locus-tag	class	description
GGD92_RS00010	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS00015	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS00025	COG0789	Transcriptional regulator
GGD92_RS00035	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS00040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGD92_RS00045	COG3422	double-strand break repair
GGD92_RS00050	COG0708	Exodeoxyribonuclease III
GGD92_RS00060	COG0729	surface antigen
GGD92_RS00065	COG2911	Protein conserved in bacteria
GGD92_RS00070	COG1846	Transcriptional regulator
GGD92_RS00080	COG1566	PFAM secretion protein HlyD family protein
GGD92_RS00085	COG2814	Major facilitator Superfamily
GGD92_RS00090	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGD92_RS00100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GGD92_RS00105	COG0215	cysteine-tRNA ligase activity
GGD92_RS00110	COG2944	sequence-specific DNA binding
GGD92_RS00115	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GGD92_RS00135	COG0713	ATP synthesis coupled electron transport
GGD92_RS00145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GGD92_RS00150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GGD92_RS00155	COG1034	ATP synthesis coupled electron transport
GGD92_RS00170	COG0649	NAD binding
GGD92_RS00170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GGD92_RS00175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GGD92_RS00180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GGD92_RS00195	COG2153	protein acetylation
GGD92_RS00200	COG2850	peptidyl-arginine hydroxylation
GGD92_RS00210	COG2915	High frequency lysogenization protein hflD homolog
GGD92_RS00215	COG0482	sulfurtransferase activity
GGD92_RS00235	COG1278	Cold shock
GGD92_RS00240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GGD92_RS00245	COG0542	response to heat
GGD92_RS00250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GGD92_RS00255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GGD92_RS00260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GGD92_RS00265	COG0492	ferredoxin-NADP+ reductase activity
GGD92_RS00270	COG1674	ftsk spoiiie
GGD92_RS00275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GGD92_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GGD92_RS00285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GGD92_RS00290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GGD92_RS00295	COG1648	precorrin-2 dehydrogenase activity
GGD92_RS00295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGD92_RS00305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGD92_RS00315	COG2168	tRNA wobble position uridine thiolation
GGD92_RS00355	COG4948	Mandelate Racemase Muconate Lactonizing
GGD92_RS00360	COG4829	muconolactone delta-isomerase
GGD92_RS00365	COG3485	protocatechuate 3,4-dioxygenase
GGD92_RS00395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS00405	COG0730	response to heat
GGD92_RS00410	COG4221	oxidoreductase activity
GGD92_RS00420	COG0642	Histidine kinase
GGD92_RS00495	COG4804	nuclease activity
GGD92_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS00530	COG0583	DNA-binding transcription factor activity
GGD92_RS00565	COG2207	Transcriptional regulator
GGD92_RS00570	COG2204	response regulator
GGD92_RS00575	COG2205	protein histidine kinase activity
GGD92_RS00575	COG0784	Response regulator, receiver
GGD92_RS00600	COG2200	EAL domain
GGD92_RS00620	COG0626	cystathionine gamma-synthase activity
GGD92_RS00625	COG0833	amino acid
GGD92_RS00630	COG0583	DNA-binding transcription factor activity
GGD92_RS00670	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS00675	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GGD92_RS00690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGD92_RS00695	COG0583	DNA-binding transcription factor activity
GGD92_RS00700	COG3257	ureidoglycine aminohydrolase activity
GGD92_RS00725	COG2135	peptidase activity
GGD92_RS00815	COG3397	chitin binding
GGD92_RS00820	COG3397	chitin binding
GGD92_RS00825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS00825	COG2205	protein histidine kinase activity
GGD92_RS00830	COG2197	response regulator
GGD92_RS00835	COG1522	sequence-specific DNA binding
GGD92_RS00840	COG0697	spore germination
GGD92_RS00850	COG0583	DNA-binding transcription factor activity
GGD92_RS00855	COG0746	molybdenum cofactor guanylyltransferase activity
GGD92_RS00875	COG5002	protein histidine kinase activity
GGD92_RS00875	COG5001	Diguanylate cyclase
GGD92_RS00875	COG3447	MASE1 domain protein
GGD92_RS00885	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GGD92_RS00910	COG0673	inositol 2-dehydrogenase activity
GGD92_RS00920	COG3609	addiction module antidote protein, CC2985 family
GGD92_RS00925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGD92_RS00940	COG0587	DNA-directed DNA polymerase activity
GGD92_RS00960	COG0784	Response regulator, receiver
GGD92_RS00960	COG4191	Histidine kinase
GGD92_RS01000	COG0583	DNA-binding transcription factor activity
GGD92_RS01015	COG0154	amidase activity
GGD92_RS01060	COG1024	Enoyl-CoA hydratase
GGD92_RS01060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GGD92_RS01075	COG0616	signal peptide processing
GGD92_RS01090	COG1609	Transcriptional regulator
GGD92_RS01110	COG0316	Belongs to the HesB IscA family
GGD92_RS01110	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GGD92_RS01175	COG3961	Belongs to the TPP enzyme family
GGD92_RS01180	COG1231	oxidoreductase activity
GGD92_RS01190	COG0473	3-isopropylmalate dehydrogenase activity
GGD92_RS01235	COG0475	glutathione-regulated potassium exporter activity
GGD92_RS01240	COG0154	amidase activity
GGD92_RS01245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGD92_RS01255	COG4335	DNA alkylation repair
GGD92_RS01265	COG2226	methyltransferase
GGD92_RS01280	COG1113	amino acid transport
GGD92_RS01285	COG2423	ornithine cyclodeaminase activity
GGD92_RS01295	COG1522	sequence-specific DNA binding
GGD92_RS01310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GGD92_RS01325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGD92_RS01330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS01340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGD92_RS01355	COG0583	DNA-binding transcription factor activity
GGD92_RS01365	COG1253	flavin adenine dinucleotide binding
GGD92_RS01370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GGD92_RS01430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGD92_RS01435	COG0784	Response regulator, receiver
GGD92_RS01435	COG4191	Histidine kinase
GGD92_RS01440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGD92_RS01445	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS01450	COG2610	gluconate transmembrane transporter activity
GGD92_RS01460	COG4172	Belongs to the ABC transporter superfamily
GGD92_RS01465	COG4239	(ABC) transporter, permease
GGD92_RS01470	COG4174	ABC transporter (Permease)
GGD92_RS01475	COG4166	transmembrane transport
GGD92_RS01480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGD92_RS01485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGD92_RS01500	COG2197	response regulator
GGD92_RS01505	COG0322	excinuclease ABC activity
GGD92_RS01525	COG0765	amino acid transport
GGD92_RS01540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGD92_RS01545	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGD92_RS01560	COG0726	polysaccharide deacetylase
GGD92_RS01570	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS01580	COG1304	FMN binding
GGD92_RS01585	COG0583	DNA-binding transcription factor activity
GGD92_RS01620	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS01620	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGD92_RS01625	COG0006	proline dipeptidase activity
GGD92_RS01635	COG0765	amino acid transport
GGD92_RS01640	COG0765	amino acid transport
GGD92_RS01660	COG0667	Aldo Keto reductase
GGD92_RS01690	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS01700	COG4948	Mandelate Racemase Muconate Lactonizing
GGD92_RS01765	COG0019	diaminopimelate decarboxylase activity
GGD92_RS01770	COG2072	flavoprotein involved in K transport
GGD92_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS01795	COG1113	amino acid transport
GGD92_RS01845	COG1522	sequence-specific DNA binding
GGD92_RS01865	COG2814	Major facilitator Superfamily
GGD92_RS01875	COG1120	ATPase activity
GGD92_RS01880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGD92_RS01895	COG4774	siderophore transport
GGD92_RS01905	COG1021	2,3-dihydroxybenzoate-AMP ligase
GGD92_RS01910	COG1132	(ABC) transporter
GGD92_RS01910	COG2375	cellular response to nickel ion
GGD92_RS01915	COG1132	(ABC) transporter
GGD92_RS01920	COG3433	isochorismatase activity
GGD92_RS01920	COG2226	methyltransferase
GGD92_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGD92_RS01925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGD92_RS01925	COG2226	methyltransferase
GGD92_RS01925	COG3433	isochorismatase activity
GGD92_RS01960	COG1846	Transcriptional regulator
GGD92_RS01965	COG0604	alcohol dehydrogenase
GGD92_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS01965	COG3321	synthase
GGD92_RS01970	COG2814	Major facilitator Superfamily
GGD92_RS01985	COG1024	Enoyl-CoA hydratase
GGD92_RS01990	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS01995	COG3320	Male sterility
GGD92_RS01995	COG1022	Amp-dependent synthetase and ligase
GGD92_RS02000	COG0183	Belongs to the thiolase family
GGD92_RS02005	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS02030	COG2271	Major facilitator Superfamily
GGD92_RS02065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GGD92_RS02165	COG3179	chitinase
GGD92_RS02195	COG5001	Diguanylate cyclase
GGD92_RS02195	COG4251	negative regulation of phosphorylation
GGD92_RS02195	COG3706	GGDEF domain
GGD92_RS02195	COG2203	Gaf domain
GGD92_RS02235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGD92_RS02260	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGD92_RS02355	COG2080	2 iron, 2 sulfur cluster binding
GGD92_RS02360	COG2207	Transcriptional regulator
GGD92_RS02365	COG1064	alcohol dehydrogenase
GGD92_RS02405	COG0488	(ABC) transporter
GGD92_RS02410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GGD92_RS02435	COG2169	Transcriptional regulator
GGD92_RS02435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GGD92_RS02440	COG3145	DNA-N1-methyladenine dioxygenase activity
GGD92_RS02465	COG2863	cytochrome
GGD92_RS02470	COG3258	Cytochrome c
GGD92_RS02530	COG2200	EAL domain
GGD92_RS02535	COG0583	DNA-binding transcription factor activity
GGD92_RS02550	COG1846	Transcriptional regulator
GGD92_RS02560	COG0667	Aldo Keto reductase
GGD92_RS02565	COG0583	DNA-binding transcription factor activity
GGD92_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS02580	COG2271	Major facilitator Superfamily
GGD92_RS02585	COG3835	regulator
GGD92_RS02590	COG1929	Belongs to the glycerate kinase type-1 family
GGD92_RS02600	COG3971	2-oxopent-4-enoate hydratase activity
GGD92_RS02605	COG2271	Major facilitator Superfamily
GGD92_RS02615	COG3384	dioxygenase
GGD92_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS02650	COG1063	alcohol dehydrogenase
GGD92_RS02655	COG2814	Major facilitator Superfamily
GGD92_RS02680	COG2814	Major facilitator Superfamily
GGD92_RS02725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGD92_RS02735	COG1609	Transcriptional regulator
GGD92_RS02765	COG0420	3'-5' exonuclease activity
GGD92_RS02795	COG0714	Associated with various cellular activities
GGD92_RS02960	COG2814	Major facilitator Superfamily
GGD92_RS02980	COG0277	FAD linked oxidase domain protein
GGD92_RS02985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GGD92_RS02990	COG1070	Carbohydrate kinase
GGD92_RS03025	COG0154	amidase activity
GGD92_RS03050	COG1944	ATP diphosphatase activity
GGD92_RS03065	COG2267	carboxylic ester hydrolase activity
GGD92_RS03070	COG4221	oxidoreductase activity
GGD92_RS03075	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS03080	COG1309	transcriptional regulator
GGD92_RS03100	COG2197	response regulator
GGD92_RS03105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGD92_RS03195	COG0811	peptide transport
GGD92_RS03225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGD92_RS03235	COG0456	acetyltransferase
GGD92_RS03240	COG1794	racemase activity, acting on amino acids and derivatives
GGD92_RS03260	COG3278	Belongs to the heme-copper respiratory oxidase family
GGD92_RS03265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGD92_RS03320	COG1538	Outer membrane efflux protein
GGD92_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS03350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS03355	COG0348	domain, Protein
GGD92_RS03375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGD92_RS03380	COG3568	Endonuclease Exonuclease Phosphatase
GGD92_RS03405	COG1640	4-alpha-glucanotransferase
GGD92_RS03410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGD92_RS03415	COG0297	glycogen (starch) synthase activity
GGD92_RS03420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGD92_RS03425	COG1238	metal cluster binding
GGD92_RS03455	COG0667	Aldo Keto reductase
GGD92_RS03460	COG0583	DNA-binding transcription factor activity
GGD92_RS03475	COG2366	antibiotic biosynthetic process
GGD92_RS03515	COG0583	DNA-binding transcription factor activity
GGD92_RS03530	COG2066	Belongs to the glutaminase family
GGD92_RS03540	COG2233	PERMEase
GGD92_RS03570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGD92_RS03600	COG2194	sulfuric ester hydrolase activity
GGD92_RS03610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GGD92_RS03615	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GGD92_RS03620	COG0561	phosphatase activity
GGD92_RS03625	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GGD92_RS03630	COG2030	dehydratase
GGD92_RS03630	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS03645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGD92_RS03650	COG2151	metal-sulfur cluster biosynthetic enzyme
GGD92_RS03655	COG3396	Phenylacetate-CoA oxygenase
GGD92_RS03660	COG3460	Phenylacetate-CoA oxygenase
GGD92_RS03665	COG3396	Phenylacetate-CoA oxygenase
GGD92_RS03675	COG0183	Belongs to the thiolase family
GGD92_RS03680	COG2050	protein possibly involved in aromatic compounds catabolism
GGD92_RS03685	COG1250	3-hydroxyacyl-CoA dehydrogenase
GGD92_RS03690	COG1024	Enoyl-CoA hydratase
GGD92_RS03695	COG1024	Enoyl-CoA hydratase
GGD92_RS03705	COG3327	negative regulation of DNA-templated transcription, initiation
GGD92_RS03715	COG2204	response regulator
GGD92_RS03760	COG0840	transmembrane signaling receptor activity
GGD92_RS03765	COG1968	undecaprenyl-diphosphatase activity
GGD92_RS03785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGD92_RS03800	COG0488	(ABC) transporter
GGD92_RS03820	COG2133	pyrroloquinoline quinone binding
GGD92_RS03830	COG0189	ligase activity
GGD92_RS03835	COG0598	Magnesium transport protein CorA
GGD92_RS03840	COG0024	Methionine aminopeptidase
GGD92_RS03850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GGD92_RS03895	COG0726	polysaccharide deacetylase
GGD92_RS03905	COG0463	Glycosyl transferase, family 2
GGD92_RS03915	COG0438	transferase activity, transferring glycosyl groups
GGD92_RS03955	COG2207	Transcriptional regulator
GGD92_RS03960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGD92_RS03975	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS03980	COG1024	Enoyl-CoA hydratase
GGD92_RS03990	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS03995	COG1024	Enoyl-CoA hydratase
GGD92_RS04000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS04020	COG1522	sequence-specific DNA binding
GGD92_RS04060	COG2076	Multidrug Resistance protein
GGD92_RS04065	COG2076	Multidrug Resistance protein
GGD92_RS04070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGD92_RS04075	COG0726	polysaccharide deacetylase
GGD92_RS04080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GGD92_RS04080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GGD92_RS04085	COG0463	Glycosyl transferase, family 2
GGD92_RS04090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGD92_RS04095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GGD92_RS04100	COG3842	ATPase activity
GGD92_RS04145	COG4106	trans-aconitate 2-methyltransferase activity
GGD92_RS04155	COG1999	signal sequence binding
GGD92_RS04175	COG1024	Enoyl-CoA hydratase
GGD92_RS04220	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
GGD92_RS04295	COG3188	usher protein
GGD92_RS04300	COG3121	Chaperone
GGD92_RS04330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS04330	COG2205	protein histidine kinase activity
GGD92_RS04335	COG2200	EAL domain
GGD92_RS04335	COG2203	Gaf domain
GGD92_RS04335	COG2199	diguanylate cyclase activity
GGD92_RS04340	COG2197	response regulator
GGD92_RS04365	COG5290	Psort location Cytoplasmic, score
GGD92_RS04395	COG1196	nuclear chromosome segregation
GGD92_RS04410	COG0583	DNA-binding transcription factor activity
GGD92_RS04415	COG2175	clavaminate synthase activity
GGD92_RS04435	COG0577	efflux transmembrane transporter activity
GGD92_RS04435	COG1136	(ABC) transporter
GGD92_RS04440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS04485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGD92_RS04495	COG1301	dicarboxylic acid transport
GGD92_RS04535	COG0438	transferase activity, transferring glycosyl groups
GGD92_RS04560	COG2342	PFAM TM1410 hypothetical-related protein
GGD92_RS04565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GGD92_RS04575	COG2372	response to copper ion
GGD92_RS04600	COG1858	cytochrome C peroxidase
GGD92_RS04625	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GGD92_RS04650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGD92_RS04655	COG0406	alpha-ribazole phosphatase activity
GGD92_RS04660	COG3588	fructose-bisphosphate aldolase
GGD92_RS04665	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
GGD92_RS04685	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GGD92_RS04700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGD92_RS04700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGD92_RS04705	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS04725	COG4566	intracellular signal transduction
GGD92_RS04730	COG0786	glutamate:sodium symporter activity
GGD92_RS04740	COG3046	protein related to deoxyribodipyrimidine photolyase
GGD92_RS04770	COG0826	peptidase U32
GGD92_RS04805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGD92_RS04810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GGD92_RS04825	COG0589	response to stress
GGD92_RS04840	COG0174	glutamine synthetase
GGD92_RS04850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS04855	COG2267	carboxylic ester hydrolase activity
GGD92_RS04865	COG0577	efflux transmembrane transporter activity
GGD92_RS04865	COG1136	(ABC) transporter
GGD92_RS04870	COG1136	(ABC) transporter
GGD92_RS04870	COG0577	efflux transmembrane transporter activity
GGD92_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS04925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGD92_RS04965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGD92_RS04970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGD92_RS04990	COG4977	sequence-specific DNA binding
GGD92_RS04990	COG1917	Cupin 2, conserved barrel domain protein
GGD92_RS04995	COG2011	ABC-type metal ion transport system permease component
GGD92_RS05000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGD92_RS05005	COG1464	Belongs to the NlpA lipoprotein family
GGD92_RS05020	COG0656	L-ascorbic acid biosynthetic process
GGD92_RS05025	COG0784	Response regulator, receiver
GGD92_RS05025	COG2205	protein histidine kinase activity
GGD92_RS05030	COG5001	Diguanylate cyclase
GGD92_RS05030	COG3300	MHYT domain
GGD92_RS05035	COG2205	protein histidine kinase activity
GGD92_RS05035	COG0784	Response regulator, receiver
GGD92_RS05040	COG2197	response regulator
GGD92_RS05050	COG1199	ATP-dependent helicase activity
GGD92_RS05070	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GGD92_RS05070	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GGD92_RS05080	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GGD92_RS05125	COG2207	Transcriptional regulator
GGD92_RS05135	COG0531	amino acid
GGD92_RS05160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GGD92_RS05180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS05195	COG0210	DNA helicase
GGD92_RS05210	COG3321	synthase
GGD92_RS05210	COG0604	alcohol dehydrogenase
GGD92_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS05235	COG0667	Aldo Keto reductase
GGD92_RS05255	COG1204	response to ionizing radiation
GGD92_RS05280	COG2814	Major facilitator Superfamily
GGD92_RS05290	COG0247	lactate metabolic process
GGD92_RS05290	COG0277	FAD linked oxidase domain protein
GGD92_RS05295	COG0583	DNA-binding transcription factor activity
GGD92_RS05330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS05345	COG3781	membrane
GGD92_RS05355	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GGD92_RS05370	COG5002	protein histidine kinase activity
GGD92_RS05370	COG2205	protein histidine kinase activity
GGD92_RS05370	COG0784	Response regulator, receiver
GGD92_RS05380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGD92_RS05400	COG0672	)-iron permease
GGD92_RS05405	COG2822	iron ion transport
GGD92_RS05415	COG2822	iron ion transport
GGD92_RS05420	COG2814	Major facilitator Superfamily
GGD92_RS05425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGD92_RS05440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGD92_RS05455	COG2816	NAD+ diphosphatase activity
GGD92_RS05460	COG1024	Enoyl-CoA hydratase
GGD92_RS05465	COG2205	protein histidine kinase activity
GGD92_RS05470	COG0745	RESPONSE REGULATOR receiver
GGD92_RS05480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGD92_RS05485	COG0583	DNA-binding transcription factor activity
GGD92_RS05490	COG2175	clavaminate synthase activity
GGD92_RS05500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGD92_RS05510	COG2706	6-phosphogluconolactonase activity
GGD92_RS05530	COG0659	secondary active sulfate transmembrane transporter activity
GGD92_RS05535	COG0308	aminopeptidase N
GGD92_RS05545	COG3139	Protein of unknown function (DUF1315)
GGD92_RS05550	COG0705	Rhomboid family
GGD92_RS05555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GGD92_RS05560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GGD92_RS05575	COG0431	NADPH-dependent FMN reductase
GGD92_RS05600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GGD92_RS05610	COG0328	RNA-DNA hybrid ribonuclease activity
GGD92_RS05620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGD92_RS05625	COG0741	lytic transglycosylase activity
GGD92_RS05625	COG1388	LysM domain
GGD92_RS05630	COG4166	transmembrane transport
GGD92_RS05635	COG4166	transmembrane transport
GGD92_RS05640	COG4174	ABC transporter (Permease)
GGD92_RS05645	COG4239	(ABC) transporter, permease
GGD92_RS05650	COG4172	Belongs to the ABC transporter superfamily
GGD92_RS05665	COG2199	diguanylate cyclase activity
GGD92_RS05665	COG2203	Gaf domain
GGD92_RS05680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GGD92_RS05715	COG0784	Response regulator, receiver
GGD92_RS05715	COG0835	chemotaxis
GGD92_RS05720	COG0840	transmembrane signaling receptor activity
GGD92_RS05740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGD92_RS05760	COG1858	cytochrome C peroxidase
GGD92_RS05775	COG3300	MHYT domain
GGD92_RS05775	COG5001	Diguanylate cyclase
GGD92_RS05780	COG0494	nUDIX hydrolase
GGD92_RS05800	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGD92_RS05815	COG1349	DNA-binding transcription factor activity
GGD92_RS05820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGD92_RS05825	COG3622	Belongs to the hyi family
GGD92_RS05830	COG2610	gluconate transmembrane transporter activity
GGD92_RS05835	COG0235	Class ii aldolase
GGD92_RS05840	COG3395	kinase activity
GGD92_RS05845	COG2084	Dehydrogenase
GGD92_RS05920	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GGD92_RS06000	COG4373	Mu-like prophage FluMu protein gp28
GGD92_RS06010	COG2369	cell adhesion
GGD92_RS06040	COG4387	Mu-like prophage protein GP36
GGD92_RS06135	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGD92_RS06150	COG0045	succinate-CoA ligase (ADP-forming) activity
GGD92_RS06155	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS06160	COG1024	Enoyl-CoA hydratase
GGD92_RS06165	COG0833	amino acid
GGD92_RS06190	COG0235	Class ii aldolase
GGD92_RS06200	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGD92_RS06200	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS06290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GGD92_RS06300	COG2828	Protein conserved in bacteria
GGD92_RS06315	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS06340	COG3012	SEC-C Motif Domain Protein
GGD92_RS06340	COG3318	Belongs to the UPF0149 family
GGD92_RS06405	COG2819	hydrolase of the alpha beta superfamily
GGD92_RS06455	COG2301	Belongs to the HpcH HpaI aldolase family
GGD92_RS06465	COG2079	MmgE PrpD family protein
GGD92_RS06475	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GGD92_RS06480	COG0583	DNA-binding transcription factor activity
GGD92_RS06505	COG0714	Associated with various cellular activities
GGD92_RS06520	COG2205	protein histidine kinase activity
GGD92_RS06525	COG0745	RESPONSE REGULATOR receiver
GGD92_RS06535	COG0589	response to stress
GGD92_RS06560	COG0814	amino acid
GGD92_RS06565	COG1335	isochorismatase
GGD92_RS06570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGD92_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS06585	COG0673	inositol 2-dehydrogenase activity
GGD92_RS06655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GGD92_RS06655	COG2111	Na H antiporter
GGD92_RS06660	COG1006	Multisubunit Na H antiporter MnhC subunit
GGD92_RS06665	COG0651	ATP synthesis coupled electron transport
GGD92_RS06675	COG2212	antiporter activity
GGD92_RS06695	COG4774	siderophore transport
GGD92_RS06735	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGD92_RS06740	COG1129	ABC transporter
GGD92_RS06755	COG0673	inositol 2-dehydrogenase activity
GGD92_RS06760	COG3962	Belongs to the TPP enzyme family
GGD92_RS06775	COG3718	enzyme involved in inositol metabolism
GGD92_RS06810	COG2814	Major facilitator Superfamily
GGD92_RS06820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS06825	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGD92_RS06830	COG3383	formate dehydrogenase (NAD+) activity
GGD92_RS06850	COG0745	RESPONSE REGULATOR receiver
GGD92_RS06855	COG5002	protein histidine kinase activity
GGD92_RS06905	COG3339	Conserved Protein
GGD92_RS06910	COG4804	nuclease activity
GGD92_RS06955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGD92_RS06965	COG4175	Glycine betaine
GGD92_RS06970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGD92_RS06985	COG1953	Uracil, thiamine, allantoin
GGD92_RS07005	COG1309	transcriptional regulator
GGD92_RS07015	COG2372	response to copper ion
GGD92_RS07035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGD92_RS07040	COG0471	metal ion transport
GGD92_RS07055	COG1522	sequence-specific DNA binding
GGD92_RS07060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GGD92_RS07065	COG0022	dehydrogenase e1 component
GGD92_RS07075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGD92_RS07080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGD92_RS07105	COG1305	Transglutaminase-like
GGD92_RS07115	COG2308	Evidence 4 Homologs of previously reported genes of
GGD92_RS07120	COG0529	Catalyzes the synthesis of activated sulfate
GGD92_RS07125	COG5001	Diguanylate cyclase
GGD92_RS07125	COG1716	ATPase activity
GGD92_RS07130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS07130	COG2205	protein histidine kinase activity
GGD92_RS07135	COG0640	Transcriptional regulator
GGD92_RS07150	COG0583	DNA-binding transcription factor activity
GGD92_RS07160	COG1230	cation diffusion facilitator family transporter
GGD92_RS07190	COG1704	LemA family
GGD92_RS07195	COG0501	Belongs to the peptidase M48B family
GGD92_RS07205	COG2851	Citrate transporter
GGD92_RS07210	COG1301	dicarboxylic acid transport
GGD92_RS07215	COG2828	Protein conserved in bacteria
GGD92_RS07220	COG0583	DNA-binding transcription factor activity
GGD92_RS07225	COG0475	glutathione-regulated potassium exporter activity
GGD92_RS07225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGD92_RS07230	COG4335	DNA alkylation repair
GGD92_RS07235	COG3038	cytochrome b561
GGD92_RS07245	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS07295	COG0477	Major facilitator Superfamily
GGD92_RS07325	COG0417	DNA replication proofreading
GGD92_RS07340	COG3224	Antibiotic biosynthesis monooxygenase
GGD92_RS07350	COG1335	isochorismatase
GGD92_RS07355	COG0583	DNA-binding transcription factor activity
GGD92_RS07370	COG0174	glutamine synthetase
GGD92_RS07375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS07455	COG1335	isochorismatase
GGD92_RS07460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GGD92_RS07475	COG0583	DNA-binding transcription factor activity
GGD92_RS07480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGD92_RS07490	COG0745	RESPONSE REGULATOR receiver
GGD92_RS07495	COG3706	GGDEF domain
GGD92_RS07510	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GGD92_RS07525	COG1611	Belongs to the LOG family
GGD92_RS07535	COG1053	succinate dehydrogenase
GGD92_RS07565	COG0534	Mate efflux family protein
GGD92_RS07575	COG0668	transmembrane transport
GGD92_RS07590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGD92_RS07590	COG0116	Belongs to the methyltransferase superfamily
GGD92_RS07615	COG2186	Transcriptional regulator
GGD92_RS07620	COG0579	oxidoreductase
GGD92_RS07630	COG1349	DNA-binding transcription factor activity
GGD92_RS07640	COG0579	oxidoreductase
GGD92_RS07670	COG1064	alcohol dehydrogenase
GGD92_RS07740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS07745	COG0697	spore germination
GGD92_RS07755	COG0625	glutathione transferase activity
GGD92_RS07790	COG2816	NAD+ diphosphatase activity
GGD92_RS07835	COG0525	valine-tRNA ligase activity
GGD92_RS07850	COG1073	alpha beta
GGD92_RS07855	COG2207	Transcriptional regulator
GGD92_RS07875	COG0640	Transcriptional regulator
GGD92_RS07880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGD92_RS07885	COG0431	NADPH-dependent FMN reductase
GGD92_RS07890	COG2384	SAM-dependent methyltransferase
GGD92_RS07910	COG1629	transport
GGD92_RS07915	COG3712	iron ion homeostasis
GGD92_RS07920	COG1595	DNA-templated transcription, initiation
GGD92_RS07930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGD92_RS07940	COG0765	amino acid transport
GGD92_RS07945	COG0765	amino acid transport
GGD92_RS07970	COG3188	usher protein
GGD92_RS07990	COG3121	Chaperone
GGD92_RS07995	COG2197	response regulator
GGD92_RS08000	COG5001	Diguanylate cyclase
GGD92_RS08000	COG5002	protein histidine kinase activity
GGD92_RS08005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS08005	COG2205	protein histidine kinase activity
GGD92_RS08085	COG1396	sequence-specific DNA binding
GGD92_RS08085	COG1917	Cupin 2, conserved barrel domain protein
GGD92_RS08090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS08095	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS08100	COG0174	glutamine synthetase
GGD92_RS08105	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GGD92_RS08110	COG3842	ATPase activity
GGD92_RS08115	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGD92_RS08120	COG1177	transmembrane transport
GGD92_RS08145	COG0517	IMP dehydrogenase activity
GGD92_RS08170	COG1477	protein flavinylation
GGD92_RS08180	COG1368	sulfuric ester hydrolase activity
GGD92_RS08190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGD92_RS08195	COG0583	DNA-binding transcription factor activity
GGD92_RS08200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGD92_RS08215	COG0583	DNA-binding transcription factor activity
GGD92_RS08250	COG0430	RNA-3'-phosphate cyclase activity
GGD92_RS08255	COG3541	Predicted nucleotidyltransferase
GGD92_RS08270	COG1690	Belongs to the RtcB family
GGD92_RS08280	COG4650	regulator
GGD92_RS08295	COG0124	histidyl-tRNA synthetase
GGD92_RS08310	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS08325	COG3712	iron ion homeostasis
GGD92_RS08330	COG1595	DNA-templated transcription, initiation
GGD92_RS08335	COG0113	porphobilinogen synthase activity
GGD92_RS08345	COG0384	phenazine biosynthesis protein PhzF
GGD92_RS08350	COG0625	glutathione transferase activity
GGD92_RS08360	COG0701	Predicted permease
GGD92_RS08370	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GGD92_RS08375	COG0709	Synthesizes selenophosphate from selenide and ATP
GGD92_RS08385	COG0583	DNA-binding transcription factor activity
GGD92_RS08395	COG3971	2-oxopent-4-enoate hydratase activity
GGD92_RS08405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GGD92_RS08420	COG1917	Cupin 2, conserved barrel domain protein
GGD92_RS08430	COG2271	Major facilitator Superfamily
GGD92_RS08445	COG1113	amino acid transport
GGD92_RS08465	COG1063	alcohol dehydrogenase
GGD92_RS08490	COG0277	FAD linked oxidase domain protein
GGD92_RS08495	COG0277	FAD linked oxidase domain protein
GGD92_RS08500	COG0247	lactate metabolic process
GGD92_RS08525	COG3011	Protein conserved in bacteria
GGD92_RS08550	COG1917	Cupin 2, conserved barrel domain protein
GGD92_RS08550	COG4977	sequence-specific DNA binding
GGD92_RS08585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS08590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGD92_RS08625	COG0174	glutamine synthetase
GGD92_RS08635	COG0531	amino acid
GGD92_RS08665	COG3706	GGDEF domain
GGD92_RS08670	COG5383	Protein conserved in bacteria
GGD92_RS08675	COG0277	FAD linked oxidase domain protein
GGD92_RS08720	COG0631	protein serine/threonine phosphatase activity
GGD92_RS08755	COG2204	response regulator
GGD92_RS08840	COG1136	(ABC) transporter
GGD92_RS08850	COG4191	Histidine kinase
GGD92_RS08925	COG3851	Histidine kinase
GGD92_RS08940	COG1131	(ABC) transporter
GGD92_RS08960	COG0784	Response regulator, receiver
GGD92_RS08960	COG2205	protein histidine kinase activity
GGD92_RS08990	COG4215	(ABC) transporter
GGD92_RS09000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS09005	COG1126	abc transporter atp-binding protein
GGD92_RS09045	COG2345	Transcriptional regulator
GGD92_RS09050	COG0561	phosphatase activity
GGD92_RS09070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGD92_RS09115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGD92_RS09120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGD92_RS09190	COG1063	alcohol dehydrogenase
GGD92_RS09200	COG0022	dehydrogenase e1 component
GGD92_RS09205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GGD92_RS09210	COG3199	ATP-NAD kinase
GGD92_RS09215	COG3284	Transcriptional regulator
GGD92_RS09225	COG1250	3-hydroxyacyl-CoA dehydrogenase
GGD92_RS09230	COG1309	transcriptional regulator
GGD92_RS09235	COG4566	intracellular signal transduction
GGD92_RS09240	COG4191	Histidine kinase
GGD92_RS09245	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS09250	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS09300	COG0535	radical SAM domain protein
GGD92_RS09345	COG0114	fumarate hydratase activity
GGD92_RS09375	COG0583	DNA-binding transcription factor activity
GGD92_RS09425	COG0776	regulation of translation
GGD92_RS09430	COG0072	phenylalanine-tRNA ligase activity
GGD92_RS09435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GGD92_RS09440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GGD92_RS09445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GGD92_RS09450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GGD92_RS09455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GGD92_RS09465	COG1278	Cold shock
GGD92_RS09490	COG1869	D-ribose catabolic process
GGD92_RS09495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGD92_RS09500	COG1609	Transcriptional regulator
GGD92_RS09505	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGD92_RS09510	COG1129	ABC transporter
GGD92_RS09545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GGD92_RS09555	COG3469	chitinase activity
GGD92_RS09560	COG3397	chitin binding
GGD92_RS09570	COG1690	Belongs to the RtcB family
GGD92_RS09575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GGD92_RS09585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS09620	COG1286	toxin biosynthetic process
GGD92_RS09625	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGD92_RS09630	COG0285	dihydrofolate synthase activity
GGD92_RS09635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGD92_RS09640	COG0135	phosphoribosylanthranilate isomerase activity
GGD92_RS09665	COG0473	3-isopropylmalate dehydrogenase activity
GGD92_RS09670	COG2226	methyltransferase
GGD92_RS09675	COG0066	3-isopropylmalate dehydratase activity
GGD92_RS09680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GGD92_RS09700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGD92_RS09710	COG0596	Alpha beta hydrolase
GGD92_RS09750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GGD92_RS09765	COG0556	nucleotide-excision repair
GGD92_RS09800	COG2233	PERMEase
GGD92_RS09820	COG4251	negative regulation of phosphorylation
GGD92_RS09820	COG3706	GGDEF domain
GGD92_RS09820	COG2203	Gaf domain
GGD92_RS09820	COG5001	Diguanylate cyclase
GGD92_RS09825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGD92_RS09830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GGD92_RS09840	COG2204	response regulator
GGD92_RS09850	COG2853	Lipoprotein
GGD92_RS09865	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGD92_RS09865	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGD92_RS09885	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGD92_RS09890	COG1136	(ABC) transporter
GGD92_RS09895	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGD92_RS09905	COG0584	glycerophosphoryl diester phosphodiesterase
GGD92_RS09910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGD92_RS09915	COG1477	protein flavinylation
GGD92_RS09930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGD92_RS09940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGD92_RS10000	COG0183	Belongs to the thiolase family
GGD92_RS10005	COG1024	Enoyl-CoA hydratase
GGD92_RS10005	COG1250	3-hydroxyacyl-CoA dehydrogenase
GGD92_RS10015	COG0589	response to stress
GGD92_RS10020	COG0488	(ABC) transporter
GGD92_RS10025	COG0741	lytic transglycosylase activity
GGD92_RS10030	COG1132	(ABC) transporter
GGD92_RS10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGD92_RS10050	COG0425	Belongs to the sulfur carrier protein TusA family
GGD92_RS10055	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GGD92_RS10070	COG0840	transmembrane signaling receptor activity
GGD92_RS10080	COG3278	Belongs to the heme-copper respiratory oxidase family
GGD92_RS10100	COG3278	Belongs to the heme-copper respiratory oxidase family
GGD92_RS10115	COG2010	Cytochrome c
GGD92_RS10120	COG0348	domain, Protein
GGD92_RS10130	COG2217	Heavy metal translocating P-type atpase
GGD92_RS10155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGD92_RS10160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGD92_RS10165	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS10170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GGD92_RS10175	COG2130	NADP-dependent
GGD92_RS10180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GGD92_RS10185	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GGD92_RS10200	COG0840	transmembrane signaling receptor activity
GGD92_RS10220	COG0697	spore germination
GGD92_RS10225	COG0583	DNA-binding transcription factor activity
GGD92_RS10230	COG1881	PFAM PEBP family protein
GGD92_RS10235	COG2207	Transcriptional regulator
GGD92_RS10240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GGD92_RS10260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GGD92_RS10265	COG3115	cell septum assembly
GGD92_RS10295	COG0402	S-adenosylhomocysteine deaminase activity
GGD92_RS10305	COG0583	DNA-binding transcription factor activity
GGD92_RS10310	COG1802	Transcriptional regulator
GGD92_RS10315	COG3135	benzoate transporter
GGD92_RS10320	COG3171	Protein conserved in bacteria
GGD92_RS10325	COG2027	D-alanyl-D-alanine carboxypeptidase
GGD92_RS10335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGD92_RS10335	COG0116	Belongs to the methyltransferase superfamily
GGD92_RS10340	COG3130	regulation of translation
GGD92_RS10345	COG0167	dihydroorotate dehydrogenase activity
GGD92_RS10350	COG2885	chlorophyll binding
GGD92_RS10350	COG3047	cAMP biosynthetic process
GGD92_RS10360	COG0668	transmembrane transport
GGD92_RS10375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGD92_RS10390	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GGD92_RS10395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS10405	COG2079	MmgE PrpD family protein
GGD92_RS10420	COG0372	Belongs to the citrate synthase family
GGD92_RS10430	COG1802	Transcriptional regulator
GGD92_RS10435	COG0189	ligase activity
GGD92_RS10435	COG4067	protein conserved in archaea
GGD92_RS10455	COG0560	Phosphoserine phosphatase
GGD92_RS10465	COG1953	Uracil, thiamine, allantoin
GGD92_RS10475	COG0583	DNA-binding transcription factor activity
GGD92_RS10480	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS10485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGD92_RS10525	COG0598	Magnesium transport protein CorA
GGD92_RS10530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GGD92_RS10530	COG0519	Catalyzes the synthesis of GMP from XMP
GGD92_RS10535	COG1024	Enoyl-CoA hydratase
GGD92_RS10535	COG1250	3-hydroxyacyl-CoA dehydrogenase
GGD92_RS10540	COG0183	Belongs to the thiolase family
GGD92_RS10575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS10580	COG2885	chlorophyll binding
GGD92_RS10580	COG3047	cAMP biosynthetic process
GGD92_RS10615	COG2207	Transcriptional regulator
GGD92_RS10620	COG1064	alcohol dehydrogenase
GGD92_RS10630	COG1418	mRNA catabolic process
GGD92_RS10645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGD92_RS10655	COG1397	ADP-ribosylglycohydrolase
GGD92_RS10660	COG2186	Transcriptional regulator
GGD92_RS10675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GGD92_RS10690	COG0084	hydrolase, TatD family'
GGD92_RS10700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GGD92_RS10705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GGD92_RS10715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGD92_RS10720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GGD92_RS10735	COG0416	fatty acid biosynthetic process
GGD92_RS10740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GGD92_RS10750	COG0424	maF-like protein
GGD92_RS10755	COG0616	signal peptide processing
GGD92_RS10755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GGD92_RS10760	COG0546	phosphoglycolate phosphatase activity
GGD92_RS10770	COG1530	ribonuclease E activity
GGD92_RS10780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GGD92_RS10780	COG3608	succinylglutamate desuccinylase aspartoacylase
GGD92_RS10785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GGD92_RS10795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GGD92_RS10800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGD92_RS10805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GGD92_RS10810	COG2835	tetraacyldisaccharide 4'-kinase activity
GGD92_RS10815	COG1663	tetraacyldisaccharide 4'-kinase activity
GGD92_RS10825	COG0811	peptide transport
GGD92_RS10830	COG2333	competence protein COMEC
GGD92_RS10830	COG0658	competence protein
GGD92_RS10840	COG0842	Transport permease protein
GGD92_RS10845	COG1131	(ABC) transporter
GGD92_RS10850	COG0625	glutathione transferase activity
GGD92_RS10920	COG0840	transmembrane signaling receptor activity
GGD92_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS10930	COG2130	NADP-dependent
GGD92_RS10935	COG0284	orotidine-5'-phosphate decarboxylase activity
GGD92_RS10945	COG2205	protein histidine kinase activity
GGD92_RS10955	COG0628	permease
GGD92_RS10965	COG0625	glutathione transferase activity
GGD92_RS10985	COG1022	Amp-dependent synthetase and ligase
GGD92_RS10990	COG2062	phosphohistidine phosphatase, SixA
GGD92_RS11000	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GGD92_RS11005	COG4771	TonB-dependent receptor
GGD92_RS11015	COG5002	protein histidine kinase activity
GGD92_RS11015	COG0784	Response regulator, receiver
GGD92_RS11015	COG2205	protein histidine kinase activity
GGD92_RS11020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGD92_RS11030	COG0840	transmembrane signaling receptor activity
GGD92_RS11040	COG1741	Belongs to the pirin family
GGD92_RS11050	COG0326	Molecular chaperone. Has ATPase activity
GGD92_RS11090	COG0045	succinate-CoA ligase (ADP-forming) activity
GGD92_RS11095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGD92_RS11115	COG1053	succinate dehydrogenase
GGD92_RS11120	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GGD92_RS11125	COG2009	succinate dehydrogenase
GGD92_RS11135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGD92_RS11140	COG3162	membrane
GGD92_RS11145	COG2113	Glycine betaine
GGD92_RS11165	COG2853	Lipoprotein
GGD92_RS11170	COG2354	Protein conserved in bacteria
GGD92_RS11175	COG1309	transcriptional regulator
GGD92_RS11185	COG3960	tartronate-semialdehyde synthase activity
GGD92_RS11190	COG3622	Belongs to the hyi family
GGD92_RS11195	COG2084	Dehydrogenase
GGD92_RS11205	COG0469	pyruvate kinase activity
GGD92_RS11215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGD92_RS11235	COG2814	Major facilitator Superfamily
GGD92_RS11260	COG3088	subunit of a heme lyase
GGD92_RS11270	COG1138	Cytochrome C-type biogenesis protein
GGD92_RS11275	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GGD92_RS11295	COG4133	protoheme IX ABC transporter activity
GGD92_RS11315	COG0835	chemotaxis
GGD92_RS11325	COG1192	Involved in chromosome partitioning
GGD92_RS11335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGD92_RS11340	COG2201	protein-glutamate methylesterase activity
GGD92_RS11345	COG0784	Response regulator, receiver
GGD92_RS11345	COG0643	Histidine kinase
GGD92_RS11345	COG2198	Histidine kinase
GGD92_RS11350	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GGD92_RS11430	COG0745	RESPONSE REGULATOR receiver
GGD92_RS11465	COG1677	Flagellar hook-basal body complex protein FliE
GGD92_RS11500	COG1334	flagellar protein FlaG
GGD92_RS11505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGD92_RS11520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGD92_RS11525	COG2089	acid synthase
GGD92_RS11535	COG1083	cytidylyl-transferase
GGD92_RS11540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGD92_RS11545	COG1086	Polysaccharide biosynthesis protein
GGD92_RS11550	COG0438	transferase activity, transferring glycosyl groups
GGD92_RS11550	COG1216	Glycosyl transferase, family 2
GGD92_RS11560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGD92_RS11585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GGD92_RS11590	COG1216	Glycosyl transferase, family 2
GGD92_RS11590	COG0438	transferase activity, transferring glycosyl groups
GGD92_RS11600	COG1256	bacterial-type flagellum assembly
GGD92_RS11610	COG1706	bacterial-type flagellum-dependent cell motility
GGD92_RS11615	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGD92_RS11625	COG4786	Flagellar basal body rod
GGD92_RS11640	COG2154	pterin-4-alpha-carbinolamine dehydratase
GGD92_RS11685	COG1113	amino acid transport
GGD92_RS11710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GGD92_RS11715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GGD92_RS11720	COG0009	L-threonylcarbamoyladenylate synthase
GGD92_RS11730	COG2917	probably involved in intracellular septation
GGD92_RS11735	COG2350	Protein conserved in bacteria
GGD92_RS11745	COG0745	RESPONSE REGULATOR receiver
GGD92_RS11755	COG0642	Histidine kinase
GGD92_RS11765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGD92_RS11805	COG1752	Esterase of the alpha-beta hydrolase superfamily
GGD92_RS11825	COG2832	Protein of unknown function (DUF454)
GGD92_RS11845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGD92_RS11850	COG0583	DNA-binding transcription factor activity
GGD92_RS11860	COG0697	spore germination
GGD92_RS11955	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGD92_RS11960	COG0513	Belongs to the DEAD box helicase family
GGD92_RS11965	COG0668	transmembrane transport
GGD92_RS11975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGD92_RS12000	COG1132	(ABC) transporter
GGD92_RS12005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGD92_RS12030	COG2188	Transcriptional regulator
GGD92_RS12040	COG1595	DNA-templated transcription, initiation
GGD92_RS12050	COG1643	Atp-dependent helicase
GGD92_RS12055	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GGD92_RS12085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GGD92_RS12095	COG0542	response to heat
GGD92_RS12105	COG1984	allophanate hydrolase subunit 2
GGD92_RS12110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GGD92_RS12115	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GGD92_RS12120	COG2814	Major facilitator Superfamily
GGD92_RS12125	COG0583	DNA-binding transcription factor activity
GGD92_RS12135	COG0121	glutamine amidotransferase
GGD92_RS12185	COG2983	Belongs to the UPF0260 family
GGD92_RS12195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGD92_RS12200	COG3100	YcgL domain-containing protein
GGD92_RS12220	COG0583	DNA-binding transcription factor activity
GGD92_RS12230	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GGD92_RS12235	COG2807	transmembrane transport
GGD92_RS12245	COG0583	DNA-binding transcription factor activity
GGD92_RS12270	COG3210	domain, Protein
GGD92_RS12280	COG3121	Chaperone
GGD92_RS12285	COG3188	usher protein
GGD92_RS12290	COG3121	Chaperone
GGD92_RS12315	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GGD92_RS12320	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GGD92_RS12325	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GGD92_RS12330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGD92_RS12335	COG2716	regulation of RNA biosynthetic process
GGD92_RS12340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GGD92_RS12350	COG0425	Belongs to the sulfur carrier protein TusA family
GGD92_RS12360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGD92_RS12390	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GGD92_RS12440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GGD92_RS12470	COG2267	carboxylic ester hydrolase activity
GGD92_RS12490	COG5001	Diguanylate cyclase
GGD92_RS12520	COG4774	siderophore transport
GGD92_RS12525	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GGD92_RS12535	COG0531	amino acid
GGD92_RS12540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGD92_RS12545	COG3938	Belongs to the proline racemase family
GGD92_RS12610	COG1454	alcohol dehydrogenase
GGD92_RS12620	COG1396	sequence-specific DNA binding
GGD92_RS12625	COG0235	Class ii aldolase
GGD92_RS12630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGD92_RS12650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGD92_RS12685	COG0251	oxidation-reduction process
GGD92_RS12720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGD92_RS12725	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS12730	COG1116	anion transmembrane transporter activity
GGD92_RS12735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGD92_RS12740	COG0583	DNA-binding transcription factor activity
GGD92_RS12755	COG1595	DNA-templated transcription, initiation
GGD92_RS12765	COG1629	transport
GGD92_RS12785	COG0693	protein deglycase activity
GGD92_RS12800	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GGD92_RS12810	COG1704	LemA family
GGD92_RS12820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGD92_RS12835	COG0154	amidase activity
GGD92_RS12845	COG1473	amidohydrolase
GGD92_RS12885	COG2814	Major facilitator Superfamily
GGD92_RS12890	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS12905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS12945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGD92_RS12950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGD92_RS12960	COG0477	Major facilitator Superfamily
GGD92_RS12965	COG3485	protocatechuate 3,4-dioxygenase
GGD92_RS12970	COG3485	protocatechuate 3,4-dioxygenase
GGD92_RS12975	COG0183	Belongs to the thiolase family
GGD92_RS12980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GGD92_RS12985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGD92_RS12990	COG2814	Major facilitator Superfamily
GGD92_RS12995	COG1414	Transcriptional regulator
GGD92_RS13005	COG0306	phosphate transporter
GGD92_RS13015	COG0583	DNA-binding transcription factor activity
GGD92_RS13035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGD92_RS13040	COG2271	Major facilitator Superfamily
GGD92_RS13045	COG0727	PFAM Uncharacterised protein family (UPF0153)
GGD92_RS13055	COG2084	Dehydrogenase
GGD92_RS13100	COG3220	belongs to the UPF0276 family
GGD92_RS13130	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GGD92_RS13140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GGD92_RS13155	COG0259	pyridoxamine-phosphate oxidase activity
GGD92_RS13165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GGD92_RS13175	COG1199	ATP-dependent helicase activity
GGD92_RS13205	COG3012	SEC-C Motif Domain Protein
GGD92_RS13215	COG0653	protein targeting
GGD92_RS13225	COG2366	antibiotic biosynthetic process
GGD92_RS13250	COG4598	ABC transporter
GGD92_RS13260	COG0717	Belongs to the dCTP deaminase family
GGD92_RS13265	COG1278	Cold shock
GGD92_RS13285	COG0442	prolyl-tRNA aminoacylation
GGD92_RS13295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGD92_RS13310	COG0392	lysyltransferase activity
GGD92_RS13310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GGD92_RS13325	COG3158	transport of potassium into the cell
GGD92_RS13330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GGD92_RS13345	COG4807	Protein conserved in bacteria
GGD92_RS13360	COG0583	DNA-binding transcription factor activity
GGD92_RS13380	COG3148	PFAM DTW domain containing protein
GGD92_RS13400	COG2137	regulation of response to DNA damage stimulus
GGD92_RS13405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GGD92_RS13410	COG1546	Belongs to the CinA family
GGD92_RS13425	COG3179	chitinase
GGD92_RS13460	COG4381	Mu-like prophage protein gp46
GGD92_RS13495	COG4386	tail sheath protein
GGD92_RS13680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GGD92_RS13700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GGD92_RS13705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GGD92_RS13710	COG0585	pseudouridine synthase activity
GGD92_RS13715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GGD92_RS13720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GGD92_RS13725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GGD92_RS13735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GGD92_RS13745	COG0148	phosphopyruvate hydratase activity
GGD92_RS13750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GGD92_RS13755	COG0504	CTP synthase activity
GGD92_RS13760	COG0037	tRNA processing
GGD92_RS13765	COG0825	malonyl-CoA metabolic process
GGD92_RS13770	COG0587	DNA-directed DNA polymerase activity
GGD92_RS13775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGD92_RS13780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGD92_RS13785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGD92_RS13790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGD92_RS13795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGD92_RS13815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GGD92_RS13825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GGD92_RS13830	COG0233	cytoplasmic translational termination
GGD92_RS13835	COG0528	UMP kinase activity
GGD92_RS13840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GGD92_RS13845	COG0052	Belongs to the universal ribosomal protein uS2 family
GGD92_RS13850	COG0024	Methionine aminopeptidase
GGD92_RS13855	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GGD92_RS13860	COG0436	Aminotransferase
GGD92_RS13865	COG0025	NhaP-type Na H and K H
GGD92_RS13870	COG1393	Belongs to the ArsC family
GGD92_RS13875	COG2171	N-acyltransferase activity
GGD92_RS13880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGD92_RS13890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GGD92_RS13900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGD92_RS13905	COG2226	methyltransferase
GGD92_RS13920	COG2937	Belongs to the GPAT DAPAT family
GGD92_RS13935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGD92_RS13940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS13950	COG0742	ribosomal rna small subunit methyltransferase
GGD92_RS13970	COG1801	Protein of unknown function DUF72
GGD92_RS13980	COG1214	PFAM Peptidase M22, glycoprotease
GGD92_RS13985	COG0563	adenylate kinase activity
GGD92_RS13990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GGD92_RS14005	COG2885	chlorophyll binding
GGD92_RS14015	COG1073	alpha beta
GGD92_RS14035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GGD92_RS14050	COG3706	GGDEF domain
GGD92_RS14050	COG4251	negative regulation of phosphorylation
GGD92_RS14050	COG5001	Diguanylate cyclase
GGD92_RS14050	COG2203	Gaf domain
GGD92_RS14055	COG2201	protein-glutamate methylesterase activity
GGD92_RS14070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGD92_RS14070	COG0457	Tetratricopeptide repeat
GGD92_RS14085	COG2979	Protein of unknown function (DUF533)
GGD92_RS14090	COG0583	DNA-binding transcription factor activity
GGD92_RS14100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGD92_RS14105	COG3842	ATPase activity
GGD92_RS14110	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGD92_RS14115	COG1177	transmembrane transport
GGD92_RS14120	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS14135	COG2311	Membrane
GGD92_RS14145	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GGD92_RS14150	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS14200	COG1842	Phage shock protein A
GGD92_RS14210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GGD92_RS14240	COG4974	Belongs to the 'phage' integrase family
GGD92_RS14250	COG1607	acyl-coa hydrolase
GGD92_RS14255	COG0335	large ribosomal subunit rRNA binding
GGD92_RS14260	COG0336	Belongs to the RNA methyltransferase TrmD family
GGD92_RS14265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GGD92_RS14270	COG0228	four-way junction DNA binding
GGD92_RS14275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGD92_RS14285	COG4536	flavin adenine dinucleotide binding
GGD92_RS14290	COG0477	Major facilitator Superfamily
GGD92_RS14295	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GGD92_RS14330	COG2188	Transcriptional regulator
GGD92_RS14335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GGD92_RS14340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GGD92_RS14345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGD92_RS14345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGD92_RS14350	COG1263	PTS System
GGD92_RS14350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGD92_RS14350	COG2190	(PTS) system
GGD92_RS14360	COG0047	phosphoribosylformylglycinamidine synthase activity
GGD92_RS14360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GGD92_RS14365	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGD92_RS14370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GGD92_RS14375	COG1381	Involved in DNA repair and RecF pathway recombination
GGD92_RS14380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GGD92_RS14385	COG0571	ribonuclease III activity
GGD92_RS14390	COG0681	Belongs to the peptidase S26 family
GGD92_RS14395	COG0481	GTPase activity
GGD92_RS14400	COG0795	lipopolysaccharide-transporting ATPase activity
GGD92_RS14405	COG0795	lipopolysaccharide-transporting ATPase activity
GGD92_RS14410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GGD92_RS14425	COG0525	valine-tRNA ligase activity
GGD92_RS14430	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GGD92_RS14440	COG3081	Nucleoid-associated protein
GGD92_RS14455	COG2827	Endonuclease containing a URI domain
GGD92_RS14465	COG2807	transmembrane transport
GGD92_RS14470	COG2186	Transcriptional regulator
GGD92_RS14485	COG1126	abc transporter atp-binding protein
GGD92_RS14490	COG0765	amino acid transport
GGD92_RS14495	COG4597	amino acid ABC transporter
GGD92_RS14500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS14510	COG0513	Belongs to the DEAD box helicase family
GGD92_RS14530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS14540	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GGD92_RS14545	COG0315	cyclic pyranopterin monophosphate synthase activity
GGD92_RS14560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GGD92_RS14570	COG3022	response to hydroperoxide
GGD92_RS14580	COG1215	transferase activity, transferring glycosyl groups
GGD92_RS14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS14590	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GGD92_RS14600	COG3420	alginic acid biosynthetic process
GGD92_RS14615	COG1696	Membrane protein involved in D-alanine export
GGD92_RS14630	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GGD92_RS14630	COG0662	Cupin 2, conserved barrel domain protein
GGD92_RS14665	COG0300	oxidoreductase activity
GGD92_RS14675	COG1566	PFAM secretion protein HlyD family protein
GGD92_RS14695	COG0583	DNA-binding transcription factor activity
GGD92_RS14730	COG4774	siderophore transport
GGD92_RS14735	COG0737	Belongs to the 5'-nucleotidase family
GGD92_RS14735	COG4085	toxin activity
GGD92_RS14735	COG1525	nuclease
GGD92_RS14740	COG0811	peptide transport
GGD92_RS14770	COG1595	DNA-templated transcription, initiation
GGD92_RS14775	COG3712	iron ion homeostasis
GGD92_RS14780	COG4772	TonB-dependent receptor
GGD92_RS14790	COG0583	DNA-binding transcription factor activity
GGD92_RS14795	COG1760	l-serine dehydratase
GGD92_RS14800	COG0814	amino acid
GGD92_RS14825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GGD92_RS14850	COG0179	Fumarylacetoacetate (FAA) hydrolase
GGD92_RS14855	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GGD92_RS14865	COG2197	response regulator
GGD92_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS14900	COG1346	cytolysis
GGD92_RS14905	COG1380	Effector of murein hydrolase LrgA
GGD92_RS14910	COG0583	DNA-binding transcription factor activity
GGD92_RS14920	COG1366	Belongs to the anti-sigma-factor antagonist family
GGD92_RS14930	COG0789	Transcriptional regulator
GGD92_RS14950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGD92_RS14965	COG0492	ferredoxin-NADP+ reductase activity
GGD92_RS14970	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GGD92_RS14985	COG0386	Belongs to the glutathione peroxidase family
GGD92_RS14990	COG1047	Peptidyl-prolyl cis-trans
GGD92_RS15000	COG0280	phosphate acetyltransferase
GGD92_RS15000	COG0857	belongs to the CobB CobQ family
GGD92_RS15005	COG0204	Acyl-transferase
GGD92_RS15015	COG0175	sulfate reduction
GGD92_RS15025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGD92_RS15040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GGD92_RS15045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGD92_RS15050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GGD92_RS15055	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GGD92_RS15075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GGD92_RS15080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GGD92_RS15085	COG1127	ABC transporter
GGD92_RS15095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GGD92_RS15105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GGD92_RS15110	COG1137	ATPase activity
GGD92_RS15115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GGD92_RS15130	COG1660	Displays ATPase and GTPase activities
GGD92_RS15165	COG0312	modulator of DNA gyrase
GGD92_RS15170	COG3028	Belongs to the UPF0307 family
GGD92_RS15175	COG0312	modulator of DNA gyrase
GGD92_RS15180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGD92_RS15190	COG1530	ribonuclease E activity
GGD92_RS15195	COG0424	maF-like protein
GGD92_RS15200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GGD92_RS15205	COG1792	Involved in formation and maintenance of cell shape
GGD92_RS15210	COG1077	Cell shape determining protein MreB Mrl
GGD92_RS15215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GGD92_RS15220	COG0154	amidase activity
GGD92_RS15225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GGD92_RS15230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGD92_RS15240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGD92_RS15260	COG4178	(ABC) transporter
GGD92_RS15265	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GGD92_RS15280	COG1917	Cupin 2, conserved barrel domain protein
GGD92_RS15280	COG1396	sequence-specific DNA binding
GGD92_RS15285	COG0747	negative chemotaxis
GGD92_RS15290	COG0747	negative chemotaxis
GGD92_RS15300	COG0747	negative chemotaxis
GGD92_RS15305	COG0601	transmembrane transport
GGD92_RS15310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGD92_RS15315	COG0444	Belongs to the ABC transporter superfamily
GGD92_RS15320	COG4608	Belongs to the ABC transporter superfamily
GGD92_RS15330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GGD92_RS15355	COG0019	diaminopimelate decarboxylase activity
GGD92_RS15370	COG3128	pkhd-type hydroxylase
GGD92_RS15375	COG4774	siderophore transport
GGD92_RS15380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGD92_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS15405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGD92_RS15405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGD92_RS15405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGD92_RS15410	COG1105	Belongs to the carbohydrate kinase PfkB family
GGD92_RS15415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGD92_RS15415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGD92_RS15420	COG1609	Transcriptional regulator
GGD92_RS15425	COG0084	hydrolase, TatD family'
GGD92_RS15445	COG3023	N-Acetylmuramoyl-L-alanine amidase
GGD92_RS15530	COG0582	viral genome integration into host DNA
GGD92_RS15540	COG1185	polyribonucleotide nucleotidyltransferase activity
GGD92_RS15545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GGD92_RS15550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GGD92_RS15555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GGD92_RS15560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GGD92_RS15565	COG0195	Participates in both transcription termination and antitermination
GGD92_RS15585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGD92_RS15590	COG0149	triose-phosphate isomerase activity
GGD92_RS15595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGD92_RS15600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GGD92_RS15610	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GGD92_RS15625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGD92_RS15630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GGD92_RS15635	COG0505	Belongs to the CarA family
GGD92_RS15640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GGD92_RS15645	COG0484	heat shock protein binding
GGD92_RS15650	COG0443	Heat shock 70 kDa protein
GGD92_RS15655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GGD92_RS15660	COG0497	DNA recombination
GGD92_RS15665	COG0735	belongs to the Fur family
GGD92_RS15670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGD92_RS15675	COG2914	Belongs to the UPF0125 (RnfH) family
GGD92_RS15685	COG0733	neurotransmitter:sodium symporter activity
GGD92_RS15690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GGD92_RS15695	COG2186	Transcriptional regulator
GGD92_RS15700	COG1620	l-lactate permease
GGD92_RS15705	COG0247	lactate metabolic process
GGD92_RS15735	COG0582	viral genome integration into host DNA
GGD92_RS15855	COG0697	spore germination
GGD92_RS15890	COG1733	regulation of RNA biosynthetic process
GGD92_RS15945	COG0840	transmembrane signaling receptor activity
GGD92_RS15960	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GGD92_RS15970	COG2610	gluconate transmembrane transporter activity
GGD92_RS15975	COG0659	secondary active sulfate transmembrane transporter activity
GGD92_RS15985	COG0583	DNA-binding transcription factor activity
GGD92_RS15990	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGD92_RS16005	COG0583	DNA-binding transcription factor activity
GGD92_RS16010	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGD92_RS16020	COG1113	amino acid transport
GGD92_RS16030	COG1522	sequence-specific DNA binding
GGD92_RS16040	COG4638	Rieske (2fe-2S)
GGD92_RS16045	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GGD92_RS16050	COG0543	2 iron, 2 sulfur cluster binding
GGD92_RS16050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGD92_RS16055	COG1113	amino acid transport
GGD92_RS16060	COG3135	benzoate transporter
GGD92_RS16070	COG3483	tryptophan 2,3-dioxygenase activity
GGD92_RS16075	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GGD92_RS16115	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGD92_RS16135	COG3617	BRO family, N-terminal domain
GGD92_RS16180	COG2885	chlorophyll binding
GGD92_RS16185	COG2199	diguanylate cyclase activity
GGD92_RS16195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGD92_RS16200	COG1074	ATP-dependent DNA helicase activity
GGD92_RS16205	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GGD92_RS16250	COG2233	PERMEase
GGD92_RS16255	COG1309	transcriptional regulator
GGD92_RS16260	COG1739	Uncharacterized protein family UPF0029
GGD92_RS16265	COG3845	ABC transporter
GGD92_RS16270	COG4603	Belongs to the binding-protein-dependent transport system permease family
GGD92_RS16275	COG1079	Belongs to the binding-protein-dependent transport system permease family
GGD92_RS16300	COG0387	Pfam Sodium calcium exchanger
GGD92_RS16315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGD92_RS16320	COG0477	Major facilitator Superfamily
GGD92_RS16325	COG0583	DNA-binding transcription factor activity
GGD92_RS16330	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GGD92_RS16335	COG0604	alcohol dehydrogenase
GGD92_RS16360	COG2217	Heavy metal translocating P-type atpase
GGD92_RS16375	COG0840	transmembrane signaling receptor activity
GGD92_RS16385	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS16485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGD92_RS16500	COG0534	Mate efflux family protein
GGD92_RS16510	COG1166	arginine decarboxylase activity
GGD92_RS16515	COG0023	Translation Initiation Factor
GGD92_RS16540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GGD92_RS16555	COG2264	protein methyltransferase activity
GGD92_RS16565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGD92_RS16575	COG0138	bifunctional purine biosynthesis protein purh
GGD92_RS16580	COG0151	Belongs to the GarS family
GGD92_RS16590	COG2095	MarC family integral membrane protein
GGD92_RS16625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGD92_RS16635	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GGD92_RS16645	COG3657	addiction module killer protein
GGD92_RS16650	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGD92_RS16695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGD92_RS16705	COG0683	leucine binding
GGD92_RS16720	COG0411	ABC transporter
GGD92_RS16730	COG0829	nickel cation binding
GGD92_RS16735	COG0831	urea catabolic process
GGD92_RS16750	COG0832	Belongs to the urease beta subunit family
GGD92_RS16755	COG0804	urea catabolic process
GGD92_RS16765	COG0789	Transcriptional regulator
GGD92_RS16770	COG0484	heat shock protein binding
GGD92_RS16775	COG0443	Heat shock 70 kDa protein
GGD92_RS16810	COG0697	spore germination
GGD92_RS16815	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GGD92_RS16820	COG2076	Multidrug Resistance protein
GGD92_RS16825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGD92_RS16830	COG0583	DNA-binding transcription factor activity
GGD92_RS16840	COG2982	Protein involved in outer membrane biogenesis
GGD92_RS16855	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GGD92_RS16860	COG0830	nickel cation binding
GGD92_RS16865	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GGD92_RS16885	COG4221	oxidoreductase activity
GGD92_RS16915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS16920	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS16925	COG0583	DNA-binding transcription factor activity
GGD92_RS16930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GGD92_RS16935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GGD92_RS16960	COG2307	Protein conserved in bacteria
GGD92_RS16960	COG2308	Evidence 4 Homologs of previously reported genes of
GGD92_RS16980	COG1032	radical SAM domain protein
GGD92_RS16985	COG0305	Participates in initiation and elongation during chromosome replication
GGD92_RS16990	COG0359	binds to the 23S rRNA
GGD92_RS17000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GGD92_RS17005	COG0360	Binds together with S18 to 16S ribosomal RNA
GGD92_RS17010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGD92_RS17015	COG0557	exoribonuclease II activity
GGD92_RS17035	COG1178	ABC-type Fe3 transport system permease component
GGD92_RS17045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GGD92_RS17050	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GGD92_RS17055	COG0330	HflC and HflK could
GGD92_RS17060	COG0330	HflC and HflK could
GGD92_RS17065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGD92_RS17070	COG1923	regulation of RNA biosynthetic process
GGD92_RS17075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GGD92_RS17080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GGD92_RS17085	COG0860	N-Acetylmuramoyl-L-alanine amidase
GGD92_RS17090	COG0802	atpase or kinase
GGD92_RS17095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGD92_RS17095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGD92_RS17105	COG2860	membrane
GGD92_RS17110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GGD92_RS17115	COG1162	GTPase activity
GGD92_RS17125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGD92_RS17140	COG0688	phosphatidylethanolamine metabolic process
GGD92_RS17145	COG0560	Phosphoserine phosphatase
GGD92_RS17145	COG3830	Belongs to the UPF0237 family
GGD92_RS17180	COG3150	esterase
GGD92_RS17185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GGD92_RS17195	COG0494	nUDIX hydrolase
GGD92_RS17210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GGD92_RS17215	COG1538	Outer membrane efflux protein
GGD92_RS17220	COG1519	Transferase
GGD92_RS17240	COG0667	Aldo Keto reductase
GGD92_RS17250	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GGD92_RS17250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GGD92_RS17265	COG1132	(ABC) transporter
GGD92_RS17280	COG1216	Glycosyl transferase, family 2
GGD92_RS17285	COG2192	nodulation
GGD92_RS17300	COG3642	lipopolysaccharide core region biosynthetic process
GGD92_RS17310	COG0438	transferase activity, transferring glycosyl groups
GGD92_RS17315	COG0859	PFAM glycosyl transferase family 9
GGD92_RS17320	COG0859	PFAM glycosyl transferase family 9
GGD92_RS17325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GGD92_RS17345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGD92_RS17350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GGD92_RS17360	COG3192	ethanolamine utilization protein
GGD92_RS17370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS17375	COG0493	'glutamate synthase
GGD92_RS17380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGD92_RS17385	COG2873	o-acetylhomoserine
GGD92_RS17395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGD92_RS17400	COG0506	proline dehydrogenase activity
GGD92_RS17400	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GGD92_RS17400	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GGD92_RS17405	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS17410	COG0840	transmembrane signaling receptor activity
GGD92_RS17435	COG3263	regulation of cellular component size
GGD92_RS17440	COG3264	Mechanosensitive ion channel
GGD92_RS17440	COG1196	nuclear chromosome segregation
GGD92_RS17445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GGD92_RS17460	COG3118	belongs to the thioredoxin family
GGD92_RS17465	COG1192	Involved in chromosome partitioning
GGD92_RS17480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GGD92_RS17485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GGD92_RS17510	COG2986	histidine ammonia-lyase
GGD92_RS17550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGD92_RS17560	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS17565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGD92_RS17580	COG0583	DNA-binding transcription factor activity
GGD92_RS17585	COG2814	Major facilitator Superfamily
GGD92_RS17590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GGD92_RS17595	COG0493	'glutamate synthase
GGD92_RS17600	COG0069	glutamate synthase activity
GGD92_RS17600	COG0067	glutamate synthase
GGD92_RS17600	COG0070	glutamate synthase
GGD92_RS17610	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GGD92_RS17615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GGD92_RS17650	COG0281	malic enzyme
GGD92_RS17660	COG0254	rRNA binding
GGD92_RS17665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGD92_RS17670	COG0018	arginyl-trna synthetase
GGD92_RS17680	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GGD92_RS17685	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GGD92_RS17710	COG1309	transcriptional regulator
GGD92_RS17730	COG2226	methyltransferase
GGD92_RS17740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GGD92_RS17745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GGD92_RS17750	COG0140	phosphoribosyl-ATP diphosphatase activity
GGD92_RS17755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GGD92_RS17760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GGD92_RS17775	COG0840	transmembrane signaling receptor activity
GGD92_RS17780	COG1126	abc transporter atp-binding protein
GGD92_RS17785	COG0765	amino acid transport
GGD92_RS17795	COG2943	transferase activity, transferring hexosyl groups
GGD92_RS17800	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GGD92_RS17805	COG1490	D-aminoacyl-tRNA deacylase activity
GGD92_RS17820	COG1228	amidohydrolase
GGD92_RS17830	COG2986	histidine ammonia-lyase
GGD92_RS17835	COG2986	histidine ammonia-lyase
GGD92_RS17840	COG4175	Glycine betaine
GGD92_RS17845	COG4176	ABC-type proline glycine betaine transport system permease component
GGD92_RS17855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGD92_RS17860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GGD92_RS17870	COG2188	Transcriptional regulator
GGD92_RS17875	COG0402	S-adenosylhomocysteine deaminase activity
GGD92_RS17915	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GGD92_RS17930	COG0058	SHG alpha-glucan phosphorylase activity
GGD92_RS17940	COG1217	gtp-binding protein TYPA
GGD92_RS17945	COG0301	tRNA thio-modification
GGD92_RS17945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGD92_RS17965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GGD92_RS17970	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS17975	COG0583	DNA-binding transcription factor activity
GGD92_RS17980	COG0477	Major facilitator Superfamily
GGD92_RS17990	COG3852	Histidine kinase
GGD92_RS18005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GGD92_RS18010	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GGD92_RS18025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGD92_RS18035	COG4942	peptidase
GGD92_RS18040	COG0793	Belongs to the peptidase S41A family
GGD92_RS18045	COG2861	carbohydrate metabolic process
GGD92_RS18055	COG0107	imidazoleglycerol-phosphate synthase activity
GGD92_RS18060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GGD92_RS18070	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GGD92_RS18075	COG0131	Imidazoleglycerol-phosphate dehydratase
GGD92_RS18080	COG2223	nitrite transmembrane transporter activity
GGD92_RS18090	COG1194	a g-specific adenine glycosylase
GGD92_RS18095	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GGD92_RS18160	COG4215	(ABC) transporter
GGD92_RS18180	COG1473	amidohydrolase
GGD92_RS18185	COG0583	DNA-binding transcription factor activity
GGD92_RS18190	COG3842	ATPase activity
GGD92_RS18205	COG1177	transmembrane transport
GGD92_RS18220	COG3383	formate dehydrogenase (NAD+) activity
GGD92_RS18280	COG2957	Belongs to the agmatine deiminase family
GGD92_RS18290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGD92_RS18295	COG1088	dTDP-glucose 4,6-dehydratase activity
GGD92_RS18310	COG1091	dTDP-4-dehydrorhamnose reductase activity
GGD92_RS18330	COG1218	3'(2'),5'-bisphosphate nucleotidase
GGD92_RS18335	COG0494	nUDIX hydrolase
GGD92_RS18340	COG1011	Hydrolase
GGD92_RS18345	COG1652	LysM domain
GGD92_RS18350	COG0583	DNA-binding transcription factor activity
GGD92_RS18365	COG0824	Thioesterase
GGD92_RS18370	COG0514	ATP-dependent DNA helicase (RecQ)
GGD92_RS18410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GGD92_RS18415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GGD92_RS18425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GGD92_RS18430	COG2203	Gaf domain
GGD92_RS18430	COG2200	EAL domain
GGD92_RS18430	COG2199	diguanylate cyclase activity
GGD92_RS18435	COG4067	protein conserved in archaea
GGD92_RS18435	COG0189	ligase activity
GGD92_RS18440	COG0189	ligase activity
GGD92_RS18445	COG2205	protein histidine kinase activity
GGD92_RS18455	COG2183	response to ionizing radiation
GGD92_RS18465	COG2918	glutathione biosynthetic process
GGD92_RS18470	COG4521	taurine ABC transporter
GGD92_RS18475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GGD92_RS18480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGD92_RS18485	COG2175	clavaminate synthase activity
GGD92_RS18515	COG0667	Aldo Keto reductase
GGD92_RS18520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGD92_RS18530	COG1609	Transcriptional regulator
GGD92_RS18550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGD92_RS18555	COG1045	serine acetyltransferase
GGD92_RS18560	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GGD92_RS18565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS18570	COG0765	amino acid transport
GGD92_RS18575	COG1126	abc transporter atp-binding protein
GGD92_RS18595	COG1464	Belongs to the NlpA lipoprotein family
GGD92_RS18600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGD92_RS18605	COG2011	ABC-type metal ion transport system permease component
GGD92_RS18615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGD92_RS18635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS18640	COG1126	abc transporter atp-binding protein
GGD92_RS18645	COG0765	amino acid transport
GGD92_RS18650	COG0765	amino acid transport
GGD92_RS18690	COG0583	DNA-binding transcription factor activity
GGD92_RS18695	COG0590	tRNA wobble adenosine to inosine editing
GGD92_RS18700	COG2807	transmembrane transport
GGD92_RS18715	COG3550	peptidyl-serine autophosphorylation
GGD92_RS18730	COG3655	Transcriptional regulator
GGD92_RS18755	COG4771	TonB-dependent receptor
GGD92_RS18790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGD92_RS18795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGD92_RS18830	COG3550	peptidyl-serine autophosphorylation
GGD92_RS18865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GGD92_RS18870	COG4208	sulfate ABC transporter
GGD92_RS18875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GGD92_RS18880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GGD92_RS18900	COG2199	diguanylate cyclase activity
GGD92_RS18910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGD92_RS18915	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS18975	COG1595	DNA-templated transcription, initiation
GGD92_RS18980	COG2304	oxidoreductase activity
GGD92_RS19015	COG1215	transferase activity, transferring glycosyl groups
GGD92_RS19020	COG1649	PFAM Uncharacterised BCR, COG1649
GGD92_RS19020	COG0726	polysaccharide deacetylase
GGD92_RS19025	COG0457	Tetratricopeptide repeat
GGD92_RS19030	COG5339	Protein conserved in bacteria
GGD92_RS19045	COG1566	PFAM secretion protein HlyD family protein
GGD92_RS19055	COG1289	transmembrane transporter activity
GGD92_RS19065	COG2026	Addiction module toxin, RelE StbE family
GGD92_RS19110	COG1595	DNA-templated transcription, initiation
GGD92_RS19135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGD92_RS19150	COG2175	clavaminate synthase activity
GGD92_RS19155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS19160	COG2274	protein secretion by the type I secretion system
GGD92_RS19165	COG1538	Outer membrane efflux protein
GGD92_RS19180	COG3300	MHYT domain
GGD92_RS19180	COG5001	Diguanylate cyclase
GGD92_RS19195	COG0840	transmembrane signaling receptor activity
GGD92_RS19235	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS19240	COG0583	DNA-binding transcription factor activity
GGD92_RS19260	COG0427	acetyl-CoA hydrolase
GGD92_RS19300	COG2851	Citrate transporter
GGD92_RS19305	COG0861	Integral membrane protein TerC family
GGD92_RS19310	COG1283	sodium-dependent phosphate transmembrane transporter activity
GGD92_RS19315	COG0612	Peptidase, M16
GGD92_RS19325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GGD92_RS19330	COG1127	ABC transporter
GGD92_RS19345	COG0700	Nucleoside recognition
GGD92_RS19350	COG1301	dicarboxylic acid transport
GGD92_RS19370	COG2204	response regulator
GGD92_RS19375	COG5002	protein histidine kinase activity
GGD92_RS19380	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GGD92_RS19385	COG3023	N-Acetylmuramoyl-L-alanine amidase
GGD92_RS19400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGD92_RS19410	COG3245	cytochrome
GGD92_RS19415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GGD92_RS19435	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GGD92_RS19440	COG0735	belongs to the Fur family
GGD92_RS19445	COG1121	(ABC) transporter
GGD92_RS19450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGD92_RS19465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGD92_RS19470	COG2011	ABC-type metal ion transport system permease component
GGD92_RS19485	COG0109	protoheme IX farnesyltransferase activity
GGD92_RS19515	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GGD92_RS19520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGD92_RS19525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGD92_RS19570	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GGD92_RS19575	COG0339	signal peptide processing
GGD92_RS19580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGD92_RS19605	COG1764	response to oxidative stress
GGD92_RS19610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGD92_RS19620	COG3360	Dodecin
GGD92_RS19635	COG0133	tryptophan synthase activity
GGD92_RS19640	COG0159	tryptophan synthase activity
GGD92_RS19660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GGD92_RS19670	COG0583	DNA-binding transcription factor activity
GGD92_RS19675	COG3119	arylsulfatase activity
GGD92_RS19690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GGD92_RS19695	COG0408	coproporphyrinogen oxidase activity
GGD92_RS19705	COG0009	L-threonylcarbamoyladenylate synthase
GGD92_RS19710	COG0758	DNA mediated transformation
GGD92_RS19715	COG0242	peptide deformylase activity
GGD92_RS19720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GGD92_RS19725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGD92_RS19730	COG0569	domain protein
GGD92_RS19750	COG2818	Glycosylase
GGD92_RS19755	COG0752	glycyl-tRNA synthetase alpha subunit
GGD92_RS19760	COG0751	glycine-tRNA ligase activity
GGD92_RS19775	COG5002	protein histidine kinase activity
GGD92_RS19790	COG0745	RESPONSE REGULATOR receiver
GGD92_RS19820	COG0187	DNA topoisomerase II activity
GGD92_RS19825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GGD92_RS19830	COG0592	DNA-directed DNA polymerase activity
GGD92_RS19835	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GGD92_RS19840	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GGD92_RS19845	COG0594	ribonuclease P activity
GGD92_RS19850	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GGD92_RS19855	COG0706	membrane insertase activity
GGD92_RS19860	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GGD92_RS19870	COG1113	amino acid transport
GGD92_RS19875	COG5285	phytanoyl-CoA dioxygenase
GGD92_RS19885	COG0445	tRNA wobble uridine modification
GGD92_RS19890	COG0357	Ribosomal RNA small subunit methyltransferase G
GGD92_RS19895	COG1192	Involved in chromosome partitioning
GGD92_RS19900	COG1475	DNA binding
GGD92_RS19905	COG3312	ion transport
GGD92_RS19910	COG0356	it plays a direct role in the translocation of protons across the membrane
GGD92_RS19920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GGD92_RS19925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGD92_RS19930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GGD92_RS19935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GGD92_RS19940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GGD92_RS19945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GGD92_RS19950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGD92_RS19955	COG1349	DNA-binding transcription factor activity
GGD92_RS19960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GGD92_RS20040	COG1116	anion transmembrane transporter activity
GGD92_RS20045	COG0583	DNA-binding transcription factor activity
GGD92_RS20050	COG0625	glutathione transferase activity
GGD92_RS20055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGD92_RS20055	COG1017	nitric oxide dioxygenase activity
GGD92_RS20070	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS20075	COG1522	sequence-specific DNA binding
GGD92_RS20080	COG4589	Belongs to the CDS family
GGD92_RS20095	COG0671	phosphoesterase, PA-phosphatase related
GGD92_RS20095	COG2453	phosphatase
GGD92_RS20100	COG2267	carboxylic ester hydrolase activity
GGD92_RS20105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGD92_RS20115	COG0330	HflC and HflK could
GGD92_RS20145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGD92_RS20150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGD92_RS20160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GGD92_RS20170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GGD92_RS20175	COG0803	Belongs to the bacterial solute-binding protein 9 family
GGD92_RS20180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGD92_RS20190	COG1469	GTP cyclohydrolase I activity
GGD92_RS20195	COG0860	N-Acetylmuramoyl-L-alanine amidase
GGD92_RS20220	COG0523	cobalamin synthesis protein
GGD92_RS20230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GGD92_RS20235	COG0531	amino acid
GGD92_RS20240	COG1607	acyl-coa hydrolase
GGD92_RS20245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGD92_RS20245	COG4651	solute:proton antiporter activity
GGD92_RS20265	COG0210	DNA helicase
GGD92_RS20285	COG0583	DNA-binding transcription factor activity
GGD92_RS20290	COG0439	Biotin carboxylase
GGD92_RS20295	COG0511	ligase activity, forming carbon-carbon bonds
GGD92_RS20295	COG5016	pyruvate
GGD92_RS20310	COG0765	amino acid transport
GGD92_RS20315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS20345	COG2391	methyltransferase activity
GGD92_RS20375	COG0252	asparaginase activity
GGD92_RS20380	COG1115	amino acid carrier protein
GGD92_RS20410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GGD92_RS20415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGD92_RS20440	COG1027	Aspartate ammonia-lyase
GGD92_RS20445	COG0583	DNA-binding transcription factor activity
GGD92_RS20475	COG1607	acyl-coa hydrolase
GGD92_RS20495	COG0573	inorganic phosphate transmembrane transporter activity
GGD92_RS20500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGD92_RS20505	COG0704	Plays a role in the regulation of phosphate uptake
GGD92_RS20525	COG0739	heme binding
GGD92_RS20530	COG1253	flavin adenine dinucleotide binding
GGD92_RS20550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GGD92_RS20555	COG3161	chorismate lyase activity
GGD92_RS20720	COG2815	serine threonine protein kinase
GGD92_RS20720	COG0515	serine threonine protein kinase
GGD92_RS20725	COG0577	efflux transmembrane transporter activity
GGD92_RS20725	COG1136	(ABC) transporter
GGD92_RS20755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GGD92_RS20760	COG0583	DNA-binding transcription factor activity
GGD92_RS20770	COG0848	biopolymer transport protein
GGD92_RS20795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGD92_RS20800	COG1758	RNA polymerase activity
GGD92_RS20805	COG0194	GDP metabolic process
GGD92_RS20810	COG1561	YicC-like family, N-terminal region
GGD92_RS20815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GGD92_RS20825	COG0708	Exodeoxyribonuclease III
GGD92_RS20830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GGD92_RS20835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GGD92_RS20840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGD92_RS20845	COG0756	dUTP diphosphatase activity
GGD92_RS20850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGD92_RS20855	COG2003	Belongs to the UPF0758 family
GGD92_RS20860	COG0747	negative chemotaxis
GGD92_RS20865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GGD92_RS20870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GGD92_RS20880	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS20890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGD92_RS20895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS20905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS20920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS20925	COG0251	oxidation-reduction process
GGD92_RS20930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GGD92_RS20945	COG0427	acetyl-CoA hydrolase
GGD92_RS20950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGD92_RS20965	COG0534	Mate efflux family protein
GGD92_RS20970	COG0583	DNA-binding transcription factor activity
GGD92_RS20995	COG0606	chelatase, subunit chli
GGD92_RS21005	COG0347	Belongs to the P(II) protein family
GGD92_RS21010	COG0004	ammonium transporteR
GGD92_RS21015	COG0432	Pfam Uncharacterised protein family UPF0047
GGD92_RS21025	COG1011	Hydrolase
GGD92_RS21030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GGD92_RS21040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGD92_RS21045	COG0019	diaminopimelate decarboxylase activity
GGD92_RS21055	COG1965	Belongs to the frataxin family
GGD92_RS21065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGD92_RS21085	COG0625	glutathione transferase activity
GGD92_RS21090	COG0165	Argininosuccinate lyase
GGD92_RS21100	COG0181	hydroxymethylbilane synthase activity
GGD92_RS21120	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GGD92_RS21145	COG0488	(ABC) transporter
GGD92_RS21155	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS21185	COG0672	)-iron permease
GGD92_RS21190	COG1671	Belongs to the UPF0178 family
GGD92_RS21195	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GGD92_RS21200	COG0586	Pfam SNARE associated Golgi protein
GGD92_RS21210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GGD92_RS21215	COG0248	Ppx GppA phosphatase
GGD92_RS21220	COG1126	abc transporter atp-binding protein
GGD92_RS21225	COG0765	amino acid transport
GGD92_RS21230	COG0765	amino acid transport
GGD92_RS21235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS21240	COG2186	Transcriptional regulator
GGD92_RS21255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GGD92_RS21280	COG0842	Transport permease protein
GGD92_RS21285	COG0842	Transport permease protein
GGD92_RS21285	COG1129	ABC transporter
GGD92_RS21290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS21305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGD92_RS21325	COG3079	Belongs to the UPF0149 family
GGD92_RS21330	COG0006	proline dipeptidase activity
GGD92_RS21335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGD92_RS21345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGD92_RS21355	COG1178	ABC-type Fe3 transport system permease component
GGD92_RS21360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GGD92_RS21365	COG0509	glycine decarboxylation via glycine cleavage system
GGD92_RS21370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGD92_RS21375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GGD92_RS21375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GGD92_RS21390	COG3424	synthase
GGD92_RS21410	COG1309	transcriptional regulator
GGD92_RS21420	COG1309	transcriptional regulator
GGD92_RS21430	COG1585	Membrane protein implicated in regulation of membrane protease activity
GGD92_RS21435	COG0330	HflC and HflK could
GGD92_RS21445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGD92_RS21455	COG1522	sequence-specific DNA binding
GGD92_RS21470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GGD92_RS21470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GGD92_RS21480	COG0450	alkyl hydroperoxide reductase
GGD92_RS21485	COG0431	NADPH-dependent FMN reductase
GGD92_RS21490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGD92_RS21495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGD92_RS21500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGD92_RS21505	COG1116	anion transmembrane transporter activity
GGD92_RS21515	COG1072	(Pantothenic acid kinase))
GGD92_RS21525	COG0174	glutamine synthetase
GGD92_RS21530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GGD92_RS21535	COG0174	glutamine synthetase
GGD92_RS21555	COG3842	ATPase activity
GGD92_RS21560	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGD92_RS21565	COG1177	transmembrane transport
GGD92_RS21595	COG1683	Conserved Protein
GGD92_RS21600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS21610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGD92_RS21615	COG0277	FAD linked oxidase domain protein
GGD92_RS21620	COG0179	Fumarylacetoacetate (FAA) hydrolase
GGD92_RS21625	COG3204	pilus organization
GGD92_RS21630	COG3204	pilus organization
GGD92_RS21635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GGD92_RS21640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GGD92_RS21650	COG0702	epimerase
GGD92_RS21665	COG0494	nUDIX hydrolase
GGD92_RS21670	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GGD92_RS21680	COG0730	response to heat
GGD92_RS21685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GGD92_RS21690	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGD92_RS21715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGD92_RS21845	COG0038	chloride channel
GGD92_RS21870	COG0148	phosphopyruvate hydratase activity
GGD92_RS21875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GGD92_RS21885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GGD92_RS21895	COG0589	response to stress
GGD92_RS21900	COG0659	secondary active sulfate transmembrane transporter activity
GGD92_RS21910	COG2072	flavoprotein involved in K transport
GGD92_RS21920	COG0431	NADPH-dependent FMN reductase
GGD92_RS21925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGD92_RS21930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GGD92_RS21935	COG0640	Transcriptional regulator
GGD92_RS22030	COG0671	phosphoesterase, PA-phosphatase related
GGD92_RS22035	COG0789	Transcriptional regulator
GGD92_RS22045	COG0583	DNA-binding transcription factor activity
GGD92_RS22050	COG3842	ATPase activity
GGD92_RS22055	COG1178	ABC-type Fe3 transport system permease component
GGD92_RS22060	COG1840	ABC-type Fe3 transport system, periplasmic component
GGD92_RS22075	COG1160	GTP binding
GGD92_RS22090	COG1823	symporter activity
GGD92_RS22115	COG0129	dihydroxy-acid dehydratase activity
GGD92_RS22130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGD92_RS22140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GGD92_RS22145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGD92_RS22150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GGD92_RS22155	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GGD92_RS22185	COG0429	hydrolase of the alpha beta-hydrolase fold
GGD92_RS22190	COG0742	ribosomal rna small subunit methyltransferase
GGD92_RS22195	COG0612	Peptidase, M16
GGD92_RS22200	COG0612	Peptidase, M16
GGD92_RS22205	COG0552	protein localization to endoplasmic reticulum
GGD92_RS22210	COG2884	Cell division ATP-binding protein ftsE
GGD92_RS22215	COG2177	Part of the ABC transporter FtsEX involved in
GGD92_RS22225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGD92_RS22230	COG2363	Small membrane protein
GGD92_RS22240	COG2022	thiamine diphosphate biosynthetic process
GGD92_RS22245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GGD92_RS22250	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GGD92_RS22260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGD92_RS22265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GGD92_RS22275	COG2813	Specifically methylates the guanine in position
GGD92_RS22275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGD92_RS22280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGD92_RS22285	COG1872	DUF167
GGD92_RS22310	COG0791	NLP P60 protein
GGD92_RS22320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GGD92_RS22325	COG0540	Belongs to the ATCase OTCase family
GGD92_RS22330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GGD92_RS22335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GGD92_RS22340	COG1678	Uncharacterized ACR, COG1678
GGD92_RS22350	COG0189	ligase activity
GGD92_RS22375	COG2198	Histidine kinase
GGD92_RS22375	COG0784	Response regulator, receiver
GGD92_RS22375	COG0643	Histidine kinase
GGD92_RS22440	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GGD92_RS22445	COG3052	prosthetic group binding
GGD92_RS22465	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GGD92_RS22485	COG1272	protein, Hemolysin III
GGD92_RS22505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS22510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GGD92_RS22520	COG3038	cytochrome b561
GGD92_RS22525	COG2353	YceI-like domain
GGD92_RS22530	COG0513	Belongs to the DEAD box helicase family
GGD92_RS22540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GGD92_RS22545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GGD92_RS22555	COG2116	formate transmembrane transporter activity
GGD92_RS22585	COG1422	Protein of unknown function (DUF1090)
GGD92_RS22590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GGD92_RS22595	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GGD92_RS22610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGD92_RS22615	COG0126	phosphoglycerate kinase activity
GGD92_RS22645	COG1451	nucleotide metabolic process
GGD92_RS22655	COG2153	protein acetylation
GGD92_RS22665	COG1289	transmembrane transporter activity
GGD92_RS22670	COG2081	HI0933 family
GGD92_RS22675	COG0513	Belongs to the DEAD box helicase family
GGD92_RS22680	COG0477	Major facilitator Superfamily
GGD92_RS22685	COG0312	modulator of DNA gyrase
GGD92_RS22695	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GGD92_RS22700	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS22705	COG1309	transcriptional regulator
GGD92_RS22710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGD92_RS22715	COG4175	Glycine betaine
GGD92_RS22720	COG4176	ABC-type proline glycine betaine transport system permease component
GGD92_RS22730	COG1760	l-serine dehydratase
GGD92_RS22775	COG1250	3-hydroxyacyl-CoA dehydrogenase
GGD92_RS22780	COG3246	L-lysine catabolic process to acetate
GGD92_RS22805	COG0583	DNA-binding transcription factor activity
GGD92_RS22810	COG2233	PERMEase
GGD92_RS22840	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS22840	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGD92_RS22845	COG0247	lactate metabolic process
GGD92_RS22845	COG2181	nitrate reductase activity
GGD92_RS22850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GGD92_RS22865	COG1858	cytochrome C peroxidase
GGD92_RS22875	COG4638	Rieske (2fe-2S)
GGD92_RS22880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGD92_RS22880	COG1017	nitric oxide dioxygenase activity
GGD92_RS22885	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GGD92_RS22890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGD92_RS22905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGD92_RS22935	COG1063	alcohol dehydrogenase
GGD92_RS22950	COG3041	Addiction module toxin RelE StbE family
GGD92_RS22965	COG1595	DNA-templated transcription, initiation
GGD92_RS22975	COG3766	membrane
GGD92_RS22985	COG0754	glutathionylspermidine amidase activity
GGD92_RS22990	COG0204	Acyl-transferase
GGD92_RS22995	COG4067	protein conserved in archaea
GGD92_RS22995	COG0189	ligase activity
GGD92_RS23000	COG0745	RESPONSE REGULATOR receiver
GGD92_RS23005	COG2205	protein histidine kinase activity
GGD92_RS23010	COG4452	Inner membrane protein CreD
GGD92_RS23020	COG0625	glutathione transferase activity
GGD92_RS23040	COG4774	siderophore transport
GGD92_RS23045	COG3712	iron ion homeostasis
GGD92_RS23050	COG1595	DNA-templated transcription, initiation
GGD92_RS23065	COG2204	response regulator
GGD92_RS23070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGD92_RS23085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GGD92_RS23095	COG3585	molybdate ion transport
GGD92_RS23095	COG2005	Transcriptional regulator
GGD92_RS23100	COG1040	competence protein
GGD92_RS23105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GGD92_RS23110	COG0156	8-amino-7-oxononanoate synthase activity
GGD92_RS23115	COG2226	methyltransferase
GGD92_RS23115	COG1073	alpha beta
GGD92_RS23135	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS23140	COG3706	GGDEF domain
GGD92_RS23145	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS23150	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS23155	COG0583	DNA-binding transcription factor activity
GGD92_RS23160	COG2258	MOSC domain
GGD92_RS23165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGD92_RS23180	COG0535	radical SAM domain protein
GGD92_RS23190	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GGD92_RS23195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GGD92_RS23205	COG1025	Belongs to the peptidase M16 family
GGD92_RS23210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGD92_RS23240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGD92_RS23245	COG0358	DNA primase activity
GGD92_RS23250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GGD92_RS23255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GGD92_RS23260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GGD92_RS23265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGD92_RS23275	COG0617	tRNA 3'-terminal CCA addition
GGD92_RS23280	COG2719	SpoVR family
GGD92_RS23285	COG2718	Belongs to the UPF0229 family
GGD92_RS23290	COG2766	serine protein kinase
GGD92_RS23295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGD92_RS23300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GGD92_RS23305	COG2967	ApaG domain
GGD92_RS23310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GGD92_RS23315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GGD92_RS23320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGD92_RS23325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GGD92_RS23330	COG3178	'Phosphotransferase
GGD92_RS23335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GGD92_RS23340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GGD92_RS23355	COG2197	response regulator
GGD92_RS23360	COG3842	ATPase activity
GGD92_RS23370	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGD92_RS23380	COG1454	alcohol dehydrogenase
GGD92_RS23390	COG0546	phosphoglycolate phosphatase activity
GGD92_RS23400	COG0512	Glutamine amidotransferase of anthranilate synthase
GGD92_RS23405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGD92_RS23410	COG0134	indole-3-glycerol-phosphate synthase activity
GGD92_RS23425	COG1765	OsmC-like protein
GGD92_RS23430	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GGD92_RS23435	COG0537	adenosine 5'-monophosphoramidase activity
GGD92_RS23440	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS23455	COG1981	membrane
GGD92_RS23460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GGD92_RS23465	COG0316	Belongs to the HesB IscA family
GGD92_RS23470	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GGD92_RS23475	COG0739	heme binding
GGD92_RS23480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GGD92_RS23535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGD92_RS23555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GGD92_RS23560	COG0081	regulation of translation
GGD92_RS23565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GGD92_RS23570	COG0222	ribosome binding
GGD92_RS23575	COG0085	RNA polymerase activity
GGD92_RS23580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GGD92_RS23585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GGD92_RS23590	COG0049	tRNA binding
GGD92_RS23595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGD92_RS23600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGD92_RS23605	COG0051	transcription antitermination factor activity, RNA binding
GGD92_RS23610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GGD92_RS23615	COG0088	Forms part of the polypeptide exit tunnel
GGD92_RS23620	COG0089	rRNA binding
GGD92_RS23625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GGD92_RS23630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GGD92_RS23635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GGD92_RS23640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GGD92_RS23645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GGD92_RS23650	COG0255	Belongs to the universal ribosomal protein uL29 family
GGD92_RS23655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GGD92_RS23660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GGD92_RS23665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GGD92_RS23670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GGD92_RS23675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GGD92_RS23680	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GGD92_RS23685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GGD92_RS23690	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GGD92_RS23695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GGD92_RS23700	COG1841	ribosomal large subunit assembly
GGD92_RS23705	COG0200	Binds to the 23S rRNA
GGD92_RS23715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GGD92_RS23720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGD92_RS23725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GGD92_RS23730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GGD92_RS23735	COG0202	RNA polymerase activity
GGD92_RS23740	COG0203	ribosomal protein L17
GGD92_RS23750	COG2193	ferroxidase activity
GGD92_RS23755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GGD92_RS23760	COG2814	Major facilitator Superfamily
GGD92_RS23765	COG0629	single-stranded DNA binding
GGD92_RS23830	COG1335	isochorismatase
GGD92_RS23835	COG4753	response regulator
GGD92_RS23835	COG2207	Transcriptional regulator
GGD92_RS23840	COG1201	RNA secondary structure unwinding
GGD92_RS23855	COG3047	cAMP biosynthetic process
GGD92_RS23885	COG3118	belongs to the thioredoxin family
GGD92_RS23890	COG2264	protein methyltransferase activity
GGD92_RS23900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGD92_RS23905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGD92_RS23905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGD92_RS23920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GGD92_RS23925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGD92_RS23930	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GGD92_RS23935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GGD92_RS23945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGD92_RS23960	COG4206	TonB-dependent receptor
GGD92_RS23965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GGD92_RS23970	COG0142	geranyltranstransferase activity
GGD92_RS23975	COG1722	exodeoxyribonuclease VII activity
GGD92_RS23985	COG0583	DNA-binding transcription factor activity
GGD92_RS24000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGD92_RS24005	COG4676	Protein conserved in bacteria
GGD92_RS24010	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
GGD92_RS24025	COG5445	Predicted secreted protein (DUF2300)
GGD92_RS24030	COG4676	Protein conserved in bacteria
GGD92_RS24055	COG3706	GGDEF domain
GGD92_RS24065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GGD92_RS24070	COG3228	Belongs to the MtfA family
GGD92_RS24075	COG0586	Pfam SNARE associated Golgi protein
GGD92_RS24080	COG0456	acetyltransferase
GGD92_RS24085	COG4302	ethanolamine ammonia-lyase activity
GGD92_RS24090	COG4303	Ethanolamine ammonia lyase large subunit
GGD92_RS24095	COG4303	Ethanolamine ammonia lyase large subunit
GGD92_RS24115	COG3284	Transcriptional regulator
GGD92_RS24120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GGD92_RS24135	COG0702	epimerase
GGD92_RS24155	COG1346	cytolysis
GGD92_RS24165	COG0586	Pfam SNARE associated Golgi protein
GGD92_RS24170	COG2094	Belongs to the DNA glycosylase MPG family
GGD92_RS24175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GGD92_RS24180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GGD92_RS24190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GGD92_RS24195	COG0768	penicillin binding
GGD92_RS24200	COG0772	Belongs to the SEDS family
GGD92_RS24205	COG2951	lytic endotransglycosylase activity
GGD92_RS24215	COG1686	Belongs to the peptidase S11 family
GGD92_RS24220	COG2921	Belongs to the UPF0250 family
GGD92_RS24225	COG0321	lipoyl(octanoyl) transferase activity
GGD92_RS24230	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GGD92_RS24235	COG1619	proteins homologs of microcin C7 resistance protein MccF
GGD92_RS24240	COG2951	lytic endotransglycosylase activity
GGD92_RS24260	COG0495	leucyl-tRNA aminoacylation
GGD92_RS24275	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GGD92_RS24280	COG4535	Mg2 and Co2 transporter CorC
GGD92_RS24285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GGD92_RS24290	COG1702	phosphate starvation-inducible protein PhoH
GGD92_RS24295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GGD92_RS24310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GGD92_RS24315	COG0352	thiamine-phosphate diphosphorylase activity
GGD92_RS24320	COG0351	phosphomethylpyrimidine kinase
GGD92_RS24325	COG2205	protein histidine kinase activity
GGD92_RS24325	COG4999	Histidine kinase
GGD92_RS24325	COG3850	Histidine kinase
GGD92_RS24325	COG3437	response regulator, receiver
GGD92_RS24330	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS24335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GGD92_RS24350	COG1522	sequence-specific DNA binding
GGD92_RS24360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GGD92_RS24370	COG1643	Atp-dependent helicase
GGD92_RS24385	COG3416	Protein conserved in bacteria
GGD92_RS24400	COG1522	sequence-specific DNA binding
GGD92_RS24405	COG0697	spore germination
GGD92_RS24425	COG0513	Belongs to the DEAD box helicase family
GGD92_RS24435	COG0123	including yeast histone deacetylase and acetoin utilization protein
GGD92_RS24445	COG1946	Acyl-CoA thioesterase
GGD92_RS24460	COG2321	neutral zinc metallopeptidase
GGD92_RS24465	COG0583	DNA-binding transcription factor activity
GGD92_RS24470	COG3485	protocatechuate 3,4-dioxygenase
GGD92_RS24475	COG3485	protocatechuate 3,4-dioxygenase
GGD92_RS24480	COG0656	L-ascorbic acid biosynthetic process
GGD92_RS24490	COG0673	inositol 2-dehydrogenase activity
GGD92_RS24500	COG0697	spore germination
GGD92_RS24515	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GGD92_RS24515	COG1082	Xylose isomerase domain protein TIM barrel
GGD92_RS24520	COG1309	transcriptional regulator
GGD92_RS24530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GGD92_RS24535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GGD92_RS24555	COG1629	transport
GGD92_RS24565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGD92_RS24570	COG2252	PERMEase
GGD92_RS24585	COG3093	addiction module antidote protein HigA
GGD92_RS24600	COG1271	oxidase subunit
GGD92_RS24605	COG1294	oxidase, subunit
GGD92_RS24615	COG2813	Specifically methylates the guanine in position
GGD92_RS24625	COG1970	mechanosensitive ion channel activity
GGD92_RS24655	COG1966	Carbon starvation protein
GGD92_RS24660	COG2879	small protein
GGD92_RS24665	COG0523	cobalamin synthesis protein
GGD92_RS24685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGD92_RS24695	COG0488	(ABC) transporter
GGD92_RS24705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGD92_RS24725	COG1067	ATP-dependent peptidase activity
GGD92_RS24740	COG2862	Uncharacterized protein family, UPF0114
GGD92_RS24750	COG0545	Peptidyl-prolyl cis-trans isomerase
GGD92_RS24755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGD92_RS24760	COG2824	Alkylphosphonate utilization operon protein PhnA
GGD92_RS24765	COG0142	geranyltranstransferase activity
GGD92_RS24770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GGD92_RS24775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GGD92_RS24780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GGD92_RS24785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GGD92_RS24790	COG3045	CreA protein
GGD92_RS24795	COG0268	Binds directly to 16S ribosomal RNA
GGD92_RS24805	COG0196	riboflavin kinase activity
GGD92_RS24810	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GGD92_RS24815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GGD92_RS24820	COG1047	Peptidyl-prolyl cis-trans
GGD92_RS24825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GGD92_RS24860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS24890	COG0542	response to heat
GGD92_RS24915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS24915	COG2205	protein histidine kinase activity
GGD92_RS24920	COG2197	response regulator
GGD92_RS24925	COG0747	negative chemotaxis
GGD92_RS24930	COG4608	Belongs to the ABC transporter superfamily
GGD92_RS24940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGD92_RS24945	COG0601	transmembrane transport
GGD92_RS24950	COG2197	response regulator
GGD92_RS24955	COG2267	carboxylic ester hydrolase activity
GGD92_RS24960	COG1252	NADH dehydrogenase
GGD92_RS24990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GGD92_RS24995	COG0237	dephospho-CoA kinase activity
GGD92_RS25000	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GGD92_RS25015	COG2823	Periplasmic or secreted lipoprotein
GGD92_RS25025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGD92_RS25035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGD92_RS25040	COG0166	Belongs to the GPI family
GGD92_RS25045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GGD92_RS25050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GGD92_RS25070	COG4191	Histidine kinase
GGD92_RS25080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GGD92_RS25090	COG0436	Aminotransferase
GGD92_RS25095	COG1489	DNA binding
GGD92_RS25105	COG4558	Periplasmic binding protein
GGD92_RS25110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGD92_RS25115	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGD92_RS25145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGD92_RS25160	COG0028	Belongs to the TPP enzyme family
GGD92_RS25170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GGD92_RS25175	COG1183	phosphatidylcholine synthase activity
GGD92_RS25180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GGD92_RS25185	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GGD92_RS25215	COG2995	paraquat-inducible protein a
GGD92_RS25220	COG2995	paraquat-inducible protein a
GGD92_RS25225	COG3008	intermembrane lipid transfer
GGD92_RS25250	COG0456	acetyltransferase
GGD92_RS25260	COG0288	reversible hydration of carbon dioxide
GGD92_RS25275	COG0443	Heat shock 70 kDa protein
GGD92_RS25285	COG2031	fatty acid transporter
GGD92_RS25295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS25300	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GGD92_RS25370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGD92_RS25375	COG0583	DNA-binding transcription factor activity
GGD92_RS25385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GGD92_RS25395	COG0583	DNA-binding transcription factor activity
GGD92_RS25400	COG4251	negative regulation of phosphorylation
GGD92_RS25410	COG0662	Cupin 2, conserved barrel domain protein
GGD92_RS25435	COG0789	Transcriptional regulator
GGD92_RS25445	COG4680	protein conserved in bacteria
GGD92_RS25465	COG0405	Gamma-glutamyltransferase
GGD92_RS25470	COG1858	cytochrome C peroxidase
GGD92_RS25590	COG1177	transmembrane transport
GGD92_RS25595	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGD92_RS25600	COG3842	ATPase activity
GGD92_RS25605	COG0583	DNA-binding transcription factor activity
GGD92_RS25615	COG2223	nitrite transmembrane transporter activity
GGD92_RS25620	COG3292	Two component regulator propeller
GGD92_RS25620	COG2205	protein histidine kinase activity
GGD92_RS25620	COG0745	RESPONSE REGULATOR receiver
GGD92_RS25630	COG4771	TonB-dependent receptor
GGD92_RS25640	COG0193	aminoacyl-tRNA hydrolase activity
GGD92_RS25645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GGD92_RS25650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGD92_RS25660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GGD92_RS25665	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GGD92_RS25675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GGD92_RS25680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GGD92_RS25690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGD92_RS25695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GGD92_RS25715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGD92_RS25730	COG4221	oxidoreductase activity
GGD92_RS25740	COG0415	Belongs to the DNA photolyase family
GGD92_RS25745	COG0789	Transcriptional regulator
GGD92_RS25760	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
GGD92_RS25765	COG1090	epimerase
GGD92_RS25770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GGD92_RS25780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GGD92_RS25785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GGD92_RS25845	COG2135	peptidase activity
GGD92_RS25850	COG0840	transmembrane signaling receptor activity
GGD92_RS25855	COG0501	Belongs to the peptidase M48B family
GGD92_RS25860	COG2119	membrane
GGD92_RS25865	COG2813	Specifically methylates the guanine in position
GGD92_RS25870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGD92_RS25875	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS25885	COG2814	Major facilitator Superfamily
GGD92_RS25890	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS25910	COG0583	DNA-binding transcription factor activity
GGD92_RS25915	COG0642	Histidine kinase
GGD92_RS25930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GGD92_RS25935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGD92_RS25955	COG0180	Tryptophanyl-tRNA synthetase
GGD92_RS25960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGD92_RS25970	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS25975	COG0667	Aldo Keto reductase
GGD92_RS25980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GGD92_RS25985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GGD92_RS25990	COG0723	plastoquinol--plastocyanin reductase activity
GGD92_RS25995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GGD92_RS26000	COG2857	Cytochrome c1
GGD92_RS26005	COG0625	glutathione transferase activity
GGD92_RS26010	COG2969	positive regulation of protein catabolic process
GGD92_RS26015	COG2823	Periplasmic or secreted lipoprotein
GGD92_RS26020	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGD92_RS26025	COG0792	nuclease activity
GGD92_RS26045	COG2001	Belongs to the MraZ family
GGD92_RS26050	COG0275	rRNA processing
GGD92_RS26065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGD92_RS26070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGD92_RS26075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGD92_RS26080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GGD92_RS26085	COG0772	Belongs to the SEDS family
GGD92_RS26090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GGD92_RS26095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GGD92_RS26100	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGD92_RS26115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GGD92_RS26120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GGD92_RS26125	COG2203	Gaf domain
GGD92_RS26125	COG3706	GGDEF domain
GGD92_RS26125	COG4251	negative regulation of phosphorylation
GGD92_RS26125	COG5001	Diguanylate cyclase
GGD92_RS26140	COG5002	protein histidine kinase activity
GGD92_RS26165	COG0840	transmembrane signaling receptor activity
GGD92_RS26185	COG3604	Transcriptional regulator
GGD92_RS26190	COG1017	nitric oxide dioxygenase activity
GGD92_RS26190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGD92_RS26195	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GGD92_RS26200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGD92_RS26205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGD92_RS26210	COG1845	cytochrome c oxidase, subunit III
GGD92_RS26220	COG0109	protoheme IX farnesyltransferase activity
GGD92_RS26275	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGD92_RS26315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS26335	COG0537	adenosine 5'-monophosphoramidase activity
GGD92_RS26375	COG0586	Pfam SNARE associated Golgi protein
GGD92_RS26445	COG0625	glutathione transferase activity
GGD92_RS26465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GGD92_RS26470	COG0343	queuine tRNA-ribosyltransferase activity
GGD92_RS26475	COG1862	Preprotein translocase
GGD92_RS26490	COG3134	Outer membrane lipoprotein
GGD92_RS26505	COG1045	serine acetyltransferase
GGD92_RS26515	COG1104	cysteine desulfurase activity
GGD92_RS26530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GGD92_RS26535	COG0443	Heat shock 70 kDa protein
GGD92_RS26540	COG0633	Ferredoxin
GGD92_RS26550	COG0105	UTP biosynthetic process
GGD92_RS26555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GGD92_RS26565	COG1426	Protein conserved in bacteria
GGD92_RS26570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GGD92_RS26575	COG0124	histidyl-tRNA synthetase
GGD92_RS26590	COG1160	GTP binding
GGD92_RS26595	COG0436	Aminotransferase
GGD92_RS26600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGD92_RS26610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GGD92_RS26615	COG0739	heme binding
GGD92_RS26620	COG1570	exodeoxyribonuclease VII activity
GGD92_RS26645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GGD92_RS26645	COG0519	Catalyzes the synthesis of GMP from XMP
GGD92_RS26650	COG0024	Methionine aminopeptidase
GGD92_RS26665	COG2188	Transcriptional regulator
GGD92_RS26670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGD92_RS26670	COG1263	PTS System
GGD92_RS26675	COG0366	Alpha amylase catalytic
GGD92_RS26685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGD92_RS26685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGD92_RS26700	COG0590	tRNA wobble adenosine to inosine editing
GGD92_RS26705	COG0500	methyltransferase
GGD92_RS26710	COG2226	methyltransferase
GGD92_RS26725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GGD92_RS26740	COG2197	response regulator
GGD92_RS26800	COG3135	benzoate transporter
GGD92_RS26805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS26810	COG4206	TonB-dependent receptor
GGD92_RS26815	COG4628	conserved protein (DUF2132)
GGD92_RS26825	COG2375	cellular response to nickel ion
GGD92_RS26830	COG1695	Transcriptional regulator
GGD92_RS26845	COG1113	amino acid transport
GGD92_RS26860	COG2267	carboxylic ester hydrolase activity
GGD92_RS26875	COG0069	glutamate synthase activity
GGD92_RS26880	COG2197	response regulator
GGD92_RS26890	COG0531	amino acid
GGD92_RS26895	COG0254	rRNA binding
GGD92_RS26910	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS26920	COG0583	DNA-binding transcription factor activity
GGD92_RS26925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGD92_RS26940	COG4191	Histidine kinase
GGD92_RS26955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGD92_RS26975	COG2076	Multidrug Resistance protein
GGD92_RS27005	COG1126	abc transporter atp-binding protein
GGD92_RS27010	COG0765	amino acid transport
GGD92_RS27015	COG0765	amino acid transport
GGD92_RS27020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS27035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGD92_RS27045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGD92_RS27055	COG3842	ATPase activity
GGD92_RS27060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGD92_RS27065	COG3383	formate dehydrogenase (NAD+) activity
GGD92_RS27070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GGD92_RS27085	COG0450	alkyl hydroperoxide reductase
GGD92_RS27090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GGD92_RS27095	COG0418	dihydroorotase activity
GGD92_RS27105	COG0137	argininosuccinate synthase activity
GGD92_RS27110	COG2197	response regulator
GGD92_RS27120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGD92_RS27135	COG4658	electron transport chain
GGD92_RS27140	COG2878	Part of a membrane complex involved in electron transport
GGD92_RS27150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGD92_RS27150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGD92_RS27155	COG0489	protein tyrosine kinase activity
GGD92_RS27160	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS27170	COG3030	protein affecting phage T7 exclusion by the F plasmid
GGD92_RS27175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GGD92_RS27180	COG0459	protein refolding
GGD92_RS27185	COG1368	sulfuric ester hydrolase activity
GGD92_RS27195	COG0642	Histidine kinase
GGD92_RS27205	COG3642	lipopolysaccharide core region biosynthetic process
GGD92_RS27240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GGD92_RS27255	COG0583	DNA-binding transcription factor activity
GGD92_RS27260	COG0702	epimerase
GGD92_RS27290	COG0583	DNA-binding transcription factor activity
GGD92_RS27300	COG2910	NAD(P)H-binding
GGD92_RS27305	COG0583	DNA-binding transcription factor activity
GGD92_RS27315	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS27320	COG2207	Transcriptional regulator
GGD92_RS27350	COG0477	Major facilitator Superfamily
GGD92_RS27360	COG4191	Histidine kinase
GGD92_RS27370	COG3706	GGDEF domain
GGD92_RS27380	COG1024	Enoyl-CoA hydratase
GGD92_RS27385	COG0469	pyruvate kinase activity
GGD92_RS27405	COG0714	Associated with various cellular activities
GGD92_RS27430	COG2925	Exonuclease
GGD92_RS27455	COG0433	COG0433 Predicted ATPase
GGD92_RS27465	COG0653	protein targeting
GGD92_RS27470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GGD92_RS27475	COG0352	thiamine-phosphate diphosphorylase activity
GGD92_RS27480	COG2096	Adenosyltransferase
GGD92_RS27485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS27485	COG4191	Histidine kinase
GGD92_RS27495	COG1666	GTP binding
GGD92_RS27500	COG0668	transmembrane transport
GGD92_RS27515	COG2900	Belongs to the SlyX family
GGD92_RS27525	COG0783	Belongs to the Dps family
GGD92_RS27535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GGD92_RS27540	COG0217	transcriptional regulatory protein
GGD92_RS27545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GGD92_RS27550	COG0632	four-way junction helicase activity
GGD92_RS27555	COG2255	four-way junction helicase activity
GGD92_RS27560	COG0824	Thioesterase
GGD92_RS27580	COG0823	Involved in the tonB-independent uptake of proteins
GGD92_RS27585	COG2885	chlorophyll binding
GGD92_RS27590	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GGD92_RS27595	COG0602	queuosine metabolic process
GGD92_RS27600	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GGD92_RS27620	COG4964	Belongs to the GSP D family
GGD92_RS27640	COG0642	Histidine kinase
GGD92_RS27645	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GGD92_RS27655	COG1278	Cold shock
GGD92_RS27660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GGD92_RS27665	COG1760	l-serine dehydratase
GGD92_RS27670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GGD92_RS27670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GGD92_RS27675	COG0509	glycine decarboxylation via glycine cleavage system
GGD92_RS27695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGD92_RS27720	COG0840	transmembrane signaling receptor activity
GGD92_RS27725	COG2832	Protein of unknown function (DUF454)
GGD92_RS27735	COG4771	TonB-dependent receptor
GGD92_RS27740	COG3712	iron ion homeostasis
GGD92_RS27745	COG1595	DNA-templated transcription, initiation
GGD92_RS27750	COG1803	Methylglyoxal synthase
GGD92_RS27785	COG1653	transport
GGD92_RS27790	COG1175	transmembrane transport
GGD92_RS27795	COG0395	ABC-type sugar transport system, permease component
GGD92_RS27800	COG3842	ATPase activity
GGD92_RS27810	COG0676	glucose-6-phosphate 1-epimerase activity
GGD92_RS27815	COG1737	Transcriptional regulator
GGD92_RS27830	COG0800	Aldolase
GGD92_RS27835	COG3530	Putative quorum-sensing-regulated virulence factor
GGD92_RS27855	COG1566	PFAM secretion protein HlyD family protein
GGD92_RS27860	COG2030	dehydratase
GGD92_RS27870	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS27875	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS27890	COG1295	ribonuclease BN
GGD92_RS27895	COG0242	peptide deformylase activity
GGD92_RS27910	COG0583	DNA-binding transcription factor activity
GGD92_RS27940	COG0583	DNA-binding transcription factor activity
GGD92_RS27950	COG1280	lysine exporter protein (LysE YggA)
GGD92_RS27955	COG1609	Transcriptional regulator
GGD92_RS27960	COG3265	gluconokinase activity
GGD92_RS27970	COG0436	Aminotransferase
GGD92_RS27995	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GGD92_RS28005	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GGD92_RS28010	COG2205	protein histidine kinase activity
GGD92_RS28015	COG0745	RESPONSE REGULATOR receiver
GGD92_RS28040	COG0456	acetyltransferase
GGD92_RS28050	COG3795	YCII-related domain
GGD92_RS28060	COG4941	Belongs to the sigma-70 factor family
GGD92_RS28065	COG0583	DNA-binding transcription factor activity
GGD92_RS28075	COG2995	paraquat-inducible protein a
GGD92_RS28080	COG2995	paraquat-inducible protein a
GGD92_RS28085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GGD92_RS28085	COG3008	intermembrane lipid transfer
GGD92_RS28100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GGD92_RS28105	COG0511	ligase activity, forming carbon-carbon bonds
GGD92_RS28120	COG1984	allophanate hydrolase subunit 2
GGD92_RS28130	COG0306	phosphate transporter
GGD92_RS28165	COG0584	glycerophosphoryl diester phosphodiesterase
GGD92_RS28175	COG2329	Antibiotic biosynthesis monooxygenase
GGD92_RS28180	COG0504	CTP synthase activity
GGD92_RS28200	COG3706	GGDEF domain
GGD92_RS28235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGD92_RS28245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGD92_RS28250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS28280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGD92_RS28295	COG1012	belongs to the aldehyde dehydrogenase family
GGD92_RS28300	COG3724	N-succinylarginine dihydrolase activity
GGD92_RS28310	COG2988	succinylglutamate desuccinylase activity
GGD92_RS28315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GGD92_RS28320	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GGD92_RS28325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GGD92_RS28330	COG0527	aspartate kinase activity
GGD92_RS28335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GGD92_RS28355	COG2239	Acts as a magnesium transporter
GGD92_RS28430	COG2205	protein histidine kinase activity
GGD92_RS28440	COG0477	Major facilitator Superfamily
GGD92_RS28445	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GGD92_RS28465	COG0835	chemotaxis
GGD92_RS28465	COG0784	Response regulator, receiver
GGD92_RS28470	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGD92_RS28475	COG1815	bacterial-type flagellum-dependent cell motility
GGD92_RS28480	COG1558	bacterial-type flagellum-dependent cell motility
GGD92_RS28485	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GGD92_RS28500	COG0745	RESPONSE REGULATOR receiver
GGD92_RS28505	COG2205	protein histidine kinase activity
GGD92_RS28510	COG2977	Belongs to the P-Pant transferase superfamily
GGD92_RS28535	COG1301	dicarboxylic acid transport
GGD92_RS28540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GGD92_RS28545	COG3091	SprT-like family
GGD92_RS28555	COG0037	tRNA processing
GGD92_RS28560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGD92_RS28565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGD92_RS28590	COG1393	Belongs to the ArsC family
GGD92_RS28595	COG3118	belongs to the thioredoxin family
GGD92_RS28610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGD92_RS28615	COG0784	Response regulator, receiver
GGD92_RS28615	COG2205	protein histidine kinase activity
GGD92_RS28615	COG5002	protein histidine kinase activity
GGD92_RS28635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGD92_RS28640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGD92_RS28645	COG3956	TIGRFAM MazG family protein
GGD92_RS28650	COG3122	Protein conserved in bacteria
GGD92_RS28665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GGD92_RS28670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GGD92_RS28680	COG0628	permease
GGD92_RS28685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GGD92_RS28690	COG0791	NLP P60 protein
GGD92_RS28695	COG0791	NLP P60 protein
GGD92_RS28720	COG1797	cobyrinic acid a,c-diamide synthase activity
GGD92_RS28725	COG0778	Nitroreductase
GGD92_RS28740	COG1492	cobalamin metabolic process
GGD92_RS28750	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GGD92_RS28755	COG0406	alpha-ribazole phosphatase activity
GGD92_RS28760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GGD92_RS28805	COG2205	protein histidine kinase activity
GGD92_RS28840	COG0385	Bile acid
GGD92_RS28845	COG2974	May be involved in recombination
GGD92_RS28875	COG2010	Cytochrome c
GGD92_RS28880	COG0545	Peptidyl-prolyl cis-trans isomerase
GGD92_RS28905	COG2200	EAL domain
GGD92_RS28915	COG0604	alcohol dehydrogenase
GGD92_RS28915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGD92_RS28915	COG3321	synthase
GGD92_RS28915	COG4221	oxidoreductase activity
GGD92_RS28925	COG3842	ATPase activity
GGD92_RS28935	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGD92_RS28955	COG0668	transmembrane transport
GGD92_RS28965	COG1362	aminopeptidase activity
GGD92_RS28975	COG0564	pseudouridine synthase activity
GGD92_RS28980	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GGD92_RS28985	COG2894	cell division
GGD92_RS28990	COG0850	regulation of cytokinetic process
GGD92_RS28995	COG1560	Kdo2-lipid A biosynthetic process
GGD92_RS29010	COG2233	PERMEase
GGD92_RS29020	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GGD92_RS29040	COG2252	PERMEase
GGD92_RS29050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGD92_RS29055	COG0625	glutathione transferase activity
GGD92_RS29065	COG0302	gtp cyclohydrolase
GGD92_RS29070	COG2840	Smr protein MutS2
GGD92_RS29095	COG1073	alpha beta
GGD92_RS29100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GGD92_RS29110	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GGD92_RS29125	COG0318	PFAM AMP-dependent synthetase and ligase
GGD92_RS29145	COG1368	sulfuric ester hydrolase activity
GGD92_RS29155	COG3121	Chaperone
GGD92_RS29160	COG3188	usher protein
GGD92_RS29180	COG1742	UPF0060 membrane protein
GGD92_RS29185	COG3089	Belongs to the UPF0270 family
GGD92_RS29190	COG1363	Peptidase, m42
GGD92_RS29195	COG0189	ligase activity
GGD92_RS29195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGD92_RS29200	COG0367	asparagine synthase
GGD92_RS29205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS29205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GGD92_RS29210	COG2326	polyphosphate kinase activity
GGD92_RS29215	COG0183	Belongs to the thiolase family
GGD92_RS29220	COG0697	spore germination
GGD92_RS29225	COG0114	fumarate hydratase activity
GGD92_RS29235	COG0271	Belongs to the BolA IbaG family
GGD92_RS29240	COG1054	Belongs to the UPF0176 family
GGD92_RS29255	COG5002	protein histidine kinase activity
GGD92_RS29255	COG5001	Diguanylate cyclase
GGD92_RS29270	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS29275	COG0546	phosphoglycolate phosphatase activity
GGD92_RS29280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGD92_RS29285	COG0402	S-adenosylhomocysteine deaminase activity
GGD92_RS29290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GGD92_RS29300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GGD92_RS29310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GGD92_RS29315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GGD92_RS29320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GGD92_RS29330	COG0776	regulation of translation
GGD92_RS29340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGD92_RS29350	COG1555	photosystem II stabilization
GGD92_RS29375	COG0531	amino acid
GGD92_RS29385	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GGD92_RS29395	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GGD92_RS29400	COG2205	protein histidine kinase activity
GGD92_RS29445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGD92_RS29460	COG2197	response regulator
GGD92_RS29465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGD92_RS29470	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GGD92_RS29475	COG4181	ATPase activity
GGD92_RS29490	COG1376	ErfK ybiS ycfS ynhG family protein
GGD92_RS29520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GGD92_RS29555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGD92_RS29560	COG1764	response to oxidative stress
GGD92_RS29565	COG1846	Transcriptional regulator
GGD92_RS29570	COG0583	DNA-binding transcription factor activity
GGD92_RS29580	COG0583	DNA-binding transcription factor activity
GGD92_RS29590	COG3214	Protein conserved in bacteria
GGD92_RS29595	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GGD92_RS29605	COG1024	Enoyl-CoA hydratase
GGD92_RS29615	COG3384	dioxygenase
GGD92_RS29620	COG0500	methyltransferase
GGD92_RS29625	COG0501	Belongs to the peptidase M48B family
GGD92_RS29630	COG0436	Aminotransferase
GGD92_RS29635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGD92_RS29640	COG0386	Belongs to the glutathione peroxidase family
GGD92_RS29645	COG1846	Transcriptional regulator
GGD92_RS29650	COG5002	protein histidine kinase activity
GGD92_RS29650	COG2205	protein histidine kinase activity
GGD92_RS29650	COG0784	Response regulator, receiver
GGD92_RS29660	COG1956	GAF domain-containing protein
GGD92_RS29665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGD92_RS29670	COG2205	protein histidine kinase activity
GGD92_RS29670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGD92_RS29675	COG2197	response regulator
GGD92_RS29695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GGD92_RS29715	COG0004	ammonium transporteR
GGD92_RS29740	COG0564	pseudouridine synthase activity
GGD92_RS29750	COG0521	Mo-molybdopterin cofactor biosynthetic process
GGD92_RS29755	COG0303	'Molybdopterin
GGD92_RS29770	COG1597	lipid kinase activity
GGD92_RS29775	COG2197	response regulator
GGD92_RS29780	COG3851	Histidine kinase
GGD92_RS29795	COG3217	Mosc domain protein beta barrel domain protein
GGD92_RS29795	COG0633	Ferredoxin
GGD92_RS29800	COG3123	guanosine phosphorylase activity
GGD92_RS29815	COG1024	Enoyl-CoA hydratase
GGD92_RS29820	COG1960	acyl-CoA dehydrogenase activity
GGD92_RS29825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GGD92_RS29840	COG1309	transcriptional regulator
GGD92_RS29880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGD92_RS29895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGD92_RS29900	COG4232	protein-disulfide reductase activity
GGD92_RS29910	COG0642	Histidine kinase
GGD92_RS29925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGD92_RS29935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGD92_RS29940	COG1121	(ABC) transporter
GGD92_RS29980	COG2011	ABC-type metal ion transport system permease component
GGD92_RS30000	COG3829	transcription factor binding
GGD92_RS30010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GGD92_RS30015	COG0431	NADPH-dependent FMN reductase
GGD92_RS30045	COG1028	Short-chain dehydrogenase reductase Sdr
GGD92_RS30050	COG1309	transcriptional regulator
GGD92_RS30060	COG5006	permease, DMT superfamily
GGD92_RS30090	COG0768	penicillin binding
GGD92_RS30095	COG0583	DNA-binding transcription factor activity
GGD92_RS30100	COG0477	Major facilitator Superfamily
GGD92_RS30115	COG3284	Transcriptional regulator
GGD92_RS30120	COG1132	(ABC) transporter
GGD92_RS30125	COG1404	Belongs to the peptidase S8 family
GGD92_RS30155	COG1595	DNA-templated transcription, initiation
GGD92_RS30160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGD92_RS30190	COG3755	Protein conserved in bacteria
GGD92_RS30230	COG4977	sequence-specific DNA binding
GGD92_RS30240	COG1090	epimerase
GGD92_RS30285	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GGD92_RS30425	COG1136	(ABC) transporter
GGD92_RS30425	COG0577	efflux transmembrane transporter activity
GGD92_RS30430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGD92_RS30445	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GGD92_RS30460	COG0583	DNA-binding transcription factor activity
GGD92_RS30470	COG1335	isochorismatase
GGD92_RS30485	COG2814	Major facilitator Superfamily
GGD92_RS30490	COG1063	alcohol dehydrogenase
GGD92_RS30495	COG0589	response to stress
GGD92_RS30505	COG3459	Glycosyltransferase 36 associated
GGD92_RS30540	COG0730	response to heat
GGD92_RS30550	COG0784	Response regulator, receiver
GGD92_RS30550	COG4191	Histidine kinase
GGD92_RS30595	COG2207	Transcriptional regulator
GGD92_RS30620	COG2223	nitrite transmembrane transporter activity
GGD92_RS30625	COG1522	sequence-specific DNA binding
GGD92_RS30630	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGD92_RS30640	COG0402	S-adenosylhomocysteine deaminase activity
GGD92_RS30645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGD92_RS30660	COG1051	belongs to the nudix hydrolase family
GGD92_RS30665	COG4608	Belongs to the ABC transporter superfamily
GGD92_RS30670	COG0444	Belongs to the ABC transporter superfamily
GGD92_RS30675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGD92_RS30680	COG0601	transmembrane transport
GGD92_RS30685	COG0747	negative chemotaxis
GGD92_RS30690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GGD92_RS30705	COG0720	synthase
GGD92_RS30735	COG0840	transmembrane signaling receptor activity
GGD92_RS30740	COG2056	Na+-H+ antiporter family
GGD92_RS30750	COG0826	peptidase U32
GGD92_RS30755	COG0628	permease
GGD92_RS30770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GGD92_RS30775	COG3132	Protein of unknown function, DUF480
GGD92_RS30795	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GGD92_RS30805	COG0583	DNA-binding transcription factor activity
GGD92_RS30815	COG1253	flavin adenine dinucleotide binding
GGD92_RS30830	COG1686	Belongs to the peptidase S11 family
GGD92_RS30835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GGD92_RS30855	COG0544	peptidyl-prolyl cis-trans isomerase activity
GGD92_RS30860	COG0740	serine-type endopeptidase activity
GGD92_RS30865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GGD92_RS30870	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GGD92_RS30875	COG0776	regulation of translation
GGD92_RS30880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGD92_RS30900	COG0583	DNA-binding transcription factor activity
GGD92_RS30920	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGD92_RS30920	COG1902	pentaerythritol trinitrate reductase activity
GGD92_RS30930	COG3038	cytochrome b561
GGD92_RS30935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGD92_RS30940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGD92_RS30945	COG0583	DNA-binding transcription factor activity
GGD92_RS30950	COG0217	transcriptional regulatory protein
GGD92_RS30960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGD92_RS30970	COG2508	Transcriptional regulator
GGD92_RS30985	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGD92_RS31025	COG2814	Major facilitator Superfamily
GGD92_RS31035	COG2866	Carboxypeptidase
GGD92_RS31045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGD92_RS31050	COG1262	PFAM Formylglycine-generating sulfatase enzyme