locus-tag	class	description
G4G71_RS00050	COG0840	transmembrane signaling receptor activity
G4G71_RS00060	COG0174	glutamine synthetase
G4G71_RS00070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS00080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G71_RS00090	COG2258	MOSC domain
G4G71_RS00095	COG0583	DNA-binding transcription factor activity
G4G71_RS00100	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS00105	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS00115	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS00135	COG2226	methyltransferase
G4G71_RS00135	COG1073	alpha beta
G4G71_RS00155	COG1040	competence protein
G4G71_RS00160	COG3585	molybdate ion transport
G4G71_RS00160	COG2005	Transcriptional regulator
G4G71_RS00170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G71_RS00200	COG1953	Uracil, thiamine, allantoin
G4G71_RS00205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G4G71_RS00215	COG0625	glutathione transferase activity
G4G71_RS00220	COG1595	DNA-templated transcription, initiation
G4G71_RS00225	COG3712	iron ion homeostasis
G4G71_RS00230	COG4774	siderophore transport
G4G71_RS00260	COG4452	Inner membrane protein CreD
G4G71_RS00265	COG2205	protein histidine kinase activity
G4G71_RS00270	COG0745	RESPONSE REGULATOR receiver
G4G71_RS00280	COG0204	Acyl-transferase
G4G71_RS00295	COG0477	Major facilitator Superfamily
G4G71_RS00310	COG0513	Belongs to the DEAD box helicase family
G4G71_RS00315	COG1289	transmembrane transporter activity
G4G71_RS00320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS00330	COG0281	malic enzyme
G4G71_RS00350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4G71_RS00440	COG0140	phosphoribosyl-ATP diphosphatase activity
G4G71_RS00465	COG0840	transmembrane signaling receptor activity
G4G71_RS00470	COG0840	transmembrane signaling receptor activity
G4G71_RS00505	COG3038	cytochrome b561
G4G71_RS00520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G4G71_RS00530	COG2207	Transcriptional regulator
G4G71_RS00530	COG1917	Cupin 2, conserved barrel domain protein
G4G71_RS00545	COG0643	Histidine kinase
G4G71_RS00545	COG2198	Histidine kinase
G4G71_RS00545	COG0784	Response regulator, receiver
G4G71_RS00550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G4G71_RS00550	COG0457	Tetratricopeptide repeat
G4G71_RS00610	COG0626	cystathionine gamma-synthase activity
G4G71_RS00615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4G71_RS00650	COG1872	DUF167
G4G71_RS00665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G4G71_RS00665	COG2813	Specifically methylates the guanine in position
G4G71_RS00680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4G71_RS00705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G4G71_RS00720	COG2363	Small membrane protein
G4G71_RS00740	COG2177	Part of the ABC transporter FtsEX involved in
G4G71_RS00745	COG2884	Cell division ATP-binding protein ftsE
G4G71_RS00750	COG0552	protein localization to endoplasmic reticulum
G4G71_RS00755	COG0612	Peptidase, M16
G4G71_RS00760	COG0612	Peptidase, M16
G4G71_RS00765	COG0742	ribosomal rna small subunit methyltransferase
G4G71_RS00785	COG0429	hydrolase of the alpha beta-hydrolase fold
G4G71_RS00810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G4G71_RS00815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G4G71_RS00820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G4G71_RS00855	COG0494	nUDIX hydrolase
G4G71_RS00860	COG1011	Hydrolase
G4G71_RS00865	COG1652	LysM domain
G4G71_RS00875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G4G71_RS00905	COG0824	Thioesterase
G4G71_RS00910	COG1454	alcohol dehydrogenase
G4G71_RS00970	COG1178	ABC-type Fe3 transport system permease component
G4G71_RS00985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4G71_RS00995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4G71_RS01000	COG0006	proline dipeptidase activity
G4G71_RS01025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G4G71_RS01035	COG3300	MHYT domain
G4G71_RS01035	COG5001	Diguanylate cyclase
G4G71_RS01040	COG0842	Transport permease protein
G4G71_RS01045	COG0842	Transport permease protein
G4G71_RS01045	COG1129	ABC transporter
G4G71_RS01050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS01060	COG0604	alcohol dehydrogenase
G4G71_RS01065	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS01075	COG0154	amidase activity
G4G71_RS01085	COG1177	transmembrane transport
G4G71_RS01090	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS01095	COG3842	ATPase activity
G4G71_RS01100	COG0583	DNA-binding transcription factor activity
G4G71_RS01125	COG0248	Ppx GppA phosphatase
G4G71_RS01140	COG0586	Pfam SNARE associated Golgi protein
G4G71_RS01150	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G4G71_RS01155	COG1671	Belongs to the UPF0178 family
G4G71_RS01160	COG0672	)-iron permease
G4G71_RS01165	COG1280	lysine exporter protein (LysE YggA)
G4G71_RS01170	COG0861	Integral membrane protein TerC family
G4G71_RS01180	COG0488	(ABC) transporter
G4G71_RS01240	COG2972	Histidine kinase
G4G71_RS01240	COG0745	RESPONSE REGULATOR receiver
G4G71_RS01250	COG0745	RESPONSE REGULATOR receiver
G4G71_RS01290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G4G71_RS01295	COG0501	Belongs to the peptidase M48B family
G4G71_RS01310	COG4771	TonB-dependent receptor
G4G71_RS01315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS01355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS01375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS01380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS01390	COG0659	secondary active sulfate transmembrane transporter activity
G4G71_RS01395	COG2076	Multidrug Resistance protein
G4G71_RS01410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4G71_RS01415	COG1256	bacterial-type flagellum assembly
G4G71_RS01415	COG4786	Flagellar basal body rod
G4G71_RS01420	COG0741	lytic transglycosylase activity
G4G71_RS01425	COG1706	bacterial-type flagellum-dependent cell motility
G4G71_RS01430	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G4G71_RS01435	COG4786	Flagellar basal body rod
G4G71_RS01440	COG4787	bacterial-type flagellum-dependent cell motility
G4G71_RS01445	COG1749	Flagellar hook protein flgE
G4G71_RS01455	COG1558	bacterial-type flagellum-dependent cell motility
G4G71_RS01460	COG1815	bacterial-type flagellum-dependent cell motility
G4G71_RS01470	COG4589	Belongs to the CDS family
G4G71_RS01485	COG0671	phosphoesterase, PA-phosphatase related
G4G71_RS01485	COG2453	phosphatase
G4G71_RS01490	COG2267	carboxylic ester hydrolase activity
G4G71_RS01495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G4G71_RS01500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4G71_RS01520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4G71_RS01525	COG1191	sigma factor activity
G4G71_RS01550	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G4G71_RS01585	COG1766	The M ring may be actively involved in energy transduction
G4G71_RS01590	COG1677	Flagellar hook-basal body complex protein FliE
G4G71_RS01615	COG1987	bacterial-type flagellum assembly
G4G71_RS01620	COG1684	flagellar biosynthetic protein fliR
G4G71_RS01655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4G71_RS01675	COG0583	DNA-binding transcription factor activity
G4G71_RS01685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G4G71_RS01695	COG0387	Pfam Sodium calcium exchanger
G4G71_RS01710	COG0523	cobalamin synthesis protein
G4G71_RS01745	COG0456	acetyltransferase
G4G71_RS01750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G4G71_RS01755	COG0477	Major facilitator Superfamily
G4G71_RS01760	COG0477	Major facilitator Superfamily
G4G71_RS01770	COG1349	DNA-binding transcription factor activity
G4G71_RS01830	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G4G71_RS01835	COG0735	belongs to the Fur family
G4G71_RS01845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4G71_RS01860	COG2011	ABC-type metal ion transport system permease component
G4G71_RS01895	COG0154	amidase activity
G4G71_RS01920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G4G71_RS01930	COG0840	transmembrane signaling receptor activity
G4G71_RS01940	COG1309	transcriptional regulator
G4G71_RS01955	COG2207	Transcriptional regulator
G4G71_RS01960	COG0477	Major facilitator Superfamily
G4G71_RS01965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4G71_RS01970	COG0390	transport system, permease component
G4G71_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS01990	COG0745	RESPONSE REGULATOR receiver
G4G71_RS01995	COG2198	Histidine kinase
G4G71_RS01995	COG0643	Histidine kinase
G4G71_RS02000	COG0835	chemotaxis
G4G71_RS02005	COG0840	transmembrane signaling receptor activity
G4G71_RS02015	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G4G71_RS02040	COG3706	GGDEF domain
G4G71_RS02055	COG0454	-acetyltransferase
G4G71_RS02065	COG4115	mRNA cleavage
G4G71_RS02070	COG2161	toxin-antitoxin pair type II binding
G4G71_RS02095	COG2072	flavoprotein involved in K transport
G4G71_RS02135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G4G71_RS02140	COG0339	signal peptide processing
G4G71_RS02145	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G4G71_RS02150	COG0306	phosphate transporter
G4G71_RS02170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4G71_RS02175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4G71_RS02180	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G4G71_RS02235	COG0427	acetyl-CoA hydrolase
G4G71_RS02250	COG0438	transferase activity, transferring glycosyl groups
G4G71_RS02270	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G4G71_RS02270	COG0662	Cupin 2, conserved barrel domain protein
G4G71_RS02285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4G71_RS02285	COG2755	lipolytic protein G-D-S-L family
G4G71_RS02290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4G71_RS02290	COG2755	lipolytic protein G-D-S-L family
G4G71_RS02295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4G71_RS02315	COG0463	Glycosyl transferase, family 2
G4G71_RS02380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G71_RS02405	COG2153	protein acetylation
G4G71_RS02410	COG2207	Transcriptional regulator
G4G71_RS02415	COG2267	carboxylic ester hydrolase activity
G4G71_RS02450	COG1024	Enoyl-CoA hydratase
G4G71_RS02450	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS02455	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS02475	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS02480	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS02515	COG1764	response to oxidative stress
G4G71_RS02525	COG3360	Dodecin
G4G71_RS02565	COG0346	lactoylglutathione lyase activity
G4G71_RS02570	COG2207	Transcriptional regulator
G4G71_RS02590	COG1595	DNA-templated transcription, initiation
G4G71_RS02600	COG0583	DNA-binding transcription factor activity
G4G71_RS02605	COG3119	arylsulfatase activity
G4G71_RS02615	COG0659	secondary active sulfate transmembrane transporter activity
G4G71_RS02620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4G71_RS02640	COG0758	DNA mediated transformation
G4G71_RS02645	COG1652	LysM domain
G4G71_RS02665	COG0569	domain protein
G4G71_RS02670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4G71_RS02680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4G71_RS02685	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS02690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G4G71_RS02695	COG1522	sequence-specific DNA binding
G4G71_RS02700	COG3608	succinylglutamate desuccinylase aspartoacylase
G4G71_RS02705	COG0006	proline dipeptidase activity
G4G71_RS02710	COG2423	ornithine cyclodeaminase activity
G4G71_RS02715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G4G71_RS02720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS02725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS02730	COG0765	amino acid transport
G4G71_RS02735	COG0765	amino acid transport
G4G71_RS02740	COG1126	abc transporter atp-binding protein
G4G71_RS02750	COG1914	H( )-stimulated, divalent metal cation uptake system
G4G71_RS02775	COG2818	Glycosylase
G4G71_RS02830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G4G71_RS02855	COG1192	Involved in chromosome partitioning
G4G71_RS02860	COG1475	DNA binding
G4G71_RS02865	COG3312	ion transport
G4G71_RS02910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G4G71_RS02915	COG2095	MarC family integral membrane protein
G4G71_RS02925	COG5002	protein histidine kinase activity
G4G71_RS02965	COG1301	dicarboxylic acid transport
G4G71_RS02970	COG0700	Nucleoside recognition
G4G71_RS03020	COG0861	Integral membrane protein TerC family
G4G71_RS03025	COG2851	Citrate transporter
G4G71_RS03040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS03075	COG3246	L-lysine catabolic process to acetate
G4G71_RS03085	COG0824	Thioesterase
G4G71_RS03085	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS03110	COG1760	l-serine dehydratase
G4G71_RS03125	COG4176	ABC-type proline glycine betaine transport system permease component
G4G71_RS03135	COG0596	Alpha beta hydrolase
G4G71_RS03150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G4G71_RS03175	COG0833	amino acid
G4G71_RS03180	COG1024	Enoyl-CoA hydratase
G4G71_RS03185	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS03210	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4G71_RS03235	COG4191	Histidine kinase
G4G71_RS03265	COG4651	solute:proton antiporter activity
G4G71_RS03265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G4G71_RS03270	COG1607	acyl-coa hydrolase
G4G71_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS03280	COG0174	glutamine synthetase
G4G71_RS03285	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G4G71_RS03315	COG0475	glutathione-regulated potassium exporter activity
G4G71_RS03335	COG0714	Associated with various cellular activities
G4G71_RS03340	COG1845	cytochrome c oxidase, subunit III
G4G71_RS03350	COG2010	Cytochrome c
G4G71_RS03355	COG3256	nitric oxide reductase
G4G71_RS03370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G71_RS03375	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
G4G71_RS03380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G71_RS03410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G4G71_RS03425	COG0583	DNA-binding transcription factor activity
G4G71_RS03430	COG0439	Biotin carboxylase
G4G71_RS03435	COG5016	pyruvate
G4G71_RS03435	COG0511	ligase activity, forming carbon-carbon bonds
G4G71_RS03455	COG2824	Alkylphosphonate utilization operon protein PhnA
G4G71_RS03470	COG0583	DNA-binding transcription factor activity
G4G71_RS03475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G71_RS03480	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS03495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G71_RS03565	COG0393	Putative heavy-metal-binding
G4G71_RS03575	COG1017	nitric oxide dioxygenase activity
G4G71_RS03575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4G71_RS03595	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4G71_RS03595	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS03600	COG0247	lactate metabolic process
G4G71_RS03600	COG2181	nitrate reductase activity
G4G71_RS03605	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G4G71_RS03630	COG0583	DNA-binding transcription factor activity
G4G71_RS03645	COG4774	siderophore transport
G4G71_RS03675	COG0676	glucose-6-phosphate 1-epimerase activity
G4G71_RS03700	COG1131	(ABC) transporter
G4G71_RS03705	COG0842	Transport permease protein
G4G71_RS03735	COG1607	acyl-coa hydrolase
G4G71_RS03740	COG0477	Major facilitator Superfamily
G4G71_RS03785	COG0581	inorganic phosphate transmembrane transporter activity
G4G71_RS03805	COG0739	heme binding
G4G71_RS03810	COG1253	flavin adenine dinucleotide binding
G4G71_RS03870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G4G71_RS03885	COG1917	Cupin 2, conserved barrel domain protein
G4G71_RS03885	COG2207	Transcriptional regulator
G4G71_RS03905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4G71_RS03920	COG1561	YicC-like family, N-terminal region
G4G71_RS03935	COG0708	Exodeoxyribonuclease III
G4G71_RS03950	COG0824	Thioesterase
G4G71_RS03965	COG0756	dUTP diphosphatase activity
G4G71_RS03970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4G71_RS03980	COG0747	negative chemotaxis
G4G71_RS04000	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS04005	COG2814	Major facilitator Superfamily
G4G71_RS04010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G71_RS04015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS04055	COG1396	sequence-specific DNA binding
G4G71_RS04055	COG1917	Cupin 2, conserved barrel domain protein
G4G71_RS04065	COG0427	acetyl-CoA hydrolase
G4G71_RS04090	COG0583	DNA-binding transcription factor activity
G4G71_RS04095	COG1917	Cupin 2, conserved barrel domain protein
G4G71_RS04095	COG4977	sequence-specific DNA binding
G4G71_RS04115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G71_RS04120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS04135	COG0606	chelatase, subunit chli
G4G71_RS04145	COG0347	Belongs to the P(II) protein family
G4G71_RS04150	COG0004	ammonium transporteR
G4G71_RS04155	COG0432	Pfam Uncharacterised protein family UPF0047
G4G71_RS04165	COG1011	Hydrolase
G4G71_RS04215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4G71_RS04255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G71_RS04280	COG4221	oxidoreductase activity
G4G71_RS04285	COG1309	transcriptional regulator
G4G71_RS04300	COG4208	sulfate ABC transporter
G4G71_RS04310	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G4G71_RS04330	COG3706	GGDEF domain
G4G71_RS04375	COG0438	transferase activity, transferring glycosyl groups
G4G71_RS04390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G4G71_RS04395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4G71_RS04410	COG2957	Belongs to the agmatine deiminase family
G4G71_RS04425	COG0174	glutamine synthetase
G4G71_RS04430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G4G71_RS04435	COG0174	glutamine synthetase
G4G71_RS04455	COG3842	ATPase activity
G4G71_RS04460	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS04465	COG1177	transmembrane transport
G4G71_RS04510	COG1683	Conserved Protein
G4G71_RS04520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4G71_RS04525	COG0277	FAD linked oxidase domain protein
G4G71_RS04530	COG0179	Fumarylacetoacetate (FAA) hydrolase
G4G71_RS04540	COG3111	PFAM Bacterial OB fold (BOF) protein
G4G71_RS04550	COG0531	amino acid
G4G71_RS04555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G4G71_RS04560	COG1177	transmembrane transport
G4G71_RS04570	COG3842	ATPase activity
G4G71_RS04585	COG2234	aminopeptidase activity
G4G71_RS04600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G4G71_RS04620	COG0494	nUDIX hydrolase
G4G71_RS04625	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
G4G71_RS04635	COG0730	response to heat
G4G71_RS04650	COG0330	HflC and HflK could
G4G71_RS04655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G4G71_RS04690	COG2183	response to ionizing radiation
G4G71_RS04695	COG0745	RESPONSE REGULATOR receiver
G4G71_RS04715	COG4067	protein conserved in archaea
G4G71_RS04715	COG0189	ligase activity
G4G71_RS04720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G4G71_RS04750	COG0778	Nitroreductase
G4G71_RS04765	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS04790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G4G71_RS04800	COG2233	PERMEase
G4G71_RS04810	COG0129	dihydroxy-acid dehydratase activity
G4G71_RS04825	COG0693	protein deglycase activity
G4G71_RS04880	COG1091	dTDP-4-dehydrorhamnose reductase activity
G4G71_RS04885	COG1088	dTDP-glucose 4,6-dehydratase activity
G4G71_RS04895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G4G71_RS04920	COG0110	maltose O-acetyltransferase activity
G4G71_RS04940	COG2814	Major facilitator Superfamily
G4G71_RS04945	COG1566	PFAM secretion protein HlyD family protein
G4G71_RS04975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS04985	COG3408	Glycogen debranching enzyme
G4G71_RS04985	COG3119	arylsulfatase activity
G4G71_RS04995	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G4G71_RS05000	COG1194	a g-specific adenine glycosylase
G4G71_RS05050	COG2861	carbohydrate metabolic process
G4G71_RS05055	COG0793	Belongs to the peptidase S41A family
G4G71_RS05060	COG4942	peptidase
G4G71_RS05070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4G71_RS05090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G4G71_RS05100	COG3852	Histidine kinase
G4G71_RS05115	COG0668	transmembrane transport
G4G71_RS05170	COG0402	S-adenosylhomocysteine deaminase activity
G4G71_RS05185	COG2986	histidine ammonia-lyase
G4G71_RS05195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G4G71_RS05200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G71_RS05210	COG4176	ABC-type proline glycine betaine transport system permease component
G4G71_RS05215	COG0517	IMP dehydrogenase activity
G4G71_RS05215	COG4175	Glycine betaine
G4G71_RS05220	COG2986	histidine ammonia-lyase
G4G71_RS05250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS05255	COG0494	nUDIX hydrolase
G4G71_RS05270	COG1490	D-aminoacyl-tRNA deacylase activity
G4G71_RS05290	COG0765	amino acid transport
G4G71_RS05295	COG1126	abc transporter atp-binding protein
G4G71_RS05300	COG0513	Belongs to the DEAD box helicase family
G4G71_RS05305	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G4G71_RS05310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4G71_RS05315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G4G71_RS05320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G4G71_RS05325	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS05330	COG0583	DNA-binding transcription factor activity
G4G71_RS05340	COG4521	taurine ABC transporter
G4G71_RS05355	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G4G71_RS05395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4G71_RS05400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G4G71_RS05415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G4G71_RS05420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4G71_RS05425	COG0126	phosphoglycerate kinase activity
G4G71_RS05450	COG1451	nucleotide metabolic process
G4G71_RS05505	COG0067	glutamate synthase
G4G71_RS05505	COG0069	glutamate synthase activity
G4G71_RS05505	COG0070	glutamate synthase
G4G71_RS05510	COG0493	'glutamate synthase
G4G71_RS05525	COG2814	Major facilitator Superfamily
G4G71_RS05530	COG0583	DNA-binding transcription factor activity
G4G71_RS05535	COG1192	Involved in chromosome partitioning
G4G71_RS05555	COG0840	transmembrane signaling receptor activity
G4G71_RS05560	COG2873	o-acetylhomoserine
G4G71_RS05565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G4G71_RS05570	COG1196	nuclear chromosome segregation
G4G71_RS05570	COG3264	Mechanosensitive ion channel
G4G71_RS05585	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS05590	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G4G71_RS05595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G4G71_RS05620	COG0859	PFAM glycosyl transferase family 9
G4G71_RS05630	COG0438	transferase activity, transferring glycosyl groups
G4G71_RS05655	COG2192	nodulation
G4G71_RS05660	COG0438	transferase activity, transferring glycosyl groups
G4G71_RS05695	COG1132	(ABC) transporter
G4G71_RS05720	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS05730	COG0667	Aldo Keto reductase
G4G71_RS05750	COG1519	Transferase
G4G71_RS05765	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4G71_RS05765	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS05785	COG1538	Outer membrane efflux protein
G4G71_RS05795	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G71_RS05805	COG0494	nUDIX hydrolase
G4G71_RS05815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G4G71_RS05820	COG3150	esterase
G4G71_RS05835	COG3577	Aspartyl protease
G4G71_RS05860	COG1988	membrane-bound metal-dependent
G4G71_RS05870	COG0560	Phosphoserine phosphatase
G4G71_RS05870	COG3830	Belongs to the UPF0237 family
G4G71_RS05875	COG5002	protein histidine kinase activity
G4G71_RS05875	COG5001	Diguanylate cyclase
G4G71_RS05930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G4G71_RS05930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G4G71_RS05935	COG0802	atpase or kinase
G4G71_RS05940	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4G71_RS05950	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G4G71_RS05960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G4G71_RS05965	COG0330	HflC and HflK could
G4G71_RS05970	COG0330	HflC and HflK could
G4G71_RS06005	COG0557	exoribonuclease II activity
G4G71_RS06015	COG0360	Binds together with S18 to 16S ribosomal RNA
G4G71_RS06035	COG0305	Participates in initiation and elongation during chromosome replication
G4G71_RS06045	COG3300	MHYT domain
G4G71_RS06045	COG5001	Diguanylate cyclase
G4G71_RS06055	COG2703	oxygen carrier activity
G4G71_RS06070	COG0668	transmembrane transport
G4G71_RS06110	COG1272	protein, Hemolysin III
G4G71_RS06115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G4G71_RS06135	COG0583	DNA-binding transcription factor activity
G4G71_RS06140	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS06145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS06180	COG4221	oxidoreductase activity
G4G71_RS06200	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G4G71_RS06250	COG2982	Protein involved in outer membrane biogenesis
G4G71_RS06270	COG0443	Heat shock 70 kDa protein
G4G71_RS06285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4G71_RS06310	COG0832	Belongs to the urease beta subunit family
G4G71_RS06320	COG0831	urea catabolic process
G4G71_RS06355	COG0683	leucine binding
G4G71_RS06360	COG2095	MarC family integral membrane protein
G4G71_RS06420	COG0583	DNA-binding transcription factor activity
G4G71_RS06430	COG0010	Belongs to the arginase family
G4G71_RS06455	COG0023	Translation Initiation Factor
G4G71_RS06475	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G4G71_RS06475	COG1328	CTP reductase activity
G4G71_RS06485	COG0484	heat shock protein binding
G4G71_RS06490	COG0789	Transcriptional regulator
G4G71_RS06500	COG0431	NADPH-dependent FMN reductase
G4G71_RS06535	COG0534	Mate efflux family protein
G4G71_RS06545	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G4G71_RS06550	COG0494	nUDIX hydrolase
G4G71_RS06565	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4G71_RS06565	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS06580	COG0437	4 iron, 4 sulfur cluster binding
G4G71_RS06585	COG2864	formate dehydrogenase
G4G71_RS06600	COG3276	selenocysteine insertion sequence binding
G4G71_RS06670	COG4974	Belongs to the 'phage' integrase family
G4G71_RS06705	COG0509	glycine decarboxylation via glycine cleavage system
G4G71_RS06735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4G71_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS06765	COG0183	Belongs to the thiolase family
G4G71_RS06770	COG1522	sequence-specific DNA binding
G4G71_RS06775	COG0697	spore germination
G4G71_RS06790	COG0583	DNA-binding transcription factor activity
G4G71_RS06795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS06800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS06810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS06815	COG4521	taurine ABC transporter
G4G71_RS06825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS06830	COG2175	clavaminate synthase activity
G4G71_RS06835	COG1297	OPT oligopeptide transporter protein
G4G71_RS06840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G4G71_RS06855	COG0626	cystathionine gamma-synthase activity
G4G71_RS06865	COG1271	oxidase subunit
G4G71_RS06870	COG1294	oxidase, subunit
G4G71_RS06880	COG2814	Major facilitator Superfamily
G4G71_RS06895	COG2010	Cytochrome c
G4G71_RS06900	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G4G71_RS06900	COG3608	succinylglutamate desuccinylase aspartoacylase
G4G71_RS06905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G4G71_RS06940	COG1253	flavin adenine dinucleotide binding
G4G71_RS06945	COG1970	mechanosensitive ion channel activity
G4G71_RS06975	COG1966	Carbon starvation protein
G4G71_RS06980	COG2879	small protein
G4G71_RS06985	COG0523	cobalamin synthesis protein
G4G71_RS06995	COG3842	ATPase activity
G4G71_RS07000	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS07005	COG1177	transmembrane transport
G4G71_RS07015	COG0402	S-adenosylhomocysteine deaminase activity
G4G71_RS07020	COG0402	S-adenosylhomocysteine deaminase activity
G4G71_RS07025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4G71_RS07035	COG1134	teichoic acid transport
G4G71_RS07050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4G71_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS07170	COG4974	Belongs to the 'phage' integrase family
G4G71_RS07205	COG0642	Histidine kinase
G4G71_RS07220	COG1304	FMN binding
G4G71_RS07250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4G71_RS07260	COG0497	DNA recombination
G4G71_RS07315	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G4G71_RS07320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4G71_RS07325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G4G71_RS07360	COG0195	Participates in both transcription termination and antitermination
G4G71_RS07370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G4G71_RS07380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G4G71_RS07425	COG2197	response regulator
G4G71_RS07480	COG4191	Histidine kinase
G4G71_RS07495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4G71_RS07515	COG3720	iron ion transport
G4G71_RS07520	COG4558	Periplasmic binding protein
G4G71_RS07525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4G71_RS07555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4G71_RS07565	COG3098	single-species biofilm formation
G4G71_RS07575	COG0028	Belongs to the TPP enzyme family
G4G71_RS07590	COG1183	phosphatidylcholine synthase activity
G4G71_RS07595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4G71_RS07600	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G4G71_RS07655	COG2995	paraquat-inducible protein a
G4G71_RS07660	COG2995	paraquat-inducible protein a
G4G71_RS07665	COG3008	intermembrane lipid transfer
G4G71_RS07710	COG0456	acetyltransferase
G4G71_RS07725	COG0288	reversible hydration of carbon dioxide
G4G71_RS07730	COG0473	3-isopropylmalate dehydrogenase activity
G4G71_RS07805	COG4128	Pfam Zonular occludens toxin
G4G71_RS07815	COG4974	Belongs to the 'phage' integrase family
G4G71_RS07835	COG2161	toxin-antitoxin pair type II binding
G4G71_RS07880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G4G71_RS07910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4G71_RS07925	COG0415	Belongs to the DNA photolyase family
G4G71_RS07930	COG0789	Transcriptional regulator
G4G71_RS07935	COG3272	Protein of unknown function (DUF1722)
G4G71_RS07940	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
G4G71_RS07945	COG1090	epimerase
G4G71_RS07965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G71_RS07970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS08030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G71_RS08045	COG1918	ferrous iron import across plasma membrane
G4G71_RS08060	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS08065	COG2814	Major facilitator Superfamily
G4G71_RS08075	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G4G71_RS08080	COG0589	response to stress
G4G71_RS08100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4G71_RS08100	COG0426	domain, Protein
G4G71_RS08120	COG0477	Major facilitator Superfamily
G4G71_RS08125	COG0583	DNA-binding transcription factor activity
G4G71_RS08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G71_RS08170	COG0667	Aldo Keto reductase
G4G71_RS08180	COG0477	Major facilitator Superfamily
G4G71_RS08190	COG0693	protein deglycase activity
G4G71_RS08205	COG3706	GGDEF domain
G4G71_RS08215	COG1024	Enoyl-CoA hydratase
G4G71_RS08225	COG0589	response to stress
G4G71_RS08255	COG0714	Associated with various cellular activities
G4G71_RS08285	COG2925	Exonuclease
G4G71_RS08295	COG0788	formyltetrahydrofolate deformylase activity
G4G71_RS08315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G4G71_RS08330	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS08390	COG2135	peptidase activity
G4G71_RS08395	COG0840	transmembrane signaling receptor activity
G4G71_RS08400	COG0501	Belongs to the peptidase M48B family
G4G71_RS08415	COG2119	membrane
G4G71_RS08420	COG0833	amino acid
G4G71_RS08435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4G71_RS08445	COG1280	lysine exporter protein (LysE YggA)
G4G71_RS08450	COG0183	Belongs to the thiolase family
G4G71_RS08455	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G71_RS08505	COG0204	Acyl-transferase
G4G71_RS08530	COG0386	Belongs to the glutathione peroxidase family
G4G71_RS08545	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G71_RS08550	COG0583	DNA-binding transcription factor activity
G4G71_RS08555	COG1309	transcriptional regulator
G4G71_RS08565	COG1307	EDD domain protein, DegV family
G4G71_RS08580	COG5001	Diguanylate cyclase
G4G71_RS08585	COG0492	ferredoxin-NADP+ reductase activity
G4G71_RS08590	COG0183	Belongs to the thiolase family
G4G71_RS08605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4G71_RS08610	COG1126	abc transporter atp-binding protein
G4G71_RS08620	COG0583	DNA-binding transcription factor activity
G4G71_RS08630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS08645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G4G71_RS08670	COG0583	DNA-binding transcription factor activity
G4G71_RS08675	COG1380	Effector of murein hydrolase LrgA
G4G71_RS08680	COG1346	cytolysis
G4G71_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS08710	COG1024	Enoyl-CoA hydratase
G4G71_RS08740	COG2197	response regulator
G4G71_RS08770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS08800	COG1595	DNA-templated transcription, initiation
G4G71_RS08810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4G71_RS08815	COG0697	spore germination
G4G71_RS08820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS08825	COG4774	siderophore transport
G4G71_RS08855	COG0697	spore germination
G4G71_RS08860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4G71_RS08865	COG0583	DNA-binding transcription factor activity
G4G71_RS08885	COG1566	PFAM secretion protein HlyD family protein
G4G71_RS08910	COG0300	oxidoreductase activity
G4G71_RS08980	COG3022	response to hydroperoxide
G4G71_RS08985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G4G71_RS08990	COG0315	cyclic pyranopterin monophosphate synthase activity
G4G71_RS08995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G4G71_RS09005	COG0521	Mo-molybdopterin cofactor biosynthetic process
G4G71_RS09010	COG0303	'Molybdopterin
G4G71_RS09015	COG0826	peptidase U32
G4G71_RS09020	COG0826	peptidase U32
G4G71_RS09025	COG3154	lipid carrier protein
G4G71_RS09035	COG2197	response regulator
G4G71_RS09040	COG3850	Histidine kinase
G4G71_RS09050	COG2223	nitrite transmembrane transporter activity
G4G71_RS09055	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G4G71_RS09060	COG1140	nitrate reductase beta subunit
G4G71_RS09065	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G4G71_RS09070	COG2181	nitrate reductase activity
G4G71_RS09085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS09105	COG0840	transmembrane signaling receptor activity
G4G71_RS09120	COG3706	GGDEF domain
G4G71_RS09125	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS09130	COG0400	carboxylic ester hydrolase activity
G4G71_RS09135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS09140	COG4597	amino acid ABC transporter
G4G71_RS09145	COG0765	amino acid transport
G4G71_RS09150	COG1126	abc transporter atp-binding protein
G4G71_RS09205	COG0420	3'-5' exonuclease activity
G4G71_RS09210	COG0419	ATPase involved in DNA repair
G4G71_RS09220	COG0783	Belongs to the Dps family
G4G71_RS09240	COG0583	DNA-binding transcription factor activity
G4G71_RS09245	COG0477	Major facilitator Superfamily
G4G71_RS09250	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G4G71_RS09265	COG0490	domain, Protein
G4G71_RS09265	COG0471	metal ion transport
G4G71_RS09270	COG0028	Belongs to the TPP enzyme family
G4G71_RS09300	COG0795	lipopolysaccharide-transporting ATPase activity
G4G71_RS09305	COG0795	lipopolysaccharide-transporting ATPase activity
G4G71_RS09315	COG2200	EAL domain
G4G71_RS09335	COG1862	Preprotein translocase
G4G71_RS09350	COG3134	Outer membrane lipoprotein
G4G71_RS09365	COG1045	serine acetyltransferase
G4G71_RS09385	COG0316	Belongs to the HesB IscA family
G4G71_RS09425	COG1426	Protein conserved in bacteria
G4G71_RS09455	COG0436	Aminotransferase
G4G71_RS09460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G71_RS09480	COG2814	Major facilitator Superfamily
G4G71_RS09490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4G71_RS09525	COG0739	heme binding
G4G71_RS09535	COG1570	exodeoxyribonuclease VII activity
G4G71_RS09550	COG2132	Multicopper oxidase
G4G71_RS09555	COG0590	tRNA wobble adenosine to inosine editing
G4G71_RS09575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4G71_RS09620	COG0477	Major facilitator Superfamily
G4G71_RS09625	COG4536	flavin adenine dinucleotide binding
G4G71_RS09635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G4G71_RS09640	COG0228	four-way junction DNA binding
G4G71_RS09645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G4G71_RS09655	COG0335	large ribosomal subunit rRNA binding
G4G71_RS09660	COG1607	acyl-coa hydrolase
G4G71_RS09680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G4G71_RS09745	COG3639	organic phosphonate transmembrane transporter activity
G4G71_RS09755	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G4G71_RS09760	COG2084	Dehydrogenase
G4G71_RS09765	COG3622	Belongs to the hyi family
G4G71_RS09780	COG0589	response to stress
G4G71_RS09820	COG2814	Major facilitator Superfamily
G4G71_RS09825	COG2030	dehydratase
G4G71_RS09830	COG2267	carboxylic ester hydrolase activity
G4G71_RS09835	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS09840	COG2841	Protein conserved in bacteria
G4G71_RS09845	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS09855	COG1643	Atp-dependent helicase
G4G71_RS09860	COG0625	glutathione transferase activity
G4G71_RS09865	COG0537	adenosine 5'-monophosphoramidase activity
G4G71_RS09875	COG3706	GGDEF domain
G4G71_RS09880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4G71_RS09885	COG2814	Major facilitator Superfamily
G4G71_RS09905	COG1595	DNA-templated transcription, initiation
G4G71_RS09930	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS09935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G4G71_RS09970	COG0791	NLP P60 protein
G4G71_RS09975	COG0791	NLP P60 protein
G4G71_RS10035	COG1127	ABC transporter
G4G71_RS10040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G4G71_RS10055	COG0778	Nitroreductase
G4G71_RS10075	COG1492	cobalamin metabolic process
G4G71_RS10100	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS10130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G4G71_RS10145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G4G71_RS10190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4G71_RS10230	COG2831	hemolysin activation secretion protein
G4G71_RS10260	COG0783	Belongs to the Dps family
G4G71_RS10295	COG0824	Thioesterase
G4G71_RS10320	COG2885	chlorophyll binding
G4G71_RS10325	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G4G71_RS10330	COG0602	queuosine metabolic process
G4G71_RS10350	COG4783	chaperone-mediated protein folding
G4G71_RS10355	COG0425	Belongs to the sulfur carrier protein TusA family
G4G71_RS10365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G4G71_RS10380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G4G71_RS10385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G4G71_RS10480	COG4128	Pfam Zonular occludens toxin
G4G71_RS10510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G71_RS10600	COG4772	TonB-dependent receptor
G4G71_RS10615	COG2076	Multidrug Resistance protein
G4G71_RS10620	COG0385	Bile acid
G4G71_RS10640	COG0545	Peptidyl-prolyl cis-trans isomerase
G4G71_RS10645	COG3339	Conserved Protein
G4G71_RS10670	COG2200	EAL domain
G4G71_RS10670	COG2199	diguanylate cyclase activity
G4G71_RS10700	COG0395	ABC-type sugar transport system, permease component
G4G71_RS10725	COG1362	aminopeptidase activity
G4G71_RS10740	COG2894	cell division
G4G71_RS10750	COG1560	Kdo2-lipid A biosynthetic process
G4G71_RS10765	COG2853	Lipoprotein
G4G71_RS10805	COG3162	membrane
G4G71_RS10810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G71_RS10855	COG1363	Peptidase, m42
G4G71_RS10860	COG0189	ligase activity
G4G71_RS10860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G4G71_RS10865	COG0367	asparagine synthase
G4G71_RS10870	COG0582	viral genome integration into host DNA
G4G71_RS10935	COG3723	Recombinational DNA repair protein, rece pathway
G4G71_RS11230	COG3179	chitinase
G4G71_RS11270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4G71_RS11280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4G71_RS11290	COG4172	Belongs to the ABC transporter superfamily
G4G71_RS11295	COG4239	(ABC) transporter, permease
G4G71_RS11300	COG4174	ABC transporter (Permease)
G4G71_RS11305	COG4166	transmembrane transport
G4G71_RS11310	COG4166	transmembrane transport
G4G71_RS11315	COG1388	LysM domain
G4G71_RS11315	COG0741	lytic transglycosylase activity
G4G71_RS11335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4G71_RS11340	COG1982	Orn Lys Arg decarboxylase major
G4G71_RS11350	COG0531	amino acid
G4G71_RS11355	COG1024	Enoyl-CoA hydratase
G4G71_RS11365	COG2816	NAD+ diphosphatase activity
G4G71_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS11400	COG0616	signal peptide processing
G4G71_RS11405	COG0604	alcohol dehydrogenase
G4G71_RS11430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4G71_RS11445	COG0534	Mate efflux family protein
G4G71_RS11495	COG3813	Protein conserved in bacteria
G4G71_RS11500	COG4977	sequence-specific DNA binding
G4G71_RS11510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS11535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4G71_RS11540	COG2866	Carboxypeptidase
G4G71_RS11595	COG2010	Cytochrome c
G4G71_RS11615	COG0583	DNA-binding transcription factor activity
G4G71_RS11620	COG3485	protocatechuate 3,4-dioxygenase
G4G71_RS11625	COG3485	protocatechuate 3,4-dioxygenase
G4G71_RS11630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G4G71_RS11635	COG1414	Transcriptional regulator
G4G71_RS11650	COG4948	Mandelate Racemase Muconate Lactonizing
G4G71_RS11655	COG4829	muconolactone delta-isomerase
G4G71_RS11660	COG3485	protocatechuate 3,4-dioxygenase
G4G71_RS11665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4G71_RS11670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4G71_RS11675	COG0183	Belongs to the thiolase family
G4G71_RS11685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G4G71_RS11690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G71_RS11695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4G71_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS11705	COG2610	gluconate transmembrane transporter activity
G4G71_RS11715	COG3290	protein histidine kinase activity
G4G71_RS11715	COG3829	transcription factor binding
G4G71_RS11735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4G71_RS11740	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS11745	COG0789	Transcriptional regulator
G4G71_RS11750	COG3284	Transcriptional regulator
G4G71_RS11755	COG1132	(ABC) transporter
G4G71_RS11775	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS11780	COG0583	DNA-binding transcription factor activity
G4G71_RS11790	COG2233	PERMEase
G4G71_RS11795	COG0583	DNA-binding transcription factor activity
G4G71_RS11810	COG1309	transcriptional regulator
G4G71_RS11825	COG0251	oxidation-reduction process
G4G71_RS11845	COG0154	amidase activity
G4G71_RS11870	COG0642	Histidine kinase
G4G71_RS11895	COG0477	Major facilitator Superfamily
G4G71_RS11925	COG4221	oxidoreductase activity
G4G71_RS11935	COG0183	Belongs to the thiolase family
G4G71_RS11945	COG1686	Belongs to the peptidase S11 family
G4G71_RS11950	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS11960	COG0840	transmembrane signaling receptor activity
G4G71_RS11965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4G71_RS11975	COG0183	Belongs to the thiolase family
G4G71_RS11980	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS12040	COG0729	surface antigen
G4G71_RS12050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4G71_RS12065	COG0667	Aldo Keto reductase
G4G71_RS12070	COG0583	DNA-binding transcription factor activity
G4G71_RS12095	COG2011	ABC-type metal ion transport system permease component
G4G71_RS12105	COG1464	Belongs to the NlpA lipoprotein family
G4G71_RS12130	COG2011	ABC-type metal ion transport system permease component
G4G71_RS12145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4G71_RS12155	COG3795	YCII-related domain
G4G71_RS12180	COG3123	guanosine phosphorylase activity
G4G71_RS12190	COG2084	Dehydrogenase
G4G71_RS12200	COG1501	Belongs to the glycosyl hydrolase 31 family
G4G71_RS12220	COG2009	succinate dehydrogenase
G4G71_RS12225	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G4G71_RS12230	COG1053	succinate dehydrogenase
G4G71_RS12235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G4G71_RS12320	COG2197	response regulator
G4G71_RS12325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS12325	COG2205	protein histidine kinase activity
G4G71_RS12345	COG5295	Hep Hag repeat protein
G4G71_RS12350	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4G71_RS12355	COG3119	arylsulfatase activity
G4G71_RS12370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G4G71_RS12375	COG2271	Major facilitator Superfamily
G4G71_RS12380	COG1609	Transcriptional regulator
G4G71_RS12385	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS12390	COG2909	trisaccharide binding
G4G71_RS12395	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS12400	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS12420	COG0183	Belongs to the thiolase family
G4G71_RS12425	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS12435	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G4G71_RS12440	COG1064	alcohol dehydrogenase
G4G71_RS12445	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS12455	COG1454	alcohol dehydrogenase
G4G71_RS12485	COG2030	dehydratase
G4G71_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS12530	COG3119	arylsulfatase activity
G4G71_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS12550	COG0183	Belongs to the thiolase family
G4G71_RS12555	COG1024	Enoyl-CoA hydratase
G4G71_RS12555	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS12560	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS12595	COG0517	IMP dehydrogenase activity
G4G71_RS12605	COG3278	Belongs to the heme-copper respiratory oxidase family
G4G71_RS12615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G71_RS12615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G71_RS12640	COG4206	TonB-dependent receptor
G4G71_RS12655	COG3501	Rhs element vgr protein
G4G71_RS12770	COG3459	Glycosyltransferase 36 associated
G4G71_RS12800	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS12825	COG3604	Transcriptional regulator
G4G71_RS12850	COG3712	iron ion homeostasis
G4G71_RS12855	COG1595	DNA-templated transcription, initiation
G4G71_RS12885	COG2851	Citrate transporter
G4G71_RS12905	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS12950	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4G71_RS12950	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS12960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4G71_RS12970	COG2226	methyltransferase
G4G71_RS12975	COG0531	amino acid
G4G71_RS12985	COG0583	DNA-binding transcription factor activity
G4G71_RS13000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS13005	COG0697	spore germination
G4G71_RS13010	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G4G71_RS13015	COG0768	penicillin binding
G4G71_RS13025	COG3383	formate dehydrogenase (NAD+) activity
G4G71_RS13070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS13100	COG3712	iron ion homeostasis
G4G71_RS13105	COG1595	DNA-templated transcription, initiation
G4G71_RS13120	COG1335	isochorismatase
G4G71_RS13125	COG0625	glutathione transferase activity
G4G71_RS13130	COG1129	ABC transporter
G4G71_RS13135	COG1172	Belongs to the binding-protein-dependent transport system permease family
G4G71_RS13155	COG0531	amino acid
G4G71_RS13190	COG2188	Transcriptional regulator
G4G71_RS13225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS13230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS13235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS13240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS13245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G4G71_RS13250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS13255	COG4206	TonB-dependent receptor
G4G71_RS13260	COG3191	aminopeptidase activity
G4G71_RS13270	COG0747	negative chemotaxis
G4G71_RS13280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4G71_RS13305	COG4251	negative regulation of phosphorylation
G4G71_RS13305	COG3706	GGDEF domain
G4G71_RS13305	COG2203	Gaf domain
G4G71_RS13305	COG5001	Diguanylate cyclase
G4G71_RS13315	COG3712	iron ion homeostasis
G4G71_RS13330	COG0583	DNA-binding transcription factor activity
G4G71_RS13340	COG3300	MHYT domain
G4G71_RS13340	COG5001	Diguanylate cyclase
G4G71_RS13350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4G71_RS13355	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS13360	COG0583	DNA-binding transcription factor activity
G4G71_RS13365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4G71_RS13370	COG2207	Transcriptional regulator
G4G71_RS13385	COG0477	Major facilitator Superfamily
G4G71_RS13410	COG0174	glutamine synthetase
G4G71_RS13420	COG0531	amino acid
G4G71_RS13430	COG2423	ornithine cyclodeaminase activity
G4G71_RS13440	COG1473	amidohydrolase
G4G71_RS13455	COG0625	glutathione transferase activity
G4G71_RS13480	COG1278	Cold shock
G4G71_RS13485	COG2204	response regulator
G4G71_RS13495	COG2837	iron assimilation
G4G71_RS13500	COG0583	DNA-binding transcription factor activity
G4G71_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS13510	COG4106	trans-aconitate 2-methyltransferase activity
G4G71_RS13575	COG0583	DNA-binding transcription factor activity
G4G71_RS13645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G71_RS13660	COG0583	DNA-binding transcription factor activity
G4G71_RS13670	COG2223	nitrite transmembrane transporter activity
G4G71_RS13685	COG2365	Tyrosine phosphatase family
G4G71_RS13710	COG3791	Glutathione-dependent formaldehyde-activating
G4G71_RS13725	COG0531	amino acid
G4G71_RS13790	COG1959	2 iron, 2 sulfur cluster binding
G4G71_RS13805	COG1285	pathogenesis
G4G71_RS13825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G4G71_RS13845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS13855	COG0174	glutamine synthetase
G4G71_RS13870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS13875	COG1126	abc transporter atp-binding protein
G4G71_RS13885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS13900	COG3437	response regulator, receiver
G4G71_RS13955	COG0668	transmembrane transport
G4G71_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS13975	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G71_RS13980	COG0477	Major facilitator Superfamily
G4G71_RS13995	COG0697	spore germination
G4G71_RS14010	COG1191	sigma factor activity
G4G71_RS14050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS14100	COG1733	regulation of RNA biosynthetic process
G4G71_RS14105	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G4G71_RS14105	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G4G71_RS14105	COG0506	proline dehydrogenase activity
G4G71_RS14115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS14125	COG1335	isochorismatase
G4G71_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS14145	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS14155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS14160	COG0477	Major facilitator Superfamily
G4G71_RS14180	COG0385	Bile acid
G4G71_RS14200	COG0417	DNA replication proofreading
G4G71_RS14205	COG0720	synthase
G4G71_RS14220	COG3604	Transcriptional regulator
G4G71_RS14255	COG0745	RESPONSE REGULATOR receiver
G4G71_RS14260	COG2205	protein histidine kinase activity
G4G71_RS14265	COG0840	transmembrane signaling receptor activity
G4G71_RS14270	COG2056	Na+-H+ antiporter family
G4G71_RS14295	COG0713	ATP synthesis coupled electron transport
G4G71_RS14310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G4G71_RS14365	COG2153	protein acetylation
G4G71_RS14370	COG2850	peptidyl-arginine hydroxylation
G4G71_RS14385	COG0482	sulfurtransferase activity
G4G71_RS14405	COG1278	Cold shock
G4G71_RS14410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G4G71_RS14415	COG0542	response to heat
G4G71_RS14420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G4G71_RS14435	COG0492	ferredoxin-NADP+ reductase activity
G4G71_RS14450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G4G71_RS14470	COG0435	Glutathione S-transferase
G4G71_RS14475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G4G71_RS14575	COG0270	DNA (cytosine-5-)-methyltransferase activity
G4G71_RS14590	COG5645	(Lipo)protein
G4G71_RS14645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4G71_RS14690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4G71_RS14720	COG1522	sequence-specific DNA binding
G4G71_RS14730	COG2356	endonuclease I
G4G71_RS14755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G4G71_RS14760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4G71_RS14765	COG3781	membrane
G4G71_RS14780	COG0583	DNA-binding transcription factor activity
G4G71_RS14785	COG0217	transcriptional regulatory protein
G4G71_RS14795	COG1595	DNA-templated transcription, initiation
G4G71_RS14800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS14805	COG0235	Class ii aldolase
G4G71_RS14840	COG1566	PFAM secretion protein HlyD family protein
G4G71_RS14850	COG1289	transmembrane transporter activity
G4G71_RS14855	COG0583	DNA-binding transcription factor activity
G4G71_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS14865	COG1063	alcohol dehydrogenase
G4G71_RS14870	COG0656	L-ascorbic acid biosynthetic process
G4G71_RS14875	COG2814	Major facilitator Superfamily
G4G71_RS14885	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS14885	COG2030	dehydratase
G4G71_RS14890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4G71_RS14895	COG2151	metal-sulfur cluster biosynthetic enzyme
G4G71_RS14900	COG3396	Phenylacetate-CoA oxygenase
G4G71_RS14905	COG3460	Phenylacetate-CoA oxygenase
G4G71_RS14910	COG3396	Phenylacetate-CoA oxygenase
G4G71_RS14915	COG5507	3-demethylubiquinone-9 3-methyltransferase
G4G71_RS14930	COG0183	Belongs to the thiolase family
G4G71_RS14935	COG2050	protein possibly involved in aromatic compounds catabolism
G4G71_RS14940	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS14945	COG1024	Enoyl-CoA hydratase
G4G71_RS14950	COG1024	Enoyl-CoA hydratase
G4G71_RS14960	COG3327	negative regulation of DNA-templated transcription, initiation
G4G71_RS14965	COG2207	Transcriptional regulator
G4G71_RS14970	COG3474	cytochrome
G4G71_RS14975	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS14990	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G4G71_RS15005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4G71_RS15010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4G71_RS15020	COG2031	fatty acid transporter
G4G71_RS15055	COG2205	protein histidine kinase activity
G4G71_RS15055	COG0784	Response regulator, receiver
G4G71_RS15080	COG1131	(ABC) transporter
G4G71_RS15100	COG3851	Histidine kinase
G4G71_RS15115	COG0189	ligase activity
G4G71_RS15155	COG1968	undecaprenyl-diphosphatase activity
G4G71_RS15160	COG1278	Cold shock
G4G71_RS15165	COG0583	DNA-binding transcription factor activity
G4G71_RS15180	COG0488	(ABC) transporter
G4G71_RS15215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4G71_RS15240	COG1115	amino acid carrier protein
G4G71_RS15245	COG0252	asparaginase activity
G4G71_RS15250	COG4566	intracellular signal transduction
G4G71_RS15260	COG3485	protocatechuate 3,4-dioxygenase
G4G71_RS15275	COG4774	siderophore transport
G4G71_RS15310	COG1120	ATPase activity
G4G71_RS15315	COG0210	DNA helicase
G4G71_RS15335	COG0583	DNA-binding transcription factor activity
G4G71_RS15360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4G71_RS15365	COG1126	abc transporter atp-binding protein
G4G71_RS15370	COG0765	amino acid transport
G4G71_RS15380	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4G71_RS15385	COG0583	DNA-binding transcription factor activity
G4G71_RS15425	COG1917	Cupin 2, conserved barrel domain protein
G4G71_RS15425	COG4977	sequence-specific DNA binding
G4G71_RS15445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS15450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS15455	COG0765	amino acid transport
G4G71_RS15460	COG4160	amino acid transport
G4G71_RS15470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS15475	COG0667	Aldo Keto reductase
G4G71_RS15480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS15490	COG1609	Transcriptional regulator
G4G71_RS15505	COG3729	General stress protein
G4G71_RS15530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS15535	COG1045	serine acetyltransferase
G4G71_RS15540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4G71_RS15615	COG1640	4-alpha-glucanotransferase
G4G71_RS15640	COG3568	Endonuclease Exonuclease Phosphatase
G4G71_RS15645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4G71_RS15650	COG0392	lysyltransferase activity
G4G71_RS15660	COG0366	Alpha amylase catalytic
G4G71_RS15680	COG1285	pathogenesis
G4G71_RS15690	COG0058	SHG alpha-glucan phosphorylase activity
G4G71_RS15725	COG1595	DNA-templated transcription, initiation
G4G71_RS15730	COG3712	iron ion homeostasis
G4G71_RS15745	COG4176	ABC-type proline glycine betaine transport system permease component
G4G71_RS15760	COG2301	Belongs to the HpcH HpaI aldolase family
G4G71_RS15770	COG2079	MmgE PrpD family protein
G4G71_RS15775	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS15780	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G4G71_RS15800	COG0300	oxidoreductase activity
G4G71_RS15805	COG2207	Transcriptional regulator
G4G71_RS15810	COG2207	Transcriptional regulator
G4G71_RS15835	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G4G71_RS15840	COG2197	response regulator
G4G71_RS15845	COG2271	Major facilitator Superfamily
G4G71_RS15855	COG2508	Transcriptional regulator
G4G71_RS15865	COG0579	oxidoreductase
G4G71_RS15880	COG4772	TonB-dependent receptor
G4G71_RS15905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4G71_RS15910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4G71_RS15925	COG0840	transmembrane signaling receptor activity
G4G71_RS15965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G4G71_RS15970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4G71_RS15975	COG1309	transcriptional regulator
G4G71_RS15995	COG2837	iron assimilation
G4G71_RS16000	COG0586	Pfam SNARE associated Golgi protein
G4G71_RS16010	COG3706	GGDEF domain
G4G71_RS16025	COG5002	protein histidine kinase activity
G4G71_RS16035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G4G71_RS16040	COG0784	Response regulator, receiver
G4G71_RS16040	COG2198	Histidine kinase
G4G71_RS16040	COG2205	protein histidine kinase activity
G4G71_RS16055	COG5002	protein histidine kinase activity
G4G71_RS16080	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
G4G71_RS16085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G4G71_RS16095	COG3284	Transcriptional regulator
G4G71_RS16100	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS16110	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS16135	COG4993	Dehydrogenase
G4G71_RS16135	COG2010	Cytochrome c
G4G71_RS16150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G71_RS16155	COG0402	S-adenosylhomocysteine deaminase activity
G4G71_RS16165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G71_RS16180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G4G71_RS16195	COG1609	Transcriptional regulator
G4G71_RS16200	COG3265	gluconokinase activity
G4G71_RS16215	COG0251	oxidation-reduction process
G4G71_RS16255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G4G71_RS16265	COG0581	inorganic phosphate transmembrane transporter activity
G4G71_RS16270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4G71_RS16290	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS16305	COG3038	cytochrome b561
G4G71_RS16310	COG0753	catalase activity
G4G71_RS16315	COG1595	DNA-templated transcription, initiation
G4G71_RS16330	COG3224	Antibiotic biosynthesis monooxygenase
G4G71_RS16340	COG3468	outer membrane autotransporter barrel domain protein
G4G71_RS16345	COG0826	peptidase U32
G4G71_RS16355	COG2808	Putative FMN-binding domain
G4G71_RS16360	COG4251	negative regulation of phosphorylation
G4G71_RS16360	COG5001	Diguanylate cyclase
G4G71_RS16360	COG2203	Gaf domain
G4G71_RS16360	COG3706	GGDEF domain
G4G71_RS16365	COG5001	Diguanylate cyclase
G4G71_RS16365	COG4251	negative regulation of phosphorylation
G4G71_RS16365	COG3706	GGDEF domain
G4G71_RS16365	COG2203	Gaf domain
G4G71_RS16370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4G71_RS16395	COG0583	DNA-binding transcription factor activity
G4G71_RS16400	COG0789	Transcriptional regulator
G4G71_RS16405	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4G71_RS16420	COG0596	Alpha beta hydrolase
G4G71_RS16445	COG0183	Belongs to the thiolase family
G4G71_RS16450	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS16455	COG1024	Enoyl-CoA hydratase
G4G71_RS16465	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS16470	COG2814	Major facilitator Superfamily
G4G71_RS16485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G4G71_RS16490	COG3387	PFAM Glycoside hydrolase 15-related
G4G71_RS16495	COG1877	trehalose-phosphatase activity
G4G71_RS16500	COG5001	Diguanylate cyclase
G4G71_RS16500	COG3300	MHYT domain
G4G71_RS16525	COG1064	alcohol dehydrogenase
G4G71_RS16530	COG0667	Aldo Keto reductase
G4G71_RS16540	COG0667	Aldo Keto reductase
G4G71_RS16545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G71_RS16550	COG0477	Major facilitator Superfamily
G4G71_RS16565	COG2258	MOSC domain
G4G71_RS16570	COG0697	spore germination
G4G71_RS16575	COG0583	DNA-binding transcription factor activity
G4G71_RS16600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4G71_RS16600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4G71_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS16630	COG1942	4-Oxalocrotonate Tautomerase
G4G71_RS16635	COG2814	Major facilitator Superfamily
G4G71_RS16645	COG2197	response regulator
G4G71_RS16660	COG0659	secondary active sulfate transmembrane transporter activity
G4G71_RS16670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS16675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G71_RS16705	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS16750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS16755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G71_RS16765	COG4991	sh3 domain protein
G4G71_RS16800	COG2188	Transcriptional regulator
G4G71_RS16805	COG1053	succinate dehydrogenase
G4G71_RS16820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS16840	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS16905	COG0583	DNA-binding transcription factor activity
G4G71_RS16910	COG3811	Belongs to the UPF0386 family
G4G71_RS16930	COG0584	glycerophosphoryl diester phosphodiesterase
G4G71_RS16935	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G4G71_RS16940	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G4G71_RS16950	COG3224	Antibiotic biosynthesis monooxygenase
G4G71_RS16965	COG1335	isochorismatase
G4G71_RS16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS17015	COG0579	oxidoreductase
G4G71_RS17050	COG0667	Aldo Keto reductase
G4G71_RS17055	COG1595	DNA-templated transcription, initiation
G4G71_RS17060	COG3712	iron ion homeostasis
G4G71_RS17090	COG1119	ATPase activity
G4G71_RS17100	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17105	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17115	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS17120	COG2197	response regulator
G4G71_RS17140	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS17145	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS17150	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17155	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS17160	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS17175	COG0183	Belongs to the thiolase family
G4G71_RS17190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G4G71_RS17195	COG2909	trisaccharide binding
G4G71_RS17200	COG1024	Enoyl-CoA hydratase
G4G71_RS17205	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17210	COG0183	Belongs to the thiolase family
G4G71_RS17215	COG2030	dehydratase
G4G71_RS17230	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G4G71_RS17245	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17275	COG1473	amidohydrolase
G4G71_RS17280	COG0583	DNA-binding transcription factor activity
G4G71_RS17295	COG2843	Capsule synthesis protein
G4G71_RS17330	COG3842	ATPase activity
G4G71_RS17335	COG1177	transmembrane transport
G4G71_RS17340	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS17375	COG1595	DNA-templated transcription, initiation
G4G71_RS17385	COG4774	siderophore transport
G4G71_RS17400	COG0640	Transcriptional regulator
G4G71_RS17410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4G71_RS17415	COG0431	NADPH-dependent FMN reductase
G4G71_RS17425	COG0477	Major facilitator Superfamily
G4G71_RS17440	COG0583	DNA-binding transcription factor activity
G4G71_RS17445	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS17455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS17480	COG0006	proline dipeptidase activity
G4G71_RS17500	COG3842	ATPase activity
G4G71_RS17505	COG0583	DNA-binding transcription factor activity
G4G71_RS17535	COG2207	Transcriptional regulator
G4G71_RS17565	COG3246	L-lysine catabolic process to acetate
G4G71_RS17570	COG2175	clavaminate synthase activity
G4G71_RS17580	COG1566	PFAM secretion protein HlyD family protein
G4G71_RS17600	COG1999	signal sequence binding
G4G71_RS17620	COG1131	(ABC) transporter
G4G71_RS17625	COG0842	Transport permease protein
G4G71_RS17630	COG0842	Transport permease protein
G4G71_RS17650	COG4319	ketosteroid isomerase
G4G71_RS17685	COG0587	DNA-directed DNA polymerase activity
G4G71_RS17695	COG0583	DNA-binding transcription factor activity
G4G71_RS17700	COG0019	diaminopimelate decarboxylase activity
G4G71_RS17715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G71_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS17745	COG4638	Rieske (2fe-2S)
G4G71_RS17750	COG0154	amidase activity
G4G71_RS17765	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS17780	COG1595	DNA-templated transcription, initiation
G4G71_RS17855	COG2807	transmembrane transport
G4G71_RS17860	COG0590	tRNA wobble adenosine to inosine editing
G4G71_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS17900	COG0583	DNA-binding transcription factor activity
G4G71_RS17920	COG0583	DNA-binding transcription factor activity
G4G71_RS17925	COG0504	CTP synthase activity
G4G71_RS17930	COG2329	Antibiotic biosynthesis monooxygenase
G4G71_RS17945	COG0791	NLP P60 protein
G4G71_RS17950	COG0791	NLP P60 protein
G4G71_RS17960	COG1538	Outer membrane efflux protein
G4G71_RS17965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G71_RS17970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G71_RS17975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS18005	COG1944	ATP diphosphatase activity
G4G71_RS18010	COG2081	HI0933 family
G4G71_RS18025	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G4G71_RS18030	COG4638	Rieske (2fe-2S)
G4G71_RS18040	COG0583	DNA-binding transcription factor activity
G4G71_RS18045	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS18150	COG0583	DNA-binding transcription factor activity
G4G71_RS18170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS18175	COG1595	DNA-templated transcription, initiation
G4G71_RS18185	COG4771	TonB-dependent receptor
G4G71_RS18195	COG2832	Protein of unknown function (DUF454)
G4G71_RS18205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS18210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4G71_RS18220	COG1309	transcriptional regulator
G4G71_RS18240	COG1522	sequence-specific DNA binding
G4G71_RS18260	COG1741	Belongs to the pirin family
G4G71_RS18270	COG2080	2 iron, 2 sulfur cluster binding
G4G71_RS18275	COG2010	Cytochrome c
G4G71_RS18275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G4G71_RS18280	COG2010	Cytochrome c
G4G71_RS18280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G4G71_RS18320	COG4944	Protein of unknown function (DUF1109)
G4G71_RS18325	COG1595	DNA-templated transcription, initiation
G4G71_RS18335	COG3220	belongs to the UPF0276 family
G4G71_RS18355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G4G71_RS18365	COG3008	intermembrane lipid transfer
G4G71_RS18370	COG2995	paraquat-inducible protein a
G4G71_RS18380	COG2985	domain, Protein
G4G71_RS18395	COG3119	arylsulfatase activity
G4G71_RS18410	COG2304	oxidoreductase activity
G4G71_RS18430	COG0714	Associated with various cellular activities
G4G71_RS18485	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G4G71_RS18505	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G4G71_RS18510	COG1063	alcohol dehydrogenase
G4G71_RS18525	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS18535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4G71_RS18545	COG0596	Alpha beta hydrolase
G4G71_RS18555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS18565	COG0747	negative chemotaxis
G4G71_RS18575	COG1368	sulfuric ester hydrolase activity
G4G71_RS18585	COG0583	DNA-binding transcription factor activity
G4G71_RS18595	COG1064	alcohol dehydrogenase
G4G71_RS18625	COG0583	DNA-binding transcription factor activity
G4G71_RS18630	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G4G71_RS18635	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G4G71_RS18655	COG0583	DNA-binding transcription factor activity
G4G71_RS18665	COG2831	hemolysin activation secretion protein
G4G71_RS18670	COG2994	toxin metabolic process
G4G71_RS18675	COG3210	domain, Protein
G4G71_RS18720	COG1335	isochorismatase
G4G71_RS18725	COG1335	isochorismatase
G4G71_RS18735	COG0583	DNA-binding transcription factor activity
G4G71_RS18740	COG0494	nUDIX hydrolase
G4G71_RS18770	COG3706	GGDEF domain
G4G71_RS18770	COG4251	negative regulation of phosphorylation
G4G71_RS18770	COG5001	Diguanylate cyclase
G4G71_RS18770	COG2203	Gaf domain
G4G71_RS18820	COG0174	glutamine synthetase
G4G71_RS18825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS18830	COG0583	DNA-binding transcription factor activity
G4G71_RS18835	COG3842	ATPase activity
G4G71_RS18845	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS18850	COG1177	transmembrane transport
G4G71_RS18880	COG0840	transmembrane signaling receptor activity
G4G71_RS18895	COG3278	Belongs to the heme-copper respiratory oxidase family
G4G71_RS18915	COG3278	Belongs to the heme-copper respiratory oxidase family
G4G71_RS18930	COG2010	Cytochrome c
G4G71_RS18935	COG0348	domain, Protein
G4G71_RS18970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4G71_RS18990	COG1294	oxidase, subunit
G4G71_RS18995	COG4890	Cyd operon protein YbgT
G4G71_RS19040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4G71_RS19055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G4G71_RS19095	COG1196	nuclear chromosome segregation
G4G71_RS19125	COG0402	S-adenosylhomocysteine deaminase activity
G4G71_RS19160	COG2252	PERMEase
G4G71_RS19165	COG2197	response regulator
G4G71_RS19195	COG2233	PERMEase
G4G71_RS19205	COG0840	transmembrane signaling receptor activity
G4G71_RS19230	COG0745	RESPONSE REGULATOR receiver
G4G71_RS19235	COG2853	Lipoprotein
G4G71_RS19270	COG2132	Multicopper oxidase
G4G71_RS19290	COG0842	Transport permease protein
G4G71_RS19295	COG1131	(ABC) transporter
G4G71_RS19300	COG0625	glutathione transferase activity
G4G71_RS19365	COG1956	GAF domain-containing protein
G4G71_RS19380	COG1846	Transcriptional regulator
G4G71_RS19385	COG0386	Belongs to the glutathione peroxidase family
G4G71_RS19395	COG0436	Aminotransferase
G4G71_RS19410	COG0500	methyltransferase
G4G71_RS19420	COG3384	dioxygenase
G4G71_RS19425	COG0513	Belongs to the DEAD box helicase family
G4G71_RS19430	COG1024	Enoyl-CoA hydratase
G4G71_RS19450	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G4G71_RS19455	COG0501	Belongs to the peptidase M48B family
G4G71_RS19460	COG3214	Protein conserved in bacteria
G4G71_RS19475	COG0583	DNA-binding transcription factor activity
G4G71_RS19480	COG0730	response to heat
G4G71_RS19490	COG1846	Transcriptional regulator
G4G71_RS19495	COG1764	response to oxidative stress
G4G71_RS19535	COG4181	ATPase activity
G4G71_RS19540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G4G71_RS19550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4G71_RS19595	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G4G71_RS19600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G71_RS19615	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS19630	COG4447	cellulose binding
G4G71_RS19645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4G71_RS19765	COG0210	DNA helicase
G4G71_RS19790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G4G71_RS19825	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G4G71_RS19830	COG0583	DNA-binding transcription factor activity
G4G71_RS19835	COG2855	membrane
G4G71_RS19840	COG2259	Doxx family
G4G71_RS19845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G4G71_RS19850	COG0084	hydrolase, TatD family'
G4G71_RS19895	COG0714	Associated with various cellular activities
G4G71_RS19900	COG0583	DNA-binding transcription factor activity
G4G71_RS19920	COG5002	protein histidine kinase activity
G4G71_RS19920	COG5002	protein histidine kinase activity
G4G71_RS19930	COG4303	Ethanolamine ammonia lyase large subunit
G4G71_RS19935	COG4302	ethanolamine ammonia-lyase activity
G4G71_RS19950	COG1309	transcriptional regulator
G4G71_RS19965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4G71_RS19970	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS19975	COG1024	Enoyl-CoA hydratase
G4G71_RS19990	COG0318	PFAM AMP-dependent synthetase and ligase
G4G71_RS20005	COG1595	DNA-templated transcription, initiation
G4G71_RS20010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS20035	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4G71_RS20035	COG0596	Alpha beta hydrolase
G4G71_RS20075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G4G71_RS20090	COG0084	hydrolase, TatD family'
G4G71_RS20110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4G71_RS20120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4G71_RS20145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G4G71_RS20150	COG1399	metal-binding, possibly nucleic acid-binding protein
G4G71_RS20160	COG0616	signal peptide processing
G4G71_RS20160	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G4G71_RS20165	COG0546	phosphoglycolate phosphatase activity
G4G71_RS20175	COG1530	ribonuclease E activity
G4G71_RS20185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4G71_RS20190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G4G71_RS20195	COG2835	tetraacyldisaccharide 4'-kinase activity
G4G71_RS20205	COG0848	biopolymer transport protein
G4G71_RS20210	COG0811	peptide transport
G4G71_RS20215	COG0658	competence protein
G4G71_RS20215	COG2333	competence protein COMEC
G4G71_RS20235	COG4591	ABC-type transport system involved in lipoprotein release permease component
G4G71_RS20250	COG0584	glycerophosphoryl diester phosphodiesterase
G4G71_RS20260	COG1477	protein flavinylation
G4G71_RS20265	COG1113	amino acid transport
G4G71_RS20275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G4G71_RS20295	COG1376	ErfK ybiS ycfS ynhG family protein
G4G71_RS20355	COG0589	response to stress
G4G71_RS20370	COG0741	lytic transglycosylase activity
G4G71_RS20385	COG0835	chemotaxis
G4G71_RS20385	COG0784	Response regulator, receiver
G4G71_RS20395	COG1070	Carbohydrate kinase
G4G71_RS20420	COG0521	Mo-molybdopterin cofactor biosynthetic process
G4G71_RS20440	COG2084	Dehydrogenase
G4G71_RS20450	COG1309	transcriptional regulator
G4G71_RS20455	COG0625	glutathione transferase activity
G4G71_RS20460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G71_RS20470	COG0004	ammonium transporteR
G4G71_RS20490	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G4G71_RS20500	COG2205	protein histidine kinase activity
G4G71_RS20500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4G71_RS20505	COG2197	response regulator
G4G71_RS20510	COG2205	protein histidine kinase activity
G4G71_RS20510	COG0784	Response regulator, receiver
G4G71_RS20510	COG2198	Histidine kinase
G4G71_RS20515	COG3171	Protein conserved in bacteria
G4G71_RS20520	COG2027	D-alanyl-D-alanine carboxypeptidase
G4G71_RS20535	COG3130	regulation of translation
G4G71_RS20585	COG0714	Associated with various cellular activities
G4G71_RS20650	COG0308	aminopeptidase N
G4G71_RS20660	COG3139	Protein of unknown function (DUF1315)
G4G71_RS20670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G4G71_RS20695	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4G71_RS20695	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS20740	COG1286	toxin biosynthetic process
G4G71_RS20745	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G4G71_RS20750	COG0285	dihydrofolate synthase activity
G4G71_RS20760	COG0135	phosphoribosylanthranilate isomerase activity
G4G71_RS20795	COG2226	methyltransferase
G4G71_RS20800	COG0066	3-isopropylmalate dehydratase activity
G4G71_RS20805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G4G71_RS20830	COG0251	oxidation-reduction process
G4G71_RS20835	COG3949	Membrane
G4G71_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS20860	COG0800	Aldolase
G4G71_RS20865	COG0596	Alpha beta hydrolase
G4G71_RS20900	COG0583	DNA-binding transcription factor activity
G4G71_RS20930	COG1555	photosystem II stabilization
G4G71_RS20940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4G71_RS20950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G4G71_RS20965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G4G71_RS20990	COG1132	(ABC) transporter
G4G71_RS21015	COG0242	peptide deformylase activity
G4G71_RS21035	COG2996	Protein conserved in bacteria
G4G71_RS21040	COG1132	(ABC) transporter
G4G71_RS21050	COG0628	permease
G4G71_RS21065	COG1187	pseudouridine synthase activity
G4G71_RS21075	COG1024	Enoyl-CoA hydratase
G4G71_RS21150	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4G71_RS21165	COG0835	chemotaxis
G4G71_RS21175	COG1192	Involved in chromosome partitioning
G4G71_RS21185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4G71_RS21195	COG2198	Histidine kinase
G4G71_RS21195	COG0784	Response regulator, receiver
G4G71_RS21195	COG0643	Histidine kinase
G4G71_RS21225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4G71_RS21230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G4G71_RS21255	COG1987	bacterial-type flagellum assembly
G4G71_RS21295	COG0745	RESPONSE REGULATOR receiver
G4G71_RS21310	COG2207	Transcriptional regulator
G4G71_RS21315	COG1280	lysine exporter protein (LysE YggA)
G4G71_RS21365	COG3852	Histidine kinase
G4G71_RS21395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4G71_RS21400	COG0457	Tetratricopeptide repeat
G4G71_RS21400	COG0859	PFAM glycosyl transferase family 9
G4G71_RS21420	COG1256	bacterial-type flagellum assembly
G4G71_RS21445	COG4786	Flagellar basal body rod
G4G71_RS21465	COG1815	bacterial-type flagellum-dependent cell motility
G4G71_RS21475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G4G71_RS21480	COG1215	transferase activity, transferring glycosyl groups
G4G71_RS21495	COG3706	GGDEF domain
G4G71_RS21520	COG2239	Acts as a magnesium transporter
G4G71_RS21555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G4G71_RS21650	COG0583	DNA-binding transcription factor activity
G4G71_RS21675	COG0513	Belongs to the DEAD box helicase family
G4G71_RS21680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4G71_RS21690	COG0791	NLP P60 protein
G4G71_RS21715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G4G71_RS21725	COG0529	Catalyzes the synthesis of activated sulfate
G4G71_RS21750	COG0402	S-adenosylhomocysteine deaminase activity
G4G71_RS21755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4G71_RS21765	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS21770	COG3706	GGDEF domain
G4G71_RS21785	COG3278	Belongs to the heme-copper respiratory oxidase family
G4G71_RS21805	COG0121	glutamine amidotransferase
G4G71_RS21820	COG1770	oligopeptidase
G4G71_RS21830	COG2983	Belongs to the UPF0260 family
G4G71_RS21845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4G71_RS21905	COG3122	Protein conserved in bacteria
G4G71_RS21915	COG3956	TIGRFAM MazG family protein
G4G71_RS21920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4G71_RS21945	COG0784	Response regulator, receiver
G4G71_RS21945	COG5002	protein histidine kinase activity
G4G71_RS21945	COG2205	protein histidine kinase activity
G4G71_RS21950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4G71_RS21965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4G71_RS21985	COG0392	lysyltransferase activity
G4G71_RS21985	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G4G71_RS21995	COG3038	cytochrome b561
G4G71_RS22020	COG2207	Transcriptional regulator
G4G71_RS22025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4G71_RS22045	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4G71_RS22055	COG1846	Transcriptional regulator
G4G71_RS22065	COG3706	GGDEF domain
G4G71_RS22065	COG2203	Gaf domain
G4G71_RS22065	COG5001	Diguanylate cyclase
G4G71_RS22065	COG4251	negative regulation of phosphorylation
G4G71_RS22075	COG0514	ATP-dependent DNA helicase (RecQ)
G4G71_RS22085	COG2832	Protein of unknown function (DUF454)
G4G71_RS22100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4G71_RS22105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS22115	COG5001	Diguanylate cyclase
G4G71_RS22115	COG3300	MHYT domain
G4G71_RS22240	COG1783	phage Terminase large subunit
G4G71_RS22320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4G71_RS22400	COG3723	Recombinational DNA repair protein, rece pathway
G4G71_RS22500	COG0215	cysteine-tRNA ligase activity
G4G71_RS22505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G4G71_RS22510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G4G71_RS22530	COG0589	response to stress
G4G71_RS22550	COG2197	response regulator
G4G71_RS22565	COG2223	nitrite transmembrane transporter activity
G4G71_RS22570	COG0515	serine threonine protein kinase
G4G71_RS22575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4G71_RS22580	COG2146	nitrite reductase [NAD(P)H] activity
G4G71_RS22585	COG0243	molybdopterin cofactor binding
G4G71_RS22605	COG0668	transmembrane transport
G4G71_RS22640	COG3064	Membrane
G4G71_RS22650	COG4067	protein conserved in archaea
G4G71_RS22650	COG0189	ligase activity
G4G71_RS22660	COG0189	ligase activity
G4G71_RS22690	COG2909	trisaccharide binding
G4G71_RS22695	COG2909	trisaccharide binding
G4G71_RS22735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4G71_RS22780	COG0598	Magnesium transport protein CorA
G4G71_RS22785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G4G71_RS22785	COG0519	Catalyzes the synthesis of GMP from XMP
G4G71_RS22790	COG1335	isochorismatase
G4G71_RS22795	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4G71_RS22795	COG1024	Enoyl-CoA hydratase
G4G71_RS22800	COG0183	Belongs to the thiolase family
G4G71_RS22825	COG2308	Evidence 4 Homologs of previously reported genes of
G4G71_RS22830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G4G71_RS22835	COG3842	ATPase activity
G4G71_RS22840	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS22845	COG1177	transmembrane transport
G4G71_RS22850	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS22855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G4G71_RS22855	COG0519	Catalyzes the synthesis of GMP from XMP
G4G71_RS22870	COG0300	oxidoreductase activity
G4G71_RS22890	COG0730	response to heat
G4G71_RS22915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4G71_RS22955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G4G71_RS22960	COG1073	alpha beta
G4G71_RS23005	COG0625	glutathione transferase activity
G4G71_RS23010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS23030	COG3135	benzoate transporter
G4G71_RS23050	COG2130	NADP-dependent
G4G71_RS23070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4G71_RS23100	COG0745	RESPONSE REGULATOR receiver
G4G71_RS23105	COG2205	protein histidine kinase activity
G4G71_RS23130	COG0745	RESPONSE REGULATOR receiver
G4G71_RS23135	COG2205	protein histidine kinase activity
G4G71_RS23145	COG2186	Transcriptional regulator
G4G71_RS23150	COG2807	transmembrane transport
G4G71_RS23155	COG0628	permease
G4G71_RS23175	COG1280	lysine exporter protein (LysE YggA)
G4G71_RS23190	COG1022	Amp-dependent synthetase and ligase
G4G71_RS23220	COG5002	protein histidine kinase activity
G4G71_RS23220	COG2205	protein histidine kinase activity
G4G71_RS23220	COG0784	Response regulator, receiver
G4G71_RS23345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS23350	COG2116	formate transmembrane transporter activity
G4G71_RS23375	COG1309	transcriptional regulator
G4G71_RS23385	COG3960	tartronate-semialdehyde synthase activity
G4G71_RS23390	COG3622	Belongs to the hyi family
G4G71_RS23395	COG2084	Dehydrogenase
G4G71_RS23405	COG0469	pyruvate kinase activity
G4G71_RS23410	COG4413	Urea transporter
G4G71_RS23415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G4G71_RS23425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4G71_RS23435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G4G71_RS23475	COG2205	protein histidine kinase activity
G4G71_RS23480	COG0745	RESPONSE REGULATOR receiver
G4G71_RS23490	COG4459	periplasmic nitrate reductase
G4G71_RS23495	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
G4G71_RS23495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G4G71_RS23500	COG3062	negative regulation of establishment of protein localization
G4G71_RS23515	COG3005	denitrification pathway
G4G71_RS23520	COG2951	lytic endotransglycosylase activity
G4G71_RS23545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G4G71_RS23565	COG2205	protein histidine kinase activity
G4G71_RS23570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4G71_RS23575	COG0745	RESPONSE REGULATOR receiver
G4G71_RS23580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4G71_RS23580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G4G71_RS23585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4G71_RS23605	COG1335	isochorismatase
G4G71_RS23625	COG0583	DNA-binding transcription factor activity
G4G71_RS23630	COG3257	ureidoglycine aminohydrolase activity
G4G71_RS23645	COG2203	Gaf domain
G4G71_RS23645	COG3706	GGDEF domain
G4G71_RS23645	COG4251	negative regulation of phosphorylation
G4G71_RS23645	COG5001	Diguanylate cyclase
G4G71_RS23650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4G71_RS23655	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4G71_RS23660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4G71_RS23670	COG2197	response regulator
G4G71_RS23675	COG0784	Response regulator, receiver
G4G71_RS23675	COG2205	protein histidine kinase activity
G4G71_RS23675	COG5002	protein histidine kinase activity
G4G71_RS23695	COG0583	DNA-binding transcription factor activity
G4G71_RS23705	COG1295	ribonuclease BN
G4G71_RS23725	COG0676	glucose-6-phosphate 1-epimerase activity
G4G71_RS23735	COG3842	ATPase activity
G4G71_RS23740	COG0395	ABC-type sugar transport system, permease component
G4G71_RS23745	COG1175	transmembrane transport
G4G71_RS23750	COG1653	transport
G4G71_RS23755	COG2852	Protein conserved in bacteria
G4G71_RS23760	COG2205	protein histidine kinase activity
G4G71_RS23765	COG0745	RESPONSE REGULATOR receiver
G4G71_RS23800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G4G71_RS23810	COG0180	Tryptophanyl-tRNA synthetase
G4G71_RS23815	COG0009	L-threonylcarbamoyladenylate synthase
G4G71_RS23820	COG0613	PHP domain protein
G4G71_RS23825	COG2917	probably involved in intracellular septation
G4G71_RS23830	COG2350	Protein conserved in bacteria
G4G71_RS23840	COG0745	RESPONSE REGULATOR receiver
G4G71_RS23845	COG3678	ATP-independent chaperone mediated protein folding
G4G71_RS23860	COG0778	Nitroreductase
G4G71_RS23865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4G71_RS23885	COG1201	RNA secondary structure unwinding
G4G71_RS23900	COG0784	Response regulator, receiver
G4G71_RS23900	COG0835	chemotaxis
G4G71_RS23920	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
G4G71_RS23925	COG0477	Major facilitator Superfamily
G4G71_RS23935	COG0306	phosphate transporter
G4G71_RS23960	COG3971	2-oxopent-4-enoate hydratase activity
G4G71_RS23965	COG0583	DNA-binding transcription factor activity
G4G71_RS23970	COG3180	Ammonia monooxygenase
G4G71_RS23995	COG4221	oxidoreductase activity
G4G71_RS24000	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4G71_RS24000	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS24010	COG2186	Transcriptional regulator
G4G71_RS24015	COG0277	FAD linked oxidase domain protein
G4G71_RS24020	COG0277	FAD linked oxidase domain protein
G4G71_RS24025	COG0247	lactate metabolic process
G4G71_RS24030	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G4G71_RS24035	COG1620	l-lactate permease
G4G71_RS24055	COG1113	amino acid transport
G4G71_RS24060	COG0625	glutathione transferase activity
G4G71_RS24070	COG2207	Transcriptional regulator
G4G71_RS24090	COG5001	Diguanylate cyclase
G4G71_RS24090	COG5002	protein histidine kinase activity
G4G71_RS24120	COG0271	Belongs to the BolA IbaG family
G4G71_RS24145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G4G71_RS24150	COG1629	transport
G4G71_RS24165	COG0697	spore germination
G4G71_RS24185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS24190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4G71_RS24195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS24200	COG0431	NADPH-dependent FMN reductase
G4G71_RS24210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4G71_RS24215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4G71_RS24220	COG0450	alkyl hydroperoxide reductase
G4G71_RS24240	COG2154	pterin-4-alpha-carbinolamine dehydratase
G4G71_RS24260	COG1840	ABC-type Fe3 transport system, periplasmic component
G4G71_RS24270	COG3842	ATPase activity
G4G71_RS24275	COG0183	Belongs to the thiolase family
G4G71_RS24290	COG2274	protein secretion by the type I secretion system
G4G71_RS24310	COG0456	acetyltransferase
G4G71_RS24315	COG0488	(ABC) transporter
G4G71_RS24345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G71_RS24355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4G71_RS24365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G4G71_RS24375	COG1196	nuclear chromosome segregation
G4G71_RS24375	COG3264	Mechanosensitive ion channel
G4G71_RS24380	COG4106	trans-aconitate 2-methyltransferase activity
G4G71_RS24405	COG0542	response to heat
G4G71_RS24415	COG1476	TRANSCRIPTIONal
G4G71_RS24420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4G71_RS24435	COG0697	spore germination
G4G71_RS24440	COG1247	-acetyltransferase
G4G71_RS24455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4G71_RS24460	COG4807	Protein conserved in bacteria
G4G71_RS24470	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4G71_RS24500	COG0583	DNA-binding transcription factor activity
G4G71_RS24530	COG3530	Putative quorum-sensing-regulated virulence factor
G4G71_RS24540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G4G71_RS24595	COG0585	pseudouridine synthase activity
G4G71_RS24600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G4G71_RS24605	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G4G71_RS24610	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G4G71_RS24620	COG2391	methyltransferase activity
G4G71_RS24625	COG0425	Belongs to the sulfur carrier protein TusA family
G4G71_RS24640	COG0148	phosphopyruvate hydratase activity
G4G71_RS24655	COG0037	tRNA processing
G4G71_RS24660	COG0825	malonyl-CoA metabolic process
G4G71_RS24670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G4G71_RS24710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G4G71_RS24735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G4G71_RS24745	COG0024	Methionine aminopeptidase
G4G71_RS24755	COG0436	Aminotransferase
G4G71_RS24760	COG0025	NhaP-type Na H and K H
G4G71_RS24765	COG1393	Belongs to the ArsC family
G4G71_RS24790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G4G71_RS24810	COG2226	methyltransferase
G4G71_RS24885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4G71_RS24890	COG1596	polysaccharide export
G4G71_RS24905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4G71_RS24930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS24935	COG1309	transcriptional regulator
G4G71_RS24940	COG0742	ribosomal rna small subunit methyltransferase
G4G71_RS24955	COG1801	Protein of unknown function DUF72
G4G71_RS24970	COG0563	adenylate kinase activity
G4G71_RS24985	COG0789	Transcriptional regulator
G4G71_RS25015	COG1073	alpha beta
G4G71_RS25045	COG4251	negative regulation of phosphorylation
G4G71_RS25045	COG5001	Diguanylate cyclase
G4G71_RS25045	COG2203	Gaf domain
G4G71_RS25045	COG3706	GGDEF domain
G4G71_RS25075	COG0840	transmembrane signaling receptor activity
G4G71_RS25080	COG1238	metal cluster binding
G4G71_RS25125	COG4574	serine-type endopeptidase inhibitor activity
G4G71_RS25140	COG0583	DNA-binding transcription factor activity
G4G71_RS25150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G4G71_RS25155	COG3842	ATPase activity
G4G71_RS25160	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS25165	COG1177	transmembrane transport
G4G71_RS25170	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS25175	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
G4G71_RS25185	COG0840	transmembrane signaling receptor activity
G4G71_RS25210	COG1902	pentaerythritol trinitrate reductase activity
G4G71_RS25215	COG1538	Outer membrane efflux protein
G4G71_RS25220	COG0577	efflux transmembrane transporter activity
G4G71_RS25220	COG1136	(ABC) transporter
G4G71_RS25225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS25255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4G71_RS25270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G4G71_RS25280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4G71_RS25290	COG3706	GGDEF domain
G4G71_RS25295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G4G71_RS25310	COG1802	Transcriptional regulator
G4G71_RS25315	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS25330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4G71_RS25345	COG0583	DNA-binding transcription factor activity
G4G71_RS25355	COG3189	MarR family transcriptional regulator
G4G71_RS25370	COG1794	racemase activity, acting on amino acids and derivatives
G4G71_RS25385	COG1320	monovalent cation:proton antiporter activity
G4G71_RS25390	COG2212	antiporter activity
G4G71_RS25400	COG0651	ATP synthesis coupled electron transport
G4G71_RS25405	COG1006	Multisubunit Na H antiporter MnhC subunit
G4G71_RS25410	COG2111	Na H antiporter
G4G71_RS25410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4G71_RS25415	COG3133	Outer membrane lipoprotein
G4G71_RS25425	COG1929	Belongs to the glycerate kinase type-1 family
G4G71_RS25450	COG1199	ATP-dependent helicase activity
G4G71_RS25485	COG2860	membrane
G4G71_RS25500	COG0653	protein targeting
G4G71_RS25520	COG0489	protein tyrosine kinase activity
G4G71_RS25540	COG0754	glutathionylspermidine amidase activity
G4G71_RS25595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4G71_RS25605	COG1611	Belongs to the LOG family
G4G71_RS25615	COG2274	protein secretion by the type I secretion system
G4G71_RS25630	COG0346	lactoylglutathione lyase activity
G4G71_RS25665	COG2223	nitrite transmembrane transporter activity
G4G71_RS25670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G4G71_RS25675	COG0243	molybdopterin cofactor binding
G4G71_RS25685	COG3842	ATPase activity
G4G71_RS25700	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4G71_RS25735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4G71_RS25745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G4G71_RS25755	COG0583	DNA-binding transcription factor activity
G4G71_RS25770	COG0583	DNA-binding transcription factor activity
G4G71_RS25780	COG0531	amino acid
G4G71_RS25795	COG1760	l-serine dehydratase
G4G71_RS25800	COG0069	glutamate synthase activity
G4G71_RS25815	COG0583	DNA-binding transcription factor activity
G4G71_RS25835	COG3011	Protein conserved in bacteria
G4G71_RS25845	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G4G71_RS25865	COG0656	L-ascorbic acid biosynthetic process
G4G71_RS25870	COG1181	Belongs to the D-alanine--D-alanine ligase family
G4G71_RS25885	COG4206	TonB-dependent receptor
G4G71_RS25900	COG0662	Cupin 2, conserved barrel domain protein
G4G71_RS25925	COG1335	isochorismatase
G4G71_RS25930	COG1704	LemA family
G4G71_RS25935	COG0501	Belongs to the peptidase M48B family
G4G71_RS25945	COG1113	amino acid transport
G4G71_RS25950	COG0500	methyltransferase
G4G71_RS25965	COG4628	conserved protein (DUF2132)
G4G71_RS25975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G4G71_RS25980	COG0583	DNA-binding transcription factor activity
G4G71_RS25990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4G71_RS26000	COG4206	TonB-dependent receptor
G4G71_RS26015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4G71_RS26050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G4G71_RS26085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4G71_RS26090	COG3086	response to oxidative stress
G4G71_RS26195	COG1024	Enoyl-CoA hydratase
G4G71_RS26210	COG2910	NAD(P)H-binding
G4G71_RS26215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS26225	COG1538	Outer membrane efflux protein
G4G71_RS26240	COG5001	Diguanylate cyclase
G4G71_RS26240	COG3300	MHYT domain
G4G71_RS26250	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G4G71_RS26290	COG3665	Urea carboxylase-associated protein
G4G71_RS26295	COG4770	biotin carboxylase activity
G4G71_RS26345	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G4G71_RS26365	COG2203	Gaf domain
G4G71_RS26365	COG5001	Diguanylate cyclase
G4G71_RS26365	COG4251	negative regulation of phosphorylation
G4G71_RS26365	COG3706	GGDEF domain
G4G71_RS26390	COG0745	RESPONSE REGULATOR receiver
G4G71_RS26405	COG2259	Doxx family
G4G71_RS26415	COG1725	Transcriptional regulator
G4G71_RS26420	COG1764	response to oxidative stress
G4G71_RS26430	COG3220	belongs to the UPF0276 family
G4G71_RS26460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G4G71_RS26465	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS26475	COG4941	Belongs to the sigma-70 factor family
G4G71_RS26500	COG3795	YCII-related domain
G4G71_RS26510	COG3121	Chaperone
G4G71_RS26525	COG3121	Chaperone
G4G71_RS26530	COG2197	response regulator
G4G71_RS26560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4G71_RS26565	COG1074	ATP-dependent DNA helicase activity
G4G71_RS26570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G4G71_RS26580	COG0583	DNA-binding transcription factor activity
G4G71_RS26605	COG1230	cation diffusion facilitator family transporter
G4G71_RS26610	COG0564	pseudouridine synthase activity
G4G71_RS26620	COG3829	transcription factor binding
G4G71_RS26630	COG0306	phosphate transporter
G4G71_RS26690	COG4964	Belongs to the GSP D family
G4G71_RS26715	COG0433	COG0433 Predicted ATPase
G4G71_RS26730	COG3642	lipopolysaccharide core region biosynthetic process
G4G71_RS26740	COG0642	Histidine kinase
G4G71_RS26745	COG0745	RESPONSE REGULATOR receiver
G4G71_RS26775	COG0748	coenzyme F420 binding
G4G71_RS26780	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS26790	COG3695	enzyme binding
G4G71_RS26795	COG2211	Major facilitator Superfamily
G4G71_RS26800	COG0668	transmembrane transport
G4G71_RS26810	COG0745	RESPONSE REGULATOR receiver
G4G71_RS26825	COG2096	Adenosyltransferase
G4G71_RS26830	COG0494	nUDIX hydrolase
G4G71_RS26890	COG0772	Belongs to the SEDS family
G4G71_RS26905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4G71_RS26945	COG3107	peptidoglycan biosynthetic process
G4G71_RS26950	COG0792	nuclease activity
G4G71_RS26960	COG2823	Periplasmic or secreted lipoprotein
G4G71_RS26965	COG2969	positive regulation of protein catabolic process
G4G71_RS26970	COG0625	glutathione transferase activity
G4G71_RS26975	COG2857	Cytochrome c1
G4G71_RS26980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4G71_RS26985	COG0723	plastoquinol--plastocyanin reductase activity
G4G71_RS27000	COG0667	Aldo Keto reductase
G4G71_RS27005	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS27020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G4G71_RS27030	COG2945	thiolester hydrolase activity
G4G71_RS27045	COG0175	sulfate reduction
G4G71_RS27050	COG2951	lytic endotransglycosylase activity
G4G71_RS27060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4G71_RS27065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G4G71_RS27100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G4G71_RS27105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G4G71_RS27110	COG1127	ABC transporter
G4G71_RS27120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G4G71_RS27130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G4G71_RS27135	COG1137	ATPase activity
G4G71_RS27190	COG0312	modulator of DNA gyrase
G4G71_RS27200	COG0312	modulator of DNA gyrase
G4G71_RS27205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4G71_RS27215	COG1530	ribonuclease E activity
G4G71_RS27230	COG1792	Involved in formation and maintenance of cell shape
G4G71_RS27235	COG1077	Cell shape determining protein MreB Mrl
G4G71_RS27250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4G71_RS27255	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G4G71_RS27260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4G71_RS27265	COG4676	Protein conserved in bacteria
G4G71_RS27270	COG5445	Predicted secreted protein (DUF2300)
G4G71_RS27285	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
G4G71_RS27290	COG4676	Protein conserved in bacteria
G4G71_RS27310	COG0739	heme binding
G4G71_RS27315	COG4178	(ABC) transporter
G4G71_RS27320	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G4G71_RS27335	COG0747	negative chemotaxis
G4G71_RS27340	COG0747	negative chemotaxis
G4G71_RS27345	COG0601	transmembrane transport
G4G71_RS27350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4G71_RS27355	COG0444	Belongs to the ABC transporter superfamily
G4G71_RS27360	COG4608	Belongs to the ABC transporter superfamily
G4G71_RS27370	COG1280	lysine exporter protein (LysE YggA)
G4G71_RS27380	COG1984	allophanate hydrolase subunit 2
G4G71_RS27385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G4G71_RS27405	COG4774	siderophore transport
G4G71_RS27420	COG2194	sulfuric ester hydrolase activity
G4G71_RS27425	COG0019	diaminopimelate decarboxylase activity
G4G71_RS27475	COG1309	transcriptional regulator
G4G71_RS27500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4G71_RS27515	COG0726	polysaccharide deacetylase
G4G71_RS27525	COG2076	Multidrug Resistance protein
G4G71_RS27540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4G71_RS27540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4G71_RS27540	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G4G71_RS27545	COG1105	Belongs to the carbohydrate kinase PfkB family
G4G71_RS27555	COG1609	Transcriptional regulator
G4G71_RS27560	COG0084	hydrolase, TatD family'
G4G71_RS27590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4G71_RS27605	COG4969	Belongs to the N-Me-Phe pilin family
G4G71_RS27660	COG1252	NADH dehydrogenase
G4G71_RS27695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4G71_RS27700	COG2274	protein secretion by the type I secretion system
G4G71_RS27705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G4G71_RS27705	COG2885	chlorophyll binding
G4G71_RS27775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS27815	COG4969	Belongs to the N-Me-Phe pilin family
G4G71_RS27825	COG1047	Peptidyl-prolyl cis-trans
G4G71_RS27840	COG0196	riboflavin kinase activity
G4G71_RS27845	COG0728	peptidoglycan biosynthetic process
G4G71_RS27855	COG3045	CreA protein
G4G71_RS27870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G4G71_RS27880	COG0142	geranyltranstransferase activity
G4G71_RS27885	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G4G71_RS27890	COG0545	Peptidyl-prolyl cis-trans isomerase
G4G71_RS27910	COG1067	ATP-dependent peptidase activity
G4G71_RS27930	COG4650	regulator
G4G71_RS27945	COG1690	Belongs to the RtcB family
G4G71_RS27950	COG0430	RNA-3'-phosphate cyclase activity
G4G71_RS27975	COG0488	(ABC) transporter
G4G71_RS27990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4G71_RS27995	COG2252	PERMEase
G4G71_RS28025	COG0436	Aminotransferase
G4G71_RS28035	COG0644	oxidoreductase
G4G71_RS28040	COG0475	glutathione-regulated potassium exporter activity
G4G71_RS28045	COG2321	neutral zinc metallopeptidase
G4G71_RS28065	COG2814	Major facilitator Superfamily
G4G71_RS28085	COG2608	mercury ion transmembrane transporter activity
G4G71_RS28095	COG2217	Heavy metal translocating P-type atpase
G4G71_RS28115	COG0697	spore germination
G4G71_RS28135	COG2205	protein histidine kinase activity
G4G71_RS28135	COG0784	Response regulator, receiver
G4G71_RS28135	COG5002	protein histidine kinase activity
G4G71_RS28160	COG0765	amino acid transport
G4G71_RS28165	COG0765	amino acid transport
G4G71_RS28170	COG1126	abc transporter atp-binding protein
G4G71_RS28220	COG2226	methyltransferase
G4G71_RS28230	COG1802	Transcriptional regulator
G4G71_RS28260	COG1346	cytolysis
G4G71_RS28280	COG0702	epimerase
G4G71_RS28295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G4G71_RS28300	COG3284	Transcriptional regulator
G4G71_RS28305	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS28320	COG4303	Ethanolamine ammonia lyase large subunit
G4G71_RS28325	COG4302	ethanolamine ammonia-lyase activity
G4G71_RS28355	COG4968	Prepilin-type N-terminal cleavage methylation domain
G4G71_RS28360	COG0456	acetyltransferase
G4G71_RS28370	COG0586	Pfam SNARE associated Golgi protein
G4G71_RS28395	COG0142	geranyltranstransferase activity
G4G71_RS28400	COG2186	Transcriptional regulator
G4G71_RS28410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4G71_RS28440	COG0765	amino acid transport
G4G71_RS28445	COG0765	amino acid transport
G4G71_RS28450	COG1126	abc transporter atp-binding protein
G4G71_RS28460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4G71_RS28465	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS28475	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G4G71_RS28480	COG4206	TonB-dependent receptor
G4G71_RS28490	COG1946	Acyl-CoA thioesterase
G4G71_RS28505	COG2814	Major facilitator Superfamily
G4G71_RS28510	COG0123	including yeast histone deacetylase and acetoin utilization protein
G4G71_RS28520	COG2081	HI0933 family
G4G71_RS28535	COG1012	belongs to the aldehyde dehydrogenase family
G4G71_RS28540	COG1177	transmembrane transport
G4G71_RS28545	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS28555	COG3842	ATPase activity
G4G71_RS28565	COG0513	Belongs to the DEAD box helicase family
G4G71_RS28575	COG3416	Protein conserved in bacteria
G4G71_RS28605	COG1643	Atp-dependent helicase
G4G71_RS28615	COG2318	DinB family
G4G71_RS28630	COG1522	sequence-specific DNA binding
G4G71_RS28650	COG0653	protein targeting
G4G71_RS28655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G4G71_RS28660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G4G71_RS28675	COG1598	PFAM Uncharacterised protein family UPF0150
G4G71_RS28685	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS28705	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS28710	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS28715	COG1024	Enoyl-CoA hydratase
G4G71_RS28720	COG1960	acyl-CoA dehydrogenase activity
G4G71_RS28730	COG2814	Major facilitator Superfamily
G4G71_RS28735	COG2030	dehydratase
G4G71_RS28760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4G71_RS28765	COG0784	Response regulator, receiver
G4G71_RS28765	COG5002	protein histidine kinase activity
G4G71_RS28770	COG0351	phosphomethylpyrimidine kinase
G4G71_RS28805	COG1702	phosphate starvation-inducible protein PhoH
G4G71_RS28815	COG4535	Mg2 and Co2 transporter CorC
G4G71_RS28850	COG2814	Major facilitator Superfamily
G4G71_RS28855	COG3795	YCII-related domain
G4G71_RS28870	COG2951	lytic endotransglycosylase activity
G4G71_RS28890	COG1686	Belongs to the peptidase S11 family
G4G71_RS28900	COG2951	lytic endotransglycosylase activity
G4G71_RS28905	COG0772	Belongs to the SEDS family
G4G71_RS28910	COG0768	penicillin binding
G4G71_RS28950	COG0586	Pfam SNARE associated Golgi protein
G4G71_RS28955	COG0583	DNA-binding transcription factor activity
G4G71_RS28980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4G71_RS28985	COG3577	Aspartyl protease
G4G71_RS28995	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G4G71_RS29000	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G4G71_RS29025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4G71_RS29025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4G71_RS29040	COG2264	protein methyltransferase activity
G4G71_RS29045	COG3118	belongs to the thioredoxin family
G4G71_RS29080	COG3094	Invasion gene expression up-regulator, SirB
G4G71_RS29085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4G71_RS29100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4G71_RS29105	COG0348	domain, Protein
G4G71_RS29110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4G71_RS29115	COG2205	protein histidine kinase activity
G4G71_RS29150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G4G71_RS29165	COG0625	glutathione transferase activity
G4G71_RS29205	COG1595	DNA-templated transcription, initiation
G4G71_RS29210	COG3712	iron ion homeostasis
G4G71_RS29240	COG2814	Major facilitator Superfamily
G4G71_RS29285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G4G71_RS29295	COG0200	Binds to the 23S rRNA
G4G71_RS29360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G4G71_RS29365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G4G71_RS29395	COG0051	transcription antitermination factor activity, RNA binding
G4G71_RS29405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G4G71_RS29495	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G4G71_RS29495	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G4G71_RS29525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G4G71_RS29530	COG0739	heme binding
G4G71_RS29540	COG0316	Belongs to the HesB IscA family
G4G71_RS29545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G4G71_RS29555	COG2070	2-Nitropropane dioxygenase
G4G71_RS29565	COG1028	Short-chain dehydrogenase reductase Sdr
G4G71_RS29570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4G71_RS29575	COG0537	adenosine 5'-monophosphoramidase activity
G4G71_RS29590	COG1765	OsmC-like protein
G4G71_RS29625	COG3179	chitinase
G4G71_RS29745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G4G71_RS29755	COG1176	ABC-type spermidine putrescine transport system, permease component I
G4G71_RS29765	COG3842	ATPase activity
G4G71_RS29775	COG2197	response regulator
G4G71_RS29815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G4G71_RS29825	COG2967	ApaG domain
G4G71_RS29840	COG2766	serine protein kinase
G4G71_RS29850	COG2719	SpoVR family
G4G71_RS29870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin