locus-tag	class	description
HNQ25_RS00005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HNQ25_RS00030	COG0432	Pfam Uncharacterised protein family UPF0047
HNQ25_RS00035	COG0004	ammonium transporteR
HNQ25_RS00040	COG0347	Belongs to the P(II) protein family
HNQ25_RS00050	COG0606	chelatase, subunit chli
HNQ25_RS00055	COG0840	transmembrane signaling receptor activity
HNQ25_RS00060	COG0583	DNA-binding transcription factor activity
HNQ25_RS00075	COG0210	DNA helicase
HNQ25_RS00085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNQ25_RS00090	COG0427	acetyl-CoA hydrolase
HNQ25_RS00100	COG1917	Cupin 2, conserved barrel domain protein
HNQ25_RS00105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNQ25_RS00110	COG0251	oxidation-reduction process
HNQ25_RS00115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS00130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS00140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS00145	COG0477	Major facilitator Superfamily
HNQ25_RS00150	COG1012	belongs to the aldehyde dehydrogenase family
HNQ25_RS00245	COG0732	type I restriction modification DNA specificity domain
HNQ25_RS00255	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HNQ25_RS00265	COG4251	negative regulation of phosphorylation
HNQ25_RS00285	COG1012	belongs to the aldehyde dehydrogenase family
HNQ25_RS00305	COG0583	DNA-binding transcription factor activity
HNQ25_RS00325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HNQ25_RS00335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HNQ25_RS00360	COG0179	Fumarylacetoacetate (FAA) hydrolase
HNQ25_RS00370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HNQ25_RS00375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HNQ25_RS00380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HNQ25_RS00385	COG2721	sulfolactate sulfo-lyase activity
HNQ25_RS00400	COG5001	Diguanylate cyclase
HNQ25_RS00400	COG4251	negative regulation of phosphorylation
HNQ25_RS00400	COG2203	Gaf domain
HNQ25_RS00400	COG3706	GGDEF domain
HNQ25_RS00410	COG0625	glutathione transferase activity
HNQ25_RS00445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HNQ25_RS00465	COG3052	prosthetic group binding
HNQ25_RS00470	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HNQ25_RS00480	COG3706	GGDEF domain
HNQ25_RS00495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNQ25_RS00500	COG1256	bacterial-type flagellum assembly
HNQ25_RS00500	COG4786	Flagellar basal body rod
HNQ25_RS00505	COG0741	lytic transglycosylase activity
HNQ25_RS00510	COG1706	bacterial-type flagellum-dependent cell motility
HNQ25_RS00520	COG4786	Flagellar basal body rod
HNQ25_RS00525	COG4787	bacterial-type flagellum-dependent cell motility
HNQ25_RS00530	COG1749	Flagellar hook protein flgE
HNQ25_RS00535	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HNQ25_RS00540	COG1558	bacterial-type flagellum-dependent cell motility
HNQ25_RS00555	COG2186	Transcriptional regulator
HNQ25_RS00560	COG0277	FAD linked oxidase domain protein
HNQ25_RS00565	COG0277	FAD linked oxidase domain protein
HNQ25_RS00570	COG0247	lactate metabolic process
HNQ25_RS00575	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HNQ25_RS00580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HNQ25_RS00585	COG1620	l-lactate permease
HNQ25_RS00595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HNQ25_RS00615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNQ25_RS00620	COG1191	sigma factor activity
HNQ25_RS00645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HNQ25_RS00650	COG0739	heme binding
HNQ25_RS00665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HNQ25_RS00670	COG0581	inorganic phosphate transmembrane transporter activity
HNQ25_RS00690	COG2823	Periplasmic or secreted lipoprotein
HNQ25_RS00695	COG2204	response regulator
HNQ25_RS00700	COG5002	protein histidine kinase activity
HNQ25_RS00715	COG0784	Response regulator, receiver
HNQ25_RS00715	COG2198	Histidine kinase
HNQ25_RS00715	COG2205	protein histidine kinase activity
HNQ25_RS00725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HNQ25_RS00730	COG3850	Histidine kinase
HNQ25_RS00730	COG2205	protein histidine kinase activity
HNQ25_RS00730	COG4999	Histidine kinase
HNQ25_RS00730	COG3437	response regulator, receiver
HNQ25_RS00735	COG2198	Histidine kinase
HNQ25_RS00735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNQ25_RS00735	COG0784	Response regulator, receiver
HNQ25_RS00735	COG2205	protein histidine kinase activity
HNQ25_RS00745	COG3023	N-Acetylmuramoyl-L-alanine amidase
HNQ25_RS00750	COG2095	MarC family integral membrane protein
HNQ25_RS00755	COG2233	PERMEase
HNQ25_RS00785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HNQ25_RS00810	COG0109	protoheme IX farnesyltransferase activity
HNQ25_RS00815	COG1612	heme a metabolic process
HNQ25_RS00840	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HNQ25_RS00845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNQ25_RS00865	COG2066	Belongs to the glutaminase family
HNQ25_RS00870	COG0251	oxidation-reduction process
HNQ25_RS00880	COG0252	asparaginase activity
HNQ25_RS00885	COG1115	amino acid carrier protein
HNQ25_RS00915	COG1027	Aspartate ammonia-lyase
HNQ25_RS00920	COG0583	DNA-binding transcription factor activity
HNQ25_RS00955	COG1368	sulfuric ester hydrolase activity
HNQ25_RS01005	COG0676	glucose-6-phosphate 1-epimerase activity
HNQ25_RS01020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HNQ25_RS01025	COG1607	acyl-coa hydrolase
HNQ25_RS01045	COG0700	Nucleoside recognition
HNQ25_RS01055	COG3360	Dodecin
HNQ25_RS01065	COG3712	iron ion homeostasis
HNQ25_RS01070	COG1595	DNA-templated transcription, initiation
HNQ25_RS01080	COG0133	tryptophan synthase activity
HNQ25_RS01085	COG0159	tryptophan synthase activity
HNQ25_RS01095	COG0659	secondary active sulfate transmembrane transporter activity
HNQ25_RS01100	COG4651	solute:proton antiporter activity
HNQ25_RS01100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HNQ25_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS01110	COG0656	L-ascorbic acid biosynthetic process
HNQ25_RS01115	COG0583	DNA-binding transcription factor activity
HNQ25_RS01120	COG1686	Belongs to the peptidase S11 family
HNQ25_RS01125	COG0583	DNA-binding transcription factor activity
HNQ25_RS01130	COG3119	arylsulfatase activity
HNQ25_RS01140	COG0659	secondary active sulfate transmembrane transporter activity
HNQ25_RS01145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNQ25_RS01150	COG0408	coproporphyrinogen oxidase activity
HNQ25_RS01160	COG0009	L-threonylcarbamoyladenylate synthase
HNQ25_RS01165	COG0758	DNA mediated transformation
HNQ25_RS01170	COG1652	LysM domain
HNQ25_RS01175	COG0242	peptide deformylase activity
HNQ25_RS01180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNQ25_RS01185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNQ25_RS01190	COG0569	domain protein
HNQ25_RS01200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNQ25_RS01205	COG1012	belongs to the aldehyde dehydrogenase family
HNQ25_RS01210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HNQ25_RS01215	COG0791	NLP P60 protein
HNQ25_RS01225	COG1522	sequence-specific DNA binding
HNQ25_RS01230	COG3608	succinylglutamate desuccinylase aspartoacylase
HNQ25_RS01235	COG0006	proline dipeptidase activity
HNQ25_RS01240	COG2423	ornithine cyclodeaminase activity
HNQ25_RS01245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNQ25_RS01250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS01255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNQ25_RS01260	COG0765	amino acid transport
HNQ25_RS01265	COG0765	amino acid transport
HNQ25_RS01270	COG1126	abc transporter atp-binding protein
HNQ25_RS01300	COG2818	Glycosylase
HNQ25_RS01305	COG0752	glycyl-tRNA synthetase alpha subunit
HNQ25_RS01310	COG0751	glycine-tRNA ligase activity
HNQ25_RS01325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNQ25_RS01330	COG2267	carboxylic ester hydrolase activity
HNQ25_RS01335	COG0671	phosphoesterase, PA-phosphatase related
HNQ25_RS01335	COG2453	phosphatase
HNQ25_RS01350	COG4589	Belongs to the CDS family
HNQ25_RS01365	COG3209	COG3209 Rhs family protein
HNQ25_RS01445	COG1360	Flagellar Motor Protein
HNQ25_RS01465	COG2815	serine threonine protein kinase
HNQ25_RS01465	COG0515	serine threonine protein kinase
HNQ25_RS01500	COG2026	Addiction module toxin, RelE StbE family
HNQ25_RS01515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNQ25_RS01525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNQ25_RS01530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HNQ25_RS01535	COG0594	ribonuclease P activity
HNQ25_RS01540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HNQ25_RS01545	COG0706	membrane insertase activity
HNQ25_RS01550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNQ25_RS01555	COG0445	tRNA wobble uridine modification
HNQ25_RS01560	COG0357	Ribosomal RNA small subunit methyltransferase G
HNQ25_RS01565	COG1192	Involved in chromosome partitioning
HNQ25_RS01570	COG1475	DNA binding
HNQ25_RS01575	COG3312	ion transport
HNQ25_RS01580	COG0356	it plays a direct role in the translocation of protons across the membrane
HNQ25_RS01590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNQ25_RS01595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNQ25_RS01600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNQ25_RS01605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNQ25_RS01610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNQ25_RS01615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HNQ25_RS01620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNQ25_RS01630	COG1349	DNA-binding transcription factor activity
HNQ25_RS01635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HNQ25_RS01640	COG0024	Methionine aminopeptidase
HNQ25_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS01660	COG2207	Transcriptional regulator
HNQ25_RS01710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNQ25_RS01725	COG2814	Major facilitator Superfamily
HNQ25_RS01735	COG0477	Major facilitator Superfamily
HNQ25_RS01740	COG0583	DNA-binding transcription factor activity
HNQ25_RS01745	COG4221	oxidoreductase activity
HNQ25_RS01750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HNQ25_RS01755	COG0583	DNA-binding transcription factor activity
HNQ25_RS01760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HNQ25_RS01790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNQ25_RS01825	COG4774	siderophore transport
HNQ25_RS01830	COG1120	ATPase activity
HNQ25_RS01840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNQ25_RS01860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HNQ25_RS01870	COG2204	response regulator
HNQ25_RS01875	COG2358	TRAP transporter, solute receptor (TAXI family
HNQ25_RS01910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNQ25_RS01915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HNQ25_RS01920	COG1760	l-serine dehydratase
HNQ25_RS01925	COG0583	DNA-binding transcription factor activity
HNQ25_RS01945	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HNQ25_RS01945	COG0517	IMP dehydrogenase activity
HNQ25_RS01960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HNQ25_RS01975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HNQ25_RS01980	COG1469	GTP cyclohydrolase I activity
HNQ25_RS02010	COG0523	cobalamin synthesis protein
HNQ25_RS02030	COG1607	acyl-coa hydrolase
HNQ25_RS02045	COG0174	glutamine synthetase
HNQ25_RS02050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HNQ25_RS02065	COG2153	protein acetylation
HNQ25_RS02080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HNQ25_RS02085	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HNQ25_RS02120	COG2011	ABC-type metal ion transport system permease component
HNQ25_RS02125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNQ25_RS02135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HNQ25_RS02140	COG1121	(ABC) transporter
HNQ25_RS02145	COG0735	belongs to the Fur family
HNQ25_RS02150	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HNQ25_RS02155	COG2814	Major facilitator Superfamily
HNQ25_RS02160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HNQ25_RS02190	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HNQ25_RS02195	COG0583	DNA-binding transcription factor activity
HNQ25_RS02200	COG0439	Biotin carboxylase
HNQ25_RS02205	COG5016	pyruvate
HNQ25_RS02205	COG0511	ligase activity, forming carbon-carbon bonds
HNQ25_RS02225	COG1070	Carbohydrate kinase
HNQ25_RS02235	COG0246	Mannitol dehydrogenase
HNQ25_RS02250	COG1175	transmembrane transport
HNQ25_RS02275	COG2207	Transcriptional regulator
HNQ25_RS02300	COG0339	signal peptide processing
HNQ25_RS02305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HNQ25_RS02340	COG1764	response to oxidative stress
HNQ25_RS02345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNQ25_RS02370	COG0251	oxidation-reduction process
HNQ25_RS02375	COG2358	TRAP transporter, solute receptor (TAXI family
HNQ25_RS02455	COG0583	DNA-binding transcription factor activity
HNQ25_RS02460	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS02505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HNQ25_RS02510	COG1684	flagellar biosynthetic protein fliR
HNQ25_RS02515	COG1987	bacterial-type flagellum assembly
HNQ25_RS02550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HNQ25_RS02580	COG3161	chorismate lyase activity
HNQ25_RS02585	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HNQ25_RS02600	COG1253	flavin adenine dinucleotide binding
HNQ25_RS02635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNQ25_RS02640	COG0583	DNA-binding transcription factor activity
HNQ25_RS02650	COG2207	Transcriptional regulator
HNQ25_RS02650	COG1917	Cupin 2, conserved barrel domain protein
HNQ25_RS02675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNQ25_RS02680	COG1758	RNA polymerase activity
HNQ25_RS02690	COG1561	YicC-like family, N-terminal region
HNQ25_RS02695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HNQ25_RS02710	COG0708	Exodeoxyribonuclease III
HNQ25_RS02725	COG0824	Thioesterase
HNQ25_RS02730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HNQ25_RS02740	COG0756	dUTP diphosphatase activity
HNQ25_RS02745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNQ25_RS02750	COG2003	Belongs to the UPF0758 family
HNQ25_RS02755	COG0747	negative chemotaxis
HNQ25_RS02760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HNQ25_RS02765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HNQ25_RS02775	COG5001	Diguanylate cyclase
HNQ25_RS02775	COG5002	protein histidine kinase activity
HNQ25_RS02780	COG1252	NADH dehydrogenase
HNQ25_RS02790	COG0174	glutamine synthetase
HNQ25_RS02795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS02855	COG4208	sulfate ABC transporter
HNQ25_RS02865	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HNQ25_RS02870	COG5583	Uncharacterized small protein (DUF2292)
HNQ25_RS02910	COG0583	DNA-binding transcription factor activity
HNQ25_RS02920	COG3842	ATPase activity
HNQ25_RS02925	COG4221	oxidoreductase activity
HNQ25_RS02925	COG0604	alcohol dehydrogenase
HNQ25_RS02925	COG3321	synthase
HNQ25_RS02925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNQ25_RS02935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HNQ25_RS02945	COG0583	DNA-binding transcription factor activity
HNQ25_RS02960	COG1177	transmembrane transport
HNQ25_RS02975	COG2072	flavoprotein involved in K transport
HNQ25_RS02980	COG1304	FMN binding
HNQ25_RS02985	COG2207	Transcriptional regulator
HNQ25_RS02990	COG2223	nitrite transmembrane transporter activity
HNQ25_RS03025	COG2897	thiosulfate sulfurtransferase activity
HNQ25_RS03035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNQ25_RS03045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNQ25_RS03050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNQ25_RS03080	COG2814	Major facilitator Superfamily
HNQ25_RS03095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNQ25_RS03120	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HNQ25_RS03125	COG2205	protein histidine kinase activity
HNQ25_RS03130	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS03135	COG0456	acetyltransferase
HNQ25_RS03140	COG0450	alkyl hydroperoxide reductase
HNQ25_RS03145	COG0431	NADPH-dependent FMN reductase
HNQ25_RS03150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNQ25_RS03155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNQ25_RS03160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNQ25_RS03165	COG1116	anion transmembrane transporter activity
HNQ25_RS03175	COG4150	thiosulfate binding
HNQ25_RS03185	COG4208	sulfate ABC transporter
HNQ25_RS03195	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS03200	COG5002	protein histidine kinase activity
HNQ25_RS03205	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS03220	COG2199	diguanylate cyclase activity
HNQ25_RS03245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNQ25_RS03255	COG1522	sequence-specific DNA binding
HNQ25_RS03305	COG1088	dTDP-glucose 4,6-dehydratase activity
HNQ25_RS03325	COG4215	(ABC) transporter
HNQ25_RS03345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HNQ25_RS03350	COG1194	a g-specific adenine glycosylase
HNQ25_RS03360	COG2223	nitrite transmembrane transporter activity
HNQ25_RS03365	COG0131	Imidazoleglycerol-phosphate dehydratase
HNQ25_RS03380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HNQ25_RS03385	COG0107	imidazoleglycerol-phosphate synthase activity
HNQ25_RS03405	COG0793	Belongs to the peptidase S41A family
HNQ25_RS03410	COG4942	peptidase
HNQ25_RS03415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNQ25_RS03430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HNQ25_RS03435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HNQ25_RS03460	COG2267	carboxylic ester hydrolase activity
HNQ25_RS03475	COG1683	Conserved Protein
HNQ25_RS03480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HNQ25_RS03485	COG0277	FAD linked oxidase domain protein
HNQ25_RS03490	COG0179	Fumarylacetoacetate (FAA) hydrolase
HNQ25_RS03495	COG3204	pilus organization
HNQ25_RS03500	COG3111	PFAM Bacterial OB fold (BOF) protein
HNQ25_RS03505	COG3204	pilus organization
HNQ25_RS03515	COG0789	Transcriptional regulator
HNQ25_RS03535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNQ25_RS03550	COG0494	nUDIX hydrolase
HNQ25_RS03555	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HNQ25_RS03565	COG0730	response to heat
HNQ25_RS03570	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNQ25_RS03575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNQ25_RS03580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNQ25_RS03590	COG0584	glycerophosphoryl diester phosphodiesterase
HNQ25_RS03620	COG2201	protein-glutamate methylesterase activity
HNQ25_RS03625	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HNQ25_RS03630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HNQ25_RS03635	COG0835	chemotaxis
HNQ25_RS03645	COG0835	chemotaxis
HNQ25_RS03650	COG2198	Histidine kinase
HNQ25_RS03650	COG0643	Histidine kinase
HNQ25_RS03670	COG2197	response regulator
HNQ25_RS03675	COG4585	Histidine kinase
HNQ25_RS03680	COG1177	transmembrane transport
HNQ25_RS03685	COG1176	ABC-type spermidine putrescine transport system, permease component I
HNQ25_RS03695	COG3842	ATPase activity
HNQ25_RS03700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HNQ25_RS03710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HNQ25_RS03735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HNQ25_RS03740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNQ25_RS03750	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HNQ25_RS03770	COG0429	hydrolase of the alpha beta-hydrolase fold
HNQ25_RS03780	COG0742	ribosomal rna small subunit methyltransferase
HNQ25_RS03785	COG0612	Peptidase, M16
HNQ25_RS03790	COG0612	Peptidase, M16
HNQ25_RS03795	COG0552	protein localization to endoplasmic reticulum
HNQ25_RS03800	COG2884	Cell division ATP-binding protein ftsE
HNQ25_RS03805	COG2177	Part of the ABC transporter FtsEX involved in
HNQ25_RS03820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNQ25_RS03825	COG2363	Small membrane protein
HNQ25_RS03835	COG2022	thiamine diphosphate biosynthetic process
HNQ25_RS03840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HNQ25_RS03850	COG0563	adenylate kinase activity
HNQ25_RS03860	COG3706	GGDEF domain
HNQ25_RS03865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HNQ25_RS03880	COG2813	Specifically methylates the guanine in position
HNQ25_RS03880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HNQ25_RS03885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HNQ25_RS03890	COG1160	GTP binding
HNQ25_RS03895	COG1872	DUF167
HNQ25_RS03945	COG3852	Histidine kinase
HNQ25_RS03965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNQ25_RS03965	COG0301	tRNA thio-modification
HNQ25_RS03970	COG1217	gtp-binding protein TYPA
HNQ25_RS03980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNQ25_RS03980	COG1017	nitric oxide dioxygenase activity
HNQ25_RS03995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNQ25_RS04025	COG1063	alcohol dehydrogenase
HNQ25_RS04035	COG4191	Histidine kinase
HNQ25_RS04040	COG1126	abc transporter atp-binding protein
HNQ25_RS04045	COG0765	amino acid transport
HNQ25_RS04050	COG0765	amino acid transport
HNQ25_RS04060	COG0204	Acyl-transferase
HNQ25_RS04085	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS04090	COG2205	protein histidine kinase activity
HNQ25_RS04095	COG3755	Protein conserved in bacteria
HNQ25_RS04130	COG4452	Inner membrane protein CreD
HNQ25_RS04150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNQ25_RS04160	COG0826	peptidase U32
HNQ25_RS04165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HNQ25_RS04175	COG1368	sulfuric ester hydrolase activity
HNQ25_RS04180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HNQ25_RS04200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HNQ25_RS04205	COG2005	Transcriptional regulator
HNQ25_RS04205	COG3585	molybdate ion transport
HNQ25_RS04220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HNQ25_RS04225	COG0156	8-amino-7-oxononanoate synthase activity
HNQ25_RS04230	COG1073	alpha beta
HNQ25_RS04230	COG2226	methyltransferase
HNQ25_RS04255	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS04260	COG3706	GGDEF domain
HNQ25_RS04265	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS04280	COG1228	amidohydrolase
HNQ25_RS04285	COG0010	Belongs to the arginase family
HNQ25_RS04290	COG3314	Sporulation integral membrane protein YlbJ
HNQ25_RS04305	COG2188	Transcriptional regulator
HNQ25_RS04320	COG1309	transcriptional regulator
HNQ25_RS04325	COG0431	NADPH-dependent FMN reductase
HNQ25_RS04340	COG0010	Belongs to the arginase family
HNQ25_RS04350	COG2610	gluconate transmembrane transporter activity
HNQ25_RS04360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HNQ25_RS04370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HNQ25_RS04385	COG2205	protein histidine kinase activity
HNQ25_RS04385	COG2202	Pas domain
HNQ25_RS04390	COG2197	response regulator
HNQ25_RS04405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HNQ25_RS04430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HNQ25_RS04440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HNQ25_RS04440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HNQ25_RS04450	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS04455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HNQ25_RS04465	COG2271	Major facilitator Superfamily
HNQ25_RS04475	COG1309	transcriptional regulator
HNQ25_RS04505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HNQ25_RS04510	COG0358	DNA primase activity
HNQ25_RS04515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HNQ25_RS04520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNQ25_RS04525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HNQ25_RS04530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNQ25_RS04540	COG0617	tRNA 3'-terminal CCA addition
HNQ25_RS04545	COG2719	SpoVR family
HNQ25_RS04550	COG2718	Belongs to the UPF0229 family
HNQ25_RS04555	COG2766	serine protein kinase
HNQ25_RS04560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNQ25_RS04565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HNQ25_RS04570	COG2967	ApaG domain
HNQ25_RS04575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HNQ25_RS04580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HNQ25_RS04590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HNQ25_RS04595	COG3178	'Phosphotransferase
HNQ25_RS04600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HNQ25_RS04620	COG2197	response regulator
HNQ25_RS04625	COG3842	ATPase activity
HNQ25_RS04635	COG1176	ABC-type spermidine putrescine transport system, permease component I
HNQ25_RS04650	COG1454	alcohol dehydrogenase
HNQ25_RS04655	COG0659	secondary active sulfate transmembrane transporter activity
HNQ25_RS04665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HNQ25_RS04680	COG0512	Glutamine amidotransferase of anthranilate synthase
HNQ25_RS04685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HNQ25_RS04690	COG0134	indole-3-glycerol-phosphate synthase activity
HNQ25_RS04700	COG1765	OsmC-like protein
HNQ25_RS04705	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HNQ25_RS04710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HNQ25_RS04715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNQ25_RS04740	COG1981	membrane
HNQ25_RS04745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HNQ25_RS04760	COG0316	Belongs to the HesB IscA family
HNQ25_RS04765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HNQ25_RS04770	COG0739	heme binding
HNQ25_RS04775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNQ25_RS04805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HNQ25_RS04805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HNQ25_RS04810	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HNQ25_RS04835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNQ25_RS04855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNQ25_RS04860	COG0081	regulation of translation
HNQ25_RS04865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNQ25_RS04870	COG0222	ribosome binding
HNQ25_RS04875	COG0085	RNA polymerase activity
HNQ25_RS04880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNQ25_RS04885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNQ25_RS04890	COG0049	tRNA binding
HNQ25_RS04895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNQ25_RS04900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNQ25_RS04905	COG0051	transcription antitermination factor activity, RNA binding
HNQ25_RS04910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNQ25_RS04915	COG0088	Forms part of the polypeptide exit tunnel
HNQ25_RS04920	COG0089	rRNA binding
HNQ25_RS04925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNQ25_RS04930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNQ25_RS04935	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNQ25_RS04940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNQ25_RS04945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNQ25_RS04950	COG0255	Belongs to the universal ribosomal protein uL29 family
HNQ25_RS04955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNQ25_RS04960	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNQ25_RS04965	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNQ25_RS04970	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNQ25_RS04975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNQ25_RS04980	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNQ25_RS04985	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNQ25_RS04990	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNQ25_RS04995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNQ25_RS05000	COG1841	ribosomal large subunit assembly
HNQ25_RS05005	COG0200	Binds to the 23S rRNA
HNQ25_RS05015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HNQ25_RS05020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNQ25_RS05025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNQ25_RS05030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNQ25_RS05035	COG0202	RNA polymerase activity
HNQ25_RS05040	COG0203	ribosomal protein L17
HNQ25_RS05045	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HNQ25_RS05060	COG2814	Major facilitator Superfamily
HNQ25_RS05065	COG0629	single-stranded DNA binding
HNQ25_RS05080	COG3047	cAMP biosynthetic process
HNQ25_RS05090	COG0811	peptide transport
HNQ25_RS05095	COG0811	peptide transport
HNQ25_RS05100	COG0848	biopolymer transport protein
HNQ25_RS05125	COG4181	ATPase activity
HNQ25_RS05140	COG3118	belongs to the thioredoxin family
HNQ25_RS05145	COG2264	protein methyltransferase activity
HNQ25_RS05155	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNQ25_RS05160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNQ25_RS05160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HNQ25_RS05175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HNQ25_RS05185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HNQ25_RS05190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HNQ25_RS05200	COG3577	Aspartyl protease
HNQ25_RS05205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HNQ25_RS05215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNQ25_RS05220	COG4206	TonB-dependent receptor
HNQ25_RS05225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HNQ25_RS05230	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HNQ25_RS05240	COG0142	geranyltranstransferase activity
HNQ25_RS05245	COG1722	exodeoxyribonuclease VII activity
HNQ25_RS05250	COG0730	response to heat
HNQ25_RS05290	COG0583	DNA-binding transcription factor activity
HNQ25_RS05295	COG3485	protocatechuate 3,4-dioxygenase
HNQ25_RS05300	COG3485	protocatechuate 3,4-dioxygenase
HNQ25_RS05305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HNQ25_RS05315	COG1414	Transcriptional regulator
HNQ25_RS05320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNQ25_RS05325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HNQ25_RS05340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HNQ25_RS05345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNQ25_RS05350	COG1053	succinate dehydrogenase
HNQ25_RS05355	COG0840	transmembrane signaling receptor activity
HNQ25_RS05385	COG0673	inositol 2-dehydrogenase activity
HNQ25_RS05400	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HNQ25_RS05400	COG1082	Xylose isomerase domain protein TIM barrel
HNQ25_RS05405	COG1309	transcriptional regulator
HNQ25_RS05410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNQ25_RS05415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HNQ25_RS05420	COG2203	Gaf domain
HNQ25_RS05420	COG3706	GGDEF domain
HNQ25_RS05420	COG4251	negative regulation of phosphorylation
HNQ25_RS05420	COG5001	Diguanylate cyclase
HNQ25_RS05445	COG0835	chemotaxis
HNQ25_RS05460	COG3228	Belongs to the MtfA family
HNQ25_RS05470	COG0456	acetyltransferase
HNQ25_RS05485	COG2271	Major facilitator Superfamily
HNQ25_RS05490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HNQ25_RS05500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HNQ25_RS05520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNQ25_RS05525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNQ25_RS05535	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS05550	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS05550	COG4191	Histidine kinase
HNQ25_RS05550	COG2205	protein histidine kinase activity
HNQ25_RS05555	COG4566	intracellular signal transduction
HNQ25_RS05570	COG0702	epimerase
HNQ25_RS05590	COG1346	cytolysis
HNQ25_RS05600	COG0586	Pfam SNARE associated Golgi protein
HNQ25_RS05610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HNQ25_RS05615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNQ25_RS05625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNQ25_RS05630	COG0768	penicillin binding
HNQ25_RS05635	COG0772	Belongs to the SEDS family
HNQ25_RS05640	COG2951	lytic endotransglycosylase activity
HNQ25_RS05650	COG1686	Belongs to the peptidase S11 family
HNQ25_RS05655	COG2921	Belongs to the UPF0250 family
HNQ25_RS05660	COG0321	lipoyl(octanoyl) transferase activity
HNQ25_RS05665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HNQ25_RS05670	COG2951	lytic endotransglycosylase activity
HNQ25_RS05680	COG1466	dna polymerase III delta subunit
HNQ25_RS05690	COG0495	leucyl-tRNA aminoacylation
HNQ25_RS05700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HNQ25_RS05705	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HNQ25_RS05710	COG4535	Mg2 and Co2 transporter CorC
HNQ25_RS05715	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNQ25_RS05720	COG1702	phosphate starvation-inducible protein PhoH
HNQ25_RS05725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HNQ25_RS05745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HNQ25_RS05750	COG0352	thiamine-phosphate diphosphorylase activity
HNQ25_RS05755	COG0352	thiamine-phosphate diphosphorylase activity
HNQ25_RS05755	COG0351	phosphomethylpyrimidine kinase
HNQ25_RS05755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HNQ25_RS05770	COG1120	ATPase activity
HNQ25_RS05780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNQ25_RS05795	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS05815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNQ25_RS05825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNQ25_RS05830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS05840	COG1064	alcohol dehydrogenase
HNQ25_RS05860	COG1522	sequence-specific DNA binding
HNQ25_RS05875	COG1643	Atp-dependent helicase
HNQ25_RS05880	COG0642	Histidine kinase
HNQ25_RS05895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HNQ25_RS05905	COG2863	cytochrome
HNQ25_RS05910	COG3258	Cytochrome c
HNQ25_RS05955	COG2176	DNA-directed DNA polymerase activity
HNQ25_RS05960	COG0513	Belongs to the DEAD box helicase family
HNQ25_RS05975	COG2201	protein-glutamate methylesterase activity
HNQ25_RS05980	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
HNQ25_RS05990	COG0123	including yeast histone deacetylase and acetoin utilization protein
HNQ25_RS06000	COG1272	protein, Hemolysin III
HNQ25_RS06005	COG0519	Catalyzes the synthesis of GMP from XMP
HNQ25_RS06015	COG1946	Acyl-CoA thioesterase
HNQ25_RS06020	COG0546	phosphoglycolate phosphatase activity
HNQ25_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS06075	COG0583	DNA-binding transcription factor activity
HNQ25_RS06105	COG0583	DNA-binding transcription factor activity
HNQ25_RS06110	COG0596	Alpha beta hydrolase
HNQ25_RS06115	COG0066	3-isopropylmalate dehydratase activity
HNQ25_RS06120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNQ25_RS06135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNQ25_RS06160	COG1079	Belongs to the binding-protein-dependent transport system permease family
HNQ25_RS06165	COG4603	Belongs to the binding-protein-dependent transport system permease family
HNQ25_RS06170	COG3845	ABC transporter
HNQ25_RS06180	COG2153	protein acetylation
HNQ25_RS06200	COG1309	transcriptional regulator
HNQ25_RS06205	COG0840	transmembrane signaling receptor activity
HNQ25_RS06255	COG0659	secondary active sulfate transmembrane transporter activity
HNQ25_RS06275	COG3642	lipopolysaccharide core region biosynthetic process
HNQ25_RS06280	COG0459	protein refolding
HNQ25_RS06285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNQ25_RS06290	COG3030	protein affecting phage T7 exclusion by the F plasmid
HNQ25_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS06305	COG0142	geranyltranstransferase activity
HNQ25_RS06310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HNQ25_RS06315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HNQ25_RS06320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNQ25_RS06325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNQ25_RS06330	COG3045	CreA protein
HNQ25_RS06380	COG0840	transmembrane signaling receptor activity
HNQ25_RS06385	COG0501	Belongs to the peptidase M48B family
HNQ25_RS06395	COG2119	membrane
HNQ25_RS06400	COG2813	Specifically methylates the guanine in position
HNQ25_RS06405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNQ25_RS06410	COG1280	lysine exporter protein (LysE YggA)
HNQ25_RS06415	COG0183	Belongs to the thiolase family
HNQ25_RS06420	COG0318	PFAM AMP-dependent synthetase and ligase
HNQ25_RS06455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNQ25_RS06460	COG2885	chlorophyll binding
HNQ25_RS06465	COG2885	chlorophyll binding
HNQ25_RS06480	COG0204	Acyl-transferase
HNQ25_RS06490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNQ25_RS06500	COG1047	Peptidyl-prolyl cis-trans
HNQ25_RS06505	COG0386	Belongs to the glutathione peroxidase family
HNQ25_RS06520	COG0277	FAD linked oxidase domain protein
HNQ25_RS06525	COG1304	FMN binding
HNQ25_RS06530	COG1620	l-lactate permease
HNQ25_RS06535	COG2186	Transcriptional regulator
HNQ25_RS06540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HNQ25_RS06545	COG0733	neurotransmitter:sodium symporter activity
HNQ25_RS06555	COG2914	Belongs to the UPF0125 (RnfH) family
HNQ25_RS06560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HNQ25_RS06570	COG0497	DNA recombination
HNQ25_RS06575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNQ25_RS06580	COG0443	Heat shock 70 kDa protein
HNQ25_RS06585	COG0484	heat shock protein binding
HNQ25_RS06590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HNQ25_RS06605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HNQ25_RS06620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HNQ25_RS06630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HNQ25_RS06635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNQ25_RS06640	COG0149	triose-phosphate isomerase activity
HNQ25_RS06645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HNQ25_RS06660	COG0779	Required for maturation of 30S ribosomal subunits
HNQ25_RS06665	COG0195	Participates in both transcription termination and antitermination
HNQ25_RS06670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNQ25_RS06675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNQ25_RS06680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNQ25_RS06685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNQ25_RS06690	COG1185	polyribonucleotide nucleotidyltransferase activity
HNQ25_RS06720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HNQ25_RS06720	COG0116	Belongs to the methyltransferase superfamily
HNQ25_RS06735	COG0166	Belongs to the GPI family
HNQ25_RS06740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HNQ25_RS06745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HNQ25_RS06755	COG0617	tRNA 3'-terminal CCA addition
HNQ25_RS06765	COG4191	Histidine kinase
HNQ25_RS06775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNQ25_RS06780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNQ25_RS06785	COG0436	Aminotransferase
HNQ25_RS06790	COG1489	DNA binding
HNQ25_RS06805	COG3720	iron ion transport
HNQ25_RS06810	COG4558	Periplasmic binding protein
HNQ25_RS06815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNQ25_RS06855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HNQ25_RS06865	COG3098	single-species biofilm formation
HNQ25_RS06875	COG0028	Belongs to the TPP enzyme family
HNQ25_RS06890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HNQ25_RS06895	COG1183	phosphatidylcholine synthase activity
HNQ25_RS06900	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HNQ25_RS06905	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HNQ25_RS06935	COG2995	paraquat-inducible protein a
HNQ25_RS06940	COG2995	paraquat-inducible protein a
HNQ25_RS06945	COG3008	intermembrane lipid transfer
HNQ25_RS06965	COG0019	diaminopimelate decarboxylase activity
HNQ25_RS06975	COG2851	Citrate transporter
HNQ25_RS06990	COG0583	DNA-binding transcription factor activity
HNQ25_RS07000	COG0456	acetyltransferase
HNQ25_RS07020	COG3604	Transcriptional regulator
HNQ25_RS07025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HNQ25_RS07030	COG0545	Peptidyl-prolyl cis-trans isomerase
HNQ25_RS07040	COG0417	DNA replication proofreading
HNQ25_RS07045	COG0861	Integral membrane protein TerC family
HNQ25_RS07055	COG1971	Probably functions as a manganese efflux pump
HNQ25_RS07085	COG3706	GGDEF domain
HNQ25_RS07090	COG0318	PFAM AMP-dependent synthetase and ligase
HNQ25_RS07095	COG0400	carboxylic ester hydrolase activity
HNQ25_RS07100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNQ25_RS07105	COG4597	amino acid ABC transporter
HNQ25_RS07110	COG0765	amino acid transport
HNQ25_RS07115	COG1126	abc transporter atp-binding protein
HNQ25_RS07150	COG3081	Nucleoid-associated protein
HNQ25_RS07160	COG0531	amino acid
HNQ25_RS07165	COG1522	sequence-specific DNA binding
HNQ25_RS07170	COG0420	3'-5' exonuclease activity
HNQ25_RS07190	COG3547	Transposase (IS116 IS110 IS902 family)
HNQ25_RS07220	COG0583	DNA-binding transcription factor activity
HNQ25_RS07225	COG1301	dicarboxylic acid transport
HNQ25_RS07230	COG1794	racemase activity, acting on amino acids and derivatives
HNQ25_RS07245	COG0583	DNA-binding transcription factor activity
HNQ25_RS07250	COG0419	ATPase involved in DNA repair
HNQ25_RS07255	COG1335	isochorismatase
HNQ25_RS07270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNQ25_RS07275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HNQ25_RS07280	COG0471	metal ion transport
HNQ25_RS07280	COG0490	domain, Protein
HNQ25_RS07290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HNQ25_RS07295	COG1757	Na H antiporter
HNQ25_RS07315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HNQ25_RS07320	COG0795	lipopolysaccharide-transporting ATPase activity
HNQ25_RS07325	COG0795	lipopolysaccharide-transporting ATPase activity
HNQ25_RS07335	COG1278	Cold shock
HNQ25_RS07350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HNQ25_RS07360	COG1862	Preprotein translocase
HNQ25_RS07375	COG3134	Outer membrane lipoprotein
HNQ25_RS07390	COG1045	serine acetyltransferase
HNQ25_RS07400	COG1104	cysteine desulfurase activity
HNQ25_RS07410	COG0316	Belongs to the HesB IscA family
HNQ25_RS07415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HNQ25_RS07420	COG0443	Heat shock 70 kDa protein
HNQ25_RS07425	COG0633	Ferredoxin
HNQ25_RS07435	COG0105	UTP biosynthetic process
HNQ25_RS07440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HNQ25_RS07455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HNQ25_RS07460	COG0124	histidyl-tRNA synthetase
HNQ25_RS07475	COG1160	GTP binding
HNQ25_RS07480	COG0436	Aminotransferase
HNQ25_RS07495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNQ25_RS07500	COG0625	glutathione transferase activity
HNQ25_RS07505	COG0668	transmembrane transport
HNQ25_RS07510	COG0739	heme binding
HNQ25_RS07515	COG1570	exodeoxyribonuclease VII activity
HNQ25_RS07545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HNQ25_RS07545	COG0519	Catalyzes the synthesis of GMP from XMP
HNQ25_RS07575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HNQ25_RS07580	COG0047	phosphoribosylformylglycinamidine synthase activity
HNQ25_RS07580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNQ25_RS07595	COG3034	peptidoglycan biosynthetic process
HNQ25_RS07605	COG0494	nUDIX hydrolase
HNQ25_RS07620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HNQ25_RS07630	COG4536	flavin adenine dinucleotide binding
HNQ25_RS07635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HNQ25_RS07640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNQ25_RS07645	COG0228	four-way junction DNA binding
HNQ25_RS07650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNQ25_RS07655	COG0336	Belongs to the RNA methyltransferase TrmD family
HNQ25_RS07660	COG0335	large ribosomal subunit rRNA binding
HNQ25_RS07665	COG1607	acyl-coa hydrolase
HNQ25_RS07680	COG1764	response to oxidative stress
HNQ25_RS07685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HNQ25_RS07710	COG1842	Phage shock protein A
HNQ25_RS07725	COG2255	four-way junction helicase activity
HNQ25_RS07745	COG0366	Alpha amylase catalytic
HNQ25_RS07760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNQ25_RS07770	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HNQ25_RS07785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HNQ25_RS07810	COG1073	alpha beta
HNQ25_RS07820	COG2885	chlorophyll binding
HNQ25_RS07835	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNQ25_RS07840	COG0563	adenylate kinase activity
HNQ25_RS07850	COG1214	PFAM Peptidase M22, glycoprotease
HNQ25_RS07860	COG1801	Protein of unknown function DUF72
HNQ25_RS07875	COG0742	ribosomal rna small subunit methyltransferase
HNQ25_RS07880	COG1309	transcriptional regulator
HNQ25_RS07885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS07910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNQ25_RS07915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HNQ25_RS07930	COG3842	ATPase activity
HNQ25_RS07940	COG0243	molybdopterin cofactor binding
HNQ25_RS07945	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HNQ25_RS07985	COG2205	protein histidine kinase activity
HNQ25_RS08005	COG1704	LemA family
HNQ25_RS08020	COG0004	ammonium transporteR
HNQ25_RS08040	COG0714	Associated with various cellular activities
HNQ25_RS08070	COG2925	Exonuclease
HNQ25_RS08080	COG0788	formyltetrahydrofolate deformylase activity
HNQ25_RS08085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HNQ25_RS08085	COG0517	IMP dehydrogenase activity
HNQ25_RS08085	COG0617	tRNA 3'-terminal CCA addition
HNQ25_RS08100	COG0433	COG0433 Predicted ATPase
HNQ25_RS08145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNQ25_RS08150	COG1609	Transcriptional regulator
HNQ25_RS08170	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HNQ25_RS08195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNQ25_RS08215	COG0789	Transcriptional regulator
HNQ25_RS08225	COG1366	Belongs to the anti-sigma-factor antagonist family
HNQ25_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS08260	COG0693	protein deglycase activity
HNQ25_RS08270	COG0642	Histidine kinase
HNQ25_RS08285	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS08295	COG0318	PFAM AMP-dependent synthetase and ligase
HNQ25_RS08315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNQ25_RS08320	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HNQ25_RS08340	COG0252	asparaginase activity
HNQ25_RS08345	COG1115	amino acid carrier protein
HNQ25_RS08350	COG3048	D-serine ammonia-lyase activity
HNQ25_RS08360	COG3706	GGDEF domain
HNQ25_RS08370	COG1024	Enoyl-CoA hydratase
HNQ25_RS08375	COG0583	DNA-binding transcription factor activity
HNQ25_RS08380	COG1335	isochorismatase
HNQ25_RS08385	COG0469	pyruvate kinase activity
HNQ25_RS08390	COG0589	response to stress
HNQ25_RS08440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HNQ25_RS08450	COG1472	Belongs to the glycosyl hydrolase 3 family
HNQ25_RS08460	COG2943	transferase activity, transferring hexosyl groups
HNQ25_RS08465	COG3038	cytochrome b561
HNQ25_RS08470	COG2814	Major facilitator Superfamily
HNQ25_RS08475	COG0583	DNA-binding transcription factor activity
HNQ25_RS08480	COG0210	DNA helicase
HNQ25_RS08485	COG0697	spore germination
HNQ25_RS08490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS08490	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HNQ25_RS08500	COG0183	Belongs to the thiolase family
HNQ25_RS08510	COG0583	DNA-binding transcription factor activity
HNQ25_RS08520	COG0625	glutathione transferase activity
HNQ25_RS08525	COG1017	nitric oxide dioxygenase activity
HNQ25_RS08525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HNQ25_RS08545	COG2207	Transcriptional regulator
HNQ25_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS08565	COG1902	pentaerythritol trinitrate reductase activity
HNQ25_RS08565	COG0446	pyridine nucleotide-disulphide oxidoreductase
HNQ25_RS08575	COG4221	oxidoreductase activity
HNQ25_RS08580	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HNQ25_RS08600	COG0604	alcohol dehydrogenase
HNQ25_RS08605	COG0789	Transcriptional regulator
HNQ25_RS08615	COG2207	Transcriptional regulator
HNQ25_RS08670	COG3639	organic phosphonate transmembrane transporter activity
HNQ25_RS08680	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HNQ25_RS08685	COG0709	Synthesizes selenophosphate from selenide and ATP
HNQ25_RS08690	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HNQ25_RS08695	COG2084	Dehydrogenase
HNQ25_RS08700	COG3622	Belongs to the hyi family
HNQ25_RS08715	COG2271	Major facilitator Superfamily
HNQ25_RS08730	COG2133	pyrroloquinoline quinone binding
HNQ25_RS08740	COG2996	Protein conserved in bacteria
HNQ25_RS08755	COG3706	GGDEF domain
HNQ25_RS08765	COG0631	protein serine/threonine phosphatase activity
HNQ25_RS08790	COG0217	transcriptional regulatory protein
HNQ25_RS08795	COG2084	Dehydrogenase
HNQ25_RS08815	COG4251	negative regulation of phosphorylation
HNQ25_RS08815	COG5001	Diguanylate cyclase
HNQ25_RS08815	COG2203	Gaf domain
HNQ25_RS08815	COG3706	GGDEF domain
HNQ25_RS08820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNQ25_RS08845	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNQ25_RS08855	COG0826	peptidase U32
HNQ25_RS08860	COG3318	Belongs to the UPF0149 family
HNQ25_RS08860	COG3012	SEC-C Motif Domain Protein
HNQ25_RS08870	COG4574	serine-type endopeptidase inhibitor activity
HNQ25_RS08890	COG1999	signal sequence binding
HNQ25_RS08910	COG2226	methyltransferase
HNQ25_RS08915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNQ25_RS08920	COG0583	DNA-binding transcription factor activity
HNQ25_RS08930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HNQ25_RS08955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNQ25_RS08960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNQ25_RS08960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNQ25_RS08965	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS08970	COG2205	protein histidine kinase activity
HNQ25_RS08985	COG2076	Multidrug Resistance protein
HNQ25_RS08990	COG0385	Bile acid
HNQ25_RS08995	COG1737	Transcriptional regulator
HNQ25_RS09010	COG0800	Aldolase
HNQ25_RS09015	COG0840	transmembrane signaling receptor activity
HNQ25_RS09025	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HNQ25_RS09050	COG2154	pterin-4-alpha-carbinolamine dehydratase
HNQ25_RS09065	COG0590	tRNA wobble adenosine to inosine editing
HNQ25_RS09070	COG0583	DNA-binding transcription factor activity
HNQ25_RS09075	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HNQ25_RS09080	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS09085	COG2079	MmgE PrpD family protein
HNQ25_RS09090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HNQ25_RS09095	COG2301	Belongs to the HpcH HpaI aldolase family
HNQ25_RS09105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNQ25_RS09110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HNQ25_RS09115	COG0583	DNA-binding transcription factor activity
HNQ25_RS09145	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HNQ25_RS09165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNQ25_RS09170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS09200	COG4991	sh3 domain protein
HNQ25_RS09210	COG3278	Belongs to the heme-copper respiratory oxidase family
HNQ25_RS09240	COG1653	transport
HNQ25_RS09245	COG1175	transmembrane transport
HNQ25_RS09250	COG0395	ABC-type sugar transport system, permease component
HNQ25_RS09255	COG3842	ATPase activity
HNQ25_RS09260	COG4580	involved in the transport of maltose and maltodextrins
HNQ25_RS09265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS09295	COG1346	cytolysis
HNQ25_RS09310	COG2937	Belongs to the GPAT DAPAT family
HNQ25_RS09335	COG1278	Cold shock
HNQ25_RS09345	COG2226	methyltransferase
HNQ25_RS09350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HNQ25_RS09355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HNQ25_RS09365	COG4807	Protein conserved in bacteria
HNQ25_RS09380	COG2171	N-acyltransferase activity
HNQ25_RS09385	COG1393	Belongs to the ArsC family
HNQ25_RS09390	COG0025	NhaP-type Na H and K H
HNQ25_RS09395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HNQ25_RS09400	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HNQ25_RS09405	COG0024	Methionine aminopeptidase
HNQ25_RS09410	COG0052	Belongs to the universal ribosomal protein uS2 family
HNQ25_RS09415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNQ25_RS09420	COG0528	UMP kinase activity
HNQ25_RS09425	COG0233	cytoplasmic translational termination
HNQ25_RS09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNQ25_RS09440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HNQ25_RS09450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HNQ25_RS09460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HNQ25_RS09465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HNQ25_RS09470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HNQ25_RS09475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HNQ25_RS09480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNQ25_RS09490	COG0825	malonyl-CoA metabolic process
HNQ25_RS09495	COG0037	tRNA processing
HNQ25_RS09500	COG0504	CTP synthase activity
HNQ25_RS09505	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HNQ25_RS09510	COG0148	phosphopyruvate hydratase activity
HNQ25_RS09520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HNQ25_RS09535	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HNQ25_RS09545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HNQ25_RS09550	COG0585	pseudouridine synthase activity
HNQ25_RS09555	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HNQ25_RS09560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HNQ25_RS09580	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HNQ25_RS09585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNQ25_RS09595	COG1546	Belongs to the CinA family
HNQ25_RS09605	COG2137	regulation of response to DNA damage stimulus
HNQ25_RS09620	COG0167	dihydroorotate dehydrogenase activity
HNQ25_RS09625	COG3130	regulation of translation
HNQ25_RS09630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HNQ25_RS09630	COG0116	Belongs to the methyltransferase superfamily
HNQ25_RS09635	COG2027	D-alanyl-D-alanine carboxypeptidase
HNQ25_RS09640	COG3171	Protein conserved in bacteria
HNQ25_RS09645	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HNQ25_RS09660	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HNQ25_RS09675	COG4575	ribosome binding
HNQ25_RS09680	COG0004	ammonium transporteR
HNQ25_RS09690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HNQ25_RS09695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HNQ25_RS09705	COG0628	permease
HNQ25_RS09730	COG1295	ribonuclease BN
HNQ25_RS09750	COG2814	Major facilitator Superfamily
HNQ25_RS09780	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS09785	COG1022	Amp-dependent synthetase and ligase
HNQ25_RS09790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HNQ25_RS09795	COG3091	SprT-like family
HNQ25_RS09815	COG0037	tRNA processing
HNQ25_RS09820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HNQ25_RS09830	COG3089	Belongs to the UPF0270 family
HNQ25_RS09840	COG1363	Peptidase, m42
HNQ25_RS09845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNQ25_RS09845	COG0189	ligase activity
HNQ25_RS09850	COG0367	asparagine synthase
HNQ25_RS09885	COG0446	pyridine nucleotide-disulphide oxidoreductase
HNQ25_RS09885	COG1902	pentaerythritol trinitrate reductase activity
HNQ25_RS09895	COG2358	TRAP transporter, solute receptor (TAXI family
HNQ25_RS09910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNQ25_RS09910	COG0425	Belongs to the sulfur carrier protein TusA family
HNQ25_RS09920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNQ25_RS09925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HNQ25_RS09935	COG3139	Protein of unknown function (DUF1315)
HNQ25_RS09945	COG0308	aminopeptidase N
HNQ25_RS09960	COG4447	cellulose binding
HNQ25_RS09995	COG0714	Associated with various cellular activities
HNQ25_RS10000	COG1984	allophanate hydrolase subunit 2
HNQ25_RS10005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HNQ25_RS10010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HNQ25_RS10020	COG0840	transmembrane signaling receptor activity
HNQ25_RS10030	COG0583	DNA-binding transcription factor activity
HNQ25_RS10060	COG0425	Belongs to the sulfur carrier protein TusA family
HNQ25_RS10070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HNQ25_RS10075	COG2716	regulation of RNA biosynthetic process
HNQ25_RS10080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNQ25_RS10085	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HNQ25_RS10090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HNQ25_RS10160	COG1215	transferase activity, transferring glycosyl groups
HNQ25_RS10175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNQ25_RS10180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS10190	COG0583	DNA-binding transcription factor activity
HNQ25_RS10195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNQ25_RS10210	COG0697	spore germination
HNQ25_RS10215	COG1522	sequence-specific DNA binding
HNQ25_RS10235	COG4774	siderophore transport
HNQ25_RS10240	COG1120	ATPase activity
HNQ25_RS10245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNQ25_RS10250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNQ25_RS10255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HNQ25_RS10280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HNQ25_RS10285	COG4615	Cyclic peptide transporter
HNQ25_RS10310	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HNQ25_RS10320	COG0477	Major facilitator Superfamily
HNQ25_RS10325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HNQ25_RS10345	COG0835	chemotaxis
HNQ25_RS10345	COG0784	Response regulator, receiver
HNQ25_RS10350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HNQ25_RS10365	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HNQ25_RS10375	COG4787	bacterial-type flagellum-dependent cell motility
HNQ25_RS10385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HNQ25_RS10390	COG1706	bacterial-type flagellum-dependent cell motility
HNQ25_RS10400	COG1256	bacterial-type flagellum assembly
HNQ25_RS10415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HNQ25_RS10435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HNQ25_RS10465	COG1216	Glycosyl transferase, family 2
HNQ25_RS10465	COG0438	transferase activity, transferring glycosyl groups
HNQ25_RS10475	COG1334	flagellar protein FlaG
HNQ25_RS10485	COG1516	flagellar protein fliS
HNQ25_RS10545	COG2882	bacterial-type flagellum organization
HNQ25_RS10555	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS10635	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HNQ25_RS10640	COG0784	Response regulator, receiver
HNQ25_RS10640	COG2198	Histidine kinase
HNQ25_RS10640	COG0643	Histidine kinase
HNQ25_RS10645	COG2201	protein-glutamate methylesterase activity
HNQ25_RS10650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNQ25_RS10655	COG1360	Flagellar Motor Protein
HNQ25_RS10660	COG1192	Involved in chromosome partitioning
HNQ25_RS10670	COG0835	chemotaxis
HNQ25_RS10690	COG4133	protoheme IX ABC transporter activity
HNQ25_RS10710	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HNQ25_RS10715	COG1138	Cytochrome C-type biogenesis protein
HNQ25_RS10740	COG0471	metal ion transport
HNQ25_RS10745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNQ25_RS10760	COG4413	Urea transporter
HNQ25_RS10765	COG0469	pyruvate kinase activity
HNQ25_RS10775	COG2084	Dehydrogenase
HNQ25_RS10780	COG3622	Belongs to the hyi family
HNQ25_RS10785	COG3960	tartronate-semialdehyde synthase activity
HNQ25_RS10790	COG0583	DNA-binding transcription factor activity
HNQ25_RS10805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HNQ25_RS10815	COG1953	Uracil, thiamine, allantoin
HNQ25_RS10825	COG2233	PERMEase
HNQ25_RS10855	COG2252	PERMEase
HNQ25_RS10860	COG1802	Transcriptional regulator
HNQ25_RS10865	COG0402	S-adenosylhomocysteine deaminase activity
HNQ25_RS10895	COG3115	cell septum assembly
HNQ25_RS10900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNQ25_RS10910	COG0302	gtp cyclohydrolase
HNQ25_RS10945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HNQ25_RS10955	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HNQ25_RS10995	COG0300	oxidoreductase activity
HNQ25_RS11005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HNQ25_RS11005	COG0519	Catalyzes the synthesis of GMP from XMP
HNQ25_RS11045	COG0840	transmembrane signaling receptor activity
HNQ25_RS11055	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HNQ25_RS11075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HNQ25_RS11080	COG0386	Belongs to the glutathione peroxidase family
HNQ25_RS11085	COG1846	Transcriptional regulator
HNQ25_RS11100	COG1956	GAF domain-containing protein
HNQ25_RS11140	COG4890	Cyd operon protein YbgT
HNQ25_RS11145	COG1294	oxidase, subunit
HNQ25_RS11160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNQ25_RS11195	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS11205	COG1131	(ABC) transporter
HNQ25_RS11210	COG0842	Transport permease protein
HNQ25_RS11220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HNQ25_RS11225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HNQ25_RS11225	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HNQ25_RS11255	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS11265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HNQ25_RS11290	COG1012	belongs to the aldehyde dehydrogenase family
HNQ25_RS11300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS11315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HNQ25_RS11320	COG1025	Belongs to the peptidase M16 family
HNQ25_RS11340	COG0784	Response regulator, receiver
HNQ25_RS11340	COG2205	protein histidine kinase activity
HNQ25_RS11365	COG1131	(ABC) transporter
HNQ25_RS11390	COG3851	Histidine kinase
HNQ25_RS11430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HNQ25_RS11470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HNQ25_RS11475	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HNQ25_RS11485	COG0535	radical SAM domain protein
HNQ25_RS11500	COG5002	protein histidine kinase activity
HNQ25_RS11515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS11525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNQ25_RS11535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HNQ25_RS11540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNQ25_RS11545	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNQ25_RS11550	COG0072	phenylalanine-tRNA ligase activity
HNQ25_RS11555	COG0776	regulation of translation
HNQ25_RS11575	COG1555	photosystem II stabilization
HNQ25_RS11580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HNQ25_RS11585	COG1074	ATP-dependent DNA helicase activity
HNQ25_RS11590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HNQ25_RS11620	COG0720	synthase
HNQ25_RS11655	COG0840	transmembrane signaling receptor activity
HNQ25_RS11660	COG2056	Na+-H+ antiporter family
HNQ25_RS11675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNQ25_RS11680	COG0488	(ABC) transporter
HNQ25_RS11685	COG1595	DNA-templated transcription, initiation
HNQ25_RS11695	COG4774	siderophore transport
HNQ25_RS11725	COG2175	clavaminate synthase activity
HNQ25_RS11735	COG1116	anion transmembrane transporter activity
HNQ25_RS11740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNQ25_RS11750	COG1752	Esterase of the alpha-beta hydrolase superfamily
HNQ25_RS11770	COG0640	Transcriptional regulator
HNQ25_RS11775	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HNQ25_RS11785	COG0251	oxidation-reduction process
HNQ25_RS11820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNQ25_RS11835	COG3706	GGDEF domain
HNQ25_RS11840	COG0596	Alpha beta hydrolase
HNQ25_RS11855	COG1024	Enoyl-CoA hydratase
HNQ25_RS11860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HNQ25_RS11865	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS11870	COG0789	Transcriptional regulator
HNQ25_RS11885	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS11895	COG3284	Transcriptional regulator
HNQ25_RS11900	COG3842	ATPase activity
HNQ25_RS11905	COG3842	ATPase activity
HNQ25_RS11915	COG0395	ABC-type sugar transport system, permease component
HNQ25_RS11930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNQ25_RS11950	COG0544	peptidyl-prolyl cis-trans isomerase activity
HNQ25_RS11955	COG0740	serine-type endopeptidase activity
HNQ25_RS11960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNQ25_RS11965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HNQ25_RS11975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HNQ25_RS11980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNQ25_RS11990	COG4172	Belongs to the ABC transporter superfamily
HNQ25_RS11995	COG4239	(ABC) transporter, permease
HNQ25_RS12000	COG4174	ABC transporter (Permease)
HNQ25_RS12010	COG4166	transmembrane transport
HNQ25_RS12020	COG0741	lytic transglycosylase activity
HNQ25_RS12020	COG1388	LysM domain
HNQ25_RS12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNQ25_RS12035	COG0328	RNA-DNA hybrid ribonuclease activity
HNQ25_RS12040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HNQ25_RS12050	COG1024	Enoyl-CoA hydratase
HNQ25_RS12060	COG2816	NAD+ diphosphatase activity
HNQ25_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS12095	COG0616	signal peptide processing
HNQ25_RS12100	COG0604	alcohol dehydrogenase
HNQ25_RS12115	COG3384	dioxygenase
HNQ25_RS12120	COG0500	methyltransferase
HNQ25_RS12125	COG0501	Belongs to the peptidase M48B family
HNQ25_RS12135	COG0436	Aminotransferase
HNQ25_RS12140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNQ25_RS12155	COG3738	Protein conserved in bacteria
HNQ25_RS12160	COG3011	Protein conserved in bacteria
HNQ25_RS12170	COG1132	(ABC) transporter
HNQ25_RS12175	COG5006	permease, DMT superfamily
HNQ25_RS12180	COG3123	guanosine phosphorylase activity
HNQ25_RS12190	COG2084	Dehydrogenase
HNQ25_RS12210	COG2009	succinate dehydrogenase
HNQ25_RS12215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HNQ25_RS12220	COG1053	succinate dehydrogenase
HNQ25_RS12225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HNQ25_RS12245	COG0045	succinate-CoA ligase (ADP-forming) activity
HNQ25_RS12255	COG4772	TonB-dependent receptor
HNQ25_RS12260	COG3265	gluconokinase activity
HNQ25_RS12265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HNQ25_RS12270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HNQ25_RS12275	COG1609	Transcriptional regulator
HNQ25_RS12300	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HNQ25_RS12305	COG4181	ATPase activity
HNQ25_RS12330	COG2610	gluconate transmembrane transporter activity
HNQ25_RS12355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HNQ25_RS12365	COG0589	response to stress
HNQ25_RS12375	COG0175	sulfate reduction
HNQ25_RS12380	COG0560	Phosphoserine phosphatase
HNQ25_RS12390	COG2909	trisaccharide binding
HNQ25_RS12410	COG0189	ligase activity
HNQ25_RS12410	COG4067	protein conserved in archaea
HNQ25_RS12415	COG1802	Transcriptional regulator
HNQ25_RS12440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HNQ25_RS12455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HNQ25_RS12470	COG0668	transmembrane transport
HNQ25_RS12490	COG0243	molybdopterin cofactor binding
HNQ25_RS12495	COG2146	nitrite reductase [NAD(P)H] activity
HNQ25_RS12500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNQ25_RS12515	COG1116	anion transmembrane transporter activity
HNQ25_RS12520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNQ25_RS12525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNQ25_RS12540	COG1024	Enoyl-CoA hydratase
HNQ25_RS12560	COG4974	Belongs to the 'phage' integrase family
HNQ25_RS12635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HNQ25_RS12640	COG1323	Belongs to the UPF0348 family
HNQ25_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS12745	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HNQ25_RS12770	COG1285	pathogenesis
HNQ25_RS12810	COG0058	SHG alpha-glucan phosphorylase activity
HNQ25_RS12820	COG0392	lysyltransferase activity
HNQ25_RS12825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNQ25_RS12830	COG3568	Endonuclease Exonuclease Phosphatase
HNQ25_RS12855	COG1640	4-alpha-glucanotransferase
HNQ25_RS12860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HNQ25_RS12865	COG0297	glycogen (starch) synthase activity
HNQ25_RS12870	COG1058	Belongs to the CinA family
HNQ25_RS12870	COG1546	Belongs to the CinA family
HNQ25_RS12920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HNQ25_RS12925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HNQ25_RS12925	COG2010	Cytochrome c
HNQ25_RS12960	COG1196	nuclear chromosome segregation
HNQ25_RS12965	COG1074	ATP-dependent DNA helicase activity
HNQ25_RS12980	COG0587	DNA-directed DNA polymerase activity
HNQ25_RS12995	COG1252	NADH dehydrogenase
HNQ25_RS13000	COG2207	Transcriptional regulator
HNQ25_RS13010	COG0835	chemotaxis
HNQ25_RS13010	COG0784	Response regulator, receiver
HNQ25_RS13015	COG1063	alcohol dehydrogenase
HNQ25_RS13025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS13075	COG3706	GGDEF domain
HNQ25_RS13075	COG4251	negative regulation of phosphorylation
HNQ25_RS13075	COG2203	Gaf domain
HNQ25_RS13075	COG5001	Diguanylate cyclase
HNQ25_RS13085	COG1278	Cold shock
HNQ25_RS13090	COG1968	undecaprenyl-diphosphatase activity
HNQ25_RS13095	COG0840	transmembrane signaling receptor activity
HNQ25_RS13125	COG2010	Cytochrome c
HNQ25_RS13130	COG0753	catalase activity
HNQ25_RS13140	COG3813	Protein conserved in bacteria
HNQ25_RS13145	COG0316	Belongs to the HesB IscA family
HNQ25_RS13145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HNQ25_RS13150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HNQ25_RS13180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HNQ25_RS13200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HNQ25_RS13220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HNQ25_RS13250	COG0492	ferredoxin-NADP+ reductase activity
HNQ25_RS13255	COG0385	Bile acid
HNQ25_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS13275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HNQ25_RS13280	COG0501	Belongs to the peptidase M48B family
HNQ25_RS13285	COG3755	Protein conserved in bacteria
HNQ25_RS13290	COG3214	Protein conserved in bacteria
HNQ25_RS13310	COG0583	DNA-binding transcription factor activity
HNQ25_RS13320	COG0583	DNA-binding transcription factor activity
HNQ25_RS13325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNQ25_RS13360	COG0322	excinuclease ABC activity
HNQ25_RS13390	COG2168	tRNA wobble position uridine thiolation
HNQ25_RS13395	COG2920	part of a sulfur-relay system
HNQ25_RS13400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HNQ25_RS13405	COG0435	Glutathione S-transferase
HNQ25_RS13410	COG1648	precorrin-2 dehydrogenase activity
HNQ25_RS13410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HNQ25_RS13415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNQ25_RS13420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HNQ25_RS13425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HNQ25_RS13430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HNQ25_RS13435	COG1674	ftsk spoiiie
HNQ25_RS13440	COG0492	ferredoxin-NADP+ reductase activity
HNQ25_RS13445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HNQ25_RS13450	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HNQ25_RS13455	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNQ25_RS13460	COG0542	response to heat
HNQ25_RS13465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HNQ25_RS13470	COG1278	Cold shock
HNQ25_RS13510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS13515	COG0482	sulfurtransferase activity
HNQ25_RS13520	COG2915	High frequency lysogenization protein hflD homolog
HNQ25_RS13535	COG2850	peptidyl-arginine hydroxylation
HNQ25_RS13540	COG2153	protein acetylation
HNQ25_RS13570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HNQ25_RS13575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HNQ25_RS13580	COG0649	NAD binding
HNQ25_RS13580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HNQ25_RS13600	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HNQ25_RS13605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HNQ25_RS13615	COG0713	ATP synthesis coupled electron transport
HNQ25_RS13630	COG1007	ATP synthesis coupled electron transport
HNQ25_RS13635	COG4106	trans-aconitate 2-methyltransferase activity
HNQ25_RS13675	COG2911	Protein conserved in bacteria
HNQ25_RS13680	COG0729	surface antigen
HNQ25_RS13690	COG0708	Exodeoxyribonuclease III
HNQ25_RS13695	COG2885	chlorophyll binding
HNQ25_RS13700	COG0861	Integral membrane protein TerC family
HNQ25_RS13720	COG2259	Doxx family
HNQ25_RS13725	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HNQ25_RS13760	COG0714	Associated with various cellular activities
HNQ25_RS13765	COG0840	transmembrane signaling receptor activity
HNQ25_RS13770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HNQ25_RS13785	COG0628	permease
HNQ25_RS13805	COG1280	lysine exporter protein (LysE YggA)
HNQ25_RS13820	COG1022	Amp-dependent synthetase and ligase
HNQ25_RS13825	COG2062	phosphohistidine phosphatase, SixA
HNQ25_RS13835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HNQ25_RS13840	COG0784	Response regulator, receiver
HNQ25_RS13840	COG5002	protein histidine kinase activity
HNQ25_RS13845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HNQ25_RS13875	COG1368	sulfuric ester hydrolase activity
HNQ25_RS13915	COG0840	transmembrane signaling receptor activity
HNQ25_RS13925	COG1741	Belongs to the pirin family
HNQ25_RS13960	COG2198	Histidine kinase
HNQ25_RS13960	COG2205	protein histidine kinase activity
HNQ25_RS13960	COG0784	Response regulator, receiver
HNQ25_RS13965	COG0326	Molecular chaperone. Has ATPase activity
HNQ25_RS14005	COG0215	cysteine-tRNA ligase activity
HNQ25_RS14010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNQ25_RS14015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNQ25_RS14020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HNQ25_RS14030	COG0589	response to stress
HNQ25_RS14055	COG2197	response regulator
HNQ25_RS14065	COG0436	Aminotransferase
HNQ25_RS14085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HNQ25_RS14085	COG0519	Catalyzes the synthesis of GMP from XMP
HNQ25_RS14100	COG1024	Enoyl-CoA hydratase
HNQ25_RS14100	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNQ25_RS14105	COG0183	Belongs to the thiolase family
HNQ25_RS14125	COG1305	Transglutaminase-like
HNQ25_RS14135	COG2308	Evidence 4 Homologs of previously reported genes of
HNQ25_RS14145	COG3278	Belongs to the heme-copper respiratory oxidase family
HNQ25_RS14160	COG2010	Cytochrome c
HNQ25_RS14165	COG3278	Belongs to the heme-copper respiratory oxidase family
HNQ25_RS14180	COG2010	Cytochrome c
HNQ25_RS14220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HNQ25_RS14225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNQ25_RS14265	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS14270	COG1309	transcriptional regulator
HNQ25_RS14275	COG3132	Protein of unknown function, DUF480
HNQ25_RS14285	COG1846	Transcriptional regulator
HNQ25_RS14290	COG1764	response to oxidative stress
HNQ25_RS14310	COG0174	glutamine synthetase
HNQ25_RS14320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS14330	COG2207	Transcriptional regulator
HNQ25_RS14335	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS14345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNQ25_RS14350	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNQ25_RS14355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNQ25_RS14375	COG0328	RNA-DNA hybrid ribonuclease activity
HNQ25_RS14400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HNQ25_RS14415	COG0328	RNA-DNA hybrid ribonuclease activity
HNQ25_RS14420	COG3617	BRO family, N-terminal domain
HNQ25_RS14485	COG3224	Antibiotic biosynthesis monooxygenase
HNQ25_RS14490	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HNQ25_RS14495	COG0477	Major facilitator Superfamily
HNQ25_RS14510	COG2197	response regulator
HNQ25_RS14520	COG0625	glutathione transferase activity
HNQ25_RS14525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS14535	COG1595	DNA-templated transcription, initiation
HNQ25_RS14540	COG3712	iron ion homeostasis
HNQ25_RS14545	COG4774	siderophore transport
HNQ25_RS14560	COG3135	benzoate transporter
HNQ25_RS14575	COG0284	orotidine-5'-phosphate decarboxylase activity
HNQ25_RS14580	COG4303	Ethanolamine ammonia lyase large subunit
HNQ25_RS14585	COG4302	ethanolamine ammonia-lyase activity
HNQ25_RS14610	COG1309	transcriptional regulator
HNQ25_RS14625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HNQ25_RS14630	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS14635	COG1024	Enoyl-CoA hydratase
HNQ25_RS14650	COG0318	PFAM AMP-dependent synthetase and ligase
HNQ25_RS14670	COG2304	oxidoreductase activity
HNQ25_RS14675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS14730	COG1286	toxin biosynthetic process
HNQ25_RS14740	COG0285	dihydrofolate synthase activity
HNQ25_RS14745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HNQ25_RS14750	COG0135	phosphoribosylanthranilate isomerase activity
HNQ25_RS14775	COG0473	3-isopropylmalate dehydrogenase activity
HNQ25_RS14780	COG0066	3-isopropylmalate dehydratase activity
HNQ25_RS14785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNQ25_RS14865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNQ25_RS14870	COG0583	DNA-binding transcription factor activity
HNQ25_RS14885	COG0556	nucleotide-excision repair
HNQ25_RS14900	COG1555	photosystem II stabilization
HNQ25_RS14915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNQ25_RS14930	COG1086	Polysaccharide biosynthesis protein
HNQ25_RS14965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNQ25_RS14970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNQ25_RS14990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HNQ25_RS14995	COG0776	regulation of translation
HNQ25_RS15005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HNQ25_RS15010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HNQ25_RS15025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HNQ25_RS15035	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HNQ25_RS15040	COG0402	S-adenosylhomocysteine deaminase activity
HNQ25_RS15045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HNQ25_RS15055	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS15075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNQ25_RS15080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNQ25_RS15085	COG0180	Tryptophanyl-tRNA synthetase
HNQ25_RS15090	COG0009	L-threonylcarbamoyladenylate synthase
HNQ25_RS15095	COG0613	PHP domain protein
HNQ25_RS15100	COG2350	Protein conserved in bacteria
HNQ25_RS15110	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS15130	COG0727	PFAM Uncharacterised protein family (UPF0153)
HNQ25_RS15135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HNQ25_RS15140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HNQ25_RS15165	COG0297	glycogen (starch) synthase activity
HNQ25_RS15175	COG2207	Transcriptional regulator
HNQ25_RS15180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNQ25_RS15195	COG1752	Esterase of the alpha-beta hydrolase superfamily
HNQ25_RS15210	COG5001	Diguanylate cyclase
HNQ25_RS15210	COG4251	negative regulation of phosphorylation
HNQ25_RS15210	COG3706	GGDEF domain
HNQ25_RS15210	COG2203	Gaf domain
HNQ25_RS15215	COG0514	ATP-dependent DNA helicase (RecQ)
HNQ25_RS15225	COG2832	Protein of unknown function (DUF454)
HNQ25_RS15235	COG2200	EAL domain
HNQ25_RS15235	COG2199	diguanylate cyclase activity
HNQ25_RS15255	COG2274	protein secretion by the type I secretion system
HNQ25_RS15260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS15270	COG0840	transmembrane signaling receptor activity
HNQ25_RS15290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNQ25_RS15295	COG1126	abc transporter atp-binding protein
HNQ25_RS15310	COG3314	Sporulation integral membrane protein YlbJ
HNQ25_RS15320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HNQ25_RS15325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HNQ25_RS15330	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HNQ25_RS15340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HNQ25_RS15385	COG0542	response to heat
HNQ25_RS15410	COG0121	glutamine amidotransferase
HNQ25_RS15425	COG1770	oligopeptidase
HNQ25_RS15450	COG2983	Belongs to the UPF0260 family
HNQ25_RS15455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNQ25_RS15460	COG3100	YcgL domain-containing protein
HNQ25_RS15480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HNQ25_RS15500	COG2197	response regulator
HNQ25_RS15515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HNQ25_RS15535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HNQ25_RS15545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HNQ25_RS15555	COG1492	cobalamin metabolic process
HNQ25_RS15565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HNQ25_RS15570	COG0778	Nitroreductase
HNQ25_RS15575	COG1797	cobyrinic acid a,c-diamide synthase activity
HNQ25_RS15590	COG0791	NLP P60 protein
HNQ25_RS15590	COG0741	lytic transglycosylase activity
HNQ25_RS15595	COG0791	NLP P60 protein
HNQ25_RS15605	COG0521	Mo-molybdopterin cofactor biosynthetic process
HNQ25_RS15610	COG0746	molybdenum cofactor guanylyltransferase activity
HNQ25_RS15640	COG4568	rho-dependent transcription termination
HNQ25_RS15650	COG3956	TIGRFAM MazG family protein
HNQ25_RS15655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNQ25_RS15660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNQ25_RS15680	COG0784	Response regulator, receiver
HNQ25_RS15680	COG5002	protein histidine kinase activity
HNQ25_RS15680	COG2205	protein histidine kinase activity
HNQ25_RS15685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNQ25_RS15700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNQ25_RS15720	COG3038	cytochrome b561
HNQ25_RS15725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HNQ25_RS15755	COG0840	transmembrane signaling receptor activity
HNQ25_RS15760	COG0733	neurotransmitter:sodium symporter activity
HNQ25_RS15765	COG0625	glutathione transferase activity
HNQ25_RS15775	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HNQ25_RS15785	COG2329	Antibiotic biosynthesis monooxygenase
HNQ25_RS15790	COG0504	CTP synthase activity
HNQ25_RS15795	COG0583	DNA-binding transcription factor activity
HNQ25_RS15810	COG1054	Belongs to the UPF0176 family
HNQ25_RS15815	COG0271	Belongs to the BolA IbaG family
HNQ25_RS15830	COG0114	fumarate hydratase activity
HNQ25_RS15835	COG2249	NAD(P)H dehydrogenase (quinone) activity
HNQ25_RS15845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HNQ25_RS15850	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HNQ25_RS15855	COG3454	Phosphonate metabolism
HNQ25_RS15860	COG4778	phosphonate C-P lyase system protein PhnL
HNQ25_RS15865	COG4107	phosphonate C-P lyase system protein PhnK
HNQ25_RS15870	COG3627	carbon phosphorus lyase activity
HNQ25_RS15875	COG3626	phosphonate metabolism
HNQ25_RS15885	COG3624	Phosphonate C-P lyase system protein PhnG
HNQ25_RS15890	COG2188	Transcriptional regulator
HNQ25_RS15895	COG3639	organic phosphonate transmembrane transporter activity
HNQ25_RS15900	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HNQ25_RS15905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HNQ25_RS15920	COG0511	ligase activity, forming carbon-carbon bonds
HNQ25_RS15920	COG5016	pyruvate
HNQ25_RS15925	COG3630	sodium ion export across plasma membrane
HNQ25_RS15930	COG2207	Transcriptional regulator
HNQ25_RS15935	COG4221	oxidoreductase activity
HNQ25_RS15950	COG2239	Acts as a magnesium transporter
HNQ25_RS15980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HNQ25_RS15985	COG0527	aspartate kinase activity
HNQ25_RS15990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNQ25_RS15995	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HNQ25_RS16000	COG2988	succinylglutamate desuccinylase activity
HNQ25_RS16010	COG3724	N-succinylarginine dihydrolase activity
HNQ25_RS16015	COG1012	belongs to the aldehyde dehydrogenase family
HNQ25_RS16030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HNQ25_RS16050	COG4215	(ABC) transporter
HNQ25_RS16115	COG0154	amidase activity
HNQ25_RS16165	COG0693	protein deglycase activity
HNQ25_RS16170	COG2199	diguanylate cyclase activity
HNQ25_RS16230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HNQ25_RS16230	COG0473	3-isopropylmalate dehydrogenase activity
HNQ25_RS16240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HNQ25_RS16250	COG1104	cysteine desulfurase activity
HNQ25_RS16255	COG0084	hydrolase, TatD family'
HNQ25_RS16270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNQ25_RS16275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNQ25_RS16285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HNQ25_RS16290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNQ25_RS16305	COG0416	fatty acid biosynthetic process
HNQ25_RS16310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HNQ25_RS16315	COG1399	metal-binding, possibly nucleic acid-binding protein
HNQ25_RS16320	COG0424	maF-like protein
HNQ25_RS16325	COG0616	signal peptide processing
HNQ25_RS16325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HNQ25_RS16330	COG0546	phosphoglycolate phosphatase activity
HNQ25_RS16340	COG1530	ribonuclease E activity
HNQ25_RS16345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HNQ25_RS16350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNQ25_RS16355	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HNQ25_RS16360	COG2835	tetraacyldisaccharide 4'-kinase activity
HNQ25_RS16365	COG1663	tetraacyldisaccharide 4'-kinase activity
HNQ25_RS16370	COG0848	biopolymer transport protein
HNQ25_RS16375	COG0811	peptide transport
HNQ25_RS16390	COG4591	ABC-type transport system involved in lipoprotein release permease component
HNQ25_RS16395	COG1136	(ABC) transporter
HNQ25_RS16400	COG4591	ABC-type transport system involved in lipoprotein release permease component
HNQ25_RS16415	COG0584	glycerophosphoryl diester phosphodiesterase
HNQ25_RS16420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNQ25_RS16430	COG1477	protein flavinylation
HNQ25_RS16455	COG1805	sodium ion transport
HNQ25_RS16470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNQ25_RS16480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HNQ25_RS16500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HNQ25_RS16530	COG0183	Belongs to the thiolase family
HNQ25_RS16535	COG1024	Enoyl-CoA hydratase
HNQ25_RS16535	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNQ25_RS16545	COG0589	response to stress
HNQ25_RS16555	COG0488	(ABC) transporter
HNQ25_RS16560	COG0741	lytic transglycosylase activity
HNQ25_RS16585	COG1070	Carbohydrate kinase
HNQ25_RS16595	COG0277	FAD linked oxidase domain protein
HNQ25_RS16595	COG0277	FAD linked oxidase domain protein
HNQ25_RS16640	COG1595	DNA-templated transcription, initiation
HNQ25_RS16650	COG0069	glutamate synthase activity
HNQ25_RS16670	COG0583	DNA-binding transcription factor activity
HNQ25_RS16675	COG1056	cytidyltransferase-related domain
HNQ25_RS16675	COG3172	ATPase kinase involved in NAD metabolism
HNQ25_RS16705	COG0537	adenosine 5'-monophosphoramidase activity
HNQ25_RS16710	COG0625	glutathione transferase activity
HNQ25_RS16725	COG0583	DNA-binding transcription factor activity
HNQ25_RS16730	COG2814	Major facilitator Superfamily
HNQ25_RS16755	COG2188	Transcriptional regulator
HNQ25_RS16760	COG2851	Citrate transporter
HNQ25_RS16780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS16800	COG0840	transmembrane signaling receptor activity
HNQ25_RS16810	COG0640	Transcriptional regulator
HNQ25_RS16820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNQ25_RS16825	COG0431	NADPH-dependent FMN reductase
HNQ25_RS16845	COG1845	cytochrome c oxidase, subunit III
HNQ25_RS16855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HNQ25_RS16870	COG1643	Atp-dependent helicase
HNQ25_RS16900	COG2814	Major facilitator Superfamily
HNQ25_RS16905	COG0583	DNA-binding transcription factor activity
HNQ25_RS16910	COG1846	Transcriptional regulator
HNQ25_RS16920	COG2807	transmembrane transport
HNQ25_RS16925	COG0318	PFAM AMP-dependent synthetase and ligase
HNQ25_RS16930	COG0318	PFAM AMP-dependent synthetase and ligase
HNQ25_RS16940	COG2030	dehydratase
HNQ25_RS16950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HNQ25_RS16955	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNQ25_RS16955	COG2508	Transcriptional regulator
HNQ25_RS16960	COG0402	S-adenosylhomocysteine deaminase activity
HNQ25_RS16965	COG1566	PFAM secretion protein HlyD family protein
HNQ25_RS16975	COG1289	transmembrane transporter activity
HNQ25_RS17000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HNQ25_RS17005	COG4941	Belongs to the sigma-70 factor family
HNQ25_RS17015	COG4106	trans-aconitate 2-methyltransferase activity
HNQ25_RS17020	COG0500	methyltransferase
HNQ25_RS17030	COG0583	DNA-binding transcription factor activity
HNQ25_RS17035	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HNQ25_RS17045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNQ25_RS17050	COG0571	ribonuclease III activity
HNQ25_RS17065	COG0481	GTPase activity
HNQ25_RS17070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNQ25_RS17125	COG0642	Histidine kinase
HNQ25_RS17155	COG3180	Ammonia monooxygenase
HNQ25_RS17160	COG0583	DNA-binding transcription factor activity
HNQ25_RS17165	COG3976	FMN-binding domain protein
HNQ25_RS17165	COG1053	succinate dehydrogenase
HNQ25_RS17165	COG0431	NADPH-dependent FMN reductase
HNQ25_RS17180	COG0564	pseudouridine synthase activity
HNQ25_RS17210	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HNQ25_RS17220	COG1320	monovalent cation:proton antiporter activity
HNQ25_RS17225	COG2212	antiporter activity
HNQ25_RS17230	COG1863	multisubunit Na H antiporter MnhE subunit
HNQ25_RS17235	COG0651	ATP synthesis coupled electron transport
HNQ25_RS17240	COG1006	Multisubunit Na H antiporter MnhC subunit
HNQ25_RS17245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HNQ25_RS17245	COG2111	Na H antiporter
HNQ25_RS17255	COG1929	Belongs to the glycerate kinase type-1 family
HNQ25_RS17260	COG2610	gluconate transmembrane transporter activity
HNQ25_RS17265	COG3835	regulator
HNQ25_RS17270	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HNQ25_RS17275	COG0259	pyridoxamine-phosphate oxidase activity
HNQ25_RS17290	COG2111	Na H antiporter
HNQ25_RS17290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HNQ25_RS17295	COG1006	Multisubunit Na H antiporter MnhC subunit
HNQ25_RS17300	COG0651	ATP synthesis coupled electron transport
HNQ25_RS17305	COG1863	multisubunit Na H antiporter MnhE subunit
HNQ25_RS17310	COG2212	antiporter activity
HNQ25_RS17315	COG1320	monovalent cation:proton antiporter activity
HNQ25_RS17320	COG1199	ATP-dependent helicase activity
HNQ25_RS17350	COG3012	SEC-C Motif Domain Protein
HNQ25_RS17370	COG0653	protein targeting
HNQ25_RS17390	COG1335	isochorismatase
HNQ25_RS17395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNQ25_RS17400	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HNQ25_RS17415	COG0717	Belongs to the dCTP deaminase family
HNQ25_RS17420	COG1278	Cold shock
HNQ25_RS17425	COG0489	protein tyrosine kinase activity
HNQ25_RS17430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNQ25_RS17430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNQ25_RS17440	COG4657	Part of a membrane complex involved in electron transport
HNQ25_RS17445	COG2878	Part of a membrane complex involved in electron transport
HNQ25_RS17455	COG4658	electron transport chain
HNQ25_RS17460	COG4659	FMN binding
HNQ25_RS17470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNQ25_RS17480	COG0346	lactoylglutathione lyase activity
HNQ25_RS17485	COG0137	argininosuccinate synthase activity
HNQ25_RS17495	COG0418	dihydroorotase activity
HNQ25_RS17550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNQ25_RS17575	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS17580	COG1024	Enoyl-CoA hydratase
HNQ25_RS17585	COG1024	Enoyl-CoA hydratase
HNQ25_RS17585	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNQ25_RS17595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS17620	COG3300	MHYT domain
HNQ25_RS17620	COG5001	Diguanylate cyclase
HNQ25_RS17660	COG3842	ATPase activity
HNQ25_RS17680	COG3665	Urea carboxylase-associated protein
HNQ25_RS17685	COG3665	Urea carboxylase-associated protein
HNQ25_RS17690	COG0439	Biotin carboxylase
HNQ25_RS17720	COG4974	Belongs to the 'phage' integrase family
HNQ25_RS17775	COG0668	transmembrane transport
HNQ25_RS17805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HNQ25_RS17805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HNQ25_RS17815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HNQ25_RS17820	COG0431	NADPH-dependent FMN reductase
HNQ25_RS17840	COG2866	Carboxypeptidase
HNQ25_RS17860	COG3795	YCII-related domain
HNQ25_RS17890	COG3842	ATPase activity
HNQ25_RS17900	COG0583	DNA-binding transcription factor activity
HNQ25_RS17905	COG3257	ureidoglycine aminohydrolase activity
HNQ25_RS17950	COG3339	Conserved Protein
HNQ25_RS17955	COG0545	Peptidyl-prolyl cis-trans isomerase
HNQ25_RS17970	COG2974	May be involved in recombination
HNQ25_RS17985	COG1803	Methylglyoxal synthase
HNQ25_RS18000	COG1132	(ABC) transporter
HNQ25_RS18005	COG0513	Belongs to the DEAD box helicase family
HNQ25_RS18030	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNQ25_RS18045	COG0596	Alpha beta hydrolase
HNQ25_RS18060	COG0583	DNA-binding transcription factor activity
HNQ25_RS18075	COG0697	spore germination
HNQ25_RS18080	COG3148	PFAM DTW domain containing protein
HNQ25_RS18100	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HNQ25_RS18110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HNQ25_RS18120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HNQ25_RS18125	COG0602	queuosine metabolic process
HNQ25_RS18130	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HNQ25_RS18135	COG2885	chlorophyll binding
HNQ25_RS18160	COG0824	Thioesterase
HNQ25_RS18165	COG2255	four-way junction helicase activity
HNQ25_RS18170	COG0632	four-way junction helicase activity
HNQ25_RS18175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HNQ25_RS18185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HNQ25_RS18190	COG0783	Belongs to the Dps family
HNQ25_RS18195	COG3706	GGDEF domain
HNQ25_RS18205	COG2900	Belongs to the SlyX family
HNQ25_RS18225	COG0442	prolyl-tRNA aminoacylation
HNQ25_RS18235	COG0656	L-ascorbic acid biosynthetic process
HNQ25_RS18260	COG4628	conserved protein (DUF2132)
HNQ25_RS18265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HNQ25_RS18275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HNQ25_RS18290	COG1742	UPF0060 membrane protein
HNQ25_RS18330	COG2853	Lipoprotein
HNQ25_RS18345	COG1560	Kdo2-lipid A biosynthetic process
HNQ25_RS18350	COG0850	regulation of cytokinetic process
HNQ25_RS18355	COG2894	cell division
HNQ25_RS18360	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HNQ25_RS18365	COG0564	pseudouridine synthase activity
HNQ25_RS18370	COG1362	aminopeptidase activity
HNQ25_RS18375	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HNQ25_RS18390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HNQ25_RS18400	COG0842	Transport permease protein
HNQ25_RS18405	COG1131	(ABC) transporter
HNQ25_RS18410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNQ25_RS18415	COG0277	FAD linked oxidase domain protein
HNQ25_RS18420	COG2721	sulfolactate sulfo-lyase activity
HNQ25_RS18425	COG2271	Major facilitator Superfamily
HNQ25_RS18435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNQ25_RS18440	COG4948	Mandelate Racemase Muconate Lactonizing
HNQ25_RS18445	COG3181	Tripartite tricarboxylate transporter family receptor
HNQ25_RS18465	COG0583	DNA-binding transcription factor activity
HNQ25_RS18485	COG0545	Peptidyl-prolyl cis-trans isomerase
HNQ25_RS18490	COG2202	Pas domain
HNQ25_RS18490	COG2205	protein histidine kinase activity
HNQ25_RS18510	COG3046	protein related to deoxyribodipyrimidine photolyase
HNQ25_RS18525	COG2862	Uncharacterized protein family, UPF0114
HNQ25_RS18535	COG1067	ATP-dependent peptidase activity
HNQ25_RS18565	COG4974	Belongs to the 'phage' integrase family
HNQ25_RS18625	COG4974	Belongs to the 'phage' integrase family
HNQ25_RS18650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNQ25_RS18675	COG2828	Protein conserved in bacteria
HNQ25_RS18680	COG0583	DNA-binding transcription factor activity
HNQ25_RS18685	COG1944	ATP diphosphatase activity
HNQ25_RS18695	COG0583	DNA-binding transcription factor activity
HNQ25_RS18700	COG1301	dicarboxylic acid transport
HNQ25_RS18710	COG0165	Argininosuccinate lyase
HNQ25_RS18730	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
HNQ25_RS18740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNQ25_RS18750	COG3665	Urea carboxylase-associated protein
HNQ25_RS18760	COG0765	amino acid transport
HNQ25_RS18770	COG0583	DNA-binding transcription factor activity
HNQ25_RS18775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HNQ25_RS18780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HNQ25_RS18790	COG2031	fatty acid transporter
HNQ25_RS18815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNQ25_RS18865	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
HNQ25_RS18870	COG0640	Transcriptional regulator
HNQ25_RS18875	COG1902	pentaerythritol trinitrate reductase activity
HNQ25_RS18890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HNQ25_RS18895	COG0583	DNA-binding transcription factor activity
HNQ25_RS18910	COG0583	DNA-binding transcription factor activity
HNQ25_RS18930	COG0583	DNA-binding transcription factor activity
HNQ25_RS18935	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HNQ25_RS18935	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HNQ25_RS18935	COG0506	proline dehydrogenase activity
HNQ25_RS18945	COG2235	arginine
HNQ25_RS18965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNQ25_RS18970	COG2814	Major facilitator Superfamily
HNQ25_RS18985	COG4221	oxidoreductase activity
HNQ25_RS19005	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HNQ25_RS19010	COG2824	Alkylphosphonate utilization operon protein PhnA
HNQ25_RS19025	COG2271	Major facilitator Superfamily
HNQ25_RS19030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HNQ25_RS19035	COG1090	epimerase
HNQ25_RS19040	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HNQ25_RS19055	COG0789	Transcriptional regulator
HNQ25_RS19070	COG4221	oxidoreductase activity
HNQ25_RS19085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HNQ25_RS19105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HNQ25_RS19110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HNQ25_RS19120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNQ25_RS19125	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HNQ25_RS19135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HNQ25_RS19140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HNQ25_RS19155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNQ25_RS19160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HNQ25_RS19165	COG0193	aminoacyl-tRNA hydrolase activity
HNQ25_RS19240	COG0697	spore germination
HNQ25_RS19260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HNQ25_RS19265	COG0315	cyclic pyranopterin monophosphate synthase activity
HNQ25_RS19270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HNQ25_RS19275	COG3022	response to hydroperoxide
HNQ25_RS19305	COG3420	alginic acid biosynthetic process
HNQ25_RS19345	COG0300	oxidoreductase activity
HNQ25_RS19360	COG0492	ferredoxin-NADP+ reductase activity
HNQ25_RS19365	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HNQ25_RS19425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HNQ25_RS19465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HNQ25_RS19470	COG1047	Peptidyl-prolyl cis-trans
HNQ25_RS19475	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNQ25_RS19480	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNQ25_RS19485	COG0196	riboflavin kinase activity
HNQ25_RS19495	COG0268	Binds directly to 16S ribosomal RNA
HNQ25_RS19505	COG0659	secondary active sulfate transmembrane transporter activity
HNQ25_RS19510	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HNQ25_RS19515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNQ25_RS19535	COG3695	enzyme binding
HNQ25_RS19545	COG0668	transmembrane transport
HNQ25_RS19550	COG1666	GTP binding
HNQ25_RS19555	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS19570	COG2096	Adenosyltransferase
HNQ25_RS19580	COG0494	nUDIX hydrolase
HNQ25_RS19590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HNQ25_RS19595	COG0653	protein targeting
HNQ25_RS19610	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HNQ25_RS19630	COG1181	Belongs to the D-alanine--D-alanine ligase family
HNQ25_RS19635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HNQ25_RS19640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNQ25_RS19645	COG0772	Belongs to the SEDS family
HNQ25_RS19650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNQ25_RS19655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNQ25_RS19660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HNQ25_RS19665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNQ25_RS19680	COG0275	rRNA processing
HNQ25_RS19685	COG2001	Belongs to the MraZ family
HNQ25_RS19700	COG3107	peptidoglycan biosynthetic process
HNQ25_RS19705	COG0792	nuclease activity
HNQ25_RS19710	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HNQ25_RS19715	COG2823	Periplasmic or secreted lipoprotein
HNQ25_RS19720	COG2969	positive regulation of protein catabolic process
HNQ25_RS19725	COG0625	glutathione transferase activity
HNQ25_RS19730	COG2857	Cytochrome c1
HNQ25_RS19735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HNQ25_RS19740	COG0723	plastoquinol--plastocyanin reductase activity
HNQ25_RS19745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HNQ25_RS19750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNQ25_RS19755	COG0667	Aldo Keto reductase
HNQ25_RS19760	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS19775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HNQ25_RS19810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HNQ25_RS19825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HNQ25_RS19835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HNQ25_RS19840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNQ25_RS19860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HNQ25_RS19865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HNQ25_RS19870	COG1127	ABC transporter
HNQ25_RS19880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HNQ25_RS19890	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HNQ25_RS19895	COG1137	ATPase activity
HNQ25_RS19900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HNQ25_RS19915	COG1660	Displays ATPase and GTPase activities
HNQ25_RS19920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNQ25_RS19925	COG0312	modulator of DNA gyrase
HNQ25_RS19930	COG3028	Belongs to the UPF0307 family
HNQ25_RS19935	COG0312	modulator of DNA gyrase
HNQ25_RS19940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNQ25_RS19950	COG1530	ribonuclease E activity
HNQ25_RS19955	COG0424	maF-like protein
HNQ25_RS19965	COG1792	Involved in formation and maintenance of cell shape
HNQ25_RS19970	COG1077	Cell shape determining protein MreB Mrl
HNQ25_RS19975	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNQ25_RS19980	COG0154	amidase activity
HNQ25_RS19985	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNQ25_RS19990	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNQ25_RS20000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNQ25_RS20010	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HNQ25_RS20015	COG3852	Histidine kinase
HNQ25_RS20025	COG0747	negative chemotaxis
HNQ25_RS20030	COG0747	negative chemotaxis
HNQ25_RS20035	COG0006	proline dipeptidase activity
HNQ25_RS20045	COG0747	negative chemotaxis
HNQ25_RS20050	COG0601	transmembrane transport
HNQ25_RS20055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HNQ25_RS20060	COG0444	Belongs to the ABC transporter superfamily
HNQ25_RS20065	COG4608	Belongs to the ABC transporter superfamily
HNQ25_RS20075	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HNQ25_RS20075	COG2169	Transcriptional regulator
HNQ25_RS20080	COG0693	protein deglycase activity
HNQ25_RS20085	COG2252	PERMEase
HNQ25_RS20090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNQ25_RS20105	COG2321	neutral zinc metallopeptidase
HNQ25_RS20110	COG2814	Major facilitator Superfamily
HNQ25_RS20125	COG1309	transcriptional regulator
HNQ25_RS20140	COG2217	Heavy metal translocating P-type atpase
HNQ25_RS20155	COG0583	DNA-binding transcription factor activity
HNQ25_RS20160	COG2910	NAD(P)H-binding
HNQ25_RS20175	COG4771	TonB-dependent receptor
HNQ25_RS20185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HNQ25_RS20190	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNQ25_RS20195	COG4993	Dehydrogenase
HNQ25_RS20205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HNQ25_RS20220	COG0410	ABC transporter
HNQ25_RS20225	COG1129	ABC transporter
HNQ25_RS20245	COG2198	Histidine kinase
HNQ25_RS20245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HNQ25_RS20245	COG2205	protein histidine kinase activity
HNQ25_RS20245	COG0784	Response regulator, receiver
HNQ25_RS20265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNQ25_RS20265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HNQ25_RS20265	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HNQ25_RS20270	COG1105	Belongs to the carbohydrate kinase PfkB family
HNQ25_RS20275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNQ25_RS20275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HNQ25_RS20285	COG2982	Protein involved in outer membrane biogenesis
HNQ25_RS20290	COG0084	hydrolase, TatD family'
HNQ25_RS20305	COG3023	N-Acetylmuramoyl-L-alanine amidase
HNQ25_RS20345	COG0237	dephospho-CoA kinase activity
HNQ25_RS20355	COG2801	Transposase and inactivated derivatives
HNQ25_RS20355	COG3415	Transposase
HNQ25_RS20375	COG1799	cell septum assembly
HNQ25_RS20385	COG1252	NADH dehydrogenase
HNQ25_RS20390	COG3158	transport of potassium into the cell
HNQ25_RS20420	COG0488	(ABC) transporter
HNQ25_RS20470	COG1253	flavin adenine dinucleotide binding
HNQ25_RS20480	COG2813	Specifically methylates the guanine in position
HNQ25_RS20500	COG0312	modulator of DNA gyrase
HNQ25_RS20510	COG1294	oxidase, subunit
HNQ25_RS20515	COG1271	oxidase subunit
HNQ25_RS20545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HNQ25_RS20585	COG0840	transmembrane signaling receptor activity
HNQ25_RS20590	COG4953	penicillin-binding protein 1C
HNQ25_RS20595	COG2852	Protein conserved in bacteria
HNQ25_RS20600	COG2373	Large extracellular alpha-helical protein
HNQ25_RS20605	COG0534	Mate efflux family protein
HNQ25_RS20620	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HNQ25_RS20625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HNQ25_RS20640	COG1166	arginine decarboxylase activity
HNQ25_RS20645	COG0023	Translation Initiation Factor
HNQ25_RS20680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS20700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HNQ25_RS20715	COG2264	protein methyltransferase activity
HNQ25_RS20735	COG0138	bifunctional purine biosynthesis protein purh
HNQ25_RS20750	COG2095	MarC family integral membrane protein
HNQ25_RS20765	COG1802	Transcriptional regulator
HNQ25_RS20785	COG0411	ABC transporter
HNQ25_RS20795	COG0235	Class ii aldolase
HNQ25_RS20800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HNQ25_RS20805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HNQ25_RS20810	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HNQ25_RS20815	COG0765	amino acid transport
HNQ25_RS20820	COG4215	(ABC) transporter
HNQ25_RS20830	COG4221	oxidoreductase activity
HNQ25_RS20840	COG0829	nickel cation binding
HNQ25_RS20845	COG0831	urea catabolic process
HNQ25_RS20860	COG0832	Belongs to the urease beta subunit family
HNQ25_RS20865	COG0804	urea catabolic process
HNQ25_RS20870	COG1943	Transposase
HNQ25_RS20880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HNQ25_RS20885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HNQ25_RS20915	COG1238	metal cluster binding
HNQ25_RS20925	COG0443	Heat shock 70 kDa protein
HNQ25_RS20950	COG0174	glutamine synthetase
HNQ25_RS20955	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS20965	COG0583	DNA-binding transcription factor activity
HNQ25_RS20970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HNQ25_RS20985	COG2267	carboxylic ester hydrolase activity
HNQ25_RS21010	COG1309	transcriptional regulator
HNQ25_RS21015	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HNQ25_RS21020	COG0830	nickel cation binding
HNQ25_RS21025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HNQ25_RS21035	COG0584	glycerophosphoryl diester phosphodiesterase
HNQ25_RS21050	COG2354	Protein conserved in bacteria
HNQ25_RS21060	COG2308	Evidence 4 Homologs of previously reported genes of
HNQ25_RS21080	COG4106	trans-aconitate 2-methyltransferase activity
HNQ25_RS21085	COG1032	radical SAM domain protein
HNQ25_RS21090	COG5001	Diguanylate cyclase
HNQ25_RS21090	COG3300	MHYT domain
HNQ25_RS21100	COG0305	Participates in initiation and elongation during chromosome replication
HNQ25_RS21105	COG0359	binds to the 23S rRNA
HNQ25_RS21115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNQ25_RS21120	COG0360	Binds together with S18 to 16S ribosomal RNA
HNQ25_RS21125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNQ25_RS21130	COG0557	exoribonuclease II activity
HNQ25_RS21145	COG0840	transmembrane signaling receptor activity
HNQ25_RS21150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNQ25_RS21155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HNQ25_RS21165	COG0330	HflC and HflK could
HNQ25_RS21170	COG0330	HflC and HflK could
HNQ25_RS21175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNQ25_RS21180	COG1923	regulation of RNA biosynthetic process
HNQ25_RS21185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNQ25_RS21190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNQ25_RS21195	COG0860	N-Acetylmuramoyl-L-alanine amidase
HNQ25_RS21200	COG0802	atpase or kinase
HNQ25_RS21205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HNQ25_RS21205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNQ25_RS21215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HNQ25_RS21225	COG1162	GTPase activity
HNQ25_RS21235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HNQ25_RS21250	COG0688	phosphatidylethanolamine metabolic process
HNQ25_RS21265	COG0560	Phosphoserine phosphatase
HNQ25_RS21265	COG3830	Belongs to the UPF0237 family
HNQ25_RS21280	COG0667	Aldo Keto reductase
HNQ25_RS21300	COG1519	Transferase
HNQ25_RS21305	COG1538	Outer membrane efflux protein
HNQ25_RS21310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HNQ25_RS21315	COG0494	nUDIX hydrolase
HNQ25_RS21325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HNQ25_RS21330	COG3150	esterase
HNQ25_RS21360	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS21370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HNQ25_RS21370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HNQ25_RS21385	COG1132	(ABC) transporter
HNQ25_RS21405	COG1215	transferase activity, transferring glycosyl groups
HNQ25_RS21420	COG0438	transferase activity, transferring glycosyl groups
HNQ25_RS21425	COG2192	nodulation
HNQ25_RS21450	COG0438	transferase activity, transferring glycosyl groups
HNQ25_RS21495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNQ25_RS21510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HNQ25_RS21520	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS21525	COG3263	regulation of cellular component size
HNQ25_RS21530	COG1196	nuclear chromosome segregation
HNQ25_RS21530	COG3264	Mechanosensitive ion channel
HNQ25_RS21535	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HNQ25_RS21540	COG3273	potassium ion transport
HNQ25_RS21540	COG0471	metal ion transport
HNQ25_RS21545	COG3118	belongs to the thioredoxin family
HNQ25_RS21560	COG1192	Involved in chromosome partitioning
HNQ25_RS21580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNQ25_RS21590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HNQ25_RS21605	COG2986	histidine ammonia-lyase
HNQ25_RS21635	COG2226	methyltransferase
HNQ25_RS21655	COG1028	Short-chain dehydrogenase reductase Sdr
HNQ25_RS21685	COG1131	(ABC) transporter
HNQ25_RS21720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNQ25_RS21735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HNQ25_RS21740	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HNQ25_RS21745	COG1116	anion transmembrane transporter activity
HNQ25_RS21750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HNQ25_RS21755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HNQ25_RS21760	COG3604	Transcriptional regulator
HNQ25_RS21765	COG0493	'glutamate synthase
HNQ25_RS21770	COG0070	glutamate synthase
HNQ25_RS21770	COG0069	glutamate synthase activity
HNQ25_RS21770	COG0067	glutamate synthase
HNQ25_RS21780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HNQ25_RS21785	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HNQ25_RS21820	COG0281	malic enzyme
HNQ25_RS21835	COG0254	rRNA binding
HNQ25_RS21840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNQ25_RS21845	COG0018	arginyl-trna synthetase
HNQ25_RS21855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HNQ25_RS21860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HNQ25_RS21885	COG1309	transcriptional regulator
HNQ25_RS21905	COG2226	methyltransferase
HNQ25_RS21915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HNQ25_RS21925	COG0140	phosphoribosyl-ATP diphosphatase activity
HNQ25_RS21930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNQ25_RS21935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNQ25_RS21950	COG1490	D-aminoacyl-tRNA deacylase activity
HNQ25_RS21980	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HNQ25_RS22015	COG3246	L-lysine catabolic process to acetate
HNQ25_RS22040	COG1902	pentaerythritol trinitrate reductase activity
HNQ25_RS22040	COG0446	pyridine nucleotide-disulphide oxidoreductase
HNQ25_RS22045	COG2181	nitrate reductase activity
HNQ25_RS22045	COG0247	lactate metabolic process
HNQ25_RS22050	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HNQ25_RS22075	COG4175	Glycine betaine
HNQ25_RS22080	COG4176	ABC-type proline glycine betaine transport system permease component
HNQ25_RS22095	COG1309	transcriptional regulator
HNQ25_RS22100	COG1012	belongs to the aldehyde dehydrogenase family
HNQ25_RS22105	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HNQ25_RS22110	COG1879	ABC-type sugar transport system periplasmic component
HNQ25_RS22115	COG0477	Major facilitator Superfamily
HNQ25_RS22120	COG0513	Belongs to the DEAD box helicase family
HNQ25_RS22125	COG3706	GGDEF domain
HNQ25_RS22135	COG2081	HI0933 family
HNQ25_RS22140	COG3273	potassium ion transport
HNQ25_RS22140	COG0471	metal ion transport
HNQ25_RS22145	COG0686	Belongs to the AlaDH PNT family
HNQ25_RS22150	COG0625	glutathione transferase activity
HNQ25_RS22165	COG1289	transmembrane transporter activity
HNQ25_RS22175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HNQ25_RS22185	COG1451	nucleotide metabolic process
HNQ25_RS22190	COG2133	pyrroloquinoline quinone binding
HNQ25_RS22215	COG0126	phosphoglycerate kinase activity
HNQ25_RS22220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HNQ25_RS22235	COG0583	DNA-binding transcription factor activity
HNQ25_RS22240	COG2226	methyltransferase
HNQ25_RS22245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNQ25_RS22255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNQ25_RS22280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HNQ25_RS22285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HNQ25_RS22290	COG1611	Belongs to the LOG family
HNQ25_RS22300	COG0513	Belongs to the DEAD box helicase family
HNQ25_RS22305	COG2353	YceI-like domain
HNQ25_RS22310	COG3038	cytochrome b561
HNQ25_RS22320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HNQ25_RS22325	COG1115	amino acid carrier protein
HNQ25_RS22340	COG2198	Histidine kinase
HNQ25_RS22340	COG0784	Response regulator, receiver
HNQ25_RS22340	COG0643	Histidine kinase
HNQ25_RS22370	COG0189	ligase activity
HNQ25_RS22390	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNQ25_RS22395	COG0540	Belongs to the ATCase OTCase family
HNQ25_RS22410	COG1218	3'(2'),5'-bisphosphate nucleotidase
HNQ25_RS22415	COG0494	nUDIX hydrolase
HNQ25_RS22420	COG1011	Hydrolase
HNQ25_RS22425	COG1652	LysM domain
HNQ25_RS22430	COG0583	DNA-binding transcription factor activity
HNQ25_RS22435	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HNQ25_RS22460	COG0824	Thioesterase
HNQ25_RS22465	COG1454	alcohol dehydrogenase
HNQ25_RS22470	COG1960	acyl-CoA dehydrogenase activity
HNQ25_RS22475	COG1250	3-hydroxyacyl-CoA dehydrogenase
HNQ25_RS22475	COG1024	Enoyl-CoA hydratase
HNQ25_RS22490	COG0667	Aldo Keto reductase
HNQ25_RS22505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HNQ25_RS22510	COG1127	ABC transporter
HNQ25_RS22525	COG0514	ATP-dependent DNA helicase (RecQ)
HNQ25_RS22530	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HNQ25_RS22535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNQ25_RS22545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HNQ25_RS22550	COG0189	ligase activity
HNQ25_RS22550	COG4067	protein conserved in archaea
HNQ25_RS22555	COG0189	ligase activity
HNQ25_RS22580	COG2183	response to ionizing radiation
HNQ25_RS22590	COG2918	glutathione biosynthetic process
HNQ25_RS22600	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HNQ25_RS22600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HNQ25_RS22610	COG0306	phosphate transporter
HNQ25_RS22615	COG1392	Phosphate transport regulator
HNQ25_RS22620	COG3025	triphosphatase activity
HNQ25_RS22625	COG1177	transmembrane transport
HNQ25_RS22630	COG1176	ABC-type spermidine putrescine transport system, permease component I
HNQ25_RS22635	COG3842	ATPase activity
HNQ25_RS22660	COG0174	glutamine synthetase
HNQ25_RS22665	COG0174	glutamine synthetase
HNQ25_RS22685	COG2957	Belongs to the agmatine deiminase family
HNQ25_RS22695	COG1858	cytochrome C peroxidase
HNQ25_RS22715	COG0640	Transcriptional regulator
HNQ25_RS22730	COG1178	ABC-type Fe3 transport system permease component
HNQ25_RS22740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HNQ25_RS22745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HNQ25_RS22750	COG0006	proline dipeptidase activity
HNQ25_RS22755	COG3079	Belongs to the UPF0149 family
HNQ25_RS22775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNQ25_RS22785	COG5001	Diguanylate cyclase
HNQ25_RS22785	COG2203	Gaf domain
HNQ25_RS22785	COG4251	negative regulation of phosphorylation
HNQ25_RS22785	COG3706	GGDEF domain
HNQ25_RS22790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNQ25_RS22795	COG1129	ABC transporter
HNQ25_RS22795	COG0842	Transport permease protein
HNQ25_RS22800	COG0842	Transport permease protein
HNQ25_RS22805	COG1580	Controls the rotational direction of flagella during chemotaxis
HNQ25_RS22825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HNQ25_RS22840	COG2186	Transcriptional regulator
HNQ25_RS22845	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HNQ25_RS22850	COG0765	amino acid transport
HNQ25_RS22855	COG0765	amino acid transport
HNQ25_RS22860	COG1126	abc transporter atp-binding protein
HNQ25_RS22870	COG0248	Ppx GppA phosphatase
HNQ25_RS22875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HNQ25_RS22895	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HNQ25_RS22900	COG2050	protein possibly involved in aromatic compounds catabolism
HNQ25_RS22905	COG1671	Belongs to the UPF0178 family
HNQ25_RS22915	COG0672	)-iron permease
HNQ25_RS22930	COG0488	(ABC) transporter
HNQ25_RS22955	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HNQ25_RS22975	COG0181	hydroxymethylbilane synthase activity
HNQ25_RS22985	COG2972	Histidine kinase
HNQ25_RS22985	COG0745	RESPONSE REGULATOR receiver
HNQ25_RS22990	COG0165	Argininosuccinate lyase
HNQ25_RS23035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HNQ25_RS23045	COG1965	Belongs to the frataxin family