease
HW07_RS28145	COG1280	lysine exporter protein (LysE YggA)
HW07_RS28150	COG0861	Integral membrane protein TerC family
HW07_RS28160	COG0488	(ABC) transporter
HW07_RS28215	COG3275	phosphorelay sensor kinase activity
HW07_RS28245	COG0598	Magnesium transport protein CorA
HW07_RS28275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HW07_RS28345	COG0432	Pfam Uncharacterised protein family UPF0047
HW07_RS28350	COG0004	ammonium transporteR
HW07_RS28355	COG0347	Belongs to the P(II) protein family
HW07_RS28365	COG0606	chelatase, subunit chli
HW07_RS28370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW07_RS28380	COG0583	DNA-binding transcription factor activity
HW07_RS28395	COG0210	DNA helicase
HW07_RS28400	COG0028	Belongs to the TPP enzyme family
HW07_RS28410	COG0427	acetyl-CoA hydrolase
HW07_RS28420	COG1917	Cupin 2, conserved barrel domain protein
HW07_RS28420	COG1396	sequence-specific DNA binding
HW07_RS28430	COG0251	oxidation-reduction process
HW07_RS28460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HW07_RS28465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HW07_RS28470	COG2814	Major facilitator Superfamily
HW07_RS28475	COG1012	belongs to the aldehyde dehydrogenase family
HW07_RS28480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HW07_RS28500	COG0747	negative chemotaxis
HW07_RS28515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HW07_RS28555	COG3245	cytochrome
HW07_RS28575	COG0708	Exodeoxyribonuclease III
HW07_RS28590	COG1561	YicC-like family, N-terminal region
HW07_RS28605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HW07_RS28635	COG0583	DNA-binding transcription factor activity
HW07_RS28640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HW07_RS28680	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HW07_RS28685	COG0247	lactate metabolic process
HW07_RS28690	COG0277	FAD linked oxidase domain protein
HW07_RS28695	COG0277	FAD linked oxidase domain protein
HW07_RS28700	COG2186	Transcriptional regulator
HW07_RS28730	COG1253	flavin adenine dinucleotide binding
HW07_RS28735	COG0739	heme binding
HW07_RS28755	COG0573	inorganic phosphate transmembrane transporter activity
HW07_RS28795	COG0477	Major facilitator Superfamily
HW07_RS28800	COG1607	acyl-coa hydrolase
HW07_RS28825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HW07_RS28830	COG4175	Glycine betaine
HW07_RS28835	COG4176	ABC-type proline glycine betaine transport system permease component
HW07_RS28845	COG1760	l-serine dehydratase
HW07_RS28860	COG0583	DNA-binding transcription factor activity
HW07_RS28870	COG0657	acetylesterase activity
HW07_RS28885	COG3246	L-lysine catabolic process to acetate
HW07_RS28940	COG0446	pyridine nucleotide-disulphide oxidoreductase
HW07_RS28940	COG1902	pentaerythritol trinitrate reductase activity
HW07_RS28945	COG0247	lactate metabolic process
HW07_RS28945	COG2181	nitrate reductase activity
HW07_RS28965	COG3655	Transcriptional regulator
HW07_RS29005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HW07_RS29005	COG1017	nitric oxide dioxygenase activity
HW07_RS29095	COG0583	DNA-binding transcription factor activity
HW07_RS29110	COG2391	methyltransferase activity
HW07_RS29135	COG0511	ligase activity, forming carbon-carbon bonds
HW07_RS29135	COG5016	pyruvate
HW07_RS29140	COG0439	Biotin carboxylase
HW07_RS29145	COG0583	DNA-binding transcription factor activity
HW07_RS29160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HW07_RS29165	COG0826	peptidase U32
HW07_RS29185	COG0210	DNA helicase
HW07_RS29195	COG0427	acetyl-CoA hydrolase
HW07_RS29210	COG0438	transferase activity, transferring glycosyl groups
HW07_RS29255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HW07_RS29260	COG2755	lipolytic protein G-D-S-L family
HW07_RS29260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HW07_RS29300	COG0679	Auxin Efflux Carrier
HW07_RS29310	COG2851	Citrate transporter
HW07_RS29315	COG0861	Integral membrane protein TerC family
HW07_RS29320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HW07_RS29325	COG1690	Belongs to the RtcB family
HW07_RS29370	COG0700	Nucleoside recognition
HW07_RS29375	COG1301	dicarboxylic acid transport
HW07_RS29400	COG5002	protein histidine kinase activity
HW07_RS29405	COG3023	N-Acetylmuramoyl-L-alanine amidase
HW07_RS29410	COG2095	MarC family integral membrane protein
HW07_RS29435	COG3245	cytochrome
HW07_RS29470	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HW07_RS29475	COG0735	belongs to the Fur family
HW07_RS29485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HW07_RS29500	COG2011	ABC-type metal ion transport system permease component
HW07_RS29530	COG0531	amino acid
HW07_RS29540	COG4191	Histidine kinase
HW07_RS29570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW07_RS29570	COG4651	solute:proton antiporter activity
HW07_RS29575	COG1607	acyl-coa hydrolase
HW07_RS29585	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS29590	COG0174	glutamine synthetase
HW07_RS29595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HW07_RS29600	COG1028	Short-chain dehydrogenase reductase Sdr
HW07_RS29625	COG4651	solute:proton antiporter activity
HW07_RS29625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HW07_RS29630	COG0477	Major facilitator Superfamily
HW07_RS29640	COG0523	cobalamin synthesis protein
HW07_RS29685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HW07_RS29705	COG2358	TRAP transporter, solute receptor (TAXI family
HW07_RS29710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HW07_RS29730	COG1349	DNA-binding transcription factor activity
HW07_RS29790	COG1475	DNA binding
HW07_RS29795	COG1192	Involved in chromosome partitioning