locus-tag	class	description
ICJ33_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICJ33_RS00010	COG0592	DNA-directed DNA polymerase activity
ICJ33_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICJ33_RS00020	COG0187	DNA topoisomerase II activity
ICJ33_RS00025	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS00035	COG5002	protein histidine kinase activity
ICJ33_RS00045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICJ33_RS00050	COG0751	glycine-tRNA ligase activity
ICJ33_RS00055	COG0752	glycyl-tRNA synthetase alpha subunit
ICJ33_RS00075	COG0569	domain protein
ICJ33_RS00080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICJ33_RS00085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICJ33_RS00090	COG0242	peptide deformylase activity
ICJ33_RS00100	COG0758	DNA mediated transformation
ICJ33_RS00105	COG0009	L-threonylcarbamoyladenylate synthase
ICJ33_RS00115	COG0408	coproporphyrinogen oxidase activity
ICJ33_RS00120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICJ33_RS00135	COG3119	arylsulfatase activity
ICJ33_RS00140	COG0583	DNA-binding transcription factor activity
ICJ33_RS00150	COG3734	2-keto-3-deoxy-galactonokinase
ICJ33_RS00155	COG0800	Aldolase
ICJ33_RS00160	COG4948	Mandelate Racemase Muconate Lactonizing
ICJ33_RS00165	COG2271	Major facilitator Superfamily
ICJ33_RS00175	COG0159	tryptophan synthase activity
ICJ33_RS00195	COG3360	Dodecin
ICJ33_RS00205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICJ33_RS00210	COG1764	response to oxidative stress
ICJ33_RS00235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICJ33_RS00240	COG0339	signal peptide processing
ICJ33_RS00285	COG0659	secondary active sulfate transmembrane transporter activity
ICJ33_RS00295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICJ33_RS00300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICJ33_RS00305	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ICJ33_RS00335	COG0109	protoheme IX farnesyltransferase activity
ICJ33_RS00345	COG1464	Belongs to the NlpA lipoprotein family
ICJ33_RS00350	COG2011	ABC-type metal ion transport system permease component
ICJ33_RS00355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICJ33_RS00370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ICJ33_RS00375	COG1121	(ABC) transporter
ICJ33_RS00380	COG0735	belongs to the Fur family
ICJ33_RS00385	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ICJ33_RS00405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ICJ33_RS00410	COG3245	cytochrome
ICJ33_RS00420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICJ33_RS00435	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICJ33_RS00440	COG5002	protein histidine kinase activity
ICJ33_RS00445	COG2204	response regulator
ICJ33_RS00455	COG5487	UPF0391 membrane protein
ICJ33_RS00465	COG1301	dicarboxylic acid transport
ICJ33_RS00470	COG0700	Nucleoside recognition
ICJ33_RS00485	COG1127	ABC transporter
ICJ33_RS00490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICJ33_RS00500	COG0612	Peptidase, M16
ICJ33_RS00505	COG1283	sodium-dependent phosphate transmembrane transporter activity
ICJ33_RS00510	COG0861	Integral membrane protein TerC family
ICJ33_RS00515	COG2851	Citrate transporter
ICJ33_RS00550	COG0427	acetyl-CoA hydrolase
ICJ33_RS00570	COG0583	DNA-binding transcription factor activity
ICJ33_RS00575	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS00580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICJ33_RS00615	COG0840	transmembrane signaling receptor activity
ICJ33_RS00625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ICJ33_RS00640	COG1802	Transcriptional regulator
ICJ33_RS00645	COG2175	clavaminate synthase activity
ICJ33_RS00660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICJ33_RS00690	COG1595	DNA-templated transcription, initiation
ICJ33_RS00695	COG3712	iron ion homeostasis
ICJ33_RS00700	COG4774	siderophore transport
ICJ33_RS00750	COG1289	transmembrane transporter activity
ICJ33_RS00760	COG1566	PFAM secretion protein HlyD family protein
ICJ33_RS00775	COG5339	Protein conserved in bacteria
ICJ33_RS00780	COG0457	Tetratricopeptide repeat
ICJ33_RS00785	COG0726	polysaccharide deacetylase
ICJ33_RS00785	COG1649	PFAM Uncharacterised BCR, COG1649
ICJ33_RS00790	COG1215	transferase activity, transferring glycosyl groups
ICJ33_RS00800	COG2831	hemolysin activation secretion protein
ICJ33_RS00845	COG2304	oxidoreductase activity
ICJ33_RS00850	COG1595	DNA-templated transcription, initiation
ICJ33_RS00870	COG0758	DNA mediated transformation
ICJ33_RS00925	COG0582	viral genome integration into host DNA
ICJ33_RS00935	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS00940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICJ33_RS00945	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS00950	COG2199	diguanylate cyclase activity
ICJ33_RS00970	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ICJ33_RS00980	COG4208	sulfate ABC transporter
ICJ33_RS00985	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ICJ33_RS00995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ33_RS01015	COG2807	transmembrane transport
ICJ33_RS01020	COG0583	DNA-binding transcription factor activity
ICJ33_RS01040	COG0765	amino acid transport
ICJ33_RS01045	COG0765	amino acid transport
ICJ33_RS01050	COG1126	abc transporter atp-binding protein
ICJ33_RS01055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS01070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS01075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ33_RS01085	COG2011	ABC-type metal ion transport system permease component
ICJ33_RS01090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICJ33_RS01120	COG1126	abc transporter atp-binding protein
ICJ33_RS01125	COG0765	amino acid transport
ICJ33_RS01130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS01140	COG1045	serine acetyltransferase
ICJ33_RS01145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ICJ33_RS01155	COG0667	Aldo Keto reductase
ICJ33_RS01160	COG2175	clavaminate synthase activity
ICJ33_RS01165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICJ33_RS01170	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ICJ33_RS01175	COG4521	taurine ABC transporter
ICJ33_RS01180	COG2918	glutathione biosynthetic process
ICJ33_RS01190	COG2183	response to ionizing radiation
ICJ33_RS01210	COG4067	protein conserved in archaea
ICJ33_RS01210	COG0189	ligase activity
ICJ33_RS01215	COG2199	diguanylate cyclase activity
ICJ33_RS01215	COG2200	EAL domain
ICJ33_RS01215	COG3287	FIST C domain
ICJ33_RS01220	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ICJ33_RS01230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICJ33_RS01235	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ICJ33_RS01250	COG2184	nucleotidyltransferase activity
ICJ33_RS01265	COG0514	ATP-dependent DNA helicase (RecQ)
ICJ33_RS01270	COG0824	Thioesterase
ICJ33_RS01280	COG0243	molybdopterin cofactor binding
ICJ33_RS01285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ICJ33_RS01295	COG1652	LysM domain
ICJ33_RS01300	COG1011	Hydrolase
ICJ33_RS01305	COG0494	nUDIX hydrolase
ICJ33_RS01310	COG1218	3'(2'),5'-bisphosphate nucleotidase
ICJ33_RS01345	COG1088	dTDP-glucose 4,6-dehydratase activity
ICJ33_RS01350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICJ33_RS01355	COG2957	Belongs to the agmatine deiminase family
ICJ33_RS01375	COG1942	4-Oxalocrotonate Tautomerase
ICJ33_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS01405	COG2342	PFAM TM1410 hypothetical-related protein
ICJ33_RS01430	COG0438	transferase activity, transferring glycosyl groups
ICJ33_RS01455	COG1192	Involved in chromosome partitioning
ICJ33_RS01525	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ICJ33_RS01530	COG1194	a g-specific adenine glycosylase
ICJ33_RS01540	COG2223	nitrite transmembrane transporter activity
ICJ33_RS01545	COG0131	Imidazoleglycerol-phosphate dehydratase
ICJ33_RS01550	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICJ33_RS01560	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICJ33_RS01565	COG0107	imidazoleglycerol-phosphate synthase activity
ICJ33_RS01575	COG2861	carbohydrate metabolic process
ICJ33_RS01580	COG0793	Belongs to the peptidase S41A family
ICJ33_RS01585	COG4942	peptidase
ICJ33_RS01590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICJ33_RS01595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICJ33_RS01605	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ICJ33_RS01625	COG3852	Histidine kinase
ICJ33_RS01645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICJ33_RS01645	COG0301	tRNA thio-modification
ICJ33_RS01650	COG1217	gtp-binding protein TYPA
ICJ33_RS01660	COG0058	SHG alpha-glucan phosphorylase activity
ICJ33_RS01675	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ICJ33_RS01685	COG3040	lipid binding
ICJ33_RS01690	COG0402	S-adenosylhomocysteine deaminase activity
ICJ33_RS01695	COG2188	Transcriptional regulator
ICJ33_RS01705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICJ33_RS01710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ICJ33_RS01720	COG4176	ABC-type proline glycine betaine transport system permease component
ICJ33_RS01725	COG4175	Glycine betaine
ICJ33_RS01725	COG0517	IMP dehydrogenase activity
ICJ33_RS01730	COG2986	histidine ammonia-lyase
ICJ33_RS01735	COG2986	histidine ammonia-lyase
ICJ33_RS01740	COG1113	amino acid transport
ICJ33_RS01745	COG1228	amidohydrolase
ICJ33_RS01765	COG0596	Alpha beta hydrolase
ICJ33_RS01770	COG1490	D-aminoacyl-tRNA deacylase activity
ICJ33_RS01775	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ICJ33_RS01780	COG2943	transferase activity, transferring hexosyl groups
ICJ33_RS01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS01795	COG0765	amino acid transport
ICJ33_RS01800	COG1126	abc transporter atp-binding protein
ICJ33_RS01805	COG0840	transmembrane signaling receptor activity
ICJ33_RS01810	COG0840	transmembrane signaling receptor activity
ICJ33_RS01825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICJ33_RS01830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICJ33_RS01835	COG0140	phosphoribosyl-ATP diphosphatase activity
ICJ33_RS01840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICJ33_RS01845	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ICJ33_RS01855	COG2226	methyltransferase
ICJ33_RS01875	COG1309	transcriptional regulator
ICJ33_RS01900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ICJ33_RS01905	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ICJ33_RS01915	COG0018	arginyl-trna synthetase
ICJ33_RS01920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICJ33_RS01925	COG0254	rRNA binding
ICJ33_RS01935	COG0281	malic enzyme
ICJ33_RS01970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICJ33_RS01975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ICJ33_RS01985	COG0070	glutamate synthase
ICJ33_RS01985	COG0069	glutamate synthase activity
ICJ33_RS01985	COG0067	glutamate synthase
ICJ33_RS01995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ICJ33_RS02000	COG2814	Major facilitator Superfamily
ICJ33_RS02005	COG0583	DNA-binding transcription factor activity
ICJ33_RS02020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ33_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS02035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ33_RS02045	COG2226	methyltransferase
ICJ33_RS02070	COG2986	histidine ammonia-lyase
ICJ33_RS02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ICJ33_RS02095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICJ33_RS02100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICJ33_RS02115	COG1192	Involved in chromosome partitioning
ICJ33_RS02125	COG3118	belongs to the thioredoxin family
ICJ33_RS02130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ICJ33_RS02135	COG3264	Mechanosensitive ion channel
ICJ33_RS02135	COG1196	nuclear chromosome segregation
ICJ33_RS02140	COG3263	regulation of cellular component size
ICJ33_RS02160	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS02165	COG0506	proline dehydrogenase activity
ICJ33_RS02165	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ICJ33_RS02165	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ICJ33_RS02170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICJ33_RS02185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ICJ33_RS02190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICJ33_RS02210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ICJ33_RS02220	COG0859	PFAM glycosyl transferase family 9
ICJ33_RS02225	COG0438	transferase activity, transferring glycosyl groups
ICJ33_RS02250	COG4772	TonB-dependent receptor
ICJ33_RS02260	COG2192	nodulation
ICJ33_RS02275	COG0438	transferase activity, transferring glycosyl groups
ICJ33_RS02280	COG1215	transferase activity, transferring glycosyl groups
ICJ33_RS02290	COG1132	(ABC) transporter
ICJ33_RS02295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ICJ33_RS02295	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ICJ33_RS02300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICJ33_RS02310	COG0667	Aldo Keto reductase
ICJ33_RS02325	COG0583	DNA-binding transcription factor activity
ICJ33_RS02335	COG1538	Outer membrane efflux protein
ICJ33_RS02340	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICJ33_RS02355	COG0494	nUDIX hydrolase
ICJ33_RS02365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ICJ33_RS02370	COG3150	esterase
ICJ33_RS02400	COG3830	Belongs to the UPF0237 family
ICJ33_RS02400	COG0560	Phosphoserine phosphatase
ICJ33_RS02405	COG0688	phosphatidylethanolamine metabolic process
ICJ33_RS02430	COG1162	GTPase activity
ICJ33_RS02435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ICJ33_RS02440	COG2860	membrane
ICJ33_RS02450	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICJ33_RS02450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ICJ33_RS02455	COG0802	atpase or kinase
ICJ33_RS02460	COG0860	N-Acetylmuramoyl-L-alanine amidase
ICJ33_RS02465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICJ33_RS02470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICJ33_RS02475	COG1923	regulation of RNA biosynthetic process
ICJ33_RS02480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICJ33_RS02485	COG0330	HflC and HflK could
ICJ33_RS02490	COG0330	HflC and HflK could
ICJ33_RS02495	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ICJ33_RS02500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICJ33_RS02510	COG1178	ABC-type Fe3 transport system permease component
ICJ33_RS02515	COG1840	ABC-type Fe3 transport system, periplasmic component
ICJ33_RS02535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICJ33_RS02540	COG0360	Binds together with S18 to 16S ribosomal RNA
ICJ33_RS02545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICJ33_RS02555	COG0359	binds to the 23S rRNA
ICJ33_RS02560	COG0305	Participates in initiation and elongation during chromosome replication
ICJ33_RS02565	COG1032	radical SAM domain protein
ICJ33_RS02585	COG2308	Evidence 4 Homologs of previously reported genes of
ICJ33_RS02585	COG2307	Protein conserved in bacteria
ICJ33_RS02605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ICJ33_RS02610	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICJ33_RS02615	COG0583	DNA-binding transcription factor activity
ICJ33_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS02625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS02655	COG4221	oxidoreductase activity
ICJ33_RS02675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ICJ33_RS02680	COG0830	nickel cation binding
ICJ33_RS02685	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ICJ33_RS02690	COG0791	NLP P60 protein
ICJ33_RS02695	COG1309	transcriptional regulator
ICJ33_RS02705	COG2982	Protein involved in outer membrane biogenesis
ICJ33_RS02715	COG0583	DNA-binding transcription factor activity
ICJ33_RS02720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICJ33_RS02725	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ICJ33_RS02730	COG0697	spore germination
ICJ33_RS02735	COG2207	Transcriptional regulator
ICJ33_RS02750	COG0443	Heat shock 70 kDa protein
ICJ33_RS02755	COG0484	heat shock protein binding
ICJ33_RS02760	COG0804	urea catabolic process
ICJ33_RS02765	COG0832	Belongs to the urease beta subunit family
ICJ33_RS02780	COG0831	urea catabolic process
ICJ33_RS02785	COG0829	nickel cation binding
ICJ33_RS02795	COG0411	ABC transporter
ICJ33_RS02820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ33_RS02830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ICJ33_RS02875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICJ33_RS02900	COG2095	MarC family integral membrane protein
ICJ33_RS02910	COG0151	Belongs to the GarS family
ICJ33_RS02915	COG0138	bifunctional purine biosynthesis protein purh
ICJ33_RS02925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICJ33_RS02935	COG2264	protein methyltransferase activity
ICJ33_RS02950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ICJ33_RS02975	COG0023	Translation Initiation Factor
ICJ33_RS02980	COG1166	arginine decarboxylase activity
ICJ33_RS02985	COG0534	Mate efflux family protein
ICJ33_RS02990	COG2373	Large extracellular alpha-helical protein
ICJ33_RS03000	COG4953	penicillin-binding protein 1C
ICJ33_RS03010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICJ33_RS03080	COG4964	Belongs to the GSP D family
ICJ33_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS03135	COG2217	Heavy metal translocating P-type atpase
ICJ33_RS03150	COG2814	Major facilitator Superfamily
ICJ33_RS03160	COG0604	alcohol dehydrogenase
ICJ33_RS03165	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ICJ33_RS03170	COG0583	DNA-binding transcription factor activity
ICJ33_RS03180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ICJ33_RS03185	COG0387	Pfam Sodium calcium exchanger
ICJ33_RS03205	COG1309	transcriptional regulator
ICJ33_RS03210	COG2233	PERMEase
ICJ33_RS03255	COG2995	paraquat-inducible protein a
ICJ33_RS03260	COG2995	paraquat-inducible protein a
ICJ33_RS03265	COG3008	intermembrane lipid transfer
ICJ33_RS03290	COG0456	acetyltransferase
ICJ33_RS03300	COG0288	reversible hydration of carbon dioxide
ICJ33_RS03320	COG2031	fatty acid transporter
ICJ33_RS03325	COG0477	Major facilitator Superfamily
ICJ33_RS03385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ICJ33_RS03405	COG1496	oxidoreductase activity
ICJ33_RS03410	COG0405	Gamma-glutamyltransferase
ICJ33_RS03425	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ICJ33_RS03465	COG1157	protein secretion by the type III secretion system
ICJ33_RS03480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICJ33_RS03490	COG4794	Type iii secretion
ICJ33_RS03500	COG4792	protein secretion
ICJ33_RS03540	COG4669	(LipO)protein
ICJ33_RS03560	COG0012	GTP binding
ICJ33_RS03565	COG0193	aminoacyl-tRNA hydrolase activity
ICJ33_RS03570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ICJ33_RS03575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICJ33_RS03585	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICJ33_RS03590	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ICJ33_RS03600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICJ33_RS03605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICJ33_RS03615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICJ33_RS03620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ICJ33_RS03640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICJ33_RS03655	COG4221	oxidoreductase activity
ICJ33_RS03665	COG0415	Belongs to the DNA photolyase family
ICJ33_RS03670	COG0789	Transcriptional regulator
ICJ33_RS03685	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ICJ33_RS03690	COG1090	epimerase
ICJ33_RS03695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ICJ33_RS03705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICJ33_RS03715	COG0175	sulfate reduction
ICJ33_RS03725	COG0204	Acyl-transferase
ICJ33_RS03730	COG0857	belongs to the CobB CobQ family
ICJ33_RS03730	COG0280	phosphate acetyltransferase
ICJ33_RS03745	COG0268	Binds directly to 16S ribosomal RNA
ICJ33_RS03755	COG0196	riboflavin kinase activity
ICJ33_RS03760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICJ33_RS03765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICJ33_RS03770	COG1047	Peptidyl-prolyl cis-trans
ICJ33_RS03775	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ICJ33_RS03805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS03830	COG0542	response to heat
ICJ33_RS03855	COG1252	NADH dehydrogenase
ICJ33_RS03885	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ICJ33_RS03890	COG0237	dephospho-CoA kinase activity
ICJ33_RS03935	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICJ33_RS03955	COG0084	hydrolase, TatD family'
ICJ33_RS03960	COG1609	Transcriptional regulator
ICJ33_RS03970	COG1105	Belongs to the carbohydrate kinase PfkB family
ICJ33_RS03975	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ICJ33_RS03975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICJ33_RS03975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICJ33_RS03985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ICJ33_RS03990	COG4774	siderophore transport
ICJ33_RS03995	COG3128	pkhd-type hydroxylase
ICJ33_RS04005	COG0019	diaminopimelate decarboxylase activity
ICJ33_RS04030	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICJ33_RS04045	COG4608	Belongs to the ABC transporter superfamily
ICJ33_RS04050	COG0444	Belongs to the ABC transporter superfamily
ICJ33_RS04055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICJ33_RS04060	COG0601	transmembrane transport
ICJ33_RS04065	COG0747	negative chemotaxis
ICJ33_RS04075	COG0747	negative chemotaxis
ICJ33_RS04080	COG0747	negative chemotaxis
ICJ33_RS04085	COG0747	negative chemotaxis
ICJ33_RS04100	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ICJ33_RS04105	COG4178	(ABC) transporter
ICJ33_RS04120	COG0180	Tryptophanyl-tRNA synthetase
ICJ33_RS04125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICJ33_RS04135	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS04140	COG0667	Aldo Keto reductase
ICJ33_RS04145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICJ33_RS04150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ICJ33_RS04155	COG0723	plastoquinol--plastocyanin reductase activity
ICJ33_RS04160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ICJ33_RS04165	COG2857	Cytochrome c1
ICJ33_RS04170	COG0625	glutathione transferase activity
ICJ33_RS04175	COG2969	positive regulation of protein catabolic process
ICJ33_RS04180	COG2186	Transcriptional regulator
ICJ33_RS04195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICJ33_RS04205	COG2271	Major facilitator Superfamily
ICJ33_RS04210	COG2721	sulfolactate sulfo-lyase activity
ICJ33_RS04220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ33_RS04230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICJ33_RS04235	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICJ33_RS04240	COG0154	amidase activity
ICJ33_RS04245	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICJ33_RS04250	COG1077	Cell shape determining protein MreB Mrl
ICJ33_RS04255	COG1792	Involved in formation and maintenance of cell shape
ICJ33_RS04265	COG0424	maF-like protein
ICJ33_RS04270	COG1530	ribonuclease E activity
ICJ33_RS04280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICJ33_RS04285	COG0312	modulator of DNA gyrase
ICJ33_RS04290	COG3028	Belongs to the UPF0307 family
ICJ33_RS04295	COG0312	modulator of DNA gyrase
ICJ33_RS04330	COG1660	Displays ATPase and GTPase activities
ICJ33_RS04340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICJ33_RS04345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ICJ33_RS04350	COG1137	ATPase activity
ICJ33_RS04355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ICJ33_RS04365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ICJ33_RS04375	COG1127	ABC transporter
ICJ33_RS04380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICJ33_RS04385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICJ33_RS04405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICJ33_RS04410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ICJ33_RS04415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICJ33_RS04420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICJ33_RS04430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICJ33_RS04435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ICJ33_RS04495	COG2135	peptidase activity
ICJ33_RS04500	COG0840	transmembrane signaling receptor activity
ICJ33_RS04505	COG0501	Belongs to the peptidase M48B family
ICJ33_RS04510	COG2119	membrane
ICJ33_RS04515	COG2813	Specifically methylates the guanine in position
ICJ33_RS04520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICJ33_RS04525	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS04530	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ33_RS04550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICJ33_RS04555	COG2885	chlorophyll binding
ICJ33_RS04560	COG2823	Periplasmic or secreted lipoprotein
ICJ33_RS04565	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ICJ33_RS04570	COG0792	nuclease activity
ICJ33_RS04590	COG2001	Belongs to the MraZ family
ICJ33_RS04595	COG0275	rRNA processing
ICJ33_RS04610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICJ33_RS04615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ICJ33_RS04620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICJ33_RS04625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICJ33_RS04630	COG0772	Belongs to the SEDS family
ICJ33_RS04635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICJ33_RS04640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICJ33_RS04645	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICJ33_RS04660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICJ33_RS04665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ICJ33_RS04670	COG4251	negative regulation of phosphorylation
ICJ33_RS04670	COG2203	Gaf domain
ICJ33_RS04670	COG5001	Diguanylate cyclase
ICJ33_RS04670	COG3706	GGDEF domain
ICJ33_RS04680	COG5002	protein histidine kinase activity
ICJ33_RS04705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS04720	COG0784	Response regulator, receiver
ICJ33_RS04720	COG0835	chemotaxis
ICJ33_RS04730	COG0583	DNA-binding transcription factor activity
ICJ33_RS04750	COG1566	PFAM secretion protein HlyD family protein
ICJ33_RS04760	COG0477	Major facilitator Superfamily
ICJ33_RS04770	COG0300	oxidoreductase activity
ICJ33_RS04785	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ICJ33_RS04785	COG0662	Cupin 2, conserved barrel domain protein
ICJ33_RS04800	COG1696	Membrane protein involved in D-alanine export
ICJ33_RS04815	COG3420	alginic acid biosynthetic process
ICJ33_RS04825	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ICJ33_RS04830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS04835	COG1215	transferase activity, transferring glycosyl groups
ICJ33_RS04845	COG3022	response to hydroperoxide
ICJ33_RS04855	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ICJ33_RS04860	COG0315	cyclic pyranopterin monophosphate synthase activity
ICJ33_RS04885	COG0513	Belongs to the DEAD box helicase family
ICJ33_RS04890	COG0400	carboxylic ester hydrolase activity
ICJ33_RS04895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS04900	COG4597	amino acid ABC transporter
ICJ33_RS04905	COG0765	amino acid transport
ICJ33_RS04910	COG1126	abc transporter atp-binding protein
ICJ33_RS04915	COG2186	Transcriptional regulator
ICJ33_RS04920	COG2807	transmembrane transport
ICJ33_RS04935	COG3188	usher protein
ICJ33_RS04940	COG3121	Chaperone
ICJ33_RS04965	COG3539	Fimbrial protein
ICJ33_RS04985	COG2827	Endonuclease containing a URI domain
ICJ33_RS04995	COG4774	siderophore transport
ICJ33_RS05000	COG2027	D-alanyl-D-alanine carboxypeptidase
ICJ33_RS05010	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ICJ33_RS05015	COG0179	Fumarylacetoacetate (FAA) hydrolase
ICJ33_RS05035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ICJ33_RS05065	COG0814	amino acid
ICJ33_RS05070	COG1760	l-serine dehydratase
ICJ33_RS05075	COG0583	DNA-binding transcription factor activity
ICJ33_RS05085	COG4772	TonB-dependent receptor
ICJ33_RS05090	COG3712	iron ion homeostasis
ICJ33_RS05095	COG1595	DNA-templated transcription, initiation
ICJ33_RS05120	COG3712	iron ion homeostasis
ICJ33_RS05130	COG3081	Nucleoid-associated protein
ICJ33_RS05140	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ICJ33_RS05145	COG0525	valine-tRNA ligase activity
ICJ33_RS05160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICJ33_RS05165	COG0795	lipopolysaccharide-transporting ATPase activity
ICJ33_RS05170	COG0795	lipopolysaccharide-transporting ATPase activity
ICJ33_RS05175	COG0481	GTPase activity
ICJ33_RS05180	COG0681	Belongs to the peptidase S26 family
ICJ33_RS05185	COG0571	ribonuclease III activity
ICJ33_RS05190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICJ33_RS05195	COG1381	Involved in DNA repair and RecF pathway recombination
ICJ33_RS05200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ICJ33_RS05210	COG0590	tRNA wobble adenosine to inosine editing
ICJ33_RS05215	COG0500	methyltransferase
ICJ33_RS05220	COG2226	methyltransferase
ICJ33_RS05235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICJ33_RS05275	COG0523	cobalamin synthesis protein
ICJ33_RS05295	COG4206	TonB-dependent receptor
ICJ33_RS05320	COG3188	usher protein
ICJ33_RS05325	COG3121	Chaperone
ICJ33_RS05345	COG3539	Fimbrial protein
ICJ33_RS05355	COG2375	cellular response to nickel ion
ICJ33_RS05360	COG1695	Transcriptional regulator
ICJ33_RS05390	COG1113	amino acid transport
ICJ33_RS05405	COG0069	glutamate synthase activity
ICJ33_RS05415	COG2205	protein histidine kinase activity
ICJ33_RS05420	COG1858	cytochrome C peroxidase
ICJ33_RS05445	COG0583	DNA-binding transcription factor activity
ICJ33_RS05455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ33_RS05475	COG2076	Multidrug Resistance protein
ICJ33_RS05495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICJ33_RS05510	COG4191	Histidine kinase
ICJ33_RS05515	COG2204	response regulator
ICJ33_RS05535	COG1126	abc transporter atp-binding protein
ICJ33_RS05540	COG0765	amino acid transport
ICJ33_RS05545	COG0765	amino acid transport
ICJ33_RS05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS05565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICJ33_RS05575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICJ33_RS05580	COG3842	ATPase activity
ICJ33_RS05585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICJ33_RS05590	COG0243	molybdopterin cofactor binding
ICJ33_RS05595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICJ33_RS05610	COG0450	alkyl hydroperoxide reductase
ICJ33_RS05620	COG0418	dihydroorotase activity
ICJ33_RS05630	COG0137	argininosuccinate synthase activity
ICJ33_RS05635	COG2197	response regulator
ICJ33_RS05645	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICJ33_RS05650	COG2878	Part of a membrane complex involved in electron transport
ICJ33_RS05655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICJ33_RS05655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICJ33_RS05660	COG0489	protein tyrosine kinase activity
ICJ33_RS05665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICJ33_RS05670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICJ33_RS05780	COG3179	chitinase
ICJ33_RS05790	COG1546	Belongs to the CinA family
ICJ33_RS05795	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICJ33_RS05800	COG2137	regulation of response to DNA damage stimulus
ICJ33_RS05815	COG3148	PFAM DTW domain containing protein
ICJ33_RS05830	COG0583	DNA-binding transcription factor activity
ICJ33_RS05845	COG4807	Protein conserved in bacteria
ICJ33_RS05860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICJ33_RS05865	COG3158	transport of potassium into the cell
ICJ33_RS05870	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS05875	COG2311	Membrane
ICJ33_RS05890	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ICJ33_RS05895	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ICJ33_RS05900	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS05905	COG1177	transmembrane transport
ICJ33_RS05910	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICJ33_RS05915	COG3842	ATPase activity
ICJ33_RS05920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ICJ33_RS05930	COG0583	DNA-binding transcription factor activity
ICJ33_RS05940	COG0840	transmembrane signaling receptor activity
ICJ33_RS05950	COG0457	Tetratricopeptide repeat
ICJ33_RS05950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICJ33_RS05965	COG2201	protein-glutamate methylesterase activity
ICJ33_RS05970	COG5001	Diguanylate cyclase
ICJ33_RS05970	COG4251	negative regulation of phosphorylation
ICJ33_RS05970	COG3706	GGDEF domain
ICJ33_RS05970	COG2203	Gaf domain
ICJ33_RS05980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ICJ33_RS06000	COG1073	alpha beta
ICJ33_RS06020	COG2885	chlorophyll binding
ICJ33_RS06035	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ICJ33_RS06040	COG0563	adenylate kinase activity
ICJ33_RS06045	COG1214	PFAM Peptidase M22, glycoprotease
ICJ33_RS06075	COG0742	ribosomal rna small subunit methyltransferase
ICJ33_RS06085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS06105	COG2937	Belongs to the GPAT DAPAT family
ICJ33_RS06120	COG2226	methyltransferase
ICJ33_RS06125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICJ33_RS06130	COG1215	transferase activity, transferring glycosyl groups
ICJ33_RS06135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ICJ33_RS06140	COG2166	iron-sulfur cluster assembly
ICJ33_RS06145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICJ33_RS06150	COG2171	N-acyltransferase activity
ICJ33_RS06155	COG1393	Belongs to the ArsC family
ICJ33_RS06160	COG0582	viral genome integration into host DNA
ICJ33_RS06215	COG5532	Uncharacterized conserved protein (DUF2303)
ICJ33_RS06290	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ICJ33_RS06340	COG4626	Terminase
ICJ33_RS06340	COG1802	Transcriptional regulator
ICJ33_RS06350	COG0740	serine-type endopeptidase activity
ICJ33_RS06450	COG3179	chitinase
ICJ33_RS06465	COG0025	NhaP-type Na H and K H
ICJ33_RS06470	COG0436	Aminotransferase
ICJ33_RS06475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ICJ33_RS06485	COG0052	Belongs to the universal ribosomal protein uS2 family
ICJ33_RS06490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICJ33_RS06495	COG0528	UMP kinase activity
ICJ33_RS06500	COG0233	cytoplasmic translational termination
ICJ33_RS06505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICJ33_RS06515	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ICJ33_RS06535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ33_RS06540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ICJ33_RS06545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ33_RS06550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ33_RS06555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICJ33_RS06560	COG0587	DNA-directed DNA polymerase activity
ICJ33_RS06565	COG0825	malonyl-CoA metabolic process
ICJ33_RS06570	COG0037	tRNA processing
ICJ33_RS06575	COG0504	CTP synthase activity
ICJ33_RS06580	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ICJ33_RS06585	COG0148	phosphopyruvate hydratase activity
ICJ33_RS06595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ICJ33_RS06605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ICJ33_RS06610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ICJ33_RS06615	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ICJ33_RS06620	COG0585	pseudouridine synthase activity
ICJ33_RS06625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ICJ33_RS06630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ICJ33_RS06655	COG1278	Cold shock
ICJ33_RS06660	COG0717	Belongs to the dCTP deaminase family
ICJ33_RS06675	COG1201	RNA secondary structure unwinding
ICJ33_RS06705	COG1793	dna ligase
ICJ33_RS06715	COG2366	antibiotic biosynthetic process
ICJ33_RS06720	COG0625	glutathione transferase activity
ICJ33_RS06725	COG1120	ATPase activity
ICJ33_RS06730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ33_RS06745	COG4774	siderophore transport
ICJ33_RS06760	COG0653	protein targeting
ICJ33_RS06770	COG3012	SEC-C Motif Domain Protein
ICJ33_RS06795	COG1199	ATP-dependent helicase activity
ICJ33_RS06815	COG0259	pyridoxamine-phosphate oxidase activity
ICJ33_RS06825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ICJ33_RS06835	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ICJ33_RS06850	COG0583	DNA-binding transcription factor activity
ICJ33_RS06865	COG3220	belongs to the UPF0276 family
ICJ33_RS06920	COG2271	Major facilitator Superfamily
ICJ33_RS06925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ICJ33_RS06945	COG0583	DNA-binding transcription factor activity
ICJ33_RS06955	COG0306	phosphate transporter
ICJ33_RS06970	COG2814	Major facilitator Superfamily
ICJ33_RS06975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICJ33_RS06980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ICJ33_RS06985	COG0183	Belongs to the thiolase family
ICJ33_RS06990	COG3485	protocatechuate 3,4-dioxygenase
ICJ33_RS06995	COG3485	protocatechuate 3,4-dioxygenase
ICJ33_RS07000	COG0477	Major facilitator Superfamily
ICJ33_RS07010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ33_RS07015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ33_RS07045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS07050	COG1309	transcriptional regulator
ICJ33_RS07055	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS07060	COG2814	Major facilitator Superfamily
ICJ33_RS07120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ33_RS07130	COG1704	LemA family
ICJ33_RS07150	COG0697	spore germination
ICJ33_RS07155	COG1629	transport
ICJ33_RS07165	COG1595	DNA-templated transcription, initiation
ICJ33_RS07175	COG0235	Class ii aldolase
ICJ33_RS07180	COG1396	sequence-specific DNA binding
ICJ33_RS07190	COG1454	alcohol dehydrogenase
ICJ33_RS07200	COG0156	8-amino-7-oxononanoate synthase activity
ICJ33_RS07215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICJ33_RS07225	COG2271	Major facilitator Superfamily
ICJ33_RS07250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICJ33_RS07255	COG0583	DNA-binding transcription factor activity
ICJ33_RS07260	COG2814	Major facilitator Superfamily
ICJ33_RS07290	COG2267	carboxylic ester hydrolase activity
ICJ33_RS07320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICJ33_RS07380	COG0642	Histidine kinase
ICJ33_RS07395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ICJ33_RS07425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICJ33_RS07435	COG0425	Belongs to the sulfur carrier protein TusA family
ICJ33_RS07445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICJ33_RS07455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICJ33_RS07460	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ICJ33_RS07465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ICJ33_RS07470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ICJ33_RS07490	COG0583	DNA-binding transcription factor activity
ICJ33_RS07495	COG0477	Major facilitator Superfamily
ICJ33_RS07510	COG0583	DNA-binding transcription factor activity
ICJ33_RS07530	COG1802	Transcriptional regulator
ICJ33_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS07540	COG3246	L-lysine catabolic process to acetate
ICJ33_RS07575	COG2807	transmembrane transport
ICJ33_RS07580	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS07590	COG0583	DNA-binding transcription factor activity
ICJ33_RS07595	COG2910	NAD(P)H-binding
ICJ33_RS07605	COG0583	DNA-binding transcription factor activity
ICJ33_RS07635	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ICJ33_RS07645	COG0583	DNA-binding transcription factor activity
ICJ33_RS07655	COG0174	glutamine synthetase
ICJ33_RS07670	COG3100	YcgL domain-containing protein
ICJ33_RS07675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICJ33_RS07690	COG2983	Belongs to the UPF0260 family
ICJ33_RS07735	COG1770	oligopeptidase
ICJ33_RS07745	COG0121	glutamine amidotransferase
ICJ33_RS07755	COG0583	DNA-binding transcription factor activity
ICJ33_RS07760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ICJ33_RS07765	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ICJ33_RS07770	COG1984	allophanate hydrolase subunit 2
ICJ33_RS07785	COG0542	response to heat
ICJ33_RS07795	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICJ33_RS07810	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ICJ33_RS07815	COG0425	Belongs to the sulfur carrier protein TusA family
ICJ33_RS07825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICJ33_RS07835	COG1132	(ABC) transporter
ICJ33_RS07840	COG0741	lytic transglycosylase activity
ICJ33_RS07845	COG0488	(ABC) transporter
ICJ33_RS07850	COG0589	response to stress
ICJ33_RS07860	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICJ33_RS07860	COG1024	Enoyl-CoA hydratase
ICJ33_RS07865	COG0183	Belongs to the thiolase family
ICJ33_RS07910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ICJ33_RS07920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICJ33_RS07935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICJ33_RS07940	COG0584	glycerophosphoryl diester phosphodiesterase
ICJ33_RS07950	COG4591	ABC-type transport system involved in lipoprotein release permease component
ICJ33_RS07955	COG1136	(ABC) transporter
ICJ33_RS07960	COG4591	ABC-type transport system involved in lipoprotein release permease component
ICJ33_RS07980	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICJ33_RS07980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICJ33_RS07995	COG2853	Lipoprotein
ICJ33_RS08005	COG2204	response regulator
ICJ33_RS08015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICJ33_RS08020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICJ33_RS08025	COG0582	viral genome integration into host DNA
ICJ33_RS08080	COG2814	Major facilitator Superfamily
ICJ33_RS08085	COG0579	oxidoreductase
ICJ33_RS08090	COG0583	DNA-binding transcription factor activity
ICJ33_RS08125	COG1611	Belongs to the LOG family
ICJ33_RS08135	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ICJ33_RS08155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICJ33_RS08160	COG0583	DNA-binding transcription factor activity
ICJ33_RS08165	COG2814	Major facilitator Superfamily
ICJ33_RS08175	COG2233	PERMEase
ICJ33_RS08185	COG2197	response regulator
ICJ33_RS08190	COG0596	Alpha beta hydrolase
ICJ33_RS08200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICJ33_RS08205	COG0444	Belongs to the ABC transporter superfamily
ICJ33_RS08215	COG0747	negative chemotaxis
ICJ33_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS08225	COG0546	phosphoglycolate phosphatase activity
ICJ33_RS08230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICJ33_RS08235	COG0402	S-adenosylhomocysteine deaminase activity
ICJ33_RS08240	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICJ33_RS08250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICJ33_RS08260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICJ33_RS08265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICJ33_RS08270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ICJ33_RS08285	COG0776	regulation of translation
ICJ33_RS08295	COG1086	Polysaccharide biosynthesis protein
ICJ33_RS08370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICJ33_RS08375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICJ33_RS08375	COG0543	2 iron, 2 sulfur cluster binding
ICJ33_RS08380	COG1555	photosystem II stabilization
ICJ33_RS08415	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ICJ33_RS08425	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ICJ33_RS08430	COG2205	protein histidine kinase activity
ICJ33_RS08435	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS08470	COG3209	COG3209 Rhs family protein
ICJ33_RS08470	COG3209	COG3209 Rhs family protein
ICJ33_RS08480	COG0084	hydrolase, TatD family'
ICJ33_RS08485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ICJ33_RS08490	COG2259	Doxx family
ICJ33_RS08520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ33_RS08525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ICJ33_RS08530	COG4181	ATPase activity
ICJ33_RS08545	COG1376	ErfK ybiS ycfS ynhG family protein
ICJ33_RS08575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICJ33_RS08595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ33_RS08610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICJ33_RS08620	COG1764	response to oxidative stress
ICJ33_RS08625	COG1846	Transcriptional regulator
ICJ33_RS08630	COG0583	DNA-binding transcription factor activity
ICJ33_RS08635	COG0730	response to heat
ICJ33_RS08640	COG0583	DNA-binding transcription factor activity
ICJ33_RS08650	COG3214	Protein conserved in bacteria
ICJ33_RS08655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ICJ33_RS08675	COG3384	dioxygenase
ICJ33_RS08680	COG0500	methyltransferase
ICJ33_RS08685	COG0501	Belongs to the peptidase M48B family
ICJ33_RS08690	COG0436	Aminotransferase
ICJ33_RS08695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICJ33_RS08700	COG0386	Belongs to the glutathione peroxidase family
ICJ33_RS08705	COG1846	Transcriptional regulator
ICJ33_RS08710	COG5002	protein histidine kinase activity
ICJ33_RS08710	COG0784	Response regulator, receiver
ICJ33_RS08710	COG2205	protein histidine kinase activity
ICJ33_RS08720	COG1956	GAF domain-containing protein
ICJ33_RS08725	COG2205	protein histidine kinase activity
ICJ33_RS08725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS08730	COG2197	response regulator
ICJ33_RS08765	COG0004	ammonium transporteR
ICJ33_RS08785	COG0564	pseudouridine synthase activity
ICJ33_RS08795	COG0746	molybdenum cofactor guanylyltransferase activity
ICJ33_RS08800	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICJ33_RS08805	COG0303	'Molybdopterin
ICJ33_RS08810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICJ33_RS08820	COG4133	protoheme IX ABC transporter activity
ICJ33_RS08840	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ICJ33_RS08845	COG1138	Cytochrome C-type biogenesis protein
ICJ33_RS08855	COG3088	subunit of a heme lyase
ICJ33_RS08860	COG4235	cytochrome complex assembly
ICJ33_RS08870	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ICJ33_RS08895	COG2814	Major facilitator Superfamily
ICJ33_RS08905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ICJ33_RS08910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ33_RS08920	COG0469	pyruvate kinase activity
ICJ33_RS08930	COG2084	Dehydrogenase
ICJ33_RS08935	COG3622	Belongs to the hyi family
ICJ33_RS08940	COG3960	tartronate-semialdehyde synthase activity
ICJ33_RS08955	COG1309	transcriptional regulator
ICJ33_RS08960	COG2354	Protein conserved in bacteria
ICJ33_RS08965	COG2853	Lipoprotein
ICJ33_RS08985	COG2113	Glycine betaine
ICJ33_RS08990	COG3162	membrane
ICJ33_RS08995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICJ33_RS09005	COG2009	succinate dehydrogenase
ICJ33_RS09010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ICJ33_RS09015	COG1053	succinate dehydrogenase
ICJ33_RS09020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ICJ33_RS09035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICJ33_RS09040	COG0045	succinate-CoA ligase (ADP-forming) activity
ICJ33_RS09075	COG0326	Molecular chaperone. Has ATPase activity
ICJ33_RS09100	COG0840	transmembrane signaling receptor activity
ICJ33_RS09110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ICJ33_RS09115	COG2205	protein histidine kinase activity
ICJ33_RS09115	COG0784	Response regulator, receiver
ICJ33_RS09115	COG5002	protein histidine kinase activity
ICJ33_RS09130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ICJ33_RS09145	COG1022	Amp-dependent synthetase and ligase
ICJ33_RS09185	COG0284	orotidine-5'-phosphate decarboxylase activity
ICJ33_RS09190	COG2130	NADP-dependent
ICJ33_RS09205	COG0840	transmembrane signaling receptor activity
ICJ33_RS09210	COG2267	carboxylic ester hydrolase activity
ICJ33_RS09255	COG0556	nucleotide-excision repair
ICJ33_RS09300	COG0811	peptide transport
ICJ33_RS09320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICJ33_RS09325	COG3540	Alkaline phosphatase
ICJ33_RS09330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICJ33_RS09355	COG0625	glutathione transferase activity
ICJ33_RS09360	COG1131	(ABC) transporter
ICJ33_RS09365	COG0842	Transport permease protein
ICJ33_RS09395	COG2076	Multidrug Resistance protein
ICJ33_RS09400	COG0385	Bile acid
ICJ33_RS09405	COG2974	May be involved in recombination
ICJ33_RS09450	COG2010	Cytochrome c
ICJ33_RS09455	COG0545	Peptidyl-prolyl cis-trans isomerase
ICJ33_RS09475	COG2200	EAL domain
ICJ33_RS09485	COG3321	synthase
ICJ33_RS09485	COG4221	oxidoreductase activity
ICJ33_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ICJ33_RS09485	COG0604	alcohol dehydrogenase
ICJ33_RS09495	COG3842	ATPase activity
ICJ33_RS09505	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICJ33_RS09530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ICJ33_RS09535	COG1121	(ABC) transporter
ICJ33_RS09565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICJ33_RS09570	COG0066	3-isopropylmalate dehydratase activity
ICJ33_RS09575	COG0583	DNA-binding transcription factor activity
ICJ33_RS09580	COG1301	dicarboxylic acid transport
ICJ33_RS09585	COG0596	Alpha beta hydrolase
ICJ33_RS09605	COG3829	transcription factor binding
ICJ33_RS09615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICJ33_RS09620	COG0431	NADPH-dependent FMN reductase
ICJ33_RS09640	COG0583	DNA-binding transcription factor activity
ICJ33_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS09665	COG5006	permease, DMT superfamily
ICJ33_RS09695	COG0768	penicillin binding
ICJ33_RS09720	COG0417	DNA replication proofreading
ICJ33_RS09745	COG0728	peptidoglycan biosynthetic process
ICJ33_RS09790	COG0662	Cupin 2, conserved barrel domain protein
ICJ33_RS09790	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ICJ33_RS09795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ICJ33_RS09810	COG3712	iron ion homeostasis
ICJ33_RS09830	COG4977	sequence-specific DNA binding
ICJ33_RS09845	COG3387	PFAM Glycoside hydrolase 15-related
ICJ33_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS09855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICJ33_RS09860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICJ33_RS09870	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS09900	COG1595	DNA-templated transcription, initiation
ICJ33_RS09910	COG4772	TonB-dependent receptor
ICJ33_RS09925	COG2223	nitrite transmembrane transporter activity
ICJ33_RS09955	COG0402	S-adenosylhomocysteine deaminase activity
ICJ33_RS09965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ICJ33_RS09970	COG1051	belongs to the nudix hydrolase family
ICJ33_RS09980	COG1476	TRANSCRIPTIONal
ICJ33_RS09990	COG0720	synthase
ICJ33_RS10020	COG0840	transmembrane signaling receptor activity
ICJ33_RS10025	COG2056	Na+-H+ antiporter family
ICJ33_RS10030	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICJ33_RS10040	COG0826	peptidase U32
ICJ33_RS10060	COG4566	intracellular signal transduction
ICJ33_RS10070	COG4191	Histidine kinase
ICJ33_RS10075	COG1764	response to oxidative stress
ICJ33_RS10085	COG2814	Major facilitator Superfamily
ICJ33_RS10090	COG0596	Alpha beta hydrolase
ICJ33_RS10100	COG2807	transmembrane transport
ICJ33_RS10105	COG2207	Transcriptional regulator
ICJ33_RS10120	COG0753	catalase activity
ICJ33_RS10125	COG1764	response to oxidative stress
ICJ33_RS10140	COG0628	permease
ICJ33_RS10160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICJ33_RS10165	COG3132	Protein of unknown function, DUF480
ICJ33_RS10175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ICJ33_RS10185	COG0583	DNA-binding transcription factor activity
ICJ33_RS10195	COG1253	flavin adenine dinucleotide binding
ICJ33_RS10200	COG0709	Synthesizes selenophosphate from selenide and ATP
ICJ33_RS10205	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ICJ33_RS10210	COG0701	Predicted permease
ICJ33_RS10220	COG0625	glutathione transferase activity
ICJ33_RS10225	COG0384	phenazine biosynthesis protein PhzF
ICJ33_RS10230	COG0113	porphobilinogen synthase activity
ICJ33_RS10235	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS10265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICJ33_RS10270	COG0583	DNA-binding transcription factor activity
ICJ33_RS10280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ICJ33_RS10285	COG0517	IMP dehydrogenase activity
ICJ33_RS10290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICJ33_RS10315	COG4335	DNA alkylation repair
ICJ33_RS10320	COG0174	glutamine synthetase
ICJ33_RS10335	COG2814	Major facilitator Superfamily
ICJ33_RS10365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICJ33_RS10390	COG2197	response regulator
ICJ33_RS10395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS10395	COG2205	protein histidine kinase activity
ICJ33_RS10405	COG0656	L-ascorbic acid biosynthetic process
ICJ33_RS10415	COG1024	Enoyl-CoA hydratase
ICJ33_RS10420	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS10435	COG2249	NAD(P)H dehydrogenase (quinone) activity
ICJ33_RS10440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICJ33_RS10465	COG0322	excinuclease ABC activity
ICJ33_RS10480	COG0582	viral genome integration into host DNA
ICJ33_RS10515	COG0784	Response regulator, receiver
ICJ33_RS10515	COG4191	Histidine kinase
ICJ33_RS10530	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS10530	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICJ33_RS10535	COG2113	Glycine betaine
ICJ33_RS10545	COG2271	Major facilitator Superfamily
ICJ33_RS10560	COG5002	protein histidine kinase activity
ICJ33_RS10565	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS10605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICJ33_RS10640	COG4214	carbohydrate transport
ICJ33_RS10645	COG1129	ABC transporter
ICJ33_RS10650	COG4213	ABC transporter substrate-binding protein
ICJ33_RS10655	COG2115	Belongs to the xylose isomerase family
ICJ33_RS10660	COG2207	Transcriptional regulator
ICJ33_RS10660	COG1609	Transcriptional regulator
ICJ33_RS10680	COG3781	membrane
ICJ33_RS10690	COG0640	Transcriptional regulator
ICJ33_RS10695	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS10725	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS10735	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS10740	COG1129	ABC transporter
ICJ33_RS10745	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS10765	COG2207	Transcriptional regulator
ICJ33_RS10775	COG0625	glutathione transferase activity
ICJ33_RS10790	COG0673	inositol 2-dehydrogenase activity
ICJ33_RS10830	COG1968	undecaprenyl-diphosphatase activity
ICJ33_RS10840	COG0747	negative chemotaxis
ICJ33_RS10875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ICJ33_RS10890	COG1309	transcriptional regulator
ICJ33_RS10900	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS10905	COG0604	alcohol dehydrogenase
ICJ33_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS10905	COG3321	synthase
ICJ33_RS10940	COG1064	alcohol dehydrogenase
ICJ33_RS11045	COG1522	sequence-specific DNA binding
ICJ33_RS11090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICJ33_RS11100	COG0583	DNA-binding transcription factor activity
ICJ33_RS11130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICJ33_RS11130	COG0475	glutathione-regulated potassium exporter activity
ICJ33_RS11135	COG1396	sequence-specific DNA binding
ICJ33_RS11140	COG0697	spore germination
ICJ33_RS11145	COG0367	asparagine synthase
ICJ33_RS11155	COG1024	Enoyl-CoA hydratase
ICJ33_RS11160	COG2207	Transcriptional regulator
ICJ33_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS11280	COG1177	transmembrane transport
ICJ33_RS11285	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICJ33_RS11290	COG3842	ATPase activity
ICJ33_RS11295	COG1414	Transcriptional regulator
ICJ33_RS11305	COG2205	protein histidine kinase activity
ICJ33_RS11305	COG2198	Histidine kinase
ICJ33_RS11305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS11305	COG0784	Response regulator, receiver
ICJ33_RS11325	COG3842	ATPase activity
ICJ33_RS11340	COG0114	fumarate hydratase activity
ICJ33_RS11345	COG1301	dicarboxylic acid transport
ICJ33_RS11375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICJ33_RS11385	COG0534	Mate efflux family protein
ICJ33_RS11390	COG1309	transcriptional regulator
ICJ33_RS11455	COG1522	sequence-specific DNA binding
ICJ33_RS11460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ33_RS11475	COG3284	Transcriptional regulator
ICJ33_RS11480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ICJ33_RS11485	COG0022	dehydrogenase e1 component
ICJ33_RS11500	COG0174	glutamine synthetase
ICJ33_RS11510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS11515	COG0583	DNA-binding transcription factor activity
ICJ33_RS11525	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS11535	COG5002	protein histidine kinase activity
ICJ33_RS11540	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS11565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICJ33_RS11575	COG3718	enzyme involved in inositol metabolism
ICJ33_RS11590	COG0673	inositol 2-dehydrogenase activity
ICJ33_RS11595	COG0673	inositol 2-dehydrogenase activity
ICJ33_RS11605	COG1129	ABC transporter
ICJ33_RS11610	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS11670	COG4774	siderophore transport
ICJ33_RS11690	COG5001	Diguanylate cyclase
ICJ33_RS11690	COG4251	negative regulation of phosphorylation
ICJ33_RS11690	COG2203	Gaf domain
ICJ33_RS11690	COG3706	GGDEF domain
ICJ33_RS11710	COG1595	DNA-templated transcription, initiation
ICJ33_RS11735	COG0616	signal peptide processing
ICJ33_RS11745	COG0583	DNA-binding transcription factor activity
ICJ33_RS11755	COG2376	Dihydroxyacetone kinase
ICJ33_RS11760	COG1063	alcohol dehydrogenase
ICJ33_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS11770	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS11775	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS11780	COG1129	ABC transporter
ICJ33_RS11785	COG0698	ribose 5-phosphate isomerase
ICJ33_RS11795	COG1253	flavin adenine dinucleotide binding
ICJ33_RS11815	COG0765	amino acid transport
ICJ33_RS11820	COG0765	amino acid transport
ICJ33_RS11850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICJ33_RS11860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICJ33_RS11865	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS11870	COG2610	gluconate transmembrane transporter activity
ICJ33_RS11875	COG3290	protein histidine kinase activity
ICJ33_RS11875	COG3829	transcription factor binding
ICJ33_RS11880	COG4172	Belongs to the ABC transporter superfamily
ICJ33_RS11885	COG4239	(ABC) transporter, permease
ICJ33_RS11890	COG4174	ABC transporter (Permease)
ICJ33_RS11895	COG4166	transmembrane transport
ICJ33_RS11900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICJ33_RS11905	COG4172	Belongs to the ABC transporter superfamily
ICJ33_RS11910	COG4239	(ABC) transporter, permease
ICJ33_RS11915	COG4174	ABC transporter (Permease)
ICJ33_RS11920	COG4166	transmembrane transport
ICJ33_RS11925	COG4166	transmembrane transport
ICJ33_RS11930	COG0741	lytic transglycosylase activity
ICJ33_RS11930	COG1388	LysM domain
ICJ33_RS11935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICJ33_RS11945	COG0328	RNA-DNA hybrid ribonuclease activity
ICJ33_RS11950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICJ33_RS11960	COG0456	acetyltransferase
ICJ33_RS11980	COG0431	NADPH-dependent FMN reductase
ICJ33_RS11985	COG0028	Belongs to the TPP enzyme family
ICJ33_RS11995	COG0789	Transcriptional regulator
ICJ33_RS12010	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS12030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ICJ33_RS12030	COG0316	Belongs to the HesB IscA family
ICJ33_RS12080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ33_RS12095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICJ33_RS12100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICJ33_RS12110	COG3139	Protein of unknown function (DUF1315)
ICJ33_RS12120	COG0308	aminopeptidase N
ICJ33_RS12125	COG0667	Aldo Keto reductase
ICJ33_RS12140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICJ33_RS12160	COG2194	sulfuric ester hydrolase activity
ICJ33_RS12170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ICJ33_RS12175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICJ33_RS12180	COG0561	phosphatase activity
ICJ33_RS12270	COG2233	PERMEase
ICJ33_RS12290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICJ33_RS12300	COG1609	Transcriptional regulator
ICJ33_RS12315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS12320	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS12325	COG2205	protein histidine kinase activity
ICJ33_RS12335	COG1595	DNA-templated transcription, initiation
ICJ33_RS12350	COG0730	response to heat
ICJ33_RS12360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICJ33_RS12370	COG0189	ligase activity
ICJ33_RS12375	COG0598	Magnesium transport protein CorA
ICJ33_RS12380	COG0024	Methionine aminopeptidase
ICJ33_RS12390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICJ33_RS12415	COG1070	Carbohydrate kinase
ICJ33_RS12435	COG1175	transmembrane transport
ICJ33_RS12480	COG1538	Outer membrane efflux protein
ICJ33_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS12500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS12505	COG0348	domain, Protein
ICJ33_RS12515	COG1285	pathogenesis
ICJ33_RS12535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICJ33_RS12545	COG4191	Histidine kinase
ICJ33_RS12545	COG0784	Response regulator, receiver
ICJ33_RS12555	COG2814	Major facilitator Superfamily
ICJ33_RS12585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICJ33_RS12590	COG3318	Belongs to the UPF0149 family
ICJ33_RS12590	COG3012	SEC-C Motif Domain Protein
ICJ33_RS12595	COG0038	chloride channel
ICJ33_RS12600	COG1024	Enoyl-CoA hydratase
ICJ33_RS12605	COG2816	NAD+ diphosphatase activity
ICJ33_RS12635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICJ33_RS12660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICJ33_RS12665	COG1595	DNA-templated transcription, initiation
ICJ33_RS12670	COG3712	iron ion homeostasis
ICJ33_RS12675	COG1116	anion transmembrane transporter activity
ICJ33_RS12680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICJ33_RS12685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS12695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ICJ33_RS12700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICJ33_RS12710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ33_RS12725	COG2271	Major facilitator Superfamily
ICJ33_RS12730	COG1335	isochorismatase
ICJ33_RS12735	COG3473	Maleate cis-trans isomerase
ICJ33_RS12740	COG0596	Alpha beta hydrolase
ICJ33_RS12745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICJ33_RS12750	COG2309	aminopeptidase activity
ICJ33_RS12755	COG1846	Transcriptional regulator
ICJ33_RS12760	COG2080	2 iron, 2 sulfur cluster binding
ICJ33_RS12765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ICJ33_RS12765	COG2010	Cytochrome c
ICJ33_RS12770	COG1309	transcriptional regulator
ICJ33_RS12790	COG0840	transmembrane signaling receptor activity
ICJ33_RS12795	COG1968	undecaprenyl-diphosphatase activity
ICJ33_RS12810	COG0583	DNA-binding transcription factor activity
ICJ33_RS12815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICJ33_RS12830	COG0488	(ABC) transporter
ICJ33_RS12860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ICJ33_RS12870	COG2133	pyrroloquinoline quinone binding
ICJ33_RS12885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ33_RS12890	COG2822	iron ion transport
ICJ33_RS12900	COG2822	iron ion transport
ICJ33_RS12905	COG0672	)-iron permease
ICJ33_RS12930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS12950	COG1021	2,3-dihydroxybenzoate-AMP ligase
ICJ33_RS12985	COG1132	(ABC) transporter
ICJ33_RS12990	COG1132	(ABC) transporter
ICJ33_RS12990	COG2375	cellular response to nickel ion
ICJ33_RS13000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ICJ33_RS13000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ICJ33_RS13020	COG4771	TonB-dependent receptor
ICJ33_RS13035	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS13055	COG4948	Mandelate Racemase Muconate Lactonizing
ICJ33_RS13070	COG0667	Aldo Keto reductase
ICJ33_RS13080	COG0477	Major facilitator Superfamily
ICJ33_RS13100	COG2207	Transcriptional regulator
ICJ33_RS13105	COG0300	oxidoreductase activity
ICJ33_RS13120	COG3321	synthase
ICJ33_RS13120	COG0604	alcohol dehydrogenase
ICJ33_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS13130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS13145	COG0210	DNA helicase
ICJ33_RS13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS13180	COG1113	amino acid transport
ICJ33_RS13225	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ICJ33_RS13245	COG2267	carboxylic ester hydrolase activity
ICJ33_RS13260	COG2308	Evidence 4 Homologs of previously reported genes of
ICJ33_RS13300	COG0697	spore germination
ICJ33_RS13335	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS13355	COG3038	cytochrome b561
ICJ33_RS13365	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS13370	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS13375	COG1609	Transcriptional regulator
ICJ33_RS13380	COG1070	Carbohydrate kinase
ICJ33_RS13385	COG1522	sequence-specific DNA binding
ICJ33_RS13395	COG0826	peptidase U32
ICJ33_RS13405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ33_RS13425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ICJ33_RS13465	COG1196	nuclear chromosome segregation
ICJ33_RS13515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICJ33_RS13535	COG3121	Chaperone
ICJ33_RS13565	COG3539	Fimbrial protein
ICJ33_RS13570	COG3121	Chaperone
ICJ33_RS13575	COG3188	usher protein
ICJ33_RS13590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ICJ33_RS13595	COG3710	Transcriptional regulator
ICJ33_RS13625	COG3188	usher protein
ICJ33_RS13630	COG3121	Chaperone
ICJ33_RS13650	COG2197	response regulator
ICJ33_RS13655	COG1509	lysine 2,3-aminomutase activity
ICJ33_RS13740	COG1360	Flagellar Motor Protein
ICJ33_RS13750	COG2067	long-chain fatty acid transport protein
ICJ33_RS13760	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICJ33_RS13815	COG2814	Major facilitator Superfamily
ICJ33_RS13825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ICJ33_RS13835	COG0463	Glycosyl transferase, family 2
ICJ33_RS13840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICJ33_RS13840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICJ33_RS13845	COG0726	polysaccharide deacetylase
ICJ33_RS13850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICJ33_RS13855	COG2076	Multidrug Resistance protein
ICJ33_RS13860	COG2076	Multidrug Resistance protein
ICJ33_RS13880	COG1024	Enoyl-CoA hydratase
ICJ33_RS13885	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS13890	COG1024	Enoyl-CoA hydratase
ICJ33_RS13895	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS13900	COG0183	Belongs to the thiolase family
ICJ33_RS13910	COG3781	membrane
ICJ33_RS13920	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ICJ33_RS13935	COG2205	protein histidine kinase activity
ICJ33_RS13935	COG5002	protein histidine kinase activity
ICJ33_RS13935	COG0784	Response regulator, receiver
ICJ33_RS13945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICJ33_RS13950	COG0784	Response regulator, receiver
ICJ33_RS13950	COG2198	Histidine kinase
ICJ33_RS13950	COG2205	protein histidine kinase activity
ICJ33_RS13975	COG3278	Belongs to the heme-copper respiratory oxidase family
ICJ33_RS13985	COG1794	racemase activity, acting on amino acids and derivatives
ICJ33_RS13990	COG1247	-acetyltransferase
ICJ33_RS14015	COG1929	Belongs to the glycerate kinase type-1 family
ICJ33_RS14020	COG3835	regulator
ICJ33_RS14025	COG2271	Major facilitator Superfamily
ICJ33_RS14035	COG0583	DNA-binding transcription factor activity
ICJ33_RS14040	COG0667	Aldo Keto reductase
ICJ33_RS14060	COG0583	DNA-binding transcription factor activity
ICJ33_RS14145	COG3145	DNA-N1-methyladenine dioxygenase activity
ICJ33_RS14150	COG2169	Transcriptional regulator
ICJ33_RS14150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICJ33_RS14170	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ICJ33_RS14180	COG0488	(ABC) transporter
ICJ33_RS14200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ICJ33_RS14210	COG0640	Transcriptional regulator
ICJ33_RS14220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICJ33_RS14225	COG0431	NADPH-dependent FMN reductase
ICJ33_RS14230	COG2207	Transcriptional regulator
ICJ33_RS14230	COG1917	Cupin 2, conserved barrel domain protein
ICJ33_RS14305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ICJ33_RS14310	COG0581	inorganic phosphate transmembrane transporter activity
ICJ33_RS14320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICJ33_RS14350	COG0531	amino acid
ICJ33_RS14355	COG3938	Belongs to the proline racemase family
ICJ33_RS14370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS14385	COG0583	DNA-binding transcription factor activity
ICJ33_RS14395	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS14430	COG2366	antibiotic biosynthetic process
ICJ33_RS14445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICJ33_RS14450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS14455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS14455	COG1116	anion transmembrane transporter activity
ICJ33_RS14475	COG0583	DNA-binding transcription factor activity
ICJ33_RS14480	COG0667	Aldo Keto reductase
ICJ33_RS14500	COG1238	metal cluster binding
ICJ33_RS14510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICJ33_RS14515	COG0297	glycogen (starch) synthase activity
ICJ33_RS14520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICJ33_RS14525	COG1640	4-alpha-glucanotransferase
ICJ33_RS14580	COG1113	amino acid transport
ICJ33_RS14590	COG1522	sequence-specific DNA binding
ICJ33_RS14620	COG2814	Major facilitator Superfamily
ICJ33_RS14625	COG0583	DNA-binding transcription factor activity
ICJ33_RS14630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICJ33_RS14670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICJ33_RS14675	COG1944	ATP diphosphatase activity
ICJ33_RS14710	COG0583	DNA-binding transcription factor activity
ICJ33_RS14735	COG1247	-acetyltransferase
ICJ33_RS14755	COG2146	nitrite reductase [NAD(P)H] activity
ICJ33_RS14755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICJ33_RS14760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICJ33_RS14760	COG2146	nitrite reductase [NAD(P)H] activity
ICJ33_RS14765	COG0243	molybdopterin cofactor binding
ICJ33_RS14795	COG1846	Transcriptional regulator
ICJ33_RS14795	COG0456	acetyltransferase
ICJ33_RS14800	COG2271	Major facilitator Superfamily
ICJ33_RS14805	COG0519	Catalyzes the synthesis of GMP from XMP
ICJ33_RS14820	COG3300	MHYT domain
ICJ33_RS14820	COG5001	Diguanylate cyclase
ICJ33_RS14825	COG2207	Transcriptional regulator
ICJ33_RS14830	COG2223	nitrite transmembrane transporter activity
ICJ33_RS14835	COG3300	MHYT domain
ICJ33_RS14835	COG5001	Diguanylate cyclase
ICJ33_RS14880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS14885	COG0697	spore germination
ICJ33_RS14890	COG2353	YceI-like domain
ICJ33_RS14940	COG2079	MmgE PrpD family protein
ICJ33_RS14945	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS14950	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ICJ33_RS14955	COG0583	DNA-binding transcription factor activity
ICJ33_RS14975	COG0714	Associated with various cellular activities
ICJ33_RS14980	COG3791	Glutathione-dependent formaldehyde-activating
ICJ33_RS15000	COG2205	protein histidine kinase activity
ICJ33_RS15005	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS15020	COG0589	response to stress
ICJ33_RS15035	COG0814	amino acid
ICJ33_RS15060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICJ33_RS15070	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS15075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ33_RS15090	COG2818	Glycosylase
ICJ33_RS15125	COG0714	Associated with various cellular activities
ICJ33_RS15155	COG0420	3'-5' exonuclease activity
ICJ33_RS15175	COG2706	6-phosphogluconolactonase activity
ICJ33_RS15200	COG0673	inositol 2-dehydrogenase activity
ICJ33_RS15205	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ33_RS15210	COG0183	Belongs to the thiolase family
ICJ33_RS15220	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS15225	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS15255	COG3239	Fatty acid desaturase
ICJ33_RS15260	COG2267	carboxylic ester hydrolase activity
ICJ33_RS15280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ICJ33_RS15290	COG0515	serine threonine protein kinase
ICJ33_RS15370	COG0656	L-ascorbic acid biosynthetic process
ICJ33_RS15385	COG0596	Alpha beta hydrolase
ICJ33_RS15395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICJ33_RS15400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICJ33_RS15435	COG0625	glutathione transferase activity
ICJ33_RS15465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ICJ33_RS15470	COG3842	ATPase activity
ICJ33_RS15475	COG1177	transmembrane transport
ICJ33_RS15480	COG1175	transmembrane transport
ICJ33_RS15490	COG1609	Transcriptional regulator
ICJ33_RS15495	COG0019	diaminopimelate decarboxylase activity
ICJ33_RS15510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS15515	COG0765	amino acid transport
ICJ33_RS15520	COG1126	abc transporter atp-binding protein
ICJ33_RS15525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS15535	COG2066	Belongs to the glutaminase family
ICJ33_RS15555	COG2207	Transcriptional regulator
ICJ33_RS15565	COG0673	inositol 2-dehydrogenase activity
ICJ33_RS15585	COG5383	Protein conserved in bacteria
ICJ33_RS15605	COG4191	Histidine kinase
ICJ33_RS15605	COG0784	Response regulator, receiver
ICJ33_RS15610	COG0587	DNA-directed DNA polymerase activity
ICJ33_RS15625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICJ33_RS15630	COG3209	COG3209 Rhs family protein
ICJ33_RS15630	COG3209	COG3209 Rhs family protein
ICJ33_RS15650	COG0494	nUDIX hydrolase
ICJ33_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS15670	COG1349	DNA-binding transcription factor activity
ICJ33_RS15690	COG0693	protein deglycase activity
ICJ33_RS15715	COG0840	transmembrane signaling receptor activity
ICJ33_RS15730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICJ33_RS15730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICJ33_RS15745	COG2181	nitrate reductase activity
ICJ33_RS15750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ICJ33_RS15755	COG1140	nitrate reductase beta subunit
ICJ33_RS15760	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICJ33_RS15765	COG2223	nitrite transmembrane transporter activity
ICJ33_RS15780	COG2197	response regulator
ICJ33_RS15785	COG3154	lipid carrier protein
ICJ33_RS15790	COG0826	peptidase U32
ICJ33_RS15795	COG0826	peptidase U32
ICJ33_RS15800	COG0303	'Molybdopterin
ICJ33_RS15805	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICJ33_RS15840	COG1999	signal sequence binding
ICJ33_RS15860	COG0589	response to stress
ICJ33_RS15865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ33_RS15875	COG0589	response to stress
ICJ33_RS15890	COG1063	alcohol dehydrogenase
ICJ33_RS15930	COG1595	DNA-templated transcription, initiation
ICJ33_RS15950	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS15980	COG2814	Major facilitator Superfamily
ICJ33_RS15990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ33_RS15995	COG3209	COG3209 Rhs family protein
ICJ33_RS16010	COG3706	GGDEF domain
ICJ33_RS16045	COG0235	Class ii aldolase
ICJ33_RS16050	COG0583	DNA-binding transcription factor activity
ICJ33_RS16060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICJ33_RS16065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS16075	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS16095	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ICJ33_RS16105	COG5002	protein histidine kinase activity
ICJ33_RS16105	COG3447	MASE1 domain protein
ICJ33_RS16105	COG5001	Diguanylate cyclase
ICJ33_RS16115	COG0583	DNA-binding transcription factor activity
ICJ33_RS16120	COG1335	isochorismatase
ICJ33_RS16140	COG4977	sequence-specific DNA binding
ICJ33_RS16140	COG1917	Cupin 2, conserved barrel domain protein
ICJ33_RS16160	COG1741	Belongs to the pirin family
ICJ33_RS16170	COG1116	anion transmembrane transporter activity
ICJ33_RS16175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICJ33_RS16190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS16195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS16210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ICJ33_RS16215	COG2814	Major facilitator Superfamily
ICJ33_RS16255	COG0395	ABC-type sugar transport system, permease component
ICJ33_RS16265	COG3842	ATPase activity
ICJ33_RS16270	COG3842	ATPase activity
ICJ33_RS16275	COG3284	Transcriptional regulator
ICJ33_RS16285	COG1595	DNA-templated transcription, initiation
ICJ33_RS16400	COG3237	CsbD-like
ICJ33_RS16415	COG0583	DNA-binding transcription factor activity
ICJ33_RS16470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICJ33_RS16520	COG0673	inositol 2-dehydrogenase activity
ICJ33_RS16525	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS16555	COG2323	membrane
ICJ33_RS16560	COG0531	amino acid
ICJ33_RS16575	COG2169	Transcriptional regulator
ICJ33_RS16575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICJ33_RS16620	COG1414	Transcriptional regulator
ICJ33_RS16630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICJ33_RS16635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICJ33_RS16645	COG2851	Citrate transporter
ICJ33_RS16685	COG2135	peptidase activity
ICJ33_RS16780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ICJ33_RS16785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICJ33_RS16790	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ICJ33_RS16795	COG2835	tetraacyldisaccharide 4'-kinase activity
ICJ33_RS16800	COG1663	tetraacyldisaccharide 4'-kinase activity
ICJ33_RS16805	COG0848	biopolymer transport protein
ICJ33_RS16810	COG0811	peptide transport
ICJ33_RS16815	COG0658	competence protein
ICJ33_RS16815	COG2333	competence protein COMEC
ICJ33_RS16840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICJ33_RS16860	COG1393	Belongs to the ArsC family
ICJ33_RS16880	COG0037	tRNA processing
ICJ33_RS16890	COG3091	SprT-like family
ICJ33_RS16895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICJ33_RS16915	COG2920	part of a sulfur-relay system
ICJ33_RS16920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICJ33_RS16925	COG0435	Glutathione S-transferase
ICJ33_RS16930	COG1648	precorrin-2 dehydrogenase activity
ICJ33_RS16930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ICJ33_RS16940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICJ33_RS16945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ICJ33_RS16950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ICJ33_RS16955	COG1674	ftsk spoiiie
ICJ33_RS16965	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ICJ33_RS16970	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ICJ33_RS16975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICJ33_RS16980	COG0542	response to heat
ICJ33_RS16985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ICJ33_RS16990	COG1278	Cold shock
ICJ33_RS17010	COG0482	sulfurtransferase activity
ICJ33_RS17015	COG2915	High frequency lysogenization protein hflD homolog
ICJ33_RS17025	COG2850	peptidyl-arginine hydroxylation
ICJ33_RS17030	COG2153	protein acetylation
ICJ33_RS17040	COG2224	Isocitrate lyase
ICJ33_RS17045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ33_RS17050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ33_RS17055	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ33_RS17055	COG0649	NAD binding
ICJ33_RS17070	COG1034	ATP synthesis coupled electron transport
ICJ33_RS17075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ICJ33_RS17080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICJ33_RS17090	COG0713	ATP synthesis coupled electron transport
ICJ33_RS17105	COG1007	ATP synthesis coupled electron transport
ICJ33_RS17110	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ICJ33_RS17155	COG2814	Major facilitator Superfamily
ICJ33_RS17170	COG3220	belongs to the UPF0276 family
ICJ33_RS17215	COG1136	(ABC) transporter
ICJ33_RS17215	COG0577	efflux transmembrane transporter activity
ICJ33_RS17220	COG1136	(ABC) transporter
ICJ33_RS17220	COG0577	efflux transmembrane transporter activity
ICJ33_RS17230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS17295	COG2111	Na H antiporter
ICJ33_RS17295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ICJ33_RS17300	COG1006	Multisubunit Na H antiporter MnhC subunit
ICJ33_RS17305	COG0651	ATP synthesis coupled electron transport
ICJ33_RS17315	COG2212	antiporter activity
ICJ33_RS17320	COG1320	monovalent cation:proton antiporter activity
ICJ33_RS17330	COG1733	regulation of RNA biosynthetic process
ICJ33_RS17350	COG3340	Belongs to the peptidase S51 family
ICJ33_RS17355	COG0215	cysteine-tRNA ligase activity
ICJ33_RS17360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICJ33_RS17370	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICJ33_RS17375	COG2814	Major facilitator Superfamily
ICJ33_RS17380	COG1566	PFAM secretion protein HlyD family protein
ICJ33_RS17390	COG1846	Transcriptional regulator
ICJ33_RS17395	COG2205	protein histidine kinase activity
ICJ33_RS17395	COG0784	Response regulator, receiver
ICJ33_RS17400	COG5001	Diguanylate cyclase
ICJ33_RS17400	COG3300	MHYT domain
ICJ33_RS17410	COG2197	response regulator
ICJ33_RS17420	COG3121	Chaperone
ICJ33_RS17430	COG2911	Protein conserved in bacteria
ICJ33_RS17435	COG0729	surface antigen
ICJ33_RS17445	COG0708	Exodeoxyribonuclease III
ICJ33_RS17450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICJ33_RS17455	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS17465	COG0789	Transcriptional regulator
ICJ33_RS17475	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ33_RS17480	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS17485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ICJ33_RS17510	COG2866	Carboxypeptidase
ICJ33_RS17520	COG2814	Major facilitator Superfamily
ICJ33_RS17525	COG3038	cytochrome b561
ICJ33_RS17590	COG0217	transcriptional regulatory protein
ICJ33_RS17605	COG0583	DNA-binding transcription factor activity
ICJ33_RS17610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ICJ33_RS17615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICJ33_RS17620	COG3038	cytochrome b561
ICJ33_RS17630	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS17630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICJ33_RS17645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ICJ33_RS17650	COG1846	Transcriptional regulator
ICJ33_RS17655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ICJ33_RS17665	COG0583	DNA-binding transcription factor activity
ICJ33_RS17670	COG2814	Major facilitator Superfamily
ICJ33_RS17680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICJ33_RS17685	COG0776	regulation of translation
ICJ33_RS17690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICJ33_RS17695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICJ33_RS17700	COG0740	serine-type endopeptidase activity
ICJ33_RS17705	COG0544	peptidyl-prolyl cis-trans isomerase activity
ICJ33_RS17730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICJ33_RS17735	COG1686	Belongs to the peptidase S11 family
ICJ33_RS17760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS17780	COG1953	Uracil, thiamine, allantoin
ICJ33_RS17790	COG0493	'glutamate synthase
ICJ33_RS17790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICJ33_RS17800	COG1309	transcriptional regulator
ICJ33_RS17815	COG1276	copper resistance
ICJ33_RS17825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICJ33_RS17835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ICJ33_RS17870	COG4221	oxidoreductase activity
ICJ33_RS17875	COG0471	metal ion transport
ICJ33_RS17880	COG4191	Histidine kinase
ICJ33_RS17905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICJ33_RS17940	COG4585	Histidine kinase
ICJ33_RS17955	COG1131	(ABC) transporter
ICJ33_RS17975	COG2205	protein histidine kinase activity
ICJ33_RS17975	COG0784	Response regulator, receiver
ICJ33_RS17995	COG0640	Transcriptional regulator
ICJ33_RS18005	COG1522	sequence-specific DNA binding
ICJ33_RS18010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ICJ33_RS18015	COG0022	dehydrogenase e1 component
ICJ33_RS18025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICJ33_RS18030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICJ33_RS18035	COG0456	acetyltransferase
ICJ33_RS18045	COG2423	ornithine cyclodeaminase activity
ICJ33_RS18055	COG4215	(ABC) transporter
ICJ33_RS18095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS18100	COG1136	(ABC) transporter
ICJ33_RS18100	COG0577	efflux transmembrane transporter activity
ICJ33_RS18115	COG2186	Transcriptional regulator
ICJ33_RS18160	COG1609	Transcriptional regulator
ICJ33_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS18170	COG1070	Carbohydrate kinase
ICJ33_RS18175	COG1063	alcohol dehydrogenase
ICJ33_RS18180	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS18190	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS18240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICJ33_RS18265	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS18270	COG3384	dioxygenase
ICJ33_RS18280	COG2271	Major facilitator Superfamily
ICJ33_RS18285	COG3971	2-oxopent-4-enoate hydratase activity
ICJ33_RS18295	COG1846	Transcriptional regulator
ICJ33_RS18320	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS18335	COG0531	amino acid
ICJ33_RS18350	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS18355	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS18360	COG0251	oxidation-reduction process
ICJ33_RS18385	COG0583	DNA-binding transcription factor activity
ICJ33_RS18395	COG0625	glutathione transferase activity
ICJ33_RS18400	COG0390	transport system, permease component
ICJ33_RS18405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ICJ33_RS18450	COG1450	Type ii and iii secretion system protein
ICJ33_RS18465	COG3166	PFAM Fimbrial assembly family protein
ICJ33_RS18470	COG3156	type II secretion system protein K
ICJ33_RS18480	COG2165	general secretion pathway protein
ICJ33_RS18485	COG2165	general secretion pathway protein
ICJ33_RS18490	COG2165	general secretion pathway protein
ICJ33_RS18495	COG1459	type II secretion system
ICJ33_RS18500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICJ33_RS18505	COG1120	ATPase activity
ICJ33_RS18510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ33_RS18515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ33_RS18520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ICJ33_RS18525	COG4774	siderophore transport
ICJ33_RS18540	COG0765	amino acid transport
ICJ33_RS18545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS18560	COG2205	protein histidine kinase activity
ICJ33_RS18565	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS18570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICJ33_RS18600	COG0179	Fumarylacetoacetate (FAA) hydrolase
ICJ33_RS18670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICJ33_RS18675	COG1309	transcriptional regulator
ICJ33_RS18685	COG1063	alcohol dehydrogenase
ICJ33_RS18690	COG2853	Lipoprotein
ICJ33_RS18700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ33_RS18710	COG2205	protein histidine kinase activity
ICJ33_RS18715	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS18730	COG0776	regulation of translation
ICJ33_RS18735	COG0072	phenylalanine-tRNA ligase activity
ICJ33_RS18740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICJ33_RS18745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICJ33_RS18750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ICJ33_RS18755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICJ33_RS18760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICJ33_RS18770	COG1278	Cold shock
ICJ33_RS18795	COG1869	D-ribose catabolic process
ICJ33_RS18800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICJ33_RS18805	COG1609	Transcriptional regulator
ICJ33_RS18810	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS18815	COG1129	ABC transporter
ICJ33_RS18820	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS18845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICJ33_RS18860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICJ33_RS18880	COG5002	protein histidine kinase activity
ICJ33_RS18920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS18955	COG1286	toxin biosynthetic process
ICJ33_RS18960	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICJ33_RS18965	COG0285	dihydrofolate synthase activity
ICJ33_RS18970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICJ33_RS18975	COG0135	phosphoribosylanthranilate isomerase activity
ICJ33_RS19000	COG0473	3-isopropylmalate dehydrogenase activity
ICJ33_RS19005	COG2226	methyltransferase
ICJ33_RS19010	COG0066	3-isopropylmalate dehydratase activity
ICJ33_RS19015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICJ33_RS19045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICJ33_RS19055	COG0596	Alpha beta hydrolase
ICJ33_RS19085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICJ33_RS19090	COG0556	nucleotide-excision repair
ICJ33_RS19105	COG0583	DNA-binding transcription factor activity
ICJ33_RS19110	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS19125	COG1864	DNA RNA non-specific endonuclease
ICJ33_RS19125	COG3591	Belongs to the peptidase S1B family
ICJ33_RS19130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICJ33_RS19135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ33_RS19140	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ICJ33_RS19160	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ICJ33_RS19180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICJ33_RS19190	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS19195	COG0583	DNA-binding transcription factor activity
ICJ33_RS19210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICJ33_RS19245	COG4104	PAAR repeat-containing protein
ICJ33_RS19280	COG2384	SAM-dependent methyltransferase
ICJ33_RS19285	COG2186	Transcriptional regulator
ICJ33_RS19300	COG4521	taurine ABC transporter
ICJ33_RS19320	COG0235	Class ii aldolase
ICJ33_RS19330	COG5285	phytanoyl-CoA dioxygenase
ICJ33_RS19335	COG1126	abc transporter atp-binding protein
ICJ33_RS19340	COG0583	DNA-binding transcription factor activity
ICJ33_RS19350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ICJ33_RS19360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICJ33_RS19375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS19380	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ICJ33_RS19390	COG2391	methyltransferase activity
ICJ33_RS19415	COG1309	transcriptional regulator
ICJ33_RS19430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ICJ33_RS19435	COG0436	Aminotransferase
ICJ33_RS19440	COG1301	dicarboxylic acid transport
ICJ33_RS19455	COG1301	dicarboxylic acid transport
ICJ33_RS19460	COG0583	DNA-binding transcription factor activity
ICJ33_RS19465	COG0640	Transcriptional regulator
ICJ33_RS19485	COG1192	Involved in chromosome partitioning
ICJ33_RS19495	COG0583	DNA-binding transcription factor activity
ICJ33_RS19500	COG1304	FMN binding
ICJ33_RS19515	COG5001	Diguanylate cyclase
ICJ33_RS19515	COG5002	protein histidine kinase activity
ICJ33_RS19530	COG1054	Belongs to the UPF0176 family
ICJ33_RS19560	COG0271	Belongs to the BolA IbaG family
ICJ33_RS19570	COG0114	fumarate hydratase activity
ICJ33_RS19575	COG0697	spore germination
ICJ33_RS19580	COG0183	Belongs to the thiolase family
ICJ33_RS19585	COG2326	polyphosphate kinase activity
ICJ33_RS19595	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ICJ33_RS19595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS19600	COG0367	asparagine synthase
ICJ33_RS19605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICJ33_RS19605	COG0189	ligase activity
ICJ33_RS19610	COG1363	Peptidase, m42
ICJ33_RS19615	COG3089	Belongs to the UPF0270 family
ICJ33_RS19620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICJ33_RS19635	COG1368	sulfuric ester hydrolase activity
ICJ33_RS19660	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ33_RS19670	COG2197	response regulator
ICJ33_RS19675	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ICJ33_RS19685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICJ33_RS19690	COG1073	alpha beta
ICJ33_RS19715	COG2840	Smr protein MutS2
ICJ33_RS19720	COG0302	gtp cyclohydrolase
ICJ33_RS19740	COG2851	Citrate transporter
ICJ33_RS19745	COG0583	DNA-binding transcription factor activity
ICJ33_RS19750	COG0625	glutathione transferase activity
ICJ33_RS19755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS19765	COG2252	PERMEase
ICJ33_RS19795	COG4266	Belongs to the allantoicase family
ICJ33_RS19800	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ICJ33_RS19810	COG2233	PERMEase
ICJ33_RS19830	COG1560	Kdo2-lipid A biosynthetic process
ICJ33_RS19835	COG0850	regulation of cytokinetic process
ICJ33_RS19840	COG2894	cell division
ICJ33_RS19845	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ICJ33_RS19850	COG0564	pseudouridine synthase activity
ICJ33_RS19855	COG1362	aminopeptidase activity
ICJ33_RS19865	COG0668	transmembrane transport
ICJ33_RS19885	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICJ33_RS19890	COG0642	Histidine kinase
ICJ33_RS19905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICJ33_RS19955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ICJ33_RS19960	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS19980	COG3123	guanosine phosphorylase activity
ICJ33_RS19985	COG3217	Mosc domain protein beta barrel domain protein
ICJ33_RS19985	COG0633	Ferredoxin
ICJ33_RS20000	COG3851	Histidine kinase
ICJ33_RS20005	COG2197	response regulator
ICJ33_RS20010	COG1597	lipid kinase activity
ICJ33_RS20030	COG1192	Involved in chromosome partitioning
ICJ33_RS20035	COG1360	Flagellar Motor Protein
ICJ33_RS20040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ICJ33_RS20045	COG2201	protein-glutamate methylesterase activity
ICJ33_RS20050	COG2198	Histidine kinase
ICJ33_RS20050	COG0784	Response regulator, receiver
ICJ33_RS20050	COG0643	Histidine kinase
ICJ33_RS20055	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ICJ33_RS20085	COG1278	Cold shock
ICJ33_RS20090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICJ33_RS20140	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS20175	COG1677	Flagellar hook-basal body complex protein FliE
ICJ33_RS20205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ICJ33_RS20230	COG1256	bacterial-type flagellum assembly
ICJ33_RS20240	COG1706	bacterial-type flagellum-dependent cell motility
ICJ33_RS20245	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ICJ33_RS20255	COG4787	bacterial-type flagellum-dependent cell motility
ICJ33_RS20270	COG2154	pterin-4-alpha-carbinolamine dehydratase
ICJ33_RS20285	COG2207	Transcriptional regulator
ICJ33_RS20310	COG1846	Transcriptional regulator
ICJ33_RS20315	COG0514	ATP-dependent DNA helicase (RecQ)
ICJ33_RS20325	COG2832	Protein of unknown function (DUF454)
ICJ33_RS20330	COG2205	protein histidine kinase activity
ICJ33_RS20330	COG0784	Response regulator, receiver
ICJ33_RS20375	COG1846	Transcriptional regulator
ICJ33_RS20380	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ICJ33_RS20385	COG0406	alpha-ribazole phosphatase activity
ICJ33_RS20390	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ICJ33_RS20400	COG1492	cobalamin metabolic process
ICJ33_RS20410	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ICJ33_RS20415	COG0778	Nitroreductase
ICJ33_RS20420	COG1797	cobyrinic acid a,c-diamide synthase activity
ICJ33_RS20430	COG0791	NLP P60 protein
ICJ33_RS20435	COG0791	NLP P60 protein
ICJ33_RS20440	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICJ33_RS20445	COG0628	permease
ICJ33_RS20455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ICJ33_RS20460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICJ33_RS20475	COG3122	Protein conserved in bacteria
ICJ33_RS20480	COG3956	TIGRFAM MazG family protein
ICJ33_RS20485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICJ33_RS20490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICJ33_RS20530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICJ33_RS20535	COG0583	DNA-binding transcription factor activity
ICJ33_RS20545	COG1953	Uracil, thiamine, allantoin
ICJ33_RS20555	COG2996	Protein conserved in bacteria
ICJ33_RS20605	COG0513	Belongs to the DEAD box helicase family
ICJ33_RS20610	COG0668	transmembrane transport
ICJ33_RS20620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICJ33_RS20645	COG1132	(ABC) transporter
ICJ33_RS20650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ICJ33_RS20660	COG2188	Transcriptional regulator
ICJ33_RS20670	COG1595	DNA-templated transcription, initiation
ICJ33_RS20680	COG1643	Atp-dependent helicase
ICJ33_RS20685	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ICJ33_RS20730	COG0463	Glycosyl transferase, family 2
ICJ33_RS20760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICJ33_RS20765	COG0543	2 iron, 2 sulfur cluster binding
ICJ33_RS20765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICJ33_RS20780	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ICJ33_RS20785	COG0438	transferase activity, transferring glycosyl groups
ICJ33_RS20810	COG0840	transmembrane signaling receptor activity
ICJ33_RS20820	COG3278	Belongs to the heme-copper respiratory oxidase family
ICJ33_RS20840	COG3278	Belongs to the heme-copper respiratory oxidase family
ICJ33_RS20855	COG2010	Cytochrome c
ICJ33_RS20870	COG0348	domain, Protein
ICJ33_RS20905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICJ33_RS20910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICJ33_RS20915	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS20920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICJ33_RS20925	COG2130	NADP-dependent
ICJ33_RS20930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICJ33_RS20950	COG0583	DNA-binding transcription factor activity
ICJ33_RS20985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICJ33_RS20990	COG3115	cell septum assembly
ICJ33_RS21010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ICJ33_RS21020	COG0402	S-adenosylhomocysteine deaminase activity
ICJ33_RS21025	COG1802	Transcriptional regulator
ICJ33_RS21030	COG3135	benzoate transporter
ICJ33_RS21035	COG3171	Protein conserved in bacteria
ICJ33_RS21050	COG0116	Belongs to the methyltransferase superfamily
ICJ33_RS21050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICJ33_RS21055	COG3130	regulation of translation
ICJ33_RS21060	COG0167	dihydroorotate dehydrogenase activity
ICJ33_RS21075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICJ33_RS21085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS21085	COG1116	anion transmembrane transporter activity
ICJ33_RS21090	COG3707	response regulator
ICJ33_RS21095	COG2223	nitrite transmembrane transporter activity
ICJ33_RS21105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ICJ33_RS21110	COG3047	cAMP biosynthetic process
ICJ33_RS21110	COG2885	chlorophyll binding
ICJ33_RS21135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ICJ33_RS21150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ICJ33_RS21155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS21170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICJ33_RS21175	COG1045	serine acetyltransferase
ICJ33_RS21180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICJ33_RS21195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICJ33_RS21200	COG0372	Belongs to the citrate synthase family
ICJ33_RS21210	COG1802	Transcriptional regulator
ICJ33_RS21215	COG0189	ligase activity
ICJ33_RS21215	COG4067	protein conserved in archaea
ICJ33_RS21225	COG0189	ligase activity
ICJ33_RS21230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICJ33_RS21245	COG0560	Phosphoserine phosphatase
ICJ33_RS21255	COG1953	Uracil, thiamine, allantoin
ICJ33_RS21265	COG0583	DNA-binding transcription factor activity
ICJ33_RS21270	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS21275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICJ33_RS21340	COG0598	Magnesium transport protein CorA
ICJ33_RS21345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICJ33_RS21345	COG0519	Catalyzes the synthesis of GMP from XMP
ICJ33_RS21350	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICJ33_RS21350	COG1024	Enoyl-CoA hydratase
ICJ33_RS21355	COG0183	Belongs to the thiolase family
ICJ33_RS21365	COG1305	Transglutaminase-like
ICJ33_RS21375	COG2308	Evidence 4 Homologs of previously reported genes of
ICJ33_RS21405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS21410	COG2885	chlorophyll binding
ICJ33_RS21440	COG2207	Transcriptional regulator
ICJ33_RS21445	COG1064	alcohol dehydrogenase
ICJ33_RS21450	COG1414	Transcriptional regulator
ICJ33_RS21455	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICJ33_RS21460	COG1129	ABC transporter
ICJ33_RS21465	COG1879	ABC-type sugar transport system periplasmic component
ICJ33_RS21470	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS21505	COG1397	ADP-ribosylglycohydrolase
ICJ33_RS21510	COG2188	Transcriptional regulator
ICJ33_RS21535	COG0084	hydrolase, TatD family'
ICJ33_RS21545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICJ33_RS21550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICJ33_RS21560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICJ33_RS21565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICJ33_RS21580	COG0416	fatty acid biosynthetic process
ICJ33_RS21585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ICJ33_RS21590	COG1399	metal-binding, possibly nucleic acid-binding protein
ICJ33_RS21595	COG0424	maF-like protein
ICJ33_RS21600	COG0616	signal peptide processing
ICJ33_RS21600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ICJ33_RS21605	COG0546	phosphoglycolate phosphatase activity
ICJ33_RS21615	COG1530	ribonuclease E activity
ICJ33_RS21620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICJ33_RS21625	COG3608	succinylglutamate desuccinylase aspartoacylase
ICJ33_RS21625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ICJ33_RS21630	COG1301	dicarboxylic acid transport
ICJ33_RS21635	COG1917	Cupin 2, conserved barrel domain protein
ICJ33_RS21635	COG4977	sequence-specific DNA binding
ICJ33_RS21655	COG2977	Belongs to the P-Pant transferase superfamily
ICJ33_RS21660	COG2205	protein histidine kinase activity
ICJ33_RS21665	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS21685	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ICJ33_RS21690	COG1558	bacterial-type flagellum-dependent cell motility
ICJ33_RS21695	COG1815	bacterial-type flagellum-dependent cell motility
ICJ33_RS21700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICJ33_RS21705	COG0835	chemotaxis
ICJ33_RS21705	COG0784	Response regulator, receiver
ICJ33_RS21725	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ICJ33_RS21730	COG0477	Major facilitator Superfamily
ICJ33_RS21755	COG2239	Acts as a magnesium transporter
ICJ33_RS21775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICJ33_RS21780	COG0527	aspartate kinase activity
ICJ33_RS21785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICJ33_RS21790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ICJ33_RS21795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ICJ33_RS21805	COG2988	succinylglutamate desuccinylase activity
ICJ33_RS21815	COG3724	N-succinylarginine dihydrolase activity
ICJ33_RS21820	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS21835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICJ33_RS21870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS21875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICJ33_RS21885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICJ33_RS21900	COG0165	Argininosuccinate lyase
ICJ33_RS21905	COG0765	amino acid transport
ICJ33_RS21920	COG2814	Major facilitator Superfamily
ICJ33_RS21935	COG0154	amidase activity
ICJ33_RS21955	COG3706	GGDEF domain
ICJ33_RS21975	COG0504	CTP synthase activity
ICJ33_RS21980	COG2329	Antibiotic biosynthesis monooxygenase
ICJ33_RS21990	COG0584	glycerophosphoryl diester phosphodiesterase
ICJ33_RS22015	COG0306	phosphate transporter
ICJ33_RS22020	COG1984	allophanate hydrolase subunit 2
ICJ33_RS22030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ICJ33_RS22040	COG0583	DNA-binding transcription factor activity
ICJ33_RS22045	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS22055	COG0583	DNA-binding transcription factor activity
ICJ33_RS22065	COG4941	Belongs to the sigma-70 factor family
ICJ33_RS22075	COG3795	YCII-related domain
ICJ33_RS22095	COG0436	Aminotransferase
ICJ33_RS22105	COG3265	gluconokinase activity
ICJ33_RS22110	COG1609	Transcriptional regulator
ICJ33_RS22130	COG2271	Major facilitator Superfamily
ICJ33_RS22160	COG0242	peptide deformylase activity
ICJ33_RS22165	COG1295	ribonuclease BN
ICJ33_RS22180	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ33_RS22185	COG0318	PFAM AMP-dependent synthetase and ligase
ICJ33_RS22195	COG2030	dehydratase
ICJ33_RS22205	COG3530	Putative quorum-sensing-regulated virulence factor
ICJ33_RS22210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICJ33_RS22215	COG0800	Aldolase
ICJ33_RS22230	COG1737	Transcriptional regulator
ICJ33_RS22235	COG0676	glucose-6-phosphate 1-epimerase activity
ICJ33_RS22245	COG3842	ATPase activity
ICJ33_RS22250	COG0395	ABC-type sugar transport system, permease component
ICJ33_RS22255	COG1175	transmembrane transport
ICJ33_RS22260	COG1653	transport
ICJ33_RS22275	COG1088	dTDP-glucose 4,6-dehydratase activity
ICJ33_RS22280	COG0583	DNA-binding transcription factor activity
ICJ33_RS22295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICJ33_RS22320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ICJ33_RS22350	COG1113	amino acid transport
ICJ33_RS22375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICJ33_RS22385	COG0009	L-threonylcarbamoyladenylate synthase
ICJ33_RS22400	COG2350	Protein conserved in bacteria
ICJ33_RS22410	COG0745	RESPONSE REGULATOR receiver
ICJ33_RS22420	COG0642	Histidine kinase
ICJ33_RS22470	COG0509	glycine decarboxylation via glycine cleavage system
ICJ33_RS22475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICJ33_RS22475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICJ33_RS22480	COG1760	l-serine dehydratase
ICJ33_RS22485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ICJ33_RS22490	COG1278	Cold shock
ICJ33_RS22500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ICJ33_RS22515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICJ33_RS22520	COG0602	queuosine metabolic process
ICJ33_RS22530	COG2885	chlorophyll binding
ICJ33_RS22535	COG0823	Involved in the tonB-independent uptake of proteins
ICJ33_RS22555	COG0824	Thioesterase
ICJ33_RS22560	COG2255	four-way junction helicase activity
ICJ33_RS22565	COG0632	four-way junction helicase activity
ICJ33_RS22570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ICJ33_RS22575	COG0217	transcriptional regulatory protein
ICJ33_RS22580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICJ33_RS22595	COG0783	Belongs to the Dps family
ICJ33_RS22605	COG2900	Belongs to the SlyX family
ICJ33_RS22620	COG0668	transmembrane transport
ICJ33_RS22625	COG1666	GTP binding
ICJ33_RS22635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS22635	COG4191	Histidine kinase
ICJ33_RS22640	COG2096	Adenosyltransferase
ICJ33_RS22650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ICJ33_RS22655	COG0653	protein targeting
ICJ33_RS22665	COG0433	COG0433 Predicted ATPase
ICJ33_RS22690	COG2925	Exonuclease
ICJ33_RS22715	COG0714	Associated with various cellular activities
ICJ33_RS22735	COG0469	pyruvate kinase activity
ICJ33_RS22740	COG1024	Enoyl-CoA hydratase
ICJ33_RS22755	COG4191	Histidine kinase
ICJ33_RS22765	COG0477	Major facilitator Superfamily
ICJ33_RS22785	COG2207	Transcriptional regulator
ICJ33_RS22820	COG3712	iron ion homeostasis
ICJ33_RS22825	COG4771	TonB-dependent receptor
ICJ33_RS22835	COG2832	Protein of unknown function (DUF454)
ICJ33_RS22870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICJ33_RS22880	COG3642	lipopolysaccharide core region biosynthetic process
ICJ33_RS22890	COG0642	Histidine kinase
ICJ33_RS22900	COG0459	protein refolding
ICJ33_RS22905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICJ33_RS22910	COG3030	protein affecting phage T7 exclusion by the F plasmid
ICJ33_RS22935	COG0442	prolyl-tRNA aminoacylation
ICJ33_RS22945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICJ33_RS22980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICJ33_RS23010	COG4974	Belongs to the 'phage' integrase family
ICJ33_RS23015	COG1607	acyl-coa hydrolase
ICJ33_RS23020	COG0335	large ribosomal subunit rRNA binding
ICJ33_RS23025	COG0336	Belongs to the RNA methyltransferase TrmD family
ICJ33_RS23030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICJ33_RS23035	COG0228	four-way junction DNA binding
ICJ33_RS23040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICJ33_RS23050	COG4536	flavin adenine dinucleotide binding
ICJ33_RS23055	COG0477	Major facilitator Superfamily
ICJ33_RS23060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICJ33_RS23095	COG2188	Transcriptional regulator
ICJ33_RS23100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICJ33_RS23105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICJ33_RS23110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICJ33_RS23110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICJ33_RS23115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICJ33_RS23115	COG2190	(PTS) system
ICJ33_RS23115	COG1263	PTS System
ICJ33_RS23130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICJ33_RS23135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICJ33_RS23135	COG0047	phosphoribosylformylglycinamidine synthase activity
ICJ33_RS23140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ICJ33_RS23150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICJ33_RS23150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICJ33_RS23155	COG4580	involved in the transport of maltose and maltodextrins
ICJ33_RS23160	COG0366	Alpha amylase catalytic
ICJ33_RS23165	COG1263	PTS System
ICJ33_RS23165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICJ33_RS23170	COG2188	Transcriptional regulator
ICJ33_RS23185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICJ33_RS23185	COG0519	Catalyzes the synthesis of GMP from XMP
ICJ33_RS23205	COG0583	DNA-binding transcription factor activity
ICJ33_RS23210	COG1570	exodeoxyribonuclease VII activity
ICJ33_RS23215	COG0739	heme binding
ICJ33_RS23220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICJ33_RS23230	COG0436	Aminotransferase
ICJ33_RS23235	COG1160	GTP binding
ICJ33_RS23250	COG0124	histidyl-tRNA synthetase
ICJ33_RS23255	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ICJ33_RS23260	COG1426	Protein conserved in bacteria
ICJ33_RS23270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ICJ33_RS23275	COG0105	UTP biosynthetic process
ICJ33_RS23285	COG0633	Ferredoxin
ICJ33_RS23290	COG0443	Heat shock 70 kDa protein
ICJ33_RS23295	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICJ33_RS23300	COG0316	Belongs to the HesB IscA family
ICJ33_RS23310	COG1104	cysteine desulfurase activity
ICJ33_RS23320	COG1045	serine acetyltransferase
ICJ33_RS23335	COG3134	Outer membrane lipoprotein
ICJ33_RS23350	COG1862	Preprotein translocase
ICJ33_RS23355	COG0343	queuine tRNA-ribosyltransferase activity
ICJ33_RS23360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICJ33_RS23395	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS23425	COG4251	negative regulation of phosphorylation
ICJ33_RS23440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS23445	COG0583	DNA-binding transcription factor activity
ICJ33_RS23450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICJ33_RS23460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICJ33_RS23465	COG0109	protoheme IX farnesyltransferase activity
ICJ33_RS23475	COG1845	cytochrome c oxidase, subunit III
ICJ33_RS23480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICJ33_RS23485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICJ33_RS23490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ICJ33_RS23495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICJ33_RS23495	COG1017	nitric oxide dioxygenase activity
ICJ33_RS23500	COG3604	Transcriptional regulator
ICJ33_RS23510	COG2207	Transcriptional regulator
ICJ33_RS23510	COG3708	Transcriptional regulator
ICJ33_RS23515	COG2909	trisaccharide binding
ICJ33_RS23530	COG1028	Short-chain dehydrogenase reductase Sdr
ICJ33_RS23535	COG0596	Alpha beta hydrolase
ICJ33_RS23545	COG1346	cytolysis
ICJ33_RS23550	COG1380	Effector of murein hydrolase LrgA
ICJ33_RS23555	COG0583	DNA-binding transcription factor activity
ICJ33_RS23565	COG1366	Belongs to the anti-sigma-factor antagonist family
ICJ33_RS23575	COG0789	Transcriptional regulator
ICJ33_RS23590	COG0302	gtp cyclohydrolase
ICJ33_RS23595	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICJ33_RS23610	COG0492	ferredoxin-NADP+ reductase activity
ICJ33_RS23615	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ICJ33_RS23630	COG0386	Belongs to the glutathione peroxidase family
ICJ33_RS23635	COG3045	CreA protein
ICJ33_RS23640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICJ33_RS23645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICJ33_RS23650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ICJ33_RS23655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ICJ33_RS23660	COG0142	geranyltranstransferase activity
ICJ33_RS23665	COG2824	Alkylphosphonate utilization operon protein PhnA
ICJ33_RS23670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICJ33_RS23675	COG0545	Peptidyl-prolyl cis-trans isomerase
ICJ33_RS23680	COG0840	transmembrane signaling receptor activity
ICJ33_RS23690	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ICJ33_RS23700	COG2610	gluconate transmembrane transporter activity
ICJ33_RS23710	COG0659	secondary active sulfate transmembrane transporter activity
ICJ33_RS23720	COG0583	DNA-binding transcription factor activity
ICJ33_RS23725	COG2249	NAD(P)H dehydrogenase (quinone) activity
ICJ33_RS23740	COG1113	amino acid transport
ICJ33_RS23750	COG1522	sequence-specific DNA binding
ICJ33_RS23755	COG3485	protocatechuate 3,4-dioxygenase
ICJ33_RS23760	COG4829	muconolactone delta-isomerase
ICJ33_RS23765	COG4948	Mandelate Racemase Muconate Lactonizing
ICJ33_RS23780	COG4638	Rieske (2fe-2S)
ICJ33_RS23785	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ICJ33_RS23790	COG0543	2 iron, 2 sulfur cluster binding
ICJ33_RS23790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICJ33_RS23795	COG1113	amino acid transport
ICJ33_RS23800	COG3483	tryptophan 2,3-dioxygenase activity
ICJ33_RS23805	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ICJ33_RS23835	COG0583	DNA-binding transcription factor activity
ICJ33_RS23865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICJ33_RS23870	COG1074	ATP-dependent DNA helicase activity
ICJ33_RS23905	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ICJ33_RS23910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ICJ33_RS23915	COG1183	phosphatidylcholine synthase activity
ICJ33_RS23920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICJ33_RS23930	COG0028	Belongs to the TPP enzyme family
ICJ33_RS23935	COG3098	single-species biofilm formation
ICJ33_RS23945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICJ33_RS23965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ICJ33_RS23970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICJ33_RS23975	COG4558	Periplasmic binding protein
ICJ33_RS23985	COG1489	DNA binding
ICJ33_RS23990	COG0436	Aminotransferase
ICJ33_RS24000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICJ33_RS24010	COG4191	Histidine kinase
ICJ33_RS24030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ICJ33_RS24035	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ICJ33_RS24040	COG0166	Belongs to the GPI family
ICJ33_RS24045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICJ33_RS24055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICJ33_RS24065	COG2823	Periplasmic or secreted lipoprotein
ICJ33_RS24070	COG1185	polyribonucleotide nucleotidyltransferase activity
ICJ33_RS24075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICJ33_RS24080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICJ33_RS24085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICJ33_RS24090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICJ33_RS24095	COG0195	Participates in both transcription termination and antitermination
ICJ33_RS24100	COG0779	Required for maturation of 30S ribosomal subunits
ICJ33_RS24115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ICJ33_RS24120	COG0149	triose-phosphate isomerase activity
ICJ33_RS24125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICJ33_RS24130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICJ33_RS24140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ICJ33_RS24155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ33_RS24160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ICJ33_RS24165	COG0505	Belongs to the CarA family
ICJ33_RS24170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ICJ33_RS24175	COG0484	heat shock protein binding
ICJ33_RS24180	COG0443	Heat shock 70 kDa protein
ICJ33_RS24185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICJ33_RS24190	COG0497	DNA recombination
ICJ33_RS24195	COG0735	belongs to the Fur family
ICJ33_RS24200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICJ33_RS24205	COG2914	Belongs to the UPF0125 (RnfH) family
ICJ33_RS24215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICJ33_RS24220	COG2186	Transcriptional regulator
ICJ33_RS24225	COG1620	l-lactate permease
ICJ33_RS24245	COG0582	viral genome integration into host DNA
ICJ33_RS24265	COG4983	Phage plasmid primase, P4 family domain protein
ICJ33_RS24280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICJ33_RS24305	COG1715	Restriction endonuclease
ICJ33_RS24345	COG2862	Uncharacterized protein family, UPF0114
ICJ33_RS24385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ33_RS24395	COG0488	(ABC) transporter
ICJ33_RS24410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICJ33_RS24415	COG0523	cobalamin synthesis protein
ICJ33_RS24420	COG2879	small protein
ICJ33_RS24425	COG1966	Carbon starvation protein
ICJ33_RS24450	COG1970	mechanosensitive ion channel activity
ICJ33_RS24465	COG2813	Specifically methylates the guanine in position
ICJ33_RS24475	COG1294	oxidase, subunit
ICJ33_RS24480	COG1271	oxidase subunit
ICJ33_RS24490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ICJ33_RS24495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ICJ33_RS24500	COG2080	2 iron, 2 sulfur cluster binding
ICJ33_RS24510	COG2252	PERMEase
ICJ33_RS24515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICJ33_RS24555	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ICJ33_RS24560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICJ33_RS24565	COG1309	transcriptional regulator
ICJ33_RS24570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ICJ33_RS24570	COG1082	Xylose isomerase domain protein TIM barrel
ICJ33_RS24575	COG0477	Major facilitator Superfamily
ICJ33_RS24590	COG2321	neutral zinc metallopeptidase
ICJ33_RS24605	COG1946	Acyl-CoA thioesterase
ICJ33_RS24615	COG0123	including yeast histone deacetylase and acetoin utilization protein
ICJ33_RS24625	COG0513	Belongs to the DEAD box helicase family
ICJ33_RS24630	COG0697	spore germination
ICJ33_RS24635	COG1522	sequence-specific DNA binding
ICJ33_RS24640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICJ33_RS24640	COG1199	ATP-dependent helicase activity
ICJ33_RS24650	COG3416	Protein conserved in bacteria
ICJ33_RS24675	COG1643	Atp-dependent helicase
ICJ33_RS24685	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICJ33_RS24695	COG1522	sequence-specific DNA binding
ICJ33_RS24710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICJ33_RS24715	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS24730	COG0352	thiamine-phosphate diphosphorylase activity
ICJ33_RS24735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICJ33_RS24750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICJ33_RS24755	COG1702	phosphate starvation-inducible protein PhoH
ICJ33_RS24760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICJ33_RS24765	COG4535	Mg2 and Co2 transporter CorC
ICJ33_RS24770	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ICJ33_RS24785	COG0495	leucyl-tRNA aminoacylation
ICJ33_RS24795	COG1466	dna polymerase III delta subunit
ICJ33_RS24805	COG2951	lytic endotransglycosylase activity
ICJ33_RS24815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ICJ33_RS24820	COG0321	lipoyl(octanoyl) transferase activity
ICJ33_RS24825	COG2921	Belongs to the UPF0250 family
ICJ33_RS24830	COG1686	Belongs to the peptidase S11 family
ICJ33_RS24840	COG2951	lytic endotransglycosylase activity
ICJ33_RS24845	COG0772	Belongs to the SEDS family
ICJ33_RS24850	COG0768	penicillin binding
ICJ33_RS24855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICJ33_RS24865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICJ33_RS24870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICJ33_RS24875	COG2094	Belongs to the DNA glycosylase MPG family
ICJ33_RS24880	COG0586	Pfam SNARE associated Golgi protein
ICJ33_RS24890	COG1346	cytolysis
ICJ33_RS24895	COG1380	Effector of murein hydrolase LrgA
ICJ33_RS24910	COG0702	epimerase
ICJ33_RS24925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICJ33_RS24930	COG3284	Transcriptional regulator
ICJ33_RS24940	COG0531	amino acid
ICJ33_RS24945	COG4303	Ethanolamine ammonia lyase large subunit
ICJ33_RS24950	COG4302	ethanolamine ammonia-lyase activity
ICJ33_RS24955	COG0456	acetyltransferase
ICJ33_RS24960	COG0586	Pfam SNARE associated Golgi protein
ICJ33_RS24965	COG3228	Belongs to the MtfA family
ICJ33_RS24970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICJ33_RS24980	COG1335	isochorismatase
ICJ33_RS24995	COG1722	exodeoxyribonuclease VII activity
ICJ33_RS25000	COG0142	geranyltranstransferase activity
ICJ33_RS25005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICJ33_RS25010	COG4206	TonB-dependent receptor
ICJ33_RS25020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICJ33_RS25030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICJ33_RS25040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ICJ33_RS25045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICJ33_RS25050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ICJ33_RS25065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICJ33_RS25065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICJ33_RS25070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICJ33_RS25080	COG2264	protein methyltransferase activity
ICJ33_RS25085	COG3118	belongs to the thioredoxin family
ICJ33_RS25100	COG4181	ATPase activity
ICJ33_RS25125	COG0668	transmembrane transport
ICJ33_RS25130	COG3568	Endonuclease Exonuclease Phosphatase
ICJ33_RS25135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ33_RS25140	COG0392	lysyltransferase activity
ICJ33_RS25160	COG1335	isochorismatase
ICJ33_RS25165	COG4106	trans-aconitate 2-methyltransferase activity
ICJ33_RS25190	COG0629	single-stranded DNA binding
ICJ33_RS25195	COG2814	Major facilitator Superfamily
ICJ33_RS25200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ICJ33_RS25205	COG2193	ferroxidase activity
ICJ33_RS25215	COG0203	ribosomal protein L17
ICJ33_RS25220	COG0202	RNA polymerase activity
ICJ33_RS25225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICJ33_RS25230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICJ33_RS25235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICJ33_RS25240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ICJ33_RS25250	COG0200	Binds to the 23S rRNA
ICJ33_RS25255	COG1841	ribosomal large subunit assembly
ICJ33_RS25260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICJ33_RS25265	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICJ33_RS25270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICJ33_RS25275	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICJ33_RS25280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICJ33_RS25285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICJ33_RS25290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICJ33_RS25295	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICJ33_RS25300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICJ33_RS25305	COG0255	Belongs to the universal ribosomal protein uL29 family
ICJ33_RS25310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICJ33_RS25315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICJ33_RS25320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICJ33_RS25325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICJ33_RS25330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICJ33_RS25335	COG0089	rRNA binding
ICJ33_RS25340	COG0088	Forms part of the polypeptide exit tunnel
ICJ33_RS25345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICJ33_RS25350	COG0051	transcription antitermination factor activity, RNA binding
ICJ33_RS25355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICJ33_RS25360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICJ33_RS25365	COG0049	tRNA binding
ICJ33_RS25370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICJ33_RS25375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICJ33_RS25380	COG0085	RNA polymerase activity
ICJ33_RS25385	COG0222	ribosome binding
ICJ33_RS25390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICJ33_RS25395	COG0081	regulation of translation
ICJ33_RS25400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICJ33_RS25440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICJ33_RS25475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICJ33_RS25480	COG0739	heme binding
ICJ33_RS25485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ICJ33_RS25490	COG0316	Belongs to the HesB IscA family
ICJ33_RS25495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICJ33_RS25500	COG1981	membrane
ICJ33_RS25520	COG0537	adenosine 5'-monophosphoramidase activity
ICJ33_RS25525	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ICJ33_RS25530	COG1765	OsmC-like protein
ICJ33_RS25545	COG0134	indole-3-glycerol-phosphate synthase activity
ICJ33_RS25550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICJ33_RS25555	COG0512	Glutamine amidotransferase of anthranilate synthase
ICJ33_RS25560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICJ33_RS25565	COG0546	phosphoglycolate phosphatase activity
ICJ33_RS25570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ICJ33_RS25575	COG1454	alcohol dehydrogenase
ICJ33_RS25585	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICJ33_RS25595	COG3842	ATPase activity
ICJ33_RS25600	COG2197	response regulator
ICJ33_RS25615	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICJ33_RS25620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICJ33_RS25630	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICJ33_RS25635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICJ33_RS25640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICJ33_RS25645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ICJ33_RS25650	COG2967	ApaG domain
ICJ33_RS25655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICJ33_RS25665	COG2766	serine protein kinase
ICJ33_RS25670	COG2718	Belongs to the UPF0229 family
ICJ33_RS25675	COG2719	SpoVR family
ICJ33_RS25680	COG0617	tRNA 3'-terminal CCA addition
ICJ33_RS25690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICJ33_RS25695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ICJ33_RS25700	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICJ33_RS25705	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ICJ33_RS25710	COG0358	DNA primase activity
ICJ33_RS25715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICJ33_RS25735	COG0583	DNA-binding transcription factor activity
ICJ33_RS25750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICJ33_RS25755	COG1025	Belongs to the peptidase M16 family
ICJ33_RS25765	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ICJ33_RS25770	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ICJ33_RS25780	COG0535	radical SAM domain protein
ICJ33_RS25790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICJ33_RS25795	COG0583	DNA-binding transcription factor activity
ICJ33_RS25800	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS25805	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS25815	COG1960	acyl-CoA dehydrogenase activity
ICJ33_RS25835	COG2226	methyltransferase
ICJ33_RS25835	COG1073	alpha beta
ICJ33_RS25840	COG0156	8-amino-7-oxononanoate synthase activity
ICJ33_RS25845	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICJ33_RS25850	COG1040	competence protein
ICJ33_RS25855	COG2005	Transcriptional regulator
ICJ33_RS25855	COG3585	molybdate ion transport
ICJ33_RS25865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ICJ33_RS25880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ICJ33_RS25890	COG3279	Response regulator of the LytR AlgR family
ICJ33_RS25905	COG1595	DNA-templated transcription, initiation
ICJ33_RS25920	COG4774	siderophore transport
ICJ33_RS25935	COG2423	ornithine cyclodeaminase activity
ICJ33_RS25940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS25955	COG1126	abc transporter atp-binding protein
ICJ33_RS25960	COG2964	Protein conserved in bacteria
ICJ33_RS25970	COG4452	Inner membrane protein CreD
ICJ33_RS25975	COG2205	protein histidine kinase activity
ICJ33_RS25985	COG0189	ligase activity
ICJ33_RS25985	COG4067	protein conserved in archaea
ICJ33_RS25990	COG0204	Acyl-transferase
ICJ33_RS26005	COG1063	alcohol dehydrogenase
ICJ33_RS26035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICJ33_RS26055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICJ33_RS26055	COG1017	nitric oxide dioxygenase activity
ICJ33_RS26060	COG4638	Rieske (2fe-2S)
ICJ33_RS26070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ICJ33_RS26075	COG0247	lactate metabolic process
ICJ33_RS26075	COG2181	nitrate reductase activity
ICJ33_RS26080	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICJ33_RS26080	COG1902	pentaerythritol trinitrate reductase activity
ICJ33_RS26120	COG3246	L-lysine catabolic process to acetate
ICJ33_RS26125	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICJ33_RS26150	COG1760	l-serine dehydratase
ICJ33_RS26160	COG4176	ABC-type proline glycine betaine transport system permease component
ICJ33_RS26165	COG4175	Glycine betaine
ICJ33_RS26170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ICJ33_RS26175	COG1309	transcriptional regulator
ICJ33_RS26180	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS26185	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ICJ33_RS26205	COG0477	Major facilitator Superfamily
ICJ33_RS26210	COG0513	Belongs to the DEAD box helicase family
ICJ33_RS26215	COG2081	HI0933 family
ICJ33_RS26220	COG1289	transmembrane transporter activity
ICJ33_RS26230	COG2153	protein acetylation
ICJ33_RS26240	COG1451	nucleotide metabolic process
ICJ33_RS26270	COG0126	phosphoglycerate kinase activity
ICJ33_RS26275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICJ33_RS26280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICJ33_RS26285	COG0640	Transcriptional regulator
ICJ33_RS26290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICJ33_RS26300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICJ33_RS26330	COG2116	formate transmembrane transporter activity
ICJ33_RS26345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ICJ33_RS26350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ICJ33_RS26365	COG0513	Belongs to the DEAD box helicase family
ICJ33_RS26370	COG2353	YceI-like domain
ICJ33_RS26375	COG3038	cytochrome b561
ICJ33_RS26385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ICJ33_RS26410	COG1272	protein, Hemolysin III
ICJ33_RS26430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ICJ33_RS26450	COG3052	prosthetic group binding
ICJ33_RS26455	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ICJ33_RS26480	COG3093	addiction module antidote protein HigA
ICJ33_RS26490	COG0643	Histidine kinase
ICJ33_RS26490	COG2198	Histidine kinase
ICJ33_RS26490	COG0784	Response regulator, receiver
ICJ33_RS26515	COG0189	ligase activity
ICJ33_RS26525	COG1678	Uncharacterized ACR, COG1678
ICJ33_RS26530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICJ33_RS26535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICJ33_RS26540	COG0540	Belongs to the ATCase OTCase family
ICJ33_RS26545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICJ33_RS26555	COG0791	NLP P60 protein
ICJ33_RS26580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ33_RS26585	COG2813	Specifically methylates the guanine in position
ICJ33_RS26585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICJ33_RS26595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICJ33_RS26600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICJ33_RS26610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ICJ33_RS26615	COG2022	thiamine diphosphate biosynthetic process
ICJ33_RS26625	COG2363	Small membrane protein
ICJ33_RS26630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICJ33_RS26640	COG2177	Part of the ABC transporter FtsEX involved in
ICJ33_RS26645	COG2884	Cell division ATP-binding protein ftsE
ICJ33_RS26650	COG0552	protein localization to endoplasmic reticulum
ICJ33_RS26655	COG0612	Peptidase, M16
ICJ33_RS26660	COG0612	Peptidase, M16
ICJ33_RS26665	COG0742	ribosomal rna small subunit methyltransferase
ICJ33_RS26670	COG0429	hydrolase of the alpha beta-hydrolase fold
ICJ33_RS26680	COG1309	transcriptional regulator
ICJ33_RS26695	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ICJ33_RS26700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICJ33_RS26705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICJ33_RS26710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ICJ33_RS26720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICJ33_RS26725	COG2814	Major facilitator Superfamily
ICJ33_RS26730	COG0129	dihydroxy-acid dehydratase activity
ICJ33_RS26740	COG1823	symporter activity
ICJ33_RS26755	COG1160	GTP binding
ICJ33_RS26775	COG1840	ABC-type Fe3 transport system, periplasmic component
ICJ33_RS26780	COG1178	ABC-type Fe3 transport system permease component
ICJ33_RS26785	COG3842	ATPase activity
ICJ33_RS26790	COG0583	DNA-binding transcription factor activity
ICJ33_RS26800	COG0789	Transcriptional regulator
ICJ33_RS26805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICJ33_RS26810	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICJ33_RS26815	COG0730	response to heat
ICJ33_RS26830	COG0494	nUDIX hydrolase
ICJ33_RS26850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICJ33_RS26855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICJ33_RS26860	COG3204	pilus organization
ICJ33_RS26865	COG3204	pilus organization
ICJ33_RS26870	COG0179	Fumarylacetoacetate (FAA) hydrolase
ICJ33_RS26875	COG0277	FAD linked oxidase domain protein
ICJ33_RS26880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICJ33_RS26890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS26895	COG1683	Conserved Protein
ICJ33_RS26925	COG1917	Cupin 2, conserved barrel domain protein
ICJ33_RS26925	COG4977	sequence-specific DNA binding
ICJ33_RS26930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICJ33_RS26945	COG1177	transmembrane transport
ICJ33_RS26950	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICJ33_RS26955	COG3842	ATPase activity
ICJ33_RS26975	COG0174	glutamine synthetase
ICJ33_RS26980	COG0174	glutamine synthetase
ICJ33_RS26995	COG1116	anion transmembrane transporter activity
ICJ33_RS27000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICJ33_RS27005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICJ33_RS27010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICJ33_RS27015	COG0431	NADPH-dependent FMN reductase
ICJ33_RS27025	COG0450	alkyl hydroperoxide reductase
ICJ33_RS27035	COG4521	taurine ABC transporter
ICJ33_RS27040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ICJ33_RS27040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICJ33_RS27055	COG1522	sequence-specific DNA binding
ICJ33_RS27065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICJ33_RS27070	COG0330	HflC and HflK could
ICJ33_RS27090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICJ33_RS27095	COG0509	glycine decarboxylation via glycine cleavage system
ICJ33_RS27100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ICJ33_RS27105	COG1178	ABC-type Fe3 transport system permease component
ICJ33_RS27115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICJ33_RS27125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICJ33_RS27130	COG0006	proline dipeptidase activity
ICJ33_RS27135	COG3079	Belongs to the UPF0149 family
ICJ33_RS27155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICJ33_RS27170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICJ33_RS27175	COG0842	Transport permease protein
ICJ33_RS27175	COG1129	ABC transporter
ICJ33_RS27180	COG0842	Transport permease protein
ICJ33_RS27195	COG2271	Major facilitator Superfamily
ICJ33_RS27215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ICJ33_RS27230	COG2186	Transcriptional regulator
ICJ33_RS27235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS27240	COG0765	amino acid transport
ICJ33_RS27245	COG0765	amino acid transport
ICJ33_RS27250	COG1126	abc transporter atp-binding protein
ICJ33_RS27260	COG3188	usher protein
ICJ33_RS27265	COG3121	Chaperone
ICJ33_RS27275	COG0248	Ppx GppA phosphatase
ICJ33_RS27285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICJ33_RS27295	COG0586	Pfam SNARE associated Golgi protein
ICJ33_RS27305	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ICJ33_RS27310	COG1671	Belongs to the UPF0178 family
ICJ33_RS27315	COG0672	)-iron permease
ICJ33_RS27330	COG0488	(ABC) transporter
ICJ33_RS27355	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ICJ33_RS27370	COG0181	hydroxymethylbilane synthase activity
ICJ33_RS27380	COG0165	Argininosuccinate lyase
ICJ33_RS27385	COG0625	glutathione transferase activity
ICJ33_RS27405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICJ33_RS27415	COG1965	Belongs to the frataxin family
ICJ33_RS27425	COG0019	diaminopimelate decarboxylase activity
ICJ33_RS27430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICJ33_RS27440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ICJ33_RS27445	COG1011	Hydrolase
ICJ33_RS27455	COG0432	Pfam Uncharacterised protein family UPF0047
ICJ33_RS27460	COG0004	ammonium transporteR
ICJ33_RS27465	COG0347	Belongs to the P(II) protein family
ICJ33_RS27480	COG0606	chelatase, subunit chli
ICJ33_RS27495	COG0840	transmembrane signaling receptor activity
ICJ33_RS27500	COG0583	DNA-binding transcription factor activity
ICJ33_RS27505	COG0534	Mate efflux family protein
ICJ33_RS27520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICJ33_RS27525	COG0427	acetyl-CoA hydrolase
ICJ33_RS27540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICJ33_RS27545	COG0251	oxidation-reduction process
ICJ33_RS27550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS27565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICJ33_RS27575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICJ33_RS27580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ33_RS27590	COG1012	belongs to the aldehyde dehydrogenase family
ICJ33_RS27600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ICJ33_RS27605	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ICJ33_RS27610	COG0747	negative chemotaxis
ICJ33_RS27615	COG2003	Belongs to the UPF0758 family
ICJ33_RS27620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICJ33_RS27625	COG0756	dUTP diphosphatase activity
ICJ33_RS27630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICJ33_RS27635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICJ33_RS27640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICJ33_RS27645	COG0708	Exodeoxyribonuclease III
ICJ33_RS27655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICJ33_RS27660	COG1561	YicC-like family, N-terminal region
ICJ33_RS27670	COG1758	RNA polymerase activity
ICJ33_RS27675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICJ33_RS27700	COG0848	biopolymer transport protein
ICJ33_RS27710	COG0583	DNA-binding transcription factor activity
ICJ33_RS27715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICJ33_RS27745	COG1136	(ABC) transporter
ICJ33_RS27750	COG0515	serine threonine protein kinase
ICJ33_RS27750	COG2815	serine threonine protein kinase
ICJ33_RS27755	COG0631	protein serine/threonine phosphatase activity
ICJ33_RS27865	COG3161	chorismate lyase activity
ICJ33_RS27870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ICJ33_RS27890	COG1253	flavin adenine dinucleotide binding
ICJ33_RS27895	COG0739	heme binding
ICJ33_RS27905	COG0704	Plays a role in the regulation of phosphate uptake
ICJ33_RS27910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ICJ33_RS27915	COG0573	inorganic phosphate transmembrane transporter activity
ICJ33_RS27930	COG0477	Major facilitator Superfamily
ICJ33_RS27935	COG1607	acyl-coa hydrolase
ICJ33_RS27965	COG0583	DNA-binding transcription factor activity
ICJ33_RS27970	COG1027	Aspartate ammonia-lyase
ICJ33_RS27975	COG1115	amino acid carrier protein
ICJ33_RS27980	COG0252	asparaginase activity
ICJ33_RS28010	COG2808	Putative FMN-binding domain
ICJ33_RS28030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICJ33_RS28035	COG0765	amino acid transport
ICJ33_RS28050	COG5016	pyruvate
ICJ33_RS28050	COG0511	ligase activity, forming carbon-carbon bonds
ICJ33_RS28055	COG0439	Biotin carboxylase
ICJ33_RS28060	COG0583	DNA-binding transcription factor activity
ICJ33_RS28070	COG3300	MHYT domain
ICJ33_RS28070	COG5001	Diguanylate cyclase
ICJ33_RS28075	COG0210	DNA helicase
ICJ33_RS28090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICJ33_RS28090	COG4651	solute:proton antiporter activity
ICJ33_RS28095	COG1607	acyl-coa hydrolase
ICJ33_RS28100	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ICJ33_RS28110	COG0523	cobalamin synthesis protein
ICJ33_RS28135	COG0860	N-Acetylmuramoyl-L-alanine amidase
ICJ33_RS28140	COG1469	GTP cyclohydrolase I activity
ICJ33_RS28145	COG1121	(ABC) transporter
ICJ33_RS28160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICJ33_RS28170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICJ33_RS28180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICJ33_RS28185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICJ33_RS28195	COG3220	belongs to the UPF0276 family
ICJ33_RS28225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICJ33_RS28230	COG2267	carboxylic ester hydrolase activity
ICJ33_RS28235	COG0671	phosphoesterase, PA-phosphatase related
ICJ33_RS28235	COG2453	phosphatase
ICJ33_RS28250	COG4589	Belongs to the CDS family
ICJ33_RS28255	COG1522	sequence-specific DNA binding
ICJ33_RS28260	COG1280	lysine exporter protein (LysE YggA)
ICJ33_RS28265	COG2373	Large extracellular alpha-helical protein
ICJ33_RS28270	COG4953	penicillin-binding protein 1C
ICJ33_RS28280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICJ33_RS28285	COG1349	DNA-binding transcription factor activity
ICJ33_RS28290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICJ33_RS28295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ICJ33_RS28300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICJ33_RS28305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICJ33_RS28310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICJ33_RS28315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICJ33_RS28320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICJ33_RS28330	COG0356	it plays a direct role in the translocation of protons across the membrane
ICJ33_RS28335	COG3312	ion transport
ICJ33_RS28340	COG1475	DNA binding
ICJ33_RS28345	COG1192	Involved in chromosome partitioning
ICJ33_RS28350	COG0357	Ribosomal RNA small subunit methyltransferase G
ICJ33_RS28355	COG0445	tRNA wobble uridine modification
ICJ33_RS28360	COG1595	DNA-templated transcription, initiation
ICJ33_RS28365	COG3712	iron ion homeostasis
ICJ33_RS28375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICJ33_RS28380	COG0706	membrane insertase activity
ICJ33_RS28385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ICJ33_RS28390	COG0594	ribonuclease P activity
ICJ33_RS28395	COG0230	Belongs to the bacterial ribosomal protein bL34 family