locus-tag	class	description
D7M10_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D7M10_RS00010	COG0592	DNA-directed DNA polymerase activity
D7M10_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D7M10_RS00020	COG0187	DNA topoisomerase II activity
D7M10_RS00025	COG0745	RESPONSE REGULATOR receiver
D7M10_RS00040	COG5002	protein histidine kinase activity
D7M10_RS00050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D7M10_RS00055	COG0751	glycine-tRNA ligase activity
D7M10_RS00060	COG0752	glycyl-tRNA synthetase alpha subunit
D7M10_RS00065	COG2818	Glycosylase
D7M10_RS00080	COG0569	domain protein
D7M10_RS00085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D7M10_RS00090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D7M10_RS00095	COG0242	peptide deformylase activity
D7M10_RS00100	COG0758	DNA mediated transformation
D7M10_RS00105	COG0009	L-threonylcarbamoyladenylate synthase
D7M10_RS00115	COG0408	coproporphyrinogen oxidase activity
D7M10_RS00120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D7M10_RS00135	COG3119	arylsulfatase activity
D7M10_RS00150	COG3734	2-keto-3-deoxy-galactonokinase
D7M10_RS00155	COG0800	Aldolase
D7M10_RS00160	COG4948	Mandelate Racemase Muconate Lactonizing
D7M10_RS00165	COG2271	Major facilitator Superfamily
D7M10_RS00175	COG0159	tryptophan synthase activity
D7M10_RS00195	COG3360	Dodecin
D7M10_RS00205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7M10_RS00210	COG1764	response to oxidative stress
D7M10_RS00235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D7M10_RS00240	COG0339	signal peptide processing
D7M10_RS00275	COG0659	secondary active sulfate transmembrane transporter activity
D7M10_RS00285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D7M10_RS00290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D7M10_RS00295	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D7M10_RS00325	COG0109	protoheme IX farnesyltransferase activity
D7M10_RS00340	COG2011	ABC-type metal ion transport system permease component
D7M10_RS00345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7M10_RS00360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D7M10_RS00365	COG1121	(ABC) transporter
D7M10_RS00370	COG0735	belongs to the Fur family
D7M10_RS00375	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D7M10_RS00395	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D7M10_RS00400	COG3245	cytochrome
D7M10_RS00410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7M10_RS00425	COG3023	N-Acetylmuramoyl-L-alanine amidase
D7M10_RS00430	COG5002	protein histidine kinase activity
D7M10_RS00435	COG2204	response regulator
D7M10_RS00445	COG5487	UPF0391 membrane protein
D7M10_RS00455	COG1301	dicarboxylic acid transport
D7M10_RS00460	COG0700	Nucleoside recognition
D7M10_RS00475	COG1127	ABC transporter
D7M10_RS00480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D7M10_RS00490	COG0612	Peptidase, M16
D7M10_RS00495	COG1283	sodium-dependent phosphate transmembrane transporter activity
D7M10_RS00500	COG0861	Integral membrane protein TerC family
D7M10_RS00505	COG2851	Citrate transporter
D7M10_RS00535	COG0427	acetyl-CoA hydrolase
D7M10_RS00555	COG0583	DNA-binding transcription factor activity
D7M10_RS00560	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS00565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7M10_RS00605	COG0840	transmembrane signaling receptor activity
D7M10_RS00630	COG1802	Transcriptional regulator
D7M10_RS00640	COG3300	MHYT domain
D7M10_RS00640	COG5001	Diguanylate cyclase
D7M10_RS00655	COG1538	Outer membrane efflux protein
D7M10_RS00660	COG2274	protein secretion by the type I secretion system
D7M10_RS00665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS00690	COG1595	DNA-templated transcription, initiation
D7M10_RS00700	COG4774	siderophore transport
D7M10_RS00725	COG1289	transmembrane transporter activity
D7M10_RS00735	COG1566	PFAM secretion protein HlyD family protein
D7M10_RS00750	COG5339	Protein conserved in bacteria
D7M10_RS00760	COG0457	Tetratricopeptide repeat
D7M10_RS00765	COG0726	polysaccharide deacetylase
D7M10_RS00765	COG1649	PFAM Uncharacterised BCR, COG1649
D7M10_RS00770	COG1215	transferase activity, transferring glycosyl groups
D7M10_RS00805	COG2304	oxidoreductase activity
D7M10_RS00810	COG1595	DNA-templated transcription, initiation
D7M10_RS00820	COG0583	DNA-binding transcription factor activity
D7M10_RS00835	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS00840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7M10_RS00845	COG0745	RESPONSE REGULATOR receiver
D7M10_RS00850	COG2199	diguanylate cyclase activity
D7M10_RS00870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D7M10_RS00875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D7M10_RS00880	COG4208	sulfate ABC transporter
D7M10_RS00885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D7M10_RS00905	COG2807	transmembrane transport
D7M10_RS00910	COG0590	tRNA wobble adenosine to inosine editing
D7M10_RS00920	COG0583	DNA-binding transcription factor activity
D7M10_RS00945	COG0765	amino acid transport
D7M10_RS00950	COG0765	amino acid transport
D7M10_RS00955	COG1126	abc transporter atp-binding protein
D7M10_RS00960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS00965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D7M10_RS00975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS01010	COG2011	ABC-type metal ion transport system permease component
D7M10_RS01015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7M10_RS01020	COG1464	Belongs to the NlpA lipoprotein family
D7M10_RS01045	COG1126	abc transporter atp-binding protein
D7M10_RS01050	COG0765	amino acid transport
D7M10_RS01055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS01065	COG1045	serine acetyltransferase
D7M10_RS01070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7M10_RS01075	COG2175	clavaminate synthase activity
D7M10_RS01080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7M10_RS01085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7M10_RS01090	COG4521	taurine ABC transporter
D7M10_RS01095	COG2918	glutathione biosynthetic process
D7M10_RS01105	COG2183	response to ionizing radiation
D7M10_RS01115	COG2205	protein histidine kinase activity
D7M10_RS01120	COG0189	ligase activity
D7M10_RS01125	COG0189	ligase activity
D7M10_RS01125	COG4067	protein conserved in archaea
D7M10_RS01130	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D7M10_RS01140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D7M10_RS01145	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D7M10_RS01165	COG0514	ATP-dependent DNA helicase (RecQ)
D7M10_RS01170	COG0824	Thioesterase
D7M10_RS01180	COG0243	molybdopterin cofactor binding
D7M10_RS01185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D7M10_RS01195	COG1652	LysM domain
D7M10_RS01200	COG1011	Hydrolase
D7M10_RS01205	COG0494	nUDIX hydrolase
D7M10_RS01210	COG1218	3'(2'),5'-bisphosphate nucleotidase
D7M10_RS01235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D7M10_RS01245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7M10_RS01255	COG2957	Belongs to the agmatine deiminase family
D7M10_RS01295	COG2207	Transcriptional regulator
D7M10_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS01385	COG4774	siderophore transport
D7M10_RS01400	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
D7M10_RS01405	COG1194	a g-specific adenine glycosylase
D7M10_RS01415	COG2223	nitrite transmembrane transporter activity
D7M10_RS01420	COG0131	Imidazoleglycerol-phosphate dehydratase
D7M10_RS01425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D7M10_RS01435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D7M10_RS01440	COG0107	imidazoleglycerol-phosphate synthase activity
D7M10_RS01450	COG2861	carbohydrate metabolic process
D7M10_RS01455	COG0793	Belongs to the peptidase S41A family
D7M10_RS01465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D7M10_RS01470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D7M10_RS01480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D7M10_RS01485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D7M10_RS01505	COG3852	Histidine kinase
D7M10_RS01520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D7M10_RS01520	COG0301	tRNA thio-modification
D7M10_RS01525	COG1217	gtp-binding protein TYPA
D7M10_RS01535	COG0058	SHG alpha-glucan phosphorylase activity
D7M10_RS01550	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D7M10_RS01570	COG0402	S-adenosylhomocysteine deaminase activity
D7M10_RS01575	COG2188	Transcriptional regulator
D7M10_RS01585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D7M10_RS01595	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D7M10_RS01605	COG4176	ABC-type proline glycine betaine transport system permease component
D7M10_RS01610	COG4175	Glycine betaine
D7M10_RS01615	COG2986	histidine ammonia-lyase
D7M10_RS01620	COG2986	histidine ammonia-lyase
D7M10_RS01625	COG1113	amino acid transport
D7M10_RS01630	COG1228	amidohydrolase
D7M10_RS01640	COG0596	Alpha beta hydrolase
D7M10_RS01645	COG1490	D-aminoacyl-tRNA deacylase activity
D7M10_RS01650	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
D7M10_RS01655	COG2943	transferase activity, transferring hexosyl groups
D7M10_RS01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS01670	COG0765	amino acid transport
D7M10_RS01675	COG1126	abc transporter atp-binding protein
D7M10_RS01680	COG0840	transmembrane signaling receptor activity
D7M10_RS01685	COG0840	transmembrane signaling receptor activity
D7M10_RS01700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D7M10_RS01705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D7M10_RS01710	COG0140	phosphoribosyl-ATP diphosphatase activity
D7M10_RS01715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D7M10_RS01720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D7M10_RS01730	COG2226	methyltransferase
D7M10_RS01785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D7M10_RS01790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D7M10_RS01800	COG0018	arginyl-trna synthetase
D7M10_RS01805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D7M10_RS01815	COG0254	rRNA binding
D7M10_RS01860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D7M10_RS01865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D7M10_RS01880	COG0067	glutamate synthase
D7M10_RS01880	COG0069	glutamate synthase activity
D7M10_RS01880	COG0070	glutamate synthase
D7M10_RS01885	COG0493	'glutamate synthase
D7M10_RS01895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D7M10_RS01900	COG2814	Major facilitator Superfamily
D7M10_RS01905	COG0583	DNA-binding transcription factor activity
D7M10_RS01920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7M10_RS01925	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS01935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7M10_RS01945	COG2226	methyltransferase
D7M10_RS01970	COG2986	histidine ammonia-lyase
D7M10_RS01985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D7M10_RS01995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7M10_RS02015	COG1192	Involved in chromosome partitioning
D7M10_RS02020	COG3118	belongs to the thioredoxin family
D7M10_RS02025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D7M10_RS02030	COG3264	Mechanosensitive ion channel
D7M10_RS02030	COG1196	nuclear chromosome segregation
D7M10_RS02035	COG3263	regulation of cellular component size
D7M10_RS02055	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS02065	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D7M10_RS02065	COG0506	proline dehydrogenase activity
D7M10_RS02065	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D7M10_RS02075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7M10_RS02090	COG2873	o-acetylhomoserine
D7M10_RS02095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D7M10_RS02100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D7M10_RS02120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D7M10_RS02125	COG0859	PFAM glycosyl transferase family 9
D7M10_RS02130	COG0859	PFAM glycosyl transferase family 9
D7M10_RS02135	COG0438	transferase activity, transferring glycosyl groups
D7M10_RS02145	COG3642	lipopolysaccharide core region biosynthetic process
D7M10_RS02155	COG0515	serine threonine protein kinase
D7M10_RS02160	COG4772	TonB-dependent receptor
D7M10_RS02170	COG2192	nodulation
D7M10_RS02175	COG1215	transferase activity, transferring glycosyl groups
D7M10_RS02190	COG1132	(ABC) transporter
D7M10_RS02195	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D7M10_RS02195	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D7M10_RS02200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7M10_RS02210	COG0667	Aldo Keto reductase
D7M10_RS02225	COG0583	DNA-binding transcription factor activity
D7M10_RS02230	COG1519	Transferase
D7M10_RS02235	COG1538	Outer membrane efflux protein
D7M10_RS02240	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D7M10_RS02255	COG0494	nUDIX hydrolase
D7M10_RS02265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D7M10_RS02280	COG0583	DNA-binding transcription factor activity
D7M10_RS02285	COG3150	esterase
D7M10_RS02325	COG0688	phosphatidylethanolamine metabolic process
D7M10_RS02355	COG1162	GTPase activity
D7M10_RS02360	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D7M10_RS02365	COG2860	membrane
D7M10_RS02375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D7M10_RS02375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D7M10_RS02380	COG0802	atpase or kinase
D7M10_RS02385	COG0860	N-Acetylmuramoyl-L-alanine amidase
D7M10_RS02390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D7M10_RS02395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D7M10_RS02400	COG1923	regulation of RNA biosynthetic process
D7M10_RS02405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D7M10_RS02410	COG0330	HflC and HflK could
D7M10_RS02415	COG0330	HflC and HflK could
D7M10_RS02420	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D7M10_RS02425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D7M10_RS02435	COG1178	ABC-type Fe3 transport system permease component
D7M10_RS02440	COG1840	ABC-type Fe3 transport system, periplasmic component
D7M10_RS02455	COG0557	exoribonuclease II activity
D7M10_RS02460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D7M10_RS02465	COG0360	Binds together with S18 to 16S ribosomal RNA
D7M10_RS02470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D7M10_RS02480	COG0359	binds to the 23S rRNA
D7M10_RS02485	COG0305	Participates in initiation and elongation during chromosome replication
D7M10_RS02490	COG1032	radical SAM domain protein
D7M10_RS02520	COG2307	Protein conserved in bacteria
D7M10_RS02520	COG2308	Evidence 4 Homologs of previously reported genes of
D7M10_RS02540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D7M10_RS02545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D7M10_RS02550	COG0583	DNA-binding transcription factor activity
D7M10_RS02555	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS02560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS02575	COG0559	Belongs to the binding-protein-dependent transport system permease family
D7M10_RS02595	COG4221	oxidoreductase activity
D7M10_RS02615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D7M10_RS02620	COG0830	nickel cation binding
D7M10_RS02625	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
D7M10_RS02630	COG0791	NLP P60 protein
D7M10_RS02635	COG1309	transcriptional regulator
D7M10_RS02645	COG2982	Protein involved in outer membrane biogenesis
D7M10_RS02655	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D7M10_RS02660	COG0697	spore germination
D7M10_RS02685	COG0443	Heat shock 70 kDa protein
D7M10_RS02690	COG0484	heat shock protein binding
D7M10_RS02700	COG0804	urea catabolic process
D7M10_RS02705	COG0832	Belongs to the urease beta subunit family
D7M10_RS02720	COG0831	urea catabolic process
D7M10_RS02725	COG0829	nickel cation binding
D7M10_RS02740	COG0411	ABC transporter
D7M10_RS02755	COG0683	leucine binding
D7M10_RS02765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7M10_RS02775	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D7M10_RS02830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7M10_RS02855	COG2095	MarC family integral membrane protein
D7M10_RS02865	COG0151	Belongs to the GarS family
D7M10_RS02870	COG0138	bifunctional purine biosynthesis protein purh
D7M10_RS02880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7M10_RS02890	COG2264	protein methyltransferase activity
D7M10_RS02905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D7M10_RS02930	COG0023	Translation Initiation Factor
D7M10_RS02935	COG1166	arginine decarboxylase activity
D7M10_RS02945	COG0534	Mate efflux family protein
D7M10_RS02955	COG0583	DNA-binding transcription factor activity
D7M10_RS02960	COG2373	Large extracellular alpha-helical protein
D7M10_RS02970	COG4953	penicillin-binding protein 1C
D7M10_RS02980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D7M10_RS03050	COG4964	Belongs to the GSP D family
D7M10_RS03090	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS03120	COG2814	Major facilitator Superfamily
D7M10_RS03130	COG0604	alcohol dehydrogenase
D7M10_RS03135	COG0583	DNA-binding transcription factor activity
D7M10_RS03145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D7M10_RS03150	COG0387	Pfam Sodium calcium exchanger
D7M10_RS03155	COG0583	DNA-binding transcription factor activity
D7M10_RS03185	COG1309	transcriptional regulator
D7M10_RS03190	COG2233	PERMEase
D7M10_RS03240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D7M10_RS03245	COG1074	ATP-dependent DNA helicase activity
D7M10_RS03250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7M10_RS03315	COG2274	protein secretion by the type I secretion system
D7M10_RS03320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS03330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D7M10_RS03345	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D7M10_RS03350	COG3483	tryptophan 2,3-dioxygenase activity
D7M10_RS03355	COG1113	amino acid transport
D7M10_RS03360	COG0543	2 iron, 2 sulfur cluster binding
D7M10_RS03360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7M10_RS03365	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D7M10_RS03370	COG4638	Rieske (2fe-2S)
D7M10_RS03385	COG4948	Mandelate Racemase Muconate Lactonizing
D7M10_RS03390	COG4829	muconolactone delta-isomerase
D7M10_RS03395	COG3485	protocatechuate 3,4-dioxygenase
D7M10_RS03400	COG1522	sequence-specific DNA binding
D7M10_RS03410	COG1113	amino acid transport
D7M10_RS03425	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7M10_RS03430	COG0583	DNA-binding transcription factor activity
D7M10_RS03435	COG0659	secondary active sulfate transmembrane transporter activity
D7M10_RS03445	COG2610	gluconate transmembrane transporter activity
D7M10_RS03455	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D7M10_RS03470	COG0840	transmembrane signaling receptor activity
D7M10_RS03480	COG1288	antiporter activity
D7M10_RS03510	COG3135	benzoate transporter
D7M10_RS03520	COG1595	DNA-templated transcription, initiation
D7M10_RS03525	COG3712	iron ion homeostasis
D7M10_RS03535	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D7M10_RS03540	COG0583	DNA-binding transcription factor activity
D7M10_RS03545	COG3048	D-serine ammonia-lyase activity
D7M10_RS03550	COG2610	gluconate transmembrane transporter activity
D7M10_RS03560	COG0456	acetyltransferase
D7M10_RS03560	COG0454	-acetyltransferase
D7M10_RS03570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D7M10_RS03625	COG1620	l-lactate permease
D7M10_RS03630	COG2186	Transcriptional regulator
D7M10_RS03635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D7M10_RS03645	COG2914	Belongs to the UPF0125 (RnfH) family
D7M10_RS03650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D7M10_RS03655	COG0735	belongs to the Fur family
D7M10_RS03660	COG0497	DNA recombination
D7M10_RS03665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D7M10_RS03670	COG0443	Heat shock 70 kDa protein
D7M10_RS03675	COG0484	heat shock protein binding
D7M10_RS03680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D7M10_RS03685	COG0505	Belongs to the CarA family
D7M10_RS03690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D7M10_RS03695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7M10_RS03710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D7M10_RS03720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D7M10_RS03725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7M10_RS03730	COG0149	triose-phosphate isomerase activity
D7M10_RS03735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D7M10_RS03750	COG0779	Required for maturation of 30S ribosomal subunits
D7M10_RS03755	COG0195	Participates in both transcription termination and antitermination
D7M10_RS03760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D7M10_RS03765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D7M10_RS03770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D7M10_RS03775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D7M10_RS03780	COG1185	polyribonucleotide nucleotidyltransferase activity
D7M10_RS03785	COG2823	Periplasmic or secreted lipoprotein
D7M10_RS03795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D7M10_RS03805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7M10_RS03810	COG0166	Belongs to the GPI family
D7M10_RS03815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D7M10_RS03820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D7M10_RS03835	COG2204	response regulator
D7M10_RS03840	COG4191	Histidine kinase
D7M10_RS03850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7M10_RS03860	COG0436	Aminotransferase
D7M10_RS03865	COG1489	DNA binding
D7M10_RS03875	COG4558	Periplasmic binding protein
D7M10_RS03880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7M10_RS03885	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D7M10_RS03905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D7M10_RS03915	COG3098	single-species biofilm formation
D7M10_RS03920	COG0028	Belongs to the TPP enzyme family
D7M10_RS03930	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D7M10_RS03935	COG1183	phosphatidylcholine synthase activity
D7M10_RS03940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D7M10_RS03945	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
D7M10_RS03980	COG2995	paraquat-inducible protein a
D7M10_RS03985	COG2995	paraquat-inducible protein a
D7M10_RS03990	COG3008	intermembrane lipid transfer
D7M10_RS04015	COG0456	acetyltransferase
D7M10_RS04025	COG0288	reversible hydration of carbon dioxide
D7M10_RS04040	COG2031	fatty acid transporter
D7M10_RS04075	COG0642	Histidine kinase
D7M10_RS04100	COG2207	Transcriptional regulator
D7M10_RS04110	COG0405	Gamma-glutamyltransferase
D7M10_RS04115	COG4771	TonB-dependent receptor
D7M10_RS04135	COG4977	sequence-specific DNA binding
D7M10_RS04150	COG1063	alcohol dehydrogenase
D7M10_RS04255	COG0582	viral genome integration into host DNA
D7M10_RS04265	COG2223	nitrite transmembrane transporter activity
D7M10_RS04315	COG4794	Type iii secretion
D7M10_RS04325	COG4792	protein secretion
D7M10_RS04365	COG4669	(LipO)protein
D7M10_RS04385	COG0012	GTP binding
D7M10_RS04390	COG0193	aminoacyl-tRNA hydrolase activity
D7M10_RS04395	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D7M10_RS04400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D7M10_RS04410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D7M10_RS04415	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D7M10_RS04425	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D7M10_RS04430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D7M10_RS04440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D7M10_RS04445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D7M10_RS04465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D7M10_RS04475	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D7M10_RS04480	COG4221	oxidoreductase activity
D7M10_RS04490	COG0415	Belongs to the DNA photolyase family
D7M10_RS04495	COG0789	Transcriptional regulator
D7M10_RS04510	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
D7M10_RS04515	COG1090	epimerase
D7M10_RS04535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7M10_RS04545	COG0175	sulfate reduction
D7M10_RS04555	COG0204	Acyl-transferase
D7M10_RS04560	COG0280	phosphate acetyltransferase
D7M10_RS04560	COG0857	belongs to the CobB CobQ family
D7M10_RS04570	COG1047	Peptidyl-prolyl cis-trans
D7M10_RS04575	COG0386	Belongs to the glutathione peroxidase family
D7M10_RS04595	COG1858	cytochrome C peroxidase
D7M10_RS04600	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
D7M10_RS04610	COG0492	ferredoxin-NADP+ reductase activity
D7M10_RS04625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D7M10_RS04640	COG0789	Transcriptional regulator
D7M10_RS04650	COG1366	Belongs to the anti-sigma-factor antagonist family
D7M10_RS04660	COG0583	DNA-binding transcription factor activity
D7M10_RS04665	COG1380	Effector of murein hydrolase LrgA
D7M10_RS04670	COG1346	cytolysis
D7M10_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS04700	COG2909	trisaccharide binding
D7M10_RS04710	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D7M10_RS04715	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7M10_RS04735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D7M10_RS04755	COG0814	amino acid
D7M10_RS04760	COG1760	l-serine dehydratase
D7M10_RS04765	COG0583	DNA-binding transcription factor activity
D7M10_RS04775	COG4772	TonB-dependent receptor
D7M10_RS04780	COG3712	iron ion homeostasis
D7M10_RS04785	COG1595	DNA-templated transcription, initiation
D7M10_RS04815	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D7M10_RS04820	COG4774	siderophore transport
D7M10_RS04825	COG2027	D-alanyl-D-alanine carboxypeptidase
D7M10_RS04830	COG2207	Transcriptional regulator
D7M10_RS04835	COG0697	spore germination
D7M10_RS04840	COG3604	Transcriptional regulator
D7M10_RS04845	COG1017	nitric oxide dioxygenase activity
D7M10_RS04845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7M10_RS04850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D7M10_RS04860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D7M10_RS04865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D7M10_RS04870	COG1845	cytochrome c oxidase, subunit III
D7M10_RS04880	COG0109	protoheme IX farnesyltransferase activity
D7M10_RS04945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7M10_RS04955	COG0583	DNA-binding transcription factor activity
D7M10_RS04960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS04980	COG4251	negative regulation of phosphorylation
D7M10_RS05020	COG0583	DNA-binding transcription factor activity
D7M10_RS05070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D7M10_RS05075	COG0343	queuine tRNA-ribosyltransferase activity
D7M10_RS05080	COG1862	Preprotein translocase
D7M10_RS05095	COG3134	Outer membrane lipoprotein
D7M10_RS05110	COG1045	serine acetyltransferase
D7M10_RS05120	COG1104	cysteine desulfurase activity
D7M10_RS05130	COG0316	Belongs to the HesB IscA family
D7M10_RS05135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D7M10_RS05140	COG0443	Heat shock 70 kDa protein
D7M10_RS05145	COG0633	Ferredoxin
D7M10_RS05155	COG0105	UTP biosynthetic process
D7M10_RS05160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D7M10_RS05170	COG1426	Protein conserved in bacteria
D7M10_RS05175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D7M10_RS05180	COG0124	histidyl-tRNA synthetase
D7M10_RS05195	COG1160	GTP binding
D7M10_RS05200	COG0436	Aminotransferase
D7M10_RS05205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7M10_RS05215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D7M10_RS05220	COG0739	heme binding
D7M10_RS05225	COG1570	exodeoxyribonuclease VII activity
D7M10_RS05250	COG0519	Catalyzes the synthesis of GMP from XMP
D7M10_RS05250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7M10_RS05265	COG2188	Transcriptional regulator
D7M10_RS05270	COG1263	PTS System
D7M10_RS05270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D7M10_RS05275	COG0366	Alpha amylase catalytic
D7M10_RS05285	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7M10_RS05285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7M10_RS05290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D7M10_RS05295	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D7M10_RS05300	COG0047	phosphoribosylformylglycinamidine synthase activity
D7M10_RS05300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D7M10_RS05305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D7M10_RS05315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D7M10_RS05315	COG2190	(PTS) system
D7M10_RS05315	COG1263	PTS System
D7M10_RS05320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7M10_RS05320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7M10_RS05325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D7M10_RS05330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D7M10_RS05335	COG2188	Transcriptional regulator
D7M10_RS05350	COG0494	nUDIX hydrolase
D7M10_RS05370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D7M10_RS05375	COG0477	Major facilitator Superfamily
D7M10_RS05380	COG4536	flavin adenine dinucleotide binding
D7M10_RS05390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D7M10_RS05395	COG0228	four-way junction DNA binding
D7M10_RS05400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D7M10_RS05405	COG0336	Belongs to the RNA methyltransferase TrmD family
D7M10_RS05410	COG0335	large ribosomal subunit rRNA binding
D7M10_RS05415	COG1607	acyl-coa hydrolase
D7M10_RS05420	COG4974	Belongs to the 'phage' integrase family
D7M10_RS05440	COG2205	protein histidine kinase activity
D7M10_RS05440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS05450	COG2197	response regulator
D7M10_RS05465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7M10_RS05475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D7M10_RS05480	COG1902	pentaerythritol trinitrate reductase activity
D7M10_RS05485	COG2311	Membrane
D7M10_RS05500	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
D7M10_RS05525	COG0457	Tetratricopeptide repeat
D7M10_RS05525	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D7M10_RS05540	COG2201	protein-glutamate methylesterase activity
D7M10_RS05545	COG2203	Gaf domain
D7M10_RS05545	COG3706	GGDEF domain
D7M10_RS05545	COG5001	Diguanylate cyclase
D7M10_RS05545	COG4251	negative regulation of phosphorylation
D7M10_RS05555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D7M10_RS05575	COG1073	alpha beta
D7M10_RS05605	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D7M10_RS05610	COG0563	adenylate kinase activity
D7M10_RS05615	COG1214	PFAM Peptidase M22, glycoprotease
D7M10_RS05625	COG1801	Protein of unknown function DUF72
D7M10_RS05645	COG0742	ribosomal rna small subunit methyltransferase
D7M10_RS05655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS05660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7M10_RS05680	COG2937	Belongs to the GPAT DAPAT family
D7M10_RS05695	COG2226	methyltransferase
D7M10_RS05700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D7M10_RS05705	COG1215	transferase activity, transferring glycosyl groups
D7M10_RS05710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D7M10_RS05715	COG2166	iron-sulfur cluster assembly
D7M10_RS05720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D7M10_RS05725	COG2171	N-acyltransferase activity
D7M10_RS05730	COG1393	Belongs to the ArsC family
D7M10_RS05740	COG0582	viral genome integration into host DNA
D7M10_RS05760	COG0270	DNA (cytosine-5-)-methyltransferase activity
D7M10_RS05785	COG3081	Nucleoid-associated protein
D7M10_RS05900	COG1598	PFAM Uncharacterised protein family UPF0150
D7M10_RS05905	COG1724	mRNA binding
D7M10_RS06110	COG2135	peptidase activity
D7M10_RS06130	COG0025	NhaP-type Na H and K H
D7M10_RS06140	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D7M10_RS06145	COG0024	Methionine aminopeptidase
D7M10_RS06150	COG0052	Belongs to the universal ribosomal protein uS2 family
D7M10_RS06155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D7M10_RS06160	COG0528	UMP kinase activity
D7M10_RS06165	COG0233	cytoplasmic translational termination
D7M10_RS06170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D7M10_RS06180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D7M10_RS06190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D7M10_RS06200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7M10_RS06205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D7M10_RS06210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7M10_RS06215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7M10_RS06220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D7M10_RS06225	COG0587	DNA-directed DNA polymerase activity
D7M10_RS06230	COG0825	malonyl-CoA metabolic process
D7M10_RS06235	COG0037	tRNA processing
D7M10_RS06240	COG0504	CTP synthase activity
D7M10_RS06245	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D7M10_RS06250	COG0148	phosphopyruvate hydratase activity
D7M10_RS06260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D7M10_RS06270	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D7M10_RS06275	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
D7M10_RS06280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D7M10_RS06285	COG0585	pseudouridine synthase activity
D7M10_RS06290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D7M10_RS06295	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D7M10_RS06310	COG1278	Cold shock
D7M10_RS06315	COG0717	Belongs to the dCTP deaminase family
D7M10_RS06350	COG2366	antibiotic biosynthetic process
D7M10_RS06355	COG0625	glutathione transferase activity
D7M10_RS06360	COG0653	protein targeting
D7M10_RS06420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D7M10_RS06425	COG3012	SEC-C Motif Domain Protein
D7M10_RS06455	COG1199	ATP-dependent helicase activity
D7M10_RS06490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D7M10_RS06500	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D7M10_RS06520	COG0583	DNA-binding transcription factor activity
D7M10_RS06535	COG3220	belongs to the UPF0276 family
D7M10_RS06590	COG2271	Major facilitator Superfamily
D7M10_RS06595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D7M10_RS06605	COG0306	phosphate transporter
D7M10_RS06615	COG1414	Transcriptional regulator
D7M10_RS06620	COG2814	Major facilitator Superfamily
D7M10_RS06625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7M10_RS06630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7M10_RS06635	COG0183	Belongs to the thiolase family
D7M10_RS06640	COG3485	protocatechuate 3,4-dioxygenase
D7M10_RS06645	COG3485	protocatechuate 3,4-dioxygenase
D7M10_RS06650	COG0477	Major facilitator Superfamily
D7M10_RS06660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7M10_RS06665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7M10_RS06700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS06705	COG1309	transcriptional regulator
D7M10_RS06710	COG1902	pentaerythritol trinitrate reductase activity
D7M10_RS06715	COG2814	Major facilitator Superfamily
D7M10_RS06765	COG1473	amidohydrolase
D7M10_RS06775	COG0154	amidase activity
D7M10_RS06790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7M10_RS06800	COG1704	LemA family
D7M10_RS06820	COG0697	spore germination
D7M10_RS06825	COG1629	transport
D7M10_RS06835	COG1595	DNA-templated transcription, initiation
D7M10_RS06840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7M10_RS06845	COG0235	Class ii aldolase
D7M10_RS06850	COG1396	sequence-specific DNA binding
D7M10_RS06860	COG1454	alcohol dehydrogenase
D7M10_RS06865	COG2814	Major facilitator Superfamily
D7M10_RS06900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7M10_RS06950	COG1674	ftsk spoiiie
D7M10_RS07030	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D7M10_RS07145	COG0582	viral genome integration into host DNA
D7M10_RS07155	COG2267	carboxylic ester hydrolase activity
D7M10_RS07185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D7M10_RS07235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D7M10_RS07265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7M10_RS07275	COG0425	Belongs to the sulfur carrier protein TusA family
D7M10_RS07280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D7M10_RS07290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7M10_RS07295	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D7M10_RS07300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D7M10_RS07305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D7M10_RS07400	COG2807	transmembrane transport
D7M10_RS07405	COG2910	NAD(P)H-binding
D7M10_RS07415	COG0583	DNA-binding transcription factor activity
D7M10_RS07445	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
D7M10_RS07455	COG0583	DNA-binding transcription factor activity
D7M10_RS07460	COG0174	glutamine synthetase
D7M10_RS07475	COG3100	YcgL domain-containing protein
D7M10_RS07480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7M10_RS07495	COG2983	Belongs to the UPF0260 family
D7M10_RS07540	COG1770	oligopeptidase
D7M10_RS07550	COG0121	glutamine amidotransferase
D7M10_RS07570	COG0583	DNA-binding transcription factor activity
D7M10_RS07575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D7M10_RS07580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D7M10_RS07585	COG1984	allophanate hydrolase subunit 2
D7M10_RS07595	COG0542	response to heat
D7M10_RS07605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D7M10_RS07625	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
D7M10_RS07630	COG1643	Atp-dependent helicase
D7M10_RS07640	COG1595	DNA-templated transcription, initiation
D7M10_RS07665	COG1132	(ABC) transporter
D7M10_RS07690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D7M10_RS07700	COG0668	transmembrane transport
D7M10_RS07705	COG0513	Belongs to the DEAD box helicase family
D7M10_RS07720	COG2132	Multicopper oxidase
D7M10_RS07755	COG2996	Protein conserved in bacteria
D7M10_RS07770	COG0583	DNA-binding transcription factor activity
D7M10_RS07785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7M10_RS07830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D7M10_RS07835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D7M10_RS07840	COG3956	TIGRFAM MazG family protein
D7M10_RS07845	COG3122	Protein conserved in bacteria
D7M10_RS07860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D7M10_RS07865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D7M10_RS07875	COG0628	permease
D7M10_RS07880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D7M10_RS07885	COG0791	NLP P60 protein
D7M10_RS07890	COG0791	NLP P60 protein
D7M10_RS07905	COG1797	cobyrinic acid a,c-diamide synthase activity
D7M10_RS07910	COG0778	Nitroreductase
D7M10_RS07925	COG1492	cobalamin metabolic process
D7M10_RS07935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D7M10_RS07940	COG0406	alpha-ribazole phosphatase activity
D7M10_RS07945	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D7M10_RS07950	COG1846	Transcriptional regulator
D7M10_RS08000	COG2205	protein histidine kinase activity
D7M10_RS08005	COG2832	Protein of unknown function (DUF454)
D7M10_RS08015	COG0514	ATP-dependent DNA helicase (RecQ)
D7M10_RS08025	COG1752	Esterase of the alpha-beta hydrolase superfamily
D7M10_RS08045	COG2207	Transcriptional regulator
D7M10_RS08060	COG2154	pterin-4-alpha-carbinolamine dehydratase
D7M10_RS08070	COG3283	Transcriptional regulator of aromatic amino acids metabolism
D7M10_RS08075	COG4787	bacterial-type flagellum-dependent cell motility
D7M10_RS08085	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D7M10_RS08090	COG1706	bacterial-type flagellum-dependent cell motility
D7M10_RS08115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D7M10_RS08125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D7M10_RS08155	COG1677	Flagellar hook-basal body complex protein FliE
D7M10_RS08195	COG0745	RESPONSE REGULATOR receiver
D7M10_RS08250	COG1278	Cold shock
D7M10_RS08280	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D7M10_RS08285	COG2198	Histidine kinase
D7M10_RS08285	COG0643	Histidine kinase
D7M10_RS08285	COG0784	Response regulator, receiver
D7M10_RS08290	COG2201	protein-glutamate methylesterase activity
D7M10_RS08295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D7M10_RS08305	COG1192	Involved in chromosome partitioning
D7M10_RS08315	COG0835	chemotaxis
D7M10_RS08330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D7M10_RS08340	COG4133	protoheme IX ABC transporter activity
D7M10_RS08365	COG1138	Cytochrome C-type biogenesis protein
D7M10_RS08375	COG3088	subunit of a heme lyase
D7M10_RS08380	COG4235	cytochrome complex assembly
D7M10_RS08400	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D7M10_RS08405	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
D7M10_RS08410	COG3639	organic phosphonate transmembrane transporter activity
D7M10_RS08415	COG2188	Transcriptional regulator
D7M10_RS08420	COG3624	Phosphonate C-P lyase system protein PhnG
D7M10_RS08430	COG3626	phosphonate metabolism
D7M10_RS08435	COG3627	carbon phosphorus lyase activity
D7M10_RS08440	COG4107	phosphonate C-P lyase system protein PhnK
D7M10_RS08445	COG4778	phosphonate C-P lyase system protein PhnL
D7M10_RS08450	COG3454	Phosphonate metabolism
D7M10_RS08455	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
D7M10_RS08460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D7M10_RS08470	COG1598	PFAM Uncharacterised protein family UPF0150
D7M10_RS08480	COG2814	Major facilitator Superfamily
D7M10_RS08490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7M10_RS08500	COG0469	pyruvate kinase activity
D7M10_RS08510	COG2084	Dehydrogenase
D7M10_RS08515	COG3622	Belongs to the hyi family
D7M10_RS08520	COG3960	tartronate-semialdehyde synthase activity
D7M10_RS08535	COG1309	transcriptional regulator
D7M10_RS08540	COG2354	Protein conserved in bacteria
D7M10_RS08550	COG2853	Lipoprotein
D7M10_RS08575	COG2113	Glycine betaine
D7M10_RS08580	COG3162	membrane
D7M10_RS08585	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7M10_RS08595	COG2009	succinate dehydrogenase
D7M10_RS08600	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D7M10_RS08605	COG1053	succinate dehydrogenase
D7M10_RS08610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D7M10_RS08625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7M10_RS08630	COG0045	succinate-CoA ligase (ADP-forming) activity
D7M10_RS08670	COG0326	Molecular chaperone. Has ATPase activity
D7M10_RS08680	COG1741	Belongs to the pirin family
D7M10_RS08710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D7M10_RS08715	COG2205	protein histidine kinase activity
D7M10_RS08715	COG5002	protein histidine kinase activity
D7M10_RS08715	COG0784	Response regulator, receiver
D7M10_RS08730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D7M10_RS08740	COG2062	phosphohistidine phosphatase, SixA
D7M10_RS08745	COG1022	Amp-dependent synthetase and ligase
D7M10_RS08770	COG0628	permease
D7M10_RS08775	COG0284	orotidine-5'-phosphate decarboxylase activity
D7M10_RS08780	COG2130	NADP-dependent
D7M10_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS08795	COG0840	transmembrane signaling receptor activity
D7M10_RS08800	COG2267	carboxylic ester hydrolase activity
D7M10_RS08830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D7M10_RS08835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D7M10_RS08850	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS08860	COG0625	glutathione transferase activity
D7M10_RS08865	COG1131	(ABC) transporter
D7M10_RS08870	COG0842	Transport permease protein
D7M10_RS08895	COG2076	Multidrug Resistance protein
D7M10_RS08900	COG0385	Bile acid
D7M10_RS08905	COG2974	May be involved in recombination
D7M10_RS08940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7M10_RS08960	COG2010	Cytochrome c
D7M10_RS08965	COG0545	Peptidyl-prolyl cis-trans isomerase
D7M10_RS08990	COG2200	EAL domain
D7M10_RS09000	COG0604	alcohol dehydrogenase
D7M10_RS09000	COG4221	oxidoreductase activity
D7M10_RS09000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7M10_RS09000	COG3321	synthase
D7M10_RS09005	COG0560	Phosphoserine phosphatase
D7M10_RS09010	COG3842	ATPase activity
D7M10_RS09020	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7M10_RS09040	COG0668	transmembrane transport
D7M10_RS09045	COG1362	aminopeptidase activity
D7M10_RS09050	COG0564	pseudouridine synthase activity
D7M10_RS09055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D7M10_RS09060	COG2894	cell division
D7M10_RS09065	COG0850	regulation of cytokinetic process
D7M10_RS09070	COG1560	Kdo2-lipid A biosynthetic process
D7M10_RS09085	COG2233	PERMEase
D7M10_RS09095	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
D7M10_RS09100	COG4266	Belongs to the allantoicase family
D7M10_RS09130	COG2252	PERMEase
D7M10_RS09140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS09145	COG0625	glutathione transferase activity
D7M10_RS09155	COG0302	gtp cyclohydrolase
D7M10_RS09160	COG2840	Smr protein MutS2
D7M10_RS09185	COG1073	alpha beta
D7M10_RS09190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D7M10_RS09200	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D7M10_RS09205	COG2197	response regulator
D7M10_RS09215	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS09235	COG1368	sulfuric ester hydrolase activity
D7M10_RS09250	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D7M10_RS09255	COG3089	Belongs to the UPF0270 family
D7M10_RS09265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D7M10_RS09265	COG0189	ligase activity
D7M10_RS09270	COG0367	asparagine synthase
D7M10_RS09280	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D7M10_RS09280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS09290	COG2326	polyphosphate kinase activity
D7M10_RS09295	COG0183	Belongs to the thiolase family
D7M10_RS09305	COG0697	spore germination
D7M10_RS09310	COG0114	fumarate hydratase activity
D7M10_RS09320	COG0271	Belongs to the BolA IbaG family
D7M10_RS09325	COG1054	Belongs to the UPF0176 family
D7M10_RS09340	COG5001	Diguanylate cyclase
D7M10_RS09340	COG5002	protein histidine kinase activity
D7M10_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS09365	COG0546	phosphoglycolate phosphatase activity
D7M10_RS09370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D7M10_RS09375	COG0402	S-adenosylhomocysteine deaminase activity
D7M10_RS09380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D7M10_RS09400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D7M10_RS09410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D7M10_RS09415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D7M10_RS09420	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D7M10_RS09430	COG0776	regulation of translation
D7M10_RS09445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D7M10_RS09465	COG2244	polysaccharide biosynthetic process
D7M10_RS09470	COG0463	Glycosyl transferase, family 2
D7M10_RS09500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D7M10_RS09515	COG1555	photosystem II stabilization
D7M10_RS09545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D7M10_RS09555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
D7M10_RS09560	COG2205	protein histidine kinase activity
D7M10_RS09600	COG0084	hydrolase, TatD family'
D7M10_RS09605	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D7M10_RS09630	COG1131	(ABC) transporter
D7M10_RS09640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7M10_RS09645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D7M10_RS09650	COG4181	ATPase activity
D7M10_RS09690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D7M10_RS09700	COG0589	response to stress
D7M10_RS09710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7M10_RS09725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D7M10_RS09730	COG1764	response to oxidative stress
D7M10_RS09735	COG1846	Transcriptional regulator
D7M10_RS09740	COG0583	DNA-binding transcription factor activity
D7M10_RS09745	COG0730	response to heat
D7M10_RS09750	COG0583	DNA-binding transcription factor activity
D7M10_RS09760	COG3214	Protein conserved in bacteria
D7M10_RS09765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
D7M10_RS09790	COG3384	dioxygenase
D7M10_RS09795	COG0500	methyltransferase
D7M10_RS09800	COG0501	Belongs to the peptidase M48B family
D7M10_RS09805	COG0436	Aminotransferase
D7M10_RS09810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D7M10_RS09815	COG0386	Belongs to the glutathione peroxidase family
D7M10_RS09820	COG1846	Transcriptional regulator
D7M10_RS09825	COG0784	Response regulator, receiver
D7M10_RS09825	COG2205	protein histidine kinase activity
D7M10_RS09825	COG5002	protein histidine kinase activity
D7M10_RS09835	COG1956	GAF domain-containing protein
D7M10_RS09840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS09840	COG2205	protein histidine kinase activity
D7M10_RS09845	COG2197	response regulator
D7M10_RS09860	COG2200	EAL domain
D7M10_RS09860	COG2199	diguanylate cyclase activity
D7M10_RS09860	COG3287	FIST C domain
D7M10_RS09880	COG0004	ammonium transporteR
D7M10_RS09900	COG0564	pseudouridine synthase activity
D7M10_RS09910	COG0746	molybdenum cofactor guanylyltransferase activity
D7M10_RS09915	COG0521	Mo-molybdopterin cofactor biosynthetic process
D7M10_RS09920	COG0303	'Molybdopterin
D7M10_RS09925	COG1597	lipid kinase activity
D7M10_RS09930	COG2197	response regulator
D7M10_RS09935	COG3851	Histidine kinase
D7M10_RS09955	COG3123	guanosine phosphorylase activity
D7M10_RS09970	COG1024	Enoyl-CoA hydratase
D7M10_RS09975	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS09980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7M10_RS10035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D7M10_RS10040	COG4232	protein-disulfide reductase activity
D7M10_RS10080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D7M10_RS10085	COG1121	(ABC) transporter
D7M10_RS10125	COG3829	transcription factor binding
D7M10_RS10135	COG1104	cysteine desulfurase activity
D7M10_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS10155	COG1309	transcriptional regulator
D7M10_RS10165	COG5006	permease, DMT superfamily
D7M10_RS10200	COG0768	penicillin binding
D7M10_RS10215	COG4774	siderophore transport
D7M10_RS10235	COG0473	3-isopropylmalate dehydrogenase activity
D7M10_RS10245	COG0417	DNA replication proofreading
D7M10_RS10265	COG0728	peptidoglycan biosynthetic process
D7M10_RS10330	COG3712	iron ion homeostasis
D7M10_RS10335	COG1595	DNA-templated transcription, initiation
D7M10_RS10355	COG4977	sequence-specific DNA binding
D7M10_RS10365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D7M10_RS10370	COG3387	PFAM Glycoside hydrolase 15-related
D7M10_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS10380	COG2207	Transcriptional regulator
D7M10_RS10400	COG1309	transcriptional regulator
D7M10_RS10430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7M10_RS10460	COG0657	acetylesterase activity
D7M10_RS10510	COG0577	efflux transmembrane transporter activity
D7M10_RS10510	COG1136	(ABC) transporter
D7M10_RS10515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS10530	COG2197	response regulator
D7M10_RS10535	COG2205	protein histidine kinase activity
D7M10_RS10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS10545	COG0656	L-ascorbic acid biosynthetic process
D7M10_RS10560	COG4206	TonB-dependent receptor
D7M10_RS10585	COG0475	glutathione-regulated potassium exporter activity
D7M10_RS10585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7M10_RS10630	COG5002	protein histidine kinase activity
D7M10_RS10635	COG0745	RESPONSE REGULATOR receiver
D7M10_RS10650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7M10_RS10660	COG3718	enzyme involved in inositol metabolism
D7M10_RS10665	COG3962	Belongs to the TPP enzyme family
D7M10_RS10670	COG0673	inositol 2-dehydrogenase activity
D7M10_RS10675	COG0673	inositol 2-dehydrogenase activity
D7M10_RS10685	COG1129	ABC transporter
D7M10_RS10690	COG4211	Belongs to the binding-protein-dependent transport system permease family
D7M10_RS10740	COG4774	siderophore transport
D7M10_RS10755	COG1320	monovalent cation:proton antiporter activity
D7M10_RS10760	COG2212	antiporter activity
D7M10_RS10765	COG1863	multisubunit Na H antiporter MnhE subunit
D7M10_RS10770	COG0651	ATP synthesis coupled electron transport
D7M10_RS10775	COG1006	Multisubunit Na H antiporter MnhC subunit
D7M10_RS10780	COG2111	Na H antiporter
D7M10_RS10780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D7M10_RS10805	COG0019	diaminopimelate decarboxylase activity
D7M10_RS10825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D7M10_RS10835	COG1064	alcohol dehydrogenase
D7M10_RS10990	COG1522	sequence-specific DNA binding
D7M10_RS11065	COG3011	Protein conserved in bacteria
D7M10_RS11070	COG0583	DNA-binding transcription factor activity
D7M10_RS11110	COG0154	amidase activity
D7M10_RS11115	COG2271	Major facilitator Superfamily
D7M10_RS11120	COG1609	Transcriptional regulator
D7M10_RS11130	COG2207	Transcriptional regulator
D7M10_RS11140	COG2814	Major facilitator Superfamily
D7M10_RS11155	COG1595	DNA-templated transcription, initiation
D7M10_RS11170	COG0019	diaminopimelate decarboxylase activity
D7M10_RS11180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D7M10_RS11195	COG0625	glutathione transferase activity
D7M10_RS11215	COG2989	Protein conserved in bacteria
D7M10_RS11225	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D7M10_RS11290	COG1999	signal sequence binding
D7M10_RS11325	COG2267	carboxylic ester hydrolase activity
D7M10_RS11330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7M10_RS11350	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS11365	COG0183	Belongs to the thiolase family
D7M10_RS11370	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS11385	COG0673	inositol 2-dehydrogenase activity
D7M10_RS11415	COG2706	6-phosphogluconolactonase activity
D7M10_RS11435	COG0420	3'-5' exonuclease activity
D7M10_RS11470	COG0714	Associated with various cellular activities
D7M10_RS11515	COG0519	Catalyzes the synthesis of GMP from XMP
D7M10_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS11540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7M10_RS11560	COG0814	amino acid
D7M10_RS11600	COG0589	response to stress
D7M10_RS11615	COG0745	RESPONSE REGULATOR receiver
D7M10_RS11620	COG2205	protein histidine kinase activity
D7M10_RS11630	COG3901	Regulator of nitric oxide reductase transcription
D7M10_RS11630	COG0348	domain, Protein
D7M10_RS11650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D7M10_RS11665	COG2271	Major facilitator Superfamily
D7M10_RS11880	COG3567	Phage-associated protein, HI1409 family
D7M10_RS11990	COG3728	DNA packaging
D7M10_RS11995	COG5410	chromosome segregation
D7M10_RS12010	COG3179	chitinase
D7M10_RS12060	COG3712	iron ion homeostasis
D7M10_RS12065	COG1595	DNA-templated transcription, initiation
D7M10_RS12095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7M10_RS12100	COG0601	transmembrane transport
D7M10_RS12115	COG4172	Belongs to the ABC transporter superfamily
D7M10_RS12145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS12150	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D7M10_RS12170	COG1280	lysine exporter protein (LysE YggA)
D7M10_RS12195	COG1902	pentaerythritol trinitrate reductase activity
D7M10_RS12200	COG0583	DNA-binding transcription factor activity
D7M10_RS12205	COG1090	epimerase
D7M10_RS12210	COG0789	Transcriptional regulator
D7M10_RS12230	COG0745	RESPONSE REGULATOR receiver
D7M10_RS12235	COG0642	Histidine kinase
D7M10_RS12260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D7M10_RS12265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7M10_RS12265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7M10_RS12270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D7M10_RS12270	COG2190	(PTS) system
D7M10_RS12270	COG1263	PTS System
D7M10_RS12275	COG3394	polysaccharide catabolic process
D7M10_RS12280	COG0633	Ferredoxin
D7M10_RS12280	COG3217	Mosc domain protein beta barrel domain protein
D7M10_RS12280	COG3217	Mosc domain protein beta barrel domain protein
D7M10_RS12280	COG0633	Ferredoxin
D7M10_RS12290	COG1335	isochorismatase
D7M10_RS12320	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7M10_RS12340	COG4774	siderophore transport
D7M10_RS12340	COG1629	transport
D7M10_RS12360	COG3706	GGDEF domain
D7M10_RS12365	COG4191	Histidine kinase
D7M10_RS12365	COG0784	Response regulator, receiver
D7M10_RS12375	COG0477	Major facilitator Superfamily
D7M10_RS12380	COG0579	oxidoreductase
D7M10_RS12385	COG2186	Transcriptional regulator
D7M10_RS12395	COG0583	DNA-binding transcription factor activity
D7M10_RS12410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D7M10_RS12415	COG3318	Belongs to the UPF0149 family
D7M10_RS12415	COG3012	SEC-C Motif Domain Protein
D7M10_RS12435	COG0730	response to heat
D7M10_RS12465	COG0604	alcohol dehydrogenase
D7M10_RS12475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D7M10_RS12490	COG2010	Cytochrome c
D7M10_RS12495	COG3256	nitric oxide reductase
D7M10_RS12510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7M10_RS12530	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
D7M10_RS12535	COG3604	Transcriptional regulator
D7M10_RS12545	COG0521	Mo-molybdopterin cofactor biosynthetic process
D7M10_RS12550	COG0303	'Molybdopterin
D7M10_RS12555	COG0826	peptidase U32
D7M10_RS12560	COG0826	peptidase U32
D7M10_RS12565	COG3154	lipid carrier protein
D7M10_RS12590	COG0697	spore germination
D7M10_RS12595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS12610	COG0493	'glutamate synthase
D7M10_RS12625	COG3192	ethanolamine utilization protein
D7M10_RS12640	COG1595	DNA-templated transcription, initiation
D7M10_RS12645	COG3712	iron ion homeostasis
D7M10_RS12650	COG4772	TonB-dependent receptor
D7M10_RS12715	COG1917	Cupin 2, conserved barrel domain protein
D7M10_RS12715	COG2207	Transcriptional regulator
D7M10_RS12720	COG0431	NADPH-dependent FMN reductase
D7M10_RS12725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D7M10_RS12735	COG0640	Transcriptional regulator
D7M10_RS12745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D7M10_RS12765	COG0488	(ABC) transporter
D7M10_RS12775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D7M10_RS12795	COG2169	Transcriptional regulator
D7M10_RS12795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7M10_RS12800	COG3145	DNA-N1-methyladenine dioxygenase activity
D7M10_RS12815	COG2863	cytochrome
D7M10_RS12820	COG3258	Cytochrome c
D7M10_RS12840	COG3539	Fimbrial protein
D7M10_RS12860	COG3121	Chaperone
D7M10_RS12865	COG3188	usher protein
D7M10_RS12930	COG2200	EAL domain
D7M10_RS12935	COG3121	Chaperone
D7M10_RS12950	COG1522	sequence-specific DNA binding
D7M10_RS12955	COG0667	Aldo Keto reductase
D7M10_RS12960	COG0583	DNA-binding transcription factor activity
D7M10_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS12970	COG2271	Major facilitator Superfamily
D7M10_RS12975	COG3835	regulator
D7M10_RS12980	COG1929	Belongs to the glycerate kinase type-1 family
D7M10_RS12985	COG1247	-acetyltransferase
D7M10_RS12990	COG1794	racemase activity, acting on amino acids and derivatives
D7M10_RS13010	COG3278	Belongs to the heme-copper respiratory oxidase family
D7M10_RS13015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7M10_RS13030	COG0745	RESPONSE REGULATOR receiver
D7M10_RS13035	COG2205	protein histidine kinase activity
D7M10_RS13035	COG2198	Histidine kinase
D7M10_RS13035	COG0784	Response regulator, receiver
D7M10_RS13040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D7M10_RS13050	COG2205	protein histidine kinase activity
D7M10_RS13050	COG0784	Response regulator, receiver
D7M10_RS13065	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
D7M10_RS13075	COG3781	membrane
D7M10_RS13080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7M10_RS13095	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS13100	COG1024	Enoyl-CoA hydratase
D7M10_RS13115	COG2366	antibiotic biosynthetic process
D7M10_RS13130	COG0840	transmembrane signaling receptor activity
D7M10_RS13135	COG1968	undecaprenyl-diphosphatase activity
D7M10_RS13150	COG0583	DNA-binding transcription factor activity
D7M10_RS13155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D7M10_RS13170	COG0488	(ABC) transporter
D7M10_RS13210	COG2133	pyrroloquinoline quinone binding
D7M10_RS13225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7M10_RS13235	COG2822	iron ion transport
D7M10_RS13245	COG2822	iron ion transport
D7M10_RS13250	COG0672	)-iron permease
D7M10_RS13255	COG2207	Transcriptional regulator
D7M10_RS13285	COG1280	lysine exporter protein (LysE YggA)
D7M10_RS13295	COG0789	Transcriptional regulator
D7M10_RS13355	COG0154	amidase activity
D7M10_RS13360	COG0477	Major facilitator Superfamily
D7M10_RS13370	COG2814	Major facilitator Superfamily
D7M10_RS13380	COG2267	carboxylic ester hydrolase activity
D7M10_RS13385	COG2378	regulation of single-species biofilm formation
D7M10_RS13420	COG2175	clavaminate synthase activity
D7M10_RS13430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D7M10_RS13455	COG5290	Psort location Cytoplasmic, score
D7M10_RS13470	COG2851	Citrate transporter
D7M10_RS13475	COG1301	dicarboxylic acid transport
D7M10_RS13480	COG2828	Protein conserved in bacteria
D7M10_RS13485	COG0583	DNA-binding transcription factor activity
D7M10_RS13490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D7M10_RS13510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D7M10_RS13525	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D7M10_RS13540	COG2814	Major facilitator Superfamily
D7M10_RS13550	COG3949	Membrane
D7M10_RS13555	COG0251	oxidation-reduction process
D7M10_RS13580	COG2207	Transcriptional regulator
D7M10_RS13595	COG2207	Transcriptional regulator
D7M10_RS13600	COG0300	oxidoreductase activity
D7M10_RS13610	COG2207	Transcriptional regulator
D7M10_RS13635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D7M10_RS13660	COG0667	Aldo Keto reductase
D7M10_RS13665	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS13670	COG0583	DNA-binding transcription factor activity
D7M10_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS13680	COG0604	alcohol dehydrogenase
D7M10_RS13680	COG3321	synthase
D7M10_RS13690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS13705	COG0210	DNA helicase
D7M10_RS13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS13740	COG1113	amino acid transport
D7M10_RS13785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
D7M10_RS13800	COG1199	ATP-dependent helicase activity
D7M10_RS13800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7M10_RS13805	COG2267	carboxylic ester hydrolase activity
D7M10_RS13820	COG2308	Evidence 4 Homologs of previously reported genes of
D7M10_RS13835	COG1522	sequence-specific DNA binding
D7M10_RS13845	COG0826	peptidase U32
D7M10_RS13880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D7M10_RS13910	COG2200	EAL domain
D7M10_RS13920	COG3046	protein related to deoxyribodipyrimidine photolyase
D7M10_RS13925	COG0302	gtp cyclohydrolase
D7M10_RS13945	COG3121	Chaperone
D7M10_RS13955	COG2205	protein histidine kinase activity
D7M10_RS13955	COG0784	Response regulator, receiver
D7M10_RS13970	COG2197	response regulator
D7M10_RS13980	COG3121	Chaperone
D7M10_RS13990	COG4974	Belongs to the 'phage' integrase family
D7M10_RS14000	COG0463	Glycosyl transferase, family 2
D7M10_RS14005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D7M10_RS14005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7M10_RS14010	COG0726	polysaccharide deacetylase
D7M10_RS14015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D7M10_RS14020	COG2076	Multidrug Resistance protein
D7M10_RS14025	COG2076	Multidrug Resistance protein
D7M10_RS14050	COG1024	Enoyl-CoA hydratase
D7M10_RS14055	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS14070	COG1238	metal cluster binding
D7M10_RS14075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7M10_RS14080	COG0297	glycogen (starch) synthase activity
D7M10_RS14085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D7M10_RS14090	COG1640	4-alpha-glucanotransferase
D7M10_RS14145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D7M10_RS14165	COG1285	pathogenesis
D7M10_RS14180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS14200	COG1538	Outer membrane efflux protein
D7M10_RS14250	COG1175	transmembrane transport
D7M10_RS14270	COG1070	Carbohydrate kinase
D7M10_RS14280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D7M10_RS14295	COG4574	serine-type endopeptidase inhibitor activity
D7M10_RS14300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7M10_RS14310	COG0024	Methionine aminopeptidase
D7M10_RS14315	COG0598	Magnesium transport protein CorA
D7M10_RS14320	COG0189	ligase activity
D7M10_RS14330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7M10_RS14340	COG2816	NAD+ diphosphatase activity
D7M10_RS14345	COG1024	Enoyl-CoA hydratase
D7M10_RS14350	COG2205	protein histidine kinase activity
D7M10_RS14355	COG0745	RESPONSE REGULATOR receiver
D7M10_RS14360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS14365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7M10_RS14395	COG1609	Transcriptional regulator
D7M10_RS14405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7M10_RS14425	COG2233	PERMEase
D7M10_RS14495	COG2204	response regulator
D7M10_RS14505	COG0561	phosphatase activity
D7M10_RS14510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D7M10_RS14515	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D7M10_RS14520	COG2194	sulfuric ester hydrolase activity
D7M10_RS14535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D7M10_RS14540	COG0308	aminopeptidase N
D7M10_RS14550	COG3139	Protein of unknown function (DUF1315)
D7M10_RS14555	COG0705	Rhomboid family
D7M10_RS14560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D7M10_RS14565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D7M10_RS14620	COG0316	Belongs to the HesB IscA family
D7M10_RS14620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D7M10_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS14660	COG0604	alcohol dehydrogenase
D7M10_RS14660	COG3321	synthase
D7M10_RS14670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7M10_RS14680	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS14685	COG0431	NADPH-dependent FMN reductase
D7M10_RS14710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7M10_RS14720	COG0328	RNA-DNA hybrid ribonuclease activity
D7M10_RS14730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7M10_RS14735	COG1388	LysM domain
D7M10_RS14735	COG0741	lytic transglycosylase activity
D7M10_RS14740	COG4166	transmembrane transport
D7M10_RS14745	COG4166	transmembrane transport
D7M10_RS14750	COG4174	ABC transporter (Permease)
D7M10_RS14755	COG4239	(ABC) transporter, permease
D7M10_RS14760	COG4172	Belongs to the ABC transporter superfamily
D7M10_RS14765	COG1595	DNA-templated transcription, initiation
D7M10_RS14790	COG0494	nUDIX hydrolase
D7M10_RS14800	COG1073	alpha beta
D7M10_RS14855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D7M10_RS14855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D7M10_RS14875	COG2181	nitrate reductase activity
D7M10_RS14880	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D7M10_RS14885	COG1140	nitrate reductase beta subunit
D7M10_RS14890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D7M10_RS14895	COG2223	nitrite transmembrane transporter activity
D7M10_RS14905	COG3850	Histidine kinase
D7M10_RS14910	COG2197	response regulator
D7M10_RS14915	COG0697	spore germination
D7M10_RS14920	COG0583	DNA-binding transcription factor activity
D7M10_RS14930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D7M10_RS14945	COG3712	iron ion homeostasis
D7M10_RS14950	COG1595	DNA-templated transcription, initiation
D7M10_RS14960	COG1845	cytochrome c oxidase, subunit III
D7M10_RS14965	COG0714	Associated with various cellular activities
D7M10_RS14980	COG2010	Cytochrome c
D7M10_RS14985	COG3391	amine dehydrogenase activity
D7M10_RS15010	COG0535	radical SAM domain protein
D7M10_RS15015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D7M10_RS15015	COG1648	precorrin-2 dehydrogenase activity
D7M10_RS15035	COG5001	Diguanylate cyclase
D7M10_RS15035	COG3300	MHYT domain
D7M10_RS15050	COG0515	serine threonine protein kinase
D7M10_RS15085	COG2204	response regulator
D7M10_RS15130	COG0656	L-ascorbic acid biosynthetic process
D7M10_RS15150	COG0277	FAD linked oxidase domain protein
D7M10_RS15190	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS15205	COG1136	(ABC) transporter
D7M10_RS15205	COG0577	efflux transmembrane transporter activity
D7M10_RS15210	COG0577	efflux transmembrane transporter activity
D7M10_RS15220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS15250	COG0583	DNA-binding transcription factor activity
D7M10_RS15255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7M10_RS15260	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS15265	COG1902	pentaerythritol trinitrate reductase activity
D7M10_RS15270	COG0640	Transcriptional regulator
D7M10_RS15290	COG3300	MHYT domain
D7M10_RS15290	COG5001	Diguanylate cyclase
D7M10_RS15295	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS15300	COG0154	amidase activity
D7M10_RS15305	COG1473	amidohydrolase
D7M10_RS15325	COG0583	DNA-binding transcription factor activity
D7M10_RS15360	COG2165	general secretion pathway protein
D7M10_RS15370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D7M10_RS15405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D7M10_RS15410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D7M10_RS15430	COG2226	methyltransferase
D7M10_RS15440	COG4335	DNA alkylation repair
D7M10_RS15450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7M10_RS15455	COG0154	amidase activity
D7M10_RS15460	COG0475	glutathione-regulated potassium exporter activity
D7M10_RS15470	COG1335	isochorismatase
D7M10_RS15475	COG0583	DNA-binding transcription factor activity
D7M10_RS15510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D7M10_RS15520	COG1024	Enoyl-CoA hydratase
D7M10_RS15525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7M10_RS15535	COG0583	DNA-binding transcription factor activity
D7M10_RS15550	COG3264	Mechanosensitive ion channel
D7M10_RS15550	COG1511	domain protein
D7M10_RS15555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D7M10_RS15555	COG1024	Enoyl-CoA hydratase
D7M10_RS15565	COG0789	Transcriptional regulator
D7M10_RS15590	COG3655	Transcriptional regulator
D7M10_RS15600	COG1984	allophanate hydrolase subunit 2
D7M10_RS15610	COG0439	Biotin carboxylase
D7M10_RS15620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D7M10_RS15630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7M10_RS15685	COG0322	excinuclease ABC activity
D7M10_RS15690	COG2197	response regulator
D7M10_RS15715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D7M10_RS15720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7M10_RS15725	COG4166	transmembrane transport
D7M10_RS15730	COG4174	ABC transporter (Permease)
D7M10_RS15735	COG4239	(ABC) transporter, permease
D7M10_RS15740	COG4172	Belongs to the ABC transporter superfamily
D7M10_RS15750	COG2610	gluconate transmembrane transporter activity
D7M10_RS15755	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS15760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7M10_RS15770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7M10_RS15775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7M10_RS15795	COG1126	abc transporter atp-binding protein
D7M10_RS15800	COG0765	amino acid transport
D7M10_RS15805	COG0765	amino acid transport
D7M10_RS15815	COG3118	belongs to the thioredoxin family
D7M10_RS15820	COG1253	flavin adenine dinucleotide binding
D7M10_RS15830	COG0698	ribose 5-phosphate isomerase
D7M10_RS15835	COG1129	ABC transporter
D7M10_RS15840	COG1172	Belongs to the binding-protein-dependent transport system permease family
D7M10_RS15845	COG1879	ABC-type sugar transport system periplasmic component
D7M10_RS15850	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS15855	COG1063	alcohol dehydrogenase
D7M10_RS15860	COG2376	Dihydroxyacetone kinase
D7M10_RS15870	COG0583	DNA-binding transcription factor activity
D7M10_RS15880	COG0616	signal peptide processing
D7M10_RS15895	COG5383	Protein conserved in bacteria
D7M10_RS15910	COG0784	Response regulator, receiver
D7M10_RS15910	COG4191	Histidine kinase
D7M10_RS15915	COG0587	DNA-directed DNA polymerase activity
D7M10_RS15930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D7M10_RS15935	COG0673	inositol 2-dehydrogenase activity
D7M10_RS15955	COG4774	siderophore transport
D7M10_RS15965	COG1595	DNA-templated transcription, initiation
D7M10_RS15985	COG0531	amino acid
D7M10_RS15990	COG3938	Belongs to the proline racemase family
D7M10_RS15995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7M10_RS16005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS16020	COG3121	Chaperone
D7M10_RS16030	COG0784	Response regulator, receiver
D7M10_RS16030	COG2205	protein histidine kinase activity
D7M10_RS16035	COG0784	Response regulator, receiver
D7M10_RS16035	COG2205	protein histidine kinase activity
D7M10_RS16040	COG2197	response regulator
D7M10_RS16050	COG2203	Gaf domain
D7M10_RS16050	COG4251	negative regulation of phosphorylation
D7M10_RS16050	COG3706	GGDEF domain
D7M10_RS16050	COG5001	Diguanylate cyclase
D7M10_RS16090	COG0789	Transcriptional regulator
D7M10_RS16095	COG0322	excinuclease ABC activity
D7M10_RS16145	COG2920	part of a sulfur-relay system
D7M10_RS16150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D7M10_RS16155	COG0435	Glutathione S-transferase
D7M10_RS16160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D7M10_RS16160	COG1648	precorrin-2 dehydrogenase activity
D7M10_RS16165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D7M10_RS16170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D7M10_RS16175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D7M10_RS16180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D7M10_RS16185	COG1674	ftsk spoiiie
D7M10_RS16190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D7M10_RS16195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
D7M10_RS16200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D7M10_RS16205	COG0542	response to heat
D7M10_RS16210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D7M10_RS16215	COG1278	Cold shock
D7M10_RS16230	COG0494	nUDIX hydrolase
D7M10_RS16235	COG0482	sulfurtransferase activity
D7M10_RS16240	COG2915	High frequency lysogenization protein hflD homolog
D7M10_RS16250	COG2850	peptidyl-arginine hydroxylation
D7M10_RS16255	COG2153	protein acetylation
D7M10_RS16275	COG2224	Isocitrate lyase
D7M10_RS16280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7M10_RS16285	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7M10_RS16290	COG0649	NAD binding
D7M10_RS16290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7M10_RS16305	COG1034	ATP synthesis coupled electron transport
D7M10_RS16310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D7M10_RS16315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7M10_RS16325	COG0713	ATP synthesis coupled electron transport
D7M10_RS16340	COG1007	ATP synthesis coupled electron transport
D7M10_RS16355	COG0395	ABC-type sugar transport system, permease component
D7M10_RS16365	COG3842	ATPase activity
D7M10_RS16370	COG3842	ATPase activity
D7M10_RS16375	COG3284	Transcriptional regulator
D7M10_RS16380	COG3209	COG3209 Rhs family protein
D7M10_RS16380	COG3209	COG3209 Rhs family protein
D7M10_RS16415	COG0215	cysteine-tRNA ligase activity
D7M10_RS16420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7M10_RS16430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7M10_RS16435	COG2814	Major facilitator Superfamily
D7M10_RS16440	COG1566	PFAM secretion protein HlyD family protein
D7M10_RS16445	COG1846	Transcriptional regulator
D7M10_RS16450	COG2911	Protein conserved in bacteria
D7M10_RS16455	COG0729	surface antigen
D7M10_RS16465	COG0708	Exodeoxyribonuclease III
D7M10_RS16470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D7M10_RS16475	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS16485	COG0789	Transcriptional regulator
D7M10_RS16495	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS16500	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS16505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7M10_RS16530	COG2866	Carboxypeptidase
D7M10_RS16540	COG2814	Major facilitator Superfamily
D7M10_RS16545	COG3038	cytochrome b561
D7M10_RS16565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D7M10_RS16575	COG0217	transcriptional regulatory protein
D7M10_RS16580	COG2271	Major facilitator Superfamily
D7M10_RS16590	COG0583	DNA-binding transcription factor activity
D7M10_RS16595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D7M10_RS16600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D7M10_RS16605	COG3038	cytochrome b561
D7M10_RS16615	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7M10_RS16615	COG1902	pentaerythritol trinitrate reductase activity
D7M10_RS16635	COG1846	Transcriptional regulator
D7M10_RS16640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D7M10_RS16650	COG0583	DNA-binding transcription factor activity
D7M10_RS16655	COG2814	Major facilitator Superfamily
D7M10_RS16660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7M10_RS16665	COG0776	regulation of translation
D7M10_RS16670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D7M10_RS16675	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D7M10_RS16680	COG0740	serine-type endopeptidase activity
D7M10_RS16685	COG0544	peptidyl-prolyl cis-trans isomerase activity
D7M10_RS16710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D7M10_RS16715	COG1686	Belongs to the peptidase S11 family
D7M10_RS16730	COG1953	Uracil, thiamine, allantoin
D7M10_RS16740	COG0493	'glutamate synthase
D7M10_RS16750	COG1309	transcriptional regulator
D7M10_RS16775	COG0471	metal ion transport
D7M10_RS16780	COG0154	amidase activity
D7M10_RS16795	COG2205	protein histidine kinase activity
D7M10_RS16860	COG0784	Response regulator, receiver
D7M10_RS16860	COG2205	protein histidine kinase activity
D7M10_RS16875	COG0730	response to heat
D7M10_RS16885	COG0640	Transcriptional regulator
D7M10_RS16910	COG1522	sequence-specific DNA binding
D7M10_RS16915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7M10_RS16920	COG0022	dehydrogenase e1 component
D7M10_RS16930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7M10_RS16935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D7M10_RS16945	COG0456	acetyltransferase
D7M10_RS16955	COG2423	ornithine cyclodeaminase activity
D7M10_RS16960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS16965	COG4215	(ABC) transporter
D7M10_RS17035	COG2814	Major facilitator Superfamily
D7M10_RS17055	COG0174	glutamine synthetase
D7M10_RS17060	COG4335	DNA alkylation repair
D7M10_RS17085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D7M10_RS17090	COG0517	IMP dehydrogenase activity
D7M10_RS17100	COG0583	DNA-binding transcription factor activity
D7M10_RS17105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7M10_RS17135	COG0113	porphobilinogen synthase activity
D7M10_RS17140	COG0384	phenazine biosynthesis protein PhzF
D7M10_RS17145	COG0625	glutathione transferase activity
D7M10_RS17155	COG0701	Predicted permease
D7M10_RS17160	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
D7M10_RS17165	COG0709	Synthesizes selenophosphate from selenide and ATP
D7M10_RS17170	COG1253	flavin adenine dinucleotide binding
D7M10_RS17180	COG0583	DNA-binding transcription factor activity
D7M10_RS17190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D7M10_RS17200	COG3132	Protein of unknown function, DUF480
D7M10_RS17205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D7M10_RS17225	COG0628	permease
D7M10_RS17230	COG0826	peptidase U32
D7M10_RS17240	COG2056	Na+-H+ antiporter family
D7M10_RS17245	COG0840	transmembrane signaling receptor activity
D7M10_RS17260	COG2358	TRAP transporter, solute receptor (TAXI family
D7M10_RS17290	COG3655	Transcriptional regulator
D7M10_RS17305	COG0720	synthase
D7M10_RS17310	COG1051	belongs to the nudix hydrolase family
D7M10_RS17315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D7M10_RS17325	COG0402	S-adenosylhomocysteine deaminase activity
D7M10_RS17330	COG3675	Pfam Lipase (class 3)
D7M10_RS17350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D7M10_RS17360	COG2223	nitrite transmembrane transporter activity
D7M10_RS17380	COG4772	TonB-dependent receptor
D7M10_RS17390	COG1595	DNA-templated transcription, initiation
D7M10_RS17410	COG0534	Mate efflux family protein
D7M10_RS17415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS17425	COG0174	glutamine synthetase
D7M10_RS17440	COG0022	dehydrogenase e1 component
D7M10_RS17445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7M10_RS17450	COG3284	Transcriptional regulator
D7M10_RS17465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7M10_RS17480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS17485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7M10_RS17500	COG3209	COG3209 Rhs family protein
D7M10_RS17510	COG3706	GGDEF domain
D7M10_RS17515	COG1280	lysine exporter protein (LysE YggA)
D7M10_RS17530	COG0154	amidase activity
D7M10_RS17550	COG0583	DNA-binding transcription factor activity
D7M10_RS17555	COG2186	Transcriptional regulator
D7M10_RS17610	COG1609	Transcriptional regulator
D7M10_RS17615	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS17625	COG1063	alcohol dehydrogenase
D7M10_RS17630	COG1172	Belongs to the binding-protein-dependent transport system permease family
D7M10_RS17640	COG1879	ABC-type sugar transport system periplasmic component
D7M10_RS17665	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
D7M10_RS17670	COG1522	sequence-specific DNA binding
D7M10_RS17685	COG1846	Transcriptional regulator
D7M10_RS17710	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS17715	COG3384	dioxygenase
D7M10_RS17725	COG2271	Major facilitator Superfamily
D7M10_RS17730	COG3971	2-oxopent-4-enoate hydratase activity
D7M10_RS17740	COG1846	Transcriptional regulator
D7M10_RS17745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS17765	COG0531	amino acid
D7M10_RS17780	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS17815	COG2890	protein-(glutamine-N5) methyltransferase activity
D7M10_RS17820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D7M10_RS17825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D7M10_RS17855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS17910	COG0642	Histidine kinase
D7M10_RS17965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS17965	COG2205	protein histidine kinase activity
D7M10_RS17970	COG5001	Diguanylate cyclase
D7M10_RS17975	COG2197	response regulator
D7M10_RS17990	COG3188	usher protein
D7M10_RS17995	COG3121	Chaperone
D7M10_RS18005	COG3539	Fimbrial protein
D7M10_RS18080	COG2963	transposase activity
D7M10_RS18175	COG0776	regulation of translation
D7M10_RS18180	COG0072	phenylalanine-tRNA ligase activity
D7M10_RS18185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D7M10_RS18190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D7M10_RS18195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D7M10_RS18200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D7M10_RS18205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D7M10_RS18215	COG1278	Cold shock
D7M10_RS18240	COG1869	D-ribose catabolic process
D7M10_RS18245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7M10_RS18250	COG1609	Transcriptional regulator
D7M10_RS18255	COG1172	Belongs to the binding-protein-dependent transport system permease family
D7M10_RS18260	COG1129	ABC transporter
D7M10_RS18265	COG1879	ABC-type sugar transport system periplasmic component
D7M10_RS18290	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D7M10_RS18305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D7M10_RS18335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS18370	COG1286	toxin biosynthetic process
D7M10_RS18380	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D7M10_RS18385	COG0285	dihydrofolate synthase activity
D7M10_RS18390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D7M10_RS18395	COG0135	phosphoribosylanthranilate isomerase activity
D7M10_RS18420	COG0473	3-isopropylmalate dehydrogenase activity
D7M10_RS18425	COG2226	methyltransferase
D7M10_RS18430	COG0066	3-isopropylmalate dehydratase activity
D7M10_RS18435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D7M10_RS18470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7M10_RS18480	COG0596	Alpha beta hydrolase
D7M10_RS18510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7M10_RS18515	COG0556	nucleotide-excision repair
D7M10_RS18530	COG0583	DNA-binding transcription factor activity
D7M10_RS18535	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS18545	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D7M10_RS18560	COG3038	cytochrome b561
D7M10_RS18580	COG4221	oxidoreductase activity
D7M10_RS18595	COG0642	Histidine kinase
D7M10_RS18610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D7M10_RS18625	COG2384	SAM-dependent methyltransferase
D7M10_RS18630	COG0789	Transcriptional regulator
D7M10_RS18645	COG3781	membrane
D7M10_RS18655	COG2957	Belongs to the agmatine deiminase family
D7M10_RS18670	COG2957	Belongs to the agmatine deiminase family
D7M10_RS18675	COG0583	DNA-binding transcription factor activity
D7M10_RS18690	COG2894	cell division
D7M10_RS18695	COG2197	response regulator
D7M10_RS18745	COG2267	carboxylic ester hydrolase activity
D7M10_RS18750	COG2233	PERMEase
D7M10_RS18755	COG0583	DNA-binding transcription factor activity
D7M10_RS18765	COG2814	Major facilitator Superfamily
D7M10_RS18770	COG0583	DNA-binding transcription factor activity
D7M10_RS18775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7M10_RS18790	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D7M10_RS18795	COG1611	Belongs to the LOG family
D7M10_RS18920	COG3179	chitinase
D7M10_RS19110	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
D7M10_RS19145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7M10_RS19150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D7M10_RS19170	COG2853	Lipoprotein
D7M10_RS19185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D7M10_RS19185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D7M10_RS19205	COG4591	ABC-type transport system involved in lipoprotein release permease component
D7M10_RS19210	COG1136	(ABC) transporter
D7M10_RS19215	COG4591	ABC-type transport system involved in lipoprotein release permease component
D7M10_RS19225	COG0584	glycerophosphoryl diester phosphodiesterase
D7M10_RS19230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7M10_RS19235	COG1477	protein flavinylation
D7M10_RS19250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D7M10_RS19260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D7M10_RS19310	COG0183	Belongs to the thiolase family
D7M10_RS19315	COG1024	Enoyl-CoA hydratase
D7M10_RS19315	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7M10_RS19325	COG0589	response to stress
D7M10_RS19330	COG0488	(ABC) transporter
D7M10_RS19335	COG0741	lytic transglycosylase activity
D7M10_RS19340	COG1132	(ABC) transporter
D7M10_RS19355	COG0425	Belongs to the sulfur carrier protein TusA family
D7M10_RS19360	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
D7M10_RS19375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D7M10_RS19380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D7M10_RS19395	COG0438	transferase activity, transferring glycosyl groups
D7M10_RS19405	COG0840	transmembrane signaling receptor activity
D7M10_RS19420	COG3278	Belongs to the heme-copper respiratory oxidase family
D7M10_RS19440	COG3278	Belongs to the heme-copper respiratory oxidase family
D7M10_RS19455	COG2010	Cytochrome c
D7M10_RS19470	COG0348	domain, Protein
D7M10_RS19505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7M10_RS19510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D7M10_RS19515	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS19525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D7M10_RS19530	COG2130	NADP-dependent
D7M10_RS19535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D7M10_RS19540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D7M10_RS19555	COG0840	transmembrane signaling receptor activity
D7M10_RS19580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D7M10_RS19585	COG3115	cell septum assembly
D7M10_RS19605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7M10_RS19615	COG0402	S-adenosylhomocysteine deaminase activity
D7M10_RS19620	COG1802	Transcriptional regulator
D7M10_RS19625	COG3135	benzoate transporter
D7M10_RS19630	COG3171	Protein conserved in bacteria
D7M10_RS19645	COG0116	Belongs to the methyltransferase superfamily
D7M10_RS19645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D7M10_RS19650	COG3130	regulation of translation
D7M10_RS19655	COG0167	dihydroorotate dehydrogenase activity
D7M10_RS19675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7M10_RS19675	COG1116	anion transmembrane transporter activity
D7M10_RS19680	COG3707	response regulator
D7M10_RS19685	COG2223	nitrite transmembrane transporter activity
D7M10_RS19695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7M10_RS19700	COG2146	nitrite reductase [NAD(P)H] activity
D7M10_RS19705	COG0243	molybdopterin cofactor binding
D7M10_RS19710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D7M10_RS19715	COG2885	chlorophyll binding
D7M10_RS19715	COG3047	cAMP biosynthetic process
D7M10_RS19725	COG0668	transmembrane transport
D7M10_RS19740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7M10_RS19755	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D7M10_RS19760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS19780	COG1045	serine acetyltransferase
D7M10_RS19785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D7M10_RS19805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D7M10_RS19810	COG0372	Belongs to the citrate synthase family
D7M10_RS19820	COG1802	Transcriptional regulator
D7M10_RS19825	COG0189	ligase activity
D7M10_RS19825	COG4067	protein conserved in archaea
D7M10_RS19835	COG0189	ligase activity
D7M10_RS19855	COG0560	Phosphoserine phosphatase
D7M10_RS19865	COG1953	Uracil, thiamine, allantoin
D7M10_RS19880	COG0583	DNA-binding transcription factor activity
D7M10_RS19885	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS19890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D7M10_RS19920	COG1024	Enoyl-CoA hydratase
D7M10_RS19920	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7M10_RS19930	COG0598	Magnesium transport protein CorA
D7M10_RS19935	COG0519	Catalyzes the synthesis of GMP from XMP
D7M10_RS19940	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7M10_RS19940	COG1024	Enoyl-CoA hydratase
D7M10_RS19945	COG0183	Belongs to the thiolase family
D7M10_RS19965	COG2308	Evidence 4 Homologs of previously reported genes of
D7M10_RS19995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS20000	COG2885	chlorophyll binding
D7M10_RS20000	COG3047	cAMP biosynthetic process
D7M10_RS20030	COG2207	Transcriptional regulator
D7M10_RS20035	COG1064	alcohol dehydrogenase
D7M10_RS20040	COG1414	Transcriptional regulator
D7M10_RS20090	COG0084	hydrolase, TatD family'
D7M10_RS20100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D7M10_RS20105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D7M10_RS20115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7M10_RS20120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7M10_RS20135	COG0416	fatty acid biosynthetic process
D7M10_RS20140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D7M10_RS20145	COG1399	metal-binding, possibly nucleic acid-binding protein
D7M10_RS20150	COG0424	maF-like protein
D7M10_RS20155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D7M10_RS20155	COG0616	signal peptide processing
D7M10_RS20160	COG0546	phosphoglycolate phosphatase activity
D7M10_RS20175	COG1530	ribonuclease E activity
D7M10_RS20180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D7M10_RS20185	COG3608	succinylglutamate desuccinylase aspartoacylase
D7M10_RS20185	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D7M10_RS20200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D7M10_RS20205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D7M10_RS20210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D7M10_RS20215	COG2835	tetraacyldisaccharide 4'-kinase activity
D7M10_RS20220	COG1663	tetraacyldisaccharide 4'-kinase activity
D7M10_RS20225	COG0848	biopolymer transport protein
D7M10_RS20230	COG0811	peptide transport
D7M10_RS20235	COG2333	competence protein COMEC
D7M10_RS20235	COG0658	competence protein
D7M10_RS20245	COG0784	Response regulator, receiver
D7M10_RS20245	COG2205	protein histidine kinase activity
D7M10_RS20245	COG5002	protein histidine kinase activity
D7M10_RS20250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7M10_RS20265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D7M10_RS20270	COG1393	Belongs to the ArsC family
D7M10_RS20290	COG0037	tRNA processing
D7M10_RS20300	COG3091	SprT-like family
D7M10_RS20315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7M10_RS20320	COG1301	dicarboxylic acid transport
D7M10_RS20325	COG1917	Cupin 2, conserved barrel domain protein
D7M10_RS20325	COG4977	sequence-specific DNA binding
D7M10_RS20340	COG2977	Belongs to the P-Pant transferase superfamily
D7M10_RS20345	COG2205	protein histidine kinase activity
D7M10_RS20350	COG0745	RESPONSE REGULATOR receiver
D7M10_RS20375	COG1558	bacterial-type flagellum-dependent cell motility
D7M10_RS20380	COG1815	bacterial-type flagellum-dependent cell motility
D7M10_RS20390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D7M10_RS20395	COG0835	chemotaxis
D7M10_RS20395	COG0784	Response regulator, receiver
D7M10_RS20415	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D7M10_RS20420	COG0477	Major facilitator Superfamily
D7M10_RS20425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D7M10_RS20435	COG0589	response to stress
D7M10_RS20450	COG1063	alcohol dehydrogenase
D7M10_RS20480	COG2239	Acts as a magnesium transporter
D7M10_RS20500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D7M10_RS20505	COG0527	aspartate kinase activity
D7M10_RS20510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D7M10_RS20515	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D7M10_RS20520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D7M10_RS20525	COG2988	succinylglutamate desuccinylase activity
D7M10_RS20535	COG3724	N-succinylarginine dihydrolase activity
D7M10_RS20540	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS20555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7M10_RS20580	COG4215	(ABC) transporter
D7M10_RS20585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS20590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7M10_RS20600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D7M10_RS20640	COG3706	GGDEF domain
D7M10_RS20650	COG0504	CTP synthase activity
D7M10_RS20655	COG2329	Antibiotic biosynthesis monooxygenase
D7M10_RS20665	COG0584	glycerophosphoryl diester phosphodiesterase
D7M10_RS20695	COG0306	phosphate transporter
D7M10_RS20705	COG0583	DNA-binding transcription factor activity
D7M10_RS20710	COG4941	Belongs to the sigma-70 factor family
D7M10_RS20720	COG3795	YCII-related domain
D7M10_RS20740	COG3550	peptidyl-serine autophosphorylation
D7M10_RS20755	COG0436	Aminotransferase
D7M10_RS20765	COG3265	gluconokinase activity
D7M10_RS20770	COG1609	Transcriptional regulator
D7M10_RS20780	COG0625	glutathione transferase activity
D7M10_RS20785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D7M10_RS20805	COG0242	peptide deformylase activity
D7M10_RS20810	COG1295	ribonuclease BN
D7M10_RS20815	COG3237	CsbD-like
D7M10_RS20825	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS20830	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS20835	COG2267	carboxylic ester hydrolase activity
D7M10_RS20840	COG2030	dehydratase
D7M10_RS20855	COG3530	Putative quorum-sensing-regulated virulence factor
D7M10_RS20860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D7M10_RS20870	COG0800	Aldolase
D7M10_RS20885	COG1737	Transcriptional regulator
D7M10_RS20890	COG0676	glucose-6-phosphate 1-epimerase activity
D7M10_RS20910	COG0395	ABC-type sugar transport system, permease component
D7M10_RS20915	COG1175	transmembrane transport
D7M10_RS20920	COG1653	transport
D7M10_RS20925	COG2942	2-epimerase
D7M10_RS20935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7M10_RS20940	COG0583	DNA-binding transcription factor activity
D7M10_RS20955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D7M10_RS20975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D7M10_RS21010	COG1113	amino acid transport
D7M10_RS21025	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D7M10_RS21035	COG0009	L-threonylcarbamoyladenylate synthase
D7M10_RS21045	COG2917	probably involved in intracellular septation
D7M10_RS21050	COG2350	Protein conserved in bacteria
D7M10_RS21060	COG0745	RESPONSE REGULATOR receiver
D7M10_RS21070	COG0642	Histidine kinase
D7M10_RS21075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7M10_RS21095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D7M10_RS21120	COG0509	glycine decarboxylation via glycine cleavage system
D7M10_RS21125	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D7M10_RS21125	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D7M10_RS21130	COG1760	l-serine dehydratase
D7M10_RS21135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7M10_RS21140	COG1278	Cold shock
D7M10_RS21150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D7M10_RS21155	COG0583	DNA-binding transcription factor activity
D7M10_RS21160	COG1304	FMN binding
D7M10_RS21165	COG5654	RES domain protein
D7M10_RS21185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D7M10_RS21190	COG0602	queuosine metabolic process
D7M10_RS21195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D7M10_RS21200	COG2885	chlorophyll binding
D7M10_RS21205	COG0823	Involved in the tonB-independent uptake of proteins
D7M10_RS21225	COG0824	Thioesterase
D7M10_RS21230	COG2255	four-way junction helicase activity
D7M10_RS21235	COG0632	four-way junction helicase activity
D7M10_RS21240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D7M10_RS21245	COG0217	transcriptional regulatory protein
D7M10_RS21250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D7M10_RS21265	COG0783	Belongs to the Dps family
D7M10_RS21275	COG2900	Belongs to the SlyX family
D7M10_RS21290	COG0668	transmembrane transport
D7M10_RS21295	COG1666	GTP binding
D7M10_RS21305	COG4191	Histidine kinase
D7M10_RS21305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS21310	COG2096	Adenosyltransferase
D7M10_RS21320	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D7M10_RS21325	COG0653	protein targeting
D7M10_RS21335	COG0433	COG0433 Predicted ATPase
D7M10_RS21350	COG0788	formyltetrahydrofolate deformylase activity
D7M10_RS21360	COG2925	Exonuclease
D7M10_RS21385	COG0714	Associated with various cellular activities
D7M10_RS21405	COG0469	pyruvate kinase activity
D7M10_RS21410	COG1024	Enoyl-CoA hydratase
D7M10_RS21425	COG4191	Histidine kinase
D7M10_RS21435	COG0477	Major facilitator Superfamily
D7M10_RS21455	COG2207	Transcriptional regulator
D7M10_RS21490	COG3712	iron ion homeostasis
D7M10_RS21505	COG2832	Protein of unknown function (DUF454)
D7M10_RS21510	COG0840	transmembrane signaling receptor activity
D7M10_RS21535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS21540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7M10_RS21545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS21550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7M10_RS21565	COG3642	lipopolysaccharide core region biosynthetic process
D7M10_RS21575	COG0642	Histidine kinase
D7M10_RS21585	COG0459	protein refolding
D7M10_RS21590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D7M10_RS21605	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS21615	COG3695	enzyme binding
D7M10_RS21620	COG2211	Major facilitator Superfamily
D7M10_RS21625	COG0442	prolyl-tRNA aminoacylation
D7M10_RS21635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D7M10_RS21665	COG3158	transport of potassium into the cell
D7M10_RS21670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D7M10_RS21685	COG4807	Protein conserved in bacteria
D7M10_RS21700	COG0583	DNA-binding transcription factor activity
D7M10_RS21715	COG3148	PFAM DTW domain containing protein
D7M10_RS21730	COG2137	regulation of response to DNA damage stimulus
D7M10_RS21735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D7M10_RS21740	COG1546	Belongs to the CinA family
D7M10_RS21750	COG3179	chitinase
D7M10_RS21840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D7M10_RS21850	COG0489	protein tyrosine kinase activity
D7M10_RS21855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7M10_RS21855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7M10_RS21860	COG4657	Part of a membrane complex involved in electron transport
D7M10_RS21865	COG2878	Part of a membrane complex involved in electron transport
D7M10_RS21870	COG4658	electron transport chain
D7M10_RS21885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D7M10_RS21895	COG2197	response regulator
D7M10_RS21900	COG0137	argininosuccinate synthase activity
D7M10_RS21910	COG0418	dihydroorotase activity
D7M10_RS21915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7M10_RS21920	COG0450	alkyl hydroperoxide reductase
D7M10_RS21935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D7M10_RS21940	COG0243	molybdopterin cofactor binding
D7M10_RS21945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D7M10_RS21950	COG3842	ATPase activity
D7M10_RS21955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D7M10_RS21965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D7M10_RS21980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS21985	COG0765	amino acid transport
D7M10_RS21990	COG0765	amino acid transport
D7M10_RS21995	COG1126	abc transporter atp-binding protein
D7M10_RS22015	COG2204	response regulator
D7M10_RS22020	COG4191	Histidine kinase
D7M10_RS22035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7M10_RS22050	COG2076	Multidrug Resistance protein
D7M10_RS22075	COG0583	DNA-binding transcription factor activity
D7M10_RS22080	COG1280	lysine exporter protein (LysE YggA)
D7M10_RS22085	COG0494	nUDIX hydrolase
D7M10_RS22090	COG2204	response regulator
D7M10_RS22100	COG1858	cytochrome C peroxidase
D7M10_RS22105	COG4191	Histidine kinase
D7M10_RS22115	COG0254	rRNA binding
D7M10_RS22120	COG0069	glutamate synthase activity
D7M10_RS22140	COG2246	polysaccharide biosynthetic process
D7M10_RS22155	COG1113	amino acid transport
D7M10_RS22195	COG1695	Transcriptional regulator
D7M10_RS22200	COG2375	cellular response to nickel ion
D7M10_RS22210	COG4628	conserved protein (DUF2132)
D7M10_RS22215	COG4206	TonB-dependent receptor
D7M10_RS22235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D7M10_RS22250	COG2226	methyltransferase
D7M10_RS22255	COG0500	methyltransferase
D7M10_RS22260	COG0590	tRNA wobble adenosine to inosine editing
D7M10_RS22270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D7M10_RS22275	COG1381	Involved in DNA repair and RecF pathway recombination
D7M10_RS22280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D7M10_RS22285	COG0571	ribonuclease III activity
D7M10_RS22290	COG0681	Belongs to the peptidase S26 family
D7M10_RS22295	COG0481	GTPase activity
D7M10_RS22300	COG0795	lipopolysaccharide-transporting ATPase activity
D7M10_RS22305	COG0795	lipopolysaccharide-transporting ATPase activity
D7M10_RS22310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D7M10_RS22325	COG0525	valine-tRNA ligase activity
D7M10_RS22330	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
D7M10_RS22340	COG3081	Nucleoid-associated protein
D7M10_RS22370	COG2205	protein histidine kinase activity
D7M10_RS22370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS22395	COG3121	Chaperone
D7M10_RS22400	COG3188	usher protein
D7M10_RS22405	COG3539	Fimbrial protein
D7M10_RS22410	COG3539	Fimbrial protein
D7M10_RS22415	COG2807	transmembrane transport
D7M10_RS22420	COG2186	Transcriptional regulator
D7M10_RS22430	COG1126	abc transporter atp-binding protein
D7M10_RS22435	COG0765	amino acid transport
D7M10_RS22440	COG4597	amino acid ABC transporter
D7M10_RS22445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS22450	COG0400	carboxylic ester hydrolase activity
D7M10_RS22455	COG0513	Belongs to the DEAD box helicase family
D7M10_RS22465	COG3209	COG3209 Rhs family protein
D7M10_RS22480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D7M10_RS22485	COG0315	cyclic pyranopterin monophosphate synthase activity
D7M10_RS22490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D7M10_RS22500	COG3022	response to hydroperoxide
D7M10_RS22510	COG1215	transferase activity, transferring glycosyl groups
D7M10_RS22520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS22525	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D7M10_RS22535	COG3420	alginic acid biosynthetic process
D7M10_RS22550	COG1696	Membrane protein involved in D-alanine export
D7M10_RS22565	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
D7M10_RS22565	COG0662	Cupin 2, conserved barrel domain protein
D7M10_RS22580	COG0300	oxidoreductase activity
D7M10_RS22600	COG1566	PFAM secretion protein HlyD family protein
D7M10_RS22620	COG0583	DNA-binding transcription factor activity
D7M10_RS22630	COG0784	Response regulator, receiver
D7M10_RS22630	COG0835	chemotaxis
D7M10_RS22635	COG0456	acetyltransferase
D7M10_RS22680	COG5002	protein histidine kinase activity
D7M10_RS22690	COG3706	GGDEF domain
D7M10_RS22690	COG4251	negative regulation of phosphorylation
D7M10_RS22690	COG5001	Diguanylate cyclase
D7M10_RS22690	COG2203	Gaf domain
D7M10_RS22695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D7M10_RS22700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D7M10_RS22715	COG1181	Belongs to the D-alanine--D-alanine ligase family
D7M10_RS22720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D7M10_RS22725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D7M10_RS22730	COG0772	Belongs to the SEDS family
D7M10_RS22735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D7M10_RS22740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D7M10_RS22745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D7M10_RS22750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D7M10_RS22765	COG0275	rRNA processing
D7M10_RS22770	COG2001	Belongs to the MraZ family
D7M10_RS22790	COG0792	nuclease activity
D7M10_RS22795	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D7M10_RS22800	COG2823	Periplasmic or secreted lipoprotein
D7M10_RS22805	COG2885	chlorophyll binding
D7M10_RS22830	COG1294	oxidase, subunit
D7M10_RS22845	COG3604	Transcriptional regulator
D7M10_RS22905	COG1944	ATP diphosphatase activity
D7M10_RS22925	COG0318	PFAM AMP-dependent synthetase and ligase
D7M10_RS22930	COG1280	lysine exporter protein (LysE YggA)
D7M10_RS22935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D7M10_RS22940	COG2813	Specifically methylates the guanine in position
D7M10_RS22945	COG2119	membrane
D7M10_RS22950	COG0501	Belongs to the peptidase M48B family
D7M10_RS22955	COG0840	transmembrane signaling receptor activity
D7M10_RS22960	COG2135	peptidase activity
D7M10_RS23015	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D7M10_RS23020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D7M10_RS23030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D7M10_RS23035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D7M10_RS23040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D7M10_RS23045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D7M10_RS23065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D7M10_RS23070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D7M10_RS23075	COG1127	ABC transporter
D7M10_RS23085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D7M10_RS23095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D7M10_RS23100	COG1137	ATPase activity
D7M10_RS23105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D7M10_RS23110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D7M10_RS23120	COG1660	Displays ATPase and GTPase activities
D7M10_RS23160	COG0312	modulator of DNA gyrase
D7M10_RS23165	COG3028	Belongs to the UPF0307 family
D7M10_RS23170	COG0312	modulator of DNA gyrase
D7M10_RS23175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7M10_RS23185	COG1530	ribonuclease E activity
D7M10_RS23190	COG0424	maF-like protein
D7M10_RS23200	COG1792	Involved in formation and maintenance of cell shape
D7M10_RS23205	COG1077	Cell shape determining protein MreB Mrl
D7M10_RS23210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7M10_RS23215	COG0154	amidase activity
D7M10_RS23220	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7M10_RS23225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D7M10_RS23235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7M10_RS23245	COG2721	sulfolactate sulfo-lyase activity
D7M10_RS23250	COG2271	Major facilitator Superfamily
D7M10_RS23260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7M10_RS23270	COG2186	Transcriptional regulator
D7M10_RS23275	COG2969	positive regulation of protein catabolic process
D7M10_RS23280	COG0625	glutathione transferase activity
D7M10_RS23285	COG2857	Cytochrome c1
D7M10_RS23290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D7M10_RS23295	COG0723	plastoquinol--plastocyanin reductase activity
D7M10_RS23300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D7M10_RS23305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D7M10_RS23315	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS23325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D7M10_RS23330	COG0180	Tryptophanyl-tRNA synthetase
D7M10_RS23345	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D7M10_RS23370	COG0747	negative chemotaxis
D7M10_RS23375	COG0747	negative chemotaxis
D7M10_RS23385	COG0747	negative chemotaxis
D7M10_RS23390	COG0601	transmembrane transport
D7M10_RS23395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7M10_RS23400	COG0444	Belongs to the ABC transporter superfamily
D7M10_RS23405	COG4608	Belongs to the ABC transporter superfamily
D7M10_RS23420	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D7M10_RS23445	COG0019	diaminopimelate decarboxylase activity
D7M10_RS23455	COG3128	pkhd-type hydroxylase
D7M10_RS23460	COG4774	siderophore transport
D7M10_RS23465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D7M10_RS23475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D7M10_RS23475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D7M10_RS23475	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D7M10_RS23480	COG1105	Belongs to the carbohydrate kinase PfkB family
D7M10_RS23490	COG1609	Transcriptional regulator
D7M10_RS23495	COG0084	hydrolase, TatD family'
D7M10_RS23505	COG0840	transmembrane signaling receptor activity
D7M10_RS23515	COG3023	N-Acetylmuramoyl-L-alanine amidase
D7M10_RS23560	COG0237	dephospho-CoA kinase activity
D7M10_RS23565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D7M10_RS23595	COG1252	NADH dehydrogenase
D7M10_RS23620	COG0542	response to heat
D7M10_RS23645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS23675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D7M10_RS23680	COG1047	Peptidyl-prolyl cis-trans
D7M10_RS23685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D7M10_RS23690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D7M10_RS23695	COG0196	riboflavin kinase activity
D7M10_RS23705	COG0268	Binds directly to 16S ribosomal RNA
D7M10_RS23710	COG3045	CreA protein
D7M10_RS23715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D7M10_RS23720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D7M10_RS23725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D7M10_RS23730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D7M10_RS23735	COG0142	geranyltranstransferase activity
D7M10_RS23740	COG2824	Alkylphosphonate utilization operon protein PhnA
D7M10_RS23745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D7M10_RS23750	COG0545	Peptidyl-prolyl cis-trans isomerase
D7M10_RS23755	COG2862	Uncharacterized protein family, UPF0114
D7M10_RS23770	COG1067	ATP-dependent peptidase activity
D7M10_RS23800	COG0488	(ABC) transporter
D7M10_RS23815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D7M10_RS23820	COG0523	cobalamin synthesis protein
D7M10_RS23825	COG2879	small protein
D7M10_RS23830	COG1966	Carbon starvation protein
D7M10_RS23855	COG1970	mechanosensitive ion channel activity
D7M10_RS23865	COG2197	response regulator
D7M10_RS23870	COG2813	Specifically methylates the guanine in position
D7M10_RS23880	COG1294	oxidase, subunit
D7M10_RS23885	COG1271	oxidase subunit
D7M10_RS23900	COG2252	PERMEase
D7M10_RS23905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D7M10_RS23920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D7M10_RS23925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D7M10_RS23930	COG1309	transcriptional regulator
D7M10_RS23935	COG1082	Xylose isomerase domain protein TIM barrel
D7M10_RS23935	COG3185	4-Hydroxyphenylpyruvate dioxygenase
D7M10_RS23940	COG0477	Major facilitator Superfamily
D7M10_RS23955	COG2321	neutral zinc metallopeptidase
D7M10_RS23970	COG1946	Acyl-CoA thioesterase
D7M10_RS23980	COG0123	including yeast histone deacetylase and acetoin utilization protein
D7M10_RS23985	COG2081	HI0933 family
D7M10_RS23990	COG0513	Belongs to the DEAD box helicase family
D7M10_RS23995	COG0697	spore germination
D7M10_RS24000	COG1522	sequence-specific DNA binding
D7M10_RS24005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7M10_RS24005	COG1199	ATP-dependent helicase activity
D7M10_RS24030	COG1643	Atp-dependent helicase
D7M10_RS24050	COG1522	sequence-specific DNA binding
D7M10_RS24065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D7M10_RS24070	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS24075	COG0784	Response regulator, receiver
D7M10_RS24075	COG2205	protein histidine kinase activity
D7M10_RS24075	COG2198	Histidine kinase
D7M10_RS24085	COG0352	thiamine-phosphate diphosphorylase activity
D7M10_RS24090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D7M10_RS24135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D7M10_RS24140	COG1702	phosphate starvation-inducible protein PhoH
D7M10_RS24145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D7M10_RS24150	COG4535	Mg2 and Co2 transporter CorC
D7M10_RS24155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D7M10_RS24170	COG0495	leucyl-tRNA aminoacylation
D7M10_RS24190	COG2951	lytic endotransglycosylase activity
D7M10_RS24195	COG1619	proteins homologs of microcin C7 resistance protein MccF
D7M10_RS24200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D7M10_RS24205	COG0321	lipoyl(octanoyl) transferase activity
D7M10_RS24210	COG2921	Belongs to the UPF0250 family
D7M10_RS24215	COG1686	Belongs to the peptidase S11 family
D7M10_RS24225	COG2951	lytic endotransglycosylase activity
D7M10_RS24230	COG0772	Belongs to the SEDS family
D7M10_RS24235	COG0768	penicillin binding
D7M10_RS24240	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D7M10_RS24250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D7M10_RS24255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D7M10_RS24260	COG2094	Belongs to the DNA glycosylase MPG family
D7M10_RS24270	COG0586	Pfam SNARE associated Golgi protein
D7M10_RS24285	COG1346	cytolysis
D7M10_RS24290	COG1380	Effector of murein hydrolase LrgA
D7M10_RS24305	COG0702	epimerase
D7M10_RS24320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D7M10_RS24330	COG3284	Transcriptional regulator
D7M10_RS24340	COG0531	amino acid
D7M10_RS24345	COG4303	Ethanolamine ammonia lyase large subunit
D7M10_RS24350	COG4302	ethanolamine ammonia-lyase activity
D7M10_RS24355	COG0456	acetyltransferase
D7M10_RS24360	COG0586	Pfam SNARE associated Golgi protein
D7M10_RS24365	COG3228	Belongs to the MtfA family
D7M10_RS24370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D7M10_RS24415	COG1070	Carbohydrate kinase
D7M10_RS24435	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7M10_RS24440	COG0789	Transcriptional regulator
D7M10_RS24460	COG1722	exodeoxyribonuclease VII activity
D7M10_RS24465	COG0142	geranyltranstransferase activity
D7M10_RS24470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D7M10_RS24475	COG4206	TonB-dependent receptor
D7M10_RS24480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D7M10_RS24490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D7M10_RS24500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D7M10_RS24505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D7M10_RS24510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D7M10_RS24525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7M10_RS24525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7M10_RS24530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D7M10_RS24540	COG2264	protein methyltransferase activity
D7M10_RS24550	COG3118	belongs to the thioredoxin family
D7M10_RS24580	COG3047	cAMP biosynthetic process
D7M10_RS24590	COG0668	transmembrane transport
D7M10_RS24595	COG3568	Endonuclease Exonuclease Phosphatase
D7M10_RS24600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7M10_RS24605	COG0392	lysyltransferase activity
D7M10_RS24620	COG2207	Transcriptional regulator
D7M10_RS24620	COG4753	response regulator
D7M10_RS24625	COG1335	isochorismatase
D7M10_RS24630	COG4106	trans-aconitate 2-methyltransferase activity
D7M10_RS24635	COG0629	single-stranded DNA binding
D7M10_RS24640	COG2814	Major facilitator Superfamily
D7M10_RS24645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D7M10_RS24650	COG2193	ferroxidase activity
D7M10_RS24660	COG0203	ribosomal protein L17
D7M10_RS24665	COG0202	RNA polymerase activity
D7M10_RS24670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D7M10_RS24675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D7M10_RS24680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D7M10_RS24685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D7M10_RS24695	COG0200	Binds to the 23S rRNA
D7M10_RS24700	COG1841	ribosomal large subunit assembly
D7M10_RS24705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D7M10_RS24710	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D7M10_RS24715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D7M10_RS24720	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D7M10_RS24725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D7M10_RS24730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D7M10_RS24735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D7M10_RS24740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D7M10_RS24745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D7M10_RS24750	COG0255	Belongs to the universal ribosomal protein uL29 family
D7M10_RS24755	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D7M10_RS24760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D7M10_RS24765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D7M10_RS24770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D7M10_RS24775	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D7M10_RS24780	COG0089	rRNA binding
D7M10_RS24785	COG0088	Forms part of the polypeptide exit tunnel
D7M10_RS24790	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D7M10_RS24795	COG0051	transcription antitermination factor activity, RNA binding
D7M10_RS24800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D7M10_RS24805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D7M10_RS24810	COG0049	tRNA binding
D7M10_RS24815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D7M10_RS24820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D7M10_RS24825	COG0085	RNA polymerase activity
D7M10_RS24830	COG0222	ribosome binding
D7M10_RS24835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D7M10_RS24840	COG0081	regulation of translation
D7M10_RS24845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D7M10_RS24925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D7M10_RS24935	COG0739	heme binding
D7M10_RS24940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D7M10_RS24945	COG0316	Belongs to the HesB IscA family
D7M10_RS24950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D7M10_RS24955	COG1981	membrane
D7M10_RS24970	COG4221	oxidoreductase activity
D7M10_RS24975	COG0537	adenosine 5'-monophosphoramidase activity
D7M10_RS24980	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
D7M10_RS24985	COG1765	OsmC-like protein
D7M10_RS25000	COG0134	indole-3-glycerol-phosphate synthase activity
D7M10_RS25005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D7M10_RS25010	COG0512	Glutamine amidotransferase of anthranilate synthase
D7M10_RS25015	COG4625	pathogenesis
D7M10_RS25015	COG3240	lipase activity
D7M10_RS25025	COG0546	phosphoglycolate phosphatase activity
D7M10_RS25035	COG1454	alcohol dehydrogenase
D7M10_RS25045	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7M10_RS25055	COG3842	ATPase activity
D7M10_RS25060	COG2197	response regulator
D7M10_RS25080	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D7M10_RS25085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D7M10_RS25090	COG3178	'Phosphotransferase
D7M10_RS25095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D7M10_RS25100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7M10_RS25105	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D7M10_RS25110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D7M10_RS25115	COG2967	ApaG domain
D7M10_RS25120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D7M10_RS25125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D7M10_RS25130	COG2766	serine protein kinase
D7M10_RS25135	COG2718	Belongs to the UPF0229 family
D7M10_RS25140	COG2719	SpoVR family
D7M10_RS25145	COG0617	tRNA 3'-terminal CCA addition
D7M10_RS25155	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D7M10_RS25160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D7M10_RS25165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D7M10_RS25170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D7M10_RS25175	COG0358	DNA primase activity
D7M10_RS25180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D7M10_RS25205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7M10_RS25210	COG1025	Belongs to the peptidase M16 family
D7M10_RS25220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D7M10_RS25225	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
D7M10_RS25235	COG0535	radical SAM domain protein
D7M10_RS25255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7M10_RS25260	COG0583	DNA-binding transcription factor activity
D7M10_RS25265	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS25270	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS25275	COG3706	GGDEF domain
D7M10_RS25280	COG1960	acyl-CoA dehydrogenase activity
D7M10_RS25300	COG2226	methyltransferase
D7M10_RS25300	COG1073	alpha beta
D7M10_RS25305	COG0156	8-amino-7-oxononanoate synthase activity
D7M10_RS25310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D7M10_RS25320	COG2005	Transcriptional regulator
D7M10_RS25320	COG3585	molybdate ion transport
D7M10_RS25325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D7M10_RS25340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D7M10_RS25355	COG0745	RESPONSE REGULATOR receiver
D7M10_RS25355	COG4566	intracellular signal transduction
D7M10_RS25370	COG1595	DNA-templated transcription, initiation
D7M10_RS25380	COG4774	siderophore transport
D7M10_RS25405	COG4452	Inner membrane protein CreD
D7M10_RS25410	COG2205	protein histidine kinase activity
D7M10_RS25415	COG0745	RESPONSE REGULATOR receiver
D7M10_RS25420	COG0189	ligase activity
D7M10_RS25420	COG4067	protein conserved in archaea
D7M10_RS25425	COG0204	Acyl-transferase
D7M10_RS25445	COG1063	alcohol dehydrogenase
D7M10_RS25480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D7M10_RS25505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7M10_RS25505	COG1017	nitric oxide dioxygenase activity
D7M10_RS25515	COG4638	Rieske (2fe-2S)
D7M10_RS25530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D7M10_RS25535	COG2181	nitrate reductase activity
D7M10_RS25535	COG0247	lactate metabolic process
D7M10_RS25540	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7M10_RS25540	COG1902	pentaerythritol trinitrate reductase activity
D7M10_RS25580	COG3246	L-lysine catabolic process to acetate
D7M10_RS25585	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7M10_RS25605	COG1760	l-serine dehydratase
D7M10_RS25620	COG4175	Glycine betaine
D7M10_RS25625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7M10_RS25630	COG1309	transcriptional regulator
D7M10_RS25635	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS25640	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D7M10_RS25645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7M10_RS25665	COG0477	Major facilitator Superfamily
D7M10_RS25670	COG0513	Belongs to the DEAD box helicase family
D7M10_RS25675	COG2081	HI0933 family
D7M10_RS25680	COG1289	transmembrane transporter activity
D7M10_RS25690	COG2153	protein acetylation
D7M10_RS25700	COG1451	nucleotide metabolic process
D7M10_RS25735	COG0126	phosphoglycerate kinase activity
D7M10_RS25740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D7M10_RS25745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D7M10_RS25750	COG0640	Transcriptional regulator
D7M10_RS25755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D7M10_RS25765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D7M10_RS25770	COG1422	Protein of unknown function (DUF1090)
D7M10_RS25800	COG2116	formate transmembrane transporter activity
D7M10_RS25815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D7M10_RS25820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D7M10_RS25830	COG0513	Belongs to the DEAD box helicase family
D7M10_RS25835	COG2353	YceI-like domain
D7M10_RS25840	COG3038	cytochrome b561
D7M10_RS25850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D7M10_RS25855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS25875	COG1272	protein, Hemolysin III
D7M10_RS25895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D7M10_RS25915	COG3052	prosthetic group binding
D7M10_RS25920	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
D7M10_RS25955	COG0784	Response regulator, receiver
D7M10_RS25955	COG0643	Histidine kinase
D7M10_RS25955	COG2198	Histidine kinase
D7M10_RS25980	COG0189	ligase activity
D7M10_RS25990	COG1678	Uncharacterized ACR, COG1678
D7M10_RS25995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D7M10_RS26000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D7M10_RS26005	COG0540	Belongs to the ATCase OTCase family
D7M10_RS26010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D7M10_RS26020	COG0791	NLP P60 protein
D7M10_RS26050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7M10_RS26055	COG2813	Specifically methylates the guanine in position
D7M10_RS26055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7M10_RS26065	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D7M10_RS26070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D7M10_RS26080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D7M10_RS26085	COG2022	thiamine diphosphate biosynthetic process
D7M10_RS26095	COG2363	Small membrane protein
D7M10_RS26100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D7M10_RS26110	COG2177	Part of the ABC transporter FtsEX involved in
D7M10_RS26115	COG2884	Cell division ATP-binding protein ftsE
D7M10_RS26120	COG0552	protein localization to endoplasmic reticulum
D7M10_RS26125	COG0612	Peptidase, M16
D7M10_RS26130	COG0612	Peptidase, M16
D7M10_RS26135	COG0742	ribosomal rna small subunit methyltransferase
D7M10_RS26140	COG0429	hydrolase of the alpha beta-hydrolase fold
D7M10_RS26150	COG1309	transcriptional regulator
D7M10_RS26165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D7M10_RS26170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D7M10_RS26175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7M10_RS26180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D7M10_RS26190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D7M10_RS26195	COG2814	Major facilitator Superfamily
D7M10_RS26200	COG0129	dihydroxy-acid dehydratase activity
D7M10_RS26210	COG1396	sequence-specific DNA binding
D7M10_RS26220	COG1823	symporter activity
D7M10_RS26235	COG1160	GTP binding
D7M10_RS26250	COG1840	ABC-type Fe3 transport system, periplasmic component
D7M10_RS26255	COG1178	ABC-type Fe3 transport system permease component
D7M10_RS26260	COG3842	ATPase activity
D7M10_RS26265	COG0583	DNA-binding transcription factor activity
D7M10_RS26275	COG0789	Transcriptional regulator
D7M10_RS26280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D7M10_RS26285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D7M10_RS26295	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
D7M10_RS26300	COG0494	nUDIX hydrolase
D7M10_RS26315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7M10_RS26320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D7M10_RS26325	COG2234	aminopeptidase activity
D7M10_RS26330	COG3204	pilus organization
D7M10_RS26335	COG3204	pilus organization
D7M10_RS26340	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7M10_RS26345	COG0277	FAD linked oxidase domain protein
D7M10_RS26355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7M10_RS26365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS26370	COG1683	Conserved Protein
D7M10_RS26415	COG1177	transmembrane transport
D7M10_RS26420	COG1176	ABC-type spermidine putrescine transport system, permease component I
D7M10_RS26425	COG3842	ATPase activity
D7M10_RS26445	COG0174	glutamine synthetase
D7M10_RS26450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D7M10_RS26455	COG0174	glutamine synthetase
D7M10_RS26475	COG1116	anion transmembrane transporter activity
D7M10_RS26480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7M10_RS26485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7M10_RS26490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7M10_RS26495	COG0431	NADPH-dependent FMN reductase
D7M10_RS26500	COG0450	alkyl hydroperoxide reductase
D7M10_RS26510	COG4521	taurine ABC transporter
D7M10_RS26515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D7M10_RS26515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D7M10_RS26530	COG1522	sequence-specific DNA binding
D7M10_RS26540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D7M10_RS26545	COG0330	HflC and HflK could
D7M10_RS26560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D7M10_RS26565	COG0509	glycine decarboxylation via glycine cleavage system
D7M10_RS26570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D7M10_RS26575	COG1178	ABC-type Fe3 transport system permease component
D7M10_RS26585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7M10_RS26595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7M10_RS26600	COG0006	proline dipeptidase activity
D7M10_RS26605	COG3079	Belongs to the UPF0149 family
D7M10_RS26625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D7M10_RS26635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7M10_RS26640	COG1129	ABC transporter
D7M10_RS26640	COG0842	Transport permease protein
D7M10_RS26645	COG0842	Transport permease protein
D7M10_RS26660	COG2271	Major facilitator Superfamily
D7M10_RS26680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D7M10_RS26695	COG2186	Transcriptional regulator
D7M10_RS26700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7M10_RS26705	COG0765	amino acid transport
D7M10_RS26710	COG0765	amino acid transport
D7M10_RS26715	COG1126	abc transporter atp-binding protein
D7M10_RS26725	COG3188	usher protein
D7M10_RS26730	COG3121	Chaperone
D7M10_RS26740	COG0248	Ppx GppA phosphatase
D7M10_RS26745	COG0154	amidase activity
D7M10_RS26750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D7M10_RS26760	COG0586	Pfam SNARE associated Golgi protein
D7M10_RS26770	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D7M10_RS26775	COG0672	)-iron permease
D7M10_RS26800	COG1280	lysine exporter protein (LysE YggA)
D7M10_RS26810	COG0488	(ABC) transporter
D7M10_RS26835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D7M10_RS26855	COG0181	hydroxymethylbilane synthase activity
D7M10_RS26870	COG0165	Argininosuccinate lyase
D7M10_RS26880	COG0625	glutathione transferase activity
D7M10_RS26905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7M10_RS26915	COG1965	Belongs to the frataxin family
D7M10_RS26925	COG0019	diaminopimelate decarboxylase activity
D7M10_RS26930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D7M10_RS26940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D7M10_RS26945	COG1011	Hydrolase
D7M10_RS26960	COG0004	ammonium transporteR
D7M10_RS26965	COG0347	Belongs to the P(II) protein family
D7M10_RS26975	COG0606	chelatase, subunit chli
D7M10_RS26990	COG0840	transmembrane signaling receptor activity
D7M10_RS26995	COG0583	DNA-binding transcription factor activity
D7M10_RS27000	COG0534	Mate efflux family protein
D7M10_RS27015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D7M10_RS27020	COG0427	acetyl-CoA hydrolase
D7M10_RS27035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D7M10_RS27040	COG0251	oxidation-reduction process
D7M10_RS27045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS27060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7M10_RS27070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7M10_RS27075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7M10_RS27085	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS27095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D7M10_RS27100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D7M10_RS27105	COG0747	negative chemotaxis
D7M10_RS27110	COG2003	Belongs to the UPF0758 family
D7M10_RS27115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D7M10_RS27120	COG0756	dUTP diphosphatase activity
D7M10_RS27125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7M10_RS27130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D7M10_RS27135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D7M10_RS27140	COG0708	Exodeoxyribonuclease III
D7M10_RS27150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D7M10_RS27155	COG1561	YicC-like family, N-terminal region
D7M10_RS27160	COG0194	GDP metabolic process
D7M10_RS27165	COG1758	RNA polymerase activity
D7M10_RS27170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D7M10_RS27195	COG0848	biopolymer transport protein
D7M10_RS27205	COG0583	DNA-binding transcription factor activity
D7M10_RS27210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D7M10_RS27240	COG1136	(ABC) transporter
D7M10_RS27245	COG0515	serine threonine protein kinase
D7M10_RS27245	COG2815	serine threonine protein kinase
D7M10_RS27385	COG3161	chorismate lyase activity
D7M10_RS27390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D7M10_RS27410	COG1253	flavin adenine dinucleotide binding
D7M10_RS27415	COG0739	heme binding
D7M10_RS27425	COG0704	Plays a role in the regulation of phosphate uptake
D7M10_RS27430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D7M10_RS27435	COG0573	inorganic phosphate transmembrane transporter activity
D7M10_RS27460	COG0477	Major facilitator Superfamily
D7M10_RS27465	COG1607	acyl-coa hydrolase
D7M10_RS27495	COG0583	DNA-binding transcription factor activity
D7M10_RS27500	COG1027	Aspartate ammonia-lyase
D7M10_RS27515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7M10_RS27520	COG1028	Short-chain dehydrogenase reductase Sdr
D7M10_RS27535	COG1414	Transcriptional regulator
D7M10_RS27555	COG1012	belongs to the aldehyde dehydrogenase family
D7M10_RS27565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7M10_RS27585	COG0251	oxidation-reduction process
D7M10_RS27610	COG1115	amino acid carrier protein
D7M10_RS27615	COG0252	asparaginase activity
D7M10_RS27665	COG5016	pyruvate
D7M10_RS27665	COG0511	ligase activity, forming carbon-carbon bonds
D7M10_RS27670	COG0439	Biotin carboxylase
D7M10_RS27675	COG0583	DNA-binding transcription factor activity
D7M10_RS27695	COG0210	DNA helicase
D7M10_RS27735	COG4651	solute:proton antiporter activity
D7M10_RS27735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7M10_RS27740	COG1607	acyl-coa hydrolase
D7M10_RS27745	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D7M10_RS27755	COG0523	cobalamin synthesis protein
D7M10_RS27780	COG1469	GTP cyclohydrolase I activity
D7M10_RS27785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D7M10_RS27795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D7M10_RS27805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7M10_RS27810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D7M10_RS27820	COG3220	belongs to the UPF0276 family
D7M10_RS27830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D7M10_RS27835	COG2267	carboxylic ester hydrolase activity
D7M10_RS27840	COG0671	phosphoesterase, PA-phosphatase related
D7M10_RS27840	COG2453	phosphatase
D7M10_RS27855	COG4589	Belongs to the CDS family
D7M10_RS27880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D7M10_RS27890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D7M10_RS27895	COG1349	DNA-binding transcription factor activity
D7M10_RS27900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D7M10_RS27910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D7M10_RS27915	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D7M10_RS27920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D7M10_RS27925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D7M10_RS27930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D7M10_RS27935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D7M10_RS27945	COG0356	it plays a direct role in the translocation of protons across the membrane
D7M10_RS27950	COG3312	ion transport
D7M10_RS27955	COG1475	DNA binding
D7M10_RS27960	COG1192	Involved in chromosome partitioning
D7M10_RS27965	COG0357	Ribosomal RNA small subunit methyltransferase G
D7M10_RS27970	COG0445	tRNA wobble uridine modification
D7M10_RS27980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D7M10_RS27985	COG0706	membrane insertase activity
D7M10_RS27990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D7M10_RS27995	COG0594	ribonuclease P activity
D7M10_RS28000	COG0230	Belongs to the bacterial ribosomal protein bL34 family