locus-tag	class	description
YSA_RS00025	COG0488	(ABC) transporter
YSA_RS00030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YSA_RS00040	COG0583	DNA-binding transcription factor activity
YSA_RS00045	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
YSA_RS00065	COG3064	Membrane
YSA_RS00110	COG1309	transcriptional regulator
YSA_RS00120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YSA_RS00130	COG3257	ureidoglycine aminohydrolase activity
YSA_RS00140	COG1522	sequence-specific DNA binding
YSA_RS00145	COG2423	ornithine cyclodeaminase activity
YSA_RS00150	COG0583	DNA-binding transcription factor activity
YSA_RS00155	COG0405	Gamma-glutamyltransferase
YSA_RS00165	COG2207	Transcriptional regulator
YSA_RS00170	COG0789	Transcriptional regulator
YSA_RS00180	COG1285	pathogenesis
YSA_RS00190	COG0348	domain, Protein
YSA_RS00195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS00205	COG4191	Histidine kinase
YSA_RS00205	COG0784	Response regulator, receiver
YSA_RS00210	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS00220	COG1566	PFAM secretion protein HlyD family protein
YSA_RS00225	COG1846	Transcriptional regulator
YSA_RS00230	COG4566	intracellular signal transduction
YSA_RS00240	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS00245	COG1960	acyl-CoA dehydrogenase activity
YSA_RS00255	COG2056	Na+-H+ antiporter family
YSA_RS00265	COG0840	transmembrane signaling receptor activity
YSA_RS00275	COG4176	ABC-type proline glycine betaine transport system permease component
YSA_RS00305	COG1280	lysine exporter protein (LysE YggA)
YSA_RS00310	COG2814	Major facilitator Superfamily
YSA_RS00315	COG0583	DNA-binding transcription factor activity
YSA_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS00370	COG4774	siderophore transport
YSA_RS00375	COG3712	iron ion homeostasis
YSA_RS00380	COG1595	DNA-templated transcription, initiation
YSA_RS00430	COG2814	Major facilitator Superfamily
YSA_RS00435	COG0814	amino acid
YSA_RS00470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS00475	COG1126	abc transporter atp-binding protein
YSA_RS00490	COG0784	Response regulator, receiver
YSA_RS00490	COG2205	protein histidine kinase activity
YSA_RS00515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YSA_RS00520	COG0581	inorganic phosphate transmembrane transporter activity
YSA_RS00530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YSA_RS00560	COG2271	Major facilitator Superfamily
YSA_RS00575	COG1522	sequence-specific DNA binding
YSA_RS00635	COG0454	-acetyltransferase
YSA_RS00660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YSA_RS00665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YSA_RS00670	COG3118	belongs to the thioredoxin family
YSA_RS00670	COG0457	Tetratricopeptide repeat
YSA_RS00675	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YSA_RS00680	COG1215	transferase activity, transferring glycosyl groups
YSA_RS00700	COG2194	sulfuric ester hydrolase activity
YSA_RS00715	COG1132	(ABC) transporter
YSA_RS00810	COG1414	Transcriptional regulator
YSA_RS00815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YSA_RS00820	COG1053	succinate dehydrogenase
YSA_RS00830	COG1053	succinate dehydrogenase
YSA_RS00845	COG0673	inositol 2-dehydrogenase activity
YSA_RS00855	COG1053	succinate dehydrogenase
YSA_RS00860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YSA_RS00865	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS00880	COG0531	amino acid
YSA_RS00885	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS00910	COG2194	sulfuric ester hydrolase activity
YSA_RS00920	COG3008	intermembrane lipid transfer
YSA_RS00925	COG2995	paraquat-inducible protein a
YSA_RS00945	COG0346	lactoylglutathione lyase activity
YSA_RS00955	COG0477	Major facilitator Superfamily
YSA_RS00965	COG0596	Alpha beta hydrolase
YSA_RS00975	COG0210	DNA helicase
YSA_RS01030	COG3185	4-Hydroxyphenylpyruvate dioxygenase
YSA_RS01030	COG1082	Xylose isomerase domain protein TIM barrel
YSA_RS01035	COG0477	Major facilitator Superfamily
YSA_RS01040	COG0076	glutamate decarboxylase activity
YSA_RS01045	COG0583	DNA-binding transcription factor activity
YSA_RS01050	COG0217	transcriptional regulatory protein
YSA_RS01055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS01060	COG2814	Major facilitator Superfamily
YSA_RS01065	COG0583	DNA-binding transcription factor activity
YSA_RS01075	COG4106	trans-aconitate 2-methyltransferase activity
YSA_RS01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS01130	COG0625	glutathione transferase activity
YSA_RS01135	COG2814	Major facilitator Superfamily
YSA_RS01140	COG0583	DNA-binding transcription factor activity
YSA_RS01145	COG1309	transcriptional regulator
YSA_RS01150	COG1574	metal-dependent hydrolase with the TIM-barrel fold
YSA_RS01175	COG2873	o-acetylhomoserine
YSA_RS01195	COG1418	mRNA catabolic process
YSA_RS01205	COG2066	Belongs to the glutaminase family
YSA_RS01215	COG3384	dioxygenase
YSA_RS01225	COG0583	DNA-binding transcription factor activity
YSA_RS01230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YSA_RS01235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YSA_RS01240	COG2828	Protein conserved in bacteria
YSA_RS01250	COG0302	gtp cyclohydrolase
YSA_RS01300	COG1942	4-Oxalocrotonate Tautomerase
YSA_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS01325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YSA_RS01330	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS01335	COG1522	sequence-specific DNA binding
YSA_RS01340	COG3608	succinylglutamate desuccinylase aspartoacylase
YSA_RS01345	COG0006	proline dipeptidase activity
YSA_RS01350	COG2423	ornithine cyclodeaminase activity
YSA_RS01355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YSA_RS01360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS01365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS01370	COG0765	amino acid transport
YSA_RS01375	COG0765	amino acid transport
YSA_RS01380	COG1126	abc transporter atp-binding protein
YSA_RS01385	COG3039	Transposase
YSA_RS01410	COG0659	secondary active sulfate transmembrane transporter activity
YSA_RS01425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YSA_RS01440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YSA_RS01445	COG0798	PFAM Bile acid sodium symporter
YSA_RS01450	COG0431	NADPH-dependent FMN reductase
YSA_RS01460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YSA_RS01495	COG1294	oxidase, subunit
YSA_RS01580	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS01590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YSA_RS01605	COG2826	transposase and inactivated derivatives, IS30 family
YSA_RS01625	COG1192	Involved in chromosome partitioning
YSA_RS01670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YSA_RS01925	COG1358	cellular component organization or biogenesis
YSA_RS01975	COG0776	regulation of translation
YSA_RS01980	COG0072	phenylalanine-tRNA ligase activity
YSA_RS01985	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YSA_RS01990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YSA_RS01995	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YSA_RS02000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YSA_RS02005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YSA_RS02015	COG1278	Cold shock
YSA_RS02035	COG1869	D-ribose catabolic process
YSA_RS02040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YSA_RS02045	COG1609	Transcriptional regulator
YSA_RS02050	COG1172	Belongs to the binding-protein-dependent transport system permease family
YSA_RS02055	COG1129	ABC transporter
YSA_RS02065	COG0252	asparaginase activity
YSA_RS02070	COG3604	Transcriptional regulator
YSA_RS02075	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
YSA_RS02080	COG2116	formate transmembrane transporter activity
YSA_RS02095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YSA_RS02115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS02130	COG1253	flavin adenine dinucleotide binding
YSA_RS02140	COG0583	DNA-binding transcription factor activity
YSA_RS02145	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
YSA_RS02150	COG3132	Protein of unknown function, DUF480
YSA_RS02160	COG3634	alkyl hydroperoxide reductase activity
YSA_RS02170	COG0861	Integral membrane protein TerC family
YSA_RS02185	COG1104	cysteine desulfurase activity
YSA_RS02190	COG5654	RES domain protein
YSA_RS02195	COG5642	Protein of unknown function (DUF2384)
YSA_RS02205	COG0583	DNA-binding transcription factor activity
YSA_RS02220	COG2814	Major facilitator Superfamily
YSA_RS02230	COG1064	alcohol dehydrogenase
YSA_RS02235	COG2207	Transcriptional regulator
YSA_RS02250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YSA_RS02260	COG4774	siderophore transport
YSA_RS02275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YSA_RS02280	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YSA_RS02300	COG1192	Involved in chromosome partitioning
YSA_RS02305	COG0477	Major facilitator Superfamily
YSA_RS02325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YSA_RS02330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YSA_RS02360	COG2259	Doxx family
YSA_RS02370	COG3220	belongs to the UPF0276 family
YSA_RS02400	COG0417	DNA replication proofreading
YSA_RS02405	COG2814	Major facilitator Superfamily
YSA_RS02410	COG0583	DNA-binding transcription factor activity
YSA_RS02415	COG0583	DNA-binding transcription factor activity
YSA_RS02465	COG1999	signal sequence binding
YSA_RS02470	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
YSA_RS02470	COG0316	Belongs to the HesB IscA family
YSA_RS02475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YSA_RS02520	COG2814	Major facilitator Superfamily
YSA_RS02525	COG2223	nitrite transmembrane transporter activity
YSA_RS02530	COG2207	Transcriptional regulator
YSA_RS02535	COG2866	Carboxypeptidase
YSA_RS02575	COG4251	negative regulation of phosphorylation
YSA_RS02580	COG0745	RESPONSE REGULATOR receiver
YSA_RS02600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YSA_RS02615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
YSA_RS02615	COG0617	tRNA 3'-terminal CCA addition
YSA_RS02615	COG0517	IMP dehydrogenase activity
YSA_RS02645	COG0720	synthase
YSA_RS02665	COG2079	MmgE PrpD family protein
YSA_RS02680	COG0372	Belongs to the citrate synthase family
YSA_RS02690	COG1802	Transcriptional regulator
YSA_RS02695	COG4067	protein conserved in archaea
YSA_RS02695	COG0189	ligase activity
YSA_RS02725	COG0589	response to stress
YSA_RS02730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YSA_RS02735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YSA_RS02750	COG1376	ErfK ybiS ycfS ynhG family protein
YSA_RS02750	COG1388	LysM domain
YSA_RS02765	COG4181	ATPase activity
YSA_RS02770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YSA_RS02775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YSA_RS02785	COG2259	Doxx family
YSA_RS02790	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YSA_RS02800	COG0840	transmembrane signaling receptor activity
YSA_RS02830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YSA_RS02840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YSA_RS02845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YSA_RS02850	COG0740	serine-type endopeptidase activity
YSA_RS02855	COG0544	peptidyl-prolyl cis-trans isomerase activity
YSA_RS02885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YSA_RS02900	COG0395	ABC-type sugar transport system, permease component
YSA_RS02910	COG3842	ATPase activity
YSA_RS02915	COG3842	ATPase activity
YSA_RS02920	COG3284	Transcriptional regulator
YSA_RS02930	COG0840	transmembrane signaling receptor activity
YSA_RS02945	COG2186	Transcriptional regulator
YSA_RS02965	COG0583	DNA-binding transcription factor activity
YSA_RS02970	COG0840	transmembrane signaling receptor activity
YSA_RS02975	COG3949	Membrane
YSA_RS02980	COG0251	oxidation-reduction process
YSA_RS02995	COG0730	response to heat
YSA_RS03085	COG1335	isochorismatase
YSA_RS03100	COG2111	Na H antiporter
YSA_RS03100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YSA_RS03105	COG1006	Multisubunit Na H antiporter MnhC subunit
YSA_RS03110	COG0651	ATP synthesis coupled electron transport
YSA_RS03120	COG2212	antiporter activity
YSA_RS03125	COG1320	monovalent cation:proton antiporter activity
YSA_RS03155	COG1024	Enoyl-CoA hydratase
YSA_RS03160	COG1960	acyl-CoA dehydrogenase activity
YSA_RS03165	COG0183	Belongs to the thiolase family
YSA_RS03175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YSA_RS03185	COG2207	Transcriptional regulator
YSA_RS03190	COG0583	DNA-binding transcription factor activity
YSA_RS03195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YSA_RS03200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YSA_RS03210	COG0826	peptidase U32
YSA_RS03225	COG1238	metal cluster binding
YSA_RS03230	COG0596	Alpha beta hydrolase
YSA_RS03240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YSA_RS03245	COG2133	pyrroloquinoline quinone binding
YSA_RS03255	COG0010	Belongs to the arginase family
YSA_RS03275	COG1595	DNA-templated transcription, initiation
YSA_RS03300	COG0589	response to stress
YSA_RS03310	COG3383	formate dehydrogenase (NAD+) activity
YSA_RS03340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
YSA_RS03345	COG0174	glutamine synthetase
YSA_RS03355	COG0583	DNA-binding transcription factor activity
YSA_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS03390	COG3328	transposase activity
YSA_RS03395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YSA_RS03400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YSA_RS03415	COG4566	intracellular signal transduction
YSA_RS03425	COG2853	Lipoprotein
YSA_RS03440	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YSA_RS03440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YSA_RS03460	COG4591	ABC-type transport system involved in lipoprotein release permease component
YSA_RS03465	COG1136	(ABC) transporter
YSA_RS03470	COG4591	ABC-type transport system involved in lipoprotein release permease component
YSA_RS03480	COG0584	glycerophosphoryl diester phosphodiesterase
YSA_RS03485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YSA_RS03490	COG1477	protein flavinylation
YSA_RS03500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YSA_RS03510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YSA_RS03525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YSA_RS03555	COG0183	Belongs to the thiolase family
YSA_RS03560	COG1250	3-hydroxyacyl-CoA dehydrogenase
YSA_RS03560	COG1024	Enoyl-CoA hydratase
YSA_RS03570	COG0589	response to stress
YSA_RS03575	COG0488	(ABC) transporter
YSA_RS03580	COG0741	lytic transglycosylase activity
YSA_RS03585	COG3217	Mosc domain protein beta barrel domain protein
YSA_RS03585	COG0633	Ferredoxin
YSA_RS03590	COG0835	chemotaxis
YSA_RS03590	COG0784	Response regulator, receiver
YSA_RS03600	COG3851	Histidine kinase
YSA_RS03605	COG2197	response regulator
YSA_RS03610	COG1597	lipid kinase activity
YSA_RS03615	COG0438	transferase activity, transferring glycosyl groups
YSA_RS03625	COG0521	Mo-molybdopterin cofactor biosynthetic process
YSA_RS03645	COG1132	(ABC) transporter
YSA_RS03650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YSA_RS03655	COG0425	Belongs to the sulfur carrier protein TusA family
YSA_RS03660	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
YSA_RS03670	COG0840	transmembrane signaling receptor activity
YSA_RS03695	COG0004	ammonium transporteR
YSA_RS03720	COG2197	response regulator
YSA_RS03725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS03725	COG2205	protein histidine kinase activity
YSA_RS03730	COG3171	Protein conserved in bacteria
YSA_RS03735	COG2027	D-alanyl-D-alanine carboxypeptidase
YSA_RS03745	COG0116	Belongs to the methyltransferase superfamily
YSA_RS03745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YSA_RS03750	COG0167	dihydroorotate dehydrogenase activity
YSA_RS03755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YSA_RS03755	COG1116	anion transmembrane transporter activity
YSA_RS03760	COG3707	response regulator
YSA_RS03765	COG2223	nitrite transmembrane transporter activity
YSA_RS03790	COG0668	transmembrane transport
YSA_RS03805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YSA_RS03820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YSA_RS03835	COG0583	DNA-binding transcription factor activity
YSA_RS03840	COG0019	diaminopimelate decarboxylase activity
YSA_RS03845	COG1595	DNA-templated transcription, initiation
YSA_RS03910	COG2188	Transcriptional regulator
YSA_RS03915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YSA_RS03925	COG0789	Transcriptional regulator
YSA_RS03930	COG3237	CsbD-like
YSA_RS03940	COG2851	Citrate transporter
YSA_RS03945	COG1301	dicarboxylic acid transport
YSA_RS03950	COG2828	Protein conserved in bacteria
YSA_RS03955	COG0583	DNA-binding transcription factor activity
YSA_RS03965	COG0246	Mannitol dehydrogenase
YSA_RS03970	COG0183	Belongs to the thiolase family
YSA_RS03980	COG1454	alcohol dehydrogenase
YSA_RS03985	COG1960	acyl-CoA dehydrogenase activity
YSA_RS03990	COG1024	Enoyl-CoA hydratase
YSA_RS03990	COG1250	3-hydroxyacyl-CoA dehydrogenase
YSA_RS03995	COG0583	DNA-binding transcription factor activity
YSA_RS04000	COG2015	COG2015, Alkyl sulfatase and related hydrolases
YSA_RS04010	COG2149	membrane
YSA_RS04035	COG1960	acyl-CoA dehydrogenase activity
YSA_RS04040	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS04050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YSA_RS04055	COG3135	benzoate transporter
YSA_RS04070	COG0714	Associated with various cellular activities
YSA_RS04105	COG0420	3'-5' exonuclease activity
YSA_RS04120	COG2706	6-phosphogluconolactonase activity
YSA_RS04140	COG0308	aminopeptidase N
YSA_RS04150	COG3139	Protein of unknown function (DUF1315)
YSA_RS04155	COG0705	Rhomboid family
YSA_RS04160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YSA_RS04165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YSA_RS04175	COG3038	cytochrome b561
YSA_RS04185	COG0446	pyridine nucleotide-disulphide oxidoreductase
YSA_RS04185	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS04190	COG2207	Transcriptional regulator
YSA_RS04200	COG0604	alcohol dehydrogenase
YSA_RS04205	COG4221	oxidoreductase activity
YSA_RS04225	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS04255	COG0784	Response regulator, receiver
YSA_RS04255	COG2205	protein histidine kinase activity
YSA_RS04260	COG2199	diguanylate cyclase activity
YSA_RS04260	COG2200	EAL domain
YSA_RS04260	COG2202	Pas domain
YSA_RS04265	COG0784	Response regulator, receiver
YSA_RS04265	COG2205	protein histidine kinase activity
YSA_RS04270	COG2197	response regulator
YSA_RS04340	COG1286	toxin biosynthetic process
YSA_RS04350	COG0285	dihydrofolate synthase activity
YSA_RS04355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YSA_RS04360	COG0135	phosphoribosylanthranilate isomerase activity
YSA_RS04390	COG0473	3-isopropylmalate dehydrogenase activity
YSA_RS04395	COG2226	methyltransferase
YSA_RS04400	COG0066	3-isopropylmalate dehydratase activity
YSA_RS04405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YSA_RS04425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YSA_RS04435	COG0596	Alpha beta hydrolase
YSA_RS04475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YSA_RS04490	COG0556	nucleotide-excision repair
YSA_RS04530	COG0084	hydrolase, TatD family'
YSA_RS04540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YSA_RS04545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YSA_RS04555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YSA_RS04560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YSA_RS04570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YSA_RS04575	COG0416	fatty acid biosynthetic process
YSA_RS04580	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YSA_RS04590	COG0424	maF-like protein
YSA_RS04595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YSA_RS04595	COG0616	signal peptide processing
YSA_RS04600	COG0546	phosphoglycolate phosphatase activity
YSA_RS04610	COG1530	ribonuclease E activity
YSA_RS04615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YSA_RS04620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YSA_RS04625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YSA_RS04630	COG2835	tetraacyldisaccharide 4'-kinase activity
YSA_RS04635	COG1663	tetraacyldisaccharide 4'-kinase activity
YSA_RS04640	COG0848	biopolymer transport protein
YSA_RS04645	COG0811	peptide transport
YSA_RS04655	COG0842	Transport permease protein
YSA_RS04660	COG1131	(ABC) transporter
YSA_RS04665	COG0625	glutathione transferase activity
YSA_RS04685	COG3121	Chaperone
YSA_RS04735	COG3188	usher protein
YSA_RS04775	COG1956	GAF domain-containing protein
YSA_RS04785	COG5002	protein histidine kinase activity
YSA_RS04785	COG0784	Response regulator, receiver
YSA_RS04785	COG2205	protein histidine kinase activity
YSA_RS04790	COG0386	Belongs to the glutathione peroxidase family
YSA_RS04795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YSA_RS04800	COG0436	Aminotransferase
YSA_RS04805	COG0501	Belongs to the peptidase M48B family
YSA_RS04810	COG0500	methyltransferase
YSA_RS04815	COG3384	dioxygenase
YSA_RS04830	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
YSA_RS04840	COG0583	DNA-binding transcription factor activity
YSA_RS04850	COG0583	DNA-binding transcription factor activity
YSA_RS04855	COG1846	Transcriptional regulator
YSA_RS04860	COG1764	response to oxidative stress
YSA_RS04865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YSA_RS04885	COG0583	DNA-binding transcription factor activity
YSA_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS04895	COG0583	DNA-binding transcription factor activity
YSA_RS04900	COG2814	Major facilitator Superfamily
YSA_RS04910	COG4773	Receptor
YSA_RS04930	COG0598	Magnesium transport protein CorA
YSA_RS04935	COG0519	Catalyzes the synthesis of GMP from XMP
YSA_RS04955	COG1368	sulfuric ester hydrolase activity
YSA_RS04985	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YSA_RS04990	COG2814	Major facilitator Superfamily
YSA_RS04995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YSA_RS05025	COG2840	Smr protein MutS2
YSA_RS05030	COG0302	gtp cyclohydrolase
YSA_RS05040	COG0625	glutathione transferase activity
YSA_RS05045	COG3135	benzoate transporter
YSA_RS05050	COG0840	transmembrane signaling receptor activity
YSA_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS05065	COG2130	NADP-dependent
YSA_RS05070	COG0284	orotidine-5'-phosphate decarboxylase activity
YSA_RS05075	COG1555	photosystem II stabilization
YSA_RS05095	COG0166	Belongs to the GPI family
YSA_RS05100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YSA_RS05105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YSA_RS05105	COG0517	IMP dehydrogenase activity
YSA_RS05115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YSA_RS05140	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YSA_RS05150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS05175	COG0438	transferase activity, transferring glycosyl groups
YSA_RS05175	COG1216	Glycosyl transferase, family 2
YSA_RS05185	COG0438	transferase activity, transferring glycosyl groups
YSA_RS05190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YSA_RS05225	COG0438	transferase activity, transferring glycosyl groups
YSA_RS05245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YSA_RS05250	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
YSA_RS05250	COG0662	Cupin 2, conserved barrel domain protein
YSA_RS05255	COG2755	lipolytic protein G-D-S-L family
YSA_RS05255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YSA_RS05260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YSA_RS05270	COG0776	regulation of translation
YSA_RS05280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YSA_RS05285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YSA_RS05295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YSA_RS05305	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YSA_RS05310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YSA_RS05315	COG0546	phosphoglycolate phosphatase activity
YSA_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS05330	COG5001	Diguanylate cyclase
YSA_RS05330	COG5002	protein histidine kinase activity
YSA_RS05345	COG1054	Belongs to the UPF0176 family
YSA_RS05350	COG0271	Belongs to the BolA IbaG family
YSA_RS05360	COG0114	fumarate hydratase activity
YSA_RS05365	COG0697	spore germination
YSA_RS05370	COG2326	polyphosphate kinase activity
YSA_RS05375	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YSA_RS05375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS05380	COG0367	asparagine synthase
YSA_RS05385	COG0189	ligase activity
YSA_RS05385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YSA_RS05390	COG1363	Peptidase, m42
YSA_RS05395	COG3089	Belongs to the UPF0270 family
YSA_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS05440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YSA_RS05445	COG3162	membrane
YSA_RS05450	COG2113	Glycine betaine
YSA_RS05470	COG2853	Lipoprotein
YSA_RS05480	COG1560	Kdo2-lipid A biosynthetic process
YSA_RS05485	COG0850	regulation of cytokinetic process
YSA_RS05490	COG2894	cell division
YSA_RS05495	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YSA_RS05500	COG0564	pseudouridine synthase activity
YSA_RS05505	COG1362	aminopeptidase activity
YSA_RS05510	COG0668	transmembrane transport
YSA_RS05530	COG1176	ABC-type spermidine putrescine transport system, permease component I
YSA_RS05560	COG3300	MHYT domain
YSA_RS05560	COG5001	Diguanylate cyclase
YSA_RS05575	COG3339	Conserved Protein
YSA_RS05580	COG0545	Peptidyl-prolyl cis-trans isomerase
YSA_RS05585	COG0583	DNA-binding transcription factor activity
YSA_RS05595	COG2169	Transcriptional regulator
YSA_RS05600	COG2271	Major facilitator Superfamily
YSA_RS05605	COG0179	Fumarylacetoacetate (FAA) hydrolase
YSA_RS05610	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS05615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YSA_RS05620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YSA_RS05620	COG2146	nitrite reductase [NAD(P)H] activity
YSA_RS05625	COG2146	nitrite reductase [NAD(P)H] activity
YSA_RS05625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YSA_RS05630	COG0243	molybdopterin cofactor binding
YSA_RS05635	COG0024	Methionine aminopeptidase
YSA_RS05660	COG2974	May be involved in recombination
YSA_RS05665	COG2076	Multidrug Resistance protein
YSA_RS05670	COG0477	Major facilitator Superfamily
YSA_RS05680	COG2814	Major facilitator Superfamily
YSA_RS05685	COG2188	Transcriptional regulator
YSA_RS05690	COG2814	Major facilitator Superfamily
YSA_RS05695	COG2205	protein histidine kinase activity
YSA_RS05725	COG0583	DNA-binding transcription factor activity
YSA_RS05745	COG1846	Transcriptional regulator
YSA_RS05755	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
YSA_RS05760	COG0406	alpha-ribazole phosphatase activity
YSA_RS05765	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YSA_RS05775	COG1492	cobalamin metabolic process
YSA_RS05785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YSA_RS05790	COG0778	Nitroreductase
YSA_RS05795	COG1797	cobyrinic acid a,c-diamide synthase activity
YSA_RS05805	COG0791	NLP P60 protein
YSA_RS05810	COG0791	NLP P60 protein
YSA_RS05820	COG0628	permease
YSA_RS05830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YSA_RS05835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YSA_RS05870	COG3122	Protein conserved in bacteria
YSA_RS05875	COG3956	TIGRFAM MazG family protein
YSA_RS05880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YSA_RS05885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YSA_RS05905	COG0784	Response regulator, receiver
YSA_RS05905	COG2205	protein histidine kinase activity
YSA_RS05905	COG5002	protein histidine kinase activity
YSA_RS05910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YSA_RS05950	COG0037	tRNA processing
YSA_RS05960	COG3091	SprT-like family
YSA_RS05970	COG0583	DNA-binding transcription factor activity
YSA_RS05985	COG3148	PFAM DTW domain containing protein
YSA_RS06005	COG2137	regulation of response to DNA damage stimulus
YSA_RS06010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YSA_RS06015	COG1546	Belongs to the CinA family
YSA_RS06025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YSA_RS06030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
YSA_RS06045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YSA_RS06050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YSA_RS06055	COG0585	pseudouridine synthase activity
YSA_RS06060	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YSA_RS06070	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
YSA_RS06080	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YSA_RS06090	COG0148	phosphopyruvate hydratase activity
YSA_RS06095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YSA_RS06100	COG0504	CTP synthase activity
YSA_RS06105	COG0037	tRNA processing
YSA_RS06110	COG0825	malonyl-CoA metabolic process
YSA_RS06120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YSA_RS06125	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YSA_RS06130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YSA_RS06135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YSA_RS06140	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YSA_RS06160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YSA_RS06170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YSA_RS06175	COG0233	cytoplasmic translational termination
YSA_RS06180	COG0528	UMP kinase activity
YSA_RS06185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YSA_RS06190	COG0052	Belongs to the universal ribosomal protein uS2 family
YSA_RS06195	COG0024	Methionine aminopeptidase
YSA_RS06200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YSA_RS06205	COG0436	Aminotransferase
YSA_RS06210	COG0025	NhaP-type Na H and K H
YSA_RS06215	COG1393	Belongs to the ArsC family
YSA_RS06220	COG2171	N-acyltransferase activity
YSA_RS06225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YSA_RS06235	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YSA_RS06240	COG1215	transferase activity, transferring glycosyl groups
YSA_RS06245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YSA_RS06250	COG2226	methyltransferase
YSA_RS06265	COG2937	Belongs to the GPAT DAPAT family
YSA_RS06285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS06295	COG0742	ribosomal rna small subunit methyltransferase
YSA_RS06330	COG0563	adenylate kinase activity
YSA_RS06335	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YSA_RS06350	COG2885	chlorophyll binding
YSA_RS06360	COG1073	alpha beta
YSA_RS06380	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YSA_RS06390	COG5001	Diguanylate cyclase
YSA_RS06390	COG4251	negative regulation of phosphorylation
YSA_RS06390	COG2203	Gaf domain
YSA_RS06390	COG3706	GGDEF domain
YSA_RS06395	COG2201	protein-glutamate methylesterase activity
YSA_RS06410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YSA_RS06410	COG0457	Tetratricopeptide repeat
YSA_RS06420	COG0840	transmembrane signaling receptor activity
YSA_RS06425	COG2979	Protein of unknown function (DUF533)
YSA_RS06430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YSA_RS06435	COG3842	ATPase activity
YSA_RS06440	COG1176	ABC-type spermidine putrescine transport system, permease component I
YSA_RS06445	COG1177	transmembrane transport
YSA_RS06450	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS06460	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS06475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YSA_RS06510	COG4974	Belongs to the 'phage' integrase family
YSA_RS06520	COG1607	acyl-coa hydrolase
YSA_RS06525	COG0335	large ribosomal subunit rRNA binding
YSA_RS06530	COG0336	Belongs to the RNA methyltransferase TrmD family
YSA_RS06535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YSA_RS06540	COG0228	four-way junction DNA binding
YSA_RS06545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YSA_RS06555	COG4536	flavin adenine dinucleotide binding
YSA_RS06560	COG0477	Major facilitator Superfamily
YSA_RS06565	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YSA_RS06585	COG0494	nUDIX hydrolase
YSA_RS06615	COG4628	conserved protein (DUF2132)
YSA_RS06620	COG4206	TonB-dependent receptor
YSA_RS06640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YSA_RS06650	COG2226	methyltransferase
YSA_RS06655	COG0500	methyltransferase
YSA_RS06675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YSA_RS06680	COG1381	Involved in DNA repair and RecF pathway recombination
YSA_RS06685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YSA_RS06690	COG0571	ribonuclease III activity
YSA_RS06695	COG0681	Belongs to the peptidase S26 family
YSA_RS06700	COG0481	GTPase activity
YSA_RS06705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YSA_RS06735	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YSA_RS06740	COG0354	folic acid binding
YSA_RS06780	COG3180	Ammonia monooxygenase
YSA_RS06790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YSA_RS06820	COG2267	carboxylic ester hydrolase activity
YSA_RS06855	COG4191	Histidine kinase
YSA_RS06865	COG0477	Major facilitator Superfamily
YSA_RS06895	COG2207	Transcriptional regulator
YSA_RS06905	COG0583	DNA-binding transcription factor activity
YSA_RS06910	COG2910	NAD(P)H-binding
YSA_RS06920	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
YSA_RS06925	COG0477	Major facilitator Superfamily
YSA_RS06930	COG1309	transcriptional regulator
YSA_RS06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS06960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YSA_RS06965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YSA_RS06970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YSA_RS06975	COG0477	Major facilitator Superfamily
YSA_RS06980	COG0183	Belongs to the thiolase family
YSA_RS06985	COG2814	Major facilitator Superfamily
YSA_RS06990	COG1414	Transcriptional regulator
YSA_RS07000	COG0306	phosphate transporter
YSA_RS07005	COG0433	COG0433 Predicted ATPase
YSA_RS07010	COG0840	transmembrane signaling receptor activity
YSA_RS07015	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YSA_RS07015	COG0438	transferase activity, transferring glycosyl groups
YSA_RS07030	COG0788	formyltetrahydrofolate deformylase activity
YSA_RS07040	COG2925	Exonuclease
YSA_RS07060	COG0459	protein refolding
YSA_RS07065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YSA_RS07070	COG3030	protein affecting phage T7 exclusion by the F plasmid
YSA_RS07100	COG0668	transmembrane transport
YSA_RS07105	COG1666	GTP binding
YSA_RS07120	COG2096	Adenosyltransferase
YSA_RS07125	COG0494	nUDIX hydrolase
YSA_RS07135	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
YSA_RS07140	COG0653	protein targeting
YSA_RS07150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
YSA_RS07155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YSA_RS07170	COG1181	Belongs to the D-alanine--D-alanine ligase family
YSA_RS07175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YSA_RS07180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YSA_RS07185	COG0772	Belongs to the SEDS family
YSA_RS07190	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
YSA_RS07195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YSA_RS07200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YSA_RS07205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YSA_RS07220	COG0275	rRNA processing
YSA_RS07225	COG2001	Belongs to the MraZ family
YSA_RS07240	COG0792	nuclease activity
YSA_RS07245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YSA_RS07250	COG2823	Periplasmic or secreted lipoprotein
YSA_RS07255	COG2969	positive regulation of protein catabolic process
YSA_RS07260	COG0625	glutathione transferase activity
YSA_RS07265	COG2857	Cytochrome c1
YSA_RS07270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YSA_RS07275	COG0723	plastoquinol--plastocyanin reductase activity
YSA_RS07280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YSA_RS07285	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YSA_RS07290	COG0667	Aldo Keto reductase
YSA_RS07300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YSA_RS07305	COG0180	Tryptophanyl-tRNA synthetase
YSA_RS07325	COG1522	sequence-specific DNA binding
YSA_RS07340	COG0175	sulfate reduction
YSA_RS07350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YSA_RS07355	COG1126	abc transporter atp-binding protein
YSA_RS07360	COG0765	amino acid transport
YSA_RS07365	COG4597	amino acid ABC transporter
YSA_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS07375	COG0400	carboxylic ester hydrolase activity
YSA_RS07380	COG0513	Belongs to the DEAD box helicase family
YSA_RS07390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YSA_RS07395	COG0315	cyclic pyranopterin monophosphate synthase activity
YSA_RS07400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
YSA_RS07410	COG3022	response to hydroperoxide
YSA_RS07415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YSA_RS07420	COG1215	transferase activity, transferring glycosyl groups
YSA_RS07425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS07430	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
YSA_RS07440	COG3420	alginic acid biosynthetic process
YSA_RS07455	COG1696	Membrane protein involved in D-alanine export
YSA_RS07470	COG0662	Cupin 2, conserved barrel domain protein
YSA_RS07470	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
YSA_RS07485	COG0300	oxidoreductase activity
YSA_RS07515	COG1566	PFAM secretion protein HlyD family protein
YSA_RS07535	COG0583	DNA-binding transcription factor activity
YSA_RS07540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YSA_RS07545	COG0697	spore germination
YSA_RS07550	COG3708	Transcriptional regulator
YSA_RS07550	COG2207	Transcriptional regulator
YSA_RS07630	COG0179	Fumarylacetoacetate (FAA) hydrolase
YSA_RS07635	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
YSA_RS07655	COG1346	cytolysis
YSA_RS07665	COG0583	DNA-binding transcription factor activity
YSA_RS07675	COG1366	Belongs to the anti-sigma-factor antagonist family
YSA_RS07715	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YSA_RS07725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YSA_RS07735	COG0523	cobalamin synthesis protein
YSA_RS07740	COG2879	small protein
YSA_RS07745	COG1966	Carbon starvation protein
YSA_RS07755	COG2233	PERMEase
YSA_RS07765	COG1970	mechanosensitive ion channel activity
YSA_RS07775	COG2197	response regulator
YSA_RS07780	COG2813	Specifically methylates the guanine in position
YSA_RS07790	COG1294	oxidase, subunit
YSA_RS07795	COG1271	oxidase subunit
YSA_RS07805	COG2252	PERMEase
YSA_RS07810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YSA_RS07815	COG3485	protocatechuate 3,4-dioxygenase
YSA_RS07820	COG3485	protocatechuate 3,4-dioxygenase
YSA_RS07825	COG2321	neutral zinc metallopeptidase
YSA_RS07830	COG0840	transmembrane signaling receptor activity
YSA_RS07840	COG0583	DNA-binding transcription factor activity
YSA_RS07845	COG2249	NAD(P)H dehydrogenase (quinone) activity
YSA_RS07895	COG2885	chlorophyll binding
YSA_RS07895	COG3047	cAMP biosynthetic process
YSA_RS07900	COG2199	diguanylate cyclase activity
YSA_RS07910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YSA_RS07915	COG1074	ATP-dependent DNA helicase activity
YSA_RS07920	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YSA_RS07950	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YSA_RS07955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YSA_RS07960	COG1183	phosphatidylcholine synthase activity
YSA_RS07965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YSA_RS07975	COG0028	Belongs to the TPP enzyme family
YSA_RS07980	COG3098	single-species biofilm formation
YSA_RS07990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YSA_RS08010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YSA_RS08015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YSA_RS08020	COG4558	Periplasmic binding protein
YSA_RS08030	COG1489	DNA binding
YSA_RS08035	COG0436	Aminotransferase
YSA_RS08045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YSA_RS08055	COG4191	Histidine kinase
YSA_RS08075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YSA_RS08080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YSA_RS08085	COG0166	Belongs to the GPI family
YSA_RS08090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YSA_RS08115	COG2823	Periplasmic or secreted lipoprotein
YSA_RS08120	COG1185	polyribonucleotide nucleotidyltransferase activity
YSA_RS08125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YSA_RS08130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YSA_RS08135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YSA_RS08140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YSA_RS08145	COG0195	Participates in both transcription termination and antitermination
YSA_RS08150	COG0779	Required for maturation of 30S ribosomal subunits
YSA_RS08165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YSA_RS08170	COG0149	triose-phosphate isomerase activity
YSA_RS08175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YSA_RS08180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YSA_RS08190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YSA_RS08205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YSA_RS08210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YSA_RS08215	COG0505	Belongs to the CarA family
YSA_RS08220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YSA_RS08225	COG0484	heat shock protein binding
YSA_RS08230	COG0443	Heat shock 70 kDa protein
YSA_RS08235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YSA_RS08240	COG0497	DNA recombination
YSA_RS08245	COG0735	belongs to the Fur family
YSA_RS08250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YSA_RS08260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YSA_RS08265	COG2186	Transcriptional regulator
YSA_RS08270	COG1620	l-lactate permease
YSA_RS08275	COG1304	FMN binding
YSA_RS08290	COG0582	viral genome integration into host DNA
YSA_RS08345	COG0789	Transcriptional regulator
YSA_RS08355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
YSA_RS08370	COG1280	lysine exporter protein (LysE YggA)
YSA_RS08375	COG3039	Transposase
YSA_RS08385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
YSA_RS08445	COG0840	transmembrane signaling receptor activity
YSA_RS08460	COG0582	viral genome integration into host DNA
YSA_RS08465	COG4983	Phage plasmid primase, P4 family domain protein
YSA_RS08510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YSA_RS08535	COG1401	restriction endodeoxyribonuclease activity
YSA_RS08555	COG4774	siderophore transport
YSA_RS08580	COG2271	Major facilitator Superfamily
YSA_RS08585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YSA_RS08590	COG0583	DNA-binding transcription factor activity
YSA_RS08610	COG3321	synthase
YSA_RS08610	COG0604	alcohol dehydrogenase
YSA_RS08615	COG0546	phosphoglycolate phosphatase activity
YSA_RS08620	COG1946	Acyl-CoA thioesterase
YSA_RS08630	COG0406	alpha-ribazole phosphatase activity
YSA_RS08635	COG0123	including yeast histone deacetylase and acetoin utilization protein
YSA_RS08645	COG0513	Belongs to the DEAD box helicase family
YSA_RS08650	COG0697	spore germination
YSA_RS08655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YSA_RS08665	COG3416	Protein conserved in bacteria
YSA_RS08680	COG1643	Atp-dependent helicase
YSA_RS08700	COG1522	sequence-specific DNA binding
YSA_RS08715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YSA_RS08720	COG1960	acyl-CoA dehydrogenase activity
YSA_RS08725	COG2205	protein histidine kinase activity
YSA_RS08725	COG3437	response regulator, receiver
YSA_RS08725	COG3850	Histidine kinase
YSA_RS08725	COG4999	Histidine kinase
YSA_RS08730	COG0351	phosphomethylpyrimidine kinase
YSA_RS08735	COG0352	thiamine-phosphate diphosphorylase activity
YSA_RS08740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YSA_RS08755	COG1702	phosphate starvation-inducible protein PhoH
YSA_RS08760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YSA_RS08765	COG4535	Mg2 and Co2 transporter CorC
YSA_RS08770	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YSA_RS08785	COG0495	leucyl-tRNA aminoacylation
YSA_RS08805	COG2951	lytic endotransglycosylase activity
YSA_RS08810	COG1619	proteins homologs of microcin C7 resistance protein MccF
YSA_RS08815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YSA_RS08820	COG0321	lipoyl(octanoyl) transferase activity
YSA_RS08825	COG2921	Belongs to the UPF0250 family
YSA_RS08830	COG1686	Belongs to the peptidase S11 family
YSA_RS08840	COG2951	lytic endotransglycosylase activity
YSA_RS08845	COG0772	Belongs to the SEDS family
YSA_RS08850	COG0768	penicillin binding
YSA_RS08855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
YSA_RS08865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YSA_RS08870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YSA_RS08880	COG2094	Belongs to the DNA glycosylase MPG family
YSA_RS08885	COG0586	Pfam SNARE associated Golgi protein
YSA_RS08895	COG1346	cytolysis
YSA_RS08910	COG2264	protein methyltransferase activity
YSA_RS08920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YSA_RS08930	COG0138	bifunctional purine biosynthesis protein purh
YSA_RS08935	COG0151	Belongs to the GarS family
YSA_RS08945	COG2095	MarC family integral membrane protein
YSA_RS08980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YSA_RS08990	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
YSA_RS09005	COG0330	HflC and HflK could
YSA_RS09025	COG4774	siderophore transport
YSA_RS09035	COG1113	amino acid transport
YSA_RS09055	COG0411	ABC transporter
YSA_RS09070	COG0789	Transcriptional regulator
YSA_RS09075	COG0484	heat shock protein binding
YSA_RS09080	COG0443	Heat shock 70 kDa protein
YSA_RS09100	COG0697	spore germination
YSA_RS09120	COG2982	Protein involved in outer membrane biogenesis
YSA_RS09145	COG4221	oxidoreductase activity
YSA_RS09175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YSA_RS09180	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YSA_RS09195	COG1032	radical SAM domain protein
YSA_RS09200	COG0305	Participates in initiation and elongation during chromosome replication
YSA_RS09205	COG0359	binds to the 23S rRNA
YSA_RS09215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YSA_RS09220	COG0360	Binds together with S18 to 16S ribosomal RNA
YSA_RS09225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YSA_RS09245	COG1840	ABC-type Fe3 transport system, periplasmic component
YSA_RS09250	COG1178	ABC-type Fe3 transport system permease component
YSA_RS09260	COG0840	transmembrane signaling receptor activity
YSA_RS09265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YSA_RS09270	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
YSA_RS09275	COG0330	HflC and HflK could
YSA_RS09280	COG0330	HflC and HflK could
YSA_RS09285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YSA_RS09290	COG1923	regulation of RNA biosynthetic process
YSA_RS09295	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YSA_RS09300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YSA_RS09305	COG0860	N-Acetylmuramoyl-L-alanine amidase
YSA_RS09310	COG0802	atpase or kinase
YSA_RS09315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YSA_RS09315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YSA_RS09325	COG2860	membrane
YSA_RS09330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YSA_RS09335	COG1162	GTPase activity
YSA_RS09345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YSA_RS09360	COG0688	phosphatidylethanolamine metabolic process
YSA_RS09365	COG3830	Belongs to the UPF0237 family
YSA_RS09365	COG0560	Phosphoserine phosphatase
YSA_RS09385	COG3577	Aspartyl protease
YSA_RS09400	COG3150	esterase
YSA_RS09405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YSA_RS09415	COG0494	nUDIX hydrolase
YSA_RS09430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YSA_RS09435	COG1538	Outer membrane efflux protein
YSA_RS09440	COG1519	Transferase
YSA_RS09445	COG0583	DNA-binding transcription factor activity
YSA_RS09460	COG0667	Aldo Keto reductase
YSA_RS09470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YSA_RS09470	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YSA_RS09475	COG1132	(ABC) transporter
YSA_RS09490	COG0438	transferase activity, transferring glycosyl groups
YSA_RS09515	COG0438	transferase activity, transferring glycosyl groups
YSA_RS09520	COG2192	nodulation
YSA_RS09525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YSA_RS09530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YSA_RS09535	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YSA_RS09535	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YSA_RS09535	COG0506	proline dehydrogenase activity
YSA_RS09545	COG1960	acyl-CoA dehydrogenase activity
YSA_RS09555	COG0312	modulator of DNA gyrase
YSA_RS09560	COG0477	Major facilitator Superfamily
YSA_RS09565	COG0513	Belongs to the DEAD box helicase family
YSA_RS09570	COG2081	HI0933 family
YSA_RS09575	COG1289	transmembrane transporter activity
YSA_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS09585	COG2153	protein acetylation
YSA_RS09595	COG1451	nucleotide metabolic process
YSA_RS09600	COG5001	Diguanylate cyclase
YSA_RS09600	COG3300	MHYT domain
YSA_RS09620	COG0126	phosphoglycerate kinase activity
YSA_RS09625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YSA_RS09630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YSA_RS09635	COG0640	Transcriptional regulator
YSA_RS09640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YSA_RS09645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YSA_RS09680	COG2801	Transposase and inactivated derivatives
YSA_RS09695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
YSA_RS09700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
YSA_RS09715	COG0513	Belongs to the DEAD box helicase family
YSA_RS09720	COG2353	YceI-like domain
YSA_RS09725	COG3038	cytochrome b561
YSA_RS09745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YSA_RS09750	COG1272	protein, Hemolysin III
YSA_RS09760	COG0643	Histidine kinase
YSA_RS09760	COG0784	Response regulator, receiver
YSA_RS09760	COG2198	Histidine kinase
YSA_RS09785	COG0189	ligase activity
YSA_RS09795	COG1678	Uncharacterized ACR, COG1678
YSA_RS09800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YSA_RS09805	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
YSA_RS09810	COG0540	Belongs to the ATCase OTCase family
YSA_RS09815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YSA_RS09820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YSA_RS09825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YSA_RS09875	COG2226	methyltransferase
YSA_RS09885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YSA_RS09890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YSA_RS09895	COG0140	phosphoribosyl-ATP diphosphatase activity
YSA_RS09900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YSA_RS09920	COG0840	transmembrane signaling receptor activity
YSA_RS09925	COG0840	transmembrane signaling receptor activity
YSA_RS09930	COG1126	abc transporter atp-binding protein
YSA_RS09935	COG0765	amino acid transport
YSA_RS09945	COG2943	transferase activity, transferring hexosyl groups
YSA_RS09950	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YSA_RS09955	COG1490	D-aminoacyl-tRNA deacylase activity
YSA_RS09970	COG1228	amidohydrolase
YSA_RS09980	COG2986	histidine ammonia-lyase
YSA_RS09985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YSA_RS09995	COG2188	Transcriptional regulator
YSA_RS10000	COG0402	S-adenosylhomocysteine deaminase activity
YSA_RS10025	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YSA_RS10030	COG0058	SHG alpha-glucan phosphorylase activity
YSA_RS10045	COG1217	gtp-binding protein TYPA
YSA_RS10050	COG0301	tRNA thio-modification
YSA_RS10050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YSA_RS10065	COG3852	Histidine kinase
YSA_RS10080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YSA_RS10085	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YSA_RS10095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YSA_RS10100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YSA_RS10105	COG4942	peptidase
YSA_RS10110	COG0793	Belongs to the peptidase S41A family
YSA_RS10115	COG2861	carbohydrate metabolic process
YSA_RS10125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YSA_RS10130	COG1309	transcriptional regulator
YSA_RS10135	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS10140	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
YSA_RS10150	COG3263	regulation of cellular component size
YSA_RS10155	COG1196	nuclear chromosome segregation
YSA_RS10155	COG3264	Mechanosensitive ion channel
YSA_RS10160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
YSA_RS10165	COG3118	belongs to the thioredoxin family
YSA_RS10170	COG1192	Involved in chromosome partitioning
YSA_RS10175	COG0583	DNA-binding transcription factor activity
YSA_RS10180	COG2814	Major facilitator Superfamily
YSA_RS10250	COG3397	chitin binding
YSA_RS10255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YSA_RS10260	COG0493	'glutamate synthase
YSA_RS10265	COG0067	glutamate synthase
YSA_RS10265	COG0069	glutamate synthase activity
YSA_RS10265	COG0070	glutamate synthase
YSA_RS10275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
YSA_RS10280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YSA_RS10310	COG0281	malic enzyme
YSA_RS10320	COG0254	rRNA binding
YSA_RS10325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YSA_RS10330	COG0018	arginyl-trna synthetase
YSA_RS10345	COG0791	NLP P60 protein
YSA_RS10370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YSA_RS10375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YSA_RS10375	COG2813	Specifically methylates the guanine in position
YSA_RS10385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YSA_RS10390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YSA_RS10400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YSA_RS10405	COG2022	thiamine diphosphate biosynthetic process
YSA_RS10415	COG2363	Small membrane protein
YSA_RS10420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YSA_RS10430	COG2177	Part of the ABC transporter FtsEX involved in
YSA_RS10435	COG2884	Cell division ATP-binding protein ftsE
YSA_RS10440	COG0552	protein localization to endoplasmic reticulum
YSA_RS10445	COG0612	Peptidase, M16
YSA_RS10450	COG0612	Peptidase, M16
YSA_RS10455	COG0742	ribosomal rna small subunit methyltransferase
YSA_RS10465	COG0612	Peptidase, M16
YSA_RS10495	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
YSA_RS10500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YSA_RS10505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YSA_RS10510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YSA_RS10520	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YSA_RS10525	COG0129	dihydroxy-acid dehydratase activity
YSA_RS10550	COG1823	symporter activity
YSA_RS10565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YSA_RS10570	COG1840	ABC-type Fe3 transport system, periplasmic component
YSA_RS10575	COG1178	ABC-type Fe3 transport system permease component
YSA_RS10580	COG3842	ATPase activity
YSA_RS10585	COG0583	DNA-binding transcription factor activity
YSA_RS10595	COG0789	Transcriptional regulator
YSA_RS10600	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YSA_RS10605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YSA_RS10610	COG0730	response to heat
YSA_RS10620	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
YSA_RS10625	COG0494	nUDIX hydrolase
YSA_RS10640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YSA_RS10645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YSA_RS10650	COG3204	pilus organization
YSA_RS10655	COG3204	pilus organization
YSA_RS10660	COG2801	Transposase and inactivated derivatives
YSA_RS10670	COG0179	Fumarylacetoacetate (FAA) hydrolase
YSA_RS10675	COG0277	FAD linked oxidase domain protein
YSA_RS10680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YSA_RS10735	COG3829	transcription factor binding
YSA_RS10745	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YSA_RS10750	COG4208	sulfate ABC transporter
YSA_RS10760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YSA_RS10770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YSA_RS10790	COG1177	transmembrane transport
YSA_RS10795	COG1176	ABC-type spermidine putrescine transport system, permease component I
YSA_RS10800	COG3842	ATPase activity
YSA_RS10820	COG0174	glutamine synthetase
YSA_RS10825	COG0174	glutamine synthetase
YSA_RS10830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YSA_RS10830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YSA_RS10835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YSA_RS10845	COG1522	sequence-specific DNA binding
YSA_RS10865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YSA_RS10865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YSA_RS10870	COG0509	glycine decarboxylation via glycine cleavage system
YSA_RS10875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YSA_RS10880	COG1178	ABC-type Fe3 transport system permease component
YSA_RS10890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YSA_RS10900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YSA_RS10905	COG0006	proline dipeptidase activity
YSA_RS10910	COG3079	Belongs to the UPF0149 family
YSA_RS10925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YSA_RS10935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS10940	COG0842	Transport permease protein
YSA_RS10940	COG1129	ABC transporter
YSA_RS10945	COG0842	Transport permease protein
YSA_RS10970	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YSA_RS10985	COG0248	Ppx GppA phosphatase
YSA_RS10990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YSA_RS11005	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YSA_RS11010	COG1671	Belongs to the UPF0178 family
YSA_RS11020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YSA_RS11030	COG1965	Belongs to the frataxin family
YSA_RS11040	COG0019	diaminopimelate decarboxylase activity
YSA_RS11045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YSA_RS11055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YSA_RS11060	COG0546	phosphoglycolate phosphatase activity
YSA_RS11070	COG0004	ammonium transporteR
YSA_RS11075	COG0347	Belongs to the P(II) protein family
YSA_RS11095	COG0606	chelatase, subunit chli
YSA_RS11105	COG4566	intracellular signal transduction
YSA_RS11110	COG4191	Histidine kinase
YSA_RS11115	COG1335	isochorismatase
YSA_RS11140	COG1335	isochorismatase
YSA_RS11145	COG0583	DNA-binding transcription factor activity
YSA_RS11175	COG1335	isochorismatase
YSA_RS11185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS11190	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS11195	COG0583	DNA-binding transcription factor activity
YSA_RS11200	COG5383	Protein conserved in bacteria
YSA_RS11210	COG0534	Mate efflux family protein
YSA_RS11225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YSA_RS11230	COG0427	acetyl-CoA hydrolase
YSA_RS11245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YSA_RS11250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS11275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS11280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YSA_RS11290	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS11305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YSA_RS11310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YSA_RS11315	COG0747	negative chemotaxis
YSA_RS11355	COG2433	Pfam Transposase IS66
YSA_RS11370	COG1288	antiporter activity
YSA_RS11385	COG2194	sulfuric ester hydrolase activity
YSA_RS11435	COG0463	Glycosyl transferase, family 2
YSA_RS11525	COG2003	Belongs to the UPF0758 family
YSA_RS11530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YSA_RS11535	COG0756	dUTP diphosphatase activity
YSA_RS11540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YSA_RS11545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YSA_RS11550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YSA_RS11555	COG0708	Exodeoxyribonuclease III
YSA_RS11565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YSA_RS11570	COG1561	YicC-like family, N-terminal region
YSA_RS11575	COG0194	GDP metabolic process
YSA_RS11590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
YSA_RS11595	COG0174	glutamine synthetase
YSA_RS11605	COG1758	RNA polymerase activity
YSA_RS11610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YSA_RS11635	COG0848	biopolymer transport protein
YSA_RS11645	COG0583	DNA-binding transcription factor activity
YSA_RS11650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YSA_RS11680	COG3161	chorismate lyase activity
YSA_RS11685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YSA_RS11705	COG1253	flavin adenine dinucleotide binding
YSA_RS11710	COG0739	heme binding
YSA_RS11720	COG0704	Plays a role in the regulation of phosphate uptake
YSA_RS11725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YSA_RS11730	COG0581	inorganic phosphate transmembrane transporter activity
YSA_RS11745	COG0477	Major facilitator Superfamily
YSA_RS11750	COG1607	acyl-coa hydrolase
YSA_RS11785	COG0583	DNA-binding transcription factor activity
YSA_RS11790	COG1027	Aspartate ammonia-lyase
YSA_RS11830	COG5016	pyruvate
YSA_RS11830	COG0511	ligase activity, forming carbon-carbon bonds
YSA_RS11835	COG0439	Biotin carboxylase
YSA_RS11840	COG0583	DNA-binding transcription factor activity
YSA_RS11850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YSA_RS11855	COG0210	DNA helicase
YSA_RS11870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YSA_RS11870	COG4651	solute:proton antiporter activity
YSA_RS11875	COG1607	acyl-coa hydrolase
YSA_RS11880	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
YSA_RS11890	COG0523	cobalamin synthesis protein
YSA_RS11915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YSA_RS11920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YSA_RS11925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YSA_RS11930	COG3958	Transketolase
YSA_RS11935	COG3959	Transketolase, thiamine diphosphate binding domain
YSA_RS11940	COG2271	Major facilitator Superfamily
YSA_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS11950	COG0583	DNA-binding transcription factor activity
YSA_RS12005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YSA_RS12010	COG1349	DNA-binding transcription factor activity
YSA_RS12015	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YSA_RS12020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YSA_RS12025	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YSA_RS12030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YSA_RS12035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YSA_RS12040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YSA_RS12045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YSA_RS12055	COG0356	it plays a direct role in the translocation of protons across the membrane
YSA_RS12060	COG3312	ion transport
YSA_RS12065	COG1475	DNA binding
YSA_RS12070	COG1192	Involved in chromosome partitioning
YSA_RS12075	COG0357	Ribosomal RNA small subunit methyltransferase G
YSA_RS12080	COG0445	tRNA wobble uridine modification
YSA_RS12085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YSA_RS12090	COG0706	membrane insertase activity
YSA_RS12095	COG0594	ribonuclease P activity
YSA_RS12100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YSA_RS12105	COG0592	DNA-directed DNA polymerase activity
YSA_RS12110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YSA_RS12115	COG0187	DNA topoisomerase II activity
YSA_RS12155	COG0477	Major facilitator Superfamily
YSA_RS12165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YSA_RS12170	COG0751	glycine-tRNA ligase activity
YSA_RS12175	COG0752	glycyl-tRNA synthetase alpha subunit
YSA_RS12180	COG2818	Glycosylase
YSA_RS12195	COG0569	domain protein
YSA_RS12200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YSA_RS12205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YSA_RS12210	COG0242	peptide deformylase activity
YSA_RS12215	COG0758	DNA mediated transformation
YSA_RS12220	COG0009	L-threonylcarbamoyladenylate synthase
YSA_RS12235	COG0408	coproporphyrinogen oxidase activity
YSA_RS12240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YSA_RS12245	COG0659	secondary active sulfate transmembrane transporter activity
YSA_RS12255	COG3119	arylsulfatase activity
YSA_RS12275	COG0159	tryptophan synthase activity
YSA_RS12280	COG0133	tryptophan synthase activity
YSA_RS12295	COG3360	Dodecin
YSA_RS12305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YSA_RS12310	COG1764	response to oxidative stress
YSA_RS12340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YSA_RS12345	COG0339	signal peptide processing
YSA_RS12350	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YSA_RS12370	COG0659	secondary active sulfate transmembrane transporter activity
YSA_RS12380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YSA_RS12385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YSA_RS12390	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
YSA_RS12415	COG1612	heme a metabolic process
YSA_RS12420	COG0109	protoheme IX farnesyltransferase activity
YSA_RS12435	COG2011	ABC-type metal ion transport system permease component
YSA_RS12440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YSA_RS12455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YSA_RS12460	COG1121	(ABC) transporter
YSA_RS12465	COG0735	belongs to the Fur family
YSA_RS12470	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YSA_RS12490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YSA_RS12495	COG3245	cytochrome
YSA_RS12505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YSA_RS12520	COG3023	N-Acetylmuramoyl-L-alanine amidase
YSA_RS12525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
YSA_RS12530	COG5002	protein histidine kinase activity
YSA_RS12535	COG2204	response regulator
YSA_RS12560	COG1301	dicarboxylic acid transport
YSA_RS12565	COG0700	Nucleoside recognition
YSA_RS12580	COG1127	ABC transporter
YSA_RS12585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YSA_RS12600	COG1283	sodium-dependent phosphate transmembrane transporter activity
YSA_RS12605	COG0861	Integral membrane protein TerC family
YSA_RS12610	COG2851	Citrate transporter
YSA_RS12645	COG0427	acetyl-CoA hydrolase
YSA_RS12665	COG0583	DNA-binding transcription factor activity
YSA_RS12670	COG1960	acyl-CoA dehydrogenase activity
YSA_RS12715	COG1802	Transcriptional regulator
YSA_RS12725	COG5001	Diguanylate cyclase
YSA_RS12725	COG3300	MHYT domain
YSA_RS12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS12750	COG2175	clavaminate synthase activity
YSA_RS12765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YSA_RS12785	COG1289	transmembrane transporter activity
YSA_RS12795	COG1566	PFAM secretion protein HlyD family protein
YSA_RS12805	COG0672	)-iron permease
YSA_RS12820	COG0625	glutathione transferase activity
YSA_RS12825	COG0165	Argininosuccinate lyase
YSA_RS12835	COG0181	hydroxymethylbilane synthase activity
YSA_RS12855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YSA_RS12880	COG0488	(ABC) transporter
YSA_RS12890	COG1280	lysine exporter protein (LysE YggA)
YSA_RS12920	COG0517	IMP dehydrogenase activity
YSA_RS12920	COG0516	GMP reductase activity
YSA_RS12935	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS12940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YSA_RS12950	COG2199	diguanylate cyclase activity
YSA_RS12965	COG2011	ABC-type metal ion transport system permease component
YSA_RS12970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YSA_RS12975	COG1464	Belongs to the NlpA lipoprotein family
YSA_RS12995	COG1126	abc transporter atp-binding protein
YSA_RS13000	COG0765	amino acid transport
YSA_RS13005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS13010	COG1045	serine acetyltransferase
YSA_RS13015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YSA_RS13020	COG2175	clavaminate synthase activity
YSA_RS13025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YSA_RS13030	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
YSA_RS13035	COG4521	taurine ABC transporter
YSA_RS13045	COG0450	alkyl hydroperoxide reductase
YSA_RS13050	COG0431	NADPH-dependent FMN reductase
YSA_RS13055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YSA_RS13060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YSA_RS13065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YSA_RS13070	COG1116	anion transmembrane transporter activity
YSA_RS13085	COG2918	glutathione biosynthetic process
YSA_RS13095	COG2183	response to ionizing radiation
YSA_RS13110	COG0189	ligase activity
YSA_RS13115	COG4067	protein conserved in archaea
YSA_RS13115	COG0189	ligase activity
YSA_RS13120	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YSA_RS13130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
YSA_RS13135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YSA_RS13155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YSA_RS13160	COG1652	LysM domain
YSA_RS13165	COG1011	Hydrolase
YSA_RS13170	COG0494	nUDIX hydrolase
YSA_RS13200	COG2957	Belongs to the agmatine deiminase family
YSA_RS13215	COG0069	glutamate synthase activity
YSA_RS13270	COG4695	Portal protein
YSA_RS13325	COG4215	(ABC) transporter
YSA_RS13360	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YSA_RS13375	COG2223	nitrite transmembrane transporter activity
YSA_RS13380	COG0131	Imidazoleglycerol-phosphate dehydratase
YSA_RS13385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YSA_RS13395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YSA_RS13400	COG0107	imidazoleglycerol-phosphate synthase activity
YSA_RS13405	COG4175	Glycine betaine
YSA_RS13410	COG4176	ABC-type proline glycine betaine transport system permease component
YSA_RS13420	COG1760	l-serine dehydratase
YSA_RS13435	COG3291	Pkd domain containing protein
YSA_RS13445	COG1250	3-hydroxyacyl-CoA dehydrogenase
YSA_RS13450	COG3246	L-lysine catabolic process to acetate
YSA_RS13490	COG0446	pyridine nucleotide-disulphide oxidoreductase
YSA_RS13490	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS13495	COG0247	lactate metabolic process
YSA_RS13495	COG2181	nitrate reductase activity
YSA_RS13500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
YSA_RS13515	COG4638	Rieske (2fe-2S)
YSA_RS13520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YSA_RS13520	COG1017	nitric oxide dioxygenase activity
YSA_RS13545	COG0840	transmembrane signaling receptor activity
YSA_RS13555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YSA_RS13585	COG1063	alcohol dehydrogenase
YSA_RS13595	COG0204	Acyl-transferase
YSA_RS13605	COG0745	RESPONSE REGULATOR receiver
YSA_RS13610	COG2205	protein histidine kinase activity
YSA_RS13615	COG4452	Inner membrane protein CreD
YSA_RS13625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YSA_RS13645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YSA_RS13660	COG0438	transferase activity, transferring glycosyl groups
YSA_RS13700	COG4774	siderophore transport
YSA_RS13705	COG3712	iron ion homeostasis
YSA_RS13710	COG1595	DNA-templated transcription, initiation
YSA_RS13715	COG2176	DNA-directed DNA polymerase activity
YSA_RS13720	COG0516	GMP reductase activity
YSA_RS13720	COG0517	IMP dehydrogenase activity
YSA_RS13725	COG2204	response regulator
YSA_RS13730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YSA_RS13745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YSA_RS13750	COG3585	molybdate ion transport
YSA_RS13750	COG2005	Transcriptional regulator
YSA_RS13755	COG1040	competence protein
YSA_RS13760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YSA_RS13765	COG0156	8-amino-7-oxononanoate synthase activity
YSA_RS13790	COG1960	acyl-CoA dehydrogenase activity
YSA_RS13795	COG3706	GGDEF domain
YSA_RS13800	COG1960	acyl-CoA dehydrogenase activity
YSA_RS13805	COG0583	DNA-binding transcription factor activity
YSA_RS13810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YSA_RS13825	COG0535	radical SAM domain protein
YSA_RS13835	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
YSA_RS13840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YSA_RS13845	COG1025	Belongs to the peptidase M16 family
YSA_RS13850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YSA_RS13885	COG0358	DNA primase activity
YSA_RS13890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YSA_RS13895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YSA_RS13900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YSA_RS13905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YSA_RS13915	COG0617	tRNA 3'-terminal CCA addition
YSA_RS13920	COG2719	SpoVR family
YSA_RS13925	COG2718	Belongs to the UPF0229 family
YSA_RS13930	COG2766	serine protein kinase
YSA_RS13935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YSA_RS13940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YSA_RS13945	COG2967	ApaG domain
YSA_RS13950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YSA_RS13955	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YSA_RS13960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YSA_RS13965	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YSA_RS13970	COG3178	'Phosphotransferase
YSA_RS13975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YSA_RS13990	COG4585	Histidine kinase
YSA_RS13995	COG2197	response regulator
YSA_RS14000	COG3842	ATPase activity
YSA_RS14010	COG1176	ABC-type spermidine putrescine transport system, permease component I
YSA_RS14020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YSA_RS14025	COG0546	phosphoglycolate phosphatase activity
YSA_RS14030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
YSA_RS14035	COG3240	lipase activity
YSA_RS14035	COG4625	pathogenesis
YSA_RS14040	COG0512	Glutamine amidotransferase of anthranilate synthase
YSA_RS14045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YSA_RS14050	COG0134	indole-3-glycerol-phosphate synthase activity
YSA_RS14065	COG1765	OsmC-like protein
YSA_RS14075	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
YSA_RS14080	COG0537	adenosine 5'-monophosphoramidase activity
YSA_RS14085	COG0300	oxidoreductase activity
YSA_RS14095	COG1981	membrane
YSA_RS14100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YSA_RS14105	COG0316	Belongs to the HesB IscA family
YSA_RS14110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YSA_RS14115	COG0739	heme binding
YSA_RS14120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YSA_RS14150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YSA_RS14150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YSA_RS14155	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
YSA_RS14180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YSA_RS14200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YSA_RS14205	COG0081	regulation of translation
YSA_RS14210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YSA_RS14215	COG0222	ribosome binding
YSA_RS14220	COG0085	RNA polymerase activity
YSA_RS14225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YSA_RS14230	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YSA_RS14235	COG0049	tRNA binding
YSA_RS14240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YSA_RS14245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YSA_RS14250	COG0051	transcription antitermination factor activity, RNA binding
YSA_RS14255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YSA_RS14260	COG0088	Forms part of the polypeptide exit tunnel
YSA_RS14265	COG0089	rRNA binding
YSA_RS14270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YSA_RS14275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YSA_RS14280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YSA_RS14285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YSA_RS14290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YSA_RS14295	COG0255	Belongs to the universal ribosomal protein uL29 family
YSA_RS14300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YSA_RS14305	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YSA_RS14310	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YSA_RS14315	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YSA_RS14320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YSA_RS14325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YSA_RS14330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YSA_RS14335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YSA_RS14340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YSA_RS14345	COG1841	ribosomal large subunit assembly
YSA_RS14350	COG0200	Binds to the 23S rRNA
YSA_RS14360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YSA_RS14365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YSA_RS14370	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YSA_RS14375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YSA_RS14380	COG0202	RNA polymerase activity
YSA_RS14385	COG0203	ribosomal protein L17
YSA_RS14390	COG0753	catalase activity
YSA_RS14395	COG2193	ferroxidase activity
YSA_RS14400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YSA_RS14405	COG2814	Major facilitator Superfamily
YSA_RS14410	COG0629	single-stranded DNA binding
YSA_RS14415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS14425	COG4221	oxidoreductase activity
YSA_RS14430	COG0243	molybdopterin cofactor binding
YSA_RS14430	COG3383	formate dehydrogenase (NAD+) activity
YSA_RS14435	COG0243	molybdopterin cofactor binding
YSA_RS14435	COG3383	formate dehydrogenase (NAD+) activity
YSA_RS14440	COG0437	4 iron, 4 sulfur cluster binding
YSA_RS14445	COG2864	formate dehydrogenase
YSA_RS14450	COG3058	Necessary for formate dehydrogenase activity
YSA_RS14455	COG1921	L-seryl-tRNASec selenium transferase activity
YSA_RS14460	COG3276	selenocysteine insertion sequence binding
YSA_RS14470	COG0252	asparaginase activity
YSA_RS14475	COG1115	amino acid carrier protein
YSA_RS14510	COG2814	Major facilitator Superfamily
YSA_RS14515	COG3047	cAMP biosynthetic process
YSA_RS14530	COG0577	efflux transmembrane transporter activity
YSA_RS14530	COG1136	(ABC) transporter
YSA_RS14545	COG3118	belongs to the thioredoxin family
YSA_RS14550	COG2264	protein methyltransferase activity
YSA_RS14560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YSA_RS14565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YSA_RS14565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YSA_RS14580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YSA_RS14585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YSA_RS14590	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YSA_RS14595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YSA_RS14605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YSA_RS14615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YSA_RS14620	COG4206	TonB-dependent receptor
YSA_RS14625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YSA_RS14630	COG0142	geranyltranstransferase activity
YSA_RS14635	COG1722	exodeoxyribonuclease VII activity
YSA_RS14640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YSA_RS14650	COG2819	hydrolase of the alpha beta superfamily
YSA_RS14700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YSA_RS14705	COG3228	Belongs to the MtfA family
YSA_RS14710	COG0586	Pfam SNARE associated Golgi protein
YSA_RS14715	COG0456	acetyltransferase
YSA_RS14720	COG4302	ethanolamine ammonia-lyase activity
YSA_RS14725	COG4303	Ethanolamine ammonia lyase large subunit
YSA_RS14730	COG0531	amino acid
YSA_RS14740	COG3284	Transcriptional regulator
YSA_RS14745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YSA_RS14760	COG0702	epimerase
YSA_RS14770	COG1063	alcohol dehydrogenase
YSA_RS14780	COG0022	dehydrogenase e1 component
YSA_RS14785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YSA_RS14790	COG3199	ATP-NAD kinase
YSA_RS14795	COG3284	Transcriptional regulator
YSA_RS14810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YSA_RS14840	COG0023	Translation Initiation Factor
YSA_RS14845	COG1166	arginine decarboxylase activity
YSA_RS14855	COG0534	Mate efflux family protein
YSA_RS14860	COG2373	Large extracellular alpha-helical protein
YSA_RS14870	COG4953	penicillin-binding protein 1C
YSA_RS14900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YSA_RS14910	COG2030	dehydratase
YSA_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS14925	COG2207	Transcriptional regulator
YSA_RS14930	COG0840	transmembrane signaling receptor activity
YSA_RS14940	COG2217	Heavy metal translocating P-type atpase
YSA_RS14955	COG2814	Major facilitator Superfamily
YSA_RS14965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YSA_RS14975	COG1739	Uncharacterized protein family UPF0029
YSA_RS14980	COG1309	transcriptional regulator
YSA_RS15015	COG2995	paraquat-inducible protein a
YSA_RS15020	COG2995	paraquat-inducible protein a
YSA_RS15025	COG3008	intermembrane lipid transfer
YSA_RS15030	COG0268	Binds directly to 16S ribosomal RNA
YSA_RS15040	COG0196	riboflavin kinase activity
YSA_RS15045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YSA_RS15050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YSA_RS15055	COG1047	Peptidyl-prolyl cis-trans
YSA_RS15060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YSA_RS15090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS15115	COG1172	Belongs to the binding-protein-dependent transport system permease family
YSA_RS15155	COG0542	response to heat
YSA_RS15185	COG1252	NADH dehydrogenase
YSA_RS15210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YSA_RS15215	COG0237	dephospho-CoA kinase activity
YSA_RS15245	COG1278	Cold shock
YSA_RS15325	COG0039	L-malate dehydrogenase activity
YSA_RS15330	COG0765	amino acid transport
YSA_RS15335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS15340	COG0646	methionine synthase
YSA_RS15340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
YSA_RS15345	COG0626	cystathionine gamma-synthase activity
YSA_RS15350	COG0833	amino acid
YSA_RS15355	COG0583	DNA-binding transcription factor activity
YSA_RS15375	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS15390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YSA_RS15405	COG0488	(ABC) transporter
YSA_RS15410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YSA_RS15415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YSA_RS15435	COG1067	ATP-dependent peptidase activity
YSA_RS15445	COG2862	Uncharacterized protein family, UPF0114
YSA_RS15455	COG0545	Peptidyl-prolyl cis-trans isomerase
YSA_RS15460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YSA_RS15465	COG2824	Alkylphosphonate utilization operon protein PhnA
YSA_RS15470	COG0142	geranyltranstransferase activity
YSA_RS15475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YSA_RS15480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YSA_RS15485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YSA_RS15490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YSA_RS15495	COG3045	CreA protein
YSA_RS15520	COG0456	acetyltransferase
YSA_RS15550	COG2223	nitrite transmembrane transporter activity
YSA_RS15560	COG3712	iron ion homeostasis
YSA_RS15565	COG1595	DNA-templated transcription, initiation
YSA_RS15575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YSA_RS15575	COG2169	Transcriptional regulator
YSA_RS15580	COG1511	domain protein
YSA_RS15580	COG3264	Mechanosensitive ion channel
YSA_RS15605	COG1335	isochorismatase
YSA_RS15620	COG0628	permease
YSA_RS15650	COG0193	aminoacyl-tRNA hydrolase activity
YSA_RS15655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YSA_RS15660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YSA_RS15670	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
YSA_RS15675	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
YSA_RS15700	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YSA_RS15705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YSA_RS15715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YSA_RS15720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YSA_RS15735	COG0415	Belongs to the DNA photolyase family
YSA_RS15740	COG0789	Transcriptional regulator
YSA_RS15750	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
YSA_RS15755	COG1090	epimerase
YSA_RS15760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YSA_RS15770	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YSA_RS15775	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YSA_RS15795	COG0579	oxidoreductase
YSA_RS15835	COG2135	peptidase activity
YSA_RS15845	COG2119	membrane
YSA_RS15850	COG2813	Specifically methylates the guanine in position
YSA_RS15855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YSA_RS15860	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS15900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YSA_RS15905	COG2885	chlorophyll binding
YSA_RS15910	COG0280	phosphate acetyltransferase
YSA_RS15910	COG0857	belongs to the CobB CobQ family
YSA_RS15925	COG0386	Belongs to the glutathione peroxidase family
YSA_RS15955	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YSA_RS15960	COG0492	ferredoxin-NADP+ reductase activity
YSA_RS15975	COG3023	N-Acetylmuramoyl-L-alanine amidase
YSA_RS15985	COG0084	hydrolase, TatD family'
YSA_RS15990	COG1609	Transcriptional regulator
YSA_RS16000	COG1105	Belongs to the carbohydrate kinase PfkB family
YSA_RS16005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YSA_RS16005	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YSA_RS16005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YSA_RS16010	COG3530	Putative quorum-sensing-regulated virulence factor
YSA_RS16020	COG3706	GGDEF domain
YSA_RS16020	COG4251	negative regulation of phosphorylation
YSA_RS16020	COG2203	Gaf domain
YSA_RS16020	COG5001	Diguanylate cyclase
YSA_RS16070	COG3604	Transcriptional regulator
YSA_RS16075	COG1017	nitric oxide dioxygenase activity
YSA_RS16075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YSA_RS16080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YSA_RS16085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YSA_RS16090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YSA_RS16095	COG1845	cytochrome c oxidase, subunit III
YSA_RS16100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YSA_RS16105	COG0109	protoheme IX farnesyltransferase activity
YSA_RS16110	COG0436	Aminotransferase
YSA_RS16120	COG0727	PFAM Uncharacterised protein family (UPF0153)
YSA_RS16130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YSA_RS16135	COG1595	DNA-templated transcription, initiation
YSA_RS16160	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YSA_RS16165	COG0709	Synthesizes selenophosphate from selenide and ATP
YSA_RS16170	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YSA_RS16175	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YSA_RS16180	COG3639	organic phosphonate transmembrane transporter activity
YSA_RS16185	COG3639	organic phosphonate transmembrane transporter activity
YSA_RS16190	COG3781	membrane
YSA_RS16195	COG3657	addiction module killer protein
YSA_RS16235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YSA_RS16240	COG0343	queuine tRNA-ribosyltransferase activity
YSA_RS16245	COG1862	Preprotein translocase
YSA_RS16260	COG3134	Outer membrane lipoprotein
YSA_RS16280	COG1045	serine acetyltransferase
YSA_RS16290	COG1104	cysteine desulfurase activity
YSA_RS16300	COG0316	Belongs to the HesB IscA family
YSA_RS16305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YSA_RS16310	COG0443	Heat shock 70 kDa protein
YSA_RS16315	COG0633	Ferredoxin
YSA_RS16325	COG0105	UTP biosynthetic process
YSA_RS16330	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YSA_RS16345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YSA_RS16350	COG0124	histidyl-tRNA synthetase
YSA_RS16365	COG1160	GTP binding
YSA_RS16370	COG0436	Aminotransferase
YSA_RS16380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YSA_RS16385	COG4774	siderophore transport
YSA_RS16390	COG3128	pkhd-type hydroxylase
YSA_RS16400	COG0019	diaminopimelate decarboxylase activity
YSA_RS16405	COG1595	DNA-templated transcription, initiation
YSA_RS16415	COG4772	TonB-dependent receptor
YSA_RS16440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YSA_RS16455	COG0723	plastoquinol--plastocyanin reductase activity
YSA_RS16455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS16480	COG4608	Belongs to the ABC transporter superfamily
YSA_RS16485	COG0444	Belongs to the ABC transporter superfamily
YSA_RS16490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YSA_RS16495	COG0601	transmembrane transport
YSA_RS16500	COG0747	negative chemotaxis
YSA_RS16510	COG0747	negative chemotaxis
YSA_RS16515	COG0747	negative chemotaxis
YSA_RS16530	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
YSA_RS16550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YSA_RS16555	COG0693	protein deglycase activity
YSA_RS16570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YSA_RS16570	COG3153	acetyltransferase
YSA_RS16600	COG0642	Histidine kinase
YSA_RS16610	COG3642	lipopolysaccharide core region biosynthetic process
YSA_RS16620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YSA_RS16625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS16665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YSA_RS16675	COG0583	DNA-binding transcription factor activity
YSA_RS16680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YSA_RS16690	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS16725	COG1113	amino acid transport
YSA_RS16740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YSA_RS16745	COG0154	amidase activity
YSA_RS16750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YSA_RS16755	COG1077	Cell shape determining protein MreB Mrl
YSA_RS16760	COG1792	Involved in formation and maintenance of cell shape
YSA_RS16770	COG0424	maF-like protein
YSA_RS16785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YSA_RS16790	COG0312	modulator of DNA gyrase
YSA_RS16795	COG3028	Belongs to the UPF0307 family
YSA_RS16800	COG0312	modulator of DNA gyrase
YSA_RS16830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YSA_RS16835	COG1660	Displays ATPase and GTPase activities
YSA_RS16845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YSA_RS16850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YSA_RS16855	COG1137	ATPase activity
YSA_RS16860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YSA_RS16870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YSA_RS16880	COG1127	ABC transporter
YSA_RS16885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YSA_RS16890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YSA_RS16910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YSA_RS16915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YSA_RS16920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YSA_RS16925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YSA_RS16935	COG2186	Transcriptional regulator
YSA_RS16940	COG2807	transmembrane transport
YSA_RS16950	COG2827	Endonuclease containing a URI domain
YSA_RS16955	COG3081	Nucleoid-associated protein
YSA_RS16960	COG0776	regulation of translation
YSA_RS16965	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
YSA_RS16970	COG0525	valine-tRNA ligase activity
YSA_RS16985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YSA_RS16995	COG0795	lipopolysaccharide-transporting ATPase activity
YSA_RS17000	COG0795	lipopolysaccharide-transporting ATPase activity
YSA_RS17010	COG1278	Cold shock
YSA_RS17015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YSA_RS17020	COG1760	l-serine dehydratase
YSA_RS17025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YSA_RS17025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YSA_RS17030	COG0509	glycine decarboxylation via glycine cleavage system
YSA_RS17045	COG3220	belongs to the UPF0276 family
YSA_RS17055	COG1595	DNA-templated transcription, initiation
YSA_RS17060	COG4944	Protein of unknown function (DUF1109)
YSA_RS17065	COG0786	glutamate:sodium symporter activity
YSA_RS17085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YSA_RS17090	COG2235	arginine
YSA_RS17105	COG2832	Protein of unknown function (DUF454)
YSA_RS17160	COG1653	transport
YSA_RS17165	COG1175	transmembrane transport
YSA_RS17175	COG3842	ATPase activity
YSA_RS17185	COG0676	glucose-6-phosphate 1-epimerase activity
YSA_RS17190	COG1737	Transcriptional regulator
YSA_RS17205	COG0800	Aldolase
YSA_RS17220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YSA_RS17225	COG0739	heme binding
YSA_RS17230	COG1570	exodeoxyribonuclease VII activity
YSA_RS17235	COG0583	DNA-binding transcription factor activity
YSA_RS17255	COG0519	Catalyzes the synthesis of GMP from XMP
YSA_RS17255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YSA_RS17260	COG1397	ADP-ribosylglycohydrolase
YSA_RS17265	COG2369	cell adhesion
YSA_RS17275	COG0590	tRNA wobble adenosine to inosine editing
YSA_RS17280	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YSA_RS17285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
YSA_RS17285	COG0047	phosphoribosylformylglycinamidine synthase activity
YSA_RS17300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YSA_RS17305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YSA_RS17335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YSA_RS17380	COG2375	cellular response to nickel ion
YSA_RS17385	COG1695	Transcriptional regulator
YSA_RS17395	COG1113	amino acid transport
YSA_RS17400	COG0069	glutamate synthase activity
YSA_RS17405	COG1201	RNA secondary structure unwinding
YSA_RS17410	COG0494	nUDIX hydrolase
YSA_RS17415	COG0583	DNA-binding transcription factor activity
YSA_RS17420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YSA_RS17440	COG1126	abc transporter atp-binding protein
YSA_RS17445	COG0765	amino acid transport
YSA_RS17450	COG0765	amino acid transport
YSA_RS17455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS17475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YSA_RS17485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YSA_RS17490	COG3842	ATPase activity
YSA_RS17495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YSA_RS17500	COG0243	molybdopterin cofactor binding
YSA_RS17505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YSA_RS17520	COG0450	alkyl hydroperoxide reductase
YSA_RS17525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YSA_RS17530	COG0418	dihydroorotase activity
YSA_RS17540	COG0137	argininosuccinate synthase activity
YSA_RS17550	COG2197	response regulator
YSA_RS17560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YSA_RS17570	COG4659	FMN binding
YSA_RS17580	COG4657	Part of a membrane complex involved in electron transport
YSA_RS17585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YSA_RS17585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YSA_RS17590	COG0489	protein tyrosine kinase activity
YSA_RS17595	COG1278	Cold shock
YSA_RS17600	COG0717	Belongs to the dCTP deaminase family
YSA_RS17615	COG1201	RNA secondary structure unwinding
YSA_RS17625	COG1793	dna ligase
YSA_RS17630	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YSA_RS17630	COG1793	dna ligase
YSA_RS17635	COG2366	antibiotic biosynthetic process
YSA_RS17640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS17645	COG1045	serine acetyltransferase
YSA_RS17650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YSA_RS17655	COG2814	Major facilitator Superfamily
YSA_RS17665	COG0653	protein targeting
YSA_RS17675	COG3012	SEC-C Motif Domain Protein
YSA_RS17705	COG1199	ATP-dependent helicase activity
YSA_RS17725	COG0259	pyridoxamine-phosphate oxidase activity
YSA_RS17740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YSA_RS17745	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
YSA_RS17785	COG2084	Dehydrogenase
YSA_RS17795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YSA_RS17815	COG1289	transmembrane transporter activity
YSA_RS17835	COG5001	Diguanylate cyclase
YSA_RS17835	COG3300	MHYT domain
YSA_RS17840	COG3706	GGDEF domain
YSA_RS17845	COG2116	formate transmembrane transporter activity
YSA_RS17880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YSA_RS17890	COG0252	asparaginase activity
YSA_RS17895	COG3318	Belongs to the UPF0149 family
YSA_RS17895	COG3012	SEC-C Motif Domain Protein
YSA_RS17900	COG0625	glutathione transferase activity
YSA_RS17910	COG0583	DNA-binding transcription factor activity
YSA_RS17935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YSA_RS17945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YSA_RS17955	COG3077	Addiction module antitoxin, RelB DinJ family
YSA_RS17965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YSA_RS17970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YSA_RS17970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YSA_RS17975	COG0745	RESPONSE REGULATOR receiver
YSA_RS17980	COG2205	protein histidine kinase activity
YSA_RS18010	COG1301	dicarboxylic acid transport
YSA_RS18020	COG4807	Protein conserved in bacteria
YSA_RS18030	COG0519	Catalyzes the synthesis of GMP from XMP
YSA_RS18055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YSA_RS18060	COG3158	transport of potassium into the cell
YSA_RS18090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YSA_RS18100	COG0442	prolyl-tRNA aminoacylation
YSA_RS18115	COG2900	Belongs to the SlyX family
YSA_RS18125	COG0783	Belongs to the Dps family
YSA_RS18140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YSA_RS18145	COG0217	transcriptional regulatory protein
YSA_RS18150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YSA_RS18155	COG0632	four-way junction helicase activity
YSA_RS18160	COG2255	four-way junction helicase activity
YSA_RS18165	COG0824	Thioesterase
YSA_RS18185	COG0823	Involved in the tonB-independent uptake of proteins
YSA_RS18190	COG2885	chlorophyll binding
YSA_RS18195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YSA_RS18200	COG0602	queuosine metabolic process
YSA_RS18205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YSA_RS18220	COG0840	transmembrane signaling receptor activity
YSA_RS18225	COG0531	amino acid
YSA_RS18230	COG5339	Protein conserved in bacteria
YSA_RS18235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YSA_RS18245	COG0425	Belongs to the sulfur carrier protein TusA family
YSA_RS18255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YSA_RS18265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YSA_RS18270	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YSA_RS18275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YSA_RS18280	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YSA_RS18405	COG0616	signal peptide processing
YSA_RS18510	COG3179	chitinase
YSA_RS18600	COG0579	oxidoreductase
YSA_RS18605	COG0640	Transcriptional regulator
YSA_RS18610	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS18625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YSA_RS18630	COG3938	Belongs to the proline racemase family
YSA_RS18635	COG0531	amino acid
YSA_RS18645	COG0583	DNA-binding transcription factor activity
YSA_RS18650	COG0521	Mo-molybdopterin cofactor biosynthetic process
YSA_RS18655	COG3781	membrane
YSA_RS18660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YSA_RS18670	COG1522	sequence-specific DNA binding
YSA_RS18675	COG0626	cystathionine gamma-synthase activity
YSA_RS18695	COG3100	YcgL domain-containing protein
YSA_RS18710	COG2983	Belongs to the UPF0260 family
YSA_RS18745	COG0121	glutamine amidotransferase
YSA_RS18760	COG2814	Major facilitator Superfamily
YSA_RS18765	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YSA_RS18770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YSA_RS18775	COG1984	allophanate hydrolase subunit 2
YSA_RS18795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YSA_RS18820	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YSA_RS18845	COG1295	ribonuclease BN
YSA_RS18850	COG0242	peptide deformylase activity
YSA_RS18870	COG3795	YCII-related domain
YSA_RS18880	COG4941	Belongs to the sigma-70 factor family
YSA_RS18885	COG2030	dehydratase
YSA_RS18890	COG2267	carboxylic ester hydrolase activity
YSA_RS18895	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS18900	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS18905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS18910	COG0174	glutamine synthetase
YSA_RS18915	COG1643	Atp-dependent helicase
YSA_RS18925	COG2188	Transcriptional regulator
YSA_RS18935	COG1132	(ABC) transporter
YSA_RS18945	COG2267	carboxylic ester hydrolase activity
YSA_RS18960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YSA_RS18990	COG0668	transmembrane transport
YSA_RS18995	COG0513	Belongs to the DEAD box helicase family
YSA_RS19030	COG0583	DNA-binding transcription factor activity
YSA_RS19050	COG0840	transmembrane signaling receptor activity
YSA_RS19065	COG2832	Protein of unknown function (DUF454)
YSA_RS19075	COG0514	ATP-dependent DNA helicase (RecQ)
YSA_RS19085	COG1752	Esterase of the alpha-beta hydrolase superfamily
YSA_RS19100	COG2207	Transcriptional regulator
YSA_RS19120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YSA_RS19125	COG0778	Nitroreductase
YSA_RS19140	COG0745	RESPONSE REGULATOR receiver
YSA_RS19145	COG2350	Protein conserved in bacteria
YSA_RS19150	COG2917	probably involved in intracellular septation
YSA_RS19155	COG0613	PHP domain protein
YSA_RS19160	COG0009	L-threonylcarbamoyladenylate synthase
YSA_RS19170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
YSA_RS19180	COG1113	amino acid transport
YSA_RS19190	COG0247	lactate metabolic process
YSA_RS19190	COG0277	FAD linked oxidase domain protein
YSA_RS19205	COG2154	pterin-4-alpha-carbinolamine dehydratase
YSA_RS19225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YSA_RS19230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS19235	COG4215	(ABC) transporter
YSA_RS19255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YSA_RS19270	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS19275	COG3724	N-succinylarginine dihydrolase activity
YSA_RS19285	COG2988	succinylglutamate desuccinylase activity
YSA_RS19290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YSA_RS19295	COG0527	aspartate kinase activity
YSA_RS19300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YSA_RS19330	COG2239	Acts as a magnesium transporter
YSA_RS19350	COG1113	amino acid transport
YSA_RS19360	COG3706	GGDEF domain
YSA_RS19365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YSA_RS19375	COG0022	dehydrogenase e1 component
YSA_RS19380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YSA_RS19385	COG1522	sequence-specific DNA binding
YSA_RS19395	COG0477	Major facilitator Superfamily
YSA_RS19400	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
YSA_RS19420	COG0835	chemotaxis
YSA_RS19420	COG0784	Response regulator, receiver
YSA_RS19425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YSA_RS19430	COG1815	bacterial-type flagellum-dependent cell motility
YSA_RS19450	COG4787	bacterial-type flagellum-dependent cell motility
YSA_RS19460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YSA_RS19465	COG1706	bacterial-type flagellum-dependent cell motility
YSA_RS19510	COG0438	transferase activity, transferring glycosyl groups
YSA_RS19510	COG1216	Glycosyl transferase, family 2
YSA_RS19515	COG2089	acid synthase
YSA_RS19520	COG0028	Belongs to the TPP enzyme family
YSA_RS19525	COG0275	rRNA processing
YSA_RS19530	COG1088	dTDP-glucose 4,6-dehydratase activity
YSA_RS19540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YSA_RS19585	COG1677	Flagellar hook-basal body complex protein FliE
YSA_RS19610	COG2882	bacterial-type flagellum organization
YSA_RS19620	COG0745	RESPONSE REGULATOR receiver
YSA_RS19660	COG1987	bacterial-type flagellum assembly
YSA_RS19695	COG1181	Belongs to the D-alanine--D-alanine ligase family
YSA_RS19700	COG1802	Transcriptional regulator
YSA_RS19705	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YSA_RS19730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YSA_RS19735	COG0643	Histidine kinase
YSA_RS19735	COG0784	Response regulator, receiver
YSA_RS19735	COG2198	Histidine kinase
YSA_RS19740	COG2201	protein-glutamate methylesterase activity
YSA_RS19745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YSA_RS19750	COG1360	Flagellar Motor Protein
YSA_RS19755	COG1192	Involved in chromosome partitioning
YSA_RS19765	COG0835	chemotaxis
YSA_RS19780	COG2257	FlhB HrpN YscU SpaS Family
YSA_RS19790	COG4133	protoheme IX ABC transporter activity
YSA_RS19810	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
YSA_RS19815	COG1138	Cytochrome C-type biogenesis protein
YSA_RS19840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YSA_RS19875	COG1953	Uracil, thiamine, allantoin
YSA_RS19880	COG1522	sequence-specific DNA binding
YSA_RS19890	COG0116	Belongs to the methyltransferase superfamily
YSA_RS19890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YSA_RS19900	COG0668	transmembrane transport
YSA_RS19910	COG0477	Major facilitator Superfamily
YSA_RS19925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YSA_RS19935	COG0469	pyruvate kinase activity
YSA_RS19945	COG2084	Dehydrogenase
YSA_RS19950	COG3622	Belongs to the hyi family
YSA_RS19955	COG3960	tartronate-semialdehyde synthase activity
YSA_RS19970	COG2354	Protein conserved in bacteria
YSA_RS19985	COG2233	PERMEase
YSA_RS19995	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
YSA_RS20015	COG2252	PERMEase
YSA_RS20025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YSA_RS20030	COG0402	S-adenosylhomocysteine deaminase activity
YSA_RS20040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YSA_RS20060	COG3115	cell septum assembly
YSA_RS20065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YSA_RS20070	COG0789	Transcriptional regulator
YSA_RS20090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YSA_RS20095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YSA_RS20100	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YSA_RS20105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YSA_RS20110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YSA_RS20130	COG2217	Heavy metal translocating P-type atpase
YSA_RS20140	COG0348	domain, Protein
YSA_RS20145	COG2010	Cytochrome c
YSA_RS20160	COG3278	Belongs to the heme-copper respiratory oxidase family
YSA_RS20165	COG2010	Cytochrome c
YSA_RS20180	COG3278	Belongs to the heme-copper respiratory oxidase family
YSA_RS20190	COG3123	guanosine phosphorylase activity
YSA_RS20235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YSA_RS20260	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
YSA_RS20260	COG3608	succinylglutamate desuccinylase aspartoacylase
YSA_RS20265	COG2068	MobA-Related Protein
YSA_RS20310	COG0642	Histidine kinase
YSA_RS20350	COG0477	Major facilitator Superfamily
YSA_RS20360	COG2944	sequence-specific DNA binding
YSA_RS20390	COG2885	chlorophyll binding
YSA_RS20395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS20420	COG2009	succinate dehydrogenase
YSA_RS20425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YSA_RS20430	COG1053	succinate dehydrogenase
YSA_RS20450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YSA_RS20455	COG0045	succinate-CoA ligase (ADP-forming) activity
YSA_RS20515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YSA_RS20535	COG1136	(ABC) transporter
YSA_RS20535	COG0577	efflux transmembrane transporter activity
YSA_RS20540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS20560	COG0326	Molecular chaperone. Has ATPase activity
YSA_RS20570	COG1741	Belongs to the pirin family
YSA_RS20585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YSA_RS20590	COG3437	response regulator, receiver
YSA_RS20590	COG2205	protein histidine kinase activity
YSA_RS20590	COG3850	Histidine kinase
YSA_RS20590	COG4999	Histidine kinase
YSA_RS20605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YSA_RS20640	COG0628	permease
YSA_RS20650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YSA_RS20660	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YSA_RS20665	COG2205	protein histidine kinase activity
YSA_RS20670	COG0745	RESPONSE REGULATOR receiver
YSA_RS20675	COG0583	DNA-binding transcription factor activity
YSA_RS20680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YSA_RS20690	COG4172	Belongs to the ABC transporter superfamily
YSA_RS20695	COG4239	(ABC) transporter, permease
YSA_RS20700	COG4174	ABC transporter (Permease)
YSA_RS20705	COG4166	transmembrane transport
YSA_RS20710	COG4166	transmembrane transport
YSA_RS20715	COG1388	LysM domain
YSA_RS20715	COG0741	lytic transglycosylase activity
YSA_RS20720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YSA_RS20730	COG0328	RNA-DNA hybrid ribonuclease activity
YSA_RS20750	COG0431	NADPH-dependent FMN reductase
YSA_RS20785	COG1007	ATP synthesis coupled electron transport
YSA_RS20800	COG0713	ATP synthesis coupled electron transport
YSA_RS20810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YSA_RS20815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YSA_RS20820	COG1034	ATP synthesis coupled electron transport
YSA_RS20835	COG0649	NAD binding
YSA_RS20835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YSA_RS20840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YSA_RS20845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YSA_RS20875	COG0659	secondary active sulfate transmembrane transporter activity
YSA_RS20880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YSA_RS20895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YSA_RS20900	COG0583	DNA-binding transcription factor activity
YSA_RS20905	COG1113	amino acid transport
YSA_RS20910	COG2050	protein possibly involved in aromatic compounds catabolism
YSA_RS20910	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YSA_RS20915	COG0625	glutathione transferase activity
YSA_RS20920	COG0306	phosphate transporter
YSA_RS20930	COG0456	acetyltransferase
YSA_RS20930	COG1846	Transcriptional regulator
YSA_RS20945	COG0322	excinuclease ABC activity
YSA_RS20985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YSA_RS21000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YSA_RS21005	COG1960	acyl-CoA dehydrogenase activity
YSA_RS21010	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS21020	COG0366	Alpha amylase catalytic
YSA_RS21025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YSA_RS21035	COG3568	Endonuclease Exonuclease Phosphatase
YSA_RS21055	COG1640	4-alpha-glucanotransferase
YSA_RS21060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YSA_RS21065	COG0297	glycogen (starch) synthase activity
YSA_RS21070	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
YSA_RS21075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YSA_RS21080	COG3387	PFAM Glycoside hydrolase 15-related
YSA_RS21090	COG1309	transcriptional regulator
YSA_RS21100	COG0493	'glutamate synthase
YSA_RS21110	COG1953	Uracil, thiamine, allantoin
YSA_RS21120	COG1234	tRNA 3'-trailer cleavage
YSA_RS21125	COG3040	lipid binding
YSA_RS21130	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YSA_RS21135	COG1024	Enoyl-CoA hydratase
YSA_RS21140	COG2816	NAD+ diphosphatase activity
YSA_RS21160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS21165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YSA_RS21170	COG2153	protein acetylation
YSA_RS21175	COG2850	peptidyl-arginine hydroxylation
YSA_RS21185	COG2915	High frequency lysogenization protein hflD homolog
YSA_RS21190	COG0482	sulfurtransferase activity
YSA_RS21210	COG1278	Cold shock
YSA_RS21215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YSA_RS21220	COG0542	response to heat
YSA_RS21225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YSA_RS21230	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
YSA_RS21235	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YSA_RS21240	COG1674	ftsk spoiiie
YSA_RS21245	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YSA_RS21250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YSA_RS21255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YSA_RS21260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YSA_RS21265	COG1648	precorrin-2 dehydrogenase activity
YSA_RS21265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YSA_RS21270	COG0435	Glutathione S-transferase
YSA_RS21275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YSA_RS21280	COG2920	part of a sulfur-relay system
YSA_RS21300	COG2233	PERMEase
YSA_RS21315	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS21325	COG1850	ribulose-bisphosphate carboxylase activity
YSA_RS21335	COG0477	Major facilitator Superfamily
YSA_RS21340	COG0469	pyruvate kinase activity
YSA_RS21345	COG0148	phosphopyruvate hydratase activity
YSA_RS21350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YSA_RS21360	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS21380	COG0523	cobalamin synthesis protein
YSA_RS21405	COG0667	Aldo Keto reductase
YSA_RS21495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YSA_RS21500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YSA_RS21505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
YSA_RS21525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YSA_RS21535	COG4948	Mandelate Racemase Muconate Lactonizing
YSA_RS21540	COG0747	negative chemotaxis
YSA_RS21545	COG0601	transmembrane transport
YSA_RS21550	COG0747	negative chemotaxis
YSA_RS21555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YSA_RS21560	COG0444	Belongs to the ABC transporter superfamily
YSA_RS21565	COG4608	Belongs to the ABC transporter superfamily
YSA_RS21580	COG1725	Transcriptional regulator
YSA_RS21590	COG1309	transcriptional regulator
YSA_RS21595	COG2010	Cytochrome c
YSA_RS21595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YSA_RS21600	COG2080	2 iron, 2 sulfur cluster binding
YSA_RS21605	COG1846	Transcriptional regulator
YSA_RS21610	COG2309	aminopeptidase activity
YSA_RS21615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YSA_RS21620	COG0596	Alpha beta hydrolase
YSA_RS21625	COG3473	Maleate cis-trans isomerase
YSA_RS21630	COG1335	isochorismatase
YSA_RS21635	COG2271	Major facilitator Superfamily
YSA_RS21660	COG2199	diguanylate cyclase activity
YSA_RS21665	COG0490	domain, Protein
YSA_RS21665	COG0471	metal ion transport
YSA_RS21690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YSA_RS21695	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS21715	COG0616	signal peptide processing
YSA_RS21795	COG5532	Uncharacterized conserved protein (DUF2303)
YSA_RS21835	COG2433	Pfam Transposase IS66
YSA_RS21875	COG0305	Participates in initiation and elongation during chromosome replication
YSA_RS21955	COG4695	Portal protein
YSA_RS21960	COG0740	serine-type endopeptidase activity
YSA_RS22070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YSA_RS22195	COG1090	epimerase
YSA_RS22215	COG1064	alcohol dehydrogenase
YSA_RS22225	COG2259	Doxx family
YSA_RS22235	COG4191	Histidine kinase
YSA_RS22235	COG0784	Response regulator, receiver
YSA_RS22240	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
YSA_RS22245	COG0745	RESPONSE REGULATOR receiver
YSA_RS22250	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YSA_RS22260	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
YSA_RS22290	COG2863	cytochrome
YSA_RS22295	COG3258	Cytochrome c
YSA_RS22315	COG3842	ATPase activity
YSA_RS22320	COG1177	transmembrane transport
YSA_RS22325	COG1176	ABC-type spermidine putrescine transport system, permease component I
YSA_RS22335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YSA_RS22350	COG0583	DNA-binding transcription factor activity
YSA_RS22390	COG1121	(ABC) transporter
YSA_RS22430	COG1686	Belongs to the peptidase S11 family
YSA_RS22455	COG2020	methyltransferase activity
YSA_RS22465	COG1309	transcriptional regulator
YSA_RS22500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YSA_RS22535	COG0784	Response regulator, receiver
YSA_RS22535	COG2198	Histidine kinase
YSA_RS22535	COG2205	protein histidine kinase activity
YSA_RS22540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YSA_RS22555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS22555	COG2205	protein histidine kinase activity
YSA_RS22555	COG0784	Response regulator, receiver
YSA_RS22555	COG2198	Histidine kinase
YSA_RS22565	COG1250	3-hydroxyacyl-CoA dehydrogenase
YSA_RS22570	COG0183	Belongs to the thiolase family
YSA_RS22580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YSA_RS22585	COG2807	transmembrane transport
YSA_RS22600	COG3193	protein, possibly involved in utilization of glycolate and propanediol
YSA_RS22605	COG0247	lactate metabolic process
YSA_RS22610	COG0277	FAD linked oxidase domain protein
YSA_RS22615	COG0277	FAD linked oxidase domain protein
YSA_RS22620	COG2186	Transcriptional regulator
YSA_RS22635	COG0768	penicillin binding
YSA_RS22670	COG0577	efflux transmembrane transporter activity
YSA_RS22680	COG1024	Enoyl-CoA hydratase
YSA_RS22705	COG0833	amino acid
YSA_RS22710	COG1024	Enoyl-CoA hydratase
YSA_RS22715	COG1960	acyl-CoA dehydrogenase activity
YSA_RS22730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YSA_RS22745	COG2249	NAD(P)H dehydrogenase (quinone) activity
YSA_RS22765	COG3192	ethanolamine utilization protein
YSA_RS22790	COG4948	Mandelate Racemase Muconate Lactonizing
YSA_RS22795	COG4829	muconolactone delta-isomerase
YSA_RS22800	COG3485	protocatechuate 3,4-dioxygenase
YSA_RS22810	COG5001	Diguanylate cyclase
YSA_RS22815	COG0656	L-ascorbic acid biosynthetic process
YSA_RS22830	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
YSA_RS22840	COG0477	Major facilitator Superfamily
YSA_RS22850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YSA_RS22855	COG5001	Diguanylate cyclase
YSA_RS22855	COG3300	MHYT domain
YSA_RS22860	COG1611	Belongs to the LOG family
YSA_RS22865	COG2855	membrane
YSA_RS22875	COG2030	dehydratase
YSA_RS22885	COG2814	Major facilitator Superfamily
YSA_RS22900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
YSA_RS22915	COG1280	lysine exporter protein (LysE YggA)
YSA_RS22920	COG4191	Histidine kinase
YSA_RS22920	COG0784	Response regulator, receiver
YSA_RS22925	COG2816	NAD+ diphosphatase activity
YSA_RS22930	COG2186	Transcriptional regulator
YSA_RS22935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YSA_RS22945	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS22950	COG2267	carboxylic ester hydrolase activity
YSA_RS22960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YSA_RS22970	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
YSA_RS22985	COG1959	2 iron, 2 sulfur cluster binding
YSA_RS22990	COG2207	Transcriptional regulator
YSA_RS23010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YSA_RS23015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YSA_RS23025	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YSA_RS23035	COG4991	sh3 domain protein
YSA_RS23050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YSA_RS23090	COG1944	ATP diphosphatase activity
YSA_RS23130	COG4335	DNA alkylation repair
YSA_RS23155	COG2186	Transcriptional regulator
YSA_RS23160	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS23165	COG2721	sulfolactate sulfo-lyase activity
YSA_RS23170	COG2271	Major facilitator Superfamily
YSA_RS23175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YSA_RS23180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
YSA_RS23190	COG2801	Transposase and inactivated derivatives
YSA_RS23200	COG1131	(ABC) transporter
YSA_RS23275	COG5002	protein histidine kinase activity
YSA_RS23275	COG2205	protein histidine kinase activity
YSA_RS23275	COG0784	Response regulator, receiver
YSA_RS23310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS23315	COG0583	DNA-binding transcription factor activity
YSA_RS23320	COG3048	D-serine ammonia-lyase activity
YSA_RS23325	COG2610	gluconate transmembrane transporter activity
YSA_RS23335	COG1305	Transglutaminase-like
YSA_RS23345	COG2308	Evidence 4 Homologs of previously reported genes of
YSA_RS23365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YSA_RS23375	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS23385	COG0583	DNA-binding transcription factor activity
YSA_RS23390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YSA_RS23405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YSA_RS23405	COG0678	peroxiredoxin activity
YSA_RS23410	COG0583	DNA-binding transcription factor activity
YSA_RS23425	COG1473	amidohydrolase
YSA_RS23440	COG0708	Exodeoxyribonuclease III
YSA_RS23480	COG0431	NADPH-dependent FMN reductase
YSA_RS23485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YSA_RS23490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YSA_RS23495	COG0640	Transcriptional regulator
YSA_RS23505	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS23515	COG0693	protein deglycase activity
YSA_RS23520	COG2323	membrane
YSA_RS23550	COG3046	protein related to deoxyribodipyrimidine photolyase
YSA_RS23560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YSA_RS23575	COG4221	oxidoreductase activity
YSA_RS23585	COG1366	Belongs to the anti-sigma-factor antagonist family
YSA_RS23590	COG0789	Transcriptional regulator
YSA_RS23595	COG0668	transmembrane transport
YSA_RS23615	COG0589	response to stress
YSA_RS23685	COG1129	ABC transporter
YSA_RS23690	COG1172	Belongs to the binding-protein-dependent transport system permease family
YSA_RS23695	COG1172	Belongs to the binding-protein-dependent transport system permease family
YSA_RS23700	COG1960	acyl-CoA dehydrogenase activity
YSA_RS23705	COG0431	NADPH-dependent FMN reductase
YSA_RS23730	COG1172	Belongs to the binding-protein-dependent transport system permease family
YSA_RS23740	COG3829	transcription factor binding
YSA_RS23750	COG4175	Glycine betaine
YSA_RS23755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YSA_RS23760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YSA_RS23770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YSA_RS23815	COG2249	NAD(P)H dehydrogenase (quinone) activity
YSA_RS23830	COG0604	alcohol dehydrogenase
YSA_RS23830	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS23830	COG3321	synthase
YSA_RS23850	COG4948	Mandelate Racemase Muconate Lactonizing
YSA_RS23860	COG0583	DNA-binding transcription factor activity
YSA_RS23865	COG2721	sulfolactate sulfo-lyase activity
YSA_RS23880	COG2271	Major facilitator Superfamily
YSA_RS23890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YSA_RS23890	COG1199	ATP-dependent helicase activity
YSA_RS23900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YSA_RS23905	COG0829	nickel cation binding
YSA_RS23910	COG0831	urea catabolic process
YSA_RS23915	COG0832	Belongs to the urease beta subunit family
YSA_RS23920	COG0804	urea catabolic process
YSA_RS23925	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
YSA_RS23935	COG0830	nickel cation binding
YSA_RS23940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YSA_RS24000	COG0840	transmembrane signaling receptor activity
YSA_RS24005	COG1968	undecaprenyl-diphosphatase activity
YSA_RS24025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YSA_RS24030	COG1252	NADH dehydrogenase
YSA_RS24040	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS24040	COG0446	pyridine nucleotide-disulphide oxidoreductase
YSA_RS24050	COG0235	Class ii aldolase
YSA_RS24060	COG0393	Putative heavy-metal-binding
YSA_RS24100	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS24115	COG1396	sequence-specific DNA binding
YSA_RS24115	COG1917	Cupin 2, conserved barrel domain protein
YSA_RS24120	COG0477	Major facilitator Superfamily
YSA_RS24125	COG3038	cytochrome b561
YSA_RS24135	COG1595	DNA-templated transcription, initiation
YSA_RS24145	COG0708	Exodeoxyribonuclease III
YSA_RS24155	COG0729	surface antigen
YSA_RS24195	COG2366	antibiotic biosynthetic process
YSA_RS24200	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YSA_RS24210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YSA_RS24215	COG0215	cysteine-tRNA ligase activity
YSA_RS24220	COG2205	protein histidine kinase activity
YSA_RS24225	COG0745	RESPONSE REGULATOR receiver
YSA_RS24230	COG1802	Transcriptional regulator
YSA_RS24240	COG0579	oxidoreductase
YSA_RS24245	COG1113	amino acid transport
YSA_RS24255	COG0113	porphobilinogen synthase activity
YSA_RS24270	COG0307	riboflavin synthase, alpha
YSA_RS24285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YSA_RS24295	COG1984	allophanate hydrolase subunit 2
YSA_RS24310	COG0579	oxidoreductase
YSA_RS24320	COG4106	trans-aconitate 2-methyltransferase activity
YSA_RS24330	COG0019	diaminopimelate decarboxylase activity
YSA_RS24355	COG0625	glutathione transferase activity
YSA_RS24370	COG0488	(ABC) transporter
YSA_RS24390	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YSA_RS24415	COG2135	peptidase activity
YSA_RS24425	COG1858	cytochrome C peroxidase
YSA_RS24435	COG4191	Histidine kinase
YSA_RS24435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS24450	COG1477	protein flavinylation
YSA_RS24455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YSA_RS24475	COG0642	Histidine kinase
YSA_RS24480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YSA_RS24485	COG0697	spore germination
YSA_RS24545	COG0583	DNA-binding transcription factor activity
YSA_RS24570	COG0189	ligase activity
YSA_RS24605	COG0456	acetyltransferase
YSA_RS24605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
YSA_RS24630	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS24630	COG0446	pyridine nucleotide-disulphide oxidoreductase
YSA_RS24665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YSA_RS24670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YSA_RS24675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YSA_RS24680	COG0477	Major facilitator Superfamily
YSA_RS24740	COG2175	clavaminate synthase activity
YSA_RS24745	COG3246	L-lysine catabolic process to acetate
YSA_RS24750	COG2814	Major facilitator Superfamily
YSA_RS24795	COG1960	acyl-CoA dehydrogenase activity
YSA_RS24800	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS24810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YSA_RS24825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YSA_RS24910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YSA_RS25070	COG3179	chitinase
YSA_RS25095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YSA_RS25100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YSA_RS25105	COG4574	serine-type endopeptidase inhibitor activity
YSA_RS25110	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS25115	COG2610	gluconate transmembrane transporter activity
YSA_RS25120	COG3829	transcription factor binding
YSA_RS25120	COG3290	protein histidine kinase activity
YSA_RS25125	COG4239	(ABC) transporter, permease
YSA_RS25130	COG4174	ABC transporter (Permease)
YSA_RS25135	COG4166	transmembrane transport
YSA_RS25140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YSA_RS25145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YSA_RS25150	COG1881	PFAM PEBP family protein
YSA_RS25300	COG3209	COG3209 Rhs family protein
YSA_RS25345	COG1473	amidohydrolase
YSA_RS25355	COG0154	amidase activity
YSA_RS25360	COG1414	Transcriptional regulator
YSA_RS25370	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS25375	COG1053	succinate dehydrogenase
YSA_RS25390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YSA_RS25395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YSA_RS25410	COG0587	DNA-directed DNA polymerase activity
YSA_RS25415	COG0656	L-ascorbic acid biosynthetic process
YSA_RS25425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
YSA_RS25435	COG2031	fatty acid transporter
YSA_RS25440	COG1396	sequence-specific DNA binding
YSA_RS25465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YSA_RS25505	COG1215	transferase activity, transferring glycosyl groups
YSA_RS25510	COG2990	Protein conserved in bacteria
YSA_RS25520	COG1215	transferase activity, transferring glycosyl groups
YSA_RS25535	COG0583	DNA-binding transcription factor activity
YSA_RS25540	COG1760	l-serine dehydratase
YSA_RS25550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YSA_RS25560	COG0174	glutamine synthetase
YSA_RS25575	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS25580	COG0583	DNA-binding transcription factor activity
YSA_RS25640	COG2814	Major facilitator Superfamily
YSA_RS25645	COG3485	protocatechuate 3,4-dioxygenase
YSA_RS25650	COG3135	benzoate transporter
YSA_RS25670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YSA_RS25675	COG1902	pentaerythritol trinitrate reductase activity
YSA_RS25680	COG0667	Aldo Keto reductase
YSA_RS25685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YSA_RS25690	COG2271	Major facilitator Superfamily
YSA_RS25695	COG3835	regulator
YSA_RS25700	COG1929	Belongs to the glycerate kinase type-1 family
YSA_RS25705	COG0583	DNA-binding transcription factor activity
YSA_RS25725	COG1999	signal sequence binding
YSA_RS25740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
YSA_RS25745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
YSA_RS25755	COG0402	S-adenosylhomocysteine deaminase activity
YSA_RS25760	COG2423	ornithine cyclodeaminase activity
YSA_RS25765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YSA_RS25795	COG4251	negative regulation of phosphorylation
YSA_RS25795	COG3706	GGDEF domain
YSA_RS25795	COG2203	Gaf domain
YSA_RS25795	COG5001	Diguanylate cyclase
YSA_RS25805	COG1285	pathogenesis
YSA_RS25815	COG0385	Bile acid
YSA_RS25820	COG2837	iron assimilation
YSA_RS25825	COG0667	Aldo Keto reductase
YSA_RS25850	COG2890	protein-(glutamine-N5) methyltransferase activity
YSA_RS25855	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YSA_RS25880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YSA_RS25910	COG0392	lysyltransferase activity
YSA_RS25915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YSA_RS25920	COG3568	Endonuclease Exonuclease Phosphatase
YSA_RS25950	COG2030	dehydratase
YSA_RS25950	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS25965	COG3162	membrane
YSA_RS25970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YSA_RS25975	COG2151	metal-sulfur cluster biosynthetic enzyme
YSA_RS25980	COG3396	Phenylacetate-CoA oxygenase
YSA_RS25985	COG3460	Phenylacetate-CoA oxygenase
YSA_RS25990	COG3396	Phenylacetate-CoA oxygenase
YSA_RS26000	COG0183	Belongs to the thiolase family
YSA_RS26005	COG2050	protein possibly involved in aromatic compounds catabolism
YSA_RS26010	COG1250	3-hydroxyacyl-CoA dehydrogenase
YSA_RS26015	COG1024	Enoyl-CoA hydratase
YSA_RS26020	COG1024	Enoyl-CoA hydratase
YSA_RS26030	COG3327	negative regulation of DNA-templated transcription, initiation
YSA_RS26040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YSA_RS26065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YSA_RS26105	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
YSA_RS26115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YSA_RS26135	COG0589	response to stress
YSA_RS26205	COG4974	Belongs to the 'phage' integrase family
YSA_RS26215	COG1473	amidohydrolase
YSA_RS26225	COG0583	DNA-binding transcription factor activity
YSA_RS26240	COG3384	dioxygenase
YSA_RS26250	COG2267	carboxylic ester hydrolase activity
YSA_RS26255	COG0778	Nitroreductase
YSA_RS26265	COG1942	4-Oxalocrotonate Tautomerase
YSA_RS26280	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS26285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YSA_RS26290	COG1082	Xylose isomerase domain protein TIM barrel
YSA_RS26305	COG0583	DNA-binding transcription factor activity
YSA_RS26325	COG4948	Mandelate Racemase Muconate Lactonizing
YSA_RS26330	COG4829	muconolactone delta-isomerase
YSA_RS26375	COG0427	acetyl-CoA hydrolase
YSA_RS26385	COG2814	Major facilitator Superfamily
YSA_RS26390	COG1946	Acyl-CoA thioesterase
YSA_RS26395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
YSA_RS26405	COG0583	DNA-binding transcription factor activity
YSA_RS26430	COG2301	Belongs to the HpcH HpaI aldolase family
YSA_RS26435	COG1960	acyl-CoA dehydrogenase activity
YSA_RS26440	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
YSA_RS26450	COG2814	Major facilitator Superfamily
YSA_RS26460	COG1473	amidohydrolase
YSA_RS26505	COG0531	amino acid
YSA_RS26525	COG0861	Integral membrane protein TerC family
YSA_RS26540	COG0028	Belongs to the TPP enzyme family
YSA_RS26545	COG2080	2 iron, 2 sulfur cluster binding
YSA_RS26550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YSA_RS26555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YSA_RS26560	COG1058	Belongs to the CinA family
YSA_RS26560	COG1546	Belongs to the CinA family
YSA_RS26575	COG1063	alcohol dehydrogenase
YSA_RS26585	COG1028	Short-chain dehydrogenase reductase Sdr
YSA_RS26590	COG1538	Outer membrane efflux protein
YSA_RS26605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YSA_RS26610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YSA_RS26615	COG2814	Major facilitator Superfamily
YSA_RS26620	COG1469	GTP cyclohydrolase I activity
YSA_RS26640	COG1301	dicarboxylic acid transport
YSA_RS26650	COG0583	DNA-binding transcription factor activity
YSA_RS26675	COG3706	GGDEF domain
YSA_RS26680	COG0668	transmembrane transport
YSA_RS26685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YSA_RS26695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YSA_RS26720	COG2814	Major facilitator Superfamily
YSA_RS26730	COG0667	Aldo Keto reductase
YSA_RS26735	COG2205	protein histidine kinase activity
YSA_RS26740	COG0745	RESPONSE REGULATOR receiver
YSA_RS26755	COG2356	endonuclease I
YSA_RS26765	COG2271	Major facilitator Superfamily
YSA_RS26770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YSA_RS26780	COG1609	Transcriptional regulator
YSA_RS26840	COG2271	Major facilitator Superfamily
YSA_RS26855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YSA_RS26945	COG3813	Protein conserved in bacteria
YSA_RS26950	COG2197	response regulator
YSA_RS26955	COG2205	protein histidine kinase activity
YSA_RS26955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YSA_RS26965	COG1609	Transcriptional regulator
YSA_RS26970	COG3265	gluconokinase activity
YSA_RS26985	COG2204	response regulator
YSA_RS26990	COG2205	protein histidine kinase activity
YSA_RS26995	COG5002	protein histidine kinase activity
YSA_RS27000	COG0739	heme binding
YSA_RS27000	COG1196	nuclear chromosome segregation
YSA_RS27000	COG0741	lytic transglycosylase activity
YSA_RS27010	COG1459	type II secretion system
YSA_RS27015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS27040	COG0784	Response regulator, receiver
YSA_RS27040	COG4191	Histidine kinase
YSA_RS27060	COG2200	EAL domain
YSA_RS27070	COG1253	flavin adenine dinucleotide binding
YSA_RS27110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YSA_RS27120	COG2205	protein histidine kinase activity
YSA_RS27125	COG0745	RESPONSE REGULATOR receiver
YSA_RS27130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YSA_RS27140	COG0746	molybdenum cofactor guanylyltransferase activity
YSA_RS27145	COG0318	PFAM AMP-dependent synthetase and ligase
YSA_RS27170	COG1012	belongs to the aldehyde dehydrogenase family
YSA_RS27190	COG1132	(ABC) transporter
YSA_RS27195	COG3284	Transcriptional regulator
YSA_RS27225	COG2165	general secretion pathway protein
YSA_RS27230	COG2165	general secretion pathway protein
YSA_RS27235	COG4796	Type ii and iii secretion system protein
YSA_RS27260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YSA_RS27265	COG2204	response regulator
YSA_RS27305	COG1960	acyl-CoA dehydrogenase activity
YSA_RS27320	COG2384	SAM-dependent methyltransferase
YSA_RS27330	COG0826	peptidase U32
YSA_RS27335	COG2204	response regulator
YSA_RS27405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YSA_RS27810	COG4774	siderophore transport