locus-tag	class	description
PLES_RS00055	COG2010	Cytochrome c
PLES_RS00070	COG2818	Glycosylase
PLES_RS00085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PLES_RS00100	COG0569	domain protein
PLES_RS00120	COG1652	LysM domain
PLES_RS00125	COG0758	DNA mediated transformation
PLES_RS00155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLES_RS00175	COG3119	arylsulfatase activity
PLES_RS00180	COG0583	DNA-binding transcription factor activity
PLES_RS00215	COG3360	Dodecin
PLES_RS00230	COG3210	domain, Protein
PLES_RS00245	COG3174	membrane
PLES_RS00290	COG0367	asparagine synthase
PLES_RS00310	COG0583	DNA-binding transcription factor activity
PLES_RS00325	COG1764	response to oxidative stress
PLES_RS00360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PLES_RS00365	COG0339	signal peptide processing
PLES_RS00370	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PLES_RS00385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PLES_RS00400	COG2815	serine threonine protein kinase
PLES_RS00400	COG0515	serine threonine protein kinase
PLES_RS00405	COG0631	protein serine/threonine phosphatase activity
PLES_RS00420	COG1360	Flagellar Motor Protein
PLES_RS00545	COG0659	secondary active sulfate transmembrane transporter activity
PLES_RS00555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PLES_RS00560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PLES_RS00565	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PLES_RS00605	COG2153	protein acetylation
PLES_RS00645	COG0583	DNA-binding transcription factor activity
PLES_RS00670	COG2824	Alkylphosphonate utilization operon protein PhnA
PLES_RS00700	COG0402	S-adenosylhomocysteine deaminase activity
PLES_RS00710	COG3845	ABC transporter
PLES_RS00715	COG4603	Belongs to the binding-protein-dependent transport system permease family
PLES_RS00720	COG1079	Belongs to the binding-protein-dependent transport system permease family
PLES_RS00790	COG0583	DNA-binding transcription factor activity
PLES_RS00795	COG3485	protocatechuate 3,4-dioxygenase
PLES_RS00800	COG3485	protocatechuate 3,4-dioxygenase
PLES_RS00805	COG1414	Transcriptional regulator
PLES_RS00820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS00825	COG0583	DNA-binding transcription factor activity
PLES_RS00860	COG2233	PERMEase
PLES_RS00865	COG1309	transcriptional regulator
PLES_RS00900	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PLES_RS00915	COG0835	chemotaxis
PLES_RS00920	COG0643	Histidine kinase
PLES_RS00920	COG2198	Histidine kinase
PLES_RS00925	COG0745	RESPONSE REGULATOR receiver
PLES_RS00935	COG0583	DNA-binding transcription factor activity
PLES_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS00950	COG1116	anion transmembrane transporter activity
PLES_RS00955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS00960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS01000	COG2175	clavaminate synthase activity
PLES_RS01075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PLES_RS01105	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS01110	COG1113	amino acid transport
PLES_RS01125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLES_RS01130	COG0235	Class ii aldolase
PLES_RS01135	COG1396	sequence-specific DNA binding
PLES_RS01140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PLES_RS01145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PLES_RS01155	COG0477	Major facilitator Superfamily
PLES_RS01165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLES_RS01170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PLES_RS01175	COG0583	DNA-binding transcription factor activity
PLES_RS01195	COG0673	inositol 2-dehydrogenase activity
PLES_RS01215	COG2271	Major facilitator Superfamily
PLES_RS01225	COG1309	transcriptional regulator
PLES_RS01230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PLES_RS01240	COG0477	Major facilitator Superfamily
PLES_RS01260	COG2239	Acts as a magnesium transporter
PLES_RS01350	COG0745	RESPONSE REGULATOR receiver
PLES_RS01360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PLES_RS01375	COG0583	DNA-binding transcription factor activity
PLES_RS01380	COG2807	transmembrane transport
PLES_RS01400	COG0501	Belongs to the peptidase M48B family
PLES_RS01420	COG4208	sulfate ABC transporter
PLES_RS01430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PLES_RS01450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLES_RS01465	COG2199	diguanylate cyclase activity
PLES_RS01490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PLES_RS01495	COG0174	glutamine synthetase
PLES_RS01500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PLES_RS01505	COG0174	glutamine synthetase
PLES_RS01525	COG3842	ATPase activity
PLES_RS01530	COG1176	ABC-type spermidine putrescine transport system, permease component I
PLES_RS01535	COG1177	transmembrane transport
PLES_RS01585	COG0765	amino acid transport
PLES_RS01600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PLES_RS01605	COG0277	FAD linked oxidase domain protein
PLES_RS01610	COG0179	Fumarylacetoacetate (FAA) hydrolase
PLES_RS01620	COG3111	PFAM Bacterial OB fold (BOF) protein
PLES_RS01630	COG0531	amino acid
PLES_RS01635	COG2182	Extracellular solute-binding protein
PLES_RS01640	COG1177	transmembrane transport
PLES_RS01650	COG3842	ATPase activity
PLES_RS01655	COG3204	pilus organization
PLES_RS01660	COG2234	aminopeptidase activity
PLES_RS01680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PLES_RS01690	COG0702	epimerase
PLES_RS01730	COG0730	response to heat
PLES_RS01765	COG0584	glycerophosphoryl diester phosphodiesterase
PLES_RS01785	COG0622	Phosphoesterase
PLES_RS01790	COG2233	PERMEase
PLES_RS01805	COG0693	protein deglycase activity
PLES_RS01840	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLES_RS01850	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PLES_RS01875	COG0429	hydrolase of the alpha beta-hydrolase fold
PLES_RS01885	COG0742	ribosomal rna small subunit methyltransferase
PLES_RS01890	COG0612	Peptidase, M16
PLES_RS01895	COG0612	Peptidase, M16
PLES_RS01900	COG0552	protein localization to endoplasmic reticulum
PLES_RS01905	COG2884	Cell division ATP-binding protein ftsE
PLES_RS01910	COG2177	Part of the ABC transporter FtsEX involved in
PLES_RS01930	COG2363	Small membrane protein
PLES_RS01965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PLES_RS01980	COG2813	Specifically methylates the guanine in position
PLES_RS01980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLES_RS01990	COG1160	GTP binding
PLES_RS01995	COG1872	DUF167
PLES_RS02040	COG0626	cystathionine gamma-synthase activity
PLES_RS02105	COG0784	Response regulator, receiver
PLES_RS02105	COG2198	Histidine kinase
PLES_RS02105	COG0643	Histidine kinase
PLES_RS02135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PLES_RS02150	COG3038	cytochrome b561
PLES_RS02180	COG0513	Belongs to the DEAD box helicase family
PLES_RS02190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PLES_RS02195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PLES_RS02220	COG1309	transcriptional regulator
PLES_RS02225	COG0402	S-adenosylhomocysteine deaminase activity
PLES_RS02230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PLES_RS02255	COG1953	Uracil, thiamine, allantoin
PLES_RS02270	COG1960	acyl-CoA dehydrogenase activity
PLES_RS02275	COG0583	DNA-binding transcription factor activity
PLES_RS02285	COG0306	phosphate transporter
PLES_RS02295	COG0330	HflC and HflK could
PLES_RS02305	COG1289	transmembrane transporter activity
PLES_RS02310	COG0513	Belongs to the DEAD box helicase family
PLES_RS02320	COG4067	protein conserved in archaea
PLES_RS02320	COG0189	ligase activity
PLES_RS02330	COG0477	Major facilitator Superfamily
PLES_RS02335	COG0542	response to heat
PLES_RS02345	COG0204	Acyl-transferase
PLES_RS02355	COG0745	RESPONSE REGULATOR receiver
PLES_RS02360	COG2205	protein histidine kinase activity
PLES_RS02365	COG4452	Inner membrane protein CreD
PLES_RS02395	COG4774	siderophore transport
PLES_RS02400	COG3712	iron ion homeostasis
PLES_RS02405	COG1595	DNA-templated transcription, initiation
PLES_RS02410	COG0625	glutathione transferase activity
PLES_RS02420	COG1309	transcriptional regulator
PLES_RS02425	COG1953	Uracil, thiamine, allantoin
PLES_RS02445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLES_RS02480	COG3585	molybdate ion transport
PLES_RS02480	COG2005	Transcriptional regulator
PLES_RS02485	COG5544	Lipoprotein
PLES_RS02490	COG1040	competence protein
PLES_RS02510	COG0511	ligase activity, forming carbon-carbon bonds
PLES_RS02525	COG1984	allophanate hydrolase subunit 2
PLES_RS02540	COG3121	Chaperone
PLES_RS02555	COG1073	alpha beta
PLES_RS02555	COG2226	methyltransferase
PLES_RS02575	COG1960	acyl-CoA dehydrogenase activity
PLES_RS02580	COG1960	acyl-CoA dehydrogenase activity
PLES_RS02585	COG1960	acyl-CoA dehydrogenase activity
PLES_RS02595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PLES_RS02595	COG1648	precorrin-2 dehydrogenase activity
PLES_RS02680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PLES_RS02685	COG0583	DNA-binding transcription factor activity
PLES_RS02690	COG2258	MOSC domain
PLES_RS02700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PLES_RS02720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS02730	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PLES_RS02785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PLES_RS02790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PLES_RS02800	COG3622	Belongs to the hyi family
PLES_RS02805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PLES_RS02845	COG2081	HI0933 family
PLES_RS02850	COG1451	nucleotide metabolic process
PLES_RS02855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PLES_RS02860	COG3152	Membrane
PLES_RS02865	COG1917	Cupin 2, conserved barrel domain protein
PLES_RS02865	COG4977	sequence-specific DNA binding
PLES_RS02870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PLES_RS02965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PLES_RS02985	COG2719	SpoVR family
PLES_RS02995	COG2766	serine protein kinase
PLES_RS03045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PLES_RS03060	COG2197	response regulator
PLES_RS03070	COG3842	ATPase activity
PLES_RS03080	COG1176	ABC-type spermidine putrescine transport system, permease component I
PLES_RS03090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PLES_RS03115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PLES_RS03200	COG3179	chitinase
PLES_RS03235	COG1765	OsmC-like protein
PLES_RS03250	COG0537	adenosine 5'-monophosphoramidase activity
PLES_RS03260	COG0300	oxidoreductase activity
PLES_RS03275	COG1981	membrane
PLES_RS03305	COG0739	heme binding
PLES_RS03470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PLES_RS03595	COG2814	Major facilitator Superfamily
PLES_RS03620	COG1021	2,3-dihydroxybenzoate-AMP ligase
PLES_RS03630	COG3433	isochorismatase activity
PLES_RS03630	COG2226	methyltransferase
PLES_RS03630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PLES_RS03635	COG3433	isochorismatase activity
PLES_RS03635	COG2226	methyltransferase
PLES_RS03635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PLES_RS03645	COG1132	(ABC) transporter
PLES_RS03645	COG2375	cellular response to nickel ion
PLES_RS03730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS03735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS03745	COG2706	6-phosphogluconolactonase activity
PLES_RS03765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PLES_RS03770	COG1960	acyl-CoA dehydrogenase activity
PLES_RS03780	COG4191	Histidine kinase
PLES_RS03785	COG4566	intracellular signal transduction
PLES_RS03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS03795	COG0765	amino acid transport
PLES_RS03800	COG0765	amino acid transport
PLES_RS03820	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS03825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLES_RS03830	COG2271	Major facilitator Superfamily
PLES_RS03875	COG2226	methyltransferase
PLES_RS03885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLES_RS03900	COG0251	oxidation-reduction process
PLES_RS03910	COG0693	protein deglycase activity
PLES_RS03920	COG1959	2 iron, 2 sulfur cluster binding
PLES_RS03950	COG0154	amidase activity
PLES_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS03960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLES_RS03965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLES_RS03970	COG4592	Periplasmic binding protein
PLES_RS03975	COG1120	ATPase activity
PLES_RS03985	COG4774	siderophore transport
PLES_RS03985	COG1629	transport
PLES_RS03990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLES_RS03995	COG4991	sh3 domain protein
PLES_RS04000	COG1063	alcohol dehydrogenase
PLES_RS04010	COG0022	dehydrogenase e1 component
PLES_RS04015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PLES_RS04020	COG3199	ATP-NAD kinase
PLES_RS04030	COG3284	Transcriptional regulator
PLES_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS04190	COG1484	DNA-dependent DNA replication
PLES_RS04195	COG0305	Participates in initiation and elongation during chromosome replication
PLES_RS04240	COG3179	chitinase
PLES_RS04280	COG0740	serine-type endopeptidase activity
PLES_RS04395	COG2814	Major facilitator Superfamily
PLES_RS04400	COG1846	Transcriptional regulator
PLES_RS04410	COG3278	Belongs to the heme-copper respiratory oxidase family
PLES_RS04415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PLES_RS04425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PLES_RS04440	COG3971	2-oxopent-4-enoate hydratase activity
PLES_RS04445	COG2271	Major facilitator Superfamily
PLES_RS04455	COG3384	dioxygenase
PLES_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS04500	COG1611	Belongs to the LOG family
PLES_RS04560	COG2259	Doxx family
PLES_RS04570	COG2205	protein histidine kinase activity
PLES_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS04600	COG1063	alcohol dehydrogenase
PLES_RS04605	COG2271	Major facilitator Superfamily
PLES_RS04655	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS04660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PLES_RS04675	COG3121	Chaperone
PLES_RS04680	COG3188	usher protein
PLES_RS04700	COG2197	response regulator
PLES_RS04740	COG0531	amino acid
PLES_RS04760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PLES_RS04770	COG3047	cAMP biosynthetic process
PLES_RS04800	COG3118	belongs to the thioredoxin family
PLES_RS04805	COG2264	protein methyltransferase activity
PLES_RS04820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PLES_RS04820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PLES_RS04845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PLES_RS04850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PLES_RS04860	COG3577	Aspartyl protease
PLES_RS04885	COG0142	geranyltranstransferase activity
PLES_RS04895	COG4948	Mandelate Racemase Muconate Lactonizing
PLES_RS04915	COG1131	(ABC) transporter
PLES_RS04920	COG5002	protein histidine kinase activity
PLES_RS04940	COG0745	RESPONSE REGULATOR receiver
PLES_RS04950	COG3228	Belongs to the MtfA family
PLES_RS04955	COG0586	Pfam SNARE associated Golgi protein
PLES_RS04970	COG0456	acetyltransferase
PLES_RS04980	COG4303	Ethanolamine ammonia lyase large subunit
PLES_RS04985	COG0531	amino acid
PLES_RS04995	COG3284	Transcriptional regulator
PLES_RS05000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PLES_RS05015	COG0702	epimerase
PLES_RS05035	COG1346	cytolysis
PLES_RS05045	COG0586	Pfam SNARE associated Golgi protein
PLES_RS05085	COG0768	penicillin binding
PLES_RS05090	COG0772	Belongs to the SEDS family
PLES_RS05095	COG2951	lytic endotransglycosylase activity
PLES_RS05105	COG1686	Belongs to the peptidase S11 family
PLES_RS05135	COG2951	lytic endotransglycosylase activity
PLES_RS05170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PLES_RS05180	COG4535	Mg2 and Co2 transporter CorC
PLES_RS05190	COG1702	phosphate starvation-inducible protein PhoH
PLES_RS05220	COG0351	phosphomethylpyrimidine kinase
PLES_RS05225	COG2198	Histidine kinase
PLES_RS05225	COG0784	Response regulator, receiver
PLES_RS05225	COG2205	protein histidine kinase activity
PLES_RS05235	COG1960	acyl-CoA dehydrogenase activity
PLES_RS05245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PLES_RS05285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PLES_RS05295	COG1643	Atp-dependent helicase
PLES_RS05340	COG3416	Protein conserved in bacteria
PLES_RS05350	COG0513	Belongs to the DEAD box helicase family
PLES_RS05360	COG2197	response regulator
PLES_RS05365	COG2202	Pas domain
PLES_RS05365	COG2200	EAL domain
PLES_RS05365	COG2199	diguanylate cyclase activity
PLES_RS05370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS05370	COG2205	protein histidine kinase activity
PLES_RS05390	COG1946	Acyl-CoA thioesterase
PLES_RS05410	COG4521	taurine ABC transporter
PLES_RS05420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS05425	COG2175	clavaminate synthase activity
PLES_RS05430	COG1297	OPT oligopeptide transporter protein
PLES_RS05435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PLES_RS05450	COG1271	oxidase subunit
PLES_RS05455	COG1294	oxidase, subunit
PLES_RS05465	COG2207	Transcriptional regulator
PLES_RS05475	COG0183	Belongs to the thiolase family
PLES_RS05480	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS05505	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PLES_RS05515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PLES_RS05525	COG0521	Mo-molybdopterin cofactor biosynthetic process
PLES_RS05530	COG0303	'Molybdopterin
PLES_RS05535	COG0826	peptidase U32
PLES_RS05540	COG0826	peptidase U32
PLES_RS05545	COG3154	lipid carrier protein
PLES_RS05595	COG4772	TonB-dependent receptor
PLES_RS05600	COG3712	iron ion homeostasis
PLES_RS05605	COG1595	DNA-templated transcription, initiation
PLES_RS05615	COG0697	spore germination
PLES_RS05625	COG0583	DNA-binding transcription factor activity
PLES_RS05645	COG1566	PFAM secretion protein HlyD family protein
PLES_RS05695	COG0300	oxidoreductase activity
PLES_RS05700	COG2226	methyltransferase
PLES_RS05715	COG2197	response regulator
PLES_RS05720	COG3850	Histidine kinase
PLES_RS05730	COG2223	nitrite transmembrane transporter activity
PLES_RS05735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PLES_RS05740	COG1140	nitrate reductase beta subunit
PLES_RS05745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PLES_RS05750	COG2181	nitrate reductase activity
PLES_RS05755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLES_RS05765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS05790	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS05800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS05865	COG0583	DNA-binding transcription factor activity
PLES_RS05890	COG0490	domain, Protein
PLES_RS05890	COG0471	metal ion transport
PLES_RS05895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PLES_RS05900	COG4120	Belongs to the binding-protein-dependent transport system permease family
PLES_RS05945	COG0795	lipopolysaccharide-transporting ATPase activity
PLES_RS05950	COG0795	lipopolysaccharide-transporting ATPase activity
PLES_RS05960	COG2200	EAL domain
PLES_RS05980	COG1862	Preprotein translocase
PLES_RS05995	COG3134	Outer membrane lipoprotein
PLES_RS06010	COG1045	serine acetyltransferase
PLES_RS06100	COG0436	Aminotransferase
PLES_RS06115	COG0667	Aldo Keto reductase
PLES_RS06155	COG0739	heme binding
PLES_RS06165	COG2847	Copper chaperone PCu(A)C
PLES_RS06175	COG1335	isochorismatase
PLES_RS06190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PLES_RS06205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PLES_RS06210	COG0583	DNA-binding transcription factor activity
PLES_RS06270	COG0738	Major facilitator superfamily
PLES_RS06280	COG2130	NADP-dependent
PLES_RS06285	COG2132	Multicopper oxidase
PLES_RS06290	COG0590	tRNA wobble adenosine to inosine editing
PLES_RS06325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PLES_RS06325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PLES_RS06330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PLES_RS06335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PLES_RS06340	COG2188	Transcriptional regulator
PLES_RS06380	COG0477	Major facilitator Superfamily
PLES_RS06385	COG4536	flavin adenine dinucleotide binding
PLES_RS06395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PLES_RS06420	COG1607	acyl-coa hydrolase
PLES_RS06440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PLES_RS06465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PLES_RS06505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PLES_RS06515	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS06560	COG2197	response regulator
PLES_RS06565	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PLES_RS06585	COG0477	Major facilitator Superfamily
PLES_RS06620	COG4251	negative regulation of phosphorylation
PLES_RS06620	COG3706	GGDEF domain
PLES_RS06620	COG5001	Diguanylate cyclase
PLES_RS06620	COG2203	Gaf domain
PLES_RS06625	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PLES_RS06655	COG3064	Membrane
PLES_RS06655	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PLES_RS06655	COG1073	alpha beta
PLES_RS06670	COG2885	chlorophyll binding
PLES_RS06685	COG0789	Transcriptional regulator
PLES_RS06715	COG1801	Protein of unknown function DUF72
PLES_RS06720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PLES_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS06810	COG1393	Belongs to the ArsC family
PLES_RS06885	COG1475	DNA binding
PLES_RS06925	COG4626	Terminase
PLES_RS06925	COG1802	Transcriptional regulator
PLES_RS06955	COG1598	PFAM Uncharacterised protein family UPF0150
PLES_RS06960	COG1724	mRNA binding
PLES_RS06970	COG3179	chitinase
PLES_RS07005	COG0740	serine-type endopeptidase activity
PLES_RS07140	COG0025	NhaP-type Na H and K H
PLES_RS07145	COG0436	Aminotransferase
PLES_RS07155	COG0024	Methionine aminopeptidase
PLES_RS07235	COG1115	amino acid carrier protein
PLES_RS07285	COG2391	methyltransferase activity
PLES_RS07290	COG0583	DNA-binding transcription factor activity
PLES_RS07295	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PLES_RS07300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PLES_RS07350	COG1546	Belongs to the CinA family
PLES_RS07370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PLES_RS07375	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PLES_RS07380	COG3530	Putative quorum-sensing-regulated virulence factor
PLES_RS07395	COG1177	transmembrane transport
PLES_RS07400	COG1176	ABC-type spermidine putrescine transport system, permease component I
PLES_RS07410	COG3148	PFAM DTW domain containing protein
PLES_RS07430	COG0069	glutamate synthase activity
PLES_RS07455	COG0531	amino acid
PLES_RS07460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PLES_RS07460	COG2169	Transcriptional regulator
PLES_RS07470	COG0583	DNA-binding transcription factor activity
PLES_RS07475	COG1960	acyl-CoA dehydrogenase activity
PLES_RS07480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PLES_RS07485	COG1024	Enoyl-CoA hydratase
PLES_RS07490	COG1250	3-hydroxyacyl-CoA dehydrogenase
PLES_RS07495	COG0183	Belongs to the thiolase family
PLES_RS07505	COG0583	DNA-binding transcription factor activity
PLES_RS07540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PLES_RS07585	COG2814	Major facilitator Superfamily
PLES_RS07625	COG0583	DNA-binding transcription factor activity
PLES_RS07635	COG0084	hydrolase, TatD family'
PLES_RS07640	COG1609	Transcriptional regulator
PLES_RS07650	COG1105	Belongs to the carbohydrate kinase PfkB family
PLES_RS07655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PLES_RS07655	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PLES_RS07655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PLES_RS07765	COG3842	ATPase activity
PLES_RS07785	COG0243	molybdopterin cofactor binding
PLES_RS07790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PLES_RS07795	COG2223	nitrite transmembrane transporter activity
PLES_RS07810	COG0450	alkyl hydroperoxide reductase
PLES_RS07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS07875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PLES_RS07880	COG2264	protein methyltransferase activity
PLES_RS07890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PLES_RS07945	COG0489	protein tyrosine kinase activity
PLES_RS07990	COG0791	NLP P60 protein
PLES_RS08005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PLES_RS08010	COG0668	transmembrane transport
PLES_RS08015	COG0477	Major facilitator Superfamily
PLES_RS08020	COG0513	Belongs to the DEAD box helicase family
PLES_RS08080	COG4396	Host-nuclease inhibitor protein Gam
PLES_RS08160	COG4383	Mu-like prophage protein gp29
PLES_RS08165	COG2369	cell adhesion
PLES_RS08170	COG5005	Phage virion morphogenesis
PLES_RS08200	COG4397	Mu-like prophage major head subunit gpT
PLES_RS08295	COG5002	protein histidine kinase activity
PLES_RS08295	COG0784	Response regulator, receiver
PLES_RS08295	COG2205	protein histidine kinase activity
PLES_RS08300	COG1363	Peptidase, m42
PLES_RS08305	COG0189	ligase activity
PLES_RS08305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PLES_RS08310	COG0367	asparagine synthase
PLES_RS08335	COG0183	Belongs to the thiolase family
PLES_RS08355	COG0450	alkyl hydroperoxide reductase
PLES_RS08360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS08365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS08375	COG0431	NADPH-dependent FMN reductase
PLES_RS08380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS08390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS08415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PLES_RS08440	COG0583	DNA-binding transcription factor activity
PLES_RS08445	COG1380	Effector of murein hydrolase LrgA
PLES_RS08450	COG1346	cytolysis
PLES_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS08475	COG1024	Enoyl-CoA hydratase
PLES_RS08485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PLES_RS08530	COG0508	dehydrogenase complex catalyzes the overall conversion of
PLES_RS08570	COG1629	transport
PLES_RS08625	COG0583	DNA-binding transcription factor activity
PLES_RS08700	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PLES_RS08705	COG3639	organic phosphonate transmembrane transporter activity
PLES_RS08710	COG2188	Transcriptional regulator
PLES_RS08715	COG3624	Phosphonate C-P lyase system protein PhnG
PLES_RS08725	COG3626	phosphonate metabolism
PLES_RS08730	COG3627	carbon phosphorus lyase activity
PLES_RS08735	COG4107	phosphonate C-P lyase system protein PhnK
PLES_RS08740	COG4778	phosphonate C-P lyase system protein PhnL
PLES_RS08745	COG3454	Phosphonate metabolism
PLES_RS08755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PLES_RS08855	COG0697	spore germination
PLES_RS08880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PLES_RS08900	COG0784	Response regulator, receiver
PLES_RS08900	COG0835	chemotaxis
PLES_RS08915	COG0745	RESPONSE REGULATOR receiver
PLES_RS08925	COG0514	ATP-dependent DNA helicase (RecQ)
PLES_RS08930	COG2203	Gaf domain
PLES_RS08930	COG5001	Diguanylate cyclase
PLES_RS08930	COG4251	negative regulation of phosphorylation
PLES_RS08930	COG3706	GGDEF domain
PLES_RS08950	COG1752	Esterase of the alpha-beta hydrolase superfamily
PLES_RS08990	COG2124	cytochrome p450
PLES_RS08995	COG4221	oxidoreductase activity
PLES_RS09040	COG0583	DNA-binding transcription factor activity
PLES_RS09070	COG3639	organic phosphonate transmembrane transporter activity
PLES_RS09080	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PLES_RS09085	COG2084	Dehydrogenase
PLES_RS09100	COG0589	response to stress
PLES_RS09140	COG2814	Major facilitator Superfamily
PLES_RS09145	COG2030	dehydratase
PLES_RS09150	COG2267	carboxylic ester hydrolase activity
PLES_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS09160	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS09170	COG1643	Atp-dependent helicase
PLES_RS09180	COG0537	adenosine 5'-monophosphoramidase activity
PLES_RS09230	COG1595	DNA-templated transcription, initiation
PLES_RS09300	COG1201	RNA secondary structure unwinding
PLES_RS09305	COG0784	Response regulator, receiver
PLES_RS09305	COG2205	protein histidine kinase activity
PLES_RS09320	COG4772	TonB-dependent receptor
PLES_RS09335	COG2076	Multidrug Resistance protein
PLES_RS09340	COG0385	Bile acid
PLES_RS09390	COG2200	EAL domain
PLES_RS09400	COG0604	alcohol dehydrogenase
PLES_RS09400	COG3321	synthase
PLES_RS09405	COG0560	Phosphoserine phosphatase
PLES_RS09420	COG1176	ABC-type spermidine putrescine transport system, permease component I
PLES_RS09450	COG0564	pseudouridine synthase activity
PLES_RS09460	COG2894	cell division
PLES_RS09470	COG1560	Kdo2-lipid A biosynthetic process
PLES_RS09485	COG2853	Lipoprotein
PLES_RS09505	COG3162	membrane
PLES_RS09510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLES_RS09540	COG1132	(ABC) transporter
PLES_RS09550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PLES_RS09575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PLES_RS09590	COG0438	transferase activity, transferring glycosyl groups
PLES_RS09590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PLES_RS09620	COG1127	ABC transporter
PLES_RS09625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PLES_RS09630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PLES_RS09635	COG0727	PFAM Uncharacterised protein family (UPF0153)
PLES_RS09640	COG0778	Nitroreductase
PLES_RS09660	COG0745	RESPONSE REGULATOR receiver
PLES_RS09670	COG2350	Protein conserved in bacteria
PLES_RS09680	COG0613	PHP domain protein
PLES_RS09685	COG0009	L-threonylcarbamoyladenylate synthase
PLES_RS09695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PLES_RS09740	COG1175	transmembrane transport
PLES_RS09745	COG0395	ABC-type sugar transport system, permease component
PLES_RS09750	COG3842	ATPase activity
PLES_RS09760	COG0676	glucose-6-phosphate 1-epimerase activity
PLES_RS09805	COG0786	glutamate:sodium symporter activity
PLES_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS09835	COG0402	S-adenosylhomocysteine deaminase activity
PLES_RS09865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PLES_RS09915	COG0367	asparagine synthase
PLES_RS09920	COG0438	transferase activity, transferring glycosyl groups
PLES_RS09925	COG0438	transferase activity, transferring glycosyl groups
PLES_RS09935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PLES_RS09975	COG0583	DNA-binding transcription factor activity
PLES_RS10010	COG0596	Alpha beta hydrolase
PLES_RS10015	COG0800	Aldolase
PLES_RS10030	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS10050	COG0583	DNA-binding transcription factor activity
PLES_RS10055	COG0251	oxidation-reduction process
PLES_RS10075	COG2226	methyltransferase
PLES_RS10115	COG0285	dihydrofolate synthase activity
PLES_RS10120	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PLES_RS10125	COG1286	toxin biosynthetic process
PLES_RS10225	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLES_RS10225	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS10250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PLES_RS10260	COG3139	Protein of unknown function (DUF1315)
PLES_RS10270	COG0308	aminopeptidase N
PLES_RS10300	COG0745	RESPONSE REGULATOR receiver
PLES_RS10335	COG0714	Associated with various cellular activities
PLES_RS10355	COG1335	isochorismatase
PLES_RS10365	COG2342	PFAM TM1410 hypothetical-related protein
PLES_RS10390	COG0297	glycogen (starch) synthase activity
PLES_RS10440	COG3130	regulation of translation
PLES_RS10450	COG2027	D-alanyl-D-alanine carboxypeptidase
PLES_RS10455	COG3171	Protein conserved in bacteria
PLES_RS10460	COG2197	response regulator
PLES_RS10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS10465	COG2205	protein histidine kinase activity
PLES_RS10490	COG0004	ammonium transporteR
PLES_RS10500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PLES_RS10510	COG0625	glutathione transferase activity
PLES_RS10515	COG1309	transcriptional regulator
PLES_RS10545	COG0521	Mo-molybdopterin cofactor biosynthetic process
PLES_RS10565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PLES_RS10570	COG1070	Carbohydrate kinase
PLES_RS10590	COG0741	lytic transglycosylase activity
PLES_RS10595	COG0488	(ABC) transporter
PLES_RS10605	COG0589	response to stress
PLES_RS10680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PLES_RS10690	COG1113	amino acid transport
PLES_RS10725	COG1477	protein flavinylation
PLES_RS10740	COG0584	glycerophosphoryl diester phosphodiesterase
PLES_RS10755	COG4591	ABC-type transport system involved in lipoprotein release permease component
PLES_RS10775	COG0658	competence protein
PLES_RS10775	COG2333	competence protein COMEC
PLES_RS10780	COG0811	peptide transport
PLES_RS10785	COG0848	biopolymer transport protein
PLES_RS10805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PLES_RS10815	COG1530	ribonuclease E activity
PLES_RS10830	COG0616	signal peptide processing
PLES_RS10830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PLES_RS10840	COG1399	metal-binding, possibly nucleic acid-binding protein
PLES_RS10870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PLES_RS10880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PLES_RS10900	COG0084	hydrolase, TatD family'
PLES_RS10985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PLES_RS11000	COG0183	Belongs to the thiolase family
PLES_RS11010	COG2233	PERMEase
PLES_RS11020	COG3038	cytochrome b561
PLES_RS11035	COG2814	Major facilitator Superfamily
PLES_RS11040	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS11045	COG1309	transcriptional regulator
PLES_RS11080	COG4160	amino acid transport
PLES_RS11085	COG4215	(ABC) transporter
PLES_RS11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS11095	COG1473	amidohydrolase
PLES_RS11100	COG0583	DNA-binding transcription factor activity
PLES_RS11105	COG0840	transmembrane signaling receptor activity
PLES_RS11135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLES_RS11145	COG1120	ATPase activity
PLES_RS11175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PLES_RS11205	COG3047	cAMP biosynthetic process
PLES_RS11205	COG2885	chlorophyll binding
PLES_RS11210	COG2197	response regulator
PLES_RS11220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PLES_RS11225	COG1595	DNA-templated transcription, initiation
PLES_RS11240	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS11255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PLES_RS11260	COG1960	acyl-CoA dehydrogenase activity
PLES_RS11265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PLES_RS11280	COG1309	transcriptional regulator
PLES_RS11310	COG0583	DNA-binding transcription factor activity
PLES_RS11320	COG0583	DNA-binding transcription factor activity
PLES_RS11330	COG0714	Associated with various cellular activities
PLES_RS11375	COG0084	hydrolase, TatD family'
PLES_RS11380	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PLES_RS11385	COG2259	Doxx family
PLES_RS11400	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PLES_RS11415	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PLES_RS11420	COG4181	ATPase activity
PLES_RS11460	COG1764	response to oxidative stress
PLES_RS11465	COG1846	Transcriptional regulator
PLES_RS11470	COG0583	DNA-binding transcription factor activity
PLES_RS11480	COG0583	DNA-binding transcription factor activity
PLES_RS11490	COG3214	Protein conserved in bacteria
PLES_RS11495	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PLES_RS11505	COG1024	Enoyl-CoA hydratase
PLES_RS11515	COG3384	dioxygenase
PLES_RS11555	COG2866	Carboxypeptidase
PLES_RS11570	COG0436	Aminotransferase
PLES_RS11580	COG0386	Belongs to the glutathione peroxidase family
PLES_RS11585	COG1846	Transcriptional regulator
PLES_RS11590	COG5002	protein histidine kinase activity
PLES_RS11590	COG2205	protein histidine kinase activity
PLES_RS11590	COG0784	Response regulator, receiver
PLES_RS11595	COG2255	four-way junction helicase activity
PLES_RS11600	COG1956	GAF domain-containing protein
PLES_RS11605	COG0625	glutathione transferase activity
PLES_RS11700	COG0625	glutathione transferase activity
PLES_RS11705	COG1131	(ABC) transporter
PLES_RS11710	COG0842	Transport permease protein
PLES_RS11755	COG2188	Transcriptional regulator
PLES_RS11765	COG2853	Lipoprotein
PLES_RS11775	COG0745	RESPONSE REGULATOR receiver
PLES_RS11795	COG1335	isochorismatase
PLES_RS11825	COG5434	Belongs to the glycosyl hydrolase 28 family
PLES_RS11855	COG3655	Transcriptional regulator
PLES_RS11895	COG2116	formate transmembrane transporter activity
PLES_RS11900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS11965	COG1024	Enoyl-CoA hydratase
PLES_RS11965	COG1250	3-hydroxyacyl-CoA dehydrogenase
PLES_RS11975	COG2837	iron assimilation
PLES_RS12060	COG1238	metal cluster binding
PLES_RS12070	COG1295	ribonuclease BN
PLES_RS12100	COG0024	Methionine aminopeptidase
PLES_RS12175	COG2963	transposase activity
PLES_RS12180	COG2801	Transposase and inactivated derivatives
PLES_RS12285	COG0582	viral genome integration into host DNA
PLES_RS12315	COG2801	Transposase and inactivated derivatives
PLES_RS12320	COG2963	transposase activity
PLES_RS12355	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PLES_RS12355	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PLES_RS12365	COG0542	response to heat
PLES_RS12400	COG0789	Transcriptional regulator
PLES_RS12410	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLES_RS12410	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS12415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PLES_RS12420	COG0243	molybdopterin cofactor binding
PLES_RS12440	COG1280	lysine exporter protein (LysE YggA)
PLES_RS12455	COG0542	response to heat
PLES_RS12525	COG1607	acyl-coa hydrolase
PLES_RS12530	COG1959	2 iron, 2 sulfur cluster binding
PLES_RS12545	COG2819	hydrolase of the alpha beta superfamily
PLES_RS12590	COG0583	DNA-binding transcription factor activity
PLES_RS12600	COG4106	trans-aconitate 2-methyltransferase activity
PLES_RS12610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PLES_RS12615	COG1459	type II secretion system
PLES_RS12625	COG2165	general secretion pathway protein
PLES_RS12665	COG0720	synthase
PLES_RS12670	COG3604	Transcriptional regulator
PLES_RS12730	COG0840	transmembrane signaling receptor activity
PLES_RS12735	COG2056	Na+-H+ antiporter family
PLES_RS12755	COG2226	methyltransferase
PLES_RS12850	COG2153	protein acetylation
PLES_RS12855	COG2850	peptidyl-arginine hydroxylation
PLES_RS12895	COG1278	Cold shock
PLES_RS12905	COG0542	response to heat
PLES_RS12910	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PLES_RS12925	COG0492	ferredoxin-NADP+ reductase activity
PLES_RS12940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PLES_RS12955	COG0435	Glutathione S-transferase
PLES_RS12965	COG2920	part of a sulfur-relay system
PLES_RS13050	COG1475	DNA binding
PLES_RS13075	COG2932	Transcriptional regulator
PLES_RS13200	COG1802	Transcriptional regulator
PLES_RS13200	COG4626	Terminase
PLES_RS13205	COG4695	Portal protein
PLES_RS13210	COG0740	serine-type endopeptidase activity
PLES_RS13310	COG3179	chitinase
PLES_RS13350	COG0583	DNA-binding transcription factor activity
PLES_RS13355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLES_RS13360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS13370	COG1960	acyl-CoA dehydrogenase activity
PLES_RS13375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS13385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS13390	COG3424	synthase
PLES_RS13430	COG1960	acyl-CoA dehydrogenase activity
PLES_RS13435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PLES_RS13445	COG1309	transcriptional regulator
PLES_RS13455	COG1131	(ABC) transporter
PLES_RS13460	COG0842	Transport permease protein
PLES_RS13465	COG0842	Transport permease protein
PLES_RS13490	COG2197	response regulator
PLES_RS13495	COG4771	TonB-dependent receptor
PLES_RS13535	COG0582	viral genome integration into host DNA
PLES_RS13545	COG1396	sequence-specific DNA binding
PLES_RS13550	COG0583	DNA-binding transcription factor activity
PLES_RS13560	COG1522	sequence-specific DNA binding
PLES_RS13575	COG0633	Ferredoxin
PLES_RS13580	COG0789	Transcriptional regulator
PLES_RS13590	COG0640	Transcriptional regulator
PLES_RS13595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PLES_RS13625	COG1937	Protein conserved in bacteria
PLES_RS13630	COG2814	Major facilitator Superfamily
PLES_RS13635	COG1230	cation diffusion facilitator family transporter
PLES_RS13640	COG0640	Transcriptional regulator
PLES_RS13680	COG2814	Major facilitator Superfamily
PLES_RS13695	COG2814	Major facilitator Superfamily
PLES_RS13710	COG2186	Transcriptional regulator
PLES_RS13730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PLES_RS13780	COG2003	Belongs to the UPF0758 family
PLES_RS13835	COG3311	Transcriptional regulator
PLES_RS13840	COG1569	PIN domain
PLES_RS13995	COG0789	Transcriptional regulator
PLES_RS14035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PLES_RS14045	COG0789	Transcriptional regulator
PLES_RS14060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PLES_RS14065	COG0629	single-stranded DNA binding
PLES_RS14120	COG0784	Response regulator, receiver
PLES_RS14120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS14120	COG2198	Histidine kinase
PLES_RS14120	COG2205	protein histidine kinase activity
PLES_RS14140	COG2249	NAD(P)H dehydrogenase (quinone) activity
PLES_RS14155	COG1522	sequence-specific DNA binding
PLES_RS14185	COG4191	Histidine kinase
PLES_RS14210	COG3706	GGDEF domain
PLES_RS14210	COG4251	negative regulation of phosphorylation
PLES_RS14210	COG5001	Diguanylate cyclase
PLES_RS14210	COG2203	Gaf domain
PLES_RS14220	COG0659	secondary active sulfate transmembrane transporter activity
PLES_RS14255	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS14265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PLES_RS14275	COG0183	Belongs to the thiolase family
PLES_RS14280	COG1960	acyl-CoA dehydrogenase activity
PLES_RS14330	COG0729	surface antigen
PLES_RS14340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PLES_RS14345	COG2267	carboxylic ester hydrolase activity
PLES_RS14350	COG2453	phosphatase
PLES_RS14350	COG0671	phosphoesterase, PA-phosphatase related
PLES_RS14365	COG4589	Belongs to the CDS family
PLES_RS14370	COG0667	Aldo Keto reductase
PLES_RS14380	COG1115	amino acid carrier protein
PLES_RS14390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PLES_RS14410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS14415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS14420	COG1538	Outer membrane efflux protein
PLES_RS14480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PLES_RS14480	COG0543	2 iron, 2 sulfur cluster binding
PLES_RS14485	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PLES_RS14490	COG4638	Rieske (2fe-2S)
PLES_RS14505	COG4948	Mandelate Racemase Muconate Lactonizing
PLES_RS14515	COG3485	protocatechuate 3,4-dioxygenase
PLES_RS14550	COG2807	transmembrane transport
PLES_RS14555	COG0590	tRNA wobble adenosine to inosine editing
PLES_RS14570	COG2318	DinB family
PLES_RS14630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLES_RS14635	COG2863	cytochrome
PLES_RS14640	COG3258	Cytochrome c
PLES_RS14645	COG0642	Histidine kinase
PLES_RS14680	COG0625	glutathione transferase activity
PLES_RS14700	COG0583	DNA-binding transcription factor activity
PLES_RS14705	COG1595	DNA-templated transcription, initiation
PLES_RS14710	COG3712	iron ion homeostasis
PLES_RS14735	COG3210	domain, Protein
PLES_RS14770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PLES_RS14780	COG2382	esterase
PLES_RS14800	COG0583	DNA-binding transcription factor activity
PLES_RS14820	COG1760	l-serine dehydratase
PLES_RS14825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PLES_RS14860	COG2217	Heavy metal translocating P-type atpase
PLES_RS14875	COG0583	DNA-binding transcription factor activity
PLES_RS14890	COG1566	PFAM secretion protein HlyD family protein
PLES_RS14950	COG1335	isochorismatase
PLES_RS14960	COG0583	DNA-binding transcription factor activity
PLES_RS15000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PLES_RS15005	COG1121	(ABC) transporter
PLES_RS15130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS15155	COG0735	belongs to the Fur family
PLES_RS15165	COG1304	FMN binding
PLES_RS15195	COG4566	intracellular signal transduction
PLES_RS15285	COG3829	transcription factor binding
PLES_RS15310	COG3829	transcription factor binding
PLES_RS15315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PLES_RS15320	COG0584	glycerophosphoryl diester phosphodiesterase
PLES_RS15325	COG2011	ABC-type metal ion transport system permease component
PLES_RS15335	COG1464	Belongs to the NlpA lipoprotein family
PLES_RS15360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PLES_RS15365	COG1070	Carbohydrate kinase
PLES_RS15370	COG0246	Mannitol dehydrogenase
PLES_RS15385	COG1175	transmembrane transport
PLES_RS15405	COG4771	TonB-dependent receptor
PLES_RS15420	COG1917	Cupin 2, conserved barrel domain protein
PLES_RS15420	COG4977	sequence-specific DNA binding
PLES_RS15435	COG1116	anion transmembrane transporter activity
PLES_RS15440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PLES_RS15445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS15465	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS15475	COG3265	gluconokinase activity
PLES_RS15480	COG1609	Transcriptional regulator
PLES_RS15490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS15495	COG0583	DNA-binding transcription factor activity
PLES_RS15515	COG1396	sequence-specific DNA binding
PLES_RS15525	COG2175	clavaminate synthase activity
PLES_RS15535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PLES_RS15540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS15565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PLES_RS15565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PLES_RS15575	COG3469	chitinase activity
PLES_RS15580	COG2188	Transcriptional regulator
PLES_RS15585	COG1053	succinate dehydrogenase
PLES_RS15600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PLES_RS15630	COG4772	TonB-dependent receptor
PLES_RS15675	COG0431	NADPH-dependent FMN reductase
PLES_RS15680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PLES_RS15690	COG0640	Transcriptional regulator
PLES_RS15695	COG2207	Transcriptional regulator
PLES_RS15700	COG1064	alcohol dehydrogenase
PLES_RS15725	COG1309	transcriptional regulator
PLES_RS15735	COG2329	Antibiotic biosynthesis monooxygenase
PLES_RS15770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PLES_RS15780	COG1609	Transcriptional regulator
PLES_RS15810	COG0252	asparaginase activity
PLES_RS15815	COG1115	amino acid carrier protein
PLES_RS15860	COG1053	succinate dehydrogenase
PLES_RS15870	COG0728	peptidoglycan biosynthetic process
PLES_RS15930	COG2258	MOSC domain
PLES_RS15955	COG2508	Transcriptional regulator
PLES_RS15965	COG4447	cellulose binding
PLES_RS15970	COG2409	Drug exporters of the RND superfamily
PLES_RS15990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS16005	COG2072	flavoprotein involved in K transport
PLES_RS16020	COG0531	amino acid
PLES_RS16025	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS16030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PLES_RS16045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLES_RS16050	COG3162	membrane
PLES_RS16055	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS16090	COG3008	intermembrane lipid transfer
PLES_RS16095	COG2995	paraquat-inducible protein a
PLES_RS16100	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS16110	COG4948	Mandelate Racemase Muconate Lactonizing
PLES_RS16115	COG2271	Major facilitator Superfamily
PLES_RS16130	COG3618	amidohydrolase
PLES_RS16135	COG2271	Major facilitator Superfamily
PLES_RS16170	COG0765	amino acid transport
PLES_RS16175	COG0765	amino acid transport
PLES_RS16190	COG2084	Dehydrogenase
PLES_RS16200	COG2130	NADP-dependent
PLES_RS16205	COG1309	transcriptional regulator
PLES_RS16225	COG0366	Alpha amylase catalytic
PLES_RS16230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
PLES_RS16250	COG1063	alcohol dehydrogenase
PLES_RS16265	COG3546	catalase activity
PLES_RS16270	COG3685	Protein conserved in bacteria
PLES_RS16295	COG2890	protein-(glutamine-N5) methyltransferase activity
PLES_RS16310	COG4191	Histidine kinase
PLES_RS16310	COG0784	Response regulator, receiver
PLES_RS16340	COG1363	Peptidase, m42
PLES_RS16380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PLES_RS16420	COG3568	Endonuclease Exonuclease Phosphatase
PLES_RS16425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PLES_RS16430	COG0392	lysyltransferase activity
PLES_RS16440	COG0366	Alpha amylase catalytic
PLES_RS16460	COG1285	pathogenesis
PLES_RS16480	COG0058	SHG alpha-glucan phosphorylase activity
PLES_RS16495	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS16500	COG1546	Belongs to the CinA family
PLES_RS16530	COG2323	membrane
PLES_RS16550	COG3121	Chaperone
PLES_RS16560	COG3188	usher protein
PLES_RS16565	COG3121	Chaperone
PLES_RS16575	COG3969	phosphoadenosine phosphosulfate
PLES_RS16585	COG1475	DNA binding
PLES_RS16590	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS16595	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PLES_RS16600	COG0583	DNA-binding transcription factor activity
PLES_RS16620	COG1063	alcohol dehydrogenase
PLES_RS16630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PLES_RS16630	COG2169	Transcriptional regulator
PLES_RS16645	COG0583	DNA-binding transcription factor activity
PLES_RS16650	COG2814	Major facilitator Superfamily
PLES_RS16670	COG1984	allophanate hydrolase subunit 2
PLES_RS16680	COG0028	Belongs to the TPP enzyme family
PLES_RS16690	COG0300	oxidoreductase activity
PLES_RS16725	COG2814	Major facilitator Superfamily
PLES_RS16735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PLES_RS16755	COG0596	Alpha beta hydrolase
PLES_RS16760	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PLES_RS16765	COG0367	asparagine synthase
PLES_RS16775	COG1522	sequence-specific DNA binding
PLES_RS16790	COG1113	amino acid transport
PLES_RS16795	COG2010	Cytochrome c
PLES_RS16800	COG2010	Cytochrome c
PLES_RS16820	COG3153	acetyltransferase
PLES_RS16820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PLES_RS16825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PLES_RS16830	COG5001	Diguanylate cyclase
PLES_RS16840	COG4206	TonB-dependent receptor
PLES_RS16845	COG2192	nodulation
PLES_RS16850	COG2814	Major facilitator Superfamily
PLES_RS16880	COG1104	cysteine desulfurase activity
PLES_RS16885	COG4172	Belongs to the ABC transporter superfamily
PLES_RS16890	COG4239	(ABC) transporter, permease
PLES_RS16895	COG4174	ABC transporter (Permease)
PLES_RS16905	COG4771	TonB-dependent receptor
PLES_RS16920	COG0583	DNA-binding transcription factor activity
PLES_RS16940	COG1595	DNA-templated transcription, initiation
PLES_RS16955	COG2207	Transcriptional regulator
PLES_RS16975	COG0564	pseudouridine synthase activity
PLES_RS16985	COG0531	amino acid
PLES_RS16990	COG0174	glutamine synthetase
PLES_RS17015	COG0028	Belongs to the TPP enzyme family
PLES_RS17030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PLES_RS17050	COG1522	sequence-specific DNA binding
PLES_RS17095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS17100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS17110	COG3204	pilus organization
PLES_RS17115	COG0789	Transcriptional regulator
PLES_RS17120	COG1960	acyl-CoA dehydrogenase activity
PLES_RS17125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PLES_RS17155	COG0179	Fumarylacetoacetate (FAA) hydrolase
PLES_RS17165	COG2271	Major facilitator Superfamily
PLES_RS17170	COG3829	transcription factor binding
PLES_RS17170	COG3290	protein histidine kinase activity
PLES_RS17175	COG2610	gluconate transmembrane transporter activity
PLES_RS17180	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS17185	COG2031	fatty acid transporter
PLES_RS17200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PLES_RS17205	COG0583	DNA-binding transcription factor activity
PLES_RS17210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PLES_RS17215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLES_RS17235	COG2205	protein histidine kinase activity
PLES_RS17300	COG3851	Histidine kinase
PLES_RS17315	COG2205	protein histidine kinase activity
PLES_RS17315	COG0784	Response regulator, receiver
PLES_RS17335	COG2194	sulfuric ester hydrolase activity
PLES_RS17380	COG0488	(ABC) transporter
PLES_RS17395	COG0583	DNA-binding transcription factor activity
PLES_RS17400	COG1278	Cold shock
PLES_RS17450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PLES_RS17455	COG1609	Transcriptional regulator
PLES_RS17460	COG1172	Belongs to the binding-protein-dependent transport system permease family
PLES_RS17465	COG1129	ABC transporter
PLES_RS17475	COG2204	response regulator
PLES_RS17490	COG2010	Cytochrome c
PLES_RS17495	COG0753	catalase activity
PLES_RS17530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PLES_RS17535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PLES_RS17540	COG2080	2 iron, 2 sulfur cluster binding
PLES_RS17565	COG1944	ATP diphosphatase activity
PLES_RS17585	COG4771	TonB-dependent receptor
PLES_RS17590	COG0275	rRNA processing
PLES_RS17595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PLES_RS17595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLES_RS17610	COG0579	oxidoreductase
PLES_RS17640	COG1595	DNA-templated transcription, initiation
PLES_RS17645	COG3712	iron ion homeostasis
PLES_RS17665	COG2814	Major facilitator Superfamily
PLES_RS17715	COG2197	response regulator
PLES_RS17740	COG2366	antibiotic biosynthetic process
PLES_RS17755	COG0625	glutathione transferase activity
PLES_RS17770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLES_RS17775	COG0417	DNA replication proofreading
PLES_RS17820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS17890	COG1309	transcriptional regulator
PLES_RS17910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PLES_RS17915	COG0583	DNA-binding transcription factor activity
PLES_RS17925	COG2354	Protein conserved in bacteria
PLES_RS17930	COG3278	Belongs to the heme-copper respiratory oxidase family
PLES_RS17940	COG2239	Acts as a magnesium transporter
PLES_RS17955	COG4251	negative regulation of phosphorylation
PLES_RS17955	COG5001	Diguanylate cyclase
PLES_RS17955	COG3706	GGDEF domain
PLES_RS17955	COG2203	Gaf domain
PLES_RS17960	COG4977	sequence-specific DNA binding
PLES_RS17965	COG3813	Protein conserved in bacteria
PLES_RS18030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PLES_RS18055	COG0604	alcohol dehydrogenase
PLES_RS18060	COG0616	signal peptide processing
PLES_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS18085	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS18090	COG0583	DNA-binding transcription factor activity
PLES_RS18115	COG1024	Enoyl-CoA hydratase
PLES_RS18125	COG0531	amino acid
PLES_RS18140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PLES_RS18160	COG0741	lytic transglycosylase activity
PLES_RS18160	COG1388	LysM domain
PLES_RS18165	COG4166	transmembrane transport
PLES_RS18170	COG4166	transmembrane transport
PLES_RS18175	COG4174	ABC transporter (Permease)
PLES_RS18180	COG4239	(ABC) transporter, permease
PLES_RS18185	COG4172	Belongs to the ABC transporter superfamily
PLES_RS18195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PLES_RS18210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PLES_RS18230	COG0745	RESPONSE REGULATOR receiver
PLES_RS18235	COG2205	protein histidine kinase activity
PLES_RS18240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PLES_RS18290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PLES_RS18310	COG0589	response to stress
PLES_RS18330	COG2201	protein-glutamate methylesterase activity
PLES_RS18340	COG2223	nitrite transmembrane transporter activity
PLES_RS18345	COG0515	serine threonine protein kinase
PLES_RS18350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PLES_RS18355	COG2146	nitrite reductase [NAD(P)H] activity
PLES_RS18360	COG0243	molybdopterin cofactor binding
PLES_RS18380	COG0668	transmembrane transport
PLES_RS18420	COG0189	ligase activity
PLES_RS18420	COG4067	protein conserved in archaea
PLES_RS18460	COG2909	trisaccharide binding
PLES_RS18465	COG2909	trisaccharide binding
PLES_RS18500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PLES_RS18555	COG0519	Catalyzes the synthesis of GMP from XMP
PLES_RS18570	COG0667	Aldo Keto reductase
PLES_RS18585	COG0183	Belongs to the thiolase family
PLES_RS18605	COG1305	Transglutaminase-like
PLES_RS18615	COG2308	Evidence 4 Homologs of previously reported genes of
PLES_RS18640	COG1317	bacterial-type flagellum organization
PLES_RS18750	COG4789	Type iii secretion
PLES_RS18800	COG4790	Type iii secretion
PLES_RS18805	COG4794	Type iii secretion
PLES_RS18810	COG4791	protein targeting
PLES_RS18815	COG4792	protein secretion
PLES_RS18895	COG2840	Smr protein MutS2
PLES_RS18915	COG0515	serine threonine protein kinase
PLES_RS18915	COG2815	serine threonine protein kinase
PLES_RS18955	COG2204	response regulator
PLES_RS18995	COG0625	glutathione transferase activity
PLES_RS19000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PLES_RS19015	COG3135	benzoate transporter
PLES_RS19030	COG2130	NADP-dependent
PLES_RS19040	COG0840	transmembrane signaling receptor activity
PLES_RS19050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PLES_RS19090	COG0745	RESPONSE REGULATOR receiver
PLES_RS19095	COG2205	protein histidine kinase activity
PLES_RS19120	COG1960	acyl-CoA dehydrogenase activity
PLES_RS19130	COG1024	Enoyl-CoA hydratase
PLES_RS19140	COG2186	Transcriptional regulator
PLES_RS19145	COG2807	transmembrane transport
PLES_RS19150	COG0628	permease
PLES_RS19160	COG0625	glutathione transferase activity
PLES_RS19190	COG1022	Amp-dependent synthetase and ligase
PLES_RS19220	COG0784	Response regulator, receiver
PLES_RS19220	COG2205	protein histidine kinase activity
PLES_RS19220	COG5002	protein histidine kinase activity
PLES_RS19260	COG1846	Transcriptional regulator
PLES_RS19265	COG2080	2 iron, 2 sulfur cluster binding
PLES_RS19270	COG2010	Cytochrome c
PLES_RS19270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PLES_RS19275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PLES_RS19275	COG2010	Cytochrome c
PLES_RS19280	COG2207	Transcriptional regulator
PLES_RS19355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PLES_RS19360	COG1053	succinate dehydrogenase
PLES_RS19365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PLES_RS19370	COG2009	succinate dehydrogenase
PLES_RS19400	COG2084	Dehydrogenase
PLES_RS19415	COG3738	Protein conserved in bacteria
PLES_RS19440	COG0251	oxidation-reduction process
PLES_RS19445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS19450	COG0174	glutamine synthetase
PLES_RS19455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS19475	COG0840	transmembrane signaling receptor activity
PLES_RS19490	COG3278	Belongs to the heme-copper respiratory oxidase family
PLES_RS19505	COG2010	Cytochrome c
PLES_RS19510	COG3278	Belongs to the heme-copper respiratory oxidase family
PLES_RS19525	COG2010	Cytochrome c
PLES_RS19530	COG0348	domain, Protein
PLES_RS19540	COG2217	Heavy metal translocating P-type atpase
PLES_RS19580	COG2076	Multidrug Resistance protein
PLES_RS19610	COG1960	acyl-CoA dehydrogenase activity
PLES_RS19625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PLES_RS19650	COG1196	nuclear chromosome segregation
PLES_RS19680	COG0402	S-adenosylhomocysteine deaminase activity
PLES_RS19685	COG1247	-acetyltransferase
PLES_RS19705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PLES_RS19710	COG0384	phenazine biosynthesis protein PhzF
PLES_RS19750	COG5006	permease, DMT superfamily
PLES_RS19765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PLES_RS19780	COG3795	YCII-related domain
PLES_RS19790	COG2814	Major facilitator Superfamily
PLES_RS19795	COG4941	Belongs to the sigma-70 factor family
PLES_RS19805	COG3795	YCII-related domain
PLES_RS19815	COG2197	response regulator
PLES_RS19820	COG1982	Orn Lys Arg decarboxylase major
PLES_RS19825	COG0189	ligase activity
PLES_RS19830	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS19845	COG0765	amino acid transport
PLES_RS19850	COG0765	amino acid transport
PLES_RS19855	COG1126	abc transporter atp-binding protein
PLES_RS19880	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS19895	COG1253	flavin adenine dinucleotide binding
PLES_RS19900	COG0300	oxidoreductase activity
PLES_RS19910	COG0583	DNA-binding transcription factor activity
PLES_RS19915	COG3591	Belongs to the peptidase S1B family
PLES_RS19915	COG1864	DNA RNA non-specific endonuclease
PLES_RS19920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PLES_RS19925	COG4319	ketosteroid isomerase
PLES_RS19940	COG4774	siderophore transport
PLES_RS19985	COG2814	Major facilitator Superfamily
PLES_RS20005	COG0583	DNA-binding transcription factor activity
PLES_RS20015	COG0121	glutamine amidotransferase
PLES_RS20045	COG3712	iron ion homeostasis
PLES_RS20050	COG1595	DNA-templated transcription, initiation
PLES_RS20065	COG1230	cation diffusion facilitator family transporter
PLES_RS20070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PLES_RS20095	COG2252	PERMEase
PLES_RS20155	COG2233	PERMEase
PLES_RS20170	COG1309	transcriptional regulator
PLES_RS20180	COG3960	tartronate-semialdehyde synthase activity
PLES_RS20185	COG3622	Belongs to the hyi family
PLES_RS20190	COG2084	Dehydrogenase
PLES_RS20200	COG0469	pyruvate kinase activity
PLES_RS20205	COG4413	Urea transporter
PLES_RS20210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PLES_RS20225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PLES_RS20235	COG3192	ethanolamine utilization protein
PLES_RS20250	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLES_RS20255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PLES_RS20330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PLES_RS20345	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS20350	COG1496	oxidoreductase activity
PLES_RS20375	COG0835	chemotaxis
PLES_RS20385	COG1192	Involved in chromosome partitioning
PLES_RS20390	COG1360	Flagellar Motor Protein
PLES_RS20395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PLES_RS20405	COG0784	Response regulator, receiver
PLES_RS20405	COG2198	Histidine kinase
PLES_RS20405	COG0643	Histidine kinase
PLES_RS20435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PLES_RS20440	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PLES_RS20460	COG1987	bacterial-type flagellum assembly
PLES_RS20500	COG2832	Protein of unknown function (DUF454)
PLES_RS20515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS20520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS20530	COG3300	MHYT domain
PLES_RS20530	COG5001	Diguanylate cyclase
PLES_RS20565	COG0488	(ABC) transporter
PLES_RS20620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PLES_RS20625	COG0583	DNA-binding transcription factor activity
PLES_RS20640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PLES_RS20650	COG3264	Mechanosensitive ion channel
PLES_RS20650	COG1196	nuclear chromosome segregation
PLES_RS20655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PLES_RS20655	COG0116	Belongs to the methyltransferase superfamily
PLES_RS20665	COG0210	DNA helicase
PLES_RS20690	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PLES_RS20765	COG1960	acyl-CoA dehydrogenase activity
PLES_RS20785	COG0406	alpha-ribazole phosphatase activity
PLES_RS20815	COG0778	Nitroreductase
PLES_RS20830	COG4206	TonB-dependent receptor
PLES_RS20840	COG1802	Transcriptional regulator
PLES_RS20850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS20880	COG0477	Major facilitator Superfamily
PLES_RS20900	COG0765	amino acid transport
PLES_RS20910	COG1126	abc transporter atp-binding protein
PLES_RS20920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PLES_RS20925	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS20975	COG4191	Histidine kinase
PLES_RS20975	COG0784	Response regulator, receiver
PLES_RS21015	COG1289	transmembrane transporter activity
PLES_RS21030	COG2207	Transcriptional regulator
PLES_RS21050	COG2249	NAD(P)H dehydrogenase (quinone) activity
PLES_RS21055	COG2249	NAD(P)H dehydrogenase (quinone) activity
PLES_RS21065	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PLES_RS21095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PLES_RS21105	COG0318	PFAM AMP-dependent synthetase and ligase
PLES_RS21110	COG0367	asparagine synthase
PLES_RS21120	COG2211	Major facilitator Superfamily
PLES_RS21170	COG1335	isochorismatase
PLES_RS21175	COG0583	DNA-binding transcription factor activity
PLES_RS21185	COG0791	NLP P60 protein
PLES_RS21190	COG0791	NLP P60 protein
PLES_RS21200	COG3829	transcription factor binding
PLES_RS21215	COG2818	Glycosylase
PLES_RS21225	COG4974	Belongs to the 'phage' integrase family
PLES_RS21235	COG4128	Pfam Zonular occludens toxin
PLES_RS21315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PLES_RS21320	COG1960	acyl-CoA dehydrogenase activity
PLES_RS21330	COG0625	glutathione transferase activity
PLES_RS21350	COG5001	Diguanylate cyclase
PLES_RS21350	COG3447	MASE1 domain protein
PLES_RS21350	COG5002	protein histidine kinase activity
PLES_RS21370	COG4459	periplasmic nitrate reductase
PLES_RS21375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLES_RS21375	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PLES_RS21380	COG3062	negative regulation of establishment of protein localization
PLES_RS21390	COG3043	anaerobic respiration
PLES_RS21395	COG3005	denitrification pathway
PLES_RS21400	COG2951	lytic endotransglycosylase activity
PLES_RS21405	COG0861	Integral membrane protein TerC family
PLES_RS21410	COG0753	catalase activity
PLES_RS21430	COG2977	Belongs to the P-Pant transferase superfamily
PLES_RS21435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PLES_RS21450	COG2226	methyltransferase
PLES_RS21465	COG2205	protein histidine kinase activity
PLES_RS21470	COG0745	RESPONSE REGULATOR receiver
PLES_RS21475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLES_RS21475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PLES_RS21480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PLES_RS21485	COG1943	Transposase
PLES_RS21515	COG0531	amino acid
PLES_RS21545	COG0583	DNA-binding transcription factor activity
PLES_RS21550	COG3257	ureidoglycine aminohydrolase activity
PLES_RS21565	COG0604	alcohol dehydrogenase
PLES_RS21565	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS21565	COG3321	synthase
PLES_RS21570	COG2197	response regulator
PLES_RS21610	COG0583	DNA-binding transcription factor activity
PLES_RS21615	COG0667	Aldo Keto reductase
PLES_RS21640	COG0242	peptide deformylase activity
PLES_RS21650	COG2199	diguanylate cyclase activity
PLES_RS21655	COG2885	chlorophyll binding
PLES_RS21685	COG1132	(ABC) transporter
PLES_RS21695	COG4628	conserved protein (DUF2132)
PLES_RS21700	COG2133	pyrroloquinoline quinone binding
PLES_RS21715	COG2207	Transcriptional regulator
PLES_RS21720	COG0477	Major facilitator Superfamily
PLES_RS21735	COG2882	bacterial-type flagellum organization
PLES_RS21795	COG1334	flagellar protein FlaG
PLES_RS21855	COG4787	bacterial-type flagellum-dependent cell motility
PLES_RS21865	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PLES_RS21875	COG1815	bacterial-type flagellum-dependent cell motility
PLES_RS21920	COG0326	Molecular chaperone. Has ATPase activity
PLES_RS21935	COG3189	MarR family transcriptional regulator
PLES_RS21955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PLES_RS21970	COG2212	antiporter activity
PLES_RS21975	COG1863	multisubunit Na H antiporter MnhE subunit
PLES_RS21980	COG0651	ATP synthesis coupled electron transport
PLES_RS21985	COG1006	Multisubunit Na H antiporter MnhC subunit
PLES_RS21990	COG2111	Na H antiporter
PLES_RS21990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PLES_RS21995	COG3133	Outer membrane lipoprotein
PLES_RS22005	COG1929	Belongs to the glycerate kinase type-1 family
PLES_RS22010	COG2610	gluconate transmembrane transporter activity
PLES_RS22015	COG3835	regulator
PLES_RS22025	COG2885	chlorophyll binding
PLES_RS22040	COG1199	ATP-dependent helicase activity
PLES_RS22080	COG2860	membrane
PLES_RS22095	COG0653	protein targeting
PLES_RS22100	COG0625	glutathione transferase activity
PLES_RS22125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS22130	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS22150	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS22155	COG1960	acyl-CoA dehydrogenase activity
PLES_RS22160	COG1024	Enoyl-CoA hydratase
PLES_RS22165	COG1960	acyl-CoA dehydrogenase activity
PLES_RS22175	COG2814	Major facilitator Superfamily
PLES_RS22180	COG2030	dehydratase
PLES_RS22190	COG0183	Belongs to the thiolase family
PLES_RS22220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PLES_RS22225	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PLES_RS22240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PLES_RS22250	COG0425	Belongs to the sulfur carrier protein TusA family
PLES_RS22305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PLES_RS22310	COG3188	usher protein
PLES_RS22330	COG1051	belongs to the nudix hydrolase family
PLES_RS22355	COG0602	queuosine metabolic process
PLES_RS22360	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PLES_RS22390	COG0824	Thioesterase
PLES_RS22420	COG0783	Belongs to the Dps family
PLES_RS22465	COG3118	belongs to the thioredoxin family
PLES_RS22500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PLES_RS22515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PLES_RS22555	COG3122	Protein conserved in bacteria
PLES_RS22565	COG3956	TIGRFAM MazG family protein
PLES_RS22570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PLES_RS22600	COG0784	Response regulator, receiver
PLES_RS22600	COG2205	protein histidine kinase activity
PLES_RS22600	COG5002	protein histidine kinase activity
PLES_RS22605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PLES_RS22655	COG3038	cytochrome b561
PLES_RS22670	COG4807	Protein conserved in bacteria
PLES_RS22680	COG2239	Acts as a magnesium transporter
PLES_RS22750	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PLES_RS22845	COG2301	Belongs to the HpcH HpaI aldolase family
PLES_RS22855	COG2079	MmgE PrpD family protein
PLES_RS22865	COG1960	acyl-CoA dehydrogenase activity
PLES_RS22870	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PLES_RS22875	COG0583	DNA-binding transcription factor activity
PLES_RS22880	COG0583	DNA-binding transcription factor activity
PLES_RS22930	COG1113	amino acid transport
PLES_RS22950	COG0604	alcohol dehydrogenase
PLES_RS22950	COG3321	synthase
PLES_RS22950	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS22960	COG5002	protein histidine kinase activity
PLES_RS22960	COG5001	Diguanylate cyclase
PLES_RS22980	COG0271	Belongs to the BolA IbaG family
PLES_RS23020	COG0492	ferredoxin-NADP+ reductase activity
PLES_RS23025	COG0450	alkyl hydroperoxide reductase
PLES_RS23060	COG1307	EDD domain protein, DegV family
PLES_RS23070	COG1309	transcriptional regulator
PLES_RS23075	COG0386	Belongs to the glutathione peroxidase family
PLES_RS23095	COG0204	Acyl-transferase
PLES_RS23100	COG2885	chlorophyll binding
PLES_RS23105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PLES_RS23160	COG2801	Transposase and inactivated derivatives
PLES_RS23165	COG2963	transposase activity
PLES_RS23210	COG2267	carboxylic ester hydrolase activity
PLES_RS23255	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
PLES_RS23290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PLES_RS23305	COG0546	phosphoglycolate phosphatase activity
PLES_RS23320	COG3023	N-Acetylmuramoyl-L-alanine amidase
PLES_RS23335	COG0656	L-ascorbic acid biosynthetic process
PLES_RS23360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PLES_RS23370	COG1802	Transcriptional regulator
PLES_RS23380	COG0372	Belongs to the citrate synthase family
PLES_RS23395	COG2079	MmgE PrpD family protein
PLES_RS23410	COG1113	amino acid transport
PLES_RS23440	COG0583	DNA-binding transcription factor activity
PLES_RS23445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PLES_RS23455	COG4206	TonB-dependent receptor
PLES_RS23465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PLES_RS23530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLES_RS23610	COG3180	Ammonia monooxygenase
PLES_RS23620	COG2720	vancomycin resistance protein
PLES_RS23635	COG1960	acyl-CoA dehydrogenase activity
PLES_RS23640	COG1024	Enoyl-CoA hydratase
PLES_RS23660	COG2910	NAD(P)H-binding
PLES_RS23665	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PLES_RS23765	COG0583	DNA-binding transcription factor activity
PLES_RS23780	COG0463	Glycosyl transferase, family 2
PLES_RS23785	COG0154	amidase activity
PLES_RS23805	COG0583	DNA-binding transcription factor activity
PLES_RS23850	COG2831	hemolysin activation secretion protein
PLES_RS23995	COG0420	3'-5' exonuclease activity
PLES_RS24005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PLES_RS24010	COG1074	ATP-dependent DNA helicase activity
PLES_RS24015	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PLES_RS24020	COG0095	Lipoate-protein ligase
PLES_RS24025	COG0697	spore germination
PLES_RS24040	COG0840	transmembrane signaling receptor activity
PLES_RS24050	COG0306	phosphate transporter
PLES_RS24110	COG4964	Belongs to the GSP D family
PLES_RS24150	COG0788	formyltetrahydrofolate deformylase activity
PLES_RS24160	COG2925	Exonuclease
PLES_RS24190	COG0714	Associated with various cellular activities
PLES_RS24220	COG0589	response to stress
PLES_RS24230	COG1024	Enoyl-CoA hydratase
PLES_RS24240	COG3706	GGDEF domain
PLES_RS24260	COG0693	protein deglycase activity
PLES_RS24275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PLES_RS24290	COG0154	amidase activity
PLES_RS24300	COG1473	amidohydrolase
PLES_RS24315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PLES_RS24320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PLES_RS24320	COG0426	domain, Protein
PLES_RS24340	COG0589	response to stress
PLES_RS24355	COG2814	Major facilitator Superfamily
PLES_RS24360	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS24375	COG1918	ferrous iron import across plasma membrane
PLES_RS24390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PLES_RS24430	COG1704	LemA family
PLES_RS24455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS24460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS24475	COG3642	lipopolysaccharide core region biosynthetic process
PLES_RS24485	COG2205	protein histidine kinase activity
PLES_RS24490	COG0745	RESPONSE REGULATOR receiver
PLES_RS24525	COG3030	protein affecting phage T7 exclusion by the F plasmid
PLES_RS24535	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS24560	COG0668	transmembrane transport
PLES_RS24570	COG0745	RESPONSE REGULATOR receiver
PLES_RS24585	COG2096	Adenosyltransferase
PLES_RS24590	COG0494	nUDIX hydrolase
PLES_RS24610	COG0739	heme binding
PLES_RS24610	COG1196	nuclear chromosome segregation
PLES_RS24610	COG0741	lytic transglycosylase activity
PLES_RS24655	COG0772	Belongs to the SEDS family
PLES_RS24670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PLES_RS24705	COG3107	peptidoglycan biosynthetic process
PLES_RS24720	COG2823	Periplasmic or secreted lipoprotein
PLES_RS24725	COG2969	positive regulation of protein catabolic process
PLES_RS24730	COG0625	glutathione transferase activity
PLES_RS24735	COG2857	Cytochrome c1
PLES_RS24740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PLES_RS24745	COG0723	plastoquinol--plastocyanin reductase activity
PLES_RS24760	COG0667	Aldo Keto reductase
PLES_RS24765	COG1960	acyl-CoA dehydrogenase activity
PLES_RS24780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PLES_RS24790	COG2945	thiolester hydrolase activity
PLES_RS24810	COG2951	lytic endotransglycosylase activity
PLES_RS24820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PLES_RS24860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PLES_RS24865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PLES_RS24870	COG1127	ABC transporter
PLES_RS24880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PLES_RS24895	COG1137	ATPase activity
PLES_RS24950	COG0312	modulator of DNA gyrase
PLES_RS24960	COG0312	modulator of DNA gyrase
PLES_RS24965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PLES_RS24975	COG1530	ribonuclease E activity
PLES_RS24990	COG1792	Involved in formation and maintenance of cell shape
PLES_RS24995	COG1077	Cell shape determining protein MreB Mrl
PLES_RS25015	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PLES_RS25020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PLES_RS25025	COG4676	Protein conserved in bacteria
PLES_RS25030	COG5445	Predicted secreted protein (DUF2300)
PLES_RS25045	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PLES_RS25050	COG4676	Protein conserved in bacteria
PLES_RS25055	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PLES_RS25070	COG0747	negative chemotaxis
PLES_RS25075	COG0747	negative chemotaxis
PLES_RS25090	COG0747	negative chemotaxis
PLES_RS25100	COG0747	negative chemotaxis
PLES_RS25105	COG0601	transmembrane transport
PLES_RS25110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PLES_RS25115	COG0444	Belongs to the ABC transporter superfamily
PLES_RS25120	COG4608	Belongs to the ABC transporter superfamily
PLES_RS25135	COG1984	allophanate hydrolase subunit 2
PLES_RS25155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PLES_RS25160	COG4774	siderophore transport
PLES_RS25175	COG2194	sulfuric ester hydrolase activity
PLES_RS25185	COG0019	diaminopimelate decarboxylase activity
PLES_RS25225	COG4969	Belongs to the N-Me-Phe pilin family
PLES_RS25290	COG1252	NADH dehydrogenase
PLES_RS25295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PLES_RS25370	COG4969	Belongs to the N-Me-Phe pilin family
PLES_RS25410	COG1047	Peptidyl-prolyl cis-trans
PLES_RS25425	COG0196	riboflavin kinase activity
PLES_RS25440	COG3045	CreA protein
PLES_RS25465	COG0142	geranyltranstransferase activity
PLES_RS25480	COG0545	Peptidyl-prolyl cis-trans isomerase
PLES_RS25500	COG1067	ATP-dependent peptidase activity
PLES_RS25525	COG4650	regulator
PLES_RS25540	COG1690	Belongs to the RtcB family
PLES_RS25545	COG3541	Predicted nucleotidyltransferase
PLES_RS25565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PLES_RS25590	COG0577	efflux transmembrane transporter activity
PLES_RS25590	COG1136	(ABC) transporter
PLES_RS25595	COG1136	(ABC) transporter
PLES_RS25595	COG0577	efflux transmembrane transporter activity
PLES_RS25600	COG0488	(ABC) transporter
PLES_RS25620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PLES_RS25625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS25650	COG0523	cobalamin synthesis protein
PLES_RS25655	COG2879	small protein
PLES_RS25660	COG1966	Carbon starvation protein
PLES_RS25730	COG3608	succinylglutamate desuccinylase aspartoacylase
PLES_RS25730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PLES_RS25735	COG2010	Cytochrome c
PLES_RS25770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PLES_RS25780	COG0833	amino acid
PLES_RS25785	COG2119	membrane
PLES_RS25800	COG0501	Belongs to the peptidase M48B family
PLES_RS25805	COG0840	transmembrane signaling receptor activity
PLES_RS25810	COG2135	peptidase activity
PLES_RS25815	COG1285	pathogenesis
PLES_RS25875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PLES_RS25930	COG1090	epimerase
PLES_RS25935	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PLES_RS25945	COG0789	Transcriptional regulator
PLES_RS25965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PLES_RS26020	COG0012	GTP binding
PLES_RS26040	COG0288	reversible hydration of carbon dioxide
PLES_RS26050	COG0456	acetyltransferase
PLES_RS26095	COG1840	ABC-type Fe3 transport system, periplasmic component
PLES_RS26100	COG3008	intermembrane lipid transfer
PLES_RS26105	COG2995	paraquat-inducible protein a
PLES_RS26110	COG2995	paraquat-inducible protein a
PLES_RS26150	COG1183	phosphatidylcholine synthase activity
PLES_RS26165	COG0028	Belongs to the TPP enzyme family
PLES_RS26175	COG3098	single-species biofilm formation
PLES_RS26185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PLES_RS26220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PLES_RS26225	COG4558	Periplasmic binding protein
PLES_RS26230	COG3720	iron ion transport
PLES_RS26235	COG4771	TonB-dependent receptor
PLES_RS26260	COG0436	Aminotransferase
PLES_RS26270	COG2321	neutral zinc metallopeptidase
PLES_RS26280	COG2252	PERMEase
PLES_RS26295	COG0436	Aminotransferase
PLES_RS26300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PLES_RS26315	COG4191	Histidine kinase
PLES_RS26415	COG0195	Participates in both transcription termination and antitermination
PLES_RS26450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PLES_RS26515	COG0497	DNA recombination
PLES_RS26545	COG2186	Transcriptional regulator
PLES_RS26550	COG1620	l-lactate permease
PLES_RS26600	COG0697	spore germination
PLES_RS26620	COG0697	spore germination
PLES_RS26625	COG1522	sequence-specific DNA binding
PLES_RS26655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PLES_RS26685	COG0509	glycine decarboxylation via glycine cleavage system
PLES_RS26725	COG0531	amino acid
PLES_RS26740	COG3276	selenocysteine insertion sequence binding
PLES_RS26755	COG2864	formate dehydrogenase
PLES_RS26760	COG0437	4 iron, 4 sulfur cluster binding
PLES_RS26765	COG3383	formate dehydrogenase (NAD+) activity
PLES_RS26765	COG0243	molybdopterin cofactor binding
PLES_RS26770	COG3383	formate dehydrogenase (NAD+) activity
PLES_RS26770	COG0243	molybdopterin cofactor binding
PLES_RS26775	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PLES_RS26780	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS26780	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLES_RS26805	COG0463	Glycosyl transferase, family 2
PLES_RS26815	COG0534	Mate efflux family protein
PLES_RS26825	COG1283	sodium-dependent phosphate transmembrane transporter activity
PLES_RS26850	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PLES_RS26875	COG4221	oxidoreductase activity
PLES_RS26880	COG1272	protein, Hemolysin III
PLES_RS26915	COG0023	Translation Initiation Factor
PLES_RS27000	COG2095	MarC family integral membrane protein
PLES_RS27005	COG0683	leucine binding
PLES_RS27020	COG0411	ABC transporter
PLES_RS27065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PLES_RS27080	COG0443	Heat shock 70 kDa protein
PLES_RS27105	COG0789	Transcriptional regulator
PLES_RS27110	COG2982	Protein involved in outer membrane biogenesis
PLES_RS27115	COG2193	ferroxidase activity
PLES_RS27125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PLES_RS27130	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PLES_RS27190	COG3712	iron ion homeostasis
PLES_RS27195	COG1595	DNA-templated transcription, initiation
PLES_RS27215	COG2814	Major facilitator Superfamily
PLES_RS27225	COG0583	DNA-binding transcription factor activity
PLES_RS27250	COG4221	oxidoreductase activity
PLES_RS27255	COG2423	ornithine cyclodeaminase activity
PLES_RS27285	COG0583	DNA-binding transcription factor activity
PLES_RS27300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PLES_RS27340	COG0668	transmembrane transport
PLES_RS27360	COG3300	MHYT domain
PLES_RS27360	COG5001	Diguanylate cyclase
PLES_RS27370	COG0305	Participates in initiation and elongation during chromosome replication
PLES_RS27400	COG0557	exoribonuclease II activity
PLES_RS27430	COG0330	HflC and HflK could
PLES_RS27435	COG0330	HflC and HflK could
PLES_RS27440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PLES_RS27460	COG0860	N-Acetylmuramoyl-L-alanine amidase
PLES_RS27465	COG0802	atpase or kinase
PLES_RS27470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PLES_RS27470	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PLES_RS27520	COG5001	Diguanylate cyclase
PLES_RS27520	COG3300	MHYT domain
PLES_RS27525	COG0560	Phosphoserine phosphatase
PLES_RS27525	COG3830	Belongs to the UPF0237 family
PLES_RS27535	COG1988	membrane-bound metal-dependent
PLES_RS27550	COG3577	Aspartyl protease
PLES_RS27565	COG3150	esterase
PLES_RS27570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PLES_RS27580	COG0494	nUDIX hydrolase
PLES_RS27595	COG1538	Outer membrane efflux protein
PLES_RS27600	COG2249	NAD(P)H dehydrogenase (quinone) activity
PLES_RS27615	COG0045	succinate-CoA ligase (ADP-forming) activity
PLES_RS27620	COG1960	acyl-CoA dehydrogenase activity
PLES_RS27625	COG1024	Enoyl-CoA hydratase
PLES_RS27630	COG0833	amino acid
PLES_RS27660	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLES_RS27660	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS27670	COG1519	Transferase
PLES_RS27675	COG0583	DNA-binding transcription factor activity
PLES_RS27690	COG0667	Aldo Keto reductase
PLES_RS27700	COG1960	acyl-CoA dehydrogenase activity
PLES_RS27705	COG1960	acyl-CoA dehydrogenase activity
PLES_RS27710	COG0367	asparagine synthase
PLES_RS27735	COG1215	transferase activity, transferring glycosyl groups
PLES_RS27755	COG0438	transferase activity, transferring glycosyl groups
PLES_RS27760	COG2192	nodulation
PLES_RS27785	COG0438	transferase activity, transferring glycosyl groups
PLES_RS27790	COG0859	PFAM glycosyl transferase family 9
PLES_RS27795	COG0859	PFAM glycosyl transferase family 9
PLES_RS27830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PLES_RS27835	COG1960	acyl-CoA dehydrogenase activity
PLES_RS27845	COG3264	Mechanosensitive ion channel
PLES_RS27845	COG1196	nuclear chromosome segregation
PLES_RS27855	COG0730	response to heat
PLES_RS27860	COG2873	o-acetylhomoserine
PLES_RS27875	COG1192	Involved in chromosome partitioning
PLES_RS27880	COG0583	DNA-binding transcription factor activity
PLES_RS27885	COG2814	Major facilitator Superfamily
PLES_RS27910	COG0493	'glutamate synthase
PLES_RS27915	COG0069	glutamate synthase activity
PLES_RS27915	COG0067	glutamate synthase
PLES_RS27915	COG0070	glutamate synthase
PLES_RS27965	COG0281	malic enzyme
PLES_RS27985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PLES_RS28095	COG0840	transmembrane signaling receptor activity
PLES_RS28105	COG1126	abc transporter atp-binding protein
PLES_RS28110	COG0765	amino acid transport
PLES_RS28140	COG1051	belongs to the nudix hydrolase family
PLES_RS28145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PLES_RS28150	COG0251	oxidation-reduction process
PLES_RS28175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PLES_RS28195	COG2986	histidine ammonia-lyase
PLES_RS28200	COG4175	Glycine betaine
PLES_RS28205	COG4176	ABC-type proline glycine betaine transport system permease component
PLES_RS28225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PLES_RS28260	COG0402	S-adenosylhomocysteine deaminase activity
PLES_RS28310	COG0789	Transcriptional regulator
PLES_RS28315	COG1217	gtp-binding protein TYPA
PLES_RS28335	COG0668	transmembrane transport
PLES_RS28350	COG3852	Histidine kinase
PLES_RS28365	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PLES_RS28400	COG4942	peptidase
PLES_RS28405	COG0793	Belongs to the peptidase S41A family
PLES_RS28410	COG2861	carbohydrate metabolic process
PLES_RS28470	COG0579	oxidoreductase
PLES_RS28480	COG1194	a g-specific adenine glycosylase
PLES_RS28490	COG0673	inositol 2-dehydrogenase activity
PLES_RS28500	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS28535	COG1846	Transcriptional regulator
PLES_RS28545	COG1566	PFAM secretion protein HlyD family protein
PLES_RS28550	COG2814	Major facilitator Superfamily
PLES_RS28560	COG1088	dTDP-glucose 4,6-dehydratase activity
PLES_RS28565	COG1091	dTDP-4-dehydrorhamnose reductase activity
PLES_RS28630	COG1218	3'(2'),5'-bisphosphate nucleotidase
PLES_RS28635	COG0494	nUDIX hydrolase
PLES_RS28640	COG1011	Hydrolase
PLES_RS28645	COG1652	LysM domain
PLES_RS28655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PLES_RS28675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PLES_RS28685	COG0824	Thioesterase
PLES_RS28690	COG1454	alcohol dehydrogenase
PLES_RS28695	COG1960	acyl-CoA dehydrogenase activity
PLES_RS28700	COG1250	3-hydroxyacyl-CoA dehydrogenase
PLES_RS28700	COG1024	Enoyl-CoA hydratase
PLES_RS28710	COG0778	Nitroreductase
PLES_RS28735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PLES_RS28740	COG0189	ligase activity
PLES_RS28740	COG4067	protein conserved in archaea
PLES_RS28765	COG2183	response to ionizing radiation
PLES_RS28795	COG0306	phosphate transporter
PLES_RS28800	COG1392	Phosphate transport regulator
PLES_RS28805	COG3025	triphosphatase activity
PLES_RS28810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PLES_RS28840	COG1178	ABC-type Fe3 transport system permease component
PLES_RS28850	COG0583	DNA-binding transcription factor activity
PLES_RS28865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PLES_RS28875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PLES_RS28880	COG0006	proline dipeptidase activity
PLES_RS28900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PLES_RS28910	COG0842	Transport permease protein
PLES_RS28915	COG1129	ABC transporter
PLES_RS28915	COG0842	Transport permease protein
PLES_RS28920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PLES_RS28935	COG2271	Major facilitator Superfamily
PLES_RS28950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PLES_RS28950	COG2755	lipolytic protein G-D-S-L family
PLES_RS28980	COG0586	Pfam SNARE associated Golgi protein
PLES_RS28985	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PLES_RS28990	COG2050	protein possibly involved in aromatic compounds catabolism
PLES_RS29000	COG0672	)-iron permease
PLES_RS29005	COG1280	lysine exporter protein (LysE YggA)
PLES_RS29010	COG0861	Integral membrane protein TerC family
PLES_RS29020	COG0488	(ABC) transporter
PLES_RS29075	COG3275	phosphorelay sensor kinase activity
PLES_RS29105	COG0598	Magnesium transport protein CorA
PLES_RS29135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PLES_RS29195	COG0432	Pfam Uncharacterised protein family UPF0047
PLES_RS29200	COG0004	ammonium transporteR
PLES_RS29205	COG0347	Belongs to the P(II) protein family
PLES_RS29215	COG0606	chelatase, subunit chli
PLES_RS29220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PLES_RS29230	COG0583	DNA-binding transcription factor activity
PLES_RS29245	COG0210	DNA helicase
PLES_RS29250	COG0028	Belongs to the TPP enzyme family
PLES_RS29260	COG0427	acetyl-CoA hydrolase
PLES_RS29270	COG1917	Cupin 2, conserved barrel domain protein
PLES_RS29270	COG1396	sequence-specific DNA binding
PLES_RS29280	COG0251	oxidation-reduction process
PLES_RS29310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PLES_RS29315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PLES_RS29320	COG2814	Major facilitator Superfamily
PLES_RS29325	COG1012	belongs to the aldehyde dehydrogenase family
PLES_RS29330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PLES_RS29350	COG0747	negative chemotaxis
PLES_RS29365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PLES_RS29405	COG3245	cytochrome
PLES_RS29425	COG0708	Exodeoxyribonuclease III
PLES_RS29440	COG1561	YicC-like family, N-terminal region
PLES_RS29455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PLES_RS29485	COG0583	DNA-binding transcription factor activity
PLES_RS29490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PLES_RS29525	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PLES_RS29530	COG0247	lactate metabolic process
PLES_RS29535	COG0277	FAD linked oxidase domain protein
PLES_RS29540	COG0277	FAD linked oxidase domain protein
PLES_RS29545	COG2186	Transcriptional regulator
PLES_RS29575	COG1253	flavin adenine dinucleotide binding
PLES_RS29580	COG0739	heme binding
PLES_RS29600	COG0573	inorganic phosphate transmembrane transporter activity
PLES_RS29640	COG0477	Major facilitator Superfamily
PLES_RS29645	COG1607	acyl-coa hydrolase
PLES_RS29665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PLES_RS29670	COG4175	Glycine betaine
PLES_RS29675	COG4176	ABC-type proline glycine betaine transport system permease component
PLES_RS29685	COG1760	l-serine dehydratase
PLES_RS29700	COG0583	DNA-binding transcription factor activity
PLES_RS29710	COG0657	acetylesterase activity
PLES_RS29725	COG3246	L-lysine catabolic process to acetate
PLES_RS29780	COG1902	pentaerythritol trinitrate reductase activity
PLES_RS29780	COG0446	pyridine nucleotide-disulphide oxidoreductase
PLES_RS29785	COG0247	lactate metabolic process
PLES_RS29785	COG2181	nitrate reductase activity
PLES_RS29805	COG3655	Transcriptional regulator
PLES_RS29845	COG1017	nitric oxide dioxygenase activity
PLES_RS29845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PLES_RS29930	COG0583	DNA-binding transcription factor activity
PLES_RS29940	COG2391	methyltransferase activity
PLES_RS29965	COG5016	pyruvate
PLES_RS29965	COG0511	ligase activity, forming carbon-carbon bonds
PLES_RS29970	COG0439	Biotin carboxylase
PLES_RS29975	COG0583	DNA-binding transcription factor activity
PLES_RS29990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PLES_RS29995	COG0826	peptidase U32
PLES_RS30015	COG0210	DNA helicase
PLES_RS30025	COG0427	acetyl-CoA hydrolase
PLES_RS30040	COG0438	transferase activity, transferring glycosyl groups
PLES_RS30085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PLES_RS30090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PLES_RS30090	COG2755	lipolytic protein G-D-S-L family
PLES_RS30130	COG0679	Auxin Efflux Carrier
PLES_RS30140	COG2851	Citrate transporter
PLES_RS30145	COG0861	Integral membrane protein TerC family
PLES_RS30150	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PLES_RS30155	COG1690	Belongs to the RtcB family
PLES_RS30190	COG0700	Nucleoside recognition
PLES_RS30195	COG1301	dicarboxylic acid transport
PLES_RS30220	COG5002	protein histidine kinase activity
PLES_RS30225	COG3023	N-Acetylmuramoyl-L-alanine amidase
PLES_RS30230	COG2095	MarC family integral membrane protein
PLES_RS30255	COG3245	cytochrome
PLES_RS30290	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PLES_RS30295	COG0735	belongs to the Fur family
PLES_RS30305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PLES_RS30320	COG2011	ABC-type metal ion transport system permease component
PLES_RS30350	COG0531	amino acid
PLES_RS30360	COG4191	Histidine kinase
PLES_RS30395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PLES_RS30395	COG4651	solute:proton antiporter activity
PLES_RS30400	COG1607	acyl-coa hydrolase
PLES_RS30410	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS30415	COG0174	glutamine synthetase
PLES_RS30420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PLES_RS30425	COG1028	Short-chain dehydrogenase reductase Sdr
PLES_RS30450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PLES_RS30450	COG4651	solute:proton antiporter activity
PLES_RS30455	COG0477	Major facilitator Superfamily
PLES_RS30465	COG0523	cobalamin synthesis protein
PLES_RS30510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PLES_RS30530	COG2358	TRAP transporter, solute receptor (TAXI family
PLES_RS30535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PLES_RS30555	COG1349	DNA-binding transcription factor activity
PLES_RS30615	COG1475	DNA binding
PLES_RS30620	COG1192	Involved in chromosome partitioning