locus-tag	class	description
PotMrB4_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PotMrB4_RS00050	COG2818	Glycosylase
PotMrB4_RS00075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PotMrB4_RS00080	COG0569	domain protein
PotMrB4_RS00085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PotMrB4_RS00090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PotMrB4_RS00095	COG0242	peptide deformylase activity
PotMrB4_RS00100	COG1652	LysM domain
PotMrB4_RS00105	COG0758	DNA mediated transformation
PotMrB4_RS00110	COG0009	L-threonylcarbamoyladenylate synthase
PotMrB4_RS00125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PotMrB4_RS00140	COG3119	arylsulfatase activity
PotMrB4_RS00145	COG0583	DNA-binding transcription factor activity
PotMrB4_RS00155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PotMrB4_RS00190	COG0159	tryptophan synthase activity
PotMrB4_RS00220	COG3360	Dodecin
PotMrB4_RS00230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PotMrB4_RS00260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PotMrB4_RS00315	COG0659	secondary active sulfate transmembrane transporter activity
PotMrB4_RS00325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PotMrB4_RS00330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PotMrB4_RS00335	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PotMrB4_RS00365	COG0109	protoheme IX farnesyltransferase activity
PotMrB4_RS00385	COG1629	transport
PotMrB4_RS00415	COG2832	Protein of unknown function (DUF454)
PotMrB4_RS00425	COG2011	ABC-type metal ion transport system permease component
PotMrB4_RS00430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PotMrB4_RS00445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PotMrB4_RS00455	COG0735	belongs to the Fur family
PotMrB4_RS00460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PotMrB4_RS00525	COG0415	Belongs to the DNA photolyase family
PotMrB4_RS00535	COG2095	MarC family integral membrane protein
PotMrB4_RS00540	COG3023	N-Acetylmuramoyl-L-alanine amidase
PotMrB4_RS00545	COG5002	protein histidine kinase activity
PotMrB4_RS00550	COG2204	response regulator
PotMrB4_RS00580	COG0700	Nucleoside recognition
PotMrB4_RS00590	COG0612	Peptidase, M16
PotMrB4_RS00595	COG0840	transmembrane signaling receptor activity
PotMrB4_RS00610	COG0385	Bile acid
PotMrB4_RS00615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PotMrB4_RS00625	COG1283	sodium-dependent phosphate transmembrane transporter activity
PotMrB4_RS00630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PotMrB4_RS00635	COG1074	ATP-dependent DNA helicase activity
PotMrB4_RS00640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PotMrB4_RS00645	COG1253	flavin adenine dinucleotide binding
PotMrB4_RS00660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PotMrB4_RS00705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PotMrB4_RS00710	COG0583	DNA-binding transcription factor activity
PotMrB4_RS00720	COG0848	biopolymer transport protein
PotMrB4_RS00755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PotMrB4_RS00760	COG1758	RNA polymerase activity
PotMrB4_RS00770	COG1561	YicC-like family, N-terminal region
PotMrB4_RS00775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PotMrB4_RS00785	COG0708	Exodeoxyribonuclease III
PotMrB4_RS00815	COG0756	dUTP diphosphatase activity
PotMrB4_RS00820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PotMrB4_RS00825	COG2003	Belongs to the UPF0758 family
PotMrB4_RS00835	COG0747	negative chemotaxis
PotMrB4_RS00840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PotMrB4_RS00845	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PotMrB4_RS00855	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS00860	COG2814	Major facilitator Superfamily
PotMrB4_RS00865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS00875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS00880	COG0251	oxidation-reduction process
PotMrB4_RS00885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PotMrB4_RS00900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PotMrB4_RS00920	COG0583	DNA-binding transcription factor activity
PotMrB4_RS00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PotMrB4_RS00935	COG0606	chelatase, subunit chli
PotMrB4_RS00945	COG0347	Belongs to the P(II) protein family
PotMrB4_RS00950	COG0004	ammonium transporteR
PotMrB4_RS00955	COG0432	Pfam Uncharacterised protein family UPF0047
PotMrB4_RS00965	COG0546	phosphoglycolate phosphatase activity
PotMrB4_RS00980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PotMrB4_RS01000	COG1965	Belongs to the frataxin family
PotMrB4_RS01010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PotMrB4_RS01035	COG0625	glutathione transferase activity
PotMrB4_RS01045	COG3275	phosphorelay sensor kinase activity
PotMrB4_RS01055	COG0181	hydroxymethylbilane synthase activity
PotMrB4_RS01105	COG0488	(ABC) transporter
PotMrB4_RS01145	COG1671	Belongs to the UPF0178 family
PotMrB4_RS01150	COG2050	protein possibly involved in aromatic compounds catabolism
PotMrB4_RS01155	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PotMrB4_RS01170	COG0586	Pfam SNARE associated Golgi protein
PotMrB4_RS01185	COG0248	Ppx GppA phosphatase
PotMrB4_RS01200	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PotMrB4_RS01210	COG0583	DNA-binding transcription factor activity
PotMrB4_RS01220	COG1176	ABC-type spermidine putrescine transport system, permease component I
PotMrB4_RS01225	COG1177	transmembrane transport
PotMrB4_RS01260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PotMrB4_RS01280	COG3079	Belongs to the UPF0149 family
PotMrB4_RS01285	COG0006	proline dipeptidase activity
PotMrB4_RS01290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PotMrB4_RS01300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PotMrB4_RS01310	COG1178	ABC-type Fe3 transport system permease component
PotMrB4_RS01360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS01385	COG0523	cobalamin synthesis protein
PotMrB4_RS01395	COG0174	glutamine synthetase
PotMrB4_RS01400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PotMrB4_RS01405	COG0174	glutamine synthetase
PotMrB4_RS01430	COG3842	ATPase activity
PotMrB4_RS01435	COG1176	ABC-type spermidine putrescine transport system, permease component I
PotMrB4_RS01440	COG1177	transmembrane transport
PotMrB4_RS01485	COG1683	Conserved Protein
PotMrB4_RS01500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PotMrB4_RS01505	COG0277	FAD linked oxidase domain protein
PotMrB4_RS01510	COG0179	Fumarylacetoacetate (FAA) hydrolase
PotMrB4_RS01515	COG3204	pilus organization
PotMrB4_RS01520	COG3111	PFAM Bacterial OB fold (BOF) protein
PotMrB4_RS01550	COG0531	amino acid
PotMrB4_RS01560	COG1177	transmembrane transport
PotMrB4_RS01565	COG1176	ABC-type spermidine putrescine transport system, permease component I
PotMrB4_RS01570	COG3842	ATPase activity
PotMrB4_RS01580	COG3204	pilus organization
PotMrB4_RS01590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PotMrB4_RS01595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PotMrB4_RS01605	COG0702	epimerase
PotMrB4_RS01620	COG0494	nUDIX hydrolase
PotMrB4_RS01625	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
PotMrB4_RS01630	COG3706	GGDEF domain
PotMrB4_RS01640	COG0730	response to heat
PotMrB4_RS01645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PotMrB4_RS01650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PotMrB4_RS01655	COG3719	Belongs to the RNase T2 family
PotMrB4_RS01660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PotMrB4_RS01670	COG0584	glycerophosphoryl diester phosphodiesterase
PotMrB4_RS01685	COG2233	PERMEase
PotMrB4_RS01695	COG0129	dihydroxy-acid dehydratase activity
PotMrB4_RS01710	COG0693	protein deglycase activity
PotMrB4_RS01725	COG0204	Acyl-transferase
PotMrB4_RS01745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PotMrB4_RS01755	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PotMrB4_RS01775	COG0429	hydrolase of the alpha beta-hydrolase fold
PotMrB4_RS01780	COG0742	ribosomal rna small subunit methyltransferase
PotMrB4_RS01785	COG0612	Peptidase, M16
PotMrB4_RS01790	COG0612	Peptidase, M16
PotMrB4_RS01795	COG0552	protein localization to endoplasmic reticulum
PotMrB4_RS01800	COG2884	Cell division ATP-binding protein ftsE
PotMrB4_RS01805	COG2177	Part of the ABC transporter FtsEX involved in
PotMrB4_RS01820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PotMrB4_RS01825	COG2363	Small membrane protein
PotMrB4_RS01835	COG2022	thiamine diphosphate biosynthetic process
PotMrB4_RS01840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PotMrB4_RS01860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PotMrB4_RS01865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PotMrB4_RS01875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PotMrB4_RS01875	COG2813	Specifically methylates the guanine in position
PotMrB4_RS01880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PotMrB4_RS01890	COG1872	DUF167
PotMrB4_RS01945	COG0540	Belongs to the ATCase OTCase family
PotMrB4_RS01950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PotMrB4_RS02000	COG0643	Histidine kinase
PotMrB4_RS02000	COG0784	Response regulator, receiver
PotMrB4_RS02000	COG2198	Histidine kinase
PotMrB4_RS02005	COG2201	protein-glutamate methylesterase activity
PotMrB4_RS02015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PotMrB4_RS02030	COG3038	cytochrome b561
PotMrB4_RS02035	COG2353	YceI-like domain
PotMrB4_RS02040	COG0513	Belongs to the DEAD box helicase family
PotMrB4_RS02055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PotMrB4_RS02060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PotMrB4_RS02080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PotMrB4_RS02090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PotMrB4_RS02115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PotMrB4_RS02120	COG0126	phosphoglycerate kinase activity
PotMrB4_RS02150	COG1451	nucleotide metabolic process
PotMrB4_RS02175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS02185	COG1289	transmembrane transporter activity
PotMrB4_RS02200	COG0513	Belongs to the DEAD box helicase family
PotMrB4_RS02205	COG0477	Major facilitator Superfamily
PotMrB4_RS02225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PotMrB4_RS02250	COG4175	Glycine betaine
PotMrB4_RS02260	COG1760	l-serine dehydratase
PotMrB4_RS02280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PotMrB4_RS02285	COG0247	lactate metabolic process
PotMrB4_RS02285	COG2181	nitrate reductase activity
PotMrB4_RS02290	COG0446	pyridine nucleotide-disulphide oxidoreductase
PotMrB4_RS02290	COG1902	pentaerythritol trinitrate reductase activity
PotMrB4_RS02315	COG3383	formate dehydrogenase (NAD+) activity
PotMrB4_RS02335	COG3246	L-lysine catabolic process to acetate
PotMrB4_RS02355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS02355	COG2205	protein histidine kinase activity
PotMrB4_RS02365	COG2197	response regulator
PotMrB4_RS02370	COG3539	Fimbrial protein
PotMrB4_RS02375	COG3121	Chaperone
PotMrB4_RS02380	COG3188	usher protein
PotMrB4_RS02395	COG1017	nitric oxide dioxygenase activity
PotMrB4_RS02395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PotMrB4_RS02445	COG1063	alcohol dehydrogenase
PotMrB4_RS02450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PotMrB4_RS02455	COG0204	Acyl-transferase
PotMrB4_RS02470	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS02475	COG2205	protein histidine kinase activity
PotMrB4_RS02485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PotMrB4_RS02485	COG0517	IMP dehydrogenase activity
PotMrB4_RS02490	COG4452	Inner membrane protein CreD
PotMrB4_RS02525	COG4774	siderophore transport
PotMrB4_RS02530	COG3712	iron ion homeostasis
PotMrB4_RS02535	COG1595	DNA-templated transcription, initiation
PotMrB4_RS02545	COG0517	IMP dehydrogenase activity
PotMrB4_RS02545	COG0516	GMP reductase activity
PotMrB4_RS02550	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS02555	COG1953	Uracil, thiamine, allantoin
PotMrB4_RS02590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PotMrB4_RS02595	COG2005	Transcriptional regulator
PotMrB4_RS02595	COG3585	molybdate ion transport
PotMrB4_RS02620	COG0511	ligase activity, forming carbon-carbon bonds
PotMrB4_RS02625	COG0439	Biotin carboxylase
PotMrB4_RS02635	COG1984	allophanate hydrolase subunit 2
PotMrB4_RS02650	COG2226	methyltransferase
PotMrB4_RS02650	COG1073	alpha beta
PotMrB4_RS02675	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS02685	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS02690	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS02695	COG0515	serine threonine protein kinase
PotMrB4_RS02735	COG2204	response regulator
PotMrB4_RS02790	COG0583	DNA-binding transcription factor activity
PotMrB4_RS02795	COG2258	MOSC domain
PotMrB4_RS02805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PotMrB4_RS02815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PotMrB4_RS02830	COG1522	sequence-specific DNA binding
PotMrB4_RS02850	COG3539	Fimbrial protein
PotMrB4_RS02865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS02875	COG0174	glutamine synthetase
PotMrB4_RS02895	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PotMrB4_RS02900	COG0010	Belongs to the arginase family
PotMrB4_RS02905	COG4670	ketone body catabolic process
PotMrB4_RS02910	COG2610	gluconate transmembrane transporter activity
PotMrB4_RS02930	COG0210	DNA helicase
PotMrB4_RS02960	COG0358	DNA primase activity
PotMrB4_RS02970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PotMrB4_RS02990	COG2885	chlorophyll binding
PotMrB4_RS02990	COG3047	cAMP biosynthetic process
PotMrB4_RS02995	COG2199	diguanylate cyclase activity
PotMrB4_RS03005	COG0617	tRNA 3'-terminal CCA addition
PotMrB4_RS03015	COG2719	SpoVR family
PotMrB4_RS03020	COG2718	Belongs to the UPF0229 family
PotMrB4_RS03025	COG2766	serine protein kinase
PotMrB4_RS03030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PotMrB4_RS03035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PotMrB4_RS03040	COG2967	ApaG domain
PotMrB4_RS03045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PotMrB4_RS03055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PotMrB4_RS03060	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PotMrB4_RS03070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PotMrB4_RS03075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PotMrB4_RS03090	COG2197	response regulator
PotMrB4_RS03095	COG3842	ATPase activity
PotMrB4_RS03105	COG1176	ABC-type spermidine putrescine transport system, permease component I
PotMrB4_RS03120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PotMrB4_RS03130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PotMrB4_RS03135	COG0512	Glutamine amidotransferase of anthranilate synthase
PotMrB4_RS03155	COG1765	OsmC-like protein
PotMrB4_RS03165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PotMrB4_RS03170	COG0537	adenosine 5'-monophosphoramidase activity
PotMrB4_RS03180	COG4221	oxidoreductase activity
PotMrB4_RS03215	COG0316	Belongs to the HesB IscA family
PotMrB4_RS03220	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PotMrB4_RS03225	COG0739	heme binding
PotMrB4_RS03230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PotMrB4_RS03260	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PotMrB4_RS03260	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PotMrB4_RS03315	COG0081	regulation of translation
PotMrB4_RS03330	COG0085	RNA polymerase activity
PotMrB4_RS03335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PotMrB4_RS03340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PotMrB4_RS03345	COG0049	tRNA binding
PotMrB4_RS03350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PotMrB4_RS03360	COG0051	transcription antitermination factor activity, RNA binding
PotMrB4_RS03365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PotMrB4_RS03375	COG0089	rRNA binding
PotMrB4_RS03380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PotMrB4_RS03390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PotMrB4_RS03395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PotMrB4_RS03405	COG0255	Belongs to the universal ribosomal protein uL29 family
PotMrB4_RS03410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PotMrB4_RS03415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PotMrB4_RS03420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PotMrB4_RS03425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PotMrB4_RS03430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PotMrB4_RS03435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PotMrB4_RS03450	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PotMrB4_RS03460	COG0200	Binds to the 23S rRNA
PotMrB4_RS03475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PotMrB4_RS03485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PotMrB4_RS03490	COG0202	RNA polymerase activity
PotMrB4_RS03495	COG0203	ribosomal protein L17
PotMrB4_RS03500	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PotMrB4_RS03510	COG2814	Major facilitator Superfamily
PotMrB4_RS03660	COG3712	iron ion homeostasis
PotMrB4_RS03665	COG1595	DNA-templated transcription, initiation
PotMrB4_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS03685	COG2207	Transcriptional regulator
PotMrB4_RS03690	COG2205	protein histidine kinase activity
PotMrB4_RS03690	COG3437	response regulator, receiver
PotMrB4_RS03690	COG4999	Histidine kinase
PotMrB4_RS03690	COG3850	Histidine kinase
PotMrB4_RS03700	COG0804	urea catabolic process
PotMrB4_RS03705	COG0832	Belongs to the urease beta subunit family
PotMrB4_RS03720	COG0831	urea catabolic process
PotMrB4_RS03725	COG0829	nickel cation binding
PotMrB4_RS03735	COG0411	ABC transporter
PotMrB4_RS03750	COG0683	leucine binding
PotMrB4_RS03755	COG2095	MarC family integral membrane protein
PotMrB4_RS03790	COG2264	protein methyltransferase activity
PotMrB4_RS03810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PotMrB4_RS03840	COG0023	Translation Initiation Factor
PotMrB4_RS03845	COG1166	arginine decarboxylase activity
PotMrB4_RS03860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PotMrB4_RS03865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PotMrB4_RS03875	COG0534	Mate efflux family protein
PotMrB4_RS03880	COG2373	Large extracellular alpha-helical protein
PotMrB4_RS03885	COG4953	penicillin-binding protein 1C
PotMrB4_RS03890	COG0840	transmembrane signaling receptor activity
PotMrB4_RS03915	COG1902	pentaerythritol trinitrate reductase activity
PotMrB4_RS03915	COG0446	pyridine nucleotide-disulphide oxidoreductase
PotMrB4_RS03925	COG0437	4 iron, 4 sulfur cluster binding
PotMrB4_RS03930	COG2864	formate dehydrogenase
PotMrB4_RS03945	COG3276	selenocysteine insertion sequence binding
PotMrB4_RS03955	COG2026	Addiction module toxin, RelE StbE family
PotMrB4_RS04025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PotMrB4_RS04085	COG2223	nitrite transmembrane transporter activity
PotMrB4_RS04100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PotMrB4_RS04105	COG2824	Alkylphosphonate utilization operon protein PhnA
PotMrB4_RS04125	COG1295	ribonuclease BN
PotMrB4_RS04155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PotMrB4_RS04160	COG3047	cAMP biosynthetic process
PotMrB4_RS04175	COG0577	efflux transmembrane transporter activity
PotMrB4_RS04175	COG1136	(ABC) transporter
PotMrB4_RS04190	COG3118	belongs to the thioredoxin family
PotMrB4_RS04195	COG2264	protein methyltransferase activity
PotMrB4_RS04210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PotMrB4_RS04210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PotMrB4_RS04225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PotMrB4_RS04240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PotMrB4_RS04250	COG3577	Aspartyl protease
PotMrB4_RS04255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PotMrB4_RS04265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PotMrB4_RS04270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PotMrB4_RS04275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PotMrB4_RS04280	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS04320	COG3842	ATPase activity
PotMrB4_RS04330	COG0142	geranyltranstransferase activity
PotMrB4_RS04335	COG1722	exodeoxyribonuclease VII activity
PotMrB4_RS04340	COG0730	response to heat
PotMrB4_RS04375	COG3220	belongs to the UPF0276 family
PotMrB4_RS04385	COG1595	DNA-templated transcription, initiation
PotMrB4_RS04390	COG4944	Protein of unknown function (DUF1109)
PotMrB4_RS04395	COG1944	ATP diphosphatase activity
PotMrB4_RS04405	COG2081	HI0933 family
PotMrB4_RS04425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PotMrB4_RS04435	COG3228	Belongs to the MtfA family
PotMrB4_RS04440	COG0586	Pfam SNARE associated Golgi protein
PotMrB4_RS04450	COG0456	acetyltransferase
PotMrB4_RS04455	COG0427	acetyl-CoA hydrolase
PotMrB4_RS04480	COG0210	DNA helicase
PotMrB4_RS04490	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS04510	COG4303	Ethanolamine ammonia lyase large subunit
PotMrB4_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS04530	COG3284	Transcriptional regulator
PotMrB4_RS04545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PotMrB4_RS04560	COG0438	transferase activity, transferring glycosyl groups
PotMrB4_RS04570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PotMrB4_RS04585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PotMrB4_RS04590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PotMrB4_RS04595	COG2226	methyltransferase
PotMrB4_RS04600	COG0702	epimerase
PotMrB4_RS04625	COG1346	cytolysis
PotMrB4_RS04635	COG0586	Pfam SNARE associated Golgi protein
PotMrB4_RS04660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PotMrB4_RS04675	COG0768	penicillin binding
PotMrB4_RS04680	COG0772	Belongs to the SEDS family
PotMrB4_RS04685	COG2951	lytic endotransglycosylase activity
PotMrB4_RS04695	COG1686	Belongs to the peptidase S11 family
PotMrB4_RS04700	COG2921	Belongs to the UPF0250 family
PotMrB4_RS04705	COG0321	lipoyl(octanoyl) transferase activity
PotMrB4_RS04710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PotMrB4_RS04715	COG2951	lytic endotransglycosylase activity
PotMrB4_RS04735	COG0495	leucyl-tRNA aminoacylation
PotMrB4_RS04745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PotMrB4_RS04750	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PotMrB4_RS04755	COG4535	Mg2 and Co2 transporter CorC
PotMrB4_RS04760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PotMrB4_RS04765	COG1702	phosphate starvation-inducible protein PhoH
PotMrB4_RS04785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PotMrB4_RS04795	COG0351	phosphomethylpyrimidine kinase
PotMrB4_RS04810	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS04830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PotMrB4_RS04860	COG1522	sequence-specific DNA binding
PotMrB4_RS04870	COG2318	DinB family
PotMrB4_RS04880	COG1643	Atp-dependent helicase
PotMrB4_RS04915	COG1522	sequence-specific DNA binding
PotMrB4_RS04920	COG0697	spore germination
PotMrB4_RS04925	COG0513	Belongs to the DEAD box helicase family
PotMrB4_RS04965	COG3179	chitinase
PotMrB4_RS04970	COG3501	Rhs element vgr protein
PotMrB4_RS04980	COG0123	including yeast histone deacetylase and acetoin utilization protein
PotMrB4_RS04990	COG1946	Acyl-CoA thioesterase
PotMrB4_RS05000	COG2321	neutral zinc metallopeptidase
PotMrB4_RS05030	COG4319	ketosteroid isomerase
PotMrB4_RS05035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PotMrB4_RS05045	COG0653	protein targeting
PotMrB4_RS05050	COG2252	PERMEase
PotMrB4_RS05070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PotMrB4_RS05070	COG2010	Cytochrome c
PotMrB4_RS05085	COG1271	oxidase subunit
PotMrB4_RS05090	COG1294	oxidase, subunit
PotMrB4_RS05125	COG3278	Belongs to the heme-copper respiratory oxidase family
PotMrB4_RS05135	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PotMrB4_RS05145	COG1253	flavin adenine dinucleotide binding
PotMrB4_RS05150	COG1970	mechanosensitive ion channel activity
PotMrB4_RS05195	COG1966	Carbon starvation protein
PotMrB4_RS05200	COG2879	small protein
PotMrB4_RS05205	COG0523	cobalamin synthesis protein
PotMrB4_RS05210	COG1595	DNA-templated transcription, initiation
PotMrB4_RS05220	COG4774	siderophore transport
PotMrB4_RS05255	COG3121	Chaperone
PotMrB4_RS05265	COG0488	(ABC) transporter
PotMrB4_RS05285	COG0430	RNA-3'-phosphate cyclase activity
PotMrB4_RS05300	COG3541	Predicted nucleotidyltransferase
PotMrB4_RS05310	COG1690	Belongs to the RtcB family
PotMrB4_RS05320	COG4650	regulator
PotMrB4_RS05325	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
PotMrB4_RS05340	COG1067	ATP-dependent peptidase activity
PotMrB4_RS05350	COG2862	Uncharacterized protein family, UPF0114
PotMrB4_RS05355	COG0545	Peptidyl-prolyl cis-trans isomerase
PotMrB4_RS05365	COG0142	geranyltranstransferase activity
PotMrB4_RS05370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PotMrB4_RS05385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PotMrB4_RS05390	COG3045	CreA protein
PotMrB4_RS05395	COG0268	Binds directly to 16S ribosomal RNA
PotMrB4_RS05400	COG0728	peptidoglycan biosynthetic process
PotMrB4_RS05405	COG0196	riboflavin kinase activity
PotMrB4_RS05410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PotMrB4_RS05420	COG1047	Peptidyl-prolyl cis-trans
PotMrB4_RS05425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PotMrB4_RS05535	COG1830	Aldolase
PotMrB4_RS05545	COG2890	protein-(glutamine-N5) methyltransferase activity
PotMrB4_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS05575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PotMrB4_RS05575	COG2755	lipolytic protein G-D-S-L family
PotMrB4_RS05590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PotMrB4_RS05590	COG2169	Transcriptional regulator
PotMrB4_RS05610	COG3145	DNA-N1-methyladenine dioxygenase activity
PotMrB4_RS05620	COG0583	DNA-binding transcription factor activity
PotMrB4_RS05625	COG1252	NADH dehydrogenase
PotMrB4_RS05665	COG0237	dephospho-CoA kinase activity
PotMrB4_RS05670	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PotMrB4_RS05685	COG4969	Belongs to the N-Me-Phe pilin family
PotMrB4_RS05690	COG3307	-O-antigen
PotMrB4_RS05725	COG0084	hydrolase, TatD family'
PotMrB4_RS05745	COG4774	siderophore transport
PotMrB4_RS05750	COG3128	pkhd-type hydroxylase
PotMrB4_RS05760	COG4774	siderophore transport
PotMrB4_RS05765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PotMrB4_RS05775	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PotMrB4_RS05780	COG1984	allophanate hydrolase subunit 2
PotMrB4_RS05785	COG4608	Belongs to the ABC transporter superfamily
PotMrB4_RS05790	COG0444	Belongs to the ABC transporter superfamily
PotMrB4_RS05795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PotMrB4_RS05800	COG0601	transmembrane transport
PotMrB4_RS05805	COG0747	negative chemotaxis
PotMrB4_RS05815	COG0747	negative chemotaxis
PotMrB4_RS05835	COG0747	negative chemotaxis
PotMrB4_RS05840	COG0747	negative chemotaxis
PotMrB4_RS05855	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PotMrB4_RS05865	COG4676	Protein conserved in bacteria
PotMrB4_RS05870	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PotMrB4_RS05885	COG5445	Predicted secreted protein (DUF2300)
PotMrB4_RS05890	COG4676	Protein conserved in bacteria
PotMrB4_RS05895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PotMrB4_RS05900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PotMrB4_RS05905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PotMrB4_RS05915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PotMrB4_RS05920	COG1077	Cell shape determining protein MreB Mrl
PotMrB4_RS05925	COG1792	Involved in formation and maintenance of cell shape
PotMrB4_RS05935	COG0424	maF-like protein
PotMrB4_RS05940	COG1530	ribonuclease E activity
PotMrB4_RS05950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PotMrB4_RS05955	COG0312	modulator of DNA gyrase
PotMrB4_RS05965	COG0312	modulator of DNA gyrase
PotMrB4_RS06000	COG1660	Displays ATPase and GTPase activities
PotMrB4_RS06015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PotMrB4_RS06020	COG1137	ATPase activity
PotMrB4_RS06025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PotMrB4_RS06035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PotMrB4_RS06045	COG1127	ABC transporter
PotMrB4_RS06050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PotMrB4_RS06055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PotMrB4_RS06080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PotMrB4_RS06090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PotMrB4_RS06095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PotMrB4_RS06105	COG0175	sulfate reduction
PotMrB4_RS06130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PotMrB4_RS06145	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS06150	COG1515	deoxyribonuclease V activity
PotMrB4_RS06155	COG0667	Aldo Keto reductase
PotMrB4_RS06160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PotMrB4_RS06165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PotMrB4_RS06170	COG0723	plastoquinol--plastocyanin reductase activity
PotMrB4_RS06175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PotMrB4_RS06180	COG2857	Cytochrome c1
PotMrB4_RS06185	COG0625	glutathione transferase activity
PotMrB4_RS06190	COG2969	positive regulation of protein catabolic process
PotMrB4_RS06195	COG2823	Periplasmic or secreted lipoprotein
PotMrB4_RS06205	COG0792	nuclease activity
PotMrB4_RS06210	COG3107	peptidoglycan biosynthetic process
PotMrB4_RS06245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PotMrB4_RS06250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PotMrB4_RS06255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PotMrB4_RS06260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PotMrB4_RS06265	COG0772	Belongs to the SEDS family
PotMrB4_RS06270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PotMrB4_RS06275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PotMrB4_RS06280	COG1181	Belongs to the D-alanine--D-alanine ligase family
PotMrB4_RS06310	COG0739	heme binding
PotMrB4_RS06330	COG0352	thiamine-phosphate diphosphorylase activity
PotMrB4_RS06340	COG2096	Adenosyltransferase
PotMrB4_RS06355	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS06365	COG0668	transmembrane transport
PotMrB4_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS06395	COG3030	protein affecting phage T7 exclusion by the F plasmid
PotMrB4_RS06400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PotMrB4_RS06405	COG0459	protein refolding
PotMrB4_RS06410	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS06415	COG0642	Histidine kinase
PotMrB4_RS06425	COG3642	lipopolysaccharide core region biosynthetic process
PotMrB4_RS06430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PotMrB4_RS06435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS06465	COG1704	LemA family
PotMrB4_RS06495	COG0583	DNA-binding transcription factor activity
PotMrB4_RS06500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PotMrB4_RS06515	COG1902	pentaerythritol trinitrate reductase activity
PotMrB4_RS06520	COG2814	Major facilitator Superfamily
PotMrB4_RS06535	COG0589	response to stress
PotMrB4_RS06555	COG3501	Rhs element vgr protein
PotMrB4_RS06600	COG1473	amidohydrolase
PotMrB4_RS06610	COG0154	amidase activity
PotMrB4_RS06630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PotMrB4_RS06640	COG0693	protein deglycase activity
PotMrB4_RS06670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PotMrB4_RS06670	COG3153	acetyltransferase
PotMrB4_RS06695	COG3706	GGDEF domain
PotMrB4_RS06740	COG0714	Associated with various cellular activities
PotMrB4_RS06770	COG2925	Exonuclease
PotMrB4_RS06780	COG0788	formyltetrahydrofolate deformylase activity
PotMrB4_RS06800	COG0306	phosphate transporter
PotMrB4_RS06810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS06815	COG0348	domain, Protein
PotMrB4_RS06840	COG1196	nuclear chromosome segregation
PotMrB4_RS06845	COG1074	ATP-dependent DNA helicase activity
PotMrB4_RS06860	COG1686	Belongs to the peptidase S11 family
PotMrB4_RS06915	COG1073	alpha beta
PotMrB4_RS06935	COG0789	Transcriptional regulator
PotMrB4_RS06950	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PotMrB4_RS06955	COG0563	adenylate kinase activity
PotMrB4_RS06960	COG1214	PFAM Peptidase M22, glycoprotease
PotMrB4_RS06970	COG1801	Protein of unknown function DUF72
PotMrB4_RS06990	COG2124	cytochrome p450
PotMrB4_RS07000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS07015	COG0418	dihydroorotase activity
PotMrB4_RS07025	COG0137	argininosuccinate synthase activity
PotMrB4_RS07030	COG0346	lactoylglutathione lyase activity
PotMrB4_RS07040	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PotMrB4_RS07050	COG2937	Belongs to the GPAT DAPAT family
PotMrB4_RS07055	COG1131	(ABC) transporter
PotMrB4_RS07085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PotMrB4_RS07090	COG4660	Part of a membrane complex involved in electron transport
PotMrB4_RS07095	COG4659	FMN binding
PotMrB4_RS07105	COG2878	Part of a membrane complex involved in electron transport
PotMrB4_RS07110	COG4657	Part of a membrane complex involved in electron transport
PotMrB4_RS07125	COG0489	protein tyrosine kinase activity
PotMrB4_RS07145	COG2205	protein histidine kinase activity
PotMrB4_RS07145	COG2198	Histidine kinase
PotMrB4_RS07145	COG0784	Response regulator, receiver
PotMrB4_RS07165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PotMrB4_RS07170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PotMrB4_RS07180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PotMrB4_RS07190	COG1113	amino acid transport
PotMrB4_RS07215	COG1201	RNA secondary structure unwinding
PotMrB4_RS07220	COG1793	dna ligase
PotMrB4_RS07225	COG1793	dna ligase
PotMrB4_RS07225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PotMrB4_RS07240	COG0625	glutathione transferase activity
PotMrB4_RS07245	COG0653	protein targeting
PotMrB4_RS07265	COG3012	SEC-C Motif Domain Protein
PotMrB4_RS07300	COG1199	ATP-dependent helicase activity
PotMrB4_RS07320	COG0259	pyridoxamine-phosphate oxidase activity
PotMrB4_RS07335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PotMrB4_RS07335	COG2111	Na H antiporter
PotMrB4_RS07340	COG1006	Multisubunit Na H antiporter MnhC subunit
PotMrB4_RS07345	COG0651	ATP synthesis coupled electron transport
PotMrB4_RS07350	COG1863	multisubunit Na H antiporter MnhE subunit
PotMrB4_RS07355	COG2212	antiporter activity
PotMrB4_RS07360	COG1320	monovalent cation:proton antiporter activity
PotMrB4_RS07365	COG0697	spore germination
PotMrB4_RS07385	COG3189	MarR family transcriptional regulator
PotMrB4_RS07435	COG2084	Dehydrogenase
PotMrB4_RS07440	COG3622	Belongs to the hyi family
PotMrB4_RS07450	COG2271	Major facilitator Superfamily
PotMrB4_RS07455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PotMrB4_RS07475	COG1289	transmembrane transporter activity
PotMrB4_RS07490	COG2030	dehydratase
PotMrB4_RS07495	COG2267	carboxylic ester hydrolase activity
PotMrB4_RS07500	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS07515	COG1643	Atp-dependent helicase
PotMrB4_RS07535	COG3706	GGDEF domain
PotMrB4_RS07540	COG0537	adenosine 5'-monophosphoramidase activity
PotMrB4_RS07575	COG1132	(ABC) transporter
PotMrB4_RS07585	COG0596	Alpha beta hydrolase
PotMrB4_RS07600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PotMrB4_RS07610	COG1051	belongs to the nudix hydrolase family
PotMrB4_RS07615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PotMrB4_RS07620	COG0513	Belongs to the DEAD box helicase family
PotMrB4_RS07675	COG2996	Protein conserved in bacteria
PotMrB4_RS07705	COG1278	Cold shock
PotMrB4_RS07710	COG0242	peptide deformylase activity
PotMrB4_RS07730	COG0631	protein serine/threonine phosphatase activity
PotMrB4_RS07735	COG2815	serine threonine protein kinase
PotMrB4_RS07735	COG0515	serine threonine protein kinase
PotMrB4_RS07770	COG5265	(ABC) transporter
PotMrB4_RS07780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PotMrB4_RS07805	COG0217	transcriptional regulatory protein
PotMrB4_RS07810	COG2249	NAD(P)H dehydrogenase (quinone) activity
PotMrB4_RS07845	COG0789	Transcriptional regulator
PotMrB4_RS07855	COG0583	DNA-binding transcription factor activity
PotMrB4_RS07860	COG2249	NAD(P)H dehydrogenase (quinone) activity
PotMrB4_RS07865	COG3257	ureidoglycine aminohydrolase activity
PotMrB4_RS07880	COG4206	TonB-dependent receptor
PotMrB4_RS07890	COG0583	DNA-binding transcription factor activity
PotMrB4_RS07895	COG2046	Belongs to the sulfate adenylyltransferase family
PotMrB4_RS07905	COG1943	Transposase
PotMrB4_RS07915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PotMrB4_RS07925	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS07930	COG2205	protein histidine kinase activity
PotMrB4_RS08025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PotMrB4_RS08030	COG0481	GTPase activity
PotMrB4_RS08045	COG0571	ribonuclease III activity
PotMrB4_RS08050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PotMrB4_RS08055	COG1381	Involved in DNA repair and RecF pathway recombination
PotMrB4_RS08065	COG0500	methyltransferase
PotMrB4_RS08070	COG2226	methyltransferase
PotMrB4_RS08085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PotMrB4_RS08100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PotMrB4_RS08115	COG4251	negative regulation of phosphorylation
PotMrB4_RS08115	COG3706	GGDEF domain
PotMrB4_RS08115	COG2203	Gaf domain
PotMrB4_RS08115	COG5001	Diguanylate cyclase
PotMrB4_RS08120	COG2205	protein histidine kinase activity
PotMrB4_RS08135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PotMrB4_RS08145	COG0477	Major facilitator Superfamily
PotMrB4_RS08150	COG2076	Multidrug Resistance protein
PotMrB4_RS08155	COG0385	Bile acid
PotMrB4_RS08160	COG2974	May be involved in recombination
PotMrB4_RS08175	COG0545	Peptidyl-prolyl cis-trans isomerase
PotMrB4_RS08230	COG2249	NAD(P)H dehydrogenase (quinone) activity
PotMrB4_RS08235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PotMrB4_RS08250	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS08260	COG1022	Amp-dependent synthetase and ligase
PotMrB4_RS08265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PotMrB4_RS08285	COG3130	regulation of translation
PotMrB4_RS08290	COG0116	Belongs to the methyltransferase superfamily
PotMrB4_RS08290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PotMrB4_RS08300	COG2027	D-alanyl-D-alanine carboxypeptidase
PotMrB4_RS08305	COG3171	Protein conserved in bacteria
PotMrB4_RS08310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PotMrB4_RS08315	COG2197	response regulator
PotMrB4_RS08330	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PotMrB4_RS08350	COG0004	ammonium transporteR
PotMrB4_RS08365	COG2010	Cytochrome c
PotMrB4_RS08365	COG4993	Dehydrogenase
PotMrB4_RS08375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PotMrB4_RS08380	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS08395	COG3971	2-oxopent-4-enoate hydratase activity
PotMrB4_RS08400	COG2271	Major facilitator Superfamily
PotMrB4_RS08410	COG3384	dioxygenase
PotMrB4_RS08415	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS08425	COG0179	Fumarylacetoacetate (FAA) hydrolase
PotMrB4_RS08430	COG1846	Transcriptional regulator
PotMrB4_RS08440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PotMrB4_RS08450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PotMrB4_RS08465	COG2814	Major facilitator Superfamily
PotMrB4_RS08475	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS08480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PotMrB4_RS08515	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PotMrB4_RS08520	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PotMrB4_RS08530	COG0535	radical SAM domain protein
PotMrB4_RS08565	COG0784	Response regulator, receiver
PotMrB4_RS08565	COG2205	protein histidine kinase activity
PotMrB4_RS08565	COG2198	Histidine kinase
PotMrB4_RS08585	COG0746	molybdenum cofactor guanylyltransferase activity
PotMrB4_RS08590	COG0521	Mo-molybdopterin cofactor biosynthetic process
PotMrB4_RS08595	COG0303	'Molybdopterin
PotMrB4_RS08605	COG0277	FAD linked oxidase domain protein
PotMrB4_RS08605	COG0277	FAD linked oxidase domain protein
PotMrB4_RS08610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PotMrB4_RS08615	COG1070	Carbohydrate kinase
PotMrB4_RS08640	COG0741	lytic transglycosylase activity
PotMrB4_RS08655	COG0589	response to stress
PotMrB4_RS08670	COG1024	Enoyl-CoA hydratase
PotMrB4_RS08670	COG1250	3-hydroxyacyl-CoA dehydrogenase
PotMrB4_RS08675	COG0183	Belongs to the thiolase family
PotMrB4_RS08705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PotMrB4_RS08730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PotMrB4_RS08740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PotMrB4_RS08750	COG1113	amino acid transport
PotMrB4_RS08760	COG1805	sodium ion transport
PotMrB4_RS08785	COG1477	protein flavinylation
PotMrB4_RS08795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PotMrB4_RS08800	COG0584	glycerophosphoryl diester phosphodiesterase
PotMrB4_RS08815	COG4591	ABC-type transport system involved in lipoprotein release permease component
PotMrB4_RS08825	COG4591	ABC-type transport system involved in lipoprotein release permease component
PotMrB4_RS08835	COG2333	competence protein COMEC
PotMrB4_RS08835	COG0658	competence protein
PotMrB4_RS08840	COG0811	peptide transport
PotMrB4_RS08845	COG0848	biopolymer transport protein
PotMrB4_RS08850	COG1663	tetraacyldisaccharide 4'-kinase activity
PotMrB4_RS08855	COG2835	tetraacyldisaccharide 4'-kinase activity
PotMrB4_RS08860	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PotMrB4_RS08865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PotMrB4_RS08870	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PotMrB4_RS08880	COG2304	oxidoreductase activity
PotMrB4_RS08885	COG1595	DNA-templated transcription, initiation
PotMrB4_RS08910	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS08925	COG1024	Enoyl-CoA hydratase
PotMrB4_RS08930	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS08935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PotMrB4_RS08950	COG1309	transcriptional regulator
PotMrB4_RS08980	COG1280	lysine exporter protein (LysE YggA)
PotMrB4_RS09025	COG0542	response to heat
PotMrB4_RS09035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PotMrB4_RS09065	COG2205	protein histidine kinase activity
PotMrB4_RS09070	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS09100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PotMrB4_RS09110	COG0714	Associated with various cellular activities
PotMrB4_RS09135	COG3706	GGDEF domain
PotMrB4_RS09155	COG0084	hydrolase, TatD family'
PotMrB4_RS09160	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PotMrB4_RS09165	COG2259	Doxx family
PotMrB4_RS09205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PotMrB4_RS09210	COG4181	ATPase activity
PotMrB4_RS09225	COG1376	ErfK ybiS ycfS ynhG family protein
PotMrB4_RS09260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PotMrB4_RS09270	COG0589	response to stress
PotMrB4_RS09300	COG2909	trisaccharide binding
PotMrB4_RS09305	COG2909	trisaccharide binding
PotMrB4_RS09345	COG4067	protein conserved in archaea
PotMrB4_RS09345	COG0189	ligase activity
PotMrB4_RS09350	COG1802	Transcriptional regulator
PotMrB4_RS09375	COG1280	lysine exporter protein (LysE YggA)
PotMrB4_RS09380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PotMrB4_RS09395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PotMrB4_RS09410	COG0668	transmembrane transport
PotMrB4_RS09440	COG0436	Aminotransferase
PotMrB4_RS09470	COG0589	response to stress
PotMrB4_RS09490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PotMrB4_RS09500	COG0215	cysteine-tRNA ligase activity
PotMrB4_RS09520	COG3552	Protein containing von Willebrand factor type A (VWA) domain
PotMrB4_RS09530	COG0714	Associated with various cellular activities
PotMrB4_RS09540	COG1879	ABC-type sugar transport system periplasmic component
PotMrB4_RS09550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PotMrB4_RS09605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PotMrB4_RS09605	COG0316	Belongs to the HesB IscA family
PotMrB4_RS09625	COG3813	Protein conserved in bacteria
PotMrB4_RS09645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS09660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PotMrB4_RS09665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PotMrB4_RS09670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PotMrB4_RS09675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PotMrB4_RS09680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PotMrB4_RS09685	COG0072	phenylalanine-tRNA ligase activity
PotMrB4_RS09730	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS09760	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS09770	COG4191	Histidine kinase
PotMrB4_RS09775	COG4566	intracellular signal transduction
PotMrB4_RS09810	COG0720	synthase
PotMrB4_RS09815	COG3604	Transcriptional regulator
PotMrB4_RS09860	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS09885	COG0840	transmembrane signaling receptor activity
PotMrB4_RS09890	COG1968	undecaprenyl-diphosphatase activity
PotMrB4_RS09895	COG2267	carboxylic ester hydrolase activity
PotMrB4_RS09925	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PotMrB4_RS09930	COG0488	(ABC) transporter
PotMrB4_RS09940	COG0583	DNA-binding transcription factor activity
PotMrB4_RS09945	COG3706	GGDEF domain
PotMrB4_RS09955	COG1595	DNA-templated transcription, initiation
PotMrB4_RS09960	COG3712	iron ion homeostasis
PotMrB4_RS09975	COG0463	Glycosyl transferase, family 2
PotMrB4_RS09990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PotMrB4_RS10010	COG1250	3-hydroxyacyl-CoA dehydrogenase
PotMrB4_RS10010	COG1024	Enoyl-CoA hydratase
PotMrB4_RS10020	COG0402	S-adenosylhomocysteine deaminase activity
PotMrB4_RS10035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PotMrB4_RS10060	COG3115	cell septum assembly
PotMrB4_RS10065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PotMrB4_RS10085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PotMrB4_RS10090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PotMrB4_RS10105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PotMrB4_RS10115	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS10140	COG2274	protein secretion by the type I secretion system
PotMrB4_RS10145	COG3850	Histidine kinase
PotMrB4_RS10145	COG3437	response regulator, receiver
PotMrB4_RS10145	COG4999	Histidine kinase
PotMrB4_RS10145	COG2205	protein histidine kinase activity
PotMrB4_RS10175	COG2814	Major facilitator Superfamily
PotMrB4_RS10180	COG0583	DNA-binding transcription factor activity
PotMrB4_RS10185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PotMrB4_RS10190	COG0840	transmembrane signaling receptor activity
PotMrB4_RS10195	COG0506	proline dehydrogenase activity
PotMrB4_RS10195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PotMrB4_RS10195	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PotMrB4_RS10200	COG3530	Putative quorum-sensing-regulated virulence factor
PotMrB4_RS10235	COG3245	cytochrome
PotMrB4_RS10295	COG1126	abc transporter atp-binding protein
PotMrB4_RS10300	COG0765	amino acid transport
PotMrB4_RS10305	COG0765	amino acid transport
PotMrB4_RS10310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS10320	COG3842	ATPase activity
PotMrB4_RS10330	COG1176	ABC-type spermidine putrescine transport system, permease component I
PotMrB4_RS10340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PotMrB4_RS10355	COG2186	Transcriptional regulator
PotMrB4_RS10360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PotMrB4_RS10365	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS10375	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS10380	COG2267	carboxylic ester hydrolase activity
PotMrB4_RS10410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PotMrB4_RS10415	COG0183	Belongs to the thiolase family
PotMrB4_RS10460	COG0326	Molecular chaperone. Has ATPase activity
PotMrB4_RS10495	COG2207	Transcriptional regulator
PotMrB4_RS10510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PotMrB4_RS10525	COG0028	Belongs to the TPP enzyme family
PotMrB4_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS10560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PotMrB4_RS10565	COG3971	2-oxopent-4-enoate hydratase activity
PotMrB4_RS10575	COG1940	carbohydrate kinase activity
PotMrB4_RS10580	COG0583	DNA-binding transcription factor activity
PotMrB4_RS10590	COG2207	Transcriptional regulator
PotMrB4_RS10600	COG1741	Belongs to the pirin family
PotMrB4_RS10640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PotMrB4_RS10645	COG1538	Outer membrane efflux protein
PotMrB4_RS10670	COG2132	Multicopper oxidase
PotMrB4_RS10680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PotMrB4_RS10680	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PotMrB4_RS10700	COG2853	Lipoprotein
PotMrB4_RS10710	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS10720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PotMrB4_RS10765	COG0587	DNA-directed DNA polymerase activity
PotMrB4_RS10780	COG3706	GGDEF domain
PotMrB4_RS10785	COG1045	serine acetyltransferase
PotMrB4_RS10790	COG5006	permease, DMT superfamily
PotMrB4_RS10815	COG0753	catalase activity
PotMrB4_RS10830	COG0431	NADPH-dependent FMN reductase
PotMrB4_RS10835	COG0840	transmembrane signaling receptor activity
PotMrB4_RS10840	COG2056	Na+-H+ antiporter family
PotMrB4_RS10860	COG1007	ATP synthesis coupled electron transport
PotMrB4_RS10875	COG0713	ATP synthesis coupled electron transport
PotMrB4_RS10885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PotMrB4_RS10890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PotMrB4_RS10915	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PotMrB4_RS10920	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PotMrB4_RS10955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS10960	COG0842	Transport permease protein
PotMrB4_RS10960	COG1129	ABC transporter
PotMrB4_RS10965	COG0842	Transport permease protein
PotMrB4_RS10970	COG0583	DNA-binding transcription factor activity
PotMrB4_RS10975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PotMrB4_RS10980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PotMrB4_RS10990	COG2031	fatty acid transporter
PotMrB4_RS11015	COG4191	Histidine kinase
PotMrB4_RS11015	COG0784	Response regulator, receiver
PotMrB4_RS11040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PotMrB4_RS11045	COG5002	protein histidine kinase activity
PotMrB4_RS11045	COG2205	protein histidine kinase activity
PotMrB4_RS11045	COG0784	Response regulator, receiver
PotMrB4_RS11050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PotMrB4_RS11075	COG1022	Amp-dependent synthetase and ligase
PotMrB4_RS11085	COG0708	Exodeoxyribonuclease III
PotMrB4_RS11095	COG0729	surface antigen
PotMrB4_RS11100	COG2911	Protein conserved in bacteria
PotMrB4_RS11125	COG0439	Biotin carboxylase
PotMrB4_RS11135	COG3665	Urea carboxylase-associated protein
PotMrB4_RS11140	COG1116	anion transmembrane transporter activity
PotMrB4_RS11180	COG1917	Cupin 2, conserved barrel domain protein
PotMrB4_RS11180	COG2207	Transcriptional regulator
PotMrB4_RS11190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PotMrB4_RS11200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PotMrB4_RS11220	COG4251	negative regulation of phosphorylation
PotMrB4_RS11220	COG3706	GGDEF domain
PotMrB4_RS11220	COG2203	Gaf domain
PotMrB4_RS11220	COG5001	Diguanylate cyclase
PotMrB4_RS11225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PotMrB4_RS11225	COG0116	Belongs to the methyltransferase superfamily
PotMrB4_RS11240	COG1538	Outer membrane efflux protein
PotMrB4_RS11245	COG2274	protein secretion by the type I secretion system
PotMrB4_RS11250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS11255	COG0590	tRNA wobble adenosine to inosine editing
PotMrB4_RS11270	COG0477	Major facilitator Superfamily
PotMrB4_RS11305	COG2207	Transcriptional regulator
PotMrB4_RS11335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PotMrB4_RS11345	COG0583	DNA-binding transcription factor activity
PotMrB4_RS11365	COG1464	Belongs to the NlpA lipoprotein family
PotMrB4_RS11375	COG2011	ABC-type metal ion transport system permease component
PotMrB4_RS11380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS11385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PotMrB4_RS11390	COG1116	anion transmembrane transporter activity
PotMrB4_RS11405	COG5002	protein histidine kinase activity
PotMrB4_RS11405	COG2205	protein histidine kinase activity
PotMrB4_RS11405	COG0784	Response regulator, receiver
PotMrB4_RS11430	COG2153	protein acetylation
PotMrB4_RS11435	COG2850	peptidyl-arginine hydroxylation
PotMrB4_RS11445	COG2915	High frequency lysogenization protein hflD homolog
PotMrB4_RS11450	COG0482	sulfurtransferase activity
PotMrB4_RS11470	COG1278	Cold shock
PotMrB4_RS11475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PotMrB4_RS11480	COG0542	response to heat
PotMrB4_RS11485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PotMrB4_RS11490	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PotMrB4_RS11495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PotMrB4_RS11500	COG0492	ferredoxin-NADP+ reductase activity
PotMrB4_RS11510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PotMrB4_RS11515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PotMrB4_RS11520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PotMrB4_RS11530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PotMrB4_RS11530	COG1648	precorrin-2 dehydrogenase activity
PotMrB4_RS11535	COG0435	Glutathione S-transferase
PotMrB4_RS11540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PotMrB4_RS11545	COG2920	part of a sulfur-relay system
PotMrB4_RS11650	COG2135	peptidase activity
PotMrB4_RS11875	COG3179	chitinase
PotMrB4_RS11895	COG1278	Cold shock
PotMrB4_RS11985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PotMrB4_RS12045	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS12075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PotMrB4_RS12085	COG5001	Diguanylate cyclase
PotMrB4_RS12085	COG3300	MHYT domain
PotMrB4_RS12095	COG2706	6-phosphogluconolactonase activity
PotMrB4_RS12130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PotMrB4_RS12135	COG0835	chemotaxis
PotMrB4_RS12140	COG0840	transmembrane signaling receptor activity
PotMrB4_RS12145	COG2198	Histidine kinase
PotMrB4_RS12145	COG0643	Histidine kinase
PotMrB4_RS12155	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS12165	COG1653	transport
PotMrB4_RS12170	COG1175	transmembrane transport
PotMrB4_RS12175	COG0395	ABC-type sugar transport system, permease component
PotMrB4_RS12180	COG3842	ATPase activity
PotMrB4_RS12185	COG4580	involved in the transport of maltose and maltodextrins
PotMrB4_RS12190	COG0676	glucose-6-phosphate 1-epimerase activity
PotMrB4_RS12195	COG1737	Transcriptional regulator
PotMrB4_RS12210	COG0800	Aldolase
PotMrB4_RS12225	COG1609	Transcriptional regulator
PotMrB4_RS12235	COG1105	Belongs to the carbohydrate kinase PfkB family
PotMrB4_RS12240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PotMrB4_RS12240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PotMrB4_RS12240	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PotMrB4_RS12245	COG0583	DNA-binding transcription factor activity
PotMrB4_RS12265	COG1566	PFAM secretion protein HlyD family protein
PotMrB4_RS12270	COG3089	Belongs to the UPF0270 family
PotMrB4_RS12275	COG2205	protein histidine kinase activity
PotMrB4_RS12275	COG5002	protein histidine kinase activity
PotMrB4_RS12275	COG0784	Response regulator, receiver
PotMrB4_RS12280	COG1363	Peptidase, m42
PotMrB4_RS12285	COG1181	Belongs to the D-alanine--D-alanine ligase family
PotMrB4_RS12290	COG0367	asparagine synthase
PotMrB4_RS12295	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PotMrB4_RS12295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS12305	COG1024	Enoyl-CoA hydratase
PotMrB4_RS12310	COG1024	Enoyl-CoA hydratase
PotMrB4_RS12315	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS12335	COG2720	vancomycin resistance protein
PotMrB4_RS12340	COG2249	NAD(P)H dehydrogenase (quinone) activity
PotMrB4_RS12360	COG0271	Belongs to the BolA IbaG family
PotMrB4_RS12365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PotMrB4_RS12380	COG0543	2 iron, 2 sulfur cluster binding
PotMrB4_RS12380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PotMrB4_RS12385	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PotMrB4_RS12390	COG4638	Rieske (2fe-2S)
PotMrB4_RS12405	COG0604	alcohol dehydrogenase
PotMrB4_RS12410	COG1309	transcriptional regulator
PotMrB4_RS12450	COG1611	Belongs to the LOG family
PotMrB4_RS12460	COG0417	DNA replication proofreading
PotMrB4_RS12480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS12480	COG2205	protein histidine kinase activity
PotMrB4_RS12500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PotMrB4_RS12505	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS12505	COG2030	dehydratase
PotMrB4_RS12520	COG3162	membrane
PotMrB4_RS12525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PotMrB4_RS12530	COG2151	metal-sulfur cluster biosynthetic enzyme
PotMrB4_RS12535	COG3396	Phenylacetate-CoA oxygenase
PotMrB4_RS12540	COG3460	Phenylacetate-CoA oxygenase
PotMrB4_RS12545	COG3396	Phenylacetate-CoA oxygenase
PotMrB4_RS12560	COG3501	Rhs element vgr protein
PotMrB4_RS12635	COG5507	3-demethylubiquinone-9 3-methyltransferase
PotMrB4_RS12655	COG0183	Belongs to the thiolase family
PotMrB4_RS12660	COG2050	protein possibly involved in aromatic compounds catabolism
PotMrB4_RS12665	COG1250	3-hydroxyacyl-CoA dehydrogenase
PotMrB4_RS12670	COG1024	Enoyl-CoA hydratase
PotMrB4_RS12675	COG1024	Enoyl-CoA hydratase
PotMrB4_RS12685	COG3327	negative regulation of DNA-templated transcription, initiation
PotMrB4_RS12715	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS12730	COG0583	DNA-binding transcription factor activity
PotMrB4_RS12735	COG0784	Response regulator, receiver
PotMrB4_RS12735	COG4191	Histidine kinase
PotMrB4_RS12765	COG2831	hemolysin activation secretion protein
PotMrB4_RS12780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PotMrB4_RS12785	COG2318	DinB family
PotMrB4_RS12795	COG2378	regulation of single-species biofilm formation
PotMrB4_RS12810	COG0786	glutamate:sodium symporter activity
PotMrB4_RS12815	COG1335	isochorismatase
PotMrB4_RS12820	COG1764	response to oxidative stress
PotMrB4_RS12835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PotMrB4_RS12840	COG0626	cystathionine gamma-synthase activity
PotMrB4_RS12845	COG0833	amino acid
PotMrB4_RS12850	COG0583	DNA-binding transcription factor activity
PotMrB4_RS12860	COG1522	sequence-specific DNA binding
PotMrB4_RS12870	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS12885	COG2207	Transcriptional regulator
PotMrB4_RS12885	COG1917	Cupin 2, conserved barrel domain protein
PotMrB4_RS12890	COG1335	isochorismatase
PotMrB4_RS12895	COG4566	intracellular signal transduction
PotMrB4_RS12900	COG4566	intracellular signal transduction
PotMrB4_RS12900	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS12915	COG0583	DNA-binding transcription factor activity
PotMrB4_RS12920	COG2828	Protein conserved in bacteria
PotMrB4_RS12925	COG2851	Citrate transporter
PotMrB4_RS12935	COG0861	Integral membrane protein TerC family
PotMrB4_RS12980	COG1064	alcohol dehydrogenase
PotMrB4_RS13000	COG3706	GGDEF domain
PotMrB4_RS13000	COG2203	Gaf domain
PotMrB4_RS13000	COG4251	negative regulation of phosphorylation
PotMrB4_RS13000	COG5001	Diguanylate cyclase
PotMrB4_RS13010	COG4106	trans-aconitate 2-methyltransferase activity
PotMrB4_RS13050	COG1696	Membrane protein involved in D-alanine export
PotMrB4_RS13070	COG1215	transferase activity, transferring glycosyl groups
PotMrB4_RS13190	COG0531	amino acid
PotMrB4_RS13195	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PotMrB4_RS13200	COG3938	Belongs to the proline racemase family
PotMrB4_RS13205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PotMrB4_RS13225	COG3729	General stress protein
PotMrB4_RS13245	COG1285	pathogenesis
PotMrB4_RS13265	COG0789	Transcriptional regulator
PotMrB4_RS13280	COG0765	amino acid transport
PotMrB4_RS13290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS13300	COG0583	DNA-binding transcription factor activity
PotMrB4_RS13310	COG0659	secondary active sulfate transmembrane transporter activity
PotMrB4_RS13320	COG4948	Mandelate Racemase Muconate Lactonizing
PotMrB4_RS13325	COG4829	muconolactone delta-isomerase
PotMrB4_RS13330	COG3485	protocatechuate 3,4-dioxygenase
PotMrB4_RS13370	COG0642	Histidine kinase
PotMrB4_RS13390	COG0243	molybdopterin cofactor binding
PotMrB4_RS13395	COG2146	nitrite reductase [NAD(P)H] activity
PotMrB4_RS13400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PotMrB4_RS13405	COG2815	serine threonine protein kinase
PotMrB4_RS13405	COG0515	serine threonine protein kinase
PotMrB4_RS13410	COG2223	nitrite transmembrane transporter activity
PotMrB4_RS13415	COG3707	response regulator
PotMrB4_RS13420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS13430	COG1196	nuclear chromosome segregation
PotMrB4_RS13450	COG0826	peptidase U32
PotMrB4_RS13460	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PotMrB4_RS13475	COG3483	tryptophan 2,3-dioxygenase activity
PotMrB4_RS13495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PotMrB4_RS13515	COG1132	(ABC) transporter
PotMrB4_RS13520	COG1132	(ABC) transporter
PotMrB4_RS13525	COG4771	TonB-dependent receptor
PotMrB4_RS13545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS13615	COG3397	chitin binding
PotMrB4_RS13640	COG3501	Rhs element vgr protein
PotMrB4_RS13645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PotMrB4_RS13660	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS13685	COG0583	DNA-binding transcription factor activity
PotMrB4_RS13715	COG3842	ATPase activity
PotMrB4_RS13720	COG1178	ABC-type Fe3 transport system permease component
PotMrB4_RS13725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PotMrB4_RS13730	COG1840	ABC-type Fe3 transport system, periplasmic component
PotMrB4_RS13740	COG0842	Transport permease protein
PotMrB4_RS13745	COG1131	(ABC) transporter
PotMrB4_RS13750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS13760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PotMrB4_RS13800	COG0392	lysyltransferase activity
PotMrB4_RS13805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PotMrB4_RS13810	COG3568	Endonuclease Exonuclease Phosphatase
PotMrB4_RS13885	COG2233	PERMEase
PotMrB4_RS13895	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PotMrB4_RS13900	COG0709	Synthesizes selenophosphate from selenide and ATP
PotMrB4_RS13905	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PotMrB4_RS13910	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PotMrB4_RS13915	COG3639	organic phosphonate transmembrane transporter activity
PotMrB4_RS13980	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PotMrB4_RS14000	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS14020	COG2323	membrane
PotMrB4_RS14025	COG3685	Protein conserved in bacteria
PotMrB4_RS14040	COG1063	alcohol dehydrogenase
PotMrB4_RS14050	COG3685	Protein conserved in bacteria
PotMrB4_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS14075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PotMrB4_RS14080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS14145	COG3424	synthase
PotMrB4_RS14215	COG0583	DNA-binding transcription factor activity
PotMrB4_RS14220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PotMrB4_RS14225	COG1116	anion transmembrane transporter activity
PotMrB4_RS14230	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS14235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PotMrB4_RS14245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS14300	COG4285	Biotin-protein ligase, N terminal
PotMrB4_RS14305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PotMrB4_RS14310	COG3154	lipid carrier protein
PotMrB4_RS14315	COG0826	peptidase U32
PotMrB4_RS14320	COG0826	peptidase U32
PotMrB4_RS14340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS14365	COG0667	Aldo Keto reductase
PotMrB4_RS14370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PotMrB4_RS14385	COG0084	hydrolase, TatD family'
PotMrB4_RS14435	COG4251	negative regulation of phosphorylation
PotMrB4_RS14435	COG5001	Diguanylate cyclase
PotMrB4_RS14435	COG3706	GGDEF domain
PotMrB4_RS14435	COG2203	Gaf domain
PotMrB4_RS14445	COG0596	Alpha beta hydrolase
PotMrB4_RS14455	COG3655	Transcriptional regulator
PotMrB4_RS14465	COG0583	DNA-binding transcription factor activity
PotMrB4_RS14470	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS14475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PotMrB4_RS14480	COG3842	ATPase activity
PotMrB4_RS14485	COG1176	ABC-type spermidine putrescine transport system, permease component I
PotMrB4_RS14490	COG1177	transmembrane transport
PotMrB4_RS14495	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS14505	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PotMrB4_RS14510	COG5001	Diguanylate cyclase
PotMrB4_RS14510	COG3300	MHYT domain
PotMrB4_RS14520	COG0626	cystathionine gamma-synthase activity
PotMrB4_RS14540	COG1058	Belongs to the CinA family
PotMrB4_RS14540	COG1546	Belongs to the CinA family
PotMrB4_RS14545	COG0297	glycogen (starch) synthase activity
PotMrB4_RS14550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PotMrB4_RS14595	COG2203	Gaf domain
PotMrB4_RS14595	COG3706	GGDEF domain
PotMrB4_RS14595	COG4251	negative regulation of phosphorylation
PotMrB4_RS14595	COG5001	Diguanylate cyclase
PotMrB4_RS14600	COG0583	DNA-binding transcription factor activity
PotMrB4_RS14610	COG4771	TonB-dependent receptor
PotMrB4_RS14620	COG1858	cytochrome C peroxidase
PotMrB4_RS14660	COG3546	catalase activity
PotMrB4_RS14690	COG3245	cytochrome
PotMrB4_RS14745	COG1716	ATPase activity
PotMrB4_RS14745	COG5001	Diguanylate cyclase
PotMrB4_RS14760	COG2197	response regulator
PotMrB4_RS14765	COG2198	Histidine kinase
PotMrB4_RS14765	COG2205	protein histidine kinase activity
PotMrB4_RS14765	COG0784	Response regulator, receiver
PotMrB4_RS14780	COG4774	siderophore transport
PotMrB4_RS14805	COG2957	Belongs to the agmatine deiminase family
PotMrB4_RS14810	COG0583	DNA-binding transcription factor activity
PotMrB4_RS14830	COG3119	arylsulfatase activity
PotMrB4_RS14835	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS14840	COG0183	Belongs to the thiolase family
PotMrB4_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS14855	COG1024	Enoyl-CoA hydratase
PotMrB4_RS14860	COG2814	Major facilitator Superfamily
PotMrB4_RS14895	COG1309	transcriptional regulator
PotMrB4_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS14925	COG0583	DNA-binding transcription factor activity
PotMrB4_RS14940	COG4585	Histidine kinase
PotMrB4_RS14945	COG2197	response regulator
PotMrB4_RS14965	COG0643	Histidine kinase
PotMrB4_RS14965	COG2198	Histidine kinase
PotMrB4_RS14975	COG0840	transmembrane signaling receptor activity
PotMrB4_RS14980	COG0835	chemotaxis
PotMrB4_RS14990	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PotMrB4_RS14995	COG2201	protein-glutamate methylesterase activity
PotMrB4_RS15030	COG2067	long-chain fatty acid transport protein
PotMrB4_RS15050	COG1136	(ABC) transporter
PotMrB4_RS15050	COG0577	efflux transmembrane transporter activity
PotMrB4_RS15055	COG1136	(ABC) transporter
PotMrB4_RS15055	COG0577	efflux transmembrane transporter activity
PotMrB4_RS15090	COG0515	serine threonine protein kinase
PotMrB4_RS15090	COG2815	serine threonine protein kinase
PotMrB4_RS15185	COG3501	Rhs element vgr protein
PotMrB4_RS15190	COG0346	lactoylglutathione lyase activity
PotMrB4_RS15240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PotMrB4_RS15245	COG3501	Rhs element vgr protein
PotMrB4_RS15295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PotMrB4_RS15300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PotMrB4_RS15305	COG1309	transcriptional regulator
PotMrB4_RS15315	COG0477	Major facilitator Superfamily
PotMrB4_RS15325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PotMrB4_RS15355	COG0811	peptide transport
PotMrB4_RS15425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PotMrB4_RS15430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PotMrB4_RS15440	COG0183	Belongs to the thiolase family
PotMrB4_RS15445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PotMrB4_RS15450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PotMrB4_RS15525	COG0840	transmembrane signaling receptor activity
PotMrB4_RS15540	COG2116	formate transmembrane transporter activity
PotMrB4_RS15560	COG5001	Diguanylate cyclase
PotMrB4_RS15560	COG3300	MHYT domain
PotMrB4_RS15565	COG2204	response regulator
PotMrB4_RS15570	COG3437	response regulator, receiver
PotMrB4_RS15585	COG5002	protein histidine kinase activity
PotMrB4_RS15595	COG2201	protein-glutamate methylesterase activity
PotMrB4_RS15625	COG1368	sulfuric ester hydrolase activity
PotMrB4_RS15635	COG2239	Acts as a magnesium transporter
PotMrB4_RS15650	COG0477	Major facilitator Superfamily
PotMrB4_RS15660	COG0667	Aldo Keto reductase
PotMrB4_RS15675	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS15680	COG2223	nitrite transmembrane transporter activity
PotMrB4_RS15685	COG4948	Mandelate Racemase Muconate Lactonizing
PotMrB4_RS15700	COG0583	DNA-binding transcription factor activity
PotMrB4_RS15735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS15745	COG1538	Outer membrane efflux protein
PotMrB4_RS15755	COG1414	Transcriptional regulator
PotMrB4_RS15760	COG0679	Auxin Efflux Carrier
PotMrB4_RS15765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PotMrB4_RS15770	COG3485	protocatechuate 3,4-dioxygenase
PotMrB4_RS15775	COG3485	protocatechuate 3,4-dioxygenase
PotMrB4_RS15780	COG0583	DNA-binding transcription factor activity
PotMrB4_RS15795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PotMrB4_RS15805	COG2814	Major facilitator Superfamily
PotMrB4_RS15810	COG0583	DNA-binding transcription factor activity
PotMrB4_RS15820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PotMrB4_RS15830	COG3706	GGDEF domain
PotMrB4_RS15830	COG2203	Gaf domain
PotMrB4_RS15830	COG5001	Diguanylate cyclase
PotMrB4_RS15830	COG4251	negative regulation of phosphorylation
PotMrB4_RS15835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PotMrB4_RS15840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS15845	COG1116	anion transmembrane transporter activity
PotMrB4_RS15860	COG4977	sequence-specific DNA binding
PotMrB4_RS15860	COG1917	Cupin 2, conserved barrel domain protein
PotMrB4_RS15870	COG0058	SHG alpha-glucan phosphorylase activity
PotMrB4_RS15915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PotMrB4_RS15915	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PotMrB4_RS15920	COG1760	l-serine dehydratase
PotMrB4_RS15925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PotMrB4_RS15940	COG4191	Histidine kinase
PotMrB4_RS15940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS15945	COG0784	Response regulator, receiver
PotMrB4_RS15945	COG3437	response regulator, receiver
PotMrB4_RS15950	COG4178	(ABC) transporter
PotMrB4_RS16000	COG1132	(ABC) transporter
PotMrB4_RS16005	COG3284	Transcriptional regulator
PotMrB4_RS16015	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS16020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PotMrB4_RS16025	COG1250	3-hydroxyacyl-CoA dehydrogenase
PotMrB4_RS16025	COG1024	Enoyl-CoA hydratase
PotMrB4_RS16060	COG0789	Transcriptional regulator
PotMrB4_RS16065	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS16075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PotMrB4_RS16085	COG0842	Transport permease protein
PotMrB4_RS16090	COG1131	(ABC) transporter
PotMrB4_RS16095	COG0625	glutathione transferase activity
PotMrB4_RS16155	COG1956	GAF domain-containing protein
PotMrB4_RS16165	COG0784	Response regulator, receiver
PotMrB4_RS16165	COG2205	protein histidine kinase activity
PotMrB4_RS16165	COG5002	protein histidine kinase activity
PotMrB4_RS16170	COG1846	Transcriptional regulator
PotMrB4_RS16175	COG0386	Belongs to the glutathione peroxidase family
PotMrB4_RS16180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PotMrB4_RS16185	COG0436	Aminotransferase
PotMrB4_RS16190	COG0300	oxidoreductase activity
PotMrB4_RS16200	COG0501	Belongs to the peptidase M48B family
PotMrB4_RS16205	COG0500	methyltransferase
PotMrB4_RS16210	COG3384	dioxygenase
PotMrB4_RS16215	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PotMrB4_RS16225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PotMrB4_RS16250	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PotMrB4_RS16255	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PotMrB4_RS16260	COG0235	Class ii aldolase
PotMrB4_RS16270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PotMrB4_RS16290	COG1335	isochorismatase
PotMrB4_RS16300	COG2840	Smr protein MutS2
PotMrB4_RS16325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS16345	COG3135	benzoate transporter
PotMrB4_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS16355	COG2130	NADP-dependent
PotMrB4_RS16360	COG3214	Protein conserved in bacteria
PotMrB4_RS16380	COG0583	DNA-binding transcription factor activity
PotMrB4_RS16390	COG0583	DNA-binding transcription factor activity
PotMrB4_RS16400	COG1846	Transcriptional regulator
PotMrB4_RS16440	COG0069	glutamate synthase activity
PotMrB4_RS16445	COG0583	DNA-binding transcription factor activity
PotMrB4_RS16485	COG3766	membrane
PotMrB4_RS16495	COG0754	glutathionylspermidine amidase activity
PotMrB4_RS16515	COG3046	protein related to deoxyribodipyrimidine photolyase
PotMrB4_RS16550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PotMrB4_RS16560	COG1677	Flagellar hook-basal body complex protein FliE
PotMrB4_RS16585	COG1987	bacterial-type flagellum assembly
PotMrB4_RS16595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PotMrB4_RS16605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PotMrB4_RS16625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PotMrB4_RS16630	COG1191	sigma factor activity
PotMrB4_RS16655	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PotMrB4_RS16660	COG3501	Rhs element vgr protein
PotMrB4_RS16695	COG0741	lytic transglycosylase activity
PotMrB4_RS16700	COG1706	bacterial-type flagellum-dependent cell motility
PotMrB4_RS16710	COG4786	Flagellar basal body rod
PotMrB4_RS16715	COG4787	bacterial-type flagellum-dependent cell motility
PotMrB4_RS16720	COG4786	Flagellar basal body rod
PotMrB4_RS16725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PotMrB4_RS16730	COG1558	bacterial-type flagellum-dependent cell motility
PotMrB4_RS16745	COG3300	MHYT domain
PotMrB4_RS16745	COG5001	Diguanylate cyclase
PotMrB4_RS16755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PotMrB4_RS16765	COG2233	PERMEase
PotMrB4_RS16775	COG2351	hydroxyisourate hydrolase activity
PotMrB4_RS16780	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PotMrB4_RS16800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PotMrB4_RS16805	COG0179	Fumarylacetoacetate (FAA) hydrolase
PotMrB4_RS16845	COG0564	pseudouridine synthase activity
PotMrB4_RS16855	COG2010	Cytochrome c
PotMrB4_RS16860	COG0753	catalase activity
PotMrB4_RS16885	COG0662	Cupin 2, conserved barrel domain protein
PotMrB4_RS16895	COG2866	Carboxypeptidase
PotMrB4_RS16910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PotMrB4_RS16945	COG0583	DNA-binding transcription factor activity
PotMrB4_RS16965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PotMrB4_RS16985	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PotMrB4_RS16995	COG0840	transmembrane signaling receptor activity
PotMrB4_RS17030	COG0583	DNA-binding transcription factor activity
PotMrB4_RS17040	COG0625	glutathione transferase activity
PotMrB4_RS17045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PotMrB4_RS17045	COG1017	nitric oxide dioxygenase activity
PotMrB4_RS17070	COG1760	l-serine dehydratase
PotMrB4_RS17085	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS17105	COG1515	deoxyribonuclease V activity
PotMrB4_RS17115	COG2203	Gaf domain
PotMrB4_RS17115	COG2199	diguanylate cyclase activity
PotMrB4_RS17125	COG1335	isochorismatase
PotMrB4_RS17145	COG4221	oxidoreductase activity
PotMrB4_RS17155	COG1595	DNA-templated transcription, initiation
PotMrB4_RS17195	COG1063	alcohol dehydrogenase
PotMrB4_RS17205	COG0022	dehydrogenase e1 component
PotMrB4_RS17210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PotMrB4_RS17215	COG3199	ATP-NAD kinase
PotMrB4_RS17220	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS17225	COG3284	Transcriptional regulator
PotMrB4_RS17240	COG1113	amino acid transport
PotMrB4_RS17255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PotMrB4_RS17260	COG1522	sequence-specific DNA binding
PotMrB4_RS17270	COG3278	Belongs to the heme-copper respiratory oxidase family
PotMrB4_RS17290	COG3278	Belongs to the heme-copper respiratory oxidase family
PotMrB4_RS17305	COG2010	Cytochrome c
PotMrB4_RS17310	COG0348	domain, Protein
PotMrB4_RS17345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PotMrB4_RS17350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PotMrB4_RS17385	COG0492	ferredoxin-NADP+ reductase activity
PotMrB4_RS17390	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PotMrB4_RS17405	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS17420	COG5339	Protein conserved in bacteria
PotMrB4_RS17425	COG0628	permease
PotMrB4_RS17435	COG0625	glutathione transferase activity
PotMrB4_RS17455	COG1280	lysine exporter protein (LysE YggA)
PotMrB4_RS17460	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PotMrB4_RS17480	COG4774	siderophore transport
PotMrB4_RS17485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PotMrB4_RS17495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PotMrB4_RS17500	COG2807	transmembrane transport
PotMrB4_RS17505	COG2186	Transcriptional regulator
PotMrB4_RS17525	COG1309	transcriptional regulator
PotMrB4_RS17550	COG0642	Histidine kinase
PotMrB4_RS17555	COG2194	sulfuric ester hydrolase activity
PotMrB4_RS17570	COG1305	Transglutaminase-like
PotMrB4_RS17580	COG2308	Evidence 4 Homologs of previously reported genes of
PotMrB4_RS17585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PotMrB4_RS17585	COG0519	Catalyzes the synthesis of GMP from XMP
PotMrB4_RS17590	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS17600	COG2072	flavoprotein involved in K transport
PotMrB4_RS17695	COG0598	Magnesium transport protein CorA
PotMrB4_RS17700	COG0519	Catalyzes the synthesis of GMP from XMP
PotMrB4_RS17730	COG0045	succinate-CoA ligase (ADP-forming) activity
PotMrB4_RS17750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PotMrB4_RS17755	COG1053	succinate dehydrogenase
PotMrB4_RS17760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PotMrB4_RS17765	COG2009	succinate dehydrogenase
PotMrB4_RS17795	COG2084	Dehydrogenase
PotMrB4_RS17805	COG3123	guanosine phosphorylase activity
PotMrB4_RS17815	COG1132	(ABC) transporter
PotMrB4_RS17825	COG3011	Protein conserved in bacteria
PotMrB4_RS17830	COG3738	Protein conserved in bacteria
PotMrB4_RS17850	COG2186	Transcriptional regulator
PotMrB4_RS17860	COG2252	PERMEase
PotMrB4_RS17900	COG2233	PERMEase
PotMrB4_RS17925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PotMrB4_RS17930	COG1309	transcriptional regulator
PotMrB4_RS17945	COG3960	tartronate-semialdehyde synthase activity
PotMrB4_RS17950	COG3622	Belongs to the hyi family
PotMrB4_RS17955	COG2084	Dehydrogenase
PotMrB4_RS17965	COG0469	pyruvate kinase activity
PotMrB4_RS17970	COG4413	Urea transporter
PotMrB4_RS17980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PotMrB4_RS18025	COG1138	Cytochrome C-type biogenesis protein
PotMrB4_RS18030	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PotMrB4_RS18050	COG4133	protoheme IX ABC transporter activity
PotMrB4_RS18060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PotMrB4_RS18075	COG0835	chemotaxis
PotMrB4_RS18085	COG1192	Involved in chromosome partitioning
PotMrB4_RS18090	COG1360	Flagellar Motor Protein
PotMrB4_RS18095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PotMrB4_RS18100	COG2201	protein-glutamate methylesterase activity
PotMrB4_RS18105	COG0643	Histidine kinase
PotMrB4_RS18105	COG0784	Response regulator, receiver
PotMrB4_RS18105	COG2198	Histidine kinase
PotMrB4_RS18110	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PotMrB4_RS18140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PotMrB4_RS18190	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS18200	COG2882	bacterial-type flagellum organization
PotMrB4_RS18235	COG3852	Histidine kinase
PotMrB4_RS18270	COG0438	transferase activity, transferring glycosyl groups
PotMrB4_RS18270	COG1216	Glycosyl transferase, family 2
PotMrB4_RS18285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PotMrB4_RS18295	COG0107	imidazoleglycerol-phosphate synthase activity
PotMrB4_RS18300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PotMrB4_RS18305	COG2089	acid synthase
PotMrB4_RS18320	COG1083	cytidylyl-transferase
PotMrB4_RS18335	COG1086	Polysaccharide biosynthesis protein
PotMrB4_RS18345	COG1256	bacterial-type flagellum assembly
PotMrB4_RS18355	COG1706	bacterial-type flagellum-dependent cell motility
PotMrB4_RS18365	COG4786	Flagellar basal body rod
PotMrB4_RS18370	COG4787	bacterial-type flagellum-dependent cell motility
PotMrB4_RS18375	COG1749	Flagellar hook protein flgE
PotMrB4_RS18390	COG1815	bacterial-type flagellum-dependent cell motility
PotMrB4_RS18395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PotMrB4_RS18400	COG0784	Response regulator, receiver
PotMrB4_RS18400	COG0835	chemotaxis
PotMrB4_RS18405	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
PotMrB4_RS18420	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PotMrB4_RS18425	COG0477	Major facilitator Superfamily
PotMrB4_RS18440	COG0730	response to heat
PotMrB4_RS18445	COG2816	NAD+ diphosphatase activity
PotMrB4_RS18455	COG1024	Enoyl-CoA hydratase
PotMrB4_RS18460	COG0531	amino acid
PotMrB4_RS18465	COG1982	Orn Lys Arg decarboxylase major
PotMrB4_RS18475	COG0328	RNA-DNA hybrid ribonuclease activity
PotMrB4_RS18490	COG0741	lytic transglycosylase activity
PotMrB4_RS18490	COG1388	LysM domain
PotMrB4_RS18500	COG4166	transmembrane transport
PotMrB4_RS18505	COG4166	transmembrane transport
PotMrB4_RS18510	COG4174	ABC transporter (Permease)
PotMrB4_RS18515	COG4239	(ABC) transporter, permease
PotMrB4_RS18520	COG4172	Belongs to the ABC transporter superfamily
PotMrB4_RS18530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PotMrB4_RS18540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PotMrB4_RS18555	COG0544	peptidyl-prolyl cis-trans isomerase activity
PotMrB4_RS18605	COG4771	TonB-dependent receptor
PotMrB4_RS18615	COG1032	radical SAM domain protein
PotMrB4_RS18630	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS18635	COG0583	DNA-binding transcription factor activity
PotMrB4_RS18640	COG0583	DNA-binding transcription factor activity
PotMrB4_RS18645	COG0504	CTP synthase activity
PotMrB4_RS18650	COG2329	Antibiotic biosynthesis monooxygenase
PotMrB4_RS18660	COG0840	transmembrane signaling receptor activity
PotMrB4_RS18695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PotMrB4_RS18700	COG0431	NADPH-dependent FMN reductase
PotMrB4_RS18710	COG3829	transcription factor binding
PotMrB4_RS18715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PotMrB4_RS18745	COG1335	isochorismatase
PotMrB4_RS18755	COG0583	DNA-binding transcription factor activity
PotMrB4_RS18765	COG0024	Methionine aminopeptidase
PotMrB4_RS18775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PotMrB4_RS18790	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS18810	COG0616	signal peptide processing
PotMrB4_RS18815	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PotMrB4_RS18820	COG0583	DNA-binding transcription factor activity
PotMrB4_RS18845	COG4991	sh3 domain protein
PotMrB4_RS18850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PotMrB4_RS18855	COG1045	serine acetyltransferase
PotMrB4_RS18860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PotMrB4_RS18875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS18885	COG0121	glutamine amidotransferase
PotMrB4_RS18900	COG1770	oligopeptidase
PotMrB4_RS18915	COG4807	Protein conserved in bacteria
PotMrB4_RS18925	COG1629	transport
PotMrB4_RS18935	COG1595	DNA-templated transcription, initiation
PotMrB4_RS18960	COG0308	aminopeptidase N
PotMrB4_RS18980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PotMrB4_RS18985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PotMrB4_RS18995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PotMrB4_RS19015	COG1902	pentaerythritol trinitrate reductase activity
PotMrB4_RS19015	COG0446	pyridine nucleotide-disulphide oxidoreductase
PotMrB4_RS19115	COG1286	toxin biosynthetic process
PotMrB4_RS19125	COG0285	dihydrofolate synthase activity
PotMrB4_RS19130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PotMrB4_RS19135	COG0135	phosphoribosylanthranilate isomerase activity
PotMrB4_RS19165	COG2226	methyltransferase
PotMrB4_RS19170	COG0066	3-isopropylmalate dehydratase activity
PotMrB4_RS19175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PotMrB4_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS19215	COG0800	Aldolase
PotMrB4_RS19245	COG0583	DNA-binding transcription factor activity
PotMrB4_RS19305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PotMrB4_RS19320	COG1045	serine acetyltransferase
PotMrB4_RS19335	COG1215	transferase activity, transferring glycosyl groups
PotMrB4_RS19375	COG0776	regulation of translation
PotMrB4_RS19385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PotMrB4_RS19390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PotMrB4_RS19405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PotMrB4_RS19415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PotMrB4_RS19420	COG0402	S-adenosylhomocysteine deaminase activity
PotMrB4_RS19425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PotMrB4_RS19430	COG0546	phosphoglycolate phosphatase activity
PotMrB4_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS19440	COG3706	GGDEF domain
PotMrB4_RS19455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PotMrB4_RS19460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PotMrB4_RS19465	COG0009	L-threonylcarbamoyladenylate synthase
PotMrB4_RS19475	COG2917	probably involved in intracellular septation
PotMrB4_RS19480	COG2350	Protein conserved in bacteria
PotMrB4_RS19490	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS19505	COG0778	Nitroreductase
PotMrB4_RS19510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PotMrB4_RS19515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PotMrB4_RS19545	COG0297	glycogen (starch) synthase activity
PotMrB4_RS19555	COG2207	Transcriptional regulator
PotMrB4_RS19560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PotMrB4_RS19560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PotMrB4_RS19580	COG1752	Esterase of the alpha-beta hydrolase superfamily
PotMrB4_RS19590	COG2814	Major facilitator Superfamily
PotMrB4_RS19605	COG2203	Gaf domain
PotMrB4_RS19605	COG3706	GGDEF domain
PotMrB4_RS19605	COG4251	negative regulation of phosphorylation
PotMrB4_RS19605	COG5001	Diguanylate cyclase
PotMrB4_RS19610	COG0514	ATP-dependent DNA helicase (RecQ)
PotMrB4_RS19620	COG2832	Protein of unknown function (DUF454)
PotMrB4_RS19630	COG2199	diguanylate cyclase activity
PotMrB4_RS19630	COG2200	EAL domain
PotMrB4_RS19650	COG4772	TonB-dependent receptor
PotMrB4_RS19655	COG2188	Transcriptional regulator
PotMrB4_RS19680	COG3842	ATPase activity
PotMrB4_RS19705	COG2814	Major facilitator Superfamily
PotMrB4_RS19710	COG1566	PFAM secretion protein HlyD family protein
PotMrB4_RS19720	COG1846	Transcriptional regulator
PotMrB4_RS19735	COG1309	transcriptional regulator
PotMrB4_RS19770	COG1846	Transcriptional regulator
PotMrB4_RS19785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS19795	COG2909	trisaccharide binding
PotMrB4_RS19820	COG3501	Rhs element vgr protein
PotMrB4_RS19835	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS19880	COG0531	amino acid
PotMrB4_RS19910	COG2801	Transposase and inactivated derivatives
PotMrB4_RS19910	COG3415	Transposase
PotMrB4_RS19915	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS19940	COG1477	protein flavinylation
PotMrB4_RS19950	COG0288	reversible hydration of carbon dioxide
PotMrB4_RS19955	COG0714	Associated with various cellular activities
PotMrB4_RS19975	COG2304	oxidoreductase activity
PotMrB4_RS19995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PotMrB4_RS20010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PotMrB4_RS20015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS20060	COG0527	aspartate kinase activity
PotMrB4_RS20065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PotMrB4_RS20070	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PotMrB4_RS20075	COG2988	succinylglutamate desuccinylase activity
PotMrB4_RS20155	COG1764	response to oxidative stress
PotMrB4_RS20165	COG1742	UPF0060 membrane protein
PotMrB4_RS20195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PotMrB4_RS20200	COG3162	membrane
PotMrB4_RS20245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PotMrB4_RS20255	COG0084	hydrolase, TatD family'
PotMrB4_RS20275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PotMrB4_RS20285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PotMrB4_RS20290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PotMrB4_RS20305	COG0416	fatty acid biosynthetic process
PotMrB4_RS20310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PotMrB4_RS20320	COG0424	maF-like protein
PotMrB4_RS20325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PotMrB4_RS20325	COG0616	signal peptide processing
PotMrB4_RS20330	COG0546	phosphoglycolate phosphatase activity
PotMrB4_RS20340	COG1530	ribonuclease E activity
PotMrB4_RS20385	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS20400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PotMrB4_RS20405	COG0406	alpha-ribazole phosphatase activity
PotMrB4_RS20420	COG1492	cobalamin metabolic process
PotMrB4_RS20430	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PotMrB4_RS20435	COG0778	Nitroreductase
PotMrB4_RS20450	COG4206	TonB-dependent receptor
PotMrB4_RS20460	COG2205	protein histidine kinase activity
PotMrB4_RS20465	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS20475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PotMrB4_RS20485	COG0697	spore germination
PotMrB4_RS20495	COG0183	Belongs to the thiolase family
PotMrB4_RS20520	COG2853	Lipoprotein
PotMrB4_RS20535	COG1560	Kdo2-lipid A biosynthetic process
PotMrB4_RS20540	COG0850	regulation of cytokinetic process
PotMrB4_RS20545	COG2894	cell division
PotMrB4_RS20550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PotMrB4_RS20555	COG0564	pseudouridine synthase activity
PotMrB4_RS20565	COG1362	aminopeptidase activity
PotMrB4_RS20570	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PotMrB4_RS20590	COG0791	NLP P60 protein
PotMrB4_RS20595	COG0791	NLP P60 protein
PotMrB4_RS20630	COG3091	SprT-like family
PotMrB4_RS20650	COG2274	protein secretion by the type I secretion system
PotMrB4_RS20655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS20660	COG0784	Response regulator, receiver
PotMrB4_RS20660	COG2205	protein histidine kinase activity
PotMrB4_RS20685	COG0582	viral genome integration into host DNA
PotMrB4_RS20805	COG1522	sequence-specific DNA binding
PotMrB4_RS20825	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PotMrB4_RS20835	COG2239	Acts as a magnesium transporter
PotMrB4_RS20855	COG3179	chitinase
PotMrB4_RS21065	COG0656	L-ascorbic acid biosynthetic process
PotMrB4_RS21110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PotMrB4_RS21155	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS21165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PotMrB4_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS21175	COG0604	alcohol dehydrogenase
PotMrB4_RS21175	COG3321	synthase
PotMrB4_RS21215	COG3609	addiction module antidote protein, CC2985 family
PotMrB4_RS21230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PotMrB4_RS21235	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PotMrB4_RS21240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PotMrB4_RS21250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PotMrB4_RS21260	COG0425	Belongs to the sulfur carrier protein TusA family
PotMrB4_RS21265	COG4783	chaperone-mediated protein folding
PotMrB4_RS21285	COG0602	queuosine metabolic process
PotMrB4_RS21290	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PotMrB4_RS21295	COG2885	chlorophyll binding
PotMrB4_RS21320	COG0824	Thioesterase
PotMrB4_RS21325	COG2255	four-way junction helicase activity
PotMrB4_RS21335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PotMrB4_RS21345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PotMrB4_RS21355	COG0783	Belongs to the Dps family
PotMrB4_RS21370	COG2900	Belongs to the SlyX family
PotMrB4_RS21445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PotMrB4_RS21450	COG0628	permease
PotMrB4_RS21460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PotMrB4_RS21465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PotMrB4_RS21480	COG3122	Protein conserved in bacteria
PotMrB4_RS21485	COG3956	TIGRFAM MazG family protein
PotMrB4_RS21490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PotMrB4_RS21525	COG0500	methyltransferase
PotMrB4_RS21545	COG0784	Response regulator, receiver
PotMrB4_RS21545	COG5002	protein histidine kinase activity
PotMrB4_RS21545	COG2205	protein histidine kinase activity
PotMrB4_RS21550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PotMrB4_RS21565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PotMrB4_RS21580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PotMrB4_RS21580	COG0392	lysyltransferase activity
PotMrB4_RS21590	COG3038	cytochrome b561
PotMrB4_RS21600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PotMrB4_RS21635	COG0583	DNA-binding transcription factor activity
PotMrB4_RS21685	COG1546	Belongs to the CinA family
PotMrB4_RS21710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PotMrB4_RS21715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PotMrB4_RS21720	COG0585	pseudouridine synthase activity
PotMrB4_RS21725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PotMrB4_RS21730	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PotMrB4_RS21735	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PotMrB4_RS21760	COG0148	phosphopyruvate hydratase activity
PotMrB4_RS21765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PotMrB4_RS21770	COG0504	CTP synthase activity
PotMrB4_RS21780	COG0825	malonyl-CoA metabolic process
PotMrB4_RS21790	COG1115	amino acid carrier protein
PotMrB4_RS21795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PotMrB4_RS21805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PotMrB4_RS21810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PotMrB4_RS21825	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PotMrB4_RS21835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PotMrB4_RS21845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PotMrB4_RS21850	COG0233	cytoplasmic translational termination
PotMrB4_RS21865	COG0052	Belongs to the universal ribosomal protein uS2 family
PotMrB4_RS21870	COG0024	Methionine aminopeptidase
PotMrB4_RS21875	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PotMrB4_RS21880	COG0436	Aminotransferase
PotMrB4_RS21895	COG1393	Belongs to the ArsC family
PotMrB4_RS21900	COG2171	N-acyltransferase activity
PotMrB4_RS21915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PotMrB4_RS21920	COG1979	alcohol dehydrogenase
PotMrB4_RS21925	COG1215	transferase activity, transferring glycosyl groups
PotMrB4_RS21935	COG2226	methyltransferase
PotMrB4_RS21955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PotMrB4_RS21960	COG0243	molybdopterin cofactor binding
PotMrB4_RS21975	COG3842	ATPase activity
PotMrB4_RS21985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PotMrB4_RS21990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PotMrB4_RS22010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PotMrB4_RS22025	COG0583	DNA-binding transcription factor activity
PotMrB4_RS22030	COG0583	DNA-binding transcription factor activity
PotMrB4_RS22040	COG0183	Belongs to the thiolase family
PotMrB4_RS22045	COG1250	3-hydroxyacyl-CoA dehydrogenase
PotMrB4_RS22050	COG1024	Enoyl-CoA hydratase
PotMrB4_RS22055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PotMrB4_RS22060	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS22065	COG0583	DNA-binding transcription factor activity
PotMrB4_RS22070	COG0477	Major facilitator Superfamily
PotMrB4_RS22075	COG0531	amino acid
PotMrB4_RS22090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS22095	COG0174	glutamine synthetase
PotMrB4_RS22130	COG4974	Belongs to the 'phage' integrase family
PotMrB4_RS22140	COG4128	Pfam Zonular occludens toxin
PotMrB4_RS22215	COG0326	Molecular chaperone. Has ATPase activity
PotMrB4_RS22225	COG0270	DNA (cytosine-5-)-methyltransferase activity
PotMrB4_RS22230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PotMrB4_RS22280	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS22285	COG5002	protein histidine kinase activity
PotMrB4_RS22285	COG5000	phosphorelay sensor kinase activity
PotMrB4_RS22315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PotMrB4_RS22360	COG0789	Transcriptional regulator
PotMrB4_RS22380	COG0784	Response regulator, receiver
PotMrB4_RS22385	COG4251	negative regulation of phosphorylation
PotMrB4_RS22395	COG0579	oxidoreductase
PotMrB4_RS22410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PotMrB4_RS22440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PotMrB4_RS22455	COG5001	Diguanylate cyclase
PotMrB4_RS22455	COG5002	protein histidine kinase activity
PotMrB4_RS22455	COG3447	MASE1 domain protein
PotMrB4_RS22460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PotMrB4_RS22485	COG1842	Phage shock protein A
PotMrB4_RS22490	COG3789	protein conserved in bacteria
PotMrB4_RS22495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PotMrB4_RS22555	COG1607	acyl-coa hydrolase
PotMrB4_RS22560	COG2205	protein histidine kinase activity
PotMrB4_RS22560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS22565	COG0335	large ribosomal subunit rRNA binding
PotMrB4_RS22570	COG0336	Belongs to the RNA methyltransferase TrmD family
PotMrB4_RS22575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PotMrB4_RS22580	COG0228	four-way junction DNA binding
PotMrB4_RS22585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PotMrB4_RS22595	COG4536	flavin adenine dinucleotide binding
PotMrB4_RS22600	COG0477	Major facilitator Superfamily
PotMrB4_RS22625	COG0494	nUDIX hydrolase
PotMrB4_RS22635	COG3034	peptidoglycan biosynthetic process
PotMrB4_RS22655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PotMrB4_RS22665	COG0590	tRNA wobble adenosine to inosine editing
PotMrB4_RS22675	COG1178	ABC-type Fe3 transport system permease component
PotMrB4_RS22680	COG1840	ABC-type Fe3 transport system, periplasmic component
PotMrB4_RS22700	COG0583	DNA-binding transcription factor activity
PotMrB4_RS22710	COG1570	exodeoxyribonuclease VII activity
PotMrB4_RS22715	COG0739	heme binding
PotMrB4_RS22720	COG0668	transmembrane transport
PotMrB4_RS22725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PotMrB4_RS22740	COG1733	regulation of RNA biosynthetic process
PotMrB4_RS22750	COG0436	Aminotransferase
PotMrB4_RS22755	COG1160	GTP binding
PotMrB4_RS22765	COG2976	Protein conserved in bacteria
PotMrB4_RS22795	COG0105	UTP biosynthetic process
PotMrB4_RS22820	COG0316	Belongs to the HesB IscA family
PotMrB4_RS22830	COG1104	cysteine desulfurase activity
PotMrB4_RS22855	COG3134	Outer membrane lipoprotein
PotMrB4_RS22870	COG1862	Preprotein translocase
PotMrB4_RS22880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PotMrB4_RS22890	COG1278	Cold shock
PotMrB4_RS22900	COG0795	lipopolysaccharide-transporting ATPase activity
PotMrB4_RS22905	COG0795	lipopolysaccharide-transporting ATPase activity
PotMrB4_RS22940	COG0154	amidase activity
PotMrB4_RS22950	COG0490	domain, Protein
PotMrB4_RS22950	COG0471	metal ion transport
PotMrB4_RS22965	COG0419	ATPase involved in DNA repair
PotMrB4_RS22970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS22975	COG0420	3'-5' exonuclease activity
PotMrB4_RS22995	COG3081	Nucleoid-associated protein
PotMrB4_RS23000	COG1595	DNA-templated transcription, initiation
PotMrB4_RS23040	COG1126	abc transporter atp-binding protein
PotMrB4_RS23045	COG0765	amino acid transport
PotMrB4_RS23050	COG4597	amino acid ABC transporter
PotMrB4_RS23055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PotMrB4_RS23060	COG0400	carboxylic ester hydrolase activity
PotMrB4_RS23065	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS23070	COG3706	GGDEF domain
PotMrB4_RS23120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PotMrB4_RS23125	COG0315	cyclic pyranopterin monophosphate synthase activity
PotMrB4_RS23130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PotMrB4_RS23165	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PotMrB4_RS23215	COG0300	oxidoreductase activity
PotMrB4_RS23245	COG0697	spore germination
PotMrB4_RS23250	COG2207	Transcriptional regulator
PotMrB4_RS23255	COG1595	DNA-templated transcription, initiation
PotMrB4_RS23260	COG3712	iron ion homeostasis
PotMrB4_RS23285	COG4774	siderophore transport
PotMrB4_RS23290	COG3712	iron ion homeostasis
PotMrB4_RS23295	COG1595	DNA-templated transcription, initiation
PotMrB4_RS23340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PotMrB4_RS23355	COG2197	response regulator
PotMrB4_RS23385	COG2207	Transcriptional regulator
PotMrB4_RS23390	COG1073	alpha beta
PotMrB4_RS23400	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS23425	COG1346	cytolysis
PotMrB4_RS23435	COG0583	DNA-binding transcription factor activity
PotMrB4_RS23450	COG1366	Belongs to the anti-sigma-factor antagonist family
PotMrB4_RS23475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PotMrB4_RS23495	COG0492	ferredoxin-NADP+ reductase activity
PotMrB4_RS23510	COG1307	EDD domain protein, DegV family
PotMrB4_RS23520	COG1309	transcriptional regulator
PotMrB4_RS23525	COG0386	Belongs to the glutathione peroxidase family
PotMrB4_RS23550	COG0204	Acyl-transferase
PotMrB4_RS23575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PotMrB4_RS23590	COG2267	carboxylic ester hydrolase activity
PotMrB4_RS23620	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS23625	COG0183	Belongs to the thiolase family
PotMrB4_RS23640	COG1280	lysine exporter protein (LysE YggA)
PotMrB4_RS23645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PotMrB4_RS23650	COG2813	Specifically methylates the guanine in position
PotMrB4_RS23655	COG0833	amino acid
PotMrB4_RS23660	COG2119	membrane
PotMrB4_RS23670	COG0501	Belongs to the peptidase M48B family
PotMrB4_RS23675	COG0840	transmembrane signaling receptor activity
PotMrB4_RS23700	COG2135	peptidase activity
PotMrB4_RS23735	COG0659	secondary active sulfate transmembrane transporter activity
PotMrB4_RS23750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PotMrB4_RS23760	COG2271	Major facilitator Superfamily
PotMrB4_RS23765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PotMrB4_RS23770	COG1090	epimerase
PotMrB4_RS23775	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PotMrB4_RS23785	COG0789	Transcriptional regulator
PotMrB4_RS23800	COG4221	oxidoreductase activity
PotMrB4_RS23815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PotMrB4_RS23830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PotMrB4_RS23835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PotMrB4_RS23850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PotMrB4_RS23860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PotMrB4_RS23865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PotMrB4_RS23885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PotMrB4_RS23905	COG0789	Transcriptional regulator
PotMrB4_RS23910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PotMrB4_RS23915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PotMrB4_RS23920	COG0803	Belongs to the bacterial solute-binding protein 9 family
PotMrB4_RS23930	COG1116	anion transmembrane transporter activity
PotMrB4_RS23995	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS24000	COG1113	amino acid transport
PotMrB4_RS24010	COG0288	reversible hydration of carbon dioxide
PotMrB4_RS24015	COG0456	acetyltransferase
PotMrB4_RS24025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PotMrB4_RS24075	COG3008	intermembrane lipid transfer
PotMrB4_RS24080	COG2995	paraquat-inducible protein a
PotMrB4_RS24085	COG2995	paraquat-inducible protein a
PotMrB4_RS24120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PotMrB4_RS24125	COG1183	phosphatidylcholine synthase activity
PotMrB4_RS24135	COG0583	DNA-binding transcription factor activity
PotMrB4_RS24145	COG0028	Belongs to the TPP enzyme family
PotMrB4_RS24155	COG3098	single-species biofilm formation
PotMrB4_RS24165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PotMrB4_RS24190	COG0813	purine-nucleoside phosphorylase activity
PotMrB4_RS24195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PotMrB4_RS24210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PotMrB4_RS24215	COG4558	Periplasmic binding protein
PotMrB4_RS24220	COG3720	iron ion transport
PotMrB4_RS24235	COG0436	Aminotransferase
PotMrB4_RS24240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PotMrB4_RS24245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PotMrB4_RS24255	COG4191	Histidine kinase
PotMrB4_RS24275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PotMrB4_RS24365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PotMrB4_RS24385	COG0195	Participates in both transcription termination and antitermination
PotMrB4_RS24390	COG0779	Required for maturation of 30S ribosomal subunits
PotMrB4_RS24405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PotMrB4_RS24415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PotMrB4_RS24420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PotMrB4_RS24475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PotMrB4_RS24480	COG0497	DNA recombination
PotMrB4_RS24490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PotMrB4_RS24505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PotMrB4_RS24510	COG2186	Transcriptional regulator
PotMrB4_RS24515	COG1620	l-lactate permease
PotMrB4_RS24535	COG2205	protein histidine kinase activity
PotMrB4_RS24610	COG2226	methyltransferase
PotMrB4_RS24615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PotMrB4_RS24620	COG0697	spore germination
PotMrB4_RS24640	COG3268	Saccharopine dehydrogenase
PotMrB4_RS24645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PotMrB4_RS24650	COG0066	3-isopropylmalate dehydratase activity
PotMrB4_RS24655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PotMrB4_RS24660	COG0583	DNA-binding transcription factor activity
PotMrB4_RS24665	COG3493	citrate carrier protein
PotMrB4_RS24670	COG3706	GGDEF domain
PotMrB4_RS24675	COG0640	Transcriptional regulator
PotMrB4_RS24680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PotMrB4_RS24685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PotMrB4_RS24710	COG1113	amino acid transport
PotMrB4_RS24720	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS24740	COG1309	transcriptional regulator
PotMrB4_RS24750	COG0583	DNA-binding transcription factor activity
PotMrB4_RS24775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PotMrB4_RS24790	COG2072	flavoprotein involved in K transport
PotMrB4_RS24815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PotMrB4_RS24835	COG1294	oxidase, subunit
PotMrB4_RS24840	COG4890	Cyd operon protein YbgT
PotMrB4_RS24875	COG0583	DNA-binding transcription factor activity
PotMrB4_RS24880	COG1309	transcriptional regulator
PotMrB4_RS24945	COG1943	Transposase
PotMrB4_RS24995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PotMrB4_RS25000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PotMrB4_RS25005	COG0477	Major facilitator Superfamily
PotMrB4_RS25020	COG5001	Diguanylate cyclase
PotMrB4_RS25020	COG5002	protein histidine kinase activity
PotMrB4_RS25020	COG3447	MASE1 domain protein
PotMrB4_RS25025	COG0583	DNA-binding transcription factor activity
PotMrB4_RS25030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PotMrB4_RS25045	COG2814	Major facilitator Superfamily
PotMrB4_RS25085	COG2217	Heavy metal translocating P-type atpase
PotMrB4_RS25115	COG2910	NAD(P)H-binding
PotMrB4_RS25125	COG3152	Membrane
PotMrB4_RS25140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PotMrB4_RS25145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PotMrB4_RS25155	COG1238	metal cluster binding
PotMrB4_RS25165	COG0443	Heat shock 70 kDa protein
PotMrB4_RS25180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PotMrB4_RS25185	COG2193	ferroxidase activity
PotMrB4_RS25195	COG2982	Protein involved in outer membrane biogenesis
PotMrB4_RS25230	COG0830	nickel cation binding
PotMrB4_RS25235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PotMrB4_RS25245	COG0584	glycerophosphoryl diester phosphodiesterase
PotMrB4_RS25250	COG4221	oxidoreductase activity
PotMrB4_RS25255	COG2423	ornithine cyclodeaminase activity
PotMrB4_RS25280	COG0683	leucine binding
PotMrB4_RS25285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS25290	COG1012	belongs to the aldehyde dehydrogenase family
PotMrB4_RS25295	COG0583	DNA-binding transcription factor activity
PotMrB4_RS25345	COG1305	Transglutaminase-like
PotMrB4_RS25365	COG0305	Participates in initiation and elongation during chromosome replication
PotMrB4_RS25370	COG0359	binds to the 23S rRNA
PotMrB4_RS25380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PotMrB4_RS25385	COG0360	Binds together with S18 to 16S ribosomal RNA
PotMrB4_RS25395	COG0557	exoribonuclease II activity
PotMrB4_RS25420	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PotMrB4_RS25430	COG0330	HflC and HflK could
PotMrB4_RS25435	COG0330	HflC and HflK could
PotMrB4_RS25440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PotMrB4_RS25445	COG1923	regulation of RNA biosynthetic process
PotMrB4_RS25450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PotMrB4_RS25455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PotMrB4_RS25460	COG0860	N-Acetylmuramoyl-L-alanine amidase
PotMrB4_RS25465	COG0802	atpase or kinase
PotMrB4_RS25470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PotMrB4_RS25470	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PotMrB4_RS25480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PotMrB4_RS25485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PotMrB4_RS25490	COG1162	GTPase activity
PotMrB4_RS25495	COG1360	Flagellar Motor Protein
PotMrB4_RS25500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PotMrB4_RS25515	COG0688	phosphatidylethanolamine metabolic process
PotMrB4_RS25530	COG3830	Belongs to the UPF0237 family
PotMrB4_RS25530	COG0560	Phosphoserine phosphatase
PotMrB4_RS25540	COG1988	membrane-bound metal-dependent
PotMrB4_RS25555	COG3577	Aspartyl protease
PotMrB4_RS25570	COG3150	esterase
PotMrB4_RS25575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PotMrB4_RS25585	COG0494	nUDIX hydrolase
PotMrB4_RS25600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PotMrB4_RS25605	COG1538	Outer membrane efflux protein
PotMrB4_RS25610	COG2249	NAD(P)H dehydrogenase (quinone) activity
PotMrB4_RS25630	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS25635	COG1024	Enoyl-CoA hydratase
PotMrB4_RS25645	COG0833	amino acid
PotMrB4_RS25670	COG1396	sequence-specific DNA binding
PotMrB4_RS25675	COG0235	Class ii aldolase
PotMrB4_RS25680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PotMrB4_RS25685	COG0235	Class ii aldolase
PotMrB4_RS25695	COG0446	pyridine nucleotide-disulphide oxidoreductase
PotMrB4_RS25695	COG1902	pentaerythritol trinitrate reductase activity
PotMrB4_RS25705	COG1519	Transferase
PotMrB4_RS25710	COG0583	DNA-binding transcription factor activity
PotMrB4_RS25725	COG0656	L-ascorbic acid biosynthetic process
PotMrB4_RS25735	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS25745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PotMrB4_RS25745	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PotMrB4_RS25760	COG1132	(ABC) transporter
PotMrB4_RS25775	COG1215	transferase activity, transferring glycosyl groups
PotMrB4_RS25795	COG0438	transferase activity, transferring glycosyl groups
PotMrB4_RS25800	COG2192	nodulation
PotMrB4_RS25825	COG0438	transferase activity, transferring glycosyl groups
PotMrB4_RS25835	COG0859	PFAM glycosyl transferase family 9
PotMrB4_RS25870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PotMrB4_RS25875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PotMrB4_RS25880	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS25920	COG3263	regulation of cellular component size
PotMrB4_RS25925	COG3264	Mechanosensitive ion channel
PotMrB4_RS25925	COG1196	nuclear chromosome segregation
PotMrB4_RS25930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PotMrB4_RS25935	COG1794	racemase activity, acting on amino acids and derivatives
PotMrB4_RS25940	COG0730	response to heat
PotMrB4_RS25945	COG2873	o-acetylhomoserine
PotMrB4_RS25950	COG3118	belongs to the thioredoxin family
PotMrB4_RS25970	COG1192	Involved in chromosome partitioning
PotMrB4_RS25990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PotMrB4_RS26015	COG2986	histidine ammonia-lyase
PotMrB4_RS26065	COG1028	Short-chain dehydrogenase reductase Sdr
PotMrB4_RS26070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PotMrB4_RS26095	COG0493	'glutamate synthase
PotMrB4_RS26100	COG0067	glutamate synthase
PotMrB4_RS26100	COG0069	glutamate synthase activity
PotMrB4_RS26100	COG0070	glutamate synthase
PotMrB4_RS26110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PotMrB4_RS26115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PotMrB4_RS26140	COG0443	Heat shock 70 kDa protein
PotMrB4_RS26150	COG0281	malic enzyme
PotMrB4_RS26160	COG0254	rRNA binding
PotMrB4_RS26165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PotMrB4_RS26170	COG0018	arginyl-trna synthetase
PotMrB4_RS26185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PotMrB4_RS26210	COG1309	transcriptional regulator
PotMrB4_RS26250	COG0140	phosphoribosyl-ATP diphosphatase activity
PotMrB4_RS26275	COG0840	transmembrane signaling receptor activity
PotMrB4_RS26280	COG0840	transmembrane signaling receptor activity
PotMrB4_RS26300	COG0765	amino acid transport
PotMrB4_RS26310	COG1490	D-aminoacyl-tRNA deacylase activity
PotMrB4_RS26315	COG0596	Alpha beta hydrolase
PotMrB4_RS26365	COG0402	S-adenosylhomocysteine deaminase activity
PotMrB4_RS26385	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PotMrB4_RS26390	COG3706	GGDEF domain
PotMrB4_RS26410	COG2354	Protein conserved in bacteria
PotMrB4_RS26415	COG2194	sulfuric ester hydrolase activity
PotMrB4_RS26430	COG2860	membrane
PotMrB4_RS26445	COG0301	tRNA thio-modification
PotMrB4_RS26445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PotMrB4_RS26465	COG3852	Histidine kinase
PotMrB4_RS26480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PotMrB4_RS26485	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PotMrB4_RS26495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PotMrB4_RS26500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PotMrB4_RS26505	COG4942	peptidase
PotMrB4_RS26510	COG0793	Belongs to the peptidase S41A family
PotMrB4_RS26515	COG2861	carbohydrate metabolic process
PotMrB4_RS26545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PotMrB4_RS26560	COG0131	Imidazoleglycerol-phosphate dehydratase
PotMrB4_RS26565	COG2223	nitrite transmembrane transporter activity
PotMrB4_RS26585	COG1194	a g-specific adenine glycosylase
PotMrB4_RS26605	COG0318	PFAM AMP-dependent synthetase and ligase
PotMrB4_RS26625	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS26630	COG0642	Histidine kinase
PotMrB4_RS26635	COG0784	Response regulator, receiver
PotMrB4_RS26635	COG2205	protein histidine kinase activity
PotMrB4_RS26645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PotMrB4_RS26650	COG0784	Response regulator, receiver
PotMrB4_RS26650	COG2198	Histidine kinase
PotMrB4_RS26650	COG2205	protein histidine kinase activity
PotMrB4_RS26670	COG4215	(ABC) transporter
PotMrB4_RS26755	COG0494	nUDIX hydrolase
PotMrB4_RS26760	COG1011	Hydrolase
PotMrB4_RS26765	COG0583	DNA-binding transcription factor activity
PotMrB4_RS26770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PotMrB4_RS26800	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PotMrB4_RS26810	COG1454	alcohol dehydrogenase
PotMrB4_RS26815	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS26820	COG1250	3-hydroxyacyl-CoA dehydrogenase
PotMrB4_RS26820	COG1024	Enoyl-CoA hydratase
PotMrB4_RS26855	COG2183	response to ionizing radiation
PotMrB4_RS26860	COG0745	RESPONSE REGULATOR receiver
PotMrB4_RS26865	COG2205	protein histidine kinase activity
PotMrB4_RS26875	COG0189	ligase activity
PotMrB4_RS26880	COG4067	protein conserved in archaea
PotMrB4_RS26880	COG0189	ligase activity
PotMrB4_RS26885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PotMrB4_RS26890	COG0671	phosphoesterase, PA-phosphatase related
PotMrB4_RS26905	COG0514	ATP-dependent DNA helicase (RecQ)
PotMrB4_RS26910	COG0778	Nitroreductase
PotMrB4_RS26915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PotMrB4_RS26915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PotMrB4_RS26925	COG3025	triphosphatase activity
PotMrB4_RS26935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PotMrB4_RS26940	COG1522	sequence-specific DNA binding
PotMrB4_RS26955	COG0330	HflC and HflK could
PotMrB4_RS26975	COG2957	Belongs to the agmatine deiminase family
PotMrB4_RS26990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PotMrB4_RS26995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PotMrB4_RS27000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS27005	COG0431	NADPH-dependent FMN reductase
PotMrB4_RS27010	COG0450	alkyl hydroperoxide reductase
PotMrB4_RS27020	COG4521	taurine ABC transporter
PotMrB4_RS27025	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PotMrB4_RS27030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PotMrB4_RS27035	COG2175	clavaminate synthase activity
PotMrB4_RS27045	COG0626	cystathionine gamma-synthase activity
PotMrB4_RS27055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PotMrB4_RS27075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS27080	COG0667	Aldo Keto reductase
PotMrB4_RS27085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PotMrB4_RS27095	COG1609	Transcriptional regulator
PotMrB4_RS27100	COG2814	Major facilitator Superfamily
PotMrB4_RS27135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PotMrB4_RS27155	COG3052	prosthetic group binding
PotMrB4_RS27160	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PotMrB4_RS27210	COG4771	TonB-dependent receptor
PotMrB4_RS27220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PotMrB4_RS27225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PotMrB4_RS27250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PotMrB4_RS27255	COG0583	DNA-binding transcription factor activity
PotMrB4_RS27280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PotMrB4_RS27290	COG4208	sulfate ABC transporter
PotMrB4_RS27345	COG1309	transcriptional regulator
PotMrB4_RS27350	COG4221	oxidoreductase activity
PotMrB4_RS27360	COG1639	'signal transduction protein
PotMrB4_RS27380	COG3835	regulator
PotMrB4_RS27390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PotMrB4_RS27420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PotMrB4_RS27425	COG1960	acyl-CoA dehydrogenase activity
PotMrB4_RS27430	COG0583	DNA-binding transcription factor activity
PotMrB4_RS27515	COG0210	DNA helicase
PotMrB4_RS27530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PotMrB4_RS27545	COG4774	siderophore transport
PotMrB4_RS27550	COG3712	iron ion homeostasis
PotMrB4_RS27565	COG0583	DNA-binding transcription factor activity
PotMrB4_RS27570	COG0439	Biotin carboxylase
PotMrB4_RS27575	COG5016	pyruvate
PotMrB4_RS27575	COG0511	ligase activity, forming carbon-carbon bonds
PotMrB4_RS27610	COG0583	DNA-binding transcription factor activity
PotMrB4_RS27655	COG1115	amino acid carrier protein
PotMrB4_RS27660	COG0252	asparaginase activity
PotMrB4_RS27665	COG0427	acetyl-CoA hydrolase
PotMrB4_RS27705	COG0679	Auxin Efflux Carrier
PotMrB4_RS27710	COG2851	Citrate transporter
PotMrB4_RS27715	COG0861	Integral membrane protein TerC family
PotMrB4_RS27725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PotMrB4_RS27730	COG1690	Belongs to the RtcB family
PotMrB4_RS27735	COG0739	heme binding
PotMrB4_RS27750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PotMrB4_RS27755	COG0573	inorganic phosphate transmembrane transporter activity
PotMrB4_RS27780	COG1607	acyl-coa hydrolase
PotMrB4_RS27795	COG2153	protein acetylation
PotMrB4_RS27805	COG4651	solute:proton antiporter activity
PotMrB4_RS27805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PotMrB4_RS27815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PotMrB4_RS27820	COG0174	glutamine synthetase
PotMrB4_RS27830	COG1607	acyl-coa hydrolase
PotMrB4_RS27845	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PotMrB4_RS27850	COG3706	GGDEF domain
PotMrB4_RS27870	COG4191	Histidine kinase
PotMrB4_RS27875	COG2204	response regulator
PotMrB4_RS27880	COG0477	Major facilitator Superfamily
PotMrB4_RS27885	COG0523	cobalamin synthesis protein
PotMrB4_RS27910	COG1469	GTP cyclohydrolase I activity
PotMrB4_RS27960	COG0754	glutathionylspermidine amidase activity
PotMrB4_RS27980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PotMrB4_RS27985	COG1349	DNA-binding transcription factor activity
PotMrB4_RS27990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PotMrB4_RS28005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PotMrB4_RS28015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PotMrB4_RS28020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PotMrB4_RS28035	COG3312	ion transport
PotMrB4_RS28040	COG1475	DNA binding
PotMrB4_RS28045	COG1192	Involved in chromosome partitioning
PotMrB4_RS28060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PotMrB4_RS28065	COG0706	membrane insertase activity
PotMrB4_RS28070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PotMrB4_RS28075	COG0594	ribonuclease P activity
PotMrB4_RS28080	COG0230	Belongs to the bacterial ribosomal protein bL34 family