locus-tag	class	description
CLM75_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLM75_RS00010	COG0592	DNA-directed DNA polymerase activity
CLM75_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLM75_RS00020	COG0187	DNA topoisomerase II activity
CLM75_RS00025	COG0745	RESPONSE REGULATOR receiver
CLM75_RS00035	COG5002	protein histidine kinase activity
CLM75_RS00045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLM75_RS00050	COG0751	glycine-tRNA ligase activity
CLM75_RS00055	COG0752	glycyl-tRNA synthetase alpha subunit
CLM75_RS00060	COG2818	Glycosylase
CLM75_RS00075	COG0569	domain protein
CLM75_RS00080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLM75_RS00085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLM75_RS00090	COG0242	peptide deformylase activity
CLM75_RS00100	COG0758	DNA mediated transformation
CLM75_RS00105	COG0009	L-threonylcarbamoyladenylate synthase
CLM75_RS00115	COG0408	coproporphyrinogen oxidase activity
CLM75_RS00135	COG3119	arylsulfatase activity
CLM75_RS00140	COG0583	DNA-binding transcription factor activity
CLM75_RS00150	COG3734	2-keto-3-deoxy-galactonokinase
CLM75_RS00155	COG0800	Aldolase
CLM75_RS00160	COG4948	Mandelate Racemase Muconate Lactonizing
CLM75_RS00165	COG2271	Major facilitator Superfamily
CLM75_RS00175	COG0159	tryptophan synthase activity
CLM75_RS00195	COG3360	Dodecin
CLM75_RS00205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS00210	COG1764	response to oxidative stress
CLM75_RS00235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLM75_RS00240	COG0339	signal peptide processing
CLM75_RS00280	COG0659	secondary active sulfate transmembrane transporter activity
CLM75_RS00290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLM75_RS00295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLM75_RS00300	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CLM75_RS00330	COG0109	protoheme IX farnesyltransferase activity
CLM75_RS00345	COG2011	ABC-type metal ion transport system permease component
CLM75_RS00350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLM75_RS00365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLM75_RS00370	COG1121	(ABC) transporter
CLM75_RS00375	COG0735	belongs to the Fur family
CLM75_RS00380	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CLM75_RS00400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLM75_RS00405	COG3245	cytochrome
CLM75_RS00415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLM75_RS00430	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLM75_RS00435	COG5002	protein histidine kinase activity
CLM75_RS00440	COG2204	response regulator
CLM75_RS00450	COG5487	UPF0391 membrane protein
CLM75_RS00460	COG1301	dicarboxylic acid transport
CLM75_RS00465	COG0700	Nucleoside recognition
CLM75_RS00480	COG1127	ABC transporter
CLM75_RS00485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLM75_RS00495	COG0612	Peptidase, M16
CLM75_RS00500	COG1283	sodium-dependent phosphate transmembrane transporter activity
CLM75_RS00505	COG0861	Integral membrane protein TerC family
CLM75_RS00510	COG2851	Citrate transporter
CLM75_RS00545	COG0427	acetyl-CoA hydrolase
CLM75_RS00565	COG0583	DNA-binding transcription factor activity
CLM75_RS00570	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS00575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM75_RS00620	COG3712	iron ion homeostasis
CLM75_RS00625	COG1595	DNA-templated transcription, initiation
CLM75_RS00630	COG0840	transmembrane signaling receptor activity
CLM75_RS00655	COG1802	Transcriptional regulator
CLM75_RS00660	COG2175	clavaminate synthase activity
CLM75_RS00675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM75_RS00700	COG1595	DNA-templated transcription, initiation
CLM75_RS00705	COG3712	iron ion homeostasis
CLM75_RS00710	COG4774	siderophore transport
CLM75_RS00740	COG1289	transmembrane transporter activity
CLM75_RS00750	COG1566	PFAM secretion protein HlyD family protein
CLM75_RS00765	COG5339	Protein conserved in bacteria
CLM75_RS00770	COG0457	Tetratricopeptide repeat
CLM75_RS00775	COG1649	PFAM Uncharacterised BCR, COG1649
CLM75_RS00775	COG0726	polysaccharide deacetylase
CLM75_RS00780	COG1215	transferase activity, transferring glycosyl groups
CLM75_RS00855	COG2304	oxidoreductase activity
CLM75_RS00860	COG1595	DNA-templated transcription, initiation
CLM75_RS00970	COG0582	viral genome integration into host DNA
CLM75_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS00985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLM75_RS00990	COG0745	RESPONSE REGULATOR receiver
CLM75_RS00995	COG2199	diguanylate cyclase activity
CLM75_RS01015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLM75_RS01025	COG4208	sulfate ABC transporter
CLM75_RS01030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CLM75_RS01040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM75_RS01065	COG2807	transmembrane transport
CLM75_RS01070	COG0590	tRNA wobble adenosine to inosine editing
CLM75_RS01075	COG0583	DNA-binding transcription factor activity
CLM75_RS01110	COG0765	amino acid transport
CLM75_RS01115	COG0765	amino acid transport
CLM75_RS01120	COG1126	abc transporter atp-binding protein
CLM75_RS01125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS01145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS01165	COG2011	ABC-type metal ion transport system permease component
CLM75_RS01170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLM75_RS01200	COG1126	abc transporter atp-binding protein
CLM75_RS01205	COG0765	amino acid transport
CLM75_RS01210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS01215	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CLM75_RS01220	COG1045	serine acetyltransferase
CLM75_RS01225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLM75_RS01235	COG0667	Aldo Keto reductase
CLM75_RS01240	COG2175	clavaminate synthase activity
CLM75_RS01245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM75_RS01250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CLM75_RS01255	COG4521	taurine ABC transporter
CLM75_RS01260	COG2918	glutathione biosynthetic process
CLM75_RS01270	COG2183	response to ionizing radiation
CLM75_RS01285	COG0189	ligase activity
CLM75_RS01290	COG4067	protein conserved in archaea
CLM75_RS01290	COG0189	ligase activity
CLM75_RS01295	COG2200	EAL domain
CLM75_RS01300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLM75_RS01310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLM75_RS01315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLM75_RS01330	COG0514	ATP-dependent DNA helicase (RecQ)
CLM75_RS01335	COG0824	Thioesterase
CLM75_RS01345	COG0243	molybdopterin cofactor binding
CLM75_RS01350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLM75_RS01360	COG1652	LysM domain
CLM75_RS01365	COG1011	Hydrolase
CLM75_RS01370	COG0494	nUDIX hydrolase
CLM75_RS01375	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLM75_RS01415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLM75_RS01420	COG2957	Belongs to the agmatine deiminase family
CLM75_RS01440	COG1942	4-Oxalocrotonate Tautomerase
CLM75_RS01445	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS01455	COG2342	PFAM TM1410 hypothetical-related protein
CLM75_RS01480	COG0438	transferase activity, transferring glycosyl groups
CLM75_RS01500	COG1192	Involved in chromosome partitioning
CLM75_RS01505	COG1215	transferase activity, transferring glycosyl groups
CLM75_RS01510	COG1215	transferase activity, transferring glycosyl groups
CLM75_RS01515	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLM75_RS01520	COG0457	Tetratricopeptide repeat
CLM75_RS01545	COG2894	cell division
CLM75_RS01605	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CLM75_RS01610	COG1194	a g-specific adenine glycosylase
CLM75_RS01620	COG2223	nitrite transmembrane transporter activity
CLM75_RS01625	COG0131	Imidazoleglycerol-phosphate dehydratase
CLM75_RS01630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLM75_RS01640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLM75_RS01645	COG0107	imidazoleglycerol-phosphate synthase activity
CLM75_RS01660	COG2861	carbohydrate metabolic process
CLM75_RS01665	COG0793	Belongs to the peptidase S41A family
CLM75_RS01670	COG4942	peptidase
CLM75_RS01675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLM75_RS01680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLM75_RS01690	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CLM75_RS01715	COG3852	Histidine kinase
CLM75_RS01730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLM75_RS01730	COG0301	tRNA thio-modification
CLM75_RS01735	COG1217	gtp-binding protein TYPA
CLM75_RS01745	COG0058	SHG alpha-glucan phosphorylase activity
CLM75_RS01760	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CLM75_RS01775	COG0402	S-adenosylhomocysteine deaminase activity
CLM75_RS01780	COG2188	Transcriptional regulator
CLM75_RS01790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CLM75_RS01795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLM75_RS01805	COG4176	ABC-type proline glycine betaine transport system permease component
CLM75_RS01810	COG4175	Glycine betaine
CLM75_RS01810	COG0517	IMP dehydrogenase activity
CLM75_RS01815	COG2986	histidine ammonia-lyase
CLM75_RS01820	COG2986	histidine ammonia-lyase
CLM75_RS01825	COG1113	amino acid transport
CLM75_RS01830	COG1228	amidohydrolase
CLM75_RS01845	COG0657	acetylesterase activity
CLM75_RS01850	COG0596	Alpha beta hydrolase
CLM75_RS01855	COG1490	D-aminoacyl-tRNA deacylase activity
CLM75_RS01860	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CLM75_RS01865	COG2943	transferase activity, transferring hexosyl groups
CLM75_RS01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS01880	COG0765	amino acid transport
CLM75_RS01885	COG1126	abc transporter atp-binding protein
CLM75_RS01890	COG0840	transmembrane signaling receptor activity
CLM75_RS01895	COG0840	transmembrane signaling receptor activity
CLM75_RS01910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLM75_RS01915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLM75_RS01920	COG0140	phosphoribosyl-ATP diphosphatase activity
CLM75_RS01925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLM75_RS01930	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLM75_RS01940	COG2226	methyltransferase
CLM75_RS01970	COG3188	usher protein
CLM75_RS01975	COG3121	Chaperone
CLM75_RS01980	COG3121	Chaperone
CLM75_RS01995	COG1309	transcriptional regulator
CLM75_RS02020	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLM75_RS02025	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLM75_RS02035	COG0018	arginyl-trna synthetase
CLM75_RS02040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLM75_RS02045	COG0254	rRNA binding
CLM75_RS02055	COG0281	malic enzyme
CLM75_RS02085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLM75_RS02090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLM75_RS02105	COG0070	glutamate synthase
CLM75_RS02105	COG0069	glutamate synthase activity
CLM75_RS02105	COG0067	glutamate synthase
CLM75_RS02110	COG0493	'glutamate synthase
CLM75_RS02120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLM75_RS02125	COG2814	Major facilitator Superfamily
CLM75_RS02130	COG0583	DNA-binding transcription factor activity
CLM75_RS02145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM75_RS02150	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS02160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM75_RS02170	COG2226	methyltransferase
CLM75_RS02195	COG2986	histidine ammonia-lyase
CLM75_RS02210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM75_RS02220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM75_RS02225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM75_RS02240	COG1192	Involved in chromosome partitioning
CLM75_RS02245	COG3118	belongs to the thioredoxin family
CLM75_RS02250	COG4680	protein conserved in bacteria
CLM75_RS02255	COG5499	transcription regulator containing HTH domain
CLM75_RS02260	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CLM75_RS02265	COG3264	Mechanosensitive ion channel
CLM75_RS02265	COG1196	nuclear chromosome segregation
CLM75_RS02270	COG3263	regulation of cellular component size
CLM75_RS02295	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS02305	COG0506	proline dehydrogenase activity
CLM75_RS02305	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLM75_RS02305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLM75_RS02310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLM75_RS02325	COG2873	o-acetylhomoserine
CLM75_RS02330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLM75_RS02335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM75_RS02355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CLM75_RS02360	COG0859	PFAM glycosyl transferase family 9
CLM75_RS02365	COG0859	PFAM glycosyl transferase family 9
CLM75_RS02370	COG0438	transferase activity, transferring glycosyl groups
CLM75_RS02410	COG4772	TonB-dependent receptor
CLM75_RS02420	COG2192	nodulation
CLM75_RS02435	COG0438	transferase activity, transferring glycosyl groups
CLM75_RS02440	COG1215	transferase activity, transferring glycosyl groups
CLM75_RS02450	COG1132	(ABC) transporter
CLM75_RS02455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLM75_RS02455	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CLM75_RS02460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM75_RS02470	COG0667	Aldo Keto reductase
CLM75_RS02490	COG1519	Transferase
CLM75_RS02495	COG1538	Outer membrane efflux protein
CLM75_RS02500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CLM75_RS02515	COG0494	nUDIX hydrolase
CLM75_RS02525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLM75_RS02530	COG3150	esterase
CLM75_RS02560	COG3830	Belongs to the UPF0237 family
CLM75_RS02560	COG0560	Phosphoserine phosphatase
CLM75_RS02565	COG0688	phosphatidylethanolamine metabolic process
CLM75_RS02590	COG1162	GTPase activity
CLM75_RS02595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLM75_RS02600	COG2860	membrane
CLM75_RS02610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLM75_RS02610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLM75_RS02615	COG0802	atpase or kinase
CLM75_RS02620	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLM75_RS02625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLM75_RS02630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLM75_RS02635	COG1923	regulation of RNA biosynthetic process
CLM75_RS02640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLM75_RS02645	COG0330	HflC and HflK could
CLM75_RS02650	COG0330	HflC and HflK could
CLM75_RS02655	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CLM75_RS02660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLM75_RS02670	COG1178	ABC-type Fe3 transport system permease component
CLM75_RS02675	COG1840	ABC-type Fe3 transport system, periplasmic component
CLM75_RS02690	COG0557	exoribonuclease II activity
CLM75_RS02695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLM75_RS02700	COG0360	Binds together with S18 to 16S ribosomal RNA
CLM75_RS02705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLM75_RS02715	COG0359	binds to the 23S rRNA
CLM75_RS02720	COG0305	Participates in initiation and elongation during chromosome replication
CLM75_RS02725	COG1032	radical SAM domain protein
CLM75_RS02750	COG2308	Evidence 4 Homologs of previously reported genes of
CLM75_RS02750	COG2307	Protein conserved in bacteria
CLM75_RS02770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLM75_RS02775	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLM75_RS02780	COG0583	DNA-binding transcription factor activity
CLM75_RS02785	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS02790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS02825	COG4221	oxidoreductase activity
CLM75_RS02845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLM75_RS02850	COG0830	nickel cation binding
CLM75_RS02855	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CLM75_RS02860	COG0791	NLP P60 protein
CLM75_RS02865	COG1309	transcriptional regulator
CLM75_RS02875	COG2982	Protein involved in outer membrane biogenesis
CLM75_RS02885	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLM75_RS02890	COG0697	spore germination
CLM75_RS02920	COG0443	Heat shock 70 kDa protein
CLM75_RS02925	COG0484	heat shock protein binding
CLM75_RS02930	COG0804	urea catabolic process
CLM75_RS02935	COG0832	Belongs to the urease beta subunit family
CLM75_RS02950	COG0831	urea catabolic process
CLM75_RS02955	COG0829	nickel cation binding
CLM75_RS02965	COG0411	ABC transporter
CLM75_RS02990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM75_RS03050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM75_RS03075	COG2095	MarC family integral membrane protein
CLM75_RS03085	COG0151	Belongs to the GarS family
CLM75_RS03090	COG0138	bifunctional purine biosynthesis protein purh
CLM75_RS03100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLM75_RS03110	COG2264	protein methyltransferase activity
CLM75_RS03125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLM75_RS03150	COG0023	Translation Initiation Factor
CLM75_RS03155	COG1166	arginine decarboxylase activity
CLM75_RS03165	COG0534	Mate efflux family protein
CLM75_RS03170	COG2373	Large extracellular alpha-helical protein
CLM75_RS03180	COG4953	penicillin-binding protein 1C
CLM75_RS03190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLM75_RS03260	COG4964	Belongs to the GSP D family
CLM75_RS03295	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS03320	COG2217	Heavy metal translocating P-type atpase
CLM75_RS03335	COG2814	Major facilitator Superfamily
CLM75_RS03345	COG0604	alcohol dehydrogenase
CLM75_RS03350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CLM75_RS03355	COG0583	DNA-binding transcription factor activity
CLM75_RS03365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CLM75_RS03370	COG0387	Pfam Sodium calcium exchanger
CLM75_RS03380	COG4221	oxidoreductase activity
CLM75_RS03385	COG1739	Uncharacterized protein family UPF0029
CLM75_RS03390	COG1309	transcriptional regulator
CLM75_RS03395	COG2233	PERMEase
CLM75_RS03445	COG2995	paraquat-inducible protein a
CLM75_RS03450	COG2995	paraquat-inducible protein a
CLM75_RS03455	COG3008	intermembrane lipid transfer
CLM75_RS03480	COG0456	acetyltransferase
CLM75_RS03490	COG0288	reversible hydration of carbon dioxide
CLM75_RS03510	COG2031	fatty acid transporter
CLM75_RS03515	COG0477	Major facilitator Superfamily
CLM75_RS03570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLM75_RS03595	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLM75_RS03605	COG0405	Gamma-glutamyltransferase
CLM75_RS03660	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLM75_RS03670	COG4794	Type iii secretion
CLM75_RS03695	COG4669	(LipO)protein
CLM75_RS03715	COG0193	aminoacyl-tRNA hydrolase activity
CLM75_RS03720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLM75_RS03725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLM75_RS03735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLM75_RS03740	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CLM75_RS03750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLM75_RS03755	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLM75_RS03765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLM75_RS03770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CLM75_RS03795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM75_RS03805	COG0493	'glutamate synthase
CLM75_RS03810	COG4221	oxidoreductase activity
CLM75_RS03820	COG0415	Belongs to the DNA photolyase family
CLM75_RS03840	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CLM75_RS03845	COG1090	epimerase
CLM75_RS03850	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CLM75_RS03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM75_RS03875	COG0175	sulfate reduction
CLM75_RS03885	COG0204	Acyl-transferase
CLM75_RS03890	COG0280	phosphate acetyltransferase
CLM75_RS03890	COG0857	belongs to the CobB CobQ family
CLM75_RS03910	COG0268	Binds directly to 16S ribosomal RNA
CLM75_RS03920	COG0196	riboflavin kinase activity
CLM75_RS03925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLM75_RS03930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLM75_RS03935	COG1047	Peptidyl-prolyl cis-trans
CLM75_RS03940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLM75_RS03970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS03995	COG0542	response to heat
CLM75_RS04020	COG1252	NADH dehydrogenase
CLM75_RS04050	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CLM75_RS04055	COG0237	dephospho-CoA kinase activity
CLM75_RS04100	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLM75_RS04120	COG0084	hydrolase, TatD family'
CLM75_RS04125	COG1609	Transcriptional regulator
CLM75_RS04135	COG1105	Belongs to the carbohydrate kinase PfkB family
CLM75_RS04140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLM75_RS04140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLM75_RS04140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLM75_RS04150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLM75_RS04155	COG4774	siderophore transport
CLM75_RS04160	COG3128	pkhd-type hydroxylase
CLM75_RS04170	COG0019	diaminopimelate decarboxylase activity
CLM75_RS04195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLM75_RS04210	COG4608	Belongs to the ABC transporter superfamily
CLM75_RS04215	COG0444	Belongs to the ABC transporter superfamily
CLM75_RS04220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM75_RS04225	COG0601	transmembrane transport
CLM75_RS04230	COG0747	negative chemotaxis
CLM75_RS04240	COG0747	negative chemotaxis
CLM75_RS04245	COG0747	negative chemotaxis
CLM75_RS04250	COG0747	negative chemotaxis
CLM75_RS04270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CLM75_RS04275	COG4178	(ABC) transporter
CLM75_RS04290	COG0180	Tryptophanyl-tRNA synthetase
CLM75_RS04295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLM75_RS04305	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS04310	COG0667	Aldo Keto reductase
CLM75_RS04315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLM75_RS04320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLM75_RS04325	COG0723	plastoquinol--plastocyanin reductase activity
CLM75_RS04330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CLM75_RS04335	COG2857	Cytochrome c1
CLM75_RS04340	COG0625	glutathione transferase activity
CLM75_RS04345	COG2969	positive regulation of protein catabolic process
CLM75_RS04350	COG2186	Transcriptional regulator
CLM75_RS04365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM75_RS04375	COG2271	Major facilitator Superfamily
CLM75_RS04380	COG2721	sulfolactate sulfo-lyase activity
CLM75_RS04390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM75_RS04400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLM75_RS04405	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLM75_RS04410	COG0154	amidase activity
CLM75_RS04415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLM75_RS04420	COG1077	Cell shape determining protein MreB Mrl
CLM75_RS04425	COG1792	Involved in formation and maintenance of cell shape
CLM75_RS04435	COG0424	maF-like protein
CLM75_RS04440	COG1530	ribonuclease E activity
CLM75_RS04450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS04455	COG0312	modulator of DNA gyrase
CLM75_RS04460	COG3028	Belongs to the UPF0307 family
CLM75_RS04465	COG0312	modulator of DNA gyrase
CLM75_RS04500	COG1660	Displays ATPase and GTPase activities
CLM75_RS04510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLM75_RS04515	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLM75_RS04520	COG1137	ATPase activity
CLM75_RS04525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CLM75_RS04535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLM75_RS04545	COG1127	ABC transporter
CLM75_RS04550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLM75_RS04555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLM75_RS04575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLM75_RS04580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CLM75_RS04585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLM75_RS04590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM75_RS04600	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLM75_RS04605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CLM75_RS04670	COG2135	peptidase activity
CLM75_RS04675	COG0840	transmembrane signaling receptor activity
CLM75_RS04680	COG0501	Belongs to the peptidase M48B family
CLM75_RS04685	COG2119	membrane
CLM75_RS04690	COG2813	Specifically methylates the guanine in position
CLM75_RS04695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM75_RS04700	COG1280	lysine exporter protein (LysE YggA)
CLM75_RS04705	COG0318	PFAM AMP-dependent synthetase and ligase
CLM75_RS04735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM75_RS04740	COG2885	chlorophyll binding
CLM75_RS04745	COG2823	Periplasmic or secreted lipoprotein
CLM75_RS04750	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLM75_RS04755	COG0792	nuclease activity
CLM75_RS04775	COG2001	Belongs to the MraZ family
CLM75_RS04780	COG0275	rRNA processing
CLM75_RS04795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLM75_RS04800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLM75_RS04805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM75_RS04810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLM75_RS04815	COG0772	Belongs to the SEDS family
CLM75_RS04820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLM75_RS04825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLM75_RS04830	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLM75_RS04845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLM75_RS04850	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CLM75_RS04855	COG2203	Gaf domain
CLM75_RS04855	COG5001	Diguanylate cyclase
CLM75_RS04855	COG4251	negative regulation of phosphorylation
CLM75_RS04855	COG3706	GGDEF domain
CLM75_RS04865	COG5002	protein histidine kinase activity
CLM75_RS04890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS04905	COG0835	chemotaxis
CLM75_RS04905	COG0784	Response regulator, receiver
CLM75_RS04915	COG0583	DNA-binding transcription factor activity
CLM75_RS04940	COG1566	PFAM secretion protein HlyD family protein
CLM75_RS04960	COG0300	oxidoreductase activity
CLM75_RS04975	COG0662	Cupin 2, conserved barrel domain protein
CLM75_RS04975	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CLM75_RS04990	COG1696	Membrane protein involved in D-alanine export
CLM75_RS05005	COG3420	alginic acid biosynthetic process
CLM75_RS05015	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CLM75_RS05020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS05030	COG1215	transferase activity, transferring glycosyl groups
CLM75_RS05040	COG3022	response to hydroperoxide
CLM75_RS05050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CLM75_RS05055	COG0315	cyclic pyranopterin monophosphate synthase activity
CLM75_RS05060	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLM75_RS05070	COG0513	Belongs to the DEAD box helicase family
CLM75_RS05075	COG0400	carboxylic ester hydrolase activity
CLM75_RS05080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS05085	COG4597	amino acid ABC transporter
CLM75_RS05090	COG0765	amino acid transport
CLM75_RS05095	COG1126	abc transporter atp-binding protein
CLM75_RS05110	COG2186	Transcriptional regulator
CLM75_RS05115	COG2807	transmembrane transport
CLM75_RS05120	COG3539	Fimbrial protein
CLM75_RS05125	COG3539	Fimbrial protein
CLM75_RS05130	COG3188	usher protein
CLM75_RS05135	COG3121	Chaperone
CLM75_RS05155	COG3539	Fimbrial protein
CLM75_RS05180	COG2827	Endonuclease containing a URI domain
CLM75_RS05190	COG4774	siderophore transport
CLM75_RS05195	COG2027	D-alanyl-D-alanine carboxypeptidase
CLM75_RS05205	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CLM75_RS05210	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM75_RS05230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CLM75_RS05250	COG0814	amino acid
CLM75_RS05255	COG1760	l-serine dehydratase
CLM75_RS05260	COG0583	DNA-binding transcription factor activity
CLM75_RS05270	COG0477	Major facilitator Superfamily
CLM75_RS05275	COG0583	DNA-binding transcription factor activity
CLM75_RS05280	COG4772	TonB-dependent receptor
CLM75_RS05285	COG3712	iron ion homeostasis
CLM75_RS05290	COG1595	DNA-templated transcription, initiation
CLM75_RS05315	COG3712	iron ion homeostasis
CLM75_RS05325	COG3081	Nucleoid-associated protein
CLM75_RS05335	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CLM75_RS05340	COG0525	valine-tRNA ligase activity
CLM75_RS05355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLM75_RS05360	COG0795	lipopolysaccharide-transporting ATPase activity
CLM75_RS05365	COG0795	lipopolysaccharide-transporting ATPase activity
CLM75_RS05370	COG0481	GTPase activity
CLM75_RS05375	COG0681	Belongs to the peptidase S26 family
CLM75_RS05380	COG0571	ribonuclease III activity
CLM75_RS05385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLM75_RS05390	COG1381	Involved in DNA repair and RecF pathway recombination
CLM75_RS05395	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLM75_RS05405	COG0590	tRNA wobble adenosine to inosine editing
CLM75_RS05410	COG0500	methyltransferase
CLM75_RS05415	COG2226	methyltransferase
CLM75_RS05430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLM75_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS05470	COG0523	cobalamin synthesis protein
CLM75_RS05490	COG4206	TonB-dependent receptor
CLM75_RS05495	COG4628	conserved protein (DUF2132)
CLM75_RS05505	COG2375	cellular response to nickel ion
CLM75_RS05510	COG1695	Transcriptional regulator
CLM75_RS05550	COG1113	amino acid transport
CLM75_RS05570	COG0069	glutamate synthase activity
CLM75_RS05575	COG2197	response regulator
CLM75_RS05585	COG0531	amino acid
CLM75_RS05590	COG0254	rRNA binding
CLM75_RS05610	COG0583	DNA-binding transcription factor activity
CLM75_RS05615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM75_RS05635	COG2076	Multidrug Resistance protein
CLM75_RS05655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLM75_RS05670	COG4191	Histidine kinase
CLM75_RS05675	COG2204	response regulator
CLM75_RS05695	COG1126	abc transporter atp-binding protein
CLM75_RS05700	COG0765	amino acid transport
CLM75_RS05705	COG0765	amino acid transport
CLM75_RS05710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS05725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLM75_RS05735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLM75_RS05740	COG3842	ATPase activity
CLM75_RS05745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLM75_RS05755	COG0243	molybdopterin cofactor binding
CLM75_RS05760	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLM75_RS05775	COG0450	alkyl hydroperoxide reductase
CLM75_RS05780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLM75_RS05785	COG0418	dihydroorotase activity
CLM75_RS05795	COG0137	argininosuccinate synthase activity
CLM75_RS05800	COG2197	response regulator
CLM75_RS05810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLM75_RS05815	COG2878	Part of a membrane complex involved in electron transport
CLM75_RS05820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM75_RS05820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLM75_RS05825	COG0489	protein tyrosine kinase activity
CLM75_RS05830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CLM75_RS05835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLM75_RS05920	COG3179	chitinase
CLM75_RS05930	COG1546	Belongs to the CinA family
CLM75_RS05935	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLM75_RS05940	COG2137	regulation of response to DNA damage stimulus
CLM75_RS05955	COG3148	PFAM DTW domain containing protein
CLM75_RS05970	COG0583	DNA-binding transcription factor activity
CLM75_RS05985	COG4807	Protein conserved in bacteria
CLM75_RS06000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLM75_RS06005	COG3158	transport of potassium into the cell
CLM75_RS06010	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS06020	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CLM75_RS06025	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CLM75_RS06030	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS06035	COG1177	transmembrane transport
CLM75_RS06040	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM75_RS06045	COG3842	ATPase activity
CLM75_RS06050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLM75_RS06060	COG0583	DNA-binding transcription factor activity
CLM75_RS06080	COG0457	Tetratricopeptide repeat
CLM75_RS06080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM75_RS06085	COG0835	chemotaxis
CLM75_RS06095	COG2201	protein-glutamate methylesterase activity
CLM75_RS06100	COG2203	Gaf domain
CLM75_RS06100	COG5001	Diguanylate cyclase
CLM75_RS06100	COG4251	negative regulation of phosphorylation
CLM75_RS06100	COG3706	GGDEF domain
CLM75_RS06115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLM75_RS06135	COG1073	alpha beta
CLM75_RS06150	COG2885	chlorophyll binding
CLM75_RS06165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CLM75_RS06170	COG0563	adenylate kinase activity
CLM75_RS06175	COG1214	PFAM Peptidase M22, glycoprotease
CLM75_RS06185	COG1801	Protein of unknown function DUF72
CLM75_RS06205	COG0742	ribosomal rna small subunit methyltransferase
CLM75_RS06220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS06240	COG2937	Belongs to the GPAT DAPAT family
CLM75_RS06255	COG2226	methyltransferase
CLM75_RS06260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLM75_RS06265	COG1215	transferase activity, transferring glycosyl groups
CLM75_RS06270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLM75_RS06275	COG2166	iron-sulfur cluster assembly
CLM75_RS06280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLM75_RS06285	COG2171	N-acyltransferase activity
CLM75_RS06290	COG1393	Belongs to the ArsC family
CLM75_RS06295	COG0025	NhaP-type Na H and K H
CLM75_RS06310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CLM75_RS06320	COG0052	Belongs to the universal ribosomal protein uS2 family
CLM75_RS06325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLM75_RS06330	COG0528	UMP kinase activity
CLM75_RS06335	COG0233	cytoplasmic translational termination
CLM75_RS06340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLM75_RS06350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CLM75_RS06370	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM75_RS06375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM75_RS06380	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM75_RS06385	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM75_RS06390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLM75_RS06395	COG0587	DNA-directed DNA polymerase activity
CLM75_RS06400	COG0825	malonyl-CoA metabolic process
CLM75_RS06405	COG0037	tRNA processing
CLM75_RS06410	COG0504	CTP synthase activity
CLM75_RS06415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLM75_RS06420	COG0148	phosphopyruvate hydratase activity
CLM75_RS06430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CLM75_RS06440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CLM75_RS06445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CLM75_RS06450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLM75_RS06455	COG0585	pseudouridine synthase activity
CLM75_RS06460	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLM75_RS06465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CLM75_RS06485	COG1278	Cold shock
CLM75_RS06490	COG0717	Belongs to the dCTP deaminase family
CLM75_RS06505	COG1201	RNA secondary structure unwinding
CLM75_RS06535	COG1793	dna ligase
CLM75_RS06545	COG2366	antibiotic biosynthetic process
CLM75_RS06550	COG0625	glutathione transferase activity
CLM75_RS06555	COG0653	protein targeting
CLM75_RS06565	COG3012	SEC-C Motif Domain Protein
CLM75_RS06590	COG1199	ATP-dependent helicase activity
CLM75_RS06600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLM75_RS06610	COG0259	pyridoxamine-phosphate oxidase activity
CLM75_RS06625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLM75_RS06635	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CLM75_RS06650	COG0583	DNA-binding transcription factor activity
CLM75_RS06665	COG3220	belongs to the UPF0276 family
CLM75_RS06725	COG2271	Major facilitator Superfamily
CLM75_RS06730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLM75_RS06740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLM75_RS06750	COG0583	DNA-binding transcription factor activity
CLM75_RS06755	COG0306	phosphate transporter
CLM75_RS06765	COG1414	Transcriptional regulator
CLM75_RS06770	COG2814	Major facilitator Superfamily
CLM75_RS06775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLM75_RS06780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CLM75_RS06785	COG0183	Belongs to the thiolase family
CLM75_RS06790	COG3485	protocatechuate 3,4-dioxygenase
CLM75_RS06795	COG3485	protocatechuate 3,4-dioxygenase
CLM75_RS06800	COG0477	Major facilitator Superfamily
CLM75_RS06810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM75_RS06815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM75_RS06840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS06845	COG1309	transcriptional regulator
CLM75_RS06850	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS06855	COG2814	Major facilitator Superfamily
CLM75_RS06890	COG1473	amidohydrolase
CLM75_RS06900	COG0154	amidase activity
CLM75_RS06915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM75_RS06925	COG1704	LemA family
CLM75_RS06945	COG0697	spore germination
CLM75_RS06950	COG1629	transport
CLM75_RS06960	COG1595	DNA-templated transcription, initiation
CLM75_RS06965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM75_RS06970	COG0235	Class ii aldolase
CLM75_RS06975	COG1396	sequence-specific DNA binding
CLM75_RS06985	COG1454	alcohol dehydrogenase
CLM75_RS07005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM75_RS07010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM75_RS07015	COG2271	Major facilitator Superfamily
CLM75_RS07055	COG0583	DNA-binding transcription factor activity
CLM75_RS07060	COG2814	Major facilitator Superfamily
CLM75_RS07090	COG2267	carboxylic ester hydrolase activity
CLM75_RS07120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLM75_RS07170	COG0642	Histidine kinase
CLM75_RS07185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLM75_RS07220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLM75_RS07230	COG0425	Belongs to the sulfur carrier protein TusA family
CLM75_RS07240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLM75_RS07250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM75_RS07255	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CLM75_RS07260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLM75_RS07265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CLM75_RS07285	COG2205	protein histidine kinase activity
CLM75_RS07285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS07290	COG2197	response regulator
CLM75_RS07310	COG1595	DNA-templated transcription, initiation
CLM75_RS07320	COG0583	DNA-binding transcription factor activity
CLM75_RS07325	COG0477	Major facilitator Superfamily
CLM75_RS07340	COG0583	DNA-binding transcription factor activity
CLM75_RS07360	COG1802	Transcriptional regulator
CLM75_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS07370	COG3246	L-lysine catabolic process to acetate
CLM75_RS07405	COG2807	transmembrane transport
CLM75_RS07420	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS07430	COG0583	DNA-binding transcription factor activity
CLM75_RS07435	COG2910	NAD(P)H-binding
CLM75_RS07445	COG0583	DNA-binding transcription factor activity
CLM75_RS07475	COG0174	glutamine synthetase
CLM75_RS07490	COG3100	YcgL domain-containing protein
CLM75_RS07495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM75_RS07505	COG2983	Belongs to the UPF0260 family
CLM75_RS07550	COG1770	oligopeptidase
CLM75_RS07560	COG0121	glutamine amidotransferase
CLM75_RS07570	COG0583	DNA-binding transcription factor activity
CLM75_RS07575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLM75_RS07580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLM75_RS07585	COG1984	allophanate hydrolase subunit 2
CLM75_RS07600	COG0542	response to heat
CLM75_RS07610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLM75_RS07625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CLM75_RS07630	COG0425	Belongs to the sulfur carrier protein TusA family
CLM75_RS07640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM75_RS07645	COG1132	(ABC) transporter
CLM75_RS07650	COG0741	lytic transglycosylase activity
CLM75_RS07655	COG0488	(ABC) transporter
CLM75_RS07660	COG0589	response to stress
CLM75_RS07670	COG1024	Enoyl-CoA hydratase
CLM75_RS07670	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM75_RS07675	COG0183	Belongs to the thiolase family
CLM75_RS07720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLM75_RS07730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLM75_RS07745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM75_RS07750	COG0584	glycerophosphoryl diester phosphodiesterase
CLM75_RS07760	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLM75_RS07765	COG1136	(ABC) transporter
CLM75_RS07770	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLM75_RS07790	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLM75_RS07790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLM75_RS07805	COG2853	Lipoprotein
CLM75_RS07820	COG2204	response regulator
CLM75_RS07830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLM75_RS07835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLM75_RS07845	COG2814	Major facilitator Superfamily
CLM75_RS07850	COG0579	oxidoreductase
CLM75_RS07860	COG0583	DNA-binding transcription factor activity
CLM75_RS07880	COG0251	oxidation-reduction process
CLM75_RS07885	COG1611	Belongs to the LOG family
CLM75_RS07895	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CLM75_RS07905	COG0583	DNA-binding transcription factor activity
CLM75_RS07910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM75_RS07915	COG0583	DNA-binding transcription factor activity
CLM75_RS07920	COG2814	Major facilitator Superfamily
CLM75_RS07930	COG2233	PERMEase
CLM75_RS07940	COG2197	response regulator
CLM75_RS07945	COG0596	Alpha beta hydrolase
CLM75_RS07955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM75_RS07960	COG0444	Belongs to the ABC transporter superfamily
CLM75_RS07965	COG4608	Belongs to the ABC transporter superfamily
CLM75_RS07970	COG0747	negative chemotaxis
CLM75_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS07980	COG0546	phosphoglycolate phosphatase activity
CLM75_RS07985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLM75_RS07990	COG0402	S-adenosylhomocysteine deaminase activity
CLM75_RS07995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CLM75_RS08005	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLM75_RS08015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM75_RS08020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLM75_RS08025	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CLM75_RS08040	COG0776	regulation of translation
CLM75_RS08075	COG2244	polysaccharide biosynthetic process
CLM75_RS08105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLM75_RS08110	COG0438	transferase activity, transferring glycosyl groups
CLM75_RS08120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLM75_RS08145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM75_RS08150	COG1555	photosystem II stabilization
CLM75_RS08185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CLM75_RS08195	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLM75_RS08200	COG2205	protein histidine kinase activity
CLM75_RS08205	COG0745	RESPONSE REGULATOR receiver
CLM75_RS08240	COG3209	COG3209 Rhs family protein
CLM75_RS08240	COG3209	COG3209 Rhs family protein
CLM75_RS08250	COG0084	hydrolase, TatD family'
CLM75_RS08255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CLM75_RS08260	COG2259	Doxx family
CLM75_RS08280	COG1131	(ABC) transporter
CLM75_RS08290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM75_RS08295	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CLM75_RS08300	COG4181	ATPase activity
CLM75_RS08315	COG1376	ErfK ybiS ycfS ynhG family protein
CLM75_RS08345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLM75_RS08365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM75_RS08380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLM75_RS08390	COG1764	response to oxidative stress
CLM75_RS08395	COG1846	Transcriptional regulator
CLM75_RS08400	COG0583	DNA-binding transcription factor activity
CLM75_RS08405	COG0730	response to heat
CLM75_RS08410	COG0583	DNA-binding transcription factor activity
CLM75_RS08420	COG3214	Protein conserved in bacteria
CLM75_RS08425	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CLM75_RS08450	COG3384	dioxygenase
CLM75_RS08455	COG0500	methyltransferase
CLM75_RS08460	COG0501	Belongs to the peptidase M48B family
CLM75_RS08465	COG0436	Aminotransferase
CLM75_RS08470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM75_RS08475	COG0386	Belongs to the glutathione peroxidase family
CLM75_RS08480	COG1846	Transcriptional regulator
CLM75_RS08495	COG1956	GAF domain-containing protein
CLM75_RS08500	COG2205	protein histidine kinase activity
CLM75_RS08500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS08505	COG2197	response regulator
CLM75_RS08510	COG2204	response regulator
CLM75_RS08520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CLM75_RS08545	COG0004	ammonium transporteR
CLM75_RS08565	COG0564	pseudouridine synthase activity
CLM75_RS08575	COG0746	molybdenum cofactor guanylyltransferase activity
CLM75_RS08580	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLM75_RS08585	COG0303	'Molybdopterin
CLM75_RS08590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLM75_RS08600	COG4133	protoheme IX ABC transporter activity
CLM75_RS08620	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLM75_RS08625	COG1138	Cytochrome C-type biogenesis protein
CLM75_RS08635	COG3088	subunit of a heme lyase
CLM75_RS08640	COG4235	cytochrome complex assembly
CLM75_RS08650	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CLM75_RS08655	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CLM75_RS08660	COG3639	organic phosphonate transmembrane transporter activity
CLM75_RS08665	COG2188	Transcriptional regulator
CLM75_RS08670	COG3624	Phosphonate C-P lyase system protein PhnG
CLM75_RS08680	COG3626	phosphonate metabolism
CLM75_RS08685	COG3627	carbon phosphorus lyase activity
CLM75_RS08690	COG4107	phosphonate C-P lyase system protein PhnK
CLM75_RS08695	COG4778	phosphonate C-P lyase system protein PhnL
CLM75_RS08700	COG3454	Phosphonate metabolism
CLM75_RS08705	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CLM75_RS08710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLM75_RS08735	COG2814	Major facilitator Superfamily
CLM75_RS08750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM75_RS08760	COG0469	pyruvate kinase activity
CLM75_RS08770	COG2084	Dehydrogenase
CLM75_RS08775	COG3622	Belongs to the hyi family
CLM75_RS08780	COG3960	tartronate-semialdehyde synthase activity
CLM75_RS08795	COG1309	transcriptional regulator
CLM75_RS08800	COG2354	Protein conserved in bacteria
CLM75_RS08805	COG2853	Lipoprotein
CLM75_RS08825	COG2113	Glycine betaine
CLM75_RS08830	COG3162	membrane
CLM75_RS08835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLM75_RS08845	COG2009	succinate dehydrogenase
CLM75_RS08850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLM75_RS08855	COG1053	succinate dehydrogenase
CLM75_RS08860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLM75_RS08875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM75_RS08880	COG0045	succinate-CoA ligase (ADP-forming) activity
CLM75_RS08915	COG0326	Molecular chaperone. Has ATPase activity
CLM75_RS08925	COG1741	Belongs to the pirin family
CLM75_RS08940	COG0840	transmembrane signaling receptor activity
CLM75_RS08950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLM75_RS08955	COG2205	protein histidine kinase activity
CLM75_RS08955	COG5002	protein histidine kinase activity
CLM75_RS08955	COG0784	Response regulator, receiver
CLM75_RS08965	COG4771	TonB-dependent receptor
CLM75_RS08970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLM75_RS08985	COG1022	Amp-dependent synthetase and ligase
CLM75_RS09010	COG0628	permease
CLM75_RS09025	COG0284	orotidine-5'-phosphate decarboxylase activity
CLM75_RS09035	COG2130	NADP-dependent
CLM75_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS09045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS09050	COG0840	transmembrane signaling receptor activity
CLM75_RS09055	COG2267	carboxylic ester hydrolase activity
CLM75_RS09085	COG2197	response regulator
CLM75_RS09090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLM75_RS09105	COG2871	sodium ion transport
CLM75_RS09120	COG0811	peptide transport
CLM75_RS09145	COG3540	Alkaline phosphatase
CLM75_RS09150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLM75_RS09165	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS09175	COG0625	glutathione transferase activity
CLM75_RS09180	COG1131	(ABC) transporter
CLM75_RS09185	COG0842	Transport permease protein
CLM75_RS09210	COG0477	Major facilitator Superfamily
CLM75_RS09215	COG2076	Multidrug Resistance protein
CLM75_RS09220	COG0385	Bile acid
CLM75_RS09225	COG2974	May be involved in recombination
CLM75_RS09245	COG3712	iron ion homeostasis
CLM75_RS09250	COG1595	DNA-templated transcription, initiation
CLM75_RS09280	COG0745	RESPONSE REGULATOR receiver
CLM75_RS09285	COG2205	protein histidine kinase activity
CLM75_RS09290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CLM75_RS09295	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLM75_RS09300	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CLM75_RS09315	COG2010	Cytochrome c
CLM75_RS09320	COG0545	Peptidyl-prolyl cis-trans isomerase
CLM75_RS09340	COG2200	EAL domain
CLM75_RS09350	COG0604	alcohol dehydrogenase
CLM75_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLM75_RS09350	COG3321	synthase
CLM75_RS09350	COG4221	oxidoreductase activity
CLM75_RS09360	COG3842	ATPase activity
CLM75_RS09370	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM75_RS09400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLM75_RS09405	COG1121	(ABC) transporter
CLM75_RS09435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLM75_RS09440	COG0066	3-isopropylmalate dehydratase activity
CLM75_RS09445	COG0583	DNA-binding transcription factor activity
CLM75_RS09450	COG1301	dicarboxylic acid transport
CLM75_RS09455	COG0596	Alpha beta hydrolase
CLM75_RS09470	COG3829	transcription factor binding
CLM75_RS09480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS09485	COG0431	NADPH-dependent FMN reductase
CLM75_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS09540	COG5006	permease, DMT superfamily
CLM75_RS09575	COG0768	penicillin binding
CLM75_RS09595	COG0417	DNA replication proofreading
CLM75_RS09620	COG0728	peptidoglycan biosynthetic process
CLM75_RS09645	COG0297	glycogen (starch) synthase activity
CLM75_RS09665	COG0662	Cupin 2, conserved barrel domain protein
CLM75_RS09665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CLM75_RS09670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CLM75_RS09685	COG4977	sequence-specific DNA binding
CLM75_RS09690	COG0596	Alpha beta hydrolase
CLM75_RS09700	COG3387	PFAM Glycoside hydrolase 15-related
CLM75_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS09710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM75_RS09715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLM75_RS09725	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS09745	COG0529	Catalyzes the synthesis of activated sulfate
CLM75_RS09755	COG1595	DNA-templated transcription, initiation
CLM75_RS09765	COG4772	TonB-dependent receptor
CLM75_RS09790	COG2223	nitrite transmembrane transporter activity
CLM75_RS09795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLM75_RS09815	COG3675	Pfam Lipase (class 3)
CLM75_RS09820	COG0402	S-adenosylhomocysteine deaminase activity
CLM75_RS09830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLM75_RS09835	COG1051	belongs to the nudix hydrolase family
CLM75_RS09845	COG0720	synthase
CLM75_RS09875	COG0840	transmembrane signaling receptor activity
CLM75_RS09880	COG2056	Na+-H+ antiporter family
CLM75_RS09890	COG0826	peptidase U32
CLM75_RS09905	COG0628	permease
CLM75_RS09920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLM75_RS09925	COG3132	Protein of unknown function, DUF480
CLM75_RS09935	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CLM75_RS09945	COG0583	DNA-binding transcription factor activity
CLM75_RS09955	COG1253	flavin adenine dinucleotide binding
CLM75_RS09960	COG0709	Synthesizes selenophosphate from selenide and ATP
CLM75_RS09965	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CLM75_RS09970	COG0701	Predicted permease
CLM75_RS09980	COG0625	glutathione transferase activity
CLM75_RS09985	COG0384	phenazine biosynthesis protein PhzF
CLM75_RS09990	COG0113	porphobilinogen synthase activity
CLM75_RS10025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLM75_RS10030	COG0583	DNA-binding transcription factor activity
CLM75_RS10040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CLM75_RS10045	COG0517	IMP dehydrogenase activity
CLM75_RS10050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLM75_RS10075	COG4335	DNA alkylation repair
CLM75_RS10080	COG0174	glutamine synthetase
CLM75_RS10100	COG2814	Major facilitator Superfamily
CLM75_RS10110	COG3237	CsbD-like
CLM75_RS10135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS10165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLM75_RS10175	COG2197	response regulator
CLM75_RS10180	COG2205	protein histidine kinase activity
CLM75_RS10180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS10190	COG0656	L-ascorbic acid biosynthetic process
CLM75_RS10195	COG1309	transcriptional regulator
CLM75_RS10200	COG1024	Enoyl-CoA hydratase
CLM75_RS10205	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS10220	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM75_RS10225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLM75_RS10230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS10250	COG2197	response regulator
CLM75_RS10255	COG0322	excinuclease ABC activity
CLM75_RS10280	COG2200	EAL domain
CLM75_RS10280	COG2199	diguanylate cyclase activity
CLM75_RS10280	COG2202	Pas domain
CLM75_RS10285	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CLM75_RS10290	COG2197	response regulator
CLM75_RS10305	COG0784	Response regulator, receiver
CLM75_RS10305	COG4191	Histidine kinase
CLM75_RS10320	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS10320	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLM75_RS10325	COG2113	Glycine betaine
CLM75_RS10345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM75_RS10350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS10380	COG4214	carbohydrate transport
CLM75_RS10385	COG1129	ABC transporter
CLM75_RS10390	COG4213	ABC transporter substrate-binding protein
CLM75_RS10395	COG2115	Belongs to the xylose isomerase family
CLM75_RS10400	COG1609	Transcriptional regulator
CLM75_RS10400	COG2207	Transcriptional regulator
CLM75_RS10420	COG3781	membrane
CLM75_RS10430	COG2199	diguanylate cyclase activity
CLM75_RS10440	COG0640	Transcriptional regulator
CLM75_RS10445	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS10450	COG2135	peptidase activity
CLM75_RS10480	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS10490	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS10495	COG1129	ABC transporter
CLM75_RS10500	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS10525	COG0583	DNA-binding transcription factor activity
CLM75_RS10530	COG2957	Belongs to the agmatine deiminase family
CLM75_RS10545	COG2957	Belongs to the agmatine deiminase family
CLM75_RS10550	COG0625	glutathione transferase activity
CLM75_RS10555	COG1968	undecaprenyl-diphosphatase activity
CLM75_RS10565	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS10570	COG3321	synthase
CLM75_RS10570	COG0604	alcohol dehydrogenase
CLM75_RS10580	COG0583	DNA-binding transcription factor activity
CLM75_RS10595	COG1064	alcohol dehydrogenase
CLM75_RS10600	COG1971	Probably functions as a manganese efflux pump
CLM75_RS10610	COG0583	DNA-binding transcription factor activity
CLM75_RS10640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLM75_RS10640	COG0475	glutathione-regulated potassium exporter activity
CLM75_RS10650	COG0697	spore germination
CLM75_RS10655	COG0367	asparagine synthase
CLM75_RS10665	COG1024	Enoyl-CoA hydratase
CLM75_RS10670	COG2207	Transcriptional regulator
CLM75_RS10770	COG2204	response regulator
CLM75_RS10775	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CLM75_RS10785	COG3046	protein related to deoxyribodipyrimidine photolyase
CLM75_RS10790	COG1366	Belongs to the anti-sigma-factor antagonist family
CLM75_RS10805	COG0302	gtp cyclohydrolase
CLM75_RS10815	COG2351	hydroxyisourate hydrolase activity
CLM75_RS10855	COG1177	transmembrane transport
CLM75_RS10860	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM75_RS10865	COG3842	ATPase activity
CLM75_RS10870	COG1414	Transcriptional regulator
CLM75_RS10880	COG0784	Response regulator, receiver
CLM75_RS10880	COG2198	Histidine kinase
CLM75_RS10880	COG2205	protein histidine kinase activity
CLM75_RS10880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS10900	COG3842	ATPase activity
CLM75_RS10915	COG0840	transmembrane signaling receptor activity
CLM75_RS10930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS10940	COG0534	Mate efflux family protein
CLM75_RS10945	COG1309	transcriptional regulator
CLM75_RS11025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS11030	COG1136	(ABC) transporter
CLM75_RS11030	COG0577	efflux transmembrane transporter activity
CLM75_RS11045	COG1522	sequence-specific DNA binding
CLM75_RS11050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM75_RS11060	COG2814	Major facilitator Superfamily
CLM75_RS11075	COG0174	glutamine synthetase
CLM75_RS11085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS11090	COG0583	DNA-binding transcription factor activity
CLM75_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS11110	COG5002	protein histidine kinase activity
CLM75_RS11115	COG0745	RESPONSE REGULATOR receiver
CLM75_RS11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS11150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS11160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM75_RS11170	COG3718	enzyme involved in inositol metabolism
CLM75_RS11180	COG3962	Belongs to the TPP enzyme family
CLM75_RS11185	COG0673	inositol 2-dehydrogenase activity
CLM75_RS11190	COG0673	inositol 2-dehydrogenase activity
CLM75_RS11205	COG1129	ABC transporter
CLM75_RS11210	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS11220	COG0840	transmembrane signaling receptor activity
CLM75_RS11275	COG3209	COG3209 Rhs family protein
CLM75_RS11280	COG4774	siderophore transport
CLM75_RS11290	COG0583	DNA-binding transcription factor activity
CLM75_RS11300	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM75_RS11320	COG5001	Diguanylate cyclase
CLM75_RS11320	COG4251	negative regulation of phosphorylation
CLM75_RS11320	COG2203	Gaf domain
CLM75_RS11320	COG3706	GGDEF domain
CLM75_RS11360	COG0616	signal peptide processing
CLM75_RS11375	COG1253	flavin adenine dinucleotide binding
CLM75_RS11395	COG0765	amino acid transport
CLM75_RS11400	COG0765	amino acid transport
CLM75_RS11425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM75_RS11430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM75_RS11440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM75_RS11445	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS11450	COG2610	gluconate transmembrane transporter activity
CLM75_RS11455	COG3290	protein histidine kinase activity
CLM75_RS11455	COG3829	transcription factor binding
CLM75_RS11460	COG4172	Belongs to the ABC transporter superfamily
CLM75_RS11465	COG4239	(ABC) transporter, permease
CLM75_RS11470	COG4174	ABC transporter (Permease)
CLM75_RS11475	COG4166	transmembrane transport
CLM75_RS11480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM75_RS11485	COG4172	Belongs to the ABC transporter superfamily
CLM75_RS11490	COG4239	(ABC) transporter, permease
CLM75_RS11495	COG4174	ABC transporter (Permease)
CLM75_RS11500	COG4166	transmembrane transport
CLM75_RS11505	COG4166	transmembrane transport
CLM75_RS11515	COG0741	lytic transglycosylase activity
CLM75_RS11515	COG1388	LysM domain
CLM75_RS11520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLM75_RS11530	COG0328	RNA-DNA hybrid ribonuclease activity
CLM75_RS11535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLM75_RS11565	COG0431	NADPH-dependent FMN reductase
CLM75_RS11570	COG0028	Belongs to the TPP enzyme family
CLM75_RS11580	COG0789	Transcriptional regulator
CLM75_RS11600	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS11630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CLM75_RS11630	COG0316	Belongs to the HesB IscA family
CLM75_RS11680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLM75_RS11685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM75_RS11690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLM75_RS11705	COG3139	Protein of unknown function (DUF1315)
CLM75_RS11715	COG0308	aminopeptidase N
CLM75_RS11720	COG0667	Aldo Keto reductase
CLM75_RS11735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLM75_RS11755	COG2194	sulfuric ester hydrolase activity
CLM75_RS11760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CLM75_RS11765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLM75_RS11770	COG0561	phosphatase activity
CLM75_RS11860	COG2233	PERMEase
CLM75_RS11880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM75_RS11890	COG1609	Transcriptional regulator
CLM75_RS11910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS11915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS11920	COG0745	RESPONSE REGULATOR receiver
CLM75_RS11925	COG2205	protein histidine kinase activity
CLM75_RS11950	COG0730	response to heat
CLM75_RS11960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS11970	COG0189	ligase activity
CLM75_RS11975	COG0598	Magnesium transport protein CorA
CLM75_RS11980	COG0024	Methionine aminopeptidase
CLM75_RS11990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLM75_RS12015	COG1070	Carbohydrate kinase
CLM75_RS12035	COG1175	transmembrane transport
CLM75_RS12070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS12080	COG1538	Outer membrane efflux protein
CLM75_RS12090	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS12095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS12100	COG0348	domain, Protein
CLM75_RS12110	COG1285	pathogenesis
CLM75_RS12125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM75_RS12135	COG0784	Response regulator, receiver
CLM75_RS12135	COG4191	Histidine kinase
CLM75_RS12145	COG0477	Major facilitator Superfamily
CLM75_RS12175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLM75_RS12180	COG3012	SEC-C Motif Domain Protein
CLM75_RS12180	COG3318	Belongs to the UPF0149 family
CLM75_RS12185	COG0038	chloride channel
CLM75_RS12190	COG1024	Enoyl-CoA hydratase
CLM75_RS12195	COG2816	NAD+ diphosphatase activity
CLM75_RS12225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLM75_RS12255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLM75_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS12275	COG3254	rhamnose metabolic process
CLM75_RS12285	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS12295	COG4948	Mandelate Racemase Muconate Lactonizing
CLM75_RS12300	COG2271	Major facilitator Superfamily
CLM75_RS12310	COG1595	DNA-templated transcription, initiation
CLM75_RS12315	COG3712	iron ion homeostasis
CLM75_RS12320	COG1116	anion transmembrane transporter activity
CLM75_RS12325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM75_RS12340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CLM75_RS12350	COG2271	Major facilitator Superfamily
CLM75_RS12355	COG1335	isochorismatase
CLM75_RS12360	COG3473	Maleate cis-trans isomerase
CLM75_RS12365	COG0596	Alpha beta hydrolase
CLM75_RS12370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM75_RS12375	COG2309	aminopeptidase activity
CLM75_RS12380	COG1846	Transcriptional regulator
CLM75_RS12385	COG2080	2 iron, 2 sulfur cluster binding
CLM75_RS12390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLM75_RS12390	COG2010	Cytochrome c
CLM75_RS12395	COG1309	transcriptional regulator
CLM75_RS12410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM75_RS12425	COG0840	transmembrane signaling receptor activity
CLM75_RS12430	COG1968	undecaprenyl-diphosphatase activity
CLM75_RS12445	COG0583	DNA-binding transcription factor activity
CLM75_RS12450	COG4753	response regulator
CLM75_RS12450	COG2207	Transcriptional regulator
CLM75_RS12460	COG1966	Carbon starvation protein
CLM75_RS12465	COG2879	small protein
CLM75_RS12480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLM75_RS12495	COG0488	(ABC) transporter
CLM75_RS12530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CLM75_RS12540	COG2133	pyrroloquinoline quinone binding
CLM75_RS12555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM75_RS12560	COG2822	iron ion transport
CLM75_RS12570	COG2822	iron ion transport
CLM75_RS12575	COG0672	)-iron permease
CLM75_RS12600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS12610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLM75_RS12620	COG0747	negative chemotaxis
CLM75_RS12640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CLM75_RS12655	COG2814	Major facilitator Superfamily
CLM75_RS12675	COG4221	oxidoreductase activity
CLM75_RS12680	COG2207	Transcriptional regulator
CLM75_RS12730	COG0778	Nitroreductase
CLM75_RS12740	COG1942	4-Oxalocrotonate Tautomerase
CLM75_RS12770	COG3321	synthase
CLM75_RS12770	COG0604	alcohol dehydrogenase
CLM75_RS12770	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS12780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS12795	COG0210	DNA helicase
CLM75_RS12810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS12830	COG1113	amino acid transport
CLM75_RS12865	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CLM75_RS12880	COG1199	ATP-dependent helicase activity
CLM75_RS12885	COG2267	carboxylic ester hydrolase activity
CLM75_RS12895	COG0745	RESPONSE REGULATOR receiver
CLM75_RS12905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM75_RS12915	COG2308	Evidence 4 Homologs of previously reported genes of
CLM75_RS12955	COG0697	spore germination
CLM75_RS12960	COG1309	transcriptional regulator
CLM75_RS12970	COG2207	Transcriptional regulator
CLM75_RS12990	COG0583	DNA-binding transcription factor activity
CLM75_RS12995	COG5001	Diguanylate cyclase
CLM75_RS12995	COG1716	ATPase activity
CLM75_RS13000	COG0784	Response regulator, receiver
CLM75_RS13005	COG2202	Pas domain
CLM75_RS13005	COG2205	protein histidine kinase activity
CLM75_RS13010	COG0642	Histidine kinase
CLM75_RS13025	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS13035	COG1022	Amp-dependent synthetase and ligase
CLM75_RS13045	COG3038	cytochrome b561
CLM75_RS13055	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS13060	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS13065	COG1609	Transcriptional regulator
CLM75_RS13070	COG1070	Carbohydrate kinase
CLM75_RS13080	COG1522	sequence-specific DNA binding
CLM75_RS13090	COG0826	peptidase U32
CLM75_RS13100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM75_RS13120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CLM75_RS13210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS13230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLM75_RS13250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CLM75_RS13285	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM75_RS13290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS13310	COG2207	Transcriptional regulator
CLM75_RS13325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS13330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS13370	COG0402	S-adenosylhomocysteine deaminase activity
CLM75_RS13375	COG0583	DNA-binding transcription factor activity
CLM75_RS13380	COG2807	transmembrane transport
CLM75_RS13385	COG2207	Transcriptional regulator
CLM75_RS13400	COG0473	3-isopropylmalate dehydrogenase activity
CLM75_RS13425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS13435	COG2113	Glycine betaine
CLM75_RS13440	COG0583	DNA-binding transcription factor activity
CLM75_RS13470	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLM75_RS13490	COG0431	NADPH-dependent FMN reductase
CLM75_RS13505	COG2273	Hydrolase Family 16
CLM75_RS13520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM75_RS13525	COG2301	Belongs to the HpcH HpaI aldolase family
CLM75_RS13535	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM75_RS13565	COG2030	dehydratase
CLM75_RS13575	COG2188	Transcriptional regulator
CLM75_RS13580	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS13590	COG1917	Cupin 2, conserved barrel domain protein
CLM75_RS13590	COG4977	sequence-specific DNA binding
CLM75_RS13615	COG0583	DNA-binding transcription factor activity
CLM75_RS13620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLM75_RS13660	COG2814	Major facilitator Superfamily
CLM75_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS13685	COG0371	Dehydrogenase
CLM75_RS13705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS13715	COG0583	DNA-binding transcription factor activity
CLM75_RS13730	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM75_RS13735	COG3246	L-lysine catabolic process to acetate
CLM75_RS13745	COG2721	sulfolactate sulfo-lyase activity
CLM75_RS13750	COG1802	Transcriptional regulator
CLM75_RS13755	COG3386	PFAM SMP-30 Gluconolaconase
CLM75_RS13775	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS13810	COG2433	Pfam Transposase IS66
CLM75_RS13830	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLM75_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS13850	COG0840	transmembrane signaling receptor activity
CLM75_RS13855	COG2814	Major facilitator Superfamily
CLM75_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS13865	COG4974	Belongs to the 'phage' integrase family
CLM75_RS13875	COG0463	Glycosyl transferase, family 2
CLM75_RS13880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM75_RS13880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLM75_RS13885	COG0726	polysaccharide deacetylase
CLM75_RS13890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLM75_RS13895	COG2076	Multidrug Resistance protein
CLM75_RS13900	COG2076	Multidrug Resistance protein
CLM75_RS13925	COG1024	Enoyl-CoA hydratase
CLM75_RS13930	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS13940	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS13955	COG3781	membrane
CLM75_RS13965	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CLM75_RS13985	COG0784	Response regulator, receiver
CLM75_RS13985	COG2205	protein histidine kinase activity
CLM75_RS13995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM75_RS14000	COG0784	Response regulator, receiver
CLM75_RS14000	COG2205	protein histidine kinase activity
CLM75_RS14000	COG2198	Histidine kinase
CLM75_RS14030	COG3278	Belongs to the heme-copper respiratory oxidase family
CLM75_RS14040	COG1794	racemase activity, acting on amino acids and derivatives
CLM75_RS14045	COG1247	-acetyltransferase
CLM75_RS14050	COG5342	invasion associated locus B
CLM75_RS14055	COG1929	Belongs to the glycerate kinase type-1 family
CLM75_RS14060	COG3835	regulator
CLM75_RS14065	COG2271	Major facilitator Superfamily
CLM75_RS14075	COG0583	DNA-binding transcription factor activity
CLM75_RS14080	COG0667	Aldo Keto reductase
CLM75_RS14100	COG0583	DNA-binding transcription factor activity
CLM75_RS14105	COG2200	EAL domain
CLM75_RS14180	COG3145	DNA-N1-methyladenine dioxygenase activity
CLM75_RS14185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLM75_RS14185	COG2169	Transcriptional regulator
CLM75_RS14215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CLM75_RS14245	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CLM75_RS14255	COG0640	Transcriptional regulator
CLM75_RS14265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLM75_RS14270	COG0431	NADPH-dependent FMN reductase
CLM75_RS14275	COG2207	Transcriptional regulator
CLM75_RS14275	COG1917	Cupin 2, conserved barrel domain protein
CLM75_RS14355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLM75_RS14360	COG0581	inorganic phosphate transmembrane transporter activity
CLM75_RS14370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLM75_RS14385	COG5290	Psort location Cytoplasmic, score
CLM75_RS14400	COG3938	Belongs to the proline racemase family
CLM75_RS14415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS14420	COG1397	ADP-ribosylglycohydrolase
CLM75_RS14505	COG2366	antibiotic biosynthetic process
CLM75_RS14520	COG0583	DNA-binding transcription factor activity
CLM75_RS14525	COG0667	Aldo Keto reductase
CLM75_RS14545	COG1238	metal cluster binding
CLM75_RS14550	COG0596	Alpha beta hydrolase
CLM75_RS14555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM75_RS14560	COG0297	glycogen (starch) synthase activity
CLM75_RS14565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLM75_RS14570	COG1640	4-alpha-glucanotransferase
CLM75_RS14625	COG1113	amino acid transport
CLM75_RS14635	COG1522	sequence-specific DNA binding
CLM75_RS14655	COG3011	Protein conserved in bacteria
CLM75_RS14660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLM75_RS14695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM75_RS14705	COG0626	cystathionine gamma-synthase activity
CLM75_RS14710	COG1944	ATP diphosphatase activity
CLM75_RS14715	COG0840	transmembrane signaling receptor activity
CLM75_RS14720	COG1280	lysine exporter protein (LysE YggA)
CLM75_RS14730	COG1309	transcriptional regulator
CLM75_RS14770	COG1247	-acetyltransferase
CLM75_RS14790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM75_RS14790	COG2146	nitrite reductase [NAD(P)H] activity
CLM75_RS14795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLM75_RS14795	COG2146	nitrite reductase [NAD(P)H] activity
CLM75_RS14800	COG0243	molybdopterin cofactor binding
CLM75_RS14840	COG2271	Major facilitator Superfamily
CLM75_RS14860	COG2207	Transcriptional regulator
CLM75_RS14875	COG2207	Transcriptional regulator
CLM75_RS14880	COG2223	nitrite transmembrane transporter activity
CLM75_RS14885	COG3300	MHYT domain
CLM75_RS14885	COG5001	Diguanylate cyclase
CLM75_RS14905	COG0154	amidase activity
CLM75_RS14925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS14930	COG0697	spore germination
CLM75_RS14990	COG2079	MmgE PrpD family protein
CLM75_RS14995	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS15000	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CLM75_RS15005	COG0583	DNA-binding transcription factor activity
CLM75_RS15025	COG0714	Associated with various cellular activities
CLM75_RS15030	COG3791	Glutathione-dependent formaldehyde-activating
CLM75_RS15040	COG2205	protein histidine kinase activity
CLM75_RS15045	COG0745	RESPONSE REGULATOR receiver
CLM75_RS15060	COG0662	Cupin 2, conserved barrel domain protein
CLM75_RS15075	COG0589	response to stress
CLM75_RS15090	COG0814	amino acid
CLM75_RS15100	COG1335	isochorismatase
CLM75_RS15105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM75_RS15115	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS15120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM75_RS15140	COG0519	Catalyzes the synthesis of GMP from XMP
CLM75_RS15185	COG0714	Associated with various cellular activities
CLM75_RS15230	COG0420	3'-5' exonuclease activity
CLM75_RS15250	COG2706	6-phosphogluconolactonase activity
CLM75_RS15275	COG0673	inositol 2-dehydrogenase activity
CLM75_RS15280	COG0318	PFAM AMP-dependent synthetase and ligase
CLM75_RS15285	COG0183	Belongs to the thiolase family
CLM75_RS15295	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS15310	COG2067	long-chain fatty acid transport protein
CLM75_RS15330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS15335	COG2267	carboxylic ester hydrolase activity
CLM75_RS15355	COG5001	Diguanylate cyclase
CLM75_RS15355	COG3300	MHYT domain
CLM75_RS15365	COG0515	serine threonine protein kinase
CLM75_RS15390	COG0656	L-ascorbic acid biosynthetic process
CLM75_RS15405	COG0596	Alpha beta hydrolase
CLM75_RS15415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLM75_RS15460	COG0477	Major facilitator Superfamily
CLM75_RS15470	COG0625	glutathione transferase activity
CLM75_RS15485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLM75_RS15510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLM75_RS15515	COG3842	ATPase activity
CLM75_RS15525	COG1175	transmembrane transport
CLM75_RS15545	COG0019	diaminopimelate decarboxylase activity
CLM75_RS15560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS15565	COG0765	amino acid transport
CLM75_RS15570	COG1126	abc transporter atp-binding protein
CLM75_RS15575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS15580	COG2066	Belongs to the glutaminase family
CLM75_RS15600	COG0673	inositol 2-dehydrogenase activity
CLM75_RS15625	COG5383	Protein conserved in bacteria
CLM75_RS15645	COG0784	Response regulator, receiver
CLM75_RS15645	COG4191	Histidine kinase
CLM75_RS15650	COG0587	DNA-directed DNA polymerase activity
CLM75_RS15665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLM75_RS15670	COG3209	COG3209 Rhs family protein
CLM75_RS15685	COG0494	nUDIX hydrolase
CLM75_RS15690	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS15700	COG1304	FMN binding
CLM75_RS15705	COG1349	DNA-binding transcription factor activity
CLM75_RS15725	COG0693	protein deglycase activity
CLM75_RS15760	COG1999	signal sequence binding
CLM75_RS15800	COG2072	flavoprotein involved in K transport
CLM75_RS15820	COG1609	Transcriptional regulator
CLM75_RS15825	COG2271	Major facilitator Superfamily
CLM75_RS15830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLM75_RS15840	COG0583	DNA-binding transcription factor activity
CLM75_RS15845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CLM75_RS15865	COG1595	DNA-templated transcription, initiation
CLM75_RS15870	COG3712	iron ion homeostasis
CLM75_RS15915	COG1959	2 iron, 2 sulfur cluster binding
CLM75_RS15930	COG2814	Major facilitator Superfamily
CLM75_RS15940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS15945	COG3209	COG3209 Rhs family protein
CLM75_RS15960	COG3209	COG3209 Rhs family protein
CLM75_RS15980	COG3706	GGDEF domain
CLM75_RS15985	COG1280	lysine exporter protein (LysE YggA)
CLM75_RS15990	COG2188	Transcriptional regulator
CLM75_RS16020	COG0583	DNA-binding transcription factor activity
CLM75_RS16030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLM75_RS16035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM75_RS16040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS16050	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS16055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM75_RS16085	COG3447	MASE1 domain protein
CLM75_RS16085	COG5001	Diguanylate cyclase
CLM75_RS16085	COG5002	protein histidine kinase activity
CLM75_RS16095	COG0583	DNA-binding transcription factor activity
CLM75_RS16100	COG1335	isochorismatase
CLM75_RS16105	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CLM75_RS16125	COG4977	sequence-specific DNA binding
CLM75_RS16125	COG1917	Cupin 2, conserved barrel domain protein
CLM75_RS16145	COG1741	Belongs to the pirin family
CLM75_RS16170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM75_RS16175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM75_RS16180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLM75_RS16185	COG3958	Transketolase
CLM75_RS16190	COG3959	Transketolase, thiamine diphosphate binding domain
CLM75_RS16195	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS16200	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS16205	COG1129	ABC transporter
CLM75_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS16225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLM75_RS16230	COG2814	Major facilitator Superfamily
CLM75_RS16280	COG0395	ABC-type sugar transport system, permease component
CLM75_RS16290	COG3842	ATPase activity
CLM75_RS16295	COG3842	ATPase activity
CLM75_RS16300	COG3284	Transcriptional regulator
CLM75_RS16310	COG1595	DNA-templated transcription, initiation
CLM75_RS16365	COG0251	oxidation-reduction process
CLM75_RS16385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLM75_RS16395	COG0038	chloride channel
CLM75_RS16445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLM75_RS16450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLM75_RS16455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLM75_RS16460	COG2835	tetraacyldisaccharide 4'-kinase activity
CLM75_RS16465	COG1663	tetraacyldisaccharide 4'-kinase activity
CLM75_RS16475	COG0811	peptide transport
CLM75_RS16480	COG2333	competence protein COMEC
CLM75_RS16480	COG0658	competence protein
CLM75_RS16500	COG2205	protein histidine kinase activity
CLM75_RS16500	COG0784	Response regulator, receiver
CLM75_RS16500	COG5002	protein histidine kinase activity
CLM75_RS16505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLM75_RS16525	COG1393	Belongs to the ArsC family
CLM75_RS16545	COG0037	tRNA processing
CLM75_RS16555	COG3091	SprT-like family
CLM75_RS16560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM75_RS16580	COG2920	part of a sulfur-relay system
CLM75_RS16585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLM75_RS16590	COG0435	Glutathione S-transferase
CLM75_RS16600	COG1648	precorrin-2 dehydrogenase activity
CLM75_RS16600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLM75_RS16605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLM75_RS16610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLM75_RS16615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLM75_RS16620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLM75_RS16625	COG1674	ftsk spoiiie
CLM75_RS16630	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CLM75_RS16635	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CLM75_RS16640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLM75_RS16645	COG0542	response to heat
CLM75_RS16650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLM75_RS16655	COG1278	Cold shock
CLM75_RS16680	COG0482	sulfurtransferase activity
CLM75_RS16685	COG2915	High frequency lysogenization protein hflD homolog
CLM75_RS16695	COG2850	peptidyl-arginine hydroxylation
CLM75_RS16700	COG2153	protein acetylation
CLM75_RS16715	COG2224	Isocitrate lyase
CLM75_RS16720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM75_RS16725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM75_RS16730	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM75_RS16730	COG0649	NAD binding
CLM75_RS16745	COG1034	ATP synthesis coupled electron transport
CLM75_RS16750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLM75_RS16755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLM75_RS16765	COG0713	ATP synthesis coupled electron transport
CLM75_RS16780	COG1007	ATP synthesis coupled electron transport
CLM75_RS16825	COG2814	Major facilitator Superfamily
CLM75_RS16830	COG0288	reversible hydration of carbon dioxide
CLM75_RS16845	COG3220	belongs to the UPF0276 family
CLM75_RS16890	COG1136	(ABC) transporter
CLM75_RS16890	COG0577	efflux transmembrane transporter activity
CLM75_RS16895	COG0577	efflux transmembrane transporter activity
CLM75_RS16895	COG1136	(ABC) transporter
CLM75_RS16905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS16970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLM75_RS16970	COG2111	Na H antiporter
CLM75_RS16975	COG1006	Multisubunit Na H antiporter MnhC subunit
CLM75_RS16980	COG0651	ATP synthesis coupled electron transport
CLM75_RS16990	COG2212	antiporter activity
CLM75_RS16995	COG1320	monovalent cation:proton antiporter activity
CLM75_RS17005	COG1733	regulation of RNA biosynthetic process
CLM75_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS17015	COG0681	Belongs to the peptidase S26 family
CLM75_RS17035	COG0215	cysteine-tRNA ligase activity
CLM75_RS17040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM75_RS17050	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLM75_RS17060	COG2814	Major facilitator Superfamily
CLM75_RS17065	COG1566	PFAM secretion protein HlyD family protein
CLM75_RS17075	COG1846	Transcriptional regulator
CLM75_RS17080	COG2911	Protein conserved in bacteria
CLM75_RS17085	COG0729	surface antigen
CLM75_RS17095	COG0708	Exodeoxyribonuclease III
CLM75_RS17105	COG2885	chlorophyll binding
CLM75_RS17110	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS17120	COG0789	Transcriptional regulator
CLM75_RS17130	COG0318	PFAM AMP-dependent synthetase and ligase
CLM75_RS17135	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS17140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLM75_RS17170	COG2866	Carboxypeptidase
CLM75_RS17175	COG3038	cytochrome b561
CLM75_RS17230	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLM75_RS17240	COG0217	transcriptional regulatory protein
CLM75_RS17255	COG0583	DNA-binding transcription factor activity
CLM75_RS17260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CLM75_RS17265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM75_RS17270	COG3038	cytochrome b561
CLM75_RS17280	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS17280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLM75_RS17295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLM75_RS17300	COG1846	Transcriptional regulator
CLM75_RS17305	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLM75_RS17315	COG0583	DNA-binding transcription factor activity
CLM75_RS17320	COG2814	Major facilitator Superfamily
CLM75_RS17330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM75_RS17335	COG0776	regulation of translation
CLM75_RS17340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLM75_RS17345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLM75_RS17350	COG0740	serine-type endopeptidase activity
CLM75_RS17355	COG0544	peptidyl-prolyl cis-trans isomerase activity
CLM75_RS17380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLM75_RS17385	COG1686	Belongs to the peptidase S11 family
CLM75_RS17405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS17420	COG1953	Uracil, thiamine, allantoin
CLM75_RS17440	COG1309	transcriptional regulator
CLM75_RS17445	COG0456	acetyltransferase
CLM75_RS17465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLM75_RS17490	COG0471	metal ion transport
CLM75_RS17505	COG0640	Transcriptional regulator
CLM75_RS17515	COG1522	sequence-specific DNA binding
CLM75_RS17520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CLM75_RS17525	COG0022	dehydrogenase e1 component
CLM75_RS17535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLM75_RS17540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLM75_RS17550	COG2423	ornithine cyclodeaminase activity
CLM75_RS17580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS17585	COG1136	(ABC) transporter
CLM75_RS17585	COG0577	efflux transmembrane transporter activity
CLM75_RS17600	COG2186	Transcriptional regulator
CLM75_RS17655	COG1609	Transcriptional regulator
CLM75_RS17660	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS17665	COG1070	Carbohydrate kinase
CLM75_RS17670	COG1063	alcohol dehydrogenase
CLM75_RS17675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS17685	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS17735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLM75_RS17740	COG1129	ABC transporter
CLM75_RS17770	COG0583	DNA-binding transcription factor activity
CLM75_RS17780	COG0625	glutathione transferase activity
CLM75_RS17785	COG0390	transport system, permease component
CLM75_RS17790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLM75_RS17795	COG0667	Aldo Keto reductase
CLM75_RS17825	COG2205	protein histidine kinase activity
CLM75_RS17825	COG0784	Response regulator, receiver
CLM75_RS17830	COG2203	Gaf domain
CLM75_RS17830	COG2200	EAL domain
CLM75_RS17830	COG2199	diguanylate cyclase activity
CLM75_RS17835	COG0784	Response regulator, receiver
CLM75_RS17835	COG2205	protein histidine kinase activity
CLM75_RS17840	COG2197	response regulator
CLM75_RS17850	COG3121	Chaperone
CLM75_RS17870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS17875	COG0765	amino acid transport
CLM75_RS17885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS17900	COG1231	oxidoreductase activity
CLM75_RS17905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS17910	COG1126	abc transporter atp-binding protein
CLM75_RS17925	COG1450	Type ii and iii secretion system protein
CLM75_RS17940	COG3166	PFAM Fimbrial assembly family protein
CLM75_RS17945	COG3156	type II secretion system protein K
CLM75_RS17965	COG2165	general secretion pathway protein
CLM75_RS17970	COG1459	type II secretion system
CLM75_RS17975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLM75_RS17980	COG1609	Transcriptional regulator
CLM75_RS17990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS17995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM75_RS18000	COG1120	ATPase activity
CLM75_RS18005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM75_RS18010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM75_RS18015	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CLM75_RS18020	COG4774	siderophore transport
CLM75_RS18030	COG1309	transcriptional regulator
CLM75_RS18040	COG1063	alcohol dehydrogenase
CLM75_RS18045	COG2199	diguanylate cyclase activity
CLM75_RS18080	COG0776	regulation of translation
CLM75_RS18085	COG0072	phenylalanine-tRNA ligase activity
CLM75_RS18090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLM75_RS18095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLM75_RS18100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CLM75_RS18105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLM75_RS18110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLM75_RS18120	COG1278	Cold shock
CLM75_RS18145	COG1869	D-ribose catabolic process
CLM75_RS18150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLM75_RS18155	COG1609	Transcriptional regulator
CLM75_RS18160	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS18165	COG1129	ABC transporter
CLM75_RS18170	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS18195	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLM75_RS18210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM75_RS18230	COG5002	protein histidine kinase activity
CLM75_RS18260	COG0477	Major facilitator Superfamily
CLM75_RS18270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS18305	COG1286	toxin biosynthetic process
CLM75_RS18310	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLM75_RS18315	COG0285	dihydrofolate synthase activity
CLM75_RS18320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLM75_RS18325	COG0135	phosphoribosylanthranilate isomerase activity
CLM75_RS18350	COG0473	3-isopropylmalate dehydrogenase activity
CLM75_RS18355	COG2226	methyltransferase
CLM75_RS18360	COG0066	3-isopropylmalate dehydratase activity
CLM75_RS18365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLM75_RS18395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLM75_RS18405	COG0596	Alpha beta hydrolase
CLM75_RS18435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM75_RS18440	COG0556	nucleotide-excision repair
CLM75_RS18455	COG0583	DNA-binding transcription factor activity
CLM75_RS18460	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS18470	COG2814	Major facilitator Superfamily
CLM75_RS18485	COG3591	Belongs to the peptidase S1B family
CLM75_RS18485	COG1864	DNA RNA non-specific endonuclease
CLM75_RS18495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CLM75_RS18500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM75_RS18505	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLM75_RS18520	COG0456	acetyltransferase
CLM75_RS18520	COG0454	-acetyltransferase
CLM75_RS18530	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CLM75_RS18560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS18570	COG1280	lysine exporter protein (LysE YggA)
CLM75_RS18595	COG0840	transmembrane signaling receptor activity
CLM75_RS18600	COG2384	SAM-dependent methyltransferase
CLM75_RS18605	COG2186	Transcriptional regulator
CLM75_RS18620	COG4521	taurine ABC transporter
CLM75_RS18630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLM75_RS18650	COG5285	phytanoyl-CoA dioxygenase
CLM75_RS18655	COG1126	abc transporter atp-binding protein
CLM75_RS18660	COG0583	DNA-binding transcription factor activity
CLM75_RS18675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLM75_RS18685	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLM75_RS18700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS18705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLM75_RS18715	COG2391	methyltransferase activity
CLM75_RS18740	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CLM75_RS18755	COG1309	transcriptional regulator
CLM75_RS18770	COG0640	Transcriptional regulator
CLM75_RS18810	COG2831	hemolysin activation secretion protein
CLM75_RS18825	COG0583	DNA-binding transcription factor activity
CLM75_RS18830	COG1304	FMN binding
CLM75_RS18845	COG5001	Diguanylate cyclase
CLM75_RS18845	COG5002	protein histidine kinase activity
CLM75_RS18860	COG1054	Belongs to the UPF0176 family
CLM75_RS18865	COG0271	Belongs to the BolA IbaG family
CLM75_RS18875	COG0114	fumarate hydratase activity
CLM75_RS18880	COG0697	spore germination
CLM75_RS18885	COG0183	Belongs to the thiolase family
CLM75_RS18890	COG2326	polyphosphate kinase activity
CLM75_RS18895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CLM75_RS18895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS18905	COG0367	asparagine synthase
CLM75_RS18910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLM75_RS18910	COG0189	ligase activity
CLM75_RS18915	COG1363	Peptidase, m42
CLM75_RS18920	COG3089	Belongs to the UPF0270 family
CLM75_RS18925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLM75_RS18940	COG1368	sulfuric ester hydrolase activity
CLM75_RS18960	COG0318	PFAM AMP-dependent synthetase and ligase
CLM75_RS18970	COG2197	response regulator
CLM75_RS18975	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CLM75_RS18985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLM75_RS18990	COG1073	alpha beta
CLM75_RS19015	COG2840	Smr protein MutS2
CLM75_RS19020	COG0302	gtp cyclohydrolase
CLM75_RS19040	COG2851	Citrate transporter
CLM75_RS19045	COG0583	DNA-binding transcription factor activity
CLM75_RS19050	COG0625	glutathione transferase activity
CLM75_RS19055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS19065	COG2252	PERMEase
CLM75_RS19095	COG4266	Belongs to the allantoicase family
CLM75_RS19100	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CLM75_RS19110	COG2233	PERMEase
CLM75_RS19125	COG1560	Kdo2-lipid A biosynthetic process
CLM75_RS19130	COG0850	regulation of cytokinetic process
CLM75_RS19135	COG2894	cell division
CLM75_RS19140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLM75_RS19145	COG0564	pseudouridine synthase activity
CLM75_RS19155	COG1362	aminopeptidase activity
CLM75_RS19160	COG0668	transmembrane transport
CLM75_RS19195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLM75_RS19225	COG1309	transcriptional regulator
CLM75_RS19240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CLM75_RS19245	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS19250	COG1024	Enoyl-CoA hydratase
CLM75_RS19265	COG3123	guanosine phosphorylase activity
CLM75_RS19270	COG0633	Ferredoxin
CLM75_RS19270	COG3217	Mosc domain protein beta barrel domain protein
CLM75_RS19290	COG2197	response regulator
CLM75_RS19295	COG1597	lipid kinase activity
CLM75_RS19310	COG0835	chemotaxis
CLM75_RS19320	COG1192	Involved in chromosome partitioning
CLM75_RS19325	COG1360	Flagellar Motor Protein
CLM75_RS19330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CLM75_RS19335	COG2201	protein-glutamate methylesterase activity
CLM75_RS19340	COG2198	Histidine kinase
CLM75_RS19340	COG0784	Response regulator, receiver
CLM75_RS19340	COG0643	Histidine kinase
CLM75_RS19345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CLM75_RS19375	COG1278	Cold shock
CLM75_RS19390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLM75_RS19445	COG0745	RESPONSE REGULATOR receiver
CLM75_RS19480	COG1677	Flagellar hook-basal body complex protein FliE
CLM75_RS19525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLM75_RS19545	COG1706	bacterial-type flagellum-dependent cell motility
CLM75_RS19550	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CLM75_RS19560	COG4787	bacterial-type flagellum-dependent cell motility
CLM75_RS19565	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CLM75_RS19575	COG2154	pterin-4-alpha-carbinolamine dehydratase
CLM75_RS19590	COG2207	Transcriptional regulator
CLM75_RS19610	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLM75_RS19615	COG1846	Transcriptional regulator
CLM75_RS19620	COG0514	ATP-dependent DNA helicase (RecQ)
CLM75_RS19630	COG2832	Protein of unknown function (DUF454)
CLM75_RS19635	COG2205	protein histidine kinase activity
CLM75_RS19635	COG0784	Response regulator, receiver
CLM75_RS19635	COG2198	Histidine kinase
CLM75_RS19690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CLM75_RS19695	COG0406	alpha-ribazole phosphatase activity
CLM75_RS19700	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CLM75_RS19710	COG1492	cobalamin metabolic process
CLM75_RS19720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CLM75_RS19725	COG0778	Nitroreductase
CLM75_RS19730	COG1797	cobyrinic acid a,c-diamide synthase activity
CLM75_RS19745	COG0791	NLP P60 protein
CLM75_RS19750	COG0791	NLP P60 protein
CLM75_RS19755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLM75_RS19760	COG0628	permease
CLM75_RS19770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLM75_RS19775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLM75_RS19790	COG3122	Protein conserved in bacteria
CLM75_RS19795	COG3956	TIGRFAM MazG family protein
CLM75_RS19800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLM75_RS19805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLM75_RS19840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLM75_RS19860	COG0583	DNA-binding transcription factor activity
CLM75_RS19870	COG1953	Uracil, thiamine, allantoin
CLM75_RS19880	COG2996	Protein conserved in bacteria
CLM75_RS19910	COG0513	Belongs to the DEAD box helicase family
CLM75_RS19915	COG0668	transmembrane transport
CLM75_RS19925	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLM75_RS19950	COG1132	(ABC) transporter
CLM75_RS19960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLM75_RS19980	COG2188	Transcriptional regulator
CLM75_RS19990	COG1595	DNA-templated transcription, initiation
CLM75_RS20000	COG1643	Atp-dependent helicase
CLM75_RS20010	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CLM75_RS20035	COG0840	transmembrane signaling receptor activity
CLM75_RS20045	COG3278	Belongs to the heme-copper respiratory oxidase family
CLM75_RS20065	COG3278	Belongs to the heme-copper respiratory oxidase family
CLM75_RS20080	COG2010	Cytochrome c
CLM75_RS20085	COG0348	domain, Protein
CLM75_RS20120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLM75_RS20125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLM75_RS20130	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS20135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLM75_RS20140	COG2130	NADP-dependent
CLM75_RS20145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLM75_RS20150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLM75_RS20170	COG0583	DNA-binding transcription factor activity
CLM75_RS20205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLM75_RS20210	COG3115	cell septum assembly
CLM75_RS20230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLM75_RS20240	COG0402	S-adenosylhomocysteine deaminase activity
CLM75_RS20245	COG1802	Transcriptional regulator
CLM75_RS20250	COG3135	benzoate transporter
CLM75_RS20255	COG3171	Protein conserved in bacteria
CLM75_RS20270	COG0116	Belongs to the methyltransferase superfamily
CLM75_RS20270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLM75_RS20275	COG3130	regulation of translation
CLM75_RS20280	COG0167	dihydroorotate dehydrogenase activity
CLM75_RS20300	COG1116	anion transmembrane transporter activity
CLM75_RS20300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM75_RS20305	COG3707	response regulator
CLM75_RS20310	COG2223	nitrite transmembrane transporter activity
CLM75_RS20320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLM75_RS20325	COG2885	chlorophyll binding
CLM75_RS20325	COG3047	cAMP biosynthetic process
CLM75_RS20350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLM75_RS20365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CLM75_RS20370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS20385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLM75_RS20390	COG1045	serine acetyltransferase
CLM75_RS20395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLM75_RS20400	COG2079	MmgE PrpD family protein
CLM75_RS20415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLM75_RS20420	COG0372	Belongs to the citrate synthase family
CLM75_RS20430	COG1802	Transcriptional regulator
CLM75_RS20435	COG4067	protein conserved in archaea
CLM75_RS20435	COG0189	ligase activity
CLM75_RS20445	COG0189	ligase activity
CLM75_RS20455	COG0560	Phosphoserine phosphatase
CLM75_RS20465	COG1953	Uracil, thiamine, allantoin
CLM75_RS20475	COG0583	DNA-binding transcription factor activity
CLM75_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS20485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLM75_RS20545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLM75_RS20565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLM75_RS20590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLM75_RS20635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLM75_RS20640	COG1074	ATP-dependent DNA helicase activity
CLM75_RS20645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLM75_RS20660	COG2003	Belongs to the UPF0758 family
CLM75_RS20680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLM75_RS20700	COG4983	Phage plasmid primase, P4 family domain protein
CLM75_RS20720	COG0598	Magnesium transport protein CorA
CLM75_RS20725	COG0519	Catalyzes the synthesis of GMP from XMP
CLM75_RS20725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM75_RS20730	COG1024	Enoyl-CoA hydratase
CLM75_RS20730	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM75_RS20735	COG0183	Belongs to the thiolase family
CLM75_RS20745	COG1305	Transglutaminase-like
CLM75_RS20755	COG2308	Evidence 4 Homologs of previously reported genes of
CLM75_RS20785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS20790	COG2885	chlorophyll binding
CLM75_RS20825	COG2207	Transcriptional regulator
CLM75_RS20830	COG1064	alcohol dehydrogenase
CLM75_RS20835	COG1414	Transcriptional regulator
CLM75_RS20840	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLM75_RS20845	COG1129	ABC transporter
CLM75_RS20850	COG1879	ABC-type sugar transport system periplasmic component
CLM75_RS20855	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS20895	COG1397	ADP-ribosylglycohydrolase
CLM75_RS20900	COG2188	Transcriptional regulator
CLM75_RS20915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLM75_RS20925	COG0084	hydrolase, TatD family'
CLM75_RS20935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLM75_RS20940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLM75_RS20950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLM75_RS20955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLM75_RS20970	COG0416	fatty acid biosynthetic process
CLM75_RS20975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLM75_RS20980	COG1399	metal-binding, possibly nucleic acid-binding protein
CLM75_RS20985	COG0424	maF-like protein
CLM75_RS20990	COG0616	signal peptide processing
CLM75_RS20990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLM75_RS20995	COG0546	phosphoglycolate phosphatase activity
CLM75_RS21010	COG1530	ribonuclease E activity
CLM75_RS21020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CLM75_RS21020	COG3608	succinylglutamate desuccinylase aspartoacylase
CLM75_RS21025	COG1301	dicarboxylic acid transport
CLM75_RS21030	COG1917	Cupin 2, conserved barrel domain protein
CLM75_RS21030	COG4977	sequence-specific DNA binding
CLM75_RS21050	COG2977	Belongs to the P-Pant transferase superfamily
CLM75_RS21055	COG2205	protein histidine kinase activity
CLM75_RS21060	COG0745	RESPONSE REGULATOR receiver
CLM75_RS21075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CLM75_RS21080	COG1558	bacterial-type flagellum-dependent cell motility
CLM75_RS21085	COG1815	bacterial-type flagellum-dependent cell motility
CLM75_RS21090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLM75_RS21095	COG0835	chemotaxis
CLM75_RS21095	COG0784	Response regulator, receiver
CLM75_RS21115	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CLM75_RS21120	COG0477	Major facilitator Superfamily
CLM75_RS21145	COG2239	Acts as a magnesium transporter
CLM75_RS21165	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLM75_RS21170	COG0527	aspartate kinase activity
CLM75_RS21175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLM75_RS21180	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CLM75_RS21185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLM75_RS21195	COG2988	succinylglutamate desuccinylase activity
CLM75_RS21205	COG3724	N-succinylarginine dihydrolase activity
CLM75_RS21210	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS21225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM75_RS21260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS21265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM75_RS21275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLM75_RS21300	COG0165	Argininosuccinate lyase
CLM75_RS21305	COG0765	amino acid transport
CLM75_RS21320	COG2814	Major facilitator Superfamily
CLM75_RS21335	COG0154	amidase activity
CLM75_RS21355	COG3706	GGDEF domain
CLM75_RS21375	COG0504	CTP synthase activity
CLM75_RS21380	COG2329	Antibiotic biosynthesis monooxygenase
CLM75_RS21390	COG0584	glycerophosphoryl diester phosphodiesterase
CLM75_RS21420	COG0306	phosphate transporter
CLM75_RS21425	COG1984	allophanate hydrolase subunit 2
CLM75_RS21435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLM75_RS21445	COG0583	DNA-binding transcription factor activity
CLM75_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS21465	COG0583	DNA-binding transcription factor activity
CLM75_RS21470	COG0583	DNA-binding transcription factor activity
CLM75_RS21475	COG4221	oxidoreductase activity
CLM75_RS21480	COG4941	Belongs to the sigma-70 factor family
CLM75_RS21490	COG3795	YCII-related domain
CLM75_RS21515	COG0436	Aminotransferase
CLM75_RS21525	COG3265	gluconokinase activity
CLM75_RS21530	COG1609	Transcriptional regulator
CLM75_RS21545	COG2271	Major facilitator Superfamily
CLM75_RS21580	COG0242	peptide deformylase activity
CLM75_RS21585	COG1295	ribonuclease BN
CLM75_RS21605	COG0318	PFAM AMP-dependent synthetase and ligase
CLM75_RS21615	COG2030	dehydratase
CLM75_RS21625	COG3530	Putative quorum-sensing-regulated virulence factor
CLM75_RS21630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLM75_RS21635	COG0800	Aldolase
CLM75_RS21650	COG1737	Transcriptional regulator
CLM75_RS21655	COG0676	glucose-6-phosphate 1-epimerase activity
CLM75_RS21665	COG3842	ATPase activity
CLM75_RS21670	COG0395	ABC-type sugar transport system, permease component
CLM75_RS21675	COG1175	transmembrane transport
CLM75_RS21680	COG1653	transport
CLM75_RS21685	COG2942	2-epimerase
CLM75_RS21700	COG0583	DNA-binding transcription factor activity
CLM75_RS21715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLM75_RS21735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLM75_RS21765	COG1113	amino acid transport
CLM75_RS21785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLM75_RS21795	COG0009	L-threonylcarbamoyladenylate synthase
CLM75_RS21800	COG0613	PHP domain protein
CLM75_RS21805	COG2917	probably involved in intracellular septation
CLM75_RS21810	COG2350	Protein conserved in bacteria
CLM75_RS21820	COG0745	RESPONSE REGULATOR receiver
CLM75_RS21830	COG0642	Histidine kinase
CLM75_RS21885	COG0509	glycine decarboxylation via glycine cleavage system
CLM75_RS21890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLM75_RS21890	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLM75_RS21895	COG1760	l-serine dehydratase
CLM75_RS21900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLM75_RS21905	COG1278	Cold shock
CLM75_RS21915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLM75_RS21935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLM75_RS21940	COG0602	queuosine metabolic process
CLM75_RS21945	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CLM75_RS21950	COG2885	chlorophyll binding
CLM75_RS21955	COG0823	Involved in the tonB-independent uptake of proteins
CLM75_RS21975	COG0824	Thioesterase
CLM75_RS21980	COG2255	four-way junction helicase activity
CLM75_RS21985	COG0632	four-way junction helicase activity
CLM75_RS21990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLM75_RS21995	COG0217	transcriptional regulatory protein
CLM75_RS22000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLM75_RS22015	COG0783	Belongs to the Dps family
CLM75_RS22025	COG2900	Belongs to the SlyX family
CLM75_RS22040	COG0668	transmembrane transport
CLM75_RS22045	COG1666	GTP binding
CLM75_RS22055	COG4191	Histidine kinase
CLM75_RS22055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS22060	COG2096	Adenosyltransferase
CLM75_RS22070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLM75_RS22075	COG0653	protein targeting
CLM75_RS22085	COG0433	COG0433 Predicted ATPase
CLM75_RS22095	COG0788	formyltetrahydrofolate deformylase activity
CLM75_RS22105	COG2925	Exonuclease
CLM75_RS22130	COG0714	Associated with various cellular activities
CLM75_RS22150	COG0469	pyruvate kinase activity
CLM75_RS22155	COG1024	Enoyl-CoA hydratase
CLM75_RS22170	COG4191	Histidine kinase
CLM75_RS22180	COG0477	Major facilitator Superfamily
CLM75_RS22205	COG2207	Transcriptional regulator
CLM75_RS22235	COG1595	DNA-templated transcription, initiation
CLM75_RS22240	COG3712	iron ion homeostasis
CLM75_RS22245	COG4771	TonB-dependent receptor
CLM75_RS22255	COG2832	Protein of unknown function (DUF454)
CLM75_RS22260	COG0840	transmembrane signaling receptor activity
CLM75_RS22285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS22290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLM75_RS22300	COG3642	lipopolysaccharide core region biosynthetic process
CLM75_RS22310	COG0642	Histidine kinase
CLM75_RS22320	COG0459	protein refolding
CLM75_RS22325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLM75_RS22350	COG2211	Major facilitator Superfamily
CLM75_RS22355	COG0442	prolyl-tRNA aminoacylation
CLM75_RS22365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLM75_RS22400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CLM75_RS22430	COG4974	Belongs to the 'phage' integrase family
CLM75_RS22435	COG1607	acyl-coa hydrolase
CLM75_RS22440	COG0335	large ribosomal subunit rRNA binding
CLM75_RS22445	COG0336	Belongs to the RNA methyltransferase TrmD family
CLM75_RS22450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLM75_RS22455	COG0228	four-way junction DNA binding
CLM75_RS22460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLM75_RS22470	COG4536	flavin adenine dinucleotide binding
CLM75_RS22475	COG0477	Major facilitator Superfamily
CLM75_RS22480	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLM75_RS22500	COG0494	nUDIX hydrolase
CLM75_RS22515	COG2188	Transcriptional regulator
CLM75_RS22520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLM75_RS22525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLM75_RS22530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLM75_RS22530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLM75_RS22535	COG2190	(PTS) system
CLM75_RS22535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLM75_RS22535	COG1263	PTS System
CLM75_RS22540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLM75_RS22545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLM75_RS22545	COG0047	phosphoribosylformylglycinamidine synthase activity
CLM75_RS22550	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CLM75_RS22560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLM75_RS22560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLM75_RS22565	COG4580	involved in the transport of maltose and maltodextrins
CLM75_RS22570	COG0366	Alpha amylase catalytic
CLM75_RS22575	COG1263	PTS System
CLM75_RS22575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLM75_RS22580	COG2188	Transcriptional regulator
CLM75_RS22590	COG0519	Catalyzes the synthesis of GMP from XMP
CLM75_RS22590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLM75_RS22610	COG0583	DNA-binding transcription factor activity
CLM75_RS22615	COG1570	exodeoxyribonuclease VII activity
CLM75_RS22620	COG0739	heme binding
CLM75_RS22630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLM75_RS22635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS22640	COG0436	Aminotransferase
CLM75_RS22645	COG1160	GTP binding
CLM75_RS22660	COG0124	histidyl-tRNA synthetase
CLM75_RS22665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLM75_RS22670	COG1426	Protein conserved in bacteria
CLM75_RS22680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CLM75_RS22685	COG0105	UTP biosynthetic process
CLM75_RS22695	COG0633	Ferredoxin
CLM75_RS22700	COG0443	Heat shock 70 kDa protein
CLM75_RS22705	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLM75_RS22710	COG0316	Belongs to the HesB IscA family
CLM75_RS22720	COG1104	cysteine desulfurase activity
CLM75_RS22730	COG1045	serine acetyltransferase
CLM75_RS22745	COG3134	Outer membrane lipoprotein
CLM75_RS22760	COG1862	Preprotein translocase
CLM75_RS22765	COG0343	queuine tRNA-ribosyltransferase activity
CLM75_RS22770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLM75_RS22890	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CLM75_RS22915	COG1280	lysine exporter protein (LysE YggA)
CLM75_RS22925	COG1569	PIN domain
CLM75_RS22930	COG3311	Transcriptional regulator
CLM75_RS22955	COG0642	Histidine kinase
CLM75_RS23005	COG4251	negative regulation of phosphorylation
CLM75_RS23025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS23030	COG0583	DNA-binding transcription factor activity
CLM75_RS23035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLM75_RS23050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLM75_RS23055	COG0109	protoheme IX farnesyltransferase activity
CLM75_RS23065	COG1845	cytochrome c oxidase, subunit III
CLM75_RS23070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLM75_RS23075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLM75_RS23085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLM75_RS23090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLM75_RS23090	COG1017	nitric oxide dioxygenase activity
CLM75_RS23095	COG3604	Transcriptional regulator
CLM75_RS23105	COG2207	Transcriptional regulator
CLM75_RS23105	COG3708	Transcriptional regulator
CLM75_RS23110	COG2909	trisaccharide binding
CLM75_RS23125	COG1028	Short-chain dehydrogenase reductase Sdr
CLM75_RS23140	COG1346	cytolysis
CLM75_RS23145	COG1380	Effector of murein hydrolase LrgA
CLM75_RS23150	COG0583	DNA-binding transcription factor activity
CLM75_RS23160	COG1366	Belongs to the anti-sigma-factor antagonist family
CLM75_RS23185	COG0302	gtp cyclohydrolase
CLM75_RS23190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLM75_RS23205	COG0492	ferredoxin-NADP+ reductase activity
CLM75_RS23210	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CLM75_RS23225	COG0386	Belongs to the glutathione peroxidase family
CLM75_RS23230	COG3045	CreA protein
CLM75_RS23235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLM75_RS23240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLM75_RS23245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CLM75_RS23250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CLM75_RS23255	COG0142	geranyltranstransferase activity
CLM75_RS23260	COG2824	Alkylphosphonate utilization operon protein PhnA
CLM75_RS23265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLM75_RS23270	COG0545	Peptidyl-prolyl cis-trans isomerase
CLM75_RS23275	COG0840	transmembrane signaling receptor activity
CLM75_RS23285	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CLM75_RS23295	COG2610	gluconate transmembrane transporter activity
CLM75_RS23305	COG0659	secondary active sulfate transmembrane transporter activity
CLM75_RS23315	COG0583	DNA-binding transcription factor activity
CLM75_RS23320	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM75_RS23330	COG0583	DNA-binding transcription factor activity
CLM75_RS23335	COG1113	amino acid transport
CLM75_RS23345	COG1522	sequence-specific DNA binding
CLM75_RS23350	COG3485	protocatechuate 3,4-dioxygenase
CLM75_RS23355	COG4829	muconolactone delta-isomerase
CLM75_RS23360	COG4948	Mandelate Racemase Muconate Lactonizing
CLM75_RS23375	COG4638	Rieske (2fe-2S)
CLM75_RS23380	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CLM75_RS23385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLM75_RS23385	COG0543	2 iron, 2 sulfur cluster binding
CLM75_RS23390	COG1113	amino acid transport
CLM75_RS23395	COG3483	tryptophan 2,3-dioxygenase activity
CLM75_RS23400	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CLM75_RS23440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLM75_RS23445	COG1074	ATP-dependent DNA helicase activity
CLM75_RS23450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLM75_RS23485	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CLM75_RS23490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLM75_RS23495	COG1183	phosphatidylcholine synthase activity
CLM75_RS23500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLM75_RS23510	COG0028	Belongs to the TPP enzyme family
CLM75_RS23515	COG3098	single-species biofilm formation
CLM75_RS23525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLM75_RS23545	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLM75_RS23550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLM75_RS23555	COG4558	Periplasmic binding protein
CLM75_RS23565	COG1489	DNA binding
CLM75_RS23570	COG0436	Aminotransferase
CLM75_RS23580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLM75_RS23590	COG4191	Histidine kinase
CLM75_RS23605	COG0617	tRNA 3'-terminal CCA addition
CLM75_RS23615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLM75_RS23620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLM75_RS23625	COG0166	Belongs to the GPI family
CLM75_RS23630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLM75_RS23640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLM75_RS23650	COG2823	Periplasmic or secreted lipoprotein
CLM75_RS23655	COG1185	polyribonucleotide nucleotidyltransferase activity
CLM75_RS23660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLM75_RS23665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLM75_RS23670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLM75_RS23675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLM75_RS23680	COG0195	Participates in both transcription termination and antitermination
CLM75_RS23685	COG0779	Required for maturation of 30S ribosomal subunits
CLM75_RS23700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLM75_RS23705	COG0149	triose-phosphate isomerase activity
CLM75_RS23710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLM75_RS23715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLM75_RS23725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CLM75_RS23740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM75_RS23745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLM75_RS23750	COG0505	Belongs to the CarA family
CLM75_RS23755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CLM75_RS23760	COG0484	heat shock protein binding
CLM75_RS23765	COG0443	Heat shock 70 kDa protein
CLM75_RS23770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLM75_RS23775	COG0497	DNA recombination
CLM75_RS23780	COG0735	belongs to the Fur family
CLM75_RS23785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLM75_RS23790	COG2914	Belongs to the UPF0125 (RnfH) family
CLM75_RS23800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLM75_RS23805	COG2186	Transcriptional regulator
CLM75_RS23810	COG1620	l-lactate permease
CLM75_RS23880	COG3179	chitinase
CLM75_RS23965	COG0582	viral genome integration into host DNA
CLM75_RS23990	COG2862	Uncharacterized protein family, UPF0114
CLM75_RS24005	COG1067	ATP-dependent peptidase activity
CLM75_RS24025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM75_RS24035	COG0488	(ABC) transporter
CLM75_RS24050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLM75_RS24055	COG0523	cobalamin synthesis protein
CLM75_RS24060	COG2879	small protein
CLM75_RS24065	COG1966	Carbon starvation protein
CLM75_RS24090	COG1970	mechanosensitive ion channel activity
CLM75_RS24100	COG2197	response regulator
CLM75_RS24105	COG2813	Specifically methylates the guanine in position
CLM75_RS24115	COG1294	oxidase, subunit
CLM75_RS24120	COG1271	oxidase subunit
CLM75_RS24130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CLM75_RS24135	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CLM75_RS24140	COG2080	2 iron, 2 sulfur cluster binding
CLM75_RS24150	COG2252	PERMEase
CLM75_RS24155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLM75_RS24185	COG1629	transport
CLM75_RS24185	COG4206	TonB-dependent receptor
CLM75_RS24205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CLM75_RS24210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLM75_RS24215	COG1309	transcriptional regulator
CLM75_RS24220	COG1082	Xylose isomerase domain protein TIM barrel
CLM75_RS24220	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CLM75_RS24225	COG0477	Major facilitator Superfamily
CLM75_RS24240	COG2321	neutral zinc metallopeptidase
CLM75_RS24255	COG1946	Acyl-CoA thioesterase
CLM75_RS24265	COG0123	including yeast histone deacetylase and acetoin utilization protein
CLM75_RS24275	COG0513	Belongs to the DEAD box helicase family
CLM75_RS24280	COG0697	spore germination
CLM75_RS24285	COG1522	sequence-specific DNA binding
CLM75_RS24290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLM75_RS24290	COG1199	ATP-dependent helicase activity
CLM75_RS24300	COG3416	Protein conserved in bacteria
CLM75_RS24315	COG1643	Atp-dependent helicase
CLM75_RS24325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLM75_RS24335	COG1522	sequence-specific DNA binding
CLM75_RS24350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLM75_RS24355	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS24360	COG2205	protein histidine kinase activity
CLM75_RS24360	COG0784	Response regulator, receiver
CLM75_RS24360	COG2198	Histidine kinase
CLM75_RS24370	COG0352	thiamine-phosphate diphosphorylase activity
CLM75_RS24375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLM75_RS24390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLM75_RS24395	COG1702	phosphate starvation-inducible protein PhoH
CLM75_RS24400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLM75_RS24405	COG4535	Mg2 and Co2 transporter CorC
CLM75_RS24410	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLM75_RS24425	COG0495	leucyl-tRNA aminoacylation
CLM75_RS24435	COG1466	dna polymerase III delta subunit
CLM75_RS24445	COG2951	lytic endotransglycosylase activity
CLM75_RS24455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLM75_RS24460	COG0321	lipoyl(octanoyl) transferase activity
CLM75_RS24465	COG2921	Belongs to the UPF0250 family
CLM75_RS24470	COG1686	Belongs to the peptidase S11 family
CLM75_RS24480	COG2951	lytic endotransglycosylase activity
CLM75_RS24485	COG0772	Belongs to the SEDS family
CLM75_RS24490	COG0768	penicillin binding
CLM75_RS24495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLM75_RS24505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLM75_RS24510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLM75_RS24515	COG2094	Belongs to the DNA glycosylase MPG family
CLM75_RS24520	COG0586	Pfam SNARE associated Golgi protein
CLM75_RS24530	COG1346	cytolysis
CLM75_RS24555	COG0702	epimerase
CLM75_RS24570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLM75_RS24575	COG3284	Transcriptional regulator
CLM75_RS24585	COG0531	amino acid
CLM75_RS24590	COG4303	Ethanolamine ammonia lyase large subunit
CLM75_RS24595	COG4302	ethanolamine ammonia-lyase activity
CLM75_RS24600	COG0456	acetyltransferase
CLM75_RS24605	COG0586	Pfam SNARE associated Golgi protein
CLM75_RS24610	COG3228	Belongs to the MtfA family
CLM75_RS24615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLM75_RS24630	COG0754	glutathionylspermidine amidase activity
CLM75_RS24640	COG3766	membrane
CLM75_RS24660	COG1842	Phage shock protein A
CLM75_RS24670	COG1335	isochorismatase
CLM75_RS24680	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLM75_RS24690	COG1722	exodeoxyribonuclease VII activity
CLM75_RS24695	COG0142	geranyltranstransferase activity
CLM75_RS24700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLM75_RS24705	COG4206	TonB-dependent receptor
CLM75_RS24720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLM75_RS24730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLM75_RS24735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLM75_RS24740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLM75_RS24755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLM75_RS24755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLM75_RS24760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLM75_RS24770	COG2264	protein methyltransferase activity
CLM75_RS24775	COG3118	belongs to the thioredoxin family
CLM75_RS24790	COG4181	ATPase activity
CLM75_RS24815	COG1201	RNA secondary structure unwinding
CLM75_RS24820	COG0668	transmembrane transport
CLM75_RS24825	COG2814	Major facilitator Superfamily
CLM75_RS24830	COG3568	Endonuclease Exonuclease Phosphatase
CLM75_RS24835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM75_RS24840	COG0392	lysyltransferase activity
CLM75_RS24860	COG1335	isochorismatase
CLM75_RS24865	COG4106	trans-aconitate 2-methyltransferase activity
CLM75_RS24870	COG0583	DNA-binding transcription factor activity
CLM75_RS24875	COG0326	Molecular chaperone. Has ATPase activity
CLM75_RS24905	COG0629	single-stranded DNA binding
CLM75_RS24910	COG2814	Major facilitator Superfamily
CLM75_RS24915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLM75_RS24920	COG2193	ferroxidase activity
CLM75_RS24930	COG0203	ribosomal protein L17
CLM75_RS24935	COG0202	RNA polymerase activity
CLM75_RS24940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLM75_RS24945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLM75_RS24950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLM75_RS24955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLM75_RS24965	COG0200	Binds to the 23S rRNA
CLM75_RS24970	COG1841	ribosomal large subunit assembly
CLM75_RS24975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLM75_RS24980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLM75_RS24985	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLM75_RS24990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLM75_RS24995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLM75_RS25000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLM75_RS25005	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLM75_RS25010	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLM75_RS25015	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLM75_RS25020	COG0255	Belongs to the universal ribosomal protein uL29 family
CLM75_RS25025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLM75_RS25030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLM75_RS25035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLM75_RS25040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLM75_RS25045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLM75_RS25050	COG0089	rRNA binding
CLM75_RS25055	COG0088	Forms part of the polypeptide exit tunnel
CLM75_RS25060	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLM75_RS25065	COG0051	transcription antitermination factor activity, RNA binding
CLM75_RS25070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLM75_RS25075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLM75_RS25080	COG0049	tRNA binding
CLM75_RS25085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLM75_RS25090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLM75_RS25095	COG0085	RNA polymerase activity
CLM75_RS25100	COG0222	ribosome binding
CLM75_RS25105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLM75_RS25110	COG0081	regulation of translation
CLM75_RS25115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLM75_RS25155	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CLM75_RS25195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLM75_RS25200	COG0739	heme binding
CLM75_RS25205	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CLM75_RS25210	COG0316	Belongs to the HesB IscA family
CLM75_RS25215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLM75_RS25220	COG1981	membrane
CLM75_RS25240	COG0537	adenosine 5'-monophosphoramidase activity
CLM75_RS25245	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CLM75_RS25250	COG1765	OsmC-like protein
CLM75_RS25265	COG0134	indole-3-glycerol-phosphate synthase activity
CLM75_RS25270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLM75_RS25275	COG0512	Glutamine amidotransferase of anthranilate synthase
CLM75_RS25280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLM75_RS25285	COG0546	phosphoglycolate phosphatase activity
CLM75_RS25290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLM75_RS25295	COG1454	alcohol dehydrogenase
CLM75_RS25305	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM75_RS25315	COG3842	ATPase activity
CLM75_RS25320	COG2197	response regulator
CLM75_RS25335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CLM75_RS25340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLM75_RS25345	COG3178	'Phosphotransferase
CLM75_RS25350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLM75_RS25355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLM75_RS25360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLM75_RS25365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLM75_RS25370	COG2967	ApaG domain
CLM75_RS25375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CLM75_RS25380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLM75_RS25385	COG2766	serine protein kinase
CLM75_RS25390	COG2718	Belongs to the UPF0229 family
CLM75_RS25395	COG2719	SpoVR family
CLM75_RS25400	COG0617	tRNA 3'-terminal CCA addition
CLM75_RS25410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLM75_RS25415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CLM75_RS25420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLM75_RS25425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLM75_RS25430	COG0358	DNA primase activity
CLM75_RS25435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLM75_RS25455	COG0583	DNA-binding transcription factor activity
CLM75_RS25470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLM75_RS25475	COG1025	Belongs to the peptidase M16 family
CLM75_RS25485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLM75_RS25490	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CLM75_RS25500	COG0535	radical SAM domain protein
CLM75_RS25510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLM75_RS25515	COG0583	DNA-binding transcription factor activity
CLM75_RS25520	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS25525	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS25535	COG1960	acyl-CoA dehydrogenase activity
CLM75_RS25555	COG1073	alpha beta
CLM75_RS25555	COG2226	methyltransferase
CLM75_RS25560	COG0156	8-amino-7-oxononanoate synthase activity
CLM75_RS25565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLM75_RS25575	COG3585	molybdate ion transport
CLM75_RS25575	COG2005	Transcriptional regulator
CLM75_RS25585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLM75_RS25600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLM75_RS25605	COG4566	intracellular signal transduction
CLM75_RS25605	COG0745	RESPONSE REGULATOR receiver
CLM75_RS25620	COG1595	DNA-templated transcription, initiation
CLM75_RS25630	COG4774	siderophore transport
CLM75_RS25645	COG4452	Inner membrane protein CreD
CLM75_RS25650	COG2205	protein histidine kinase activity
CLM75_RS25655	COG0745	RESPONSE REGULATOR receiver
CLM75_RS25660	COG0189	ligase activity
CLM75_RS25660	COG4067	protein conserved in archaea
CLM75_RS25665	COG0204	Acyl-transferase
CLM75_RS25675	COG1595	DNA-templated transcription, initiation
CLM75_RS25690	COG1063	alcohol dehydrogenase
CLM75_RS25720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLM75_RS25740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLM75_RS25740	COG1017	nitric oxide dioxygenase activity
CLM75_RS25750	COG4638	Rieske (2fe-2S)
CLM75_RS25760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CLM75_RS25765	COG2181	nitrate reductase activity
CLM75_RS25765	COG0247	lactate metabolic process
CLM75_RS25770	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLM75_RS25770	COG1902	pentaerythritol trinitrate reductase activity
CLM75_RS25810	COG3246	L-lysine catabolic process to acetate
CLM75_RS25815	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLM75_RS25840	COG1760	l-serine dehydratase
CLM75_RS25855	COG4175	Glycine betaine
CLM75_RS25860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CLM75_RS25865	COG1309	transcriptional regulator
CLM75_RS25870	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS25875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLM75_RS25885	COG0312	modulator of DNA gyrase
CLM75_RS25895	COG0477	Major facilitator Superfamily
CLM75_RS25900	COG0513	Belongs to the DEAD box helicase family
CLM75_RS25905	COG2081	HI0933 family
CLM75_RS25910	COG1289	transmembrane transporter activity
CLM75_RS25920	COG2153	protein acetylation
CLM75_RS25930	COG1451	nucleotide metabolic process
CLM75_RS25960	COG0126	phosphoglycerate kinase activity
CLM75_RS25965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLM75_RS25970	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLM75_RS25975	COG0640	Transcriptional regulator
CLM75_RS25980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLM75_RS25990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLM75_RS25995	COG1422	Protein of unknown function (DUF1090)
CLM75_RS26020	COG2116	formate transmembrane transporter activity
CLM75_RS26035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CLM75_RS26040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CLM75_RS26055	COG0513	Belongs to the DEAD box helicase family
CLM75_RS26060	COG2353	YceI-like domain
CLM75_RS26065	COG3038	cytochrome b561
CLM75_RS26075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLM75_RS26080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS26100	COG1272	protein, Hemolysin III
CLM75_RS26130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLM75_RS26150	COG3052	prosthetic group binding
CLM75_RS26155	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CLM75_RS26185	COG3093	addiction module antidote protein HigA
CLM75_RS26195	COG0643	Histidine kinase
CLM75_RS26195	COG0784	Response regulator, receiver
CLM75_RS26195	COG2198	Histidine kinase
CLM75_RS26220	COG0189	ligase activity
CLM75_RS26230	COG1678	Uncharacterized ACR, COG1678
CLM75_RS26235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLM75_RS26240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLM75_RS26245	COG0540	Belongs to the ATCase OTCase family
CLM75_RS26250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLM75_RS26260	COG0791	NLP P60 protein
CLM75_RS26285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM75_RS26290	COG2813	Specifically methylates the guanine in position
CLM75_RS26290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLM75_RS26300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLM75_RS26305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLM75_RS26315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CLM75_RS26320	COG2022	thiamine diphosphate biosynthetic process
CLM75_RS26330	COG2363	Small membrane protein
CLM75_RS26335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLM75_RS26345	COG2177	Part of the ABC transporter FtsEX involved in
CLM75_RS26350	COG2884	Cell division ATP-binding protein ftsE
CLM75_RS26355	COG0552	protein localization to endoplasmic reticulum
CLM75_RS26360	COG0612	Peptidase, M16
CLM75_RS26365	COG0612	Peptidase, M16
CLM75_RS26370	COG0742	ribosomal rna small subunit methyltransferase
CLM75_RS26375	COG0429	hydrolase of the alpha beta-hydrolase fold
CLM75_RS26385	COG1309	transcriptional regulator
CLM75_RS26400	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLM75_RS26405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLM75_RS26410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLM75_RS26415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CLM75_RS26425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLM75_RS26430	COG2814	Major facilitator Superfamily
CLM75_RS26435	COG0129	dihydroxy-acid dehydratase activity
CLM75_RS26445	COG1823	symporter activity
CLM75_RS26460	COG1160	GTP binding
CLM75_RS26475	COG1840	ABC-type Fe3 transport system, periplasmic component
CLM75_RS26480	COG1178	ABC-type Fe3 transport system permease component
CLM75_RS26485	COG3842	ATPase activity
CLM75_RS26490	COG0583	DNA-binding transcription factor activity
CLM75_RS26500	COG0789	Transcriptional regulator
CLM75_RS26505	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLM75_RS26510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLM75_RS26515	COG0730	response to heat
CLM75_RS26530	COG0494	nUDIX hydrolase
CLM75_RS26545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLM75_RS26550	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLM75_RS26555	COG3204	pilus organization
CLM75_RS26560	COG3204	pilus organization
CLM75_RS26565	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLM75_RS26570	COG0277	FAD linked oxidase domain protein
CLM75_RS26580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLM75_RS26590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS26595	COG1683	Conserved Protein
CLM75_RS26625	COG1917	Cupin 2, conserved barrel domain protein
CLM75_RS26625	COG4977	sequence-specific DNA binding
CLM75_RS26630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLM75_RS26645	COG1177	transmembrane transport
CLM75_RS26650	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLM75_RS26655	COG3842	ATPase activity
CLM75_RS26675	COG0174	glutamine synthetase
CLM75_RS26680	COG0174	glutamine synthetase
CLM75_RS26695	COG1116	anion transmembrane transporter activity
CLM75_RS26700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CLM75_RS26705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLM75_RS26710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CLM75_RS26715	COG0431	NADPH-dependent FMN reductase
CLM75_RS26720	COG0450	alkyl hydroperoxide reductase
CLM75_RS26730	COG4521	taurine ABC transporter
CLM75_RS26735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLM75_RS26735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLM75_RS26750	COG1522	sequence-specific DNA binding
CLM75_RS26760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLM75_RS26765	COG0330	HflC and HflK could
CLM75_RS26780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLM75_RS26785	COG0509	glycine decarboxylation via glycine cleavage system
CLM75_RS26790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLM75_RS26795	COG1178	ABC-type Fe3 transport system permease component
CLM75_RS26805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM75_RS26815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLM75_RS26820	COG0006	proline dipeptidase activity
CLM75_RS26825	COG3079	Belongs to the UPF0149 family
CLM75_RS26845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLM75_RS26855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLM75_RS26860	COG1129	ABC transporter
CLM75_RS26860	COG0842	Transport permease protein
CLM75_RS26865	COG0842	Transport permease protein
CLM75_RS26880	COG2271	Major facilitator Superfamily
CLM75_RS26905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CLM75_RS26925	COG2186	Transcriptional regulator
CLM75_RS26930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLM75_RS26935	COG0765	amino acid transport
CLM75_RS26940	COG0765	amino acid transport
CLM75_RS26955	COG3188	usher protein
CLM75_RS26960	COG3121	Chaperone
CLM75_RS26970	COG0248	Ppx GppA phosphatase
CLM75_RS26975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLM75_RS26985	COG0586	Pfam SNARE associated Golgi protein
CLM75_RS26995	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CLM75_RS27000	COG1671	Belongs to the UPF0178 family
CLM75_RS27005	COG0672	)-iron permease
CLM75_RS27040	COG0488	(ABC) transporter
CLM75_RS27065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CLM75_RS27080	COG0181	hydroxymethylbilane synthase activity
CLM75_RS27090	COG0165	Argininosuccinate lyase
CLM75_RS27095	COG0625	glutathione transferase activity
CLM75_RS27115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLM75_RS27125	COG1965	Belongs to the frataxin family
CLM75_RS27135	COG0019	diaminopimelate decarboxylase activity
CLM75_RS27140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLM75_RS27150	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLM75_RS27155	COG1011	Hydrolase
CLM75_RS27165	COG0432	Pfam Uncharacterised protein family UPF0047
CLM75_RS27170	COG0004	ammonium transporteR
CLM75_RS27175	COG0347	Belongs to the P(II) protein family
CLM75_RS27190	COG0606	chelatase, subunit chli
CLM75_RS27195	COG0840	transmembrane signaling receptor activity
CLM75_RS27200	COG0583	DNA-binding transcription factor activity
CLM75_RS27205	COG0534	Mate efflux family protein
CLM75_RS27220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLM75_RS27225	COG0427	acetyl-CoA hydrolase
CLM75_RS27240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLM75_RS27245	COG0251	oxidation-reduction process
CLM75_RS27250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS27265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLM75_RS27275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLM75_RS27280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM75_RS27290	COG1012	belongs to the aldehyde dehydrogenase family
CLM75_RS27300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLM75_RS27305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLM75_RS27310	COG0747	negative chemotaxis
CLM75_RS27315	COG2003	Belongs to the UPF0758 family
CLM75_RS27320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLM75_RS27325	COG0756	dUTP diphosphatase activity
CLM75_RS27335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLM75_RS27340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLM75_RS27345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLM75_RS27350	COG0708	Exodeoxyribonuclease III
CLM75_RS27360	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLM75_RS27365	COG1561	YicC-like family, N-terminal region
CLM75_RS27370	COG0194	GDP metabolic process
CLM75_RS27375	COG1758	RNA polymerase activity
CLM75_RS27380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLM75_RS27405	COG0848	biopolymer transport protein
CLM75_RS27415	COG0583	DNA-binding transcription factor activity
CLM75_RS27420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLM75_RS27450	COG1136	(ABC) transporter
CLM75_RS27455	COG0515	serine threonine protein kinase
CLM75_RS27455	COG2815	serine threonine protein kinase
CLM75_RS27545	COG3209	COG3209 Rhs family protein
CLM75_RS27580	COG3161	chorismate lyase activity
CLM75_RS27585	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CLM75_RS27605	COG1253	flavin adenine dinucleotide binding
CLM75_RS27615	COG0704	Plays a role in the regulation of phosphate uptake
CLM75_RS27620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CLM75_RS27625	COG0573	inorganic phosphate transmembrane transporter activity
CLM75_RS27640	COG0477	Major facilitator Superfamily
CLM75_RS27645	COG1607	acyl-coa hydrolase
CLM75_RS27675	COG0583	DNA-binding transcription factor activity
CLM75_RS27680	COG1027	Aspartate ammonia-lyase
CLM75_RS27685	COG1115	amino acid carrier protein
CLM75_RS27690	COG0252	asparaginase activity
CLM75_RS27720	COG2808	Putative FMN-binding domain
CLM75_RS27740	COG5016	pyruvate
CLM75_RS27740	COG0511	ligase activity, forming carbon-carbon bonds
CLM75_RS27745	COG0439	Biotin carboxylase
CLM75_RS27750	COG0583	DNA-binding transcription factor activity
CLM75_RS27765	COG3300	MHYT domain
CLM75_RS27765	COG5001	Diguanylate cyclase
CLM75_RS27770	COG0210	DNA helicase
CLM75_RS27785	COG4651	solute:proton antiporter activity
CLM75_RS27785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLM75_RS27790	COG1607	acyl-coa hydrolase
CLM75_RS27800	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CLM75_RS27810	COG0523	cobalamin synthesis protein
CLM75_RS27835	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLM75_RS27840	COG1469	GTP cyclohydrolase I activity
CLM75_RS27845	COG1121	(ABC) transporter
CLM75_RS27860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLM75_RS27870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CLM75_RS27880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLM75_RS27885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLM75_RS27895	COG3220	belongs to the UPF0276 family
CLM75_RS27925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLM75_RS27930	COG2267	carboxylic ester hydrolase activity
CLM75_RS27935	COG0671	phosphoesterase, PA-phosphatase related
CLM75_RS27935	COG2453	phosphatase
CLM75_RS27950	COG4589	Belongs to the CDS family
CLM75_RS27955	COG1522	sequence-specific DNA binding
CLM75_RS27960	COG1280	lysine exporter protein (LysE YggA)
CLM75_RS27965	COG2373	Large extracellular alpha-helical protein
CLM75_RS27970	COG4953	penicillin-binding protein 1C
CLM75_RS27980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CLM75_RS27985	COG1349	DNA-binding transcription factor activity
CLM75_RS27990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLM75_RS28000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLM75_RS28005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLM75_RS28010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLM75_RS28015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLM75_RS28020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLM75_RS28025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLM75_RS28035	COG0356	it plays a direct role in the translocation of protons across the membrane
CLM75_RS28040	COG3312	ion transport
CLM75_RS28045	COG1475	DNA binding
CLM75_RS28050	COG1192	Involved in chromosome partitioning
CLM75_RS28055	COG0357	Ribosomal RNA small subunit methyltransferase G
CLM75_RS28060	COG0445	tRNA wobble uridine modification
CLM75_RS28065	COG1595	DNA-templated transcription, initiation
CLM75_RS28070	COG3712	iron ion homeostasis
CLM75_RS28075	COG4774	siderophore transport
CLM75_RS28080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLM75_RS28085	COG0706	membrane insertase activity
CLM75_RS28090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CLM75_RS28095	COG0594	ribonuclease P activity
CLM75_RS28100	COG0230	Belongs to the bacterial ribosomal protein bL34 family