locus-tag	class	description
KF715C_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KF715C_RS00010	COG0592	DNA-directed DNA polymerase activity
KF715C_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KF715C_RS00020	COG0187	DNA topoisomerase II activity
KF715C_RS00060	COG0477	Major facilitator Superfamily
KF715C_RS00070	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KF715C_RS00075	COG0751	glycine-tRNA ligase activity
KF715C_RS00080	COG0752	glycyl-tRNA synthetase alpha subunit
KF715C_RS00085	COG2818	Glycosylase
KF715C_RS00100	COG0569	domain protein
KF715C_RS00105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KF715C_RS00110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KF715C_RS00115	COG0242	peptide deformylase activity
KF715C_RS00120	COG3344	reverse transcriptase
KF715C_RS00125	COG0758	DNA mediated transformation
KF715C_RS00130	COG0009	L-threonylcarbamoyladenylate synthase
KF715C_RS00150	COG0408	coproporphyrinogen oxidase activity
KF715C_RS00155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KF715C_RS00160	COG0659	secondary active sulfate transmembrane transporter activity
KF715C_RS00170	COG3119	arylsulfatase activity
KF715C_RS00190	COG0159	tryptophan synthase activity
KF715C_RS00195	COG0133	tryptophan synthase activity
KF715C_RS00210	COG3360	Dodecin
KF715C_RS00220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS00225	COG1764	response to oxidative stress
KF715C_RS00255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KF715C_RS00260	COG0339	signal peptide processing
KF715C_RS00265	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KF715C_RS00280	COG0659	secondary active sulfate transmembrane transporter activity
KF715C_RS00290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KF715C_RS00295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KF715C_RS00300	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KF715C_RS00325	COG1612	heme a metabolic process
KF715C_RS00330	COG0109	protoheme IX farnesyltransferase activity
KF715C_RS00345	COG2011	ABC-type metal ion transport system permease component
KF715C_RS00350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KF715C_RS00365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KF715C_RS00370	COG1121	(ABC) transporter
KF715C_RS00375	COG0735	belongs to the Fur family
KF715C_RS00380	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KF715C_RS00400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KF715C_RS00405	COG3245	cytochrome
KF715C_RS00415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KF715C_RS00430	COG3023	N-Acetylmuramoyl-L-alanine amidase
KF715C_RS00435	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KF715C_RS00440	COG5002	protein histidine kinase activity
KF715C_RS00445	COG2204	response regulator
KF715C_RS00460	COG5487	UPF0391 membrane protein
KF715C_RS00475	COG1301	dicarboxylic acid transport
KF715C_RS00480	COG3344	reverse transcriptase
KF715C_RS00485	COG0700	Nucleoside recognition
KF715C_RS00500	COG1127	ABC transporter
KF715C_RS00505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KF715C_RS00520	COG1283	sodium-dependent phosphate transmembrane transporter activity
KF715C_RS00525	COG0861	Integral membrane protein TerC family
KF715C_RS00530	COG2851	Citrate transporter
KF715C_RS00565	COG0427	acetyl-CoA hydrolase
KF715C_RS00585	COG0583	DNA-binding transcription factor activity
KF715C_RS00590	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS00650	COG3712	iron ion homeostasis
KF715C_RS00660	COG1802	Transcriptional regulator
KF715C_RS00670	COG5001	Diguanylate cyclase
KF715C_RS00670	COG3300	MHYT domain
KF715C_RS00675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS00695	COG2175	clavaminate synthase activity
KF715C_RS00710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS00730	COG1289	transmembrane transporter activity
KF715C_RS00740	COG1566	PFAM secretion protein HlyD family protein
KF715C_RS00765	COG0672	)-iron permease
KF715C_RS00780	COG0625	glutathione transferase activity
KF715C_RS00785	COG0165	Argininosuccinate lyase
KF715C_RS00795	COG0181	hydroxymethylbilane synthase activity
KF715C_RS00815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KF715C_RS00840	COG0488	(ABC) transporter
KF715C_RS00850	COG1280	lysine exporter protein (LysE YggA)
KF715C_RS00880	COG0517	IMP dehydrogenase activity
KF715C_RS00880	COG0516	GMP reductase activity
KF715C_RS00895	COG2188	Transcriptional regulator
KF715C_RS00900	COG1053	succinate dehydrogenase
KF715C_RS00915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS00940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS00945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS00960	COG4771	TonB-dependent receptor
KF715C_RS00970	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS00975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KF715C_RS00985	COG2199	diguanylate cyclase activity
KF715C_RS01000	COG2011	ABC-type metal ion transport system permease component
KF715C_RS01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KF715C_RS01010	COG1464	Belongs to the NlpA lipoprotein family
KF715C_RS01035	COG1126	abc transporter atp-binding protein
KF715C_RS01040	COG0765	amino acid transport
KF715C_RS01045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS01055	COG1045	serine acetyltransferase
KF715C_RS01060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KF715C_RS01065	COG2175	clavaminate synthase activity
KF715C_RS01070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS01075	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KF715C_RS01080	COG4521	taurine ABC transporter
KF715C_RS01090	COG0450	alkyl hydroperoxide reductase
KF715C_RS01095	COG0431	NADPH-dependent FMN reductase
KF715C_RS01100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS01105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS01110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS01115	COG1116	anion transmembrane transporter activity
KF715C_RS01130	COG2918	glutathione biosynthetic process
KF715C_RS01140	COG2183	response to ionizing radiation
KF715C_RS01155	COG0189	ligase activity
KF715C_RS01160	COG4067	protein conserved in archaea
KF715C_RS01160	COG0189	ligase activity
KF715C_RS01165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KF715C_RS01175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KF715C_RS01180	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KF715C_RS01195	COG0243	molybdopterin cofactor binding
KF715C_RS01200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KF715C_RS01205	COG1652	LysM domain
KF715C_RS01210	COG1011	Hydrolase
KF715C_RS01215	COG0494	nUDIX hydrolase
KF715C_RS01245	COG2957	Belongs to the agmatine deiminase family
KF715C_RS01265	COG0069	glutamate synthase activity
KF715C_RS01295	COG2199	diguanylate cyclase activity
KF715C_RS01295	COG2203	Gaf domain
KF715C_RS01330	COG0582	viral genome integration into host DNA
KF715C_RS01530	COG4695	Portal protein
KF715C_RS01550	COG3617	BRO family, N-terminal domain
KF715C_RS01580	COG4215	(ABC) transporter
KF715C_RS01620	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KF715C_RS01635	COG2223	nitrite transmembrane transporter activity
KF715C_RS01640	COG0131	Imidazoleglycerol-phosphate dehydratase
KF715C_RS01645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KF715C_RS01655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KF715C_RS01660	COG0107	imidazoleglycerol-phosphate synthase activity
KF715C_RS01665	COG4175	Glycine betaine
KF715C_RS01665	COG3448	diguanylate cyclase activity
KF715C_RS01670	COG4176	ABC-type proline glycine betaine transport system permease component
KF715C_RS01680	COG1760	l-serine dehydratase
KF715C_RS01700	COG1250	3-hydroxyacyl-CoA dehydrogenase
KF715C_RS01705	COG3246	L-lysine catabolic process to acetate
KF715C_RS01735	COG0446	pyridine nucleotide-disulphide oxidoreductase
KF715C_RS01735	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS01740	COG2181	nitrate reductase activity
KF715C_RS01740	COG0247	lactate metabolic process
KF715C_RS01745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KF715C_RS01760	COG4638	Rieske (2fe-2S)
KF715C_RS01770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KF715C_RS01770	COG1017	nitric oxide dioxygenase activity
KF715C_RS01795	COG0840	transmembrane signaling receptor activity
KF715C_RS01805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KF715C_RS01835	COG1063	alcohol dehydrogenase
KF715C_RS01850	COG0531	amino acid
KF715C_RS01855	COG0204	Acyl-transferase
KF715C_RS01865	COG0745	RESPONSE REGULATOR receiver
KF715C_RS01870	COG2205	protein histidine kinase activity
KF715C_RS01875	COG4452	Inner membrane protein CreD
KF715C_RS01885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KF715C_RS01905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KF715C_RS01920	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS01960	COG4774	siderophore transport
KF715C_RS01965	COG3712	iron ion homeostasis
KF715C_RS01970	COG1595	DNA-templated transcription, initiation
KF715C_RS01975	COG2176	DNA-directed DNA polymerase activity
KF715C_RS01980	COG0517	IMP dehydrogenase activity
KF715C_RS01980	COG1125	glycine betaine transport
KF715C_RS01990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KF715C_RS02005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KF715C_RS02010	COG3585	molybdate ion transport
KF715C_RS02010	COG2005	Transcriptional regulator
KF715C_RS02015	COG1040	competence protein
KF715C_RS02020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KF715C_RS02025	COG0156	8-amino-7-oxononanoate synthase activity
KF715C_RS02030	COG2267	carboxylic ester hydrolase activity
KF715C_RS02050	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS02055	COG3706	GGDEF domain
KF715C_RS02060	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS02065	COG0583	DNA-binding transcription factor activity
KF715C_RS02070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KF715C_RS02090	COG0535	radical SAM domain protein
KF715C_RS02100	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KF715C_RS02105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KF715C_RS02115	COG1025	Belongs to the peptidase M16 family
KF715C_RS02120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KF715C_RS02155	COG0358	DNA primase activity
KF715C_RS02160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KF715C_RS02165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KF715C_RS02170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KF715C_RS02175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KF715C_RS02185	COG0617	tRNA 3'-terminal CCA addition
KF715C_RS02190	COG2719	SpoVR family
KF715C_RS02195	COG2718	Belongs to the UPF0229 family
KF715C_RS02200	COG2766	serine protein kinase
KF715C_RS02205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KF715C_RS02210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KF715C_RS02215	COG2967	ApaG domain
KF715C_RS02220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KF715C_RS02225	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KF715C_RS02230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KF715C_RS02235	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KF715C_RS02240	COG3178	'Phosphotransferase
KF715C_RS02245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KF715C_RS02250	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KF715C_RS02265	COG2197	response regulator
KF715C_RS02270	COG3842	ATPase activity
KF715C_RS02280	COG1176	ABC-type spermidine putrescine transport system, permease component I
KF715C_RS02290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KF715C_RS02295	COG0546	phosphoglycolate phosphatase activity
KF715C_RS02300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KF715C_RS02305	COG3240	lipase activity
KF715C_RS02305	COG4625	pathogenesis
KF715C_RS02310	COG0512	Glutamine amidotransferase of anthranilate synthase
KF715C_RS02315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KF715C_RS02320	COG0134	indole-3-glycerol-phosphate synthase activity
KF715C_RS02335	COG1765	OsmC-like protein
KF715C_RS02345	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KF715C_RS02350	COG0537	adenosine 5'-monophosphoramidase activity
KF715C_RS02355	COG0300	oxidoreductase activity
KF715C_RS02360	COG2070	2-Nitropropane dioxygenase
KF715C_RS02365	COG1981	membrane
KF715C_RS02370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KF715C_RS02375	COG0316	Belongs to the HesB IscA family
KF715C_RS02380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KF715C_RS02385	COG0739	heme binding
KF715C_RS02390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KF715C_RS02410	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KF715C_RS02410	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KF715C_RS02415	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KF715C_RS02440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KF715C_RS02460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KF715C_RS02465	COG0081	regulation of translation
KF715C_RS02470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KF715C_RS02475	COG0222	ribosome binding
KF715C_RS02480	COG0085	RNA polymerase activity
KF715C_RS02485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KF715C_RS02490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KF715C_RS02495	COG0049	tRNA binding
KF715C_RS02500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KF715C_RS02505	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KF715C_RS02510	COG0051	transcription antitermination factor activity, RNA binding
KF715C_RS02515	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KF715C_RS02520	COG0088	Forms part of the polypeptide exit tunnel
KF715C_RS02525	COG0089	rRNA binding
KF715C_RS02530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KF715C_RS02535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KF715C_RS02540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KF715C_RS02545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KF715C_RS02550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KF715C_RS02555	COG0255	Belongs to the universal ribosomal protein uL29 family
KF715C_RS02560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KF715C_RS02565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KF715C_RS02570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KF715C_RS02575	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KF715C_RS02580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KF715C_RS02585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KF715C_RS02590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KF715C_RS02595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KF715C_RS02600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KF715C_RS02605	COG1841	ribosomal large subunit assembly
KF715C_RS02610	COG0200	Binds to the 23S rRNA
KF715C_RS02620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KF715C_RS02625	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KF715C_RS02630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KF715C_RS02635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KF715C_RS02640	COG0202	RNA polymerase activity
KF715C_RS02645	COG0203	ribosomal protein L17
KF715C_RS02650	COG0753	catalase activity
KF715C_RS02655	COG2193	ferroxidase activity
KF715C_RS02660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KF715C_RS02665	COG2814	Major facilitator Superfamily
KF715C_RS02670	COG0629	single-stranded DNA binding
KF715C_RS02675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS02685	COG0730	response to heat
KF715C_RS02690	COG4221	oxidoreductase activity
KF715C_RS02695	COG3383	formate dehydrogenase (NAD+) activity
KF715C_RS02695	COG0243	molybdopterin cofactor binding
KF715C_RS02700	COG0243	molybdopterin cofactor binding
KF715C_RS02700	COG3383	formate dehydrogenase (NAD+) activity
KF715C_RS02705	COG0437	4 iron, 4 sulfur cluster binding
KF715C_RS02710	COG2864	formate dehydrogenase
KF715C_RS02715	COG3058	Necessary for formate dehydrogenase activity
KF715C_RS02720	COG1921	L-seryl-tRNASec selenium transferase activity
KF715C_RS02725	COG3276	selenocysteine insertion sequence binding
KF715C_RS02735	COG0252	asparaginase activity
KF715C_RS02740	COG1115	amino acid carrier protein
KF715C_RS02780	COG2814	Major facilitator Superfamily
KF715C_RS02785	COG3047	cAMP biosynthetic process
KF715C_RS02815	COG3118	belongs to the thioredoxin family
KF715C_RS02820	COG2264	protein methyltransferase activity
KF715C_RS02835	COG3344	reverse transcriptase
KF715C_RS02840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KF715C_RS02845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KF715C_RS02845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KF715C_RS02860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KF715C_RS02865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KF715C_RS02870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KF715C_RS02875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KF715C_RS02885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KF715C_RS02895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KF715C_RS02900	COG4206	TonB-dependent receptor
KF715C_RS02905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KF715C_RS02910	COG0142	geranyltranstransferase activity
KF715C_RS02915	COG1722	exodeoxyribonuclease VII activity
KF715C_RS02920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KF715C_RS02925	COG1690	Belongs to the RtcB family
KF715C_RS02935	COG2819	hydrolase of the alpha beta superfamily
KF715C_RS02965	COG1595	DNA-templated transcription, initiation
KF715C_RS02970	COG4206	TonB-dependent receptor
KF715C_RS02970	COG1629	transport
KF715C_RS03005	COG3971	2-oxopent-4-enoate hydratase activity
KF715C_RS03045	COG1063	alcohol dehydrogenase
KF715C_RS03075	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KF715C_RS03080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KF715C_RS03085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KF715C_RS03145	COG0666	response to abiotic stimulus
KF715C_RS03160	COG3012	SEC-C Motif Domain Protein
KF715C_RS03175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KF715C_RS03180	COG0732	type I restriction modification DNA specificity domain
KF715C_RS03230	COG2003	Belongs to the UPF0758 family
KF715C_RS03265	COG0582	viral genome integration into host DNA
KF715C_RS03275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KF715C_RS03280	COG3228	Belongs to the MtfA family
KF715C_RS03285	COG0586	Pfam SNARE associated Golgi protein
KF715C_RS03290	COG0456	acetyltransferase
KF715C_RS03295	COG4302	ethanolamine ammonia-lyase activity
KF715C_RS03300	COG4303	Ethanolamine ammonia lyase large subunit
KF715C_RS03305	COG0531	amino acid
KF715C_RS03315	COG3284	Transcriptional regulator
KF715C_RS03320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KF715C_RS03335	COG0702	epimerase
KF715C_RS03345	COG1063	alcohol dehydrogenase
KF715C_RS03355	COG0022	dehydrogenase e1 component
KF715C_RS03360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KF715C_RS03365	COG3199	ATP-NAD kinase
KF715C_RS03370	COG3284	Transcriptional regulator
KF715C_RS03385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KF715C_RS03415	COG0023	Translation Initiation Factor
KF715C_RS03420	COG1166	arginine decarboxylase activity
KF715C_RS03425	COG0534	Mate efflux family protein
KF715C_RS03430	COG2373	Large extracellular alpha-helical protein
KF715C_RS03440	COG4953	penicillin-binding protein 1C
KF715C_RS03475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KF715C_RS03485	COG2030	dehydratase
KF715C_RS03490	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS03500	COG2207	Transcriptional regulator
KF715C_RS03515	COG2217	Heavy metal translocating P-type atpase
KF715C_RS03530	COG2814	Major facilitator Superfamily
KF715C_RS03545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KF715C_RS03550	COG0300	oxidoreductase activity
KF715C_RS03555	COG1739	Uncharacterized protein family UPF0029
KF715C_RS03560	COG1309	transcriptional regulator
KF715C_RS03595	COG2995	paraquat-inducible protein a
KF715C_RS03600	COG2995	paraquat-inducible protein a
KF715C_RS03605	COG3008	intermembrane lipid transfer
KF715C_RS03610	COG0268	Binds directly to 16S ribosomal RNA
KF715C_RS03620	COG0196	riboflavin kinase activity
KF715C_RS03625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KF715C_RS03630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KF715C_RS03635	COG1047	Peptidyl-prolyl cis-trans
KF715C_RS03640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KF715C_RS03670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS03695	COG0542	response to heat
KF715C_RS03700	COG3344	reverse transcriptase
KF715C_RS03720	COG1252	NADH dehydrogenase
KF715C_RS03740	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KF715C_RS03745	COG0237	dephospho-CoA kinase activity
KF715C_RS03770	COG0582	viral genome integration into host DNA
KF715C_RS03785	COG2826	transposase and inactivated derivatives, IS30 family
KF715C_RS03840	COG0039	L-malate dehydrogenase activity
KF715C_RS03855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KF715C_RS03865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KF715C_RS03880	COG0488	(ABC) transporter
KF715C_RS03885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KF715C_RS03890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KF715C_RS03915	COG1067	ATP-dependent peptidase activity
KF715C_RS03925	COG2862	Uncharacterized protein family, UPF0114
KF715C_RS03935	COG0545	Peptidyl-prolyl cis-trans isomerase
KF715C_RS03945	COG2824	Alkylphosphonate utilization operon protein PhnA
KF715C_RS03950	COG0142	geranyltranstransferase activity
KF715C_RS03955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KF715C_RS03960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KF715C_RS03965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KF715C_RS03970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KF715C_RS03975	COG3045	CreA protein
KF715C_RS04000	COG0456	acetyltransferase
KF715C_RS04030	COG2223	nitrite transmembrane transporter activity
KF715C_RS04045	COG1595	DNA-templated transcription, initiation
KF715C_RS04055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KF715C_RS04055	COG2169	Transcriptional regulator
KF715C_RS04060	COG1511	domain protein
KF715C_RS04060	COG3264	Mechanosensitive ion channel
KF715C_RS04090	COG1335	isochorismatase
KF715C_RS04105	COG0628	permease
KF715C_RS04230	COG2826	transposase and inactivated derivatives, IS30 family
KF715C_RS04245	COG0583	DNA-binding transcription factor activity
KF715C_RS04250	COG5285	phytanoyl-CoA dioxygenase
KF715C_RS04255	COG2271	Major facilitator Superfamily
KF715C_RS04260	COG3039	Transposase
KF715C_RS04280	COG3829	transcription factor binding
KF715C_RS04285	COG1454	alcohol dehydrogenase
KF715C_RS04295	COG3039	Transposase
KF715C_RS04305	COG1454	alcohol dehydrogenase
KF715C_RS04310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KF715C_RS04445	COG2003	Belongs to the UPF0758 family
KF715C_RS04455	COG5377	YqaJ viral recombinase family
KF715C_RS04460	COG0582	viral genome integration into host DNA
KF715C_RS04470	COG0193	aminoacyl-tRNA hydrolase activity
KF715C_RS04475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KF715C_RS04480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KF715C_RS04490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KF715C_RS04495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KF715C_RS04505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KF715C_RS04510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KF715C_RS04520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KF715C_RS04525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KF715C_RS04540	COG0415	Belongs to the DNA photolyase family
KF715C_RS04545	COG0789	Transcriptional regulator
KF715C_RS04555	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
KF715C_RS04560	COG1090	epimerase
KF715C_RS04565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KF715C_RS04575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KF715C_RS04580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KF715C_RS04595	COG0579	oxidoreductase
KF715C_RS04635	COG2135	peptidase activity
KF715C_RS04645	COG2119	membrane
KF715C_RS04650	COG2813	Specifically methylates the guanine in position
KF715C_RS04655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KF715C_RS04660	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS04695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KF715C_RS04700	COG2885	chlorophyll binding
KF715C_RS04705	COG0857	belongs to the CobB CobQ family
KF715C_RS04705	COG0280	phosphate acetyltransferase
KF715C_RS04720	COG0386	Belongs to the glutathione peroxidase family
KF715C_RS04735	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KF715C_RS04740	COG0492	ferredoxin-NADP+ reductase activity
KF715C_RS04755	COG3023	N-Acetylmuramoyl-L-alanine amidase
KF715C_RS04760	COG3725	Membrane protein required for beta-lactamase induction
KF715C_RS04765	COG0084	hydrolase, TatD family'
KF715C_RS04770	COG1609	Transcriptional regulator
KF715C_RS04780	COG1105	Belongs to the carbohydrate kinase PfkB family
KF715C_RS04785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KF715C_RS04785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KF715C_RS04785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KF715C_RS04790	COG3530	Putative quorum-sensing-regulated virulence factor
KF715C_RS04800	COG4251	negative regulation of phosphorylation
KF715C_RS04800	COG5001	Diguanylate cyclase
KF715C_RS04800	COG2203	Gaf domain
KF715C_RS04800	COG3706	GGDEF domain
KF715C_RS04825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS04870	COG3604	Transcriptional regulator
KF715C_RS04875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KF715C_RS04875	COG1017	nitric oxide dioxygenase activity
KF715C_RS04885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KF715C_RS04895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KF715C_RS04900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KF715C_RS04905	COG1845	cytochrome c oxidase, subunit III
KF715C_RS04910	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KF715C_RS04915	COG0109	protoheme IX farnesyltransferase activity
KF715C_RS04920	COG0436	Aminotransferase
KF715C_RS04930	COG0727	PFAM Uncharacterised protein family (UPF0153)
KF715C_RS04935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KF715C_RS04940	COG1595	DNA-templated transcription, initiation
KF715C_RS04965	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KF715C_RS04970	COG0709	Synthesizes selenophosphate from selenide and ATP
KF715C_RS04975	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KF715C_RS04980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KF715C_RS04985	COG3639	organic phosphonate transmembrane transporter activity
KF715C_RS04990	COG3639	organic phosphonate transmembrane transporter activity
KF715C_RS04995	COG3781	membrane
KF715C_RS05000	COG3657	addiction module killer protein
KF715C_RS05025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS05070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KF715C_RS05075	COG0343	queuine tRNA-ribosyltransferase activity
KF715C_RS05080	COG1862	Preprotein translocase
KF715C_RS05095	COG3134	Outer membrane lipoprotein
KF715C_RS05110	COG1045	serine acetyltransferase
KF715C_RS05120	COG1104	cysteine desulfurase activity
KF715C_RS05130	COG0316	Belongs to the HesB IscA family
KF715C_RS05135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KF715C_RS05140	COG0443	Heat shock 70 kDa protein
KF715C_RS05145	COG0633	Ferredoxin
KF715C_RS05155	COG0105	UTP biosynthetic process
KF715C_RS05160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KF715C_RS05175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KF715C_RS05180	COG0124	histidyl-tRNA synthetase
KF715C_RS05195	COG1160	GTP binding
KF715C_RS05200	COG0436	Aminotransferase
KF715C_RS05210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KF715C_RS05215	COG4774	siderophore transport
KF715C_RS05220	COG3128	pkhd-type hydroxylase
KF715C_RS05230	COG0019	diaminopimelate decarboxylase activity
KF715C_RS05245	COG4772	TonB-dependent receptor
KF715C_RS05270	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KF715C_RS05285	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KF715C_RS05300	COG4608	Belongs to the ABC transporter superfamily
KF715C_RS05305	COG0444	Belongs to the ABC transporter superfamily
KF715C_RS05310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KF715C_RS05315	COG0601	transmembrane transport
KF715C_RS05320	COG0747	negative chemotaxis
KF715C_RS05330	COG0747	negative chemotaxis
KF715C_RS05335	COG0747	negative chemotaxis
KF715C_RS05350	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KF715C_RS05360	COG1113	amino acid transport
KF715C_RS05375	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KF715C_RS05380	COG0154	amidase activity
KF715C_RS05385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KF715C_RS05390	COG1077	Cell shape determining protein MreB Mrl
KF715C_RS05395	COG1792	Involved in formation and maintenance of cell shape
KF715C_RS05405	COG0424	maF-like protein
KF715C_RS05420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KF715C_RS05425	COG0312	modulator of DNA gyrase
KF715C_RS05430	COG3028	Belongs to the UPF0307 family
KF715C_RS05435	COG0312	modulator of DNA gyrase
KF715C_RS05465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KF715C_RS05470	COG1660	Displays ATPase and GTPase activities
KF715C_RS05480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KF715C_RS05485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KF715C_RS05490	COG1137	ATPase activity
KF715C_RS05495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KF715C_RS05505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KF715C_RS05515	COG1127	ABC transporter
KF715C_RS05520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KF715C_RS05525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KF715C_RS05545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KF715C_RS05550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KF715C_RS05555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KF715C_RS05560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KF715C_RS05565	COG2186	Transcriptional regulator
KF715C_RS05570	COG2807	transmembrane transport
KF715C_RS05585	COG2827	Endonuclease containing a URI domain
KF715C_RS05590	COG3081	Nucleoid-associated protein
KF715C_RS05650	COG3081	Nucleoid-associated protein
KF715C_RS05675	COG3081	Nucleoid-associated protein
KF715C_RS05680	COG0776	regulation of translation
KF715C_RS05685	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KF715C_RS05690	COG0525	valine-tRNA ligase activity
KF715C_RS05705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KF715C_RS05715	COG0795	lipopolysaccharide-transporting ATPase activity
KF715C_RS05720	COG0795	lipopolysaccharide-transporting ATPase activity
KF715C_RS05730	COG1278	Cold shock
KF715C_RS05735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KF715C_RS05740	COG1760	l-serine dehydratase
KF715C_RS05745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KF715C_RS05745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KF715C_RS05750	COG0509	glycine decarboxylation via glycine cleavage system
KF715C_RS05765	COG0786	glutamate:sodium symporter activity
KF715C_RS05785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KF715C_RS05790	COG2235	arginine
KF715C_RS05805	COG2832	Protein of unknown function (DUF454)
KF715C_RS05860	COG1653	transport
KF715C_RS05865	COG1175	transmembrane transport
KF715C_RS05875	COG3842	ATPase activity
KF715C_RS05885	COG0676	glucose-6-phosphate 1-epimerase activity
KF715C_RS05890	COG1737	Transcriptional regulator
KF715C_RS05905	COG0800	Aldolase
KF715C_RS05910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KF715C_RS05915	COG0739	heme binding
KF715C_RS05920	COG1570	exodeoxyribonuclease VII activity
KF715C_RS05925	COG0583	DNA-binding transcription factor activity
KF715C_RS05945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KF715C_RS05945	COG0519	Catalyzes the synthesis of GMP from XMP
KF715C_RS05955	COG0590	tRNA wobble adenosine to inosine editing
KF715C_RS05960	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KF715C_RS05965	COG0047	phosphoribosylformylglycinamidine synthase activity
KF715C_RS05965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KF715C_RS05980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KF715C_RS06015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KF715C_RS06100	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KF715C_RS06105	COG0477	Major facilitator Superfamily
KF715C_RS06110	COG4536	flavin adenine dinucleotide binding
KF715C_RS06120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KF715C_RS06125	COG0228	four-way junction DNA binding
KF715C_RS06130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KF715C_RS06135	COG0336	Belongs to the RNA methyltransferase TrmD family
KF715C_RS06140	COG0335	large ribosomal subunit rRNA binding
KF715C_RS06145	COG1607	acyl-coa hydrolase
KF715C_RS06150	COG4974	Belongs to the 'phage' integrase family
KF715C_RS06185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KF715C_RS06200	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS06205	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS06210	COG1177	transmembrane transport
KF715C_RS06215	COG1176	ABC-type spermidine putrescine transport system, permease component I
KF715C_RS06220	COG3842	ATPase activity
KF715C_RS06225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KF715C_RS06230	COG2979	Protein of unknown function (DUF533)
KF715C_RS06235	COG0840	transmembrane signaling receptor activity
KF715C_RS06245	COG0457	Tetratricopeptide repeat
KF715C_RS06245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KF715C_RS06260	COG2201	protein-glutamate methylesterase activity
KF715C_RS06265	COG5001	Diguanylate cyclase
KF715C_RS06265	COG4251	negative regulation of phosphorylation
KF715C_RS06265	COG3706	GGDEF domain
KF715C_RS06265	COG2203	Gaf domain
KF715C_RS06275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KF715C_RS06305	COG2885	chlorophyll binding
KF715C_RS06320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KF715C_RS06325	COG0563	adenylate kinase activity
KF715C_RS06360	COG0742	ribosomal rna small subunit methyltransferase
KF715C_RS06370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS06390	COG2937	Belongs to the GPAT DAPAT family
KF715C_RS06405	COG2226	methyltransferase
KF715C_RS06410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KF715C_RS06415	COG1215	transferase activity, transferring glycosyl groups
KF715C_RS06420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KF715C_RS06430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KF715C_RS06435	COG2171	N-acyltransferase activity
KF715C_RS06440	COG1393	Belongs to the ArsC family
KF715C_RS06450	COG0025	NhaP-type Na H and K H
KF715C_RS06455	COG0436	Aminotransferase
KF715C_RS06460	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KF715C_RS06465	COG0024	Methionine aminopeptidase
KF715C_RS06470	COG0052	Belongs to the universal ribosomal protein uS2 family
KF715C_RS06475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KF715C_RS06480	COG0528	UMP kinase activity
KF715C_RS06485	COG0233	cytoplasmic translational termination
KF715C_RS06490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KF715C_RS06500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KF715C_RS06520	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KF715C_RS06525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KF715C_RS06530	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KF715C_RS06535	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KF715C_RS06540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KF715C_RS06550	COG0825	malonyl-CoA metabolic process
KF715C_RS06555	COG0037	tRNA processing
KF715C_RS06560	COG0504	CTP synthase activity
KF715C_RS06565	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KF715C_RS06570	COG0148	phosphopyruvate hydratase activity
KF715C_RS06580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KF715C_RS06590	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KF715C_RS06600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KF715C_RS06605	COG0585	pseudouridine synthase activity
KF715C_RS06610	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KF715C_RS06615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KF715C_RS06630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KF715C_RS06635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KF715C_RS06645	COG1546	Belongs to the CinA family
KF715C_RS06670	COG2826	transposase and inactivated derivatives, IS30 family
KF715C_RS06730	COG1172	Belongs to the binding-protein-dependent transport system permease family
KF715C_RS06770	COG4372	Transposase
KF715C_RS06790	COG3436	PFAM IS66 Orf2 family protein
KF715C_RS06805	COG3344	reverse transcriptase
KF715C_RS06825	COG4372	Transposase
KF715C_RS06860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KF715C_RS06865	COG2137	regulation of response to DNA damage stimulus
KF715C_RS06885	COG3148	PFAM DTW domain containing protein
KF715C_RS06900	COG0583	DNA-binding transcription factor activity
KF715C_RS06910	COG3091	SprT-like family
KF715C_RS06920	COG0037	tRNA processing
KF715C_RS06960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KF715C_RS06965	COG0784	Response regulator, receiver
KF715C_RS06965	COG2205	protein histidine kinase activity
KF715C_RS06965	COG5002	protein histidine kinase activity
KF715C_RS06985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KF715C_RS06990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KF715C_RS06995	COG3956	TIGRFAM MazG family protein
KF715C_RS07000	COG3122	Protein conserved in bacteria
KF715C_RS07015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KF715C_RS07020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KF715C_RS07030	COG0628	permease
KF715C_RS07040	COG0791	NLP P60 protein
KF715C_RS07045	COG0791	NLP P60 protein
KF715C_RS07065	COG1797	cobyrinic acid a,c-diamide synthase activity
KF715C_RS07070	COG0778	Nitroreductase
KF715C_RS07085	COG1492	cobalamin metabolic process
KF715C_RS07095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KF715C_RS07105	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KF715C_RS07115	COG1846	Transcriptional regulator
KF715C_RS07140	COG0583	DNA-binding transcription factor activity
KF715C_RS07170	COG2205	protein histidine kinase activity
KF715C_RS07175	COG2814	Major facilitator Superfamily
KF715C_RS07180	COG0477	Major facilitator Superfamily
KF715C_RS07185	COG2076	Multidrug Resistance protein
KF715C_RS07190	COG0385	Bile acid
KF715C_RS07195	COG2974	May be involved in recombination
KF715C_RS07220	COG0024	Methionine aminopeptidase
KF715C_RS07225	COG0243	molybdopterin cofactor binding
KF715C_RS07230	COG2146	nitrite reductase [NAD(P)H] activity
KF715C_RS07230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KF715C_RS07235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KF715C_RS07235	COG2146	nitrite reductase [NAD(P)H] activity
KF715C_RS07240	COG0583	DNA-binding transcription factor activity
KF715C_RS07250	COG0545	Peptidyl-prolyl cis-trans isomerase
KF715C_RS07255	COG3339	Conserved Protein
KF715C_RS07270	COG3300	MHYT domain
KF715C_RS07270	COG5001	Diguanylate cyclase
KF715C_RS07300	COG1176	ABC-type spermidine putrescine transport system, permease component I
KF715C_RS07320	COG0668	transmembrane transport
KF715C_RS07330	COG1362	aminopeptidase activity
KF715C_RS07335	COG0564	pseudouridine synthase activity
KF715C_RS07345	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KF715C_RS07350	COG2894	cell division
KF715C_RS07355	COG0850	regulation of cytokinetic process
KF715C_RS07360	COG1560	Kdo2-lipid A biosynthetic process
KF715C_RS07370	COG2853	Lipoprotein
KF715C_RS07390	COG2113	Glycine betaine
KF715C_RS07395	COG3162	membrane
KF715C_RS07400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KF715C_RS07420	COG3089	Belongs to the UPF0270 family
KF715C_RS07425	COG1363	Peptidase, m42
KF715C_RS07430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KF715C_RS07430	COG0189	ligase activity
KF715C_RS07435	COG0367	asparagine synthase
KF715C_RS07440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KF715C_RS07440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS07445	COG2326	polyphosphate kinase activity
KF715C_RS07450	COG0697	spore germination
KF715C_RS07455	COG0114	fumarate hydratase activity
KF715C_RS07465	COG0271	Belongs to the BolA IbaG family
KF715C_RS07470	COG1054	Belongs to the UPF0176 family
KF715C_RS07485	COG5001	Diguanylate cyclase
KF715C_RS07485	COG5002	protein histidine kinase activity
KF715C_RS07495	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS07500	COG0546	phosphoglycolate phosphatase activity
KF715C_RS07505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KF715C_RS07510	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KF715C_RS07520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KF715C_RS07530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KF715C_RS07535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KF715C_RS07545	COG0776	regulation of translation
KF715C_RS07555	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KF715C_RS07565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KF715C_RS07580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KF715C_RS07595	COG0463	Glycosyl transferase, family 2
KF715C_RS07650	COG1083	cytidylyl-transferase
KF715C_RS07655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KF715C_RS07660	COG1216	Glycosyl transferase, family 2
KF715C_RS07660	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS07685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS07695	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KF715C_RS07705	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS07720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KF715C_RS07735	COG0166	Belongs to the GPI family
KF715C_RS07740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KF715C_RS07745	COG1555	photosystem II stabilization
KF715C_RS07755	COG0284	orotidine-5'-phosphate decarboxylase activity
KF715C_RS07760	COG2130	NADP-dependent
KF715C_RS07770	COG0840	transmembrane signaling receptor activity
KF715C_RS07775	COG3135	benzoate transporter
KF715C_RS07780	COG0625	glutathione transferase activity
KF715C_RS07790	COG0302	gtp cyclohydrolase
KF715C_RS07795	COG2840	Smr protein MutS2
KF715C_RS07825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KF715C_RS07830	COG2814	Major facilitator Superfamily
KF715C_RS07835	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KF715C_RS07870	COG1368	sulfuric ester hydrolase activity
KF715C_RS07890	COG0519	Catalyzes the synthesis of GMP from XMP
KF715C_RS07895	COG0598	Magnesium transport protein CorA
KF715C_RS07925	COG2814	Major facilitator Superfamily
KF715C_RS07930	COG0583	DNA-binding transcription factor activity
KF715C_RS07935	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS07940	COG0583	DNA-binding transcription factor activity
KF715C_RS07960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KF715C_RS07965	COG1764	response to oxidative stress
KF715C_RS07970	COG1846	Transcriptional regulator
KF715C_RS07975	COG0583	DNA-binding transcription factor activity
KF715C_RS07985	COG0583	DNA-binding transcription factor activity
KF715C_RS07995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KF715C_RS08010	COG3384	dioxygenase
KF715C_RS08015	COG0500	methyltransferase
KF715C_RS08020	COG0501	Belongs to the peptidase M48B family
KF715C_RS08025	COG0436	Aminotransferase
KF715C_RS08030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KF715C_RS08035	COG0386	Belongs to the glutathione peroxidase family
KF715C_RS08040	COG3437	response regulator, receiver
KF715C_RS08040	COG3850	Histidine kinase
KF715C_RS08040	COG2205	protein histidine kinase activity
KF715C_RS08040	COG4999	Histidine kinase
KF715C_RS08050	COG1956	GAF domain-containing protein
KF715C_RS08090	COG3188	usher protein
KF715C_RS08150	COG3121	Chaperone
KF715C_RS08175	COG0625	glutathione transferase activity
KF715C_RS08180	COG1131	(ABC) transporter
KF715C_RS08185	COG0842	Transport permease protein
KF715C_RS08195	COG0658	competence protein
KF715C_RS08195	COG2333	competence protein COMEC
KF715C_RS08200	COG0811	peptide transport
KF715C_RS08205	COG0848	biopolymer transport protein
KF715C_RS08210	COG1663	tetraacyldisaccharide 4'-kinase activity
KF715C_RS08215	COG2835	tetraacyldisaccharide 4'-kinase activity
KF715C_RS08220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KF715C_RS08225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KF715C_RS08230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KF715C_RS08235	COG1530	ribonuclease E activity
KF715C_RS08250	COG0546	phosphoglycolate phosphatase activity
KF715C_RS08255	COG0616	signal peptide processing
KF715C_RS08255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KF715C_RS08260	COG0424	maF-like protein
KF715C_RS08265	COG1399	metal-binding, possibly nucleic acid-binding protein
KF715C_RS08270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KF715C_RS08275	COG0416	fatty acid biosynthetic process
KF715C_RS08290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KF715C_RS08295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KF715C_RS08305	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KF715C_RS08310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KF715C_RS08320	COG0084	hydrolase, TatD family'
KF715C_RS08335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KF715C_RS08365	COG0556	nucleotide-excision repair
KF715C_RS08380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KF715C_RS08420	COG2267	carboxylic ester hydrolase activity
KF715C_RS08430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KF715C_RS08450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KF715C_RS08455	COG0066	3-isopropylmalate dehydratase activity
KF715C_RS08460	COG2226	methyltransferase
KF715C_RS08465	COG0473	3-isopropylmalate dehydrogenase activity
KF715C_RS08490	COG0135	phosphoribosylanthranilate isomerase activity
KF715C_RS08495	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KF715C_RS08500	COG0285	dihydrofolate synthase activity
KF715C_RS08510	COG1286	toxin biosynthetic process
KF715C_RS08565	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS08565	COG0446	pyridine nucleotide-disulphide oxidoreductase
KF715C_RS08575	COG3038	cytochrome b561
KF715C_RS08585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KF715C_RS08590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KF715C_RS08595	COG0705	Rhomboid family
KF715C_RS08600	COG3139	Protein of unknown function (DUF1315)
KF715C_RS08610	COG0308	aminopeptidase N
KF715C_RS08630	COG2706	6-phosphogluconolactonase activity
KF715C_RS08650	COG0420	3'-5' exonuclease activity
KF715C_RS08680	COG0714	Associated with various cellular activities
KF715C_RS08695	COG3135	benzoate transporter
KF715C_RS08700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KF715C_RS08725	COG0583	DNA-binding transcription factor activity
KF715C_RS08730	COG2828	Protein conserved in bacteria
KF715C_RS08735	COG1301	dicarboxylic acid transport
KF715C_RS08740	COG2851	Citrate transporter
KF715C_RS08750	COG3237	CsbD-like
KF715C_RS08755	COG0789	Transcriptional regulator
KF715C_RS08765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS08770	COG2188	Transcriptional regulator
KF715C_RS08785	COG1538	Outer membrane efflux protein
KF715C_RS08820	COG1595	DNA-templated transcription, initiation
KF715C_RS08830	COG0019	diaminopimelate decarboxylase activity
KF715C_RS08835	COG0583	DNA-binding transcription factor activity
KF715C_RS08850	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KF715C_RS08865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KF715C_RS08880	COG0668	transmembrane transport
KF715C_RS08895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KF715C_RS08905	COG2223	nitrite transmembrane transporter activity
KF715C_RS08910	COG3707	response regulator
KF715C_RS08915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS08915	COG1116	anion transmembrane transporter activity
KF715C_RS08920	COG0167	dihydroorotate dehydrogenase activity
KF715C_RS08925	COG3130	regulation of translation
KF715C_RS08930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KF715C_RS08930	COG0116	Belongs to the methyltransferase superfamily
KF715C_RS08940	COG2027	D-alanyl-D-alanine carboxypeptidase
KF715C_RS08945	COG3171	Protein conserved in bacteria
KF715C_RS08955	COG2197	response regulator
KF715C_RS08980	COG0004	ammonium transporteR
KF715C_RS09005	COG0840	transmembrane signaling receptor activity
KF715C_RS09015	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KF715C_RS09025	COG0425	Belongs to the sulfur carrier protein TusA family
KF715C_RS09030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KF715C_RS09035	COG1132	(ABC) transporter
KF715C_RS09055	COG0521	Mo-molybdopterin cofactor biosynthetic process
KF715C_RS09070	COG1597	lipid kinase activity
KF715C_RS09075	COG2197	response regulator
KF715C_RS09080	COG3851	Histidine kinase
KF715C_RS09090	COG0784	Response regulator, receiver
KF715C_RS09090	COG0835	chemotaxis
KF715C_RS09100	COG0741	lytic transglycosylase activity
KF715C_RS09105	COG0488	(ABC) transporter
KF715C_RS09110	COG0589	response to stress
KF715C_RS09120	COG1250	3-hydroxyacyl-CoA dehydrogenase
KF715C_RS09120	COG1024	Enoyl-CoA hydratase
KF715C_RS09125	COG0183	Belongs to the thiolase family
KF715C_RS09155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KF715C_RS09165	COG1376	ErfK ybiS ycfS ynhG family protein
KF715C_RS09175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KF715C_RS09185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KF715C_RS09195	COG1477	protein flavinylation
KF715C_RS09200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KF715C_RS09205	COG0584	glycerophosphoryl diester phosphodiesterase
KF715C_RS09215	COG4591	ABC-type transport system involved in lipoprotein release permease component
KF715C_RS09220	COG1136	(ABC) transporter
KF715C_RS09225	COG4591	ABC-type transport system involved in lipoprotein release permease component
KF715C_RS09245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KF715C_RS09245	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KF715C_RS09260	COG2853	Lipoprotein
KF715C_RS09270	COG4566	intracellular signal transduction
KF715C_RS09285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KF715C_RS09290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KF715C_RS09305	COG1595	DNA-templated transcription, initiation
KF715C_RS09330	COG0402	S-adenosylhomocysteine deaminase activity
KF715C_RS09340	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KF715C_RS09350	COG0583	DNA-binding transcription factor activity
KF715C_RS09360	COG1605	Chorismate mutase
KF715C_RS09360	COG0077	Prephenate dehydratase
KF715C_RS09385	COG3712	iron ion homeostasis
KF715C_RS09400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KF715C_RS09400	COG0456	acetyltransferase
KF715C_RS09435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS09445	COG5002	protein histidine kinase activity
KF715C_RS09460	COG1953	Uracil, thiamine, allantoin
KF715C_RS09495	COG0789	Transcriptional regulator
KF715C_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS09530	COG0583	DNA-binding transcription factor activity
KF715C_RS09540	COG0174	glutamine synthetase
KF715C_RS09545	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KF715C_RS09610	COG3383	formate dehydrogenase (NAD+) activity
KF715C_RS09620	COG0589	response to stress
KF715C_RS09665	COG0010	Belongs to the arginase family
KF715C_RS09675	COG2133	pyrroloquinoline quinone binding
KF715C_RS09680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KF715C_RS09685	COG0596	Alpha beta hydrolase
KF715C_RS09690	COG1238	metal cluster binding
KF715C_RS09710	COG0826	peptidase U32
KF715C_RS09720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS09725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KF715C_RS09730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KF715C_RS09735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KF715C_RS09740	COG0583	DNA-binding transcription factor activity
KF715C_RS09745	COG2207	Transcriptional regulator
KF715C_RS09755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KF715C_RS09765	COG0183	Belongs to the thiolase family
KF715C_RS09770	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS09775	COG1024	Enoyl-CoA hydratase
KF715C_RS09800	COG1320	monovalent cation:proton antiporter activity
KF715C_RS09805	COG2212	antiporter activity
KF715C_RS09815	COG0651	ATP synthesis coupled electron transport
KF715C_RS09820	COG1006	Multisubunit Na H antiporter MnhC subunit
KF715C_RS09825	COG2111	Na H antiporter
KF715C_RS09825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KF715C_RS09840	COG1335	isochorismatase
KF715C_RS09875	COG5006	permease, DMT superfamily
KF715C_RS09925	COG0183	Belongs to the thiolase family
KF715C_RS09930	COG1024	Enoyl-CoA hydratase
KF715C_RS09930	COG1250	3-hydroxyacyl-CoA dehydrogenase
KF715C_RS09940	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS09945	COG2909	trisaccharide binding
KF715C_RS09970	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS09980	COG2175	clavaminate synthase activity
KF715C_RS09995	COG2855	membrane
KF715C_RS10020	COG4447	cellulose binding
KF715C_RS10030	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS10035	COG3246	L-lysine catabolic process to acetate
KF715C_RS10040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KF715C_RS10070	COG0730	response to heat
KF715C_RS10075	COG0251	oxidation-reduction process
KF715C_RS10080	COG0840	transmembrane signaling receptor activity
KF715C_RS10085	COG0583	DNA-binding transcription factor activity
KF715C_RS10105	COG2186	Transcriptional regulator
KF715C_RS10115	COG0840	transmembrane signaling receptor activity
KF715C_RS10125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KF715C_RS10155	COG0544	peptidyl-prolyl cis-trans isomerase activity
KF715C_RS10160	COG0740	serine-type endopeptidase activity
KF715C_RS10165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KF715C_RS10170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KF715C_RS10180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KF715C_RS10220	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KF715C_RS10230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KF715C_RS10235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KF715C_RS10240	COG4181	ATPase activity
KF715C_RS10255	COG1388	LysM domain
KF715C_RS10255	COG1376	ErfK ybiS ycfS ynhG family protein
KF715C_RS10275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KF715C_RS10280	COG0589	response to stress
KF715C_RS10310	COG0189	ligase activity
KF715C_RS10310	COG4067	protein conserved in archaea
KF715C_RS10315	COG1802	Transcriptional regulator
KF715C_RS10325	COG0372	Belongs to the citrate synthase family
KF715C_RS10340	COG2079	MmgE PrpD family protein
KF715C_RS10355	COG0720	synthase
KF715C_RS10385	COG0517	IMP dehydrogenase activity
KF715C_RS10400	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KF715C_RS10420	COG0745	RESPONSE REGULATOR receiver
KF715C_RS10425	COG4251	negative regulation of phosphorylation
KF715C_RS10465	COG2866	Carboxypeptidase
KF715C_RS10475	COG2365	Tyrosine phosphatase family
KF715C_RS10480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS10485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS10490	COG2207	Transcriptional regulator
KF715C_RS10495	COG2223	nitrite transmembrane transporter activity
KF715C_RS10540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KF715C_RS10545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KF715C_RS10545	COG0316	Belongs to the HesB IscA family
KF715C_RS10550	COG1999	signal sequence binding
KF715C_RS10605	COG0583	DNA-binding transcription factor activity
KF715C_RS10610	COG0583	DNA-binding transcription factor activity
KF715C_RS10615	COG2814	Major facilitator Superfamily
KF715C_RS10620	COG0417	DNA replication proofreading
KF715C_RS10635	COG2205	protein histidine kinase activity
KF715C_RS10660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KF715C_RS10665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KF715C_RS10685	COG0477	Major facilitator Superfamily
KF715C_RS10690	COG4774	siderophore transport
KF715C_RS10700	COG1192	Involved in chromosome partitioning
KF715C_RS10735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KF715C_RS10740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KF715C_RS10755	COG4774	siderophore transport
KF715C_RS10770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KF715C_RS10785	COG2249	NAD(P)H dehydrogenase (quinone) activity
KF715C_RS10795	COG2207	Transcriptional regulator
KF715C_RS10800	COG1064	alcohol dehydrogenase
KF715C_RS10810	COG2814	Major facilitator Superfamily
KF715C_RS10825	COG0583	DNA-binding transcription factor activity
KF715C_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS10845	COG0583	DNA-binding transcription factor activity
KF715C_RS10860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS10875	COG4106	trans-aconitate 2-methyltransferase activity
KF715C_RS10885	COG0583	DNA-binding transcription factor activity
KF715C_RS10895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS10900	COG0217	transcriptional regulatory protein
KF715C_RS10905	COG0583	DNA-binding transcription factor activity
KF715C_RS10910	COG0076	glutamate decarboxylase activity
KF715C_RS10925	COG1082	Xylose isomerase domain protein TIM barrel
KF715C_RS10925	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KF715C_RS10935	COG1116	anion transmembrane transporter activity
KF715C_RS10940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS10945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS10950	COG4206	TonB-dependent receptor
KF715C_RS10955	COG4771	TonB-dependent receptor
KF715C_RS10970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS10975	COG1132	(ABC) transporter
KF715C_RS10980	COG1132	(ABC) transporter
KF715C_RS11000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS11005	COG0747	negative chemotaxis
KF715C_RS11015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KF715C_RS11025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS11040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS11055	COG3829	transcription factor binding
KF715C_RS11070	COG1595	DNA-templated transcription, initiation
KF715C_RS11080	COG4774	siderophore transport
KF715C_RS11095	COG3712	iron ion homeostasis
KF715C_RS11100	COG1595	DNA-templated transcription, initiation
KF715C_RS11115	COG0210	DNA helicase
KF715C_RS11130	COG0596	Alpha beta hydrolase
KF715C_RS11150	COG0477	Major facilitator Superfamily
KF715C_RS11160	COG0346	lactoylglutathione lyase activity
KF715C_RS11190	COG1309	transcriptional regulator
KF715C_RS11195	COG2194	sulfuric ester hydrolase activity
KF715C_RS11240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KF715C_RS11245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KF715C_RS11250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KF715C_RS11265	COG4221	oxidoreductase activity
KF715C_RS11270	COG2233	PERMEase
KF715C_RS11285	COG0583	DNA-binding transcription factor activity
KF715C_RS11305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KF715C_RS11315	COG0583	DNA-binding transcription factor activity
KF715C_RS11320	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS11325	COG0531	amino acid
KF715C_RS11345	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS11350	COG1053	succinate dehydrogenase
KF715C_RS11360	COG0673	inositol 2-dehydrogenase activity
KF715C_RS11485	COG1053	succinate dehydrogenase
KF715C_RS11495	COG1053	succinate dehydrogenase
KF715C_RS11500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KF715C_RS11505	COG1414	Transcriptional regulator
KF715C_RS11510	COG1132	(ABC) transporter
KF715C_RS11515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KF715C_RS11535	COG1595	DNA-templated transcription, initiation
KF715C_RS11605	COG1309	transcriptional regulator
KF715C_RS11645	COG2271	Major facilitator Superfamily
KF715C_RS11675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KF715C_RS11685	COG0581	inorganic phosphate transmembrane transporter activity
KF715C_RS11690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KF715C_RS11715	COG2205	protein histidine kinase activity
KF715C_RS11715	COG0784	Response regulator, receiver
KF715C_RS11735	COG1131	(ABC) transporter
KF715C_RS11815	COG0784	Response regulator, receiver
KF715C_RS11815	COG5002	protein histidine kinase activity
KF715C_RS11815	COG2205	protein histidine kinase activity
KF715C_RS11820	COG0583	DNA-binding transcription factor activity
KF715C_RS11825	COG3048	D-serine ammonia-lyase activity
KF715C_RS11830	COG2610	gluconate transmembrane transporter activity
KF715C_RS11845	COG1305	Transglutaminase-like
KF715C_RS11855	COG2308	Evidence 4 Homologs of previously reported genes of
KF715C_RS11860	COG0251	oxidation-reduction process
KF715C_RS11875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KF715C_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS11900	COG0010	Belongs to the arginase family
KF715C_RS11905	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS11925	COG1113	amino acid transport
KF715C_RS11945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KF715C_RS11950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KF715C_RS11955	COG0678	peroxiredoxin activity
KF715C_RS11960	COG0583	DNA-binding transcription factor activity
KF715C_RS11975	COG1473	amidohydrolase
KF715C_RS11985	COG0708	Exodeoxyribonuclease III
KF715C_RS11990	COG0028	Belongs to the TPP enzyme family
KF715C_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS12010	COG0693	protein deglycase activity
KF715C_RS12015	COG1366	Belongs to the anti-sigma-factor antagonist family
KF715C_RS12020	COG1366	Belongs to the anti-sigma-factor antagonist family
KF715C_RS12025	COG2172	sigma factor antagonist activity
KF715C_RS12040	COG4191	Histidine kinase
KF715C_RS12040	COG0784	Response regulator, receiver
KF715C_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS12060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KF715C_RS12065	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KF715C_RS12070	COG2080	2 iron, 2 sulfur cluster binding
KF715C_RS12090	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KF715C_RS12100	COG0431	NADPH-dependent FMN reductase
KF715C_RS12110	COG0640	Transcriptional regulator
KF715C_RS12120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KF715C_RS12150	COG3220	belongs to the UPF0276 family
KF715C_RS12160	COG1595	DNA-templated transcription, initiation
KF715C_RS12165	COG4944	Protein of unknown function (DUF1109)
KF715C_RS12190	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS12200	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS12250	COG3046	protein related to deoxyribodipyrimidine photolyase
KF715C_RS12265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KF715C_RS12280	COG4221	oxidoreductase activity
KF715C_RS12290	COG1366	Belongs to the anti-sigma-factor antagonist family
KF715C_RS12295	COG0789	Transcriptional regulator
KF715C_RS12300	COG3158	transport of potassium into the cell
KF715C_RS12330	COG2271	Major facilitator Superfamily
KF715C_RS12335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KF715C_RS12340	COG0730	response to heat
KF715C_RS12350	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KF715C_RS12355	COG1501	Belongs to the glycosyl hydrolase 31 family
KF715C_RS12420	COG0604	alcohol dehydrogenase
KF715C_RS12420	COG3321	synthase
KF715C_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS12435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS12445	COG4948	Mandelate Racemase Muconate Lactonizing
KF715C_RS12455	COG0583	DNA-binding transcription factor activity
KF715C_RS12460	COG2721	sulfolactate sulfo-lyase activity
KF715C_RS12485	COG1199	ATP-dependent helicase activity
KF715C_RS12485	COG1199	ATP-dependent helicase activity
KF715C_RS12490	COG4974	Belongs to the 'phage' integrase family
KF715C_RS12495	COG0829	nickel cation binding
KF715C_RS12500	COG0831	urea catabolic process
KF715C_RS12505	COG0832	Belongs to the urease beta subunit family
KF715C_RS12510	COG0804	urea catabolic process
KF715C_RS12515	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KF715C_RS12525	COG0830	nickel cation binding
KF715C_RS12530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KF715C_RS12585	COG0840	transmembrane signaling receptor activity
KF715C_RS12590	COG1968	undecaprenyl-diphosphatase activity
KF715C_RS12605	COG0583	DNA-binding transcription factor activity
KF715C_RS12610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KF715C_RS12620	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS12620	COG0446	pyridine nucleotide-disulphide oxidoreductase
KF715C_RS12630	COG0235	Class ii aldolase
KF715C_RS12640	COG0393	Putative heavy-metal-binding
KF715C_RS12680	COG4221	oxidoreductase activity
KF715C_RS12695	COG1917	Cupin 2, conserved barrel domain protein
KF715C_RS12695	COG1396	sequence-specific DNA binding
KF715C_RS12700	COG0477	Major facilitator Superfamily
KF715C_RS12705	COG3038	cytochrome b561
KF715C_RS12715	COG1595	DNA-templated transcription, initiation
KF715C_RS12725	COG0708	Exodeoxyribonuclease III
KF715C_RS12735	COG0729	surface antigen
KF715C_RS12775	COG2366	antibiotic biosynthetic process
KF715C_RS12780	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KF715C_RS12790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KF715C_RS12795	COG0215	cysteine-tRNA ligase activity
KF715C_RS12810	COG3850	Histidine kinase
KF715C_RS12810	COG5002	protein histidine kinase activity
KF715C_RS12815	COG0745	RESPONSE REGULATOR receiver
KF715C_RS12820	COG1802	Transcriptional regulator
KF715C_RS12830	COG0579	oxidoreductase
KF715C_RS12835	COG1113	amino acid transport
KF715C_RS12845	COG0113	porphobilinogen synthase activity
KF715C_RS12860	COG0307	riboflavin synthase, alpha
KF715C_RS12875	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KF715C_RS12885	COG1984	allophanate hydrolase subunit 2
KF715C_RS12930	COG0579	oxidoreductase
KF715C_RS12935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KF715C_RS12945	COG0463	Glycosyl transferase, family 2
KF715C_RS12970	COG0019	diaminopimelate decarboxylase activity
KF715C_RS12990	COG0625	glutathione transferase activity
KF715C_RS13005	COG0488	(ABC) transporter
KF715C_RS13115	COG1253	flavin adenine dinucleotide binding
KF715C_RS13125	COG2200	EAL domain
KF715C_RS13145	COG4191	Histidine kinase
KF715C_RS13145	COG0784	Response regulator, receiver
KF715C_RS13170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS13180	COG3712	iron ion homeostasis
KF715C_RS13185	COG1595	DNA-templated transcription, initiation
KF715C_RS13205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS13210	COG1459	type II secretion system
KF715C_RS13220	COG1196	nuclear chromosome segregation
KF715C_RS13220	COG0741	lytic transglycosylase activity
KF715C_RS13220	COG0739	heme binding
KF715C_RS13225	COG5002	protein histidine kinase activity
KF715C_RS13235	COG2205	protein histidine kinase activity
KF715C_RS13240	COG2204	response regulator
KF715C_RS13255	COG3265	gluconokinase activity
KF715C_RS13260	COG1609	Transcriptional regulator
KF715C_RS13270	COG2205	protein histidine kinase activity
KF715C_RS13270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS13275	COG2197	response regulator
KF715C_RS13280	COG3813	Protein conserved in bacteria
KF715C_RS13310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS13315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS13325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KF715C_RS13330	COG0601	transmembrane transport
KF715C_RS13335	COG0747	negative chemotaxis
KF715C_RS13340	COG0235	Class ii aldolase
KF715C_RS13350	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13355	COG0583	DNA-binding transcription factor activity
KF715C_RS13360	COG1609	Transcriptional regulator
KF715C_RS13365	COG4771	TonB-dependent receptor
KF715C_RS13370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS13375	COG0667	Aldo Keto reductase
KF715C_RS13380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS13450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KF715C_RS13455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KF715C_RS13465	COG2271	Major facilitator Superfamily
KF715C_RS13535	COG1609	Transcriptional regulator
KF715C_RS13545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KF715C_RS13550	COG2271	Major facilitator Superfamily
KF715C_RS13560	COG2356	endonuclease I
KF715C_RS13570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KF715C_RS13575	COG0745	RESPONSE REGULATOR receiver
KF715C_RS13580	COG2205	protein histidine kinase activity
KF715C_RS13585	COG0667	Aldo Keto reductase
KF715C_RS13595	COG2814	Major facilitator Superfamily
KF715C_RS13600	COG1522	sequence-specific DNA binding
KF715C_RS13605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS13610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS13615	COG1126	abc transporter atp-binding protein
KF715C_RS13620	COG0765	amino acid transport
KF715C_RS13665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KF715C_RS13680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KF715C_RS13695	COG0765	amino acid transport
KF715C_RS13700	COG0765	amino acid transport
KF715C_RS13705	COG1126	abc transporter atp-binding protein
KF715C_RS13720	COG2814	Major facilitator Superfamily
KF715C_RS13725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KF715C_RS13730	COG4569	acetaldehyde dehydrogenase (acetylating) activity
KF715C_RS13745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KF715C_RS13750	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS13785	COG1024	Enoyl-CoA hydratase
KF715C_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS13800	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13815	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13820	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13825	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13840	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS13840	COG0446	pyridine nucleotide-disulphide oxidoreductase
KF715C_RS13850	COG2814	Major facilitator Superfamily
KF715C_RS13870	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS13875	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS13915	COG1024	Enoyl-CoA hydratase
KF715C_RS13925	COG1024	Enoyl-CoA hydratase
KF715C_RS13930	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13935	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS13940	COG0183	Belongs to the thiolase family
KF715C_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS13960	COG0183	Belongs to the thiolase family
KF715C_RS13985	COG0300	oxidoreductase activity
KF715C_RS14000	COG0784	Response regulator, receiver
KF715C_RS14000	COG4191	Histidine kinase
KF715C_RS14025	COG2721	sulfolactate sulfo-lyase activity
KF715C_RS14030	COG2271	Major facilitator Superfamily
KF715C_RS14050	COG0477	Major facilitator Superfamily
KF715C_RS14065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KF715C_RS14080	COG0346	lactoylglutathione lyase activity
KF715C_RS14095	COG1846	Transcriptional regulator
KF715C_RS14100	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KF715C_RS14140	COG0668	transmembrane transport
KF715C_RS14145	COG3327	negative regulation of DNA-templated transcription, initiation
KF715C_RS14155	COG1024	Enoyl-CoA hydratase
KF715C_RS14160	COG1024	Enoyl-CoA hydratase
KF715C_RS14165	COG1250	3-hydroxyacyl-CoA dehydrogenase
KF715C_RS14170	COG2050	protein possibly involved in aromatic compounds catabolism
KF715C_RS14175	COG0183	Belongs to the thiolase family
KF715C_RS14185	COG3396	Phenylacetate-CoA oxygenase
KF715C_RS14190	COG3460	Phenylacetate-CoA oxygenase
KF715C_RS14195	COG3396	Phenylacetate-CoA oxygenase
KF715C_RS14200	COG2151	metal-sulfur cluster biosynthetic enzyme
KF715C_RS14205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KF715C_RS14210	COG3162	membrane
KF715C_RS14225	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS14225	COG2030	dehydratase
KF715C_RS14235	COG1063	alcohol dehydrogenase
KF715C_RS14245	COG0494	nUDIX hydrolase
KF715C_RS14260	COG3568	Endonuclease Exonuclease Phosphatase
KF715C_RS14270	COG0392	lysyltransferase activity
KF715C_RS14295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KF715C_RS14315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KF715C_RS14320	COG2890	protein-(glutamine-N5) methyltransferase activity
KF715C_RS14345	COG0667	Aldo Keto reductase
KF715C_RS14350	COG2837	iron assimilation
KF715C_RS14405	COG3384	dioxygenase
KF715C_RS14425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KF715C_RS14430	COG2423	ornithine cyclodeaminase activity
KF715C_RS14435	COG0402	S-adenosylhomocysteine deaminase activity
KF715C_RS14445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KF715C_RS14450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KF715C_RS14465	COG1999	signal sequence binding
KF715C_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS14485	COG0583	DNA-binding transcription factor activity
KF715C_RS14490	COG1929	Belongs to the glycerate kinase type-1 family
KF715C_RS14495	COG3835	regulator
KF715C_RS14500	COG2271	Major facilitator Superfamily
KF715C_RS14505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KF715C_RS14510	COG0667	Aldo Keto reductase
KF715C_RS14515	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS14520	COG1278	Cold shock
KF715C_RS14545	COG3135	benzoate transporter
KF715C_RS14550	COG3485	protocatechuate 3,4-dioxygenase
KF715C_RS14555	COG2814	Major facilitator Superfamily
KF715C_RS14625	COG0583	DNA-binding transcription factor activity
KF715C_RS14630	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS14645	COG0174	glutamine synthetase
KF715C_RS14655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS14665	COG1760	l-serine dehydratase
KF715C_RS14670	COG0583	DNA-binding transcription factor activity
KF715C_RS14675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KF715C_RS14690	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS14695	COG2990	Protein conserved in bacteria
KF715C_RS14700	COG1215	transferase activity, transferring glycosyl groups
KF715C_RS14745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KF715C_RS14770	COG1396	sequence-specific DNA binding
KF715C_RS14775	COG2031	fatty acid transporter
KF715C_RS14785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KF715C_RS14795	COG0656	L-ascorbic acid biosynthetic process
KF715C_RS14805	COG0587	DNA-directed DNA polymerase activity
KF715C_RS14820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KF715C_RS14845	COG1053	succinate dehydrogenase
KF715C_RS14850	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS14860	COG1414	Transcriptional regulator
KF715C_RS14865	COG0154	amidase activity
KF715C_RS14875	COG1473	amidohydrolase
KF715C_RS14915	COG1881	PFAM PEBP family protein
KF715C_RS14920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KF715C_RS14925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KF715C_RS14935	COG4174	ABC transporter (Permease)
KF715C_RS14940	COG4239	(ABC) transporter, permease
KF715C_RS14945	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS14950	COG4574	serine-type endopeptidase inhibitor activity
KF715C_RS14955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KF715C_RS14980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KF715C_RS14995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KF715C_RS15005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KF715C_RS15015	COG1215	transferase activity, transferring glycosyl groups
KF715C_RS15030	COG3706	GGDEF domain
KF715C_RS15035	COG2205	protein histidine kinase activity
KF715C_RS15040	COG0745	RESPONSE REGULATOR receiver
KF715C_RS15045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS15060	COG0746	molybdenum cofactor guanylyltransferase activity
KF715C_RS15065	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS15090	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS15110	COG1132	(ABC) transporter
KF715C_RS15115	COG3284	Transcriptional regulator
KF715C_RS15150	COG2165	general secretion pathway protein
KF715C_RS15160	COG4796	Type ii and iii secretion system protein
KF715C_RS15185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KF715C_RS15280	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS15295	COG2384	SAM-dependent methyltransferase
KF715C_RS15305	COG0826	peptidase U32
KF715C_RS15310	COG2204	response regulator
KF715C_RS15350	COG0488	(ABC) transporter
KF715C_RS15355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KF715C_RS15365	COG0583	DNA-binding transcription factor activity
KF715C_RS15400	COG1309	transcriptional regulator
KF715C_RS15405	COG0697	spore germination
KF715C_RS15415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS15425	COG3257	ureidoglycine aminohydrolase activity
KF715C_RS15435	COG1113	amino acid transport
KF715C_RS15440	COG1522	sequence-specific DNA binding
KF715C_RS15445	COG2423	ornithine cyclodeaminase activity
KF715C_RS15455	COG0583	DNA-binding transcription factor activity
KF715C_RS15460	COG0405	Gamma-glutamyltransferase
KF715C_RS15475	COG2207	Transcriptional regulator
KF715C_RS15480	COG0789	Transcriptional regulator
KF715C_RS15490	COG1285	pathogenesis
KF715C_RS15500	COG0348	domain, Protein
KF715C_RS15505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS15515	COG0784	Response regulator, receiver
KF715C_RS15515	COG4191	Histidine kinase
KF715C_RS15520	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS15525	COG2814	Major facilitator Superfamily
KF715C_RS15530	COG1566	PFAM secretion protein HlyD family protein
KF715C_RS15535	COG1846	Transcriptional regulator
KF715C_RS15540	COG4566	intracellular signal transduction
KF715C_RS15550	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS15555	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS15565	COG2056	Na+-H+ antiporter family
KF715C_RS15575	COG0840	transmembrane signaling receptor activity
KF715C_RS15585	COG4176	ABC-type proline glycine betaine transport system permease component
KF715C_RS15590	COG0583	DNA-binding transcription factor activity
KF715C_RS15620	COG1280	lysine exporter protein (LysE YggA)
KF715C_RS15625	COG2814	Major facilitator Superfamily
KF715C_RS15630	COG0583	DNA-binding transcription factor activity
KF715C_RS15655	COG2072	flavoprotein involved in K transport
KF715C_RS15670	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS15675	COG2271	Major facilitator Superfamily
KF715C_RS15690	COG4774	siderophore transport
KF715C_RS15695	COG3712	iron ion homeostasis
KF715C_RS15700	COG1595	DNA-templated transcription, initiation
KF715C_RS15750	COG0814	amino acid
KF715C_RS15775	COG4215	(ABC) transporter
KF715C_RS15785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS15790	COG1126	abc transporter atp-binding protein
KF715C_RS15795	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KF715C_RS15800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KF715C_RS15805	COG2271	Major facilitator Superfamily
KF715C_RS15810	COG2721	sulfolactate sulfo-lyase activity
KF715C_RS15815	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS15820	COG2186	Transcriptional regulator
KF715C_RS15835	COG2391	methyltransferase activity
KF715C_RS15850	COG4335	DNA alkylation repair
KF715C_RS15890	COG1944	ATP diphosphatase activity
KF715C_RS15930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KF715C_RS15945	COG4991	sh3 domain protein
KF715C_RS15960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KF715C_RS15970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KF715C_RS15975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KF715C_RS15980	COG1116	anion transmembrane transporter activity
KF715C_RS16025	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KF715C_RS16035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS16045	COG2267	carboxylic ester hydrolase activity
KF715C_RS16050	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS16060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KF715C_RS16065	COG2186	Transcriptional regulator
KF715C_RS16070	COG2816	NAD+ diphosphatase activity
KF715C_RS16075	COG0784	Response regulator, receiver
KF715C_RS16075	COG4191	Histidine kinase
KF715C_RS16090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KF715C_RS16095	COG0069	glutamate synthase activity
KF715C_RS16100	COG2218	PFAM glutamate synthase alpha subunit domain protein
KF715C_RS16105	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KF715C_RS16120	COG3920	Histidine kinase
KF715C_RS16140	COG2855	membrane
KF715C_RS16145	COG1611	Belongs to the LOG family
KF715C_RS16155	COG5001	Diguanylate cyclase
KF715C_RS16155	COG3300	MHYT domain
KF715C_RS16160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KF715C_RS16170	COG0477	Major facilitator Superfamily
KF715C_RS16180	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KF715C_RS16190	COG0656	L-ascorbic acid biosynthetic process
KF715C_RS16195	COG5001	Diguanylate cyclase
KF715C_RS16205	COG3485	protocatechuate 3,4-dioxygenase
KF715C_RS16210	COG4829	muconolactone delta-isomerase
KF715C_RS16215	COG4948	Mandelate Racemase Muconate Lactonizing
KF715C_RS16225	COG1113	amino acid transport
KF715C_RS16235	COG1522	sequence-specific DNA binding
KF715C_RS16240	COG0583	DNA-binding transcription factor activity
KF715C_RS16260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KF715C_RS16280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KF715C_RS16285	COG2249	NAD(P)H dehydrogenase (quinone) activity
KF715C_RS16300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KF715C_RS16310	COG0045	succinate-CoA ligase (ADP-forming) activity
KF715C_RS16315	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS16320	COG1024	Enoyl-CoA hydratase
KF715C_RS16325	COG0833	amino acid
KF715C_RS16350	COG1024	Enoyl-CoA hydratase
KF715C_RS16360	COG0577	efflux transmembrane transporter activity
KF715C_RS16365	COG4181	ATPase activity
KF715C_RS16400	COG0768	penicillin binding
KF715C_RS16420	COG0559	Belongs to the binding-protein-dependent transport system permease family
KF715C_RS16430	COG2186	Transcriptional regulator
KF715C_RS16435	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS16440	COG0028	Belongs to the TPP enzyme family
KF715C_RS16450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KF715C_RS16455	COG0436	Aminotransferase
KF715C_RS16470	COG4221	oxidoreductase activity
KF715C_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS16480	COG1309	transcriptional regulator
KF715C_RS16520	COG2186	Transcriptional regulator
KF715C_RS16525	COG0277	FAD linked oxidase domain protein
KF715C_RS16530	COG0277	FAD linked oxidase domain protein
KF715C_RS16535	COG0247	lactate metabolic process
KF715C_RS16540	COG3193	protein, possibly involved in utilization of glycolate and propanediol
KF715C_RS16545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KF715C_RS16560	COG2807	transmembrane transport
KF715C_RS16565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KF715C_RS16575	COG0183	Belongs to the thiolase family
KF715C_RS16580	COG1250	3-hydroxyacyl-CoA dehydrogenase
KF715C_RS16590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS16590	COG0784	Response regulator, receiver
KF715C_RS16590	COG2205	protein histidine kinase activity
KF715C_RS16590	COG2198	Histidine kinase
KF715C_RS16595	COG2205	protein histidine kinase activity
KF715C_RS16595	COG3437	response regulator, receiver
KF715C_RS16595	COG3850	Histidine kinase
KF715C_RS16595	COG4999	Histidine kinase
KF715C_RS16605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KF715C_RS16610	COG2198	Histidine kinase
KF715C_RS16610	COG2205	protein histidine kinase activity
KF715C_RS16610	COG0784	Response regulator, receiver
KF715C_RS16645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KF715C_RS16700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KF715C_RS16715	COG1686	Belongs to the peptidase S11 family
KF715C_RS16755	COG1121	(ABC) transporter
KF715C_RS16800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KF715C_RS16805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS16815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KF715C_RS16815	COG0446	pyridine nucleotide-disulphide oxidoreductase
KF715C_RS16830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KF715C_RS16840	COG1176	ABC-type spermidine putrescine transport system, permease component I
KF715C_RS16845	COG1177	transmembrane transport
KF715C_RS16850	COG3842	ATPase activity
KF715C_RS16855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KF715C_RS16860	COG0861	Integral membrane protein TerC family
KF715C_RS16880	COG1104	cysteine desulfurase activity
KF715C_RS16885	COG5654	RES domain protein
KF715C_RS16890	COG5642	Protein of unknown function (DUF2384)
KF715C_RS16895	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS16915	COG0625	glutathione transferase activity
KF715C_RS16920	COG2814	Major facilitator Superfamily
KF715C_RS16925	COG0583	DNA-binding transcription factor activity
KF715C_RS16945	COG2814	Major facilitator Superfamily
KF715C_RS16960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KF715C_RS16965	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS16970	COG0183	Belongs to the thiolase family
KF715C_RS16975	COG1022	Amp-dependent synthetase and ligase
KF715C_RS16980	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS16985	COG1024	Enoyl-CoA hydratase
KF715C_RS16995	COG4771	TonB-dependent receptor
KF715C_RS17000	COG1231	oxidoreductase activity
KF715C_RS17020	COG2873	o-acetylhomoserine
KF715C_RS17040	COG0667	Aldo Keto reductase
KF715C_RS17065	COG0583	DNA-binding transcription factor activity
KF715C_RS17070	COG2066	Belongs to the glutaminase family
KF715C_RS17080	COG0697	spore germination
KF715C_RS17085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS17100	COG3384	dioxygenase
KF715C_RS17105	COG0583	DNA-binding transcription factor activity
KF715C_RS17110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KF715C_RS17115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KF715C_RS17120	COG2828	Protein conserved in bacteria
KF715C_RS17130	COG0302	gtp cyclohydrolase
KF715C_RS17140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KF715C_RS17155	COG3344	reverse transcriptase
KF715C_RS17205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KF715C_RS17240	COG3344	reverse transcriptase
KF715C_RS17350	COG3728	DNA packaging
KF715C_RS17350	COG5484	DNA packaging
KF715C_RS17385	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KF715C_RS17590	COG0789	Transcriptional regulator
KF715C_RS17620	COG2814	Major facilitator Superfamily
KF715C_RS17625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KF715C_RS17630	COG1846	Transcriptional regulator
KF715C_RS17650	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS17655	COG3384	dioxygenase
KF715C_RS17665	COG3971	2-oxopent-4-enoate hydratase activity
KF715C_RS17675	COG1846	Transcriptional regulator
KF715C_RS17685	COG3384	dioxygenase
KF715C_RS17700	COG2271	Major facilitator Superfamily
KF715C_RS17705	COG3659	wide pore channel activity
KF715C_RS17715	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS17725	COG2801	Transposase and inactivated derivatives
KF715C_RS17725	COG3415	Transposase
KF715C_RS17805	COG1192	Involved in chromosome partitioning
KF715C_RS17850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KF715C_RS17915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KF715C_RS18125	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS18130	COG1024	Enoyl-CoA hydratase
KF715C_RS18140	COG0702	epimerase
KF715C_RS18165	COG3039	Transposase
KF715C_RS18170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KF715C_RS18175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KF715C_RS18185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KF715C_RS18215	COG0840	transmembrane signaling receptor activity
KF715C_RS18220	COG1846	Transcriptional regulator
KF715C_RS18225	COG0179	Fumarylacetoacetate (FAA) hydrolase
KF715C_RS18235	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS18240	COG3384	dioxygenase
KF715C_RS18250	COG3971	2-oxopent-4-enoate hydratase activity
KF715C_RS18280	COG0776	regulation of translation
KF715C_RS18285	COG0072	phenylalanine-tRNA ligase activity
KF715C_RS18290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KF715C_RS18295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KF715C_RS18300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KF715C_RS18305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KF715C_RS18310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KF715C_RS18320	COG1278	Cold shock
KF715C_RS18340	COG1869	D-ribose catabolic process
KF715C_RS18345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KF715C_RS18350	COG1609	Transcriptional regulator
KF715C_RS18355	COG1172	Belongs to the binding-protein-dependent transport system permease family
KF715C_RS18360	COG1129	ABC transporter
KF715C_RS18370	COG0252	asparaginase activity
KF715C_RS18375	COG4772	TonB-dependent receptor
KF715C_RS18390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KF715C_RS18400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KF715C_RS18405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KF715C_RS18410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KF715C_RS18415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KF715C_RS18505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS18515	COG1253	flavin adenine dinucleotide binding
KF715C_RS18525	COG0583	DNA-binding transcription factor activity
KF715C_RS18530	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KF715C_RS18535	COG3132	Protein of unknown function, DUF480
KF715C_RS18545	COG3634	alkyl hydroperoxide reductase activity
KF715C_RS18560	COG3344	reverse transcriptase
KF715C_RS18570	COG3258	Cytochrome c
KF715C_RS18575	COG2863	cytochrome
KF715C_RS18610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KF715C_RS18620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KF715C_RS18630	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KF715C_RS18635	COG0784	Response regulator, receiver
KF715C_RS18635	COG4191	Histidine kinase
KF715C_RS18650	COG2259	Doxx family
KF715C_RS18660	COG1064	alcohol dehydrogenase
KF715C_RS18670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KF715C_RS18680	COG2135	peptidase activity
KF715C_RS18715	COG0616	signal peptide processing
KF715C_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS18770	COG0490	domain, Protein
KF715C_RS18770	COG0471	metal ion transport
KF715C_RS18775	COG2199	diguanylate cyclase activity
KF715C_RS18805	COG2271	Major facilitator Superfamily
KF715C_RS18810	COG1335	isochorismatase
KF715C_RS18815	COG3473	Maleate cis-trans isomerase
KF715C_RS18820	COG0596	Alpha beta hydrolase
KF715C_RS18825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KF715C_RS18830	COG2309	aminopeptidase activity
KF715C_RS18835	COG1846	Transcriptional regulator
KF715C_RS18840	COG2080	2 iron, 2 sulfur cluster binding
KF715C_RS18845	COG2010	Cytochrome c
KF715C_RS18845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KF715C_RS18850	COG1309	transcriptional regulator
KF715C_RS18875	COG4608	Belongs to the ABC transporter superfamily
KF715C_RS18880	COG0444	Belongs to the ABC transporter superfamily
KF715C_RS18890	COG0747	negative chemotaxis
KF715C_RS18895	COG0601	transmembrane transport
KF715C_RS18900	COG0747	negative chemotaxis
KF715C_RS18905	COG4948	Mandelate Racemase Muconate Lactonizing
KF715C_RS18915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KF715C_RS18940	COG0583	DNA-binding transcription factor activity
KF715C_RS18945	COG0840	transmembrane signaling receptor activity
KF715C_RS18955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KF715C_RS18975	COG0583	DNA-binding transcription factor activity
KF715C_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS18990	COG0477	Major facilitator Superfamily
KF715C_RS19020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KF715C_RS19035	COG3344	reverse transcriptase
KF715C_RS19125	COG0740	serine-type endopeptidase activity
KF715C_RS19130	COG4695	Portal protein
KF715C_RS19220	COG1484	DNA-dependent DNA replication
KF715C_RS19275	COG0629	single-stranded DNA binding
KF715C_RS19285	COG5532	Uncharacterized conserved protein (DUF2303)
KF715C_RS19400	COG1218	3'(2'),5'-bisphosphate nucleotidase
KF715C_RS19455	COG3593	DNA synthesis involved in DNA repair
KF715C_RS19525	COG3685	Protein conserved in bacteria
KF715C_RS19535	COG3546	catalase activity
KF715C_RS19540	COG1063	alcohol dehydrogenase
KF715C_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS19605	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS19610	COG1546	Belongs to the CinA family
KF715C_RS19610	COG1058	Belongs to the CinA family
KF715C_RS19620	COG2323	membrane
KF715C_RS19625	COG3387	PFAM Glycoside hydrolase 15-related
KF715C_RS19650	COG3706	GGDEF domain
KF715C_RS19655	COG3920	Histidine kinase
KF715C_RS19665	COG0861	Integral membrane protein TerC family
KF715C_RS19670	COG0302	gtp cyclohydrolase
KF715C_RS19685	COG3039	Transposase
KF715C_RS19715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KF715C_RS19725	COG0431	NADPH-dependent FMN reductase
KF715C_RS19730	COG0798	PFAM Bile acid sodium symporter
KF715C_RS19735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KF715C_RS19740	COG0640	Transcriptional regulator
KF715C_RS19775	COG3344	reverse transcriptase
KF715C_RS19810	COG2233	PERMEase
KF715C_RS19830	COG2920	part of a sulfur-relay system
KF715C_RS19835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KF715C_RS19840	COG0435	Glutathione S-transferase
KF715C_RS19845	COG1648	precorrin-2 dehydrogenase activity
KF715C_RS19845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KF715C_RS19850	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KF715C_RS19855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KF715C_RS19860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KF715C_RS19865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KF715C_RS19870	COG1674	ftsk spoiiie
KF715C_RS19875	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KF715C_RS19880	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KF715C_RS19885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KF715C_RS19890	COG0542	response to heat
KF715C_RS19895	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KF715C_RS19900	COG1278	Cold shock
KF715C_RS19920	COG0482	sulfurtransferase activity
KF715C_RS19925	COG2915	High frequency lysogenization protein hflD homolog
KF715C_RS19935	COG2850	peptidyl-arginine hydroxylation
KF715C_RS19940	COG2153	protein acetylation
KF715C_RS19950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS19965	COG2816	NAD+ diphosphatase activity
KF715C_RS19970	COG1024	Enoyl-CoA hydratase
KF715C_RS19975	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KF715C_RS19980	COG3040	lipid binding
KF715C_RS19990	COG1234	tRNA 3'-trailer cleavage
KF715C_RS20005	COG1953	Uracil, thiamine, allantoin
KF715C_RS20015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KF715C_RS20030	COG1309	transcriptional regulator
KF715C_RS20040	COG3387	PFAM Glycoside hydrolase 15-related
KF715C_RS20045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KF715C_RS20050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KF715C_RS20060	COG0297	glycogen (starch) synthase activity
KF715C_RS20065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KF715C_RS20070	COG1640	4-alpha-glucanotransferase
KF715C_RS20100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KF715C_RS20105	COG0366	Alpha amylase catalytic
KF715C_RS20115	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS20120	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS20125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KF715C_RS20160	COG0583	DNA-binding transcription factor activity
KF715C_RS20200	COG4372	Transposase
KF715C_RS20235	COG0179	Fumarylacetoacetate (FAA) hydrolase
KF715C_RS20240	COG3971	2-oxopent-4-enoate hydratase activity
KF715C_RS20250	COG0477	Major facilitator Superfamily
KF715C_RS20255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KF715C_RS20265	COG1414	Transcriptional regulator
KF715C_RS20325	COG0629	single-stranded DNA binding
KF715C_RS20330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KF715C_RS20335	COG0270	DNA (cytosine-5-)-methyltransferase activity
KF715C_RS20480	COG1733	regulation of RNA biosynthetic process
KF715C_RS20540	COG2003	Belongs to the UPF0758 family
KF715C_RS20600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KF715C_RS20605	COG3813	Protein conserved in bacteria
KF715C_RS20615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KF715C_RS20620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KF715C_RS20630	COG0456	acetyltransferase
KF715C_RS20630	COG1214	PFAM Peptidase M22, glycoprotease
KF715C_RS20670	COG3135	benzoate transporter
KF715C_RS20680	COG0505	Belongs to the CarA family
KF715C_RS20685	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KF715C_RS20690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KF715C_RS20695	COG0133	tryptophan synthase activity
KF715C_RS20700	COG0159	tryptophan synthase activity
KF715C_RS20705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KF715C_RS20710	COG0583	DNA-binding transcription factor activity
KF715C_RS20715	COG1396	sequence-specific DNA binding
KF715C_RS20725	COG0582	viral genome integration into host DNA
KF715C_RS20740	COG0322	excinuclease ABC activity
KF715C_RS20760	COG3189	MarR family transcriptional regulator
KF715C_RS20765	COG0306	phosphate transporter
KF715C_RS20770	COG0625	glutathione transferase activity
KF715C_RS20775	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KF715C_RS20775	COG2050	protein possibly involved in aromatic compounds catabolism
KF715C_RS20780	COG1113	amino acid transport
KF715C_RS20785	COG0583	DNA-binding transcription factor activity
KF715C_RS20790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KF715C_RS20805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KF715C_RS20810	COG0659	secondary active sulfate transmembrane transporter activity
KF715C_RS20845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KF715C_RS20850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KF715C_RS20855	COG0649	NAD binding
KF715C_RS20855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KF715C_RS20870	COG1034	ATP synthesis coupled electron transport
KF715C_RS20875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KF715C_RS20880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KF715C_RS20890	COG0713	ATP synthesis coupled electron transport
KF715C_RS20905	COG1007	ATP synthesis coupled electron transport
KF715C_RS20940	COG0431	NADPH-dependent FMN reductase
KF715C_RS20960	COG0328	RNA-DNA hybrid ribonuclease activity
KF715C_RS20970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KF715C_RS20975	COG0741	lytic transglycosylase activity
KF715C_RS20975	COG1388	LysM domain
KF715C_RS20985	COG4166	transmembrane transport
KF715C_RS20990	COG4166	transmembrane transport
KF715C_RS20995	COG4174	ABC transporter (Permease)
KF715C_RS21000	COG4239	(ABC) transporter, permease
KF715C_RS21005	COG4172	Belongs to the ABC transporter superfamily
KF715C_RS21015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KF715C_RS21025	COG0583	DNA-binding transcription factor activity
KF715C_RS21030	COG0745	RESPONSE REGULATOR receiver
KF715C_RS21035	COG2205	protein histidine kinase activity
KF715C_RS21040	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KF715C_RS21050	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KF715C_RS21060	COG0628	permease
KF715C_RS21095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KF715C_RS21110	COG2205	protein histidine kinase activity
KF715C_RS21110	COG3437	response regulator, receiver
KF715C_RS21110	COG3850	Histidine kinase
KF715C_RS21110	COG4999	Histidine kinase
KF715C_RS21115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KF715C_RS21130	COG1741	Belongs to the pirin family
KF715C_RS21140	COG0326	Molecular chaperone. Has ATPase activity
KF715C_RS21175	COG0045	succinate-CoA ligase (ADP-forming) activity
KF715C_RS21180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KF715C_RS21200	COG1053	succinate dehydrogenase
KF715C_RS21205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KF715C_RS21210	COG2009	succinate dehydrogenase
KF715C_RS21235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS21240	COG3047	cAMP biosynthetic process
KF715C_RS21240	COG2885	chlorophyll binding
KF715C_RS21270	COG2944	sequence-specific DNA binding
KF715C_RS21300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS21305	COG0577	efflux transmembrane transporter activity
KF715C_RS21305	COG1136	(ABC) transporter
KF715C_RS21310	COG1538	Outer membrane efflux protein
KF715C_RS21330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KF715C_RS21350	COG0657	acetylesterase activity
KF715C_RS21385	COG0642	Histidine kinase
KF715C_RS21405	COG2010	Cytochrome c
KF715C_RS21425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KF715C_RS21440	COG1131	(ABC) transporter
KF715C_RS21470	COG3123	guanosine phosphorylase activity
KF715C_RS21480	COG3278	Belongs to the heme-copper respiratory oxidase family
KF715C_RS21495	COG2010	Cytochrome c
KF715C_RS21505	COG3278	Belongs to the heme-copper respiratory oxidase family
KF715C_RS21520	COG2010	Cytochrome c
KF715C_RS21525	COG0348	domain, Protein
KF715C_RS21535	COG2217	Heavy metal translocating P-type atpase
KF715C_RS21555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KF715C_RS21560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KF715C_RS21565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KF715C_RS21570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KF715C_RS21575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KF715C_RS21600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KF715C_RS21605	COG3115	cell septum assembly
KF715C_RS21635	COG0402	S-adenosylhomocysteine deaminase activity
KF715C_RS21640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KF715C_RS21650	COG2252	PERMEase
KF715C_RS21660	COG3344	reverse transcriptase
KF715C_RS21680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KF715C_RS21690	COG2233	PERMEase
KF715C_RS21705	COG1368	sulfuric ester hydrolase activity
KF715C_RS21710	COG2354	Protein conserved in bacteria
KF715C_RS21725	COG3960	tartronate-semialdehyde synthase activity
KF715C_RS21730	COG3622	Belongs to the hyi family
KF715C_RS21735	COG2084	Dehydrogenase
KF715C_RS21745	COG0469	pyruvate kinase activity
KF715C_RS21760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KF715C_RS21770	COG0668	transmembrane transport
KF715C_RS21775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KF715C_RS21775	COG0116	Belongs to the methyltransferase superfamily
KF715C_RS21785	COG1522	sequence-specific DNA binding
KF715C_RS21790	COG1953	Uracil, thiamine, allantoin
KF715C_RS21825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KF715C_RS21855	COG1138	Cytochrome C-type biogenesis protein
KF715C_RS21860	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KF715C_RS21880	COG4133	protoheme IX ABC transporter activity
KF715C_RS21890	COG2257	FlhB HrpN YscU SpaS Family
KF715C_RS21910	COG0835	chemotaxis
KF715C_RS21920	COG1192	Involved in chromosome partitioning
KF715C_RS21925	COG1360	Flagellar Motor Protein
KF715C_RS21930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KF715C_RS21935	COG2201	protein-glutamate methylesterase activity
KF715C_RS21940	COG0643	Histidine kinase
KF715C_RS21940	COG0784	Response regulator, receiver
KF715C_RS21940	COG2198	Histidine kinase
KF715C_RS21945	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KF715C_RS21970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KF715C_RS21985	COG1987	bacterial-type flagellum assembly
KF715C_RS22025	COG0745	RESPONSE REGULATOR receiver
KF715C_RS22060	COG1677	Flagellar hook-basal body complex protein FliE
KF715C_RS22075	COG1216	Glycosyl transferase, family 2
KF715C_RS22080	COG1215	transferase activity, transferring glycosyl groups
KF715C_RS22115	COG0028	Belongs to the TPP enzyme family
KF715C_RS22135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KF715C_RS22155	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KF715C_RS22160	COG1334	flagellar protein FlaG
KF715C_RS22170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KF715C_RS22180	COG4786	Flagellar basal body rod
KF715C_RS22180	COG1256	bacterial-type flagellum assembly
KF715C_RS22190	COG1706	bacterial-type flagellum-dependent cell motility
KF715C_RS22195	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KF715C_RS22205	COG4787	bacterial-type flagellum-dependent cell motility
KF715C_RS22220	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KF715C_RS22230	COG1815	bacterial-type flagellum-dependent cell motility
KF715C_RS22235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KF715C_RS22240	COG0784	Response regulator, receiver
KF715C_RS22240	COG0835	chemotaxis
KF715C_RS22260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KF715C_RS22265	COG0477	Major facilitator Superfamily
KF715C_RS22275	COG1522	sequence-specific DNA binding
KF715C_RS22280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KF715C_RS22285	COG0022	dehydrogenase e1 component
KF715C_RS22295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KF715C_RS22300	COG3706	GGDEF domain
KF715C_RS22305	COG1802	Transcriptional regulator
KF715C_RS22315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KF715C_RS22320	COG1113	amino acid transport
KF715C_RS22330	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KF715C_RS22345	COG2239	Acts as a magnesium transporter
KF715C_RS22370	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KF715C_RS22375	COG0527	aspartate kinase activity
KF715C_RS22380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KF715C_RS22385	COG2988	succinylglutamate desuccinylase activity
KF715C_RS22395	COG3724	N-succinylarginine dihydrolase activity
KF715C_RS22400	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS22415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KF715C_RS22440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS22445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KF715C_RS22470	COG2154	pterin-4-alpha-carbinolamine dehydratase
KF715C_RS22480	COG0247	lactate metabolic process
KF715C_RS22480	COG0277	FAD linked oxidase domain protein
KF715C_RS22490	COG1113	amino acid transport
KF715C_RS22500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KF715C_RS22510	COG0009	L-threonylcarbamoyladenylate synthase
KF715C_RS22515	COG0613	PHP domain protein
KF715C_RS22520	COG2917	probably involved in intracellular septation
KF715C_RS22525	COG2350	Protein conserved in bacteria
KF715C_RS22530	COG0745	RESPONSE REGULATOR receiver
KF715C_RS22545	COG0778	Nitroreductase
KF715C_RS22550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KF715C_RS22570	COG2207	Transcriptional regulator
KF715C_RS22585	COG1752	Esterase of the alpha-beta hydrolase superfamily
KF715C_RS22595	COG0514	ATP-dependent DNA helicase (RecQ)
KF715C_RS22610	COG2832	Protein of unknown function (DUF454)
KF715C_RS22625	COG0840	transmembrane signaling receptor activity
KF715C_RS22645	COG0583	DNA-binding transcription factor activity
KF715C_RS22655	COG0697	spore germination
KF715C_RS22665	COG3657	addiction module killer protein
KF715C_RS22670	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KF715C_RS22680	COG0513	Belongs to the DEAD box helicase family
KF715C_RS22685	COG0668	transmembrane transport
KF715C_RS22690	COG0679	Auxin Efflux Carrier
KF715C_RS22700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KF715C_RS22715	COG2267	carboxylic ester hydrolase activity
KF715C_RS22725	COG1132	(ABC) transporter
KF715C_RS22735	COG2188	Transcriptional regulator
KF715C_RS22745	COG1643	Atp-dependent helicase
KF715C_RS22755	COG0174	glutamine synthetase
KF715C_RS22760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS22765	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS22770	COG0318	PFAM AMP-dependent synthetase and ligase
KF715C_RS22775	COG2267	carboxylic ester hydrolase activity
KF715C_RS22780	COG2030	dehydratase
KF715C_RS22785	COG4941	Belongs to the sigma-70 factor family
KF715C_RS22795	COG3795	YCII-related domain
KF715C_RS22815	COG0242	peptide deformylase activity
KF715C_RS22820	COG1295	ribonuclease BN
KF715C_RS22830	COG3420	alginic acid biosynthetic process
KF715C_RS22850	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KF715C_RS22880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KF715C_RS22905	COG1984	allophanate hydrolase subunit 2
KF715C_RS22910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KF715C_RS22915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KF715C_RS22920	COG2814	Major facilitator Superfamily
KF715C_RS22935	COG0121	glutamine amidotransferase
KF715C_RS22955	COG0583	DNA-binding transcription factor activity
KF715C_RS22965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KF715C_RS23000	COG0625	glutathione transferase activity
KF715C_RS23015	COG3344	reverse transcriptase
KF715C_RS23020	COG2233	PERMEase
KF715C_RS23025	COG2186	Transcriptional regulator
KF715C_RS23040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KF715C_RS23055	COG0582	viral genome integration into host DNA
KF715C_RS23090	COG2983	Belongs to the UPF0260 family
KF715C_RS23105	COG3100	YcgL domain-containing protein
KF715C_RS23125	COG0626	cystathionine gamma-synthase activity
KF715C_RS23130	COG1522	sequence-specific DNA binding
KF715C_RS23140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KF715C_RS23145	COG3781	membrane
KF715C_RS23155	COG0521	Mo-molybdopterin cofactor biosynthetic process
KF715C_RS23160	COG0583	DNA-binding transcription factor activity
KF715C_RS23170	COG0531	amino acid
KF715C_RS23175	COG3938	Belongs to the proline racemase family
KF715C_RS23180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KF715C_RS23195	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS23200	COG0640	Transcriptional regulator
KF715C_RS23205	COG0579	oxidoreductase
KF715C_RS23210	COG1595	DNA-templated transcription, initiation
KF715C_RS23320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KF715C_RS23325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KF715C_RS23330	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KF715C_RS23335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KF715C_RS23345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KF715C_RS23355	COG0425	Belongs to the sulfur carrier protein TusA family
KF715C_RS23370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KF715C_RS23380	COG0531	amino acid
KF715C_RS23385	COG0840	transmembrane signaling receptor activity
KF715C_RS23400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KF715C_RS23405	COG0602	queuosine metabolic process
KF715C_RS23410	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KF715C_RS23415	COG2885	chlorophyll binding
KF715C_RS23420	COG0823	Involved in the tonB-independent uptake of proteins
KF715C_RS23440	COG0824	Thioesterase
KF715C_RS23445	COG2255	four-way junction helicase activity
KF715C_RS23450	COG0632	four-way junction helicase activity
KF715C_RS23455	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KF715C_RS23460	COG0217	transcriptional regulatory protein
KF715C_RS23465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KF715C_RS23480	COG0783	Belongs to the Dps family
KF715C_RS23490	COG2900	Belongs to the SlyX family
KF715C_RS23505	COG0442	prolyl-tRNA aminoacylation
KF715C_RS23515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KF715C_RS23545	COG3158	transport of potassium into the cell
KF715C_RS23550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KF715C_RS23575	COG0519	Catalyzes the synthesis of GMP from XMP
KF715C_RS23585	COG4807	Protein conserved in bacteria
KF715C_RS23595	COG1301	dicarboxylic acid transport
KF715C_RS23625	COG2205	protein histidine kinase activity
KF715C_RS23630	COG0745	RESPONSE REGULATOR receiver
KF715C_RS23635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KF715C_RS23635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KF715C_RS23640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KF715C_RS23660	COG3077	Addiction module antitoxin, RelB DinJ family
KF715C_RS23670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KF715C_RS23680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KF715C_RS23705	COG2271	Major facilitator Superfamily
KF715C_RS23710	COG0583	DNA-binding transcription factor activity
KF715C_RS23715	COG1017	nitric oxide dioxygenase activity
KF715C_RS23715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KF715C_RS23720	COG0625	glutathione transferase activity
KF715C_RS23725	COG3318	Belongs to the UPF0149 family
KF715C_RS23725	COG3012	SEC-C Motif Domain Protein
KF715C_RS23730	COG0252	asparaginase activity
KF715C_RS23740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KF715C_RS23780	COG2116	formate transmembrane transporter activity
KF715C_RS23785	COG3706	GGDEF domain
KF715C_RS23790	COG5001	Diguanylate cyclase
KF715C_RS23800	COG0583	DNA-binding transcription factor activity
KF715C_RS23805	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS23825	COG1289	transmembrane transporter activity
KF715C_RS23845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KF715C_RS23855	COG2084	Dehydrogenase
KF715C_RS23900	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KF715C_RS23905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KF715C_RS23920	COG0259	pyridoxamine-phosphate oxidase activity
KF715C_RS23925	COG2885	chlorophyll binding
KF715C_RS23940	COG1199	ATP-dependent helicase activity
KF715C_RS23975	COG3012	SEC-C Motif Domain Protein
KF715C_RS23985	COG0653	protein targeting
KF715C_RS23995	COG2814	Major facilitator Superfamily
KF715C_RS24000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KF715C_RS24020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS24025	COG2366	antibiotic biosynthetic process
KF715C_RS24030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KF715C_RS24030	COG1793	dna ligase
KF715C_RS24035	COG1793	dna ligase
KF715C_RS24045	COG1201	RNA secondary structure unwinding
KF715C_RS24060	COG0717	Belongs to the dCTP deaminase family
KF715C_RS24065	COG1278	Cold shock
KF715C_RS24070	COG0489	protein tyrosine kinase activity
KF715C_RS24075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KF715C_RS24075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KF715C_RS24090	COG4659	FMN binding
KF715C_RS24100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KF715C_RS24110	COG2197	response regulator
KF715C_RS24120	COG0137	argininosuccinate synthase activity
KF715C_RS24130	COG0418	dihydroorotase activity
KF715C_RS24135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KF715C_RS24140	COG0450	alkyl hydroperoxide reductase
KF715C_RS24155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KF715C_RS24160	COG0243	molybdopterin cofactor binding
KF715C_RS24165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KF715C_RS24170	COG3842	ATPase activity
KF715C_RS24175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KF715C_RS24185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KF715C_RS24210	COG0765	amino acid transport
KF715C_RS24215	COG0765	amino acid transport
KF715C_RS24220	COG1126	abc transporter atp-binding protein
KF715C_RS24240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KF715C_RS24245	COG0583	DNA-binding transcription factor activity
KF715C_RS24255	COG1201	RNA secondary structure unwinding
KF715C_RS24260	COG0069	glutamate synthase activity
KF715C_RS24265	COG1113	amino acid transport
KF715C_RS24275	COG1695	Transcriptional regulator
KF715C_RS24280	COG2375	cellular response to nickel ion
KF715C_RS24290	COG4628	conserved protein (DUF2132)
KF715C_RS24295	COG4206	TonB-dependent receptor
KF715C_RS24310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KF715C_RS24330	COG2226	methyltransferase
KF715C_RS24335	COG0500	methyltransferase
KF715C_RS24355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KF715C_RS24360	COG1381	Involved in DNA repair and RecF pathway recombination
KF715C_RS24365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KF715C_RS24370	COG0571	ribonuclease III activity
KF715C_RS24375	COG0681	Belongs to the peptidase S26 family
KF715C_RS24380	COG0481	GTPase activity
KF715C_RS24385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KF715C_RS24415	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KF715C_RS24420	COG0354	folic acid binding
KF715C_RS24460	COG3180	Ammonia monooxygenase
KF715C_RS24465	COG0737	Belongs to the 5'-nucleotidase family
KF715C_RS24470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KF715C_RS24500	COG2267	carboxylic ester hydrolase activity
KF715C_RS24545	COG4191	Histidine kinase
KF715C_RS24555	COG0477	Major facilitator Superfamily
KF715C_RS24585	COG2207	Transcriptional regulator
KF715C_RS24595	COG0583	DNA-binding transcription factor activity
KF715C_RS24600	COG2910	NAD(P)H-binding
KF715C_RS24615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KF715C_RS24620	COG0477	Major facilitator Superfamily
KF715C_RS24625	COG1309	transcriptional regulator
KF715C_RS24630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS24635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS24660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KF715C_RS24665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KF715C_RS24670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KF715C_RS24675	COG0477	Major facilitator Superfamily
KF715C_RS24680	COG0183	Belongs to the thiolase family
KF715C_RS24685	COG2814	Major facilitator Superfamily
KF715C_RS24690	COG1414	Transcriptional regulator
KF715C_RS24705	COG0306	phosphate transporter
KF715C_RS24710	COG0433	COG0433 Predicted ATPase
KF715C_RS24715	COG0840	transmembrane signaling receptor activity
KF715C_RS24720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KF715C_RS24720	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS24740	COG0788	formyltetrahydrofolate deformylase activity
KF715C_RS24750	COG2925	Exonuclease
KF715C_RS24765	COG0469	pyruvate kinase activity
KF715C_RS24795	COG0693	protein deglycase activity
KF715C_RS24845	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS24860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KF715C_RS24865	COG0583	DNA-binding transcription factor activity
KF715C_RS24875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KF715C_RS24915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS24920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS24925	COG2814	Major facilitator Superfamily
KF715C_RS24935	COG3642	lipopolysaccharide core region biosynthetic process
KF715C_RS24945	COG0642	Histidine kinase
KF715C_RS24960	COG0459	protein refolding
KF715C_RS24965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KF715C_RS25000	COG0668	transmembrane transport
KF715C_RS25005	COG1666	GTP binding
KF715C_RS25020	COG2096	Adenosyltransferase
KF715C_RS25025	COG0352	thiamine-phosphate diphosphorylase activity
KF715C_RS25035	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KF715C_RS25040	COG0653	protein targeting
KF715C_RS25060	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KF715C_RS25065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KF715C_RS25080	COG1181	Belongs to the D-alanine--D-alanine ligase family
KF715C_RS25085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KF715C_RS25090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KF715C_RS25095	COG0772	Belongs to the SEDS family
KF715C_RS25100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KF715C_RS25105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KF715C_RS25110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KF715C_RS25115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KF715C_RS25130	COG0275	rRNA processing
KF715C_RS25135	COG2001	Belongs to the MraZ family
KF715C_RS25150	COG3107	peptidoglycan biosynthetic process
KF715C_RS25155	COG0792	nuclease activity
KF715C_RS25160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KF715C_RS25165	COG2823	Periplasmic or secreted lipoprotein
KF715C_RS25175	COG2969	positive regulation of protein catabolic process
KF715C_RS25180	COG0625	glutathione transferase activity
KF715C_RS25185	COG2857	Cytochrome c1
KF715C_RS25190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KF715C_RS25195	COG0723	plastoquinol--plastocyanin reductase activity
KF715C_RS25200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KF715C_RS25205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KF715C_RS25210	COG0667	Aldo Keto reductase
KF715C_RS25220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KF715C_RS25225	COG0180	Tryptophanyl-tRNA synthetase
KF715C_RS25245	COG1522	sequence-specific DNA binding
KF715C_RS25270	COG0175	sulfate reduction
KF715C_RS25280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KF715C_RS25285	COG1126	abc transporter atp-binding protein
KF715C_RS25290	COG0765	amino acid transport
KF715C_RS25295	COG4597	amino acid ABC transporter
KF715C_RS25300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS25305	COG0400	carboxylic ester hydrolase activity
KF715C_RS25310	COG0513	Belongs to the DEAD box helicase family
KF715C_RS25320	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KF715C_RS25325	COG0315	cyclic pyranopterin monophosphate synthase activity
KF715C_RS25330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KF715C_RS25340	COG3022	response to hydroperoxide
KF715C_RS25350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KF715C_RS25355	COG1215	transferase activity, transferring glycosyl groups
KF715C_RS25360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS25365	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KF715C_RS25375	COG3420	alginic acid biosynthetic process
KF715C_RS25390	COG1696	Membrane protein involved in D-alanine export
KF715C_RS25405	COG0662	Cupin 2, conserved barrel domain protein
KF715C_RS25405	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KF715C_RS25415	COG0300	oxidoreductase activity
KF715C_RS25445	COG1566	PFAM secretion protein HlyD family protein
KF715C_RS25465	COG0583	DNA-binding transcription factor activity
KF715C_RS25470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KF715C_RS25475	COG0697	spore germination
KF715C_RS25480	COG2207	Transcriptional regulator
KF715C_RS25480	COG3708	Transcriptional regulator
KF715C_RS25485	COG4774	siderophore transport
KF715C_RS25540	COG4964	Belongs to the GSP D family
KF715C_RS25630	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KF715C_RS25640	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS25645	COG0596	Alpha beta hydrolase
KF715C_RS25650	COG1346	cytolysis
KF715C_RS25655	COG1380	Effector of murein hydrolase LrgA
KF715C_RS25660	COG0583	DNA-binding transcription factor activity
KF715C_RS25670	COG1366	Belongs to the anti-sigma-factor antagonist family
KF715C_RS25680	COG0789	Transcriptional regulator
KF715C_RS25710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KF715C_RS25735	COG2957	Belongs to the agmatine deiminase family
KF715C_RS25755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KF715C_RS25765	COG0523	cobalamin synthesis protein
KF715C_RS25770	COG2879	small protein
KF715C_RS25775	COG1966	Carbon starvation protein
KF715C_RS25785	COG2233	PERMEase
KF715C_RS25795	COG1970	mechanosensitive ion channel activity
KF715C_RS25805	COG2197	response regulator
KF715C_RS25810	COG2813	Specifically methylates the guanine in position
KF715C_RS25820	COG1294	oxidase, subunit
KF715C_RS25825	COG1271	oxidase subunit
KF715C_RS25835	COG2252	PERMEase
KF715C_RS25840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KF715C_RS25845	COG3485	protocatechuate 3,4-dioxygenase
KF715C_RS25850	COG3485	protocatechuate 3,4-dioxygenase
KF715C_RS25855	COG2321	neutral zinc metallopeptidase
KF715C_RS25860	COG0840	transmembrane signaling receptor activity
KF715C_RS25870	COG0583	DNA-binding transcription factor activity
KF715C_RS25875	COG2249	NAD(P)H dehydrogenase (quinone) activity
KF715C_RS25895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KF715C_RS25900	COG2267	carboxylic ester hydrolase activity
KF715C_RS25905	COG0671	phosphoesterase, PA-phosphatase related
KF715C_RS25905	COG2453	phosphatase
KF715C_RS25920	COG4589	Belongs to the CDS family
KF715C_RS25945	COG3047	cAMP biosynthetic process
KF715C_RS25945	COG2885	chlorophyll binding
KF715C_RS25950	COG2199	diguanylate cyclase activity
KF715C_RS25960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KF715C_RS25965	COG1074	ATP-dependent DNA helicase activity
KF715C_RS25970	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KF715C_RS26000	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KF715C_RS26005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KF715C_RS26010	COG1183	phosphatidylcholine synthase activity
KF715C_RS26015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KF715C_RS26025	COG0028	Belongs to the TPP enzyme family
KF715C_RS26030	COG3098	single-species biofilm formation
KF715C_RS26040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KF715C_RS26065	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KF715C_RS26070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KF715C_RS26075	COG4558	Periplasmic binding protein
KF715C_RS26085	COG1489	DNA binding
KF715C_RS26090	COG0436	Aminotransferase
KF715C_RS26100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KF715C_RS26110	COG4191	Histidine kinase
KF715C_RS26120	COG0617	tRNA 3'-terminal CCA addition
KF715C_RS26130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KF715C_RS26135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KF715C_RS26140	COG0166	Belongs to the GPI family
KF715C_RS26145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KF715C_RS26170	COG2823	Periplasmic or secreted lipoprotein
KF715C_RS26175	COG1185	polyribonucleotide nucleotidyltransferase activity
KF715C_RS26180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KF715C_RS26185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KF715C_RS26190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KF715C_RS26195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KF715C_RS26200	COG0195	Participates in both transcription termination and antitermination
KF715C_RS26205	COG0779	Required for maturation of 30S ribosomal subunits
KF715C_RS26220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KF715C_RS26225	COG0149	triose-phosphate isomerase activity
KF715C_RS26230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KF715C_RS26235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KF715C_RS26245	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KF715C_RS26260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KF715C_RS26265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KF715C_RS26270	COG0505	Belongs to the CarA family
KF715C_RS26275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KF715C_RS26280	COG0484	heat shock protein binding
KF715C_RS26285	COG0443	Heat shock 70 kDa protein
KF715C_RS26290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KF715C_RS26295	COG0497	DNA recombination
KF715C_RS26300	COG0735	belongs to the Fur family
KF715C_RS26305	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KF715C_RS26315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KF715C_RS26325	COG1620	l-lactate permease
KF715C_RS26330	COG1304	FMN binding
KF715C_RS26355	COG0582	viral genome integration into host DNA
KF715C_RS26365	COG0659	secondary active sulfate transmembrane transporter activity
KF715C_RS26370	COG0589	response to stress
KF715C_RS26375	COG0494	nUDIX hydrolase
KF715C_RS26380	COG2433	Pfam Transposase IS66
KF715C_RS26415	COG2003	Belongs to the UPF0758 family
KF715C_RS26480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KF715C_RS26580	COG0765	amino acid transport
KF715C_RS26585	COG1126	abc transporter atp-binding protein
KF715C_RS26590	COG0006	proline dipeptidase activity
KF715C_RS26595	COG1902	pentaerythritol trinitrate reductase activity
KF715C_RS26595	COG0446	pyridine nucleotide-disulphide oxidoreductase
KF715C_RS26605	COG4774	siderophore transport
KF715C_RS26765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KF715C_RS26870	COG0604	alcohol dehydrogenase
KF715C_RS26870	COG3321	synthase
KF715C_RS26880	COG1946	Acyl-CoA thioesterase
KF715C_RS26895	COG0123	including yeast histone deacetylase and acetoin utilization protein
KF715C_RS26905	COG0513	Belongs to the DEAD box helicase family
KF715C_RS26910	COG0697	spore germination
KF715C_RS26915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KF715C_RS26925	COG3416	Protein conserved in bacteria
KF715C_RS26935	COG1643	Atp-dependent helicase
KF715C_RS26955	COG1522	sequence-specific DNA binding
KF715C_RS26970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KF715C_RS26975	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS26995	COG2205	protein histidine kinase activity
KF715C_RS26995	COG3850	Histidine kinase
KF715C_RS26995	COG3437	response regulator, receiver
KF715C_RS26995	COG4999	Histidine kinase
KF715C_RS27000	COG0351	phosphomethylpyrimidine kinase
KF715C_RS27005	COG0352	thiamine-phosphate diphosphorylase activity
KF715C_RS27010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KF715C_RS27025	COG1702	phosphate starvation-inducible protein PhoH
KF715C_RS27030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KF715C_RS27035	COG4535	Mg2 and Co2 transporter CorC
KF715C_RS27040	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KF715C_RS27055	COG0495	leucyl-tRNA aminoacylation
KF715C_RS27075	COG2951	lytic endotransglycosylase activity
KF715C_RS27080	COG1619	proteins homologs of microcin C7 resistance protein MccF
KF715C_RS27085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KF715C_RS27090	COG0321	lipoyl(octanoyl) transferase activity
KF715C_RS27095	COG2921	Belongs to the UPF0250 family
KF715C_RS27100	COG1686	Belongs to the peptidase S11 family
KF715C_RS27110	COG2951	lytic endotransglycosylase activity
KF715C_RS27115	COG0772	Belongs to the SEDS family
KF715C_RS27120	COG0768	penicillin binding
KF715C_RS27125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KF715C_RS27135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KF715C_RS27140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KF715C_RS27145	COG2094	Belongs to the DNA glycosylase MPG family
KF715C_RS27150	COG0586	Pfam SNARE associated Golgi protein
KF715C_RS27160	COG1346	cytolysis
KF715C_RS27175	COG2264	protein methyltransferase activity
KF715C_RS27185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KF715C_RS27195	COG0138	bifunctional purine biosynthesis protein purh
KF715C_RS27200	COG0151	Belongs to the GarS family
KF715C_RS27210	COG2095	MarC family integral membrane protein
KF715C_RS27245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KF715C_RS27255	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KF715C_RS27270	COG0330	HflC and HflK could
KF715C_RS27290	COG4774	siderophore transport
KF715C_RS27300	COG1113	amino acid transport
KF715C_RS27320	COG0411	ABC transporter
KF715C_RS27335	COG0789	Transcriptional regulator
KF715C_RS27340	COG0484	heat shock protein binding
KF715C_RS27345	COG0443	Heat shock 70 kDa protein
KF715C_RS27365	COG0697	spore germination
KF715C_RS27370	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KF715C_RS27385	COG2982	Protein involved in outer membrane biogenesis
KF715C_RS27405	COG4221	oxidoreductase activity
KF715C_RS27435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KF715C_RS27440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KF715C_RS27455	COG1032	radical SAM domain protein
KF715C_RS27460	COG5265	(ABC) transporter
KF715C_RS27465	COG0305	Participates in initiation and elongation during chromosome replication
KF715C_RS27470	COG0359	binds to the 23S rRNA
KF715C_RS27480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KF715C_RS27485	COG0360	Binds together with S18 to 16S ribosomal RNA
KF715C_RS27495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KF715C_RS27500	COG0557	exoribonuclease II activity
KF715C_RS27515	COG1840	ABC-type Fe3 transport system, periplasmic component
KF715C_RS27520	COG1178	ABC-type Fe3 transport system permease component
KF715C_RS27525	COG0840	transmembrane signaling receptor activity
KF715C_RS27530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KF715C_RS27535	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KF715C_RS27540	COG0330	HflC and HflK could
KF715C_RS27545	COG0330	HflC and HflK could
KF715C_RS27550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KF715C_RS27555	COG1923	regulation of RNA biosynthetic process
KF715C_RS27560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KF715C_RS27565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KF715C_RS27570	COG0860	N-Acetylmuramoyl-L-alanine amidase
KF715C_RS27575	COG0802	atpase or kinase
KF715C_RS27580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KF715C_RS27580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KF715C_RS27590	COG2860	membrane
KF715C_RS27595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KF715C_RS27600	COG1162	GTPase activity
KF715C_RS27610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KF715C_RS27625	COG0688	phosphatidylethanolamine metabolic process
KF715C_RS27630	COG0560	Phosphoserine phosphatase
KF715C_RS27630	COG3830	Belongs to the UPF0237 family
KF715C_RS27650	COG3577	Aspartyl protease
KF715C_RS27665	COG3150	esterase
KF715C_RS27670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KF715C_RS27680	COG0494	nUDIX hydrolase
KF715C_RS27695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KF715C_RS27700	COG1538	Outer membrane efflux protein
KF715C_RS27705	COG1519	Transferase
KF715C_RS27735	COG0667	Aldo Keto reductase
KF715C_RS27745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KF715C_RS27745	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KF715C_RS27750	COG1132	(ABC) transporter
KF715C_RS27765	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS27790	COG0438	transferase activity, transferring glycosyl groups
KF715C_RS27795	COG2192	nodulation
KF715C_RS27800	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KF715C_RS27810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KF715C_RS27815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KF715C_RS27815	COG0506	proline dehydrogenase activity
KF715C_RS27815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KF715C_RS27830	COG1960	acyl-CoA dehydrogenase activity
KF715C_RS27840	COG0312	modulator of DNA gyrase
KF715C_RS27845	COG0477	Major facilitator Superfamily
KF715C_RS27850	COG0513	Belongs to the DEAD box helicase family
KF715C_RS27855	COG2081	HI0933 family
KF715C_RS27860	COG1289	transmembrane transporter activity
KF715C_RS27865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS27870	COG2153	protein acetylation
KF715C_RS27880	COG1451	nucleotide metabolic process
KF715C_RS27905	COG0126	phosphoglycerate kinase activity
KF715C_RS27920	COG0640	Transcriptional regulator
KF715C_RS27925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KF715C_RS27930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KF715C_RS27970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KF715C_RS27975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KF715C_RS27990	COG0513	Belongs to the DEAD box helicase family
KF715C_RS27995	COG2353	YceI-like domain
KF715C_RS28000	COG3038	cytochrome b561
KF715C_RS28020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KF715C_RS28025	COG1272	protein, Hemolysin III
KF715C_RS28035	COG0643	Histidine kinase
KF715C_RS28035	COG2198	Histidine kinase
KF715C_RS28035	COG0784	Response regulator, receiver
KF715C_RS28060	COG0189	ligase activity
KF715C_RS28070	COG1678	Uncharacterized ACR, COG1678
KF715C_RS28075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KF715C_RS28080	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KF715C_RS28085	COG0540	Belongs to the ATCase OTCase family
KF715C_RS28090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KF715C_RS28095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KF715C_RS28100	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KF715C_RS28150	COG2226	methyltransferase
KF715C_RS28160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KF715C_RS28165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KF715C_RS28170	COG0140	phosphoribosyl-ATP diphosphatase activity
KF715C_RS28175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KF715C_RS28195	COG0840	transmembrane signaling receptor activity
KF715C_RS28200	COG0840	transmembrane signaling receptor activity
KF715C_RS28205	COG1126	abc transporter atp-binding protein
KF715C_RS28210	COG0765	amino acid transport
KF715C_RS28220	COG2943	transferase activity, transferring hexosyl groups
KF715C_RS28225	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KF715C_RS28230	COG1490	D-aminoacyl-tRNA deacylase activity
KF715C_RS28250	COG1228	amidohydrolase
KF715C_RS28260	COG2986	histidine ammonia-lyase
KF715C_RS28265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KF715C_RS28275	COG2188	Transcriptional regulator
KF715C_RS28280	COG0402	S-adenosylhomocysteine deaminase activity
KF715C_RS28305	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KF715C_RS28310	COG0058	SHG alpha-glucan phosphorylase activity
KF715C_RS28320	COG1217	gtp-binding protein TYPA
KF715C_RS28325	COG0301	tRNA thio-modification
KF715C_RS28325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KF715C_RS28335	COG3852	Histidine kinase
KF715C_RS28350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KF715C_RS28355	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KF715C_RS28365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KF715C_RS28370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KF715C_RS28375	COG4942	peptidase
KF715C_RS28380	COG0793	Belongs to the peptidase S41A family
KF715C_RS28385	COG2861	carbohydrate metabolic process
KF715C_RS28395	COG2948	multi-organism process
KF715C_RS28410	COG3846	protein secretion by the type IV secretion system
KF715C_RS28425	COG3451	type IV secretory pathway VirB4
KF715C_RS28435	COG3838	Conjugal transfer protein Trbc
KF715C_RS28440	COG4962	Type ii secretion system protein e
KF715C_RS28465	COG0583	DNA-binding transcription factor activity
KF715C_RS28470	COG1846	Transcriptional regulator
KF715C_RS28475	COG2814	Major facilitator Superfamily
KF715C_RS28520	COG1192	Involved in chromosome partitioning
KF715C_RS28555	COG5489	Protein of unknown function (DUF736)
KF715C_RS28570	COG1475	DNA binding
KF715C_RS28615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KF715C_RS28620	COG1309	transcriptional regulator
KF715C_RS28625	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS28630	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KF715C_RS28640	COG3263	regulation of cellular component size
KF715C_RS28645	COG3264	Mechanosensitive ion channel
KF715C_RS28645	COG1196	nuclear chromosome segregation
KF715C_RS28650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KF715C_RS28655	COG3118	belongs to the thioredoxin family
KF715C_RS28660	COG1192	Involved in chromosome partitioning
KF715C_RS28665	COG0583	DNA-binding transcription factor activity
KF715C_RS28670	COG2814	Major facilitator Superfamily
KF715C_RS28680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KF715C_RS28685	COG0493	'glutamate synthase
KF715C_RS28690	COG0070	glutamate synthase
KF715C_RS28690	COG0069	glutamate synthase activity
KF715C_RS28690	COG0067	glutamate synthase
KF715C_RS28700	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KF715C_RS28705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KF715C_RS28735	COG3344	reverse transcriptase
KF715C_RS28745	COG0281	malic enzyme
KF715C_RS28755	COG0254	rRNA binding
KF715C_RS28760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KF715C_RS28765	COG0018	arginyl-trna synthetase
KF715C_RS28780	COG0791	NLP P60 protein
KF715C_RS28805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KF715C_RS28810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KF715C_RS28810	COG2813	Specifically methylates the guanine in position
KF715C_RS28820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KF715C_RS28825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KF715C_RS28835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KF715C_RS28840	COG2022	thiamine diphosphate biosynthetic process
KF715C_RS28845	COG2104	thiamine diphosphate biosynthetic process
KF715C_RS28845	COG2022	thiamine diphosphate biosynthetic process
KF715C_RS28850	COG2363	Small membrane protein
KF715C_RS28855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KF715C_RS28865	COG2177	Part of the ABC transporter FtsEX involved in
KF715C_RS28870	COG2884	Cell division ATP-binding protein ftsE
KF715C_RS28875	COG0552	protein localization to endoplasmic reticulum
KF715C_RS28885	COG0612	Peptidase, M16
KF715C_RS28890	COG0612	Peptidase, M16
KF715C_RS28895	COG0742	ribosomal rna small subunit methyltransferase
KF715C_RS28900	COG0612	Peptidase, M16
KF715C_RS28930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KF715C_RS28935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KF715C_RS28940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KF715C_RS28950	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KF715C_RS28960	COG0129	dihydroxy-acid dehydratase activity
KF715C_RS28970	COG1823	symporter activity
KF715C_RS28985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KF715C_RS28990	COG1840	ABC-type Fe3 transport system, periplasmic component
KF715C_RS28995	COG1178	ABC-type Fe3 transport system permease component
KF715C_RS29000	COG3842	ATPase activity
KF715C_RS29015	COG0789	Transcriptional regulator
KF715C_RS29020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KF715C_RS29025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KF715C_RS29030	COG0730	response to heat
KF715C_RS29040	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KF715C_RS29045	COG0494	nUDIX hydrolase
KF715C_RS29060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KF715C_RS29065	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KF715C_RS29070	COG3204	pilus organization
KF715C_RS29075	COG3204	pilus organization
KF715C_RS29080	COG0179	Fumarylacetoacetate (FAA) hydrolase
KF715C_RS29085	COG0277	FAD linked oxidase domain protein
KF715C_RS29090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KF715C_RS29100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS29105	COG1683	Conserved Protein
KF715C_RS29140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KF715C_RS29145	COG1126	abc transporter atp-binding protein
KF715C_RS29150	COG0765	amino acid transport
KF715C_RS29155	COG0765	amino acid transport
KF715C_RS29165	COG3829	transcription factor binding
KF715C_RS29190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KF715C_RS29195	COG4208	sulfate ABC transporter
KF715C_RS29205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KF715C_RS29215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS29240	COG1177	transmembrane transport
KF715C_RS29245	COG1176	ABC-type spermidine putrescine transport system, permease component I
KF715C_RS29250	COG3842	ATPase activity
KF715C_RS29270	COG0174	glutamine synthetase
KF715C_RS29280	COG0174	glutamine synthetase
KF715C_RS29285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KF715C_RS29285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KF715C_RS29290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KF715C_RS29300	COG1522	sequence-specific DNA binding
KF715C_RS29310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KF715C_RS29320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KF715C_RS29320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KF715C_RS29325	COG0509	glycine decarboxylation via glycine cleavage system
KF715C_RS29330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KF715C_RS29335	COG1178	ABC-type Fe3 transport system permease component
KF715C_RS29345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KF715C_RS29355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KF715C_RS29360	COG0006	proline dipeptidase activity
KF715C_RS29365	COG3079	Belongs to the UPF0149 family
KF715C_RS29385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KF715C_RS29395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS29400	COG0842	Transport permease protein
KF715C_RS29400	COG1129	ABC transporter
KF715C_RS29405	COG0842	Transport permease protein
KF715C_RS29430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KF715C_RS29455	COG0248	Ppx GppA phosphatase
KF715C_RS29460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KF715C_RS29475	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KF715C_RS29480	COG1671	Belongs to the UPF0178 family
KF715C_RS29485	COG3072	Adenylate cyclase
KF715C_RS29490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KF715C_RS29500	COG1965	Belongs to the frataxin family
KF715C_RS29510	COG0019	diaminopimelate decarboxylase activity
KF715C_RS29515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KF715C_RS29525	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KF715C_RS29530	COG0546	phosphoglycolate phosphatase activity
KF715C_RS29540	COG3344	reverse transcriptase
KF715C_RS29545	COG0004	ammonium transporteR
KF715C_RS29550	COG0347	Belongs to the P(II) protein family
KF715C_RS29575	COG0606	chelatase, subunit chli
KF715C_RS29595	COG3344	reverse transcriptase
KF715C_RS29605	COG0583	DNA-binding transcription factor activity
KF715C_RS29620	COG1335	isochorismatase
KF715C_RS29630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS29635	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS29640	COG0583	DNA-binding transcription factor activity
KF715C_RS29645	COG5383	Protein conserved in bacteria
KF715C_RS29650	COG0583	DNA-binding transcription factor activity
KF715C_RS29655	COG0534	Mate efflux family protein
KF715C_RS29670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KF715C_RS29675	COG0427	acetyl-CoA hydrolase
KF715C_RS29695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS29710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KF715C_RS29720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KF715C_RS29725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KF715C_RS29735	COG1012	belongs to the aldehyde dehydrogenase family
KF715C_RS29745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KF715C_RS29750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KF715C_RS29755	COG0747	negative chemotaxis
KF715C_RS29760	COG2003	Belongs to the UPF0758 family
KF715C_RS29765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KF715C_RS29770	COG0756	dUTP diphosphatase activity
KF715C_RS29775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KF715C_RS29780	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KF715C_RS29785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KF715C_RS29790	COG0708	Exodeoxyribonuclease III
KF715C_RS29795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KF715C_RS29800	COG1561	YicC-like family, N-terminal region
KF715C_RS29805	COG0194	GDP metabolic process
KF715C_RS29815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KF715C_RS29820	COG0174	glutamine synthetase
KF715C_RS29830	COG1758	RNA polymerase activity
KF715C_RS29835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KF715C_RS29860	COG0848	biopolymer transport protein
KF715C_RS29870	COG0583	DNA-binding transcription factor activity
KF715C_RS29875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KF715C_RS29905	COG3161	chorismate lyase activity
KF715C_RS29910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KF715C_RS29930	COG1253	flavin adenine dinucleotide binding
KF715C_RS29935	COG0739	heme binding
KF715C_RS29945	COG0704	Plays a role in the regulation of phosphate uptake
KF715C_RS29950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KF715C_RS29955	COG0581	inorganic phosphate transmembrane transporter activity
KF715C_RS29970	COG0477	Major facilitator Superfamily
KF715C_RS29975	COG1607	acyl-coa hydrolase
KF715C_RS30005	COG0583	DNA-binding transcription factor activity
KF715C_RS30010	COG1027	Aspartate ammonia-lyase
KF715C_RS30050	COG5016	pyruvate
KF715C_RS30050	COG0511	ligase activity, forming carbon-carbon bonds
KF715C_RS30055	COG0439	Biotin carboxylase
KF715C_RS30060	COG0583	DNA-binding transcription factor activity
KF715C_RS30075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KF715C_RS30085	COG0210	DNA helicase
KF715C_RS30100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KF715C_RS30100	COG4651	solute:proton antiporter activity
KF715C_RS30105	COG1607	acyl-coa hydrolase
KF715C_RS30110	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KF715C_RS30120	COG0523	cobalamin synthesis protein
KF715C_RS30140	COG1469	GTP cyclohydrolase I activity
KF715C_RS30150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KF715C_RS30155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KF715C_RS30160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KF715C_RS30170	COG0640	Transcriptional regulator
KF715C_RS30175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KF715C_RS30180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KF715C_RS30185	COG0431	NADPH-dependent FMN reductase
KF715C_RS30195	COG2072	flavoprotein involved in K transport
KF715C_RS30200	COG1247	-acetyltransferase
KF715C_RS30220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS30225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS30315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KF715C_RS30320	COG1349	DNA-binding transcription factor activity
KF715C_RS30325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KF715C_RS30330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KF715C_RS30335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KF715C_RS30340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KF715C_RS30345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KF715C_RS30350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KF715C_RS30355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KF715C_RS30365	COG0356	it plays a direct role in the translocation of protons across the membrane
KF715C_RS30370	COG3312	ion transport
KF715C_RS30375	COG1475	DNA binding
KF715C_RS30380	COG1192	Involved in chromosome partitioning
KF715C_RS30385	COG0357	Ribosomal RNA small subunit methyltransferase G
KF715C_RS30390	COG0445	tRNA wobble uridine modification
KF715C_RS30395	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KF715C_RS30400	COG0706	membrane insertase activity
KF715C_RS30405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KF715C_RS30410	COG0594	ribonuclease P activity
KF715C_RS30415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KF715C_RS30485	COG0515	serine threonine protein kinase
KF715C_RS30515	COG0582	viral genome integration into host DNA
KF715C_RS30520	COG1802	Transcriptional regulator
KF715C_RS30530	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KF715C_RS30540	COG2146	nitrite reductase [NAD(P)H] activity
KF715C_RS30545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KF715C_RS30550	COG1028	Short-chain dehydrogenase reductase Sdr
KF715C_RS30555	COG0346	lactoylglutathione lyase activity
KF715C_RS30580	COG3039	Transposase
KF715C_RS30595	COG3344	reverse transcriptase
KF715C_RS30680	COG0277	FAD linked oxidase domain protein
KF715C_RS30750	COG2003	Belongs to the UPF0758 family
KF715C_RS31525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KF715C_RS31680	COG3344	reverse transcriptase
KF715C_RS32055	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KF715C_RS32095	COG3451	type IV secretory pathway VirB4
KF715C_RS32110	COG1192	Involved in chromosome partitioning
KF715C_RS32115	COG1475	DNA binding
KF715C_RS32160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KF715C_RS32190	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KF715C_RS32195	COG3657	addiction module killer protein
KF715C_RS32255	COG0629	single-stranded DNA binding
KF715C_RS32335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KF715C_RS32340	COG4569	acetaldehyde dehydrogenase (acetylating) activity
KF715C_RS32395	COG2826	transposase and inactivated derivatives, IS30 family
KF715C_RS32420	COG0322	excinuclease ABC activity
KF715C_RS32440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KF715C_RS32520	COG3344	reverse transcriptase
KF715C_RS32525	COG0330	HflC and HflK could
KF715C_RS32530	COG1074	ATP-dependent DNA helicase activity
KF715C_RS32620	COG0641	radical SAM
KF715C_RS32625	COG0641	radical SAM
KF715C_RS32655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KF715C_RS32750	COG2433	Pfam Transposase IS66
KF715C_RS32860	COG1192	Involved in chromosome partitioning
KF715C_RS32870	COG1475	DNA binding
KF715C_RS32880	COG0745	RESPONSE REGULATOR receiver
KF715C_RS32895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KF715C_RS32900	COG0643	Histidine kinase
KF715C_RS32900	COG2198	Histidine kinase
KF715C_RS32905	COG2201	protein-glutamate methylesterase activity
KF715C_RS33035	COG0740	serine-type endopeptidase activity
KF715C_RS33045	COG0629	single-stranded DNA binding
KF715C_RS33095	COG0583	DNA-binding transcription factor activity
KF715C_RS33105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KF715C_RS33140	COG0625	glutathione transferase activity
KF715C_RS33155	COG3344	reverse transcriptase
KF715C_RS33160	COG2233	PERMEase
KF715C_RS33165	COG2186	Transcriptional regulator
KF715C_RS33180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KF715C_RS33195	COG0582	viral genome integration into host DNA
KF715C_RS33210	COG0551	DNA topoisomerase type I activity
KF715C_RS33210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KF715C_RS33235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KF715C_RS33240	COG1192	Involved in chromosome partitioning
KF715C_RS33245	COG1475	DNA binding
KF715C_RS33355	COG0210	DNA helicase
KF715C_RS33380	COG3039	Transposase
KF715C_RS33500	COG3039	Transposase
KF715C_RS33565	COG0305	Participates in initiation and elongation during chromosome replication
KF715C_RS33570	COG0305	Participates in initiation and elongation during chromosome replication
KF715C_RS33595	COG0789	Transcriptional regulator
KF715C_RS33635	COG1815	bacterial-type flagellum-dependent cell motility
KF715C_RS33680	COG1403	HNH endonuclease
KF715C_RS33685	COG2963	transposase activity
KF715C_RS33820	COG1230	cation diffusion facilitator family transporter
KF715C_RS33835	COG0640	Transcriptional regulator
KF715C_RS33840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KF715C_RS33845	COG0798	PFAM Bile acid sodium symporter
KF715C_RS33850	COG0431	NADPH-dependent FMN reductase
KF715C_RS33860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KF715C_RS33955	COG0463	Glycosyl transferase, family 2
KF715C_RS34005	COG2194	sulfuric ester hydrolase activity
KF715C_RS34035	COG1403	HNH endonuclease
KF715C_RS34055	COG3039	Transposase
KF715C_RS34100	COG3344	reverse transcriptase
KF715C_RS34115	COG3091	SprT-like family
KF715C_RS34145	COG2974	May be involved in recombination
KF715C_RS34215	COG2217	Heavy metal translocating P-type atpase
KF715C_RS34220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KF715C_RS34225	COG1074	ATP-dependent DNA helicase activity
KF715C_RS34255	COG3039	Transposase
KF715C_RS34265	COG2132	Multicopper oxidase
KF715C_RS34300	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KF715C_RS34305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KF715C_RS34380	COG0681	Belongs to the peptidase S26 family
KF715C_RS34430	COG3344	reverse transcriptase
KF715C_RS34445	COG3344	reverse transcriptase
KF715C_RS34480	COG3344	reverse transcriptase
KF715C_RS34620	COG0681	Belongs to the peptidase S26 family
KF715C_RS34685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KF715C_RS34690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KF715C_RS34720	COG0582	viral genome integration into host DNA
KF715C_RS34835	COG0489	protein tyrosine kinase activity
KF715C_RS34980	COG3179	chitinase
KF715C_RS35020	COG3081	Nucleoid-associated protein
KF715C_RS35305	COG0629	single-stranded DNA binding
KF715C_RS35315	COG2974	May be involved in recombination
KF715C_RS35350	COG2948	multi-organism process
KF715C_RS35355	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KF715C_RS35425	COG1475	DNA binding
KF715C_RS35430	COG1192	Involved in chromosome partitioning
KF715C_RS35490	COG3451	type IV secretory pathway VirB4