locus-tag	class	description
JN757_RS00010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JN757_RS00015	COG0427	acetyl-CoA hydrolase
JN757_RS00030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JN757_RS00040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS00055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS00065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN757_RS00075	COG3188	usher protein
JN757_RS00080	COG3121	Chaperone
JN757_RS00090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN757_RS00100	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS00110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JN757_RS00115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JN757_RS00120	COG0747	negative chemotaxis
JN757_RS00125	COG2003	Belongs to the UPF0758 family
JN757_RS00130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JN757_RS00135	COG0756	dUTP diphosphatase activity
JN757_RS00140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN757_RS00145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JN757_RS00150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JN757_RS00155	COG0708	Exodeoxyribonuclease III
JN757_RS00160	COG0786	glutamate:sodium symporter activity
JN757_RS00170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JN757_RS00175	COG1561	YicC-like family, N-terminal region
JN757_RS00180	COG0194	GDP metabolic process
JN757_RS00185	COG1758	RNA polymerase activity
JN757_RS00190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JN757_RS00205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN757_RS00215	COG0848	biopolymer transport protein
JN757_RS00225	COG0583	DNA-binding transcription factor activity
JN757_RS00230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JN757_RS00290	COG3755	Protein conserved in bacteria
JN757_RS00300	COG3755	Protein conserved in bacteria
JN757_RS00325	COG0515	serine threonine protein kinase
JN757_RS00325	COG2815	serine threonine protein kinase
JN757_RS00365	COG2204	response regulator
JN757_RS00470	COG3161	chorismate lyase activity
JN757_RS00475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JN757_RS00495	COG1253	flavin adenine dinucleotide binding
JN757_RS00500	COG0739	heme binding
JN757_RS00510	COG0704	Plays a role in the regulation of phosphate uptake
JN757_RS00515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JN757_RS00520	COG0573	inorganic phosphate transmembrane transporter activity
JN757_RS00545	COG0477	Major facilitator Superfamily
JN757_RS00550	COG1607	acyl-coa hydrolase
JN757_RS00580	COG0583	DNA-binding transcription factor activity
JN757_RS00585	COG1027	Aspartate ammonia-lyase
JN757_RS00590	COG1115	amino acid carrier protein
JN757_RS00595	COG0252	asparaginase activity
JN757_RS00650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS00655	COG0765	amino acid transport
JN757_RS00680	COG0511	ligase activity, forming carbon-carbon bonds
JN757_RS00680	COG5016	pyruvate
JN757_RS00685	COG0439	Biotin carboxylase
JN757_RS00690	COG0583	DNA-binding transcription factor activity
JN757_RS00710	COG0210	DNA helicase
JN757_RS00725	COG4651	solute:proton antiporter activity
JN757_RS00725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JN757_RS00730	COG1607	acyl-coa hydrolase
JN757_RS00735	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JN757_RS00745	COG0523	cobalamin synthesis protein
JN757_RS00770	COG1469	GTP cyclohydrolase I activity
JN757_RS00785	COG0803	Belongs to the bacterial solute-binding protein 9 family
JN757_RS00795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN757_RS00800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN757_RS00805	COG2217	Heavy metal translocating P-type atpase
JN757_RS00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN757_RS00830	COG1522	sequence-specific DNA binding
JN757_RS00835	COG1280	lysine exporter protein (LysE YggA)
JN757_RS00850	COG2226	methyltransferase
JN757_RS00860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JN757_RS00905	COG0438	transferase activity, transferring glycosyl groups
JN757_RS00915	COG1017	nitric oxide dioxygenase activity
JN757_RS00915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN757_RS00920	COG0625	glutathione transferase activity
JN757_RS00925	COG0583	DNA-binding transcription factor activity
JN757_RS00930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JN757_RS00935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JN757_RS00945	COG3135	benzoate transporter
JN757_RS00950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JN757_RS00995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN757_RS01000	COG1349	DNA-binding transcription factor activity
JN757_RS01005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JN757_RS01010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JN757_RS01015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JN757_RS01020	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JN757_RS01025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JN757_RS01030	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JN757_RS01035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JN757_RS01045	COG0356	it plays a direct role in the translocation of protons across the membrane
JN757_RS01050	COG3312	ion transport
JN757_RS01055	COG1475	DNA binding
JN757_RS01060	COG1192	Involved in chromosome partitioning
JN757_RS01065	COG0357	Ribosomal RNA small subunit methyltransferase G
JN757_RS01070	COG0445	tRNA wobble uridine modification
JN757_RS01075	COG1595	DNA-templated transcription, initiation
JN757_RS01080	COG3712	iron ion homeostasis
JN757_RS01085	COG4774	siderophore transport
JN757_RS01090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JN757_RS01095	COG0706	membrane insertase activity
JN757_RS01100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JN757_RS01105	COG0594	ribonuclease P activity
JN757_RS01110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JN757_RS01115	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JN757_RS01120	COG0592	DNA-directed DNA polymerase activity
JN757_RS01125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN757_RS01130	COG0187	DNA topoisomerase II activity
JN757_RS01135	COG0745	RESPONSE REGULATOR receiver
JN757_RS01140	COG5002	protein histidine kinase activity
JN757_RS01150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JN757_RS01155	COG0751	glycine-tRNA ligase activity
JN757_RS01160	COG0752	glycyl-tRNA synthetase alpha subunit
JN757_RS01165	COG2818	Glycosylase
JN757_RS01185	COG0569	domain protein
JN757_RS01190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JN757_RS01195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JN757_RS01200	COG0242	peptide deformylase activity
JN757_RS01210	COG0758	DNA mediated transformation
JN757_RS01215	COG0009	L-threonylcarbamoyladenylate synthase
JN757_RS01230	COG0408	coproporphyrinogen oxidase activity
JN757_RS01235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN757_RS01250	COG3119	arylsulfatase activity
JN757_RS01270	COG2851	Citrate transporter
JN757_RS01275	COG0861	Integral membrane protein TerC family
JN757_RS01295	COG1283	sodium-dependent phosphate transmembrane transporter activity
JN757_RS01300	COG0612	Peptidase, M16
JN757_RS01310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN757_RS01315	COG1127	ABC transporter
JN757_RS01330	COG0700	Nucleoside recognition
JN757_RS01335	COG1301	dicarboxylic acid transport
JN757_RS01345	COG5487	UPF0391 membrane protein
JN757_RS01355	COG2204	response regulator
JN757_RS01360	COG5002	protein histidine kinase activity
JN757_RS01365	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JN757_RS01370	COG3023	N-Acetylmuramoyl-L-alanine amidase
JN757_RS01385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JN757_RS01400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JN757_RS01420	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JN757_RS01425	COG0735	belongs to the Fur family
JN757_RS01430	COG1121	(ABC) transporter
JN757_RS01435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN757_RS01450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JN757_RS01455	COG2011	ABC-type metal ion transport system permease component
JN757_RS01470	COG0109	protoheme IX farnesyltransferase activity
JN757_RS01500	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JN757_RS01505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN757_RS01510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN757_RS01520	COG0659	secondary active sulfate transmembrane transporter activity
JN757_RS01565	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JN757_RS01570	COG0339	signal peptide processing
JN757_RS01575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JN757_RS01605	COG1764	response to oxidative stress
JN757_RS01610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN757_RS01620	COG3360	Dodecin
JN757_RS01635	COG0133	tryptophan synthase activity
JN757_RS01640	COG0159	tryptophan synthase activity
JN757_RS01670	COG0427	acetyl-CoA hydrolase
JN757_RS01690	COG0583	DNA-binding transcription factor activity
JN757_RS01700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN757_RS01745	COG3712	iron ion homeostasis
JN757_RS01750	COG1595	DNA-templated transcription, initiation
JN757_RS01755	COG0840	transmembrane signaling receptor activity
JN757_RS01765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN757_RS01790	COG5001	Diguanylate cyclase
JN757_RS01790	COG3300	MHYT domain
JN757_RS01805	COG1538	Outer membrane efflux protein
JN757_RS01810	COG2274	protein secretion by the type I secretion system
JN757_RS01815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS01820	COG2175	clavaminate synthase activity
JN757_RS01825	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN757_RS01830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN757_RS01875	COG1289	transmembrane transporter activity
JN757_RS01885	COG1566	PFAM secretion protein HlyD family protein
JN757_RS01900	COG5339	Protein conserved in bacteria
JN757_RS01905	COG0457	Tetratricopeptide repeat
JN757_RS01910	COG1649	PFAM Uncharacterised BCR, COG1649
JN757_RS01910	COG0726	polysaccharide deacetylase
JN757_RS01915	COG1215	transferase activity, transferring glycosyl groups
JN757_RS01925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN757_RS01945	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS01950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JN757_RS01955	COG0745	RESPONSE REGULATOR receiver
JN757_RS01960	COG2199	diguanylate cyclase activity
JN757_RS01980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JN757_RS01990	COG4208	sulfate ABC transporter
JN757_RS01995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JN757_RS02050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN757_RS02080	COG4771	TonB-dependent receptor
JN757_RS02120	COG0765	amino acid transport
JN757_RS02125	COG0765	amino acid transport
JN757_RS02130	COG1126	abc transporter atp-binding protein
JN757_RS02135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS02140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JN757_RS02155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN757_RS02175	COG2011	ABC-type metal ion transport system permease component
JN757_RS02180	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JN757_RS02185	COG1464	Belongs to the NlpA lipoprotein family
JN757_RS02210	COG1126	abc transporter atp-binding protein
JN757_RS02215	COG0765	amino acid transport
JN757_RS02220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS02230	COG1045	serine acetyltransferase
JN757_RS02235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JN757_RS02250	COG1609	Transcriptional regulator
JN757_RS02260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN757_RS02265	COG0667	Aldo Keto reductase
JN757_RS02270	COG2175	clavaminate synthase activity
JN757_RS02275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN757_RS02280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JN757_RS02285	COG4521	taurine ABC transporter
JN757_RS02290	COG2918	glutathione biosynthetic process
JN757_RS02300	COG2183	response to ionizing radiation
JN757_RS02315	COG0189	ligase activity
JN757_RS02320	COG4067	protein conserved in archaea
JN757_RS02320	COG0189	ligase activity
JN757_RS02325	COG2200	EAL domain
JN757_RS02325	COG2199	diguanylate cyclase activity
JN757_RS02325	COG3287	FIST C domain
JN757_RS02330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JN757_RS02340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JN757_RS02345	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JN757_RS02380	COG0514	ATP-dependent DNA helicase (RecQ)
JN757_RS02385	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN757_RS02385	COG1024	Enoyl-CoA hydratase
JN757_RS02400	COG0243	molybdopterin cofactor binding
JN757_RS02405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JN757_RS02410	COG0583	DNA-binding transcription factor activity
JN757_RS02415	COG1652	LysM domain
JN757_RS02420	COG1011	Hydrolase
JN757_RS02425	COG0494	nUDIX hydrolase
JN757_RS02430	COG1218	3'(2'),5'-bisphosphate nucleotidase
JN757_RS02455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JN757_RS02465	COG2957	Belongs to the agmatine deiminase family
JN757_RS02520	COG5642	Protein of unknown function (DUF2384)
JN757_RS02570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS02600	COG4804	nuclease activity
JN757_RS02615	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JN757_RS02620	COG1194	a g-specific adenine glycosylase
JN757_RS02635	COG2223	nitrite transmembrane transporter activity
JN757_RS02640	COG0131	Imidazoleglycerol-phosphate dehydratase
JN757_RS02645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JN757_RS02655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JN757_RS02660	COG0107	imidazoleglycerol-phosphate synthase activity
JN757_RS02680	COG2861	carbohydrate metabolic process
JN757_RS02685	COG0793	Belongs to the peptidase S41A family
JN757_RS02690	COG4942	peptidase
JN757_RS02695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JN757_RS02710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JN757_RS02715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JN757_RS02740	COG3852	Histidine kinase
JN757_RS02760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN757_RS02760	COG0301	tRNA thio-modification
JN757_RS02765	COG1217	gtp-binding protein TYPA
JN757_RS02775	COG0058	SHG alpha-glucan phosphorylase activity
JN757_RS02790	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JN757_RS02810	COG3040	lipid binding
JN757_RS02815	COG0402	S-adenosylhomocysteine deaminase activity
JN757_RS02820	COG2188	Transcriptional regulator
JN757_RS02830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JN757_RS02835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JN757_RS02845	COG4176	ABC-type proline glycine betaine transport system permease component
JN757_RS02850	COG4175	Glycine betaine
JN757_RS02850	COG0517	IMP dehydrogenase activity
JN757_RS02855	COG2986	histidine ammonia-lyase
JN757_RS02860	COG2986	histidine ammonia-lyase
JN757_RS02865	COG1228	amidohydrolase
JN757_RS02875	COG0596	Alpha beta hydrolase
JN757_RS02880	COG1490	D-aminoacyl-tRNA deacylase activity
JN757_RS02885	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JN757_RS02890	COG2943	transferase activity, transferring hexosyl groups
JN757_RS02895	COG0840	transmembrane signaling receptor activity
JN757_RS02910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN757_RS02915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JN757_RS02920	COG0140	phosphoribosyl-ATP diphosphatase activity
JN757_RS02925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JN757_RS02930	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JN757_RS02940	COG2226	methyltransferase
JN757_RS02960	COG1309	transcriptional regulator
JN757_RS02985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JN757_RS02990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JN757_RS03000	COG0018	arginyl-trna synthetase
JN757_RS03005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JN757_RS03010	COG0254	rRNA binding
JN757_RS03020	COG0281	malic enzyme
JN757_RS03055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JN757_RS03060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JN757_RS03070	COG0070	glutamate synthase
JN757_RS03070	COG0069	glutamate synthase activity
JN757_RS03070	COG0067	glutamate synthase
JN757_RS03075	COG0493	'glutamate synthase
JN757_RS03080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JN757_RS03085	COG2814	Major facilitator Superfamily
JN757_RS03090	COG0583	DNA-binding transcription factor activity
JN757_RS03105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN757_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS03120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN757_RS03130	COG2226	methyltransferase
JN757_RS03160	COG2986	histidine ammonia-lyase
JN757_RS03175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JN757_RS03185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN757_RS03190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN757_RS03205	COG1192	Involved in chromosome partitioning
JN757_RS03210	COG3118	belongs to the thioredoxin family
JN757_RS03215	COG5499	transcription regulator containing HTH domain
JN757_RS03220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JN757_RS03225	COG3264	Mechanosensitive ion channel
JN757_RS03225	COG1196	nuclear chromosome segregation
JN757_RS03230	COG3263	regulation of cellular component size
JN757_RS03255	COG1960	acyl-CoA dehydrogenase activity
JN757_RS03260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JN757_RS03260	COG0506	proline dehydrogenase activity
JN757_RS03260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JN757_RS03265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JN757_RS03285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JN757_RS03290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN757_RS03315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JN757_RS03320	COG0859	PFAM glycosyl transferase family 9
JN757_RS03325	COG0859	PFAM glycosyl transferase family 9
JN757_RS03330	COG0438	transferase activity, transferring glycosyl groups
JN757_RS03355	COG2192	nodulation
JN757_RS03360	COG1215	transferase activity, transferring glycosyl groups
JN757_RS03375	COG1132	(ABC) transporter
JN757_RS03390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JN757_RS03390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JN757_RS03415	COG0667	Aldo Keto reductase
JN757_RS03430	COG0583	DNA-binding transcription factor activity
JN757_RS03435	COG1519	Transferase
JN757_RS03440	COG1538	Outer membrane efflux protein
JN757_RS03445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JN757_RS03460	COG0494	nUDIX hydrolase
JN757_RS03470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JN757_RS03475	COG3150	esterase
JN757_RS03515	COG3830	Belongs to the UPF0237 family
JN757_RS03515	COG0560	Phosphoserine phosphatase
JN757_RS03525	COG0688	phosphatidylethanolamine metabolic process
JN757_RS03565	COG1162	GTPase activity
JN757_RS03570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JN757_RS03580	COG2860	membrane
JN757_RS03610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JN757_RS03610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JN757_RS03615	COG0802	atpase or kinase
JN757_RS03620	COG0860	N-Acetylmuramoyl-L-alanine amidase
JN757_RS03625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JN757_RS03630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JN757_RS03635	COG1923	regulation of RNA biosynthetic process
JN757_RS03640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JN757_RS03645	COG0330	HflC and HflK could
JN757_RS03650	COG0330	HflC and HflK could
JN757_RS03655	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JN757_RS03660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JN757_RS03670	COG1178	ABC-type Fe3 transport system permease component
JN757_RS03690	COG0557	exoribonuclease II activity
JN757_RS03695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JN757_RS03700	COG0360	Binds together with S18 to 16S ribosomal RNA
JN757_RS03705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JN757_RS03715	COG0359	binds to the 23S rRNA
JN757_RS03720	COG0305	Participates in initiation and elongation during chromosome replication
JN757_RS03745	COG1032	radical SAM domain protein
JN757_RS03755	COG2307	Protein conserved in bacteria
JN757_RS03755	COG2308	Evidence 4 Homologs of previously reported genes of
JN757_RS03780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JN757_RS03785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JN757_RS03790	COG0583	DNA-binding transcription factor activity
JN757_RS03795	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS03800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS03830	COG4221	oxidoreductase activity
JN757_RS03845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JN757_RS03850	COG0830	nickel cation binding
JN757_RS03855	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JN757_RS03860	COG1309	transcriptional regulator
JN757_RS03870	COG2982	Protein involved in outer membrane biogenesis
JN757_RS03880	COG0583	DNA-binding transcription factor activity
JN757_RS03885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JN757_RS03895	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JN757_RS03900	COG0697	spore germination
JN757_RS03920	COG0443	Heat shock 70 kDa protein
JN757_RS03925	COG0484	heat shock protein binding
JN757_RS03930	COG0789	Transcriptional regulator
JN757_RS03945	COG0804	urea catabolic process
JN757_RS03950	COG0832	Belongs to the urease beta subunit family
JN757_RS03965	COG0831	urea catabolic process
JN757_RS03970	COG0829	nickel cation binding
JN757_RS03980	COG0411	ABC transporter
JN757_RS03995	COG0683	leucine binding
JN757_RS04040	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JN757_RS04065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN757_RS04090	COG2095	MarC family integral membrane protein
JN757_RS04100	COG0151	Belongs to the GarS family
JN757_RS04105	COG0138	bifunctional purine biosynthesis protein purh
JN757_RS04115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JN757_RS04125	COG2264	protein methyltransferase activity
JN757_RS04130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JN757_RS04190	COG0023	Translation Initiation Factor
JN757_RS04195	COG1166	arginine decarboxylase activity
JN757_RS04215	COG0534	Mate efflux family protein
JN757_RS04235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JN757_RS04305	COG4964	Belongs to the GSP D family
JN757_RS04335	COG2030	dehydratase
JN757_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS04345	COG0183	Belongs to the thiolase family
JN757_RS04350	COG0840	transmembrane signaling receptor activity
JN757_RS04370	COG2217	Heavy metal translocating P-type atpase
JN757_RS04385	COG2814	Major facilitator Superfamily
JN757_RS04395	COG0604	alcohol dehydrogenase
JN757_RS04405	COG0583	DNA-binding transcription factor activity
JN757_RS04415	COG0477	Major facilitator Superfamily
JN757_RS04420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JN757_RS04435	COG0387	Pfam Sodium calcium exchanger
JN757_RS04450	COG1079	Belongs to the binding-protein-dependent transport system permease family
JN757_RS04455	COG4603	Belongs to the binding-protein-dependent transport system permease family
JN757_RS04460	COG3845	ABC transporter
JN757_RS04465	COG1739	Uncharacterized protein family UPF0029
JN757_RS04470	COG1309	transcriptional regulator
JN757_RS04475	COG2233	PERMEase
JN757_RS04520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JN757_RS04525	COG1074	ATP-dependent DNA helicase activity
JN757_RS04530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JN757_RS04540	COG2199	diguanylate cyclase activity
JN757_RS04545	COG2885	chlorophyll binding
JN757_RS04570	COG0583	DNA-binding transcription factor activity
JN757_RS04585	COG2249	NAD(P)H dehydrogenase (quinone) activity
JN757_RS04590	COG0583	DNA-binding transcription factor activity
JN757_RS04600	COG2610	gluconate transmembrane transporter activity
JN757_RS04610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JN757_RS04630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JN757_RS04635	COG1070	Carbohydrate kinase
JN757_RS04640	COG0840	transmembrane signaling receptor activity
JN757_RS04780	COG0247	lactate metabolic process
JN757_RS04785	COG1620	l-lactate permease
JN757_RS04795	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JN757_RS04800	COG0733	neurotransmitter:sodium symporter activity
JN757_RS04810	COG2914	Belongs to the UPF0125 (RnfH) family
JN757_RS04815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN757_RS04820	COG0735	belongs to the Fur family
JN757_RS04825	COG0497	DNA recombination
JN757_RS04830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JN757_RS04835	COG0443	Heat shock 70 kDa protein
JN757_RS04840	COG0484	heat shock protein binding
JN757_RS04845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JN757_RS04850	COG0505	Belongs to the CarA family
JN757_RS04855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JN757_RS04860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN757_RS04875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JN757_RS04880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JN757_RS04885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JN757_RS04890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JN757_RS04895	COG0149	triose-phosphate isomerase activity
JN757_RS04900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JN757_RS04920	COG0195	Participates in both transcription termination and antitermination
JN757_RS04925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JN757_RS04930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JN757_RS04935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JN757_RS04940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JN757_RS04945	COG1185	polyribonucleotide nucleotidyltransferase activity
JN757_RS04975	COG3023	N-Acetylmuramoyl-L-alanine amidase
JN757_RS04990	COG0084	hydrolase, TatD family'
JN757_RS04995	COG1609	Transcriptional regulator
JN757_RS05000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN757_RS05000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN757_RS05005	COG1105	Belongs to the carbohydrate kinase PfkB family
JN757_RS05010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JN757_RS05010	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JN757_RS05010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JN757_RS05020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JN757_RS05025	COG4774	siderophore transport
JN757_RS05030	COG3128	pkhd-type hydroxylase
JN757_RS05050	COG0019	diaminopimelate decarboxylase activity
JN757_RS05075	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JN757_RS05090	COG4608	Belongs to the ABC transporter superfamily
JN757_RS05095	COG0444	Belongs to the ABC transporter superfamily
JN757_RS05100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JN757_RS05105	COG0601	transmembrane transport
JN757_RS05110	COG0747	negative chemotaxis
JN757_RS05120	COG0747	negative chemotaxis
JN757_RS05125	COG0747	negative chemotaxis
JN757_RS05130	COG0747	negative chemotaxis
JN757_RS05150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
JN757_RS05155	COG4178	(ABC) transporter
JN757_RS05175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN757_RS05185	COG2271	Major facilitator Superfamily
JN757_RS05190	COG2721	sulfolactate sulfo-lyase activity
JN757_RS05200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN757_RS05210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JN757_RS05215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JN757_RS05220	COG0154	amidase activity
JN757_RS05225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JN757_RS05230	COG1077	Cell shape determining protein MreB Mrl
JN757_RS05235	COG1792	Involved in formation and maintenance of cell shape
JN757_RS05240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JN757_RS05245	COG0424	maF-like protein
JN757_RS05250	COG1530	ribonuclease E activity
JN757_RS05260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN757_RS05265	COG0312	modulator of DNA gyrase
JN757_RS05270	COG3028	Belongs to the UPF0307 family
JN757_RS05275	COG0312	modulator of DNA gyrase
JN757_RS05310	COG1660	Displays ATPase and GTPase activities
JN757_RS05320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JN757_RS05325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JN757_RS05330	COG1137	ATPase activity
JN757_RS05335	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JN757_RS05345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JN757_RS05355	COG1127	ABC transporter
JN757_RS05360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JN757_RS05365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JN757_RS05380	COG5007	Belongs to the BolA IbaG family
JN757_RS05385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JN757_RS05390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JN757_RS05395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JN757_RS05400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN757_RS05415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN757_RS05425	COG0175	sulfate reduction
JN757_RS05435	COG0204	Acyl-transferase
JN757_RS05440	COG0280	phosphate acetyltransferase
JN757_RS05440	COG0857	belongs to the CobB CobQ family
JN757_RS05455	COG0386	Belongs to the glutathione peroxidase family
JN757_RS05485	COG1403	HNH endonuclease
JN757_RS05490	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JN757_RS05495	COG0492	ferredoxin-NADP+ reductase activity
JN757_RS05510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JN757_RS05515	COG0302	gtp cyclohydrolase
JN757_RS05530	COG0789	Transcriptional regulator
JN757_RS05540	COG1366	Belongs to the anti-sigma-factor antagonist family
JN757_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS05595	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JN757_RS05600	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN757_RS05620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JN757_RS05640	COG1760	l-serine dehydratase
JN757_RS05645	COG0583	DNA-binding transcription factor activity
JN757_RS05665	COG4772	TonB-dependent receptor
JN757_RS05670	COG3712	iron ion homeostasis
JN757_RS05675	COG1595	DNA-templated transcription, initiation
JN757_RS05690	COG3712	iron ion homeostasis
JN757_RS05695	COG4774	siderophore transport
JN757_RS05705	COG0697	spore germination
JN757_RS05715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN757_RS05725	COG0583	DNA-binding transcription factor activity
JN757_RS05745	COG1566	PFAM secretion protein HlyD family protein
JN757_RS05755	COG0300	oxidoreductase activity
JN757_RS05770	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JN757_RS05770	COG0662	Cupin 2, conserved barrel domain protein
JN757_RS05785	COG1696	Membrane protein involved in D-alanine export
JN757_RS05800	COG3420	alginic acid biosynthetic process
JN757_RS05810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JN757_RS05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS05820	COG1215	transferase activity, transferring glycosyl groups
JN757_RS05830	COG3022	response to hydroperoxide
JN757_RS05840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JN757_RS05845	COG0315	cyclic pyranopterin monophosphate synthase activity
JN757_RS05850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JN757_RS05860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS05880	COG0513	Belongs to the DEAD box helicase family
JN757_RS05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS05895	COG4597	amino acid ABC transporter
JN757_RS05900	COG0765	amino acid transport
JN757_RS05905	COG1126	abc transporter atp-binding protein
JN757_RS05920	COG2186	Transcriptional regulator
JN757_RS05925	COG2807	transmembrane transport
JN757_RS05935	COG2827	Endonuclease containing a URI domain
JN757_RS05950	COG3081	Nucleoid-associated protein
JN757_RS05960	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JN757_RS05965	COG0525	valine-tRNA ligase activity
JN757_RS05985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JN757_RS05990	COG0795	lipopolysaccharide-transporting ATPase activity
JN757_RS05995	COG0795	lipopolysaccharide-transporting ATPase activity
JN757_RS06000	COG0481	GTPase activity
JN757_RS06005	COG0681	Belongs to the peptidase S26 family
JN757_RS06010	COG0571	ribonuclease III activity
JN757_RS06015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JN757_RS06020	COG1381	Involved in DNA repair and RecF pathway recombination
JN757_RS06025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JN757_RS06030	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JN757_RS06035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JN757_RS06035	COG0047	phosphoribosylformylglycinamidine synthase activity
JN757_RS06040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JN757_RS06050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JN757_RS06050	COG1263	PTS System
JN757_RS06050	COG2190	(PTS) system
JN757_RS06055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JN757_RS06055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JN757_RS06060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JN757_RS06065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JN757_RS06070	COG2188	Transcriptional regulator
JN757_RS06085	COG0494	nUDIX hydrolase
JN757_RS06105	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JN757_RS06110	COG0477	Major facilitator Superfamily
JN757_RS06115	COG4536	flavin adenine dinucleotide binding
JN757_RS06125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JN757_RS06130	COG0228	four-way junction DNA binding
JN757_RS06135	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JN757_RS06140	COG0336	Belongs to the RNA methyltransferase TrmD family
JN757_RS06145	COG0335	large ribosomal subunit rRNA binding
JN757_RS06155	COG4974	Belongs to the 'phage' integrase family
JN757_RS06175	COG2205	protein histidine kinase activity
JN757_RS06175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS06195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN757_RS06210	COG1902	pentaerythritol trinitrate reductase activity
JN757_RS06215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
JN757_RS06230	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS06260	COG2732	(Barnase) inhibitor
JN757_RS06300	COG3209	COG3209 Rhs family protein
JN757_RS06330	COG0457	Tetratricopeptide repeat
JN757_RS06330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JN757_RS06345	COG2201	protein-glutamate methylesterase activity
JN757_RS06350	COG5001	Diguanylate cyclase
JN757_RS06350	COG3706	GGDEF domain
JN757_RS06350	COG4251	negative regulation of phosphorylation
JN757_RS06350	COG2203	Gaf domain
JN757_RS06360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JN757_RS06380	COG1073	alpha beta
JN757_RS06405	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JN757_RS06410	COG0563	adenylate kinase activity
JN757_RS06445	COG0742	ribosomal rna small subunit methyltransferase
JN757_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS06475	COG2937	Belongs to the GPAT DAPAT family
JN757_RS06490	COG2226	methyltransferase
JN757_RS06495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JN757_RS06500	COG1215	transferase activity, transferring glycosyl groups
JN757_RS06505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JN757_RS06515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JN757_RS06520	COG2171	N-acyltransferase activity
JN757_RS06525	COG1393	Belongs to the ArsC family
JN757_RS06530	COG0025	NhaP-type Na H and K H
JN757_RS06540	COG0436	Aminotransferase
JN757_RS06545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JN757_RS06550	COG0024	Methionine aminopeptidase
JN757_RS06555	COG0052	Belongs to the universal ribosomal protein uS2 family
JN757_RS06560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JN757_RS06565	COG0528	UMP kinase activity
JN757_RS06570	COG0233	cytoplasmic translational termination
JN757_RS06575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JN757_RS06585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JN757_RS06595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN757_RS06605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN757_RS06610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JN757_RS06615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN757_RS06620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN757_RS06625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JN757_RS06630	COG0587	DNA-directed DNA polymerase activity
JN757_RS06635	COG0825	malonyl-CoA metabolic process
JN757_RS06640	COG0037	tRNA processing
JN757_RS06645	COG0504	CTP synthase activity
JN757_RS06650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JN757_RS06655	COG0148	phosphopyruvate hydratase activity
JN757_RS06665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JN757_RS06675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JN757_RS06680	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JN757_RS06685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JN757_RS06690	COG0585	pseudouridine synthase activity
JN757_RS06695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JN757_RS06700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JN757_RS06715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JN757_RS06720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JN757_RS06825	COG4386	tail sheath protein
JN757_RS06860	COG4381	Mu-like prophage protein gp46
JN757_RS06905	COG3179	chitinase
JN757_RS06915	COG1546	Belongs to the CinA family
JN757_RS06920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JN757_RS06925	COG2137	regulation of response to DNA damage stimulus
JN757_RS06945	COG3148	PFAM DTW domain containing protein
JN757_RS06960	COG0583	DNA-binding transcription factor activity
JN757_RS06980	COG4807	Protein conserved in bacteria
JN757_RS06995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN757_RS07000	COG3158	transport of potassium into the cell
JN757_RS07030	COG0392	lysyltransferase activity
JN757_RS07030	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JN757_RS07045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JN757_RS07055	COG0442	prolyl-tRNA aminoacylation
JN757_RS07060	COG2211	Major facilitator Superfamily
JN757_RS07075	COG1278	Cold shock
JN757_RS07080	COG0717	Belongs to the dCTP deaminase family
JN757_RS07095	COG1201	RNA secondary structure unwinding
JN757_RS07100	COG4598	ABC transporter
JN757_RS07125	COG1793	dna ligase
JN757_RS07135	COG2366	antibiotic biosynthetic process
JN757_RS07145	COG0653	protein targeting
JN757_RS07155	COG3012	SEC-C Motif Domain Protein
JN757_RS07190	COG1199	ATP-dependent helicase activity
JN757_RS07200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JN757_RS07205	COG2885	chlorophyll binding
JN757_RS07210	COG0259	pyridoxamine-phosphate oxidase activity
JN757_RS07235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JN757_RS07245	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JN757_RS07265	COG0583	DNA-binding transcription factor activity
JN757_RS07280	COG3220	belongs to the UPF0276 family
JN757_RS07325	COG2084	Dehydrogenase
JN757_RS07335	COG0727	PFAM Uncharacterised protein family (UPF0153)
JN757_RS07340	COG2271	Major facilitator Superfamily
JN757_RS07345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JN757_RS07365	COG0306	phosphate transporter
JN757_RS07375	COG1414	Transcriptional regulator
JN757_RS07380	COG2814	Major facilitator Superfamily
JN757_RS07385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JN757_RS07390	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JN757_RS07395	COG0183	Belongs to the thiolase family
JN757_RS07400	COG3485	protocatechuate 3,4-dioxygenase
JN757_RS07405	COG3485	protocatechuate 3,4-dioxygenase
JN757_RS07410	COG0477	Major facilitator Superfamily
JN757_RS07420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN757_RS07425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN757_RS07445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS07455	COG1902	pentaerythritol trinitrate reductase activity
JN757_RS07460	COG2814	Major facilitator Superfamily
JN757_RS07505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN757_RS07515	COG1704	LemA family
JN757_RS07520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JN757_RS07535	COG0697	spore germination
JN757_RS07540	COG0693	protein deglycase activity
JN757_RS07555	COG1454	alcohol dehydrogenase
JN757_RS07610	COG2267	carboxylic ester hydrolase activity
JN757_RS07635	COG0439	Biotin carboxylase
JN757_RS07650	COG1116	anion transmembrane transporter activity
JN757_RS07675	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JN757_RS07720	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JN757_RS07750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JN757_RS07755	COG4783	chaperone-mediated protein folding
JN757_RS07760	COG0425	Belongs to the sulfur carrier protein TusA family
JN757_RS07770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JN757_RS07780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN757_RS07785	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JN757_RS07790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JN757_RS07795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JN757_RS07815	COG3920	Histidine kinase
JN757_RS07815	COG2202	Pas domain
JN757_RS07830	COG0463	Glycosyl transferase, family 2
JN757_RS07865	COG2807	transmembrane transport
JN757_RS07870	COG2194	sulfuric ester hydrolase activity
JN757_RS07880	COG3100	YcgL domain-containing protein
JN757_RS07890	COG2983	Belongs to the UPF0260 family
JN757_RS07925	COG1770	oligopeptidase
JN757_RS07935	COG0121	glutamine amidotransferase
JN757_RS07945	COG0583	DNA-binding transcription factor activity
JN757_RS07950	COG2814	Major facilitator Superfamily
JN757_RS07955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JN757_RS07960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JN757_RS07965	COG1984	allophanate hydrolase subunit 2
JN757_RS07980	COG0542	response to heat
JN757_RS08000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN757_RS08030	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
JN757_RS08035	COG1643	Atp-dependent helicase
JN757_RS08045	COG1595	DNA-templated transcription, initiation
JN757_RS08055	COG2188	Transcriptional regulator
JN757_RS08065	COG1132	(ABC) transporter
JN757_RS08075	COG2267	carboxylic ester hydrolase activity
JN757_RS08090	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JN757_RS08100	COG0668	transmembrane transport
JN757_RS08105	COG0513	Belongs to the DEAD box helicase family
JN757_RS08145	COG2996	Protein conserved in bacteria
JN757_RS08155	COG0697	spore germination
JN757_RS08165	COG0583	DNA-binding transcription factor activity
JN757_RS08170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JN757_RS08205	COG2274	protein secretion by the type I secretion system
JN757_RS08230	COG2832	Protein of unknown function (DUF454)
JN757_RS08255	COG1752	Esterase of the alpha-beta hydrolase superfamily
JN757_RS08270	COG2207	Transcriptional regulator
JN757_RS08295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JN757_RS08300	COG0778	Nitroreductase
JN757_RS08305	COG0642	Histidine kinase
JN757_RS08315	COG0745	RESPONSE REGULATOR receiver
JN757_RS08325	COG2350	Protein conserved in bacteria
JN757_RS08330	COG2917	probably involved in intracellular septation
JN757_RS08335	COG0613	PHP domain protein
JN757_RS08340	COG0009	L-threonylcarbamoyladenylate synthase
JN757_RS08345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JN757_RS08350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JN757_RS08375	COG1113	amino acid transport
JN757_RS08400	COG2154	pterin-4-alpha-carbinolamine dehydratase
JN757_RS08415	COG4787	bacterial-type flagellum-dependent cell motility
JN757_RS08425	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JN757_RS08430	COG1706	bacterial-type flagellum-dependent cell motility
JN757_RS08440	COG1256	bacterial-type flagellum assembly
JN757_RS08450	COG0438	transferase activity, transferring glycosyl groups
JN757_RS08450	COG1216	Glycosyl transferase, family 2
JN757_RS08460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JN757_RS08470	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JN757_RS08480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN757_RS08495	COG0438	transferase activity, transferring glycosyl groups
JN757_RS08495	COG1216	Glycosyl transferase, family 2
JN757_RS08500	COG1086	Polysaccharide biosynthesis protein
JN757_RS08505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JN757_RS08515	COG1083	cytidylyl-transferase
JN757_RS08525	COG2089	acid synthase
JN757_RS08530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JN757_RS08545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JN757_RS08585	COG1677	Flagellar hook-basal body complex protein FliE
JN757_RS08600	COG1317	bacterial-type flagellum organization
JN757_RS08620	COG0745	RESPONSE REGULATOR receiver
JN757_RS08635	COG1580	Controls the rotational direction of flagella during chemotaxis
JN757_RS08660	COG1987	bacterial-type flagellum assembly
JN757_RS08720	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JN757_RS08725	COG0643	Histidine kinase
JN757_RS08725	COG2198	Histidine kinase
JN757_RS08725	COG0784	Response regulator, receiver
JN757_RS08730	COG2201	protein-glutamate methylesterase activity
JN757_RS08735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JN757_RS08745	COG1192	Involved in chromosome partitioning
JN757_RS08755	COG0835	chemotaxis
JN757_RS08780	COG4133	protoheme IX ABC transporter activity
JN757_RS08800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JN757_RS08805	COG1138	Cytochrome C-type biogenesis protein
JN757_RS08815	COG3088	subunit of a heme lyase
JN757_RS08830	COG2814	Major facilitator Superfamily
JN757_RS08840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN757_RS08845	COG4413	Urea transporter
JN757_RS08850	COG0469	pyruvate kinase activity
JN757_RS08860	COG2084	Dehydrogenase
JN757_RS08865	COG3622	Belongs to the hyi family
JN757_RS08870	COG3960	tartronate-semialdehyde synthase activity
JN757_RS08885	COG1309	transcriptional regulator
JN757_RS08890	COG2354	Protein conserved in bacteria
JN757_RS08895	COG2853	Lipoprotein
JN757_RS08915	COG2113	Glycine betaine
JN757_RS08920	COG3162	membrane
JN757_RS08925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JN757_RS08935	COG2009	succinate dehydrogenase
JN757_RS08940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JN757_RS08945	COG1053	succinate dehydrogenase
JN757_RS08950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JN757_RS08965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN757_RS08970	COG0045	succinate-CoA ligase (ADP-forming) activity
JN757_RS09010	COG0326	Molecular chaperone. Has ATPase activity
JN757_RS09020	COG1741	Belongs to the pirin family
JN757_RS09045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JN757_RS09050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JN757_RS09060	COG0628	permease
JN757_RS09065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JN757_RS09070	COG0791	NLP P60 protein
JN757_RS09075	COG0791	NLP P60 protein
JN757_RS09095	COG1797	cobyrinic acid a,c-diamide synthase activity
JN757_RS09100	COG0778	Nitroreductase
JN757_RS09105	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JN757_RS09115	COG1492	cobalamin metabolic process
JN757_RS09125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JN757_RS09135	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JN757_RS09185	COG2205	protein histidine kinase activity
JN757_RS09215	COG2076	Multidrug Resistance protein
JN757_RS09220	COG0385	Bile acid
JN757_RS09225	COG2974	May be involved in recombination
JN757_RS09250	COG0753	catalase activity
JN757_RS09255	COG2010	Cytochrome c
JN757_RS09260	COG0545	Peptidyl-prolyl cis-trans isomerase
JN757_RS09285	COG3209	COG3209 Rhs family protein
JN757_RS09285	COG3209	COG3209 Rhs family protein
JN757_RS09295	COG2200	EAL domain
JN757_RS09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JN757_RS09305	COG4221	oxidoreductase activity
JN757_RS09305	COG0604	alcohol dehydrogenase
JN757_RS09305	COG3321	synthase
JN757_RS09310	COG0560	Phosphoserine phosphatase
JN757_RS09315	COG3842	ATPase activity
JN757_RS09325	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN757_RS09345	COG1473	amidohydrolase
JN757_RS09350	COG0668	transmembrane transport
JN757_RS09360	COG1362	aminopeptidase activity
JN757_RS09365	COG0564	pseudouridine synthase activity
JN757_RS09370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JN757_RS09375	COG2894	cell division
JN757_RS09380	COG0850	regulation of cytokinetic process
JN757_RS09385	COG1560	Kdo2-lipid A biosynthetic process
JN757_RS09405	COG2233	PERMEase
JN757_RS09415	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JN757_RS09420	COG4266	Belongs to the allantoicase family
JN757_RS09465	COG2252	PERMEase
JN757_RS09475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN757_RS09485	COG0302	gtp cyclohydrolase
JN757_RS09490	COG2840	Smr protein MutS2
JN757_RS09515	COG1073	alpha beta
JN757_RS09520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JN757_RS09530	COG0235	Class ii aldolase
JN757_RS09535	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JN757_RS09540	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
JN757_RS09550	COG0318	PFAM AMP-dependent synthetase and ligase
JN757_RS09570	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JN757_RS09585	COG2308	Evidence 4 Homologs of previously reported genes of
JN757_RS09595	COG1305	Transglutaminase-like
JN757_RS09610	COG0183	Belongs to the thiolase family
JN757_RS09615	COG1024	Enoyl-CoA hydratase
JN757_RS09615	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN757_RS09620	COG0519	Catalyzes the synthesis of GMP from XMP
JN757_RS09620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JN757_RS09625	COG0598	Magnesium transport protein CorA
JN757_RS09660	COG0393	Putative heavy-metal-binding
JN757_RS09695	COG3209	COG3209 Rhs family protein
JN757_RS09695	COG3209	COG3209 Rhs family protein
JN757_RS09700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN757_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS09710	COG0583	DNA-binding transcription factor activity
JN757_RS09720	COG1953	Uracil, thiamine, allantoin
JN757_RS09730	COG0560	Phosphoserine phosphatase
JN757_RS09740	COG0189	ligase activity
JN757_RS09750	COG4067	protein conserved in archaea
JN757_RS09750	COG0189	ligase activity
JN757_RS09755	COG1802	Transcriptional regulator
JN757_RS09765	COG0372	Belongs to the citrate synthase family
JN757_RS09785	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JN757_RS09800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JN757_RS09815	COG0668	transmembrane transport
JN757_RS09830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JN757_RS09835	COG0243	molybdopterin cofactor binding
JN757_RS09840	COG2146	nitrite reductase [NAD(P)H] activity
JN757_RS09845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JN757_RS09855	COG2223	nitrite transmembrane transporter activity
JN757_RS09860	COG3707	response regulator
JN757_RS09865	COG1116	anion transmembrane transporter activity
JN757_RS09865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN757_RS09870	COG0167	dihydroorotate dehydrogenase activity
JN757_RS09875	COG3130	regulation of translation
JN757_RS09880	COG0116	Belongs to the methyltransferase superfamily
JN757_RS09880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JN757_RS09890	COG2027	D-alanyl-D-alanine carboxypeptidase
JN757_RS09895	COG3171	Protein conserved in bacteria
JN757_RS09900	COG3135	benzoate transporter
JN757_RS09905	COG1802	Transcriptional regulator
JN757_RS09910	COG0402	S-adenosylhomocysteine deaminase activity
JN757_RS09940	COG3115	cell septum assembly
JN757_RS09945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JN757_RS09965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JN757_RS09970	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JN757_RS09975	COG2130	NADP-dependent
JN757_RS09980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JN757_RS09985	COG1960	acyl-CoA dehydrogenase activity
JN757_RS09990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JN757_RS09995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JN757_RS10020	COG2217	Heavy metal translocating P-type atpase
JN757_RS10030	COG0348	domain, Protein
JN757_RS10040	COG2010	Cytochrome c
JN757_RS10055	COG3278	Belongs to the heme-copper respiratory oxidase family
JN757_RS10060	COG2010	Cytochrome c
JN757_RS10075	COG3278	Belongs to the heme-copper respiratory oxidase family
JN757_RS10110	COG0840	transmembrane signaling receptor activity
JN757_RS10125	COG4977	sequence-specific DNA binding
JN757_RS10140	COG3387	PFAM Glycoside hydrolase 15-related
JN757_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS10150	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JN757_RS10165	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JN757_RS10180	COG0657	acetylesterase activity
JN757_RS10185	COG4774	siderophore transport
JN757_RS10215	COG1538	Outer membrane efflux protein
JN757_RS10220	COG1136	(ABC) transporter
JN757_RS10220	COG0577	efflux transmembrane transporter activity
JN757_RS10225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS10240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JN757_RS10255	COG2197	response regulator
JN757_RS10280	COG0708	Exodeoxyribonuclease III
JN757_RS10295	COG2233	PERMEase
JN757_RS10320	COG0556	nucleotide-excision repair
JN757_RS10325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN757_RS10355	COG0596	Alpha beta hydrolase
JN757_RS10365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JN757_RS10385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JN757_RS10390	COG0066	3-isopropylmalate dehydratase activity
JN757_RS10395	COG2226	methyltransferase
JN757_RS10400	COG0473	3-isopropylmalate dehydrogenase activity
JN757_RS10425	COG0135	phosphoribosylanthranilate isomerase activity
JN757_RS10430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JN757_RS10435	COG0285	dihydrofolate synthase activity
JN757_RS10445	COG1286	toxin biosynthetic process
JN757_RS10490	COG2010	Cytochrome c
JN757_RS10490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN757_RS10495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JN757_RS10495	COG3608	succinylglutamate desuccinylase aspartoacylase
JN757_RS10500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS10515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JN757_RS10550	COG1879	ABC-type sugar transport system periplasmic component
JN757_RS10555	COG1129	ABC transporter
JN757_RS10560	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN757_RS10565	COG1609	Transcriptional regulator
JN757_RS10570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN757_RS10575	COG1869	D-ribose catabolic process
JN757_RS10600	COG1278	Cold shock
JN757_RS10610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JN757_RS10615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JN757_RS10620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JN757_RS10625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JN757_RS10630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JN757_RS10635	COG0072	phenylalanine-tRNA ligase activity
JN757_RS10640	COG0776	regulation of translation
JN757_RS10745	COG0604	alcohol dehydrogenase
JN757_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS10745	COG3321	synthase
JN757_RS10755	COG0583	DNA-binding transcription factor activity
JN757_RS10765	COG1741	Belongs to the pirin family
JN757_RS10790	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JN757_RS10815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JN757_RS10820	COG1335	isochorismatase
JN757_RS10835	COG0583	DNA-binding transcription factor activity
JN757_RS10850	COG0500	methyltransferase
JN757_RS10860	COG3657	addiction module killer protein
JN757_RS10890	COG0726	polysaccharide deacetylase
JN757_RS10900	COG1216	Glycosyl transferase, family 2
JN757_RS10910	COG0438	transferase activity, transferring glycosyl groups
JN757_RS10990	COG5383	Protein conserved in bacteria
JN757_RS10995	COG0247	lactate metabolic process
JN757_RS11000	COG0277	FAD linked oxidase domain protein
JN757_RS11005	COG0277	FAD linked oxidase domain protein
JN757_RS11010	COG2267	carboxylic ester hydrolase activity
JN757_RS11015	COG2072	flavoprotein involved in K transport
JN757_RS11020	COG3706	GGDEF domain
JN757_RS11030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN757_RS11045	COG0531	amino acid
JN757_RS11060	COG1335	isochorismatase
JN757_RS11090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JN757_RS11095	COG0583	DNA-binding transcription factor activity
JN757_RS11100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JN757_RS11105	COG4106	trans-aconitate 2-methyltransferase activity
JN757_RS11110	COG3220	belongs to the UPF0276 family
JN757_RS11205	COG0579	oxidoreductase
JN757_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS11255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN757_RS11285	COG0814	amino acid
JN757_RS11300	COG0589	response to stress
JN757_RS11310	COG0745	RESPONSE REGULATOR receiver
JN757_RS11315	COG2205	protein histidine kinase activity
JN757_RS11320	COG3791	Glutathione-dependent formaldehyde-activating
JN757_RS11325	COG2066	Belongs to the glutaminase family
JN757_RS11330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JN757_RS11335	COG0288	reversible hydration of carbon dioxide
JN757_RS11340	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
JN757_RS11345	COG0583	DNA-binding transcription factor activity
JN757_RS11355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JN757_RS11380	COG0640	Transcriptional regulator
JN757_RS11385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JN757_RS11390	COG0431	NADPH-dependent FMN reductase
JN757_RS11400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN757_RS11450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JN757_RS11455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN757_RS11465	COG0022	dehydrogenase e1 component
JN757_RS11470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JN757_RS11475	COG1522	sequence-specific DNA binding
JN757_RS11485	COG0640	Transcriptional regulator
JN757_RS11495	COG0730	response to heat
JN757_RS11520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN757_RS11540	COG1309	transcriptional regulator
JN757_RS11560	COG1953	Uracil, thiamine, allantoin
JN757_RS11575	COG1073	alpha beta
JN757_RS11580	COG0667	Aldo Keto reductase
JN757_RS11585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN757_RS11590	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JN757_RS11595	COG2080	2 iron, 2 sulfur cluster binding
JN757_RS11600	COG1620	l-lactate permease
JN757_RS11625	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JN757_RS11635	COG1177	transmembrane transport
JN757_RS11640	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN757_RS11645	COG3842	ATPase activity
JN757_RS11650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JN757_RS11655	COG0174	glutamine synthetase
JN757_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS11665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS11670	COG1917	Cupin 2, conserved barrel domain protein
JN757_RS11670	COG1396	sequence-specific DNA binding
JN757_RS11680	COG1122	ATPase activity
JN757_RS11720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JN757_RS11745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS11750	COG0174	glutamine synthetase
JN757_RS11760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JN757_RS11800	COG2259	Doxx family
JN757_RS11815	COG0346	lactoylglutathione lyase activity
JN757_RS11825	COG0579	oxidoreductase
JN757_RS11835	COG4251	negative regulation of phosphorylation
JN757_RS11855	COG0640	Transcriptional regulator
JN757_RS11895	COG2203	Gaf domain
JN757_RS11895	COG2199	diguanylate cyclase activity
JN757_RS11910	COG4172	Belongs to the ABC transporter superfamily
JN757_RS11915	COG4239	(ABC) transporter, permease
JN757_RS11920	COG4174	ABC transporter (Permease)
JN757_RS11925	COG4166	transmembrane transport
JN757_RS11930	COG4166	transmembrane transport
JN757_RS11935	COG1388	LysM domain
JN757_RS11935	COG0741	lytic transglycosylase activity
JN757_RS11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN757_RS11950	COG0328	RNA-DNA hybrid ribonuclease activity
JN757_RS11955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JN757_RS11975	COG0431	NADPH-dependent FMN reductase
JN757_RS11990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JN757_RS11995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JN757_RS12000	COG0705	Rhomboid family
JN757_RS12005	COG3139	Protein of unknown function (DUF1315)
JN757_RS12015	COG0308	aminopeptidase N
JN757_RS12020	COG3842	ATPase activity
JN757_RS12030	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN757_RS12040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN757_RS12055	COG2186	Transcriptional regulator
JN757_RS12060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN757_RS12070	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS12075	COG2267	carboxylic ester hydrolase activity
JN757_RS12095	COG1609	Transcriptional regulator
JN757_RS12115	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS12125	COG2706	6-phosphogluconolactonase activity
JN757_RS12145	COG0625	glutathione transferase activity
JN757_RS12155	COG0420	3'-5' exonuclease activity
JN757_RS12195	COG0714	Associated with various cellular activities
JN757_RS12235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN757_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS12335	COG1595	DNA-templated transcription, initiation
JN757_RS12340	COG3712	iron ion homeostasis
JN757_RS12345	COG4774	siderophore transport
JN757_RS12355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JN757_RS12360	COG1301	dicarboxylic acid transport
JN757_RS12365	COG4948	Mandelate Racemase Muconate Lactonizing
JN757_RS12370	COG0583	DNA-binding transcription factor activity
JN757_RS12395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JN757_RS12445	COG5002	protein histidine kinase activity
JN757_RS12450	COG0625	glutathione transferase activity
JN757_RS12470	COG0028	Belongs to the TPP enzyme family
JN757_RS12495	COG3639	organic phosphonate transmembrane transporter activity
JN757_RS12500	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JN757_RS12505	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
JN757_RS12510	COG0251	oxidation-reduction process
JN757_RS12550	COG0826	peptidase U32
JN757_RS12565	COG0583	DNA-binding transcription factor activity
JN757_RS12585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN757_RS12605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JN757_RS12615	COG3546	catalase activity
JN757_RS12620	COG3685	Protein conserved in bacteria
JN757_RS12625	COG1234	tRNA 3'-trailer cleavage
JN757_RS12650	COG1132	(ABC) transporter
JN757_RS12655	COG4566	intracellular signal transduction
JN757_RS12660	COG4566	intracellular signal transduction
JN757_RS12665	COG4191	Histidine kinase
JN757_RS12675	COG1902	pentaerythritol trinitrate reductase activity
JN757_RS12680	COG2010	Cytochrome c
JN757_RS12680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN757_RS12685	COG2080	2 iron, 2 sulfur cluster binding
JN757_RS12690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JN757_RS12690	COG2010	Cytochrome c
JN757_RS12695	COG2814	Major facilitator Superfamily
JN757_RS12720	COG0109	protoheme IX farnesyltransferase activity
JN757_RS12725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JN757_RS12730	COG1845	cytochrome c oxidase, subunit III
JN757_RS12740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN757_RS12760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JN757_RS12790	COG2201	protein-glutamate methylesterase activity
JN757_RS12800	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS12810	COG0366	Alpha amylase catalytic
JN757_RS12825	COG4214	carbohydrate transport
JN757_RS12830	COG1129	ABC transporter
JN757_RS12835	COG4213	ABC transporter substrate-binding protein
JN757_RS12840	COG2115	Belongs to the xylose isomerase family
JN757_RS12845	COG1609	Transcriptional regulator
JN757_RS12845	COG2207	Transcriptional regulator
JN757_RS12855	COG0583	DNA-binding transcription factor activity
JN757_RS12860	COG1960	acyl-CoA dehydrogenase activity
JN757_RS12865	COG1454	alcohol dehydrogenase
JN757_RS12925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS12960	COG4566	intracellular signal transduction
JN757_RS12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN757_RS12980	COG4566	intracellular signal transduction
JN757_RS12995	COG4191	Histidine kinase
JN757_RS13000	COG4566	intracellular signal transduction
JN757_RS13020	COG0477	Major facilitator Superfamily
JN757_RS13025	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS13040	COG0745	RESPONSE REGULATOR receiver
JN757_RS13045	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JN757_RS13110	COG1522	sequence-specific DNA binding
JN757_RS13115	COG0697	spore germination
JN757_RS13125	COG1566	PFAM secretion protein HlyD family protein
JN757_RS13165	COG0811	peptide transport
JN757_RS13195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN757_RS13210	COG1794	racemase activity, acting on amino acids and derivatives
JN757_RS13225	COG3278	Belongs to the heme-copper respiratory oxidase family
JN757_RS13235	COG0484	heat shock protein binding
JN757_RS13245	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JN757_RS13260	COG0587	DNA-directed DNA polymerase activity
JN757_RS13285	COG0784	Response regulator, receiver
JN757_RS13285	COG4191	Histidine kinase
JN757_RS13350	COG0616	signal peptide processing
JN757_RS13395	COG0316	Belongs to the HesB IscA family
JN757_RS13395	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JN757_RS13440	COG1253	flavin adenine dinucleotide binding
JN757_RS13445	COG3706	GGDEF domain
JN757_RS13465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS13470	COG0765	amino acid transport
JN757_RS13475	COG0765	amino acid transport
JN757_RS13500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN757_RS13505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN757_RS13520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN757_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS13530	COG2610	gluconate transmembrane transporter activity
JN757_RS13540	COG4172	Belongs to the ABC transporter superfamily
JN757_RS13545	COG4239	(ABC) transporter, permease
JN757_RS13550	COG4174	ABC transporter (Permease)
JN757_RS13555	COG4166	transmembrane transport
JN757_RS13560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN757_RS13565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JN757_RS13575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JN757_RS13585	COG2197	response regulator
JN757_RS13590	COG0322	excinuclease ABC activity
JN757_RS13635	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JN757_RS13655	COG0604	alcohol dehydrogenase
JN757_RS13660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JN757_RS13660	COG2169	Transcriptional regulator
JN757_RS13665	COG3145	DNA-N1-methyladenine dioxygenase activity
JN757_RS13725	COG3634	alkyl hydroperoxide reductase activity
JN757_RS13745	COG2200	EAL domain
JN757_RS13750	COG0583	DNA-binding transcription factor activity
JN757_RS13755	COG0697	spore germination
JN757_RS13770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN757_RS13770	COG2755	lipolytic protein G-D-S-L family
JN757_RS13775	COG0667	Aldo Keto reductase
JN757_RS13780	COG2271	Major facilitator Superfamily
JN757_RS13785	COG3835	regulator
JN757_RS13790	COG1929	Belongs to the glycerate kinase type-1 family
JN757_RS13815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN757_RS13825	COG1609	Transcriptional regulator
JN757_RS13845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN757_RS13850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS13855	COG0745	RESPONSE REGULATOR receiver
JN757_RS13860	COG2205	protein histidine kinase activity
JN757_RS13865	COG1335	isochorismatase
JN757_RS13875	COG1595	DNA-templated transcription, initiation
JN757_RS13900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JN757_RS13910	COG4574	serine-type endopeptidase inhibitor activity
JN757_RS13965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JN757_RS13970	COG1070	Carbohydrate kinase
JN757_RS13975	COG0246	Mannitol dehydrogenase
JN757_RS13985	COG0395	ABC-type sugar transport system, permease component
JN757_RS13990	COG1175	transmembrane transport
JN757_RS14025	COG4999	Histidine kinase
JN757_RS14025	COG3850	Histidine kinase
JN757_RS14025	COG3437	response regulator, receiver
JN757_RS14025	COG2205	protein histidine kinase activity
JN757_RS14030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JN757_RS14040	COG2205	protein histidine kinase activity
JN757_RS14040	COG0784	Response regulator, receiver
JN757_RS14040	COG5002	protein histidine kinase activity
JN757_RS14055	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JN757_RS14075	COG1566	PFAM secretion protein HlyD family protein
JN757_RS14080	COG2067	long-chain fatty acid transport protein
JN757_RS14085	COG0628	permease
JN757_RS14090	COG0668	transmembrane transport
JN757_RS14120	COG3781	membrane
JN757_RS14135	COG3284	Transcriptional regulator
JN757_RS14155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JN757_RS14160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JN757_RS14165	COG0657	acetylesterase activity
JN757_RS14170	COG3958	Transketolase
JN757_RS14175	COG3959	Transketolase, thiamine diphosphate binding domain
JN757_RS14180	COG2271	Major facilitator Superfamily
JN757_RS14185	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS14190	COG0583	DNA-binding transcription factor activity
JN757_RS14195	COG2851	Citrate transporter
JN757_RS14210	COG0583	DNA-binding transcription factor activity
JN757_RS14220	COG0659	secondary active sulfate transmembrane transporter activity
JN757_RS14245	COG2135	peptidase activity
JN757_RS14345	COG2378	regulation of single-species biofilm formation
JN757_RS14350	COG2433	Pfam Transposase IS66
JN757_RS14370	COG0210	DNA helicase
JN757_RS14435	COG2003	Belongs to the UPF0758 family
JN757_RS14550	COG0270	DNA (cytosine-5-)-methyltransferase activity
JN757_RS14555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JN757_RS14595	COG0583	DNA-binding transcription factor activity
JN757_RS14640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JN757_RS14650	COG0840	transmembrane signaling receptor activity
JN757_RS14660	COG1309	transcriptional regulator
JN757_RS14670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS14675	COG0765	amino acid transport
JN757_RS14690	COG2814	Major facilitator Superfamily
JN757_RS14705	COG1024	Enoyl-CoA hydratase
JN757_RS14710	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS14715	COG1022	Amp-dependent synthetase and ligase
JN757_RS14715	COG3320	Male sterility
JN757_RS14730	COG1802	Transcriptional regulator
JN757_RS14800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JN757_RS14805	COG0583	DNA-binding transcription factor activity
JN757_RS14840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JN757_RS14850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JN757_RS14855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN757_RS14885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS14905	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JN757_RS14910	COG2986	histidine ammonia-lyase
JN757_RS14915	COG2188	Transcriptional regulator
JN757_RS14920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN757_RS14925	COG0251	oxidation-reduction process
JN757_RS14985	COG4735	regulation of single-species biofilm formation
JN757_RS15110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JN757_RS15180	COG0489	protein tyrosine kinase activity
JN757_RS15200	COG0438	transferase activity, transferring glycosyl groups
JN757_RS15205	COG0438	transferase activity, transferring glycosyl groups
JN757_RS15215	COG1215	transferase activity, transferring glycosyl groups
JN757_RS15225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN757_RS15245	COG0174	glutamine synthetase
JN757_RS15255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS15260	COG3008	intermembrane lipid transfer
JN757_RS15270	COG4974	Belongs to the 'phage' integrase family
JN757_RS15280	COG2814	Major facilitator Superfamily
JN757_RS15290	COG1024	Enoyl-CoA hydratase
JN757_RS15295	COG1960	acyl-CoA dehydrogenase activity
JN757_RS15300	COG1024	Enoyl-CoA hydratase
JN757_RS15305	COG1960	acyl-CoA dehydrogenase activity
JN757_RS15310	COG0183	Belongs to the thiolase family
JN757_RS15320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN757_RS15325	COG2207	Transcriptional regulator
JN757_RS15330	COG0672	)-iron permease
JN757_RS15335	COG2822	iron ion transport
JN757_RS15345	COG2822	iron ion transport
JN757_RS15350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN757_RS15365	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN757_RS15370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JN757_RS15420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS15435	COG0210	DNA helicase
JN757_RS15450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN757_RS15520	COG2072	flavoprotein involved in K transport
JN757_RS15550	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS15580	COG2207	Transcriptional regulator
JN757_RS15585	COG2211	Major facilitator Superfamily
JN757_RS15595	COG0673	inositol 2-dehydrogenase activity
JN757_RS15600	COG1609	Transcriptional regulator
JN757_RS15605	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS15615	COG0583	DNA-binding transcription factor activity
JN757_RS15625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS15640	COG0154	amidase activity
JN757_RS15660	COG3609	addiction module antidote protein, CC2985 family
JN757_RS15695	COG3276	selenocysteine insertion sequence binding
JN757_RS15700	COG1921	L-seryl-tRNASec selenium transferase activity
JN757_RS15705	COG3058	Necessary for formate dehydrogenase activity
JN757_RS15710	COG2864	formate dehydrogenase
JN757_RS15715	COG0437	4 iron, 4 sulfur cluster binding
JN757_RS15725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JN757_RS15730	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS15765	COG1199	ATP-dependent helicase activity
JN757_RS15765	COG1199	ATP-dependent helicase activity
JN757_RS15790	COG2816	NAD+ diphosphatase activity
JN757_RS15795	COG1024	Enoyl-CoA hydratase
JN757_RS15800	COG2133	pyrroloquinoline quinone binding
JN757_RS15810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JN757_RS15845	COG1132	(ABC) transporter
JN757_RS15865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN757_RS15870	COG0488	(ABC) transporter
JN757_RS15885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JN757_RS15890	COG0583	DNA-binding transcription factor activity
JN757_RS15905	COG1968	undecaprenyl-diphosphatase activity
JN757_RS15910	COG0840	transmembrane signaling receptor activity
JN757_RS15955	COG2204	response regulator
JN757_RS15970	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JN757_RS15975	COG0561	phosphatase activity
JN757_RS15980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JN757_RS15985	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JN757_RS15995	COG2194	sulfuric ester hydrolase activity
JN757_RS16020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JN757_RS16035	COG2233	PERMEase
JN757_RS16085	COG2366	antibiotic biosynthetic process
JN757_RS16120	COG1238	metal cluster binding
JN757_RS16125	COG0596	Alpha beta hydrolase
JN757_RS16130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN757_RS16135	COG0297	glycogen (starch) synthase activity
JN757_RS16140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JN757_RS16180	COG1215	transferase activity, transferring glycosyl groups
JN757_RS16190	COG3568	Endonuclease Exonuclease Phosphatase
JN757_RS16200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JN757_RS16220	COG1285	pathogenesis
JN757_RS16230	COG0348	domain, Protein
JN757_RS16235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN757_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS16265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS16290	COG0714	Associated with various cellular activities
JN757_RS16325	COG3119	arylsulfatase activity
JN757_RS16350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN757_RS16365	COG2081	HI0933 family
JN757_RS16370	COG2188	Transcriptional regulator
JN757_RS16410	COG2199	diguanylate cyclase activity
JN757_RS16425	COG1944	ATP diphosphatase activity
JN757_RS16430	COG5001	Diguanylate cyclase
JN757_RS16430	COG3300	MHYT domain
JN757_RS16440	COG1271	oxidase subunit
JN757_RS16475	COG3706	GGDEF domain
JN757_RS16475	COG2203	Gaf domain
JN757_RS16475	COG4251	negative regulation of phosphorylation
JN757_RS16475	COG5001	Diguanylate cyclase
JN757_RS16485	COG0668	transmembrane transport
JN757_RS16490	COG2365	Tyrosine phosphatase family
JN757_RS16525	COG2358	TRAP transporter, solute receptor (TAXI family
JN757_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS16585	COG0583	DNA-binding transcription factor activity
JN757_RS16590	COG2814	Major facilitator Superfamily
JN757_RS16625	COG1196	nuclear chromosome segregation
JN757_RS16645	COG0604	alcohol dehydrogenase
JN757_RS16650	COG0583	DNA-binding transcription factor activity
JN757_RS16670	COG2080	2 iron, 2 sulfur cluster binding
JN757_RS16685	COG4221	oxidoreductase activity
JN757_RS16695	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS16700	COG2207	Transcriptional regulator
JN757_RS16705	COG2814	Major facilitator Superfamily
JN757_RS16720	COG3011	Protein conserved in bacteria
JN757_RS16750	COG2323	membrane
JN757_RS16760	COG1058	Belongs to the CinA family
JN757_RS16760	COG1546	Belongs to the CinA family
JN757_RS16765	COG1063	alcohol dehydrogenase
JN757_RS16780	COG0500	methyltransferase
JN757_RS16810	COG0583	DNA-binding transcription factor activity
JN757_RS16825	COG3264	Mechanosensitive ion channel
JN757_RS16825	COG1511	domain protein
JN757_RS16835	COG2814	Major facilitator Superfamily
JN757_RS16870	COG1104	cysteine desulfurase activity
JN757_RS16900	COG0531	amino acid
JN757_RS16905	COG3938	Belongs to the proline racemase family
JN757_RS16910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JN757_RS16935	COG1064	alcohol dehydrogenase
JN757_RS16940	COG2384	SAM-dependent methyltransferase
JN757_RS16945	COG1942	4-Oxalocrotonate Tautomerase
JN757_RS16955	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS16995	COG1335	isochorismatase
JN757_RS17020	COG2169	Transcriptional regulator
JN757_RS17030	COG2271	Major facilitator Superfamily
JN757_RS17040	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS17045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN757_RS17055	COG1309	transcriptional regulator
JN757_RS17065	COG1902	pentaerythritol trinitrate reductase activity
JN757_RS17070	COG3046	protein related to deoxyribodipyrimidine photolyase
JN757_RS17080	COG2203	Gaf domain
JN757_RS17080	COG3706	GGDEF domain
JN757_RS17080	COG5001	Diguanylate cyclase
JN757_RS17080	COG4251	negative regulation of phosphorylation
JN757_RS17085	COG2207	Transcriptional regulator
JN757_RS17095	COG1335	isochorismatase
JN757_RS17120	COG1999	signal sequence binding
JN757_RS17145	COG1136	(ABC) transporter
JN757_RS17145	COG0577	efflux transmembrane transporter activity
JN757_RS17150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS17185	COG1368	sulfuric ester hydrolase activity
JN757_RS17190	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JN757_RS17195	COG0024	Methionine aminopeptidase
JN757_RS17205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JN757_RS17210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN757_RS17215	COG1120	ATPase activity
JN757_RS17225	COG0626	cystathionine gamma-synthase activity
JN757_RS17230	COG2205	protein histidine kinase activity
JN757_RS17230	COG0784	Response regulator, receiver
JN757_RS17230	COG2198	Histidine kinase
JN757_RS17235	COG2197	response regulator
JN757_RS17245	COG4774	siderophore transport
JN757_RS17255	COG2301	Belongs to the HpcH HpaI aldolase family
JN757_RS17260	COG0019	diaminopimelate decarboxylase activity
JN757_RS17265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JN757_RS17270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JN757_RS17275	COG4264	IucA IucC family
JN757_RS17280	COG2814	Major facilitator Superfamily
JN757_RS17290	COG1595	DNA-templated transcription, initiation
JN757_RS17295	COG3712	iron ion homeostasis
JN757_RS17310	COG4139	cobalamin transport
JN757_RS17315	COG1120	ATPase activity
JN757_RS17325	COG2207	Transcriptional regulator
JN757_RS17330	COG0861	Integral membrane protein TerC family
JN757_RS17340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JN757_RS17350	COG0840	transmembrane signaling receptor activity
JN757_RS17355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN757_RS17360	COG0463	Glycosyl transferase, family 2
JN757_RS17400	COG0625	glutathione transferase activity
JN757_RS17415	COG0583	DNA-binding transcription factor activity
JN757_RS17420	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS17435	COG2995	paraquat-inducible protein a
JN757_RS17440	COG0247	lactate metabolic process
JN757_RS17440	COG0277	FAD linked oxidase domain protein
JN757_RS17445	COG0583	DNA-binding transcription factor activity
JN757_RS17450	COG4948	Mandelate Racemase Muconate Lactonizing
JN757_RS17460	COG0583	DNA-binding transcription factor activity
JN757_RS17485	COG0494	nUDIX hydrolase
JN757_RS17500	COG2135	peptidase activity
JN757_RS17525	COG1611	Belongs to the LOG family
JN757_RS17545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JN757_RS17545	COG2111	Na H antiporter
JN757_RS17550	COG1006	Multisubunit Na H antiporter MnhC subunit
JN757_RS17555	COG0651	ATP synthesis coupled electron transport
JN757_RS17565	COG2212	antiporter activity
JN757_RS17570	COG1320	monovalent cation:proton antiporter activity
JN757_RS17610	COG0840	transmembrane signaling receptor activity
JN757_RS17630	COG4335	DNA alkylation repair
JN757_RS17665	COG2207	Transcriptional regulator
JN757_RS17710	COG0583	DNA-binding transcription factor activity
JN757_RS17720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS17725	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN757_RS17730	COG3383	formate dehydrogenase (NAD+) activity
JN757_RS17755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN757_RS17765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JN757_RS17790	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JN757_RS17795	COG0534	Mate efflux family protein
JN757_RS17805	COG3706	GGDEF domain
JN757_RS17815	COG3474	cytochrome
JN757_RS17820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN757_RS17825	COG0697	spore germination
JN757_RS17830	COG4977	sequence-specific DNA binding
JN757_RS17840	COG0784	Response regulator, receiver
JN757_RS17840	COG4191	Histidine kinase
JN757_RS17845	COG0659	secondary active sulfate transmembrane transporter activity
JN757_RS17855	COG1335	isochorismatase
JN757_RS17870	COG0494	nUDIX hydrolase
JN757_RS17875	COG3209	COG3209 Rhs family protein
JN757_RS17890	COG0454	-acetyltransferase
JN757_RS17925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JN757_RS17930	COG0435	Glutathione S-transferase
JN757_RS17935	COG1648	precorrin-2 dehydrogenase activity
JN757_RS17935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JN757_RS17940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JN757_RS17945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JN757_RS17950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JN757_RS17955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JN757_RS17960	COG1674	ftsk spoiiie
JN757_RS17965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JN757_RS17970	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JN757_RS17975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JN757_RS17980	COG0542	response to heat
JN757_RS17985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JN757_RS17990	COG1278	Cold shock
JN757_RS18010	COG0482	sulfurtransferase activity
JN757_RS18015	COG2915	High frequency lysogenization protein hflD homolog
JN757_RS18025	COG2850	peptidyl-arginine hydroxylation
JN757_RS18030	COG2153	protein acetylation
JN757_RS18045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN757_RS18050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN757_RS18055	COG0649	NAD binding
JN757_RS18055	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN757_RS18070	COG1034	ATP synthesis coupled electron transport
JN757_RS18075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JN757_RS18080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JN757_RS18090	COG0713	ATP synthesis coupled electron transport
JN757_RS18105	COG1007	ATP synthesis coupled electron transport
JN757_RS18140	COG0395	ABC-type sugar transport system, permease component
JN757_RS18150	COG3842	ATPase activity
JN757_RS18155	COG3842	ATPase activity
JN757_RS18160	COG3284	Transcriptional regulator
JN757_RS18165	COG0215	cysteine-tRNA ligase activity
JN757_RS18170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN757_RS18180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JN757_RS18185	COG2814	Major facilitator Superfamily
JN757_RS18190	COG1566	PFAM secretion protein HlyD family protein
JN757_RS18195	COG1538	Outer membrane efflux protein
JN757_RS18200	COG1846	Transcriptional regulator
JN757_RS18205	COG2911	Protein conserved in bacteria
JN757_RS18210	COG0729	surface antigen
JN757_RS18220	COG0708	Exodeoxyribonuclease III
JN757_RS18225	COG2885	chlorophyll binding
JN757_RS18230	COG1960	acyl-CoA dehydrogenase activity
JN757_RS18240	COG0789	Transcriptional regulator
JN757_RS18250	COG0318	PFAM AMP-dependent synthetase and ligase
JN757_RS18255	COG1960	acyl-CoA dehydrogenase activity
JN757_RS18260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN757_RS18265	COG1024	Enoyl-CoA hydratase
JN757_RS18275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JN757_RS18285	COG2866	Carboxypeptidase
JN757_RS18290	COG3038	cytochrome b561
JN757_RS18325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JN757_RS18335	COG0217	transcriptional regulatory protein
JN757_RS18345	COG0583	DNA-binding transcription factor activity
JN757_RS18350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JN757_RS18355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JN757_RS18370	COG3038	cytochrome b561
JN757_RS18380	COG1902	pentaerythritol trinitrate reductase activity
JN757_RS18380	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN757_RS18405	COG2814	Major facilitator Superfamily
JN757_RS18410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN757_RS18415	COG0776	regulation of translation
JN757_RS18420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JN757_RS18425	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JN757_RS18430	COG0740	serine-type endopeptidase activity
JN757_RS18435	COG0544	peptidyl-prolyl cis-trans isomerase activity
JN757_RS18460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JN757_RS18465	COG1686	Belongs to the peptidase S11 family
JN757_RS18490	COG1253	flavin adenine dinucleotide binding
JN757_RS18500	COG0583	DNA-binding transcription factor activity
JN757_RS18510	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JN757_RS18520	COG3132	Protein of unknown function, DUF480
JN757_RS18530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN757_RS18550	COG0628	permease
JN757_RS18555	COG0826	peptidase U32
JN757_RS18565	COG1609	Transcriptional regulator
JN757_RS18610	COG0730	response to heat
JN757_RS18615	COG2814	Major facilitator Superfamily
JN757_RS18630	COG0656	L-ascorbic acid biosynthetic process
JN757_RS18640	COG0417	DNA replication proofreading
JN757_RS18645	COG0517	IMP dehydrogenase activity
JN757_RS18675	COG4166	transmembrane transport
JN757_RS18680	COG4174	ABC transporter (Permease)
JN757_RS18685	COG4239	(ABC) transporter, permease
JN757_RS18690	COG4172	Belongs to the ABC transporter superfamily
JN757_RS18720	COG0113	porphobilinogen synthase activity
JN757_RS18725	COG0625	glutathione transferase activity
JN757_RS18735	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JN757_RS18825	COG2056	Na+-H+ antiporter family
JN757_RS18830	COG0840	transmembrane signaling receptor activity
JN757_RS18860	COG0720	synthase
JN757_RS18865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JN757_RS18870	COG0402	S-adenosylhomocysteine deaminase activity
JN757_RS18875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JN757_RS18880	COG2223	nitrite transmembrane transporter activity
JN757_RS18885	COG4772	TonB-dependent receptor
JN757_RS18895	COG1595	DNA-templated transcription, initiation
JN757_RS18900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JN757_RS18905	COG1595	DNA-templated transcription, initiation
JN757_RS18910	COG3712	iron ion homeostasis
JN757_RS18925	COG3706	GGDEF domain
JN757_RS18925	COG5001	Diguanylate cyclase
JN757_RS18925	COG2203	Gaf domain
JN757_RS18925	COG4251	negative regulation of phosphorylation
JN757_RS18955	COG2132	Multicopper oxidase
JN757_RS18985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JN757_RS18995	COG1968	undecaprenyl-diphosphatase activity
JN757_RS19010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JN757_RS19015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JN757_RS19040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JN757_RS19085	COG3206	protein involved in exopolysaccharide biosynthesis
JN757_RS19085	COG0489	protein tyrosine kinase activity
JN757_RS19100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JN757_RS19115	COG2853	Lipoprotein
JN757_RS19130	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JN757_RS19130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JN757_RS19150	COG4591	ABC-type transport system involved in lipoprotein release permease component
JN757_RS19155	COG1136	(ABC) transporter
JN757_RS19160	COG4591	ABC-type transport system involved in lipoprotein release permease component
JN757_RS19170	COG0584	glycerophosphoryl diester phosphodiesterase
JN757_RS19175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JN757_RS19180	COG1477	protein flavinylation
JN757_RS19195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JN757_RS19205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JN757_RS19215	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JN757_RS19260	COG0183	Belongs to the thiolase family
JN757_RS19265	COG1024	Enoyl-CoA hydratase
JN757_RS19265	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN757_RS19275	COG0589	response to stress
JN757_RS19280	COG0488	(ABC) transporter
JN757_RS19285	COG0741	lytic transglycosylase activity
JN757_RS19295	COG1132	(ABC) transporter
JN757_RS19305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN757_RS19315	COG0425	Belongs to the sulfur carrier protein TusA family
JN757_RS19320	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JN757_RS19335	COG1397	ADP-ribosylglycohydrolase
JN757_RS19345	COG0768	penicillin binding
JN757_RS19390	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS19410	COG1280	lysine exporter protein (LysE YggA)
JN757_RS19435	COG0596	Alpha beta hydrolase
JN757_RS19440	COG0583	DNA-binding transcription factor activity
JN757_RS19445	COG0066	3-isopropylmalate dehydratase activity
JN757_RS19450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JN757_RS19480	COG1121	(ABC) transporter
JN757_RS19485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JN757_RS19510	COG0642	Histidine kinase
JN757_RS19530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN757_RS19540	COG1073	alpha beta
JN757_RS19565	COG1309	transcriptional regulator
JN757_RS19580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JN757_RS19585	COG1960	acyl-CoA dehydrogenase activity
JN757_RS19590	COG1024	Enoyl-CoA hydratase
JN757_RS19605	COG3123	guanosine phosphorylase activity
JN757_RS19610	COG0633	Ferredoxin
JN757_RS19610	COG3217	Mosc domain protein beta barrel domain protein
JN757_RS19625	COG3851	Histidine kinase
JN757_RS19630	COG2197	response regulator
JN757_RS19635	COG1597	lipid kinase activity
JN757_RS19645	COG0303	'Molybdopterin
JN757_RS19650	COG0521	Mo-molybdopterin cofactor biosynthetic process
JN757_RS19655	COG0746	molybdenum cofactor guanylyltransferase activity
JN757_RS19665	COG0564	pseudouridine synthase activity
JN757_RS19685	COG0004	ammonium transporteR
JN757_RS19705	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JN757_RS19715	COG2197	response regulator
JN757_RS19725	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JN757_RS19725	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JN757_RS19730	COG1956	GAF domain-containing protein
JN757_RS19740	COG2205	protein histidine kinase activity
JN757_RS19740	COG0784	Response regulator, receiver
JN757_RS19740	COG5002	protein histidine kinase activity
JN757_RS19745	COG1846	Transcriptional regulator
JN757_RS19750	COG0386	Belongs to the glutathione peroxidase family
JN757_RS19755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JN757_RS19760	COG0436	Aminotransferase
JN757_RS19765	COG0501	Belongs to the peptidase M48B family
JN757_RS19770	COG0500	methyltransferase
JN757_RS19775	COG3384	dioxygenase
JN757_RS19785	COG1024	Enoyl-CoA hydratase
JN757_RS19795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JN757_RS19800	COG3214	Protein conserved in bacteria
JN757_RS19810	COG0583	DNA-binding transcription factor activity
JN757_RS19820	COG0583	DNA-binding transcription factor activity
JN757_RS19825	COG1846	Transcriptional regulator
JN757_RS19830	COG1764	response to oxidative stress
JN757_RS19840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JN757_RS19855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN757_RS19875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JN757_RS19905	COG1376	ErfK ybiS ycfS ynhG family protein
JN757_RS19920	COG4181	ATPase activity
JN757_RS19925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JN757_RS19940	COG2259	Doxx family
JN757_RS19945	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JN757_RS19990	COG2205	protein histidine kinase activity
JN757_RS19995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JN757_RS20005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JN757_RS20030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN757_RS20035	COG4221	oxidoreductase activity
JN757_RS20040	COG1555	photosystem II stabilization
JN757_RS20060	COG0463	Glycosyl transferase, family 2
JN757_RS20080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JN757_RS20115	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JN757_RS20135	COG0776	regulation of translation
JN757_RS20150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JN757_RS20155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JN757_RS20160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JN757_RS20170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JN757_RS20180	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JN757_RS20185	COG0402	S-adenosylhomocysteine deaminase activity
JN757_RS20190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JN757_RS20195	COG0546	phosphoglycolate phosphatase activity
JN757_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS20215	COG5002	protein histidine kinase activity
JN757_RS20215	COG5001	Diguanylate cyclase
JN757_RS20230	COG1054	Belongs to the UPF0176 family
JN757_RS20235	COG0271	Belongs to the BolA IbaG family
JN757_RS20245	COG0114	fumarate hydratase activity
JN757_RS20250	COG0697	spore germination
JN757_RS20260	COG0183	Belongs to the thiolase family
JN757_RS20265	COG2326	polyphosphate kinase activity
JN757_RS20270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS20270	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JN757_RS20280	COG0367	asparagine synthase
JN757_RS20285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JN757_RS20285	COG0189	ligase activity
JN757_RS20295	COG3089	Belongs to the UPF0270 family
JN757_RS20300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JN757_RS20305	COG1742	UPF0060 membrane protein
JN757_RS20320	COG1368	sulfuric ester hydrolase activity
JN757_RS20340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JN757_RS20345	COG2885	chlorophyll binding
JN757_RS20375	COG2207	Transcriptional regulator
JN757_RS20380	COG1064	alcohol dehydrogenase
JN757_RS20385	COG1414	Transcriptional regulator
JN757_RS20390	COG2271	Major facilitator Superfamily
JN757_RS20395	COG4948	Mandelate Racemase Muconate Lactonizing
JN757_RS20400	COG0800	Aldolase
JN757_RS20405	COG3734	2-keto-3-deoxy-galactonokinase
JN757_RS20415	COG1418	mRNA catabolic process
JN757_RS20435	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JN757_RS20435	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JN757_RS20445	COG1397	ADP-ribosylglycohydrolase
JN757_RS20450	COG2188	Transcriptional regulator
JN757_RS20455	COG1172	Belongs to the binding-protein-dependent transport system permease family
JN757_RS20460	COG1129	ABC transporter
JN757_RS20465	COG1879	ABC-type sugar transport system periplasmic component
JN757_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS20480	COG2186	Transcriptional regulator
JN757_RS20495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JN757_RS20505	COG0084	hydrolase, TatD family'
JN757_RS20520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JN757_RS20525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JN757_RS20535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JN757_RS20540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JN757_RS20555	COG0416	fatty acid biosynthetic process
JN757_RS20560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JN757_RS20570	COG0424	maF-like protein
JN757_RS20575	COG0616	signal peptide processing
JN757_RS20575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JN757_RS20580	COG0546	phosphoglycolate phosphatase activity
JN757_RS20590	COG1530	ribonuclease E activity
JN757_RS20595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JN757_RS20600	COG3608	succinylglutamate desuccinylase aspartoacylase
JN757_RS20600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JN757_RS20615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JN757_RS20620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JN757_RS20625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JN757_RS20630	COG2835	tetraacyldisaccharide 4'-kinase activity
JN757_RS20635	COG1663	tetraacyldisaccharide 4'-kinase activity
JN757_RS20640	COG0848	biopolymer transport protein
JN757_RS20645	COG0811	peptide transport
JN757_RS20660	COG0842	Transport permease protein
JN757_RS20665	COG1131	(ABC) transporter
JN757_RS20670	COG0625	glutathione transferase activity
JN757_RS20680	COG1960	acyl-CoA dehydrogenase activity
JN757_RS20695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JN757_RS20755	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS20760	COG2130	NADP-dependent
JN757_RS20765	COG0284	orotidine-5'-phosphate decarboxylase activity
JN757_RS20780	COG0628	permease
JN757_RS20805	COG1022	Amp-dependent synthetase and ligase
JN757_RS20820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JN757_RS20825	COG4771	TonB-dependent receptor
JN757_RS20835	COG2205	protein histidine kinase activity
JN757_RS20835	COG5002	protein histidine kinase activity
JN757_RS20835	COG0784	Response regulator, receiver
JN757_RS20840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JN757_RS20855	COG3122	Protein conserved in bacteria
JN757_RS20860	COG3956	TIGRFAM MazG family protein
JN757_RS20865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JN757_RS20870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JN757_RS20880	COG4804	nuclease activity
JN757_RS20895	COG5002	protein histidine kinase activity
JN757_RS20895	COG0784	Response regulator, receiver
JN757_RS20895	COG2205	protein histidine kinase activity
JN757_RS20900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN757_RS20920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JN757_RS20925	COG1393	Belongs to the ArsC family
JN757_RS20940	COG2818	Glycosylase
JN757_RS20945	COG0037	tRNA processing
JN757_RS20955	COG3091	SprT-like family
JN757_RS20960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN757_RS20970	COG4977	sequence-specific DNA binding
JN757_RS20970	COG1917	Cupin 2, conserved barrel domain protein
JN757_RS20995	COG2977	Belongs to the P-Pant transferase superfamily
JN757_RS21000	COG2205	protein histidine kinase activity
JN757_RS21005	COG0745	RESPONSE REGULATOR receiver
JN757_RS21020	COG1749	Flagellar hook protein flgE
JN757_RS21035	COG1815	bacterial-type flagellum-dependent cell motility
JN757_RS21040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JN757_RS21045	COG0835	chemotaxis
JN757_RS21045	COG0784	Response regulator, receiver
JN757_RS21055	COG2747	anti-sigma28 factor FlgM
JN757_RS21065	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JN757_RS21070	COG0477	Major facilitator Superfamily
JN757_RS21155	COG2239	Acts as a magnesium transporter
JN757_RS21185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JN757_RS21190	COG0527	aspartate kinase activity
JN757_RS21195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JN757_RS21200	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JN757_RS21205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JN757_RS21210	COG2988	succinylglutamate desuccinylase activity
JN757_RS21220	COG3724	N-succinylarginine dihydrolase activity
JN757_RS21225	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS21240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JN757_RS21280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS21285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JN757_RS21295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JN757_RS21305	COG3727	T/G mismatch-specific endonuclease activity
JN757_RS21345	COG2207	Transcriptional regulator
JN757_RS21380	COG0504	CTP synthase activity
JN757_RS21390	COG0584	glycerophosphoryl diester phosphodiesterase
JN757_RS21410	COG0306	phosphate transporter
JN757_RS21415	COG0583	DNA-binding transcription factor activity
JN757_RS21420	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS21430	COG0583	DNA-binding transcription factor activity
JN757_RS21435	COG4941	Belongs to the sigma-70 factor family
JN757_RS21440	COG3795	YCII-related domain
JN757_RS21450	COG0456	acetyltransferase
JN757_RS21475	COG0436	Aminotransferase
JN757_RS21485	COG3265	gluconokinase activity
JN757_RS21490	COG1609	Transcriptional regulator
JN757_RS21495	COG0583	DNA-binding transcription factor activity
JN757_RS21505	COG2271	Major facilitator Superfamily
JN757_RS21520	COG0242	peptide deformylase activity
JN757_RS21525	COG1295	ribonuclease BN
JN757_RS21530	COG3237	CsbD-like
JN757_RS21540	COG0318	PFAM AMP-dependent synthetase and ligase
JN757_RS21550	COG2267	carboxylic ester hydrolase activity
JN757_RS21555	COG2030	dehydratase
JN757_RS21565	COG3530	Putative quorum-sensing-regulated virulence factor
JN757_RS21580	COG0800	Aldolase
JN757_RS21595	COG1737	Transcriptional regulator
JN757_RS21600	COG0676	glucose-6-phosphate 1-epimerase activity
JN757_RS21610	COG3842	ATPase activity
JN757_RS21615	COG0395	ABC-type sugar transport system, permease component
JN757_RS21620	COG1175	transmembrane transport
JN757_RS21625	COG1653	transport
JN757_RS21665	COG3712	iron ion homeostasis
JN757_RS21680	COG2832	Protein of unknown function (DUF454)
JN757_RS21685	COG0840	transmembrane signaling receptor activity
JN757_RS21690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JN757_RS21710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JN757_RS21735	COG0509	glycine decarboxylation via glycine cleavage system
JN757_RS21740	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JN757_RS21740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JN757_RS21745	COG1760	l-serine dehydratase
JN757_RS21750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN757_RS21755	COG1278	Cold shock
JN757_RS21765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JN757_RS21775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JN757_RS21780	COG0602	queuosine metabolic process
JN757_RS21785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JN757_RS21790	COG2885	chlorophyll binding
JN757_RS21795	COG0823	Involved in the tonB-independent uptake of proteins
JN757_RS21815	COG0824	Thioesterase
JN757_RS21820	COG2255	four-way junction helicase activity
JN757_RS21825	COG0632	four-way junction helicase activity
JN757_RS21830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JN757_RS21835	COG0217	transcriptional regulatory protein
JN757_RS21840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JN757_RS21855	COG0783	Belongs to the Dps family
JN757_RS21865	COG2900	Belongs to the SlyX family
JN757_RS21880	COG0668	transmembrane transport
JN757_RS21885	COG1666	GTP binding
JN757_RS21900	COG2096	Adenosyltransferase
JN757_RS21905	COG0494	nUDIX hydrolase
JN757_RS21915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JN757_RS21920	COG0653	protein targeting
JN757_RS21930	COG0433	COG0433 Predicted ATPase
JN757_RS21940	COG0438	transferase activity, transferring glycosyl groups
JN757_RS21940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JN757_RS21970	COG2925	Exonuclease
JN757_RS21995	COG0714	Associated with various cellular activities
JN757_RS22035	COG0469	pyruvate kinase activity
JN757_RS22040	COG1024	Enoyl-CoA hydratase
JN757_RS22050	COG3706	GGDEF domain
JN757_RS22070	COG4191	Histidine kinase
JN757_RS22080	COG0477	Major facilitator Superfamily
JN757_RS22090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN757_RS22105	COG2207	Transcriptional regulator
JN757_RS22110	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS22120	COG0583	DNA-binding transcription factor activity
JN757_RS22125	COG2910	NAD(P)H-binding
JN757_RS22135	COG0583	DNA-binding transcription factor activity
JN757_RS22170	COG0702	epimerase
JN757_RS22175	COG0583	DNA-binding transcription factor activity
JN757_RS22190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JN757_RS22220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JN757_RS22225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JN757_RS22235	COG3642	lipopolysaccharide core region biosynthetic process
JN757_RS22245	COG0642	Histidine kinase
JN757_RS22260	COG0459	protein refolding
JN757_RS22265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JN757_RS22280	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS22285	COG0489	protein tyrosine kinase activity
JN757_RS22290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN757_RS22290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JN757_RS22300	COG2878	Part of a membrane complex involved in electron transport
JN757_RS22310	COG4659	FMN binding
JN757_RS22315	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JN757_RS22320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JN757_RS22330	COG2197	response regulator
JN757_RS22340	COG0137	argininosuccinate synthase activity
JN757_RS22350	COG0418	dihydroorotase activity
JN757_RS22355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JN757_RS22360	COG0450	alkyl hydroperoxide reductase
JN757_RS22375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JN757_RS22380	COG0243	molybdopterin cofactor binding
JN757_RS22395	COG3842	ATPase activity
JN757_RS22405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JN757_RS22415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JN757_RS22430	COG0583	DNA-binding transcription factor activity
JN757_RS22435	COG0477	Major facilitator Superfamily
JN757_RS22470	COG0814	amino acid
JN757_RS22475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS22480	COG0765	amino acid transport
JN757_RS22485	COG0765	amino acid transport
JN757_RS22490	COG1126	abc transporter atp-binding protein
JN757_RS22510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN757_RS22520	COG0583	DNA-binding transcription factor activity
JN757_RS22530	COG1280	lysine exporter protein (LysE YggA)
JN757_RS22550	COG1858	cytochrome C peroxidase
JN757_RS22555	COG0642	Histidine kinase
JN757_RS22565	COG0531	amino acid
JN757_RS22575	COG2197	response regulator
JN757_RS22580	COG0069	glutamate synthase activity
JN757_RS22585	COG1113	amino acid transport
JN757_RS22630	COG1695	Transcriptional regulator
JN757_RS22635	COG2375	cellular response to nickel ion
JN757_RS22645	COG4628	conserved protein (DUF2132)
JN757_RS22665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JN757_RS22675	COG4106	trans-aconitate 2-methyltransferase activity
JN757_RS22680	COG0500	methyltransferase
JN757_RS22685	COG0590	tRNA wobble adenosine to inosine editing
JN757_RS22705	COG4580	involved in the transport of maltose and maltodextrins
JN757_RS22710	COG0366	Alpha amylase catalytic
JN757_RS22715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JN757_RS22715	COG1263	PTS System
JN757_RS22720	COG2188	Transcriptional regulator
JN757_RS22730	COG0519	Catalyzes the synthesis of GMP from XMP
JN757_RS22730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JN757_RS22750	COG1570	exodeoxyribonuclease VII activity
JN757_RS22755	COG0739	heme binding
JN757_RS22760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JN757_RS22765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN757_RS22770	COG0436	Aminotransferase
JN757_RS22775	COG1160	GTP binding
JN757_RS22790	COG0124	histidyl-tRNA synthetase
JN757_RS22795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JN757_RS22810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JN757_RS22815	COG0105	UTP biosynthetic process
JN757_RS22825	COG0633	Ferredoxin
JN757_RS22830	COG0443	Heat shock 70 kDa protein
JN757_RS22835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JN757_RS22850	COG1104	cysteine desulfurase activity
JN757_RS22875	COG3134	Outer membrane lipoprotein
JN757_RS22890	COG1862	Preprotein translocase
JN757_RS22895	COG0343	queuine tRNA-ribosyltransferase activity
JN757_RS22900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JN757_RS22910	COG0582	viral genome integration into host DNA
JN757_RS22975	COG0758	DNA mediated transformation
JN757_RS23015	COG2161	toxin-antitoxin pair type II binding
JN757_RS23025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JN757_RS23030	COG0583	DNA-binding transcription factor activity
JN757_RS23045	COG0109	protoheme IX farnesyltransferase activity
JN757_RS23055	COG1845	cytochrome c oxidase, subunit III
JN757_RS23060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JN757_RS23065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JN757_RS23070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JN757_RS23075	COG1017	nitric oxide dioxygenase activity
JN757_RS23075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN757_RS23125	COG5002	protein histidine kinase activity
JN757_RS23135	COG3706	GGDEF domain
JN757_RS23135	COG5001	Diguanylate cyclase
JN757_RS23135	COG4251	negative regulation of phosphorylation
JN757_RS23135	COG2203	Gaf domain
JN757_RS23140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JN757_RS23145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JN757_RS23160	COG1181	Belongs to the D-alanine--D-alanine ligase family
JN757_RS23165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JN757_RS23170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JN757_RS23175	COG0772	Belongs to the SEDS family
JN757_RS23180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JN757_RS23185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JN757_RS23190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JN757_RS23195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JN757_RS23210	COG0275	rRNA processing
JN757_RS23215	COG2001	Belongs to the MraZ family
JN757_RS23230	COG3107	peptidoglycan biosynthetic process
JN757_RS23235	COG0792	nuclease activity
JN757_RS23240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JN757_RS23245	COG2823	Periplasmic or secreted lipoprotein
JN757_RS23250	COG2969	positive regulation of protein catabolic process
JN757_RS23255	COG0625	glutathione transferase activity
JN757_RS23260	COG2857	Cytochrome c1
JN757_RS23265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JN757_RS23270	COG0723	plastoquinol--plastocyanin reductase activity
JN757_RS23275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JN757_RS23280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JN757_RS23285	COG0667	Aldo Keto reductase
JN757_RS23290	COG1960	acyl-CoA dehydrogenase activity
JN757_RS23300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JN757_RS23305	COG0180	Tryptophanyl-tRNA synthetase
JN757_RS23325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JN757_RS23350	COG0318	PFAM AMP-dependent synthetase and ligase
JN757_RS23355	COG1280	lysine exporter protein (LysE YggA)
JN757_RS23360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JN757_RS23365	COG2813	Specifically methylates the guanine in position
JN757_RS23370	COG2119	membrane
JN757_RS23375	COG0501	Belongs to the peptidase M48B family
JN757_RS23380	COG0840	transmembrane signaling receptor activity
JN757_RS23385	COG2135	peptidase activity
JN757_RS23440	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JN757_RS23445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JN757_RS23455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JN757_RS23460	COG1090	epimerase
JN757_RS23465	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
JN757_RS23480	COG0789	Transcriptional regulator
JN757_RS23485	COG0415	Belongs to the DNA photolyase family
JN757_RS23495	COG4221	oxidoreductase activity
JN757_RS23500	COG0493	'glutamate synthase
JN757_RS23510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JN757_RS23530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JN757_RS23535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JN757_RS23545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JN757_RS23550	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JN757_RS23560	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JN757_RS23565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JN757_RS23575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JN757_RS23580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JN757_RS23585	COG0193	aminoacyl-tRNA hydrolase activity
JN757_RS23595	COG2223	nitrite transmembrane transporter activity
JN757_RS23635	COG0405	Gamma-glutamyltransferase
JN757_RS23640	COG1280	lysine exporter protein (LysE YggA)
JN757_RS23645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JN757_RS23655	COG0477	Major facilitator Superfamily
JN757_RS23660	COG2031	fatty acid transporter
JN757_RS23675	COG0288	reversible hydration of carbon dioxide
JN757_RS23685	COG0456	acetyltransferase
JN757_RS23710	COG3008	intermembrane lipid transfer
JN757_RS23715	COG2995	paraquat-inducible protein a
JN757_RS23720	COG2995	paraquat-inducible protein a
JN757_RS23750	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
JN757_RS23755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JN757_RS23760	COG1183	phosphatidylcholine synthase activity
JN757_RS23765	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JN757_RS23775	COG0028	Belongs to the TPP enzyme family
JN757_RS23795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JN757_RS23825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JN757_RS23830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JN757_RS23835	COG4558	Periplasmic binding protein
JN757_RS23845	COG1489	DNA binding
JN757_RS23850	COG0436	Aminotransferase
JN757_RS23855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JN757_RS23860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JN757_RS23870	COG4191	Histidine kinase
JN757_RS23890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JN757_RS23895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JN757_RS23905	COG0166	Belongs to the GPI family
JN757_RS23915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JN757_RS23930	COG2823	Periplasmic or secreted lipoprotein
JN757_RS23950	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JN757_RS23955	COG0237	dephospho-CoA kinase activity
JN757_RS23960	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JN757_RS23990	COG1252	NADH dehydrogenase
JN757_RS24025	COG0542	response to heat
JN757_RS24060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JN757_RS24100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JN757_RS24105	COG1047	Peptidyl-prolyl cis-trans
JN757_RS24110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JN757_RS24115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JN757_RS24120	COG0196	riboflavin kinase activity
JN757_RS24130	COG0268	Binds directly to 16S ribosomal RNA
JN757_RS24135	COG2085	NADP oxidoreductase coenzyme F420-dependent
JN757_RS24140	COG1733	regulation of RNA biosynthetic process
JN757_RS24145	COG3045	CreA protein
JN757_RS24150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JN757_RS24155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JN757_RS24160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JN757_RS24165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JN757_RS24170	COG0142	geranyltranstransferase activity
JN757_RS24175	COG2824	Alkylphosphonate utilization operon protein PhnA
JN757_RS24180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JN757_RS24185	COG0545	Peptidyl-prolyl cis-trans isomerase
JN757_RS24195	COG2862	Uncharacterized protein family, UPF0114
JN757_RS24210	COG1067	ATP-dependent peptidase activity
JN757_RS24230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN757_RS24240	COG0488	(ABC) transporter
JN757_RS24250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JN757_RS24270	COG0523	cobalamin synthesis protein
JN757_RS24275	COG2879	small protein
JN757_RS24280	COG1966	Carbon starvation protein
JN757_RS24305	COG1970	mechanosensitive ion channel activity
JN757_RS24320	COG2813	Specifically methylates the guanine in position
JN757_RS24330	COG1294	oxidase, subunit
JN757_RS24335	COG1271	oxidase subunit
JN757_RS24355	COG2252	PERMEase
JN757_RS24360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JN757_RS24365	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JN757_RS24370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JN757_RS24375	COG1309	transcriptional regulator
JN757_RS24380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JN757_RS24380	COG1082	Xylose isomerase domain protein TIM barrel
JN757_RS24385	COG0477	Major facilitator Superfamily
JN757_RS24395	COG2321	neutral zinc metallopeptidase
JN757_RS24410	COG1946	Acyl-CoA thioesterase
JN757_RS24420	COG0123	including yeast histone deacetylase and acetoin utilization protein
JN757_RS24430	COG0513	Belongs to the DEAD box helicase family
JN757_RS24435	COG0697	spore germination
JN757_RS24440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JN757_RS24440	COG1199	ATP-dependent helicase activity
JN757_RS24450	COG3416	Protein conserved in bacteria
JN757_RS24480	COG1643	Atp-dependent helicase
JN757_RS24490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JN757_RS24500	COG1522	sequence-specific DNA binding
JN757_RS24515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JN757_RS24520	COG1960	acyl-CoA dehydrogenase activity
JN757_RS24525	COG2205	protein histidine kinase activity
JN757_RS24525	COG2198	Histidine kinase
JN757_RS24525	COG0784	Response regulator, receiver
JN757_RS24535	COG0352	thiamine-phosphate diphosphorylase activity
JN757_RS24540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JN757_RS24555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JN757_RS24560	COG1702	phosphate starvation-inducible protein PhoH
JN757_RS24565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JN757_RS24570	COG4535	Mg2 and Co2 transporter CorC
JN757_RS24575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JN757_RS24590	COG0495	leucyl-tRNA aminoacylation
JN757_RS24610	COG2951	lytic endotransglycosylase activity
JN757_RS24620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JN757_RS24625	COG0321	lipoyl(octanoyl) transferase activity
JN757_RS24630	COG2921	Belongs to the UPF0250 family
JN757_RS24635	COG1686	Belongs to the peptidase S11 family
JN757_RS24645	COG2951	lytic endotransglycosylase activity
JN757_RS24650	COG0772	Belongs to the SEDS family
JN757_RS24655	COG0768	penicillin binding
JN757_RS24660	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JN757_RS24670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JN757_RS24675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JN757_RS24680	COG2094	Belongs to the DNA glycosylase MPG family
JN757_RS24685	COG0586	Pfam SNARE associated Golgi protein
JN757_RS24720	COG1346	cytolysis
JN757_RS24740	COG0702	epimerase
JN757_RS24755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JN757_RS24760	COG3284	Transcriptional regulator
JN757_RS24770	COG0531	amino acid
JN757_RS24775	COG4303	Ethanolamine ammonia lyase large subunit
JN757_RS24780	COG4302	ethanolamine ammonia-lyase activity
JN757_RS24785	COG0456	acetyltransferase
JN757_RS24790	COG0586	Pfam SNARE associated Golgi protein
JN757_RS24795	COG3228	Belongs to the MtfA family
JN757_RS24800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JN757_RS24815	COG4735	regulation of single-species biofilm formation
JN757_RS24840	COG1715	Restriction endonuclease
JN757_RS24860	COG4676	Protein conserved in bacteria
JN757_RS24865	COG5445	Predicted secreted protein (DUF2300)
JN757_RS24880	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
JN757_RS24885	COG4676	Protein conserved in bacteria
JN757_RS24895	COG1722	exodeoxyribonuclease VII activity
JN757_RS24900	COG0142	geranyltranstransferase activity
JN757_RS24905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JN757_RS24910	COG4206	TonB-dependent receptor
JN757_RS24915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JN757_RS24925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JN757_RS24935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JN757_RS24940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JN757_RS24945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JN757_RS24950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JN757_RS24965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JN757_RS24965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JN757_RS24970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JN757_RS24980	COG2264	protein methyltransferase activity
JN757_RS24985	COG3118	belongs to the thioredoxin family
JN757_RS25015	COG3047	cAMP biosynthetic process
JN757_RS25020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JN757_RS25030	COG1201	RNA secondary structure unwinding
JN757_RS25035	COG0668	transmembrane transport
JN757_RS25045	COG3568	Endonuclease Exonuclease Phosphatase
JN757_RS25050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JN757_RS25055	COG0392	lysyltransferase activity
JN757_RS25070	COG4753	response regulator
JN757_RS25070	COG2207	Transcriptional regulator
JN757_RS25075	COG1335	isochorismatase
JN757_RS25080	COG3789	protein conserved in bacteria
JN757_RS25095	COG3766	membrane
JN757_RS25105	COG0754	glutathionylspermidine amidase activity
JN757_RS25110	COG0629	single-stranded DNA binding
JN757_RS25115	COG2814	Major facilitator Superfamily
JN757_RS25120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JN757_RS25125	COG2193	ferroxidase activity
JN757_RS25135	COG0203	ribosomal protein L17
JN757_RS25140	COG0202	RNA polymerase activity
JN757_RS25145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JN757_RS25150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JN757_RS25155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JN757_RS25160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JN757_RS25170	COG0200	Binds to the 23S rRNA
JN757_RS25175	COG1841	ribosomal large subunit assembly
JN757_RS25180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JN757_RS25185	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JN757_RS25190	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JN757_RS25200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JN757_RS25205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JN757_RS25210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JN757_RS25215	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JN757_RS25220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JN757_RS25225	COG0255	Belongs to the universal ribosomal protein uL29 family
JN757_RS25230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JN757_RS25235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JN757_RS25240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JN757_RS25245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JN757_RS25250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JN757_RS25255	COG0089	rRNA binding
JN757_RS25260	COG0088	Forms part of the polypeptide exit tunnel
JN757_RS25265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JN757_RS25270	COG0051	transcription antitermination factor activity, RNA binding
JN757_RS25275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JN757_RS25280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JN757_RS25285	COG0049	tRNA binding
JN757_RS25290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JN757_RS25295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JN757_RS25300	COG0085	RNA polymerase activity
JN757_RS25305	COG0222	ribosome binding
JN757_RS25310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JN757_RS25315	COG0081	regulation of translation
JN757_RS25320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JN757_RS25340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JN757_RS25365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JN757_RS25400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JN757_RS25405	COG0739	heme binding
JN757_RS25410	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JN757_RS25415	COG0316	Belongs to the HesB IscA family
JN757_RS25420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JN757_RS25425	COG1981	membrane
JN757_RS25440	COG1028	Short-chain dehydrogenase reductase Sdr
JN757_RS25445	COG0537	adenosine 5'-monophosphoramidase activity
JN757_RS25450	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
JN757_RS25455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JN757_RS25460	COG1765	OsmC-like protein
JN757_RS25475	COG0134	indole-3-glycerol-phosphate synthase activity
JN757_RS25480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JN757_RS25485	COG0512	Glutamine amidotransferase of anthranilate synthase
JN757_RS25495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JN757_RS25500	COG0546	phosphoglycolate phosphatase activity
JN757_RS25505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JN757_RS25510	COG1454	alcohol dehydrogenase
JN757_RS25520	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN757_RS25530	COG3842	ATPase activity
JN757_RS25535	COG2197	response regulator
JN757_RS25550	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JN757_RS25555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JN757_RS25560	COG3178	'Phosphotransferase
JN757_RS25565	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JN757_RS25570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JN757_RS25575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JN757_RS25580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JN757_RS25585	COG2967	ApaG domain
JN757_RS25590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JN757_RS25595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JN757_RS25600	COG2766	serine protein kinase
JN757_RS25605	COG2718	Belongs to the UPF0229 family
JN757_RS25610	COG2719	SpoVR family
JN757_RS25615	COG0617	tRNA 3'-terminal CCA addition
JN757_RS25625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JN757_RS25630	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JN757_RS25635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JN757_RS25640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JN757_RS25645	COG0358	DNA primase activity
JN757_RS25650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JN757_RS25680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JN757_RS25685	COG1025	Belongs to the peptidase M16 family
JN757_RS25695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JN757_RS25700	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
JN757_RS25710	COG0535	radical SAM domain protein
JN757_RS25725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JN757_RS25730	COG0583	DNA-binding transcription factor activity
JN757_RS25735	COG1960	acyl-CoA dehydrogenase activity
JN757_RS25740	COG1960	acyl-CoA dehydrogenase activity
JN757_RS25745	COG3706	GGDEF domain
JN757_RS25750	COG1960	acyl-CoA dehydrogenase activity
JN757_RS25770	COG0596	Alpha beta hydrolase
JN757_RS25775	COG0156	8-amino-7-oxononanoate synthase activity
JN757_RS25780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JN757_RS25785	COG1040	competence protein
JN757_RS25790	COG3585	molybdate ion transport
JN757_RS25790	COG2005	Transcriptional regulator
JN757_RS25800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JN757_RS25815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JN757_RS25820	COG2204	response regulator
JN757_RS25830	COG2176	DNA-directed DNA polymerase activity
JN757_RS25835	COG1595	DNA-templated transcription, initiation
JN757_RS25840	COG3712	iron ion homeostasis
JN757_RS25845	COG4774	siderophore transport
JN757_RS25865	COG4452	Inner membrane protein CreD
JN757_RS25870	COG2205	protein histidine kinase activity
JN757_RS25875	COG0745	RESPONSE REGULATOR receiver
JN757_RS25880	COG4067	protein conserved in archaea
JN757_RS25880	COG0189	ligase activity
JN757_RS25885	COG0204	Acyl-transferase
JN757_RS25895	COG1063	alcohol dehydrogenase
JN757_RS25925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JN757_RS25955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JN757_RS25955	COG1017	nitric oxide dioxygenase activity
JN757_RS25960	COG4638	Rieske (2fe-2S)
JN757_RS25970	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JN757_RS25975	COG2181	nitrate reductase activity
JN757_RS25975	COG0247	lactate metabolic process
JN757_RS25980	COG1902	pentaerythritol trinitrate reductase activity
JN757_RS25980	COG0446	pyridine nucleotide-disulphide oxidoreductase
JN757_RS26020	COG3246	L-lysine catabolic process to acetate
JN757_RS26025	COG1250	3-hydroxyacyl-CoA dehydrogenase
JN757_RS26050	COG1760	l-serine dehydratase
JN757_RS26060	COG4176	ABC-type proline glycine betaine transport system permease component
JN757_RS26065	COG3448	diguanylate cyclase activity
JN757_RS26065	COG4175	Glycine betaine
JN757_RS26070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JN757_RS26075	COG1309	transcriptional regulator
JN757_RS26080	COG1012	belongs to the aldehyde dehydrogenase family
JN757_RS26085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JN757_RS26095	COG0312	modulator of DNA gyrase
JN757_RS26100	COG0477	Major facilitator Superfamily
JN757_RS26105	COG0513	Belongs to the DEAD box helicase family
JN757_RS26110	COG2081	HI0933 family
JN757_RS26115	COG1289	transmembrane transporter activity
JN757_RS26125	COG2153	protein acetylation
JN757_RS26135	COG1451	nucleotide metabolic process
JN757_RS26175	COG0126	phosphoglycerate kinase activity
JN757_RS26180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JN757_RS26190	COG0640	Transcriptional regulator
JN757_RS26195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JN757_RS26200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JN757_RS26225	COG2814	Major facilitator Superfamily
JN757_RS26235	COG2116	formate transmembrane transporter activity
JN757_RS26245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JN757_RS26250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JN757_RS26260	COG0513	Belongs to the DEAD box helicase family
JN757_RS26265	COG2353	YceI-like domain
JN757_RS26270	COG3038	cytochrome b561
JN757_RS26290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JN757_RS26295	COG1272	protein, Hemolysin III
JN757_RS26335	COG3052	prosthetic group binding
JN757_RS26340	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
JN757_RS26360	COG0784	Response regulator, receiver
JN757_RS26360	COG2198	Histidine kinase
JN757_RS26360	COG0643	Histidine kinase
JN757_RS26385	COG0189	ligase activity
JN757_RS26395	COG1678	Uncharacterized ACR, COG1678
JN757_RS26400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JN757_RS26405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JN757_RS26410	COG0540	Belongs to the ATCase OTCase family
JN757_RS26415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JN757_RS26430	COG0791	NLP P60 protein
JN757_RS26455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN757_RS26460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JN757_RS26460	COG2813	Specifically methylates the guanine in position
JN757_RS26470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JN757_RS26475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JN757_RS26485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JN757_RS26490	COG2022	thiamine diphosphate biosynthetic process
JN757_RS26500	COG2363	Small membrane protein
JN757_RS26505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JN757_RS26515	COG2177	Part of the ABC transporter FtsEX involved in
JN757_RS26520	COG2884	Cell division ATP-binding protein ftsE
JN757_RS26525	COG0552	protein localization to endoplasmic reticulum
JN757_RS26530	COG0612	Peptidase, M16
JN757_RS26535	COG0612	Peptidase, M16
JN757_RS26540	COG0742	ribosomal rna small subunit methyltransferase
JN757_RS26545	COG0429	hydrolase of the alpha beta-hydrolase fold
JN757_RS26570	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JN757_RS26575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JN757_RS26580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JN757_RS26590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JN757_RS26600	COG0693	protein deglycase activity
JN757_RS26605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JN757_RS26620	COG2814	Major facilitator Superfamily
JN757_RS26625	COG0129	dihydroxy-acid dehydratase activity
JN757_RS26635	COG1823	symporter activity
JN757_RS26650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JN757_RS26665	COG1840	ABC-type Fe3 transport system, periplasmic component
JN757_RS26670	COG1178	ABC-type Fe3 transport system permease component
JN757_RS26675	COG3842	ATPase activity
JN757_RS26680	COG0583	DNA-binding transcription factor activity
JN757_RS26690	COG0789	Transcriptional regulator
JN757_RS26695	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JN757_RS26700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JN757_RS26705	COG0730	response to heat
JN757_RS26720	COG0494	nUDIX hydrolase
JN757_RS26735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JN757_RS26740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JN757_RS26745	COG3204	pilus organization
JN757_RS26750	COG3204	pilus organization
JN757_RS26755	COG0179	Fumarylacetoacetate (FAA) hydrolase
JN757_RS26760	COG0277	FAD linked oxidase domain protein
JN757_RS26765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JN757_RS26775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS26780	COG1683	Conserved Protein
JN757_RS26835	COG1177	transmembrane transport
JN757_RS26840	COG1176	ABC-type spermidine putrescine transport system, permease component I
JN757_RS26845	COG3842	ATPase activity
JN757_RS26865	COG0174	glutamine synthetase
JN757_RS26870	COG0174	glutamine synthetase
JN757_RS26885	COG1116	anion transmembrane transporter activity
JN757_RS26890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JN757_RS26895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JN757_RS26900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JN757_RS26905	COG0431	NADPH-dependent FMN reductase
JN757_RS26910	COG0450	alkyl hydroperoxide reductase
JN757_RS26920	COG4521	taurine ABC transporter
JN757_RS26925	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JN757_RS26925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JN757_RS26940	COG1522	sequence-specific DNA binding
JN757_RS26950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JN757_RS26960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JN757_RS26960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JN757_RS26965	COG0509	glycine decarboxylation via glycine cleavage system
JN757_RS26970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JN757_RS26975	COG1178	ABC-type Fe3 transport system permease component
JN757_RS26985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN757_RS26995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JN757_RS27000	COG0006	proline dipeptidase activity
JN757_RS27005	COG3079	Belongs to the UPF0149 family
JN757_RS27025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JN757_RS27050	COG2271	Major facilitator Superfamily
JN757_RS27065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JN757_RS27085	COG2186	Transcriptional regulator
JN757_RS27090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JN757_RS27095	COG0765	amino acid transport
JN757_RS27100	COG0765	amino acid transport
JN757_RS27105	COG1126	abc transporter atp-binding protein
JN757_RS27110	COG0248	Ppx GppA phosphatase
JN757_RS27115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JN757_RS27125	COG0586	Pfam SNARE associated Golgi protein
JN757_RS27130	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JN757_RS27135	COG1671	Belongs to the UPF0178 family
JN757_RS27140	COG0672	)-iron permease
JN757_RS27170	COG1280	lysine exporter protein (LysE YggA)
JN757_RS27180	COG0488	(ABC) transporter
JN757_RS27205	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JN757_RS27225	COG0181	hydroxymethylbilane synthase activity
JN757_RS27235	COG0165	Argininosuccinate lyase
JN757_RS27240	COG0625	glutathione transferase activity
JN757_RS27260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JN757_RS27270	COG1965	Belongs to the frataxin family
JN757_RS27280	COG0019	diaminopimelate decarboxylase activity
JN757_RS27285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JN757_RS27295	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JN757_RS27300	COG1011	Hydrolase
JN757_RS27310	COG0432	Pfam Uncharacterised protein family UPF0047
JN757_RS27315	COG0004	ammonium transporteR
JN757_RS27320	COG0347	Belongs to the P(II) protein family
JN757_RS27335	COG0606	chelatase, subunit chli
JN757_RS27345	COG0840	transmembrane signaling receptor activity
JN757_RS27350	COG0583	DNA-binding transcription factor activity
JN757_RS27355	COG0534	Mate efflux family protein