locus-tag	class	description
PAM18_RS00035	COG2010	Cytochrome c
PAM18_RS00050	COG2818	Glycosylase
PAM18_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PAM18_RS00080	COG0569	domain protein
PAM18_RS00100	COG1652	LysM domain
PAM18_RS00105	COG0758	DNA mediated transformation
PAM18_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAM18_RS00155	COG3119	arylsulfatase activity
PAM18_RS00160	COG0583	DNA-binding transcription factor activity
PAM18_RS00195	COG3360	Dodecin
PAM18_RS00225	COG3174	membrane
PAM18_RS00290	COG0583	DNA-binding transcription factor activity
PAM18_RS00305	COG1764	response to oxidative stress
PAM18_RS00340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PAM18_RS00345	COG0339	signal peptide processing
PAM18_RS00350	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PAM18_RS00365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PAM18_RS00385	COG0631	protein serine/threonine phosphatase activity
PAM18_RS00400	COG1360	Flagellar Motor Protein
PAM18_RS00525	COG0659	secondary active sulfate transmembrane transporter activity
PAM18_RS00535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PAM18_RS00540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAM18_RS00545	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PAM18_RS00585	COG2153	protein acetylation
PAM18_RS00625	COG0583	DNA-binding transcription factor activity
PAM18_RS00650	COG2824	Alkylphosphonate utilization operon protein PhnA
PAM18_RS00680	COG0402	S-adenosylhomocysteine deaminase activity
PAM18_RS00690	COG3845	ABC transporter
PAM18_RS00695	COG4603	Belongs to the binding-protein-dependent transport system permease family
PAM18_RS00700	COG1079	Belongs to the binding-protein-dependent transport system permease family
PAM18_RS00770	COG0583	DNA-binding transcription factor activity
PAM18_RS00775	COG3485	protocatechuate 3,4-dioxygenase
PAM18_RS00780	COG3485	protocatechuate 3,4-dioxygenase
PAM18_RS00785	COG1414	Transcriptional regulator
PAM18_RS00800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS00805	COG0583	DNA-binding transcription factor activity
PAM18_RS00840	COG2233	PERMEase
PAM18_RS00845	COG1309	transcriptional regulator
PAM18_RS00880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PAM18_RS00895	COG0835	chemotaxis
PAM18_RS00900	COG0643	Histidine kinase
PAM18_RS00900	COG2198	Histidine kinase
PAM18_RS00905	COG0745	RESPONSE REGULATOR receiver
PAM18_RS00915	COG0583	DNA-binding transcription factor activity
PAM18_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS00930	COG1116	anion transmembrane transporter activity
PAM18_RS00935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS00940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS00980	COG2175	clavaminate synthase activity
PAM18_RS01055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PAM18_RS01085	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS01090	COG1113	amino acid transport
PAM18_RS01105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAM18_RS01110	COG0235	Class ii aldolase
PAM18_RS01115	COG1396	sequence-specific DNA binding
PAM18_RS01120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAM18_RS01125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PAM18_RS01135	COG0477	Major facilitator Superfamily
PAM18_RS01145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PAM18_RS01150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAM18_RS01155	COG0583	DNA-binding transcription factor activity
PAM18_RS01175	COG0673	inositol 2-dehydrogenase activity
PAM18_RS01195	COG2271	Major facilitator Superfamily
PAM18_RS01205	COG1309	transcriptional regulator
PAM18_RS01210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAM18_RS01220	COG0477	Major facilitator Superfamily
PAM18_RS01240	COG2239	Acts as a magnesium transporter
PAM18_RS01335	COG0745	RESPONSE REGULATOR receiver
PAM18_RS01345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAM18_RS01360	COG0583	DNA-binding transcription factor activity
PAM18_RS01365	COG2807	transmembrane transport
PAM18_RS01385	COG0501	Belongs to the peptidase M48B family
PAM18_RS01405	COG4208	sulfate ABC transporter
PAM18_RS01415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PAM18_RS01450	COG2199	diguanylate cyclase activity
PAM18_RS01475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PAM18_RS01480	COG0174	glutamine synthetase
PAM18_RS01485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PAM18_RS01490	COG0174	glutamine synthetase
PAM18_RS01510	COG3842	ATPase activity
PAM18_RS01515	COG1176	ABC-type spermidine putrescine transport system, permease component I
PAM18_RS01520	COG1177	transmembrane transport
PAM18_RS01570	COG0765	amino acid transport
PAM18_RS01585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PAM18_RS01590	COG0277	FAD linked oxidase domain protein
PAM18_RS01595	COG0179	Fumarylacetoacetate (FAA) hydrolase
PAM18_RS01605	COG3111	PFAM Bacterial OB fold (BOF) protein
PAM18_RS01615	COG0531	amino acid
PAM18_RS01625	COG1177	transmembrane transport
PAM18_RS01635	COG3842	ATPase activity
PAM18_RS01640	COG3204	pilus organization
PAM18_RS01645	COG2234	aminopeptidase activity
PAM18_RS01665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PAM18_RS01675	COG0702	epimerase
PAM18_RS01715	COG0730	response to heat
PAM18_RS01750	COG0584	glycerophosphoryl diester phosphodiesterase
PAM18_RS01770	COG0622	Phosphoesterase
PAM18_RS01775	COG2233	PERMEase
PAM18_RS01790	COG0693	protein deglycase activity
PAM18_RS01825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PAM18_RS01835	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PAM18_RS01860	COG0429	hydrolase of the alpha beta-hydrolase fold
PAM18_RS01870	COG0742	ribosomal rna small subunit methyltransferase
PAM18_RS01875	COG0612	Peptidase, M16
PAM18_RS01880	COG0612	Peptidase, M16
PAM18_RS01885	COG0552	protein localization to endoplasmic reticulum
PAM18_RS01890	COG2884	Cell division ATP-binding protein ftsE
PAM18_RS01895	COG2177	Part of the ABC transporter FtsEX involved in
PAM18_RS01915	COG2363	Small membrane protein
PAM18_RS01950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PAM18_RS01965	COG2813	Specifically methylates the guanine in position
PAM18_RS01965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PAM18_RS01975	COG1160	GTP binding
PAM18_RS01980	COG1872	DUF167
PAM18_RS02025	COG0626	cystathionine gamma-synthase activity
PAM18_RS02090	COG0643	Histidine kinase
PAM18_RS02090	COG0784	Response regulator, receiver
PAM18_RS02090	COG2198	Histidine kinase
PAM18_RS02120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PAM18_RS02135	COG3038	cytochrome b561
PAM18_RS02165	COG0513	Belongs to the DEAD box helicase family
PAM18_RS02175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PAM18_RS02180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAM18_RS02205	COG1309	transcriptional regulator
PAM18_RS02210	COG0402	S-adenosylhomocysteine deaminase activity
PAM18_RS02215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PAM18_RS02225	COG0493	'glutamate synthase
PAM18_RS02240	COG1953	Uracil, thiamine, allantoin
PAM18_RS02255	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS02260	COG0583	DNA-binding transcription factor activity
PAM18_RS02270	COG0306	phosphate transporter
PAM18_RS02280	COG0330	HflC and HflK could
PAM18_RS02290	COG1289	transmembrane transporter activity
PAM18_RS02295	COG0513	Belongs to the DEAD box helicase family
PAM18_RS02305	COG4067	protein conserved in archaea
PAM18_RS02305	COG0189	ligase activity
PAM18_RS02315	COG0477	Major facilitator Superfamily
PAM18_RS02320	COG0542	response to heat
PAM18_RS02330	COG0204	Acyl-transferase
PAM18_RS02340	COG0745	RESPONSE REGULATOR receiver
PAM18_RS02345	COG2205	protein histidine kinase activity
PAM18_RS02350	COG4452	Inner membrane protein CreD
PAM18_RS02380	COG4774	siderophore transport
PAM18_RS02385	COG3712	iron ion homeostasis
PAM18_RS02390	COG1595	DNA-templated transcription, initiation
PAM18_RS02395	COG0625	glutathione transferase activity
PAM18_RS02405	COG1309	transcriptional regulator
PAM18_RS02410	COG1953	Uracil, thiamine, allantoin
PAM18_RS02430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PAM18_RS02465	COG2005	Transcriptional regulator
PAM18_RS02465	COG3585	molybdate ion transport
PAM18_RS02470	COG5544	Lipoprotein
PAM18_RS02475	COG1040	competence protein
PAM18_RS02495	COG0511	ligase activity, forming carbon-carbon bonds
PAM18_RS02510	COG1984	allophanate hydrolase subunit 2
PAM18_RS02525	COG3121	Chaperone
PAM18_RS02540	COG2226	methyltransferase
PAM18_RS02540	COG1073	alpha beta
PAM18_RS02560	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS02565	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS02570	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS02580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PAM18_RS02580	COG1648	precorrin-2 dehydrogenase activity
PAM18_RS02670	COG0583	DNA-binding transcription factor activity
PAM18_RS02675	COG2258	MOSC domain
PAM18_RS02685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PAM18_RS02705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS02715	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PAM18_RS02770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PAM18_RS02775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PAM18_RS02785	COG3622	Belongs to the hyi family
PAM18_RS02790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PAM18_RS02830	COG2081	HI0933 family
PAM18_RS02835	COG1451	nucleotide metabolic process
PAM18_RS02840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PAM18_RS02845	COG3152	Membrane
PAM18_RS02850	COG4977	sequence-specific DNA binding
PAM18_RS02850	COG1917	Cupin 2, conserved barrel domain protein
PAM18_RS02855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAM18_RS02950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAM18_RS02970	COG2719	SpoVR family
PAM18_RS02980	COG2766	serine protein kinase
PAM18_RS03030	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PAM18_RS03045	COG2197	response regulator
PAM18_RS03055	COG3842	ATPase activity
PAM18_RS03065	COG1176	ABC-type spermidine putrescine transport system, permease component I
PAM18_RS03075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PAM18_RS03100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PAM18_RS03115	COG3179	chitinase
PAM18_RS03215	COG1765	OsmC-like protein
PAM18_RS03230	COG0537	adenosine 5'-monophosphoramidase activity
PAM18_RS03240	COG0300	oxidoreductase activity
PAM18_RS03255	COG1981	membrane
PAM18_RS03285	COG0739	heme binding
PAM18_RS03450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PAM18_RS03575	COG2814	Major facilitator Superfamily
PAM18_RS03605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
PAM18_RS03630	COG1021	2,3-dihydroxybenzoate-AMP ligase
PAM18_RS03640	COG3433	isochorismatase activity
PAM18_RS03640	COG2226	methyltransferase
PAM18_RS03640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAM18_RS03645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAM18_RS03645	COG3433	isochorismatase activity
PAM18_RS03645	COG2226	methyltransferase
PAM18_RS03655	COG2375	cellular response to nickel ion
PAM18_RS03655	COG1132	(ABC) transporter
PAM18_RS03735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS03740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS03750	COG2706	6-phosphogluconolactonase activity
PAM18_RS03770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAM18_RS03775	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS03785	COG4191	Histidine kinase
PAM18_RS03790	COG4566	intracellular signal transduction
PAM18_RS03795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS03800	COG0765	amino acid transport
PAM18_RS03805	COG0765	amino acid transport
PAM18_RS03830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAM18_RS03835	COG2271	Major facilitator Superfamily
PAM18_RS03880	COG2226	methyltransferase
PAM18_RS03890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAM18_RS03905	COG0251	oxidation-reduction process
PAM18_RS03915	COG0693	protein deglycase activity
PAM18_RS03920	COG0492	ferredoxin-NADP+ reductase activity
PAM18_RS03925	COG1959	2 iron, 2 sulfur cluster binding
PAM18_RS03955	COG0154	amidase activity
PAM18_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS03965	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAM18_RS03970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAM18_RS03975	COG4592	Periplasmic binding protein
PAM18_RS03980	COG1120	ATPase activity
PAM18_RS03990	COG4774	siderophore transport
PAM18_RS03990	COG1629	transport
PAM18_RS03995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAM18_RS04000	COG4991	sh3 domain protein
PAM18_RS04005	COG1063	alcohol dehydrogenase
PAM18_RS04015	COG0022	dehydrogenase e1 component
PAM18_RS04020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PAM18_RS04025	COG3199	ATP-NAD kinase
PAM18_RS04035	COG3284	Transcriptional regulator
PAM18_RS04060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS04090	COG2814	Major facilitator Superfamily
PAM18_RS04095	COG1846	Transcriptional regulator
PAM18_RS04105	COG3278	Belongs to the heme-copper respiratory oxidase family
PAM18_RS04110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAM18_RS04120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAM18_RS04135	COG3971	2-oxopent-4-enoate hydratase activity
PAM18_RS04140	COG2271	Major facilitator Superfamily
PAM18_RS04150	COG3384	dioxygenase
PAM18_RS04155	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS04195	COG1611	Belongs to the LOG family
PAM18_RS04255	COG2259	Doxx family
PAM18_RS04265	COG2205	protein histidine kinase activity
PAM18_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS04295	COG1063	alcohol dehydrogenase
PAM18_RS04300	COG2271	Major facilitator Superfamily
PAM18_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS04340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PAM18_RS04355	COG3121	Chaperone
PAM18_RS04360	COG3188	usher protein
PAM18_RS04380	COG2197	response regulator
PAM18_RS04420	COG0531	amino acid
PAM18_RS04440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAM18_RS04450	COG3047	cAMP biosynthetic process
PAM18_RS04480	COG3118	belongs to the thioredoxin family
PAM18_RS04485	COG2264	protein methyltransferase activity
PAM18_RS04500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAM18_RS04500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAM18_RS04525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PAM18_RS04530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PAM18_RS04540	COG3577	Aspartyl protease
PAM18_RS04565	COG0142	geranyltranstransferase activity
PAM18_RS04575	COG4948	Mandelate Racemase Muconate Lactonizing
PAM18_RS04595	COG1131	(ABC) transporter
PAM18_RS04600	COG5002	protein histidine kinase activity
PAM18_RS04620	COG0745	RESPONSE REGULATOR receiver
PAM18_RS04630	COG3228	Belongs to the MtfA family
PAM18_RS04635	COG0586	Pfam SNARE associated Golgi protein
PAM18_RS04650	COG0456	acetyltransferase
PAM18_RS04660	COG4303	Ethanolamine ammonia lyase large subunit
PAM18_RS04665	COG0531	amino acid
PAM18_RS04675	COG3284	Transcriptional regulator
PAM18_RS04680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PAM18_RS04695	COG0702	epimerase
PAM18_RS04715	COG1346	cytolysis
PAM18_RS04725	COG0586	Pfam SNARE associated Golgi protein
PAM18_RS04765	COG0768	penicillin binding
PAM18_RS04770	COG0772	Belongs to the SEDS family
PAM18_RS04775	COG2951	lytic endotransglycosylase activity
PAM18_RS04785	COG1686	Belongs to the peptidase S11 family
PAM18_RS04815	COG2951	lytic endotransglycosylase activity
PAM18_RS04850	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PAM18_RS04860	COG4535	Mg2 and Co2 transporter CorC
PAM18_RS04870	COG1702	phosphate starvation-inducible protein PhoH
PAM18_RS04900	COG0351	phosphomethylpyrimidine kinase
PAM18_RS04905	COG2198	Histidine kinase
PAM18_RS04905	COG0784	Response regulator, receiver
PAM18_RS04905	COG2205	protein histidine kinase activity
PAM18_RS04915	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS04925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PAM18_RS04965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAM18_RS04975	COG1643	Atp-dependent helicase
PAM18_RS05020	COG3416	Protein conserved in bacteria
PAM18_RS05030	COG0513	Belongs to the DEAD box helicase family
PAM18_RS05040	COG2197	response regulator
PAM18_RS05045	COG2200	EAL domain
PAM18_RS05045	COG2202	Pas domain
PAM18_RS05045	COG2199	diguanylate cyclase activity
PAM18_RS05050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS05050	COG2205	protein histidine kinase activity
PAM18_RS05070	COG1946	Acyl-CoA thioesterase
PAM18_RS05090	COG4521	taurine ABC transporter
PAM18_RS05100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS05105	COG2175	clavaminate synthase activity
PAM18_RS05110	COG1297	OPT oligopeptide transporter protein
PAM18_RS05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PAM18_RS05130	COG1271	oxidase subunit
PAM18_RS05135	COG1294	oxidase, subunit
PAM18_RS05145	COG2207	Transcriptional regulator
PAM18_RS05155	COG0183	Belongs to the thiolase family
PAM18_RS05160	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS05185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PAM18_RS05195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PAM18_RS05205	COG0521	Mo-molybdopterin cofactor biosynthetic process
PAM18_RS05210	COG0303	'Molybdopterin
PAM18_RS05215	COG0826	peptidase U32
PAM18_RS05220	COG0826	peptidase U32
PAM18_RS05225	COG3154	lipid carrier protein
PAM18_RS05275	COG4772	TonB-dependent receptor
PAM18_RS05280	COG3712	iron ion homeostasis
PAM18_RS05285	COG1595	DNA-templated transcription, initiation
PAM18_RS05295	COG0697	spore germination
PAM18_RS05305	COG0583	DNA-binding transcription factor activity
PAM18_RS05325	COG1566	PFAM secretion protein HlyD family protein
PAM18_RS05375	COG0300	oxidoreductase activity
PAM18_RS05380	COG2226	methyltransferase
PAM18_RS05395	COG2197	response regulator
PAM18_RS05400	COG3850	Histidine kinase
PAM18_RS05410	COG2223	nitrite transmembrane transporter activity
PAM18_RS05415	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAM18_RS05420	COG1140	nitrate reductase beta subunit
PAM18_RS05425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PAM18_RS05430	COG2181	nitrate reductase activity
PAM18_RS05435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAM18_RS05445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS05470	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS05480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS05545	COG0583	DNA-binding transcription factor activity
PAM18_RS05575	COG0471	metal ion transport
PAM18_RS05575	COG0490	domain, Protein
PAM18_RS05580	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PAM18_RS05585	COG4120	Belongs to the binding-protein-dependent transport system permease family
PAM18_RS05630	COG0795	lipopolysaccharide-transporting ATPase activity
PAM18_RS05635	COG0795	lipopolysaccharide-transporting ATPase activity
PAM18_RS05645	COG2200	EAL domain
PAM18_RS05665	COG1862	Preprotein translocase
PAM18_RS05680	COG3134	Outer membrane lipoprotein
PAM18_RS05695	COG1045	serine acetyltransferase
PAM18_RS05785	COG0436	Aminotransferase
PAM18_RS05790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PAM18_RS05800	COG0667	Aldo Keto reductase
PAM18_RS05840	COG0739	heme binding
PAM18_RS05850	COG2847	Copper chaperone PCu(A)C
PAM18_RS05860	COG1335	isochorismatase
PAM18_RS05875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PAM18_RS05885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PAM18_RS05890	COG0583	DNA-binding transcription factor activity
PAM18_RS05960	COG2130	NADP-dependent
PAM18_RS05965	COG2132	Multicopper oxidase
PAM18_RS05970	COG0590	tRNA wobble adenosine to inosine editing
PAM18_RS06005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAM18_RS06005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PAM18_RS06010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PAM18_RS06015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PAM18_RS06020	COG2188	Transcriptional regulator
PAM18_RS06060	COG0477	Major facilitator Superfamily
PAM18_RS06065	COG4536	flavin adenine dinucleotide binding
PAM18_RS06075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PAM18_RS06100	COG1607	acyl-coa hydrolase
PAM18_RS06120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PAM18_RS06145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PAM18_RS06170	COG2255	four-way junction helicase activity
PAM18_RS06185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PAM18_RS06195	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS06240	COG2197	response regulator
PAM18_RS06245	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PAM18_RS06265	COG0477	Major facilitator Superfamily
PAM18_RS06300	COG5001	Diguanylate cyclase
PAM18_RS06300	COG3706	GGDEF domain
PAM18_RS06300	COG2203	Gaf domain
PAM18_RS06300	COG4251	negative regulation of phosphorylation
PAM18_RS06305	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PAM18_RS06335	COG3064	Membrane
PAM18_RS06335	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PAM18_RS06335	COG1073	alpha beta
PAM18_RS06350	COG2885	chlorophyll binding
PAM18_RS06365	COG0789	Transcriptional regulator
PAM18_RS06385	COG1214	PFAM Peptidase M22, glycoprotease
PAM18_RS06395	COG1801	Protein of unknown function DUF72
PAM18_RS06400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PAM18_RS06425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS06470	COG2166	iron-sulfur cluster assembly
PAM18_RS06490	COG1393	Belongs to the ArsC family
PAM18_RS06510	COG0025	NhaP-type Na H and K H
PAM18_RS06515	COG0436	Aminotransferase
PAM18_RS06525	COG0024	Methionine aminopeptidase
PAM18_RS06570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PAM18_RS06605	COG1115	amino acid carrier protein
PAM18_RS06655	COG2391	methyltransferase activity
PAM18_RS06660	COG0583	DNA-binding transcription factor activity
PAM18_RS06665	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PAM18_RS06670	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PAM18_RS06795	COG1475	DNA binding
PAM18_RS06850	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
PAM18_RS06865	COG1598	PFAM Uncharacterised protein family UPF0150
PAM18_RS06870	COG1724	mRNA binding
PAM18_RS06880	COG3179	chitinase
PAM18_RS06900	COG1802	Transcriptional regulator
PAM18_RS06900	COG4626	Terminase
PAM18_RS06905	COG4695	Portal protein
PAM18_RS07040	COG1546	Belongs to the CinA family
PAM18_RS07060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PAM18_RS07065	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PAM18_RS07070	COG3530	Putative quorum-sensing-regulated virulence factor
PAM18_RS07085	COG1177	transmembrane transport
PAM18_RS07090	COG1176	ABC-type spermidine putrescine transport system, permease component I
PAM18_RS07100	COG3148	PFAM DTW domain containing protein
PAM18_RS07120	COG0069	glutamate synthase activity
PAM18_RS07145	COG0531	amino acid
PAM18_RS07150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAM18_RS07150	COG2169	Transcriptional regulator
PAM18_RS07155	COG0477	Major facilitator Superfamily
PAM18_RS07160	COG0583	DNA-binding transcription factor activity
PAM18_RS07165	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS07170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PAM18_RS07175	COG1024	Enoyl-CoA hydratase
PAM18_RS07180	COG1250	3-hydroxyacyl-CoA dehydrogenase
PAM18_RS07185	COG0183	Belongs to the thiolase family
PAM18_RS07195	COG0583	DNA-binding transcription factor activity
PAM18_RS07230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAM18_RS07275	COG2814	Major facilitator Superfamily
PAM18_RS07315	COG0583	DNA-binding transcription factor activity
PAM18_RS07325	COG0084	hydrolase, TatD family'
PAM18_RS07330	COG1609	Transcriptional regulator
PAM18_RS07340	COG1105	Belongs to the carbohydrate kinase PfkB family
PAM18_RS07345	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PAM18_RS07345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PAM18_RS07345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PAM18_RS07455	COG3842	ATPase activity
PAM18_RS07475	COG0243	molybdopterin cofactor binding
PAM18_RS07480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PAM18_RS07485	COG2223	nitrite transmembrane transporter activity
PAM18_RS07500	COG0450	alkyl hydroperoxide reductase
PAM18_RS07530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS07565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PAM18_RS07570	COG2264	protein methyltransferase activity
PAM18_RS07580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PAM18_RS07635	COG0489	protein tyrosine kinase activity
PAM18_RS07680	COG0791	NLP P60 protein
PAM18_RS07695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAM18_RS07700	COG0668	transmembrane transport
PAM18_RS07705	COG0477	Major facilitator Superfamily
PAM18_RS07710	COG0513	Belongs to the DEAD box helicase family
PAM18_RS07730	COG0784	Response regulator, receiver
PAM18_RS07730	COG2205	protein histidine kinase activity
PAM18_RS07730	COG5002	protein histidine kinase activity
PAM18_RS07735	COG1363	Peptidase, m42
PAM18_RS07740	COG0189	ligase activity
PAM18_RS07740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PAM18_RS07745	COG0367	asparagine synthase
PAM18_RS07770	COG0183	Belongs to the thiolase family
PAM18_RS07790	COG0450	alkyl hydroperoxide reductase
PAM18_RS07795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS07800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS07810	COG0431	NADPH-dependent FMN reductase
PAM18_RS07815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS07825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS07850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAM18_RS07875	COG0583	DNA-binding transcription factor activity
PAM18_RS07880	COG1380	Effector of murein hydrolase LrgA
PAM18_RS07885	COG1346	cytolysis
PAM18_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS07910	COG1024	Enoyl-CoA hydratase
PAM18_RS07920	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PAM18_RS07965	COG0508	dehydrogenase complex catalyzes the overall conversion of
PAM18_RS08005	COG1629	transport
PAM18_RS08060	COG0583	DNA-binding transcription factor activity
PAM18_RS08135	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PAM18_RS08140	COG3639	organic phosphonate transmembrane transporter activity
PAM18_RS08145	COG2188	Transcriptional regulator
PAM18_RS08150	COG3624	Phosphonate C-P lyase system protein PhnG
PAM18_RS08160	COG3626	phosphonate metabolism
PAM18_RS08165	COG3627	carbon phosphorus lyase activity
PAM18_RS08170	COG4107	phosphonate C-P lyase system protein PhnK
PAM18_RS08175	COG4778	phosphonate C-P lyase system protein PhnL
PAM18_RS08180	COG3454	Phosphonate metabolism
PAM18_RS08190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PAM18_RS08260	COG0697	spore germination
PAM18_RS08285	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PAM18_RS08305	COG0784	Response regulator, receiver
PAM18_RS08305	COG0835	chemotaxis
PAM18_RS08320	COG0745	RESPONSE REGULATOR receiver
PAM18_RS08330	COG0514	ATP-dependent DNA helicase (RecQ)
PAM18_RS08335	COG4251	negative regulation of phosphorylation
PAM18_RS08335	COG3706	GGDEF domain
PAM18_RS08335	COG5001	Diguanylate cyclase
PAM18_RS08335	COG2203	Gaf domain
PAM18_RS08355	COG1752	Esterase of the alpha-beta hydrolase superfamily
PAM18_RS08395	COG2124	cytochrome p450
PAM18_RS08400	COG4221	oxidoreductase activity
PAM18_RS08445	COG0583	DNA-binding transcription factor activity
PAM18_RS08475	COG3639	organic phosphonate transmembrane transporter activity
PAM18_RS08485	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PAM18_RS08490	COG2084	Dehydrogenase
PAM18_RS08505	COG0589	response to stress
PAM18_RS08545	COG2814	Major facilitator Superfamily
PAM18_RS08550	COG2030	dehydratase
PAM18_RS08555	COG2267	carboxylic ester hydrolase activity
PAM18_RS08560	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS08565	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS08575	COG1643	Atp-dependent helicase
PAM18_RS08585	COG0537	adenosine 5'-monophosphoramidase activity
PAM18_RS08630	COG1595	DNA-templated transcription, initiation
PAM18_RS08700	COG1201	RNA secondary structure unwinding
PAM18_RS08705	COG0784	Response regulator, receiver
PAM18_RS08705	COG2205	protein histidine kinase activity
PAM18_RS08720	COG4772	TonB-dependent receptor
PAM18_RS08735	COG2076	Multidrug Resistance protein
PAM18_RS08740	COG0385	Bile acid
PAM18_RS08800	COG0604	alcohol dehydrogenase
PAM18_RS08800	COG3321	synthase
PAM18_RS08805	COG0560	Phosphoserine phosphatase
PAM18_RS08820	COG1176	ABC-type spermidine putrescine transport system, permease component I
PAM18_RS08850	COG0564	pseudouridine synthase activity
PAM18_RS08860	COG2894	cell division
PAM18_RS08870	COG1560	Kdo2-lipid A biosynthetic process
PAM18_RS08885	COG2853	Lipoprotein
PAM18_RS08905	COG3162	membrane
PAM18_RS08910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAM18_RS08940	COG1132	(ABC) transporter
PAM18_RS08950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PAM18_RS08975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAM18_RS08990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PAM18_RS08990	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS09020	COG1127	ABC transporter
PAM18_RS09025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PAM18_RS09030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PAM18_RS09035	COG0727	PFAM Uncharacterised protein family (UPF0153)
PAM18_RS09040	COG0778	Nitroreductase
PAM18_RS09060	COG0745	RESPONSE REGULATOR receiver
PAM18_RS09070	COG2350	Protein conserved in bacteria
PAM18_RS09080	COG0613	PHP domain protein
PAM18_RS09085	COG0009	L-threonylcarbamoyladenylate synthase
PAM18_RS09095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PAM18_RS09140	COG1175	transmembrane transport
PAM18_RS09145	COG0395	ABC-type sugar transport system, permease component
PAM18_RS09150	COG3842	ATPase activity
PAM18_RS09160	COG0676	glucose-6-phosphate 1-epimerase activity
PAM18_RS09205	COG0786	glutamate:sodium symporter activity
PAM18_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS09235	COG0402	S-adenosylhomocysteine deaminase activity
PAM18_RS09265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PAM18_RS09310	COG0367	asparagine synthase
PAM18_RS09315	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS09320	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS09330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PAM18_RS09370	COG0583	DNA-binding transcription factor activity
PAM18_RS09405	COG0596	Alpha beta hydrolase
PAM18_RS09410	COG0800	Aldolase
PAM18_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS09445	COG0583	DNA-binding transcription factor activity
PAM18_RS09450	COG0251	oxidation-reduction process
PAM18_RS09470	COG2226	methyltransferase
PAM18_RS09510	COG0285	dihydrofolate synthase activity
PAM18_RS09515	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PAM18_RS09520	COG1286	toxin biosynthetic process
PAM18_RS09620	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS09620	COG0446	pyridine nucleotide-disulphide oxidoreductase
PAM18_RS09645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PAM18_RS09655	COG3139	Protein of unknown function (DUF1315)
PAM18_RS09665	COG0308	aminopeptidase N
PAM18_RS09695	COG0745	RESPONSE REGULATOR receiver
PAM18_RS09730	COG0714	Associated with various cellular activities
PAM18_RS09745	COG2342	PFAM TM1410 hypothetical-related protein
PAM18_RS09770	COG0297	glycogen (starch) synthase activity
PAM18_RS09820	COG3130	regulation of translation
PAM18_RS09830	COG2027	D-alanyl-D-alanine carboxypeptidase
PAM18_RS09835	COG3171	Protein conserved in bacteria
PAM18_RS09840	COG2197	response regulator
PAM18_RS09845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS09845	COG2205	protein histidine kinase activity
PAM18_RS09870	COG0004	ammonium transporteR
PAM18_RS09880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAM18_RS09890	COG0625	glutathione transferase activity
PAM18_RS09895	COG1309	transcriptional regulator
PAM18_RS09925	COG0521	Mo-molybdopterin cofactor biosynthetic process
PAM18_RS09945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PAM18_RS09950	COG1070	Carbohydrate kinase
PAM18_RS09970	COG0741	lytic transglycosylase activity
PAM18_RS09975	COG0488	(ABC) transporter
PAM18_RS09985	COG0589	response to stress
PAM18_RS10060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PAM18_RS10070	COG1113	amino acid transport
PAM18_RS10105	COG1477	protein flavinylation
PAM18_RS10120	COG0584	glycerophosphoryl diester phosphodiesterase
PAM18_RS10135	COG4591	ABC-type transport system involved in lipoprotein release permease component
PAM18_RS10155	COG0658	competence protein
PAM18_RS10155	COG2333	competence protein COMEC
PAM18_RS10160	COG0811	peptide transport
PAM18_RS10165	COG0848	biopolymer transport protein
PAM18_RS10185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAM18_RS10195	COG1530	ribonuclease E activity
PAM18_RS10210	COG0616	signal peptide processing
PAM18_RS10210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PAM18_RS10220	COG1399	metal-binding, possibly nucleic acid-binding protein
PAM18_RS10250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PAM18_RS10260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAM18_RS10280	COG0084	hydrolase, TatD family'
PAM18_RS10365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PAM18_RS10380	COG0183	Belongs to the thiolase family
PAM18_RS10390	COG2233	PERMEase
PAM18_RS10400	COG3038	cytochrome b561
PAM18_RS10415	COG2814	Major facilitator Superfamily
PAM18_RS10420	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS10425	COG1309	transcriptional regulator
PAM18_RS10455	COG4160	amino acid transport
PAM18_RS10460	COG4215	(ABC) transporter
PAM18_RS10465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS10470	COG1473	amidohydrolase
PAM18_RS10475	COG0583	DNA-binding transcription factor activity
PAM18_RS10510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAM18_RS10520	COG1120	ATPase activity
PAM18_RS10550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAM18_RS10580	COG2885	chlorophyll binding
PAM18_RS10580	COG3047	cAMP biosynthetic process
PAM18_RS10585	COG2197	response regulator
PAM18_RS10595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAM18_RS10600	COG1595	DNA-templated transcription, initiation
PAM18_RS10620	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS10635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PAM18_RS10640	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS10645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PAM18_RS10660	COG1309	transcriptional regulator
PAM18_RS10690	COG0583	DNA-binding transcription factor activity
PAM18_RS10700	COG0583	DNA-binding transcription factor activity
PAM18_RS10710	COG0714	Associated with various cellular activities
PAM18_RS10755	COG0084	hydrolase, TatD family'
PAM18_RS10760	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PAM18_RS10765	COG2259	Doxx family
PAM18_RS10780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PAM18_RS10795	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PAM18_RS10800	COG4181	ATPase activity
PAM18_RS10840	COG1764	response to oxidative stress
PAM18_RS10845	COG1846	Transcriptional regulator
PAM18_RS10850	COG0583	DNA-binding transcription factor activity
PAM18_RS10860	COG0583	DNA-binding transcription factor activity
PAM18_RS10870	COG3214	Protein conserved in bacteria
PAM18_RS10875	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PAM18_RS10885	COG1024	Enoyl-CoA hydratase
PAM18_RS10895	COG3384	dioxygenase
PAM18_RS10935	COG2866	Carboxypeptidase
PAM18_RS10950	COG0436	Aminotransferase
PAM18_RS10960	COG0386	Belongs to the glutathione peroxidase family
PAM18_RS10965	COG1846	Transcriptional regulator
PAM18_RS10970	COG2205	protein histidine kinase activity
PAM18_RS10970	COG0784	Response regulator, receiver
PAM18_RS10970	COG5002	protein histidine kinase activity
PAM18_RS10975	COG2255	four-way junction helicase activity
PAM18_RS10980	COG1956	GAF domain-containing protein
PAM18_RS10985	COG0625	glutathione transferase activity
PAM18_RS11010	COG2200	EAL domain
PAM18_RS11035	COG0625	glutathione transferase activity
PAM18_RS11040	COG1131	(ABC) transporter
PAM18_RS11045	COG0842	Transport permease protein
PAM18_RS11090	COG2188	Transcriptional regulator
PAM18_RS11100	COG2853	Lipoprotein
PAM18_RS11110	COG0745	RESPONSE REGULATOR receiver
PAM18_RS11130	COG1335	isochorismatase
PAM18_RS11185	COG3655	Transcriptional regulator
PAM18_RS11225	COG2116	formate transmembrane transporter activity
PAM18_RS11230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS11285	COG1051	belongs to the nudix hydrolase family
PAM18_RS11295	COG1024	Enoyl-CoA hydratase
PAM18_RS11295	COG1250	3-hydroxyacyl-CoA dehydrogenase
PAM18_RS11305	COG2837	iron assimilation
PAM18_RS11390	COG1238	metal cluster binding
PAM18_RS11400	COG1295	ribonuclease BN
PAM18_RS11430	COG0024	Methionine aminopeptidase
PAM18_RS11505	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PAM18_RS11510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PAM18_RS11545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PAM18_RS11545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PAM18_RS11555	COG0542	response to heat
PAM18_RS11590	COG0789	Transcriptional regulator
PAM18_RS11600	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS11600	COG0446	pyridine nucleotide-disulphide oxidoreductase
PAM18_RS11605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PAM18_RS11610	COG0243	molybdopterin cofactor binding
PAM18_RS11630	COG1280	lysine exporter protein (LysE YggA)
PAM18_RS11645	COG0542	response to heat
PAM18_RS11715	COG1607	acyl-coa hydrolase
PAM18_RS11720	COG1959	2 iron, 2 sulfur cluster binding
PAM18_RS11735	COG2819	hydrolase of the alpha beta superfamily
PAM18_RS11780	COG0583	DNA-binding transcription factor activity
PAM18_RS11790	COG4106	trans-aconitate 2-methyltransferase activity
PAM18_RS11800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PAM18_RS11805	COG1459	type II secretion system
PAM18_RS11815	COG2165	general secretion pathway protein
PAM18_RS11855	COG0720	synthase
PAM18_RS11860	COG3604	Transcriptional regulator
PAM18_RS11920	COG0840	transmembrane signaling receptor activity
PAM18_RS11925	COG2056	Na+-H+ antiporter family
PAM18_RS11945	COG2226	methyltransferase
PAM18_RS12040	COG2153	protein acetylation
PAM18_RS12045	COG2850	peptidyl-arginine hydroxylation
PAM18_RS12085	COG1278	Cold shock
PAM18_RS12095	COG0542	response to heat
PAM18_RS12100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PAM18_RS12115	COG0492	ferredoxin-NADP+ reductase activity
PAM18_RS12130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PAM18_RS12145	COG0435	Glutathione S-transferase
PAM18_RS12150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PAM18_RS12155	COG2920	part of a sulfur-relay system
PAM18_RS12195	COG0583	DNA-binding transcription factor activity
PAM18_RS12200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAM18_RS12205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS12215	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS12220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS12230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS12235	COG3424	synthase
PAM18_RS12275	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS12280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAM18_RS12290	COG1309	transcriptional regulator
PAM18_RS12300	COG1131	(ABC) transporter
PAM18_RS12305	COG0842	Transport permease protein
PAM18_RS12310	COG0842	Transport permease protein
PAM18_RS12335	COG2197	response regulator
PAM18_RS12340	COG4771	TonB-dependent receptor
PAM18_RS12380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS12380	COG0784	Response regulator, receiver
PAM18_RS12380	COG2205	protein histidine kinase activity
PAM18_RS12380	COG2198	Histidine kinase
PAM18_RS12400	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAM18_RS12415	COG1522	sequence-specific DNA binding
PAM18_RS12445	COG4191	Histidine kinase
PAM18_RS12500	COG3723	Recombinational DNA repair protein, rece pathway
PAM18_RS12530	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PAM18_RS12575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PAM18_RS12590	COG1598	PFAM Uncharacterised protein family UPF0150
PAM18_RS12600	COG3179	chitinase
PAM18_RS12615	COG4220	transposase activity
PAM18_RS12710	COG1278	Cold shock
PAM18_RS12730	COG4251	negative regulation of phosphorylation
PAM18_RS12730	COG2203	Gaf domain
PAM18_RS12730	COG5001	Diguanylate cyclase
PAM18_RS12730	COG3706	GGDEF domain
PAM18_RS12755	COG0659	secondary active sulfate transmembrane transporter activity
PAM18_RS12790	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS12800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PAM18_RS12810	COG0183	Belongs to the thiolase family
PAM18_RS12815	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS12865	COG0729	surface antigen
PAM18_RS12875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAM18_RS12880	COG2267	carboxylic ester hydrolase activity
PAM18_RS12885	COG0671	phosphoesterase, PA-phosphatase related
PAM18_RS12885	COG2453	phosphatase
PAM18_RS12900	COG4589	Belongs to the CDS family
PAM18_RS12905	COG0667	Aldo Keto reductase
PAM18_RS12915	COG1115	amino acid carrier protein
PAM18_RS12925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PAM18_RS12945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS12950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS12955	COG1538	Outer membrane efflux protein
PAM18_RS13015	COG0543	2 iron, 2 sulfur cluster binding
PAM18_RS13015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAM18_RS13020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PAM18_RS13025	COG4638	Rieske (2fe-2S)
PAM18_RS13040	COG4948	Mandelate Racemase Muconate Lactonizing
PAM18_RS13050	COG3485	protocatechuate 3,4-dioxygenase
PAM18_RS13085	COG2807	transmembrane transport
PAM18_RS13090	COG0590	tRNA wobble adenosine to inosine editing
PAM18_RS13105	COG2318	DinB family
PAM18_RS13165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAM18_RS13170	COG2863	cytochrome
PAM18_RS13175	COG3258	Cytochrome c
PAM18_RS13180	COG0642	Histidine kinase
PAM18_RS13215	COG0625	glutathione transferase activity
PAM18_RS13235	COG0583	DNA-binding transcription factor activity
PAM18_RS13240	COG1595	DNA-templated transcription, initiation
PAM18_RS13245	COG3712	iron ion homeostasis
PAM18_RS13285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PAM18_RS13295	COG2382	esterase
PAM18_RS13315	COG0583	DNA-binding transcription factor activity
PAM18_RS13335	COG1760	l-serine dehydratase
PAM18_RS13340	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PAM18_RS13375	COG2217	Heavy metal translocating P-type atpase
PAM18_RS13390	COG0583	DNA-binding transcription factor activity
PAM18_RS13405	COG1566	PFAM secretion protein HlyD family protein
PAM18_RS13495	COG1335	isochorismatase
PAM18_RS13505	COG0583	DNA-binding transcription factor activity
PAM18_RS13545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PAM18_RS13550	COG1121	(ABC) transporter
PAM18_RS13590	COG0657	acetylesterase activity
PAM18_RS13595	COG4774	siderophore transport
PAM18_RS13640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS13665	COG0735	belongs to the Fur family
PAM18_RS13675	COG1304	FMN binding
PAM18_RS13705	COG4566	intracellular signal transduction
PAM18_RS13795	COG3829	transcription factor binding
PAM18_RS13820	COG3829	transcription factor binding
PAM18_RS13825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PAM18_RS13830	COG0584	glycerophosphoryl diester phosphodiesterase
PAM18_RS13835	COG2011	ABC-type metal ion transport system permease component
PAM18_RS13845	COG1464	Belongs to the NlpA lipoprotein family
PAM18_RS13870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAM18_RS13875	COG1070	Carbohydrate kinase
PAM18_RS13880	COG0246	Mannitol dehydrogenase
PAM18_RS13895	COG1175	transmembrane transport
PAM18_RS13915	COG4771	TonB-dependent receptor
PAM18_RS13930	COG1917	Cupin 2, conserved barrel domain protein
PAM18_RS13930	COG4977	sequence-specific DNA binding
PAM18_RS13945	COG1116	anion transmembrane transporter activity
PAM18_RS13950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PAM18_RS13955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS13975	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS13985	COG3265	gluconokinase activity
PAM18_RS13990	COG1609	Transcriptional regulator
PAM18_RS14000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS14005	COG0583	DNA-binding transcription factor activity
PAM18_RS14025	COG1396	sequence-specific DNA binding
PAM18_RS14035	COG2175	clavaminate synthase activity
PAM18_RS14045	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PAM18_RS14050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS14075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAM18_RS14075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PAM18_RS14085	COG3469	chitinase activity
PAM18_RS14090	COG2188	Transcriptional regulator
PAM18_RS14095	COG1053	succinate dehydrogenase
PAM18_RS14110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PAM18_RS14140	COG4772	TonB-dependent receptor
PAM18_RS14185	COG0431	NADPH-dependent FMN reductase
PAM18_RS14190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAM18_RS14200	COG0640	Transcriptional regulator
PAM18_RS14205	COG2207	Transcriptional regulator
PAM18_RS14210	COG1064	alcohol dehydrogenase
PAM18_RS14235	COG1309	transcriptional regulator
PAM18_RS14245	COG2329	Antibiotic biosynthesis monooxygenase
PAM18_RS14280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAM18_RS14290	COG1609	Transcriptional regulator
PAM18_RS14320	COG0252	asparaginase activity
PAM18_RS14325	COG1115	amino acid carrier protein
PAM18_RS14370	COG1053	succinate dehydrogenase
PAM18_RS14380	COG0728	peptidoglycan biosynthetic process
PAM18_RS14440	COG2258	MOSC domain
PAM18_RS14475	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS14485	COG4948	Mandelate Racemase Muconate Lactonizing
PAM18_RS14490	COG2271	Major facilitator Superfamily
PAM18_RS14505	COG3618	amidohydrolase
PAM18_RS14510	COG2271	Major facilitator Superfamily
PAM18_RS14545	COG0765	amino acid transport
PAM18_RS14550	COG0765	amino acid transport
PAM18_RS14565	COG2084	Dehydrogenase
PAM18_RS14575	COG2130	NADP-dependent
PAM18_RS14580	COG1309	transcriptional regulator
PAM18_RS14600	COG0366	Alpha amylase catalytic
PAM18_RS14605	COG0517	IMP dehydrogenase activity
PAM18_RS14630	COG1063	alcohol dehydrogenase
PAM18_RS14645	COG3546	catalase activity
PAM18_RS14650	COG3685	Protein conserved in bacteria
PAM18_RS14675	COG2890	protein-(glutamine-N5) methyltransferase activity
PAM18_RS14690	COG0784	Response regulator, receiver
PAM18_RS14690	COG4191	Histidine kinase
PAM18_RS14720	COG1363	Peptidase, m42
PAM18_RS14760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PAM18_RS14800	COG3568	Endonuclease Exonuclease Phosphatase
PAM18_RS14805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAM18_RS14810	COG0392	lysyltransferase activity
PAM18_RS14820	COG0366	Alpha amylase catalytic
PAM18_RS14840	COG1285	pathogenesis
PAM18_RS14860	COG0058	SHG alpha-glucan phosphorylase activity
PAM18_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS14880	COG1546	Belongs to the CinA family
PAM18_RS14910	COG2323	membrane
PAM18_RS14930	COG3121	Chaperone
PAM18_RS14940	COG3188	usher protein
PAM18_RS14945	COG3121	Chaperone
PAM18_RS14955	COG3969	phosphoadenosine phosphosulfate
PAM18_RS14965	COG1475	DNA binding
PAM18_RS14970	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS14975	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PAM18_RS14980	COG0583	DNA-binding transcription factor activity
PAM18_RS15000	COG1063	alcohol dehydrogenase
PAM18_RS15010	COG2169	Transcriptional regulator
PAM18_RS15010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAM18_RS15025	COG0583	DNA-binding transcription factor activity
PAM18_RS15030	COG2814	Major facilitator Superfamily
PAM18_RS15050	COG1984	allophanate hydrolase subunit 2
PAM18_RS15060	COG0028	Belongs to the TPP enzyme family
PAM18_RS15070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PAM18_RS15075	COG1045	serine acetyltransferase
PAM18_RS15080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PAM18_RS15100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAM18_RS15105	COG0300	oxidoreductase activity
PAM18_RS15140	COG2814	Major facilitator Superfamily
PAM18_RS15150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAM18_RS15170	COG0596	Alpha beta hydrolase
PAM18_RS15175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PAM18_RS15180	COG0367	asparagine synthase
PAM18_RS15190	COG1522	sequence-specific DNA binding
PAM18_RS15205	COG1113	amino acid transport
PAM18_RS15210	COG2010	Cytochrome c
PAM18_RS15215	COG2010	Cytochrome c
PAM18_RS15235	COG3153	acetyltransferase
PAM18_RS15235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PAM18_RS15240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PAM18_RS15245	COG5001	Diguanylate cyclase
PAM18_RS15255	COG4206	TonB-dependent receptor
PAM18_RS15260	COG2192	nodulation
PAM18_RS15265	COG2814	Major facilitator Superfamily
PAM18_RS15295	COG1104	cysteine desulfurase activity
PAM18_RS15300	COG4172	Belongs to the ABC transporter superfamily
PAM18_RS15305	COG4239	(ABC) transporter, permease
PAM18_RS15310	COG4174	ABC transporter (Permease)
PAM18_RS15320	COG4206	TonB-dependent receptor
PAM18_RS15335	COG0583	DNA-binding transcription factor activity
PAM18_RS15355	COG1595	DNA-templated transcription, initiation
PAM18_RS15370	COG2207	Transcriptional regulator
PAM18_RS15390	COG0564	pseudouridine synthase activity
PAM18_RS15400	COG0531	amino acid
PAM18_RS15405	COG0174	glutamine synthetase
PAM18_RS15430	COG0028	Belongs to the TPP enzyme family
PAM18_RS15445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAM18_RS15465	COG1522	sequence-specific DNA binding
PAM18_RS15505	COG1309	transcriptional regulator
PAM18_RS15510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS15515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS15525	COG3204	pilus organization
PAM18_RS15530	COG0789	Transcriptional regulator
PAM18_RS15535	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS15540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PAM18_RS15570	COG0179	Fumarylacetoacetate (FAA) hydrolase
PAM18_RS15580	COG2271	Major facilitator Superfamily
PAM18_RS15585	COG3829	transcription factor binding
PAM18_RS15585	COG3290	protein histidine kinase activity
PAM18_RS15590	COG2610	gluconate transmembrane transporter activity
PAM18_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS15600	COG2031	fatty acid transporter
PAM18_RS15615	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAM18_RS15620	COG0583	DNA-binding transcription factor activity
PAM18_RS15625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PAM18_RS15630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAM18_RS15650	COG2205	protein histidine kinase activity
PAM18_RS15715	COG3851	Histidine kinase
PAM18_RS15730	COG2205	protein histidine kinase activity
PAM18_RS15730	COG0784	Response regulator, receiver
PAM18_RS15750	COG2194	sulfuric ester hydrolase activity
PAM18_RS15795	COG0488	(ABC) transporter
PAM18_RS15810	COG0583	DNA-binding transcription factor activity
PAM18_RS15815	COG1278	Cold shock
PAM18_RS15865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAM18_RS15870	COG1609	Transcriptional regulator
PAM18_RS15875	COG1172	Belongs to the binding-protein-dependent transport system permease family
PAM18_RS15880	COG1129	ABC transporter
PAM18_RS15890	COG2204	response regulator
PAM18_RS15905	COG2010	Cytochrome c
PAM18_RS15910	COG0753	catalase activity
PAM18_RS15925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PAM18_RS15930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PAM18_RS15935	COG2080	2 iron, 2 sulfur cluster binding
PAM18_RS15960	COG1944	ATP diphosphatase activity
PAM18_RS15980	COG4771	TonB-dependent receptor
PAM18_RS15985	COG0275	rRNA processing
PAM18_RS15990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAM18_RS15990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PAM18_RS16005	COG0579	oxidoreductase
PAM18_RS16035	COG1595	DNA-templated transcription, initiation
PAM18_RS16040	COG3712	iron ion homeostasis
PAM18_RS16060	COG2814	Major facilitator Superfamily
PAM18_RS16110	COG2197	response regulator
PAM18_RS16135	COG2366	antibiotic biosynthetic process
PAM18_RS16150	COG0625	glutathione transferase activity
PAM18_RS16165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAM18_RS16170	COG0417	DNA replication proofreading
PAM18_RS16215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS16285	COG1309	transcriptional regulator
PAM18_RS16305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PAM18_RS16310	COG0583	DNA-binding transcription factor activity
PAM18_RS16320	COG2354	Protein conserved in bacteria
PAM18_RS16325	COG3278	Belongs to the heme-copper respiratory oxidase family
PAM18_RS16335	COG2239	Acts as a magnesium transporter
PAM18_RS16350	COG2203	Gaf domain
PAM18_RS16350	COG5001	Diguanylate cyclase
PAM18_RS16350	COG3706	GGDEF domain
PAM18_RS16350	COG4251	negative regulation of phosphorylation
PAM18_RS16355	COG4977	sequence-specific DNA binding
PAM18_RS16360	COG3813	Protein conserved in bacteria
PAM18_RS16425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAM18_RS16450	COG0604	alcohol dehydrogenase
PAM18_RS16455	COG0616	signal peptide processing
PAM18_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS16485	COG0583	DNA-binding transcription factor activity
PAM18_RS16510	COG1024	Enoyl-CoA hydratase
PAM18_RS16520	COG0531	amino acid
PAM18_RS16535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PAM18_RS16555	COG1388	LysM domain
PAM18_RS16555	COG0741	lytic transglycosylase activity
PAM18_RS16560	COG4166	transmembrane transport
PAM18_RS16565	COG4166	transmembrane transport
PAM18_RS16570	COG4174	ABC transporter (Permease)
PAM18_RS16575	COG4239	(ABC) transporter, permease
PAM18_RS16580	COG4172	Belongs to the ABC transporter superfamily
PAM18_RS16590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAM18_RS16605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PAM18_RS16625	COG0745	RESPONSE REGULATOR receiver
PAM18_RS16630	COG2205	protein histidine kinase activity
PAM18_RS16635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PAM18_RS16685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PAM18_RS16705	COG0589	response to stress
PAM18_RS16725	COG3707	response regulator
PAM18_RS16735	COG2223	nitrite transmembrane transporter activity
PAM18_RS16740	COG0515	serine threonine protein kinase
PAM18_RS16745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAM18_RS16750	COG2146	nitrite reductase [NAD(P)H] activity
PAM18_RS16755	COG0243	molybdopterin cofactor binding
PAM18_RS16775	COG0668	transmembrane transport
PAM18_RS16815	COG4067	protein conserved in archaea
PAM18_RS16815	COG0189	ligase activity
PAM18_RS16855	COG2909	trisaccharide binding
PAM18_RS16860	COG2909	trisaccharide binding
PAM18_RS16895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAM18_RS16945	COG0519	Catalyzes the synthesis of GMP from XMP
PAM18_RS16960	COG0667	Aldo Keto reductase
PAM18_RS16975	COG0183	Belongs to the thiolase family
PAM18_RS16995	COG1305	Transglutaminase-like
PAM18_RS17005	COG2308	Evidence 4 Homologs of previously reported genes of
PAM18_RS17030	COG1317	bacterial-type flagellum organization
PAM18_RS17140	COG4789	Type iii secretion
PAM18_RS17190	COG4790	Type iii secretion
PAM18_RS17195	COG4794	Type iii secretion
PAM18_RS17200	COG4791	protein targeting
PAM18_RS17205	COG4792	protein secretion
PAM18_RS17285	COG2840	Smr protein MutS2
PAM18_RS17305	COG2815	serine threonine protein kinase
PAM18_RS17305	COG0515	serine threonine protein kinase
PAM18_RS17345	COG2204	response regulator
PAM18_RS17385	COG0625	glutathione transferase activity
PAM18_RS17390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PAM18_RS17405	COG3135	benzoate transporter
PAM18_RS17420	COG2130	NADP-dependent
PAM18_RS17430	COG0840	transmembrane signaling receptor activity
PAM18_RS17440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PAM18_RS17480	COG0745	RESPONSE REGULATOR receiver
PAM18_RS17485	COG2205	protein histidine kinase activity
PAM18_RS17510	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS17520	COG1024	Enoyl-CoA hydratase
PAM18_RS17525	COG1250	3-hydroxyacyl-CoA dehydrogenase
PAM18_RS17530	COG2186	Transcriptional regulator
PAM18_RS17535	COG2807	transmembrane transport
PAM18_RS17540	COG0628	permease
PAM18_RS17550	COG0625	glutathione transferase activity
PAM18_RS17580	COG1022	Amp-dependent synthetase and ligase
PAM18_RS17610	COG0784	Response regulator, receiver
PAM18_RS17610	COG2205	protein histidine kinase activity
PAM18_RS17610	COG5002	protein histidine kinase activity
PAM18_RS17650	COG1846	Transcriptional regulator
PAM18_RS17655	COG2080	2 iron, 2 sulfur cluster binding
PAM18_RS17660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PAM18_RS17660	COG2010	Cytochrome c
PAM18_RS17665	COG2010	Cytochrome c
PAM18_RS17665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PAM18_RS17670	COG2207	Transcriptional regulator
PAM18_RS17745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PAM18_RS17750	COG1053	succinate dehydrogenase
PAM18_RS17755	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PAM18_RS17760	COG2009	succinate dehydrogenase
PAM18_RS17790	COG2084	Dehydrogenase
PAM18_RS17805	COG3738	Protein conserved in bacteria
PAM18_RS17830	COG0251	oxidation-reduction process
PAM18_RS17835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS17840	COG0174	glutamine synthetase
PAM18_RS17845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS17865	COG0840	transmembrane signaling receptor activity
PAM18_RS17880	COG3278	Belongs to the heme-copper respiratory oxidase family
PAM18_RS17895	COG2010	Cytochrome c
PAM18_RS17900	COG3278	Belongs to the heme-copper respiratory oxidase family
PAM18_RS17915	COG2010	Cytochrome c
PAM18_RS17920	COG0348	domain, Protein
PAM18_RS17930	COG2217	Heavy metal translocating P-type atpase
PAM18_RS17970	COG2076	Multidrug Resistance protein
PAM18_RS18000	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS18015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAM18_RS18040	COG1196	nuclear chromosome segregation
PAM18_RS18070	COG0402	S-adenosylhomocysteine deaminase activity
PAM18_RS18075	COG1247	-acetyltransferase
PAM18_RS18090	COG2963	transposase activity
PAM18_RS18095	COG2801	Transposase and inactivated derivatives
PAM18_RS18110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PAM18_RS18115	COG0384	phenazine biosynthesis protein PhzF
PAM18_RS18145	COG5006	permease, DMT superfamily
PAM18_RS18160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAM18_RS18175	COG3795	YCII-related domain
PAM18_RS18185	COG2814	Major facilitator Superfamily
PAM18_RS18190	COG4941	Belongs to the sigma-70 factor family
PAM18_RS18200	COG3795	YCII-related domain
PAM18_RS18210	COG2197	response regulator
PAM18_RS18220	COG0189	ligase activity
PAM18_RS18225	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS18240	COG0765	amino acid transport
PAM18_RS18245	COG0765	amino acid transport
PAM18_RS18250	COG1126	abc transporter atp-binding protein
PAM18_RS18275	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS18290	COG1253	flavin adenine dinucleotide binding
PAM18_RS18295	COG0300	oxidoreductase activity
PAM18_RS18305	COG0583	DNA-binding transcription factor activity
PAM18_RS18310	COG1864	DNA RNA non-specific endonuclease
PAM18_RS18310	COG3591	Belongs to the peptidase S1B family
PAM18_RS18315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PAM18_RS18320	COG4319	ketosteroid isomerase
PAM18_RS18335	COG4774	siderophore transport
PAM18_RS18380	COG2814	Major facilitator Superfamily
PAM18_RS18400	COG0583	DNA-binding transcription factor activity
PAM18_RS18410	COG0121	glutamine amidotransferase
PAM18_RS18440	COG3712	iron ion homeostasis
PAM18_RS18445	COG1595	DNA-templated transcription, initiation
PAM18_RS18460	COG1230	cation diffusion facilitator family transporter
PAM18_RS18465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PAM18_RS18490	COG2252	PERMEase
PAM18_RS18550	COG2233	PERMEase
PAM18_RS18565	COG1309	transcriptional regulator
PAM18_RS18575	COG3960	tartronate-semialdehyde synthase activity
PAM18_RS18580	COG3622	Belongs to the hyi family
PAM18_RS18585	COG2084	Dehydrogenase
PAM18_RS18595	COG0469	pyruvate kinase activity
PAM18_RS18600	COG4413	Urea transporter
PAM18_RS18605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PAM18_RS18620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PAM18_RS18630	COG3192	ethanolamine utilization protein
PAM18_RS18645	COG0446	pyridine nucleotide-disulphide oxidoreductase
PAM18_RS18650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAM18_RS18725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAM18_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS18740	COG1496	oxidoreductase activity
PAM18_RS18765	COG0835	chemotaxis
PAM18_RS18775	COG1192	Involved in chromosome partitioning
PAM18_RS18780	COG1360	Flagellar Motor Protein
PAM18_RS18785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PAM18_RS18795	COG0643	Histidine kinase
PAM18_RS18795	COG0784	Response regulator, receiver
PAM18_RS18795	COG2198	Histidine kinase
PAM18_RS18825	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAM18_RS18830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PAM18_RS18850	COG1987	bacterial-type flagellum assembly
PAM18_RS18890	COG2832	Protein of unknown function (DUF454)
PAM18_RS18905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS18910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS18920	COG5001	Diguanylate cyclase
PAM18_RS18920	COG3300	MHYT domain
PAM18_RS18955	COG0488	(ABC) transporter
PAM18_RS19010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAM18_RS19015	COG0583	DNA-binding transcription factor activity
PAM18_RS19030	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PAM18_RS19040	COG3264	Mechanosensitive ion channel
PAM18_RS19040	COG1196	nuclear chromosome segregation
PAM18_RS19045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PAM18_RS19045	COG0116	Belongs to the methyltransferase superfamily
PAM18_RS19055	COG0210	DNA helicase
PAM18_RS19080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PAM18_RS19155	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS19175	COG0406	alpha-ribazole phosphatase activity
PAM18_RS19205	COG0778	Nitroreductase
PAM18_RS19220	COG4206	TonB-dependent receptor
PAM18_RS19230	COG1802	Transcriptional regulator
PAM18_RS19240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS19275	COG0477	Major facilitator Superfamily
PAM18_RS19295	COG0765	amino acid transport
PAM18_RS19305	COG1126	abc transporter atp-binding protein
PAM18_RS19315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAM18_RS19320	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS19375	COG0784	Response regulator, receiver
PAM18_RS19375	COG4191	Histidine kinase
PAM18_RS19430	COG1289	transmembrane transporter activity
PAM18_RS19445	COG2207	Transcriptional regulator
PAM18_RS19465	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAM18_RS19470	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAM18_RS19480	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PAM18_RS19505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PAM18_RS19515	COG0318	PFAM AMP-dependent synthetase and ligase
PAM18_RS19520	COG0367	asparagine synthase
PAM18_RS19530	COG2211	Major facilitator Superfamily
PAM18_RS19580	COG1335	isochorismatase
PAM18_RS19585	COG0583	DNA-binding transcription factor activity
PAM18_RS19595	COG0791	NLP P60 protein
PAM18_RS19600	COG0791	NLP P60 protein
PAM18_RS19610	COG3829	transcription factor binding
PAM18_RS19625	COG2818	Glycosylase
PAM18_RS19650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PAM18_RS19655	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS19665	COG0625	glutathione transferase activity
PAM18_RS19685	COG3447	MASE1 domain protein
PAM18_RS19685	COG5002	protein histidine kinase activity
PAM18_RS19685	COG5001	Diguanylate cyclase
PAM18_RS19705	COG4459	periplasmic nitrate reductase
PAM18_RS19710	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
PAM18_RS19710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PAM18_RS19715	COG3062	negative regulation of establishment of protein localization
PAM18_RS19725	COG3043	anaerobic respiration
PAM18_RS19730	COG3005	denitrification pathway
PAM18_RS19735	COG2951	lytic endotransglycosylase activity
PAM18_RS19740	COG0861	Integral membrane protein TerC family
PAM18_RS19765	COG2977	Belongs to the P-Pant transferase superfamily
PAM18_RS19770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PAM18_RS19785	COG2226	methyltransferase
PAM18_RS19800	COG2205	protein histidine kinase activity
PAM18_RS19805	COG0745	RESPONSE REGULATOR receiver
PAM18_RS19810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PAM18_RS19810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAM18_RS19815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAM18_RS19820	COG1943	Transposase
PAM18_RS19845	COG0531	amino acid
PAM18_RS19875	COG0583	DNA-binding transcription factor activity
PAM18_RS19880	COG3257	ureidoglycine aminohydrolase activity
PAM18_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS19895	COG0604	alcohol dehydrogenase
PAM18_RS19895	COG3321	synthase
PAM18_RS19900	COG2197	response regulator
PAM18_RS19940	COG0583	DNA-binding transcription factor activity
PAM18_RS19945	COG0667	Aldo Keto reductase
PAM18_RS19970	COG0242	peptide deformylase activity
PAM18_RS19980	COG2199	diguanylate cyclase activity
PAM18_RS19985	COG2885	chlorophyll binding
PAM18_RS20015	COG1132	(ABC) transporter
PAM18_RS20025	COG4628	conserved protein (DUF2132)
PAM18_RS20030	COG2133	pyrroloquinoline quinone binding
PAM18_RS20045	COG2207	Transcriptional regulator
PAM18_RS20050	COG0477	Major facilitator Superfamily
PAM18_RS20065	COG2882	bacterial-type flagellum organization
PAM18_RS20120	COG1516	flagellar protein fliS
PAM18_RS20125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PAM18_RS20135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PAM18_RS20140	COG1216	Glycosyl transferase, family 2
PAM18_RS20140	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS20145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PAM18_RS20150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PAM18_RS20160	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PAM18_RS20190	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS20195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAM18_RS20215	COG1256	bacterial-type flagellum assembly
PAM18_RS20240	COG4787	bacterial-type flagellum-dependent cell motility
PAM18_RS20250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PAM18_RS20260	COG1815	bacterial-type flagellum-dependent cell motility
PAM18_RS20305	COG0326	Molecular chaperone. Has ATPase activity
PAM18_RS20320	COG3189	MarR family transcriptional regulator
PAM18_RS20340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PAM18_RS20355	COG2212	antiporter activity
PAM18_RS20360	COG1863	multisubunit Na H antiporter MnhE subunit
PAM18_RS20365	COG0651	ATP synthesis coupled electron transport
PAM18_RS20370	COG1006	Multisubunit Na H antiporter MnhC subunit
PAM18_RS20375	COG2111	Na H antiporter
PAM18_RS20375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PAM18_RS20380	COG3133	Outer membrane lipoprotein
PAM18_RS20390	COG1929	Belongs to the glycerate kinase type-1 family
PAM18_RS20395	COG2610	gluconate transmembrane transporter activity
PAM18_RS20400	COG3835	regulator
PAM18_RS20410	COG2885	chlorophyll binding
PAM18_RS20425	COG1199	ATP-dependent helicase activity
PAM18_RS20465	COG2860	membrane
PAM18_RS20480	COG0653	protein targeting
PAM18_RS20485	COG0625	glutathione transferase activity
PAM18_RS20510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS20515	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS20535	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS20540	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS20545	COG1024	Enoyl-CoA hydratase
PAM18_RS20550	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS20560	COG2814	Major facilitator Superfamily
PAM18_RS20565	COG2030	dehydratase
PAM18_RS20575	COG0183	Belongs to the thiolase family
PAM18_RS20605	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PAM18_RS20610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PAM18_RS20625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PAM18_RS20635	COG0425	Belongs to the sulfur carrier protein TusA family
PAM18_RS20690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAM18_RS20695	COG3188	usher protein
PAM18_RS20715	COG1051	belongs to the nudix hydrolase family
PAM18_RS20740	COG0602	queuosine metabolic process
PAM18_RS20745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PAM18_RS20775	COG0824	Thioesterase
PAM18_RS20805	COG0783	Belongs to the Dps family
PAM18_RS20850	COG3118	belongs to the thioredoxin family
PAM18_RS20885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PAM18_RS20900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PAM18_RS20940	COG3122	Protein conserved in bacteria
PAM18_RS20950	COG3956	TIGRFAM MazG family protein
PAM18_RS20955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAM18_RS20985	COG5002	protein histidine kinase activity
PAM18_RS20985	COG2205	protein histidine kinase activity
PAM18_RS20985	COG0784	Response regulator, receiver
PAM18_RS20990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAM18_RS21040	COG3038	cytochrome b561
PAM18_RS21055	COG4807	Protein conserved in bacteria
PAM18_RS21065	COG2239	Acts as a magnesium transporter
PAM18_RS21135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PAM18_RS21230	COG2301	Belongs to the HpcH HpaI aldolase family
PAM18_RS21240	COG2079	MmgE PrpD family protein
PAM18_RS21250	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS21255	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PAM18_RS21260	COG0583	DNA-binding transcription factor activity
PAM18_RS21265	COG0583	DNA-binding transcription factor activity
PAM18_RS21315	COG1113	amino acid transport
PAM18_RS21335	COG3321	synthase
PAM18_RS21335	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS21335	COG0604	alcohol dehydrogenase
PAM18_RS21345	COG5001	Diguanylate cyclase
PAM18_RS21345	COG5002	protein histidine kinase activity
PAM18_RS21365	COG0271	Belongs to the BolA IbaG family
PAM18_RS21405	COG0492	ferredoxin-NADP+ reductase activity
PAM18_RS21410	COG0450	alkyl hydroperoxide reductase
PAM18_RS21415	COG5001	Diguanylate cyclase
PAM18_RS21415	COG3447	MASE1 domain protein
PAM18_RS21415	COG5002	protein histidine kinase activity
PAM18_RS21445	COG1307	EDD domain protein, DegV family
PAM18_RS21455	COG1309	transcriptional regulator
PAM18_RS21460	COG0386	Belongs to the glutathione peroxidase family
PAM18_RS21480	COG0204	Acyl-transferase
PAM18_RS21485	COG2885	chlorophyll binding
PAM18_RS21490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PAM18_RS21505	COG2267	carboxylic ester hydrolase activity
PAM18_RS21540	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
PAM18_RS21570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAM18_RS21585	COG0546	phosphoglycolate phosphatase activity
PAM18_RS21600	COG3023	N-Acetylmuramoyl-L-alanine amidase
PAM18_RS21615	COG0656	L-ascorbic acid biosynthetic process
PAM18_RS21640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PAM18_RS21650	COG1802	Transcriptional regulator
PAM18_RS21660	COG0372	Belongs to the citrate synthase family
PAM18_RS21675	COG2079	MmgE PrpD family protein
PAM18_RS21690	COG1113	amino acid transport
PAM18_RS21720	COG0583	DNA-binding transcription factor activity
PAM18_RS21725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAM18_RS21735	COG4206	TonB-dependent receptor
PAM18_RS21745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PAM18_RS21810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAM18_RS21890	COG3180	Ammonia monooxygenase
PAM18_RS21900	COG2720	vancomycin resistance protein
PAM18_RS21915	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS21920	COG1024	Enoyl-CoA hydratase
PAM18_RS21940	COG2910	NAD(P)H-binding
PAM18_RS21945	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PAM18_RS22015	COG4974	Belongs to the 'phage' integrase family
PAM18_RS22025	COG4128	Pfam Zonular occludens toxin
PAM18_RS22105	COG0583	DNA-binding transcription factor activity
PAM18_RS22120	COG0463	Glycosyl transferase, family 2
PAM18_RS22130	COG0154	amidase activity
PAM18_RS22150	COG0583	DNA-binding transcription factor activity
PAM18_RS22160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PAM18_RS22195	COG2831	hemolysin activation secretion protein
PAM18_RS22340	COG0420	3'-5' exonuclease activity
PAM18_RS22350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PAM18_RS22355	COG1074	ATP-dependent DNA helicase activity
PAM18_RS22360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PAM18_RS22365	COG0095	Lipoate-protein ligase
PAM18_RS22370	COG0697	spore germination
PAM18_RS22385	COG0840	transmembrane signaling receptor activity
PAM18_RS22395	COG0306	phosphate transporter
PAM18_RS22455	COG4964	Belongs to the GSP D family
PAM18_RS22475	COG0433	COG0433 Predicted ATPase
PAM18_RS22510	COG0788	formyltetrahydrofolate deformylase activity
PAM18_RS22520	COG2925	Exonuclease
PAM18_RS22550	COG0714	Associated with various cellular activities
PAM18_RS22580	COG0589	response to stress
PAM18_RS22590	COG1024	Enoyl-CoA hydratase
PAM18_RS22600	COG3706	GGDEF domain
PAM18_RS22620	COG0693	protein deglycase activity
PAM18_RS22635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAM18_RS22650	COG0154	amidase activity
PAM18_RS22660	COG1473	amidohydrolase
PAM18_RS22675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PAM18_RS22680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PAM18_RS22680	COG0426	domain, Protein
PAM18_RS22700	COG0589	response to stress
PAM18_RS22715	COG2814	Major facilitator Superfamily
PAM18_RS22720	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS22735	COG1918	ferrous iron import across plasma membrane
PAM18_RS22750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PAM18_RS22790	COG1704	LemA family
PAM18_RS22815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS22820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS22835	COG3642	lipopolysaccharide core region biosynthetic process
PAM18_RS22845	COG2205	protein histidine kinase activity
PAM18_RS22850	COG0745	RESPONSE REGULATOR receiver
PAM18_RS22885	COG3030	protein affecting phage T7 exclusion by the F plasmid
PAM18_RS22895	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS22920	COG0668	transmembrane transport
PAM18_RS22930	COG0745	RESPONSE REGULATOR receiver
PAM18_RS22945	COG2096	Adenosyltransferase
PAM18_RS22950	COG0494	nUDIX hydrolase
PAM18_RS22970	COG1196	nuclear chromosome segregation
PAM18_RS22970	COG0741	lytic transglycosylase activity
PAM18_RS22970	COG0739	heme binding
PAM18_RS23015	COG0772	Belongs to the SEDS family
PAM18_RS23030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PAM18_RS23065	COG3107	peptidoglycan biosynthetic process
PAM18_RS23080	COG2823	Periplasmic or secreted lipoprotein
PAM18_RS23085	COG2969	positive regulation of protein catabolic process
PAM18_RS23090	COG0625	glutathione transferase activity
PAM18_RS23095	COG2857	Cytochrome c1
PAM18_RS23100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PAM18_RS23105	COG0723	plastoquinol--plastocyanin reductase activity
PAM18_RS23120	COG0667	Aldo Keto reductase
PAM18_RS23125	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS23140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PAM18_RS23150	COG2945	thiolester hydrolase activity
PAM18_RS23170	COG2951	lytic endotransglycosylase activity
PAM18_RS23180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAM18_RS23220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PAM18_RS23225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PAM18_RS23230	COG1127	ABC transporter
PAM18_RS23240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PAM18_RS23255	COG1137	ATPase activity
PAM18_RS23310	COG0312	modulator of DNA gyrase
PAM18_RS23320	COG0312	modulator of DNA gyrase
PAM18_RS23325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PAM18_RS23335	COG1530	ribonuclease E activity
PAM18_RS23350	COG1792	Involved in formation and maintenance of cell shape
PAM18_RS23355	COG1077	Cell shape determining protein MreB Mrl
PAM18_RS23375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PAM18_RS23380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAM18_RS23385	COG4676	Protein conserved in bacteria
PAM18_RS23390	COG5445	Predicted secreted protein (DUF2300)
PAM18_RS23405	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PAM18_RS23410	COG4676	Protein conserved in bacteria
PAM18_RS23415	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PAM18_RS23430	COG0747	negative chemotaxis
PAM18_RS23435	COG0747	negative chemotaxis
PAM18_RS23450	COG0747	negative chemotaxis
PAM18_RS23460	COG0747	negative chemotaxis
PAM18_RS23465	COG0601	transmembrane transport
PAM18_RS23470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAM18_RS23475	COG0444	Belongs to the ABC transporter superfamily
PAM18_RS23480	COG4608	Belongs to the ABC transporter superfamily
PAM18_RS23495	COG1984	allophanate hydrolase subunit 2
PAM18_RS23515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PAM18_RS23520	COG4774	siderophore transport
PAM18_RS23535	COG2194	sulfuric ester hydrolase activity
PAM18_RS23545	COG0019	diaminopimelate decarboxylase activity
PAM18_RS23585	COG4969	Belongs to the N-Me-Phe pilin family
PAM18_RS23650	COG1252	NADH dehydrogenase
PAM18_RS23655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PAM18_RS23660	COG2831	hemolysin activation secretion protein
PAM18_RS23730	COG4969	Belongs to the N-Me-Phe pilin family
PAM18_RS23770	COG1047	Peptidyl-prolyl cis-trans
PAM18_RS23785	COG0196	riboflavin kinase activity
PAM18_RS23800	COG3045	CreA protein
PAM18_RS23825	COG0142	geranyltranstransferase activity
PAM18_RS23840	COG0545	Peptidyl-prolyl cis-trans isomerase
PAM18_RS23860	COG1067	ATP-dependent peptidase activity
PAM18_RS23885	COG4650	regulator
PAM18_RS23900	COG1690	Belongs to the RtcB family
PAM18_RS23905	COG3541	Predicted nucleotidyltransferase
PAM18_RS23925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PAM18_RS23950	COG0577	efflux transmembrane transporter activity
PAM18_RS23950	COG1136	(ABC) transporter
PAM18_RS23955	COG0577	efflux transmembrane transporter activity
PAM18_RS23955	COG1136	(ABC) transporter
PAM18_RS23960	COG0488	(ABC) transporter
PAM18_RS23980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAM18_RS23985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS24010	COG0523	cobalamin synthesis protein
PAM18_RS24015	COG2879	small protein
PAM18_RS24020	COG1966	Carbon starvation protein
PAM18_RS24085	COG3608	succinylglutamate desuccinylase aspartoacylase
PAM18_RS24085	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PAM18_RS24090	COG2010	Cytochrome c
PAM18_RS24125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAM18_RS24135	COG0833	amino acid
PAM18_RS24140	COG2119	membrane
PAM18_RS24155	COG0501	Belongs to the peptidase M48B family
PAM18_RS24160	COG0840	transmembrane signaling receptor activity
PAM18_RS24165	COG2135	peptidase activity
PAM18_RS24170	COG1285	pathogenesis
PAM18_RS24230	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PAM18_RS24285	COG1090	epimerase
PAM18_RS24290	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PAM18_RS24300	COG0789	Transcriptional regulator
PAM18_RS24320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PAM18_RS24375	COG0012	GTP binding
PAM18_RS24385	COG4974	Belongs to the 'phage' integrase family
PAM18_RS24395	COG4128	Pfam Zonular occludens toxin
PAM18_RS24465	COG0288	reversible hydration of carbon dioxide
PAM18_RS24475	COG0456	acetyltransferase
PAM18_RS24520	COG1840	ABC-type Fe3 transport system, periplasmic component
PAM18_RS24525	COG1178	ABC-type Fe3 transport system permease component
PAM18_RS24530	COG3008	intermembrane lipid transfer
PAM18_RS24535	COG2995	paraquat-inducible protein a
PAM18_RS24540	COG2995	paraquat-inducible protein a
PAM18_RS24580	COG1183	phosphatidylcholine synthase activity
PAM18_RS24595	COG0028	Belongs to the TPP enzyme family
PAM18_RS24605	COG3098	single-species biofilm formation
PAM18_RS24615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PAM18_RS24650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAM18_RS24655	COG4558	Periplasmic binding protein
PAM18_RS24660	COG3720	iron ion transport
PAM18_RS24665	COG4771	TonB-dependent receptor
PAM18_RS24690	COG0436	Aminotransferase
PAM18_RS24700	COG2321	neutral zinc metallopeptidase
PAM18_RS24710	COG2252	PERMEase
PAM18_RS24725	COG0436	Aminotransferase
PAM18_RS24730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PAM18_RS24745	COG4191	Histidine kinase
PAM18_RS24845	COG0195	Participates in both transcription termination and antitermination
PAM18_RS24880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PAM18_RS24945	COG0497	DNA recombination
PAM18_RS24975	COG2186	Transcriptional regulator
PAM18_RS24980	COG1620	l-lactate permease
PAM18_RS25030	COG0697	spore germination
PAM18_RS25050	COG0697	spore germination
PAM18_RS25055	COG1522	sequence-specific DNA binding
PAM18_RS25065	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS25085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PAM18_RS25115	COG0509	glycine decarboxylation via glycine cleavage system
PAM18_RS25155	COG0531	amino acid
PAM18_RS25170	COG3276	selenocysteine insertion sequence binding
PAM18_RS25185	COG2864	formate dehydrogenase
PAM18_RS25190	COG0437	4 iron, 4 sulfur cluster binding
PAM18_RS25195	COG3383	formate dehydrogenase (NAD+) activity
PAM18_RS25195	COG0243	molybdopterin cofactor binding
PAM18_RS25200	COG3383	formate dehydrogenase (NAD+) activity
PAM18_RS25200	COG0243	molybdopterin cofactor binding
PAM18_RS25205	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PAM18_RS25210	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS25210	COG0446	pyridine nucleotide-disulphide oxidoreductase
PAM18_RS25235	COG0463	Glycosyl transferase, family 2
PAM18_RS25245	COG0534	Mate efflux family protein
PAM18_RS25255	COG1283	sodium-dependent phosphate transmembrane transporter activity
PAM18_RS25280	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PAM18_RS25305	COG4221	oxidoreductase activity
PAM18_RS25310	COG1272	protein, Hemolysin III
PAM18_RS25345	COG0023	Translation Initiation Factor
PAM18_RS25430	COG2095	MarC family integral membrane protein
PAM18_RS25435	COG0683	leucine binding
PAM18_RS25450	COG0411	ABC transporter
PAM18_RS25495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PAM18_RS25510	COG0443	Heat shock 70 kDa protein
PAM18_RS25535	COG0789	Transcriptional regulator
PAM18_RS25540	COG2982	Protein involved in outer membrane biogenesis
PAM18_RS25545	COG2193	ferroxidase activity
PAM18_RS25555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PAM18_RS25560	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PAM18_RS25620	COG3712	iron ion homeostasis
PAM18_RS25625	COG1595	DNA-templated transcription, initiation
PAM18_RS25645	COG2814	Major facilitator Superfamily
PAM18_RS25655	COG0583	DNA-binding transcription factor activity
PAM18_RS25680	COG4221	oxidoreductase activity
PAM18_RS25685	COG2423	ornithine cyclodeaminase activity
PAM18_RS25715	COG0583	DNA-binding transcription factor activity
PAM18_RS25730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PAM18_RS25790	COG3300	MHYT domain
PAM18_RS25790	COG5001	Diguanylate cyclase
PAM18_RS25800	COG0305	Participates in initiation and elongation during chromosome replication
PAM18_RS25830	COG0557	exoribonuclease II activity
PAM18_RS25860	COG0330	HflC and HflK could
PAM18_RS25865	COG0330	HflC and HflK could
PAM18_RS25870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PAM18_RS25890	COG0860	N-Acetylmuramoyl-L-alanine amidase
PAM18_RS25895	COG0802	atpase or kinase
PAM18_RS25900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PAM18_RS25900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PAM18_RS25950	COG5001	Diguanylate cyclase
PAM18_RS25950	COG3300	MHYT domain
PAM18_RS25955	COG0560	Phosphoserine phosphatase
PAM18_RS25955	COG3830	Belongs to the UPF0237 family
PAM18_RS25965	COG1988	membrane-bound metal-dependent
PAM18_RS25980	COG3577	Aspartyl protease
PAM18_RS25995	COG3150	esterase
PAM18_RS26000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PAM18_RS26010	COG0494	nUDIX hydrolase
PAM18_RS26025	COG1538	Outer membrane efflux protein
PAM18_RS26030	COG2249	NAD(P)H dehydrogenase (quinone) activity
PAM18_RS26045	COG0045	succinate-CoA ligase (ADP-forming) activity
PAM18_RS26050	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS26055	COG1024	Enoyl-CoA hydratase
PAM18_RS26060	COG0833	amino acid
PAM18_RS26090	COG0446	pyridine nucleotide-disulphide oxidoreductase
PAM18_RS26090	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS26100	COG1519	Transferase
PAM18_RS26105	COG0583	DNA-binding transcription factor activity
PAM18_RS26120	COG0667	Aldo Keto reductase
PAM18_RS26130	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS26135	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS26140	COG0367	asparagine synthase
PAM18_RS26165	COG1215	transferase activity, transferring glycosyl groups
PAM18_RS26185	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS26190	COG2192	nodulation
PAM18_RS26215	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS26220	COG0859	PFAM glycosyl transferase family 9
PAM18_RS26225	COG0859	PFAM glycosyl transferase family 9
PAM18_RS26260	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PAM18_RS26265	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS26275	COG3264	Mechanosensitive ion channel
PAM18_RS26275	COG1196	nuclear chromosome segregation
PAM18_RS26285	COG0730	response to heat
PAM18_RS26290	COG2873	o-acetylhomoserine
PAM18_RS26305	COG1192	Involved in chromosome partitioning
PAM18_RS26310	COG0583	DNA-binding transcription factor activity
PAM18_RS26315	COG2814	Major facilitator Superfamily
PAM18_RS26340	COG0493	'glutamate synthase
PAM18_RS26345	COG0067	glutamate synthase
PAM18_RS26345	COG0069	glutamate synthase activity
PAM18_RS26345	COG0070	glutamate synthase
PAM18_RS26395	COG0281	malic enzyme
PAM18_RS26415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAM18_RS26525	COG0840	transmembrane signaling receptor activity
PAM18_RS26535	COG1126	abc transporter atp-binding protein
PAM18_RS26540	COG0765	amino acid transport
PAM18_RS26570	COG1051	belongs to the nudix hydrolase family
PAM18_RS26575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PAM18_RS26580	COG0251	oxidation-reduction process
PAM18_RS26605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAM18_RS26625	COG2986	histidine ammonia-lyase
PAM18_RS26630	COG4175	Glycine betaine
PAM18_RS26635	COG4176	ABC-type proline glycine betaine transport system permease component
PAM18_RS26655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PAM18_RS26690	COG0402	S-adenosylhomocysteine deaminase activity
PAM18_RS26740	COG0789	Transcriptional regulator
PAM18_RS26745	COG1217	gtp-binding protein TYPA
PAM18_RS26765	COG0668	transmembrane transport
PAM18_RS26780	COG3852	Histidine kinase
PAM18_RS26795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PAM18_RS26830	COG4942	peptidase
PAM18_RS26835	COG0793	Belongs to the peptidase S41A family
PAM18_RS26840	COG2861	carbohydrate metabolic process
PAM18_RS26900	COG0579	oxidoreductase
PAM18_RS26910	COG1194	a g-specific adenine glycosylase
PAM18_RS26920	COG0673	inositol 2-dehydrogenase activity
PAM18_RS26930	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS26965	COG1846	Transcriptional regulator
PAM18_RS26975	COG1566	PFAM secretion protein HlyD family protein
PAM18_RS26980	COG2814	Major facilitator Superfamily
PAM18_RS26990	COG1088	dTDP-glucose 4,6-dehydratase activity
PAM18_RS26995	COG1091	dTDP-4-dehydrorhamnose reductase activity
PAM18_RS27060	COG1218	3'(2'),5'-bisphosphate nucleotidase
PAM18_RS27065	COG0494	nUDIX hydrolase
PAM18_RS27070	COG1011	Hydrolase
PAM18_RS27075	COG1652	LysM domain
PAM18_RS27085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PAM18_RS27105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PAM18_RS27115	COG0824	Thioesterase
PAM18_RS27120	COG1454	alcohol dehydrogenase
PAM18_RS27125	COG1960	acyl-CoA dehydrogenase activity
PAM18_RS27130	COG1024	Enoyl-CoA hydratase
PAM18_RS27130	COG1250	3-hydroxyacyl-CoA dehydrogenase
PAM18_RS27140	COG0778	Nitroreductase
PAM18_RS27165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PAM18_RS27170	COG4067	protein conserved in archaea
PAM18_RS27170	COG0189	ligase activity
PAM18_RS27195	COG2183	response to ionizing radiation
PAM18_RS27225	COG0306	phosphate transporter
PAM18_RS27230	COG1392	Phosphate transport regulator
PAM18_RS27235	COG3025	triphosphatase activity
PAM18_RS27240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PAM18_RS27270	COG1178	ABC-type Fe3 transport system permease component
PAM18_RS27280	COG0583	DNA-binding transcription factor activity
PAM18_RS27295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PAM18_RS27305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PAM18_RS27310	COG0006	proline dipeptidase activity
PAM18_RS27330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PAM18_RS27340	COG0842	Transport permease protein
PAM18_RS27345	COG0842	Transport permease protein
PAM18_RS27345	COG1129	ABC transporter
PAM18_RS27350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAM18_RS27365	COG2271	Major facilitator Superfamily
PAM18_RS27380	COG2755	lipolytic protein G-D-S-L family
PAM18_RS27380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PAM18_RS27410	COG0586	Pfam SNARE associated Golgi protein
PAM18_RS27415	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PAM18_RS27420	COG2050	protein possibly involved in aromatic compounds catabolism
PAM18_RS27430	COG0672	)-iron permease
PAM18_RS27435	COG1280	lysine exporter protein (LysE YggA)
PAM18_RS27440	COG0861	Integral membrane protein TerC family
PAM18_RS27450	COG0488	(ABC) transporter
PAM18_RS27505	COG3275	phosphorelay sensor kinase activity
PAM18_RS27535	COG0598	Magnesium transport protein CorA
PAM18_RS27565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PAM18_RS27625	COG0432	Pfam Uncharacterised protein family UPF0047
PAM18_RS27630	COG0004	ammonium transporteR
PAM18_RS27635	COG0347	Belongs to the P(II) protein family
PAM18_RS27645	COG0606	chelatase, subunit chli
PAM18_RS27650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PAM18_RS27660	COG0583	DNA-binding transcription factor activity
PAM18_RS27675	COG0210	DNA helicase
PAM18_RS27680	COG0028	Belongs to the TPP enzyme family
PAM18_RS27690	COG0427	acetyl-CoA hydrolase
PAM18_RS27700	COG1917	Cupin 2, conserved barrel domain protein
PAM18_RS27700	COG1396	sequence-specific DNA binding
PAM18_RS27710	COG0251	oxidation-reduction process
PAM18_RS27740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PAM18_RS27745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAM18_RS27750	COG2814	Major facilitator Superfamily
PAM18_RS27755	COG1012	belongs to the aldehyde dehydrogenase family
PAM18_RS27760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PAM18_RS27780	COG0747	negative chemotaxis
PAM18_RS27795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAM18_RS27835	COG3245	cytochrome
PAM18_RS27855	COG0708	Exodeoxyribonuclease III
PAM18_RS27870	COG1561	YicC-like family, N-terminal region
PAM18_RS27885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAM18_RS27905	COG4753	response regulator
PAM18_RS27905	COG2207	Transcriptional regulator
PAM18_RS27915	COG0583	DNA-binding transcription factor activity
PAM18_RS27920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PAM18_RS27955	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PAM18_RS27960	COG0247	lactate metabolic process
PAM18_RS27965	COG0277	FAD linked oxidase domain protein
PAM18_RS27970	COG0277	FAD linked oxidase domain protein
PAM18_RS27975	COG2186	Transcriptional regulator
PAM18_RS28005	COG1253	flavin adenine dinucleotide binding
PAM18_RS28010	COG0739	heme binding
PAM18_RS28030	COG0573	inorganic phosphate transmembrane transporter activity
PAM18_RS28070	COG0477	Major facilitator Superfamily
PAM18_RS28075	COG1607	acyl-coa hydrolase
PAM18_RS28095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PAM18_RS28100	COG4175	Glycine betaine
PAM18_RS28105	COG4176	ABC-type proline glycine betaine transport system permease component
PAM18_RS28115	COG1760	l-serine dehydratase
PAM18_RS28130	COG0583	DNA-binding transcription factor activity
PAM18_RS28140	COG0657	acetylesterase activity
PAM18_RS28155	COG3246	L-lysine catabolic process to acetate
PAM18_RS28210	COG1902	pentaerythritol trinitrate reductase activity
PAM18_RS28210	COG0446	pyridine nucleotide-disulphide oxidoreductase
PAM18_RS28215	COG2181	nitrate reductase activity
PAM18_RS28215	COG0247	lactate metabolic process
PAM18_RS28235	COG3655	Transcriptional regulator
PAM18_RS28275	COG1017	nitric oxide dioxygenase activity
PAM18_RS28275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAM18_RS28360	COG0583	DNA-binding transcription factor activity
PAM18_RS28370	COG2391	methyltransferase activity
PAM18_RS28395	COG0511	ligase activity, forming carbon-carbon bonds
PAM18_RS28395	COG5016	pyruvate
PAM18_RS28400	COG0439	Biotin carboxylase
PAM18_RS28405	COG0583	DNA-binding transcription factor activity
PAM18_RS28420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PAM18_RS28425	COG0826	peptidase U32
PAM18_RS28445	COG0210	DNA helicase
PAM18_RS28455	COG0427	acetyl-CoA hydrolase
PAM18_RS28470	COG0438	transferase activity, transferring glycosyl groups
PAM18_RS28515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PAM18_RS28520	COG2755	lipolytic protein G-D-S-L family
PAM18_RS28520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PAM18_RS28560	COG0679	Auxin Efflux Carrier
PAM18_RS28570	COG2851	Citrate transporter
PAM18_RS28575	COG0861	Integral membrane protein TerC family
PAM18_RS28580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PAM18_RS28585	COG1690	Belongs to the RtcB family
PAM18_RS28620	COG0700	Nucleoside recognition
PAM18_RS28625	COG1301	dicarboxylic acid transport
PAM18_RS28650	COG5002	protein histidine kinase activity
PAM18_RS28655	COG3023	N-Acetylmuramoyl-L-alanine amidase
PAM18_RS28660	COG2095	MarC family integral membrane protein
PAM18_RS28685	COG3245	cytochrome
PAM18_RS28720	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PAM18_RS28725	COG0735	belongs to the Fur family
PAM18_RS28735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PAM18_RS28750	COG2011	ABC-type metal ion transport system permease component
PAM18_RS28780	COG0531	amino acid
PAM18_RS28790	COG4191	Histidine kinase
PAM18_RS28825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PAM18_RS28825	COG4651	solute:proton antiporter activity
PAM18_RS28830	COG1607	acyl-coa hydrolase
PAM18_RS28840	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS28845	COG0174	glutamine synthetase
PAM18_RS28850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PAM18_RS28855	COG1028	Short-chain dehydrogenase reductase Sdr
PAM18_RS28880	COG4651	solute:proton antiporter activity
PAM18_RS28880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PAM18_RS28885	COG0477	Major facilitator Superfamily
PAM18_RS28895	COG0523	cobalamin synthesis protein
PAM18_RS28940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PAM18_RS28960	COG2358	TRAP transporter, solute receptor (TAXI family
PAM18_RS28965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PAM18_RS29020	COG1349	DNA-binding transcription factor activity
PAM18_RS29080	COG1475	DNA binding
PAM18_RS29085	COG1192	Involved in chromosome partitioning
PAM18_RS29130	COG0738	Major facilitator superfamily