locus-tag	class	description
CWI25_RS00035	COG2010	Cytochrome c
CWI25_RS00050	COG2818	Glycosylase
CWI25_RS00065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CWI25_RS00080	COG0569	domain protein
CWI25_RS00100	COG1652	LysM domain
CWI25_RS00105	COG0758	DNA mediated transformation
CWI25_RS00135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWI25_RS00155	COG3119	arylsulfatase activity
CWI25_RS00160	COG0583	DNA-binding transcription factor activity
CWI25_RS00195	COG3360	Dodecin
CWI25_RS00290	COG3174	membrane
CWI25_RS00330	COG0367	asparagine synthase
CWI25_RS00355	COG0583	DNA-binding transcription factor activity
CWI25_RS00370	COG1764	response to oxidative stress
CWI25_RS00405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CWI25_RS00410	COG0339	signal peptide processing
CWI25_RS00415	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CWI25_RS00430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWI25_RS00445	COG0515	serine threonine protein kinase
CWI25_RS00445	COG2815	serine threonine protein kinase
CWI25_RS00450	COG0631	protein serine/threonine phosphatase activity
CWI25_RS00465	COG1360	Flagellar Motor Protein
CWI25_RS00595	COG0659	secondary active sulfate transmembrane transporter activity
CWI25_RS00610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWI25_RS00615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWI25_RS00620	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CWI25_RS00660	COG2153	protein acetylation
CWI25_RS00700	COG0583	DNA-binding transcription factor activity
CWI25_RS00725	COG2824	Alkylphosphonate utilization operon protein PhnA
CWI25_RS00755	COG0402	S-adenosylhomocysteine deaminase activity
CWI25_RS00765	COG3845	ABC transporter
CWI25_RS00770	COG4603	Belongs to the binding-protein-dependent transport system permease family
CWI25_RS00775	COG1079	Belongs to the binding-protein-dependent transport system permease family
CWI25_RS00855	COG0583	DNA-binding transcription factor activity
CWI25_RS00860	COG3485	protocatechuate 3,4-dioxygenase
CWI25_RS00865	COG3485	protocatechuate 3,4-dioxygenase
CWI25_RS00875	COG1414	Transcriptional regulator
CWI25_RS00890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS00895	COG0583	DNA-binding transcription factor activity
CWI25_RS00935	COG2233	PERMEase
CWI25_RS00940	COG1309	transcriptional regulator
CWI25_RS00975	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CWI25_RS00990	COG0835	chemotaxis
CWI25_RS00995	COG0643	Histidine kinase
CWI25_RS00995	COG2198	Histidine kinase
CWI25_RS01000	COG0745	RESPONSE REGULATOR receiver
CWI25_RS01010	COG0583	DNA-binding transcription factor activity
CWI25_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS01025	COG1116	anion transmembrane transporter activity
CWI25_RS01030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWI25_RS01035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI25_RS01080	COG2175	clavaminate synthase activity
CWI25_RS01155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWI25_RS01185	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS01190	COG1113	amino acid transport
CWI25_RS01205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI25_RS01210	COG0235	Class ii aldolase
CWI25_RS01215	COG1396	sequence-specific DNA binding
CWI25_RS01220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CWI25_RS01225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWI25_RS01235	COG0477	Major facilitator Superfamily
CWI25_RS01245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWI25_RS01250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWI25_RS01255	COG0583	DNA-binding transcription factor activity
CWI25_RS01275	COG0673	inositol 2-dehydrogenase activity
CWI25_RS01295	COG2271	Major facilitator Superfamily
CWI25_RS01305	COG1309	transcriptional regulator
CWI25_RS01310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWI25_RS01320	COG0477	Major facilitator Superfamily
CWI25_RS01340	COG2239	Acts as a magnesium transporter
CWI25_RS01415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CWI25_RS01460	COG0582	viral genome integration into host DNA
CWI25_RS01495	COG0745	RESPONSE REGULATOR receiver
CWI25_RS01505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWI25_RS01520	COG0583	DNA-binding transcription factor activity
CWI25_RS01525	COG2807	transmembrane transport
CWI25_RS01595	COG0765	amino acid transport
CWI25_RS01610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWI25_RS01615	COG0277	FAD linked oxidase domain protein
CWI25_RS01620	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWI25_RS01630	COG3111	PFAM Bacterial OB fold (BOF) protein
CWI25_RS01640	COG0531	amino acid
CWI25_RS01645	COG2182	Extracellular solute-binding protein
CWI25_RS01650	COG1177	transmembrane transport
CWI25_RS01660	COG3842	ATPase activity
CWI25_RS01670	COG3204	pilus organization
CWI25_RS01675	COG2234	aminopeptidase activity
CWI25_RS01695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWI25_RS01705	COG0702	epimerase
CWI25_RS01735	COG3706	GGDEF domain
CWI25_RS01745	COG0730	response to heat
CWI25_RS01780	COG0584	glycerophosphoryl diester phosphodiesterase
CWI25_RS01800	COG0622	Phosphoesterase
CWI25_RS01805	COG2233	PERMEase
CWI25_RS01820	COG0693	protein deglycase activity
CWI25_RS01860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWI25_RS01870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CWI25_RS01895	COG0429	hydrolase of the alpha beta-hydrolase fold
CWI25_RS01905	COG0742	ribosomal rna small subunit methyltransferase
CWI25_RS01910	COG0612	Peptidase, M16
CWI25_RS01915	COG0612	Peptidase, M16
CWI25_RS01920	COG0552	protein localization to endoplasmic reticulum
CWI25_RS01925	COG2884	Cell division ATP-binding protein ftsE
CWI25_RS01930	COG2177	Part of the ABC transporter FtsEX involved in
CWI25_RS01950	COG2363	Small membrane protein
CWI25_RS01985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWI25_RS02000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWI25_RS02000	COG2813	Specifically methylates the guanine in position
CWI25_RS02010	COG1160	GTP binding
CWI25_RS02015	COG1872	DUF167
CWI25_RS02060	COG0626	cystathionine gamma-synthase activity
CWI25_RS02125	COG0643	Histidine kinase
CWI25_RS02125	COG2198	Histidine kinase
CWI25_RS02125	COG0784	Response regulator, receiver
CWI25_RS02155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWI25_RS02175	COG3038	cytochrome b561
CWI25_RS02205	COG0513	Belongs to the DEAD box helicase family
CWI25_RS02215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CWI25_RS02220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWI25_RS02245	COG1309	transcriptional regulator
CWI25_RS02250	COG0402	S-adenosylhomocysteine deaminase activity
CWI25_RS02255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CWI25_RS02270	COG0493	'glutamate synthase
CWI25_RS02290	COG1953	Uracil, thiamine, allantoin
CWI25_RS02320	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS02325	COG0583	DNA-binding transcription factor activity
CWI25_RS02335	COG0306	phosphate transporter
CWI25_RS02345	COG0330	HflC and HflK could
CWI25_RS02355	COG1289	transmembrane transporter activity
CWI25_RS02360	COG0513	Belongs to the DEAD box helicase family
CWI25_RS02370	COG0189	ligase activity
CWI25_RS02370	COG4067	protein conserved in archaea
CWI25_RS02375	COG0477	Major facilitator Superfamily
CWI25_RS02380	COG0542	response to heat
CWI25_RS02390	COG0204	Acyl-transferase
CWI25_RS02400	COG0745	RESPONSE REGULATOR receiver
CWI25_RS02405	COG2205	protein histidine kinase activity
CWI25_RS02410	COG4452	Inner membrane protein CreD
CWI25_RS02445	COG4774	siderophore transport
CWI25_RS02450	COG3712	iron ion homeostasis
CWI25_RS02455	COG1595	DNA-templated transcription, initiation
CWI25_RS02460	COG0625	glutathione transferase activity
CWI25_RS02470	COG1309	transcriptional regulator
CWI25_RS02475	COG1953	Uracil, thiamine, allantoin
CWI25_RS02495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWI25_RS02530	COG2005	Transcriptional regulator
CWI25_RS02530	COG3585	molybdate ion transport
CWI25_RS02535	COG5544	Lipoprotein
CWI25_RS02540	COG1040	competence protein
CWI25_RS02560	COG0511	ligase activity, forming carbon-carbon bonds
CWI25_RS02575	COG1984	allophanate hydrolase subunit 2
CWI25_RS02595	COG1073	alpha beta
CWI25_RS02595	COG2226	methyltransferase
CWI25_RS02615	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS02620	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS02630	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS02685	COG4396	Host-nuclease inhibitor protein Gam
CWI25_RS02775	COG4383	Mu-like prophage protein gp29
CWI25_RS02780	COG2369	cell adhesion
CWI25_RS02785	COG5005	Phage virion morphogenesis
CWI25_RS02805	COG4397	Mu-like prophage major head subunit gpT
CWI25_RS02900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWI25_RS02900	COG1648	precorrin-2 dehydrogenase activity
CWI25_RS02985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWI25_RS02990	COG0583	DNA-binding transcription factor activity
CWI25_RS02995	COG2258	MOSC domain
CWI25_RS03005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWI25_RS03030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS03040	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CWI25_RS03095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWI25_RS03100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWI25_RS03110	COG3622	Belongs to the hyi family
CWI25_RS03115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CWI25_RS03155	COG2081	HI0933 family
CWI25_RS03160	COG1451	nucleotide metabolic process
CWI25_RS03165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWI25_RS03170	COG3152	Membrane
CWI25_RS03175	COG1917	Cupin 2, conserved barrel domain protein
CWI25_RS03175	COG4977	sequence-specific DNA binding
CWI25_RS03180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWI25_RS03245	COG3344	reverse transcriptase
CWI25_RS03285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CWI25_RS03305	COG2719	SpoVR family
CWI25_RS03315	COG2766	serine protein kinase
CWI25_RS03365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CWI25_RS03380	COG2197	response regulator
CWI25_RS03390	COG3842	ATPase activity
CWI25_RS03400	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWI25_RS03410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWI25_RS03435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWI25_RS03520	COG3179	chitinase
CWI25_RS03555	COG1765	OsmC-like protein
CWI25_RS03570	COG0537	adenosine 5'-monophosphoramidase activity
CWI25_RS03595	COG1981	membrane
CWI25_RS03625	COG0739	heme binding
CWI25_RS03790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWI25_RS03915	COG2814	Major facilitator Superfamily
CWI25_RS03940	COG1021	2,3-dihydroxybenzoate-AMP ligase
CWI25_RS03950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWI25_RS03950	COG2226	methyltransferase
CWI25_RS03950	COG3433	isochorismatase activity
CWI25_RS03955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWI25_RS03955	COG3433	isochorismatase activity
CWI25_RS03955	COG2226	methyltransferase
CWI25_RS03965	COG1132	(ABC) transporter
CWI25_RS03965	COG2375	cellular response to nickel ion
CWI25_RS04050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS04065	COG2706	6-phosphogluconolactonase activity
CWI25_RS04085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWI25_RS04090	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS04100	COG4191	Histidine kinase
CWI25_RS04105	COG4566	intracellular signal transduction
CWI25_RS04110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS04115	COG0765	amino acid transport
CWI25_RS04120	COG0765	amino acid transport
CWI25_RS04140	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS04145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI25_RS04150	COG2271	Major facilitator Superfamily
CWI25_RS04200	COG2226	methyltransferase
CWI25_RS04210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWI25_RS04225	COG0251	oxidation-reduction process
CWI25_RS04235	COG0693	protein deglycase activity
CWI25_RS04240	COG0492	ferredoxin-NADP+ reductase activity
CWI25_RS04245	COG1959	2 iron, 2 sulfur cluster binding
CWI25_RS04275	COG0154	amidase activity
CWI25_RS04285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI25_RS04290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI25_RS04295	COG4592	Periplasmic binding protein
CWI25_RS04300	COG1120	ATPase activity
CWI25_RS04310	COG1629	transport
CWI25_RS04310	COG4774	siderophore transport
CWI25_RS04315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWI25_RS04320	COG4991	sh3 domain protein
CWI25_RS04325	COG1063	alcohol dehydrogenase
CWI25_RS04335	COG0022	dehydrogenase e1 component
CWI25_RS04340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWI25_RS04345	COG3199	ATP-NAD kinase
CWI25_RS04355	COG3284	Transcriptional regulator
CWI25_RS04380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS04415	COG2814	Major facilitator Superfamily
CWI25_RS04420	COG1846	Transcriptional regulator
CWI25_RS04430	COG3278	Belongs to the heme-copper respiratory oxidase family
CWI25_RS04435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWI25_RS04445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWI25_RS04460	COG3971	2-oxopent-4-enoate hydratase activity
CWI25_RS04465	COG2271	Major facilitator Superfamily
CWI25_RS04475	COG3384	dioxygenase
CWI25_RS04480	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS04520	COG1611	Belongs to the LOG family
CWI25_RS04565	COG0583	DNA-binding transcription factor activity
CWI25_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS04590	COG1063	alcohol dehydrogenase
CWI25_RS04595	COG2271	Major facilitator Superfamily
CWI25_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS04635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CWI25_RS04650	COG3121	Chaperone
CWI25_RS04655	COG3188	usher protein
CWI25_RS04675	COG2197	response regulator
CWI25_RS04715	COG0531	amino acid
CWI25_RS04735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWI25_RS04745	COG3047	cAMP biosynthetic process
CWI25_RS04775	COG3118	belongs to the thioredoxin family
CWI25_RS04780	COG2264	protein methyltransferase activity
CWI25_RS04800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWI25_RS04800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWI25_RS04825	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CWI25_RS04830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CWI25_RS04840	COG3577	Aspartyl protease
CWI25_RS04865	COG0142	geranyltranstransferase activity
CWI25_RS04875	COG4948	Mandelate Racemase Muconate Lactonizing
CWI25_RS04895	COG1131	(ABC) transporter
CWI25_RS04900	COG5002	protein histidine kinase activity
CWI25_RS04920	COG0745	RESPONSE REGULATOR receiver
CWI25_RS04930	COG3228	Belongs to the MtfA family
CWI25_RS04935	COG0586	Pfam SNARE associated Golgi protein
CWI25_RS04950	COG0456	acetyltransferase
CWI25_RS04960	COG4303	Ethanolamine ammonia lyase large subunit
CWI25_RS04965	COG0531	amino acid
CWI25_RS04975	COG3284	Transcriptional regulator
CWI25_RS04980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWI25_RS04995	COG0702	epimerase
CWI25_RS05015	COG1346	cytolysis
CWI25_RS05025	COG0586	Pfam SNARE associated Golgi protein
CWI25_RS05065	COG0768	penicillin binding
CWI25_RS05070	COG0772	Belongs to the SEDS family
CWI25_RS05075	COG2951	lytic endotransglycosylase activity
CWI25_RS05085	COG1686	Belongs to the peptidase S11 family
CWI25_RS05115	COG2951	lytic endotransglycosylase activity
CWI25_RS05150	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CWI25_RS05160	COG4535	Mg2 and Co2 transporter CorC
CWI25_RS05170	COG1702	phosphate starvation-inducible protein PhoH
CWI25_RS05200	COG0351	phosphomethylpyrimidine kinase
CWI25_RS05205	COG0784	Response regulator, receiver
CWI25_RS05205	COG2198	Histidine kinase
CWI25_RS05205	COG2205	protein histidine kinase activity
CWI25_RS05215	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS05225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWI25_RS05265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWI25_RS05275	COG1643	Atp-dependent helicase
CWI25_RS05320	COG3416	Protein conserved in bacteria
CWI25_RS05330	COG0513	Belongs to the DEAD box helicase family
CWI25_RS05345	COG2197	response regulator
CWI25_RS05350	COG2199	diguanylate cyclase activity
CWI25_RS05350	COG2202	Pas domain
CWI25_RS05350	COG2200	EAL domain
CWI25_RS05355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS05355	COG2205	protein histidine kinase activity
CWI25_RS05375	COG1946	Acyl-CoA thioesterase
CWI25_RS05395	COG4521	taurine ABC transporter
CWI25_RS05405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWI25_RS05410	COG2175	clavaminate synthase activity
CWI25_RS05415	COG1297	OPT oligopeptide transporter protein
CWI25_RS05420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWI25_RS05435	COG1271	oxidase subunit
CWI25_RS05440	COG1294	oxidase, subunit
CWI25_RS05450	COG2207	Transcriptional regulator
CWI25_RS05460	COG0183	Belongs to the thiolase family
CWI25_RS05465	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS05500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CWI25_RS05525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CWI25_RS05535	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWI25_RS05540	COG0303	'Molybdopterin
CWI25_RS05545	COG0826	peptidase U32
CWI25_RS05550	COG0826	peptidase U32
CWI25_RS05555	COG3154	lipid carrier protein
CWI25_RS05605	COG4772	TonB-dependent receptor
CWI25_RS05610	COG3712	iron ion homeostasis
CWI25_RS05615	COG1595	DNA-templated transcription, initiation
CWI25_RS05625	COG0697	spore germination
CWI25_RS05635	COG0583	DNA-binding transcription factor activity
CWI25_RS05655	COG1566	PFAM secretion protein HlyD family protein
CWI25_RS05710	COG0300	oxidoreductase activity
CWI25_RS05715	COG2226	methyltransferase
CWI25_RS05730	COG2197	response regulator
CWI25_RS05735	COG3850	Histidine kinase
CWI25_RS05745	COG2223	nitrite transmembrane transporter activity
CWI25_RS05750	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CWI25_RS05755	COG1140	nitrate reductase beta subunit
CWI25_RS05760	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CWI25_RS05765	COG2181	nitrate reductase activity
CWI25_RS05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWI25_RS05785	COG4771	TonB-dependent receptor
CWI25_RS05790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS05820	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS05830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS05895	COG0583	DNA-binding transcription factor activity
CWI25_RS05910	COG0640	Transcriptional regulator
CWI25_RS05935	COG0471	metal ion transport
CWI25_RS05935	COG0490	domain, Protein
CWI25_RS05940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CWI25_RS05945	COG4120	Belongs to the binding-protein-dependent transport system permease family
CWI25_RS05995	COG0795	lipopolysaccharide-transporting ATPase activity
CWI25_RS06000	COG0795	lipopolysaccharide-transporting ATPase activity
CWI25_RS06010	COG2200	EAL domain
CWI25_RS06055	COG1862	Preprotein translocase
CWI25_RS06070	COG3134	Outer membrane lipoprotein
CWI25_RS06085	COG1045	serine acetyltransferase
CWI25_RS06175	COG0436	Aminotransferase
CWI25_RS06190	COG0667	Aldo Keto reductase
CWI25_RS06230	COG0739	heme binding
CWI25_RS06240	COG2847	Copper chaperone PCu(A)C
CWI25_RS06250	COG1335	isochorismatase
CWI25_RS06265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWI25_RS06275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWI25_RS06280	COG0583	DNA-binding transcription factor activity
CWI25_RS06330	COG2132	Multicopper oxidase
CWI25_RS06335	COG0590	tRNA wobble adenosine to inosine editing
CWI25_RS06380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWI25_RS06380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI25_RS06385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWI25_RS06390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CWI25_RS06395	COG2188	Transcriptional regulator
CWI25_RS06435	COG0477	Major facilitator Superfamily
CWI25_RS06440	COG4536	flavin adenine dinucleotide binding
CWI25_RS06450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWI25_RS06475	COG1607	acyl-coa hydrolase
CWI25_RS06495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CWI25_RS06520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWI25_RS06560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWI25_RS06570	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS06615	COG2197	response regulator
CWI25_RS06620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CWI25_RS06640	COG0477	Major facilitator Superfamily
CWI25_RS06675	COG5001	Diguanylate cyclase
CWI25_RS06675	COG4251	negative regulation of phosphorylation
CWI25_RS06675	COG3706	GGDEF domain
CWI25_RS06675	COG2203	Gaf domain
CWI25_RS06710	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CWI25_RS06710	COG3064	Membrane
CWI25_RS06710	COG1073	alpha beta
CWI25_RS06725	COG2885	chlorophyll binding
CWI25_RS06740	COG0789	Transcriptional regulator
CWI25_RS06760	COG1214	PFAM Peptidase M22, glycoprotease
CWI25_RS06770	COG1801	Protein of unknown function DUF72
CWI25_RS06775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CWI25_RS06800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS06845	COG2166	iron-sulfur cluster assembly
CWI25_RS06860	COG1280	lysine exporter protein (LysE YggA)
CWI25_RS06865	COG1393	Belongs to the ArsC family
CWI25_RS06885	COG0025	NhaP-type Na H and K H
CWI25_RS06890	COG0436	Aminotransferase
CWI25_RS06900	COG0024	Methionine aminopeptidase
CWI25_RS06980	COG1115	amino acid carrier protein
CWI25_RS07030	COG2391	methyltransferase activity
CWI25_RS07035	COG0583	DNA-binding transcription factor activity
CWI25_RS07040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CWI25_RS07045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CWI25_RS07100	COG1546	Belongs to the CinA family
CWI25_RS07120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CWI25_RS07125	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CWI25_RS07130	COG3530	Putative quorum-sensing-regulated virulence factor
CWI25_RS07145	COG1177	transmembrane transport
CWI25_RS07150	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWI25_RS07160	COG3148	PFAM DTW domain containing protein
CWI25_RS07180	COG0069	glutamate synthase activity
CWI25_RS07205	COG0531	amino acid
CWI25_RS07210	COG2169	Transcriptional regulator
CWI25_RS07210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWI25_RS07215	COG0477	Major facilitator Superfamily
CWI25_RS07225	COG0583	DNA-binding transcription factor activity
CWI25_RS07230	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS07235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWI25_RS07240	COG1024	Enoyl-CoA hydratase
CWI25_RS07245	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWI25_RS07250	COG0183	Belongs to the thiolase family
CWI25_RS07260	COG0583	DNA-binding transcription factor activity
CWI25_RS07300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWI25_RS07345	COG2814	Major facilitator Superfamily
CWI25_RS07385	COG0583	DNA-binding transcription factor activity
CWI25_RS07395	COG0084	hydrolase, TatD family'
CWI25_RS07400	COG1609	Transcriptional regulator
CWI25_RS07410	COG1105	Belongs to the carbohydrate kinase PfkB family
CWI25_RS07415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWI25_RS07415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWI25_RS07415	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CWI25_RS07530	COG3842	ATPase activity
CWI25_RS07550	COG0243	molybdopterin cofactor binding
CWI25_RS07555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CWI25_RS07560	COG2223	nitrite transmembrane transporter activity
CWI25_RS07575	COG0450	alkyl hydroperoxide reductase
CWI25_RS07605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS07640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWI25_RS07645	COG2264	protein methyltransferase activity
CWI25_RS07655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWI25_RS07710	COG0489	protein tyrosine kinase activity
CWI25_RS07760	COG0791	NLP P60 protein
CWI25_RS07780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWI25_RS07785	COG0668	transmembrane transport
CWI25_RS07790	COG0477	Major facilitator Superfamily
CWI25_RS07795	COG0513	Belongs to the DEAD box helicase family
CWI25_RS07815	COG5002	protein histidine kinase activity
CWI25_RS07815	COG2205	protein histidine kinase activity
CWI25_RS07815	COG0784	Response regulator, receiver
CWI25_RS07820	COG1363	Peptidase, m42
CWI25_RS07825	COG0189	ligase activity
CWI25_RS07825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWI25_RS07830	COG0367	asparagine synthase
CWI25_RS07860	COG0183	Belongs to the thiolase family
CWI25_RS07880	COG0450	alkyl hydroperoxide reductase
CWI25_RS07885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI25_RS07890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWI25_RS07900	COG0431	NADPH-dependent FMN reductase
CWI25_RS07905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI25_RS07915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWI25_RS07940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CWI25_RS07965	COG0583	DNA-binding transcription factor activity
CWI25_RS07970	COG1380	Effector of murein hydrolase LrgA
CWI25_RS07975	COG1346	cytolysis
CWI25_RS07995	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS08000	COG1024	Enoyl-CoA hydratase
CWI25_RS08010	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CWI25_RS08055	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWI25_RS08095	COG1629	transport
CWI25_RS08160	COG0583	DNA-binding transcription factor activity
CWI25_RS08235	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CWI25_RS08240	COG3639	organic phosphonate transmembrane transporter activity
CWI25_RS08245	COG2188	Transcriptional regulator
CWI25_RS08250	COG3624	Phosphonate C-P lyase system protein PhnG
CWI25_RS08260	COG3626	phosphonate metabolism
CWI25_RS08265	COG3627	carbon phosphorus lyase activity
CWI25_RS08270	COG4107	phosphonate C-P lyase system protein PhnK
CWI25_RS08275	COG4778	phosphonate C-P lyase system protein PhnL
CWI25_RS08280	COG3454	Phosphonate metabolism
CWI25_RS08290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWI25_RS08390	COG1566	PFAM secretion protein HlyD family protein
CWI25_RS08400	COG0697	spore germination
CWI25_RS08425	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CWI25_RS08445	COG0784	Response regulator, receiver
CWI25_RS08445	COG0835	chemotaxis
CWI25_RS08460	COG0745	RESPONSE REGULATOR receiver
CWI25_RS08470	COG0514	ATP-dependent DNA helicase (RecQ)
CWI25_RS08475	COG4251	negative regulation of phosphorylation
CWI25_RS08475	COG5001	Diguanylate cyclase
CWI25_RS08475	COG3706	GGDEF domain
CWI25_RS08475	COG2203	Gaf domain
CWI25_RS08500	COG1752	Esterase of the alpha-beta hydrolase superfamily
CWI25_RS08540	COG2124	cytochrome p450
CWI25_RS08545	COG4221	oxidoreductase activity
CWI25_RS08560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWI25_RS08590	COG0583	DNA-binding transcription factor activity
CWI25_RS08625	COG3639	organic phosphonate transmembrane transporter activity
CWI25_RS08635	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CWI25_RS08640	COG2084	Dehydrogenase
CWI25_RS08655	COG0589	response to stress
CWI25_RS08695	COG2814	Major facilitator Superfamily
CWI25_RS08700	COG2030	dehydratase
CWI25_RS08705	COG2267	carboxylic ester hydrolase activity
CWI25_RS08710	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS08715	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS08725	COG1643	Atp-dependent helicase
CWI25_RS08735	COG0537	adenosine 5'-monophosphoramidase activity
CWI25_RS08790	COG1595	DNA-templated transcription, initiation
CWI25_RS08865	COG1201	RNA secondary structure unwinding
CWI25_RS08870	COG2205	protein histidine kinase activity
CWI25_RS08885	COG4772	TonB-dependent receptor
CWI25_RS08900	COG2076	Multidrug Resistance protein
CWI25_RS08905	COG0385	Bile acid
CWI25_RS08965	COG0604	alcohol dehydrogenase
CWI25_RS08965	COG3321	synthase
CWI25_RS08970	COG0560	Phosphoserine phosphatase
CWI25_RS08985	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWI25_RS09015	COG0564	pseudouridine synthase activity
CWI25_RS09025	COG2894	cell division
CWI25_RS09035	COG1560	Kdo2-lipid A biosynthetic process
CWI25_RS09050	COG2853	Lipoprotein
CWI25_RS09070	COG3162	membrane
CWI25_RS09075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWI25_RS09105	COG1132	(ABC) transporter
CWI25_RS09140	COG0509	glycine decarboxylation via glycine cleavage system
CWI25_RS09145	COG0702	epimerase
CWI25_RS09170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI25_RS09185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CWI25_RS09185	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS09215	COG1127	ABC transporter
CWI25_RS09220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWI25_RS09225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWI25_RS09230	COG0727	PFAM Uncharacterised protein family (UPF0153)
CWI25_RS09235	COG0778	Nitroreductase
CWI25_RS09255	COG0745	RESPONSE REGULATOR receiver
CWI25_RS09265	COG2350	Protein conserved in bacteria
CWI25_RS09275	COG0613	PHP domain protein
CWI25_RS09280	COG0009	L-threonylcarbamoyladenylate synthase
CWI25_RS09285	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CWI25_RS09290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CWI25_RS09340	COG1175	transmembrane transport
CWI25_RS09345	COG0395	ABC-type sugar transport system, permease component
CWI25_RS09350	COG3842	ATPase activity
CWI25_RS09365	COG0676	glucose-6-phosphate 1-epimerase activity
CWI25_RS09415	COG0786	glutamate:sodium symporter activity
CWI25_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS09445	COG0402	S-adenosylhomocysteine deaminase activity
CWI25_RS09475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CWI25_RS09520	COG1086	Polysaccharide biosynthesis protein
CWI25_RS09545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWI25_RS09585	COG0583	DNA-binding transcription factor activity
CWI25_RS09620	COG0596	Alpha beta hydrolase
CWI25_RS09625	COG0800	Aldolase
CWI25_RS09640	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS09660	COG0583	DNA-binding transcription factor activity
CWI25_RS09665	COG0251	oxidation-reduction process
CWI25_RS09685	COG2226	methyltransferase
CWI25_RS09725	COG0285	dihydrofolate synthase activity
CWI25_RS09730	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CWI25_RS09735	COG1286	toxin biosynthetic process
CWI25_RS09835	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI25_RS09835	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS09860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CWI25_RS09870	COG3139	Protein of unknown function (DUF1315)
CWI25_RS09880	COG0308	aminopeptidase N
CWI25_RS09915	COG0745	RESPONSE REGULATOR receiver
CWI25_RS09950	COG0714	Associated with various cellular activities
CWI25_RS09965	COG2342	PFAM TM1410 hypothetical-related protein
CWI25_RS09990	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS10040	COG3130	regulation of translation
CWI25_RS10055	COG2027	D-alanyl-D-alanine carboxypeptidase
CWI25_RS10060	COG3171	Protein conserved in bacteria
CWI25_RS10065	COG2197	response regulator
CWI25_RS10070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS10070	COG2205	protein histidine kinase activity
CWI25_RS10100	COG0004	ammonium transporteR
CWI25_RS10110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWI25_RS10120	COG0625	glutathione transferase activity
CWI25_RS10125	COG1309	transcriptional regulator
CWI25_RS10190	COG0582	viral genome integration into host DNA
CWI25_RS10210	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWI25_RS10230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWI25_RS10235	COG1070	Carbohydrate kinase
CWI25_RS10255	COG0741	lytic transglycosylase activity
CWI25_RS10260	COG0488	(ABC) transporter
CWI25_RS10270	COG0589	response to stress
CWI25_RS10350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWI25_RS10360	COG1113	amino acid transport
CWI25_RS10395	COG1477	protein flavinylation
CWI25_RS10410	COG0584	glycerophosphoryl diester phosphodiesterase
CWI25_RS10425	COG4591	ABC-type transport system involved in lipoprotein release permease component
CWI25_RS10445	COG0658	competence protein
CWI25_RS10445	COG2333	competence protein COMEC
CWI25_RS10450	COG0811	peptide transport
CWI25_RS10455	COG0848	biopolymer transport protein
CWI25_RS10475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWI25_RS10485	COG1530	ribonuclease E activity
CWI25_RS10505	COG0616	signal peptide processing
CWI25_RS10505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CWI25_RS10515	COG1399	metal-binding, possibly nucleic acid-binding protein
CWI25_RS10545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWI25_RS10555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWI25_RS10575	COG0084	hydrolase, TatD family'
CWI25_RS10660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWI25_RS10675	COG0183	Belongs to the thiolase family
CWI25_RS10690	COG2233	PERMEase
CWI25_RS10715	COG2814	Major facilitator Superfamily
CWI25_RS10720	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS10725	COG1309	transcriptional regulator
CWI25_RS10760	COG4160	amino acid transport
CWI25_RS10765	COG4215	(ABC) transporter
CWI25_RS10770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS10775	COG1473	amidohydrolase
CWI25_RS10780	COG0583	DNA-binding transcription factor activity
CWI25_RS10785	COG0840	transmembrane signaling receptor activity
CWI25_RS10815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI25_RS10825	COG1120	ATPase activity
CWI25_RS10855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWI25_RS10885	COG2885	chlorophyll binding
CWI25_RS10885	COG3047	cAMP biosynthetic process
CWI25_RS10890	COG2197	response regulator
CWI25_RS10900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWI25_RS10905	COG1595	DNA-templated transcription, initiation
CWI25_RS10920	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS10935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWI25_RS10940	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS10945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWI25_RS10960	COG1309	transcriptional regulator
CWI25_RS10990	COG0583	DNA-binding transcription factor activity
CWI25_RS11000	COG0583	DNA-binding transcription factor activity
CWI25_RS11010	COG0714	Associated with various cellular activities
CWI25_RS11055	COG0084	hydrolase, TatD family'
CWI25_RS11060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CWI25_RS11065	COG2259	Doxx family
CWI25_RS11080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CWI25_RS11095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CWI25_RS11100	COG4181	ATPase activity
CWI25_RS11140	COG1764	response to oxidative stress
CWI25_RS11145	COG1846	Transcriptional regulator
CWI25_RS11150	COG0583	DNA-binding transcription factor activity
CWI25_RS11160	COG0583	DNA-binding transcription factor activity
CWI25_RS11170	COG3214	Protein conserved in bacteria
CWI25_RS11175	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CWI25_RS11185	COG1024	Enoyl-CoA hydratase
CWI25_RS11195	COG3384	dioxygenase
CWI25_RS11235	COG2866	Carboxypeptidase
CWI25_RS11250	COG0436	Aminotransferase
CWI25_RS11260	COG0386	Belongs to the glutathione peroxidase family
CWI25_RS11265	COG1846	Transcriptional regulator
CWI25_RS11270	COG0784	Response regulator, receiver
CWI25_RS11270	COG5002	protein histidine kinase activity
CWI25_RS11270	COG2205	protein histidine kinase activity
CWI25_RS11275	COG2255	four-way junction helicase activity
CWI25_RS11280	COG1956	GAF domain-containing protein
CWI25_RS11285	COG0625	glutathione transferase activity
CWI25_RS11305	COG0582	viral genome integration into host DNA
CWI25_RS11310	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS11335	COG1396	sequence-specific DNA binding
CWI25_RS11340	COG0583	DNA-binding transcription factor activity
CWI25_RS11380	COG2132	Multicopper oxidase
CWI25_RS11385	COG0745	RESPONSE REGULATOR receiver
CWI25_RS11390	COG5002	protein histidine kinase activity
CWI25_RS11400	COG0640	Transcriptional regulator
CWI25_RS11415	COG0798	PFAM Bile acid sodium symporter
CWI25_RS11425	COG1695	Transcriptional regulator
CWI25_RS11505	COG2003	Belongs to the UPF0758 family
CWI25_RS11560	COG3311	Transcriptional regulator
CWI25_RS11565	COG1569	PIN domain
CWI25_RS11570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWI25_RS11720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWI25_RS11730	COG0789	Transcriptional regulator
CWI25_RS11745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWI25_RS11750	COG0629	single-stranded DNA binding
CWI25_RS11880	COG0625	glutathione transferase activity
CWI25_RS11885	COG1131	(ABC) transporter
CWI25_RS11890	COG0842	Transport permease protein
CWI25_RS11935	COG2188	Transcriptional regulator
CWI25_RS11945	COG2853	Lipoprotein
CWI25_RS11955	COG0745	RESPONSE REGULATOR receiver
CWI25_RS11995	COG5434	Belongs to the glycosyl hydrolase 28 family
CWI25_RS12010	COG0840	transmembrane signaling receptor activity
CWI25_RS12025	COG3655	Transcriptional regulator
CWI25_RS12065	COG2116	formate transmembrane transporter activity
CWI25_RS12070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS12110	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CWI25_RS12125	COG1051	belongs to the nudix hydrolase family
CWI25_RS12135	COG1024	Enoyl-CoA hydratase
CWI25_RS12135	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWI25_RS12145	COG2837	iron assimilation
CWI25_RS12230	COG1238	metal cluster binding
CWI25_RS12240	COG1295	ribonuclease BN
CWI25_RS12270	COG0024	Methionine aminopeptidase
CWI25_RS12355	COG2826	transposase and inactivated derivatives, IS30 family
CWI25_RS12425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CWI25_RS12425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CWI25_RS12435	COG0542	response to heat
CWI25_RS12480	COG0789	Transcriptional regulator
CWI25_RS12490	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS12490	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI25_RS12495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CWI25_RS12500	COG0243	molybdopterin cofactor binding
CWI25_RS12540	COG0542	response to heat
CWI25_RS12615	COG1607	acyl-coa hydrolase
CWI25_RS12620	COG1959	2 iron, 2 sulfur cluster binding
CWI25_RS12630	COG2819	hydrolase of the alpha beta superfamily
CWI25_RS12665	COG1802	Transcriptional regulator
CWI25_RS12670	COG3938	Belongs to the proline racemase family
CWI25_RS12675	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS12680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS12685	COG3938	Belongs to the proline racemase family
CWI25_RS12690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI25_RS12695	COG0765	amino acid transport
CWI25_RS12700	COG0765	amino acid transport
CWI25_RS12705	COG1126	abc transporter atp-binding protein
CWI25_RS12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS12725	COG0583	DNA-binding transcription factor activity
CWI25_RS12735	COG4106	trans-aconitate 2-methyltransferase activity
CWI25_RS12755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWI25_RS12760	COG1459	type II secretion system
CWI25_RS12810	COG0720	synthase
CWI25_RS12815	COG3604	Transcriptional regulator
CWI25_RS12875	COG0840	transmembrane signaling receptor activity
CWI25_RS12880	COG2056	Na+-H+ antiporter family
CWI25_RS12895	COG2226	methyltransferase
CWI25_RS12995	COG2153	protein acetylation
CWI25_RS13000	COG2850	peptidyl-arginine hydroxylation
CWI25_RS13040	COG1278	Cold shock
CWI25_RS13050	COG0542	response to heat
CWI25_RS13055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWI25_RS13070	COG0492	ferredoxin-NADP+ reductase activity
CWI25_RS13085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWI25_RS13100	COG0435	Glutathione S-transferase
CWI25_RS13105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CWI25_RS13110	COG2920	part of a sulfur-relay system
CWI25_RS13150	COG0583	DNA-binding transcription factor activity
CWI25_RS13155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWI25_RS13160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI25_RS13170	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS13175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI25_RS13185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI25_RS13200	COG2197	response regulator
CWI25_RS13205	COG4771	TonB-dependent receptor
CWI25_RS13255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS13255	COG2205	protein histidine kinase activity
CWI25_RS13335	COG0419	ATPase involved in DNA repair
CWI25_RS13340	COG1674	ftsk spoiiie
CWI25_RS13350	COG3723	Recombinational DNA repair protein, rece pathway
CWI25_RS13370	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CWI25_RS13435	COG5484	DNA packaging
CWI25_RS13435	COG3728	DNA packaging
CWI25_RS13510	COG1196	nuclear chromosome segregation
CWI25_RS13510	COG1196	nuclear chromosome segregation
CWI25_RS13575	COG3179	chitinase
CWI25_RS13605	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWI25_RS13620	COG1522	sequence-specific DNA binding
CWI25_RS13650	COG4191	Histidine kinase
CWI25_RS13675	COG4251	negative regulation of phosphorylation
CWI25_RS13675	COG2203	Gaf domain
CWI25_RS13675	COG3706	GGDEF domain
CWI25_RS13675	COG5001	Diguanylate cyclase
CWI25_RS13700	COG0659	secondary active sulfate transmembrane transporter activity
CWI25_RS13735	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS13745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWI25_RS13755	COG0183	Belongs to the thiolase family
CWI25_RS13760	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS13810	COG0729	surface antigen
CWI25_RS13820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWI25_RS13825	COG2267	carboxylic ester hydrolase activity
CWI25_RS13830	COG0671	phosphoesterase, PA-phosphatase related
CWI25_RS13830	COG2453	phosphatase
CWI25_RS13845	COG4589	Belongs to the CDS family
CWI25_RS13850	COG0667	Aldo Keto reductase
CWI25_RS13860	COG1115	amino acid carrier protein
CWI25_RS13870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWI25_RS13900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS13905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS13910	COG1538	Outer membrane efflux protein
CWI25_RS13970	COG0543	2 iron, 2 sulfur cluster binding
CWI25_RS13970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWI25_RS13975	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CWI25_RS13980	COG4638	Rieske (2fe-2S)
CWI25_RS14005	COG4948	Mandelate Racemase Muconate Lactonizing
CWI25_RS14015	COG3485	protocatechuate 3,4-dioxygenase
CWI25_RS14025	COG2831	hemolysin activation secretion protein
CWI25_RS14030	COG3210	domain, Protein
CWI25_RS14030	COG3210	domain, Protein
CWI25_RS14075	COG2807	transmembrane transport
CWI25_RS14080	COG0590	tRNA wobble adenosine to inosine editing
CWI25_RS14095	COG2318	DinB family
CWI25_RS14160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWI25_RS14165	COG2863	cytochrome
CWI25_RS14170	COG3258	Cytochrome c
CWI25_RS14180	COG0642	Histidine kinase
CWI25_RS14215	COG0625	glutathione transferase activity
CWI25_RS14235	COG0583	DNA-binding transcription factor activity
CWI25_RS14240	COG1595	DNA-templated transcription, initiation
CWI25_RS14245	COG3712	iron ion homeostasis
CWI25_RS14350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWI25_RS14360	COG2382	esterase
CWI25_RS14380	COG0583	DNA-binding transcription factor activity
CWI25_RS14405	COG1760	l-serine dehydratase
CWI25_RS14410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CWI25_RS14445	COG2217	Heavy metal translocating P-type atpase
CWI25_RS14460	COG0583	DNA-binding transcription factor activity
CWI25_RS14480	COG1566	PFAM secretion protein HlyD family protein
CWI25_RS14515	COG5566	PFAM Mor transcription activator
CWI25_RS14575	COG0488	(ABC) transporter
CWI25_RS14650	COG0640	Transcriptional regulator
CWI25_RS14660	COG4373	Mu-like prophage FluMu protein gp28
CWI25_RS14665	COG4383	Mu-like prophage protein gp29
CWI25_RS14690	COG4397	Mu-like prophage major head subunit gpT
CWI25_RS14840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWI25_RS14850	COG2814	Major facilitator Superfamily
CWI25_RS14885	COG0300	oxidoreductase activity
CWI25_RS14895	COG0028	Belongs to the TPP enzyme family
CWI25_RS14905	COG1984	allophanate hydrolase subunit 2
CWI25_RS14925	COG2814	Major facilitator Superfamily
CWI25_RS14930	COG0583	DNA-binding transcription factor activity
CWI25_RS14950	COG2169	Transcriptional regulator
CWI25_RS14950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWI25_RS14985	COG0583	DNA-binding transcription factor activity
CWI25_RS14990	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CWI25_RS14995	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS15000	COG1475	DNA binding
CWI25_RS15010	COG3969	phosphoadenosine phosphosulfate
CWI25_RS15020	COG3121	Chaperone
CWI25_RS15035	COG3121	Chaperone
CWI25_RS15055	COG2323	membrane
CWI25_RS15085	COG1546	Belongs to the CinA family
CWI25_RS15090	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS15105	COG0058	SHG alpha-glucan phosphorylase activity
CWI25_RS15130	COG1285	pathogenesis
CWI25_RS15150	COG0366	Alpha amylase catalytic
CWI25_RS15160	COG0392	lysyltransferase activity
CWI25_RS15165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWI25_RS15170	COG3568	Endonuclease Exonuclease Phosphatase
CWI25_RS15215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWI25_RS15255	COG1363	Peptidase, m42
CWI25_RS15285	COG4191	Histidine kinase
CWI25_RS15285	COG0784	Response regulator, receiver
CWI25_RS15300	COG2890	protein-(glutamine-N5) methyltransferase activity
CWI25_RS15355	COG1309	transcriptional regulator
CWI25_RS15360	COG2130	NADP-dependent
CWI25_RS15370	COG2084	Dehydrogenase
CWI25_RS15375	COG2203	Gaf domain
CWI25_RS15375	COG3706	GGDEF domain
CWI25_RS15375	COG4251	negative regulation of phosphorylation
CWI25_RS15375	COG5001	Diguanylate cyclase
CWI25_RS15385	COG0765	amino acid transport
CWI25_RS15390	COG0765	amino acid transport
CWI25_RS15425	COG2271	Major facilitator Superfamily
CWI25_RS15430	COG3618	amidohydrolase
CWI25_RS15445	COG2271	Major facilitator Superfamily
CWI25_RS15450	COG4948	Mandelate Racemase Muconate Lactonizing
CWI25_RS15460	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS15465	COG2995	paraquat-inducible protein a
CWI25_RS15470	COG3008	intermembrane lipid transfer
CWI25_RS15500	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS15510	COG3162	membrane
CWI25_RS15515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWI25_RS15530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWI25_RS15535	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS15540	COG0531	amino acid
CWI25_RS15555	COG2072	flavoprotein involved in K transport
CWI25_RS15570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS15590	COG2409	Drug exporters of the RND superfamily
CWI25_RS15595	COG4447	cellulose binding
CWI25_RS15605	COG2508	Transcriptional regulator
CWI25_RS15660	COG2258	MOSC domain
CWI25_RS15725	COG0728	peptidoglycan biosynthetic process
CWI25_RS15735	COG1053	succinate dehydrogenase
CWI25_RS15780	COG1115	amino acid carrier protein
CWI25_RS15785	COG0252	asparaginase activity
CWI25_RS15820	COG1609	Transcriptional regulator
CWI25_RS15830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWI25_RS15865	COG2329	Antibiotic biosynthesis monooxygenase
CWI25_RS15875	COG1309	transcriptional regulator
CWI25_RS15900	COG1064	alcohol dehydrogenase
CWI25_RS15905	COG2207	Transcriptional regulator
CWI25_RS15910	COG0640	Transcriptional regulator
CWI25_RS15920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWI25_RS15925	COG0431	NADPH-dependent FMN reductase
CWI25_RS15970	COG4772	TonB-dependent receptor
CWI25_RS16010	COG1053	succinate dehydrogenase
CWI25_RS16015	COG2188	Transcriptional regulator
CWI25_RS16020	COG3469	chitinase activity
CWI25_RS16030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWI25_RS16030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWI25_RS16055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWI25_RS16060	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWI25_RS16070	COG2175	clavaminate synthase activity
CWI25_RS16080	COG1396	sequence-specific DNA binding
CWI25_RS16100	COG0583	DNA-binding transcription factor activity
CWI25_RS16105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS16135	COG3960	tartronate-semialdehyde synthase activity
CWI25_RS16140	COG3622	Belongs to the hyi family
CWI25_RS16145	COG2084	Dehydrogenase
CWI25_RS16155	COG0469	pyruvate kinase activity
CWI25_RS16160	COG4413	Urea transporter
CWI25_RS16165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWI25_RS16180	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CWI25_RS16190	COG3192	ethanolamine utilization protein
CWI25_RS16205	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI25_RS16210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CWI25_RS16285	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CWI25_RS16295	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS16300	COG1496	oxidoreductase activity
CWI25_RS16310	COG2378	regulation of single-species biofilm formation
CWI25_RS16325	COG2832	Protein of unknown function (DUF454)
CWI25_RS16340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS16345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS16390	COG0488	(ABC) transporter
CWI25_RS16420	COG3846	protein secretion by the type IV secretion system
CWI25_RS16435	COG3451	type IV secretory pathway VirB4
CWI25_RS16445	COG3838	Conjugal transfer protein Trbc
CWI25_RS16450	COG4962	Type ii secretion system protein e
CWI25_RS16480	COG2076	Multidrug Resistance protein
CWI25_RS16490	COG0583	DNA-binding transcription factor activity
CWI25_RS16525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWI25_RS16530	COG1127	ABC transporter
CWI25_RS16555	COG4959	Type IV secretory pathway protease TraF
CWI25_RS16615	COG5489	Protein of unknown function (DUF736)
CWI25_RS16630	COG1475	DNA binding
CWI25_RS17130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWI25_RS17140	COG0583	DNA-binding transcription factor activity
CWI25_RS17155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CWI25_RS17170	COG1196	nuclear chromosome segregation
CWI25_RS17170	COG3264	Mechanosensitive ion channel
CWI25_RS17175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWI25_RS17175	COG0116	Belongs to the methyltransferase superfamily
CWI25_RS17185	COG0210	DNA helicase
CWI25_RS17210	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWI25_RS17260	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS17265	COG0463	Glycosyl transferase, family 2
CWI25_RS17270	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS17295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWI25_RS17305	COG1450	Type ii and iii secretion system protein
CWI25_RS17315	COG2207	Transcriptional regulator
CWI25_RS17320	COG0300	oxidoreductase activity
CWI25_RS17330	COG1247	-acetyltransferase
CWI25_RS17350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWI25_RS17385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS17390	COG4221	oxidoreductase activity
CWI25_RS17400	COG2020	methyltransferase activity
CWI25_RS17405	COG3634	alkyl hydroperoxide reductase activity
CWI25_RS17410	COG1309	transcriptional regulator
CWI25_RS17420	COG0384	phenazine biosynthesis protein PhzF
CWI25_RS17450	COG5006	permease, DMT superfamily
CWI25_RS17465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWI25_RS17480	COG3795	YCII-related domain
CWI25_RS17490	COG2814	Major facilitator Superfamily
CWI25_RS17495	COG4941	Belongs to the sigma-70 factor family
CWI25_RS17505	COG3795	YCII-related domain
CWI25_RS17515	COG2197	response regulator
CWI25_RS17520	COG1982	Orn Lys Arg decarboxylase major
CWI25_RS17525	COG0189	ligase activity
CWI25_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS17545	COG0765	amino acid transport
CWI25_RS17550	COG0765	amino acid transport
CWI25_RS17555	COG1126	abc transporter atp-binding protein
CWI25_RS17585	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS17605	COG1253	flavin adenine dinucleotide binding
CWI25_RS17610	COG0300	oxidoreductase activity
CWI25_RS17620	COG0583	DNA-binding transcription factor activity
CWI25_RS17625	COG3591	Belongs to the peptidase S1B family
CWI25_RS17625	COG1864	DNA RNA non-specific endonuclease
CWI25_RS17630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWI25_RS17635	COG4319	ketosteroid isomerase
CWI25_RS17650	COG4774	siderophore transport
CWI25_RS17700	COG0477	Major facilitator Superfamily
CWI25_RS17720	COG0583	DNA-binding transcription factor activity
CWI25_RS17730	COG0121	glutamine amidotransferase
CWI25_RS17760	COG3712	iron ion homeostasis
CWI25_RS17765	COG1595	DNA-templated transcription, initiation
CWI25_RS17780	COG1230	cation diffusion facilitator family transporter
CWI25_RS17785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWI25_RS17845	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS17865	COG0406	alpha-ribazole phosphatase activity
CWI25_RS17895	COG0778	Nitroreductase
CWI25_RS17910	COG4206	TonB-dependent receptor
CWI25_RS17920	COG1802	Transcriptional regulator
CWI25_RS17930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS17965	COG0477	Major facilitator Superfamily
CWI25_RS17985	COG0765	amino acid transport
CWI25_RS17995	COG1126	abc transporter atp-binding protein
CWI25_RS18005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI25_RS18010	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS18070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWI25_RS18075	COG1518	maintenance of DNA repeat elements
CWI25_RS18090	COG1857	crispr-associated protein
CWI25_RS18115	COG0784	Response regulator, receiver
CWI25_RS18115	COG4191	Histidine kinase
CWI25_RS18170	COG1289	transmembrane transporter activity
CWI25_RS18185	COG2207	Transcriptional regulator
CWI25_RS18205	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWI25_RS18210	COG2957	Belongs to the agmatine deiminase family
CWI25_RS18225	COG2957	Belongs to the agmatine deiminase family
CWI25_RS18230	COG0583	DNA-binding transcription factor activity
CWI25_RS18240	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CWI25_RS18265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWI25_RS18275	COG0318	PFAM AMP-dependent synthetase and ligase
CWI25_RS18280	COG0367	asparagine synthase
CWI25_RS18290	COG2211	Major facilitator Superfamily
CWI25_RS18340	COG1335	isochorismatase
CWI25_RS18345	COG0583	DNA-binding transcription factor activity
CWI25_RS18355	COG0791	NLP P60 protein
CWI25_RS18360	COG0791	NLP P60 protein
CWI25_RS18370	COG3829	transcription factor binding
CWI25_RS18385	COG2818	Glycosylase
CWI25_RS18410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWI25_RS18415	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS18425	COG0625	glutathione transferase activity
CWI25_RS18450	COG5001	Diguanylate cyclase
CWI25_RS18450	COG3447	MASE1 domain protein
CWI25_RS18450	COG5002	protein histidine kinase activity
CWI25_RS18470	COG4459	periplasmic nitrate reductase
CWI25_RS18475	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWI25_RS18475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWI25_RS18480	COG3062	negative regulation of establishment of protein localization
CWI25_RS18490	COG3043	anaerobic respiration
CWI25_RS18495	COG3005	denitrification pathway
CWI25_RS18500	COG2951	lytic endotransglycosylase activity
CWI25_RS18505	COG0861	Integral membrane protein TerC family
CWI25_RS18510	COG0753	catalase activity
CWI25_RS18530	COG2977	Belongs to the P-Pant transferase superfamily
CWI25_RS18535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CWI25_RS18550	COG2226	methyltransferase
CWI25_RS18565	COG2205	protein histidine kinase activity
CWI25_RS18570	COG0745	RESPONSE REGULATOR receiver
CWI25_RS18575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI25_RS18575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWI25_RS18580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI25_RS18630	COG0583	DNA-binding transcription factor activity
CWI25_RS18635	COG3257	ureidoglycine aminohydrolase activity
CWI25_RS18650	COG3321	synthase
CWI25_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS18650	COG0604	alcohol dehydrogenase
CWI25_RS18655	COG2197	response regulator
CWI25_RS18695	COG0583	DNA-binding transcription factor activity
CWI25_RS18700	COG0667	Aldo Keto reductase
CWI25_RS18730	COG0242	peptide deformylase activity
CWI25_RS18740	COG2199	diguanylate cyclase activity
CWI25_RS18745	COG2885	chlorophyll binding
CWI25_RS18775	COG1132	(ABC) transporter
CWI25_RS18790	COG4628	conserved protein (DUF2132)
CWI25_RS18795	COG2133	pyrroloquinoline quinone binding
CWI25_RS18810	COG2207	Transcriptional regulator
CWI25_RS18815	COG0477	Major facilitator Superfamily
CWI25_RS18830	COG2882	bacterial-type flagellum organization
CWI25_RS18885	COG1516	flagellar protein fliS
CWI25_RS18890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CWI25_RS18900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CWI25_RS18905	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS18905	COG1216	Glycosyl transferase, family 2
CWI25_RS18930	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS18935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWI25_RS18980	COG4787	bacterial-type flagellum-dependent cell motility
CWI25_RS19000	COG1815	bacterial-type flagellum-dependent cell motility
CWI25_RS19050	COG0326	Molecular chaperone. Has ATPase activity
CWI25_RS19065	COG3189	MarR family transcriptional regulator
CWI25_RS19085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWI25_RS19100	COG2212	antiporter activity
CWI25_RS19105	COG1863	multisubunit Na H antiporter MnhE subunit
CWI25_RS19110	COG0651	ATP synthesis coupled electron transport
CWI25_RS19115	COG1006	Multisubunit Na H antiporter MnhC subunit
CWI25_RS19120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CWI25_RS19120	COG2111	Na H antiporter
CWI25_RS19130	COG3133	Outer membrane lipoprotein
CWI25_RS19140	COG1929	Belongs to the glycerate kinase type-1 family
CWI25_RS19145	COG2610	gluconate transmembrane transporter activity
CWI25_RS19150	COG3835	regulator
CWI25_RS19160	COG2885	chlorophyll binding
CWI25_RS19175	COG1199	ATP-dependent helicase activity
CWI25_RS19215	COG2860	membrane
CWI25_RS19230	COG0653	protein targeting
CWI25_RS19235	COG0625	glutathione transferase activity
CWI25_RS19260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS19265	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS19290	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS19295	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS19300	COG1024	Enoyl-CoA hydratase
CWI25_RS19305	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS19315	COG2814	Major facilitator Superfamily
CWI25_RS19320	COG2030	dehydratase
CWI25_RS19360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CWI25_RS19365	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CWI25_RS19380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CWI25_RS19390	COG0425	Belongs to the sulfur carrier protein TusA family
CWI25_RS19445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWI25_RS19450	COG3188	usher protein
CWI25_RS19475	COG1051	belongs to the nudix hydrolase family
CWI25_RS19590	COG4974	Belongs to the 'phage' integrase family
CWI25_RS19605	COG2135	peptidase activity
CWI25_RS19690	COG1074	ATP-dependent DNA helicase activity
CWI25_RS19810	COG3609	addiction module antidote protein, CC2985 family
CWI25_RS19840	COG5290	Psort location Cytoplasmic, score
CWI25_RS19870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CWI25_RS19890	COG0602	queuosine metabolic process
CWI25_RS19895	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CWI25_RS19925	COG0824	Thioesterase
CWI25_RS19955	COG0783	Belongs to the Dps family
CWI25_RS20000	COG3118	belongs to the thioredoxin family
CWI25_RS20035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWI25_RS20055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWI25_RS20095	COG3122	Protein conserved in bacteria
CWI25_RS20105	COG3956	TIGRFAM MazG family protein
CWI25_RS20110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWI25_RS20140	COG5002	protein histidine kinase activity
CWI25_RS20140	COG2205	protein histidine kinase activity
CWI25_RS20140	COG0784	Response regulator, receiver
CWI25_RS20145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWI25_RS20195	COG3038	cytochrome b561
CWI25_RS20215	COG4807	Protein conserved in bacteria
CWI25_RS20225	COG2239	Acts as a magnesium transporter
CWI25_RS20295	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CWI25_RS20390	COG2301	Belongs to the HpcH HpaI aldolase family
CWI25_RS20400	COG2079	MmgE PrpD family protein
CWI25_RS20410	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS20415	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CWI25_RS20420	COG0583	DNA-binding transcription factor activity
CWI25_RS20425	COG0583	DNA-binding transcription factor activity
CWI25_RS20485	COG1113	amino acid transport
CWI25_RS20505	COG0604	alcohol dehydrogenase
CWI25_RS20505	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS20505	COG3321	synthase
CWI25_RS20515	COG5001	Diguanylate cyclase
CWI25_RS20515	COG5002	protein histidine kinase activity
CWI25_RS20535	COG0271	Belongs to the BolA IbaG family
CWI25_RS20575	COG0492	ferredoxin-NADP+ reductase activity
CWI25_RS20580	COG0450	alkyl hydroperoxide reductase
CWI25_RS20615	COG1307	EDD domain protein, DegV family
CWI25_RS20625	COG1309	transcriptional regulator
CWI25_RS20630	COG0386	Belongs to the glutathione peroxidase family
CWI25_RS20655	COG0204	Acyl-transferase
CWI25_RS20660	COG2885	chlorophyll binding
CWI25_RS20665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWI25_RS20680	COG2267	carboxylic ester hydrolase activity
CWI25_RS20765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWI25_RS20780	COG0546	phosphoglycolate phosphatase activity
CWI25_RS20795	COG3023	N-Acetylmuramoyl-L-alanine amidase
CWI25_RS20810	COG0656	L-ascorbic acid biosynthetic process
CWI25_RS20835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWI25_RS20845	COG1802	Transcriptional regulator
CWI25_RS20855	COG0372	Belongs to the citrate synthase family
CWI25_RS20870	COG2079	MmgE PrpD family protein
CWI25_RS20885	COG1113	amino acid transport
CWI25_RS20890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWI25_RS20920	COG0583	DNA-binding transcription factor activity
CWI25_RS20925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWI25_RS20935	COG4206	TonB-dependent receptor
CWI25_RS20945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWI25_RS21010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWI25_RS21090	COG3180	Ammonia monooxygenase
CWI25_RS21100	COG2720	vancomycin resistance protein
CWI25_RS21115	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS21120	COG1024	Enoyl-CoA hydratase
CWI25_RS21140	COG2910	NAD(P)H-binding
CWI25_RS21145	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CWI25_RS21225	COG4974	Belongs to the 'phage' integrase family
CWI25_RS21235	COG4128	Pfam Zonular occludens toxin
CWI25_RS21335	COG0583	DNA-binding transcription factor activity
CWI25_RS21350	COG0463	Glycosyl transferase, family 2
CWI25_RS21360	COG0154	amidase activity
CWI25_RS21380	COG0583	DNA-binding transcription factor activity
CWI25_RS21475	COG3851	Histidine kinase
CWI25_RS21490	COG0784	Response regulator, receiver
CWI25_RS21490	COG2205	protein histidine kinase activity
CWI25_RS21510	COG2194	sulfuric ester hydrolase activity
CWI25_RS21555	COG0488	(ABC) transporter
CWI25_RS21570	COG0583	DNA-binding transcription factor activity
CWI25_RS21575	COG1278	Cold shock
CWI25_RS21625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWI25_RS21630	COG1609	Transcriptional regulator
CWI25_RS21635	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWI25_RS21640	COG1129	ABC transporter
CWI25_RS21650	COG2204	response regulator
CWI25_RS21670	COG2010	Cytochrome c
CWI25_RS21675	COG0753	catalase activity
CWI25_RS21690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWI25_RS21695	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWI25_RS21700	COG2080	2 iron, 2 sulfur cluster binding
CWI25_RS21725	COG1944	ATP diphosphatase activity
CWI25_RS21745	COG4771	TonB-dependent receptor
CWI25_RS21750	COG0275	rRNA processing
CWI25_RS21755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI25_RS21755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWI25_RS21770	COG0579	oxidoreductase
CWI25_RS21805	COG1595	DNA-templated transcription, initiation
CWI25_RS21810	COG3712	iron ion homeostasis
CWI25_RS21830	COG2814	Major facilitator Superfamily
CWI25_RS21880	COG2197	response regulator
CWI25_RS21905	COG2366	antibiotic biosynthetic process
CWI25_RS21920	COG0625	glutathione transferase activity
CWI25_RS21940	COG0417	DNA replication proofreading
CWI25_RS21985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS22055	COG1309	transcriptional regulator
CWI25_RS22075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CWI25_RS22080	COG0583	DNA-binding transcription factor activity
CWI25_RS22090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWI25_RS22095	COG2354	Protein conserved in bacteria
CWI25_RS22100	COG3278	Belongs to the heme-copper respiratory oxidase family
CWI25_RS22110	COG2239	Acts as a magnesium transporter
CWI25_RS22125	COG5001	Diguanylate cyclase
CWI25_RS22125	COG4251	negative regulation of phosphorylation
CWI25_RS22125	COG2203	Gaf domain
CWI25_RS22125	COG3706	GGDEF domain
CWI25_RS22130	COG4977	sequence-specific DNA binding
CWI25_RS22135	COG3813	Protein conserved in bacteria
CWI25_RS22200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWI25_RS22225	COG0604	alcohol dehydrogenase
CWI25_RS22230	COG0616	signal peptide processing
CWI25_RS22250	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS22255	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS22260	COG0583	DNA-binding transcription factor activity
CWI25_RS22285	COG1024	Enoyl-CoA hydratase
CWI25_RS22295	COG0531	amino acid
CWI25_RS22310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWI25_RS22330	COG1388	LysM domain
CWI25_RS22330	COG0741	lytic transglycosylase activity
CWI25_RS22335	COG4166	transmembrane transport
CWI25_RS22340	COG4166	transmembrane transport
CWI25_RS22345	COG4174	ABC transporter (Permease)
CWI25_RS22350	COG4239	(ABC) transporter, permease
CWI25_RS22355	COG4172	Belongs to the ABC transporter superfamily
CWI25_RS22365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWI25_RS22380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWI25_RS22405	COG0745	RESPONSE REGULATOR receiver
CWI25_RS22410	COG2205	protein histidine kinase activity
CWI25_RS22415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWI25_RS22460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CWI25_RS22480	COG0589	response to stress
CWI25_RS22505	COG2201	protein-glutamate methylesterase activity
CWI25_RS22515	COG2223	nitrite transmembrane transporter activity
CWI25_RS22520	COG0515	serine threonine protein kinase
CWI25_RS22525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWI25_RS22530	COG2146	nitrite reductase [NAD(P)H] activity
CWI25_RS22535	COG0243	molybdopterin cofactor binding
CWI25_RS22555	COG0668	transmembrane transport
CWI25_RS22595	COG4067	protein conserved in archaea
CWI25_RS22595	COG0189	ligase activity
CWI25_RS22640	COG2909	trisaccharide binding
CWI25_RS22645	COG2909	trisaccharide binding
CWI25_RS22680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CWI25_RS22735	COG0519	Catalyzes the synthesis of GMP from XMP
CWI25_RS22750	COG0667	Aldo Keto reductase
CWI25_RS22765	COG0183	Belongs to the thiolase family
CWI25_RS22785	COG1305	Transglutaminase-like
CWI25_RS22795	COG2308	Evidence 4 Homologs of previously reported genes of
CWI25_RS22825	COG1317	bacterial-type flagellum organization
CWI25_RS22935	COG4789	Type iii secretion
CWI25_RS22985	COG4790	Type iii secretion
CWI25_RS22990	COG4794	Type iii secretion
CWI25_RS22995	COG4791	protein targeting
CWI25_RS23000	COG4792	protein secretion
CWI25_RS23080	COG2840	Smr protein MutS2
CWI25_RS23100	COG2815	serine threonine protein kinase
CWI25_RS23100	COG0515	serine threonine protein kinase
CWI25_RS23105	COG0631	protein serine/threonine phosphatase activity
CWI25_RS23140	COG2204	response regulator
CWI25_RS23200	COG3209	COG3209 Rhs family protein
CWI25_RS23210	COG0625	glutathione transferase activity
CWI25_RS23215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWI25_RS23230	COG3135	benzoate transporter
CWI25_RS23245	COG2130	NADP-dependent
CWI25_RS23270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWI25_RS23310	COG0745	RESPONSE REGULATOR receiver
CWI25_RS23315	COG2205	protein histidine kinase activity
CWI25_RS23340	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS23350	COG1024	Enoyl-CoA hydratase
CWI25_RS23355	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWI25_RS23360	COG2186	Transcriptional regulator
CWI25_RS23365	COG2807	transmembrane transport
CWI25_RS23370	COG0628	permease
CWI25_RS23380	COG0625	glutathione transferase activity
CWI25_RS23410	COG1022	Amp-dependent synthetase and ligase
CWI25_RS23440	COG5002	protein histidine kinase activity
CWI25_RS23440	COG0784	Response regulator, receiver
CWI25_RS23440	COG2205	protein histidine kinase activity
CWI25_RS23480	COG1846	Transcriptional regulator
CWI25_RS23485	COG2080	2 iron, 2 sulfur cluster binding
CWI25_RS23490	COG2010	Cytochrome c
CWI25_RS23490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWI25_RS23495	COG2010	Cytochrome c
CWI25_RS23495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWI25_RS23500	COG2207	Transcriptional regulator
CWI25_RS23575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWI25_RS23580	COG1053	succinate dehydrogenase
CWI25_RS23585	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CWI25_RS23590	COG2009	succinate dehydrogenase
CWI25_RS23620	COG2084	Dehydrogenase
CWI25_RS23635	COG3738	Protein conserved in bacteria
CWI25_RS23665	COG0251	oxidation-reduction process
CWI25_RS23670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS23680	COG0174	glutamine synthetase
CWI25_RS23685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS23705	COG0840	transmembrane signaling receptor activity
CWI25_RS23720	COG3278	Belongs to the heme-copper respiratory oxidase family
CWI25_RS23735	COG2010	Cytochrome c
CWI25_RS23740	COG3278	Belongs to the heme-copper respiratory oxidase family
CWI25_RS23755	COG2010	Cytochrome c
CWI25_RS23765	COG0348	domain, Protein
CWI25_RS23775	COG2217	Heavy metal translocating P-type atpase
CWI25_RS23815	COG2076	Multidrug Resistance protein
CWI25_RS23845	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS23860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWI25_RS23890	COG1196	nuclear chromosome segregation
CWI25_RS23920	COG0402	S-adenosylhomocysteine deaminase activity
CWI25_RS23935	COG2252	PERMEase
CWI25_RS23995	COG2233	PERMEase
CWI25_RS24010	COG1309	transcriptional regulator
CWI25_RS24065	COG2831	hemolysin activation secretion protein
CWI25_RS24205	COG0420	3'-5' exonuclease activity
CWI25_RS24215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWI25_RS24220	COG1074	ATP-dependent DNA helicase activity
CWI25_RS24225	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CWI25_RS24230	COG0095	Lipoate-protein ligase
CWI25_RS24235	COG0697	spore germination
CWI25_RS24250	COG0840	transmembrane signaling receptor activity
CWI25_RS24260	COG0306	phosphate transporter
CWI25_RS24320	COG4964	Belongs to the GSP D family
CWI25_RS24340	COG0433	COG0433 Predicted ATPase
CWI25_RS24380	COG0788	formyltetrahydrofolate deformylase activity
CWI25_RS24390	COG2925	Exonuclease
CWI25_RS24420	COG0714	Associated with various cellular activities
CWI25_RS24450	COG0589	response to stress
CWI25_RS24460	COG1024	Enoyl-CoA hydratase
CWI25_RS24470	COG3706	GGDEF domain
CWI25_RS24490	COG0693	protein deglycase activity
CWI25_RS24505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWI25_RS24520	COG0154	amidase activity
CWI25_RS24530	COG1473	amidohydrolase
CWI25_RS24545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWI25_RS24550	COG0426	domain, Protein
CWI25_RS24550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWI25_RS24570	COG0589	response to stress
CWI25_RS24585	COG2814	Major facilitator Superfamily
CWI25_RS24590	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS24605	COG1918	ferrous iron import across plasma membrane
CWI25_RS24620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWI25_RS24660	COG1704	LemA family
CWI25_RS24685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS24690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS24705	COG3642	lipopolysaccharide core region biosynthetic process
CWI25_RS24715	COG2205	protein histidine kinase activity
CWI25_RS24720	COG0745	RESPONSE REGULATOR receiver
CWI25_RS24755	COG3030	protein affecting phage T7 exclusion by the F plasmid
CWI25_RS24765	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS24810	COG0668	transmembrane transport
CWI25_RS24820	COG0745	RESPONSE REGULATOR receiver
CWI25_RS24835	COG2096	Adenosyltransferase
CWI25_RS24840	COG0494	nUDIX hydrolase
CWI25_RS24865	COG0739	heme binding
CWI25_RS24865	COG1196	nuclear chromosome segregation
CWI25_RS24865	COG0741	lytic transglycosylase activity
CWI25_RS24910	COG0772	Belongs to the SEDS family
CWI25_RS24925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWI25_RS24965	COG3107	peptidoglycan biosynthetic process
CWI25_RS24980	COG2823	Periplasmic or secreted lipoprotein
CWI25_RS24985	COG2969	positive regulation of protein catabolic process
CWI25_RS24990	COG0625	glutathione transferase activity
CWI25_RS24995	COG2857	Cytochrome c1
CWI25_RS25000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CWI25_RS25005	COG0723	plastoquinol--plastocyanin reductase activity
CWI25_RS25020	COG0667	Aldo Keto reductase
CWI25_RS25025	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS25040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CWI25_RS25050	COG2945	thiolester hydrolase activity
CWI25_RS25070	COG2951	lytic endotransglycosylase activity
CWI25_RS25080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWI25_RS25120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CWI25_RS25125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWI25_RS25130	COG1127	ABC transporter
CWI25_RS25140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CWI25_RS25155	COG1137	ATPase activity
CWI25_RS25210	COG0312	modulator of DNA gyrase
CWI25_RS25220	COG0312	modulator of DNA gyrase
CWI25_RS25225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWI25_RS25235	COG1530	ribonuclease E activity
CWI25_RS25250	COG1792	Involved in formation and maintenance of cell shape
CWI25_RS25255	COG1077	Cell shape determining protein MreB Mrl
CWI25_RS25275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CWI25_RS25280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWI25_RS25285	COG4676	Protein conserved in bacteria
CWI25_RS25290	COG5445	Predicted secreted protein (DUF2300)
CWI25_RS25305	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CWI25_RS25310	COG4676	Protein conserved in bacteria
CWI25_RS25315	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CWI25_RS25330	COG0747	negative chemotaxis
CWI25_RS25335	COG0747	negative chemotaxis
CWI25_RS25350	COG0747	negative chemotaxis
CWI25_RS25365	COG0747	negative chemotaxis
CWI25_RS25370	COG0601	transmembrane transport
CWI25_RS25375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWI25_RS25380	COG0444	Belongs to the ABC transporter superfamily
CWI25_RS25385	COG4608	Belongs to the ABC transporter superfamily
CWI25_RS25400	COG1984	allophanate hydrolase subunit 2
CWI25_RS25420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CWI25_RS25425	COG4774	siderophore transport
CWI25_RS25440	COG2194	sulfuric ester hydrolase activity
CWI25_RS25450	COG0019	diaminopimelate decarboxylase activity
CWI25_RS25490	COG4969	Belongs to the N-Me-Phe pilin family
CWI25_RS25555	COG1252	NADH dehydrogenase
CWI25_RS25560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CWI25_RS25565	COG2831	hemolysin activation secretion protein
CWI25_RS25675	COG1047	Peptidyl-prolyl cis-trans
CWI25_RS25690	COG0196	riboflavin kinase activity
CWI25_RS25705	COG3045	CreA protein
CWI25_RS25730	COG0142	geranyltranstransferase activity
CWI25_RS25745	COG0545	Peptidyl-prolyl cis-trans isomerase
CWI25_RS25765	COG1067	ATP-dependent peptidase activity
CWI25_RS25790	COG4650	regulator
CWI25_RS25805	COG1690	Belongs to the RtcB family
CWI25_RS25810	COG3541	Predicted nucleotidyltransferase
CWI25_RS25830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWI25_RS25855	COG1136	(ABC) transporter
CWI25_RS25855	COG0577	efflux transmembrane transporter activity
CWI25_RS25860	COG0577	efflux transmembrane transporter activity
CWI25_RS25860	COG1136	(ABC) transporter
CWI25_RS25865	COG0488	(ABC) transporter
CWI25_RS25885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWI25_RS25890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS25915	COG0523	cobalamin synthesis protein
CWI25_RS25920	COG2879	small protein
CWI25_RS25925	COG1966	Carbon starvation protein
CWI25_RS25995	COG3608	succinylglutamate desuccinylase aspartoacylase
CWI25_RS25995	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CWI25_RS26000	COG2010	Cytochrome c
CWI25_RS26040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWI25_RS26050	COG0833	amino acid
CWI25_RS26055	COG2119	membrane
CWI25_RS26070	COG0501	Belongs to the peptidase M48B family
CWI25_RS26075	COG0840	transmembrane signaling receptor activity
CWI25_RS26080	COG2135	peptidase activity
CWI25_RS26085	COG1285	pathogenesis
CWI25_RS26145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CWI25_RS26200	COG1090	epimerase
CWI25_RS26205	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CWI25_RS26215	COG0789	Transcriptional regulator
CWI25_RS26235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWI25_RS26290	COG0012	GTP binding
CWI25_RS26360	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWI25_RS26380	COG3549	Plasmid maintenance system killer
CWI25_RS26395	COG0288	reversible hydration of carbon dioxide
CWI25_RS26405	COG0456	acetyltransferase
CWI25_RS26450	COG1840	ABC-type Fe3 transport system, periplasmic component
CWI25_RS26455	COG1178	ABC-type Fe3 transport system permease component
CWI25_RS26460	COG3008	intermembrane lipid transfer
CWI25_RS26465	COG2995	paraquat-inducible protein a
CWI25_RS26470	COG2995	paraquat-inducible protein a
CWI25_RS26510	COG1183	phosphatidylcholine synthase activity
CWI25_RS26525	COG0028	Belongs to the TPP enzyme family
CWI25_RS26535	COG3098	single-species biofilm formation
CWI25_RS26545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI25_RS26580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI25_RS26585	COG4558	Periplasmic binding protein
CWI25_RS26590	COG3720	iron ion transport
CWI25_RS26595	COG4771	TonB-dependent receptor
CWI25_RS26620	COG0436	Aminotransferase
CWI25_RS26630	COG2321	neutral zinc metallopeptidase
CWI25_RS26640	COG2252	PERMEase
CWI25_RS26655	COG0436	Aminotransferase
CWI25_RS26660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWI25_RS26675	COG4191	Histidine kinase
CWI25_RS26780	COG0195	Participates in both transcription termination and antitermination
CWI25_RS26815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CWI25_RS26885	COG0497	DNA recombination
CWI25_RS26915	COG2186	Transcriptional regulator
CWI25_RS26920	COG1620	l-lactate permease
CWI25_RS26970	COG0697	spore germination
CWI25_RS26990	COG0697	spore germination
CWI25_RS26995	COG1522	sequence-specific DNA binding
CWI25_RS27005	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS27025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWI25_RS27035	COG0584	glycerophosphoryl diester phosphodiesterase
CWI25_RS27055	COG0509	glycine decarboxylation via glycine cleavage system
CWI25_RS27095	COG0531	amino acid
CWI25_RS27110	COG3276	selenocysteine insertion sequence binding
CWI25_RS27125	COG2864	formate dehydrogenase
CWI25_RS27130	COG0437	4 iron, 4 sulfur cluster binding
CWI25_RS27140	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CWI25_RS27145	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS27145	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI25_RS27170	COG0463	Glycosyl transferase, family 2
CWI25_RS27180	COG0534	Mate efflux family protein
CWI25_RS27190	COG1283	sodium-dependent phosphate transmembrane transporter activity
CWI25_RS27215	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CWI25_RS27240	COG4221	oxidoreductase activity
CWI25_RS27245	COG1272	protein, Hemolysin III
CWI25_RS27280	COG0023	Translation Initiation Factor
CWI25_RS27370	COG2095	MarC family integral membrane protein
CWI25_RS27375	COG0683	leucine binding
CWI25_RS27390	COG0411	ABC transporter
CWI25_RS27435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWI25_RS27455	COG0443	Heat shock 70 kDa protein
CWI25_RS27480	COG0789	Transcriptional regulator
CWI25_RS27485	COG2982	Protein involved in outer membrane biogenesis
CWI25_RS27490	COG2193	ferroxidase activity
CWI25_RS27500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CWI25_RS27505	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CWI25_RS27565	COG3712	iron ion homeostasis
CWI25_RS27570	COG1595	DNA-templated transcription, initiation
CWI25_RS27590	COG2814	Major facilitator Superfamily
CWI25_RS27600	COG0583	DNA-binding transcription factor activity
CWI25_RS27625	COG4221	oxidoreductase activity
CWI25_RS27630	COG2423	ornithine cyclodeaminase activity
CWI25_RS27660	COG0583	DNA-binding transcription factor activity
CWI25_RS27675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWI25_RS27715	COG0668	transmembrane transport
CWI25_RS27740	COG5001	Diguanylate cyclase
CWI25_RS27740	COG3300	MHYT domain
CWI25_RS27755	COG0305	Participates in initiation and elongation during chromosome replication
CWI25_RS27785	COG0557	exoribonuclease II activity
CWI25_RS27815	COG0330	HflC and HflK could
CWI25_RS27820	COG0330	HflC and HflK could
CWI25_RS27825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWI25_RS27845	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWI25_RS27850	COG0802	atpase or kinase
CWI25_RS27855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CWI25_RS27855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWI25_RS27910	COG3300	MHYT domain
CWI25_RS27910	COG5001	Diguanylate cyclase
CWI25_RS27915	COG3830	Belongs to the UPF0237 family
CWI25_RS27915	COG0560	Phosphoserine phosphatase
CWI25_RS27925	COG1988	membrane-bound metal-dependent
CWI25_RS27940	COG3577	Aspartyl protease
CWI25_RS27955	COG3150	esterase
CWI25_RS27960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CWI25_RS27970	COG0494	nUDIX hydrolase
CWI25_RS27985	COG1538	Outer membrane efflux protein
CWI25_RS27990	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWI25_RS28010	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS28015	COG1024	Enoyl-CoA hydratase
CWI25_RS28020	COG0833	amino acid
CWI25_RS28050	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI25_RS28050	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS28060	COG1519	Transferase
CWI25_RS28065	COG0583	DNA-binding transcription factor activity
CWI25_RS28080	COG0667	Aldo Keto reductase
CWI25_RS28090	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS28095	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS28140	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS28145	COG2192	nodulation
CWI25_RS28170	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS28175	COG0859	PFAM glycosyl transferase family 9
CWI25_RS28180	COG0859	PFAM glycosyl transferase family 9
CWI25_RS28225	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CWI25_RS28230	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS28245	COG1196	nuclear chromosome segregation
CWI25_RS28245	COG3264	Mechanosensitive ion channel
CWI25_RS28255	COG0730	response to heat
CWI25_RS28260	COG2873	o-acetylhomoserine
CWI25_RS28275	COG1192	Involved in chromosome partitioning
CWI25_RS28280	COG0583	DNA-binding transcription factor activity
CWI25_RS28285	COG2814	Major facilitator Superfamily
CWI25_RS28310	COG0493	'glutamate synthase
CWI25_RS28315	COG0067	glutamate synthase
CWI25_RS28315	COG0069	glutamate synthase activity
CWI25_RS28315	COG0070	glutamate synthase
CWI25_RS28365	COG0281	malic enzyme
CWI25_RS28385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWI25_RS28505	COG0840	transmembrane signaling receptor activity
CWI25_RS28515	COG1126	abc transporter atp-binding protein
CWI25_RS28520	COG0765	amino acid transport
CWI25_RS28550	COG1051	belongs to the nudix hydrolase family
CWI25_RS28555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI25_RS28560	COG0251	oxidation-reduction process
CWI25_RS28590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWI25_RS28610	COG2986	histidine ammonia-lyase
CWI25_RS28615	COG4175	Glycine betaine
CWI25_RS28620	COG4176	ABC-type proline glycine betaine transport system permease component
CWI25_RS28640	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CWI25_RS28675	COG0402	S-adenosylhomocysteine deaminase activity
CWI25_RS28725	COG0789	Transcriptional regulator
CWI25_RS28730	COG1217	gtp-binding protein TYPA
CWI25_RS28755	COG0668	transmembrane transport
CWI25_RS28770	COG3852	Histidine kinase
CWI25_RS28790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CWI25_RS28820	COG4942	peptidase
CWI25_RS28825	COG0793	Belongs to the peptidase S41A family
CWI25_RS28830	COG2861	carbohydrate metabolic process
CWI25_RS28890	COG0579	oxidoreductase
CWI25_RS28900	COG1194	a g-specific adenine glycosylase
CWI25_RS28910	COG0673	inositol 2-dehydrogenase activity
CWI25_RS28920	COG0582	viral genome integration into host DNA
CWI25_RS29030	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS29065	COG1846	Transcriptional regulator
CWI25_RS29075	COG1566	PFAM secretion protein HlyD family protein
CWI25_RS29080	COG2814	Major facilitator Superfamily
CWI25_RS29090	COG1088	dTDP-glucose 4,6-dehydratase activity
CWI25_RS29095	COG1091	dTDP-4-dehydrorhamnose reductase activity
CWI25_RS29170	COG0494	nUDIX hydrolase
CWI25_RS29175	COG1011	Hydrolase
CWI25_RS29180	COG1652	LysM domain
CWI25_RS29190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CWI25_RS29210	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CWI25_RS29220	COG0824	Thioesterase
CWI25_RS29225	COG1454	alcohol dehydrogenase
CWI25_RS29230	COG1960	acyl-CoA dehydrogenase activity
CWI25_RS29235	COG1024	Enoyl-CoA hydratase
CWI25_RS29235	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWI25_RS29245	COG0778	Nitroreductase
CWI25_RS29275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CWI25_RS29280	COG4067	protein conserved in archaea
CWI25_RS29280	COG0189	ligase activity
CWI25_RS29305	COG2183	response to ionizing radiation
CWI25_RS29335	COG0306	phosphate transporter
CWI25_RS29340	COG1392	Phosphate transport regulator
CWI25_RS29345	COG3025	triphosphatase activity
CWI25_RS29350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWI25_RS29380	COG1178	ABC-type Fe3 transport system permease component
CWI25_RS29390	COG0583	DNA-binding transcription factor activity
CWI25_RS29405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWI25_RS29415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWI25_RS29420	COG0006	proline dipeptidase activity
CWI25_RS29445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWI25_RS29455	COG0842	Transport permease protein
CWI25_RS29460	COG0842	Transport permease protein
CWI25_RS29460	COG1129	ABC transporter
CWI25_RS29465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI25_RS29480	COG2271	Major facilitator Superfamily
CWI25_RS29495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWI25_RS29495	COG2755	lipolytic protein G-D-S-L family
CWI25_RS29510	COG0248	Ppx GppA phosphatase
CWI25_RS29525	COG0586	Pfam SNARE associated Golgi protein
CWI25_RS29530	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CWI25_RS29535	COG2050	protein possibly involved in aromatic compounds catabolism
CWI25_RS29545	COG0672	)-iron permease
CWI25_RS29550	COG1280	lysine exporter protein (LysE YggA)
CWI25_RS29555	COG0861	Integral membrane protein TerC family
CWI25_RS29565	COG0488	(ABC) transporter
CWI25_RS29620	COG3275	phosphorelay sensor kinase activity
CWI25_RS29640	COG4104	PAAR repeat-containing protein
CWI25_RS29655	COG0598	Magnesium transport protein CorA
CWI25_RS29685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWI25_RS29755	COG0432	Pfam Uncharacterised protein family UPF0047
CWI25_RS29760	COG0004	ammonium transporteR
CWI25_RS29765	COG0347	Belongs to the P(II) protein family
CWI25_RS29775	COG0606	chelatase, subunit chli
CWI25_RS29780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWI25_RS29790	COG0583	DNA-binding transcription factor activity
CWI25_RS29805	COG0210	DNA helicase
CWI25_RS29810	COG0028	Belongs to the TPP enzyme family
CWI25_RS29820	COG0427	acetyl-CoA hydrolase
CWI25_RS29830	COG1396	sequence-specific DNA binding
CWI25_RS29830	COG1917	Cupin 2, conserved barrel domain protein
CWI25_RS29840	COG0251	oxidation-reduction process
CWI25_RS29870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI25_RS29875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWI25_RS29880	COG2814	Major facilitator Superfamily
CWI25_RS29885	COG1012	belongs to the aldehyde dehydrogenase family
CWI25_RS29890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWI25_RS29910	COG0747	negative chemotaxis
CWI25_RS29920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWI25_RS29960	COG3245	cytochrome
CWI25_RS29980	COG0708	Exodeoxyribonuclease III
CWI25_RS29995	COG1561	YicC-like family, N-terminal region
CWI25_RS30010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWI25_RS30030	COG2169	Transcriptional regulator
CWI25_RS30040	COG0583	DNA-binding transcription factor activity
CWI25_RS30045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWI25_RS30085	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CWI25_RS30090	COG0247	lactate metabolic process
CWI25_RS30095	COG0277	FAD linked oxidase domain protein
CWI25_RS30100	COG0277	FAD linked oxidase domain protein
CWI25_RS30105	COG2186	Transcriptional regulator
CWI25_RS30135	COG1253	flavin adenine dinucleotide binding
CWI25_RS30140	COG0739	heme binding
CWI25_RS30160	COG0573	inorganic phosphate transmembrane transporter activity
CWI25_RS30200	COG0477	Major facilitator Superfamily
CWI25_RS30205	COG1607	acyl-coa hydrolase
CWI25_RS30230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWI25_RS30235	COG4175	Glycine betaine
CWI25_RS30240	COG4176	ABC-type proline glycine betaine transport system permease component
CWI25_RS30250	COG1760	l-serine dehydratase
CWI25_RS30265	COG0583	DNA-binding transcription factor activity
CWI25_RS30275	COG0657	acetylesterase activity
CWI25_RS30290	COG3246	L-lysine catabolic process to acetate
CWI25_RS30345	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI25_RS30345	COG1902	pentaerythritol trinitrate reductase activity
CWI25_RS30350	COG2181	nitrate reductase activity
CWI25_RS30350	COG0247	lactate metabolic process
CWI25_RS30355	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CWI25_RS30370	COG3655	Transcriptional regulator
CWI25_RS30410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWI25_RS30410	COG1017	nitric oxide dioxygenase activity
CWI25_RS30500	COG0583	DNA-binding transcription factor activity
CWI25_RS30515	COG2391	methyltransferase activity
CWI25_RS30540	COG0511	ligase activity, forming carbon-carbon bonds
CWI25_RS30540	COG5016	pyruvate
CWI25_RS30545	COG0439	Biotin carboxylase
CWI25_RS30550	COG0583	DNA-binding transcription factor activity
CWI25_RS30565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CWI25_RS30570	COG0826	peptidase U32
CWI25_RS30590	COG0210	DNA helicase
CWI25_RS30600	COG0427	acetyl-CoA hydrolase
CWI25_RS30615	COG0438	transferase activity, transferring glycosyl groups
CWI25_RS30660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWI25_RS30665	COG2755	lipolytic protein G-D-S-L family
CWI25_RS30665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWI25_RS30705	COG0679	Auxin Efflux Carrier
CWI25_RS30715	COG2851	Citrate transporter
CWI25_RS30720	COG0861	Integral membrane protein TerC family
CWI25_RS30725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CWI25_RS30730	COG1690	Belongs to the RtcB family
CWI25_RS30775	COG0700	Nucleoside recognition
CWI25_RS30780	COG1301	dicarboxylic acid transport
CWI25_RS30805	COG5002	protein histidine kinase activity
CWI25_RS30810	COG3023	N-Acetylmuramoyl-L-alanine amidase
CWI25_RS30815	COG2095	MarC family integral membrane protein
CWI25_RS30840	COG3245	cytochrome
CWI25_RS30875	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CWI25_RS30890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWI25_RS30905	COG2011	ABC-type metal ion transport system permease component
CWI25_RS30935	COG0531	amino acid
CWI25_RS30945	COG4191	Histidine kinase
CWI25_RS30975	COG4651	solute:proton antiporter activity
CWI25_RS30975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWI25_RS30980	COG1607	acyl-coa hydrolase
CWI25_RS30990	COG1028	Short-chain dehydrogenase reductase Sdr
CWI25_RS30995	COG0174	glutamine synthetase
CWI25_RS31000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CWI25_RS31035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWI25_RS31035	COG4651	solute:proton antiporter activity
CWI25_RS31040	COG0477	Major facilitator Superfamily
CWI25_RS31050	COG2948	multi-organism process
CWI25_RS31065	COG3846	protein secretion by the type IV secretion system
CWI25_RS31080	COG3451	type IV secretory pathway VirB4
CWI25_RS31090	COG3838	Conjugal transfer protein Trbc
CWI25_RS31095	COG4962	Type ii secretion system protein e
CWI25_RS31120	COG0583	DNA-binding transcription factor activity
CWI25_RS31125	COG1846	Transcriptional regulator
CWI25_RS31130	COG2814	Major facilitator Superfamily
CWI25_RS31160	COG4959	Type IV secretory pathway protease TraF
CWI25_RS31175	COG1192	Involved in chromosome partitioning
CWI25_RS31205	COG1196	nuclear chromosome segregation
CWI25_RS31210	COG0210	DNA helicase
CWI25_RS31215	COG5489	Protein of unknown function (DUF736)
CWI25_RS31240	COG2003	Belongs to the UPF0758 family
CWI25_RS31280	COG0523	cobalamin synthesis protein
CWI25_RS31325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWI25_RS31345	COG2358	TRAP transporter, solute receptor (TAXI family
CWI25_RS31350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CWI25_RS31370	COG1349	DNA-binding transcription factor activity
CWI25_RS31430	COG1475	DNA binding
CWI25_RS31435	COG1192	Involved in chromosome partitioning