locus-tag	class	description
PMA3_RS00020	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PMA3_RS00025	COG0735	belongs to the Fur family
PMA3_RS00030	COG1121	(ABC) transporter
PMA3_RS00035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PMA3_RS00050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMA3_RS00055	COG2011	ABC-type metal ion transport system permease component
PMA3_RS00070	COG0109	protoheme IX farnesyltransferase activity
PMA3_RS00085	COG3346	SURF1 family
PMA3_RS00100	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PMA3_RS00105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PMA3_RS00110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PMA3_RS00120	COG0659	secondary active sulfate transmembrane transporter activity
PMA3_RS00140	COG0339	signal peptide processing
PMA3_RS00145	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
PMA3_RS00150	COG0339	signal peptide processing
PMA3_RS00155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PMA3_RS00185	COG1764	response to oxidative stress
PMA3_RS00190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PMA3_RS00220	COG0159	tryptophan synthase activity
PMA3_RS00250	COG0427	acetyl-CoA hydrolase
PMA3_RS00270	COG0583	DNA-binding transcription factor activity
PMA3_RS00275	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS00300	COG3712	iron ion homeostasis
PMA3_RS00310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PMA3_RS00325	COG1802	Transcriptional regulator
PMA3_RS00340	COG0457	Tetratricopeptide repeat
PMA3_RS00340	COG3118	belongs to the thioredoxin family
PMA3_RS00345	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PMA3_RS00350	COG1215	transferase activity, transferring glycosyl groups
PMA3_RS00355	COG1215	transferase activity, transferring glycosyl groups
PMA3_RS00370	COG2194	sulfuric ester hydrolase activity
PMA3_RS00385	COG2175	clavaminate synthase activity
PMA3_RS00400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMA3_RS00405	COG0330	HflC and HflK could
PMA3_RS00435	COG1289	transmembrane transporter activity
PMA3_RS00460	COG5339	Protein conserved in bacteria
PMA3_RS00465	COG0457	Tetratricopeptide repeat
PMA3_RS00470	COG1649	PFAM Uncharacterised BCR, COG1649
PMA3_RS00470	COG0726	polysaccharide deacetylase
PMA3_RS00475	COG1215	transferase activity, transferring glycosyl groups
PMA3_RS00485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMA3_RS00495	COG2304	oxidoreductase activity
PMA3_RS00500	COG1595	DNA-templated transcription, initiation
PMA3_RS00520	COG0745	RESPONSE REGULATOR receiver
PMA3_RS00525	COG3706	GGDEF domain
PMA3_RS00535	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS00540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PMA3_RS00545	COG0745	RESPONSE REGULATOR receiver
PMA3_RS00550	COG2199	diguanylate cyclase activity
PMA3_RS00570	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PMA3_RS00580	COG4208	sulfate ABC transporter
PMA3_RS00585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PMA3_RS00595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMA3_RS00615	COG3829	transcription factor binding
PMA3_RS00630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMA3_RS00635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS00665	COG0667	Aldo Keto reductase
PMA3_RS00670	COG3424	synthase
PMA3_RS00675	COG2011	ABC-type metal ion transport system permease component
PMA3_RS00680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMA3_RS00685	COG1464	Belongs to the NlpA lipoprotein family
PMA3_RS00710	COG1126	abc transporter atp-binding protein
PMA3_RS00715	COG0765	amino acid transport
PMA3_RS00720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS00730	COG1045	serine acetyltransferase
PMA3_RS00735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PMA3_RS00750	COG0667	Aldo Keto reductase
PMA3_RS00755	COG2175	clavaminate synthase activity
PMA3_RS00760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMA3_RS00765	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PMA3_RS00770	COG4521	taurine ABC transporter
PMA3_RS00775	COG2918	glutathione biosynthetic process
PMA3_RS00790	COG2183	response to ionizing radiation
PMA3_RS00805	COG0189	ligase activity
PMA3_RS00810	COG0189	ligase activity
PMA3_RS00810	COG4067	protein conserved in archaea
PMA3_RS00815	COG2200	EAL domain
PMA3_RS00815	COG2199	diguanylate cyclase activity
PMA3_RS00815	COG3287	FIST C domain
PMA3_RS00820	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PMA3_RS00825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PMA3_RS00830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PMA3_RS00855	COG0514	ATP-dependent DNA helicase (RecQ)
PMA3_RS00870	COG0243	molybdopterin cofactor binding
PMA3_RS00875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PMA3_RS00880	COG0583	DNA-binding transcription factor activity
PMA3_RS00885	COG1652	LysM domain
PMA3_RS00890	COG1011	Hydrolase
PMA3_RS00895	COG0494	nUDIX hydrolase
PMA3_RS00900	COG1218	3'(2'),5'-bisphosphate nucleotidase
PMA3_RS00920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PMA3_RS00930	COG2957	Belongs to the agmatine deiminase family
PMA3_RS00945	COG3177	Filamentation induced by cAMP protein fic
PMA3_RS00965	COG1942	4-Oxalocrotonate Tautomerase
PMA3_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS01000	COG4215	(ABC) transporter
PMA3_RS01035	COG4804	nuclease activity
PMA3_RS01060	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PMA3_RS01065	COG1194	a g-specific adenine glycosylase
PMA3_RS01075	COG0131	Imidazoleglycerol-phosphate dehydratase
PMA3_RS01080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PMA3_RS01090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PMA3_RS01095	COG0107	imidazoleglycerol-phosphate synthase activity
PMA3_RS01115	COG2861	carbohydrate metabolic process
PMA3_RS01120	COG0793	Belongs to the peptidase S41A family
PMA3_RS01125	COG4942	peptidase
PMA3_RS01130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMA3_RS01145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PMA3_RS01170	COG3852	Histidine kinase
PMA3_RS01190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMA3_RS01190	COG0301	tRNA thio-modification
PMA3_RS01195	COG1217	gtp-binding protein TYPA
PMA3_RS01210	COG0058	SHG alpha-glucan phosphorylase activity
PMA3_RS01225	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PMA3_RS01245	COG3040	lipid binding
PMA3_RS01250	COG0402	S-adenosylhomocysteine deaminase activity
PMA3_RS01255	COG2188	Transcriptional regulator
PMA3_RS01265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PMA3_RS01270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PMA3_RS01280	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS01285	COG4175	Glycine betaine
PMA3_RS01285	COG0517	IMP dehydrogenase activity
PMA3_RS01290	COG2986	histidine ammonia-lyase
PMA3_RS01295	COG2986	histidine ammonia-lyase
PMA3_RS01300	COG1228	amidohydrolase
PMA3_RS01310	COG0596	Alpha beta hydrolase
PMA3_RS01315	COG1490	D-aminoacyl-tRNA deacylase activity
PMA3_RS01320	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PMA3_RS01325	COG2943	transferase activity, transferring hexosyl groups
PMA3_RS01335	COG0765	amino acid transport
PMA3_RS01340	COG1126	abc transporter atp-binding protein
PMA3_RS01345	COG0840	transmembrane signaling receptor activity
PMA3_RS01360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PMA3_RS01365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PMA3_RS01370	COG0140	phosphoribosyl-ATP diphosphatase activity
PMA3_RS01375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PMA3_RS01380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PMA3_RS01390	COG2226	methyltransferase
PMA3_RS01410	COG1309	transcriptional regulator
PMA3_RS01435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PMA3_RS01440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PMA3_RS01450	COG0018	arginyl-trna synthetase
PMA3_RS01455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMA3_RS01460	COG0254	rRNA binding
PMA3_RS01470	COG0281	malic enzyme
PMA3_RS01475	COG3547	Transposase (IS116 IS110 IS902 family)
PMA3_RS01510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PMA3_RS01515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PMA3_RS01525	COG0069	glutamate synthase activity
PMA3_RS01525	COG0070	glutamate synthase
PMA3_RS01525	COG0067	glutamate synthase
PMA3_RS01530	COG0493	'glutamate synthase
PMA3_RS01535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PMA3_RS01540	COG2814	Major facilitator Superfamily
PMA3_RS01545	COG0583	DNA-binding transcription factor activity
PMA3_RS01555	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PMA3_RS01580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PMA3_RS01590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PMA3_RS01595	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS01605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PMA3_RS01640	COG2986	histidine ammonia-lyase
PMA3_RS01665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMA3_RS01670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMA3_RS01685	COG1192	Involved in chromosome partitioning
PMA3_RS01690	COG3118	belongs to the thioredoxin family
PMA3_RS01695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PMA3_RS01700	COG3264	Mechanosensitive ion channel
PMA3_RS01700	COG1196	nuclear chromosome segregation
PMA3_RS01705	COG3263	regulation of cellular component size
PMA3_RS01720	COG0840	transmembrane signaling receptor activity
PMA3_RS01725	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS01730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PMA3_RS01730	COG0506	proline dehydrogenase activity
PMA3_RS01730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PMA3_RS01735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMA3_RS01740	COG3209	COG3209 Rhs family protein
PMA3_RS01745	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PMA3_RS01750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMA3_RS01775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PMA3_RS01780	COG0859	PFAM glycosyl transferase family 9
PMA3_RS01790	COG0438	transferase activity, transferring glycosyl groups
PMA3_RS01820	COG2192	nodulation
PMA3_RS01825	COG0438	transferase activity, transferring glycosyl groups
PMA3_RS01850	COG0438	transferase activity, transferring glycosyl groups
PMA3_RS01865	COG1132	(ABC) transporter
PMA3_RS01870	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PMA3_RS01870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PMA3_RS01880	COG0667	Aldo Keto reductase
PMA3_RS01900	COG1519	Transferase
PMA3_RS01905	COG1538	Outer membrane efflux protein
PMA3_RS01910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PMA3_RS01925	COG0494	nUDIX hydrolase
PMA3_RS01935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PMA3_RS01940	COG3150	esterase
PMA3_RS01955	COG3577	Aspartyl protease
PMA3_RS01975	COG0560	Phosphoserine phosphatase
PMA3_RS01975	COG3830	Belongs to the UPF0237 family
PMA3_RS01990	COG0688	phosphatidylethanolamine metabolic process
PMA3_RS02015	COG1162	GTPase activity
PMA3_RS02020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PMA3_RS02025	COG2860	membrane
PMA3_RS02035	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PMA3_RS02035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PMA3_RS02040	COG0802	atpase or kinase
PMA3_RS02045	COG0860	N-Acetylmuramoyl-L-alanine amidase
PMA3_RS02050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PMA3_RS02055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PMA3_RS02060	COG1923	regulation of RNA biosynthetic process
PMA3_RS02065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PMA3_RS02070	COG0330	HflC and HflK could
PMA3_RS02075	COG0330	HflC and HflK could
PMA3_RS02080	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PMA3_RS02085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PMA3_RS02090	COG0840	transmembrane signaling receptor activity
PMA3_RS02095	COG1178	ABC-type Fe3 transport system permease component
PMA3_RS02115	COG0557	exoribonuclease II activity
PMA3_RS02120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMA3_RS02125	COG0360	Binds together with S18 to 16S ribosomal RNA
PMA3_RS02130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PMA3_RS02140	COG0359	binds to the 23S rRNA
PMA3_RS02145	COG0305	Participates in initiation and elongation during chromosome replication
PMA3_RS02165	COG1032	radical SAM domain protein
PMA3_RS02175	COG2308	Evidence 4 Homologs of previously reported genes of
PMA3_RS02175	COG2307	Protein conserved in bacteria
PMA3_RS02205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PMA3_RS02210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMA3_RS02215	COG0583	DNA-binding transcription factor activity
PMA3_RS02220	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS02225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS02260	COG4221	oxidoreductase activity
PMA3_RS02275	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PMA3_RS02280	COG0830	nickel cation binding
PMA3_RS02285	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PMA3_RS02300	COG2982	Protein involved in outer membrane biogenesis
PMA3_RS02330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PMA3_RS02335	COG0697	spore germination
PMA3_RS02355	COG0443	Heat shock 70 kDa protein
PMA3_RS02360	COG0484	heat shock protein binding
PMA3_RS02365	COG0789	Transcriptional regulator
PMA3_RS02380	COG4886	Leucine-rich repeat (LRR) protein
PMA3_RS02385	COG0804	urea catabolic process
PMA3_RS02390	COG0832	Belongs to the urease beta subunit family
PMA3_RS02405	COG0831	urea catabolic process
PMA3_RS02410	COG0829	nickel cation binding
PMA3_RS02420	COG0411	ABC transporter
PMA3_RS02435	COG0683	leucine binding
PMA3_RS02480	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PMA3_RS02495	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMA3_RS02520	COG2095	MarC family integral membrane protein
PMA3_RS02530	COG0151	Belongs to the GarS family
PMA3_RS02535	COG0138	bifunctional purine biosynthesis protein purh
PMA3_RS02545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMA3_RS02555	COG2264	protein methyltransferase activity
PMA3_RS02600	COG0023	Translation Initiation Factor
PMA3_RS02605	COG1166	arginine decarboxylase activity
PMA3_RS02620	COG0534	Mate efflux family protein
PMA3_RS02635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PMA3_RS02650	COG2030	dehydratase
PMA3_RS02655	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS02665	COG2207	Transcriptional regulator
PMA3_RS02680	COG0495	leucyl-tRNA aminoacylation
PMA3_RS02690	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PMA3_RS02695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PMA3_RS02700	COG4535	Mg2 and Co2 transporter CorC
PMA3_RS02705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PMA3_RS02710	COG1702	phosphate starvation-inducible protein PhoH
PMA3_RS02715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PMA3_RS02730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PMA3_RS02735	COG0352	thiamine-phosphate diphosphorylase activity
PMA3_RS02740	COG0351	phosphomethylpyrimidine kinase
PMA3_RS02745	COG2205	protein histidine kinase activity
PMA3_RS02745	COG2198	Histidine kinase
PMA3_RS02745	COG0784	Response regulator, receiver
PMA3_RS02750	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS02755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PMA3_RS02770	COG1522	sequence-specific DNA binding
PMA3_RS02790	COG1643	Atp-dependent helicase
PMA3_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS02830	COG1113	amino acid transport
PMA3_RS02840	COG2072	flavoprotein involved in K transport
PMA3_RS02860	COG3416	Protein conserved in bacteria
PMA3_RS02870	COG1199	ATP-dependent helicase activity
PMA3_RS02870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PMA3_RS02880	COG1522	sequence-specific DNA binding
PMA3_RS02885	COG0697	spore germination
PMA3_RS02890	COG0513	Belongs to the DEAD box helicase family
PMA3_RS02900	COG0123	including yeast histone deacetylase and acetoin utilization protein
PMA3_RS02910	COG1946	Acyl-CoA thioesterase
PMA3_RS02925	COG2321	neutral zinc metallopeptidase
PMA3_RS02930	COG2321	neutral zinc metallopeptidase
PMA3_RS02940	COG0697	spore germination
PMA3_RS02945	COG0477	Major facilitator Superfamily
PMA3_RS02950	COG1082	Xylose isomerase domain protein TIM barrel
PMA3_RS02950	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PMA3_RS02955	COG1309	transcriptional regulator
PMA3_RS02960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMA3_RS02965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PMA3_RS02985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMA3_RS02990	COG2252	PERMEase
PMA3_RS03000	COG0693	protein deglycase activity
PMA3_RS03015	COG1271	oxidase subunit
PMA3_RS03020	COG1294	oxidase, subunit
PMA3_RS03030	COG2813	Specifically methylates the guanine in position
PMA3_RS03045	COG1970	mechanosensitive ion channel activity
PMA3_RS03060	COG1966	Carbon starvation protein
PMA3_RS03065	COG2879	small protein
PMA3_RS03070	COG0523	cobalamin synthesis protein
PMA3_RS03080	COG2186	Transcriptional regulator
PMA3_RS03090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PMA3_RS03100	COG0488	(ABC) transporter
PMA3_RS03110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PMA3_RS03130	COG1067	ATP-dependent peptidase activity
PMA3_RS03145	COG2862	Uncharacterized protein family, UPF0114
PMA3_RS03155	COG0545	Peptidyl-prolyl cis-trans isomerase
PMA3_RS03160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PMA3_RS03165	COG2824	Alkylphosphonate utilization operon protein PhnA
PMA3_RS03170	COG0142	geranyltranstransferase activity
PMA3_RS03175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PMA3_RS03180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PMA3_RS03185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PMA3_RS03190	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PMA3_RS03195	COG3045	CreA protein
PMA3_RS03200	COG0268	Binds directly to 16S ribosomal RNA
PMA3_RS03210	COG0196	riboflavin kinase activity
PMA3_RS03215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PMA3_RS03220	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PMA3_RS03225	COG1047	Peptidyl-prolyl cis-trans
PMA3_RS03230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PMA3_RS03240	COG4969	Belongs to the N-Me-Phe pilin family
PMA3_RS03270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS03305	COG0542	response to heat
PMA3_RS03335	COG1252	NADH dehydrogenase
PMA3_RS03355	COG2814	Major facilitator Superfamily
PMA3_RS03360	COG3135	benzoate transporter
PMA3_RS03390	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PMA3_RS03395	COG0237	dephospho-CoA kinase activity
PMA3_RS03400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PMA3_RS03420	COG2823	Periplasmic or secreted lipoprotein
PMA3_RS03435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PMA3_RS03450	COG0166	Belongs to the GPI family
PMA3_RS03455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PMA3_RS03460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PMA3_RS03480	COG4191	Histidine kinase
PMA3_RS03485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMA3_RS03490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PMA3_RS03495	COG0436	Aminotransferase
PMA3_RS03500	COG1489	DNA binding
PMA3_RS03510	COG4558	Periplasmic binding protein
PMA3_RS03515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMA3_RS03520	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PMA3_RS03535	COG3501	Rhs element vgr protein
PMA3_RS03535	COG3409	Peptidoglycan-binding domain 1 protein
PMA3_RS03560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PMA3_RS03580	COG0028	Belongs to the TPP enzyme family
PMA3_RS03590	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PMA3_RS03595	COG1183	phosphatidylcholine synthase activity
PMA3_RS03600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PMA3_RS03605	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PMA3_RS03635	COG2995	paraquat-inducible protein a
PMA3_RS03640	COG2995	paraquat-inducible protein a
PMA3_RS03645	COG3008	intermembrane lipid transfer
PMA3_RS03670	COG0456	acetyltransferase
PMA3_RS03680	COG0288	reversible hydration of carbon dioxide
PMA3_RS03695	COG2031	fatty acid transporter
PMA3_RS03700	COG0477	Major facilitator Superfamily
PMA3_RS03705	COG1181	Belongs to the D-alanine--D-alanine ligase family
PMA3_RS03710	COG0405	Gamma-glutamyltransferase
PMA3_RS03720	COG2223	nitrite transmembrane transporter activity
PMA3_RS03730	COG0193	aminoacyl-tRNA hydrolase activity
PMA3_RS03735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PMA3_RS03740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMA3_RS03750	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PMA3_RS03755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PMA3_RS03765	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PMA3_RS03770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PMA3_RS03780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PMA3_RS03785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PMA3_RS03800	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PMA3_RS03810	COG0415	Belongs to the DNA photolyase family
PMA3_RS03815	COG0789	Transcriptional regulator
PMA3_RS03820	COG3272	Protein of unknown function (DUF1722)
PMA3_RS03825	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PMA3_RS03830	COG1090	epimerase
PMA3_RS03845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PMA3_RS03850	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PMA3_RS03905	COG2135	peptidase activity
PMA3_RS03910	COG0501	Belongs to the peptidase M48B family
PMA3_RS03915	COG2119	membrane
PMA3_RS03920	COG2813	Specifically methylates the guanine in position
PMA3_RS03925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMA3_RS03930	COG1280	lysine exporter protein (LysE YggA)
PMA3_RS03935	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS03950	COG2909	trisaccharide binding
PMA3_RS03960	COG4245	von Willebrand factor, type A
PMA3_RS03970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PMA3_RS03990	COG0180	Tryptophanyl-tRNA synthetase
PMA3_RS03995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PMA3_RS04000	COG0252	asparaginase activity
PMA3_RS04025	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS04030	COG0667	Aldo Keto reductase
PMA3_RS04035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PMA3_RS04040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PMA3_RS04045	COG0723	plastoquinol--plastocyanin reductase activity
PMA3_RS04050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PMA3_RS04055	COG2857	Cytochrome c1
PMA3_RS04060	COG0625	glutathione transferase activity
PMA3_RS04065	COG2969	positive regulation of protein catabolic process
PMA3_RS04070	COG2823	Periplasmic or secreted lipoprotein
PMA3_RS04075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PMA3_RS04100	COG2001	Belongs to the MraZ family
PMA3_RS04105	COG0275	rRNA processing
PMA3_RS04120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMA3_RS04125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PMA3_RS04130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PMA3_RS04135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PMA3_RS04140	COG0772	Belongs to the SEDS family
PMA3_RS04145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMA3_RS04150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PMA3_RS04155	COG1181	Belongs to the D-alanine--D-alanine ligase family
PMA3_RS04170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMA3_RS04175	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PMA3_RS04180	COG4251	negative regulation of phosphorylation
PMA3_RS04180	COG5001	Diguanylate cyclase
PMA3_RS04180	COG3706	GGDEF domain
PMA3_RS04180	COG2203	Gaf domain
PMA3_RS04190	COG5002	protein histidine kinase activity
PMA3_RS04235	COG3604	Transcriptional regulator
PMA3_RS04240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PMA3_RS04240	COG1017	nitric oxide dioxygenase activity
PMA3_RS04260	COG0513	Belongs to the DEAD box helicase family
PMA3_RS04265	COG0400	carboxylic ester hydrolase activity
PMA3_RS04270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS04275	COG4597	amino acid ABC transporter
PMA3_RS04280	COG0765	amino acid transport
PMA3_RS04285	COG1126	abc transporter atp-binding protein
PMA3_RS04290	COG2186	Transcriptional regulator
PMA3_RS04295	COG2807	transmembrane transport
PMA3_RS04305	COG2827	Endonuclease containing a URI domain
PMA3_RS04320	COG3081	Nucleoid-associated protein
PMA3_RS04330	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PMA3_RS04335	COG0525	valine-tRNA ligase activity
PMA3_RS04350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PMA3_RS04355	COG0795	lipopolysaccharide-transporting ATPase activity
PMA3_RS04360	COG0795	lipopolysaccharide-transporting ATPase activity
PMA3_RS04365	COG0481	GTPase activity
PMA3_RS04370	COG0681	Belongs to the peptidase S26 family
PMA3_RS04375	COG0571	ribonuclease III activity
PMA3_RS04380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PMA3_RS04385	COG1381	Involved in DNA repair and RecF pathway recombination
PMA3_RS04390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PMA3_RS04395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PMA3_RS04400	COG0047	phosphoribosylformylglycinamidine synthase activity
PMA3_RS04400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMA3_RS04405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PMA3_RS04420	COG0494	nUDIX hydrolase
PMA3_RS04435	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PMA3_RS04440	COG0477	Major facilitator Superfamily
PMA3_RS04445	COG4536	flavin adenine dinucleotide binding
PMA3_RS04455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMA3_RS04460	COG0228	four-way junction DNA binding
PMA3_RS04465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PMA3_RS04470	COG0336	Belongs to the RNA methyltransferase TrmD family
PMA3_RS04475	COG0335	large ribosomal subunit rRNA binding
PMA3_RS04480	COG4974	Belongs to the 'phage' integrase family
PMA3_RS04500	COG2205	protein histidine kinase activity
PMA3_RS04500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS04515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PMA3_RS04530	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS04535	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PMA3_RS04545	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS04550	COG1177	transmembrane transport
PMA3_RS04555	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS04560	COG3842	ATPase activity
PMA3_RS04565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PMA3_RS04585	COG0457	Tetratricopeptide repeat
PMA3_RS04585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PMA3_RS04600	COG2201	protein-glutamate methylesterase activity
PMA3_RS04605	COG5001	Diguanylate cyclase
PMA3_RS04605	COG4251	negative regulation of phosphorylation
PMA3_RS04605	COG3706	GGDEF domain
PMA3_RS04605	COG2203	Gaf domain
PMA3_RS04610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PMA3_RS04615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PMA3_RS04635	COG1073	alpha beta
PMA3_RS04645	COG2885	chlorophyll binding
PMA3_RS04660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PMA3_RS04665	COG0563	adenylate kinase activity
PMA3_RS04670	COG1214	PFAM Peptidase M22, glycoprotease
PMA3_RS04680	COG1801	Protein of unknown function DUF72
PMA3_RS04700	COG0742	ribosomal rna small subunit methyltransferase
PMA3_RS04710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS04715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMA3_RS04730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PMA3_RS04750	COG2937	Belongs to the GPAT DAPAT family
PMA3_RS04765	COG2226	methyltransferase
PMA3_RS04770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PMA3_RS04780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PMA3_RS04785	COG2166	iron-sulfur cluster assembly
PMA3_RS04790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PMA3_RS04795	COG2171	N-acyltransferase activity
PMA3_RS04800	COG1393	Belongs to the ArsC family
PMA3_RS04810	COG0436	Aminotransferase
PMA3_RS04815	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PMA3_RS04820	COG0024	Methionine aminopeptidase
PMA3_RS04825	COG0052	Belongs to the universal ribosomal protein uS2 family
PMA3_RS04830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PMA3_RS04835	COG0528	UMP kinase activity
PMA3_RS04840	COG0233	cytoplasmic translational termination
PMA3_RS04845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PMA3_RS04855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PMA3_RS04875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PMA3_RS04880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PMA3_RS04885	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PMA3_RS04890	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PMA3_RS04895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMA3_RS04900	COG0587	DNA-directed DNA polymerase activity
PMA3_RS04905	COG0825	malonyl-CoA metabolic process
PMA3_RS04915	COG0504	CTP synthase activity
PMA3_RS04920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PMA3_RS04925	COG0148	phosphopyruvate hydratase activity
PMA3_RS04935	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PMA3_RS04945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PMA3_RS04950	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PMA3_RS04955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PMA3_RS04960	COG0585	pseudouridine synthase activity
PMA3_RS04965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PMA3_RS04970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PMA3_RS04990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PMA3_RS04995	COG1546	Belongs to the CinA family
PMA3_RS05000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PMA3_RS05005	COG2137	regulation of response to DNA damage stimulus
PMA3_RS05025	COG3148	PFAM DTW domain containing protein
PMA3_RS05040	COG0583	DNA-binding transcription factor activity
PMA3_RS05055	COG4807	Protein conserved in bacteria
PMA3_RS05060	COG1187	pseudouridine synthase activity
PMA3_RS05070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PMA3_RS05075	COG3158	transport of potassium into the cell
PMA3_RS05105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PMA3_RS05115	COG0442	prolyl-tRNA aminoacylation
PMA3_RS05135	COG1278	Cold shock
PMA3_RS05140	COG0717	Belongs to the dCTP deaminase family
PMA3_RS05155	COG1201	RNA secondary structure unwinding
PMA3_RS05160	COG4598	ABC transporter
PMA3_RS05180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS05185	COG1793	dna ligase
PMA3_RS05195	COG2366	antibiotic biosynthetic process
PMA3_RS05200	COG0653	protein targeting
PMA3_RS05210	COG3012	SEC-C Motif Domain Protein
PMA3_RS05240	COG1199	ATP-dependent helicase activity
PMA3_RS05250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PMA3_RS05255	COG2885	chlorophyll binding
PMA3_RS05260	COG0259	pyridoxamine-phosphate oxidase activity
PMA3_RS05275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PMA3_RS05285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PMA3_RS05305	COG0583	DNA-binding transcription factor activity
PMA3_RS05340	COG2084	Dehydrogenase
PMA3_RS05345	COG2271	Major facilitator Superfamily
PMA3_RS05350	COG3547	Transposase (IS116 IS110 IS902 family)
PMA3_RS05355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PMA3_RS05370	COG0306	phosphate transporter
PMA3_RS05380	COG1414	Transcriptional regulator
PMA3_RS05385	COG2814	Major facilitator Superfamily
PMA3_RS05390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PMA3_RS05395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PMA3_RS05400	COG0183	Belongs to the thiolase family
PMA3_RS05405	COG3485	protocatechuate 3,4-dioxygenase
PMA3_RS05410	COG3485	protocatechuate 3,4-dioxygenase
PMA3_RS05415	COG0477	Major facilitator Superfamily
PMA3_RS05425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PMA3_RS05430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PMA3_RS05455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS05475	COG3795	YCII-related domain
PMA3_RS05480	COG4941	Belongs to the sigma-70 factor family
PMA3_RS05485	COG0583	DNA-binding transcription factor activity
PMA3_RS05505	COG0584	glycerophosphoryl diester phosphodiesterase
PMA3_RS05530	COG0154	amidase activity
PMA3_RS05540	COG1472	Belongs to the glycosyl hydrolase 3 family
PMA3_RS05565	COG1401	restriction endodeoxyribonuclease activity
PMA3_RS05575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMA3_RS05590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PMA3_RS05625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PMA3_RS05640	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS05645	COG3724	N-succinylarginine dihydrolase activity
PMA3_RS05655	COG2988	succinylglutamate desuccinylase activity
PMA3_RS05660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PMA3_RS05665	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PMA3_RS05670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PMA3_RS05675	COG0527	aspartate kinase activity
PMA3_RS05680	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PMA3_RS05700	COG2239	Acts as a magnesium transporter
PMA3_RS05765	COG0477	Major facilitator Superfamily
PMA3_RS05770	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PMA3_RS05780	COG2747	anti-sigma28 factor FlgM
PMA3_RS05790	COG0835	chemotaxis
PMA3_RS05790	COG0784	Response regulator, receiver
PMA3_RS05795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PMA3_RS05800	COG1815	bacterial-type flagellum-dependent cell motility
PMA3_RS05805	COG1558	bacterial-type flagellum-dependent cell motility
PMA3_RS05815	COG1749	Flagellar hook protein flgE
PMA3_RS05825	COG0745	RESPONSE REGULATOR receiver
PMA3_RS05830	COG2205	protein histidine kinase activity
PMA3_RS05855	COG4977	sequence-specific DNA binding
PMA3_RS05855	COG1917	Cupin 2, conserved barrel domain protein
PMA3_RS05860	COG1301	dicarboxylic acid transport
PMA3_RS05865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PMA3_RS05870	COG3091	SprT-like family
PMA3_RS05880	COG0037	tRNA processing
PMA3_RS05885	COG2818	Glycosylase
PMA3_RS05900	COG1393	Belongs to the ArsC family
PMA3_RS05905	COG3118	belongs to the thioredoxin family
PMA3_RS05920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMA3_RS05925	COG5002	protein histidine kinase activity
PMA3_RS05925	COG2205	protein histidine kinase activity
PMA3_RS05925	COG0784	Response regulator, receiver
PMA3_RS05950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMA3_RS05955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMA3_RS05960	COG3956	TIGRFAM MazG family protein
PMA3_RS05965	COG3122	Protein conserved in bacteria
PMA3_RS05980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PMA3_RS05985	COG5002	protein histidine kinase activity
PMA3_RS05985	COG2205	protein histidine kinase activity
PMA3_RS05985	COG0784	Response regulator, receiver
PMA3_RS05995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PMA3_RS06010	COG1022	Amp-dependent synthetase and ligase
PMA3_RS06030	COG0625	glutathione transferase activity
PMA3_RS06040	COG0628	permease
PMA3_RS06045	COG0284	orotidine-5'-phosphate decarboxylase activity
PMA3_RS06050	COG2130	NADP-dependent
PMA3_RS06055	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS06060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS06065	COG0840	transmembrane signaling receptor activity
PMA3_RS06095	COG1280	lysine exporter protein (LysE YggA)
PMA3_RS06105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PMA3_RS06130	COG0625	glutathione transferase activity
PMA3_RS06135	COG1131	(ABC) transporter
PMA3_RS06140	COG0842	Transport permease protein
PMA3_RS06155	COG0811	peptide transport
PMA3_RS06160	COG0848	biopolymer transport protein
PMA3_RS06165	COG1663	tetraacyldisaccharide 4'-kinase activity
PMA3_RS06170	COG2835	tetraacyldisaccharide 4'-kinase activity
PMA3_RS06175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PMA3_RS06180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMA3_RS06185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PMA3_RS06200	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PMA3_RS06200	COG3608	succinylglutamate desuccinylase aspartoacylase
PMA3_RS06210	COG1530	ribonuclease E activity
PMA3_RS06220	COG0546	phosphoglycolate phosphatase activity
PMA3_RS06225	COG0616	signal peptide processing
PMA3_RS06225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PMA3_RS06230	COG0424	maF-like protein
PMA3_RS06240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PMA3_RS06245	COG0416	fatty acid biosynthetic process
PMA3_RS06260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMA3_RS06265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PMA3_RS06275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PMA3_RS06280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMA3_RS06345	COG1846	Transcriptional regulator
PMA3_RS06415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS06420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMA3_RS06425	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS06440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PMA3_RS06440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PMA3_RS06595	COG1111	helicase
PMA3_RS06595	COG1205	dead DEAH box helicase
PMA3_RS06640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMA3_RS06655	COG0084	hydrolase, TatD family'
PMA3_RS06665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PMA3_RS06680	COG2186	Transcriptional regulator
PMA3_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS06695	COG1879	ABC-type sugar transport system periplasmic component
PMA3_RS06700	COG1129	ABC transporter
PMA3_RS06705	COG1172	Belongs to the binding-protein-dependent transport system permease family
PMA3_RS06710	COG2188	Transcriptional regulator
PMA3_RS06715	COG1397	ADP-ribosylglycohydrolase
PMA3_RS06725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMA3_RS06745	COG3734	2-keto-3-deoxy-galactonokinase
PMA3_RS06750	COG0800	Aldolase
PMA3_RS06755	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS06760	COG2271	Major facilitator Superfamily
PMA3_RS06765	COG1414	Transcriptional regulator
PMA3_RS06770	COG1064	alcohol dehydrogenase
PMA3_RS06775	COG2207	Transcriptional regulator
PMA3_RS06805	COG2885	chlorophyll binding
PMA3_RS06810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS06830	COG1368	sulfuric ester hydrolase activity
PMA3_RS06845	COG1742	UPF0060 membrane protein
PMA3_RS06850	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PMA3_RS06855	COG3089	Belongs to the UPF0270 family
PMA3_RS06865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMA3_RS06865	COG0189	ligase activity
PMA3_RS06870	COG0367	asparagine synthase
PMA3_RS06875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PMA3_RS06875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS06880	COG2326	polyphosphate kinase activity
PMA3_RS06885	COG0183	Belongs to the thiolase family
PMA3_RS06895	COG0697	spore germination
PMA3_RS06900	COG0114	fumarate hydratase activity
PMA3_RS06910	COG0271	Belongs to the BolA IbaG family
PMA3_RS06920	COG1054	Belongs to the UPF0176 family
PMA3_RS06940	COG5002	protein histidine kinase activity
PMA3_RS06940	COG5001	Diguanylate cyclase
PMA3_RS06950	COG2076	Multidrug Resistance protein
PMA3_RS06955	COG0385	Bile acid
PMA3_RS06960	COG2974	May be involved in recombination
PMA3_RS06985	COG0545	Peptidyl-prolyl cis-trans isomerase
PMA3_RS07020	COG4221	oxidoreductase activity
PMA3_RS07020	COG3321	synthase
PMA3_RS07020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PMA3_RS07020	COG0604	alcohol dehydrogenase
PMA3_RS07030	COG3842	ATPase activity
PMA3_RS07060	COG3384	dioxygenase
PMA3_RS07065	COG0500	methyltransferase
PMA3_RS07070	COG0501	Belongs to the peptidase M48B family
PMA3_RS07075	COG0436	Aminotransferase
PMA3_RS07080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMA3_RS07085	COG0386	Belongs to the glutathione peroxidase family
PMA3_RS07090	COG1846	Transcriptional regulator
PMA3_RS07105	COG1956	GAF domain-containing protein
PMA3_RS07110	COG2205	protein histidine kinase activity
PMA3_RS07110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS07115	COG2197	response regulator
PMA3_RS07145	COG0004	ammonium transporteR
PMA3_RS07165	COG0564	pseudouridine synthase activity
PMA3_RS07175	COG0746	molybdenum cofactor guanylyltransferase activity
PMA3_RS07180	COG0521	Mo-molybdopterin cofactor biosynthetic process
PMA3_RS07185	COG0303	'Molybdopterin
PMA3_RS07195	COG1597	lipid kinase activity
PMA3_RS07205	COG0633	Ferredoxin
PMA3_RS07205	COG3217	Mosc domain protein beta barrel domain protein
PMA3_RS07210	COG3123	guanosine phosphorylase activity
PMA3_RS07225	COG1024	Enoyl-CoA hydratase
PMA3_RS07230	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS07235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PMA3_RS07245	COG1309	transcriptional regulator
PMA3_RS07280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PMA3_RS07300	COG0642	Histidine kinase
PMA3_RS07325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PMA3_RS07390	COG0583	DNA-binding transcription factor activity
PMA3_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS07410	COG1309	transcriptional regulator
PMA3_RS07450	COG0768	penicillin binding
PMA3_RS07460	COG1132	(ABC) transporter
PMA3_RS07465	COG1404	Belongs to the peptidase S8 family
PMA3_RS07475	COG2130	NADP-dependent
PMA3_RS07480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PMA3_RS07485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PMA3_RS07490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMA3_RS07520	COG0348	domain, Protein
PMA3_RS07530	COG2010	Cytochrome c
PMA3_RS07545	COG3278	Belongs to the heme-copper respiratory oxidase family
PMA3_RS07550	COG2010	Cytochrome c
PMA3_RS07565	COG3278	Belongs to the heme-copper respiratory oxidase family
PMA3_RS07580	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS07585	COG0084	hydrolase, TatD family'
PMA3_RS07590	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PMA3_RS07595	COG2259	Doxx family
PMA3_RS07610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PMA3_RS07615	COG4181	ATPase activity
PMA3_RS07630	COG1376	ErfK ybiS ycfS ynhG family protein
PMA3_RS07665	COG0589	response to stress
PMA3_RS07675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PMA3_RS07690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMA3_RS07700	COG0583	DNA-binding transcription factor activity
PMA3_RS07715	COG3214	Protein conserved in bacteria
PMA3_RS07720	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PMA3_RS07730	COG1024	Enoyl-CoA hydratase
PMA3_RS07740	COG1473	amidohydrolase
PMA3_RS07745	COG0668	transmembrane transport
PMA3_RS07750	COG1362	aminopeptidase activity
PMA3_RS07760	COG0564	pseudouridine synthase activity
PMA3_RS07765	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PMA3_RS07770	COG2894	cell division
PMA3_RS07775	COG0850	regulation of cytokinetic process
PMA3_RS07780	COG1560	Kdo2-lipid A biosynthetic process
PMA3_RS07800	COG2233	PERMEase
PMA3_RS07810	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PMA3_RS07815	COG4266	Belongs to the allantoicase family
PMA3_RS07845	COG2252	PERMEase
PMA3_RS07855	COG0302	gtp cyclohydrolase
PMA3_RS07860	COG2840	Smr protein MutS2
PMA3_RS07885	COG1073	alpha beta
PMA3_RS07890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PMA3_RS07900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PMA3_RS07910	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS07920	COG2885	chlorophyll binding
PMA3_RS07925	COG0417	DNA replication proofreading
PMA3_RS07935	COG0656	L-ascorbic acid biosynthetic process
PMA3_RS07945	COG0730	response to heat
PMA3_RS07985	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PMA3_RS08025	COG0697	spore germination
PMA3_RS08030	COG0583	DNA-binding transcription factor activity
PMA3_RS08035	COG0826	peptidase U32
PMA3_RS08040	COG0628	permease
PMA3_RS08060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMA3_RS08065	COG3132	Protein of unknown function, DUF480
PMA3_RS08075	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PMA3_RS08085	COG0583	DNA-binding transcription factor activity
PMA3_RS08095	COG1253	flavin adenine dinucleotide binding
PMA3_RS08115	COG1686	Belongs to the peptidase S11 family
PMA3_RS08120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMA3_RS08140	COG0544	peptidyl-prolyl cis-trans isomerase activity
PMA3_RS08145	COG0740	serine-type endopeptidase activity
PMA3_RS08150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMA3_RS08155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PMA3_RS08160	COG0776	regulation of translation
PMA3_RS08165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMA3_RS08185	COG0446	pyridine nucleotide-disulphide oxidoreductase
PMA3_RS08185	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS08195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMA3_RS08200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PMA3_RS08205	COG0583	DNA-binding transcription factor activity
PMA3_RS08210	COG0583	DNA-binding transcription factor activity
PMA3_RS08215	COG2271	Major facilitator Superfamily
PMA3_RS08225	COG0217	transcriptional regulatory protein
PMA3_RS08235	COG3547	Transposase (IS116 IS110 IS902 family)
PMA3_RS08240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PMA3_RS08265	COG1177	transmembrane transport
PMA3_RS08270	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS08275	COG3842	ATPase activity
PMA3_RS08280	COG1414	Transcriptional regulator
PMA3_RS08300	COG3038	cytochrome b561
PMA3_RS08305	COG2866	Carboxypeptidase
PMA3_RS08315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMA3_RS08330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PMA3_RS08335	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS08340	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS08355	COG0789	Transcriptional regulator
PMA3_RS08360	COG0840	transmembrane signaling receptor activity
PMA3_RS08440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PMA3_RS08465	COG0438	transferase activity, transferring glycosyl groups
PMA3_RS08475	COG2089	acid synthase
PMA3_RS08480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMA3_RS08485	COG1083	cytidylyl-transferase
PMA3_RS08490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PMA3_RS08495	COG1086	Polysaccharide biosynthesis protein
PMA3_RS08515	COG3206	protein involved in exopolysaccharide biosynthesis
PMA3_RS08515	COG0489	protein tyrosine kinase activity
PMA3_RS08520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMA3_RS08555	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PMA3_RS08560	COG0425	Belongs to the sulfur carrier protein TusA family
PMA3_RS08570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PMA3_RS08580	COG1132	(ABC) transporter
PMA3_RS08585	COG0741	lytic transglycosylase activity
PMA3_RS08590	COG0488	(ABC) transporter
PMA3_RS08595	COG0589	response to stress
PMA3_RS08605	COG1250	3-hydroxyacyl-CoA dehydrogenase
PMA3_RS08605	COG1024	Enoyl-CoA hydratase
PMA3_RS08610	COG0183	Belongs to the thiolase family
PMA3_RS08655	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PMA3_RS08660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PMA3_RS08670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMA3_RS08680	COG1477	protein flavinylation
PMA3_RS08685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMA3_RS08690	COG0584	glycerophosphoryl diester phosphodiesterase
PMA3_RS08700	COG4591	ABC-type transport system involved in lipoprotein release permease component
PMA3_RS08705	COG1136	(ABC) transporter
PMA3_RS08710	COG4591	ABC-type transport system involved in lipoprotein release permease component
PMA3_RS08730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PMA3_RS08730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PMA3_RS08740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMA3_RS08745	COG2853	Lipoprotein
PMA3_RS08750	COG2204	response regulator
PMA3_RS08760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PMA3_RS08765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMA3_RS08790	COG3958	Transketolase
PMA3_RS08795	COG3959	Transketolase, thiamine diphosphate binding domain
PMA3_RS08800	COG2271	Major facilitator Superfamily
PMA3_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS08810	COG0583	DNA-binding transcription factor activity
PMA3_RS08830	COG2989	Protein conserved in bacteria
PMA3_RS08860	COG0708	Exodeoxyribonuclease III
PMA3_RS08870	COG2233	PERMEase
PMA3_RS08885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMA3_RS08910	COG0556	nucleotide-excision repair
PMA3_RS08915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMA3_RS08945	COG0596	Alpha beta hydrolase
PMA3_RS08955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMA3_RS08965	COG4589	Belongs to the CDS family
PMA3_RS08980	COG0671	phosphoesterase, PA-phosphatase related
PMA3_RS08980	COG2453	phosphatase
PMA3_RS08985	COG2267	carboxylic ester hydrolase activity
PMA3_RS08990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMA3_RS09015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PMA3_RS09020	COG0066	3-isopropylmalate dehydratase activity
PMA3_RS09025	COG2226	methyltransferase
PMA3_RS09030	COG0473	3-isopropylmalate dehydrogenase activity
PMA3_RS09055	COG0135	phosphoribosylanthranilate isomerase activity
PMA3_RS09060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PMA3_RS09065	COG0285	dihydrofolate synthase activity
PMA3_RS09070	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PMA3_RS09075	COG1286	toxin biosynthetic process
PMA3_RS09115	COG3712	iron ion homeostasis
PMA3_RS09120	COG4774	siderophore transport
PMA3_RS09125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PMA3_RS09130	COG4264	IucA IucC family
PMA3_RS09135	COG0019	diaminopimelate decarboxylase activity
PMA3_RS09140	COG2814	Major facilitator Superfamily
PMA3_RS09155	COG4264	IucA IucC family
PMA3_RS09160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PMA3_RS09165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMA3_RS09170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMA3_RS09175	COG1120	ATPase activity
PMA3_RS09185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PMA3_RS09190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS09260	COG0288	reversible hydration of carbon dioxide
PMA3_RS09270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PMA3_RS09300	COG1129	ABC transporter
PMA3_RS09305	COG1172	Belongs to the binding-protein-dependent transport system permease family
PMA3_RS09310	COG1609	Transcriptional regulator
PMA3_RS09315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMA3_RS09320	COG1869	D-ribose catabolic process
PMA3_RS09345	COG1278	Cold shock
PMA3_RS09355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMA3_RS09360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PMA3_RS09365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PMA3_RS09370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PMA3_RS09375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PMA3_RS09380	COG0072	phenylalanine-tRNA ligase activity
PMA3_RS09385	COG0776	regulation of translation
PMA3_RS09405	COG2072	flavoprotein involved in K transport
PMA3_RS09425	COG0492	ferredoxin-NADP+ reductase activity
PMA3_RS09435	COG0640	Transcriptional regulator
PMA3_RS09445	COG0798	PFAM Bile acid sodium symporter
PMA3_RS09450	COG0431	NADPH-dependent FMN reductase
PMA3_RS09460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PMA3_RS09475	COG2423	ornithine cyclodeaminase activity
PMA3_RS09480	COG1126	abc transporter atp-binding protein
PMA3_RS09485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS09495	COG4215	(ABC) transporter
PMA3_RS09515	COG0473	3-isopropylmalate dehydrogenase activity
PMA3_RS09525	COG0281	malic enzyme
PMA3_RS09540	COG0659	secondary active sulfate transmembrane transporter activity
PMA3_RS09560	COG0747	negative chemotaxis
PMA3_RS09565	COG0601	transmembrane transport
PMA3_RS09570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMA3_RS09580	COG4608	Belongs to the ABC transporter superfamily
PMA3_RS09595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PMA3_RS09615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMA3_RS09640	COG0460	homoserine dehydrogenase
PMA3_RS09645	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS09650	COG1113	amino acid transport
PMA3_RS09655	COG0626	cystathionine gamma-synthase activity
PMA3_RS09685	COG1522	sequence-specific DNA binding
PMA3_RS09695	COG1473	amidohydrolase
PMA3_RS09720	COG1454	alcohol dehydrogenase
PMA3_RS09735	COG0598	Magnesium transport protein CorA
PMA3_RS09765	COG2135	peptidase activity
PMA3_RS09815	COG0477	Major facilitator Superfamily
PMA3_RS09820	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS09825	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS09835	COG0163	prenyltransferase activity
PMA3_RS09845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PMA3_RS09845	COG3608	succinylglutamate desuccinylase aspartoacylase
PMA3_RS09860	COG2135	peptidase activity
PMA3_RS09865	COG3485	protocatechuate 3,4-dioxygenase
PMA3_RS09870	COG3485	protocatechuate 3,4-dioxygenase
PMA3_RS09875	COG0583	DNA-binding transcription factor activity
PMA3_RS09935	COG0589	response to stress
PMA3_RS09955	COG0589	response to stress
PMA3_RS10000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMA3_RS10005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS10010	COG0251	oxidation-reduction process
PMA3_RS10020	COG4175	Glycine betaine
PMA3_RS10025	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS10030	COG2113	Glycine betaine
PMA3_RS10035	COG0006	proline dipeptidase activity
PMA3_RS10050	COG0583	DNA-binding transcription factor activity
PMA3_RS10055	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS10060	COG2207	Transcriptional regulator
PMA3_RS10060	COG0662	Cupin 2, conserved barrel domain protein
PMA3_RS10070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS10075	COG1598	PFAM Uncharacterised protein family UPF0150
PMA3_RS10100	COG1802	Transcriptional regulator
PMA3_RS10105	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS10110	COG3246	L-lysine catabolic process to acetate
PMA3_RS10135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PMA3_RS10150	COG1234	tRNA 3'-trailer cleavage
PMA3_RS10155	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS10165	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS10170	COG2271	Major facilitator Superfamily
PMA3_RS10195	COG0583	DNA-binding transcription factor activity
PMA3_RS10205	COG1301	dicarboxylic acid transport
PMA3_RS10220	COG1064	alcohol dehydrogenase
PMA3_RS10225	COG2207	Transcriptional regulator
PMA3_RS10230	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS10245	COG4638	Rieske (2fe-2S)
PMA3_RS10250	COG0583	DNA-binding transcription factor activity
PMA3_RS10255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMA3_RS10260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS10265	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS10275	COG3448	diguanylate cyclase activity
PMA3_RS10275	COG4175	Glycine betaine
PMA3_RS10280	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS10285	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS10340	COG2851	Citrate transporter
PMA3_RS10355	COG2271	Major facilitator Superfamily
PMA3_RS10360	COG1082	Xylose isomerase domain protein TIM barrel
PMA3_RS10375	COG2175	clavaminate synthase activity
PMA3_RS10380	COG3246	L-lysine catabolic process to acetate
PMA3_RS10385	COG0477	Major facilitator Superfamily
PMA3_RS10400	COG2855	membrane
PMA3_RS10425	COG4447	cellulose binding
PMA3_RS10435	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS10440	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS10515	COG1120	ATPase activity
PMA3_RS10520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PMA3_RS10525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PMA3_RS10630	COG2271	Major facilitator Superfamily
PMA3_RS10650	COG0583	DNA-binding transcription factor activity
PMA3_RS10655	COG0066	3-isopropylmalate dehydratase activity
PMA3_RS10665	COG2353	YceI-like domain
PMA3_RS10685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PMA3_RS10690	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
PMA3_RS10695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PMA3_RS10710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMA3_RS10725	COG0300	oxidoreductase activity
PMA3_RS10730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PMA3_RS10745	COG0583	DNA-binding transcription factor activity
PMA3_RS10760	COG2271	Major facilitator Superfamily
PMA3_RS10765	COG0579	oxidoreductase
PMA3_RS10785	COG0583	DNA-binding transcription factor activity
PMA3_RS10795	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS10805	COG5002	protein histidine kinase activity
PMA3_RS10810	COG0745	RESPONSE REGULATOR receiver
PMA3_RS10830	COG0840	transmembrane signaling receptor activity
PMA3_RS10865	COG1320	monovalent cation:proton antiporter activity
PMA3_RS10870	COG2212	antiporter activity
PMA3_RS10880	COG0651	ATP synthesis coupled electron transport
PMA3_RS10885	COG1006	Multisubunit Na H antiporter MnhC subunit
PMA3_RS10890	COG2111	Na H antiporter
PMA3_RS10890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PMA3_RS10920	COG1611	Belongs to the LOG family
PMA3_RS10930	COG2203	Gaf domain
PMA3_RS10930	COG4251	negative regulation of phosphorylation
PMA3_RS10930	COG5001	Diguanylate cyclase
PMA3_RS10930	COG3706	GGDEF domain
PMA3_RS10960	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS10965	COG4829	muconolactone delta-isomerase
PMA3_RS10970	COG3485	protocatechuate 3,4-dioxygenase
PMA3_RS11005	COG0494	nUDIX hydrolase
PMA3_RS11020	COG1690	Belongs to the RtcB family
PMA3_RS11035	COG1959	2 iron, 2 sulfur cluster binding
PMA3_RS11045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS11055	COG0174	glutamine synthetase
PMA3_RS11065	COG0446	pyridine nucleotide-disulphide oxidoreductase
PMA3_RS11065	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PMA3_RS11080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMA3_RS11100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PMA3_RS11105	COG2218	PFAM glutamate synthase alpha subunit domain protein
PMA3_RS11110	COG0069	glutamate synthase activity
PMA3_RS11115	COG0004	ammonium transporteR
PMA3_RS11120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMA3_RS11130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PMA3_RS11145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PMA3_RS11155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PMA3_RS11165	COG3850	Histidine kinase
PMA3_RS11170	COG2197	response regulator
PMA3_RS11180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PMA3_RS11185	COG1335	isochorismatase
PMA3_RS11190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PMA3_RS11200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PMA3_RS11205	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PMA3_RS11210	COG3842	ATPase activity
PMA3_RS11220	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS11230	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PMA3_RS11245	COG2186	Transcriptional regulator
PMA3_RS11250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PMA3_RS11260	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS11265	COG2267	carboxylic ester hydrolase activity
PMA3_RS11370	COG1397	ADP-ribosylglycohydrolase
PMA3_RS11375	COG2369	cell adhesion
PMA3_RS11395	COG3209	COG3209 Rhs family protein
PMA3_RS11410	COG3209	COG3209 Rhs family protein
PMA3_RS11440	COG1966	Carbon starvation protein
PMA3_RS11445	COG2879	small protein
PMA3_RS11450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMA3_RS11460	COG2135	peptidase activity
PMA3_RS11560	COG2271	Major facilitator Superfamily
PMA3_RS11565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PMA3_RS11570	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS11605	COG3179	chitinase
PMA3_RS11630	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11645	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11650	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11655	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11675	COG2814	Major facilitator Superfamily
PMA3_RS11680	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS11685	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS11735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PMA3_RS11740	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PMA3_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS11800	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11805	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11825	COG1024	Enoyl-CoA hydratase
PMA3_RS11835	COG1024	Enoyl-CoA hydratase
PMA3_RS11840	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11845	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS11850	COG0183	Belongs to the thiolase family
PMA3_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS11870	COG0183	Belongs to the thiolase family
PMA3_RS11890	COG4221	oxidoreductase activity
PMA3_RS11925	COG0175	sulfate reduction
PMA3_RS11950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PMA3_RS11955	COG0745	RESPONSE REGULATOR receiver
PMA3_RS11960	COG0784	Response regulator, receiver
PMA3_RS11960	COG2205	protein histidine kinase activity
PMA3_RS11990	COG1522	sequence-specific DNA binding
PMA3_RS11995	COG0697	spore germination
PMA3_RS12015	COG2188	Transcriptional regulator
PMA3_RS12020	COG2081	HI0933 family
PMA3_RS12030	COG4521	taurine ABC transporter
PMA3_RS12035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMA3_RS12055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMA3_RS12070	COG0587	DNA-directed DNA polymerase activity
PMA3_RS12075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PMA3_RS12080	COG0402	S-adenosylhomocysteine deaminase activity
PMA3_RS12095	COG1177	transmembrane transport
PMA3_RS12100	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS12105	COG3842	ATPase activity
PMA3_RS12115	COG0784	Response regulator, receiver
PMA3_RS12115	COG4191	Histidine kinase
PMA3_RS12125	COG0784	Response regulator, receiver
PMA3_RS12125	COG4191	Histidine kinase
PMA3_RS12140	COG2172	sigma factor antagonist activity
PMA3_RS12145	COG1366	Belongs to the anti-sigma-factor antagonist family
PMA3_RS12150	COG1366	Belongs to the anti-sigma-factor antagonist family
PMA3_RS12200	COG0616	signal peptide processing
PMA3_RS12225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMA3_RS12245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PMA3_RS12245	COG0316	Belongs to the HesB IscA family
PMA3_RS12300	COG0583	DNA-binding transcription factor activity
PMA3_RS12305	COG1253	flavin adenine dinucleotide binding
PMA3_RS12310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS12315	COG0765	amino acid transport
PMA3_RS12320	COG0765	amino acid transport
PMA3_RS12345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMA3_RS12350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMA3_RS12365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PMA3_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS12375	COG2610	gluconate transmembrane transporter activity
PMA3_RS12380	COG3604	Transcriptional regulator
PMA3_RS12385	COG4172	Belongs to the ABC transporter superfamily
PMA3_RS12390	COG4239	(ABC) transporter, permease
PMA3_RS12395	COG4174	ABC transporter (Permease)
PMA3_RS12400	COG4166	transmembrane transport
PMA3_RS12405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMA3_RS12410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PMA3_RS12415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PMA3_RS12420	COG2197	response regulator
PMA3_RS12425	COG0322	excinuclease ABC activity
PMA3_RS12455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PMA3_RS12465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMA3_RS12490	COG0589	response to stress
PMA3_RS12495	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PMA3_RS12505	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMA3_RS12530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMA3_RS12545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PMA3_RS12555	COG2271	Major facilitator Superfamily
PMA3_RS12560	COG1335	isochorismatase
PMA3_RS12565	COG3473	Maleate cis-trans isomerase
PMA3_RS12570	COG0596	Alpha beta hydrolase
PMA3_RS12575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMA3_RS12580	COG2309	aminopeptidase activity
PMA3_RS12585	COG1846	Transcriptional regulator
PMA3_RS12590	COG2080	2 iron, 2 sulfur cluster binding
PMA3_RS12595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PMA3_RS12595	COG2010	Cytochrome c
PMA3_RS12600	COG1309	transcriptional regulator
PMA3_RS12605	COG1858	cytochrome C peroxidase
PMA3_RS12610	COG1858	cytochrome C peroxidase
PMA3_RS12670	COG1473	amidohydrolase
PMA3_RS12680	COG1566	PFAM secretion protein HlyD family protein
PMA3_RS12695	COG0446	pyridine nucleotide-disulphide oxidoreductase
PMA3_RS12695	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS12700	COG2113	Glycine betaine
PMA3_RS12710	COG0019	diaminopimelate decarboxylase activity
PMA3_RS12725	COG3340	Belongs to the peptidase S51 family
PMA3_RS12740	COG1917	Cupin 2, conserved barrel domain protein
PMA3_RS12740	COG1396	sequence-specific DNA binding
PMA3_RS12745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PMA3_RS12745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PMA3_RS12790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMA3_RS12810	COG0477	Major facilitator Superfamily
PMA3_RS12820	COG3005	denitrification pathway
PMA3_RS12830	COG0243	molybdopterin cofactor binding
PMA3_RS12835	COG3062	negative regulation of establishment of protein localization
PMA3_RS12840	COG4459	periplasmic nitrate reductase
PMA3_RS12850	COG3781	membrane
PMA3_RS12870	COG2879	small protein
PMA3_RS12895	COG2259	Doxx family
PMA3_RS12900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PMA3_RS12905	COG2823	Periplasmic or secreted lipoprotein
PMA3_RS12910	COG0288	reversible hydration of carbon dioxide
PMA3_RS12915	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PMA3_RS12920	COG0583	DNA-binding transcription factor activity
PMA3_RS12940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMA3_RS12955	COG1304	FMN binding
PMA3_RS12990	COG4221	oxidoreductase activity
PMA3_RS13000	COG1022	Amp-dependent synthetase and ligase
PMA3_RS13010	COG3038	cytochrome b561
PMA3_RS13015	COG4335	DNA alkylation repair
PMA3_RS13075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PMA3_RS13080	COG0596	Alpha beta hydrolase
PMA3_RS13085	COG1238	metal cluster binding
PMA3_RS13105	COG2366	antibiotic biosynthetic process
PMA3_RS13165	COG0010	Belongs to the arginase family
PMA3_RS13170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PMA3_RS13190	COG2194	sulfuric ester hydrolase activity
PMA3_RS13195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PMA3_RS13200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMA3_RS13205	COG0561	phosphatase activity
PMA3_RS13210	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PMA3_RS13225	COG2204	response regulator
PMA3_RS13270	COG0840	transmembrane signaling receptor activity
PMA3_RS13275	COG1968	undecaprenyl-diphosphatase activity
PMA3_RS13290	COG0583	DNA-binding transcription factor activity
PMA3_RS13295	COG0583	DNA-binding transcription factor activity
PMA3_RS13315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PMA3_RS13330	COG3547	Transposase (IS116 IS110 IS902 family)
PMA3_RS13335	COG0488	(ABC) transporter
PMA3_RS13345	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PMA3_RS13350	COG2133	pyrroloquinoline quinone binding
PMA3_RS13370	COG1070	Carbohydrate kinase
PMA3_RS13375	COG0246	Mannitol dehydrogenase
PMA3_RS13390	COG1175	transmembrane transport
PMA3_RS13415	COG0784	Response regulator, receiver
PMA3_RS13415	COG2198	Histidine kinase
PMA3_RS13415	COG2205	protein histidine kinase activity
PMA3_RS13420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PMA3_RS13430	COG2198	Histidine kinase
PMA3_RS13430	COG2205	protein histidine kinase activity
PMA3_RS13430	COG0784	Response regulator, receiver
PMA3_RS13445	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PMA3_RS13455	COG1289	transmembrane transporter activity
PMA3_RS13465	COG1566	PFAM secretion protein HlyD family protein
PMA3_RS13500	COG0589	response to stress
PMA3_RS13505	COG0531	amino acid
PMA3_RS13515	COG0589	response to stress
PMA3_RS13525	COG2863	cytochrome
PMA3_RS13530	COG3258	Cytochrome c
PMA3_RS13555	COG1477	protein flavinylation
PMA3_RS13595	COG0667	Aldo Keto reductase
PMA3_RS13615	COG2207	Transcriptional regulator
PMA3_RS13640	COG0604	alcohol dehydrogenase
PMA3_RS13640	COG3321	synthase
PMA3_RS13640	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS13650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS13665	COG0210	DNA helicase
PMA3_RS13680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS13695	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS13700	COG0583	DNA-binding transcription factor activity
PMA3_RS13705	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS13710	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
PMA3_RS13710	COG0028	Belongs to the TPP enzyme family
PMA3_RS13735	COG0477	Major facilitator Superfamily
PMA3_RS13770	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PMA3_RS13785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PMA3_RS13785	COG1199	ATP-dependent helicase activity
PMA3_RS13825	COG1058	Belongs to the CinA family
PMA3_RS13825	COG1546	Belongs to the CinA family
PMA3_RS13835	COG2323	membrane
PMA3_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS13845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PMA3_RS13850	COG3383	formate dehydrogenase (NAD+) activity
PMA3_RS13850	COG0243	molybdopterin cofactor binding
PMA3_RS13855	COG3383	formate dehydrogenase (NAD+) activity
PMA3_RS13855	COG0243	molybdopterin cofactor binding
PMA3_RS13860	COG0437	4 iron, 4 sulfur cluster binding
PMA3_RS13865	COG2864	formate dehydrogenase
PMA3_RS13870	COG3058	Necessary for formate dehydrogenase activity
PMA3_RS13875	COG1921	L-seryl-tRNASec selenium transferase activity
PMA3_RS13880	COG3276	selenocysteine insertion sequence binding
PMA3_RS13890	COG3243	poly(R)-hydroxyalkanoic acid synthase
PMA3_RS13900	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS13925	COG0714	Associated with various cellular activities
PMA3_RS13930	COG3256	nitric oxide reductase
PMA3_RS13935	COG2010	Cytochrome c
PMA3_RS13950	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS13955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMA3_RS13965	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS13970	COG4191	Histidine kinase
PMA3_RS13975	COG4566	intracellular signal transduction
PMA3_RS13980	COG0628	permease
PMA3_RS14000	COG3665	Urea carboxylase-associated protein
PMA3_RS14005	COG0583	DNA-binding transcription factor activity
PMA3_RS14060	COG1566	PFAM secretion protein HlyD family protein
PMA3_RS14120	COG0583	DNA-binding transcription factor activity
PMA3_RS14125	COG0247	lactate metabolic process
PMA3_RS14125	COG0277	FAD linked oxidase domain protein
PMA3_RS14140	COG2855	membrane
PMA3_RS14150	COG2814	Major facilitator Superfamily
PMA3_RS14155	COG3246	L-lysine catabolic process to acetate
PMA3_RS14165	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS14190	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS14195	COG2249	NAD(P)H dehydrogenase (quinone) activity
PMA3_RS14200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PMA3_RS14205	COG0477	Major facilitator Superfamily
PMA3_RS14215	COG4638	Rieske (2fe-2S)
PMA3_RS14220	COG0583	DNA-binding transcription factor activity
PMA3_RS14240	COG2814	Major facilitator Superfamily
PMA3_RS14250	COG1113	amino acid transport
PMA3_RS14255	COG2423	ornithine cyclodeaminase activity
PMA3_RS14265	COG1522	sequence-specific DNA binding
PMA3_RS14285	COG0563	adenylate kinase activity
PMA3_RS14295	COG0583	DNA-binding transcription factor activity
PMA3_RS14305	COG3791	Glutathione-dependent formaldehyde-activating
PMA3_RS14315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS14320	COG2271	Major facilitator Superfamily
PMA3_RS14325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMA3_RS14350	COG3192	ethanolamine utilization protein
PMA3_RS14375	COG2271	Major facilitator Superfamily
PMA3_RS14380	COG2186	Transcriptional regulator
PMA3_RS14390	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS14395	COG2186	Transcriptional regulator
PMA3_RS14400	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS14415	COG1538	Outer membrane efflux protein
PMA3_RS14435	COG2356	endonuclease I
PMA3_RS14440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMA3_RS14450	COG3284	Transcriptional regulator
PMA3_RS14475	COG0559	Belongs to the binding-protein-dependent transport system permease family
PMA3_RS14485	COG1024	Enoyl-CoA hydratase
PMA3_RS14500	COG4372	Transposase
PMA3_RS14510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PMA3_RS14535	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS14540	COG0640	Transcriptional regulator
PMA3_RS14550	COG0583	DNA-binding transcription factor activity
PMA3_RS14570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PMA3_RS14570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PMA3_RS14575	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PMA3_RS14580	COG0542	response to heat
PMA3_RS14590	COG1522	sequence-specific DNA binding
PMA3_RS14595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PMA3_RS14605	COG0006	proline dipeptidase activity
PMA3_RS14610	COG2271	Major facilitator Superfamily
PMA3_RS14615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS14620	COG1126	abc transporter atp-binding protein
PMA3_RS14625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMA3_RS14635	COG2084	Dehydrogenase
PMA3_RS14640	COG3622	Belongs to the hyi family
PMA3_RS14645	COG3960	tartronate-semialdehyde synthase activity
PMA3_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS14665	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PMA3_RS14670	COG0523	cobalamin synthesis protein
PMA3_RS14685	COG0446	pyridine nucleotide-disulphide oxidoreductase
PMA3_RS14685	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS14690	COG0583	DNA-binding transcription factor activity
PMA3_RS14715	COG0174	glutamine synthetase
PMA3_RS14725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS14735	COG2995	paraquat-inducible protein a
PMA3_RS14740	COG3008	intermembrane lipid transfer
PMA3_RS14760	COG3842	ATPase activity
PMA3_RS14765	COG4974	Belongs to the 'phage' integrase family
PMA3_RS14790	COG0165	Argininosuccinate lyase
PMA3_RS14795	COG0765	amino acid transport
PMA3_RS14805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS14820	COG2814	Major facilitator Superfamily
PMA3_RS14830	COG1024	Enoyl-CoA hydratase
PMA3_RS14835	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS14840	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS14845	COG0183	Belongs to the thiolase family
PMA3_RS14855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PMA3_RS14860	COG2207	Transcriptional regulator
PMA3_RS14865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMA3_RS14885	COG2816	NAD+ diphosphatase activity
PMA3_RS14890	COG1024	Enoyl-CoA hydratase
PMA3_RS14895	COG0297	glycogen (starch) synthase activity
PMA3_RS14900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PMA3_RS14935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PMA3_RS14945	COG3568	Endonuclease Exonuclease Phosphatase
PMA3_RS14965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PMA3_RS14970	COG0366	Alpha amylase catalytic
PMA3_RS14980	COG1285	pathogenesis
PMA3_RS14990	COG0348	domain, Protein
PMA3_RS14995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS15010	COG1538	Outer membrane efflux protein
PMA3_RS15015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMA3_RS15040	COG3795	YCII-related domain
PMA3_RS15055	COG4104	PAAR repeat-containing protein
PMA3_RS15070	COG0714	Associated with various cellular activities
PMA3_RS15090	COG2304	oxidoreductase activity
PMA3_RS15120	COG0484	heat shock protein binding
PMA3_RS15135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PMA3_RS15170	COG0714	Associated with various cellular activities
PMA3_RS15200	COG0488	(ABC) transporter
PMA3_RS15205	COG0420	3'-5' exonuclease activity
PMA3_RS15235	COG2706	6-phosphogluconolactonase activity
PMA3_RS15245	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS15265	COG1609	Transcriptional regulator
PMA3_RS15305	COG0308	aminopeptidase N
PMA3_RS15315	COG3139	Protein of unknown function (DUF1315)
PMA3_RS15320	COG0705	Rhomboid family
PMA3_RS15325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PMA3_RS15330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PMA3_RS15340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PMA3_RS15345	COG0640	Transcriptional regulator
PMA3_RS15350	COG0431	NADPH-dependent FMN reductase
PMA3_RS15375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PMA3_RS15380	COG0328	RNA-DNA hybrid ribonuclease activity
PMA3_RS15390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PMA3_RS15395	COG1388	LysM domain
PMA3_RS15395	COG0741	lytic transglycosylase activity
PMA3_RS15400	COG4166	transmembrane transport
PMA3_RS15405	COG4166	transmembrane transport
PMA3_RS15410	COG4174	ABC transporter (Permease)
PMA3_RS15415	COG4239	(ABC) transporter, permease
PMA3_RS15420	COG4172	Belongs to the ABC transporter superfamily
PMA3_RS15440	COG3706	GGDEF domain
PMA3_RS15475	COG2169	Transcriptional regulator
PMA3_RS15475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PMA3_RS15485	COG3791	Glutathione-dependent formaldehyde-activating
PMA3_RS15500	COG0589	response to stress
PMA3_RS15515	COG0814	amino acid
PMA3_RS15535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMA3_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS15565	COG1953	Uracil, thiamine, allantoin
PMA3_RS15575	COG0493	'glutamate synthase
PMA3_RS15585	COG1309	transcriptional regulator
PMA3_RS15590	COG2372	response to copper ion
PMA3_RS15605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PMA3_RS15615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMA3_RS15645	COG0535	radical SAM domain protein
PMA3_RS15655	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PMA3_RS15670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PMA3_RS15705	COG4585	Histidine kinase
PMA3_RS15720	COG1131	(ABC) transporter
PMA3_RS15740	COG2205	protein histidine kinase activity
PMA3_RS15740	COG0784	Response regulator, receiver
PMA3_RS15755	COG0730	response to heat
PMA3_RS15765	COG1522	sequence-specific DNA binding
PMA3_RS15770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PMA3_RS15775	COG0022	dehydrogenase e1 component
PMA3_RS15785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMA3_RS15790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PMA3_RS15795	COG2205	protein histidine kinase activity
PMA3_RS15800	COG0745	RESPONSE REGULATOR receiver
PMA3_RS15805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS15810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMA3_RS15835	COG1609	Transcriptional regulator
PMA3_RS15845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMA3_RS15870	COG2197	response regulator
PMA3_RS15880	COG1929	Belongs to the glycerate kinase type-1 family
PMA3_RS15885	COG3835	regulator
PMA3_RS15890	COG0667	Aldo Keto reductase
PMA3_RS15905	COG2200	EAL domain
PMA3_RS15925	COG3634	alkyl hydroperoxide reductase activity
PMA3_RS15985	COG2169	Transcriptional regulator
PMA3_RS15985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PMA3_RS16010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PMA3_RS16050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PMA3_RS16070	COG5002	protein histidine kinase activity
PMA3_RS16070	COG5001	Diguanylate cyclase
PMA3_RS16070	COG3447	MASE1 domain protein
PMA3_RS16090	COG0583	DNA-binding transcription factor activity
PMA3_RS16100	COG3012	SEC-C Motif Domain Protein
PMA3_RS16125	COG0582	viral genome integration into host DNA
PMA3_RS16175	COG2181	nitrate reductase activity
PMA3_RS16180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PMA3_RS16185	COG1140	nitrate reductase beta subunit
PMA3_RS16190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PMA3_RS16195	COG2223	nitrite transmembrane transporter activity
PMA3_RS16205	COG3850	Histidine kinase
PMA3_RS16210	COG2197	response regulator
PMA3_RS16225	COG3154	lipid carrier protein
PMA3_RS16230	COG0826	peptidase U32
PMA3_RS16235	COG0826	peptidase U32
PMA3_RS16240	COG0303	'Molybdopterin
PMA3_RS16245	COG0521	Mo-molybdopterin cofactor biosynthetic process
PMA3_RS16255	COG3604	Transcriptional regulator
PMA3_RS16260	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PMA3_RS16275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMA3_RS16290	COG3256	nitric oxide reductase
PMA3_RS16295	COG2010	Cytochrome c
PMA3_RS16305	COG1845	cytochrome c oxidase, subunit III
PMA3_RS16310	COG0714	Associated with various cellular activities
PMA3_RS16325	COG2010	Cytochrome c
PMA3_RS16330	COG3391	amine dehydrogenase activity
PMA3_RS16355	COG0535	radical SAM domain protein
PMA3_RS16360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PMA3_RS16360	COG1648	precorrin-2 dehydrogenase activity
PMA3_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS16380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PMA3_RS16400	COG0348	domain, Protein
PMA3_RS16400	COG3901	Regulator of nitric oxide reductase transcription
PMA3_RS16420	COG0517	IMP dehydrogenase activity
PMA3_RS16425	COG2146	nitrite reductase [NAD(P)H] activity
PMA3_RS16425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMA3_RS16430	COG2146	nitrite reductase [NAD(P)H] activity
PMA3_RS16430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMA3_RS16440	COG1454	alcohol dehydrogenase
PMA3_RS16445	COG1024	Enoyl-CoA hydratase
PMA3_RS16450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PMA3_RS16455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PMA3_RS16460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PMA3_RS16470	COG3618	amidohydrolase
PMA3_RS16475	COG3618	amidohydrolase
PMA3_RS16480	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS16505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS16510	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS16515	COG0174	glutamine synthetase
PMA3_RS16520	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PMA3_RS16525	COG3842	ATPase activity
PMA3_RS16530	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS16535	COG1177	transmembrane transport
PMA3_RS16545	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PMA3_RS16555	COG5507	3-demethylubiquinone-9 3-methyltransferase
PMA3_RS16620	COG0174	glutamine synthetase
PMA3_RS16645	COG1620	l-lactate permease
PMA3_RS16650	COG2186	Transcriptional regulator
PMA3_RS16655	COG0277	FAD linked oxidase domain protein
PMA3_RS16660	COG0277	FAD linked oxidase domain protein
PMA3_RS16665	COG0247	lactate metabolic process
PMA3_RS16670	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PMA3_RS16675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PMA3_RS16680	COG0477	Major facilitator Superfamily
PMA3_RS16690	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PMA3_RS16740	COG0626	cystathionine gamma-synthase activity
PMA3_RS16745	COG0861	Integral membrane protein TerC family
PMA3_RS16765	COG0596	Alpha beta hydrolase
PMA3_RS16785	COG1063	alcohol dehydrogenase
PMA3_RS16790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMA3_RS16795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMA3_RS16805	COG2258	MOSC domain
PMA3_RS16810	COG0583	DNA-binding transcription factor activity
PMA3_RS16815	COG2070	2-Nitropropane dioxygenase
PMA3_RS16820	COG3038	cytochrome b561
PMA3_RS16825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMA3_RS16830	COG3162	membrane
PMA3_RS16835	COG0583	DNA-binding transcription factor activity
PMA3_RS16865	COG1764	response to oxidative stress
PMA3_RS16870	COG1764	response to oxidative stress
PMA3_RS16875	COG1846	Transcriptional regulator
PMA3_RS16880	COG0667	Aldo Keto reductase
PMA3_RS16905	COG1215	transferase activity, transferring glycosyl groups
PMA3_RS16940	COG1764	response to oxidative stress
PMA3_RS16970	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS16980	COG0583	DNA-binding transcription factor activity
PMA3_RS16990	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS17015	COG0251	oxidation-reduction process
PMA3_RS17065	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PMA3_RS17090	COG2369	cell adhesion
PMA3_RS17095	COG0579	oxidoreductase
PMA3_RS17100	COG0129	dihydroxy-acid dehydratase activity
PMA3_RS17130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMA3_RS17145	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PMA3_RS17150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PMA3_RS17155	COG3639	organic phosphonate transmembrane transporter activity
PMA3_RS17160	COG3639	organic phosphonate transmembrane transporter activity
PMA3_RS17220	COG0183	Belongs to the thiolase family
PMA3_RS17225	COG1511	domain protein
PMA3_RS17225	COG3264	Mechanosensitive ion channel
PMA3_RS17230	COG0450	alkyl hydroperoxide reductase
PMA3_RS17245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PMA3_RS17250	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS17255	COG0010	Belongs to the arginase family
PMA3_RS17275	COG1132	(ABC) transporter
PMA3_RS17280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PMA3_RS17300	COG2264	protein methyltransferase activity
PMA3_RS17310	COG1917	Cupin 2, conserved barrel domain protein
PMA3_RS17330	COG1063	alcohol dehydrogenase
PMA3_RS17375	COG2205	protein histidine kinase activity
PMA3_RS17385	COG3220	belongs to the UPF0276 family
PMA3_RS17395	COG4106	trans-aconitate 2-methyltransferase activity
PMA3_RS17400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PMA3_RS17405	COG0583	DNA-binding transcription factor activity
PMA3_RS17410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PMA3_RS17415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PMA3_RS17465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PMA3_RS17475	COG3706	GGDEF domain
PMA3_RS17510	COG0500	methyltransferase
PMA3_RS17525	COG4191	Histidine kinase
PMA3_RS17540	COG3852	Histidine kinase
PMA3_RS17635	COG0745	RESPONSE REGULATOR receiver
PMA3_RS17640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMA3_RS17670	COG0741	lytic transglycosylase activity
PMA3_RS17670	COG1196	nuclear chromosome segregation
PMA3_RS17670	COG0739	heme binding
PMA3_RS17680	COG1459	type II secretion system
PMA3_RS17690	COG0583	DNA-binding transcription factor activity
PMA3_RS17700	COG1335	isochorismatase
PMA3_RS17705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PMA3_RS17720	COG1917	Cupin 2, conserved barrel domain protein
PMA3_RS17720	COG4977	sequence-specific DNA binding
PMA3_RS17740	COG1741	Belongs to the pirin family
PMA3_RS17765	COG1250	3-hydroxyacyl-CoA dehydrogenase
PMA3_RS17770	COG1309	transcriptional regulator
PMA3_RS17785	COG0534	Mate efflux family protein
PMA3_RS17810	COG0583	DNA-binding transcription factor activity
PMA3_RS17835	COG5642	Protein of unknown function (DUF2384)
PMA3_RS17840	COG5654	RES domain protein
PMA3_RS17865	COG3842	ATPase activity
PMA3_RS17875	COG0395	ABC-type sugar transport system, permease component
PMA3_RS17880	COG3938	Belongs to the proline racemase family
PMA3_RS17885	COG5642	Protein of unknown function (DUF2384)
PMA3_RS17890	COG5654	RES domain protein
PMA3_RS17900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS17920	COG1177	transmembrane transport
PMA3_RS17925	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS17930	COG3842	ATPase activity
PMA3_RS17940	COG0583	DNA-binding transcription factor activity
PMA3_RS17945	COG2207	Transcriptional regulator
PMA3_RS17950	COG1733	regulation of RNA biosynthetic process
PMA3_RS17965	COG3064	Membrane
PMA3_RS18005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMA3_RS18015	COG2186	Transcriptional regulator
PMA3_RS18035	COG1192	Involved in chromosome partitioning
PMA3_RS18040	COG2358	TRAP transporter, solute receptor (TAXI family
PMA3_RS18055	COG1053	succinate dehydrogenase
PMA3_RS18075	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PMA3_RS18110	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS18115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PMA3_RS18130	COG1335	isochorismatase
PMA3_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS18140	COG3976	FMN-binding domain protein
PMA3_RS18140	COG1053	succinate dehydrogenase
PMA3_RS18140	COG0431	NADPH-dependent FMN reductase
PMA3_RS18150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PMA3_RS18155	COG2086	electron transfer activity
PMA3_RS18160	COG1053	succinate dehydrogenase
PMA3_RS18160	COG3976	FMN-binding domain protein
PMA3_RS18170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PMA3_RS18180	COG4580	involved in the transport of maltose and maltodextrins
PMA3_RS18185	COG0166	Belongs to the GPI family
PMA3_RS18190	COG1609	Transcriptional regulator
PMA3_RS18200	COG1172	Belongs to the binding-protein-dependent transport system permease family
PMA3_RS18205	COG1879	ABC-type sugar transport system periplasmic component
PMA3_RS18210	COG1072	(Pantothenic acid kinase))
PMA3_RS18220	COG2384	SAM-dependent methyltransferase
PMA3_RS18235	COG0596	Alpha beta hydrolase
PMA3_RS18240	COG3180	Ammonia monooxygenase
PMA3_RS18245	COG0583	DNA-binding transcription factor activity
PMA3_RS18270	COG1132	(ABC) transporter
PMA3_RS18300	COG0583	DNA-binding transcription factor activity
PMA3_RS18305	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PMA3_RS18310	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS18345	COG4773	Receptor
PMA3_RS18355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PMA3_RS18360	COG5000	phosphorelay sensor kinase activity
PMA3_RS18380	COG1733	regulation of RNA biosynthetic process
PMA3_RS18390	COG1309	transcriptional regulator
PMA3_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS18400	COG2267	carboxylic ester hydrolase activity
PMA3_RS18410	COG0596	Alpha beta hydrolase
PMA3_RS18465	COG2175	clavaminate synthase activity
PMA3_RS18480	COG2267	carboxylic ester hydrolase activity
PMA3_RS18490	COG2207	Transcriptional regulator
PMA3_RS18500	COG3300	MHYT domain
PMA3_RS18500	COG5001	Diguanylate cyclase
PMA3_RS18520	COG1802	Transcriptional regulator
PMA3_RS18525	COG1914	H( )-stimulated, divalent metal cation uptake system
PMA3_RS18530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PMA3_RS18535	COG4336	lyase activity
PMA3_RS18540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PMA3_RS18545	COG4770	biotin carboxylase activity
PMA3_RS18650	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS18655	COG0183	Belongs to the thiolase family
PMA3_RS18660	COG1250	3-hydroxyacyl-CoA dehydrogenase
PMA3_RS18680	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS18685	COG1024	Enoyl-CoA hydratase
PMA3_RS18690	COG1024	Enoyl-CoA hydratase
PMA3_RS18695	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS18705	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PMA3_RS18710	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS18715	COG1846	Transcriptional regulator
PMA3_RS18720	COG0411	ABC transporter
PMA3_RS18745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PMA3_RS18750	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS18755	COG2030	dehydratase
PMA3_RS18770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PMA3_RS18780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMA3_RS18790	COG2358	TRAP transporter, solute receptor (TAXI family
PMA3_RS18805	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS18820	COG2194	sulfuric ester hydrolase activity
PMA3_RS18835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMA3_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS18850	COG0596	Alpha beta hydrolase
PMA3_RS18855	COG1414	Transcriptional regulator
PMA3_RS18875	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS18905	COG0477	Major facilitator Superfamily
PMA3_RS18910	COG0154	amidase activity
PMA3_RS18935	COG0840	transmembrane signaling receptor activity
PMA3_RS18960	COG4974	Belongs to the 'phage' integrase family
PMA3_RS18975	COG3119	arylsulfatase activity
PMA3_RS18985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PMA3_RS18990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PMA3_RS18995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PMA3_RS19000	COG2828	Protein conserved in bacteria
PMA3_RS19025	COG1301	dicarboxylic acid transport
PMA3_RS19030	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS19035	COG0583	DNA-binding transcription factor activity
PMA3_RS19080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS19085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PMA3_RS19090	COG2814	Major facilitator Superfamily
PMA3_RS19140	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PMA3_RS19155	COG0583	DNA-binding transcription factor activity
PMA3_RS19165	COG2851	Citrate transporter
PMA3_RS19170	COG1301	dicarboxylic acid transport
PMA3_RS19175	COG2828	Protein conserved in bacteria
PMA3_RS19180	COG0583	DNA-binding transcription factor activity
PMA3_RS19185	COG1454	alcohol dehydrogenase
PMA3_RS19190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS19195	COG1757	Na H antiporter
PMA3_RS19200	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS19210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PMA3_RS19215	COG5383	Protein conserved in bacteria
PMA3_RS19220	COG0028	Belongs to the TPP enzyme family
PMA3_RS19225	COG1301	dicarboxylic acid transport
PMA3_RS19235	COG0583	DNA-binding transcription factor activity
PMA3_RS19255	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PMA3_RS19280	COG2271	Major facilitator Superfamily
PMA3_RS19295	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS19300	COG2721	sulfolactate sulfo-lyase activity
PMA3_RS19305	COG0583	DNA-binding transcription factor activity
PMA3_RS19315	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS19325	COG3938	Belongs to the proline racemase family
PMA3_RS19330	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS19335	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS19340	COG3448	diguanylate cyclase activity
PMA3_RS19340	COG4175	Glycine betaine
PMA3_RS19345	COG2113	Glycine betaine
PMA3_RS19355	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS19360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMA3_RS19365	COG1802	Transcriptional regulator
PMA3_RS19385	COG1764	response to oxidative stress
PMA3_RS19390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS19395	COG0697	spore germination
PMA3_RS19420	COG2211	Major facilitator Superfamily
PMA3_RS19430	COG0673	inositol 2-dehydrogenase activity
PMA3_RS19435	COG1609	Transcriptional regulator
PMA3_RS19440	COG0456	acetyltransferase
PMA3_RS19445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PMA3_RS19475	COG1335	isochorismatase
PMA3_RS19535	COG2920	part of a sulfur-relay system
PMA3_RS19540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PMA3_RS19545	COG0435	Glutathione S-transferase
PMA3_RS19550	COG1648	precorrin-2 dehydrogenase activity
PMA3_RS19550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PMA3_RS19555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PMA3_RS19560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMA3_RS19565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PMA3_RS19570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PMA3_RS19575	COG1674	ftsk spoiiie
PMA3_RS19580	COG0492	ferredoxin-NADP+ reductase activity
PMA3_RS19585	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PMA3_RS19590	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PMA3_RS19595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PMA3_RS19600	COG0542	response to heat
PMA3_RS19605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PMA3_RS19610	COG1278	Cold shock
PMA3_RS19630	COG0482	sulfurtransferase activity
PMA3_RS19635	COG2915	High frequency lysogenization protein hflD homolog
PMA3_RS19645	COG2850	peptidyl-arginine hydroxylation
PMA3_RS19650	COG2153	protein acetylation
PMA3_RS19665	COG0495	leucyl-tRNA aminoacylation
PMA3_RS19670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PMA3_RS19675	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PMA3_RS19680	COG0649	NAD binding
PMA3_RS19680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PMA3_RS19695	COG1034	ATP synthesis coupled electron transport
PMA3_RS19700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PMA3_RS19715	COG0713	ATP synthesis coupled electron transport
PMA3_RS19730	COG1007	ATP synthesis coupled electron transport
PMA3_RS19735	COG2944	sequence-specific DNA binding
PMA3_RS19785	COG0395	ABC-type sugar transport system, permease component
PMA3_RS19795	COG3842	ATPase activity
PMA3_RS19800	COG3842	ATPase activity
PMA3_RS19805	COG3284	Transcriptional regulator
PMA3_RS19810	COG0215	cysteine-tRNA ligase activity
PMA3_RS19815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMA3_RS19825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PMA3_RS19830	COG2814	Major facilitator Superfamily
PMA3_RS19835	COG1566	PFAM secretion protein HlyD family protein
PMA3_RS19845	COG1846	Transcriptional regulator
PMA3_RS19850	COG2911	Protein conserved in bacteria
PMA3_RS19855	COG0729	surface antigen
PMA3_RS19865	COG0708	Exodeoxyribonuclease III
PMA3_RS19870	COG0517	IMP dehydrogenase activity
PMA3_RS19890	COG0625	glutathione transferase activity
PMA3_RS19900	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PMA3_RS19905	COG0709	Synthesizes selenophosphate from selenide and ATP
PMA3_RS19940	COG2056	Na+-H+ antiporter family
PMA3_RS19945	COG0840	transmembrane signaling receptor activity
PMA3_RS19970	COG0720	synthase
PMA3_RS19975	COG2267	carboxylic ester hydrolase activity
PMA3_RS19980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PMA3_RS19985	COG0402	S-adenosylhomocysteine deaminase activity
PMA3_RS19990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PMA3_RS19995	COG2223	nitrite transmembrane transporter activity
PMA3_RS20000	COG4772	TonB-dependent receptor
PMA3_RS20010	COG1595	DNA-templated transcription, initiation
PMA3_RS20030	COG2814	Major facilitator Superfamily
PMA3_RS20055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PMA3_RS20075	COG1335	isochorismatase
PMA3_RS20085	COG0583	DNA-binding transcription factor activity
PMA3_RS20090	COG0656	L-ascorbic acid biosynthetic process
PMA3_RS20095	COG2205	protein histidine kinase activity
PMA3_RS20095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS20100	COG2197	response regulator
PMA3_RS20120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS20125	COG0577	efflux transmembrane transporter activity
PMA3_RS20125	COG1136	(ABC) transporter
PMA3_RS20175	COG3179	chitinase
PMA3_RS20185	COG0657	acetylesterase activity
PMA3_RS20200	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PMA3_RS20210	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS20215	COG3387	PFAM Glycoside hydrolase 15-related
PMA3_RS20225	COG4977	sequence-specific DNA binding
PMA3_RS20285	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PMA3_RS20290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMA3_RS20320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMA3_RS20325	COG3115	cell septum assembly
PMA3_RS20330	COG1196	nuclear chromosome segregation
PMA3_RS20355	COG0402	S-adenosylhomocysteine deaminase activity
PMA3_RS20360	COG1802	Transcriptional regulator
PMA3_RS20365	COG3135	benzoate transporter
PMA3_RS20370	COG3171	Protein conserved in bacteria
PMA3_RS20375	COG2027	D-alanyl-D-alanine carboxypeptidase
PMA3_RS20385	COG0116	Belongs to the methyltransferase superfamily
PMA3_RS20385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PMA3_RS20390	COG0167	dihydroorotate dehydrogenase activity
PMA3_RS20395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PMA3_RS20395	COG1116	anion transmembrane transporter activity
PMA3_RS20400	COG3707	response regulator
PMA3_RS20405	COG2223	nitrite transmembrane transporter activity
PMA3_RS20410	COG0515	serine threonine protein kinase
PMA3_RS20410	COG2815	serine threonine protein kinase
PMA3_RS20415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PMA3_RS20420	COG2146	nitrite reductase [NAD(P)H] activity
PMA3_RS20425	COG0243	molybdopterin cofactor binding
PMA3_RS20430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PMA3_RS20445	COG0668	transmembrane transport
PMA3_RS20460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PMA3_RS20475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PMA3_RS20480	COG2079	MmgE PrpD family protein
PMA3_RS20495	COG0372	Belongs to the citrate synthase family
PMA3_RS20505	COG1802	Transcriptional regulator
PMA3_RS20510	COG4067	protein conserved in archaea
PMA3_RS20510	COG0189	ligase activity
PMA3_RS20520	COG0189	ligase activity
PMA3_RS20525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PMA3_RS20530	COG0560	Phosphoserine phosphatase
PMA3_RS20540	COG1953	Uracil, thiamine, allantoin
PMA3_RS20550	COG0583	DNA-binding transcription factor activity
PMA3_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS20560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PMA3_RS20590	COG0393	Putative heavy-metal-binding
PMA3_RS20625	COG0582	viral genome integration into host DNA
PMA3_RS20690	COG0204	Acyl-transferase
PMA3_RS20695	COG0598	Magnesium transport protein CorA
PMA3_RS20700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PMA3_RS20700	COG0519	Catalyzes the synthesis of GMP from XMP
PMA3_RS20710	COG0183	Belongs to the thiolase family
PMA3_RS20730	COG2308	Evidence 4 Homologs of previously reported genes of
PMA3_RS20790	COG0745	RESPONSE REGULATOR receiver
PMA3_RS20795	COG2205	protein histidine kinase activity
PMA3_RS20800	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PMA3_RS20810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PMA3_RS20835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PMA3_RS20840	COG4221	oxidoreductase activity
PMA3_RS20845	COG1555	photosystem II stabilization
PMA3_RS20855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PMA3_RS20910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PMA3_RS20915	COG1091	dTDP-4-dehydrorhamnose reductase activity
PMA3_RS20935	COG0776	regulation of translation
PMA3_RS20950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PMA3_RS20955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PMA3_RS20960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PMA3_RS20970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PMA3_RS20980	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PMA3_RS20985	COG0402	S-adenosylhomocysteine deaminase activity
PMA3_RS20990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PMA3_RS20995	COG0546	phosphoglycolate phosphatase activity
PMA3_RS21000	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS21010	COG0477	Major facilitator Superfamily
PMA3_RS21055	COG2067	long-chain fatty acid transport protein
PMA3_RS21060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PMA3_RS21065	COG0569	domain protein
PMA3_RS21085	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PMA3_RS21095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PMA3_RS21105	COG1492	cobalamin metabolic process
PMA3_RS21120	COG0778	Nitroreductase
PMA3_RS21125	COG1797	cobyrinic acid a,c-diamide synthase activity
PMA3_RS21145	COG0791	NLP P60 protein
PMA3_RS21150	COG0791	NLP P60 protein
PMA3_RS21155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMA3_RS21160	COG0628	permease
PMA3_RS21170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PMA3_RS21175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PMA3_RS21195	COG1741	Belongs to the pirin family
PMA3_RS21205	COG0326	Molecular chaperone. Has ATPase activity
PMA3_RS21245	COG0045	succinate-CoA ligase (ADP-forming) activity
PMA3_RS21250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMA3_RS21265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PMA3_RS21270	COG1053	succinate dehydrogenase
PMA3_RS21275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PMA3_RS21280	COG2009	succinate dehydrogenase
PMA3_RS21290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMA3_RS21295	COG3162	membrane
PMA3_RS21300	COG2113	Glycine betaine
PMA3_RS21325	COG2853	Lipoprotein
PMA3_RS21330	COG2354	Protein conserved in bacteria
PMA3_RS21335	COG1309	transcriptional regulator
PMA3_RS21350	COG3960	tartronate-semialdehyde synthase activity
PMA3_RS21355	COG3622	Belongs to the hyi family
PMA3_RS21360	COG2084	Dehydrogenase
PMA3_RS21380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PMA3_RS21390	COG2814	Major facilitator Superfamily
PMA3_RS21395	COG1598	PFAM Uncharacterised protein family UPF0150
PMA3_RS21410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PMA3_RS21415	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PMA3_RS21420	COG3454	Phosphonate metabolism
PMA3_RS21425	COG4778	phosphonate C-P lyase system protein PhnL
PMA3_RS21430	COG4107	phosphonate C-P lyase system protein PhnK
PMA3_RS21435	COG3627	carbon phosphorus lyase activity
PMA3_RS21440	COG3626	phosphonate metabolism
PMA3_RS21450	COG3624	Phosphonate C-P lyase system protein PhnG
PMA3_RS21455	COG2188	Transcriptional regulator
PMA3_RS21460	COG3639	organic phosphonate transmembrane transporter activity
PMA3_RS21465	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PMA3_RS21470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PMA3_RS21485	COG3088	subunit of a heme lyase
PMA3_RS21495	COG1138	Cytochrome C-type biogenesis protein
PMA3_RS21500	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PMA3_RS21520	COG4133	protoheme IX ABC transporter activity
PMA3_RS21530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PMA3_RS21555	COG0835	chemotaxis
PMA3_RS21570	COG1192	Involved in chromosome partitioning
PMA3_RS21580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PMA3_RS21585	COG2201	protein-glutamate methylesterase activity
PMA3_RS21590	COG0643	Histidine kinase
PMA3_RS21590	COG0784	Response regulator, receiver
PMA3_RS21590	COG2198	Histidine kinase
PMA3_RS21595	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PMA3_RS21685	COG1580	Controls the rotational direction of flagella during chemotaxis
PMA3_RS21700	COG0745	RESPONSE REGULATOR receiver
PMA3_RS21720	COG1317	bacterial-type flagellum organization
PMA3_RS21735	COG1677	Flagellar hook-basal body complex protein FliE
PMA3_RS21765	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PMA3_RS21780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PMA3_RS21800	COG1706	bacterial-type flagellum-dependent cell motility
PMA3_RS21805	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PMA3_RS21815	COG4787	bacterial-type flagellum-dependent cell motility
PMA3_RS21830	COG2154	pterin-4-alpha-carbinolamine dehydratase
PMA3_RS21860	COG2944	sequence-specific DNA binding
PMA3_RS21865	COG2249	NAD(P)H dehydrogenase (quinone) activity
PMA3_RS21870	COG1113	amino acid transport
PMA3_RS21885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PMA3_RS21895	COG0009	L-threonylcarbamoyladenylate synthase
PMA3_RS21900	COG0613	PHP domain protein
PMA3_RS21905	COG2917	probably involved in intracellular septation
PMA3_RS21910	COG2350	Protein conserved in bacteria
PMA3_RS21915	COG0745	RESPONSE REGULATOR receiver
PMA3_RS21925	COG0642	Histidine kinase
PMA3_RS21930	COG0778	Nitroreductase
PMA3_RS21935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PMA3_RS21985	COG0514	ATP-dependent DNA helicase (RecQ)
PMA3_RS21995	COG2832	Protein of unknown function (DUF454)
PMA3_RS22050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMA3_RS22065	COG0697	spore germination
PMA3_RS22070	COG2996	Protein conserved in bacteria
PMA3_RS22105	COG0513	Belongs to the DEAD box helicase family
PMA3_RS22110	COG0668	transmembrane transport
PMA3_RS22135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PMA3_RS22160	COG1132	(ABC) transporter
PMA3_RS22165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PMA3_RS22175	COG2188	Transcriptional regulator
PMA3_RS22185	COG1643	Atp-dependent helicase
PMA3_RS22190	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PMA3_RS22200	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS22210	COG4948	Mandelate Racemase Muconate Lactonizing
PMA3_RS22215	COG3547	Transposase (IS116 IS110 IS902 family)
PMA3_RS22255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PMA3_RS22275	COG0542	response to heat
PMA3_RS22285	COG1984	allophanate hydrolase subunit 2
PMA3_RS22290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PMA3_RS22305	COG0121	glutamine amidotransferase
PMA3_RS22350	COG2983	Belongs to the UPF0260 family
PMA3_RS22365	COG3100	YcgL domain-containing protein
PMA3_RS22375	COG0174	glutamine synthetase
PMA3_RS22380	COG2807	transmembrane transport
PMA3_RS22420	COG0784	Response regulator, receiver
PMA3_RS22420	COG4191	Histidine kinase
PMA3_RS22430	COG4221	oxidoreductase activity
PMA3_RS22445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PMA3_RS22485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PMA3_RS22490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PMA3_RS22495	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PMA3_RS22500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMA3_RS22510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PMA3_RS22520	COG0425	Belongs to the sulfur carrier protein TusA family
PMA3_RS22525	COG4783	chaperone-mediated protein folding
PMA3_RS22530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMA3_RS22560	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PMA3_RS22605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PMA3_RS22625	COG1116	anion transmembrane transporter activity
PMA3_RS22640	COG0439	Biotin carboxylase
PMA3_RS22665	COG2267	carboxylic ester hydrolase activity
PMA3_RS22720	COG1653	transport
PMA3_RS22740	COG1621	beta-fructofuranosidase activity
PMA3_RS22755	COG4106	trans-aconitate 2-methyltransferase activity
PMA3_RS22780	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PMA3_RS22790	COG1454	alcohol dehydrogenase
PMA3_RS22810	COG0693	protein deglycase activity
PMA3_RS22815	COG0697	spore germination
PMA3_RS22850	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PMA3_RS22855	COG1704	LemA family
PMA3_RS22865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMA3_RS22910	COG2814	Major facilitator Superfamily
PMA3_RS22915	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS22935	COG0436	Aminotransferase
PMA3_RS22945	COG3265	gluconokinase activity
PMA3_RS22950	COG1609	Transcriptional regulator
PMA3_RS22975	COG0242	peptide deformylase activity
PMA3_RS22980	COG1295	ribonuclease BN
PMA3_RS22985	COG3237	CsbD-like
PMA3_RS22995	COG0318	PFAM AMP-dependent synthetase and ligase
PMA3_RS23010	COG2030	dehydratase
PMA3_RS23035	COG3530	Putative quorum-sensing-regulated virulence factor
PMA3_RS23045	COG3485	protocatechuate 3,4-dioxygenase
PMA3_RS23050	COG0800	Aldolase
PMA3_RS23065	COG1737	Transcriptional regulator
PMA3_RS23070	COG0676	glucose-6-phosphate 1-epimerase activity
PMA3_RS23085	COG0395	ABC-type sugar transport system, permease component
PMA3_RS23090	COG1175	transmembrane transport
PMA3_RS23095	COG1653	transport
PMA3_RS23130	COG1803	Methylglyoxal synthase
PMA3_RS23135	COG1595	DNA-templated transcription, initiation
PMA3_RS23140	COG3712	iron ion homeostasis
PMA3_RS23145	COG4771	TonB-dependent receptor
PMA3_RS23155	COG2832	Protein of unknown function (DUF454)
PMA3_RS23160	COG0840	transmembrane signaling receptor activity
PMA3_RS23165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PMA3_RS23175	COG0509	glycine decarboxylation via glycine cleavage system
PMA3_RS23180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PMA3_RS23180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PMA3_RS23185	COG1760	l-serine dehydratase
PMA3_RS23190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PMA3_RS23195	COG1278	Cold shock
PMA3_RS23205	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PMA3_RS23215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PMA3_RS23220	COG0602	queuosine metabolic process
PMA3_RS23225	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PMA3_RS23230	COG2885	chlorophyll binding
PMA3_RS23235	COG0823	Involved in the tonB-independent uptake of proteins
PMA3_RS23255	COG0824	Thioesterase
PMA3_RS23260	COG2255	four-way junction helicase activity
PMA3_RS23265	COG0632	four-way junction helicase activity
PMA3_RS23270	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PMA3_RS23275	COG0217	transcriptional regulatory protein
PMA3_RS23280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PMA3_RS23300	COG2900	Belongs to the SlyX family
PMA3_RS23315	COG0668	transmembrane transport
PMA3_RS23320	COG1666	GTP binding
PMA3_RS23330	COG4191	Histidine kinase
PMA3_RS23330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS23335	COG2096	Adenosyltransferase
PMA3_RS23350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PMA3_RS23355	COG0653	protein targeting
PMA3_RS23365	COG0433	COG0433 Predicted ATPase
PMA3_RS23380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMA3_RS23380	COG0438	transferase activity, transferring glycosyl groups
PMA3_RS23405	COG2925	Exonuclease
PMA3_RS23430	COG0714	Associated with various cellular activities
PMA3_RS23450	COG0469	pyruvate kinase activity
PMA3_RS23455	COG1024	Enoyl-CoA hydratase
PMA3_RS23460	COG0633	Ferredoxin
PMA3_RS23460	COG0543	2 iron, 2 sulfur cluster binding
PMA3_RS23470	COG4191	Histidine kinase
PMA3_RS23480	COG0477	Major facilitator Superfamily
PMA3_RS23505	COG2207	Transcriptional regulator
PMA3_RS23510	COG3842	ATPase activity
PMA3_RS23520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PMA3_RS23530	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS23540	COG0583	DNA-binding transcription factor activity
PMA3_RS23550	COG0583	DNA-binding transcription factor activity
PMA3_RS23575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PMA3_RS23580	COG0583	DNA-binding transcription factor activity
PMA3_RS23595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PMA3_RS23640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS23645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PMA3_RS23650	COG3642	lipopolysaccharide core region biosynthetic process
PMA3_RS23660	COG0642	Histidine kinase
PMA3_RS23670	COG0459	protein refolding
PMA3_RS23675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PMA3_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS23695	COG0489	protein tyrosine kinase activity
PMA3_RS23700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMA3_RS23700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMA3_RS23705	COG4657	Part of a membrane complex involved in electron transport
PMA3_RS23710	COG2878	Part of a membrane complex involved in electron transport
PMA3_RS23715	COG4658	electron transport chain
PMA3_RS23730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMA3_RS23740	COG2197	response regulator
PMA3_RS23750	COG0137	argininosuccinate synthase activity
PMA3_RS23760	COG0418	dihydroorotase activity
PMA3_RS23765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PMA3_RS23770	COG0450	alkyl hydroperoxide reductase
PMA3_RS23785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PMA3_RS23790	COG0243	molybdopterin cofactor binding
PMA3_RS23800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PMA3_RS23805	COG3842	ATPase activity
PMA3_RS23815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PMA3_RS23825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PMA3_RS23840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS23845	COG0765	amino acid transport
PMA3_RS23850	COG0765	amino acid transport
PMA3_RS23855	COG1126	abc transporter atp-binding protein
PMA3_RS23870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PMA3_RS23880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PMA3_RS23885	COG0583	DNA-binding transcription factor activity
PMA3_RS23895	COG1280	lysine exporter protein (LysE YggA)
PMA3_RS23900	COG0494	nUDIX hydrolase
PMA3_RS23910	COG3300	MHYT domain
PMA3_RS23910	COG5001	Diguanylate cyclase
PMA3_RS23920	COG1858	cytochrome C peroxidase
PMA3_RS23945	COG2246	polysaccharide biosynthetic process
PMA3_RS23960	COG2246	polysaccharide biosynthetic process
PMA3_RS23965	COG1113	amino acid transport
PMA3_RS24005	COG1695	Transcriptional regulator
PMA3_RS24010	COG2375	cellular response to nickel ion
PMA3_RS24020	COG4628	conserved protein (DUF2132)
PMA3_RS24060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PMA3_RS24085	COG2226	methyltransferase
PMA3_RS24090	COG0500	methyltransferase
PMA3_RS24095	COG0590	tRNA wobble adenosine to inosine editing
PMA3_RS24110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PMA3_RS24110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PMA3_RS24115	COG4580	involved in the transport of maltose and maltodextrins
PMA3_RS24120	COG0366	Alpha amylase catalytic
PMA3_RS24125	COG1263	PTS System
PMA3_RS24125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PMA3_RS24130	COG2188	Transcriptional regulator
PMA3_RS24140	COG0519	Catalyzes the synthesis of GMP from XMP
PMA3_RS24140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PMA3_RS24165	COG1570	exodeoxyribonuclease VII activity
PMA3_RS24170	COG0739	heme binding
PMA3_RS24180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PMA3_RS24190	COG0436	Aminotransferase
PMA3_RS24195	COG1160	GTP binding
PMA3_RS24210	COG0124	histidyl-tRNA synthetase
PMA3_RS24215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PMA3_RS24230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PMA3_RS24235	COG0105	UTP biosynthetic process
PMA3_RS24245	COG0633	Ferredoxin
PMA3_RS24250	COG0443	Heat shock 70 kDa protein
PMA3_RS24255	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PMA3_RS24260	COG0316	Belongs to the HesB IscA family
PMA3_RS24270	COG1104	cysteine desulfurase activity
PMA3_RS24280	COG1045	serine acetyltransferase
PMA3_RS24295	COG3134	Outer membrane lipoprotein
PMA3_RS24310	COG1862	Preprotein translocase
PMA3_RS24315	COG0343	queuine tRNA-ribosyltransferase activity
PMA3_RS24320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PMA3_RS24380	COG3383	formate dehydrogenase (NAD+) activity
PMA3_RS24395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMA3_RS24400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMA3_RS24405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMA3_RS24410	COG0745	RESPONSE REGULATOR receiver
PMA3_RS24430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS24450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PMA3_RS24455	COG1509	lysine 2,3-aminomutase activity
PMA3_RS24460	COG0625	glutathione transferase activity
PMA3_RS24485	COG2186	Transcriptional regulator
PMA3_RS24515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PMA3_RS24525	COG2814	Major facilitator Superfamily
PMA3_RS24540	COG0109	protoheme IX farnesyltransferase activity
PMA3_RS24550	COG1845	cytochrome c oxidase, subunit III
PMA3_RS24555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PMA3_RS24560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PMA3_RS24565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PMA3_RS24580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PMA3_RS24585	COG0315	cyclic pyranopterin monophosphate synthase activity
PMA3_RS24590	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PMA3_RS24600	COG3022	response to hydroperoxide
PMA3_RS24610	COG1215	transferase activity, transferring glycosyl groups
PMA3_RS24615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMA3_RS24620	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PMA3_RS24630	COG3420	alginic acid biosynthetic process
PMA3_RS24645	COG1696	Membrane protein involved in D-alanine export
PMA3_RS24660	COG0662	Cupin 2, conserved barrel domain protein
PMA3_RS24660	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PMA3_RS24690	COG0300	oxidoreductase activity
PMA3_RS24695	COG1566	PFAM secretion protein HlyD family protein
PMA3_RS24715	COG0583	DNA-binding transcription factor activity
PMA3_RS24725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMA3_RS24735	COG0697	spore germination
PMA3_RS24745	COG4774	siderophore transport
PMA3_RS24780	COG0583	DNA-binding transcription factor activity
PMA3_RS24785	COG1760	l-serine dehydratase
PMA3_RS24790	COG0814	amino acid
PMA3_RS24810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PMA3_RS24825	COG0179	Fumarylacetoacetate (FAA) hydrolase
PMA3_RS24830	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PMA3_RS24840	COG2197	response regulator
PMA3_RS24860	COG1028	Short-chain dehydrogenase reductase Sdr
PMA3_RS24875	COG1366	Belongs to the anti-sigma-factor antagonist family
PMA3_RS24895	COG0302	gtp cyclohydrolase
PMA3_RS24900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PMA3_RS24915	COG0765	amino acid transport
PMA3_RS24920	COG1126	abc transporter atp-binding protein
PMA3_RS24925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS24930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS24935	COG0492	ferredoxin-NADP+ reductase activity
PMA3_RS24940	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PMA3_RS24945	COG0438	transferase activity, transferring glycosyl groups
PMA3_RS24955	COG0386	Belongs to the glutathione peroxidase family
PMA3_RS24965	COG0280	phosphate acetyltransferase
PMA3_RS24965	COG0857	belongs to the CobB CobQ family
PMA3_RS24970	COG0204	Acyl-transferase
PMA3_RS25000	COG2274	protein secretion by the type I secretion system
PMA3_RS25005	COG1538	Outer membrane efflux protein
PMA3_RS25015	COG0175	sulfate reduction
PMA3_RS25025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PMA3_RS25030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PMA3_RS25035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PMA3_RS25040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PMA3_RS25045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PMA3_RS25065	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PMA3_RS25070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PMA3_RS25075	COG1127	ABC transporter
PMA3_RS25085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PMA3_RS25095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PMA3_RS25100	COG1137	ATPase activity
PMA3_RS25105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PMA3_RS25110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMA3_RS25120	COG1660	Displays ATPase and GTPase activities
PMA3_RS25155	COG0312	modulator of DNA gyrase
PMA3_RS25160	COG3028	Belongs to the UPF0307 family
PMA3_RS25165	COG0312	modulator of DNA gyrase
PMA3_RS25170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMA3_RS25185	COG1530	ribonuclease E activity
PMA3_RS25190	COG0424	maF-like protein
PMA3_RS25200	COG1792	Involved in formation and maintenance of cell shape
PMA3_RS25205	COG1077	Cell shape determining protein MreB Mrl
PMA3_RS25210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMA3_RS25215	COG0154	amidase activity
PMA3_RS25220	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMA3_RS25225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PMA3_RS25235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PMA3_RS25245	COG2721	sulfolactate sulfo-lyase activity
PMA3_RS25250	COG2271	Major facilitator Superfamily
PMA3_RS25260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMA3_RS25270	COG2186	Transcriptional regulator
PMA3_RS25275	COG4178	(ABC) transporter
PMA3_RS25280	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PMA3_RS25295	COG0747	negative chemotaxis
PMA3_RS25300	COG0747	negative chemotaxis
PMA3_RS25310	COG0747	negative chemotaxis
PMA3_RS25315	COG0601	transmembrane transport
PMA3_RS25320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMA3_RS25325	COG0444	Belongs to the ABC transporter superfamily
PMA3_RS25330	COG4608	Belongs to the ABC transporter superfamily
PMA3_RS25355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PMA3_RS25380	COG0019	diaminopimelate decarboxylase activity
PMA3_RS25395	COG3128	pkhd-type hydroxylase
PMA3_RS25400	COG4774	siderophore transport
PMA3_RS25410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PMA3_RS25415	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PMA3_RS25415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PMA3_RS25415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PMA3_RS25420	COG1105	Belongs to the carbohydrate kinase PfkB family
PMA3_RS25430	COG1609	Transcriptional regulator
PMA3_RS25435	COG0084	hydrolase, TatD family'
PMA3_RS25450	COG3023	N-Acetylmuramoyl-L-alanine amidase
PMA3_RS25470	COG1185	polyribonucleotide nucleotidyltransferase activity
PMA3_RS25475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PMA3_RS25480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PMA3_RS25485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PMA3_RS25490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PMA3_RS25495	COG0195	Participates in both transcription termination and antitermination
PMA3_RS25500	COG0779	Required for maturation of 30S ribosomal subunits
PMA3_RS25515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PMA3_RS25520	COG0149	triose-phosphate isomerase activity
PMA3_RS25525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMA3_RS25530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PMA3_RS25540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PMA3_RS25555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PMA3_RS25560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PMA3_RS25565	COG0505	Belongs to the CarA family
PMA3_RS25570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PMA3_RS25575	COG0484	heat shock protein binding
PMA3_RS25580	COG0443	Heat shock 70 kDa protein
PMA3_RS25585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PMA3_RS25590	COG0497	DNA recombination
PMA3_RS25595	COG0735	belongs to the Fur family
PMA3_RS25600	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PMA3_RS25605	COG2914	Belongs to the UPF0125 (RnfH) family
PMA3_RS25615	COG0733	neurotransmitter:sodium symporter activity
PMA3_RS25620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PMA3_RS25625	COG2186	Transcriptional regulator
PMA3_RS25630	COG1620	l-lactate permease
PMA3_RS25635	COG0247	lactate metabolic process
PMA3_RS25670	COG0582	viral genome integration into host DNA
PMA3_RS25695	COG4983	Phage plasmid primase, P4 family domain protein
PMA3_RS25780	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PMA3_RS25785	COG5002	protein histidine kinase activity
PMA3_RS25805	COG0840	transmembrane signaling receptor activity
PMA3_RS25825	COG0659	secondary active sulfate transmembrane transporter activity
PMA3_RS25835	COG0583	DNA-binding transcription factor activity
PMA3_RS25840	COG2249	NAD(P)H dehydrogenase (quinone) activity
PMA3_RS25855	COG0583	DNA-binding transcription factor activity
PMA3_RS25860	COG2249	NAD(P)H dehydrogenase (quinone) activity
PMA3_RS25890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PMA3_RS25895	COG1074	ATP-dependent DNA helicase activity
PMA3_RS25900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PMA3_RS25945	COG1309	transcriptional regulator
PMA3_RS26060	COG2207	Transcriptional regulator
PMA3_RS26115	COG1115	amino acid carrier protein
PMA3_RS26125	COG0583	DNA-binding transcription factor activity
PMA3_RS26135	COG0473	3-isopropylmalate dehydrogenase activity
PMA3_RS26135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PMA3_RS26140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PMA3_RS26145	COG0436	Aminotransferase
PMA3_RS26245	COG0840	transmembrane signaling receptor activity
PMA3_RS26255	COG2814	Major facilitator Superfamily
PMA3_RS26330	COG0726	polysaccharide deacetylase
PMA3_RS26345	COG0174	glutamine synthetase
PMA3_RS26350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS26355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PMA3_RS26360	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS26370	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS26380	COG1522	sequence-specific DNA binding
PMA3_RS26390	COG0583	DNA-binding transcription factor activity
PMA3_RS26395	COG0833	amino acid
PMA3_RS26400	COG0626	cystathionine gamma-synthase activity
PMA3_RS26415	COG1322	Protein conserved in bacteria
PMA3_RS26420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PMA3_RS26480	COG2354	Protein conserved in bacteria
PMA3_RS26485	COG0387	Pfam Sodium calcium exchanger
PMA3_RS26490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PMA3_RS26505	COG0604	alcohol dehydrogenase
PMA3_RS26525	COG2217	Heavy metal translocating P-type atpase
PMA3_RS26545	COG2951	lytic endotransglycosylase activity
PMA3_RS26550	COG1619	proteins homologs of microcin C7 resistance protein MccF
PMA3_RS26555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PMA3_RS26560	COG0321	lipoyl(octanoyl) transferase activity
PMA3_RS26565	COG2921	Belongs to the UPF0250 family
PMA3_RS26570	COG1686	Belongs to the peptidase S11 family
PMA3_RS26580	COG2951	lytic endotransglycosylase activity
PMA3_RS26585	COG0772	Belongs to the SEDS family
PMA3_RS26590	COG0768	penicillin binding
PMA3_RS26595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PMA3_RS26605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PMA3_RS26610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PMA3_RS26615	COG2094	Belongs to the DNA glycosylase MPG family
PMA3_RS26620	COG0586	Pfam SNARE associated Golgi protein
PMA3_RS26650	COG1346	cytolysis
PMA3_RS26670	COG0702	epimerase
PMA3_RS26685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PMA3_RS26690	COG3284	Transcriptional regulator
PMA3_RS26700	COG0531	amino acid
PMA3_RS26705	COG4303	Ethanolamine ammonia lyase large subunit
PMA3_RS26710	COG4302	ethanolamine ammonia-lyase activity
PMA3_RS26715	COG0456	acetyltransferase
PMA3_RS26720	COG0586	Pfam SNARE associated Golgi protein
PMA3_RS26725	COG3228	Belongs to the MtfA family
PMA3_RS26730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PMA3_RS26750	COG4983	Phage plasmid primase, P4 family domain protein
PMA3_RS26765	COG5377	YqaJ viral recombinase family
PMA3_RS26775	COG2003	Belongs to the UPF0758 family
PMA3_RS26795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMA3_RS26810	COG3586	endonuclease activity
PMA3_RS26850	COG3077	Addiction module antitoxin, RelB DinJ family
PMA3_RS26855	COG2026	Addiction module toxin, RelE StbE family
PMA3_RS26860	COG4676	Protein conserved in bacteria
PMA3_RS26865	COG5445	Predicted secreted protein (DUF2300)
PMA3_RS26880	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
PMA3_RS26885	COG4676	Protein conserved in bacteria
PMA3_RS26890	COG1722	exodeoxyribonuclease VII activity
PMA3_RS26895	COG0142	geranyltranstransferase activity
PMA3_RS26900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PMA3_RS26905	COG4206	TonB-dependent receptor
PMA3_RS26910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PMA3_RS26920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PMA3_RS26930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PMA3_RS26935	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PMA3_RS26940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMA3_RS26945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PMA3_RS26960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMA3_RS26960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMA3_RS26965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMA3_RS26975	COG2264	protein methyltransferase activity
PMA3_RS26980	COG3118	belongs to the thioredoxin family
PMA3_RS27010	COG3047	cAMP biosynthetic process
PMA3_RS27015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PMA3_RS27025	COG1201	RNA secondary structure unwinding
PMA3_RS27030	COG0668	transmembrane transport
PMA3_RS27035	COG2814	Major facilitator Superfamily
PMA3_RS27045	COG3568	Endonuclease Exonuclease Phosphatase
PMA3_RS27050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMA3_RS27055	COG0392	lysyltransferase activity
PMA3_RS27070	COG4753	response regulator
PMA3_RS27070	COG2207	Transcriptional regulator
PMA3_RS27075	COG1335	isochorismatase
PMA3_RS27085	COG1842	Phage shock protein A
PMA3_RS27095	COG3766	membrane
PMA3_RS27105	COG0754	glutathionylspermidine amidase activity
PMA3_RS27110	COG1944	ATP diphosphatase activity
PMA3_RS27115	COG0629	single-stranded DNA binding
PMA3_RS27120	COG2814	Major facilitator Superfamily
PMA3_RS27125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PMA3_RS27130	COG2193	ferroxidase activity
PMA3_RS27140	COG0203	ribosomal protein L17
PMA3_RS27145	COG0202	RNA polymerase activity
PMA3_RS27150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PMA3_RS27155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PMA3_RS27160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PMA3_RS27170	COG0200	Binds to the 23S rRNA
PMA3_RS27175	COG1841	ribosomal large subunit assembly
PMA3_RS27180	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PMA3_RS27185	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PMA3_RS27190	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PMA3_RS27195	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PMA3_RS27200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMA3_RS27205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PMA3_RS27210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PMA3_RS27215	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PMA3_RS27220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PMA3_RS27225	COG0255	Belongs to the universal ribosomal protein uL29 family
PMA3_RS27230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PMA3_RS27235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PMA3_RS27240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMA3_RS27245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMA3_RS27250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PMA3_RS27255	COG0089	rRNA binding
PMA3_RS27260	COG0088	Forms part of the polypeptide exit tunnel
PMA3_RS27265	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PMA3_RS27270	COG0051	transcription antitermination factor activity, RNA binding
PMA3_RS27275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PMA3_RS27280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PMA3_RS27285	COG0049	tRNA binding
PMA3_RS27290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PMA3_RS27295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMA3_RS27300	COG0085	RNA polymerase activity
PMA3_RS27305	COG0222	ribosome binding
PMA3_RS27310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PMA3_RS27315	COG0081	regulation of translation
PMA3_RS27320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PMA3_RS27360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PMA3_RS27395	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PMA3_RS27400	COG0739	heme binding
PMA3_RS27405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PMA3_RS27410	COG0316	Belongs to the HesB IscA family
PMA3_RS27415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PMA3_RS27420	COG1981	membrane
PMA3_RS27435	COG4221	oxidoreductase activity
PMA3_RS27440	COG0537	adenosine 5'-monophosphoramidase activity
PMA3_RS27445	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PMA3_RS27450	COG1765	OsmC-like protein
PMA3_RS27465	COG0134	indole-3-glycerol-phosphate synthase activity
PMA3_RS27470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PMA3_RS27475	COG0512	Glutamine amidotransferase of anthranilate synthase
PMA3_RS27485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PMA3_RS27490	COG0546	phosphoglycolate phosphatase activity
PMA3_RS27495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PMA3_RS27505	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS27515	COG3842	ATPase activity
PMA3_RS27520	COG2197	response regulator
PMA3_RS27535	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PMA3_RS27540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PMA3_RS27545	COG3178	'Phosphotransferase
PMA3_RS27550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PMA3_RS27555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PMA3_RS27560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PMA3_RS27565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PMA3_RS27570	COG2967	ApaG domain
PMA3_RS27575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PMA3_RS27580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMA3_RS27585	COG2766	serine protein kinase
PMA3_RS27590	COG2718	Belongs to the UPF0229 family
PMA3_RS27595	COG2719	SpoVR family
PMA3_RS27600	COG0617	tRNA 3'-terminal CCA addition
PMA3_RS27610	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PMA3_RS27615	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PMA3_RS27620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PMA3_RS27625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PMA3_RS27630	COG0358	DNA primase activity
PMA3_RS27635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PMA3_RS27660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PMA3_RS27690	COG4993	Dehydrogenase
PMA3_RS27705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMA3_RS27710	COG1025	Belongs to the peptidase M16 family
PMA3_RS27715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PMA3_RS27720	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PMA3_RS27730	COG0535	radical SAM domain protein
PMA3_RS27745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PMA3_RS27750	COG0583	DNA-binding transcription factor activity
PMA3_RS27755	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS27760	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS27765	COG1960	acyl-CoA dehydrogenase activity
PMA3_RS27780	COG1073	alpha beta
PMA3_RS27780	COG2226	methyltransferase
PMA3_RS27785	COG0156	8-amino-7-oxononanoate synthase activity
PMA3_RS27790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PMA3_RS27795	COG1040	competence protein
PMA3_RS27805	COG3585	molybdate ion transport
PMA3_RS27805	COG2005	Transcriptional regulator
PMA3_RS27815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PMA3_RS27830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PMA3_RS27835	COG2204	response regulator
PMA3_RS27850	COG1595	DNA-templated transcription, initiation
PMA3_RS27855	COG3712	iron ion homeostasis
PMA3_RS27860	COG4774	siderophore transport
PMA3_RS27875	COG0625	glutathione transferase activity
PMA3_RS27890	COG0189	ligase activity
PMA3_RS27890	COG4067	protein conserved in archaea
PMA3_RS27905	COG0204	Acyl-transferase
PMA3_RS27920	COG1063	alcohol dehydrogenase
PMA3_RS27935	COG1063	alcohol dehydrogenase
PMA3_RS27965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PMA3_RS27985	COG1017	nitric oxide dioxygenase activity
PMA3_RS27985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PMA3_RS27990	COG4638	Rieske (2fe-2S)
PMA3_RS28005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PMA3_RS28010	COG2181	nitrate reductase activity
PMA3_RS28010	COG0247	lactate metabolic process
PMA3_RS28015	COG1902	pentaerythritol trinitrate reductase activity
PMA3_RS28015	COG0446	pyridine nucleotide-disulphide oxidoreductase
PMA3_RS28040	COG2304	oxidoreductase activity
PMA3_RS28060	COG3246	L-lysine catabolic process to acetate
PMA3_RS28065	COG1250	3-hydroxyacyl-CoA dehydrogenase
PMA3_RS28090	COG1760	l-serine dehydratase
PMA3_RS28100	COG4176	ABC-type proline glycine betaine transport system permease component
PMA3_RS28105	COG3448	diguanylate cyclase activity
PMA3_RS28105	COG4175	Glycine betaine
PMA3_RS28115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PMA3_RS28120	COG1309	transcriptional regulator
PMA3_RS28125	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS28130	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PMA3_RS28140	COG0312	modulator of DNA gyrase
PMA3_RS28145	COG0477	Major facilitator Superfamily
PMA3_RS28150	COG0513	Belongs to the DEAD box helicase family
PMA3_RS28155	COG2081	HI0933 family
PMA3_RS28160	COG1289	transmembrane transporter activity
PMA3_RS28165	COG2153	protein acetylation
PMA3_RS28175	COG1451	nucleotide metabolic process
PMA3_RS28205	COG0126	phosphoglycerate kinase activity
PMA3_RS28210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PMA3_RS28220	COG4106	trans-aconitate 2-methyltransferase activity
PMA3_RS28225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PMA3_RS28230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMA3_RS28235	COG1422	Protein of unknown function (DUF1090)
PMA3_RS28260	COG2814	Major facilitator Superfamily
PMA3_RS28265	COG2116	formate transmembrane transporter activity
PMA3_RS28275	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PMA3_RS28280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PMA3_RS28290	COG0513	Belongs to the DEAD box helicase family
PMA3_RS28295	COG2353	YceI-like domain
PMA3_RS28300	COG3038	cytochrome b561
PMA3_RS28315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PMA3_RS28320	COG1272	protein, Hemolysin III
PMA3_RS28360	COG3052	prosthetic group binding
PMA3_RS28365	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PMA3_RS28395	COG2198	Histidine kinase
PMA3_RS28395	COG0643	Histidine kinase
PMA3_RS28395	COG0784	Response regulator, receiver
PMA3_RS28425	COG0189	ligase activity
PMA3_RS28435	COG1678	Uncharacterized ACR, COG1678
PMA3_RS28440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PMA3_RS28445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PMA3_RS28450	COG0540	Belongs to the ATCase OTCase family
PMA3_RS28455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PMA3_RS28465	COG0791	NLP P60 protein
PMA3_RS28490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PMA3_RS28495	COG2813	Specifically methylates the guanine in position
PMA3_RS28495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PMA3_RS28505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PMA3_RS28510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PMA3_RS28520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PMA3_RS28525	COG2022	thiamine diphosphate biosynthetic process
PMA3_RS28535	COG2363	Small membrane protein
PMA3_RS28540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PMA3_RS28550	COG2177	Part of the ABC transporter FtsEX involved in
PMA3_RS28555	COG2884	Cell division ATP-binding protein ftsE
PMA3_RS28560	COG0552	protein localization to endoplasmic reticulum
PMA3_RS28565	COG0612	Peptidase, M16
PMA3_RS28570	COG0612	Peptidase, M16
PMA3_RS28575	COG0742	ribosomal rna small subunit methyltransferase
PMA3_RS28590	COG0429	hydrolase of the alpha beta-hydrolase fold
PMA3_RS28620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PMA3_RS28625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PMA3_RS28630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PMA3_RS28640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PMA3_RS28650	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PMA3_RS28655	COG2814	Major facilitator Superfamily
PMA3_RS28660	COG0129	dihydroxy-acid dehydratase activity
PMA3_RS28680	COG1823	symporter activity
PMA3_RS28695	COG1160	GTP binding
PMA3_RS28710	COG1840	ABC-type Fe3 transport system, periplasmic component
PMA3_RS28715	COG1178	ABC-type Fe3 transport system permease component
PMA3_RS28720	COG3842	ATPase activity
PMA3_RS28725	COG0583	DNA-binding transcription factor activity
PMA3_RS28735	COG0789	Transcriptional regulator
PMA3_RS28740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PMA3_RS28745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PMA3_RS28750	COG0730	response to heat
PMA3_RS28760	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
PMA3_RS28765	COG0494	nUDIX hydrolase
PMA3_RS28780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PMA3_RS28785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PMA3_RS28790	COG3204	pilus organization
PMA3_RS28795	COG3204	pilus organization
PMA3_RS28800	COG0179	Fumarylacetoacetate (FAA) hydrolase
PMA3_RS28805	COG0277	FAD linked oxidase domain protein
PMA3_RS28810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PMA3_RS28820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS28825	COG1683	Conserved Protein
PMA3_RS28865	COG1177	transmembrane transport
PMA3_RS28870	COG1176	ABC-type spermidine putrescine transport system, permease component I
PMA3_RS28875	COG3842	ATPase activity
PMA3_RS28895	COG0174	glutamine synthetase
PMA3_RS28905	COG0174	glutamine synthetase
PMA3_RS28920	COG1116	anion transmembrane transporter activity
PMA3_RS28925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PMA3_RS28935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PMA3_RS28940	COG0431	NADPH-dependent FMN reductase
PMA3_RS28945	COG0450	alkyl hydroperoxide reductase
PMA3_RS28965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PMA3_RS28965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PMA3_RS28980	COG1522	sequence-specific DNA binding
PMA3_RS28990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PMA3_RS29000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PMA3_RS29000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PMA3_RS29005	COG0509	glycine decarboxylation via glycine cleavage system
PMA3_RS29010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PMA3_RS29015	COG1178	ABC-type Fe3 transport system permease component
PMA3_RS29025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMA3_RS29030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PMA3_RS29035	COG0006	proline dipeptidase activity
PMA3_RS29040	COG3079	Belongs to the UPF0149 family
PMA3_RS29060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PMA3_RS29085	COG2271	Major facilitator Superfamily
PMA3_RS29100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PMA3_RS29115	COG2186	Transcriptional regulator
PMA3_RS29120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS29125	COG0765	amino acid transport
PMA3_RS29130	COG0765	amino acid transport
PMA3_RS29135	COG1126	abc transporter atp-binding protein
PMA3_RS29140	COG0248	Ppx GppA phosphatase
PMA3_RS29145	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PMA3_RS29155	COG0586	Pfam SNARE associated Golgi protein
PMA3_RS29165	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PMA3_RS29170	COG1671	Belongs to the UPF0178 family
PMA3_RS29175	COG0672	)-iron permease
PMA3_RS29180	COG1280	lysine exporter protein (LysE YggA)
PMA3_RS29190	COG0488	(ABC) transporter
PMA3_RS29215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PMA3_RS29235	COG0181	hydroxymethylbilane synthase activity
PMA3_RS29245	COG0165	Argininosuccinate lyase
PMA3_RS29250	COG0625	glutathione transferase activity
PMA3_RS29270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PMA3_RS29275	COG1965	Belongs to the frataxin family
PMA3_RS29285	COG0019	diaminopimelate decarboxylase activity
PMA3_RS29290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PMA3_RS29300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PMA3_RS29305	COG1011	Hydrolase
PMA3_RS29315	COG0432	Pfam Uncharacterised protein family UPF0047
PMA3_RS29320	COG0004	ammonium transporteR
PMA3_RS29325	COG0347	Belongs to the P(II) protein family
PMA3_RS29340	COG3093	addiction module antidote protein HigA
PMA3_RS29345	COG0606	chelatase, subunit chli
PMA3_RS29350	COG1404	Belongs to the peptidase S8 family
PMA3_RS29355	COG0464	growth
PMA3_RS29360	COG0606	chelatase, subunit chli
PMA3_RS29370	COG0583	DNA-binding transcription factor activity
PMA3_RS29375	COG0534	Mate efflux family protein
PMA3_RS29390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PMA3_RS29395	COG0427	acetyl-CoA hydrolase
PMA3_RS29410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PMA3_RS29415	COG0251	oxidation-reduction process
PMA3_RS29420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS29435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PMA3_RS29445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PMA3_RS29450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMA3_RS29465	COG1012	belongs to the aldehyde dehydrogenase family
PMA3_RS29485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PMA3_RS29490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PMA3_RS29495	COG0747	negative chemotaxis
PMA3_RS29500	COG2003	Belongs to the UPF0758 family
PMA3_RS29505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PMA3_RS29510	COG0756	dUTP diphosphatase activity
PMA3_RS29515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMA3_RS29520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PMA3_RS29525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMA3_RS29530	COG0708	Exodeoxyribonuclease III
PMA3_RS29535	COG0786	glutamate:sodium symporter activity
PMA3_RS29545	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PMA3_RS29550	COG1561	YicC-like family, N-terminal region
PMA3_RS29555	COG0194	GDP metabolic process
PMA3_RS29560	COG1758	RNA polymerase activity
PMA3_RS29565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMA3_RS29590	COG0848	biopolymer transport protein
PMA3_RS29600	COG0583	DNA-binding transcription factor activity
PMA3_RS29605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PMA3_RS29650	COG3161	chorismate lyase activity
PMA3_RS29655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PMA3_RS29675	COG1253	flavin adenine dinucleotide binding
PMA3_RS29680	COG0739	heme binding
PMA3_RS29690	COG0704	Plays a role in the regulation of phosphate uptake
PMA3_RS29695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PMA3_RS29700	COG0573	inorganic phosphate transmembrane transporter activity
PMA3_RS29715	COG0477	Major facilitator Superfamily
PMA3_RS29720	COG1607	acyl-coa hydrolase
PMA3_RS29755	COG0583	DNA-binding transcription factor activity
PMA3_RS29760	COG1027	Aspartate ammonia-lyase
PMA3_RS29765	COG1115	amino acid carrier protein
PMA3_RS29770	COG0252	asparaginase activity
PMA3_RS29815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PMA3_RS29820	COG0765	amino acid transport
PMA3_RS29825	COG5016	pyruvate
PMA3_RS29825	COG0511	ligase activity, forming carbon-carbon bonds
PMA3_RS29830	COG0439	Biotin carboxylase
PMA3_RS29835	COG0583	DNA-binding transcription factor activity
PMA3_RS29850	COG0210	DNA helicase
PMA3_RS29865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PMA3_RS29865	COG4651	solute:proton antiporter activity
PMA3_RS29870	COG1607	acyl-coa hydrolase
PMA3_RS29875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PMA3_RS29885	COG0523	cobalamin synthesis protein
PMA3_RS29910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMA3_RS29910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMA3_RS29920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMA3_RS29925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PMA3_RS29930	COG2217	Heavy metal translocating P-type atpase
PMA3_RS29955	COG1280	lysine exporter protein (LysE YggA)
PMA3_RS29970	COG1017	nitric oxide dioxygenase activity
PMA3_RS29970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PMA3_RS29975	COG0625	glutathione transferase activity
PMA3_RS29980	COG0583	DNA-binding transcription factor activity
PMA3_RS29985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PMA3_RS29990	COG1349	DNA-binding transcription factor activity
PMA3_RS29995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PMA3_RS30000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PMA3_RS30005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PMA3_RS30010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PMA3_RS30015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PMA3_RS30020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMA3_RS30025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PMA3_RS30035	COG0356	it plays a direct role in the translocation of protons across the membrane
PMA3_RS30040	COG3312	ion transport
PMA3_RS30045	COG1475	DNA binding
PMA3_RS30050	COG1192	Involved in chromosome partitioning
PMA3_RS30055	COG0357	Ribosomal RNA small subunit methyltransferase G
PMA3_RS30060	COG0445	tRNA wobble uridine modification
PMA3_RS30080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PMA3_RS30085	COG0706	membrane insertase activity
PMA3_RS30090	COG0594	ribonuclease P activity
PMA3_RS30095	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMA3_RS30100	COG0592	DNA-directed DNA polymerase activity
PMA3_RS30105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMA3_RS30110	COG0187	DNA topoisomerase II activity
PMA3_RS30120	COG5002	protein histidine kinase activity
PMA3_RS30130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PMA3_RS30135	COG0751	glycine-tRNA ligase activity
PMA3_RS30140	COG0752	glycyl-tRNA synthetase alpha subunit
PMA3_RS30145	COG2818	Glycosylase
PMA3_RS30160	COG0569	domain protein
PMA3_RS30165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PMA3_RS30170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PMA3_RS30175	COG0242	peptide deformylase activity
PMA3_RS30185	COG0758	DNA mediated transformation
PMA3_RS30190	COG0009	L-threonylcarbamoyladenylate synthase
PMA3_RS30200	COG0408	coproporphyrinogen oxidase activity
PMA3_RS30205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMA3_RS30220	COG3119	arylsulfatase activity
PMA3_RS30245	COG2851	Citrate transporter
PMA3_RS30250	COG0861	Integral membrane protein TerC family
PMA3_RS30255	COG1283	sodium-dependent phosphate transmembrane transporter activity
PMA3_RS30260	COG0612	Peptidase, M16
PMA3_RS30270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PMA3_RS30275	COG1127	ABC transporter
PMA3_RS30290	COG0700	Nucleoside recognition
PMA3_RS30295	COG1301	dicarboxylic acid transport
PMA3_RS30315	COG2204	response regulator
PMA3_RS30320	COG5002	protein histidine kinase activity
PMA3_RS30325	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PMA3_RS30330	COG3023	N-Acetylmuramoyl-L-alanine amidase
PMA3_RS30345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PMA3_RS30360	COG0218	Necessary for normal cell division and for the maintenance of normal septation