locus-tag	class	description
U769_RS00035	COG2010	Cytochrome c
U769_RS00050	COG2818	Glycosylase
U769_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
U769_RS00080	COG0569	domain protein
U769_RS00100	COG1652	LysM domain
U769_RS00105	COG0758	DNA mediated transformation
U769_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U769_RS00155	COG3119	arylsulfatase activity
U769_RS00160	COG0583	DNA-binding transcription factor activity
U769_RS00195	COG3360	Dodecin
U769_RS00210	COG3210	domain, Protein
U769_RS00245	COG3174	membrane
U769_RS00285	COG0367	asparagine synthase
U769_RS00305	COG0583	DNA-binding transcription factor activity
U769_RS00320	COG1764	response to oxidative stress
U769_RS00355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
U769_RS00360	COG0339	signal peptide processing
U769_RS00365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
U769_RS00380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
U769_RS00395	COG2815	serine threonine protein kinase
U769_RS00395	COG0515	serine threonine protein kinase
U769_RS00400	COG0631	protein serine/threonine phosphatase activity
U769_RS00415	COG1360	Flagellar Motor Protein
U769_RS00545	COG0659	secondary active sulfate transmembrane transporter activity
U769_RS00555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
U769_RS00560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
U769_RS00565	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
U769_RS00605	COG2153	protein acetylation
U769_RS00645	COG0583	DNA-binding transcription factor activity
U769_RS00670	COG2824	Alkylphosphonate utilization operon protein PhnA
U769_RS00700	COG0402	S-adenosylhomocysteine deaminase activity
U769_RS00710	COG3845	ABC transporter
U769_RS00715	COG4603	Belongs to the binding-protein-dependent transport system permease family
U769_RS00720	COG1079	Belongs to the binding-protein-dependent transport system permease family
U769_RS00795	COG0583	DNA-binding transcription factor activity
U769_RS00800	COG3485	protocatechuate 3,4-dioxygenase
U769_RS00805	COG3485	protocatechuate 3,4-dioxygenase
U769_RS00810	COG1414	Transcriptional regulator
U769_RS00825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS00830	COG0583	DNA-binding transcription factor activity
U769_RS00865	COG2233	PERMEase
U769_RS00870	COG1309	transcriptional regulator
U769_RS00905	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
U769_RS00920	COG0835	chemotaxis
U769_RS00925	COG2198	Histidine kinase
U769_RS00925	COG0643	Histidine kinase
U769_RS00930	COG0745	RESPONSE REGULATOR receiver
U769_RS00940	COG0583	DNA-binding transcription factor activity
U769_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS00955	COG1116	anion transmembrane transporter activity
U769_RS00960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U769_RS00965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS00995	COG2175	clavaminate synthase activity
U769_RS01070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
U769_RS01100	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS01105	COG1113	amino acid transport
U769_RS01120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U769_RS01125	COG0235	Class ii aldolase
U769_RS01130	COG1396	sequence-specific DNA binding
U769_RS01135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U769_RS01140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
U769_RS01150	COG0477	Major facilitator Superfamily
U769_RS01160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
U769_RS01165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U769_RS01170	COG0583	DNA-binding transcription factor activity
U769_RS01190	COG0673	inositol 2-dehydrogenase activity
U769_RS01210	COG2271	Major facilitator Superfamily
U769_RS01220	COG1309	transcriptional regulator
U769_RS01225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
U769_RS01235	COG0477	Major facilitator Superfamily
U769_RS01255	COG2239	Acts as a magnesium transporter
U769_RS01360	COG0745	RESPONSE REGULATOR receiver
U769_RS01370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U769_RS01385	COG0583	DNA-binding transcription factor activity
U769_RS01410	COG0501	Belongs to the peptidase M48B family
U769_RS01430	COG4208	sulfate ABC transporter
U769_RS01440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
U769_RS01460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U769_RS01475	COG2199	diguanylate cyclase activity
U769_RS01500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
U769_RS01505	COG0174	glutamine synthetase
U769_RS01510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
U769_RS01515	COG0174	glutamine synthetase
U769_RS01535	COG3842	ATPase activity
U769_RS01540	COG1176	ABC-type spermidine putrescine transport system, permease component I
U769_RS01545	COG1177	transmembrane transport
U769_RS01595	COG0765	amino acid transport
U769_RS01610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U769_RS01615	COG0277	FAD linked oxidase domain protein
U769_RS01620	COG0179	Fumarylacetoacetate (FAA) hydrolase
U769_RS01630	COG3111	PFAM Bacterial OB fold (BOF) protein
U769_RS01640	COG0531	amino acid
U769_RS01645	COG2182	Extracellular solute-binding protein
U769_RS01650	COG1177	transmembrane transport
U769_RS01660	COG3842	ATPase activity
U769_RS01665	COG3204	pilus organization
U769_RS01670	COG2234	aminopeptidase activity
U769_RS01685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U769_RS01695	COG0702	epimerase
U769_RS01735	COG0730	response to heat
U769_RS01770	COG0584	glycerophosphoryl diester phosphodiesterase
U769_RS01790	COG0622	Phosphoesterase
U769_RS01795	COG2233	PERMEase
U769_RS01810	COG0693	protein deglycase activity
U769_RS01850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
U769_RS01860	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
U769_RS01885	COG0429	hydrolase of the alpha beta-hydrolase fold
U769_RS01895	COG0742	ribosomal rna small subunit methyltransferase
U769_RS01900	COG0612	Peptidase, M16
U769_RS01905	COG0612	Peptidase, M16
U769_RS01910	COG0552	protein localization to endoplasmic reticulum
U769_RS01915	COG2884	Cell division ATP-binding protein ftsE
U769_RS01920	COG2177	Part of the ABC transporter FtsEX involved in
U769_RS01940	COG2363	Small membrane protein
U769_RS01975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
U769_RS01990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
U769_RS01990	COG2813	Specifically methylates the guanine in position
U769_RS02000	COG1160	GTP binding
U769_RS02005	COG1872	DUF167
U769_RS02050	COG0626	cystathionine gamma-synthase activity
U769_RS02115	COG2198	Histidine kinase
U769_RS02115	COG0643	Histidine kinase
U769_RS02115	COG0784	Response regulator, receiver
U769_RS02145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
U769_RS02160	COG3038	cytochrome b561
U769_RS02190	COG0513	Belongs to the DEAD box helicase family
U769_RS02200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
U769_RS02205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U769_RS02230	COG1309	transcriptional regulator
U769_RS02235	COG0402	S-adenosylhomocysteine deaminase activity
U769_RS02240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U769_RS02250	COG0493	'glutamate synthase
U769_RS02265	COG1953	Uracil, thiamine, allantoin
U769_RS02280	COG1960	acyl-CoA dehydrogenase activity
U769_RS02285	COG0583	DNA-binding transcription factor activity
U769_RS02295	COG0306	phosphate transporter
U769_RS02305	COG0330	HflC and HflK could
U769_RS02315	COG1289	transmembrane transporter activity
U769_RS02320	COG0513	Belongs to the DEAD box helicase family
U769_RS02330	COG0189	ligase activity
U769_RS02330	COG4067	protein conserved in archaea
U769_RS02335	COG0477	Major facilitator Superfamily
U769_RS02340	COG0542	response to heat
U769_RS02350	COG0204	Acyl-transferase
U769_RS02360	COG0745	RESPONSE REGULATOR receiver
U769_RS02365	COG2205	protein histidine kinase activity
U769_RS02370	COG4452	Inner membrane protein CreD
U769_RS02400	COG4774	siderophore transport
U769_RS02405	COG3712	iron ion homeostasis
U769_RS02410	COG1595	DNA-templated transcription, initiation
U769_RS02415	COG0625	glutathione transferase activity
U769_RS02425	COG1309	transcriptional regulator
U769_RS02430	COG1953	Uracil, thiamine, allantoin
U769_RS02450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
U769_RS02485	COG3585	molybdate ion transport
U769_RS02485	COG2005	Transcriptional regulator
U769_RS02490	COG5544	Lipoprotein
U769_RS02495	COG1040	competence protein
U769_RS02515	COG0511	ligase activity, forming carbon-carbon bonds
U769_RS02530	COG1984	allophanate hydrolase subunit 2
U769_RS02550	COG1073	alpha beta
U769_RS02550	COG2226	methyltransferase
U769_RS02570	COG1960	acyl-CoA dehydrogenase activity
U769_RS02575	COG1960	acyl-CoA dehydrogenase activity
U769_RS02580	COG1960	acyl-CoA dehydrogenase activity
U769_RS02590	COG1648	precorrin-2 dehydrogenase activity
U769_RS02590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
U769_RS02675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U769_RS02680	COG0583	DNA-binding transcription factor activity
U769_RS02685	COG2258	MOSC domain
U769_RS02695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
U769_RS02715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS02725	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
U769_RS02780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U769_RS02785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
U769_RS02795	COG3622	Belongs to the hyi family
U769_RS02800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
U769_RS02840	COG2081	HI0933 family
U769_RS02845	COG1451	nucleotide metabolic process
U769_RS02855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
U769_RS02860	COG3152	Membrane
U769_RS02865	COG4977	sequence-specific DNA binding
U769_RS02865	COG1917	Cupin 2, conserved barrel domain protein
U769_RS02870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U769_RS02965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
U769_RS02985	COG2719	SpoVR family
U769_RS02995	COG2766	serine protein kinase
U769_RS03045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
U769_RS03060	COG2197	response regulator
U769_RS03070	COG3842	ATPase activity
U769_RS03080	COG1176	ABC-type spermidine putrescine transport system, permease component I
U769_RS03090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
U769_RS03115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U769_RS03200	COG3179	chitinase
U769_RS03325	COG1765	OsmC-like protein
U769_RS03340	COG0537	adenosine 5'-monophosphoramidase activity
U769_RS03365	COG1981	membrane
U769_RS03395	COG0739	heme binding
U769_RS03560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
U769_RS03685	COG2814	Major facilitator Superfamily
U769_RS03710	COG1021	2,3-dihydroxybenzoate-AMP ligase
U769_RS03720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U769_RS03720	COG3433	isochorismatase activity
U769_RS03720	COG2226	methyltransferase
U769_RS03725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U769_RS03725	COG3433	isochorismatase activity
U769_RS03725	COG2226	methyltransferase
U769_RS03735	COG1132	(ABC) transporter
U769_RS03735	COG2375	cellular response to nickel ion
U769_RS03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS03820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS03830	COG2706	6-phosphogluconolactonase activity
U769_RS03850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U769_RS03855	COG1960	acyl-CoA dehydrogenase activity
U769_RS03865	COG4191	Histidine kinase
U769_RS03870	COG4566	intracellular signal transduction
U769_RS03880	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS03885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U769_RS03890	COG2271	Major facilitator Superfamily
U769_RS03935	COG2226	methyltransferase
U769_RS03945	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS03950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS03970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U769_RS03985	COG0251	oxidation-reduction process
U769_RS03995	COG0693	protein deglycase activity
U769_RS04000	COG0492	ferredoxin-NADP+ reductase activity
U769_RS04005	COG1959	2 iron, 2 sulfur cluster binding
U769_RS04040	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U769_RS04045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U769_RS04050	COG4592	Periplasmic binding protein
U769_RS04055	COG1120	ATPase activity
U769_RS04065	COG1629	transport
U769_RS04065	COG4774	siderophore transport
U769_RS04070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U769_RS04075	COG4991	sh3 domain protein
U769_RS04080	COG1063	alcohol dehydrogenase
U769_RS04090	COG0022	dehydrogenase e1 component
U769_RS04095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
U769_RS04100	COG3199	ATP-NAD kinase
U769_RS04110	COG3284	Transcriptional regulator
U769_RS04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS04165	COG2814	Major facilitator Superfamily
U769_RS04170	COG1846	Transcriptional regulator
U769_RS04180	COG3278	Belongs to the heme-copper respiratory oxidase family
U769_RS04185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U769_RS04195	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U769_RS04210	COG3971	2-oxopent-4-enoate hydratase activity
U769_RS04215	COG2271	Major facilitator Superfamily
U769_RS04225	COG3384	dioxygenase
U769_RS04230	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS04270	COG1611	Belongs to the LOG family
U769_RS04315	COG0583	DNA-binding transcription factor activity
U769_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS04340	COG1063	alcohol dehydrogenase
U769_RS04345	COG2271	Major facilitator Superfamily
U769_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS04400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
U769_RS04415	COG3121	Chaperone
U769_RS04420	COG3188	usher protein
U769_RS04440	COG2197	response regulator
U769_RS04480	COG0531	amino acid
U769_RS04500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U769_RS04510	COG3047	cAMP biosynthetic process
U769_RS04540	COG3118	belongs to the thioredoxin family
U769_RS04545	COG2264	protein methyltransferase activity
U769_RS04560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U769_RS04560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
U769_RS04585	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
U769_RS04590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
U769_RS04600	COG3577	Aspartyl protease
U769_RS04625	COG0142	geranyltranstransferase activity
U769_RS04635	COG4948	Mandelate Racemase Muconate Lactonizing
U769_RS04655	COG1131	(ABC) transporter
U769_RS04660	COG5002	protein histidine kinase activity
U769_RS04680	COG0745	RESPONSE REGULATOR receiver
U769_RS04690	COG3228	Belongs to the MtfA family
U769_RS04695	COG0586	Pfam SNARE associated Golgi protein
U769_RS04710	COG0456	acetyltransferase
U769_RS04720	COG4303	Ethanolamine ammonia lyase large subunit
U769_RS04725	COG0531	amino acid
U769_RS04735	COG3284	Transcriptional regulator
U769_RS04740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
U769_RS04755	COG0702	epimerase
U769_RS04775	COG1346	cytolysis
U769_RS04785	COG0586	Pfam SNARE associated Golgi protein
U769_RS04825	COG0768	penicillin binding
U769_RS04830	COG0772	Belongs to the SEDS family
U769_RS04835	COG2951	lytic endotransglycosylase activity
U769_RS04845	COG1686	Belongs to the peptidase S11 family
U769_RS04875	COG2951	lytic endotransglycosylase activity
U769_RS04910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
U769_RS04920	COG4535	Mg2 and Co2 transporter CorC
U769_RS04930	COG1702	phosphate starvation-inducible protein PhoH
U769_RS04960	COG0351	phosphomethylpyrimidine kinase
U769_RS04965	COG2205	protein histidine kinase activity
U769_RS04965	COG2198	Histidine kinase
U769_RS04965	COG0784	Response regulator, receiver
U769_RS04975	COG1960	acyl-CoA dehydrogenase activity
U769_RS04985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
U769_RS05025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
U769_RS05035	COG1643	Atp-dependent helicase
U769_RS05080	COG3416	Protein conserved in bacteria
U769_RS05090	COG0513	Belongs to the DEAD box helicase family
U769_RS05100	COG2197	response regulator
U769_RS05105	COG2202	Pas domain
U769_RS05105	COG2199	diguanylate cyclase activity
U769_RS05105	COG2200	EAL domain
U769_RS05110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS05110	COG2205	protein histidine kinase activity
U769_RS05130	COG1946	Acyl-CoA thioesterase
U769_RS05150	COG4521	taurine ABC transporter
U769_RS05160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U769_RS05165	COG2175	clavaminate synthase activity
U769_RS05170	COG1297	OPT oligopeptide transporter protein
U769_RS05175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U769_RS05190	COG1271	oxidase subunit
U769_RS05195	COG1294	oxidase, subunit
U769_RS05205	COG2207	Transcriptional regulator
U769_RS05215	COG0183	Belongs to the thiolase family
U769_RS05220	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS05245	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
U769_RS05270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
U769_RS05280	COG0521	Mo-molybdopterin cofactor biosynthetic process
U769_RS05285	COG0303	'Molybdopterin
U769_RS05290	COG0826	peptidase U32
U769_RS05295	COG0826	peptidase U32
U769_RS05300	COG3154	lipid carrier protein
U769_RS05350	COG4772	TonB-dependent receptor
U769_RS05355	COG3712	iron ion homeostasis
U769_RS05360	COG1595	DNA-templated transcription, initiation
U769_RS05370	COG0697	spore germination
U769_RS05380	COG0583	DNA-binding transcription factor activity
U769_RS05400	COG1566	PFAM secretion protein HlyD family protein
U769_RS05450	COG0300	oxidoreductase activity
U769_RS05455	COG2226	methyltransferase
U769_RS05470	COG2197	response regulator
U769_RS05475	COG3850	Histidine kinase
U769_RS05485	COG2223	nitrite transmembrane transporter activity
U769_RS05490	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
U769_RS05495	COG1140	nitrate reductase beta subunit
U769_RS05500	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
U769_RS05505	COG2181	nitrate reductase activity
U769_RS05510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U769_RS05525	COG4771	TonB-dependent receptor
U769_RS05530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS05555	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS05565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS05630	COG0583	DNA-binding transcription factor activity
U769_RS05645	COG0640	Transcriptional regulator
U769_RS05670	COG0471	metal ion transport
U769_RS05670	COG0490	domain, Protein
U769_RS05675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
U769_RS05680	COG4120	Belongs to the binding-protein-dependent transport system permease family
U769_RS05730	COG0795	lipopolysaccharide-transporting ATPase activity
U769_RS05735	COG0795	lipopolysaccharide-transporting ATPase activity
U769_RS05745	COG2200	EAL domain
U769_RS05765	COG1862	Preprotein translocase
U769_RS05780	COG3134	Outer membrane lipoprotein
U769_RS05795	COG1045	serine acetyltransferase
U769_RS05885	COG0436	Aminotransferase
U769_RS05900	COG0667	Aldo Keto reductase
U769_RS05940	COG0739	heme binding
U769_RS05950	COG2847	Copper chaperone PCu(A)C
U769_RS05960	COG1335	isochorismatase
U769_RS05975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
U769_RS05985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
U769_RS05990	COG0583	DNA-binding transcription factor activity
U769_RS06040	COG2132	Multicopper oxidase
U769_RS06045	COG0590	tRNA wobble adenosine to inosine editing
U769_RS06080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U769_RS06080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
U769_RS06085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
U769_RS06090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
U769_RS06095	COG2188	Transcriptional regulator
U769_RS06135	COG0477	Major facilitator Superfamily
U769_RS06140	COG4536	flavin adenine dinucleotide binding
U769_RS06150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
U769_RS06175	COG1607	acyl-coa hydrolase
U769_RS06195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
U769_RS06220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
U769_RS06245	COG2255	four-way junction helicase activity
U769_RS06260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
U769_RS06270	COG1902	pentaerythritol trinitrate reductase activity
U769_RS06315	COG2197	response regulator
U769_RS06320	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
U769_RS06340	COG0477	Major facilitator Superfamily
U769_RS06375	COG2203	Gaf domain
U769_RS06375	COG3706	GGDEF domain
U769_RS06375	COG4251	negative regulation of phosphorylation
U769_RS06375	COG5001	Diguanylate cyclase
U769_RS06380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
U769_RS06410	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
U769_RS06410	COG3064	Membrane
U769_RS06410	COG1073	alpha beta
U769_RS06425	COG2885	chlorophyll binding
U769_RS06440	COG0789	Transcriptional regulator
U769_RS06460	COG1214	PFAM Peptidase M22, glycoprotease
U769_RS06470	COG1801	Protein of unknown function DUF72
U769_RS06475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
U769_RS06500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS06545	COG2166	iron-sulfur cluster assembly
U769_RS06560	COG1280	lysine exporter protein (LysE YggA)
U769_RS06565	COG1393	Belongs to the ArsC family
U769_RS06585	COG0025	NhaP-type Na H and K H
U769_RS06590	COG0436	Aminotransferase
U769_RS06600	COG0024	Methionine aminopeptidase
U769_RS06680	COG1115	amino acid carrier protein
U769_RS06730	COG2391	methyltransferase activity
U769_RS06735	COG0583	DNA-binding transcription factor activity
U769_RS06740	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
U769_RS06745	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
U769_RS06795	COG1546	Belongs to the CinA family
U769_RS06815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
U769_RS06820	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
U769_RS06825	COG3530	Putative quorum-sensing-regulated virulence factor
U769_RS06840	COG1177	transmembrane transport
U769_RS06845	COG1176	ABC-type spermidine putrescine transport system, permease component I
U769_RS06855	COG3148	PFAM DTW domain containing protein
U769_RS06875	COG0069	glutamate synthase activity
U769_RS06900	COG0531	amino acid
U769_RS06905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U769_RS06905	COG2169	Transcriptional regulator
U769_RS06910	COG0477	Major facilitator Superfamily
U769_RS06915	COG0583	DNA-binding transcription factor activity
U769_RS06920	COG1960	acyl-CoA dehydrogenase activity
U769_RS06925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
U769_RS06930	COG1024	Enoyl-CoA hydratase
U769_RS06935	COG1250	3-hydroxyacyl-CoA dehydrogenase
U769_RS06940	COG0183	Belongs to the thiolase family
U769_RS06950	COG0583	DNA-binding transcription factor activity
U769_RS06985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
U769_RS07025	COG2814	Major facilitator Superfamily
U769_RS07065	COG0583	DNA-binding transcription factor activity
U769_RS07075	COG0084	hydrolase, TatD family'
U769_RS07080	COG1609	Transcriptional regulator
U769_RS07085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
U769_RS07085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
U769_RS07090	COG1105	Belongs to the carbohydrate kinase PfkB family
U769_RS07095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U769_RS07095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
U769_RS07095	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
U769_RS07205	COG3842	ATPase activity
U769_RS07225	COG0243	molybdopterin cofactor binding
U769_RS07230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
U769_RS07235	COG2223	nitrite transmembrane transporter activity
U769_RS07250	COG0450	alkyl hydroperoxide reductase
U769_RS07280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS07315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
U769_RS07320	COG2264	protein methyltransferase activity
U769_RS07330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
U769_RS07385	COG0489	protein tyrosine kinase activity
U769_RS07430	COG0791	NLP P60 protein
U769_RS07445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
U769_RS07450	COG0668	transmembrane transport
U769_RS07455	COG0477	Major facilitator Superfamily
U769_RS07460	COG0513	Belongs to the DEAD box helicase family
U769_RS07480	COG5002	protein histidine kinase activity
U769_RS07480	COG2205	protein histidine kinase activity
U769_RS07480	COG0784	Response regulator, receiver
U769_RS07485	COG1363	Peptidase, m42
U769_RS07490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
U769_RS07490	COG0189	ligase activity
U769_RS07495	COG0367	asparagine synthase
U769_RS07520	COG0183	Belongs to the thiolase family
U769_RS07540	COG0450	alkyl hydroperoxide reductase
U769_RS07545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS07550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U769_RS07560	COG0431	NADPH-dependent FMN reductase
U769_RS07565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS07575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U769_RS07600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
U769_RS07625	COG0583	DNA-binding transcription factor activity
U769_RS07630	COG1380	Effector of murein hydrolase LrgA
U769_RS07635	COG1346	cytolysis
U769_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS07660	COG1024	Enoyl-CoA hydratase
U769_RS07670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
U769_RS07715	COG0508	dehydrogenase complex catalyzes the overall conversion of
U769_RS07755	COG1629	transport
U769_RS07810	COG0583	DNA-binding transcription factor activity
U769_RS07885	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
U769_RS07890	COG3639	organic phosphonate transmembrane transporter activity
U769_RS07895	COG2188	Transcriptional regulator
U769_RS07900	COG3624	Phosphonate C-P lyase system protein PhnG
U769_RS07910	COG3626	phosphonate metabolism
U769_RS07915	COG3627	carbon phosphorus lyase activity
U769_RS07920	COG4107	phosphonate C-P lyase system protein PhnK
U769_RS07925	COG4778	phosphonate C-P lyase system protein PhnL
U769_RS07930	COG3454	Phosphonate metabolism
U769_RS07940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
U769_RS08040	COG1566	PFAM secretion protein HlyD family protein
U769_RS08050	COG0697	spore germination
U769_RS08075	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
U769_RS08095	COG0835	chemotaxis
U769_RS08095	COG0784	Response regulator, receiver
U769_RS08110	COG0745	RESPONSE REGULATOR receiver
U769_RS08120	COG0514	ATP-dependent DNA helicase (RecQ)
U769_RS08125	COG5001	Diguanylate cyclase
U769_RS08125	COG4251	negative regulation of phosphorylation
U769_RS08125	COG3706	GGDEF domain
U769_RS08125	COG2203	Gaf domain
U769_RS08145	COG1752	Esterase of the alpha-beta hydrolase superfamily
U769_RS08185	COG2124	cytochrome p450
U769_RS08190	COG4221	oxidoreductase activity
U769_RS08205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U769_RS08235	COG0583	DNA-binding transcription factor activity
U769_RS08265	COG3639	organic phosphonate transmembrane transporter activity
U769_RS08275	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
U769_RS08280	COG2084	Dehydrogenase
U769_RS08295	COG0589	response to stress
U769_RS08335	COG2814	Major facilitator Superfamily
U769_RS08340	COG2030	dehydratase
U769_RS08345	COG2267	carboxylic ester hydrolase activity
U769_RS08350	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS08355	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS08360	COG1643	Atp-dependent helicase
U769_RS08370	COG0537	adenosine 5'-monophosphoramidase activity
U769_RS08420	COG1595	DNA-templated transcription, initiation
U769_RS08490	COG1201	RNA secondary structure unwinding
U769_RS08495	COG2205	protein histidine kinase activity
U769_RS08510	COG4772	TonB-dependent receptor
U769_RS08525	COG2076	Multidrug Resistance protein
U769_RS08530	COG0385	Bile acid
U769_RS08580	COG2200	EAL domain
U769_RS08590	COG3321	synthase
U769_RS08590	COG0604	alcohol dehydrogenase
U769_RS08595	COG0560	Phosphoserine phosphatase
U769_RS08610	COG1176	ABC-type spermidine putrescine transport system, permease component I
U769_RS08640	COG0564	pseudouridine synthase activity
U769_RS08650	COG2894	cell division
U769_RS08660	COG1560	Kdo2-lipid A biosynthetic process
U769_RS08675	COG2853	Lipoprotein
U769_RS08695	COG3162	membrane
U769_RS08700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U769_RS08730	COG1132	(ABC) transporter
U769_RS08740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
U769_RS08765	COG0509	glycine decarboxylation via glycine cleavage system
U769_RS08770	COG0702	epimerase
U769_RS08800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
U769_RS08815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
U769_RS08815	COG0438	transferase activity, transferring glycosyl groups
U769_RS08845	COG1127	ABC transporter
U769_RS08850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
U769_RS08855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
U769_RS08860	COG0727	PFAM Uncharacterised protein family (UPF0153)
U769_RS08865	COG0778	Nitroreductase
U769_RS08885	COG0745	RESPONSE REGULATOR receiver
U769_RS08895	COG2350	Protein conserved in bacteria
U769_RS08905	COG0613	PHP domain protein
U769_RS08910	COG0009	L-threonylcarbamoyladenylate synthase
U769_RS08920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
U769_RS08965	COG1175	transmembrane transport
U769_RS08970	COG0395	ABC-type sugar transport system, permease component
U769_RS08975	COG3842	ATPase activity
U769_RS08985	COG0676	glucose-6-phosphate 1-epimerase activity
U769_RS09030	COG0786	glutamate:sodium symporter activity
U769_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS09060	COG0402	S-adenosylhomocysteine deaminase activity
U769_RS09090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
U769_RS09160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
U769_RS09200	COG0583	DNA-binding transcription factor activity
U769_RS09235	COG0596	Alpha beta hydrolase
U769_RS09240	COG0800	Aldolase
U769_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS09275	COG0583	DNA-binding transcription factor activity
U769_RS09280	COG0251	oxidation-reduction process
U769_RS09300	COG2226	methyltransferase
U769_RS09340	COG0285	dihydrofolate synthase activity
U769_RS09345	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
U769_RS09350	COG1286	toxin biosynthetic process
U769_RS09450	COG0446	pyridine nucleotide-disulphide oxidoreductase
U769_RS09450	COG1902	pentaerythritol trinitrate reductase activity
U769_RS09475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
U769_RS09485	COG3139	Protein of unknown function (DUF1315)
U769_RS09495	COG0308	aminopeptidase N
U769_RS09525	COG0745	RESPONSE REGULATOR receiver
U769_RS09565	COG0714	Associated with various cellular activities
U769_RS09585	COG1335	isochorismatase
U769_RS09595	COG2342	PFAM TM1410 hypothetical-related protein
U769_RS09620	COG0297	glycogen (starch) synthase activity
U769_RS09670	COG3130	regulation of translation
U769_RS09680	COG2027	D-alanyl-D-alanine carboxypeptidase
U769_RS09685	COG3171	Protein conserved in bacteria
U769_RS09690	COG2197	response regulator
U769_RS09695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS09695	COG2205	protein histidine kinase activity
U769_RS09720	COG0004	ammonium transporteR
U769_RS09730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U769_RS09740	COG0625	glutathione transferase activity
U769_RS09745	COG1309	transcriptional regulator
U769_RS09775	COG0521	Mo-molybdopterin cofactor biosynthetic process
U769_RS09800	COG1070	Carbohydrate kinase
U769_RS09820	COG0741	lytic transglycosylase activity
U769_RS09825	COG0488	(ABC) transporter
U769_RS09835	COG0589	response to stress
U769_RS09910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
U769_RS09920	COG1113	amino acid transport
U769_RS09955	COG1477	protein flavinylation
U769_RS09970	COG0584	glycerophosphoryl diester phosphodiesterase
U769_RS09985	COG4591	ABC-type transport system involved in lipoprotein release permease component
U769_RS10005	COG2333	competence protein COMEC
U769_RS10005	COG0658	competence protein
U769_RS10010	COG0811	peptide transport
U769_RS10015	COG0848	biopolymer transport protein
U769_RS10035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U769_RS10045	COG1530	ribonuclease E activity
U769_RS10055	COG0546	phosphoglycolate phosphatase activity
U769_RS10060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
U769_RS10060	COG0616	signal peptide processing
U769_RS10070	COG1399	metal-binding, possibly nucleic acid-binding protein
U769_RS10100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U769_RS10110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
U769_RS10130	COG0084	hydrolase, TatD family'
U769_RS10215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
U769_RS10230	COG0183	Belongs to the thiolase family
U769_RS10240	COG2233	PERMEase
U769_RS10270	COG2814	Major facilitator Superfamily
U769_RS10275	COG1902	pentaerythritol trinitrate reductase activity
U769_RS10280	COG1309	transcriptional regulator
U769_RS10315	COG4160	amino acid transport
U769_RS10320	COG4215	(ABC) transporter
U769_RS10325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS10330	COG1473	amidohydrolase
U769_RS10335	COG0583	DNA-binding transcription factor activity
U769_RS10340	COG0840	transmembrane signaling receptor activity
U769_RS10370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U769_RS10380	COG1120	ATPase activity
U769_RS10410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U769_RS10440	COG3047	cAMP biosynthetic process
U769_RS10440	COG2885	chlorophyll binding
U769_RS10445	COG2197	response regulator
U769_RS10455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U769_RS10460	COG1595	DNA-templated transcription, initiation
U769_RS10475	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS10490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
U769_RS10495	COG1960	acyl-CoA dehydrogenase activity
U769_RS10500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
U769_RS10515	COG1309	transcriptional regulator
U769_RS10530	COG4191	Histidine kinase
U769_RS10545	COG0583	DNA-binding transcription factor activity
U769_RS10555	COG0583	DNA-binding transcription factor activity
U769_RS10565	COG0714	Associated with various cellular activities
U769_RS10610	COG0084	hydrolase, TatD family'
U769_RS10615	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
U769_RS10620	COG2259	Doxx family
U769_RS10635	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
U769_RS10650	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
U769_RS10655	COG4181	ATPase activity
U769_RS10695	COG1764	response to oxidative stress
U769_RS10700	COG1846	Transcriptional regulator
U769_RS10705	COG0583	DNA-binding transcription factor activity
U769_RS10715	COG0583	DNA-binding transcription factor activity
U769_RS10725	COG3214	Protein conserved in bacteria
U769_RS10730	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
U769_RS10740	COG1024	Enoyl-CoA hydratase
U769_RS10750	COG3384	dioxygenase
U769_RS10790	COG2866	Carboxypeptidase
U769_RS10805	COG0436	Aminotransferase
U769_RS10815	COG0386	Belongs to the glutathione peroxidase family
U769_RS10820	COG1846	Transcriptional regulator
U769_RS10825	COG5002	protein histidine kinase activity
U769_RS10825	COG0784	Response regulator, receiver
U769_RS10825	COG2205	protein histidine kinase activity
U769_RS10830	COG2255	four-way junction helicase activity
U769_RS10835	COG1956	GAF domain-containing protein
U769_RS10840	COG0625	glutathione transferase activity
U769_RS10935	COG0625	glutathione transferase activity
U769_RS10940	COG1131	(ABC) transporter
U769_RS10945	COG0842	Transport permease protein
U769_RS10990	COG2188	Transcriptional regulator
U769_RS11000	COG2853	Lipoprotein
U769_RS11010	COG0745	RESPONSE REGULATOR receiver
U769_RS11055	COG0840	transmembrane signaling receptor activity
U769_RS11070	COG3655	Transcriptional regulator
U769_RS11110	COG2116	formate transmembrane transporter activity
U769_RS11115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS11150	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
U769_RS11165	COG1051	belongs to the nudix hydrolase family
U769_RS11175	COG1024	Enoyl-CoA hydratase
U769_RS11175	COG1250	3-hydroxyacyl-CoA dehydrogenase
U769_RS11185	COG2837	iron assimilation
U769_RS11270	COG1238	metal cluster binding
U769_RS11280	COG1295	ribonuclease BN
U769_RS11310	COG0024	Methionine aminopeptidase
U769_RS11435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U769_RS11475	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
U769_RS11475	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
U769_RS11485	COG0542	response to heat
U769_RS11530	COG0789	Transcriptional regulator
U769_RS11540	COG1902	pentaerythritol trinitrate reductase activity
U769_RS11540	COG0446	pyridine nucleotide-disulphide oxidoreductase
U769_RS11545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
U769_RS11550	COG0243	molybdopterin cofactor binding
U769_RS11570	COG1280	lysine exporter protein (LysE YggA)
U769_RS11585	COG0542	response to heat
U769_RS11655	COG1607	acyl-coa hydrolase
U769_RS11660	COG1959	2 iron, 2 sulfur cluster binding
U769_RS11670	COG2819	hydrolase of the alpha beta superfamily
U769_RS11715	COG0583	DNA-binding transcription factor activity
U769_RS11725	COG4106	trans-aconitate 2-methyltransferase activity
U769_RS11745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
U769_RS11750	COG1459	type II secretion system
U769_RS11760	COG2165	general secretion pathway protein
U769_RS11800	COG0720	synthase
U769_RS11805	COG3604	Transcriptional regulator
U769_RS11865	COG0840	transmembrane signaling receptor activity
U769_RS11870	COG2056	Na+-H+ antiporter family
U769_RS11885	COG2226	methyltransferase
U769_RS11980	COG2153	protein acetylation
U769_RS11985	COG2850	peptidyl-arginine hydroxylation
U769_RS12025	COG1278	Cold shock
U769_RS12035	COG0542	response to heat
U769_RS12040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
U769_RS12055	COG0492	ferredoxin-NADP+ reductase activity
U769_RS12070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
U769_RS12085	COG0435	Glutathione S-transferase
U769_RS12090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
U769_RS12095	COG2920	part of a sulfur-relay system
U769_RS12135	COG0583	DNA-binding transcription factor activity
U769_RS12140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U769_RS12145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS12155	COG1960	acyl-CoA dehydrogenase activity
U769_RS12160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS12170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS12185	COG2197	response regulator
U769_RS12190	COG4771	TonB-dependent receptor
U769_RS12235	COG2205	protein histidine kinase activity
U769_RS12235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS12255	COG2249	NAD(P)H dehydrogenase (quinone) activity
U769_RS12270	COG1522	sequence-specific DNA binding
U769_RS12300	COG4191	Histidine kinase
U769_RS12325	COG5001	Diguanylate cyclase
U769_RS12325	COG4251	negative regulation of phosphorylation
U769_RS12325	COG3706	GGDEF domain
U769_RS12325	COG2203	Gaf domain
U769_RS12350	COG0659	secondary active sulfate transmembrane transporter activity
U769_RS12385	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS12395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U769_RS12405	COG0183	Belongs to the thiolase family
U769_RS12410	COG1960	acyl-CoA dehydrogenase activity
U769_RS12460	COG0729	surface antigen
U769_RS12470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
U769_RS12475	COG2267	carboxylic ester hydrolase activity
U769_RS12480	COG0671	phosphoesterase, PA-phosphatase related
U769_RS12480	COG2453	phosphatase
U769_RS12495	COG4589	Belongs to the CDS family
U769_RS12500	COG0667	Aldo Keto reductase
U769_RS12510	COG1115	amino acid carrier protein
U769_RS12520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
U769_RS12540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS12545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS12550	COG1538	Outer membrane efflux protein
U769_RS12610	COG0543	2 iron, 2 sulfur cluster binding
U769_RS12610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U769_RS12615	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
U769_RS12620	COG4638	Rieske (2fe-2S)
U769_RS12635	COG4948	Mandelate Racemase Muconate Lactonizing
U769_RS12645	COG3485	protocatechuate 3,4-dioxygenase
U769_RS12680	COG2807	transmembrane transport
U769_RS12685	COG0590	tRNA wobble adenosine to inosine editing
U769_RS12700	COG2318	DinB family
U769_RS12760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U769_RS12765	COG2863	cytochrome
U769_RS12770	COG3258	Cytochrome c
U769_RS12775	COG0642	Histidine kinase
U769_RS12810	COG0625	glutathione transferase activity
U769_RS12830	COG0583	DNA-binding transcription factor activity
U769_RS12835	COG1595	DNA-templated transcription, initiation
U769_RS12840	COG3712	iron ion homeostasis
U769_RS12910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U769_RS12920	COG2382	esterase
U769_RS12940	COG0583	DNA-binding transcription factor activity
U769_RS12960	COG1760	l-serine dehydratase
U769_RS12965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
U769_RS13000	COG2217	Heavy metal translocating P-type atpase
U769_RS13015	COG0583	DNA-binding transcription factor activity
U769_RS13030	COG1566	PFAM secretion protein HlyD family protein
U769_RS13090	COG1335	isochorismatase
U769_RS13100	COG0583	DNA-binding transcription factor activity
U769_RS13140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U769_RS13145	COG1121	(ABC) transporter
U769_RS13185	COG0657	acetylesterase activity
U769_RS13190	COG4774	siderophore transport
U769_RS13235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS13260	COG0735	belongs to the Fur family
U769_RS13270	COG1304	FMN binding
U769_RS13300	COG4566	intracellular signal transduction
U769_RS13390	COG3829	transcription factor binding
U769_RS13415	COG3829	transcription factor binding
U769_RS13420	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
U769_RS13425	COG0584	glycerophosphoryl diester phosphodiesterase
U769_RS13430	COG2011	ABC-type metal ion transport system permease component
U769_RS13440	COG1464	Belongs to the NlpA lipoprotein family
U769_RS13465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U769_RS13470	COG1070	Carbohydrate kinase
U769_RS13475	COG0246	Mannitol dehydrogenase
U769_RS13490	COG1175	transmembrane transport
U769_RS13505	COG1917	Cupin 2, conserved barrel domain protein
U769_RS13505	COG4977	sequence-specific DNA binding
U769_RS13520	COG1116	anion transmembrane transporter activity
U769_RS13525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
U769_RS13530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U769_RS13550	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS13560	COG3265	gluconokinase activity
U769_RS13565	COG1609	Transcriptional regulator
U769_RS13575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS13580	COG0583	DNA-binding transcription factor activity
U769_RS13600	COG1396	sequence-specific DNA binding
U769_RS13610	COG2175	clavaminate synthase activity
U769_RS13620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
U769_RS13625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
U769_RS13650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U769_RS13650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
U769_RS13660	COG3469	chitinase activity
U769_RS13665	COG2188	Transcriptional regulator
U769_RS13670	COG1053	succinate dehydrogenase
U769_RS13705	COG4772	TonB-dependent receptor
U769_RS13750	COG0431	NADPH-dependent FMN reductase
U769_RS13755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
U769_RS13765	COG0640	Transcriptional regulator
U769_RS13770	COG2207	Transcriptional regulator
U769_RS13775	COG1064	alcohol dehydrogenase
U769_RS13800	COG1309	transcriptional regulator
U769_RS13810	COG0504	CTP synthase activity
U769_RS13845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U769_RS13855	COG1609	Transcriptional regulator
U769_RS13885	COG0252	asparaginase activity
U769_RS13890	COG1115	amino acid carrier protein
U769_RS13935	COG1053	succinate dehydrogenase
U769_RS13945	COG0728	peptidoglycan biosynthetic process
U769_RS14005	COG2258	MOSC domain
U769_RS14035	COG2508	Transcriptional regulator
U769_RS14045	COG4447	cellulose binding
U769_RS14050	COG2409	Drug exporters of the RND superfamily
U769_RS14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS14085	COG2072	flavoprotein involved in K transport
U769_RS14100	COG0531	amino acid
U769_RS14105	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS14110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
U769_RS14125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U769_RS14130	COG3162	membrane
U769_RS14135	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS14170	COG3008	intermembrane lipid transfer
U769_RS14175	COG2995	paraquat-inducible protein a
U769_RS14180	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS14190	COG4948	Mandelate Racemase Muconate Lactonizing
U769_RS14195	COG2271	Major facilitator Superfamily
U769_RS14210	COG3618	amidohydrolase
U769_RS14215	COG2271	Major facilitator Superfamily
U769_RS14250	COG0765	amino acid transport
U769_RS14255	COG0765	amino acid transport
U769_RS14270	COG2084	Dehydrogenase
U769_RS14280	COG2130	NADP-dependent
U769_RS14285	COG1309	transcriptional regulator
U769_RS14330	COG2890	protein-(glutamine-N5) methyltransferase activity
U769_RS14345	COG4191	Histidine kinase
U769_RS14345	COG0784	Response regulator, receiver
U769_RS14375	COG1363	Peptidase, m42
U769_RS14410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
U769_RS14450	COG3568	Endonuclease Exonuclease Phosphatase
U769_RS14455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U769_RS14460	COG0392	lysyltransferase activity
U769_RS14470	COG0366	Alpha amylase catalytic
U769_RS14490	COG1285	pathogenesis
U769_RS14510	COG0058	SHG alpha-glucan phosphorylase activity
U769_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS14530	COG1546	Belongs to the CinA family
U769_RS14560	COG2323	membrane
U769_RS14580	COG3121	Chaperone
U769_RS14590	COG3188	usher protein
U769_RS14595	COG3121	Chaperone
U769_RS14605	COG3969	phosphoadenosine phosphosulfate
U769_RS14615	COG1475	DNA binding
U769_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS14625	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
U769_RS14630	COG0583	DNA-binding transcription factor activity
U769_RS14660	COG2169	Transcriptional regulator
U769_RS14660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U769_RS14675	COG0583	DNA-binding transcription factor activity
U769_RS14680	COG2814	Major facilitator Superfamily
U769_RS14700	COG1984	allophanate hydrolase subunit 2
U769_RS14710	COG0028	Belongs to the TPP enzyme family
U769_RS14720	COG0300	oxidoreductase activity
U769_RS14755	COG2814	Major facilitator Superfamily
U769_RS14765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
U769_RS14785	COG0596	Alpha beta hydrolase
U769_RS14790	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
U769_RS14795	COG0367	asparagine synthase
U769_RS14805	COG1522	sequence-specific DNA binding
U769_RS14820	COG1113	amino acid transport
U769_RS14825	COG2010	Cytochrome c
U769_RS14830	COG2010	Cytochrome c
U769_RS14850	COG5001	Diguanylate cyclase
U769_RS14865	COG2192	nodulation
U769_RS14870	COG2814	Major facilitator Superfamily
U769_RS14900	COG1104	cysteine desulfurase activity
U769_RS14905	COG4172	Belongs to the ABC transporter superfamily
U769_RS14910	COG4239	(ABC) transporter, permease
U769_RS14915	COG4174	ABC transporter (Permease)
U769_RS14925	COG4771	TonB-dependent receptor
U769_RS14940	COG0583	DNA-binding transcription factor activity
U769_RS14960	COG1595	DNA-templated transcription, initiation
U769_RS14975	COG2207	Transcriptional regulator
U769_RS14995	COG0564	pseudouridine synthase activity
U769_RS15005	COG0531	amino acid
U769_RS15010	COG0174	glutamine synthetase
U769_RS15025	COG0028	Belongs to the TPP enzyme family
U769_RS15040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U769_RS15060	COG1522	sequence-specific DNA binding
U769_RS15100	COG1309	transcriptional regulator
U769_RS15105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS15110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS15120	COG3204	pilus organization
U769_RS15125	COG0789	Transcriptional regulator
U769_RS15130	COG1960	acyl-CoA dehydrogenase activity
U769_RS15135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
U769_RS15165	COG0179	Fumarylacetoacetate (FAA) hydrolase
U769_RS15175	COG2271	Major facilitator Superfamily
U769_RS15180	COG3829	transcription factor binding
U769_RS15180	COG3290	protein histidine kinase activity
U769_RS15185	COG2610	gluconate transmembrane transporter activity
U769_RS15190	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS15195	COG2031	fatty acid transporter
U769_RS15210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
U769_RS15215	COG0583	DNA-binding transcription factor activity
U769_RS15220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
U769_RS15225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U769_RS15245	COG2205	protein histidine kinase activity
U769_RS15310	COG3851	Histidine kinase
U769_RS15325	COG2205	protein histidine kinase activity
U769_RS15325	COG0784	Response regulator, receiver
U769_RS15345	COG2194	sulfuric ester hydrolase activity
U769_RS15425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U769_RS15475	COG4626	Terminase
U769_RS15475	COG1802	Transcriptional regulator
U769_RS15565	COG0305	Participates in initiation and elongation during chromosome replication
U769_RS15725	COG0488	(ABC) transporter
U769_RS15740	COG0583	DNA-binding transcription factor activity
U769_RS15745	COG1278	Cold shock
U769_RS15795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
U769_RS15800	COG1609	Transcriptional regulator
U769_RS15805	COG1172	Belongs to the binding-protein-dependent transport system permease family
U769_RS15810	COG1129	ABC transporter
U769_RS15820	COG2204	response regulator
U769_RS15835	COG2010	Cytochrome c
U769_RS15840	COG0753	catalase activity
U769_RS15860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
U769_RS15865	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
U769_RS15870	COG2080	2 iron, 2 sulfur cluster binding
U769_RS15895	COG1944	ATP diphosphatase activity
U769_RS15915	COG4771	TonB-dependent receptor
U769_RS15920	COG0275	rRNA processing
U769_RS15925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
U769_RS15925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U769_RS15940	COG0579	oxidoreductase
U769_RS15970	COG1595	DNA-templated transcription, initiation
U769_RS15975	COG3712	iron ion homeostasis
U769_RS15995	COG2814	Major facilitator Superfamily
U769_RS16045	COG2197	response regulator
U769_RS16070	COG2366	antibiotic biosynthetic process
U769_RS16085	COG0625	glutathione transferase activity
U769_RS16110	COG0417	DNA replication proofreading
U769_RS16155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS16225	COG1309	transcriptional regulator
U769_RS16245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
U769_RS16250	COG0583	DNA-binding transcription factor activity
U769_RS16260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
U769_RS16265	COG2354	Protein conserved in bacteria
U769_RS16270	COG3278	Belongs to the heme-copper respiratory oxidase family
U769_RS16280	COG2239	Acts as a magnesium transporter
U769_RS16295	COG5001	Diguanylate cyclase
U769_RS16295	COG4251	negative regulation of phosphorylation
U769_RS16295	COG3706	GGDEF domain
U769_RS16295	COG2203	Gaf domain
U769_RS16300	COG4977	sequence-specific DNA binding
U769_RS16305	COG3813	Protein conserved in bacteria
U769_RS16370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U769_RS16395	COG0604	alcohol dehydrogenase
U769_RS16400	COG0616	signal peptide processing
U769_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS16425	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS16430	COG0583	DNA-binding transcription factor activity
U769_RS16455	COG1024	Enoyl-CoA hydratase
U769_RS16465	COG0531	amino acid
U769_RS16480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
U769_RS16500	COG1388	LysM domain
U769_RS16500	COG0741	lytic transglycosylase activity
U769_RS16505	COG4166	transmembrane transport
U769_RS16510	COG4166	transmembrane transport
U769_RS16515	COG4174	ABC transporter (Permease)
U769_RS16520	COG4239	(ABC) transporter, permease
U769_RS16525	COG4172	Belongs to the ABC transporter superfamily
U769_RS16535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U769_RS16550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
U769_RS16570	COG0745	RESPONSE REGULATOR receiver
U769_RS16575	COG2205	protein histidine kinase activity
U769_RS16580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U769_RS16630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
U769_RS16650	COG0589	response to stress
U769_RS16670	COG2201	protein-glutamate methylesterase activity
U769_RS16680	COG2223	nitrite transmembrane transporter activity
U769_RS16685	COG0515	serine threonine protein kinase
U769_RS16690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
U769_RS16695	COG2146	nitrite reductase [NAD(P)H] activity
U769_RS16700	COG0243	molybdopterin cofactor binding
U769_RS16720	COG0668	transmembrane transport
U769_RS16760	COG0189	ligase activity
U769_RS16760	COG4067	protein conserved in archaea
U769_RS16800	COG2909	trisaccharide binding
U769_RS16805	COG2909	trisaccharide binding
U769_RS16840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
U769_RS16895	COG0519	Catalyzes the synthesis of GMP from XMP
U769_RS16910	COG0667	Aldo Keto reductase
U769_RS16925	COG0183	Belongs to the thiolase family
U769_RS16945	COG1305	Transglutaminase-like
U769_RS16955	COG2308	Evidence 4 Homologs of previously reported genes of
U769_RS16980	COG1317	bacterial-type flagellum organization
U769_RS17090	COG4789	Type iii secretion
U769_RS17140	COG4790	Type iii secretion
U769_RS17145	COG4794	Type iii secretion
U769_RS17150	COG4791	protein targeting
U769_RS17155	COG4792	protein secretion
U769_RS17235	COG2840	Smr protein MutS2
U769_RS17255	COG2815	serine threonine protein kinase
U769_RS17255	COG0515	serine threonine protein kinase
U769_RS17295	COG2204	response regulator
U769_RS17335	COG0625	glutathione transferase activity
U769_RS17340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
U769_RS17355	COG3135	benzoate transporter
U769_RS17370	COG2130	NADP-dependent
U769_RS17380	COG0840	transmembrane signaling receptor activity
U769_RS17390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
U769_RS17430	COG0745	RESPONSE REGULATOR receiver
U769_RS17435	COG2205	protein histidine kinase activity
U769_RS17460	COG1960	acyl-CoA dehydrogenase activity
U769_RS17470	COG1024	Enoyl-CoA hydratase
U769_RS17475	COG1250	3-hydroxyacyl-CoA dehydrogenase
U769_RS17480	COG2186	Transcriptional regulator
U769_RS17485	COG2807	transmembrane transport
U769_RS17490	COG0628	permease
U769_RS17500	COG0625	glutathione transferase activity
U769_RS17530	COG1022	Amp-dependent synthetase and ligase
U769_RS17560	COG5002	protein histidine kinase activity
U769_RS17560	COG2205	protein histidine kinase activity
U769_RS17560	COG0784	Response regulator, receiver
U769_RS17600	COG1846	Transcriptional regulator
U769_RS17605	COG2080	2 iron, 2 sulfur cluster binding
U769_RS17610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
U769_RS17610	COG2010	Cytochrome c
U769_RS17615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
U769_RS17615	COG2010	Cytochrome c
U769_RS17620	COG2207	Transcriptional regulator
U769_RS17695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
U769_RS17700	COG1053	succinate dehydrogenase
U769_RS17705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
U769_RS17710	COG2009	succinate dehydrogenase
U769_RS17740	COG2084	Dehydrogenase
U769_RS17755	COG3738	Protein conserved in bacteria
U769_RS17780	COG0251	oxidation-reduction process
U769_RS17785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS17790	COG0174	glutamine synthetase
U769_RS17795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS17815	COG0840	transmembrane signaling receptor activity
U769_RS17830	COG3278	Belongs to the heme-copper respiratory oxidase family
U769_RS17845	COG2010	Cytochrome c
U769_RS17850	COG3278	Belongs to the heme-copper respiratory oxidase family
U769_RS17865	COG2010	Cytochrome c
U769_RS17870	COG0348	domain, Protein
U769_RS17880	COG2217	Heavy metal translocating P-type atpase
U769_RS17920	COG2076	Multidrug Resistance protein
U769_RS17950	COG1960	acyl-CoA dehydrogenase activity
U769_RS17965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
U769_RS17990	COG1196	nuclear chromosome segregation
U769_RS18020	COG0402	S-adenosylhomocysteine deaminase activity
U769_RS18030	COG2252	PERMEase
U769_RS18090	COG2233	PERMEase
U769_RS18105	COG1309	transcriptional regulator
U769_RS18115	COG3960	tartronate-semialdehyde synthase activity
U769_RS18120	COG3622	Belongs to the hyi family
U769_RS18125	COG2084	Dehydrogenase
U769_RS18135	COG0469	pyruvate kinase activity
U769_RS18140	COG4413	Urea transporter
U769_RS18145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
U769_RS18160	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
U769_RS18170	COG3192	ethanolamine utilization protein
U769_RS18185	COG0446	pyridine nucleotide-disulphide oxidoreductase
U769_RS18190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
U769_RS18265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U769_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS18280	COG1496	oxidoreductase activity
U769_RS18305	COG0835	chemotaxis
U769_RS18315	COG1192	Involved in chromosome partitioning
U769_RS18320	COG1360	Flagellar Motor Protein
U769_RS18325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
U769_RS18335	COG0643	Histidine kinase
U769_RS18335	COG0784	Response regulator, receiver
U769_RS18335	COG2198	Histidine kinase
U769_RS18365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
U769_RS18370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
U769_RS18390	COG1987	bacterial-type flagellum assembly
U769_RS18430	COG2832	Protein of unknown function (DUF454)
U769_RS18445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS18450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS18460	COG5001	Diguanylate cyclase
U769_RS18460	COG3300	MHYT domain
U769_RS18495	COG0488	(ABC) transporter
U769_RS18550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U769_RS18555	COG0583	DNA-binding transcription factor activity
U769_RS18570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
U769_RS18580	COG3264	Mechanosensitive ion channel
U769_RS18580	COG1196	nuclear chromosome segregation
U769_RS18585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
U769_RS18585	COG0116	Belongs to the methyltransferase superfamily
U769_RS18595	COG0210	DNA helicase
U769_RS18620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
U769_RS18665	COG0438	transferase activity, transferring glycosyl groups
U769_RS18670	COG0463	Glycosyl transferase, family 2
U769_RS18675	COG0438	transferase activity, transferring glycosyl groups
U769_RS18700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
U769_RS18710	COG1450	Type ii and iii secretion system protein
U769_RS18720	COG2207	Transcriptional regulator
U769_RS18725	COG4221	oxidoreductase activity
U769_RS18745	COG1247	-acetyltransferase
U769_RS18765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
U769_RS18780	COG0384	phenazine biosynthesis protein PhzF
U769_RS18810	COG5006	permease, DMT superfamily
U769_RS18825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
U769_RS18840	COG3795	YCII-related domain
U769_RS18850	COG2814	Major facilitator Superfamily
U769_RS18855	COG4941	Belongs to the sigma-70 factor family
U769_RS18865	COG3795	YCII-related domain
U769_RS18875	COG2197	response regulator
U769_RS18880	COG1982	Orn Lys Arg decarboxylase major
U769_RS18885	COG0189	ligase activity
U769_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS18905	COG0765	amino acid transport
U769_RS18910	COG0765	amino acid transport
U769_RS18915	COG1126	abc transporter atp-binding protein
U769_RS18940	COG1902	pentaerythritol trinitrate reductase activity
U769_RS18955	COG1253	flavin adenine dinucleotide binding
U769_RS18960	COG0300	oxidoreductase activity
U769_RS18970	COG0583	DNA-binding transcription factor activity
U769_RS18975	COG3591	Belongs to the peptidase S1B family
U769_RS18975	COG1864	DNA RNA non-specific endonuclease
U769_RS18980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
U769_RS18985	COG4319	ketosteroid isomerase
U769_RS19000	COG4774	siderophore transport
U769_RS19045	COG2814	Major facilitator Superfamily
U769_RS19065	COG0583	DNA-binding transcription factor activity
U769_RS19075	COG0121	glutamine amidotransferase
U769_RS19105	COG3712	iron ion homeostasis
U769_RS19110	COG1595	DNA-templated transcription, initiation
U769_RS19125	COG1230	cation diffusion facilitator family transporter
U769_RS19130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
U769_RS19190	COG1960	acyl-CoA dehydrogenase activity
U769_RS19210	COG0406	alpha-ribazole phosphatase activity
U769_RS19240	COG0778	Nitroreductase
U769_RS19255	COG4206	TonB-dependent receptor
U769_RS19265	COG1802	Transcriptional regulator
U769_RS19275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS19305	COG0477	Major facilitator Superfamily
U769_RS19325	COG0765	amino acid transport
U769_RS19335	COG1126	abc transporter atp-binding protein
U769_RS19345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
U769_RS19350	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS19400	COG4191	Histidine kinase
U769_RS19400	COG0784	Response regulator, receiver
U769_RS19455	COG1289	transmembrane transporter activity
U769_RS19470	COG2207	Transcriptional regulator
U769_RS19490	COG2249	NAD(P)H dehydrogenase (quinone) activity
U769_RS19495	COG2957	Belongs to the agmatine deiminase family
U769_RS19510	COG2957	Belongs to the agmatine deiminase family
U769_RS19515	COG0583	DNA-binding transcription factor activity
U769_RS19525	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
U769_RS19555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
U769_RS19565	COG0318	PFAM AMP-dependent synthetase and ligase
U769_RS19570	COG0367	asparagine synthase
U769_RS19580	COG2211	Major facilitator Superfamily
U769_RS19630	COG1335	isochorismatase
U769_RS19635	COG0583	DNA-binding transcription factor activity
U769_RS19645	COG0791	NLP P60 protein
U769_RS19650	COG0791	NLP P60 protein
U769_RS19660	COG3604	Transcriptional regulator
U769_RS19665	COG2818	Glycosylase
U769_RS19690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
U769_RS19695	COG1960	acyl-CoA dehydrogenase activity
U769_RS19705	COG0625	glutathione transferase activity
U769_RS19725	COG3447	MASE1 domain protein
U769_RS19725	COG5002	protein histidine kinase activity
U769_RS19725	COG5001	Diguanylate cyclase
U769_RS19745	COG4459	periplasmic nitrate reductase
U769_RS19750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
U769_RS19750	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
U769_RS19755	COG3062	negative regulation of establishment of protein localization
U769_RS19765	COG3043	anaerobic respiration
U769_RS19770	COG3005	denitrification pathway
U769_RS19775	COG2951	lytic endotransglycosylase activity
U769_RS19780	COG0861	Integral membrane protein TerC family
U769_RS19785	COG0753	catalase activity
U769_RS19805	COG2977	Belongs to the P-Pant transferase superfamily
U769_RS19810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
U769_RS19825	COG2226	methyltransferase
U769_RS19840	COG2205	protein histidine kinase activity
U769_RS19845	COG0745	RESPONSE REGULATOR receiver
U769_RS19850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
U769_RS19850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U769_RS19855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
U769_RS19860	COG1943	Transposase
U769_RS19885	COG0531	amino acid
U769_RS19915	COG0583	DNA-binding transcription factor activity
U769_RS19920	COG3257	ureidoglycine aminohydrolase activity
U769_RS19935	COG3321	synthase
U769_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS19935	COG0604	alcohol dehydrogenase
U769_RS19940	COG2197	response regulator
U769_RS19980	COG0583	DNA-binding transcription factor activity
U769_RS19985	COG0667	Aldo Keto reductase
U769_RS20010	COG0242	peptide deformylase activity
U769_RS20020	COG2199	diguanylate cyclase activity
U769_RS20025	COG2885	chlorophyll binding
U769_RS20055	COG1132	(ABC) transporter
U769_RS20065	COG4628	conserved protein (DUF2132)
U769_RS20070	COG2133	pyrroloquinoline quinone binding
U769_RS20085	COG2207	Transcriptional regulator
U769_RS20090	COG0477	Major facilitator Superfamily
U769_RS20105	COG2882	bacterial-type flagellum organization
U769_RS20160	COG1516	flagellar protein fliS
U769_RS20165	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
U769_RS20175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
U769_RS20180	COG0438	transferase activity, transferring glycosyl groups
U769_RS20180	COG1216	Glycosyl transferase, family 2
U769_RS20205	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS20210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
U769_RS20255	COG4787	bacterial-type flagellum-dependent cell motility
U769_RS20265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
U769_RS20275	COG1815	bacterial-type flagellum-dependent cell motility
U769_RS20320	COG0326	Molecular chaperone. Has ATPase activity
U769_RS20335	COG3189	MarR family transcriptional regulator
U769_RS20355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
U769_RS20370	COG2212	antiporter activity
U769_RS20375	COG1863	multisubunit Na H antiporter MnhE subunit
U769_RS20380	COG0651	ATP synthesis coupled electron transport
U769_RS20385	COG1006	Multisubunit Na H antiporter MnhC subunit
U769_RS20390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
U769_RS20390	COG2111	Na H antiporter
U769_RS20395	COG3133	Outer membrane lipoprotein
U769_RS20405	COG1929	Belongs to the glycerate kinase type-1 family
U769_RS20410	COG2610	gluconate transmembrane transporter activity
U769_RS20415	COG3835	regulator
U769_RS20425	COG2885	chlorophyll binding
U769_RS20440	COG1199	ATP-dependent helicase activity
U769_RS20480	COG2860	membrane
U769_RS20495	COG0653	protein targeting
U769_RS20500	COG0625	glutathione transferase activity
U769_RS20525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS20530	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS20550	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS20555	COG1960	acyl-CoA dehydrogenase activity
U769_RS20560	COG1024	Enoyl-CoA hydratase
U769_RS20565	COG1960	acyl-CoA dehydrogenase activity
U769_RS20575	COG2814	Major facilitator Superfamily
U769_RS20580	COG2030	dehydratase
U769_RS20590	COG0183	Belongs to the thiolase family
U769_RS20620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
U769_RS20625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
U769_RS20640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
U769_RS20650	COG0425	Belongs to the sulfur carrier protein TusA family
U769_RS20705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
U769_RS20710	COG3188	usher protein
U769_RS20730	COG1051	belongs to the nudix hydrolase family
U769_RS20755	COG2801	Transposase and inactivated derivatives
U769_RS20770	COG0602	queuosine metabolic process
U769_RS20775	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
U769_RS20805	COG0824	Thioesterase
U769_RS20835	COG0783	Belongs to the Dps family
U769_RS20880	COG3118	belongs to the thioredoxin family
U769_RS20915	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
U769_RS20930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
U769_RS20970	COG3122	Protein conserved in bacteria
U769_RS20980	COG3956	TIGRFAM MazG family protein
U769_RS20985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U769_RS21015	COG5002	protein histidine kinase activity
U769_RS21015	COG2205	protein histidine kinase activity
U769_RS21015	COG0784	Response regulator, receiver
U769_RS21020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U769_RS21070	COG3038	cytochrome b561
U769_RS21085	COG4807	Protein conserved in bacteria
U769_RS21095	COG2239	Acts as a magnesium transporter
U769_RS21165	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
U769_RS21260	COG2301	Belongs to the HpcH HpaI aldolase family
U769_RS21270	COG2079	MmgE PrpD family protein
U769_RS21280	COG1960	acyl-CoA dehydrogenase activity
U769_RS21285	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
U769_RS21290	COG0583	DNA-binding transcription factor activity
U769_RS21295	COG0583	DNA-binding transcription factor activity
U769_RS21345	COG1113	amino acid transport
U769_RS21365	COG3321	synthase
U769_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS21365	COG0604	alcohol dehydrogenase
U769_RS21375	COG5001	Diguanylate cyclase
U769_RS21375	COG5002	protein histidine kinase activity
U769_RS21395	COG0271	Belongs to the BolA IbaG family
U769_RS21435	COG0492	ferredoxin-NADP+ reductase activity
U769_RS21440	COG0450	alkyl hydroperoxide reductase
U769_RS21445	COG5001	Diguanylate cyclase
U769_RS21445	COG5002	protein histidine kinase activity
U769_RS21445	COG3447	MASE1 domain protein
U769_RS21475	COG1307	EDD domain protein, DegV family
U769_RS21485	COG1309	transcriptional regulator
U769_RS21490	COG0386	Belongs to the glutathione peroxidase family
U769_RS21510	COG0204	Acyl-transferase
U769_RS21515	COG2885	chlorophyll binding
U769_RS21520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
U769_RS21535	COG2267	carboxylic ester hydrolase activity
U769_RS21650	COG0740	serine-type endopeptidase activity
U769_RS21690	COG3179	chitinase
U769_RS21700	COG1724	mRNA binding
U769_RS21705	COG1598	PFAM Uncharacterised protein family UPF0150
U769_RS21720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
U769_RS21730	COG0305	Participates in initiation and elongation during chromosome replication
U769_RS21735	COG1484	DNA-dependent DNA replication
U769_RS21845	COG0582	viral genome integration into host DNA
U769_RS21945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
U769_RS21960	COG0546	phosphoglycolate phosphatase activity
U769_RS21975	COG3023	N-Acetylmuramoyl-L-alanine amidase
U769_RS21990	COG0656	L-ascorbic acid biosynthetic process
U769_RS22015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U769_RS22025	COG1802	Transcriptional regulator
U769_RS22035	COG0372	Belongs to the citrate synthase family
U769_RS22065	COG1113	amino acid transport
U769_RS22070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U769_RS22100	COG0583	DNA-binding transcription factor activity
U769_RS22105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
U769_RS22115	COG4206	TonB-dependent receptor
U769_RS22125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
U769_RS22190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U769_RS22270	COG3180	Ammonia monooxygenase
U769_RS22280	COG2720	vancomycin resistance protein
U769_RS22295	COG1960	acyl-CoA dehydrogenase activity
U769_RS22300	COG1024	Enoyl-CoA hydratase
U769_RS22320	COG2910	NAD(P)H-binding
U769_RS22325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
U769_RS22395	COG0582	viral genome integration into host DNA
U769_RS22435	COG0596	Alpha beta hydrolase
U769_RS22455	COG1570	exodeoxyribonuclease VII activity
U769_RS22470	COG2894	cell division
U769_RS22480	COG0583	DNA-binding transcription factor activity
U769_RS22530	COG3829	transcription factor binding
U769_RS22695	COG0583	DNA-binding transcription factor activity
U769_RS22710	COG0463	Glycosyl transferase, family 2
U769_RS22715	COG0154	amidase activity
U769_RS22735	COG0583	DNA-binding transcription factor activity
U769_RS22745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
U769_RS22780	COG2831	hemolysin activation secretion protein
U769_RS22925	COG0420	3'-5' exonuclease activity
U769_RS22935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
U769_RS22940	COG1074	ATP-dependent DNA helicase activity
U769_RS22945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
U769_RS22950	COG0095	Lipoate-protein ligase
U769_RS22955	COG0697	spore germination
U769_RS22970	COG0840	transmembrane signaling receptor activity
U769_RS22980	COG0306	phosphate transporter
U769_RS23040	COG4964	Belongs to the GSP D family
U769_RS23060	COG0433	COG0433 Predicted ATPase
U769_RS23095	COG0788	formyltetrahydrofolate deformylase activity
U769_RS23105	COG2925	Exonuclease
U769_RS23135	COG0714	Associated with various cellular activities
U769_RS23165	COG0589	response to stress
U769_RS23175	COG1024	Enoyl-CoA hydratase
U769_RS23185	COG3706	GGDEF domain
U769_RS23205	COG0693	protein deglycase activity
U769_RS23220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U769_RS23235	COG0154	amidase activity
U769_RS23245	COG1473	amidohydrolase
U769_RS23260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
U769_RS23265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
U769_RS23265	COG0426	domain, Protein
U769_RS23285	COG0589	response to stress
U769_RS23300	COG2814	Major facilitator Superfamily
U769_RS23305	COG1902	pentaerythritol trinitrate reductase activity
U769_RS23320	COG1918	ferrous iron import across plasma membrane
U769_RS23335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
U769_RS23375	COG1704	LemA family
U769_RS23400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS23405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS23420	COG3642	lipopolysaccharide core region biosynthetic process
U769_RS23430	COG2205	protein histidine kinase activity
U769_RS23435	COG0745	RESPONSE REGULATOR receiver
U769_RS23470	COG3030	protein affecting phage T7 exclusion by the F plasmid
U769_RS23480	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS23505	COG0668	transmembrane transport
U769_RS23515	COG0745	RESPONSE REGULATOR receiver
U769_RS23530	COG2096	Adenosyltransferase
U769_RS23535	COG0494	nUDIX hydrolase
U769_RS23555	COG0739	heme binding
U769_RS23555	COG0741	lytic transglycosylase activity
U769_RS23555	COG1196	nuclear chromosome segregation
U769_RS23600	COG0772	Belongs to the SEDS family
U769_RS23615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
U769_RS23650	COG3107	peptidoglycan biosynthetic process
U769_RS23665	COG2823	Periplasmic or secreted lipoprotein
U769_RS23670	COG2969	positive regulation of protein catabolic process
U769_RS23675	COG0625	glutathione transferase activity
U769_RS23680	COG2857	Cytochrome c1
U769_RS23685	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
U769_RS23690	COG0723	plastoquinol--plastocyanin reductase activity
U769_RS23705	COG0667	Aldo Keto reductase
U769_RS23710	COG1960	acyl-CoA dehydrogenase activity
U769_RS23725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
U769_RS23735	COG2945	thiolester hydrolase activity
U769_RS23755	COG2951	lytic endotransglycosylase activity
U769_RS23765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
U769_RS23805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
U769_RS23810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
U769_RS23815	COG1127	ABC transporter
U769_RS23825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
U769_RS23840	COG1137	ATPase activity
U769_RS23895	COG0312	modulator of DNA gyrase
U769_RS23905	COG0312	modulator of DNA gyrase
U769_RS23910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
U769_RS23920	COG1530	ribonuclease E activity
U769_RS23935	COG1792	Involved in formation and maintenance of cell shape
U769_RS23940	COG1077	Cell shape determining protein MreB Mrl
U769_RS23960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
U769_RS23965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
U769_RS23970	COG4676	Protein conserved in bacteria
U769_RS23975	COG5445	Predicted secreted protein (DUF2300)
U769_RS23990	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
U769_RS23995	COG4676	Protein conserved in bacteria
U769_RS24000	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
U769_RS24015	COG0747	negative chemotaxis
U769_RS24020	COG0747	negative chemotaxis
U769_RS24035	COG0747	negative chemotaxis
U769_RS24045	COG0747	negative chemotaxis
U769_RS24050	COG0601	transmembrane transport
U769_RS24055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
U769_RS24060	COG0444	Belongs to the ABC transporter superfamily
U769_RS24065	COG4608	Belongs to the ABC transporter superfamily
U769_RS24080	COG1984	allophanate hydrolase subunit 2
U769_RS24100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
U769_RS24105	COG4774	siderophore transport
U769_RS24120	COG2194	sulfuric ester hydrolase activity
U769_RS24130	COG0019	diaminopimelate decarboxylase activity
U769_RS24235	COG1252	NADH dehydrogenase
U769_RS24240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
U769_RS24245	COG2831	hemolysin activation secretion protein
U769_RS24260	COG1192	Involved in chromosome partitioning
U769_RS24385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
U769_RS24400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
U769_RS24425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
U769_RS24680	COG3609	addiction module antidote protein, CC2985 family
U769_RS24700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
U769_RS24765	COG4969	Belongs to the N-Me-Phe pilin family
U769_RS24805	COG1047	Peptidyl-prolyl cis-trans
U769_RS24820	COG0196	riboflavin kinase activity
U769_RS24835	COG3045	CreA protein
U769_RS24860	COG0142	geranyltranstransferase activity
U769_RS24875	COG0545	Peptidyl-prolyl cis-trans isomerase
U769_RS24895	COG1067	ATP-dependent peptidase activity
U769_RS24920	COG4650	regulator
U769_RS24935	COG1690	Belongs to the RtcB family
U769_RS24940	COG3541	Predicted nucleotidyltransferase
U769_RS24960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
U769_RS24985	COG0577	efflux transmembrane transporter activity
U769_RS24985	COG1136	(ABC) transporter
U769_RS24990	COG0577	efflux transmembrane transporter activity
U769_RS24990	COG1136	(ABC) transporter
U769_RS24995	COG0488	(ABC) transporter
U769_RS25015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
U769_RS25020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS25045	COG0523	cobalamin synthesis protein
U769_RS25050	COG2879	small protein
U769_RS25055	COG1966	Carbon starvation protein
U769_RS25125	COG3608	succinylglutamate desuccinylase aspartoacylase
U769_RS25125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
U769_RS25130	COG2010	Cytochrome c
U769_RS25165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
U769_RS25175	COG0833	amino acid
U769_RS25180	COG2119	membrane
U769_RS25195	COG0501	Belongs to the peptidase M48B family
U769_RS25200	COG0840	transmembrane signaling receptor activity
U769_RS25205	COG2135	peptidase activity
U769_RS25210	COG1285	pathogenesis
U769_RS25270	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
U769_RS25325	COG1090	epimerase
U769_RS25330	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
U769_RS25340	COG0789	Transcriptional regulator
U769_RS25360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
U769_RS25415	COG0012	GTP binding
U769_RS25430	COG4974	Belongs to the 'phage' integrase family
U769_RS25440	COG4128	Pfam Zonular occludens toxin
U769_RS25505	COG0288	reversible hydration of carbon dioxide
U769_RS25515	COG0456	acetyltransferase
U769_RS25560	COG1840	ABC-type Fe3 transport system, periplasmic component
U769_RS25565	COG1178	ABC-type Fe3 transport system permease component
U769_RS25570	COG3008	intermembrane lipid transfer
U769_RS25575	COG2995	paraquat-inducible protein a
U769_RS25580	COG2995	paraquat-inducible protein a
U769_RS25620	COG1183	phosphatidylcholine synthase activity
U769_RS25635	COG0028	Belongs to the TPP enzyme family
U769_RS25645	COG3098	single-species biofilm formation
U769_RS25655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
U769_RS25690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
U769_RS25695	COG4558	Periplasmic binding protein
U769_RS25700	COG3720	iron ion transport
U769_RS25705	COG4771	TonB-dependent receptor
U769_RS25730	COG0436	Aminotransferase
U769_RS25740	COG2321	neutral zinc metallopeptidase
U769_RS25750	COG2252	PERMEase
U769_RS25765	COG0436	Aminotransferase
U769_RS25770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U769_RS25785	COG4191	Histidine kinase
U769_RS25885	COG0195	Participates in both transcription termination and antitermination
U769_RS25920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
U769_RS25985	COG0497	DNA recombination
U769_RS26015	COG2186	Transcriptional regulator
U769_RS26020	COG1620	l-lactate permease
U769_RS26070	COG0697	spore germination
U769_RS26090	COG0697	spore germination
U769_RS26095	COG1522	sequence-specific DNA binding
U769_RS26105	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS26125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U769_RS26155	COG0509	glycine decarboxylation via glycine cleavage system
U769_RS26195	COG0531	amino acid
U769_RS26210	COG3276	selenocysteine insertion sequence binding
U769_RS26225	COG2864	formate dehydrogenase
U769_RS26230	COG0437	4 iron, 4 sulfur cluster binding
U769_RS26235	COG3383	formate dehydrogenase (NAD+) activity
U769_RS26235	COG0243	molybdopterin cofactor binding
U769_RS26240	COG3383	formate dehydrogenase (NAD+) activity
U769_RS26240	COG0243	molybdopterin cofactor binding
U769_RS26245	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
U769_RS26250	COG0446	pyridine nucleotide-disulphide oxidoreductase
U769_RS26250	COG1902	pentaerythritol trinitrate reductase activity
U769_RS26275	COG0463	Glycosyl transferase, family 2
U769_RS26285	COG0534	Mate efflux family protein
U769_RS26295	COG1283	sodium-dependent phosphate transmembrane transporter activity
U769_RS26320	COG2162	N-hydroxyarylamine O-acetyltransferase activity
U769_RS26345	COG4221	oxidoreductase activity
U769_RS26350	COG1272	protein, Hemolysin III
U769_RS26385	COG0023	Translation Initiation Factor
U769_RS26470	COG2095	MarC family integral membrane protein
U769_RS26475	COG0683	leucine binding
U769_RS26490	COG0411	ABC transporter
U769_RS26535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
U769_RS26555	COG0443	Heat shock 70 kDa protein
U769_RS26580	COG0789	Transcriptional regulator
U769_RS26585	COG2982	Protein involved in outer membrane biogenesis
U769_RS26590	COG2193	ferroxidase activity
U769_RS26600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
U769_RS26605	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
U769_RS26665	COG3712	iron ion homeostasis
U769_RS26670	COG1595	DNA-templated transcription, initiation
U769_RS26690	COG2814	Major facilitator Superfamily
U769_RS26700	COG0583	DNA-binding transcription factor activity
U769_RS26725	COG4221	oxidoreductase activity
U769_RS26730	COG2423	ornithine cyclodeaminase activity
U769_RS26760	COG0583	DNA-binding transcription factor activity
U769_RS26775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
U769_RS26815	COG0668	transmembrane transport
U769_RS26835	COG5001	Diguanylate cyclase
U769_RS26835	COG3300	MHYT domain
U769_RS26845	COG0305	Participates in initiation and elongation during chromosome replication
U769_RS26875	COG0557	exoribonuclease II activity
U769_RS26905	COG0330	HflC and HflK could
U769_RS26910	COG0330	HflC and HflK could
U769_RS26915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
U769_RS26935	COG0860	N-Acetylmuramoyl-L-alanine amidase
U769_RS26940	COG0802	atpase or kinase
U769_RS26945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
U769_RS26945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
U769_RS26995	COG5001	Diguanylate cyclase
U769_RS26995	COG3300	MHYT domain
U769_RS27000	COG3830	Belongs to the UPF0237 family
U769_RS27000	COG0560	Phosphoserine phosphatase
U769_RS27010	COG1988	membrane-bound metal-dependent
U769_RS27025	COG3577	Aspartyl protease
U769_RS27040	COG3150	esterase
U769_RS27045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
U769_RS27055	COG0494	nUDIX hydrolase
U769_RS27070	COG1538	Outer membrane efflux protein
U769_RS27075	COG2249	NAD(P)H dehydrogenase (quinone) activity
U769_RS27090	COG0045	succinate-CoA ligase (ADP-forming) activity
U769_RS27095	COG1960	acyl-CoA dehydrogenase activity
U769_RS27100	COG1024	Enoyl-CoA hydratase
U769_RS27105	COG0833	amino acid
U769_RS27135	COG0446	pyridine nucleotide-disulphide oxidoreductase
U769_RS27135	COG1902	pentaerythritol trinitrate reductase activity
U769_RS27145	COG1519	Transferase
U769_RS27150	COG0583	DNA-binding transcription factor activity
U769_RS27165	COG0667	Aldo Keto reductase
U769_RS27175	COG1960	acyl-CoA dehydrogenase activity
U769_RS27180	COG1960	acyl-CoA dehydrogenase activity
U769_RS27205	COG1215	transferase activity, transferring glycosyl groups
U769_RS27225	COG0438	transferase activity, transferring glycosyl groups
U769_RS27230	COG2192	nodulation
U769_RS27255	COG0438	transferase activity, transferring glycosyl groups
U769_RS27260	COG0859	PFAM glycosyl transferase family 9
U769_RS27265	COG0859	PFAM glycosyl transferase family 9
U769_RS27300	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
U769_RS27305	COG1960	acyl-CoA dehydrogenase activity
U769_RS27315	COG3264	Mechanosensitive ion channel
U769_RS27315	COG1196	nuclear chromosome segregation
U769_RS27325	COG0730	response to heat
U769_RS27330	COG2873	o-acetylhomoserine
U769_RS27345	COG1192	Involved in chromosome partitioning
U769_RS27350	COG0583	DNA-binding transcription factor activity
U769_RS27355	COG2814	Major facilitator Superfamily
U769_RS27380	COG0493	'glutamate synthase
U769_RS27385	COG0067	glutamate synthase
U769_RS27385	COG0070	glutamate synthase
U769_RS27385	COG0069	glutamate synthase activity
U769_RS27435	COG0281	malic enzyme
U769_RS27455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
U769_RS27565	COG0840	transmembrane signaling receptor activity
U769_RS27575	COG1126	abc transporter atp-binding protein
U769_RS27580	COG0765	amino acid transport
U769_RS27610	COG1051	belongs to the nudix hydrolase family
U769_RS27615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
U769_RS27620	COG0251	oxidation-reduction process
U769_RS27645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U769_RS27665	COG2986	histidine ammonia-lyase
U769_RS27670	COG4175	Glycine betaine
U769_RS27675	COG4176	ABC-type proline glycine betaine transport system permease component
U769_RS27695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
U769_RS27730	COG0402	S-adenosylhomocysteine deaminase activity
U769_RS27780	COG0789	Transcriptional regulator
U769_RS27785	COG1217	gtp-binding protein TYPA
U769_RS27805	COG0668	transmembrane transport
U769_RS27820	COG3852	Histidine kinase
U769_RS27835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
U769_RS27865	COG4942	peptidase
U769_RS27870	COG0793	Belongs to the peptidase S41A family
U769_RS27875	COG2861	carbohydrate metabolic process
U769_RS27935	COG0579	oxidoreductase
U769_RS27945	COG1194	a g-specific adenine glycosylase
U769_RS27955	COG0673	inositol 2-dehydrogenase activity
U769_RS27965	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS28000	COG1846	Transcriptional regulator
U769_RS28010	COG1566	PFAM secretion protein HlyD family protein
U769_RS28015	COG2814	Major facilitator Superfamily
U769_RS28030	COG4695	Portal protein
U769_RS28255	COG3654	unkown
U769_RS28275	COG2801	Transposase and inactivated derivatives
U769_RS28280	COG2963	transposase activity
U769_RS28290	COG1088	dTDP-glucose 4,6-dehydratase activity
U769_RS28295	COG1091	dTDP-4-dehydrorhamnose reductase activity
U769_RS28360	COG1218	3'(2'),5'-bisphosphate nucleotidase
U769_RS28365	COG0494	nUDIX hydrolase
U769_RS28370	COG1011	Hydrolase
U769_RS28375	COG1652	LysM domain
U769_RS28385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
U769_RS28405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
U769_RS28415	COG0824	Thioesterase
U769_RS28420	COG1454	alcohol dehydrogenase
U769_RS28425	COG1960	acyl-CoA dehydrogenase activity
U769_RS28430	COG1024	Enoyl-CoA hydratase
U769_RS28430	COG1250	3-hydroxyacyl-CoA dehydrogenase
U769_RS28440	COG0778	Nitroreductase
U769_RS28465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
U769_RS28470	COG4067	protein conserved in archaea
U769_RS28470	COG0189	ligase activity
U769_RS28495	COG2183	response to ionizing radiation
U769_RS28525	COG0306	phosphate transporter
U769_RS28530	COG1392	Phosphate transport regulator
U769_RS28535	COG3025	triphosphatase activity
U769_RS28540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
U769_RS28570	COG1178	ABC-type Fe3 transport system permease component
U769_RS28580	COG0583	DNA-binding transcription factor activity
U769_RS28595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U769_RS28605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
U769_RS28610	COG0006	proline dipeptidase activity
U769_RS28630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
U769_RS28640	COG0842	Transport permease protein
U769_RS28645	COG0842	Transport permease protein
U769_RS28645	COG1129	ABC transporter
U769_RS28650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
U769_RS28665	COG2271	Major facilitator Superfamily
U769_RS28680	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
U769_RS28680	COG2755	lipolytic protein G-D-S-L family
U769_RS28695	COG0248	Ppx GppA phosphatase
U769_RS28710	COG0586	Pfam SNARE associated Golgi protein
U769_RS28715	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
U769_RS28720	COG2050	protein possibly involved in aromatic compounds catabolism
U769_RS28730	COG0672	)-iron permease
U769_RS28735	COG1280	lysine exporter protein (LysE YggA)
U769_RS28740	COG0861	Integral membrane protein TerC family
U769_RS28750	COG0488	(ABC) transporter
U769_RS28805	COG3275	phosphorelay sensor kinase activity
U769_RS28835	COG0598	Magnesium transport protein CorA
U769_RS28865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
U769_RS28925	COG0432	Pfam Uncharacterised protein family UPF0047
U769_RS28930	COG0004	ammonium transporteR
U769_RS28935	COG0347	Belongs to the P(II) protein family
U769_RS28945	COG0606	chelatase, subunit chli
U769_RS28950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U769_RS28960	COG0583	DNA-binding transcription factor activity
U769_RS28975	COG0210	DNA helicase
U769_RS28980	COG0028	Belongs to the TPP enzyme family
U769_RS28990	COG0427	acetyl-CoA hydrolase
U769_RS29000	COG1396	sequence-specific DNA binding
U769_RS29000	COG1917	Cupin 2, conserved barrel domain protein
U769_RS29010	COG0251	oxidation-reduction process
U769_RS29040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
U769_RS29045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
U769_RS29050	COG2814	Major facilitator Superfamily
U769_RS29055	COG1012	belongs to the aldehyde dehydrogenase family
U769_RS29060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
U769_RS29080	COG0747	negative chemotaxis
U769_RS29095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
U769_RS29135	COG3245	cytochrome
U769_RS29155	COG0708	Exodeoxyribonuclease III
U769_RS29170	COG1561	YicC-like family, N-terminal region
U769_RS29185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
U769_RS29205	COG2169	Transcriptional regulator
U769_RS29215	COG0583	DNA-binding transcription factor activity
U769_RS29220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
U769_RS29255	COG3193	protein, possibly involved in utilization of glycolate and propanediol
U769_RS29260	COG0247	lactate metabolic process
U769_RS29265	COG0277	FAD linked oxidase domain protein
U769_RS29270	COG0277	FAD linked oxidase domain protein
U769_RS29275	COG2186	Transcriptional regulator
U769_RS29305	COG1253	flavin adenine dinucleotide binding
U769_RS29310	COG0739	heme binding
U769_RS29330	COG0573	inorganic phosphate transmembrane transporter activity
U769_RS29370	COG0477	Major facilitator Superfamily
U769_RS29375	COG1607	acyl-coa hydrolase
U769_RS29395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
U769_RS29400	COG4175	Glycine betaine
U769_RS29405	COG4176	ABC-type proline glycine betaine transport system permease component
U769_RS29415	COG1760	l-serine dehydratase
U769_RS29430	COG0583	DNA-binding transcription factor activity
U769_RS29440	COG0657	acetylesterase activity
U769_RS29455	COG3246	L-lysine catabolic process to acetate
U769_RS29510	COG0446	pyridine nucleotide-disulphide oxidoreductase
U769_RS29510	COG1902	pentaerythritol trinitrate reductase activity
U769_RS29515	COG2181	nitrate reductase activity
U769_RS29515	COG0247	lactate metabolic process
U769_RS29520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
U769_RS29535	COG3655	Transcriptional regulator
U769_RS29575	COG1017	nitric oxide dioxygenase activity
U769_RS29575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
U769_RS29660	COG0583	DNA-binding transcription factor activity
U769_RS29670	COG2391	methyltransferase activity
U769_RS29695	COG0511	ligase activity, forming carbon-carbon bonds
U769_RS29695	COG5016	pyruvate
U769_RS29700	COG0439	Biotin carboxylase
U769_RS29705	COG0583	DNA-binding transcription factor activity
U769_RS29720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
U769_RS29725	COG0826	peptidase U32
U769_RS29745	COG0210	DNA helicase
U769_RS29755	COG0427	acetyl-CoA hydrolase
U769_RS29770	COG0438	transferase activity, transferring glycosyl groups
U769_RS29815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
U769_RS29820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
U769_RS29820	COG2755	lipolytic protein G-D-S-L family
U769_RS29860	COG0679	Auxin Efflux Carrier
U769_RS29870	COG2851	Citrate transporter
U769_RS29875	COG0861	Integral membrane protein TerC family
U769_RS29880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
U769_RS29885	COG1690	Belongs to the RtcB family
U769_RS29900	COG0612	Peptidase, M16
U769_RS29920	COG0700	Nucleoside recognition
U769_RS29925	COG1301	dicarboxylic acid transport
U769_RS29950	COG5002	protein histidine kinase activity
U769_RS29955	COG3023	N-Acetylmuramoyl-L-alanine amidase
U769_RS29960	COG2095	MarC family integral membrane protein
U769_RS29985	COG3245	cytochrome
U769_RS30020	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
U769_RS30025	COG0735	belongs to the Fur family
U769_RS30035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
U769_RS30050	COG2011	ABC-type metal ion transport system permease component
U769_RS30080	COG0531	amino acid
U769_RS30090	COG4191	Histidine kinase
U769_RS30120	COG4651	solute:proton antiporter activity
U769_RS30120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
U769_RS30125	COG1607	acyl-coa hydrolase
U769_RS30135	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS30140	COG0174	glutamine synthetase
U769_RS30145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
U769_RS30150	COG1028	Short-chain dehydrogenase reductase Sdr
U769_RS30175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
U769_RS30175	COG4651	solute:proton antiporter activity
U769_RS30180	COG0477	Major facilitator Superfamily
U769_RS30190	COG0523	cobalamin synthesis protein
U769_RS30235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
U769_RS30255	COG2358	TRAP transporter, solute receptor (TAXI family
U769_RS30260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
U769_RS30280	COG1349	DNA-binding transcription factor activity
U769_RS30340	COG1475	DNA binding
U769_RS30345	COG1192	Involved in chromosome partitioning