locus-tag	class	description
PSEFU_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PSEFU_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PSEFU_RS00030	COG4589	Belongs to the CDS family
PSEFU_RS00045	COG2453	phosphatase
PSEFU_RS00045	COG0671	phosphoesterase, PA-phosphatase related
PSEFU_RS00050	COG2267	carboxylic ester hydrolase activity
PSEFU_RS00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PSEFU_RS00070	COG0751	glycine-tRNA ligase activity
PSEFU_RS00095	COG2818	Glycosylase
PSEFU_RS00115	COG1126	abc transporter atp-binding protein
PSEFU_RS00120	COG0765	amino acid transport
PSEFU_RS00125	COG0765	amino acid transport
PSEFU_RS00130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSEFU_RS00135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSEFU_RS00140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PSEFU_RS00145	COG2423	ornithine cyclodeaminase activity
PSEFU_RS00150	COG0006	proline dipeptidase activity
PSEFU_RS00155	COG3608	succinylglutamate desuccinylase aspartoacylase
PSEFU_RS00160	COG1522	sequence-specific DNA binding
PSEFU_RS00170	COG0791	NLP P60 protein
PSEFU_RS00175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PSEFU_RS00180	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS00185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PSEFU_RS00190	COG2814	Major facilitator Superfamily
PSEFU_RS00195	COG0583	DNA-binding transcription factor activity
PSEFU_RS00210	COG0569	domain protein
PSEFU_RS00215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PSEFU_RS00220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSEFU_RS00225	COG0242	peptide deformylase activity
PSEFU_RS00230	COG1652	LysM domain
PSEFU_RS00235	COG0758	DNA mediated transformation
PSEFU_RS00240	COG0009	L-threonylcarbamoyladenylate synthase
PSEFU_RS00250	COG0408	coproporphyrinogen oxidase activity
PSEFU_RS00255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSEFU_RS00285	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSEFU_RS00315	COG2358	TRAP transporter, solute receptor (TAXI family
PSEFU_RS00345	COG1349	DNA-binding transcription factor activity
PSEFU_RS00365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PSEFU_RS00370	COG3395	kinase activity
PSEFU_RS00375	COG1454	alcohol dehydrogenase
PSEFU_RS00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSEFU_RS00385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSEFU_RS00390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PSEFU_RS00395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSEFU_RS00405	COG3842	ATPase activity
PSEFU_RS00410	COG1177	transmembrane transport
PSEFU_RS00415	COG1176	ABC-type spermidine putrescine transport system, permease component I
PSEFU_RS00425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSEFU_RS00445	COG1397	ADP-ribosylglycohydrolase
PSEFU_RS00450	COG2188	Transcriptional regulator
PSEFU_RS00455	COG0583	DNA-binding transcription factor activity
PSEFU_RS00470	COG2186	Transcriptional regulator
PSEFU_RS00475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSEFU_RS00480	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS00485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSEFU_RS00490	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS00495	COG2267	carboxylic ester hydrolase activity
PSEFU_RS00505	COG1469	GTP cyclohydrolase I activity
PSEFU_RS00535	COG0523	cobalamin synthesis protein
PSEFU_RS00545	COG0477	Major facilitator Superfamily
PSEFU_RS00565	COG4651	solute:proton antiporter activity
PSEFU_RS00565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSEFU_RS00570	COG1607	acyl-coa hydrolase
PSEFU_RS00580	COG4651	solute:proton antiporter activity
PSEFU_RS00580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSEFU_RS00595	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PSEFU_RS00645	COG2814	Major facilitator Superfamily
PSEFU_RS00650	COG0659	secondary active sulfate transmembrane transporter activity
PSEFU_RS00660	COG3119	arylsulfatase activity
PSEFU_RS00665	COG0583	DNA-binding transcription factor activity
PSEFU_RS00680	COG1686	Belongs to the peptidase S11 family
PSEFU_RS00690	COG2910	NAD(P)H-binding
PSEFU_RS00700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSEFU_RS00705	COG0159	tryptophan synthase activity
PSEFU_RS00710	COG0133	tryptophan synthase activity
PSEFU_RS00735	COG0622	Phosphoesterase
PSEFU_RS00740	COG0129	dihydroxy-acid dehydratase activity
PSEFU_RS00745	COG2201	protein-glutamate methylesterase activity
PSEFU_RS00750	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PSEFU_RS00760	COG0835	chemotaxis
PSEFU_RS00765	COG0840	transmembrane signaling receptor activity
PSEFU_RS00775	COG0643	Histidine kinase
PSEFU_RS00775	COG2198	Histidine kinase
PSEFU_RS00790	COG0840	transmembrane signaling receptor activity
PSEFU_RS00795	COG2197	response regulator
PSEFU_RS00800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSEFU_RS00805	COG0693	protein deglycase activity
PSEFU_RS00815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSEFU_RS00830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PSEFU_RS00835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PSEFU_RS00850	COG0429	hydrolase of the alpha beta-hydrolase fold
PSEFU_RS00855	COG0742	ribosomal rna small subunit methyltransferase
PSEFU_RS00860	COG0612	Peptidase, M16
PSEFU_RS00865	COG0612	Peptidase, M16
PSEFU_RS00870	COG0552	protein localization to endoplasmic reticulum
PSEFU_RS00875	COG2884	Cell division ATP-binding protein ftsE
PSEFU_RS00880	COG2177	Part of the ABC transporter FtsEX involved in
PSEFU_RS00890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PSEFU_RS00895	COG2363	Small membrane protein
PSEFU_RS00905	COG2022	thiamine diphosphate biosynthetic process
PSEFU_RS00910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PSEFU_RS00925	COG0708	Exodeoxyribonuclease III
PSEFU_RS00940	COG1607	acyl-coa hydrolase
PSEFU_RS00950	COG0573	inorganic phosphate transmembrane transporter activity
PSEFU_RS00955	COG0573	inorganic phosphate transmembrane transporter activity
PSEFU_RS00960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSEFU_RS00975	COG0415	Belongs to the DNA photolyase family
PSEFU_RS00980	COG2095	MarC family integral membrane protein
PSEFU_RS00985	COG3023	N-Acetylmuramoyl-L-alanine amidase
PSEFU_RS00990	COG5002	protein histidine kinase activity
PSEFU_RS00995	COG2204	response regulator
PSEFU_RS01025	COG0700	Nucleoside recognition
PSEFU_RS01035	COG0583	DNA-binding transcription factor activity
PSEFU_RS01040	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS01045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSEFU_RS01060	COG3604	Transcriptional regulator
PSEFU_RS01130	COG0174	glutamine synthetase
PSEFU_RS01135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS01140	COG2233	PERMEase
PSEFU_RS01145	COG4521	taurine ABC transporter
PSEFU_RS01155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSEFU_RS01160	COG2175	clavaminate synthase activity
PSEFU_RS01165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSEFU_RS01170	COG3360	Dodecin
PSEFU_RS01180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSEFU_RS01185	COG1764	response to oxidative stress
PSEFU_RS01305	COG0631	protein serine/threonine phosphatase activity
PSEFU_RS01310	COG0515	serine threonine protein kinase
PSEFU_RS01310	COG2815	serine threonine protein kinase
PSEFU_RS01355	COG0739	heme binding
PSEFU_RS01370	COG1253	flavin adenine dinucleotide binding
PSEFU_RS01385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PSEFU_RS01390	COG3161	chorismate lyase activity
PSEFU_RS01420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PSEFU_RS01425	COG0583	DNA-binding transcription factor activity
PSEFU_RS01435	COG0848	biopolymer transport protein
PSEFU_RS01445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSEFU_RS01455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PSEFU_RS01460	COG1758	RNA polymerase activity
PSEFU_RS01470	COG1561	YicC-like family, N-terminal region
PSEFU_RS01475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PSEFU_RS01495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PSEFU_RS01500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PSEFU_RS01510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSEFU_RS01510	COG2813	Specifically methylates the guanine in position
PSEFU_RS01515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSEFU_RS01525	COG1872	DUF167
PSEFU_RS01580	COG0540	Belongs to the ATCase OTCase family
PSEFU_RS01585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PSEFU_RS01635	COG0784	Response regulator, receiver
PSEFU_RS01635	COG0784	Response regulator, receiver
PSEFU_RS01635	COG0643	Histidine kinase
PSEFU_RS01635	COG2198	Histidine kinase
PSEFU_RS01635	COG0643	Histidine kinase
PSEFU_RS01635	COG2198	Histidine kinase
PSEFU_RS01655	COG3038	cytochrome b561
PSEFU_RS01660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PSEFU_RS01670	COG3038	cytochrome b561
PSEFU_RS01675	COG2353	YceI-like domain
PSEFU_RS01680	COG0513	Belongs to the DEAD box helicase family
PSEFU_RS01685	COG2375	cellular response to nickel ion
PSEFU_RS01690	COG1611	Belongs to the LOG family
PSEFU_RS01695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PSEFU_RS01700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PSEFU_RS01710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PSEFU_RS01720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PSEFU_RS01725	COG2226	methyltransferase
PSEFU_RS01730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PSEFU_RS01740	COG0126	phosphoglycerate kinase activity
PSEFU_RS01765	COG2133	pyrroloquinoline quinone binding
PSEFU_RS01770	COG1451	nucleotide metabolic process
PSEFU_RS01775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSEFU_RS01780	COG1289	transmembrane transporter activity
PSEFU_RS01785	COG0625	glutathione transferase activity
PSEFU_RS01800	COG2199	diguanylate cyclase activity
PSEFU_RS01810	COG2957	Belongs to the agmatine deiminase family
PSEFU_RS01820	COG0174	glutamine synthetase
PSEFU_RS01825	COG0174	glutamine synthetase
PSEFU_RS01845	COG3842	ATPase activity
PSEFU_RS01850	COG1176	ABC-type spermidine putrescine transport system, permease component I
PSEFU_RS01855	COG1177	transmembrane transport
PSEFU_RS01860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PSEFU_RS01875	COG0347	Belongs to the P(II) protein family
PSEFU_RS01880	COG0004	ammonium transporteR
PSEFU_RS01885	COG0004	ammonium transporteR
PSEFU_RS01890	COG0432	Pfam Uncharacterised protein family UPF0047
PSEFU_RS01900	COG1011	Hydrolase
PSEFU_RS01905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PSEFU_RS01915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PSEFU_RS01925	COG1965	Belongs to the frataxin family
PSEFU_RS01935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSEFU_RS01960	COG1414	Transcriptional regulator
PSEFU_RS01965	COG0800	Aldolase
PSEFU_RS01975	COG0625	glutathione transferase activity
PSEFU_RS01990	COG0165	Argininosuccinate lyase
PSEFU_RS01995	COG3275	phosphorelay sensor kinase activity
PSEFU_RS02005	COG0181	hydroxymethylbilane synthase activity
PSEFU_RS02065	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PSEFU_RS02080	COG0018	arginyl-trna synthetase
PSEFU_RS02085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PSEFU_RS02090	COG0254	rRNA binding
PSEFU_RS02105	COG0281	malic enzyme
PSEFU_RS02140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PSEFU_RS02145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PSEFU_RS02155	COG0070	glutamate synthase
PSEFU_RS02155	COG0069	glutamate synthase activity
PSEFU_RS02155	COG0067	glutamate synthase
PSEFU_RS02160	COG0493	'glutamate synthase
PSEFU_RS02180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSEFU_RS02215	COG1131	(ABC) transporter
PSEFU_RS02245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSEFU_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS02270	COG2226	methyltransferase
PSEFU_RS02300	COG2986	histidine ammonia-lyase
PSEFU_RS02325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSEFU_RS02330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSEFU_RS02345	COG1192	Involved in chromosome partitioning
PSEFU_RS02355	COG3118	belongs to the thioredoxin family
PSEFU_RS02365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PSEFU_RS02370	COG1944	ATP diphosphatase activity
PSEFU_RS02380	COG1794	racemase activity, acting on amino acids and derivatives
PSEFU_RS02400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PSEFU_RS02405	COG3264	Mechanosensitive ion channel
PSEFU_RS02405	COG1196	nuclear chromosome segregation
PSEFU_RS02410	COG3263	regulation of cellular component size
PSEFU_RS02415	COG0248	Ppx GppA phosphatase
PSEFU_RS02430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PSEFU_RS02455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PSEFU_RS02470	COG3079	Belongs to the UPF0149 family
PSEFU_RS02475	COG0006	proline dipeptidase activity
PSEFU_RS02480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSEFU_RS02490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSEFU_RS02500	COG1178	ABC-type Fe3 transport system permease component
PSEFU_RS02525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PSEFU_RS02540	COG1392	Phosphate transport regulator
PSEFU_RS02545	COG0306	phosphate transporter
PSEFU_RS02555	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PSEFU_RS02555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PSEFU_RS02570	COG2252	PERMEase
PSEFU_RS02575	COG0443	Heat shock 70 kDa protein
PSEFU_RS02605	COG0784	Response regulator, receiver
PSEFU_RS02605	COG4191	Histidine kinase
PSEFU_RS02610	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS02615	COG4251	negative regulation of phosphorylation
PSEFU_RS02620	COG3204	pilus organization
PSEFU_RS02635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSEFU_RS02655	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS02660	COG0183	Belongs to the thiolase family
PSEFU_RS02665	COG2169	Transcriptional regulator
PSEFU_RS02665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSEFU_RS02675	COG2146	nitrite reductase [NAD(P)H] activity
PSEFU_RS02675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSEFU_RS02680	COG2146	nitrite reductase [NAD(P)H] activity
PSEFU_RS02680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSEFU_RS02685	COG2116	formate transmembrane transporter activity
PSEFU_RS02690	COG0515	serine threonine protein kinase
PSEFU_RS02695	COG1253	flavin adenine dinucleotide binding
PSEFU_RS02705	COG0840	transmembrane signaling receptor activity
PSEFU_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSEFU_RS02740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSEFU_RS02750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PSEFU_RS02815	COG0784	Response regulator, receiver
PSEFU_RS02815	COG4191	Histidine kinase
PSEFU_RS02845	COG4215	(ABC) transporter
PSEFU_RS02870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PSEFU_RS02880	COG3850	Histidine kinase
PSEFU_RS02880	COG4999	Histidine kinase
PSEFU_RS02880	COG2205	protein histidine kinase activity
PSEFU_RS02880	COG3437	response regulator, receiver
PSEFU_RS02895	COG4770	biotin carboxylase activity
PSEFU_RS02900	COG1984	allophanate hydrolase subunit 2
PSEFU_RS02905	COG4336	lyase activity
PSEFU_RS02910	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PSEFU_RS02915	COG1914	H( )-stimulated, divalent metal cation uptake system
PSEFU_RS02930	COG1476	TRANSCRIPTIONal
PSEFU_RS02960	COG0456	acetyltransferase
PSEFU_RS02970	COG0512	Glutamine amidotransferase of anthranilate synthase
PSEFU_RS02975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSEFU_RS02980	COG0134	indole-3-glycerol-phosphate synthase activity
PSEFU_RS02995	COG3023	N-Acetylmuramoyl-L-alanine amidase
PSEFU_RS03005	COG0084	hydrolase, TatD family'
PSEFU_RS03010	COG2982	Protein involved in outer membrane biogenesis
PSEFU_RS03020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSEFU_RS03020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSEFU_RS03025	COG1105	Belongs to the carbohydrate kinase PfkB family
PSEFU_RS03030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PSEFU_RS03030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PSEFU_RS03030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PSEFU_RS03040	COG1765	OsmC-like protein
PSEFU_RS03045	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PSEFU_RS03055	COG4221	oxidoreductase activity
PSEFU_RS03065	COG1981	membrane
PSEFU_RS03080	COG0316	Belongs to the HesB IscA family
PSEFU_RS03085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PSEFU_RS03090	COG0739	heme binding
PSEFU_RS03095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PSEFU_RS03125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PSEFU_RS03125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PSEFU_RS03130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PSEFU_RS03155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PSEFU_RS03175	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PSEFU_RS03180	COG0081	regulation of translation
PSEFU_RS03185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PSEFU_RS03190	COG0222	ribosome binding
PSEFU_RS03195	COG0085	RNA polymerase activity
PSEFU_RS03200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PSEFU_RS03205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PSEFU_RS03210	COG0049	tRNA binding
PSEFU_RS03215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PSEFU_RS03220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PSEFU_RS03225	COG0051	transcription antitermination factor activity, RNA binding
PSEFU_RS03230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PSEFU_RS03235	COG0088	Forms part of the polypeptide exit tunnel
PSEFU_RS03240	COG0089	rRNA binding
PSEFU_RS03245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PSEFU_RS03250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PSEFU_RS03255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PSEFU_RS03260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PSEFU_RS03265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PSEFU_RS03270	COG0255	Belongs to the universal ribosomal protein uL29 family
PSEFU_RS03275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PSEFU_RS03280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PSEFU_RS03285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PSEFU_RS03290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PSEFU_RS03295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PSEFU_RS03300	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PSEFU_RS03305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PSEFU_RS03310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PSEFU_RS03315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PSEFU_RS03320	COG1841	ribosomal large subunit assembly
PSEFU_RS03325	COG0200	Binds to the 23S rRNA
PSEFU_RS03335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PSEFU_RS03340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PSEFU_RS03345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PSEFU_RS03350	COG0202	RNA polymerase activity
PSEFU_RS03355	COG0203	ribosomal protein L17
PSEFU_RS03360	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PSEFU_RS03370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PSEFU_RS03375	COG2814	Major facilitator Superfamily
PSEFU_RS03380	COG0629	single-stranded DNA binding
PSEFU_RS03400	COG3047	cAMP biosynthetic process
PSEFU_RS03430	COG3118	belongs to the thioredoxin family
PSEFU_RS03435	COG2264	protein methyltransferase activity
PSEFU_RS03445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSEFU_RS03450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSEFU_RS03450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSEFU_RS03455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PSEFU_RS03470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PSEFU_RS03485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PSEFU_RS03495	COG3577	Aspartyl protease
PSEFU_RS03530	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS03535	COG2814	Major facilitator Superfamily
PSEFU_RS03540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSEFU_RS03545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSEFU_RS03555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS03570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS03580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PSEFU_RS03585	COG1917	Cupin 2, conserved barrel domain protein
PSEFU_RS03595	COG0427	acetyl-CoA hydrolase
PSEFU_RS03610	COG0210	DNA helicase
PSEFU_RS03620	COG0534	Mate efflux family protein
PSEFU_RS03625	COG0583	DNA-binding transcription factor activity
PSEFU_RS03630	COG0840	transmembrane signaling receptor activity
PSEFU_RS03635	COG0019	diaminopimelate decarboxylase activity
PSEFU_RS03640	COG1067	ATP-dependent peptidase activity
PSEFU_RS03650	COG2862	Uncharacterized protein family, UPF0114
PSEFU_RS03660	COG0545	Peptidyl-prolyl cis-trans isomerase
PSEFU_RS03670	COG0142	geranyltranstransferase activity
PSEFU_RS03675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PSEFU_RS03680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PSEFU_RS03685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PSEFU_RS03690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PSEFU_RS03695	COG3045	CreA protein
PSEFU_RS03705	COG0268	Binds directly to 16S ribosomal RNA
PSEFU_RS03715	COG0196	riboflavin kinase activity
PSEFU_RS03720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PSEFU_RS03725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PSEFU_RS03730	COG1047	Peptidyl-prolyl cis-trans
PSEFU_RS03745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PSEFU_RS03760	COG3228	Belongs to the MtfA family
PSEFU_RS03765	COG0456	acetyltransferase
PSEFU_RS03770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PSEFU_RS03785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSEFU_RS03790	COG1739	Uncharacterized protein family UPF0029
PSEFU_RS03795	COG1309	transcriptional regulator
PSEFU_RS03800	COG0667	Aldo Keto reductase
PSEFU_RS03845	COG0683	leucine binding
PSEFU_RS03895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PSEFU_RS03905	COG1515	deoxyribonuclease V activity
PSEFU_RS03910	COG0667	Aldo Keto reductase
PSEFU_RS03915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PSEFU_RS03920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PSEFU_RS03925	COG0723	plastoquinol--plastocyanin reductase activity
PSEFU_RS03930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PSEFU_RS03935	COG2857	Cytochrome c1
PSEFU_RS03940	COG0625	glutathione transferase activity
PSEFU_RS03945	COG2969	positive regulation of protein catabolic process
PSEFU_RS03970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSEFU_RS03975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PSEFU_RS04005	COG0765	amino acid transport
PSEFU_RS04025	COG2814	Major facilitator Superfamily
PSEFU_RS04045	COG2205	protein histidine kinase activity
PSEFU_RS04070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSEFU_RS04075	COG0601	transmembrane transport
PSEFU_RS04080	COG0747	negative chemotaxis
PSEFU_RS04130	COG4221	oxidoreductase activity
PSEFU_RS04135	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
PSEFU_RS04140	COG2814	Major facilitator Superfamily
PSEFU_RS04150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PSEFU_RS04160	COG1643	Atp-dependent helicase
PSEFU_RS04170	COG1609	Transcriptional regulator
PSEFU_RS04190	COG0513	Belongs to the DEAD box helicase family
PSEFU_RS04205	COG0123	including yeast histone deacetylase and acetoin utilization protein
PSEFU_RS04215	COG1946	Acyl-CoA thioesterase
PSEFU_RS04280	COG2814	Major facilitator Superfamily
PSEFU_RS04305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PSEFU_RS04315	COG3098	single-species biofilm formation
PSEFU_RS04325	COG0028	Belongs to the TPP enzyme family
PSEFU_RS04340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PSEFU_RS04345	COG1183	phosphatidylcholine synthase activity
PSEFU_RS04350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSEFU_RS04355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PSEFU_RS04385	COG2995	paraquat-inducible protein a
PSEFU_RS04390	COG2995	paraquat-inducible protein a
PSEFU_RS04395	COG3008	intermembrane lipid transfer
PSEFU_RS04415	COG0019	diaminopimelate decarboxylase activity
PSEFU_RS04430	COG2706	6-phosphogluconolactonase activity
PSEFU_RS04435	COG2851	Citrate transporter
PSEFU_RS04450	COG0583	DNA-binding transcription factor activity
PSEFU_RS04460	COG0456	acetyltransferase
PSEFU_RS04470	COG0288	reversible hydration of carbon dioxide
PSEFU_RS04480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PSEFU_RS04490	COG2824	Alkylphosphonate utilization operon protein PhnA
PSEFU_RS04500	COG1295	ribonuclease BN
PSEFU_RS04520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSEFU_RS04535	COG0586	Pfam SNARE associated Golgi protein
PSEFU_RS04565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PSEFU_RS04575	COG1335	isochorismatase
PSEFU_RS04600	COG2197	response regulator
PSEFU_RS04605	COG4585	Histidine kinase
PSEFU_RS04630	COG3706	GGDEF domain
PSEFU_RS04640	COG0193	aminoacyl-tRNA hydrolase activity
PSEFU_RS04645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PSEFU_RS04650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PSEFU_RS04665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PSEFU_RS04670	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PSEFU_RS04680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PSEFU_RS04685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PSEFU_RS04695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PSEFU_RS04700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PSEFU_RS04720	COG4221	oxidoreductase activity
PSEFU_RS04725	COG0415	Belongs to the DNA photolyase family
PSEFU_RS04730	COG0789	Transcriptional regulator
PSEFU_RS04745	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PSEFU_RS04750	COG1090	epimerase
PSEFU_RS04755	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PSEFU_RS04765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PSEFU_RS04770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PSEFU_RS04775	COG0659	secondary active sulfate transmembrane transporter activity
PSEFU_RS04805	COG0116	Belongs to the methyltransferase superfamily
PSEFU_RS04805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSEFU_RS04820	COG0166	Belongs to the GPI family
PSEFU_RS04825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PSEFU_RS04830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PSEFU_RS04840	COG0617	tRNA 3'-terminal CCA addition
PSEFU_RS04850	COG4191	Histidine kinase
PSEFU_RS04860	COG2308	Evidence 4 Homologs of previously reported genes of
PSEFU_RS04880	COG0714	Associated with various cellular activities
PSEFU_RS04910	COG2925	Exonuclease
PSEFU_RS04920	COG0788	formyltetrahydrofolate deformylase activity
PSEFU_RS04925	COG0517	IMP dehydrogenase activity
PSEFU_RS04925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSEFU_RS04925	COG0617	tRNA 3'-terminal CCA addition
PSEFU_RS04935	COG0433	COG0433 Predicted ATPase
PSEFU_RS04945	COG2017	converts alpha-aldose to the beta-anomer
PSEFU_RS04980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSEFU_RS04985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSEFU_RS05010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSEFU_RS05015	COG1609	Transcriptional regulator
PSEFU_RS05025	COG2271	Major facilitator Superfamily
PSEFU_RS05030	COG2721	sulfolactate sulfo-lyase activity
PSEFU_RS05035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSEFU_RS05040	COG1802	Transcriptional regulator
PSEFU_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS05060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSEFU_RS05075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS05085	COG0174	glutamine synthetase
PSEFU_RS05105	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PSEFU_RS05115	COG1845	cytochrome c oxidase, subunit III
PSEFU_RS05120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PSEFU_RS05135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSEFU_RS05150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSEFU_RS05155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSEFU_RS05155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSEFU_RS05180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSEFU_RS05200	COG0300	oxidoreductase activity
PSEFU_RS05210	COG3022	response to hydroperoxide
PSEFU_RS05215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PSEFU_RS05220	COG0315	cyclic pyranopterin monophosphate synthase activity
PSEFU_RS05235	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PSEFU_RS05240	COG4536	flavin adenine dinucleotide binding
PSEFU_RS05250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PSEFU_RS05255	COG0228	four-way junction DNA binding
PSEFU_RS05260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PSEFU_RS05265	COG0336	Belongs to the RNA methyltransferase TrmD family
PSEFU_RS05270	COG0335	large ribosomal subunit rRNA binding
PSEFU_RS05280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PSEFU_RS05305	COG1842	Phage shock protein A
PSEFU_RS05360	COG0400	carboxylic ester hydrolase activity
PSEFU_RS05365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSEFU_RS05370	COG4597	amino acid ABC transporter
PSEFU_RS05375	COG0765	amino acid transport
PSEFU_RS05380	COG1126	abc transporter atp-binding protein
PSEFU_RS05395	COG0477	Major facilitator Superfamily
PSEFU_RS05415	COG2827	Endonuclease containing a URI domain
PSEFU_RS05425	COG4302	ethanolamine ammonia-lyase activity
PSEFU_RS05430	COG4303	Ethanolamine ammonia lyase large subunit
PSEFU_RS05435	COG0531	amino acid
PSEFU_RS05455	COG0583	DNA-binding transcription factor activity
PSEFU_RS05475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSEFU_RS05490	COG1397	ADP-ribosylglycohydrolase
PSEFU_RS05495	COG0247	lactate metabolic process
PSEFU_RS05495	COG0277	FAD linked oxidase domain protein
PSEFU_RS05510	COG2271	Major facilitator Superfamily
PSEFU_RS05515	COG2721	sulfolactate sulfo-lyase activity
PSEFU_RS05520	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS05530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSEFU_RS05535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSEFU_RS05540	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS05560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSEFU_RS05565	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS05570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSEFU_RS05575	COG0596	Alpha beta hydrolase
PSEFU_RS05585	COG4175	Glycine betaine
PSEFU_RS05590	COG4176	ABC-type proline glycine betaine transport system permease component
PSEFU_RS05600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSEFU_RS05610	COG0583	DNA-binding transcription factor activity
PSEFU_RS05615	COG0066	3-isopropylmalate dehydratase activity
PSEFU_RS05620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PSEFU_RS05635	COG3081	Nucleoid-associated protein
PSEFU_RS05645	COG0531	amino acid
PSEFU_RS05650	COG1522	sequence-specific DNA binding
PSEFU_RS05670	COG0642	Histidine kinase
PSEFU_RS05680	COG1368	sulfuric ester hydrolase activity
PSEFU_RS05710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSEFU_RS05720	COG2264	protein methyltransferase activity
PSEFU_RS05725	COG0420	3'-5' exonuclease activity
PSEFU_RS05730	COG0840	transmembrane signaling receptor activity
PSEFU_RS05735	COG2188	Transcriptional regulator
PSEFU_RS05750	COG2133	pyrroloquinoline quinone binding
PSEFU_RS05755	COG0419	ATPase involved in DNA repair
PSEFU_RS05765	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PSEFU_RS05775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PSEFU_RS05785	COG0840	transmembrane signaling receptor activity
PSEFU_RS05815	COG5001	Diguanylate cyclase
PSEFU_RS05815	COG4251	negative regulation of phosphorylation
PSEFU_RS05815	COG3706	GGDEF domain
PSEFU_RS05815	COG2203	Gaf domain
PSEFU_RS05835	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PSEFU_RS05870	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PSEFU_RS05875	COG0563	adenylate kinase activity
PSEFU_RS05895	COG1801	Protein of unknown function DUF72
PSEFU_RS05925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PSEFU_RS05935	COG1279	arginine transmembrane transporter activity
PSEFU_RS05940	COG0583	DNA-binding transcription factor activity
PSEFU_RS05945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSEFU_RS05955	COG1902	pentaerythritol trinitrate reductase activity
PSEFU_RS06000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSEFU_RS06005	COG0784	Response regulator, receiver
PSEFU_RS06005	COG4191	Histidine kinase
PSEFU_RS06015	COG4191	Histidine kinase
PSEFU_RS06015	COG0784	Response regulator, receiver
PSEFU_RS06020	COG0784	Response regulator, receiver
PSEFU_RS06020	COG4191	Histidine kinase
PSEFU_RS06075	COG2223	nitrite transmembrane transporter activity
PSEFU_RS06085	COG4251	negative regulation of phosphorylation
PSEFU_RS06085	COG3706	GGDEF domain
PSEFU_RS06085	COG2203	Gaf domain
PSEFU_RS06085	COG5001	Diguanylate cyclase
PSEFU_RS06090	COG0583	DNA-binding transcription factor activity
PSEFU_RS06105	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSEFU_RS06110	COG0174	glutamine synthetase
PSEFU_RS06150	COG2207	Transcriptional regulator
PSEFU_RS06170	COG0494	nUDIX hydrolase
PSEFU_RS06200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSEFU_RS06205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSEFU_RS06210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PSEFU_RS06215	COG0583	DNA-binding transcription factor activity
PSEFU_RS06220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PSEFU_RS06235	COG2271	Major facilitator Superfamily
PSEFU_RS06240	COG1609	Transcriptional regulator
PSEFU_RS06245	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS06255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSEFU_RS06270	COG0210	DNA helicase
PSEFU_RS06285	COG3180	Ammonia monooxygenase
PSEFU_RS06290	COG0583	DNA-binding transcription factor activity
PSEFU_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS06325	COG0640	Transcriptional regulator
PSEFU_RS06330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSEFU_RS06335	COG0431	NADPH-dependent FMN reductase
PSEFU_RS06340	COG1247	-acetyltransferase
PSEFU_RS06350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSEFU_RS06375	COG2828	Protein conserved in bacteria
PSEFU_RS06395	COG0583	DNA-binding transcription factor activity
PSEFU_RS06405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS06410	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS06415	COG0583	DNA-binding transcription factor activity
PSEFU_RS06420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSEFU_RS06425	COG5383	Protein conserved in bacteria
PSEFU_RS06440	COG0306	phosphate transporter
PSEFU_RS06445	COG3038	cytochrome b561
PSEFU_RS06465	COG4221	oxidoreductase activity
PSEFU_RS06520	COG1024	Enoyl-CoA hydratase
PSEFU_RS06530	COG1116	anion transmembrane transporter activity
PSEFU_RS06535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSEFU_RS06550	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSEFU_RS06550	COG1024	Enoyl-CoA hydratase
PSEFU_RS06565	COG0662	Cupin 2, conserved barrel domain protein
PSEFU_RS06580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS06595	COG1335	isochorismatase
PSEFU_RS06630	COG3706	GGDEF domain
PSEFU_RS06640	COG0469	pyruvate kinase activity
PSEFU_RS06675	COG1546	Belongs to the CinA family
PSEFU_RS06685	COG2137	regulation of response to DNA damage stimulus
PSEFU_RS06700	COG3148	PFAM DTW domain containing protein
PSEFU_RS06720	COG0583	DNA-binding transcription factor activity
PSEFU_RS06745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PSEFU_RS06750	COG0418	dihydroorotase activity
PSEFU_RS06760	COG0137	argininosuccinate synthase activity
PSEFU_RS06775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PSEFU_RS06795	COG0789	Transcriptional regulator
PSEFU_RS06805	COG1366	Belongs to the anti-sigma-factor antagonist family
PSEFU_RS06830	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PSEFU_RS06835	COG3052	prosthetic group binding
PSEFU_RS06885	COG1131	(ABC) transporter
PSEFU_RS06890	COG0842	Transport permease protein
PSEFU_RS06895	COG0494	nUDIX hydrolase
PSEFU_RS06915	COG3189	MarR family transcriptional regulator
PSEFU_RS06930	COG0583	DNA-binding transcription factor activity
PSEFU_RS06950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PSEFU_RS06950	COG0519	Catalyzes the synthesis of GMP from XMP
PSEFU_RS06955	COG5001	Diguanylate cyclase
PSEFU_RS06960	COG2860	membrane
PSEFU_RS06975	COG2249	NAD(P)H dehydrogenase (quinone) activity
PSEFU_RS06980	COG1840	ABC-type Fe3 transport system, periplasmic component
PSEFU_RS06985	COG1178	ABC-type Fe3 transport system permease component
PSEFU_RS06990	COG2132	Multicopper oxidase
PSEFU_RS06995	COG0590	tRNA wobble adenosine to inosine editing
PSEFU_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS07015	COG0583	DNA-binding transcription factor activity
PSEFU_RS07020	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PSEFU_RS07025	COG0047	phosphoribosylformylglycinamidine synthase activity
PSEFU_RS07025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSEFU_RS07035	COG3034	peptidoglycan biosynthetic process
PSEFU_RS07040	COG1741	Belongs to the pirin family
PSEFU_RS07045	COG0583	DNA-binding transcription factor activity
PSEFU_RS07050	COG0436	Aminotransferase
PSEFU_RS07055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSEFU_RS07060	COG1064	alcohol dehydrogenase
PSEFU_RS07070	COG0174	glutamine synthetase
PSEFU_RS07075	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS07080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS07095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSEFU_RS07100	COG0668	transmembrane transport
PSEFU_RS07105	COG0625	glutathione transferase activity
PSEFU_RS07110	COG0739	heme binding
PSEFU_RS07115	COG1570	exodeoxyribonuclease VII activity
PSEFU_RS07120	COG0583	DNA-binding transcription factor activity
PSEFU_RS07155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PSEFU_RS07180	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PSEFU_RS07195	COG5532	Uncharacterized conserved protein (DUF2303)
PSEFU_RS07235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSEFU_RS07420	COG2135	peptidase activity
PSEFU_RS07425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSEFU_RS07435	COG2031	fatty acid transporter
PSEFU_RS07445	COG0392	lysyltransferase activity
PSEFU_RS07445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PSEFU_RS07465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PSEFU_RS07485	COG2205	protein histidine kinase activity
PSEFU_RS07485	COG5002	protein histidine kinase activity
PSEFU_RS07485	COG0784	Response regulator, receiver
PSEFU_RS07505	COG0500	methyltransferase
PSEFU_RS07510	COG2819	hydrolase of the alpha beta superfamily
PSEFU_RS07520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSEFU_RS07525	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSEFU_RS07530	COG1120	ATPase activity
PSEFU_RS07540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PSEFU_RS07545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PSEFU_RS07550	COG3956	TIGRFAM MazG family protein
PSEFU_RS07555	COG3122	Protein conserved in bacteria
PSEFU_RS07570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PSEFU_RS07575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PSEFU_RS07585	COG0628	permease
PSEFU_RS07605	COG1393	Belongs to the ArsC family
PSEFU_RS07610	COG1295	ribonuclease BN
PSEFU_RS07645	COG0442	prolyl-tRNA aminoacylation
PSEFU_RS07660	COG2900	Belongs to the SlyX family
PSEFU_RS07680	COG0783	Belongs to the Dps family
PSEFU_RS07685	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PSEFU_RS07695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PSEFU_RS07700	COG0632	four-way junction helicase activity
PSEFU_RS07705	COG2255	four-way junction helicase activity
PSEFU_RS07710	COG0824	Thioesterase
PSEFU_RS07735	COG2885	chlorophyll binding
PSEFU_RS07740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PSEFU_RS07745	COG0602	queuosine metabolic process
PSEFU_RS07750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PSEFU_RS07760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PSEFU_RS07775	COG0425	Belongs to the sulfur carrier protein TusA family
PSEFU_RS07780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PSEFU_RS07790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSEFU_RS07795	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PSEFU_RS07800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PSEFU_RS07825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSEFU_RS07830	COG4628	conserved protein (DUF2132)
PSEFU_RS07840	COG0656	L-ascorbic acid biosynthetic process
PSEFU_RS07845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSEFU_RS07865	COG1289	transmembrane transporter activity
PSEFU_RS07880	COG0402	S-adenosylhomocysteine deaminase activity
PSEFU_RS07885	COG3835	regulator
PSEFU_RS07890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PSEFU_RS07900	COG2030	dehydratase
PSEFU_RS07905	COG2267	carboxylic ester hydrolase activity
PSEFU_RS07910	COG0318	PFAM AMP-dependent synthetase and ligase
PSEFU_RS07915	COG0318	PFAM AMP-dependent synthetase and ligase
PSEFU_RS07920	COG4294	response to UV
PSEFU_RS07925	COG3639	organic phosphonate transmembrane transporter activity
PSEFU_RS07930	COG3639	organic phosphonate transmembrane transporter activity
PSEFU_RS07935	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PSEFU_RS07940	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PSEFU_RS07945	COG0709	Synthesizes selenophosphate from selenide and ATP
PSEFU_RS07950	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PSEFU_RS07955	COG1943	Transposase
PSEFU_RS07960	COG2807	transmembrane transport
PSEFU_RS07970	COG1846	Transcriptional regulator
PSEFU_RS07990	COG0583	DNA-binding transcription factor activity
PSEFU_RS07995	COG2814	Major facilitator Superfamily
PSEFU_RS08010	COG2814	Major facilitator Superfamily
PSEFU_RS08015	COG0640	Transcriptional regulator
PSEFU_RS08075	COG0531	amino acid
PSEFU_RS08085	COG1643	Atp-dependent helicase
PSEFU_RS08100	COG4178	(ABC) transporter
PSEFU_RS08105	COG0243	molybdopterin cofactor binding
PSEFU_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS08140	COG0840	transmembrane signaling receptor activity
PSEFU_RS08150	COG1609	Transcriptional regulator
PSEFU_RS08160	COG1056	cytidyltransferase-related domain
PSEFU_RS08160	COG3172	ATPase kinase involved in NAD metabolism
PSEFU_RS08165	COG1063	alcohol dehydrogenase
PSEFU_RS08175	COG3685	Protein conserved in bacteria
PSEFU_RS08185	COG1999	signal sequence binding
PSEFU_RS08195	COG0840	transmembrane signaling receptor activity
PSEFU_RS08200	COG1366	Belongs to the anti-sigma-factor antagonist family
PSEFU_RS08205	COG1366	Belongs to the anti-sigma-factor antagonist family
PSEFU_RS08210	COG2172	sigma factor antagonist activity
PSEFU_RS08220	COG2205	protein histidine kinase activity
PSEFU_RS08225	COG4191	Histidine kinase
PSEFU_RS08225	COG0784	Response regulator, receiver
PSEFU_RS08230	COG0840	transmembrane signaling receptor activity
PSEFU_RS08235	COG4191	Histidine kinase
PSEFU_RS08235	COG0784	Response regulator, receiver
PSEFU_RS08240	COG0494	nUDIX hydrolase
PSEFU_RS08265	COG0784	Response regulator, receiver
PSEFU_RS08265	COG4191	Histidine kinase
PSEFU_RS08270	COG5001	Diguanylate cyclase
PSEFU_RS08270	COG3300	MHYT domain
PSEFU_RS08275	COG1280	lysine exporter protein (LysE YggA)
PSEFU_RS08280	COG1115	amino acid carrier protein
PSEFU_RS08290	COG1733	regulation of RNA biosynthetic process
PSEFU_RS08300	COG0659	secondary active sulfate transmembrane transporter activity
PSEFU_RS08305	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PSEFU_RS08310	COG0673	inositol 2-dehydrogenase activity
PSEFU_RS08320	COG0840	transmembrane signaling receptor activity
PSEFU_RS08325	COG0840	transmembrane signaling receptor activity
PSEFU_RS08345	COG1968	undecaprenyl-diphosphatase activity
PSEFU_RS08350	COG0477	Major facilitator Superfamily
PSEFU_RS08355	COG0537	adenosine 5'-monophosphoramidase activity
PSEFU_RS08370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSEFU_RS08375	COG2814	Major facilitator Superfamily
PSEFU_RS08400	COG2866	Carboxypeptidase
PSEFU_RS08420	COG4191	Histidine kinase
PSEFU_RS08420	COG0784	Response regulator, receiver
PSEFU_RS08425	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PSEFU_RS08430	COG2204	response regulator
PSEFU_RS08455	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PSEFU_RS08485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSEFU_RS08520	COG1596	polysaccharide export
PSEFU_RS08530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSEFU_RS08555	COG2828	Protein conserved in bacteria
PSEFU_RS08560	COG0583	DNA-binding transcription factor activity
PSEFU_RS08565	COG2828	Protein conserved in bacteria
PSEFU_RS08570	COG1301	dicarboxylic acid transport
PSEFU_RS08575	COG2851	Citrate transporter
PSEFU_RS08600	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS08605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PSEFU_RS08610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PSEFU_RS08645	COG1560	Kdo2-lipid A biosynthetic process
PSEFU_RS08655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PSEFU_RS08660	COG1476	TRANSCRIPTIONal
PSEFU_RS08675	COG0730	response to heat
PSEFU_RS08680	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
PSEFU_RS08690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PSEFU_RS08715	COG1129	ABC transporter
PSEFU_RS08720	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSEFU_RS08725	COG1609	Transcriptional regulator
PSEFU_RS08730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSEFU_RS08735	COG1869	D-ribose catabolic process
PSEFU_RS08755	COG3842	ATPase activity
PSEFU_RS08785	COG2814	Major facilitator Superfamily
PSEFU_RS08795	COG2249	NAD(P)H dehydrogenase (quinone) activity
PSEFU_RS08815	COG3011	Protein conserved in bacteria
PSEFU_RS08840	COG1522	sequence-specific DNA binding
PSEFU_RS08850	COG0826	peptidase U32
PSEFU_RS08855	COG3012	SEC-C Motif Domain Protein
PSEFU_RS08855	COG3318	Belongs to the UPF0149 family
PSEFU_RS08885	COG3416	Protein conserved in bacteria
PSEFU_RS08890	COG2199	diguanylate cyclase activity
PSEFU_RS08890	COG2203	Gaf domain
PSEFU_RS08900	COG2226	methyltransferase
PSEFU_RS08940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSEFU_RS08945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSEFU_RS08945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSEFU_RS08950	COG0564	pseudouridine synthase activity
PSEFU_RS08955	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PSEFU_RS08960	COG2894	cell division
PSEFU_RS08965	COG0850	regulation of cytokinetic process
PSEFU_RS08975	COG0583	DNA-binding transcription factor activity
PSEFU_RS08980	COG2814	Major facilitator Superfamily
PSEFU_RS08985	COG4991	sh3 domain protein
PSEFU_RS08990	COG0583	DNA-binding transcription factor activity
PSEFU_RS09000	COG4948	Mandelate Racemase Muconate Lactonizing
PSEFU_RS09005	COG1335	isochorismatase
PSEFU_RS09015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PSEFU_RS09020	COG0573	inorganic phosphate transmembrane transporter activity
PSEFU_RS09025	COG0581	inorganic phosphate transmembrane transporter activity
PSEFU_RS09030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSEFU_RS09060	COG1959	2 iron, 2 sulfur cluster binding
PSEFU_RS09080	COG1045	serine acetyltransferase
PSEFU_RS09095	COG1121	(ABC) transporter
PSEFU_RS09130	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSEFU_RS09130	COG1902	pentaerythritol trinitrate reductase activity
PSEFU_RS09150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PSEFU_RS09155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PSEFU_RS09160	COG0705	Rhomboid family
PSEFU_RS09165	COG3139	Protein of unknown function (DUF1315)
PSEFU_RS09175	COG0308	aminopeptidase N
PSEFU_RS09245	COG0714	Associated with various cellular activities
PSEFU_RS09250	COG0840	transmembrane signaling receptor activity
PSEFU_RS09275	COG0167	dihydroorotate dehydrogenase activity
PSEFU_RS09280	COG0116	Belongs to the methyltransferase superfamily
PSEFU_RS09280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PSEFU_RS09285	COG2027	D-alanyl-D-alanine carboxypeptidase
PSEFU_RS09290	COG3171	Protein conserved in bacteria
PSEFU_RS09305	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PSEFU_RS09320	COG4575	ribosome binding
PSEFU_RS09325	COG0004	ammonium transporteR
PSEFU_RS09340	COG0835	chemotaxis
PSEFU_RS09340	COG0784	Response regulator, receiver
PSEFU_RS09345	COG3091	SprT-like family
PSEFU_RS09360	COG2818	Glycosylase
PSEFU_RS09365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PSEFU_RS09370	COG0791	NLP P60 protein
PSEFU_RS09385	COG1797	cobyrinic acid a,c-diamide synthase activity
PSEFU_RS09390	COG0778	Nitroreductase
PSEFU_RS09405	COG1492	cobalamin metabolic process
PSEFU_RS09415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PSEFU_RS09425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PSEFU_RS09445	COG2067	long-chain fatty acid transport protein
PSEFU_RS09455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSEFU_RS09465	COG3100	YcgL domain-containing protein
PSEFU_RS09470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSEFU_RS09475	COG2983	Belongs to the UPF0260 family
PSEFU_RS09515	COG0121	glutamine amidotransferase
PSEFU_RS09545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PSEFU_RS09555	COG4772	TonB-dependent receptor
PSEFU_RS09560	COG0840	transmembrane signaling receptor activity
PSEFU_RS09575	COG2853	Lipoprotein
PSEFU_RS09595	COG1555	photosystem II stabilization
PSEFU_RS09600	COG1677	Flagellar hook-basal body complex protein FliE
PSEFU_RS09625	COG2882	bacterial-type flagellum organization
PSEFU_RS09690	COG2032	superoxide dismutase activity
PSEFU_RS09695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PSEFU_RS09720	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PSEFU_RS09725	COG0643	Histidine kinase
PSEFU_RS09725	COG0784	Response regulator, receiver
PSEFU_RS09725	COG2198	Histidine kinase
PSEFU_RS09735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PSEFU_RS09740	COG1360	Flagellar Motor Protein
PSEFU_RS09745	COG1192	Involved in chromosome partitioning
PSEFU_RS09755	COG0835	chemotaxis
PSEFU_RS09765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PSEFU_RS09795	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PSEFU_RS09800	COG1138	Cytochrome C-type biogenesis protein
PSEFU_RS09825	COG1414	Transcriptional regulator
PSEFU_RS09845	COG3089	Belongs to the UPF0270 family
PSEFU_RS09850	COG0776	regulation of translation
PSEFU_RS09865	COG1363	Peptidase, m42
PSEFU_RS09870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PSEFU_RS09870	COG0189	ligase activity
PSEFU_RS09875	COG0367	asparagine synthase
PSEFU_RS09885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS09885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PSEFU_RS09890	COG2326	polyphosphate kinase activity
PSEFU_RS09900	COG2832	Protein of unknown function (DUF454)
PSEFU_RS09910	COG0514	ATP-dependent DNA helicase (RecQ)
PSEFU_RS09920	COG2814	Major facilitator Superfamily
PSEFU_RS09935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSEFU_RS09940	COG2207	Transcriptional regulator
PSEFU_RS09965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PSEFU_RS09970	COG0727	PFAM Uncharacterised protein family (UPF0153)
PSEFU_RS09975	COG0778	Nitroreductase
PSEFU_RS09980	COG0642	Histidine kinase
PSEFU_RS09990	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS09995	COG2350	Protein conserved in bacteria
PSEFU_RS10000	COG0613	PHP domain protein
PSEFU_RS10005	COG0009	L-threonylcarbamoyladenylate synthase
PSEFU_RS10015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PSEFU_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS10045	COG0546	phosphoglycolate phosphatase activity
PSEFU_RS10050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PSEFU_RS10060	COG0402	S-adenosylhomocysteine deaminase activity
PSEFU_RS10065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PSEFU_RS10075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PSEFU_RS10085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PSEFU_RS10090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PSEFU_RS10095	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PSEFU_RS10125	COG2814	Major facilitator Superfamily
PSEFU_RS10130	COG3135	benzoate transporter
PSEFU_RS10145	COG4948	Mandelate Racemase Muconate Lactonizing
PSEFU_RS10150	COG4829	muconolactone delta-isomerase
PSEFU_RS10155	COG3485	protocatechuate 3,4-dioxygenase
PSEFU_RS10165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PSEFU_RS10170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PSEFU_RS10180	COG0477	Major facilitator Superfamily
PSEFU_RS10190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSEFU_RS10195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSEFU_RS10245	COG1289	transmembrane transporter activity
PSEFU_RS10265	COG1132	(ABC) transporter
PSEFU_RS10270	COG0302	gtp cyclohydrolase
PSEFU_RS10305	COG1653	transport
PSEFU_RS10310	COG1175	transmembrane transport
PSEFU_RS10320	COG3842	ATPase activity
PSEFU_RS10325	COG4580	involved in the transport of maltose and maltodextrins
PSEFU_RS10330	COG1737	Transcriptional regulator
PSEFU_RS10345	COG0800	Aldolase
PSEFU_RS10350	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSEFU_RS10365	COG1793	dna ligase
PSEFU_RS10370	COG1201	RNA secondary structure unwinding
PSEFU_RS10380	COG0840	transmembrane signaling receptor activity
PSEFU_RS10390	COG1073	alpha beta
PSEFU_RS10395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PSEFU_RS10405	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PSEFU_RS10410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSEFU_RS10420	COG1368	sulfuric ester hydrolase activity
PSEFU_RS10450	COG2308	Evidence 4 Homologs of previously reported genes of
PSEFU_RS10460	COG1305	Transglutaminase-like
PSEFU_RS10475	COG0519	Catalyzes the synthesis of GMP from XMP
PSEFU_RS10495	COG0583	DNA-binding transcription factor activity
PSEFU_RS10510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PSEFU_RS10510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PSEFU_RS10535	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS10545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSEFU_RS10595	COG3846	protein secretion by the type IV secretion system
PSEFU_RS10610	COG3451	type IV secretory pathway VirB4
PSEFU_RS10625	COG4962	Type ii secretion system protein e
PSEFU_RS10640	COG0583	DNA-binding transcription factor activity
PSEFU_RS10645	COG2814	Major facilitator Superfamily
PSEFU_RS10650	COG0367	asparagine synthase
PSEFU_RS10665	COG0156	8-amino-7-oxononanoate synthase activity
PSEFU_RS10685	COG1192	Involved in chromosome partitioning
PSEFU_RS10710	COG3135	benzoate transporter
PSEFU_RS10720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSEFU_RS10740	COG2003	Belongs to the UPF0758 family
PSEFU_RS10760	COG1595	DNA-templated transcription, initiation
PSEFU_RS10765	COG3712	iron ion homeostasis
PSEFU_RS10775	COG0583	DNA-binding transcription factor activity
PSEFU_RS10780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSEFU_RS10785	COG4774	siderophore transport
PSEFU_RS10860	COG2356	endonuclease I
PSEFU_RS10890	COG3459	Glycosyltransferase 36 associated
PSEFU_RS10900	COG2204	response regulator
PSEFU_RS10915	COG2188	Transcriptional regulator
PSEFU_RS10920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PSEFU_RS10920	COG1263	PTS System
PSEFU_RS10925	COG0366	Alpha amylase catalytic
PSEFU_RS10930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PSEFU_RS10930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSEFU_RS10950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSEFU_RS10960	COG2271	Major facilitator Superfamily
PSEFU_RS10970	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS10975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSEFU_RS10980	COG1971	Probably functions as a manganese efflux pump
PSEFU_RS10985	COG4993	Dehydrogenase
PSEFU_RS10995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSEFU_RS11000	COG1120	ATPase activity
PSEFU_RS11025	COG0668	transmembrane transport
PSEFU_RS11035	COG2130	NADP-dependent
PSEFU_RS11045	COG3135	benzoate transporter
PSEFU_RS11050	COG1280	lysine exporter protein (LysE YggA)
PSEFU_RS11060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSEFU_RS11065	COG0625	glutathione transferase activity
PSEFU_RS11075	COG0789	Transcriptional regulator
PSEFU_RS11095	COG3530	Putative quorum-sensing-regulated virulence factor
PSEFU_RS11110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSEFU_RS11115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PSEFU_RS11120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSEFU_RS11125	COG0215	cysteine-tRNA ligase activity
PSEFU_RS11130	COG0210	DNA helicase
PSEFU_RS11135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSEFU_RS11155	COG0544	peptidyl-prolyl cis-trans isomerase activity
PSEFU_RS11165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PSEFU_RS11170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PSEFU_RS11180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSEFU_RS11185	COG4172	Belongs to the ABC transporter superfamily
PSEFU_RS11190	COG4239	(ABC) transporter, permease
PSEFU_RS11195	COG4174	ABC transporter (Permease)
PSEFU_RS11205	COG4166	transmembrane transport
PSEFU_RS11210	COG0741	lytic transglycosylase activity
PSEFU_RS11210	COG1388	LysM domain
PSEFU_RS11215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSEFU_RS11225	COG0328	RNA-DNA hybrid ribonuclease activity
PSEFU_RS11240	COG1024	Enoyl-CoA hydratase
PSEFU_RS11250	COG2816	NAD+ diphosphatase activity
PSEFU_RS11255	COG0730	response to heat
PSEFU_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS11285	COG0616	signal peptide processing
PSEFU_RS11290	COG0604	alcohol dehydrogenase
PSEFU_RS11300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSEFU_RS11345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSEFU_RS11350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PSEFU_RS11350	COG0316	Belongs to the HesB IscA family
PSEFU_RS11355	COG2197	response regulator
PSEFU_RS11365	COG0477	Major facilitator Superfamily
PSEFU_RS11370	COG3813	Protein conserved in bacteria
PSEFU_RS11415	COG0431	NADPH-dependent FMN reductase
PSEFU_RS11420	COG2056	Na+-H+ antiporter family
PSEFU_RS11430	COG0628	permease
PSEFU_RS11435	COG1007	ATP synthesis coupled electron transport
PSEFU_RS11450	COG0713	ATP synthesis coupled electron transport
PSEFU_RS11460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSEFU_RS11465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PSEFU_RS11485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSEFU_RS11485	COG0649	NAD binding
PSEFU_RS11490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSEFU_RS11495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSEFU_RS11515	COG2153	protein acetylation
PSEFU_RS11520	COG2850	peptidyl-arginine hydroxylation
PSEFU_RS11530	COG2915	High frequency lysogenization protein hflD homolog
PSEFU_RS11535	COG0482	sulfurtransferase activity
PSEFU_RS11550	COG1278	Cold shock
PSEFU_RS11555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PSEFU_RS11560	COG0542	response to heat
PSEFU_RS11565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PSEFU_RS11575	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PSEFU_RS11580	COG0492	ferredoxin-NADP+ reductase activity
PSEFU_RS11585	COG1674	ftsk spoiiie
PSEFU_RS11590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PSEFU_RS11595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PSEFU_RS11600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PSEFU_RS11610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSEFU_RS11610	COG1648	precorrin-2 dehydrogenase activity
PSEFU_RS11640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSEFU_RS11680	COG1070	Carbohydrate kinase
PSEFU_RS11690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSEFU_RS11700	COG0300	oxidoreductase activity
PSEFU_RS11710	COG2072	flavoprotein involved in K transport
PSEFU_RS11715	COG0300	oxidoreductase activity
PSEFU_RS11725	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS11725	COG0604	alcohol dehydrogenase
PSEFU_RS11725	COG3321	synthase
PSEFU_RS11730	COG1609	Transcriptional regulator
PSEFU_RS11735	COG3265	gluconokinase activity
PSEFU_RS11750	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSEFU_RS11755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSEFU_RS11765	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSEFU_RS11765	COG1024	Enoyl-CoA hydratase
PSEFU_RS11775	COG0633	Ferredoxin
PSEFU_RS11775	COG0543	2 iron, 2 sulfur cluster binding
PSEFU_RS11790	COG0860	N-Acetylmuramoyl-L-alanine amidase
PSEFU_RS11805	COG1120	ATPase activity
PSEFU_RS11810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSEFU_RS11815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSEFU_RS11820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PSEFU_RS11825	COG4264	IucA IucC family
PSEFU_RS11835	COG4264	IucA IucC family
PSEFU_RS11840	COG2814	Major facilitator Superfamily
PSEFU_RS11845	COG0019	diaminopimelate decarboxylase activity
PSEFU_RS11850	COG4264	IucA IucC family
PSEFU_RS11855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSEFU_RS11860	COG4774	siderophore transport
PSEFU_RS11870	COG1595	DNA-templated transcription, initiation
PSEFU_RS11885	COG1304	FMN binding
PSEFU_RS11920	COG1546	Belongs to the CinA family
PSEFU_RS11920	COG1058	Belongs to the CinA family
PSEFU_RS11935	COG4208	sulfate ABC transporter
PSEFU_RS11940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PSEFU_RS11950	COG2116	formate transmembrane transporter activity
PSEFU_RS11960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSEFU_RS11965	COG1116	anion transmembrane transporter activity
PSEFU_RS11975	COG2175	clavaminate synthase activity
PSEFU_RS11990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSEFU_RS11995	COG0765	amino acid transport
PSEFU_RS12000	COG1126	abc transporter atp-binding protein
PSEFU_RS12090	COG0322	excinuclease ABC activity
PSEFU_RS12095	COG2197	response regulator
PSEFU_RS12125	COG3852	Histidine kinase
PSEFU_RS12140	COG3123	guanosine phosphorylase activity
PSEFU_RS12165	COG0436	Aminotransferase
PSEFU_RS12175	COG2610	gluconate transmembrane transporter activity
PSEFU_RS12180	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS12185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSEFU_RS12210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSEFU_RS12215	COG0009	L-threonylcarbamoyladenylate synthase
PSEFU_RS12220	COG3002	Belongs to the UPF0753 family
PSEFU_RS12225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PSEFU_RS12230	COG0583	DNA-binding transcription factor activity
PSEFU_RS12235	COG2897	thiosulfate sulfurtransferase activity
PSEFU_RS12245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSEFU_RS12250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSEFU_RS12260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSEFU_RS12290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PSEFU_RS12295	COG2011	ABC-type metal ion transport system permease component
PSEFU_RS12305	COG2207	Transcriptional regulator
PSEFU_RS12315	COG3706	GGDEF domain
PSEFU_RS12340	COG0488	(ABC) transporter
PSEFU_RS12380	COG0045	succinate-CoA ligase (ADP-forming) activity
PSEFU_RS12400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PSEFU_RS12405	COG1053	succinate dehydrogenase
PSEFU_RS12410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PSEFU_RS12415	COG2009	succinate dehydrogenase
PSEFU_RS12440	COG2920	part of a sulfur-relay system
PSEFU_RS12445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSEFU_RS12450	COG0435	Glutathione S-transferase
PSEFU_RS12455	COG1538	Outer membrane efflux protein
PSEFU_RS12475	COG3386	PFAM SMP-30 Gluconolaconase
PSEFU_RS12480	COG3734	2-keto-3-deoxy-galactonokinase
PSEFU_RS12485	COG0129	dihydroxy-acid dehydratase activity
PSEFU_RS12495	COG4214	carbohydrate transport
PSEFU_RS12505	COG4213	ABC transporter substrate-binding protein
PSEFU_RS12520	COG2911	Protein conserved in bacteria
PSEFU_RS12525	COG0729	surface antigen
PSEFU_RS12540	COG0861	Integral membrane protein TerC family
PSEFU_RS12580	COG0668	transmembrane transport
PSEFU_RS12595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PSEFU_RS12610	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PSEFU_RS12615	COG1280	lysine exporter protein (LysE YggA)
PSEFU_RS12620	COG2828	Protein conserved in bacteria
PSEFU_RS12640	COG1802	Transcriptional regulator
PSEFU_RS12655	COG0189	ligase activity
PSEFU_RS12660	COG0175	sulfate reduction
PSEFU_RS12670	COG0589	response to stress
PSEFU_RS12685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSEFU_RS12700	COG1376	ErfK ybiS ycfS ynhG family protein
PSEFU_RS12715	COG4181	ATPase activity
PSEFU_RS12720	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PSEFU_RS12735	COG2259	Doxx family
PSEFU_RS12740	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PSEFU_RS12745	COG0084	hydrolase, TatD family'
PSEFU_RS12780	COG0714	Associated with various cellular activities
PSEFU_RS12795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSEFU_RS12810	COG0628	permease
PSEFU_RS12835	COG2062	phosphohistidine phosphatase, SixA
PSEFU_RS12845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PSEFU_RS12860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSEFU_RS12920	COG1278	Cold shock
PSEFU_RS12925	COG1968	undecaprenyl-diphosphatase activity
PSEFU_RS12935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PSEFU_RS12940	COG2010	Cytochrome c
PSEFU_RS12945	COG0753	catalase activity
PSEFU_RS12950	COG0720	synthase
PSEFU_RS12980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PSEFU_RS12985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSEFU_RS12990	COG1309	transcriptional regulator
PSEFU_RS12995	COG1082	Xylose isomerase domain protein TIM barrel
PSEFU_RS12995	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PSEFU_RS13000	COG0477	Major facilitator Superfamily
PSEFU_RS13040	COG3181	Tripartite tricarboxylate transporter family receptor
PSEFU_RS13065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PSEFU_RS13070	COG3115	cell septum assembly
PSEFU_RS13085	COG0402	S-adenosylhomocysteine deaminase activity
PSEFU_RS13090	COG1120	ATPase activity
PSEFU_RS13095	COG4139	cobalamin transport
PSEFU_RS13110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PSEFU_RS13125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PSEFU_RS13125	COG2010	Cytochrome c
PSEFU_RS13130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PSEFU_RS13155	COG4215	(ABC) transporter
PSEFU_RS13160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSEFU_RS13165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSEFU_RS13170	COG2200	EAL domain
PSEFU_RS13190	COG0583	DNA-binding transcription factor activity
PSEFU_RS13195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSEFU_RS13200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSEFU_RS13205	COG2814	Major facilitator Superfamily
PSEFU_RS13210	COG1566	PFAM secretion protein HlyD family protein
PSEFU_RS13220	COG1846	Transcriptional regulator
PSEFU_RS13245	COG2079	MmgE PrpD family protein
PSEFU_RS13250	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS13255	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PSEFU_RS13260	COG0583	DNA-binding transcription factor activity
PSEFU_RS13330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PSEFU_RS13355	COG1024	Enoyl-CoA hydratase
PSEFU_RS13360	COG0598	Magnesium transport protein CorA
PSEFU_RS13365	COG0842	Transport permease protein
PSEFU_RS13370	COG1131	(ABC) transporter
PSEFU_RS13375	COG0625	glutathione transferase activity
PSEFU_RS13415	COG1956	GAF domain-containing protein
PSEFU_RS13420	COG2255	four-way junction helicase activity
PSEFU_RS13425	COG0784	Response regulator, receiver
PSEFU_RS13425	COG2205	protein histidine kinase activity
PSEFU_RS13425	COG5002	protein histidine kinase activity
PSEFU_RS13430	COG1846	Transcriptional regulator
PSEFU_RS13435	COG0386	Belongs to the glutathione peroxidase family
PSEFU_RS13440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSEFU_RS13445	COG0436	Aminotransferase
PSEFU_RS13455	COG0501	Belongs to the peptidase M48B family
PSEFU_RS13460	COG0500	methyltransferase
PSEFU_RS13465	COG3384	dioxygenase
PSEFU_RS13490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PSEFU_RS13510	COG1595	DNA-templated transcription, initiation
PSEFU_RS13515	COG2304	oxidoreductase activity
PSEFU_RS13520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSEFU_RS13570	COG1309	transcriptional regulator
PSEFU_RS13580	COG0084	hydrolase, TatD family'
PSEFU_RS13595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PSEFU_RS13600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PSEFU_RS13610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSEFU_RS13615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PSEFU_RS13630	COG0416	fatty acid biosynthetic process
PSEFU_RS13635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PSEFU_RS13640	COG1399	metal-binding, possibly nucleic acid-binding protein
PSEFU_RS13645	COG0424	maF-like protein
PSEFU_RS13650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PSEFU_RS13655	COG1074	ATP-dependent DNA helicase activity
PSEFU_RS13660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PSEFU_RS13680	COG0840	transmembrane signaling receptor activity
PSEFU_RS13685	COG2323	membrane
PSEFU_RS13725	COG0776	regulation of translation
PSEFU_RS13730	COG0072	phenylalanine-tRNA ligase activity
PSEFU_RS13735	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PSEFU_RS13740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PSEFU_RS13745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PSEFU_RS13750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PSEFU_RS13755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PSEFU_RS13775	COG0583	DNA-binding transcription factor activity
PSEFU_RS13780	COG0656	L-ascorbic acid biosynthetic process
PSEFU_RS13795	COG0840	transmembrane signaling receptor activity
PSEFU_RS13800	COG1113	amino acid transport
PSEFU_RS13805	COG0625	glutathione transferase activity
PSEFU_RS13815	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PSEFU_RS13840	COG1054	Belongs to the UPF0176 family
PSEFU_RS13845	COG0604	alcohol dehydrogenase
PSEFU_RS13850	COG0271	Belongs to the BolA IbaG family
PSEFU_RS13865	COG0114	fumarate hydratase activity
PSEFU_RS13870	COG2249	NAD(P)H dehydrogenase (quinone) activity
PSEFU_RS13880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PSEFU_RS13885	COG3485	protocatechuate 3,4-dioxygenase
PSEFU_RS13890	COG3485	protocatechuate 3,4-dioxygenase
PSEFU_RS13900	COG1733	regulation of RNA biosynthetic process
PSEFU_RS13910	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS13920	COG0583	DNA-binding transcription factor activity
PSEFU_RS13925	COG0297	glycogen (starch) synthase activity
PSEFU_RS13930	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PSEFU_RS13935	COG1640	4-alpha-glucanotransferase
PSEFU_RS13975	COG0517	IMP dehydrogenase activity
PSEFU_RS13985	COG3568	Endonuclease Exonuclease Phosphatase
PSEFU_RS13990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PSEFU_RS13995	COG0392	lysyltransferase activity
PSEFU_RS14010	COG2808	Putative FMN-binding domain
PSEFU_RS14065	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PSEFU_RS14075	COG1285	pathogenesis
PSEFU_RS14100	COG0058	SHG alpha-glucan phosphorylase activity
PSEFU_RS14125	COG1846	Transcriptional regulator
PSEFU_RS14130	COG1764	response to oxidative stress
PSEFU_RS14140	COG4221	oxidoreductase activity
PSEFU_RS14145	COG2207	Transcriptional regulator
PSEFU_RS14155	COG3712	iron ion homeostasis
PSEFU_RS14160	COG1595	DNA-templated transcription, initiation
PSEFU_RS14165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PSEFU_RS14170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PSEFU_RS14175	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PSEFU_RS14190	COG3738	Protein conserved in bacteria
PSEFU_RS14195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSEFU_RS14210	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PSEFU_RS14220	COG0840	transmembrane signaling receptor activity
PSEFU_RS14265	COG3278	Belongs to the heme-copper respiratory oxidase family
PSEFU_RS14280	COG2010	Cytochrome c
PSEFU_RS14285	COG3278	Belongs to the heme-copper respiratory oxidase family
PSEFU_RS14300	COG2010	Cytochrome c
PSEFU_RS14315	COG2217	Heavy metal translocating P-type atpase
PSEFU_RS14340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PSEFU_RS14350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSEFU_RS14350	COG0616	signal peptide processing
PSEFU_RS14355	COG0546	phosphoglycolate phosphatase activity
PSEFU_RS14365	COG1530	ribonuclease E activity
PSEFU_RS14370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PSEFU_RS14375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSEFU_RS14380	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PSEFU_RS14385	COG2835	tetraacyldisaccharide 4'-kinase activity
PSEFU_RS14390	COG1663	tetraacyldisaccharide 4'-kinase activity
PSEFU_RS14395	COG0848	biopolymer transport protein
PSEFU_RS14405	COG0658	competence protein
PSEFU_RS14405	COG2333	competence protein COMEC
PSEFU_RS14415	COG1136	(ABC) transporter
PSEFU_RS14435	COG0584	glycerophosphoryl diester phosphodiesterase
PSEFU_RS14445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSEFU_RS14455	COG1477	protein flavinylation
PSEFU_RS14465	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PSEFU_RS14480	COG1805	sodium ion transport
PSEFU_RS14495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PSEFU_RS14510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSEFU_RS14540	COG0183	Belongs to the thiolase family
PSEFU_RS14545	COG1024	Enoyl-CoA hydratase
PSEFU_RS14545	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSEFU_RS14560	COG0589	response to stress
PSEFU_RS14565	COG0488	(ABC) transporter
PSEFU_RS14590	COG0303	'Molybdopterin
PSEFU_RS14595	COG0521	Mo-molybdopterin cofactor biosynthetic process
PSEFU_RS14600	COG0746	molybdenum cofactor guanylyltransferase activity
PSEFU_RS14620	COG1301	dicarboxylic acid transport
PSEFU_RS14640	COG4459	periplasmic nitrate reductase
PSEFU_RS14645	COG3062	negative regulation of establishment of protein localization
PSEFU_RS14650	COG0243	molybdopterin cofactor binding
PSEFU_RS14655	COG3043	anaerobic respiration
PSEFU_RS14660	COG3005	denitrification pathway
PSEFU_RS14670	COG1362	aminopeptidase activity
PSEFU_RS14675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSEFU_RS14680	COG0668	transmembrane transport
PSEFU_RS14685	COG1704	LemA family
PSEFU_RS14690	COG0501	Belongs to the peptidase M48B family
PSEFU_RS14705	COG3781	membrane
PSEFU_RS14735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSEFU_RS14750	COG0483	inositol monophosphate 1-phosphatase activity
PSEFU_RS14775	COG1280	lysine exporter protein (LysE YggA)
PSEFU_RS14795	COG0217	transcriptional regulatory protein
PSEFU_RS14825	COG3706	GGDEF domain
PSEFU_RS14830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSEFU_RS14835	COG3162	membrane
PSEFU_RS14845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSEFU_RS14855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PSEFU_RS14865	COG4774	siderophore transport
PSEFU_RS14865	COG1629	transport
PSEFU_RS14880	COG0625	glutathione transferase activity
PSEFU_RS14890	COG2996	Protein conserved in bacteria
PSEFU_RS14900	COG1368	sulfuric ester hydrolase activity
PSEFU_RS14925	COG0513	Belongs to the DEAD box helicase family
PSEFU_RS14955	COG1132	(ABC) transporter
PSEFU_RS14985	COG1733	regulation of RNA biosynthetic process
PSEFU_RS14990	COG0604	alcohol dehydrogenase
PSEFU_RS14990	COG4221	oxidoreductase activity
PSEFU_RS14990	COG3321	synthase
PSEFU_RS14990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PSEFU_RS15000	COG3300	MHYT domain
PSEFU_RS15000	COG5001	Diguanylate cyclase
PSEFU_RS15020	COG4786	Flagellar basal body rod
PSEFU_RS15020	COG1256	bacterial-type flagellum assembly
PSEFU_RS15025	COG0741	lytic transglycosylase activity
PSEFU_RS15030	COG1706	bacterial-type flagellum-dependent cell motility
PSEFU_RS15040	COG4786	Flagellar basal body rod
PSEFU_RS15055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PSEFU_RS15060	COG1558	bacterial-type flagellum-dependent cell motility
PSEFU_RS15075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PSEFU_RS15095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PSEFU_RS15100	COG1191	sigma factor activity
PSEFU_RS15125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PSEFU_RS15155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PSEFU_RS15165	COG1677	Flagellar hook-basal body complex protein FliE
PSEFU_RS15190	COG1987	bacterial-type flagellum assembly
PSEFU_RS15195	COG1684	flagellar biosynthetic protein fliR
PSEFU_RS15230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSEFU_RS15240	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PSEFU_RS15260	COG2271	Major facilitator Superfamily
PSEFU_RS15295	COG1286	toxin biosynthetic process
PSEFU_RS15300	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PSEFU_RS15305	COG0285	dihydrofolate synthase activity
PSEFU_RS15310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PSEFU_RS15315	COG0135	phosphoribosylanthranilate isomerase activity
PSEFU_RS15340	COG0473	3-isopropylmalate dehydrogenase activity
PSEFU_RS15345	COG0066	3-isopropylmalate dehydratase activity
PSEFU_RS15350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PSEFU_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS15410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSEFU_RS15420	COG0556	nucleotide-excision repair
PSEFU_RS15460	COG1516	flagellar protein fliS
PSEFU_RS15465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PSEFU_RS15475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PSEFU_RS15495	COG1706	bacterial-type flagellum-dependent cell motility
PSEFU_RS15500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PSEFU_RS15510	COG4787	bacterial-type flagellum-dependent cell motility
PSEFU_RS15515	COG1749	Flagellar hook protein flgE
PSEFU_RS15525	COG1558	bacterial-type flagellum-dependent cell motility
PSEFU_RS15530	COG1815	bacterial-type flagellum-dependent cell motility
PSEFU_RS15535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PSEFU_RS15540	COG0784	Response regulator, receiver
PSEFU_RS15540	COG0835	chemotaxis
PSEFU_RS15560	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PSEFU_RS15585	COG1522	sequence-specific DNA binding
PSEFU_RS15610	COG2239	Acts as a magnesium transporter
PSEFU_RS15640	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PSEFU_RS15645	COG0527	aspartate kinase activity
PSEFU_RS15650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PSEFU_RS15655	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PSEFU_RS15660	COG2988	succinylglutamate desuccinylase activity
PSEFU_RS15670	COG3724	N-succinylarginine dihydrolase activity
PSEFU_RS15690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PSEFU_RS15710	COG3387	PFAM Glycoside hydrolase 15-related
PSEFU_RS15715	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS15720	COG1546	Belongs to the CinA family
PSEFU_RS15720	COG1058	Belongs to the CinA family
PSEFU_RS15725	COG0028	Belongs to the TPP enzyme family
PSEFU_RS15760	COG2974	May be involved in recombination
PSEFU_RS15765	COG0385	Bile acid
PSEFU_RS15770	COG2076	Multidrug Resistance protein
PSEFU_RS15785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSEFU_RS15785	COG1017	nitric oxide dioxygenase activity
PSEFU_RS15790	COG0625	glutathione transferase activity
PSEFU_RS15800	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PSEFU_RS15815	COG2205	protein histidine kinase activity
PSEFU_RS15865	COG1595	DNA-templated transcription, initiation
PSEFU_RS15875	COG4774	siderophore transport
PSEFU_RS15880	COG0840	transmembrane signaling receptor activity
PSEFU_RS15905	COG0625	glutathione transferase activity
PSEFU_RS15910	COG3609	addiction module antidote protein, CC2985 family
PSEFU_RS15980	COG0587	DNA-directed DNA polymerase activity
PSEFU_RS15985	COG2153	protein acetylation
PSEFU_RS16015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PSEFU_RS16020	COG2271	Major facilitator Superfamily
PSEFU_RS16040	COG3622	Belongs to the hyi family
PSEFU_RS16085	COG4807	Protein conserved in bacteria
PSEFU_RS16095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PSEFU_RS16100	COG0243	molybdopterin cofactor binding
PSEFU_RS16105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PSEFU_RS16110	COG3842	ATPase activity
PSEFU_RS16125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PSEFU_RS16135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSEFU_RS16150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSEFU_RS16155	COG0583	DNA-binding transcription factor activity
PSEFU_RS16170	COG2226	methyltransferase
PSEFU_RS16175	COG0500	methyltransferase
PSEFU_RS16185	COG1381	Involved in DNA repair and RecF pathway recombination
PSEFU_RS16190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PSEFU_RS16195	COG0571	ribonuclease III activity
PSEFU_RS16210	COG0481	GTPase activity
PSEFU_RS16215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSEFU_RS16250	COG0354	folic acid binding
PSEFU_RS16290	COG3180	Ammonia monooxygenase
PSEFU_RS16300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PSEFU_RS16310	COG1024	Enoyl-CoA hydratase
PSEFU_RS16315	COG1024	Enoyl-CoA hydratase
PSEFU_RS16320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSEFU_RS16325	COG2274	protein secretion by the type I secretion system
PSEFU_RS16345	COG3300	MHYT domain
PSEFU_RS16345	COG5001	Diguanylate cyclase
PSEFU_RS16370	COG3842	ATPase activity
PSEFU_RS16375	COG3665	Urea carboxylase-associated protein
PSEFU_RS16380	COG3665	Urea carboxylase-associated protein
PSEFU_RS16385	COG0439	Biotin carboxylase
PSEFU_RS16420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PSEFU_RS16425	COG4139	cobalamin transport
PSEFU_RS16430	COG1120	ATPase activity
PSEFU_RS16460	COG1160	GTP binding
PSEFU_RS16475	COG0124	histidyl-tRNA synthetase
PSEFU_RS16480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PSEFU_RS16485	COG1426	Protein conserved in bacteria
PSEFU_RS16495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PSEFU_RS16500	COG0105	UTP biosynthetic process
PSEFU_RS16510	COG0633	Ferredoxin
PSEFU_RS16515	COG0443	Heat shock 70 kDa protein
PSEFU_RS16520	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PSEFU_RS16525	COG0316	Belongs to the HesB IscA family
PSEFU_RS16535	COG1104	cysteine desulfurase activity
PSEFU_RS16545	COG1045	serine acetyltransferase
PSEFU_RS16560	COG3134	Outer membrane lipoprotein
PSEFU_RS16575	COG1862	Preprotein translocase
PSEFU_RS16580	COG0343	queuine tRNA-ribosyltransferase activity
PSEFU_RS16585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PSEFU_RS16595	COG1278	Cold shock
PSEFU_RS16605	COG0795	lipopolysaccharide-transporting ATPase activity
PSEFU_RS16610	COG0795	lipopolysaccharide-transporting ATPase activity
PSEFU_RS16615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PSEFU_RS16640	COG0490	domain, Protein
PSEFU_RS16640	COG0471	metal ion transport
PSEFU_RS16645	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PSEFU_RS16655	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PSEFU_RS16660	COG1320	monovalent cation:proton antiporter activity
PSEFU_RS16665	COG2212	antiporter activity
PSEFU_RS16670	COG1863	multisubunit Na H antiporter MnhE subunit
PSEFU_RS16675	COG0651	ATP synthesis coupled electron transport
PSEFU_RS16680	COG1006	Multisubunit Na H antiporter MnhC subunit
PSEFU_RS16685	COG2111	Na H antiporter
PSEFU_RS16685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PSEFU_RS16695	COG1929	Belongs to the glycerate kinase type-1 family
PSEFU_RS16705	COG3835	regulator
PSEFU_RS16710	COG0259	pyridoxamine-phosphate oxidase activity
PSEFU_RS16730	COG1199	ATP-dependent helicase activity
PSEFU_RS16760	COG3012	SEC-C Motif Domain Protein
PSEFU_RS16790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSEFU_RS16795	COG0243	molybdopterin cofactor binding
PSEFU_RS16800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSEFU_RS16805	COG3707	response regulator
PSEFU_RS16810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSEFU_RS16815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSEFU_RS16820	COG1116	anion transmembrane transporter activity
PSEFU_RS16830	COG0717	Belongs to the dCTP deaminase family
PSEFU_RS16835	COG1278	Cold shock
PSEFU_RS16840	COG0489	protein tyrosine kinase activity
PSEFU_RS16845	COG2885	chlorophyll binding
PSEFU_RS16850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSEFU_RS16850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSEFU_RS16860	COG2878	Part of a membrane complex involved in electron transport
PSEFU_RS16865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PSEFU_RS16875	COG0492	ferredoxin-NADP+ reductase activity
PSEFU_RS16880	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PSEFU_RS16890	COG0386	Belongs to the glutathione peroxidase family
PSEFU_RS16900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PSEFU_RS16910	COG0204	Acyl-transferase
PSEFU_RS16920	COG2885	chlorophyll binding
PSEFU_RS16925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSEFU_RS16940	COG0318	PFAM AMP-dependent synthetase and ligase
PSEFU_RS16945	COG0183	Belongs to the thiolase family
PSEFU_RS16950	COG1280	lysine exporter protein (LysE YggA)
PSEFU_RS16955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSEFU_RS16960	COG2813	Specifically methylates the guanine in position
PSEFU_RS16965	COG2119	membrane
PSEFU_RS16970	COG0501	Belongs to the peptidase M48B family
PSEFU_RS17020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PSEFU_RS17025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PSEFU_RS17030	COG0585	pseudouridine synthase activity
PSEFU_RS17035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PSEFU_RS17040	COG0783	Belongs to the Dps family
PSEFU_RS17055	COG0583	DNA-binding transcription factor activity
PSEFU_RS17065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PSEFU_RS17075	COG0148	phosphopyruvate hydratase activity
PSEFU_RS17080	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PSEFU_RS17085	COG0504	CTP synthase activity
PSEFU_RS17095	COG0825	malonyl-CoA metabolic process
PSEFU_RS17105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PSEFU_RS17110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSEFU_RS17115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PSEFU_RS17120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSEFU_RS17145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PSEFU_RS17155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PSEFU_RS17160	COG0233	cytoplasmic translational termination
PSEFU_RS17165	COG0528	UMP kinase activity
PSEFU_RS17170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PSEFU_RS17175	COG0052	Belongs to the universal ribosomal protein uS2 family
PSEFU_RS17180	COG0024	Methionine aminopeptidase
PSEFU_RS17185	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PSEFU_RS17195	COG0436	Aminotransferase
PSEFU_RS17210	COG3546	catalase activity
PSEFU_RS17215	COG3685	Protein conserved in bacteria
PSEFU_RS17240	COG2205	protein histidine kinase activity
PSEFU_RS17240	COG4999	Histidine kinase
PSEFU_RS17240	COG3437	response regulator, receiver
PSEFU_RS17240	COG3850	Histidine kinase
PSEFU_RS17250	COG0351	phosphomethylpyrimidine kinase
PSEFU_RS17250	COG0352	thiamine-phosphate diphosphorylase activity
PSEFU_RS17260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSEFU_RS17275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSEFU_RS17280	COG1702	phosphate starvation-inducible protein PhoH
PSEFU_RS17285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PSEFU_RS17290	COG4535	Mg2 and Co2 transporter CorC
PSEFU_RS17295	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PSEFU_RS17300	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PSEFU_RS17310	COG0495	leucyl-tRNA aminoacylation
PSEFU_RS17330	COG2951	lytic endotransglycosylase activity
PSEFU_RS17335	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS17340	COG0025	NhaP-type Na H and K H
PSEFU_RS17345	COG1393	Belongs to the ArsC family
PSEFU_RS17350	COG2171	N-acyltransferase activity
PSEFU_RS17355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSEFU_RS17360	COG2166	iron-sulfur cluster assembly
PSEFU_RS17365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PSEFU_RS17370	COG1215	transferase activity, transferring glycosyl groups
PSEFU_RS17375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSEFU_RS17380	COG2226	methyltransferase
PSEFU_RS17450	COG1408	metallophosphoesterase
PSEFU_RS17455	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PSEFU_RS17460	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PSEFU_RS17460	COG3608	succinylglutamate desuccinylase aspartoacylase
PSEFU_RS17495	COG2851	Citrate transporter
PSEFU_RS17500	COG0861	Integral membrane protein TerC family
PSEFU_RS17515	COG0612	Peptidase, M16
PSEFU_RS17520	COG4948	Mandelate Racemase Muconate Lactonizing
PSEFU_RS17525	COG3618	amidohydrolase
PSEFU_RS17530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PSEFU_RS17540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PSEFU_RS17545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PSEFU_RS17550	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PSEFU_RS17565	COG2271	Major facilitator Superfamily
PSEFU_RS17585	COG0583	DNA-binding transcription factor activity
PSEFU_RS17590	COG2937	Belongs to the GPAT DAPAT family
PSEFU_RS17625	COG1228	amidohydrolase
PSEFU_RS17630	COG0010	Belongs to the arginase family
PSEFU_RS17635	COG3314	Sporulation integral membrane protein YlbJ
PSEFU_RS17650	COG2188	Transcriptional regulator
PSEFU_RS17665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSEFU_RS17670	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PSEFU_RS17675	COG2080	2 iron, 2 sulfur cluster binding
PSEFU_RS17680	COG0742	ribosomal rna small subunit methyltransferase
PSEFU_RS17710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSEFU_RS17715	COG3030	protein affecting phage T7 exclusion by the F plasmid
PSEFU_RS17720	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS17730	COG3695	enzyme binding
PSEFU_RS17740	COG0668	transmembrane transport
PSEFU_RS17745	COG1666	GTP binding
PSEFU_RS17750	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS17760	COG4191	Histidine kinase
PSEFU_RS17760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSEFU_RS17765	COG2096	Adenosyltransferase
PSEFU_RS17770	COG0564	pseudouridine synthase activity
PSEFU_RS17780	COG0494	nUDIX hydrolase
PSEFU_RS17795	COG0653	protein targeting
PSEFU_RS17800	COG0739	heme binding
PSEFU_RS17800	COG0741	lytic transglycosylase activity
PSEFU_RS17800	COG1196	nuclear chromosome segregation
PSEFU_RS17810	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PSEFU_RS17830	COG1181	Belongs to the D-alanine--D-alanine ligase family
PSEFU_RS17835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PSEFU_RS17840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PSEFU_RS17845	COG0772	Belongs to the SEDS family
PSEFU_RS17850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PSEFU_RS17855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSEFU_RS17860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PSEFU_RS17865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PSEFU_RS17880	COG0275	rRNA processing
PSEFU_RS17885	COG2001	Belongs to the MraZ family
PSEFU_RS17895	COG3107	peptidoglycan biosynthetic process
PSEFU_RS17900	COG0792	nuclease activity
PSEFU_RS17910	COG2823	Periplasmic or secreted lipoprotein
PSEFU_RS17915	COG1185	polyribonucleotide nucleotidyltransferase activity
PSEFU_RS17920	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PSEFU_RS17925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PSEFU_RS17930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PSEFU_RS17935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PSEFU_RS17940	COG2251	uridine kinase activity
PSEFU_RS17940	COG0195	Participates in both transcription termination and antitermination
PSEFU_RS17945	COG0779	Required for maturation of 30S ribosomal subunits
PSEFU_RS17960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PSEFU_RS17965	COG0149	triose-phosphate isomerase activity
PSEFU_RS17970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSEFU_RS17975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PSEFU_RS18000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSEFU_RS18015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PSEFU_RS18020	COG0484	heat shock protein binding
PSEFU_RS18025	COG0443	Heat shock 70 kDa protein
PSEFU_RS18030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSEFU_RS18035	COG0497	DNA recombination
PSEFU_RS18045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSEFU_RS18050	COG2914	Belongs to the UPF0125 (RnfH) family
PSEFU_RS18060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PSEFU_RS18070	COG1620	l-lactate permease
PSEFU_RS18080	COG0277	FAD linked oxidase domain protein
PSEFU_RS18085	COG1522	sequence-specific DNA binding
PSEFU_RS18110	COG0251	oxidation-reduction process
PSEFU_RS18115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PSEFU_RS18120	COG0321	lipoyl(octanoyl) transferase activity
PSEFU_RS18125	COG2921	Belongs to the UPF0250 family
PSEFU_RS18130	COG1686	Belongs to the peptidase S11 family
PSEFU_RS18140	COG2951	lytic endotransglycosylase activity
PSEFU_RS18145	COG0772	Belongs to the SEDS family
PSEFU_RS18150	COG0768	penicillin binding
PSEFU_RS18165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PSEFU_RS18175	COG0586	Pfam SNARE associated Golgi protein
PSEFU_RS18185	COG1346	cytolysis
PSEFU_RS18200	COG0702	epimerase
PSEFU_RS18205	COG2851	Citrate transporter
PSEFU_RS18210	COG0300	oxidoreductase activity
PSEFU_RS18215	COG0387	Pfam Sodium calcium exchanger
PSEFU_RS18220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PSEFU_RS18240	COG0583	DNA-binding transcription factor activity
PSEFU_RS18245	COG0604	alcohol dehydrogenase
PSEFU_RS18255	COG1489	DNA binding
PSEFU_RS18260	COG0436	Aminotransferase
PSEFU_RS18265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PSEFU_RS18270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSEFU_RS18280	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PSEFU_RS18295	COG0175	sulfate reduction
PSEFU_RS18305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSEFU_RS18325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PSEFU_RS18330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PSEFU_RS18335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PSEFU_RS18360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSEFU_RS18365	COG1127	ABC transporter
PSEFU_RS18375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PSEFU_RS18385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PSEFU_RS18390	COG1137	ATPase activity
PSEFU_RS18395	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PSEFU_RS18410	COG1660	Displays ATPase and GTPase activities
PSEFU_RS18440	COG0312	modulator of DNA gyrase
PSEFU_RS18445	COG3028	Belongs to the UPF0307 family
PSEFU_RS18450	COG0312	modulator of DNA gyrase
PSEFU_RS18455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSEFU_RS18470	COG0424	maF-like protein
PSEFU_RS18480	COG1792	Involved in formation and maintenance of cell shape
PSEFU_RS18485	COG1077	Cell shape determining protein MreB Mrl
PSEFU_RS18490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PSEFU_RS18495	COG0154	amidase activity
PSEFU_RS18500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PSEFU_RS18505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PSEFU_RS18515	COG0517	IMP dehydrogenase activity
PSEFU_RS18515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSEFU_RS18515	COG0617	tRNA 3'-terminal CCA addition
PSEFU_RS18520	COG4676	Protein conserved in bacteria
PSEFU_RS18525	COG5445	Predicted secreted protein (DUF2300)
PSEFU_RS18540	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PSEFU_RS18545	COG4676	Protein conserved in bacteria
PSEFU_RS18555	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PSEFU_RS18565	COG2271	Major facilitator Superfamily
PSEFU_RS18575	COG0747	negative chemotaxis
PSEFU_RS18580	COG0747	negative chemotaxis
PSEFU_RS18585	COG0006	proline dipeptidase activity
PSEFU_RS18595	COG0747	negative chemotaxis
PSEFU_RS18600	COG0747	negative chemotaxis
PSEFU_RS18605	COG0601	transmembrane transport
PSEFU_RS18610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSEFU_RS18615	COG0444	Belongs to the ABC transporter superfamily
PSEFU_RS18620	COG4608	Belongs to the ABC transporter superfamily
PSEFU_RS18625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PSEFU_RS18635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PSEFU_RS18640	COG4650	regulator
PSEFU_RS18650	COG1690	Belongs to the RtcB family
PSEFU_RS18660	COG3541	Predicted nucleotidyltransferase
PSEFU_RS18665	COG0430	RNA-3'-phosphate cyclase activity
PSEFU_RS18670	COG0488	(ABC) transporter
PSEFU_RS18680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSEFU_RS18695	COG2197	response regulator
PSEFU_RS18705	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PSEFU_RS18710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSEFU_RS18750	COG3842	ATPase activity
PSEFU_RS18770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PSEFU_RS18795	COG3958	Transketolase
PSEFU_RS18800	COG3959	Transketolase, thiamine diphosphate binding domain
PSEFU_RS18805	COG2271	Major facilitator Superfamily
PSEFU_RS18810	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS18815	COG0583	DNA-binding transcription factor activity
PSEFU_RS18820	COG4251	negative regulation of phosphorylation
PSEFU_RS18820	COG3706	GGDEF domain
PSEFU_RS18820	COG2203	Gaf domain
PSEFU_RS18820	COG5001	Diguanylate cyclase
PSEFU_RS18825	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSEFU_RS18830	COG1028	Short-chain dehydrogenase reductase Sdr
PSEFU_RS18835	COG2271	Major facilitator Superfamily
PSEFU_RS18840	COG0583	DNA-binding transcription factor activity
PSEFU_RS18850	COG0129	dihydroxy-acid dehydratase activity
PSEFU_RS18860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PSEFU_RS18865	COG1722	exodeoxyribonuclease VII activity
PSEFU_RS18870	COG0142	geranyltranstransferase activity
PSEFU_RS18875	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PSEFU_RS18880	COG0840	transmembrane signaling receptor activity
PSEFU_RS18895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSEFU_RS18905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PSEFU_RS18910	COG4993	Dehydrogenase
PSEFU_RS18930	COG2813	Specifically methylates the guanine in position
PSEFU_RS18955	COG0463	Glycosyl transferase, family 2
PSEFU_RS18980	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PSEFU_RS18985	COG0237	dephospho-CoA kinase activity
PSEFU_RS19000	COG1252	NADH dehydrogenase
PSEFU_RS19030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PSEFU_RS19050	COG0824	Thioesterase
PSEFU_RS19055	COG1454	alcohol dehydrogenase
PSEFU_RS19070	COG0778	Nitroreductase
PSEFU_RS19075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSEFU_RS19080	COG1127	ABC transporter
PSEFU_RS19130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSEFU_RS19170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PSEFU_RS19175	COG4608	Belongs to the ABC transporter superfamily
PSEFU_RS19180	COG0444	Belongs to the ABC transporter superfamily
PSEFU_RS19185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSEFU_RS19190	COG0747	negative chemotaxis
PSEFU_RS19195	COG0601	transmembrane transport
PSEFU_RS19200	COG0747	negative chemotaxis
PSEFU_RS19205	COG4948	Mandelate Racemase Muconate Lactonizing
PSEFU_RS19215	COG0431	NADPH-dependent FMN reductase
PSEFU_RS19220	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS19230	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS19260	COG0156	8-amino-7-oxononanoate synthase activity
PSEFU_RS19265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PSEFU_RS19270	COG1040	competence protein
PSEFU_RS19275	COG2005	Transcriptional regulator
PSEFU_RS19275	COG3585	molybdate ion transport
PSEFU_RS19295	COG0456	acetyltransferase
PSEFU_RS19325	COG0826	peptidase U32
PSEFU_RS19335	COG4452	Inner membrane protein CreD
PSEFU_RS19340	COG0517	IMP dehydrogenase activity
PSEFU_RS19345	COG2205	protein histidine kinase activity
PSEFU_RS19350	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS19365	COG1126	abc transporter atp-binding protein
PSEFU_RS19370	COG0765	amino acid transport
PSEFU_RS19380	COG1490	D-aminoacyl-tRNA deacylase activity
PSEFU_RS19395	COG3040	lipid binding
PSEFU_RS19435	COG1215	transferase activity, transferring glycosyl groups
PSEFU_RS19455	COG1696	Membrane protein involved in D-alanine export
PSEFU_RS19495	COG1217	gtp-binding protein TYPA
PSEFU_RS19500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSEFU_RS19500	COG0301	tRNA thio-modification
PSEFU_RS19520	COG3852	Histidine kinase
PSEFU_RS19535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PSEFU_RS19540	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PSEFU_RS19550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSEFU_RS19555	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PSEFU_RS19560	COG4942	peptidase
PSEFU_RS19565	COG0793	Belongs to the peptidase S41A family
PSEFU_RS19590	COG1538	Outer membrane efflux protein
PSEFU_RS19615	COG0107	imidazoleglycerol-phosphate synthase activity
PSEFU_RS19620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PSEFU_RS19630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PSEFU_RS19635	COG0131	Imidazoleglycerol-phosphate dehydratase
PSEFU_RS19640	COG2223	nitrite transmembrane transporter activity
PSEFU_RS19650	COG1194	a g-specific adenine glycosylase
PSEFU_RS19655	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PSEFU_RS19675	COG0546	phosphoglycolate phosphatase activity
PSEFU_RS19680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PSEFU_RS19685	COG0659	secondary active sulfate transmembrane transporter activity
PSEFU_RS19690	COG1454	alcohol dehydrogenase
PSEFU_RS19700	COG1177	transmembrane transport
PSEFU_RS19705	COG1176	ABC-type spermidine putrescine transport system, permease component I
PSEFU_RS19715	COG3842	ATPase activity
PSEFU_RS19720	COG2197	response regulator
PSEFU_RS19735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PSEFU_RS19740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PSEFU_RS19745	COG3178	'Phosphotransferase
PSEFU_RS19750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PSEFU_RS19755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSEFU_RS19765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PSEFU_RS19770	COG2967	ApaG domain
PSEFU_RS19775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PSEFU_RS19780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSEFU_RS19785	COG2766	serine protein kinase
PSEFU_RS19790	COG2718	Belongs to the UPF0229 family
PSEFU_RS19795	COG2719	SpoVR family
PSEFU_RS19800	COG0617	tRNA 3'-terminal CCA addition
PSEFU_RS19810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PSEFU_RS19815	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PSEFU_RS19820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PSEFU_RS19825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PSEFU_RS19835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PSEFU_RS19840	COG0523	cobalamin synthesis protein
PSEFU_RS19845	COG2879	small protein
PSEFU_RS19850	COG1966	Carbon starvation protein
PSEFU_RS19905	COG1253	flavin adenine dinucleotide binding
PSEFU_RS19915	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS19935	COG2813	Specifically methylates the guanine in position
PSEFU_RS19960	COG1294	oxidase, subunit
PSEFU_RS19965	COG1271	oxidase subunit
PSEFU_RS19975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PSEFU_RS19985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PSEFU_RS19990	COG0534	Mate efflux family protein
PSEFU_RS19995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PSEFU_RS20000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PSEFU_RS20010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PSEFU_RS20020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSEFU_RS20025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PSEFU_RS20040	COG1166	arginine decarboxylase activity
PSEFU_RS20045	COG0023	Translation Initiation Factor
PSEFU_RS20095	COG2264	protein methyltransferase activity
PSEFU_RS20105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PSEFU_RS20115	COG0138	bifunctional purine biosynthesis protein purh
PSEFU_RS20130	COG0583	DNA-binding transcription factor activity
PSEFU_RS20140	COG0514	ATP-dependent DNA helicase (RecQ)
PSEFU_RS20145	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PSEFU_RS20150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PSEFU_RS20160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PSEFU_RS20165	COG2203	Gaf domain
PSEFU_RS20165	COG2199	diguanylate cyclase activity
PSEFU_RS20165	COG2200	EAL domain
PSEFU_RS20170	COG4067	protein conserved in archaea
PSEFU_RS20170	COG0189	ligase activity
PSEFU_RS20175	COG0189	ligase activity
PSEFU_RS20200	COG2183	response to ionizing radiation
PSEFU_RS20210	COG2918	glutathione biosynthetic process
PSEFU_RS20225	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS20230	COG0183	Belongs to the thiolase family
PSEFU_RS20235	COG3320	Male sterility
PSEFU_RS20235	COG1022	Amp-dependent synthetase and ligase
PSEFU_RS20240	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS20245	COG1024	Enoyl-CoA hydratase
PSEFU_RS20255	COG2814	Major facilitator Superfamily
PSEFU_RS20295	COG2207	Transcriptional regulator
PSEFU_RS20310	COG2321	neutral zinc metallopeptidase
PSEFU_RS20315	COG1088	dTDP-glucose 4,6-dehydratase activity
PSEFU_RS20320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PSEFU_RS20365	COG1218	3'(2'),5'-bisphosphate nucleotidase
PSEFU_RS20370	COG0494	nUDIX hydrolase
PSEFU_RS20375	COG1011	Hydrolase
PSEFU_RS20390	COG1802	Transcriptional regulator
PSEFU_RS20420	COG4221	oxidoreductase activity
PSEFU_RS20440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PSEFU_RS20445	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PSEFU_RS20460	COG1238	metal cluster binding
PSEFU_RS20470	COG0443	Heat shock 70 kDa protein
PSEFU_RS20485	COG0305	Participates in initiation and elongation during chromosome replication
PSEFU_RS20490	COG0359	binds to the 23S rRNA
PSEFU_RS20500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PSEFU_RS20505	COG0360	Binds together with S18 to 16S ribosomal RNA
PSEFU_RS20510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSEFU_RS20515	COG0557	exoribonuclease II activity
PSEFU_RS20530	COG0840	transmembrane signaling receptor activity
PSEFU_RS20535	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PSEFU_RS20540	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PSEFU_RS20545	COG0330	HflC and HflK could
PSEFU_RS20550	COG0330	HflC and HflK could
PSEFU_RS20555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PSEFU_RS20560	COG1923	regulation of RNA biosynthetic process
PSEFU_RS20565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PSEFU_RS20575	COG0860	N-Acetylmuramoyl-L-alanine amidase
PSEFU_RS20580	COG0802	atpase or kinase
PSEFU_RS20585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PSEFU_RS20585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PSEFU_RS20595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PSEFU_RS20605	COG1162	GTPase activity
PSEFU_RS20615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PSEFU_RS20630	COG0688	phosphatidylethanolamine metabolic process
PSEFU_RS20640	COG2200	EAL domain
PSEFU_RS20665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSEFU_RS20675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSEFU_RS20680	COG0431	NADPH-dependent FMN reductase
PSEFU_RS20685	COG0450	alkyl hydroperoxide reductase
PSEFU_RS20695	COG0417	DNA replication proofreading
PSEFU_RS20705	COG3158	transport of potassium into the cell
PSEFU_RS20710	COG2205	protein histidine kinase activity
PSEFU_RS20715	COG0745	RESPONSE REGULATOR receiver
PSEFU_RS20720	COG1309	transcriptional regulator
PSEFU_RS20725	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS20730	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PSEFU_RS20735	COG0477	Major facilitator Superfamily
PSEFU_RS20740	COG0513	Belongs to the DEAD box helicase family
PSEFU_RS20755	COG2081	HI0933 family
PSEFU_RS20760	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PSEFU_RS20765	COG1760	l-serine dehydratase
PSEFU_RS20785	COG3577	Aspartyl protease
PSEFU_RS20800	COG3150	esterase
PSEFU_RS20805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PSEFU_RS20815	COG0494	nUDIX hydrolase
PSEFU_RS20825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PSEFU_RS20830	COG1538	Outer membrane efflux protein
PSEFU_RS20835	COG1519	Transferase
PSEFU_RS20840	COG0583	DNA-binding transcription factor activity
PSEFU_RS20855	COG0667	Aldo Keto reductase
PSEFU_RS20865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PSEFU_RS20865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PSEFU_RS20880	COG1132	(ABC) transporter
PSEFU_RS20925	COG2755	lipolytic protein G-D-S-L family
PSEFU_RS20925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSEFU_RS20950	COG2192	nodulation
PSEFU_RS20980	COG0438	transferase activity, transferring glycosyl groups
PSEFU_RS20985	COG0859	PFAM glycosyl transferase family 9
PSEFU_RS20995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PSEFU_RS21015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSEFU_RS21030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PSEFU_RS21035	COG1960	acyl-CoA dehydrogenase activity
PSEFU_RS21040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PSEFU_RS21055	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PSEFU_RS21060	COG1671	Belongs to the UPF0178 family
PSEFU_RS21075	COG0488	(ABC) transporter
PSEFU_RS21100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PSEFU_RS21105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PSEFU_RS21110	COG0140	phosphoribosyl-ATP diphosphatase activity
PSEFU_RS21115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSEFU_RS21135	COG0204	Acyl-transferase
PSEFU_RS21145	COG1063	alcohol dehydrogenase
PSEFU_RS21175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSEFU_RS21195	COG1017	nitric oxide dioxygenase activity
PSEFU_RS21195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSEFU_RS21215	COG3246	L-lysine catabolic process to acetate
PSEFU_RS21240	COG1902	pentaerythritol trinitrate reductase activity
PSEFU_RS21240	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSEFU_RS21245	COG2181	nitrate reductase activity
PSEFU_RS21245	COG0247	lactate metabolic process
PSEFU_RS21250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PSEFU_RS21270	COG4175	Glycine betaine
PSEFU_RS21275	COG4176	ABC-type proline glycine betaine transport system permease component
PSEFU_RS21305	COG3829	transcription factor binding
PSEFU_RS21315	COG5583	Uncharacterized small protein (DUF2292)
PSEFU_RS21320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PSEFU_RS21330	COG4208	sulfate ABC transporter
PSEFU_RS21360	COG0584	glycerophosphoryl diester phosphodiesterase
PSEFU_RS21370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PSEFU_RS21395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PSEFU_RS21405	COG0730	response to heat
PSEFU_RS21425	COG0494	nUDIX hydrolase
PSEFU_RS21440	COG3851	Histidine kinase
PSEFU_RS21445	COG2197	response regulator
PSEFU_RS21450	COG2205	protein histidine kinase activity
PSEFU_RS21455	COG2201	protein-glutamate methylesterase activity
PSEFU_RS21465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PSEFU_RS21470	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PSEFU_RS21480	COG3111	PFAM Bacterial OB fold (BOF) protein
PSEFU_RS21485	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSEFU_RS21490	COG0277	FAD linked oxidase domain protein
PSEFU_RS21495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSEFU_RS21525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PSEFU_RS21530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PSEFU_RS21535	COG0747	negative chemotaxis
PSEFU_RS21545	COG2003	Belongs to the UPF0758 family
PSEFU_RS21550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PSEFU_RS21555	COG0756	dUTP diphosphatase activity
PSEFU_RS21565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PSEFU_RS21570	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PSEFU_RS21585	COG0676	glucose-6-phosphate 1-epimerase activity
PSEFU_RS21590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PSEFU_RS21615	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PSEFU_RS21620	COG0735	belongs to the Fur family
PSEFU_RS21625	COG1121	(ABC) transporter
PSEFU_RS21630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSEFU_RS21640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PSEFU_RS21645	COG2011	ABC-type metal ion transport system permease component
PSEFU_RS21675	COG0659	secondary active sulfate transmembrane transporter activity
PSEFU_RS21685	COG0166	Belongs to the GPI family
PSEFU_RS21695	COG1070	Carbohydrate kinase
PSEFU_RS21700	COG0246	Mannitol dehydrogenase
PSEFU_RS21715	COG1175	transmembrane transport
PSEFU_RS21720	COG1653	transport
PSEFU_RS21765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSEFU_RS21795	COG2207	Transcriptional regulator
PSEFU_RS21810	COG0277	FAD linked oxidase domain protein
PSEFU_RS21835	COG0339	signal peptide processing
PSEFU_RS21840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PSEFU_RS21865	COG1418	mRNA catabolic process
PSEFU_RS21950	COG0765	amino acid transport
PSEFU_RS21955	COG0765	amino acid transport
PSEFU_RS21960	COG1126	abc transporter atp-binding protein
PSEFU_RS21990	COG1595	DNA-templated transcription, initiation
PSEFU_RS21995	COG0583	DNA-binding transcription factor activity
PSEFU_RS22020	COG1115	amino acid carrier protein
PSEFU_RS22025	COG0252	asparaginase activity
PSEFU_RS22035	COG2066	Belongs to the glutaminase family
PSEFU_RS22040	COG2040	homocysteine
PSEFU_RS22045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSEFU_RS22050	COG0765	amino acid transport
PSEFU_RS22065	COG1115	amino acid carrier protein
PSEFU_RS22075	COG2391	methyltransferase activity
PSEFU_RS22085	COG0511	ligase activity, forming carbon-carbon bonds
PSEFU_RS22085	COG5016	pyruvate
PSEFU_RS22090	COG0439	Biotin carboxylase
PSEFU_RS22095	COG0583	DNA-binding transcription factor activity
PSEFU_RS22105	COG2989	Protein conserved in bacteria
PSEFU_RS22135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PSEFU_RS22135	COG2207	Transcriptional regulator
PSEFU_RS22140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSEFU_RS22145	COG1012	belongs to the aldehyde dehydrogenase family
PSEFU_RS22185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSEFU_RS22190	COG0488	(ABC) transporter
PSEFU_RS22280	COG4964	Belongs to the GSP D family
PSEFU_RS22300	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PSEFU_RS22305	COG1752	Esterase of the alpha-beta hydrolase superfamily
PSEFU_RS22325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSEFU_RS22345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PSEFU_RS22375	COG0024	Methionine aminopeptidase
PSEFU_RS22380	COG2364	Membrane
PSEFU_RS22385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PSEFU_RS22390	COG1349	DNA-binding transcription factor activity
PSEFU_RS22395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PSEFU_RS22400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PSEFU_RS22405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PSEFU_RS22410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PSEFU_RS22415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PSEFU_RS22420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSEFU_RS22425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PSEFU_RS22440	COG3312	ion transport
PSEFU_RS22445	COG1475	DNA binding
PSEFU_RS22450	COG1192	Involved in chromosome partitioning
PSEFU_RS22455	COG0357	Ribosomal RNA small subunit methyltransferase G
PSEFU_RS22460	COG0445	tRNA wobble uridine modification
PSEFU_RS22475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PSEFU_RS22480	COG0706	membrane insertase activity
PSEFU_RS22485	COG0594	ribonuclease P activity
PSEFU_RS22490	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PSEFU_RS22525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PSEFU_RS22535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein