locus-tag	class	description
CHR26_RS00025	COG2267	carboxylic ester hydrolase activity
CHR26_RS00065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHR26_RS00080	COG0556	nucleotide-excision repair
CHR26_RS00110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHR26_RS00125	COG0084	hydrolase, TatD family'
CHR26_RS00135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHR26_RS00140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHR26_RS00150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR26_RS00155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR26_RS00170	COG0416	fatty acid biosynthetic process
CHR26_RS00175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHR26_RS00180	COG1399	metal-binding, possibly nucleic acid-binding protein
CHR26_RS00185	COG0424	maF-like protein
CHR26_RS00190	COG0616	signal peptide processing
CHR26_RS00190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHR26_RS00195	COG0546	phosphoglycolate phosphatase activity
CHR26_RS00210	COG1530	ribonuclease E activity
CHR26_RS00215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHR26_RS00220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHR26_RS00225	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CHR26_RS00230	COG2835	tetraacyldisaccharide 4'-kinase activity
CHR26_RS00235	COG1663	tetraacyldisaccharide 4'-kinase activity
CHR26_RS00240	COG0848	biopolymer transport protein
CHR26_RS00245	COG0811	peptide transport
CHR26_RS00250	COG2333	competence protein COMEC
CHR26_RS00250	COG0658	competence protein
CHR26_RS00260	COG0842	Transport permease protein
CHR26_RS00265	COG1131	(ABC) transporter
CHR26_RS00270	COG0625	glutathione transferase activity
CHR26_RS00295	COG3121	Chaperone
CHR26_RS00310	COG3209	COG3209 Rhs family protein
CHR26_RS00355	COG1956	GAF domain-containing protein
CHR26_RS00365	COG0784	Response regulator, receiver
CHR26_RS00365	COG5002	protein histidine kinase activity
CHR26_RS00365	COG2205	protein histidine kinase activity
CHR26_RS00370	COG0386	Belongs to the glutathione peroxidase family
CHR26_RS00375	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR26_RS00380	COG0436	Aminotransferase
CHR26_RS00385	COG0501	Belongs to the peptidase M48B family
CHR26_RS00390	COG0500	methyltransferase
CHR26_RS00395	COG3384	dioxygenase
CHR26_RS00410	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHR26_RS00420	COG0583	DNA-binding transcription factor activity
CHR26_RS00430	COG0583	DNA-binding transcription factor activity
CHR26_RS00435	COG1846	Transcriptional regulator
CHR26_RS00440	COG1764	response to oxidative stress
CHR26_RS00445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHR26_RS00465	COG0583	DNA-binding transcription factor activity
CHR26_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS00475	COG0583	DNA-binding transcription factor activity
CHR26_RS00480	COG2814	Major facilitator Superfamily
CHR26_RS00510	COG0598	Magnesium transport protein CorA
CHR26_RS00515	COG0519	Catalyzes the synthesis of GMP from XMP
CHR26_RS00520	COG2010	Cytochrome c
CHR26_RS00520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR26_RS00535	COG1368	sulfuric ester hydrolase activity
CHR26_RS00575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CHR26_RS00580	COG2814	Major facilitator Superfamily
CHR26_RS00585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHR26_RS00615	COG2840	Smr protein MutS2
CHR26_RS00620	COG0302	gtp cyclohydrolase
CHR26_RS00630	COG0625	glutathione transferase activity
CHR26_RS00635	COG3135	benzoate transporter
CHR26_RS00640	COG0840	transmembrane signaling receptor activity
CHR26_RS00650	COG2130	NADP-dependent
CHR26_RS00655	COG0284	orotidine-5'-phosphate decarboxylase activity
CHR26_RS00665	COG1555	photosystem II stabilization
CHR26_RS00670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHR26_RS00675	COG0166	Belongs to the GPI family
CHR26_RS00690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHR26_RS00705	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS00715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CHR26_RS00725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS00750	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS00750	COG1216	Glycosyl transferase, family 2
CHR26_RS00755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR26_RS00760	COG1083	cytidylyl-transferase
CHR26_RS00820	COG0463	Glycosyl transferase, family 2
CHR26_RS00835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR26_RS00850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR26_RS00860	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHR26_RS00870	COG0776	regulation of translation
CHR26_RS00880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHR26_RS00885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHR26_RS00895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CHR26_RS00910	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CHR26_RS00915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR26_RS00920	COG0546	phosphoglycolate phosphatase activity
CHR26_RS00925	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS00935	COG5002	protein histidine kinase activity
CHR26_RS00935	COG5001	Diguanylate cyclase
CHR26_RS00950	COG1054	Belongs to the UPF0176 family
CHR26_RS00955	COG0271	Belongs to the BolA IbaG family
CHR26_RS00965	COG0114	fumarate hydratase activity
CHR26_RS00970	COG0697	spore germination
CHR26_RS00975	COG2326	polyphosphate kinase activity
CHR26_RS00980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS00980	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CHR26_RS00985	COG0367	asparagine synthase
CHR26_RS00990	COG0189	ligase activity
CHR26_RS00990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHR26_RS00995	COG1363	Peptidase, m42
CHR26_RS01000	COG3089	Belongs to the UPF0270 family
CHR26_RS01020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR26_RS01025	COG3162	membrane
CHR26_RS01030	COG2113	Glycine betaine
CHR26_RS01050	COG2853	Lipoprotein
CHR26_RS01060	COG1560	Kdo2-lipid A biosynthetic process
CHR26_RS01065	COG0850	regulation of cytokinetic process
CHR26_RS01070	COG2894	cell division
CHR26_RS01075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CHR26_RS01080	COG0564	pseudouridine synthase activity
CHR26_RS01085	COG1362	aminopeptidase activity
CHR26_RS01095	COG0668	transmembrane transport
CHR26_RS01115	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR26_RS01145	COG5001	Diguanylate cyclase
CHR26_RS01145	COG3300	MHYT domain
CHR26_RS01160	COG3339	Conserved Protein
CHR26_RS01165	COG0545	Peptidyl-prolyl cis-trans isomerase
CHR26_RS01175	COG0583	DNA-binding transcription factor activity
CHR26_RS01180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR26_RS01180	COG2146	nitrite reductase [NAD(P)H] activity
CHR26_RS01185	COG2146	nitrite reductase [NAD(P)H] activity
CHR26_RS01185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR26_RS01190	COG0243	molybdopterin cofactor binding
CHR26_RS01200	COG0024	Methionine aminopeptidase
CHR26_RS01225	COG2974	May be involved in recombination
CHR26_RS01230	COG0385	Bile acid
CHR26_RS01240	COG2076	Multidrug Resistance protein
CHR26_RS01245	COG0477	Major facilitator Superfamily
CHR26_RS01250	COG2814	Major facilitator Superfamily
CHR26_RS01255	COG2205	protein histidine kinase activity
CHR26_RS01285	COG0583	DNA-binding transcription factor activity
CHR26_RS01315	COG1846	Transcriptional regulator
CHR26_RS01325	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CHR26_RS01335	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHR26_RS01345	COG1492	cobalamin metabolic process
CHR26_RS01360	COG0778	Nitroreductase
CHR26_RS01365	COG1797	cobyrinic acid a,c-diamide synthase activity
CHR26_RS01385	COG0791	NLP P60 protein
CHR26_RS01390	COG0791	NLP P60 protein
CHR26_RS01405	COG0628	permease
CHR26_RS01415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHR26_RS01420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHR26_RS01435	COG3122	Protein conserved in bacteria
CHR26_RS01440	COG3956	TIGRFAM MazG family protein
CHR26_RS01445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR26_RS01450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR26_RS01470	COG0784	Response regulator, receiver
CHR26_RS01470	COG2205	protein histidine kinase activity
CHR26_RS01470	COG5002	protein histidine kinase activity
CHR26_RS01475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR26_RS01520	COG0037	tRNA processing
CHR26_RS01530	COG3091	SprT-like family
CHR26_RS01540	COG0583	DNA-binding transcription factor activity
CHR26_RS01555	COG3148	PFAM DTW domain containing protein
CHR26_RS01575	COG2137	regulation of response to DNA damage stimulus
CHR26_RS01580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHR26_RS01585	COG1546	Belongs to the CinA family
CHR26_RS01595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHR26_RS01600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CHR26_RS01615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHR26_RS01620	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CHR26_RS01625	COG0585	pseudouridine synthase activity
CHR26_RS01630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHR26_RS01640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CHR26_RS01650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHR26_RS01660	COG0148	phosphopyruvate hydratase activity
CHR26_RS01665	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CHR26_RS01670	COG0504	CTP synthase activity
CHR26_RS01675	COG0037	tRNA processing
CHR26_RS01680	COG0825	malonyl-CoA metabolic process
CHR26_RS01690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHR26_RS01695	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR26_RS01700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR26_RS01705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHR26_RS01710	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR26_RS01730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHR26_RS01740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHR26_RS01745	COG0233	cytoplasmic translational termination
CHR26_RS01750	COG0528	UMP kinase activity
CHR26_RS01755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHR26_RS01760	COG0052	Belongs to the universal ribosomal protein uS2 family
CHR26_RS01765	COG0024	Methionine aminopeptidase
CHR26_RS01770	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CHR26_RS01775	COG0436	Aminotransferase
CHR26_RS01780	COG0025	NhaP-type Na H and K H
CHR26_RS01785	COG1393	Belongs to the ArsC family
CHR26_RS01790	COG2171	N-acyltransferase activity
CHR26_RS01795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHR26_RS01805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHR26_RS01810	COG1215	transferase activity, transferring glycosyl groups
CHR26_RS01820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR26_RS01825	COG2226	methyltransferase
CHR26_RS01840	COG2937	Belongs to the GPAT DAPAT family
CHR26_RS01860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS01870	COG0742	ribosomal rna small subunit methyltransferase
CHR26_RS01905	COG0563	adenylate kinase activity
CHR26_RS01910	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CHR26_RS01925	COG2885	chlorophyll binding
CHR26_RS01955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHR26_RS01965	COG4251	negative regulation of phosphorylation
CHR26_RS01965	COG3706	GGDEF domain
CHR26_RS01965	COG5001	Diguanylate cyclase
CHR26_RS01965	COG2203	Gaf domain
CHR26_RS01970	COG2201	protein-glutamate methylesterase activity
CHR26_RS01980	COG0835	chemotaxis
CHR26_RS01985	COG0457	Tetratricopeptide repeat
CHR26_RS01985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHR26_RS01995	COG0840	transmembrane signaling receptor activity
CHR26_RS02000	COG2979	Protein of unknown function (DUF533)
CHR26_RS02005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHR26_RS02010	COG3842	ATPase activity
CHR26_RS02015	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR26_RS02020	COG1177	transmembrane transport
CHR26_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS02030	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS02045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHR26_RS02080	COG4974	Belongs to the 'phage' integrase family
CHR26_RS02085	COG1607	acyl-coa hydrolase
CHR26_RS02090	COG0335	large ribosomal subunit rRNA binding
CHR26_RS02095	COG0336	Belongs to the RNA methyltransferase TrmD family
CHR26_RS02100	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHR26_RS02105	COG0228	four-way junction DNA binding
CHR26_RS02110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHR26_RS02120	COG4536	flavin adenine dinucleotide binding
CHR26_RS02125	COG0477	Major facilitator Superfamily
CHR26_RS02130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CHR26_RS02215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR26_RS02250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR26_RS02265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHR26_RS02265	COG0047	phosphoribosylformylglycinamidine synthase activity
CHR26_RS02270	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CHR26_RS02275	COG0590	tRNA wobble adenosine to inosine editing
CHR26_RS02285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHR26_RS02285	COG0519	Catalyzes the synthesis of GMP from XMP
CHR26_RS02305	COG0583	DNA-binding transcription factor activity
CHR26_RS02310	COG1570	exodeoxyribonuclease VII activity
CHR26_RS02315	COG0739	heme binding
CHR26_RS02325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR26_RS02330	COG0800	Aldolase
CHR26_RS02345	COG1737	Transcriptional regulator
CHR26_RS02350	COG0676	glucose-6-phosphate 1-epimerase activity
CHR26_RS02360	COG3842	ATPase activity
CHR26_RS02370	COG1175	transmembrane transport
CHR26_RS02430	COG2832	Protein of unknown function (DUF454)
CHR26_RS02450	COG2235	arginine
CHR26_RS02455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR26_RS02475	COG0786	glutamate:sodium symporter activity
CHR26_RS02490	COG0509	glycine decarboxylation via glycine cleavage system
CHR26_RS02495	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR26_RS02495	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR26_RS02500	COG1760	l-serine dehydratase
CHR26_RS02505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR26_RS02510	COG1278	Cold shock
CHR26_RS02520	COG0795	lipopolysaccharide-transporting ATPase activity
CHR26_RS02525	COG0795	lipopolysaccharide-transporting ATPase activity
CHR26_RS02535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHR26_RS02550	COG0525	valine-tRNA ligase activity
CHR26_RS02555	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CHR26_RS02560	COG0776	regulation of translation
CHR26_RS02565	COG3081	Nucleoid-associated protein
CHR26_RS02570	COG2827	Endonuclease containing a URI domain
CHR26_RS02585	COG2807	transmembrane transport
CHR26_RS02590	COG2186	Transcriptional regulator
CHR26_RS02595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR26_RS02600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHR26_RS02605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHR26_RS02610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHR26_RS02630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CHR26_RS02635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHR26_RS02640	COG1127	ABC transporter
CHR26_RS02650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CHR26_RS02660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CHR26_RS02665	COG1137	ATPase activity
CHR26_RS02670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHR26_RS02675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHR26_RS02685	COG1660	Displays ATPase and GTPase activities
CHR26_RS02690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR26_RS02720	COG0312	modulator of DNA gyrase
CHR26_RS02725	COG3028	Belongs to the UPF0307 family
CHR26_RS02730	COG0312	modulator of DNA gyrase
CHR26_RS02735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR26_RS02750	COG0424	maF-like protein
CHR26_RS02760	COG1792	Involved in formation and maintenance of cell shape
CHR26_RS02765	COG1077	Cell shape determining protein MreB Mrl
CHR26_RS02770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR26_RS02775	COG0154	amidase activity
CHR26_RS02780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR26_RS02795	COG1113	amino acid transport
CHR26_RS02805	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CHR26_RS02820	COG0747	negative chemotaxis
CHR26_RS02825	COG0747	negative chemotaxis
CHR26_RS02835	COG0747	negative chemotaxis
CHR26_RS02840	COG0601	transmembrane transport
CHR26_RS02845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR26_RS02850	COG0444	Belongs to the ABC transporter superfamily
CHR26_RS02855	COG4608	Belongs to the ABC transporter superfamily
CHR26_RS02870	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CHR26_RS02885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CHR26_RS02910	COG4772	TonB-dependent receptor
CHR26_RS02925	COG0019	diaminopimelate decarboxylase activity
CHR26_RS02940	COG3128	pkhd-type hydroxylase
CHR26_RS02945	COG4774	siderophore transport
CHR26_RS02950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CHR26_RS02960	COG0436	Aminotransferase
CHR26_RS02965	COG1160	GTP binding
CHR26_RS02980	COG0124	histidyl-tRNA synthetase
CHR26_RS02985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHR26_RS03000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHR26_RS03005	COG0105	UTP biosynthetic process
CHR26_RS03015	COG0633	Ferredoxin
CHR26_RS03020	COG0443	Heat shock 70 kDa protein
CHR26_RS03025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CHR26_RS03030	COG0316	Belongs to the HesB IscA family
CHR26_RS03040	COG1104	cysteine desulfurase activity
CHR26_RS03050	COG1045	serine acetyltransferase
CHR26_RS03065	COG3134	Outer membrane lipoprotein
CHR26_RS03080	COG1862	Preprotein translocase
CHR26_RS03085	COG0343	queuine tRNA-ribosyltransferase activity
CHR26_RS03090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHR26_RS03115	COG3781	membrane
CHR26_RS03120	COG3639	organic phosphonate transmembrane transporter activity
CHR26_RS03125	COG3639	organic phosphonate transmembrane transporter activity
CHR26_RS03130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CHR26_RS03135	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CHR26_RS03140	COG0709	Synthesizes selenophosphate from selenide and ATP
CHR26_RS03145	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CHR26_RS03160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR26_RS03175	COG0727	PFAM Uncharacterised protein family (UPF0153)
CHR26_RS03185	COG0436	Aminotransferase
CHR26_RS03195	COG0109	protoheme IX farnesyltransferase activity
CHR26_RS03200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CHR26_RS03205	COG1845	cytochrome c oxidase, subunit III
CHR26_RS03210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR26_RS03215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR26_RS03225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CHR26_RS03230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR26_RS03230	COG1017	nitric oxide dioxygenase activity
CHR26_RS03235	COG3604	Transcriptional regulator
CHR26_RS03285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR26_RS03295	COG5002	protein histidine kinase activity
CHR26_RS03310	COG2203	Gaf domain
CHR26_RS03310	COG5001	Diguanylate cyclase
CHR26_RS03310	COG4251	negative regulation of phosphorylation
CHR26_RS03310	COG3706	GGDEF domain
CHR26_RS03320	COG3530	Putative quorum-sensing-regulated virulence factor
CHR26_RS03330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHR26_RS03330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHR26_RS03330	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CHR26_RS03335	COG1105	Belongs to the carbohydrate kinase PfkB family
CHR26_RS03340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR26_RS03340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHR26_RS03345	COG1609	Transcriptional regulator
CHR26_RS03350	COG0084	hydrolase, TatD family'
CHR26_RS03355	COG3725	Membrane protein required for beta-lactamase induction
CHR26_RS03360	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHR26_RS03375	COG0492	ferredoxin-NADP+ reductase activity
CHR26_RS03380	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CHR26_RS03470	COG0386	Belongs to the glutathione peroxidase family
CHR26_RS03485	COG0857	belongs to the CobB CobQ family
CHR26_RS03485	COG0280	phosphate acetyltransferase
CHR26_RS03490	COG2885	chlorophyll binding
CHR26_RS03495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR26_RS03530	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS03535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR26_RS03540	COG2813	Specifically methylates the guanine in position
CHR26_RS03545	COG2119	membrane
CHR26_RS03560	COG2135	peptidase activity
CHR26_RS03600	COG0579	oxidoreductase
CHR26_RS03615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CHR26_RS03620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHR26_RS03630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHR26_RS03635	COG1090	epimerase
CHR26_RS03640	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CHR26_RS03650	COG0789	Transcriptional regulator
CHR26_RS03655	COG0415	Belongs to the DNA photolyase family
CHR26_RS03670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHR26_RS03675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHR26_RS03685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHR26_RS03690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CHR26_RS03700	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CHR26_RS03705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CHR26_RS03715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHR26_RS03720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHR26_RS03725	COG0193	aminoacyl-tRNA hydrolase activity
CHR26_RS03745	COG1335	isochorismatase
CHR26_RS03770	COG3264	Mechanosensitive ion channel
CHR26_RS03770	COG1511	domain protein
CHR26_RS03775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR26_RS03775	COG2169	Transcriptional regulator
CHR26_RS03785	COG1595	DNA-templated transcription, initiation
CHR26_RS03800	COG2223	nitrite transmembrane transporter activity
CHR26_RS03830	COG0456	acetyltransferase
CHR26_RS03870	COG3045	CreA protein
CHR26_RS03875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHR26_RS03880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHR26_RS03885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHR26_RS03890	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHR26_RS03895	COG0142	geranyltranstransferase activity
CHR26_RS03900	COG2824	Alkylphosphonate utilization operon protein PhnA
CHR26_RS03910	COG0545	Peptidyl-prolyl cis-trans isomerase
CHR26_RS03920	COG2862	Uncharacterized protein family, UPF0114
CHR26_RS03930	COG1067	ATP-dependent peptidase activity
CHR26_RS03950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR26_RS03955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHR26_RS03960	COG0488	(ABC) transporter
CHR26_RS03980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHR26_RS04000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS04010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS04015	COG0765	amino acid transport
CHR26_RS04020	COG0039	L-malate dehydrogenase activity
CHR26_RS04075	COG0237	dephospho-CoA kinase activity
CHR26_RS04080	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CHR26_RS04110	COG1252	NADH dehydrogenase
CHR26_RS04140	COG0542	response to heat
CHR26_RS04165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS04195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHR26_RS04200	COG1047	Peptidyl-prolyl cis-trans
CHR26_RS04205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHR26_RS04210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHR26_RS04215	COG0196	riboflavin kinase activity
CHR26_RS04225	COG0268	Binds directly to 16S ribosomal RNA
CHR26_RS04230	COG3008	intermembrane lipid transfer
CHR26_RS04235	COG2995	paraquat-inducible protein a
CHR26_RS04240	COG2995	paraquat-inducible protein a
CHR26_RS04285	COG1309	transcriptional regulator
CHR26_RS04290	COG1739	Uncharacterized protein family UPF0029
CHR26_RS04295	COG0300	oxidoreductase activity
CHR26_RS04300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHR26_RS04315	COG2814	Major facilitator Superfamily
CHR26_RS04330	COG2217	Heavy metal translocating P-type atpase
CHR26_RS04345	COG2207	Transcriptional regulator
CHR26_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS04370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR26_RS04405	COG4953	penicillin-binding protein 1C
CHR26_RS04420	COG2373	Large extracellular alpha-helical protein
CHR26_RS04425	COG0534	Mate efflux family protein
CHR26_RS04435	COG1166	arginine decarboxylase activity
CHR26_RS04440	COG0023	Translation Initiation Factor
CHR26_RS04445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHR26_RS04475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHR26_RS04490	COG3284	Transcriptional regulator
CHR26_RS04495	COG3199	ATP-NAD kinase
CHR26_RS04500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR26_RS04505	COG0022	dehydrogenase e1 component
CHR26_RS04520	COG0702	epimerase
CHR26_RS04535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHR26_RS04540	COG3284	Transcriptional regulator
CHR26_RS04555	COG0531	amino acid
CHR26_RS04560	COG4303	Ethanolamine ammonia lyase large subunit
CHR26_RS04565	COG4302	ethanolamine ammonia-lyase activity
CHR26_RS04570	COG0456	acetyltransferase
CHR26_RS04575	COG0586	Pfam SNARE associated Golgi protein
CHR26_RS04580	COG3228	Belongs to the MtfA family
CHR26_RS04585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHR26_RS04645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR26_RS04690	COG0659	secondary active sulfate transmembrane transporter activity
CHR26_RS04695	COG0589	response to stress
CHR26_RS04730	COG2003	Belongs to the UPF0758 family
CHR26_RS04735	COG2026	Addiction module toxin, RelE StbE family
CHR26_RS04785	COG2819	hydrolase of the alpha beta superfamily
CHR26_RS04790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR26_RS04795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR26_RS04800	COG1722	exodeoxyribonuclease VII activity
CHR26_RS04805	COG0142	geranyltranstransferase activity
CHR26_RS04810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHR26_RS04815	COG4206	TonB-dependent receptor
CHR26_RS04820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHR26_RS04830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR26_RS04840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHR26_RS04845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CHR26_RS04850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHR26_RS04855	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHR26_RS04870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHR26_RS04870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHR26_RS04875	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHR26_RS04885	COG2264	protein methyltransferase activity
CHR26_RS04890	COG3118	belongs to the thioredoxin family
CHR26_RS04920	COG3047	cAMP biosynthetic process
CHR26_RS04925	COG2814	Major facilitator Superfamily
CHR26_RS04960	COG1115	amino acid carrier protein
CHR26_RS04965	COG0252	asparaginase activity
CHR26_RS04975	COG3276	selenocysteine insertion sequence binding
CHR26_RS04980	COG1921	L-seryl-tRNASec selenium transferase activity
CHR26_RS04990	COG3058	Necessary for formate dehydrogenase activity
CHR26_RS04995	COG2864	formate dehydrogenase
CHR26_RS05000	COG0437	4 iron, 4 sulfur cluster binding
CHR26_RS05010	COG4221	oxidoreductase activity
CHR26_RS05015	COG0730	response to heat
CHR26_RS05025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS05070	COG0629	single-stranded DNA binding
CHR26_RS05075	COG2814	Major facilitator Superfamily
CHR26_RS05080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHR26_RS05085	COG2193	ferroxidase activity
CHR26_RS05090	COG0753	catalase activity
CHR26_RS05095	COG0203	ribosomal protein L17
CHR26_RS05100	COG0202	RNA polymerase activity
CHR26_RS05105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHR26_RS05110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHR26_RS05115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHR26_RS05120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHR26_RS05130	COG0200	Binds to the 23S rRNA
CHR26_RS05135	COG1841	ribosomal large subunit assembly
CHR26_RS05140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHR26_RS05145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHR26_RS05150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHR26_RS05155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHR26_RS05160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHR26_RS05165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHR26_RS05170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHR26_RS05175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHR26_RS05180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHR26_RS05185	COG0255	Belongs to the universal ribosomal protein uL29 family
CHR26_RS05190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHR26_RS05195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHR26_RS05200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHR26_RS05205	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHR26_RS05210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHR26_RS05215	COG0089	rRNA binding
CHR26_RS05220	COG0088	Forms part of the polypeptide exit tunnel
CHR26_RS05225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHR26_RS05230	COG0051	transcription antitermination factor activity, RNA binding
CHR26_RS05235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHR26_RS05240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHR26_RS05245	COG0049	tRNA binding
CHR26_RS05250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHR26_RS05255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHR26_RS05260	COG0085	RNA polymerase activity
CHR26_RS05265	COG0222	ribosome binding
CHR26_RS05270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHR26_RS05275	COG0081	regulation of translation
CHR26_RS05280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHR26_RS05300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHR26_RS05325	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CHR26_RS05330	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHR26_RS05330	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHR26_RS05350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHR26_RS05360	COG0739	heme binding
CHR26_RS05365	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CHR26_RS05370	COG0316	Belongs to the HesB IscA family
CHR26_RS05375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHR26_RS05380	COG1981	membrane
CHR26_RS05385	COG2070	2-Nitropropane dioxygenase
CHR26_RS05390	COG0300	oxidoreductase activity
CHR26_RS05395	COG0537	adenosine 5'-monophosphoramidase activity
CHR26_RS05400	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CHR26_RS05410	COG1765	OsmC-like protein
CHR26_RS05425	COG0134	indole-3-glycerol-phosphate synthase activity
CHR26_RS05430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHR26_RS05435	COG0512	Glutamine amidotransferase of anthranilate synthase
CHR26_RS05440	COG3240	lipase activity
CHR26_RS05440	COG4625	pathogenesis
CHR26_RS05445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHR26_RS05450	COG0546	phosphoglycolate phosphatase activity
CHR26_RS05455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHR26_RS05465	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR26_RS05475	COG3842	ATPase activity
CHR26_RS05480	COG2197	response regulator
CHR26_RS05495	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CHR26_RS05500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CHR26_RS05505	COG3178	'Phosphotransferase
CHR26_RS05510	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CHR26_RS05515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR26_RS05520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHR26_RS05525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHR26_RS05535	COG2967	ApaG domain
CHR26_RS05540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR26_RS05545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR26_RS05550	COG2766	serine protein kinase
CHR26_RS05555	COG2718	Belongs to the UPF0229 family
CHR26_RS05560	COG2719	SpoVR family
CHR26_RS05565	COG0617	tRNA 3'-terminal CCA addition
CHR26_RS05575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHR26_RS05580	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHR26_RS05585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHR26_RS05590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR26_RS05595	COG0358	DNA primase activity
CHR26_RS05635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR26_RS05640	COG1025	Belongs to the peptidase M16 family
CHR26_RS05650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHR26_RS05655	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CHR26_RS05665	COG0535	radical SAM domain protein
CHR26_RS05685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR26_RS05690	COG0583	DNA-binding transcription factor activity
CHR26_RS05695	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS05700	COG3706	GGDEF domain
CHR26_RS05705	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS05725	COG2267	carboxylic ester hydrolase activity
CHR26_RS05730	COG0156	8-amino-7-oxononanoate synthase activity
CHR26_RS05735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHR26_RS05740	COG1040	competence protein
CHR26_RS05745	COG2005	Transcriptional regulator
CHR26_RS05745	COG3585	molybdate ion transport
CHR26_RS05750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CHR26_RS05765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CHR26_RS05775	COG1125	glycine betaine transport
CHR26_RS05775	COG0517	IMP dehydrogenase activity
CHR26_RS05780	COG2176	DNA-directed DNA polymerase activity
CHR26_RS05785	COG1595	DNA-templated transcription, initiation
CHR26_RS05790	COG3712	iron ion homeostasis
CHR26_RS05795	COG4774	siderophore transport
CHR26_RS05835	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS05850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CHR26_RS05870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR26_RS05880	COG4452	Inner membrane protein CreD
CHR26_RS05885	COG2205	protein histidine kinase activity
CHR26_RS05890	COG0745	RESPONSE REGULATOR receiver
CHR26_RS05900	COG0204	Acyl-transferase
CHR26_RS05905	COG0531	amino acid
CHR26_RS05920	COG1063	alcohol dehydrogenase
CHR26_RS05950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHR26_RS05960	COG0840	transmembrane signaling receptor activity
CHR26_RS05985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR26_RS05985	COG1017	nitric oxide dioxygenase activity
CHR26_RS05995	COG4638	Rieske (2fe-2S)
CHR26_RS06010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR26_RS06015	COG2181	nitrate reductase activity
CHR26_RS06015	COG0247	lactate metabolic process
CHR26_RS06020	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR26_RS06020	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS06050	COG3246	L-lysine catabolic process to acetate
CHR26_RS06055	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR26_RS06075	COG1760	l-serine dehydratase
CHR26_RS06085	COG4176	ABC-type proline glycine betaine transport system permease component
CHR26_RS06090	COG3448	diguanylate cyclase activity
CHR26_RS06090	COG4175	Glycine betaine
CHR26_RS06095	COG0107	imidazoleglycerol-phosphate synthase activity
CHR26_RS06100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHR26_RS06110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHR26_RS06115	COG0131	Imidazoleglycerol-phosphate dehydratase
CHR26_RS06120	COG2223	nitrite transmembrane transporter activity
CHR26_RS06135	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CHR26_RS06175	COG4215	(ABC) transporter
CHR26_RS06310	COG0069	glutamate synthase activity
CHR26_RS06330	COG2957	Belongs to the agmatine deiminase family
CHR26_RS06360	COG0494	nUDIX hydrolase
CHR26_RS06365	COG1011	Hydrolase
CHR26_RS06370	COG1652	LysM domain
CHR26_RS06375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHR26_RS06380	COG0243	molybdopterin cofactor binding
CHR26_RS06395	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CHR26_RS06400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHR26_RS06410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHR26_RS06415	COG4067	protein conserved in archaea
CHR26_RS06415	COG0189	ligase activity
CHR26_RS06420	COG0189	ligase activity
CHR26_RS06435	COG2183	response to ionizing radiation
CHR26_RS06445	COG2918	glutathione biosynthetic process
CHR26_RS06460	COG1116	anion transmembrane transporter activity
CHR26_RS06465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS06470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS06475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS06480	COG0431	NADPH-dependent FMN reductase
CHR26_RS06485	COG0450	alkyl hydroperoxide reductase
CHR26_RS06495	COG4521	taurine ABC transporter
CHR26_RS06500	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CHR26_RS06505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS06510	COG2175	clavaminate synthase activity
CHR26_RS06515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS06520	COG1045	serine acetyltransferase
CHR26_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS06530	COG0765	amino acid transport
CHR26_RS06535	COG1126	abc transporter atp-binding protein
CHR26_RS06560	COG1464	Belongs to the NlpA lipoprotein family
CHR26_RS06565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHR26_RS06570	COG2011	ABC-type metal ion transport system permease component
CHR26_RS06585	COG2199	diguanylate cyclase activity
CHR26_RS06595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR26_RS06600	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS06610	COG4771	TonB-dependent receptor
CHR26_RS06625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS06630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS06655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS06670	COG1053	succinate dehydrogenase
CHR26_RS06675	COG2188	Transcriptional regulator
CHR26_RS06690	COG0517	IMP dehydrogenase activity
CHR26_RS06690	COG0516	GMP reductase activity
CHR26_RS06720	COG1280	lysine exporter protein (LysE YggA)
CHR26_RS06730	COG0488	(ABC) transporter
CHR26_RS06755	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CHR26_RS06770	COG0181	hydroxymethylbilane synthase activity
CHR26_RS06780	COG0165	Argininosuccinate lyase
CHR26_RS06785	COG0625	glutathione transferase activity
CHR26_RS06800	COG0672	)-iron permease
CHR26_RS06825	COG1566	PFAM secretion protein HlyD family protein
CHR26_RS06835	COG1289	transmembrane transporter activity
CHR26_RS06855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS06870	COG2175	clavaminate synthase activity
CHR26_RS06890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS06895	COG3300	MHYT domain
CHR26_RS06895	COG5001	Diguanylate cyclase
CHR26_RS06905	COG1802	Transcriptional regulator
CHR26_RS06915	COG3712	iron ion homeostasis
CHR26_RS06975	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS06980	COG0583	DNA-binding transcription factor activity
CHR26_RS07000	COG0427	acetyl-CoA hydrolase
CHR26_RS07035	COG2851	Citrate transporter
CHR26_RS07040	COG0861	Integral membrane protein TerC family
CHR26_RS07045	COG1283	sodium-dependent phosphate transmembrane transporter activity
CHR26_RS07060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHR26_RS07065	COG1127	ABC transporter
CHR26_RS07080	COG0700	Nucleoside recognition
CHR26_RS07085	COG1301	dicarboxylic acid transport
CHR26_RS07110	COG2204	response regulator
CHR26_RS07115	COG5002	protein histidine kinase activity
CHR26_RS07120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHR26_RS07125	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHR26_RS07140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHR26_RS07150	COG3245	cytochrome
CHR26_RS07155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHR26_RS07175	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CHR26_RS07180	COG0735	belongs to the Fur family
CHR26_RS07185	COG1121	(ABC) transporter
CHR26_RS07190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHR26_RS07205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHR26_RS07210	COG2011	ABC-type metal ion transport system permease component
CHR26_RS07255	COG0109	protoheme IX farnesyltransferase activity
CHR26_RS07260	COG1612	heme a metabolic process
CHR26_RS07285	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CHR26_RS07290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR26_RS07295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR26_RS07310	COG0659	secondary active sulfate transmembrane transporter activity
CHR26_RS07325	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CHR26_RS07330	COG0339	signal peptide processing
CHR26_RS07335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHR26_RS07365	COG1764	response to oxidative stress
CHR26_RS07370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS07380	COG3360	Dodecin
CHR26_RS07395	COG0133	tryptophan synthase activity
CHR26_RS07400	COG0159	tryptophan synthase activity
CHR26_RS07420	COG3119	arylsulfatase activity
CHR26_RS07430	COG0659	secondary active sulfate transmembrane transporter activity
CHR26_RS07435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR26_RS07440	COG0408	coproporphyrinogen oxidase activity
CHR26_RS07460	COG0009	L-threonylcarbamoyladenylate synthase
CHR26_RS07465	COG0758	DNA mediated transformation
CHR26_RS07470	COG0242	peptide deformylase activity
CHR26_RS07475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHR26_RS07480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHR26_RS07485	COG0569	domain protein
CHR26_RS07500	COG2818	Glycosylase
CHR26_RS07505	COG0752	glycyl-tRNA synthetase alpha subunit
CHR26_RS07510	COG0751	glycine-tRNA ligase activity
CHR26_RS07515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHR26_RS07525	COG0477	Major facilitator Superfamily
CHR26_RS07545	COG1252	NADH dehydrogenase
CHR26_RS07645	COG0463	Glycosyl transferase, family 2
CHR26_RS07695	COG2194	sulfuric ester hydrolase activity
CHR26_RS07755	COG0187	DNA topoisomerase II activity
CHR26_RS07760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR26_RS07765	COG0592	DNA-directed DNA polymerase activity
CHR26_RS07770	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHR26_RS07775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHR26_RS07780	COG0594	ribonuclease P activity
CHR26_RS07785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHR26_RS07790	COG0706	membrane insertase activity
CHR26_RS07795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHR26_RS07800	COG0445	tRNA wobble uridine modification
CHR26_RS07805	COG0357	Ribosomal RNA small subunit methyltransferase G
CHR26_RS07810	COG1192	Involved in chromosome partitioning
CHR26_RS07815	COG1475	DNA binding
CHR26_RS07820	COG3312	ion transport
CHR26_RS07825	COG0356	it plays a direct role in the translocation of protons across the membrane
CHR26_RS07835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHR26_RS07840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHR26_RS07845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHR26_RS07850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHR26_RS07855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHR26_RS07860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHR26_RS07865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHR26_RS07870	COG1349	DNA-binding transcription factor activity
CHR26_RS07875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHR26_RS07980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR26_RS08000	COG0640	Transcriptional regulator
CHR26_RS08005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHR26_RS08010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHR26_RS08015	COG0431	NADPH-dependent FMN reductase
CHR26_RS08025	COG2072	flavoprotein involved in K transport
CHR26_RS08030	COG1247	-acetyltransferase
CHR26_RS08040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR26_RS08045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHR26_RS08050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR26_RS08060	COG1469	GTP cyclohydrolase I activity
CHR26_RS08080	COG0523	cobalamin synthesis protein
CHR26_RS08090	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CHR26_RS08095	COG1607	acyl-coa hydrolase
CHR26_RS08100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHR26_RS08100	COG4651	solute:proton antiporter activity
CHR26_RS08115	COG0210	DNA helicase
CHR26_RS08125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHR26_RS08140	COG0583	DNA-binding transcription factor activity
CHR26_RS08145	COG0439	Biotin carboxylase
CHR26_RS08150	COG5016	pyruvate
CHR26_RS08150	COG0511	ligase activity, forming carbon-carbon bonds
CHR26_RS08195	COG1027	Aspartate ammonia-lyase
CHR26_RS08200	COG0583	DNA-binding transcription factor activity
CHR26_RS08230	COG1607	acyl-coa hydrolase
CHR26_RS08235	COG0477	Major facilitator Superfamily
CHR26_RS08250	COG0581	inorganic phosphate transmembrane transporter activity
CHR26_RS08255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR26_RS08260	COG0704	Plays a role in the regulation of phosphate uptake
CHR26_RS08270	COG0739	heme binding
CHR26_RS08275	COG1253	flavin adenine dinucleotide binding
CHR26_RS08295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHR26_RS08300	COG3161	chorismate lyase activity
CHR26_RS08330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHR26_RS08335	COG0583	DNA-binding transcription factor activity
CHR26_RS08345	COG0848	biopolymer transport protein
CHR26_RS08370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR26_RS08375	COG1758	RNA polymerase activity
CHR26_RS08385	COG0174	glutamine synthetase
CHR26_RS08390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR26_RS08400	COG0194	GDP metabolic process
CHR26_RS08405	COG1561	YicC-like family, N-terminal region
CHR26_RS08410	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHR26_RS08415	COG0708	Exodeoxyribonuclease III
CHR26_RS08420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHR26_RS08425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHR26_RS08430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR26_RS08435	COG0756	dUTP diphosphatase activity
CHR26_RS08440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHR26_RS08445	COG2003	Belongs to the UPF0758 family
CHR26_RS08450	COG0747	negative chemotaxis
CHR26_RS08455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHR26_RS08460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHR26_RS08470	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS08480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR26_RS08485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS08495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS08510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS08530	COG0427	acetyl-CoA hydrolase
CHR26_RS08535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR26_RS08550	COG0534	Mate efflux family protein
CHR26_RS08555	COG0583	DNA-binding transcription factor activity
CHR26_RS08560	COG5383	Protein conserved in bacteria
CHR26_RS08565	COG0583	DNA-binding transcription factor activity
CHR26_RS08570	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS08575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS08585	COG1335	isochorismatase
CHR26_RS08600	COG0583	DNA-binding transcription factor activity
CHR26_RS08625	COG0606	chelatase, subunit chli
CHR26_RS08650	COG0347	Belongs to the P(II) protein family
CHR26_RS08655	COG0004	ammonium transporteR
CHR26_RS08665	COG0546	phosphoglycolate phosphatase activity
CHR26_RS08670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CHR26_RS08680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHR26_RS08685	COG0019	diaminopimelate decarboxylase activity
CHR26_RS08700	COG1965	Belongs to the frataxin family
CHR26_RS08710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR26_RS08715	COG3072	Adenylate cyclase
CHR26_RS08720	COG1671	Belongs to the UPF0178 family
CHR26_RS08725	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CHR26_RS08740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHR26_RS08745	COG0248	Ppx GppA phosphatase
CHR26_RS08760	COG3657	addiction module killer protein
CHR26_RS08770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHR26_RS08795	COG0842	Transport permease protein
CHR26_RS08800	COG1129	ABC transporter
CHR26_RS08800	COG0842	Transport permease protein
CHR26_RS08805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS08815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHR26_RS08835	COG3079	Belongs to the UPF0149 family
CHR26_RS08840	COG0006	proline dipeptidase activity
CHR26_RS08845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR26_RS08855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR26_RS08865	COG1178	ABC-type Fe3 transport system permease component
CHR26_RS08870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR26_RS08875	COG0509	glycine decarboxylation via glycine cleavage system
CHR26_RS08880	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR26_RS08880	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR26_RS08890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR26_RS08900	COG1522	sequence-specific DNA binding
CHR26_RS08910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR26_RS08915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CHR26_RS08915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHR26_RS08920	COG0174	glutamine synthetase
CHR26_RS08930	COG0174	glutamine synthetase
CHR26_RS08950	COG3842	ATPase activity
CHR26_RS08955	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR26_RS08960	COG1177	transmembrane transport
CHR26_RS08985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR26_RS08995	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CHR26_RS09005	COG4208	sulfate ABC transporter
CHR26_RS09010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHR26_RS09040	COG3829	transcription factor binding
CHR26_RS09050	COG0765	amino acid transport
CHR26_RS09055	COG0765	amino acid transport
CHR26_RS09060	COG1126	abc transporter atp-binding protein
CHR26_RS09065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS09100	COG1683	Conserved Protein
CHR26_RS09105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS09115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR26_RS09120	COG0277	FAD linked oxidase domain protein
CHR26_RS09125	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR26_RS09130	COG3204	pilus organization
CHR26_RS09135	COG3204	pilus organization
CHR26_RS09140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CHR26_RS09145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHR26_RS09160	COG0494	nUDIX hydrolase
CHR26_RS09165	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CHR26_RS09175	COG0730	response to heat
CHR26_RS09180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHR26_RS09185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHR26_RS09190	COG0789	Transcriptional regulator
CHR26_RS09205	COG3842	ATPase activity
CHR26_RS09210	COG1178	ABC-type Fe3 transport system permease component
CHR26_RS09215	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR26_RS09220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHR26_RS09235	COG1823	symporter activity
CHR26_RS09245	COG0129	dihydroxy-acid dehydratase activity
CHR26_RS09255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CHR26_RS09265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHR26_RS09270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHR26_RS09275	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHR26_RS09305	COG0612	Peptidase, M16
CHR26_RS09310	COG0742	ribosomal rna small subunit methyltransferase
CHR26_RS09315	COG0612	Peptidase, M16
CHR26_RS09320	COG0612	Peptidase, M16
CHR26_RS09330	COG0552	protein localization to endoplasmic reticulum
CHR26_RS09335	COG2884	Cell division ATP-binding protein ftsE
CHR26_RS09340	COG2177	Part of the ABC transporter FtsEX involved in
CHR26_RS09350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR26_RS09355	COG2363	Small membrane protein
CHR26_RS09360	COG2104	thiamine diphosphate biosynthetic process
CHR26_RS09360	COG2022	thiamine diphosphate biosynthetic process
CHR26_RS09365	COG2022	thiamine diphosphate biosynthetic process
CHR26_RS09370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHR26_RS09380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHR26_RS09385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHR26_RS09395	COG2813	Specifically methylates the guanine in position
CHR26_RS09395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR26_RS09400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR26_RS09425	COG0791	NLP P60 protein
CHR26_RS09440	COG0018	arginyl-trna synthetase
CHR26_RS09445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHR26_RS09450	COG0254	rRNA binding
CHR26_RS09460	COG0281	malic enzyme
CHR26_RS09470	COG3344	reverse transcriptase
CHR26_RS09495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHR26_RS09500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHR26_RS09515	COG0070	glutamate synthase
CHR26_RS09515	COG0069	glutamate synthase activity
CHR26_RS09515	COG0067	glutamate synthase
CHR26_RS09520	COG0493	'glutamate synthase
CHR26_RS09525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHR26_RS09535	COG2814	Major facilitator Superfamily
CHR26_RS09540	COG0583	DNA-binding transcription factor activity
CHR26_RS09545	COG1192	Involved in chromosome partitioning
CHR26_RS09550	COG3118	belongs to the thioredoxin family
CHR26_RS09555	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHR26_RS09560	COG1196	nuclear chromosome segregation
CHR26_RS09560	COG3264	Mechanosensitive ion channel
CHR26_RS09565	COG3263	regulation of cellular component size
CHR26_RS09575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CHR26_RS09580	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS09585	COG1309	transcriptional regulator
CHR26_RS09590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS09595	COG2861	carbohydrate metabolic process
CHR26_RS09600	COG0793	Belongs to the peptidase S41A family
CHR26_RS09605	COG4942	peptidase
CHR26_RS09610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CHR26_RS09615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR26_RS09625	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CHR26_RS09630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHR26_RS09645	COG3852	Histidine kinase
CHR26_RS09660	COG0301	tRNA thio-modification
CHR26_RS09660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR26_RS09665	COG1217	gtp-binding protein TYPA
CHR26_RS09675	COG0058	SHG alpha-glucan phosphorylase activity
CHR26_RS09680	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CHR26_RS09705	COG0402	S-adenosylhomocysteine deaminase activity
CHR26_RS09710	COG2188	Transcriptional regulator
CHR26_RS09720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR26_RS09725	COG2986	histidine ammonia-lyase
CHR26_RS09735	COG1228	amidohydrolase
CHR26_RS09755	COG1490	D-aminoacyl-tRNA deacylase activity
CHR26_RS09760	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CHR26_RS09765	COG2943	transferase activity, transferring hexosyl groups
CHR26_RS09775	COG0765	amino acid transport
CHR26_RS09780	COG1126	abc transporter atp-binding protein
CHR26_RS09785	COG0840	transmembrane signaling receptor activity
CHR26_RS09790	COG0840	transmembrane signaling receptor activity
CHR26_RS09810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR26_RS09815	COG0140	phosphoribosyl-ATP diphosphatase activity
CHR26_RS09820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHR26_RS09825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CHR26_RS09835	COG2226	methyltransferase
CHR26_RS09885	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHR26_RS09890	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHR26_RS09895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHR26_RS09900	COG0540	Belongs to the ATCase OTCase family
CHR26_RS09905	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CHR26_RS09910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHR26_RS09915	COG1678	Uncharacterized ACR, COG1678
CHR26_RS09925	COG0189	ligase activity
CHR26_RS09950	COG0643	Histidine kinase
CHR26_RS09950	COG0784	Response regulator, receiver
CHR26_RS09950	COG2198	Histidine kinase
CHR26_RS09960	COG1272	protein, Hemolysin III
CHR26_RS09965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHR26_RS09985	COG3038	cytochrome b561
CHR26_RS09990	COG2353	YceI-like domain
CHR26_RS09995	COG0513	Belongs to the DEAD box helicase family
CHR26_RS10010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CHR26_RS10015	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CHR26_RS10055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHR26_RS10060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHR26_RS10065	COG0640	Transcriptional regulator
CHR26_RS10080	COG0126	phosphoglycerate kinase activity
CHR26_RS10105	COG1451	nucleotide metabolic process
CHR26_RS10115	COG2153	protein acetylation
CHR26_RS10120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS10125	COG1289	transmembrane transporter activity
CHR26_RS10130	COG2081	HI0933 family
CHR26_RS10135	COG0513	Belongs to the DEAD box helicase family
CHR26_RS10140	COG0477	Major facilitator Superfamily
CHR26_RS10145	COG0312	modulator of DNA gyrase
CHR26_RS10155	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS10170	COG0506	proline dehydrogenase activity
CHR26_RS10170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CHR26_RS10170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CHR26_RS10175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR26_RS10185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CHR26_RS10190	COG2192	nodulation
CHR26_RS10195	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS10220	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS10235	COG1132	(ABC) transporter
CHR26_RS10240	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CHR26_RS10240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHR26_RS10250	COG0667	Aldo Keto reductase
CHR26_RS10275	COG1519	Transferase
CHR26_RS10280	COG1538	Outer membrane efflux protein
CHR26_RS10285	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHR26_RS10300	COG0494	nUDIX hydrolase
CHR26_RS10310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHR26_RS10315	COG3150	esterase
CHR26_RS10330	COG3577	Aspartyl protease
CHR26_RS10350	COG3830	Belongs to the UPF0237 family
CHR26_RS10350	COG0560	Phosphoserine phosphatase
CHR26_RS10365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CHR26_RS10375	COG1162	GTPase activity
CHR26_RS10380	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CHR26_RS10385	COG2860	membrane
CHR26_RS10395	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHR26_RS10395	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHR26_RS10400	COG0802	atpase or kinase
CHR26_RS10405	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHR26_RS10410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHR26_RS10415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHR26_RS10420	COG1923	regulation of RNA biosynthetic process
CHR26_RS10425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHR26_RS10430	COG0330	HflC and HflK could
CHR26_RS10435	COG0330	HflC and HflK could
CHR26_RS10440	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHR26_RS10445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHR26_RS10450	COG0840	transmembrane signaling receptor activity
CHR26_RS10455	COG1178	ABC-type Fe3 transport system permease component
CHR26_RS10460	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR26_RS10475	COG0557	exoribonuclease II activity
CHR26_RS10480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR26_RS10485	COG0360	Binds together with S18 to 16S ribosomal RNA
CHR26_RS10490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHR26_RS10500	COG0359	binds to the 23S rRNA
CHR26_RS10505	COG0305	Participates in initiation and elongation during chromosome replication
CHR26_RS10510	COG5265	(ABC) transporter
CHR26_RS10515	COG1032	radical SAM domain protein
CHR26_RS10530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CHR26_RS10535	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHR26_RS10565	COG4221	oxidoreductase activity
CHR26_RS10585	COG2982	Protein involved in outer membrane biogenesis
CHR26_RS10605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CHR26_RS10610	COG0697	spore germination
CHR26_RS10630	COG0443	Heat shock 70 kDa protein
CHR26_RS10635	COG0484	heat shock protein binding
CHR26_RS10640	COG0789	Transcriptional regulator
CHR26_RS10655	COG0411	ABC transporter
CHR26_RS10675	COG1113	amino acid transport
CHR26_RS10685	COG4774	siderophore transport
CHR26_RS10705	COG0330	HflC and HflK could
CHR26_RS10725	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CHR26_RS10740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR26_RS10775	COG2095	MarC family integral membrane protein
CHR26_RS10785	COG0151	Belongs to the GarS family
CHR26_RS10790	COG0138	bifunctional purine biosynthesis protein purh
CHR26_RS10800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHR26_RS10810	COG2264	protein methyltransferase activity
CHR26_RS10825	COG1346	cytolysis
CHR26_RS10835	COG0586	Pfam SNARE associated Golgi protein
CHR26_RS10840	COG2094	Belongs to the DNA glycosylase MPG family
CHR26_RS10845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHR26_RS10850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHR26_RS10860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHR26_RS10865	COG0768	penicillin binding
CHR26_RS10870	COG0772	Belongs to the SEDS family
CHR26_RS10875	COG2951	lytic endotransglycosylase activity
CHR26_RS10885	COG1686	Belongs to the peptidase S11 family
CHR26_RS10890	COG2921	Belongs to the UPF0250 family
CHR26_RS10895	COG0321	lipoyl(octanoyl) transferase activity
CHR26_RS10900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHR26_RS10905	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHR26_RS10910	COG2951	lytic endotransglycosylase activity
CHR26_RS10930	COG0495	leucyl-tRNA aminoacylation
CHR26_RS10945	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CHR26_RS10950	COG4535	Mg2 and Co2 transporter CorC
CHR26_RS10955	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHR26_RS10960	COG1702	phosphate starvation-inducible protein PhoH
CHR26_RS10975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHR26_RS10980	COG0352	thiamine-phosphate diphosphorylase activity
CHR26_RS10985	COG0351	phosphomethylpyrimidine kinase
CHR26_RS10990	COG4999	Histidine kinase
CHR26_RS10990	COG3850	Histidine kinase
CHR26_RS10990	COG2205	protein histidine kinase activity
CHR26_RS10990	COG3437	response regulator, receiver
CHR26_RS11015	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS11020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHR26_RS11035	COG1522	sequence-specific DNA binding
CHR26_RS11055	COG1643	Atp-dependent helicase
CHR26_RS11065	COG3416	Protein conserved in bacteria
CHR26_RS11075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHR26_RS11080	COG0697	spore germination
CHR26_RS11085	COG0513	Belongs to the DEAD box helicase family
CHR26_RS11095	COG0123	including yeast histone deacetylase and acetoin utilization protein
CHR26_RS11110	COG1946	Acyl-CoA thioesterase
CHR26_RS11120	COG3321	synthase
CHR26_RS11120	COG0604	alcohol dehydrogenase
CHR26_RS11225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR26_RS11385	COG4774	siderophore transport
CHR26_RS11395	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR26_RS11395	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS11400	COG0006	proline dipeptidase activity
CHR26_RS11405	COG1126	abc transporter atp-binding protein
CHR26_RS11410	COG0765	amino acid transport
CHR26_RS11455	COG0582	viral genome integration into host DNA
CHR26_RS11480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CHR26_RS11535	COG1484	DNA-dependent DNA replication
CHR26_RS11540	COG0305	Participates in initiation and elongation during chromosome replication
CHR26_RS11665	COG1304	FMN binding
CHR26_RS11670	COG1620	l-lactate permease
CHR26_RS11680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHR26_RS11690	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHR26_RS11695	COG0735	belongs to the Fur family
CHR26_RS11700	COG0497	DNA recombination
CHR26_RS11705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHR26_RS11710	COG0443	Heat shock 70 kDa protein
CHR26_RS11715	COG0484	heat shock protein binding
CHR26_RS11720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHR26_RS11725	COG0505	Belongs to the CarA family
CHR26_RS11730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHR26_RS11735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR26_RS11750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CHR26_RS11760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHR26_RS11765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR26_RS11770	COG0149	triose-phosphate isomerase activity
CHR26_RS11775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHR26_RS11790	COG0779	Required for maturation of 30S ribosomal subunits
CHR26_RS11795	COG0195	Participates in both transcription termination and antitermination
CHR26_RS11800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHR26_RS11805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHR26_RS11810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHR26_RS11815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHR26_RS11820	COG1185	polyribonucleotide nucleotidyltransferase activity
CHR26_RS11825	COG2823	Periplasmic or secreted lipoprotein
CHR26_RS11850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR26_RS11855	COG0166	Belongs to the GPI family
CHR26_RS11860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHR26_RS11865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHR26_RS11875	COG0617	tRNA 3'-terminal CCA addition
CHR26_RS11885	COG4191	Histidine kinase
CHR26_RS11895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHR26_RS11905	COG0436	Aminotransferase
CHR26_RS11910	COG1489	DNA binding
CHR26_RS11920	COG4558	Periplasmic binding protein
CHR26_RS11925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR26_RS11930	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CHR26_RS11950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR26_RS11960	COG3098	single-species biofilm formation
CHR26_RS11965	COG0028	Belongs to the TPP enzyme family
CHR26_RS11975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHR26_RS11980	COG1183	phosphatidylcholine synthase activity
CHR26_RS11985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR26_RS11990	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CHR26_RS12020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CHR26_RS12025	COG1074	ATP-dependent DNA helicase activity
CHR26_RS12030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR26_RS12040	COG2199	diguanylate cyclase activity
CHR26_RS12045	COG3047	cAMP biosynthetic process
CHR26_RS12045	COG2885	chlorophyll binding
CHR26_RS12070	COG4589	Belongs to the CDS family
CHR26_RS12085	COG0671	phosphoesterase, PA-phosphatase related
CHR26_RS12085	COG2453	phosphatase
CHR26_RS12090	COG2267	carboxylic ester hydrolase activity
CHR26_RS12095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHR26_RS12100	COG0583	DNA-binding transcription factor activity
CHR26_RS12115	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHR26_RS12120	COG0583	DNA-binding transcription factor activity
CHR26_RS12130	COG0840	transmembrane signaling receptor activity
CHR26_RS12135	COG2321	neutral zinc metallopeptidase
CHR26_RS12140	COG3485	protocatechuate 3,4-dioxygenase
CHR26_RS12145	COG3485	protocatechuate 3,4-dioxygenase
CHR26_RS12150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR26_RS12155	COG2252	PERMEase
CHR26_RS12165	COG1271	oxidase subunit
CHR26_RS12170	COG1294	oxidase, subunit
CHR26_RS12180	COG2813	Specifically methylates the guanine in position
CHR26_RS12185	COG2197	response regulator
CHR26_RS12195	COG1970	mechanosensitive ion channel activity
CHR26_RS12205	COG2233	PERMEase
CHR26_RS12215	COG1966	Carbon starvation protein
CHR26_RS12220	COG2879	small protein
CHR26_RS12225	COG0523	cobalamin synthesis protein
CHR26_RS12235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHR26_RS12255	COG2957	Belongs to the agmatine deiminase family
CHR26_RS12280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHR26_RS12310	COG0789	Transcriptional regulator
CHR26_RS12320	COG1366	Belongs to the anti-sigma-factor antagonist family
CHR26_RS12330	COG0583	DNA-binding transcription factor activity
CHR26_RS12335	COG1380	Effector of murein hydrolase LrgA
CHR26_RS12340	COG1346	cytolysis
CHR26_RS12345	COG0596	Alpha beta hydrolase
CHR26_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS12360	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CHR26_RS12450	COG4964	Belongs to the GSP D family
CHR26_RS12515	COG2207	Transcriptional regulator
CHR26_RS12515	COG3708	Transcriptional regulator
CHR26_RS12520	COG0697	spore germination
CHR26_RS12525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR26_RS12530	COG0583	DNA-binding transcription factor activity
CHR26_RS12550	COG1566	PFAM secretion protein HlyD family protein
CHR26_RS12585	COG0300	oxidoreductase activity
CHR26_RS12595	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CHR26_RS12595	COG0662	Cupin 2, conserved barrel domain protein
CHR26_RS12610	COG1696	Membrane protein involved in D-alanine export
CHR26_RS12630	COG3420	alginic acid biosynthetic process
CHR26_RS12640	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CHR26_RS12645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS12655	COG1215	transferase activity, transferring glycosyl groups
CHR26_RS12660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHR26_RS12665	COG3022	response to hydroperoxide
CHR26_RS12675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CHR26_RS12680	COG0315	cyclic pyranopterin monophosphate synthase activity
CHR26_RS12685	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CHR26_RS12700	COG0513	Belongs to the DEAD box helicase family
CHR26_RS12705	COG0400	carboxylic ester hydrolase activity
CHR26_RS12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS12715	COG4597	amino acid ABC transporter
CHR26_RS12720	COG0765	amino acid transport
CHR26_RS12725	COG1126	abc transporter atp-binding protein
CHR26_RS12730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR26_RS12745	COG0175	sulfate reduction
CHR26_RS12765	COG1522	sequence-specific DNA binding
CHR26_RS12785	COG0180	Tryptophanyl-tRNA synthetase
CHR26_RS12790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHR26_RS12800	COG0667	Aldo Keto reductase
CHR26_RS12805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHR26_RS12810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHR26_RS12815	COG0723	plastoquinol--plastocyanin reductase activity
CHR26_RS12820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CHR26_RS12825	COG2857	Cytochrome c1
CHR26_RS12830	COG0625	glutathione transferase activity
CHR26_RS12835	COG2969	positive regulation of protein catabolic process
CHR26_RS12845	COG2823	Periplasmic or secreted lipoprotein
CHR26_RS12850	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CHR26_RS12855	COG0792	nuclease activity
CHR26_RS12860	COG3107	peptidoglycan biosynthetic process
CHR26_RS12875	COG2001	Belongs to the MraZ family
CHR26_RS12880	COG0275	rRNA processing
CHR26_RS12895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHR26_RS12900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHR26_RS12905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHR26_RS12910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHR26_RS12915	COG0772	Belongs to the SEDS family
CHR26_RS12920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR26_RS12925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHR26_RS12930	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHR26_RS12945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHR26_RS12950	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CHR26_RS12970	COG0653	protein targeting
CHR26_RS12975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHR26_RS12990	COG0352	thiamine-phosphate diphosphorylase activity
CHR26_RS12995	COG2096	Adenosyltransferase
CHR26_RS13010	COG1666	GTP binding
CHR26_RS13015	COG0668	transmembrane transport
CHR26_RS13045	COG3030	protein affecting phage T7 exclusion by the F plasmid
CHR26_RS13050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHR26_RS13055	COG0459	protein refolding
CHR26_RS13070	COG0642	Histidine kinase
CHR26_RS13080	COG3642	lipopolysaccharide core region biosynthetic process
CHR26_RS13090	COG2814	Major facilitator Superfamily
CHR26_RS13095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR26_RS13100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS13145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHR26_RS13155	COG0583	DNA-binding transcription factor activity
CHR26_RS13160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR26_RS13175	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS13225	COG0693	protein deglycase activity
CHR26_RS13255	COG0469	pyruvate kinase activity
CHR26_RS13270	COG2925	Exonuclease
CHR26_RS13280	COG0788	formyltetrahydrofolate deformylase activity
CHR26_RS13300	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS13300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR26_RS13305	COG0840	transmembrane signaling receptor activity
CHR26_RS13310	COG0433	COG0433 Predicted ATPase
CHR26_RS13315	COG0306	phosphate transporter
CHR26_RS13330	COG1414	Transcriptional regulator
CHR26_RS13335	COG2814	Major facilitator Superfamily
CHR26_RS13340	COG0183	Belongs to the thiolase family
CHR26_RS13345	COG0477	Major facilitator Superfamily
CHR26_RS13350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHR26_RS13355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR26_RS13360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR26_RS13385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR26_RS13390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS13395	COG1309	transcriptional regulator
CHR26_RS13400	COG0477	Major facilitator Superfamily
CHR26_RS13405	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CHR26_RS13420	COG2910	NAD(P)H-binding
CHR26_RS13425	COG0583	DNA-binding transcription factor activity
CHR26_RS13435	COG2207	Transcriptional regulator
CHR26_RS13465	COG0477	Major facilitator Superfamily
CHR26_RS13475	COG4191	Histidine kinase
CHR26_RS13520	COG2267	carboxylic ester hydrolase activity
CHR26_RS13550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHR26_RS13555	COG0737	Belongs to the 5'-nucleotidase family
CHR26_RS13560	COG3180	Ammonia monooxygenase
CHR26_RS13600	COG0354	folic acid binding
CHR26_RS13605	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CHR26_RS13635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR26_RS13640	COG0481	GTPase activity
CHR26_RS13645	COG0681	Belongs to the peptidase S26 family
CHR26_RS13650	COG0571	ribonuclease III activity
CHR26_RS13655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHR26_RS13660	COG1381	Involved in DNA repair and RecF pathway recombination
CHR26_RS13665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CHR26_RS13685	COG0500	methyltransferase
CHR26_RS13690	COG2226	methyltransferase
CHR26_RS13710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHR26_RS13725	COG4206	TonB-dependent receptor
CHR26_RS13730	COG4628	conserved protein (DUF2132)
CHR26_RS13745	COG2375	cellular response to nickel ion
CHR26_RS13750	COG1695	Transcriptional regulator
CHR26_RS13760	COG1113	amino acid transport
CHR26_RS13765	COG0069	glutamate synthase activity
CHR26_RS13770	COG1201	RNA secondary structure unwinding
CHR26_RS13775	COG0494	nUDIX hydrolase
CHR26_RS13780	COG0583	DNA-binding transcription factor activity
CHR26_RS13785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR26_RS13805	COG1126	abc transporter atp-binding protein
CHR26_RS13810	COG0765	amino acid transport
CHR26_RS13815	COG0765	amino acid transport
CHR26_RS13840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR26_RS13850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHR26_RS13855	COG3842	ATPase activity
CHR26_RS13860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR26_RS13865	COG0243	molybdopterin cofactor binding
CHR26_RS13870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CHR26_RS13890	COG0450	alkyl hydroperoxide reductase
CHR26_RS13895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHR26_RS13900	COG0418	dihydroorotase activity
CHR26_RS13910	COG0137	argininosuccinate synthase activity
CHR26_RS13920	COG2197	response regulator
CHR26_RS13925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHR26_RS13935	COG4659	FMN binding
CHR26_RS13950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR26_RS13950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR26_RS13955	COG0489	protein tyrosine kinase activity
CHR26_RS13960	COG1278	Cold shock
CHR26_RS13965	COG0717	Belongs to the dCTP deaminase family
CHR26_RS13980	COG1201	RNA secondary structure unwinding
CHR26_RS13990	COG1793	dna ligase
CHR26_RS13995	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHR26_RS13995	COG1793	dna ligase
CHR26_RS14000	COG2366	antibiotic biosynthetic process
CHR26_RS14005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS14010	COG1045	serine acetyltransferase
CHR26_RS14015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHR26_RS14020	COG2814	Major facilitator Superfamily
CHR26_RS14030	COG0653	protein targeting
CHR26_RS14040	COG3012	SEC-C Motif Domain Protein
CHR26_RS14110	COG1199	ATP-dependent helicase activity
CHR26_RS14125	COG2885	chlorophyll binding
CHR26_RS14130	COG0259	pyridoxamine-phosphate oxidase activity
CHR26_RS14145	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHR26_RS14150	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CHR26_RS14195	COG2084	Dehydrogenase
CHR26_RS14205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR26_RS14220	COG1289	transmembrane transporter activity
CHR26_RS14240	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS14245	COG0583	DNA-binding transcription factor activity
CHR26_RS14255	COG5001	Diguanylate cyclase
CHR26_RS14260	COG3706	GGDEF domain
CHR26_RS14270	COG2116	formate transmembrane transporter activity
CHR26_RS14315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR26_RS14325	COG0252	asparaginase activity
CHR26_RS14330	COG3012	SEC-C Motif Domain Protein
CHR26_RS14330	COG3318	Belongs to the UPF0149 family
CHR26_RS14335	COG0625	glutathione transferase activity
CHR26_RS14340	COG1017	nitric oxide dioxygenase activity
CHR26_RS14340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR26_RS14345	COG0583	DNA-binding transcription factor activity
CHR26_RS14350	COG2271	Major facilitator Superfamily
CHR26_RS14375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR26_RS14385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR26_RS14395	COG3077	Addiction module antitoxin, RelB DinJ family
CHR26_RS14400	COG2026	Addiction module toxin, RelE StbE family
CHR26_RS14415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR26_RS14420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHR26_RS14420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR26_RS14425	COG0745	RESPONSE REGULATOR receiver
CHR26_RS14430	COG2205	protein histidine kinase activity
CHR26_RS14460	COG1301	dicarboxylic acid transport
CHR26_RS14470	COG4807	Protein conserved in bacteria
CHR26_RS14480	COG0519	Catalyzes the synthesis of GMP from XMP
CHR26_RS14510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHR26_RS14515	COG3158	transport of potassium into the cell
CHR26_RS14545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR26_RS14555	COG0442	prolyl-tRNA aminoacylation
CHR26_RS14570	COG2900	Belongs to the SlyX family
CHR26_RS14580	COG0783	Belongs to the Dps family
CHR26_RS14595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHR26_RS14600	COG0217	transcriptional regulatory protein
CHR26_RS14610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CHR26_RS14615	COG0632	four-way junction helicase activity
CHR26_RS14620	COG2255	four-way junction helicase activity
CHR26_RS14625	COG0824	Thioesterase
CHR26_RS14645	COG0823	Involved in the tonB-independent uptake of proteins
CHR26_RS14650	COG2885	chlorophyll binding
CHR26_RS14655	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CHR26_RS14660	COG0602	queuosine metabolic process
CHR26_RS14665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHR26_RS14675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CHR26_RS14695	COG3609	addiction module antidote protein, CC2985 family
CHR26_RS14805	COG1074	ATP-dependent DNA helicase activity
CHR26_RS14840	COG0653	protein targeting
CHR26_RS14855	COG2135	peptidase activity
CHR26_RS14955	COG0589	response to stress
CHR26_RS14960	COG0659	secondary active sulfate transmembrane transporter activity
CHR26_RS15025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR26_RS15070	COG2169	Transcriptional regulator
CHR26_RS15070	COG1917	Cupin 2, conserved barrel domain protein
CHR26_RS15130	COG1238	metal cluster binding
CHR26_RS15155	COG2814	Major facilitator Superfamily
CHR26_RS15175	COG0642	Histidine kinase
CHR26_RS15185	COG3039	Transposase
CHR26_RS15235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR26_RS15245	COG0789	Transcriptional regulator
CHR26_RS15280	COG4644	lycopene metabolic process
CHR26_RS15345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR26_RS15355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHR26_RS15395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CHR26_RS15420	COG3081	Nucleoid-associated protein
CHR26_RS15440	COG0305	Participates in initiation and elongation during chromosome replication
CHR26_RS15480	COG0840	transmembrane signaling receptor activity
CHR26_RS15485	COG0531	amino acid
CHR26_RS15495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHR26_RS15520	COG0425	Belongs to the sulfur carrier protein TusA family
CHR26_RS15530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHR26_RS15540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR26_RS15545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CHR26_RS15550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHR26_RS15555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHR26_RS15595	COG5532	Uncharacterized conserved protein (DUF2303)
CHR26_RS15775	COG3179	chitinase
CHR26_RS15885	COG1595	DNA-templated transcription, initiation
CHR26_RS15890	COG0579	oxidoreductase
CHR26_RS15895	COG0640	Transcriptional regulator
CHR26_RS15900	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS15915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR26_RS15920	COG3938	Belongs to the proline racemase family
CHR26_RS15925	COG0531	amino acid
CHR26_RS15935	COG0583	DNA-binding transcription factor activity
CHR26_RS15940	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHR26_RS15950	COG3781	membrane
CHR26_RS15955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHR26_RS15970	COG1522	sequence-specific DNA binding
CHR26_RS15975	COG0626	cystathionine gamma-synthase activity
CHR26_RS15995	COG3100	YcgL domain-containing protein
CHR26_RS16015	COG2983	Belongs to the UPF0260 family
CHR26_RS16055	COG0121	glutamine amidotransferase
CHR26_RS16070	COG2814	Major facilitator Superfamily
CHR26_RS16075	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR26_RS16080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHR26_RS16085	COG1984	allophanate hydrolase subunit 2
CHR26_RS16105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHR26_RS16135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CHR26_RS16155	COG3420	alginic acid biosynthetic process
CHR26_RS16165	COG1295	ribonuclease BN
CHR26_RS16170	COG0242	peptide deformylase activity
CHR26_RS16190	COG3795	YCII-related domain
CHR26_RS16200	COG4941	Belongs to the sigma-70 factor family
CHR26_RS16205	COG2030	dehydratase
CHR26_RS16210	COG2267	carboxylic ester hydrolase activity
CHR26_RS16215	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS16220	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS16225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS16230	COG0174	glutamine synthetase
CHR26_RS16235	COG1643	Atp-dependent helicase
CHR26_RS16245	COG2188	Transcriptional regulator
CHR26_RS16255	COG1132	(ABC) transporter
CHR26_RS16265	COG2267	carboxylic ester hydrolase activity
CHR26_RS16280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHR26_RS16290	COG0679	Auxin Efflux Carrier
CHR26_RS16295	COG0668	transmembrane transport
CHR26_RS16300	COG0513	Belongs to the DEAD box helicase family
CHR26_RS16310	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR26_RS16315	COG3657	addiction module killer protein
CHR26_RS16325	COG0697	spore germination
CHR26_RS16335	COG0583	DNA-binding transcription factor activity
CHR26_RS16355	COG0840	transmembrane signaling receptor activity
CHR26_RS16370	COG2832	Protein of unknown function (DUF454)
CHR26_RS16385	COG0514	ATP-dependent DNA helicase (RecQ)
CHR26_RS16395	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHR26_RS16410	COG2207	Transcriptional regulator
CHR26_RS16430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR26_RS16435	COG0778	Nitroreductase
CHR26_RS16450	COG0745	RESPONSE REGULATOR receiver
CHR26_RS16455	COG2350	Protein conserved in bacteria
CHR26_RS16460	COG2917	probably involved in intracellular septation
CHR26_RS16465	COG0613	PHP domain protein
CHR26_RS16470	COG0009	L-threonylcarbamoyladenylate synthase
CHR26_RS16480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHR26_RS16490	COG1113	amino acid transport
CHR26_RS16500	COG0247	lactate metabolic process
CHR26_RS16500	COG0277	FAD linked oxidase domain protein
CHR26_RS16510	COG2154	pterin-4-alpha-carbinolamine dehydratase
CHR26_RS16535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR26_RS16545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS16570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR26_RS16585	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS16590	COG3724	N-succinylarginine dihydrolase activity
CHR26_RS16600	COG2988	succinylglutamate desuccinylase activity
CHR26_RS16605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHR26_RS16610	COG0527	aspartate kinase activity
CHR26_RS16615	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CHR26_RS16640	COG2239	Acts as a magnesium transporter
CHR26_RS16655	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CHR26_RS16765	COG0582	viral genome integration into host DNA
CHR26_RS16770	COG1113	amino acid transport
CHR26_RS16780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR26_RS16790	COG1802	Transcriptional regulator
CHR26_RS16795	COG3706	GGDEF domain
CHR26_RS16800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR26_RS16810	COG0022	dehydrogenase e1 component
CHR26_RS16815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR26_RS16820	COG1522	sequence-specific DNA binding
CHR26_RS16835	COG0477	Major facilitator Superfamily
CHR26_RS16840	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CHR26_RS16860	COG0784	Response regulator, receiver
CHR26_RS16860	COG0835	chemotaxis
CHR26_RS16865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHR26_RS16870	COG1815	bacterial-type flagellum-dependent cell motility
CHR26_RS16880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CHR26_RS16895	COG4787	bacterial-type flagellum-dependent cell motility
CHR26_RS16905	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CHR26_RS16910	COG1706	bacterial-type flagellum-dependent cell motility
CHR26_RS16920	COG1256	bacterial-type flagellum assembly
CHR26_RS16920	COG4786	Flagellar basal body rod
CHR26_RS16930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR26_RS16945	COG1334	flagellar protein FlaG
CHR26_RS16950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CHR26_RS16970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CHR26_RS16990	COG0028	Belongs to the TPP enzyme family
CHR26_RS17020	COG0463	Glycosyl transferase, family 2
CHR26_RS17020	COG1216	Glycosyl transferase, family 2
CHR26_RS17025	COG1216	Glycosyl transferase, family 2
CHR26_RS17040	COG1677	Flagellar hook-basal body complex protein FliE
CHR26_RS17075	COG0745	RESPONSE REGULATOR receiver
CHR26_RS17115	COG1987	bacterial-type flagellum assembly
CHR26_RS17130	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHR26_RS17155	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CHR26_RS17160	COG0784	Response regulator, receiver
CHR26_RS17160	COG0643	Histidine kinase
CHR26_RS17160	COG2198	Histidine kinase
CHR26_RS17165	COG2201	protein-glutamate methylesterase activity
CHR26_RS17170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CHR26_RS17175	COG1360	Flagellar Motor Protein
CHR26_RS17185	COG1192	Involved in chromosome partitioning
CHR26_RS17195	COG0835	chemotaxis
CHR26_RS17215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHR26_RS17225	COG4133	protoheme IX ABC transporter activity
CHR26_RS17245	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CHR26_RS17250	COG1138	Cytochrome C-type biogenesis protein
CHR26_RS17285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR26_RS17320	COG1953	Uracil, thiamine, allantoin
CHR26_RS17325	COG1522	sequence-specific DNA binding
CHR26_RS17335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CHR26_RS17335	COG0116	Belongs to the methyltransferase superfamily
CHR26_RS17340	COG0668	transmembrane transport
CHR26_RS17355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR26_RS17370	COG0469	pyruvate kinase activity
CHR26_RS17380	COG2084	Dehydrogenase
CHR26_RS17385	COG3622	Belongs to the hyi family
CHR26_RS17390	COG3960	tartronate-semialdehyde synthase activity
CHR26_RS17410	COG2354	Protein conserved in bacteria
CHR26_RS17415	COG1368	sulfuric ester hydrolase activity
CHR26_RS17430	COG2233	PERMEase
CHR26_RS17440	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CHR26_RS17465	COG2252	PERMEase
CHR26_RS17480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHR26_RS17485	COG0402	S-adenosylhomocysteine deaminase activity
CHR26_RS17515	COG3115	cell septum assembly
CHR26_RS17525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHR26_RS17585	COG3645	SOS response
CHR26_RS17585	COG3646	Phage regulatory protein
CHR26_RS17625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHR26_RS17630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHR26_RS17635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHR26_RS17640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR26_RS17645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR26_RS17665	COG2217	Heavy metal translocating P-type atpase
CHR26_RS17675	COG0348	domain, Protein
CHR26_RS17680	COG2010	Cytochrome c
CHR26_RS17695	COG3278	Belongs to the heme-copper respiratory oxidase family
CHR26_RS17705	COG2010	Cytochrome c
CHR26_RS17720	COG3278	Belongs to the heme-copper respiratory oxidase family
CHR26_RS17730	COG3123	guanosine phosphorylase activity
CHR26_RS17795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR26_RS17815	COG2010	Cytochrome c
CHR26_RS17835	COG0642	Histidine kinase
CHR26_RS17870	COG0657	acetylesterase activity
CHR26_RS17890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR26_RS17910	COG1538	Outer membrane efflux protein
CHR26_RS17915	COG0577	efflux transmembrane transporter activity
CHR26_RS17915	COG1136	(ABC) transporter
CHR26_RS17920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS17940	COG0477	Major facilitator Superfamily
CHR26_RS17950	COG2944	sequence-specific DNA binding
CHR26_RS17985	COG3047	cAMP biosynthetic process
CHR26_RS17985	COG2885	chlorophyll binding
CHR26_RS17990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS18015	COG2009	succinate dehydrogenase
CHR26_RS18020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CHR26_RS18025	COG1053	succinate dehydrogenase
CHR26_RS18045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR26_RS18050	COG0045	succinate-CoA ligase (ADP-forming) activity
CHR26_RS18085	COG0326	Molecular chaperone. Has ATPase activity
CHR26_RS18095	COG1741	Belongs to the pirin family
CHR26_RS18110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHR26_RS18115	COG4999	Histidine kinase
CHR26_RS18115	COG3437	response regulator, receiver
CHR26_RS18115	COG2205	protein histidine kinase activity
CHR26_RS18115	COG3850	Histidine kinase
CHR26_RS18130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHR26_RS18165	COG0628	permease
CHR26_RS18175	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CHR26_RS18185	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CHR26_RS18190	COG2205	protein histidine kinase activity
CHR26_RS18195	COG0745	RESPONSE REGULATOR receiver
CHR26_RS18200	COG0583	DNA-binding transcription factor activity
CHR26_RS18210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR26_RS18220	COG4172	Belongs to the ABC transporter superfamily
CHR26_RS18225	COG4239	(ABC) transporter, permease
CHR26_RS18230	COG4174	ABC transporter (Permease)
CHR26_RS18235	COG4166	transmembrane transport
CHR26_RS18240	COG4166	transmembrane transport
CHR26_RS18250	COG1388	LysM domain
CHR26_RS18250	COG0741	lytic transglycosylase activity
CHR26_RS18255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR26_RS18265	COG0328	RNA-DNA hybrid ribonuclease activity
CHR26_RS18285	COG0431	NADPH-dependent FMN reductase
CHR26_RS18320	COG1007	ATP synthesis coupled electron transport
CHR26_RS18335	COG0713	ATP synthesis coupled electron transport
CHR26_RS18345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR26_RS18350	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHR26_RS18355	COG1034	ATP synthesis coupled electron transport
CHR26_RS18370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR26_RS18370	COG0649	NAD binding
CHR26_RS18375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR26_RS18380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR26_RS18410	COG0659	secondary active sulfate transmembrane transporter activity
CHR26_RS18415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHR26_RS18430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR26_RS18435	COG0583	DNA-binding transcription factor activity
CHR26_RS18440	COG1113	amino acid transport
CHR26_RS18445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CHR26_RS18445	COG2050	protein possibly involved in aromatic compounds catabolism
CHR26_RS18450	COG0625	glutathione transferase activity
CHR26_RS18455	COG0306	phosphate transporter
CHR26_RS18480	COG0322	excinuclease ABC activity
CHR26_RS18495	COG0582	viral genome integration into host DNA
CHR26_RS18530	COG0583	DNA-binding transcription factor activity
CHR26_RS18560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHR26_RS18565	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS18570	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS18580	COG0366	Alpha amylase catalytic
CHR26_RS18585	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHR26_RS18615	COG1640	4-alpha-glucanotransferase
CHR26_RS18620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHR26_RS18625	COG0297	glycogen (starch) synthase activity
CHR26_RS18635	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CHR26_RS18640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHR26_RS18645	COG3387	PFAM Glycoside hydrolase 15-related
CHR26_RS18655	COG1309	transcriptional regulator
CHR26_RS18670	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHR26_RS18680	COG1953	Uracil, thiamine, allantoin
CHR26_RS18695	COG1234	tRNA 3'-trailer cleavage
CHR26_RS18705	COG3040	lipid binding
CHR26_RS18710	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHR26_RS18715	COG1024	Enoyl-CoA hydratase
CHR26_RS18720	COG2816	NAD+ diphosphatase activity
CHR26_RS18735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS18745	COG2153	protein acetylation
CHR26_RS18750	COG2850	peptidyl-arginine hydroxylation
CHR26_RS18760	COG2915	High frequency lysogenization protein hflD homolog
CHR26_RS18765	COG0482	sulfurtransferase activity
CHR26_RS18790	COG1278	Cold shock
CHR26_RS18795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHR26_RS18800	COG0542	response to heat
CHR26_RS18805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHR26_RS18810	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CHR26_RS18815	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHR26_RS18820	COG1674	ftsk spoiiie
CHR26_RS18825	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CHR26_RS18830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHR26_RS18835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHR26_RS18840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHR26_RS18845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHR26_RS18845	COG1648	precorrin-2 dehydrogenase activity
CHR26_RS18850	COG0435	Glutathione S-transferase
CHR26_RS18855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHR26_RS18860	COG2920	part of a sulfur-relay system
CHR26_RS18880	COG2233	PERMEase
CHR26_RS18915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CHR26_RS18925	COG0840	transmembrane signaling receptor activity
CHR26_RS18930	COG0583	DNA-binding transcription factor activity
CHR26_RS18955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR26_RS18965	COG4948	Mandelate Racemase Muconate Lactonizing
CHR26_RS18970	COG0747	negative chemotaxis
CHR26_RS18975	COG0601	transmembrane transport
CHR26_RS18980	COG0747	negative chemotaxis
CHR26_RS18985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR26_RS18990	COG0444	Belongs to the ABC transporter superfamily
CHR26_RS18995	COG4608	Belongs to the ABC transporter superfamily
CHR26_RS19020	COG1309	transcriptional regulator
CHR26_RS19025	COG2010	Cytochrome c
CHR26_RS19025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHR26_RS19030	COG2080	2 iron, 2 sulfur cluster binding
CHR26_RS19035	COG1846	Transcriptional regulator
CHR26_RS19040	COG2309	aminopeptidase activity
CHR26_RS19045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR26_RS19050	COG0596	Alpha beta hydrolase
CHR26_RS19055	COG3473	Maleate cis-trans isomerase
CHR26_RS19060	COG1335	isochorismatase
CHR26_RS19065	COG2271	Major facilitator Superfamily
CHR26_RS19100	COG2199	diguanylate cyclase activity
CHR26_RS19105	COG0490	domain, Protein
CHR26_RS19105	COG0471	metal ion transport
CHR26_RS19135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR26_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS19160	COG0616	signal peptide processing
CHR26_RS19195	COG2135	peptidase activity
CHR26_RS19205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR26_RS19220	COG1064	alcohol dehydrogenase
CHR26_RS19230	COG2259	Doxx family
CHR26_RS19245	COG0784	Response regulator, receiver
CHR26_RS19245	COG4191	Histidine kinase
CHR26_RS19250	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CHR26_RS19260	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CHR26_RS19270	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CHR26_RS19300	COG2863	cytochrome
CHR26_RS19305	COG3258	Cytochrome c
CHR26_RS19330	COG3634	alkyl hydroperoxide reductase activity
CHR26_RS19340	COG3132	Protein of unknown function, DUF480
CHR26_RS19345	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHR26_RS19350	COG0583	DNA-binding transcription factor activity
CHR26_RS19360	COG1253	flavin adenine dinucleotide binding
CHR26_RS19370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS19415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR26_RS19420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR26_RS19425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CHR26_RS19430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHR26_RS19440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR26_RS19455	COG4772	TonB-dependent receptor
CHR26_RS19460	COG0252	asparaginase activity
CHR26_RS19470	COG1129	ABC transporter
CHR26_RS19475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR26_RS19480	COG1609	Transcriptional regulator
CHR26_RS19485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR26_RS19490	COG1869	D-ribose catabolic process
CHR26_RS19510	COG1278	Cold shock
CHR26_RS19520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHR26_RS19525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHR26_RS19530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHR26_RS19535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHR26_RS19540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHR26_RS19545	COG0072	phenylalanine-tRNA ligase activity
CHR26_RS19550	COG0776	regulation of translation
CHR26_RS19595	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR26_RS19605	COG0302	gtp cyclohydrolase
CHR26_RS19615	COG2828	Protein conserved in bacteria
CHR26_RS19620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHR26_RS19625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CHR26_RS19630	COG0583	DNA-binding transcription factor activity
CHR26_RS19635	COG3384	dioxygenase
CHR26_RS19650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS19655	COG0697	spore germination
CHR26_RS19660	COG2066	Belongs to the glutaminase family
CHR26_RS19685	COG0667	Aldo Keto reductase
CHR26_RS19705	COG2873	o-acetylhomoserine
CHR26_RS19725	COG1231	oxidoreductase activity
CHR26_RS19730	COG4771	TonB-dependent receptor
CHR26_RS19740	COG1024	Enoyl-CoA hydratase
CHR26_RS19745	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS19750	COG1022	Amp-dependent synthetase and ligase
CHR26_RS19755	COG0183	Belongs to the thiolase family
CHR26_RS19760	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS19765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CHR26_RS19780	COG2814	Major facilitator Superfamily
CHR26_RS19800	COG0583	DNA-binding transcription factor activity
CHR26_RS19805	COG2814	Major facilitator Superfamily
CHR26_RS19810	COG0625	glutathione transferase activity
CHR26_RS19830	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS19835	COG5642	Protein of unknown function (DUF2384)
CHR26_RS19840	COG5654	RES domain protein
CHR26_RS19845	COG1104	cysteine desulfurase activity
CHR26_RS19870	COG0861	Integral membrane protein TerC family
CHR26_RS19875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR26_RS19880	COG3842	ATPase activity
CHR26_RS19885	COG1177	transmembrane transport
CHR26_RS19890	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR26_RS19900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR26_RS19915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR26_RS19915	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR26_RS19925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS19930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHR26_RS19975	COG1121	(ABC) transporter
CHR26_RS20015	COG1686	Belongs to the peptidase S11 family
CHR26_RS20030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CHR26_RS20085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR26_RS20120	COG0784	Response regulator, receiver
CHR26_RS20120	COG2205	protein histidine kinase activity
CHR26_RS20120	COG2198	Histidine kinase
CHR26_RS20125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHR26_RS20135	COG3437	response regulator, receiver
CHR26_RS20135	COG2205	protein histidine kinase activity
CHR26_RS20135	COG4999	Histidine kinase
CHR26_RS20135	COG3850	Histidine kinase
CHR26_RS20140	COG2198	Histidine kinase
CHR26_RS20140	COG2205	protein histidine kinase activity
CHR26_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS20140	COG0784	Response regulator, receiver
CHR26_RS20150	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR26_RS20155	COG0183	Belongs to the thiolase family
CHR26_RS20165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR26_RS20170	COG2807	transmembrane transport
CHR26_RS20190	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CHR26_RS20195	COG0247	lactate metabolic process
CHR26_RS20200	COG0277	FAD linked oxidase domain protein
CHR26_RS20205	COG0277	FAD linked oxidase domain protein
CHR26_RS20210	COG2186	Transcriptional regulator
CHR26_RS20255	COG1309	transcriptional regulator
CHR26_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS20265	COG4221	oxidoreductase activity
CHR26_RS20280	COG0436	Aminotransferase
CHR26_RS20285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR26_RS20295	COG0028	Belongs to the TPP enzyme family
CHR26_RS20300	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS20305	COG2186	Transcriptional regulator
CHR26_RS20315	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR26_RS20340	COG0768	penicillin binding
CHR26_RS20375	COG4181	ATPase activity
CHR26_RS20380	COG0577	efflux transmembrane transporter activity
CHR26_RS20390	COG1024	Enoyl-CoA hydratase
CHR26_RS20415	COG0833	amino acid
CHR26_RS20420	COG1024	Enoyl-CoA hydratase
CHR26_RS20425	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS20430	COG0045	succinate-CoA ligase (ADP-forming) activity
CHR26_RS20440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHR26_RS20455	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHR26_RS20460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHR26_RS20480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR26_RS20500	COG0583	DNA-binding transcription factor activity
CHR26_RS20505	COG1522	sequence-specific DNA binding
CHR26_RS20515	COG1113	amino acid transport
CHR26_RS20525	COG4948	Mandelate Racemase Muconate Lactonizing
CHR26_RS20530	COG4829	muconolactone delta-isomerase
CHR26_RS20535	COG3485	protocatechuate 3,4-dioxygenase
CHR26_RS20545	COG5001	Diguanylate cyclase
CHR26_RS20555	COG0656	L-ascorbic acid biosynthetic process
CHR26_RS20565	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CHR26_RS20575	COG0477	Major facilitator Superfamily
CHR26_RS20585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR26_RS20590	COG3300	MHYT domain
CHR26_RS20590	COG5001	Diguanylate cyclase
CHR26_RS20595	COG1611	Belongs to the LOG family
CHR26_RS20600	COG2855	membrane
CHR26_RS20620	COG3920	Histidine kinase
CHR26_RS20635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHR26_RS20640	COG2218	PFAM glutamate synthase alpha subunit domain protein
CHR26_RS20645	COG0069	glutamate synthase activity
CHR26_RS20665	COG0784	Response regulator, receiver
CHR26_RS20665	COG4191	Histidine kinase
CHR26_RS20670	COG2816	NAD+ diphosphatase activity
CHR26_RS20675	COG2186	Transcriptional regulator
CHR26_RS20680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR26_RS20690	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS20695	COG2267	carboxylic ester hydrolase activity
CHR26_RS20705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS20710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR26_RS20715	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR26_RS20740	COG2207	Transcriptional regulator
CHR26_RS20755	COG1116	anion transmembrane transporter activity
CHR26_RS20760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS20765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS20775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHR26_RS20790	COG4991	sh3 domain protein
CHR26_RS20805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS20845	COG1944	ATP diphosphatase activity
CHR26_RS20885	COG4335	DNA alkylation repair
CHR26_RS20900	COG2391	methyltransferase activity
CHR26_RS20915	COG2186	Transcriptional regulator
CHR26_RS20920	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS20925	COG2721	sulfolactate sulfo-lyase activity
CHR26_RS20930	COG2271	Major facilitator Superfamily
CHR26_RS20935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR26_RS20940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR26_RS20945	COG1126	abc transporter atp-binding protein
CHR26_RS20950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS20960	COG4215	(ABC) transporter
CHR26_RS20985	COG0814	amino acid
CHR26_RS21035	COG1595	DNA-templated transcription, initiation
CHR26_RS21040	COG3712	iron ion homeostasis
CHR26_RS21045	COG4774	siderophore transport
CHR26_RS21060	COG2271	Major facilitator Superfamily
CHR26_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS21080	COG2072	flavoprotein involved in K transport
CHR26_RS21105	COG0583	DNA-binding transcription factor activity
CHR26_RS21110	COG2814	Major facilitator Superfamily
CHR26_RS21115	COG1280	lysine exporter protein (LysE YggA)
CHR26_RS21140	COG0583	DNA-binding transcription factor activity
CHR26_RS21145	COG4176	ABC-type proline glycine betaine transport system permease component
CHR26_RS21155	COG0840	transmembrane signaling receptor activity
CHR26_RS21165	COG2056	Na+-H+ antiporter family
CHR26_RS21175	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS21180	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS21190	COG4566	intracellular signal transduction
CHR26_RS21195	COG1846	Transcriptional regulator
CHR26_RS21200	COG1566	PFAM secretion protein HlyD family protein
CHR26_RS21205	COG2814	Major facilitator Superfamily
CHR26_RS21210	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS21215	COG4191	Histidine kinase
CHR26_RS21215	COG0784	Response regulator, receiver
CHR26_RS21225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS21230	COG0348	domain, Protein
CHR26_RS21240	COG1285	pathogenesis
CHR26_RS21250	COG0789	Transcriptional regulator
CHR26_RS21255	COG2207	Transcriptional regulator
CHR26_RS21270	COG0405	Gamma-glutamyltransferase
CHR26_RS21275	COG0583	DNA-binding transcription factor activity
CHR26_RS21285	COG2423	ornithine cyclodeaminase activity
CHR26_RS21290	COG1522	sequence-specific DNA binding
CHR26_RS21295	COG1113	amino acid transport
CHR26_RS21305	COG3257	ureidoglycine aminohydrolase activity
CHR26_RS21315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS21325	COG0697	spore germination
CHR26_RS21330	COG1309	transcriptional regulator
CHR26_RS21365	COG0583	DNA-binding transcription factor activity
CHR26_RS21375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR26_RS21380	COG0488	(ABC) transporter
CHR26_RS21420	COG2204	response regulator
CHR26_RS21425	COG0826	peptidase U32
CHR26_RS21435	COG2384	SAM-dependent methyltransferase
CHR26_RS21450	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS21545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR26_RS21570	COG4796	Type ii and iii secretion system protein
CHR26_RS21580	COG2165	general secretion pathway protein
CHR26_RS21615	COG3284	Transcriptional regulator
CHR26_RS21620	COG1132	(ABC) transporter
CHR26_RS21675	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS21680	COG0746	molybdenum cofactor guanylyltransferase activity
CHR26_RS21690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS21695	COG0745	RESPONSE REGULATOR receiver
CHR26_RS21700	COG2205	protein histidine kinase activity
CHR26_RS21705	COG3706	GGDEF domain
CHR26_RS21720	COG1215	transferase activity, transferring glycosyl groups
CHR26_RS21730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHR26_RS21740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR26_RS21755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR26_RS21780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR26_RS21785	COG4574	serine-type endopeptidase inhibitor activity
CHR26_RS21790	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS21795	COG4239	(ABC) transporter, permease
CHR26_RS21800	COG4174	ABC transporter (Permease)
CHR26_RS21810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR26_RS21815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHR26_RS21820	COG1881	PFAM PEBP family protein
CHR26_RS21855	COG1473	amidohydrolase
CHR26_RS21865	COG0154	amidase activity
CHR26_RS21870	COG1414	Transcriptional regulator
CHR26_RS21880	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS21885	COG1053	succinate dehydrogenase
CHR26_RS21910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHR26_RS21925	COG0587	DNA-directed DNA polymerase activity
CHR26_RS21935	COG0656	L-ascorbic acid biosynthetic process
CHR26_RS21945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CHR26_RS21955	COG2031	fatty acid transporter
CHR26_RS21960	COG1396	sequence-specific DNA binding
CHR26_RS21985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHR26_RS22030	COG1215	transferase activity, transferring glycosyl groups
CHR26_RS22035	COG2990	Protein conserved in bacteria
CHR26_RS22040	COG0438	transferase activity, transferring glycosyl groups
CHR26_RS22055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHR26_RS22060	COG0583	DNA-binding transcription factor activity
CHR26_RS22065	COG1760	l-serine dehydratase
CHR26_RS22075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS22085	COG0174	glutamine synthetase
CHR26_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS22105	COG0583	DNA-binding transcription factor activity
CHR26_RS22175	COG2814	Major facilitator Superfamily
CHR26_RS22180	COG3485	protocatechuate 3,4-dioxygenase
CHR26_RS22190	COG3135	benzoate transporter
CHR26_RS22215	COG1278	Cold shock
CHR26_RS22220	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS22225	COG0667	Aldo Keto reductase
CHR26_RS22230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR26_RS22235	COG2271	Major facilitator Superfamily
CHR26_RS22240	COG3835	regulator
CHR26_RS22245	COG1929	Belongs to the glycerate kinase type-1 family
CHR26_RS22250	COG0583	DNA-binding transcription factor activity
CHR26_RS22255	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS22270	COG1999	signal sequence binding
CHR26_RS22285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CHR26_RS22290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR26_RS22300	COG0402	S-adenosylhomocysteine deaminase activity
CHR26_RS22305	COG2423	ornithine cyclodeaminase activity
CHR26_RS22310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHR26_RS22370	COG2837	iron assimilation
CHR26_RS22375	COG0667	Aldo Keto reductase
CHR26_RS22400	COG2890	protein-(glutamine-N5) methyltransferase activity
CHR26_RS22405	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CHR26_RS22425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CHR26_RS22450	COG0392	lysyltransferase activity
CHR26_RS22460	COG3568	Endonuclease Exonuclease Phosphatase
CHR26_RS22475	COG0494	nUDIX hydrolase
CHR26_RS22485	COG1063	alcohol dehydrogenase
CHR26_RS22500	COG2030	dehydratase
CHR26_RS22500	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS22515	COG3162	membrane
CHR26_RS22520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR26_RS22525	COG2151	metal-sulfur cluster biosynthetic enzyme
CHR26_RS22530	COG3396	Phenylacetate-CoA oxygenase
CHR26_RS22535	COG3460	Phenylacetate-CoA oxygenase
CHR26_RS22540	COG3396	Phenylacetate-CoA oxygenase
CHR26_RS22550	COG0183	Belongs to the thiolase family
CHR26_RS22555	COG2050	protein possibly involved in aromatic compounds catabolism
CHR26_RS22560	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR26_RS22565	COG1024	Enoyl-CoA hydratase
CHR26_RS22570	COG1024	Enoyl-CoA hydratase
CHR26_RS22580	COG3327	negative regulation of DNA-templated transcription, initiation
CHR26_RS22585	COG0668	transmembrane transport
CHR26_RS22625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CHR26_RS22630	COG1846	Transcriptional regulator
CHR26_RS22645	COG0346	lactoylglutathione lyase activity
CHR26_RS22675	COG0477	Major facilitator Superfamily
CHR26_RS22695	COG2271	Major facilitator Superfamily
CHR26_RS22700	COG2721	sulfolactate sulfo-lyase activity
CHR26_RS22725	COG0784	Response regulator, receiver
CHR26_RS22725	COG4191	Histidine kinase
CHR26_RS22740	COG0300	oxidoreductase activity
CHR26_RS22785	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS22790	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS22810	COG2814	Major facilitator Superfamily
CHR26_RS22820	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS22820	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR26_RS22835	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS22840	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS22845	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS22860	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS22870	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS22875	COG1024	Enoyl-CoA hydratase
CHR26_RS22910	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS22915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR26_RS22930	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CHR26_RS22935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR26_RS22940	COG2814	Major facilitator Superfamily
CHR26_RS22955	COG1126	abc transporter atp-binding protein
CHR26_RS22960	COG0765	amino acid transport
CHR26_RS22965	COG0765	amino acid transport
CHR26_RS22980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR26_RS22995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHR26_RS23040	COG0765	amino acid transport
CHR26_RS23045	COG1126	abc transporter atp-binding protein
CHR26_RS23050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS23055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS23060	COG1522	sequence-specific DNA binding
CHR26_RS23065	COG2814	Major facilitator Superfamily
CHR26_RS23075	COG0667	Aldo Keto reductase
CHR26_RS23080	COG2205	protein histidine kinase activity
CHR26_RS23085	COG0745	RESPONSE REGULATOR receiver
CHR26_RS23090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHR26_RS23100	COG2356	endonuclease I
CHR26_RS23110	COG2271	Major facilitator Superfamily
CHR26_RS23115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR26_RS23125	COG1609	Transcriptional regulator
CHR26_RS23195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHR26_RS23200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR26_RS23270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS23275	COG0667	Aldo Keto reductase
CHR26_RS23280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS23285	COG4771	TonB-dependent receptor
CHR26_RS23290	COG1609	Transcriptional regulator
CHR26_RS23295	COG0583	DNA-binding transcription factor activity
CHR26_RS23300	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS23310	COG0235	Class ii aldolase
CHR26_RS23315	COG0747	negative chemotaxis
CHR26_RS23320	COG0601	transmembrane transport
CHR26_RS23325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR26_RS23335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS23340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS23370	COG3813	Protein conserved in bacteria
CHR26_RS23375	COG2197	response regulator
CHR26_RS23380	COG2205	protein histidine kinase activity
CHR26_RS23380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR26_RS23390	COG1609	Transcriptional regulator
CHR26_RS23395	COG3265	gluconokinase activity
CHR26_RS23410	COG2204	response regulator
CHR26_RS23415	COG2205	protein histidine kinase activity
CHR26_RS23425	COG5002	protein histidine kinase activity
CHR26_RS23430	COG1196	nuclear chromosome segregation
CHR26_RS23430	COG0741	lytic transglycosylase activity
CHR26_RS23430	COG0739	heme binding
CHR26_RS23440	COG1459	type II secretion system
CHR26_RS23445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS23465	COG1595	DNA-templated transcription, initiation
CHR26_RS23470	COG3712	iron ion homeostasis
CHR26_RS23480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR26_RS23505	COG4191	Histidine kinase
CHR26_RS23505	COG0784	Response regulator, receiver
CHR26_RS23525	COG2200	EAL domain
CHR26_RS23535	COG1253	flavin adenine dinucleotide binding
CHR26_RS23645	COG0488	(ABC) transporter
CHR26_RS23660	COG0625	glutathione transferase activity
CHR26_RS23680	COG0019	diaminopimelate decarboxylase activity
CHR26_RS23705	COG0463	Glycosyl transferase, family 2
CHR26_RS23715	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CHR26_RS23720	COG0579	oxidoreductase
CHR26_RS23765	COG1984	allophanate hydrolase subunit 2
CHR26_RS23775	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR26_RS23790	COG0307	riboflavin synthase, alpha
CHR26_RS23805	COG0113	porphobilinogen synthase activity
CHR26_RS23815	COG1113	amino acid transport
CHR26_RS23820	COG0579	oxidoreductase
CHR26_RS23830	COG1802	Transcriptional regulator
CHR26_RS23835	COG0745	RESPONSE REGULATOR receiver
CHR26_RS23840	COG3850	Histidine kinase
CHR26_RS23840	COG5002	protein histidine kinase activity
CHR26_RS23855	COG0215	cysteine-tRNA ligase activity
CHR26_RS23860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHR26_RS23870	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR26_RS23875	COG2366	antibiotic biosynthetic process
CHR26_RS23915	COG0729	surface antigen
CHR26_RS23925	COG0708	Exodeoxyribonuclease III
CHR26_RS23935	COG1595	DNA-templated transcription, initiation
CHR26_RS23945	COG3038	cytochrome b561
CHR26_RS23955	COG1917	Cupin 2, conserved barrel domain protein
CHR26_RS23955	COG1396	sequence-specific DNA binding
CHR26_RS23970	COG4221	oxidoreductase activity
CHR26_RS24010	COG0393	Putative heavy-metal-binding
CHR26_RS24020	COG0235	Class ii aldolase
CHR26_RS24030	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS24030	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR26_RS24040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHR26_RS24045	COG0583	DNA-binding transcription factor activity
CHR26_RS24060	COG1968	undecaprenyl-diphosphatase activity
CHR26_RS24065	COG0840	transmembrane signaling receptor activity
CHR26_RS24120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHR26_RS24125	COG0830	nickel cation binding
CHR26_RS24135	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CHR26_RS24140	COG0804	urea catabolic process
CHR26_RS24145	COG0832	Belongs to the urease beta subunit family
CHR26_RS24150	COG0831	urea catabolic process
CHR26_RS24155	COG0829	nickel cation binding
CHR26_RS24160	COG4974	Belongs to the 'phage' integrase family
CHR26_RS24165	COG1199	ATP-dependent helicase activity
CHR26_RS24165	COG1199	ATP-dependent helicase activity
CHR26_RS24190	COG2721	sulfolactate sulfo-lyase activity
CHR26_RS24195	COG0583	DNA-binding transcription factor activity
CHR26_RS24205	COG4948	Mandelate Racemase Muconate Lactonizing
CHR26_RS24215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS24230	COG0604	alcohol dehydrogenase
CHR26_RS24230	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS24230	COG3321	synthase
CHR26_RS24265	COG1473	amidohydrolase
CHR26_RS24275	COG2807	transmembrane transport
CHR26_RS24290	COG3842	ATPase activity
CHR26_RS24295	COG1177	transmembrane transport
CHR26_RS24300	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR26_RS24305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHR26_RS24325	COG2508	Transcriptional regulator
CHR26_RS24385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS24420	COG1192	Involved in chromosome partitioning
CHR26_RS24465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHR26_RS24525	COG1595	DNA-templated transcription, initiation
CHR26_RS24530	COG3712	iron ion homeostasis
CHR26_RS24535	COG4774	siderophore transport
CHR26_RS24545	COG0668	transmembrane transport
CHR26_RS24550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR26_RS24555	COG2358	TRAP transporter, solute receptor (TAXI family
CHR26_RS24570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS24575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHR26_RS24710	COG1129	ABC transporter
CHR26_RS24740	COG1309	transcriptional regulator
CHR26_RS24745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHR26_RS24750	COG0386	Belongs to the glutathione peroxidase family
CHR26_RS24770	COG1024	Enoyl-CoA hydratase
CHR26_RS24775	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS24780	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS24790	COG2124	cytochrome p450
CHR26_RS24800	COG0183	Belongs to the thiolase family
CHR26_RS24805	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR26_RS24810	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR26_RS24840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CHR26_RS24850	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR26_RS24855	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS24880	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR26_RS24900	COG2223	nitrite transmembrane transporter activity
CHR26_RS24905	COG0633	Ferredoxin
CHR26_RS24915	COG4221	oxidoreductase activity
CHR26_RS24940	COG2124	cytochrome p450
CHR26_RS24945	COG1309	transcriptional regulator
CHR26_RS24955	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS24960	COG1024	Enoyl-CoA hydratase
CHR26_RS24975	COG4447	cellulose binding
CHR26_RS24990	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS25010	COG0583	DNA-binding transcription factor activity
CHR26_RS25015	COG1063	alcohol dehydrogenase
CHR26_RS25045	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS25080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR26_RS25085	COG0531	amino acid
CHR26_RS25135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR26_RS25140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR26_RS25165	COG4191	Histidine kinase
CHR26_RS25165	COG0784	Response regulator, receiver
CHR26_RS25180	COG3685	Protein conserved in bacteria
CHR26_RS25190	COG3546	catalase activity
CHR26_RS25195	COG3685	Protein conserved in bacteria
CHR26_RS25205	COG1063	alcohol dehydrogenase
CHR26_RS25210	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS25245	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS25250	COG1058	Belongs to the CinA family
CHR26_RS25250	COG1546	Belongs to the CinA family
CHR26_RS25260	COG2323	membrane
CHR26_RS25265	COG3387	PFAM Glycoside hydrolase 15-related
CHR26_RS25285	COG3300	MHYT domain
CHR26_RS25285	COG5001	Diguanylate cyclase
CHR26_RS25305	COG0028	Belongs to the TPP enzyme family
CHR26_RS25310	COG2080	2 iron, 2 sulfur cluster binding
CHR26_RS25315	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CHR26_RS25320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHR26_RS25340	COG1063	alcohol dehydrogenase
CHR26_RS25340	COG1063	alcohol dehydrogenase
CHR26_RS25365	COG2205	protein histidine kinase activity
CHR26_RS25370	COG0708	Exodeoxyribonuclease III
CHR26_RS25380	COG0693	protein deglycase activity
CHR26_RS25385	COG1595	DNA-templated transcription, initiation
CHR26_RS25390	COG3712	iron ion homeostasis
CHR26_RS25410	COG3568	Endonuclease Exonuclease Phosphatase
CHR26_RS25415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR26_RS25420	COG0392	lysyltransferase activity
CHR26_RS25450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CHR26_RS25470	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CHR26_RS25495	COG0668	transmembrane transport
CHR26_RS25505	COG1285	pathogenesis
CHR26_RS25570	COG1501	Belongs to the glycosyl hydrolase 31 family
CHR26_RS25575	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR26_RS25585	COG0730	response to heat
CHR26_RS25590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR26_RS25595	COG2271	Major facilitator Superfamily
CHR26_RS25625	COG3158	transport of potassium into the cell
CHR26_RS25630	COG0789	Transcriptional regulator
CHR26_RS25635	COG1366	Belongs to the anti-sigma-factor antagonist family
CHR26_RS25645	COG4221	oxidoreductase activity
CHR26_RS25660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHR26_RS25675	COG3046	protein related to deoxyribodipyrimidine photolyase
CHR26_RS25725	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS25735	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS25760	COG1063	alcohol dehydrogenase
CHR26_RS25765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR26_RS25770	COG4944	Protein of unknown function (DUF1109)
CHR26_RS25775	COG1595	DNA-templated transcription, initiation
CHR26_RS25785	COG3220	belongs to the UPF0276 family
CHR26_RS25815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHR26_RS25825	COG0640	Transcriptional regulator
CHR26_RS25835	COG0431	NADPH-dependent FMN reductase
CHR26_RS25845	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CHR26_RS25865	COG2080	2 iron, 2 sulfur cluster binding
CHR26_RS25870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CHR26_RS25875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHR26_RS25885	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS25900	COG4191	Histidine kinase
CHR26_RS25900	COG0784	Response regulator, receiver
CHR26_RS25915	COG2172	sigma factor antagonist activity
CHR26_RS25920	COG1366	Belongs to the anti-sigma-factor antagonist family
CHR26_RS25925	COG1366	Belongs to the anti-sigma-factor antagonist family
CHR26_RS25930	COG0693	protein deglycase activity
CHR26_RS25940	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS25950	COG0028	Belongs to the TPP enzyme family
CHR26_RS25955	COG0708	Exodeoxyribonuclease III
CHR26_RS25965	COG1473	amidohydrolase
CHR26_RS25980	COG0583	DNA-binding transcription factor activity
CHR26_RS25985	COG0678	peroxiredoxin activity
CHR26_RS25990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHR26_RS25995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHR26_RS26015	COG1113	amino acid transport
CHR26_RS26035	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS26040	COG0010	Belongs to the arginase family
CHR26_RS26055	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS26065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR26_RS26080	COG0251	oxidation-reduction process
CHR26_RS26085	COG2308	Evidence 4 Homologs of previously reported genes of
CHR26_RS26095	COG1305	Transglutaminase-like
CHR26_RS26110	COG2610	gluconate transmembrane transporter activity
CHR26_RS26115	COG3048	D-serine ammonia-lyase activity
CHR26_RS26120	COG0583	DNA-binding transcription factor activity
CHR26_RS26125	COG0784	Response regulator, receiver
CHR26_RS26125	COG2205	protein histidine kinase activity
CHR26_RS26125	COG5002	protein histidine kinase activity
CHR26_RS26200	COG1131	(ABC) transporter
CHR26_RS26220	COG2205	protein histidine kinase activity
CHR26_RS26220	COG0784	Response regulator, receiver
CHR26_RS26245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR26_RS26250	COG0581	inorganic phosphate transmembrane transporter activity
CHR26_RS26260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR26_RS26290	COG2271	Major facilitator Superfamily
CHR26_RS26330	COG1309	transcriptional regulator
CHR26_RS26380	COG3459	Glycosyltransferase 36 associated
CHR26_RS26400	COG1595	DNA-templated transcription, initiation
CHR26_RS26420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR26_RS26425	COG1132	(ABC) transporter
CHR26_RS26430	COG1414	Transcriptional regulator
CHR26_RS26435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR26_RS26440	COG1053	succinate dehydrogenase
CHR26_RS26450	COG1053	succinate dehydrogenase
CHR26_RS26510	COG0673	inositol 2-dehydrogenase activity
CHR26_RS26520	COG1053	succinate dehydrogenase
CHR26_RS26525	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS26545	COG0531	amino acid
CHR26_RS26550	COG1012	belongs to the aldehyde dehydrogenase family
CHR26_RS26555	COG0583	DNA-binding transcription factor activity
CHR26_RS26565	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CHR26_RS26585	COG0583	DNA-binding transcription factor activity
CHR26_RS26600	COG2233	PERMEase
CHR26_RS26605	COG4221	oxidoreductase activity
CHR26_RS26620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHR26_RS26625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR26_RS26630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHR26_RS26675	COG2194	sulfuric ester hydrolase activity
CHR26_RS26680	COG1309	transcriptional regulator
CHR26_RS26695	COG3008	intermembrane lipid transfer
CHR26_RS26700	COG2995	paraquat-inducible protein a
CHR26_RS26720	COG0346	lactoylglutathione lyase activity
CHR26_RS26730	COG0477	Major facilitator Superfamily
CHR26_RS26750	COG0596	Alpha beta hydrolase
CHR26_RS26765	COG0210	DNA helicase
CHR26_RS26780	COG1595	DNA-templated transcription, initiation
CHR26_RS26785	COG3712	iron ion homeostasis
CHR26_RS26800	COG4774	siderophore transport
CHR26_RS26810	COG1595	DNA-templated transcription, initiation
CHR26_RS26825	COG3829	transcription factor binding
CHR26_RS26840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS26855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS26865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR26_RS26875	COG0747	negative chemotaxis
CHR26_RS26880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS26900	COG1132	(ABC) transporter
CHR26_RS26905	COG1132	(ABC) transporter
CHR26_RS26910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR26_RS26925	COG4771	TonB-dependent receptor
CHR26_RS26930	COG4206	TonB-dependent receptor
CHR26_RS26935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS26940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR26_RS26945	COG1116	anion transmembrane transporter activity
CHR26_RS26955	COG1082	Xylose isomerase domain protein TIM barrel
CHR26_RS26955	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CHR26_RS26965	COG0076	glutamate decarboxylase activity
CHR26_RS26970	COG0583	DNA-binding transcription factor activity
CHR26_RS26975	COG0217	transcriptional regulatory protein
CHR26_RS26980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR26_RS26990	COG0583	DNA-binding transcription factor activity
CHR26_RS27000	COG4106	trans-aconitate 2-methyltransferase activity
CHR26_RS27015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS27030	COG0583	DNA-binding transcription factor activity
CHR26_RS27035	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS27050	COG0583	DNA-binding transcription factor activity
CHR26_RS27065	COG2814	Major facilitator Superfamily
CHR26_RS27075	COG1064	alcohol dehydrogenase
CHR26_RS27080	COG2207	Transcriptional regulator
CHR26_RS27095	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHR26_RS27125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR26_RS27145	COG4774	siderophore transport
CHR26_RS27160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR26_RS27165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CHR26_RS27200	COG1192	Involved in chromosome partitioning
CHR26_RS27210	COG4774	siderophore transport
CHR26_RS27215	COG0477	Major facilitator Superfamily
CHR26_RS27235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHR26_RS27240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR26_RS27270	COG2205	protein histidine kinase activity
CHR26_RS27285	COG0417	DNA replication proofreading
CHR26_RS27290	COG2814	Major facilitator Superfamily
CHR26_RS27295	COG0583	DNA-binding transcription factor activity
CHR26_RS27300	COG0583	DNA-binding transcription factor activity
CHR26_RS27355	COG1999	signal sequence binding
CHR26_RS27360	COG0316	Belongs to the HesB IscA family
CHR26_RS27360	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CHR26_RS27365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CHR26_RS27410	COG2223	nitrite transmembrane transporter activity
CHR26_RS27415	COG2207	Transcriptional regulator
CHR26_RS27420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS27425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS27430	COG2365	Tyrosine phosphatase family
CHR26_RS27440	COG2866	Carboxypeptidase
CHR26_RS27480	COG4251	negative regulation of phosphorylation
CHR26_RS27485	COG0745	RESPONSE REGULATOR receiver
CHR26_RS27505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHR26_RS27520	COG0517	IMP dehydrogenase activity
CHR26_RS27550	COG0720	synthase
CHR26_RS27565	COG2079	MmgE PrpD family protein
CHR26_RS27580	COG0372	Belongs to the citrate synthase family
CHR26_RS27590	COG1802	Transcriptional regulator
CHR26_RS27595	COG4067	protein conserved in archaea
CHR26_RS27595	COG0189	ligase activity
CHR26_RS27625	COG0589	response to stress
CHR26_RS27630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHR26_RS27650	COG1376	ErfK ybiS ycfS ynhG family protein
CHR26_RS27650	COG1388	LysM domain
CHR26_RS27665	COG4181	ATPase activity
CHR26_RS27670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CHR26_RS27675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR26_RS27685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CHR26_RS27725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR26_RS27735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHR26_RS27740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHR26_RS27745	COG0740	serine-type endopeptidase activity
CHR26_RS27750	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHR26_RS27780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHR26_RS27790	COG0840	transmembrane signaling receptor activity
CHR26_RS27800	COG2186	Transcriptional regulator
CHR26_RS27820	COG0583	DNA-binding transcription factor activity
CHR26_RS27825	COG0840	transmembrane signaling receptor activity
CHR26_RS27830	COG0251	oxidation-reduction process
CHR26_RS27835	COG0730	response to heat
CHR26_RS27865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHR26_RS27870	COG3246	L-lysine catabolic process to acetate
CHR26_RS27875	COG0318	PFAM AMP-dependent synthetase and ligase
CHR26_RS27885	COG4447	cellulose binding
CHR26_RS27910	COG2855	membrane
CHR26_RS27925	COG2175	clavaminate synthase activity
CHR26_RS27935	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS27960	COG2909	trisaccharide binding
CHR26_RS27965	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS27975	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR26_RS27975	COG1024	Enoyl-CoA hydratase
CHR26_RS27980	COG0183	Belongs to the thiolase family
CHR26_RS28030	COG5006	permease, DMT superfamily
CHR26_RS28065	COG1335	isochorismatase
CHR26_RS28080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHR26_RS28080	COG2111	Na H antiporter
CHR26_RS28085	COG1006	Multisubunit Na H antiporter MnhC subunit
CHR26_RS28090	COG0651	ATP synthesis coupled electron transport
CHR26_RS28100	COG2212	antiporter activity
CHR26_RS28105	COG1320	monovalent cation:proton antiporter activity
CHR26_RS28130	COG1024	Enoyl-CoA hydratase
CHR26_RS28135	COG1960	acyl-CoA dehydrogenase activity
CHR26_RS28140	COG0183	Belongs to the thiolase family
CHR26_RS28150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR26_RS28160	COG2207	Transcriptional regulator
CHR26_RS28165	COG0583	DNA-binding transcription factor activity
CHR26_RS28170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CHR26_RS28175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR26_RS28180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHR26_RS28185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR26_RS28195	COG0826	peptidase U32
CHR26_RS28215	COG1238	metal cluster binding
CHR26_RS28220	COG0596	Alpha beta hydrolase
CHR26_RS28225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHR26_RS28230	COG2133	pyrroloquinoline quinone binding
CHR26_RS28240	COG0010	Belongs to the arginase family
CHR26_RS28285	COG0589	response to stress
CHR26_RS28295	COG3383	formate dehydrogenase (NAD+) activity
CHR26_RS28360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR26_RS28365	COG0174	glutamine synthetase
CHR26_RS28375	COG0583	DNA-binding transcription factor activity
CHR26_RS28380	COG1028	Short-chain dehydrogenase reductase Sdr
CHR26_RS28420	COG1953	Uracil, thiamine, allantoin
CHR26_RS28435	COG5002	protein histidine kinase activity
CHR26_RS28480	COG0456	acetyltransferase
CHR26_RS28480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CHR26_RS28490	COG1595	DNA-templated transcription, initiation
CHR26_RS28495	COG3712	iron ion homeostasis
CHR26_RS28520	COG1605	Chorismate mutase
CHR26_RS28520	COG0077	Prephenate dehydratase
CHR26_RS28530	COG0583	DNA-binding transcription factor activity
CHR26_RS28540	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CHR26_RS28555	COG0402	S-adenosylhomocysteine deaminase activity
CHR26_RS28580	COG1595	DNA-templated transcription, initiation
CHR26_RS28615	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHR26_RS28730	COG0740	serine-type endopeptidase activity
CHR26_RS28735	COG4695	Portal protein
CHR26_RS28815	COG3311	Transcriptional regulator
CHR26_RS28820	COG0582	viral genome integration into host DNA
CHR26_RS28935	COG5532	Uncharacterized conserved protein (DUF2303)
CHR26_RS28975	COG0270	DNA (cytosine-5-)-methyltransferase activity
CHR26_RS29050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHR26_RS29055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHR26_RS29070	COG4566	intracellular signal transduction
CHR26_RS29080	COG2853	Lipoprotein
CHR26_RS29095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHR26_RS29095	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHR26_RS29115	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHR26_RS29120	COG1136	(ABC) transporter
CHR26_RS29125	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHR26_RS29135	COG0584	glycerophosphoryl diester phosphodiesterase
CHR26_RS29140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR26_RS29145	COG1477	protein flavinylation
CHR26_RS29155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHR26_RS29165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR26_RS29175	COG1376	ErfK ybiS ycfS ynhG family protein
CHR26_RS29185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHR26_RS29215	COG0183	Belongs to the thiolase family
CHR26_RS29220	COG1024	Enoyl-CoA hydratase
CHR26_RS29220	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR26_RS29230	COG0589	response to stress
CHR26_RS29235	COG0488	(ABC) transporter
CHR26_RS29240	COG0741	lytic transglycosylase activity
CHR26_RS29250	COG0784	Response regulator, receiver
CHR26_RS29250	COG0835	chemotaxis
CHR26_RS29260	COG3851	Histidine kinase
CHR26_RS29265	COG2197	response regulator
CHR26_RS29270	COG1597	lipid kinase activity
CHR26_RS29285	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHR26_RS29305	COG1132	(ABC) transporter
CHR26_RS29310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR26_RS29315	COG0425	Belongs to the sulfur carrier protein TusA family
CHR26_RS29330	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CHR26_RS29340	COG0840	transmembrane signaling receptor activity
CHR26_RS29365	COG0004	ammonium transporteR
CHR26_RS29390	COG2197	response regulator
CHR26_RS29400	COG3171	Protein conserved in bacteria
CHR26_RS29405	COG2027	D-alanyl-D-alanine carboxypeptidase
CHR26_RS29415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CHR26_RS29415	COG0116	Belongs to the methyltransferase superfamily
CHR26_RS29420	COG3130	regulation of translation
CHR26_RS29425	COG0167	dihydroorotate dehydrogenase activity
CHR26_RS29430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR26_RS29430	COG1116	anion transmembrane transporter activity
CHR26_RS29435	COG3707	response regulator
CHR26_RS29440	COG2223	nitrite transmembrane transporter activity
CHR26_RS29450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHR26_RS29465	COG0668	transmembrane transport
CHR26_RS29480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHR26_RS29495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CHR26_RS29510	COG0583	DNA-binding transcription factor activity
CHR26_RS29515	COG0019	diaminopimelate decarboxylase activity
CHR26_RS29525	COG1595	DNA-templated transcription, initiation
CHR26_RS29555	COG1538	Outer membrane efflux protein
CHR26_RS29570	COG2188	Transcriptional regulator
CHR26_RS29575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR26_RS29585	COG0789	Transcriptional regulator
CHR26_RS29590	COG3237	CsbD-like
CHR26_RS29600	COG2851	Citrate transporter
CHR26_RS29605	COG1301	dicarboxylic acid transport
CHR26_RS29610	COG2828	Protein conserved in bacteria
CHR26_RS29615	COG0583	DNA-binding transcription factor activity
CHR26_RS29635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR26_RS29640	COG3135	benzoate transporter
CHR26_RS29645	COG2814	Major facilitator Superfamily
CHR26_RS29655	COG0714	Associated with various cellular activities
CHR26_RS29685	COG0420	3'-5' exonuclease activity
CHR26_RS29705	COG2706	6-phosphogluconolactonase activity
CHR26_RS29725	COG0308	aminopeptidase N
CHR26_RS29735	COG3139	Protein of unknown function (DUF1315)
CHR26_RS29740	COG0705	Rhomboid family
CHR26_RS29745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR26_RS29750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHR26_RS29760	COG3038	cytochrome b561
CHR26_RS29770	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR26_RS29770	COG1902	pentaerythritol trinitrate reductase activity
CHR26_RS29825	COG1286	toxin biosynthetic process
CHR26_RS29835	COG0285	dihydrofolate synthase activity
CHR26_RS29840	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHR26_RS29845	COG0135	phosphoribosylanthranilate isomerase activity
CHR26_RS29870	COG0473	3-isopropylmalate dehydrogenase activity
CHR26_RS29875	COG2226	methyltransferase
CHR26_RS29880	COG0066	3-isopropylmalate dehydratase activity
CHR26_RS29885	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate