locus-tag	class	description
CRN80_RS00030	COG3012	SEC-C Motif Domain Protein
CRN80_RS00040	COG0653	protein targeting
CRN80_RS00045	COG2366	antibiotic biosynthetic process
CRN80_RS00060	COG1793	dna ligase
CRN80_RS00090	COG1201	RNA secondary structure unwinding
CRN80_RS00105	COG0717	Belongs to the dCTP deaminase family
CRN80_RS00110	COG1278	Cold shock
CRN80_RS00125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CRN80_RS00130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CRN80_RS00135	COG0585	pseudouridine synthase activity
CRN80_RS00140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CRN80_RS00145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CRN80_RS00150	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CRN80_RS00170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CRN80_RS00180	COG0148	phosphopyruvate hydratase activity
CRN80_RS00185	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CRN80_RS00190	COG0504	CTP synthase activity
CRN80_RS00195	COG0037	tRNA processing
CRN80_RS00200	COG0825	malonyl-CoA metabolic process
CRN80_RS00205	COG0587	DNA-directed DNA polymerase activity
CRN80_RS00210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CRN80_RS00215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN80_RS00220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN80_RS00225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CRN80_RS00230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN80_RS00250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CRN80_RS00260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CRN80_RS00265	COG0233	cytoplasmic translational termination
CRN80_RS00270	COG0528	UMP kinase activity
CRN80_RS00275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CRN80_RS00280	COG0052	Belongs to the universal ribosomal protein uS2 family
CRN80_RS00285	COG0024	Methionine aminopeptidase
CRN80_RS00290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CRN80_RS00295	COG0436	Aminotransferase
CRN80_RS00320	COG2828	Protein conserved in bacteria
CRN80_RS00335	COG2197	response regulator
CRN80_RS00345	COG2951	lytic endotransglycosylase activity
CRN80_RS00420	COG1196	nuclear chromosome segregation
CRN80_RS00530	COG2856	Zn peptidase
CRN80_RS00575	COG2197	response regulator
CRN80_RS00585	COG3237	CsbD-like
CRN80_RS00665	COG0145	ligase activity
CRN80_RS00670	COG4647	ligase activity
CRN80_RS00675	COG0145	ligase activity
CRN80_RS00690	COG0523	cobalamin synthesis protein
CRN80_RS00700	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS00705	COG4221	oxidoreductase activity
CRN80_RS00710	COG2267	carboxylic ester hydrolase activity
CRN80_RS00750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CRN80_RS00765	COG1063	alcohol dehydrogenase
CRN80_RS00780	COG1917	Cupin 2, conserved barrel domain protein
CRN80_RS00780	COG2169	Transcriptional regulator
CRN80_RS00795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS00800	COG0531	amino acid
CRN80_RS00815	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CRN80_RS00820	COG5001	Diguanylate cyclase
CRN80_RS00820	COG3300	MHYT domain
CRN80_RS00910	COG1393	Belongs to the ArsC family
CRN80_RS00915	COG2171	N-acyltransferase activity
CRN80_RS00920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRN80_RS00925	COG2166	iron-sulfur cluster assembly
CRN80_RS00935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CRN80_RS00940	COG1215	transferase activity, transferring glycosyl groups
CRN80_RS00950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRN80_RS00955	COG2226	methyltransferase
CRN80_RS00970	COG2937	Belongs to the GPAT DAPAT family
CRN80_RS00990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN80_RS00995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS01020	COG0742	ribosomal rna small subunit methyltransferase
CRN80_RS01035	COG1801	Protein of unknown function DUF72
CRN80_RS01050	COG0563	adenylate kinase activity
CRN80_RS01055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CRN80_RS01070	COG2885	chlorophyll binding
CRN80_RS01100	COG1073	alpha beta
CRN80_RS01115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CRN80_RS01125	COG3706	GGDEF domain
CRN80_RS01125	COG4251	negative regulation of phosphorylation
CRN80_RS01125	COG2203	Gaf domain
CRN80_RS01125	COG5001	Diguanylate cyclase
CRN80_RS01130	COG2201	protein-glutamate methylesterase activity
CRN80_RS01145	COG0457	Tetratricopeptide repeat
CRN80_RS01145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CRN80_RS01170	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CRN80_RS01180	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS01185	COG3158	transport of potassium into the cell
CRN80_RS01190	COG3657	addiction module killer protein
CRN80_RS01200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CRN80_RS01220	COG4807	Protein conserved in bacteria
CRN80_RS01240	COG0583	DNA-binding transcription factor activity
CRN80_RS01255	COG3148	PFAM DTW domain containing protein
CRN80_RS01270	COG2137	regulation of response to DNA damage stimulus
CRN80_RS01275	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CRN80_RS01280	COG1546	Belongs to the CinA family
CRN80_RS01290	COG3179	chitinase
CRN80_RS01510	COG2135	peptidase activity
CRN80_RS01525	COG3179	chitinase
CRN80_RS01680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN80_RS01715	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CRN80_RS01735	COG0582	viral genome integration into host DNA
CRN80_RS01750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CRN80_RS01755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CRN80_RS01760	COG0489	protein tyrosine kinase activity
CRN80_RS01765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN80_RS01765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN80_RS01770	COG2878	Part of a membrane complex involved in electron transport
CRN80_RS01775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CRN80_RS01785	COG2197	response regulator
CRN80_RS01790	COG0137	argininosuccinate synthase activity
CRN80_RS01810	COG0418	dihydroorotase activity
CRN80_RS01815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN80_RS01825	COG0450	alkyl hydroperoxide reductase
CRN80_RS01840	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CRN80_RS01845	COG0243	molybdopterin cofactor binding
CRN80_RS01855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CRN80_RS01860	COG3842	ATPase activity
CRN80_RS01875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CRN80_RS01885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CRN80_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS01905	COG0765	amino acid transport
CRN80_RS01910	COG0765	amino acid transport
CRN80_RS01915	COG1126	abc transporter atp-binding protein
CRN80_RS01940	COG4191	Histidine kinase
CRN80_RS01955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CRN80_RS01970	COG2076	Multidrug Resistance protein
CRN80_RS01995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CRN80_RS02000	COG0583	DNA-binding transcription factor activity
CRN80_RS02010	COG0494	nUDIX hydrolase
CRN80_RS02020	COG2204	response regulator
CRN80_RS02030	COG1858	cytochrome C peroxidase
CRN80_RS02035	COG3290	protein histidine kinase activity
CRN80_RS02045	COG0254	rRNA binding
CRN80_RS02060	COG0069	glutamate synthase activity
CRN80_RS02100	COG1113	amino acid transport
CRN80_RS02155	COG1695	Transcriptional regulator
CRN80_RS02160	COG2375	cellular response to nickel ion
CRN80_RS02180	COG4628	conserved protein (DUF2132)
CRN80_RS02185	COG4206	TonB-dependent receptor
CRN80_RS02215	COG0523	cobalamin synthesis protein
CRN80_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS02255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CRN80_RS02270	COG2226	methyltransferase
CRN80_RS02275	COG0500	methyltransferase
CRN80_RS02280	COG0590	tRNA wobble adenosine to inosine editing
CRN80_RS02295	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CRN80_RS02300	COG1381	Involved in DNA repair and RecF pathway recombination
CRN80_RS02305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CRN80_RS02310	COG0571	ribonuclease III activity
CRN80_RS02315	COG0681	Belongs to the peptidase S26 family
CRN80_RS02320	COG0481	GTPase activity
CRN80_RS02325	COG0795	lipopolysaccharide-transporting ATPase activity
CRN80_RS02330	COG0795	lipopolysaccharide-transporting ATPase activity
CRN80_RS02335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CRN80_RS02350	COG0525	valine-tRNA ligase activity
CRN80_RS02355	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CRN80_RS02365	COG3081	Nucleoid-associated protein
CRN80_RS02370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CRN80_RS02405	COG1595	DNA-templated transcription, initiation
CRN80_RS02410	COG3712	iron ion homeostasis
CRN80_RS02415	COG4772	TonB-dependent receptor
CRN80_RS02425	COG0583	DNA-binding transcription factor activity
CRN80_RS02430	COG0477	Major facilitator Superfamily
CRN80_RS02440	COG0583	DNA-binding transcription factor activity
CRN80_RS02445	COG1760	l-serine dehydratase
CRN80_RS02450	COG0814	amino acid
CRN80_RS02470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CRN80_RS02490	COG0179	Fumarylacetoacetate (FAA) hydrolase
CRN80_RS02495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CRN80_RS02510	COG4774	siderophore transport
CRN80_RS02520	COG2827	Endonuclease containing a URI domain
CRN80_RS02535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS02535	COG2205	protein histidine kinase activity
CRN80_RS02555	COG3539	Fimbrial protein
CRN80_RS02565	COG3121	Chaperone
CRN80_RS02570	COG3188	usher protein
CRN80_RS02585	COG2807	transmembrane transport
CRN80_RS02590	COG2186	Transcriptional regulator
CRN80_RS02595	COG1126	abc transporter atp-binding protein
CRN80_RS02600	COG0765	amino acid transport
CRN80_RS02605	COG4597	amino acid ABC transporter
CRN80_RS02610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS02620	COG0513	Belongs to the DEAD box helicase family
CRN80_RS02625	COG3209	COG3209 Rhs family protein
CRN80_RS02645	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CRN80_RS02650	COG0315	cyclic pyranopterin monophosphate synthase activity
CRN80_RS02660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CRN80_RS02710	COG3022	response to hydroperoxide
CRN80_RS02720	COG1215	transferase activity, transferring glycosyl groups
CRN80_RS02730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS02735	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CRN80_RS02745	COG3420	alginic acid biosynthetic process
CRN80_RS02765	COG1696	Membrane protein involved in D-alanine export
CRN80_RS02780	COG0662	Cupin 2, conserved barrel domain protein
CRN80_RS02780	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CRN80_RS02795	COG0300	oxidoreductase activity
CRN80_RS02805	COG0477	Major facilitator Superfamily
CRN80_RS02825	COG1566	PFAM secretion protein HlyD family protein
CRN80_RS02845	COG0583	DNA-binding transcription factor activity
CRN80_RS02850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN80_RS02855	COG0835	chemotaxis
CRN80_RS02855	COG0784	Response regulator, receiver
CRN80_RS02900	COG5002	protein histidine kinase activity
CRN80_RS02910	COG3706	GGDEF domain
CRN80_RS02910	COG5001	Diguanylate cyclase
CRN80_RS02910	COG2203	Gaf domain
CRN80_RS02910	COG4251	negative regulation of phosphorylation
CRN80_RS02920	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CRN80_RS02925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CRN80_RS02940	COG1181	Belongs to the D-alanine--D-alanine ligase family
CRN80_RS02945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CRN80_RS02950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CRN80_RS02955	COG0772	Belongs to the SEDS family
CRN80_RS02960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CRN80_RS02965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRN80_RS02970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CRN80_RS02975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CRN80_RS02990	COG0275	rRNA processing
CRN80_RS02995	COG2001	Belongs to the MraZ family
CRN80_RS03015	COG0792	nuclease activity
CRN80_RS03020	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CRN80_RS03025	COG2823	Periplasmic or secreted lipoprotein
CRN80_RS03030	COG2885	chlorophyll binding
CRN80_RS03035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN80_RS03045	COG2995	paraquat-inducible protein a
CRN80_RS03050	COG3008	intermembrane lipid transfer
CRN80_RS03060	COG2909	trisaccharide binding
CRN80_RS03075	COG0318	PFAM AMP-dependent synthetase and ligase
CRN80_RS03085	COG1280	lysine exporter protein (LysE YggA)
CRN80_RS03090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN80_RS03095	COG2813	Specifically methylates the guanine in position
CRN80_RS03100	COG2119	membrane
CRN80_RS03105	COG0501	Belongs to the peptidase M48B family
CRN80_RS03110	COG2135	peptidase activity
CRN80_RS03170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CRN80_RS03175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CRN80_RS03185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN80_RS03190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CRN80_RS03195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CRN80_RS03200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CRN80_RS03220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CRN80_RS03225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CRN80_RS03230	COG1127	ABC transporter
CRN80_RS03240	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CRN80_RS03250	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CRN80_RS03255	COG1137	ATPase activity
CRN80_RS03260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CRN80_RS03275	COG1660	Displays ATPase and GTPase activities
CRN80_RS03310	COG0312	modulator of DNA gyrase
CRN80_RS03315	COG3028	Belongs to the UPF0307 family
CRN80_RS03320	COG0312	modulator of DNA gyrase
CRN80_RS03325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRN80_RS03335	COG1530	ribonuclease E activity
CRN80_RS03340	COG0424	maF-like protein
CRN80_RS03350	COG1792	Involved in formation and maintenance of cell shape
CRN80_RS03355	COG1077	Cell shape determining protein MreB Mrl
CRN80_RS03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CRN80_RS03365	COG0154	amidase activity
CRN80_RS03370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CRN80_RS03375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CRN80_RS03385	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN80_RS03395	COG2721	sulfolactate sulfo-lyase activity
CRN80_RS03400	COG2271	Major facilitator Superfamily
CRN80_RS03410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN80_RS03420	COG2186	Transcriptional regulator
CRN80_RS03425	COG2969	positive regulation of protein catabolic process
CRN80_RS03430	COG0625	glutathione transferase activity
CRN80_RS03435	COG2857	Cytochrome c1
CRN80_RS03440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CRN80_RS03445	COG0723	plastoquinol--plastocyanin reductase activity
CRN80_RS03450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CRN80_RS03455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CRN80_RS03460	COG0667	Aldo Keto reductase
CRN80_RS03465	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS03475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CRN80_RS03480	COG0180	Tryptophanyl-tRNA synthetase
CRN80_RS03505	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CRN80_RS03525	COG0747	negative chemotaxis
CRN80_RS03530	COG0747	negative chemotaxis
CRN80_RS03535	COG0747	negative chemotaxis
CRN80_RS03545	COG0747	negative chemotaxis
CRN80_RS03550	COG0601	transmembrane transport
CRN80_RS03555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN80_RS03560	COG0444	Belongs to the ABC transporter superfamily
CRN80_RS03565	COG4608	Belongs to the ABC transporter superfamily
CRN80_RS03580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CRN80_RS03605	COG0019	diaminopimelate decarboxylase activity
CRN80_RS03615	COG3128	pkhd-type hydroxylase
CRN80_RS03620	COG4774	siderophore transport
CRN80_RS03625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CRN80_RS03635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN80_RS03635	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CRN80_RS03635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN80_RS03640	COG1105	Belongs to the carbohydrate kinase PfkB family
CRN80_RS03650	COG1609	Transcriptional regulator
CRN80_RS03655	COG0084	hydrolase, TatD family'
CRN80_RS03675	COG3023	N-Acetylmuramoyl-L-alanine amidase
CRN80_RS03715	COG0237	dephospho-CoA kinase activity
CRN80_RS03720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CRN80_RS03745	COG1252	NADH dehydrogenase
CRN80_RS03755	COG2894	cell division
CRN80_RS03780	COG0305	Participates in initiation and elongation during chromosome replication
CRN80_RS03800	COG3081	Nucleoid-associated protein
CRN80_RS03850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRN80_RS03860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRN80_RS03870	COG0431	NADPH-dependent FMN reductase
CRN80_RS03880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CRN80_RS03885	COG0640	Transcriptional regulator
CRN80_RS03975	COG0463	Glycosyl transferase, family 2
CRN80_RS04040	COG0789	Transcriptional regulator
CRN80_RS04115	COG1074	ATP-dependent DNA helicase activity
CRN80_RS04180	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN80_RS04185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS04245	COG1815	bacterial-type flagellum-dependent cell motility
CRN80_RS04275	COG1230	cation diffusion facilitator family transporter
CRN80_RS04340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CRN80_RS04365	COG0542	response to heat
CRN80_RS04390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS04405	COG4966	pilus assembly protein PilW
CRN80_RS04420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CRN80_RS04425	COG1047	Peptidyl-prolyl cis-trans
CRN80_RS04430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CRN80_RS04435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CRN80_RS04440	COG0196	riboflavin kinase activity
CRN80_RS04455	COG0268	Binds directly to 16S ribosomal RNA
CRN80_RS04470	COG0857	belongs to the CobB CobQ family
CRN80_RS04470	COG0280	phosphate acetyltransferase
CRN80_RS04475	COG0204	Acyl-transferase
CRN80_RS04485	COG0175	sulfate reduction
CRN80_RS04505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN80_RS04520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CRN80_RS04525	COG1090	epimerase
CRN80_RS04530	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CRN80_RS04545	COG0789	Transcriptional regulator
CRN80_RS04550	COG0415	Belongs to the DNA photolyase family
CRN80_RS04560	COG4221	oxidoreductase activity
CRN80_RS04575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CRN80_RS04595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CRN80_RS04600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CRN80_RS04610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CRN80_RS04615	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CRN80_RS04625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CRN80_RS04630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CRN80_RS04640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CRN80_RS04645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CRN80_RS04650	COG0193	aminoacyl-tRNA hydrolase activity
CRN80_RS04675	COG4669	(LipO)protein
CRN80_RS04715	COG4792	protein secretion
CRN80_RS04725	COG4794	Type iii secretion
CRN80_RS04785	COG0405	Gamma-glutamyltransferase
CRN80_RS04800	COG1181	Belongs to the D-alanine--D-alanine ligase family
CRN80_RS04815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CRN80_RS04865	COG2610	gluconate transmembrane transporter activity
CRN80_RS04880	COG0477	Major facilitator Superfamily
CRN80_RS04915	COG0288	reversible hydration of carbon dioxide
CRN80_RS04925	COG0456	acetyltransferase
CRN80_RS04950	COG3008	intermembrane lipid transfer
CRN80_RS04955	COG2995	paraquat-inducible protein a
CRN80_RS04960	COG2995	paraquat-inducible protein a
CRN80_RS05010	COG2233	PERMEase
CRN80_RS05015	COG1309	transcriptional regulator
CRN80_RS05035	COG0387	Pfam Sodium calcium exchanger
CRN80_RS05040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CRN80_RS05045	COG0477	Major facilitator Superfamily
CRN80_RS05055	COG0583	DNA-binding transcription factor activity
CRN80_RS05060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CRN80_RS05065	COG0604	alcohol dehydrogenase
CRN80_RS05075	COG2814	Major facilitator Superfamily
CRN80_RS05080	COG2217	Heavy metal translocating P-type atpase
CRN80_RS05090	COG2217	Heavy metal translocating P-type atpase
CRN80_RS05110	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS05145	COG4964	Belongs to the GSP D family
CRN80_RS05225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CRN80_RS05235	COG4953	penicillin-binding protein 1C
CRN80_RS05245	COG2373	Large extracellular alpha-helical protein
CRN80_RS05250	COG0534	Mate efflux family protein
CRN80_RS05255	COG1166	arginine decarboxylase activity
CRN80_RS05260	COG0023	Translation Initiation Factor
CRN80_RS05285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CRN80_RS05300	COG2264	protein methyltransferase activity
CRN80_RS05310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN80_RS05320	COG0138	bifunctional purine biosynthesis protein purh
CRN80_RS05325	COG0151	Belongs to the GarS family
CRN80_RS05340	COG2095	MarC family integral membrane protein
CRN80_RS05365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRN80_RS05385	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CRN80_RS05415	COG0683	leucine binding
CRN80_RS05430	COG0411	ABC transporter
CRN80_RS05440	COG0829	nickel cation binding
CRN80_RS05445	COG0831	urea catabolic process
CRN80_RS05460	COG0832	Belongs to the urease beta subunit family
CRN80_RS05465	COG0804	urea catabolic process
CRN80_RS05470	COG0484	heat shock protein binding
CRN80_RS05480	COG0443	Heat shock 70 kDa protein
CRN80_RS05515	COG0697	spore germination
CRN80_RS05520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CRN80_RS05530	COG2982	Protein involved in outer membrane biogenesis
CRN80_RS05540	COG1309	transcriptional regulator
CRN80_RS05545	COG0791	NLP P60 protein
CRN80_RS05550	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CRN80_RS05555	COG0830	nickel cation binding
CRN80_RS05560	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CRN80_RS05580	COG4221	oxidoreductase activity
CRN80_RS05615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS05620	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS05625	COG0583	DNA-binding transcription factor activity
CRN80_RS05630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CRN80_RS05635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CRN80_RS05660	COG2307	Protein conserved in bacteria
CRN80_RS05660	COG2308	Evidence 4 Homologs of previously reported genes of
CRN80_RS05690	COG1032	radical SAM domain protein
CRN80_RS05695	COG0305	Participates in initiation and elongation during chromosome replication
CRN80_RS05700	COG0359	binds to the 23S rRNA
CRN80_RS05710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CRN80_RS05715	COG0360	Binds together with S18 to 16S ribosomal RNA
CRN80_RS05720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRN80_RS05725	COG0557	exoribonuclease II activity
CRN80_RS05740	COG1840	ABC-type Fe3 transport system, periplasmic component
CRN80_RS05745	COG1178	ABC-type Fe3 transport system permease component
CRN80_RS05750	COG0840	transmembrane signaling receptor activity
CRN80_RS05755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CRN80_RS05760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CRN80_RS05765	COG0330	HflC and HflK could
CRN80_RS05770	COG0330	HflC and HflK could
CRN80_RS05775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CRN80_RS05780	COG1923	regulation of RNA biosynthetic process
CRN80_RS05785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CRN80_RS05790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CRN80_RS05795	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRN80_RS05800	COG0802	atpase or kinase
CRN80_RS05805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CRN80_RS05805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CRN80_RS05815	COG2860	membrane
CRN80_RS05820	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CRN80_RS05825	COG1162	GTPase activity
CRN80_RS05850	COG0688	phosphatidylethanolamine metabolic process
CRN80_RS05855	COG3830	Belongs to the UPF0237 family
CRN80_RS05855	COG0560	Phosphoserine phosphatase
CRN80_RS05885	COG3150	esterase
CRN80_RS05895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CRN80_RS05905	COG0494	nUDIX hydrolase
CRN80_RS05915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CRN80_RS05920	COG1538	Outer membrane efflux protein
CRN80_RS05925	COG1519	Transferase
CRN80_RS05945	COG0667	Aldo Keto reductase
CRN80_RS05955	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CRN80_RS05955	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CRN80_RS05970	COG1132	(ABC) transporter
CRN80_RS05980	COG1215	transferase activity, transferring glycosyl groups
CRN80_RS05985	COG0438	transferase activity, transferring glycosyl groups
CRN80_RS06000	COG2192	nodulation
CRN80_RS06015	COG4772	TonB-dependent receptor
CRN80_RS06020	COG0515	serine threonine protein kinase
CRN80_RS06040	COG0438	transferase activity, transferring glycosyl groups
CRN80_RS06045	COG0859	PFAM glycosyl transferase family 9
CRN80_RS06050	COG0859	PFAM glycosyl transferase family 9
CRN80_RS06055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CRN80_RS06080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CRN80_RS06085	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CRN80_RS06110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRN80_RS06115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CRN80_RS06115	COG0506	proline dehydrogenase activity
CRN80_RS06115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CRN80_RS06120	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS06140	COG3263	regulation of cellular component size
CRN80_RS06145	COG1196	nuclear chromosome segregation
CRN80_RS06145	COG3264	Mechanosensitive ion channel
CRN80_RS06150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CRN80_RS06165	COG3118	belongs to the thioredoxin family
CRN80_RS06180	COG1192	Involved in chromosome partitioning
CRN80_RS06195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRN80_RS06200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRN80_RS06210	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CRN80_RS06225	COG2986	histidine ammonia-lyase
CRN80_RS06250	COG2226	methyltransferase
CRN80_RS06260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN80_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS06275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN80_RS06290	COG0583	DNA-binding transcription factor activity
CRN80_RS06295	COG2814	Major facilitator Superfamily
CRN80_RS06300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CRN80_RS06305	COG0493	'glutamate synthase
CRN80_RS06310	COG0070	glutamate synthase
CRN80_RS06310	COG0069	glutamate synthase activity
CRN80_RS06310	COG0067	glutamate synthase
CRN80_RS06325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CRN80_RS06330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CRN80_RS06360	COG0281	malic enzyme
CRN80_RS06370	COG0254	rRNA binding
CRN80_RS06375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CRN80_RS06380	COG0018	arginyl-trna synthetase
CRN80_RS06390	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CRN80_RS06395	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CRN80_RS06420	COG1309	transcriptional regulator
CRN80_RS06440	COG2226	methyltransferase
CRN80_RS06450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CRN80_RS06455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CRN80_RS06460	COG0140	phosphoribosyl-ATP diphosphatase activity
CRN80_RS06465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRN80_RS06470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRN80_RS06485	COG0840	transmembrane signaling receptor activity
CRN80_RS06490	COG0840	transmembrane signaling receptor activity
CRN80_RS06495	COG1126	abc transporter atp-binding protein
CRN80_RS06500	COG0765	amino acid transport
CRN80_RS06510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS06515	COG2943	transferase activity, transferring hexosyl groups
CRN80_RS06520	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CRN80_RS06525	COG1490	D-aminoacyl-tRNA deacylase activity
CRN80_RS06530	COG0596	Alpha beta hydrolase
CRN80_RS06545	COG1228	amidohydrolase
CRN80_RS06550	COG1113	amino acid transport
CRN80_RS06555	COG2986	histidine ammonia-lyase
CRN80_RS06560	COG2986	histidine ammonia-lyase
CRN80_RS06565	COG4175	Glycine betaine
CRN80_RS06565	COG0517	IMP dehydrogenase activity
CRN80_RS06570	COG4176	ABC-type proline glycine betaine transport system permease component
CRN80_RS06580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CRN80_RS06585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CRN80_RS06600	COG2188	Transcriptional regulator
CRN80_RS06605	COG0402	S-adenosylhomocysteine deaminase activity
CRN80_RS06620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CRN80_RS06625	COG0058	SHG alpha-glucan phosphorylase activity
CRN80_RS06635	COG1217	gtp-binding protein TYPA
CRN80_RS06640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN80_RS06640	COG0301	tRNA thio-modification
CRN80_RS06660	COG3852	Histidine kinase
CRN80_RS06685	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CRN80_RS06695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN80_RS06700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CRN80_RS06705	COG4942	peptidase
CRN80_RS06710	COG0793	Belongs to the peptidase S41A family
CRN80_RS06715	COG2861	carbohydrate metabolic process
CRN80_RS06725	COG0107	imidazoleglycerol-phosphate synthase activity
CRN80_RS06730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CRN80_RS06740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CRN80_RS06745	COG0131	Imidazoleglycerol-phosphate dehydratase
CRN80_RS06760	COG1194	a g-specific adenine glycosylase
CRN80_RS06765	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CRN80_RS06780	COG4670	ketone body catabolic process
CRN80_RS06860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CRN80_RS06865	COG0473	3-isopropylmalate dehydrogenase activity
CRN80_RS06865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CRN80_RS06870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CRN80_RS06885	COG2070	2-Nitropropane dioxygenase
CRN80_RS06900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS06905	COG2814	Major facilitator Superfamily
CRN80_RS06910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS06915	COG2814	Major facilitator Superfamily
CRN80_RS06920	COG0583	DNA-binding transcription factor activity
CRN80_RS06940	COG2957	Belongs to the agmatine deiminase family
CRN80_RS06945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CRN80_RS06985	COG1218	3'(2'),5'-bisphosphate nucleotidase
CRN80_RS06990	COG0494	nUDIX hydrolase
CRN80_RS06995	COG1011	Hydrolase
CRN80_RS07000	COG1652	LysM domain
CRN80_RS07005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CRN80_RS07010	COG0243	molybdopterin cofactor binding
CRN80_RS07025	COG0514	ATP-dependent DNA helicase (RecQ)
CRN80_RS07040	COG2184	nucleotidyltransferase activity
CRN80_RS07060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CRN80_RS07065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CRN80_RS07075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CRN80_RS07080	COG2199	diguanylate cyclase activity
CRN80_RS07080	COG2200	EAL domain
CRN80_RS07080	COG3287	FIST C domain
CRN80_RS07085	COG0189	ligase activity
CRN80_RS07085	COG4067	protein conserved in archaea
CRN80_RS07090	COG0189	ligase activity
CRN80_RS07115	COG2183	response to ionizing radiation
CRN80_RS07125	COG2918	glutathione biosynthetic process
CRN80_RS07135	COG4521	taurine ABC transporter
CRN80_RS07140	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CRN80_RS07145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN80_RS07150	COG2175	clavaminate synthase activity
CRN80_RS07155	COG0667	Aldo Keto reductase
CRN80_RS07160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CRN80_RS07165	COG1045	serine acetyltransferase
CRN80_RS07170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CRN80_RS07175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS07180	COG0765	amino acid transport
CRN80_RS07185	COG1126	abc transporter atp-binding protein
CRN80_RS07215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CRN80_RS07220	COG2011	ABC-type metal ion transport system permease component
CRN80_RS07240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN80_RS07260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS07265	COG1126	abc transporter atp-binding protein
CRN80_RS07270	COG0765	amino acid transport
CRN80_RS07275	COG0765	amino acid transport
CRN80_RS07315	COG0583	DNA-binding transcription factor activity
CRN80_RS07320	COG2807	transmembrane transport
CRN80_RS07325	COG4771	TonB-dependent receptor
CRN80_RS07365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRN80_RS07370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN80_RS07400	COG2351	hydroxyisourate hydrolase activity
CRN80_RS07415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CRN80_RS07420	COG4208	sulfate ABC transporter
CRN80_RS07430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CRN80_RS07450	COG2199	diguanylate cyclase activity
CRN80_RS07460	COG0745	RESPONSE REGULATOR receiver
CRN80_RS07465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CRN80_RS07470	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS07485	COG5002	protein histidine kinase activity
CRN80_RS07490	COG0745	RESPONSE REGULATOR receiver
CRN80_RS07515	COG1280	lysine exporter protein (LysE YggA)
CRN80_RS07530	COG2304	oxidoreductase activity
CRN80_RS07535	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CRN80_RS07615	COG1215	transferase activity, transferring glycosyl groups
CRN80_RS07620	COG1649	PFAM Uncharacterised BCR, COG1649
CRN80_RS07620	COG0726	polysaccharide deacetylase
CRN80_RS07625	COG0457	Tetratricopeptide repeat
CRN80_RS07630	COG5339	Protein conserved in bacteria
CRN80_RS07645	COG1566	PFAM secretion protein HlyD family protein
CRN80_RS07655	COG1289	transmembrane transporter activity
CRN80_RS07705	COG4774	siderophore transport
CRN80_RS07715	COG1595	DNA-templated transcription, initiation
CRN80_RS07745	COG2175	clavaminate synthase activity
CRN80_RS07750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS07755	COG2274	protein secretion by the type I secretion system
CRN80_RS07775	COG5001	Diguanylate cyclase
CRN80_RS07775	COG3300	MHYT domain
CRN80_RS07785	COG1802	Transcriptional regulator
CRN80_RS07805	COG0840	transmembrane signaling receptor activity
CRN80_RS07850	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS07855	COG0583	DNA-binding transcription factor activity
CRN80_RS07875	COG0427	acetyl-CoA hydrolase
CRN80_RS07905	COG2851	Citrate transporter
CRN80_RS07910	COG0861	Integral membrane protein TerC family
CRN80_RS07920	COG1283	sodium-dependent phosphate transmembrane transporter activity
CRN80_RS07925	COG0612	Peptidase, M16
CRN80_RS07935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CRN80_RS07940	COG1127	ABC transporter
CRN80_RS07960	COG0700	Nucleoside recognition
CRN80_RS07965	COG1301	dicarboxylic acid transport
CRN80_RS07975	COG5487	UPF0391 membrane protein
CRN80_RS07985	COG2204	response regulator
CRN80_RS07990	COG5002	protein histidine kinase activity
CRN80_RS07995	COG3023	N-Acetylmuramoyl-L-alanine amidase
CRN80_RS08010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CRN80_RS08025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CRN80_RS08045	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CRN80_RS08050	COG0735	belongs to the Fur family
CRN80_RS08055	COG1121	(ABC) transporter
CRN80_RS08060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN80_RS08075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CRN80_RS08080	COG2011	ABC-type metal ion transport system permease component
CRN80_RS08095	COG0109	protoheme IX farnesyltransferase activity
CRN80_RS08125	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CRN80_RS08130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CRN80_RS08135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRN80_RS08145	COG0659	secondary active sulfate transmembrane transporter activity
CRN80_RS08185	COG0339	signal peptide processing
CRN80_RS08190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CRN80_RS08215	COG1764	response to oxidative stress
CRN80_RS08220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS08230	COG3360	Dodecin
CRN80_RS08250	COG0159	tryptophan synthase activity
CRN80_RS08260	COG2271	Major facilitator Superfamily
CRN80_RS08265	COG4948	Mandelate Racemase Muconate Lactonizing
CRN80_RS08270	COG0800	Aldolase
CRN80_RS08275	COG3734	2-keto-3-deoxy-galactonokinase
CRN80_RS08285	COG0583	DNA-binding transcription factor activity
CRN80_RS08290	COG3119	arylsulfatase activity
CRN80_RS08305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRN80_RS08310	COG0408	coproporphyrinogen oxidase activity
CRN80_RS08320	COG0009	L-threonylcarbamoyladenylate synthase
CRN80_RS08325	COG0758	DNA mediated transformation
CRN80_RS08335	COG0242	peptide deformylase activity
CRN80_RS08340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CRN80_RS08345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CRN80_RS08350	COG0569	domain protein
CRN80_RS08365	COG2818	Glycosylase
CRN80_RS08370	COG0752	glycyl-tRNA synthetase alpha subunit
CRN80_RS08375	COG0751	glycine-tRNA ligase activity
CRN80_RS08380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CRN80_RS08390	COG5002	protein histidine kinase activity
CRN80_RS08395	COG0745	RESPONSE REGULATOR receiver
CRN80_RS08410	COG0426	domain, Protein
CRN80_RS08410	COG1773	rubredoxin
CRN80_RS08430	COG3290	protein histidine kinase activity
CRN80_RS08440	COG3422	double-strand break repair
CRN80_RS08520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CRN80_RS08535	COG0210	DNA helicase
CRN80_RS08665	COG0463	Glycosyl transferase, family 2
CRN80_RS08715	COG2194	sulfuric ester hydrolase activity
CRN80_RS08790	COG0187	DNA topoisomerase II activity
CRN80_RS08795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CRN80_RS08800	COG0592	DNA-directed DNA polymerase activity
CRN80_RS08805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CRN80_RS08810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CRN80_RS08815	COG0594	ribonuclease P activity
CRN80_RS08820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CRN80_RS08825	COG0706	membrane insertase activity
CRN80_RS08830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CRN80_RS08840	COG3712	iron ion homeostasis
CRN80_RS08845	COG1595	DNA-templated transcription, initiation
CRN80_RS08850	COG0445	tRNA wobble uridine modification
CRN80_RS08855	COG0357	Ribosomal RNA small subunit methyltransferase G
CRN80_RS08860	COG1192	Involved in chromosome partitioning
CRN80_RS08865	COG1475	DNA binding
CRN80_RS08870	COG3312	ion transport
CRN80_RS08875	COG0356	it plays a direct role in the translocation of protons across the membrane
CRN80_RS08885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CRN80_RS08890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CRN80_RS08895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CRN80_RS08900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CRN80_RS08905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CRN80_RS08910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CRN80_RS08915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CRN80_RS08920	COG1349	DNA-binding transcription factor activity
CRN80_RS08925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CRN80_RS08930	COG4589	Belongs to the CDS family
CRN80_RS08945	COG2453	phosphatase
CRN80_RS08945	COG0671	phosphoesterase, PA-phosphatase related
CRN80_RS08950	COG2267	carboxylic ester hydrolase activity
CRN80_RS08955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CRN80_RS08975	COG2217	Heavy metal translocating P-type atpase
CRN80_RS08985	COG3220	belongs to the UPF0276 family
CRN80_RS08995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CRN80_RS09000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN80_RS09010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CRN80_RS09030	COG1121	(ABC) transporter
CRN80_RS09035	COG1469	GTP cyclohydrolase I activity
CRN80_RS09040	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRN80_RS09065	COG0523	cobalamin synthesis protein
CRN80_RS09075	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CRN80_RS09080	COG1607	acyl-coa hydrolase
CRN80_RS09085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CRN80_RS09085	COG4651	solute:proton antiporter activity
CRN80_RS09105	COG5001	Diguanylate cyclase
CRN80_RS09105	COG3300	MHYT domain
CRN80_RS09125	COG0583	DNA-binding transcription factor activity
CRN80_RS09130	COG0439	Biotin carboxylase
CRN80_RS09135	COG5016	pyruvate
CRN80_RS09135	COG0511	ligase activity, forming carbon-carbon bonds
CRN80_RS09160	COG0765	amino acid transport
CRN80_RS09165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS09220	COG0252	asparaginase activity
CRN80_RS09225	COG1115	amino acid carrier protein
CRN80_RS09265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRN80_RS09275	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS09290	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS09295	COG1414	Transcriptional regulator
CRN80_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS09315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN80_RS09330	COG1027	Aspartate ammonia-lyase
CRN80_RS09335	COG0583	DNA-binding transcription factor activity
CRN80_RS09370	COG1607	acyl-coa hydrolase
CRN80_RS09380	COG0477	Major facilitator Superfamily
CRN80_RS09400	COG0573	inorganic phosphate transmembrane transporter activity
CRN80_RS09405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CRN80_RS09410	COG0704	Plays a role in the regulation of phosphate uptake
CRN80_RS09420	COG1253	flavin adenine dinucleotide binding
CRN80_RS09440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CRN80_RS09445	COG3161	chorismate lyase activity
CRN80_RS09555	COG0631	protein serine/threonine phosphatase activity
CRN80_RS09560	COG2815	serine threonine protein kinase
CRN80_RS09560	COG0515	serine threonine protein kinase
CRN80_RS09565	COG0577	efflux transmembrane transporter activity
CRN80_RS09565	COG1136	(ABC) transporter
CRN80_RS09610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CRN80_RS09615	COG0583	DNA-binding transcription factor activity
CRN80_RS09625	COG0848	biopolymer transport protein
CRN80_RS09655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CRN80_RS09660	COG1758	RNA polymerase activity
CRN80_RS09665	COG0194	GDP metabolic process
CRN80_RS09670	COG1561	YicC-like family, N-terminal region
CRN80_RS09675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CRN80_RS09685	COG0708	Exodeoxyribonuclease III
CRN80_RS09690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CRN80_RS09695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CRN80_RS09700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRN80_RS09710	COG0756	dUTP diphosphatase activity
CRN80_RS09715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CRN80_RS09720	COG2003	Belongs to the UPF0758 family
CRN80_RS09730	COG0747	negative chemotaxis
CRN80_RS09735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CRN80_RS09740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CRN80_RS09750	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS09760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN80_RS09765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS09775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS09790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS09795	COG0251	oxidation-reduction process
CRN80_RS09800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CRN80_RS09815	COG0427	acetyl-CoA hydrolase
CRN80_RS09820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRN80_RS09840	COG0534	Mate efflux family protein
CRN80_RS09845	COG0583	DNA-binding transcription factor activity
CRN80_RS09855	COG0606	chelatase, subunit chli
CRN80_RS09875	COG0347	Belongs to the P(II) protein family
CRN80_RS09880	COG0004	ammonium transporteR
CRN80_RS09885	COG0432	Pfam Uncharacterised protein family UPF0047
CRN80_RS09895	COG1011	Hydrolase
CRN80_RS09900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CRN80_RS09910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CRN80_RS09915	COG0019	diaminopimelate decarboxylase activity
CRN80_RS09925	COG1965	Belongs to the frataxin family
CRN80_RS09935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN80_RS09955	COG0625	glutathione transferase activity
CRN80_RS09960	COG0165	Argininosuccinate lyase
CRN80_RS09970	COG0181	hydroxymethylbilane synthase activity
CRN80_RS09990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CRN80_RS10015	COG0488	(ABC) transporter
CRN80_RS10030	COG1280	lysine exporter protein (LysE YggA)
CRN80_RS10035	COG0672	)-iron permease
CRN80_RS10040	COG1671	Belongs to the UPF0178 family
CRN80_RS10045	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CRN80_RS10055	COG0586	Pfam SNARE associated Golgi protein
CRN80_RS10065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CRN80_RS10070	COG0248	Ppx GppA phosphatase
CRN80_RS10080	COG3121	Chaperone
CRN80_RS10085	COG3188	usher protein
CRN80_RS10095	COG1126	abc transporter atp-binding protein
CRN80_RS10100	COG0765	amino acid transport
CRN80_RS10105	COG0765	amino acid transport
CRN80_RS10110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS10115	COG2186	Transcriptional regulator
CRN80_RS10135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CRN80_RS10160	COG2271	Major facilitator Superfamily
CRN80_RS10185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CRN80_RS10205	COG3079	Belongs to the UPF0149 family
CRN80_RS10210	COG0006	proline dipeptidase activity
CRN80_RS10215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRN80_RS10220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CRN80_RS10230	COG1178	ABC-type Fe3 transport system permease component
CRN80_RS10235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CRN80_RS10240	COG0509	glycine decarboxylation via glycine cleavage system
CRN80_RS10245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CRN80_RS10260	COG0330	HflC and HflK could
CRN80_RS10265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRN80_RS10275	COG1522	sequence-specific DNA binding
CRN80_RS10290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CRN80_RS10290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CRN80_RS10295	COG4521	taurine ABC transporter
CRN80_RS10305	COG0450	alkyl hydroperoxide reductase
CRN80_RS10310	COG0431	NADPH-dependent FMN reductase
CRN80_RS10315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRN80_RS10325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN80_RS10330	COG1116	anion transmembrane transporter activity
CRN80_RS10355	COG0174	glutamine synthetase
CRN80_RS10365	COG0174	glutamine synthetase
CRN80_RS10385	COG3842	ATPase activity
CRN80_RS10390	COG1176	ABC-type spermidine putrescine transport system, permease component I
CRN80_RS10395	COG1177	transmembrane transport
CRN80_RS10415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN80_RS10420	COG1917	Cupin 2, conserved barrel domain protein
CRN80_RS10420	COG4977	sequence-specific DNA binding
CRN80_RS10450	COG1683	Conserved Protein
CRN80_RS10460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS10470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN80_RS10480	COG0277	FAD linked oxidase domain protein
CRN80_RS10485	COG0179	Fumarylacetoacetate (FAA) hydrolase
CRN80_RS10495	COG3204	pilus organization
CRN80_RS10500	COG2234	aminopeptidase activity
CRN80_RS10505	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CRN80_RS10510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CRN80_RS10525	COG0494	nUDIX hydrolase
CRN80_RS10530	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CRN80_RS10540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CRN80_RS10545	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CRN80_RS10550	COG0789	Transcriptional regulator
CRN80_RS10560	COG0583	DNA-binding transcription factor activity
CRN80_RS10565	COG3842	ATPase activity
CRN80_RS10570	COG1178	ABC-type Fe3 transport system permease component
CRN80_RS10575	COG1840	ABC-type Fe3 transport system, periplasmic component
CRN80_RS10595	COG1160	GTP binding
CRN80_RS10610	COG1823	symporter activity
CRN80_RS10620	COG0129	dihydroxy-acid dehydratase activity
CRN80_RS10630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRN80_RS10640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CRN80_RS10645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CRN80_RS10650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CRN80_RS10655	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CRN80_RS10670	COG1309	transcriptional regulator
CRN80_RS10680	COG0429	hydrolase of the alpha beta-hydrolase fold
CRN80_RS10685	COG0742	ribosomal rna small subunit methyltransferase
CRN80_RS10690	COG0612	Peptidase, M16
CRN80_RS10695	COG0612	Peptidase, M16
CRN80_RS10700	COG0552	protein localization to endoplasmic reticulum
CRN80_RS10705	COG2884	Cell division ATP-binding protein ftsE
CRN80_RS10710	COG2177	Part of the ABC transporter FtsEX involved in
CRN80_RS10730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN80_RS10735	COG2363	Small membrane protein
CRN80_RS10740	COG2022	thiamine diphosphate biosynthetic process
CRN80_RS10740	COG2104	thiamine diphosphate biosynthetic process
CRN80_RS10745	COG2022	thiamine diphosphate biosynthetic process
CRN80_RS10750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CRN80_RS10760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRN80_RS10765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CRN80_RS10775	COG2813	Specifically methylates the guanine in position
CRN80_RS10775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CRN80_RS10780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CRN80_RS10805	COG0791	NLP P60 protein
CRN80_RS10815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CRN80_RS10820	COG0540	Belongs to the ATCase OTCase family
CRN80_RS10825	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CRN80_RS10830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CRN80_RS10835	COG1678	Uncharacterized ACR, COG1678
CRN80_RS10845	COG0189	ligase activity
CRN80_RS10870	COG0643	Histidine kinase
CRN80_RS10870	COG2198	Histidine kinase
CRN80_RS10910	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CRN80_RS10915	COG3052	prosthetic group binding
CRN80_RS10935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CRN80_RS10955	COG1272	protein, Hemolysin III
CRN80_RS10980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS10985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CRN80_RS10995	COG3038	cytochrome b561
CRN80_RS11000	COG2353	YceI-like domain
CRN80_RS11005	COG0513	Belongs to the DEAD box helicase family
CRN80_RS11020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CRN80_RS11025	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CRN80_RS11040	COG2116	formate transmembrane transporter activity
CRN80_RS11045	COG1301	dicarboxylic acid transport
CRN80_RS11085	COG1422	Protein of unknown function (DUF1090)
CRN80_RS11090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CRN80_RS11095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CRN80_RS11100	COG0640	Transcriptional regulator
CRN80_RS11105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CRN80_RS11110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CRN80_RS11115	COG0126	phosphoglycerate kinase activity
CRN80_RS11150	COG1451	nucleotide metabolic process
CRN80_RS11160	COG2153	protein acetylation
CRN80_RS11170	COG1289	transmembrane transporter activity
CRN80_RS11175	COG2081	HI0933 family
CRN80_RS11180	COG0513	Belongs to the DEAD box helicase family
CRN80_RS11185	COG0477	Major facilitator Superfamily
CRN80_RS11195	COG0312	modulator of DNA gyrase
CRN80_RS11205	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CRN80_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS11215	COG1309	transcriptional regulator
CRN80_RS11220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CRN80_RS11225	COG4175	Glycine betaine
CRN80_RS11230	COG4176	ABC-type proline glycine betaine transport system permease component
CRN80_RS11240	COG1760	l-serine dehydratase
CRN80_RS11265	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRN80_RS11270	COG3246	L-lysine catabolic process to acetate
CRN80_RS11315	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS11315	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRN80_RS11320	COG0247	lactate metabolic process
CRN80_RS11320	COG2181	nitrate reductase activity
CRN80_RS11325	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CRN80_RS11335	COG4638	Rieske (2fe-2S)
CRN80_RS11345	COG1017	nitric oxide dioxygenase activity
CRN80_RS11345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN80_RS11370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CRN80_RS11400	COG1063	alcohol dehydrogenase
CRN80_RS11420	COG0204	Acyl-transferase
CRN80_RS11425	COG0189	ligase activity
CRN80_RS11425	COG4067	protein conserved in archaea
CRN80_RS11430	COG0745	RESPONSE REGULATOR receiver
CRN80_RS11435	COG2205	protein histidine kinase activity
CRN80_RS11440	COG4452	Inner membrane protein CreD
CRN80_RS11465	COG4774	siderophore transport
CRN80_RS11480	COG1595	DNA-templated transcription, initiation
CRN80_RS11485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN80_RS11500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CRN80_RS11515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CRN80_RS11525	COG3585	molybdate ion transport
CRN80_RS11525	COG2005	Transcriptional regulator
CRN80_RS11535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CRN80_RS11540	COG0156	8-amino-7-oxononanoate synthase activity
CRN80_RS11545	COG2226	methyltransferase
CRN80_RS11545	COG1073	alpha beta
CRN80_RS11565	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS11575	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS11580	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS11585	COG0583	DNA-binding transcription factor activity
CRN80_RS11590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CRN80_RS11600	COG0535	radical SAM domain protein
CRN80_RS11610	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CRN80_RS11615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CRN80_RS11625	COG1025	Belongs to the peptidase M16 family
CRN80_RS11630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CRN80_RS11655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRN80_RS11660	COG0358	DNA primase activity
CRN80_RS11665	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CRN80_RS11670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CRN80_RS11675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CRN80_RS11680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CRN80_RS11690	COG0617	tRNA 3'-terminal CCA addition
CRN80_RS11695	COG2719	SpoVR family
CRN80_RS11700	COG2718	Belongs to the UPF0229 family
CRN80_RS11705	COG2766	serine protein kinase
CRN80_RS11710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN80_RS11715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CRN80_RS11720	COG2967	ApaG domain
CRN80_RS11725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CRN80_RS11730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CRN80_RS11735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN80_RS11740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CRN80_RS11745	COG3178	'Phosphotransferase
CRN80_RS11750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CRN80_RS11755	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CRN80_RS11765	COG1454	alcohol dehydrogenase
CRN80_RS11770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CRN80_RS11775	COG0546	phosphoglycolate phosphatase activity
CRN80_RS11785	COG4625	pathogenesis
CRN80_RS11785	COG3240	lipase activity
CRN80_RS11790	COG0512	Glutamine amidotransferase of anthranilate synthase
CRN80_RS11795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CRN80_RS11800	COG0134	indole-3-glycerol-phosphate synthase activity
CRN80_RS11815	COG1765	OsmC-like protein
CRN80_RS11820	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CRN80_RS11825	COG0537	adenosine 5'-monophosphoramidase activity
CRN80_RS11830	COG4221	oxidoreductase activity
CRN80_RS11845	COG1981	membrane
CRN80_RS11850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CRN80_RS11855	COG0316	Belongs to the HesB IscA family
CRN80_RS11860	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CRN80_RS11865	COG0739	heme binding
CRN80_RS11870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CRN80_RS11905	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CRN80_RS11905	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CRN80_RS11910	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CRN80_RS11950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CRN80_RS11955	COG0081	regulation of translation
CRN80_RS11960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CRN80_RS11965	COG0222	ribosome binding
CRN80_RS11970	COG0085	RNA polymerase activity
CRN80_RS11975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CRN80_RS11980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CRN80_RS11985	COG0049	tRNA binding
CRN80_RS11990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CRN80_RS11995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CRN80_RS12000	COG0051	transcription antitermination factor activity, RNA binding
CRN80_RS12005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CRN80_RS12010	COG0088	Forms part of the polypeptide exit tunnel
CRN80_RS12015	COG0089	rRNA binding
CRN80_RS12020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CRN80_RS12025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CRN80_RS12030	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CRN80_RS12035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CRN80_RS12040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CRN80_RS12045	COG0255	Belongs to the universal ribosomal protein uL29 family
CRN80_RS12050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CRN80_RS12055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CRN80_RS12060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CRN80_RS12065	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CRN80_RS12070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CRN80_RS12075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CRN80_RS12080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CRN80_RS12085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CRN80_RS12090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CRN80_RS12095	COG1841	ribosomal large subunit assembly
CRN80_RS12100	COG0200	Binds to the 23S rRNA
CRN80_RS12110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CRN80_RS12115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CRN80_RS12120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CRN80_RS12125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CRN80_RS12130	COG0202	RNA polymerase activity
CRN80_RS12135	COG0203	ribosomal protein L17
CRN80_RS12145	COG2193	ferroxidase activity
CRN80_RS12150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CRN80_RS12155	COG2814	Major facilitator Superfamily
CRN80_RS12160	COG0629	single-stranded DNA binding
CRN80_RS12165	COG4106	trans-aconitate 2-methyltransferase activity
CRN80_RS12170	COG1335	isochorismatase
CRN80_RS12175	COG2207	Transcriptional regulator
CRN80_RS12175	COG4753	response regulator
CRN80_RS12190	COG0392	lysyltransferase activity
CRN80_RS12195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN80_RS12200	COG3568	Endonuclease Exonuclease Phosphatase
CRN80_RS12210	COG0668	transmembrane transport
CRN80_RS12260	COG3118	belongs to the thioredoxin family
CRN80_RS12275	COG2264	protein methyltransferase activity
CRN80_RS12285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CRN80_RS12290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRN80_RS12290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRN80_RS12305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CRN80_RS12310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CRN80_RS12315	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CRN80_RS12325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CRN80_RS12340	COG4206	TonB-dependent receptor
CRN80_RS12345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CRN80_RS12350	COG0142	geranyltranstransferase activity
CRN80_RS12355	COG1722	exodeoxyribonuclease VII activity
CRN80_RS12370	COG2249	NAD(P)H dehydrogenase (quinone) activity
CRN80_RS12380	COG1842	Phage shock protein A
CRN80_RS12400	COG3766	membrane
CRN80_RS12410	COG0754	glutathionylspermidine amidase activity
CRN80_RS12415	COG1335	isochorismatase
CRN80_RS12460	COG0840	transmembrane signaling receptor activity
CRN80_RS12475	COG2433	Pfam Transposase IS66
CRN80_RS12585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CRN80_RS12590	COG3228	Belongs to the MtfA family
CRN80_RS12595	COG0586	Pfam SNARE associated Golgi protein
CRN80_RS12605	COG0456	acetyltransferase
CRN80_RS12610	COG4302	ethanolamine ammonia-lyase activity
CRN80_RS12615	COG4303	Ethanolamine ammonia lyase large subunit
CRN80_RS12620	COG0531	amino acid
CRN80_RS12635	COG3284	Transcriptional regulator
CRN80_RS12645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CRN80_RS12665	COG0702	epimerase
CRN80_RS12680	COG1380	Effector of murein hydrolase LrgA
CRN80_RS12685	COG1346	cytolysis
CRN80_RS12700	COG0586	Pfam SNARE associated Golgi protein
CRN80_RS12705	COG2094	Belongs to the DNA glycosylase MPG family
CRN80_RS12710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CRN80_RS12715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CRN80_RS12725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CRN80_RS12730	COG0768	penicillin binding
CRN80_RS12735	COG0772	Belongs to the SEDS family
CRN80_RS12740	COG2951	lytic endotransglycosylase activity
CRN80_RS12750	COG1686	Belongs to the peptidase S11 family
CRN80_RS12755	COG2921	Belongs to the UPF0250 family
CRN80_RS12760	COG0321	lipoyl(octanoyl) transferase activity
CRN80_RS12765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CRN80_RS12770	COG1619	proteins homologs of microcin C7 resistance protein MccF
CRN80_RS12775	COG2951	lytic endotransglycosylase activity
CRN80_RS12785	COG1466	dna polymerase III delta subunit
CRN80_RS12795	COG0495	leucyl-tRNA aminoacylation
CRN80_RS12815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CRN80_RS12820	COG4535	Mg2 and Co2 transporter CorC
CRN80_RS12825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CRN80_RS12830	COG1702	phosphate starvation-inducible protein PhoH
CRN80_RS12835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CRN80_RS12850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CRN80_RS12855	COG0352	thiamine-phosphate diphosphorylase activity
CRN80_RS12870	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS12875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CRN80_RS12890	COG1522	sequence-specific DNA binding
CRN80_RS12900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRN80_RS12910	COG1643	Atp-dependent helicase
CRN80_RS12925	COG4993	Dehydrogenase
CRN80_RS12935	COG3622	Belongs to the hyi family
CRN80_RS12950	COG3416	Protein conserved in bacteria
CRN80_RS12960	COG1199	ATP-dependent helicase activity
CRN80_RS12960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN80_RS12970	COG1522	sequence-specific DNA binding
CRN80_RS12975	COG0697	spore germination
CRN80_RS12980	COG0513	Belongs to the DEAD box helicase family
CRN80_RS12990	COG0123	including yeast histone deacetylase and acetoin utilization protein
CRN80_RS13000	COG1946	Acyl-CoA thioesterase
CRN80_RS13015	COG2321	neutral zinc metallopeptidase
CRN80_RS13030	COG0477	Major facilitator Superfamily
CRN80_RS13035	COG1082	Xylose isomerase domain protein TIM barrel
CRN80_RS13035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CRN80_RS13040	COG1309	transcriptional regulator
CRN80_RS13045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRN80_RS13050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CRN80_RS13065	COG1629	transport
CRN80_RS13100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRN80_RS13105	COG2252	PERMEase
CRN80_RS13115	COG2080	2 iron, 2 sulfur cluster binding
CRN80_RS13120	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CRN80_RS13125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CRN80_RS13135	COG1271	oxidase subunit
CRN80_RS13140	COG1294	oxidase, subunit
CRN80_RS13150	COG2813	Specifically methylates the guanine in position
CRN80_RS13165	COG1970	mechanosensitive ion channel activity
CRN80_RS13190	COG1966	Carbon starvation protein
CRN80_RS13195	COG2879	small protein
CRN80_RS13200	COG0523	cobalamin synthesis protein
CRN80_RS13205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CRN80_RS13215	COG0488	(ABC) transporter
CRN80_RS13220	COG0583	DNA-binding transcription factor activity
CRN80_RS13225	COG2814	Major facilitator Superfamily
CRN80_RS13235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN80_RS13265	COG1067	ATP-dependent peptidase activity
CRN80_RS13280	COG2862	Uncharacterized protein family, UPF0114
CRN80_RS13340	COG0210	DNA helicase
CRN80_RS13365	COG2003	Belongs to the UPF0758 family
CRN80_RS13375	COG5377	YqaJ viral recombinase family
CRN80_RS13415	COG1999	signal sequence binding
CRN80_RS13420	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS13430	COG2814	Major facilitator Superfamily
CRN80_RS13435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS13450	COG3385	transposase activity
CRN80_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS13540	COG0582	viral genome integration into host DNA
CRN80_RS13560	COG1620	l-lactate permease
CRN80_RS13565	COG2186	Transcriptional regulator
CRN80_RS13570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CRN80_RS13580	COG2914	Belongs to the UPF0125 (RnfH) family
CRN80_RS13585	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CRN80_RS13590	COG0735	belongs to the Fur family
CRN80_RS13595	COG0497	DNA recombination
CRN80_RS13600	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CRN80_RS13605	COG0443	Heat shock 70 kDa protein
CRN80_RS13610	COG0484	heat shock protein binding
CRN80_RS13615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CRN80_RS13620	COG0505	Belongs to the CarA family
CRN80_RS13625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CRN80_RS13630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN80_RS13645	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CRN80_RS13650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CRN80_RS13655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CRN80_RS13660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRN80_RS13665	COG0149	triose-phosphate isomerase activity
CRN80_RS13670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRN80_RS13685	COG0779	Required for maturation of 30S ribosomal subunits
CRN80_RS13690	COG0195	Participates in both transcription termination and antitermination
CRN80_RS13695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CRN80_RS13700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CRN80_RS13705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CRN80_RS13710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CRN80_RS13715	COG1185	polyribonucleotide nucleotidyltransferase activity
CRN80_RS13720	COG2823	Periplasmic or secreted lipoprotein
CRN80_RS13740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRN80_RS13750	COG0166	Belongs to the GPI family
CRN80_RS13755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CRN80_RS13760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CRN80_RS13785	COG4191	Histidine kinase
CRN80_RS13795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CRN80_RS13805	COG0436	Aminotransferase
CRN80_RS13810	COG1489	DNA binding
CRN80_RS13820	COG4558	Periplasmic binding protein
CRN80_RS13825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN80_RS13830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CRN80_RS13850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN80_RS13860	COG3098	single-species biofilm formation
CRN80_RS13865	COG0028	Belongs to the TPP enzyme family
CRN80_RS13875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CRN80_RS13880	COG1183	phosphatidylcholine synthase activity
CRN80_RS13885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CRN80_RS13890	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CRN80_RS13925	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CRN80_RS13930	COG1074	ATP-dependent DNA helicase activity
CRN80_RS13935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CRN80_RS13970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CRN80_RS13985	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CRN80_RS13990	COG3483	tryptophan 2,3-dioxygenase activity
CRN80_RS13995	COG1113	amino acid transport
CRN80_RS14000	COG0543	2 iron, 2 sulfur cluster binding
CRN80_RS14000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN80_RS14005	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CRN80_RS14010	COG4638	Rieske (2fe-2S)
CRN80_RS14025	COG4948	Mandelate Racemase Muconate Lactonizing
CRN80_RS14030	COG4829	muconolactone delta-isomerase
CRN80_RS14035	COG3485	protocatechuate 3,4-dioxygenase
CRN80_RS14040	COG1522	sequence-specific DNA binding
CRN80_RS14050	COG1113	amino acid transport
CRN80_RS14065	COG0583	DNA-binding transcription factor activity
CRN80_RS14075	COG0659	secondary active sulfate transmembrane transporter activity
CRN80_RS14085	COG2610	gluconate transmembrane transporter activity
CRN80_RS14095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CRN80_RS14105	COG0840	transmembrane signaling receptor activity
CRN80_RS14115	COG0545	Peptidyl-prolyl cis-trans isomerase
CRN80_RS14120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CRN80_RS14125	COG2824	Alkylphosphonate utilization operon protein PhnA
CRN80_RS14130	COG0142	geranyltranstransferase activity
CRN80_RS14135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CRN80_RS14140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CRN80_RS14145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CRN80_RS14150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CRN80_RS14155	COG3045	CreA protein
CRN80_RS14160	COG0386	Belongs to the glutathione peroxidase family
CRN80_RS14175	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CRN80_RS14185	COG0492	ferredoxin-NADP+ reductase activity
CRN80_RS14220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CRN80_RS14225	COG0302	gtp cyclohydrolase
CRN80_RS14250	COG1366	Belongs to the anti-sigma-factor antagonist family
CRN80_RS14270	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS14290	COG2197	response regulator
CRN80_RS14295	COG2207	Transcriptional regulator
CRN80_RS14295	COG3708	Transcriptional regulator
CRN80_RS14305	COG3604	Transcriptional regulator
CRN80_RS14310	COG1017	nitric oxide dioxygenase activity
CRN80_RS14310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN80_RS14315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CRN80_RS14325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRN80_RS14330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CRN80_RS14345	COG0109	protoheme IX farnesyltransferase activity
CRN80_RS14350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CRN80_RS14365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN80_RS14400	COG4251	negative regulation of phosphorylation
CRN80_RS14435	COG1280	lysine exporter protein (LysE YggA)
CRN80_RS14500	COG0582	viral genome integration into host DNA
CRN80_RS14510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CRN80_RS14515	COG0343	queuine tRNA-ribosyltransferase activity
CRN80_RS14520	COG1862	Preprotein translocase
CRN80_RS14535	COG3134	Outer membrane lipoprotein
CRN80_RS14560	COG1104	cysteine desulfurase activity
CRN80_RS14570	COG0316	Belongs to the HesB IscA family
CRN80_RS14575	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CRN80_RS14580	COG0443	Heat shock 70 kDa protein
CRN80_RS14585	COG0633	Ferredoxin
CRN80_RS14595	COG0105	UTP biosynthetic process
CRN80_RS14600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CRN80_RS14610	COG1426	Protein conserved in bacteria
CRN80_RS14615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CRN80_RS14620	COG0124	histidyl-tRNA synthetase
CRN80_RS14640	COG1160	GTP binding
CRN80_RS14645	COG0436	Aminotransferase
CRN80_RS14655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CRN80_RS14675	COG0739	heme binding
CRN80_RS14680	COG1570	exodeoxyribonuclease VII activity
CRN80_RS14685	COG0583	DNA-binding transcription factor activity
CRN80_RS14705	COG0519	Catalyzes the synthesis of GMP from XMP
CRN80_RS14705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CRN80_RS14715	COG0784	Response regulator, receiver
CRN80_RS14715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CRN80_RS14740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CRN80_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS14750	COG0583	DNA-binding transcription factor activity
CRN80_RS14770	COG2188	Transcriptional regulator
CRN80_RS14775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN80_RS14775	COG1263	PTS System
CRN80_RS14780	COG0366	Alpha amylase catalytic
CRN80_RS14790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CRN80_RS14790	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN80_RS14795	COG2190	(PTS) system
CRN80_RS14795	COG1263	PTS System
CRN80_RS14795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN80_RS14800	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CRN80_RS14805	COG0047	phosphoribosylformylglycinamidine synthase activity
CRN80_RS14805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CRN80_RS14810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CRN80_RS14840	COG1263	PTS System
CRN80_RS14840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN80_RS14840	COG2190	(PTS) system
CRN80_RS14845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN80_RS14845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CRN80_RS14850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CRN80_RS14855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CRN80_RS14860	COG2188	Transcriptional regulator
CRN80_RS14875	COG0494	nUDIX hydrolase
CRN80_RS14900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CRN80_RS14905	COG0477	Major facilitator Superfamily
CRN80_RS14910	COG4536	flavin adenine dinucleotide binding
CRN80_RS14920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CRN80_RS14925	COG0228	four-way junction DNA binding
CRN80_RS14930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CRN80_RS14935	COG0336	Belongs to the RNA methyltransferase TrmD family
CRN80_RS14940	COG0335	large ribosomal subunit rRNA binding
CRN80_RS14945	COG1607	acyl-coa hydrolase
CRN80_RS14950	COG3263	regulation of cellular component size
CRN80_RS14955	COG4974	Belongs to the 'phage' integrase family
CRN80_RS14975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS14975	COG2205	protein histidine kinase activity
CRN80_RS14990	COG2197	response regulator
CRN80_RS15000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CRN80_RS15035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CRN80_RS15045	COG0442	prolyl-tRNA aminoacylation
CRN80_RS15050	COG2211	Major facilitator Superfamily
CRN80_RS15075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CRN80_RS15080	COG0459	protein refolding
CRN80_RS15095	COG1368	sulfuric ester hydrolase activity
CRN80_RS15115	COG3642	lipopolysaccharide core region biosynthetic process
CRN80_RS15145	COG0840	transmembrane signaling receptor activity
CRN80_RS15150	COG2832	Protein of unknown function (DUF454)
CRN80_RS15160	COG4771	TonB-dependent receptor
CRN80_RS15165	COG3712	iron ion homeostasis
CRN80_RS15210	COG2207	Transcriptional regulator
CRN80_RS15235	COG0477	Major facilitator Superfamily
CRN80_RS15245	COG4191	Histidine kinase
CRN80_RS15265	COG0469	pyruvate kinase activity
CRN80_RS15285	COG0714	Associated with various cellular activities
CRN80_RS15310	COG2925	Exonuclease
CRN80_RS15335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CRN80_RS15335	COG0438	transferase activity, transferring glycosyl groups
CRN80_RS15345	COG0433	COG0433 Predicted ATPase
CRN80_RS15355	COG0653	protein targeting
CRN80_RS15360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CRN80_RS15370	COG2096	Adenosyltransferase
CRN80_RS15375	COG4191	Histidine kinase
CRN80_RS15375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS15385	COG1666	GTP binding
CRN80_RS15390	COG0668	transmembrane transport
CRN80_RS15410	COG2900	Belongs to the SlyX family
CRN80_RS15420	COG0783	Belongs to the Dps family
CRN80_RS15435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CRN80_RS15440	COG0217	transcriptional regulatory protein
CRN80_RS15445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CRN80_RS15450	COG0632	four-way junction helicase activity
CRN80_RS15455	COG2255	four-way junction helicase activity
CRN80_RS15460	COG0824	Thioesterase
CRN80_RS15480	COG0823	Involved in the tonB-independent uptake of proteins
CRN80_RS15485	COG2885	chlorophyll binding
CRN80_RS15490	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CRN80_RS15495	COG0602	queuosine metabolic process
CRN80_RS15570	COG1538	Outer membrane efflux protein
CRN80_RS15600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CRN80_RS15610	COG1278	Cold shock
CRN80_RS15615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CRN80_RS15620	COG1760	l-serine dehydratase
CRN80_RS15625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CRN80_RS15625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CRN80_RS15630	COG0509	glycine decarboxylation via glycine cleavage system
CRN80_RS15685	COG0642	Histidine kinase
CRN80_RS15695	COG0745	RESPONSE REGULATOR receiver
CRN80_RS15700	COG2350	Protein conserved in bacteria
CRN80_RS15705	COG2917	probably involved in intracellular septation
CRN80_RS15710	COG0613	PHP domain protein
CRN80_RS15715	COG0009	L-threonylcarbamoyladenylate synthase
CRN80_RS15725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CRN80_RS15745	COG1113	amino acid transport
CRN80_RS15775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CRN80_RS15795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CRN80_RS15805	COG0583	DNA-binding transcription factor activity
CRN80_RS15810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN80_RS15825	COG1653	transport
CRN80_RS15830	COG1175	transmembrane transport
CRN80_RS15835	COG0395	ABC-type sugar transport system, permease component
CRN80_RS15840	COG3842	ATPase activity
CRN80_RS15850	COG0676	glucose-6-phosphate 1-epimerase activity
CRN80_RS15855	COG1737	Transcriptional regulator
CRN80_RS15870	COG0800	Aldolase
CRN80_RS15875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CRN80_RS15890	COG2030	dehydratase
CRN80_RS15895	COG2267	carboxylic ester hydrolase activity
CRN80_RS15920	COG3237	CsbD-like
CRN80_RS15925	COG1295	ribonuclease BN
CRN80_RS15930	COG0242	peptide deformylase activity
CRN80_RS15940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRN80_RS15955	COG2271	Major facilitator Superfamily
CRN80_RS15975	COG1609	Transcriptional regulator
CRN80_RS15980	COG3265	gluconokinase activity
CRN80_RS15990	COG0436	Aminotransferase
CRN80_RS16010	COG3795	YCII-related domain
CRN80_RS16015	COG4941	Belongs to the sigma-70 factor family
CRN80_RS16020	COG0583	DNA-binding transcription factor activity
CRN80_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS16035	COG0583	DNA-binding transcription factor activity
CRN80_RS16045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CRN80_RS16055	COG1984	allophanate hydrolase subunit 2
CRN80_RS16070	COG0584	glycerophosphoryl diester phosphodiesterase
CRN80_RS16090	COG2329	Antibiotic biosynthesis monooxygenase
CRN80_RS16095	COG0504	CTP synthase activity
CRN80_RS16110	COG3706	GGDEF domain
CRN80_RS16130	COG0154	amidase activity
CRN80_RS16145	COG2814	Major facilitator Superfamily
CRN80_RS16160	COG0765	amino acid transport
CRN80_RS16165	COG0165	Argininosuccinate lyase
CRN80_RS16195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRN80_RS16205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN80_RS16210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS16250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CRN80_RS16265	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS16270	COG3724	N-succinylarginine dihydrolase activity
CRN80_RS16280	COG2988	succinylglutamate desuccinylase activity
CRN80_RS16290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CRN80_RS16295	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CRN80_RS16300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CRN80_RS16305	COG0527	aspartate kinase activity
CRN80_RS16310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CRN80_RS16330	COG2239	Acts as a magnesium transporter
CRN80_RS16355	COG3593	DNA synthesis involved in DNA repair
CRN80_RS16370	COG2433	Pfam Transposase IS66
CRN80_RS16385	COG1396	sequence-specific DNA binding
CRN80_RS16585	COG0477	Major facilitator Superfamily
CRN80_RS16590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CRN80_RS16610	COG0784	Response regulator, receiver
CRN80_RS16610	COG0835	chemotaxis
CRN80_RS16615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CRN80_RS16620	COG1815	bacterial-type flagellum-dependent cell motility
CRN80_RS16630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CRN80_RS16655	COG0745	RESPONSE REGULATOR receiver
CRN80_RS16660	COG2205	protein histidine kinase activity
CRN80_RS16685	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CRN80_RS16700	COG0583	DNA-binding transcription factor activity
CRN80_RS16715	COG3220	belongs to the UPF0276 family
CRN80_RS16770	COG2271	Major facilitator Superfamily
CRN80_RS16780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRN80_RS16790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRN80_RS16800	COG0583	DNA-binding transcription factor activity
CRN80_RS16820	COG2188	Transcriptional regulator
CRN80_RS16825	COG1397	ADP-ribosylglycohydrolase
CRN80_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS16870	COG1879	ABC-type sugar transport system periplasmic component
CRN80_RS16875	COG1129	ABC transporter
CRN80_RS16880	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN80_RS16885	COG1414	Transcriptional regulator
CRN80_RS16890	COG1064	alcohol dehydrogenase
CRN80_RS16895	COG2207	Transcriptional regulator
CRN80_RS16930	COG2885	chlorophyll binding
CRN80_RS16935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS16965	COG2308	Evidence 4 Homologs of previously reported genes of
CRN80_RS16975	COG1305	Transglutaminase-like
CRN80_RS16985	COG0183	Belongs to the thiolase family
CRN80_RS16990	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRN80_RS16990	COG1024	Enoyl-CoA hydratase
CRN80_RS16995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CRN80_RS16995	COG0519	Catalyzes the synthesis of GMP from XMP
CRN80_RS17000	COG0598	Magnesium transport protein CorA
CRN80_RS17030	COG0653	protein targeting
CRN80_RS17065	COG1733	regulation of RNA biosynthetic process
CRN80_RS17070	COG2085	NADP oxidoreductase coenzyme F420-dependent
CRN80_RS17105	COG3011	Protein conserved in bacteria
CRN80_RS17135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN80_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS17145	COG0583	DNA-binding transcription factor activity
CRN80_RS17155	COG1953	Uracil, thiamine, allantoin
CRN80_RS17165	COG0560	Phosphoserine phosphatase
CRN80_RS17175	COG0189	ligase activity
CRN80_RS17185	COG4067	protein conserved in archaea
CRN80_RS17185	COG0189	ligase activity
CRN80_RS17190	COG1802	Transcriptional regulator
CRN80_RS17200	COG0372	Belongs to the citrate synthase family
CRN80_RS17215	COG2079	MmgE PrpD family protein
CRN80_RS17220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CRN80_RS17225	COG1045	serine acetyltransferase
CRN80_RS17230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRN80_RS17245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS17250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CRN80_RS17265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CRN80_RS17290	COG3047	cAMP biosynthetic process
CRN80_RS17290	COG2885	chlorophyll binding
CRN80_RS17295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CRN80_RS17300	COG0243	molybdopterin cofactor binding
CRN80_RS17305	COG2146	nitrite reductase [NAD(P)H] activity
CRN80_RS17310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRN80_RS17320	COG2223	nitrite transmembrane transporter activity
CRN80_RS17325	COG3707	response regulator
CRN80_RS17330	COG1116	anion transmembrane transporter activity
CRN80_RS17330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRN80_RS17340	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CRN80_RS17355	COG0167	dihydroorotate dehydrogenase activity
CRN80_RS17360	COG3130	regulation of translation
CRN80_RS17365	COG0116	Belongs to the methyltransferase superfamily
CRN80_RS17365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRN80_RS17385	COG3171	Protein conserved in bacteria
CRN80_RS17390	COG3135	benzoate transporter
CRN80_RS17400	COG0402	S-adenosylhomocysteine deaminase activity
CRN80_RS17410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CRN80_RS17430	COG3115	cell septum assembly
CRN80_RS17435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CRN80_RS17470	COG0583	DNA-binding transcription factor activity
CRN80_RS17480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CRN80_RS17485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CRN80_RS17490	COG2130	NADP-dependent
CRN80_RS17495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CRN80_RS17500	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS17505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRN80_RS17510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRN80_RS17545	COG0348	domain, Protein
CRN80_RS17560	COG2010	Cytochrome c
CRN80_RS17575	COG3278	Belongs to the heme-copper respiratory oxidase family
CRN80_RS17580	COG2010	Cytochrome c
CRN80_RS17595	COG3278	Belongs to the heme-copper respiratory oxidase family
CRN80_RS17610	COG0840	transmembrane signaling receptor activity
CRN80_RS17630	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CRN80_RS17635	COG1643	Atp-dependent helicase
CRN80_RS17655	COG1595	DNA-templated transcription, initiation
CRN80_RS17665	COG2188	Transcriptional regulator
CRN80_RS17685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRN80_RS17690	COG1132	(ABC) transporter
CRN80_RS17715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRN80_RS17725	COG3321	synthase
CRN80_RS17725	COG0604	alcohol dehydrogenase
CRN80_RS17730	COG4221	oxidoreductase activity
CRN80_RS17740	COG0668	transmembrane transport
CRN80_RS17745	COG0513	Belongs to the DEAD box helicase family
CRN80_RS17760	COG2132	Multicopper oxidase
CRN80_RS17785	COG2996	Protein conserved in bacteria
CRN80_RS17800	COG0583	DNA-binding transcription factor activity
CRN80_RS17805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRN80_RS17835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRN80_RS17840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CRN80_RS17845	COG3956	TIGRFAM MazG family protein
CRN80_RS17850	COG3122	Protein conserved in bacteria
CRN80_RS17860	COG2814	Major facilitator Superfamily
CRN80_RS17865	COG4264	IucA IucC family
CRN80_RS17885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CRN80_RS17890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CRN80_RS17900	COG0628	permease
CRN80_RS17905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CRN80_RS17910	COG0791	NLP P60 protein
CRN80_RS17915	COG0791	NLP P60 protein
CRN80_RS17930	COG1797	cobyrinic acid a,c-diamide synthase activity
CRN80_RS17935	COG0778	Nitroreductase
CRN80_RS17940	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CRN80_RS17950	COG1492	cobalamin metabolic process
CRN80_RS17960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CRN80_RS17965	COG0406	alpha-ribazole phosphatase activity
CRN80_RS17970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CRN80_RS17975	COG1846	Transcriptional regulator
CRN80_RS18025	COG2205	protein histidine kinase activity
CRN80_RS18030	COG2832	Protein of unknown function (DUF454)
CRN80_RS18040	COG0514	ATP-dependent DNA helicase (RecQ)
CRN80_RS18045	COG1846	Transcriptional regulator
CRN80_RS18050	COG1752	Esterase of the alpha-beta hydrolase superfamily
CRN80_RS18065	COG2207	Transcriptional regulator
CRN80_RS18080	COG2154	pterin-4-alpha-carbinolamine dehydratase
CRN80_RS18090	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CRN80_RS18100	COG4787	bacterial-type flagellum-dependent cell motility
CRN80_RS18110	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CRN80_RS18115	COG1706	bacterial-type flagellum-dependent cell motility
CRN80_RS18125	COG1256	bacterial-type flagellum assembly
CRN80_RS18135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CRN80_RS18140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CRN80_RS18150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CRN80_RS18180	COG1677	Flagellar hook-basal body complex protein FliE
CRN80_RS18220	COG0745	RESPONSE REGULATOR receiver
CRN80_RS18270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRN80_RS18280	COG1278	Cold shock
CRN80_RS18320	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CRN80_RS18325	COG0643	Histidine kinase
CRN80_RS18325	COG2198	Histidine kinase
CRN80_RS18325	COG0784	Response regulator, receiver
CRN80_RS18330	COG2201	protein-glutamate methylesterase activity
CRN80_RS18335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CRN80_RS18340	COG1360	Flagellar Motor Protein
CRN80_RS18345	COG1192	Involved in chromosome partitioning
CRN80_RS18355	COG0835	chemotaxis
CRN80_RS18375	COG1597	lipid kinase activity
CRN80_RS18380	COG2197	response regulator
CRN80_RS18385	COG3851	Histidine kinase
CRN80_RS18400	COG3217	Mosc domain protein beta barrel domain protein
CRN80_RS18400	COG0633	Ferredoxin
CRN80_RS18405	COG3123	guanosine phosphorylase activity
CRN80_RS18425	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS18430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CRN80_RS18445	COG1309	transcriptional regulator
CRN80_RS18485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN80_RS18530	COG1473	amidohydrolase
CRN80_RS18535	COG0668	transmembrane transport
CRN80_RS18540	COG1362	aminopeptidase activity
CRN80_RS18545	COG0564	pseudouridine synthase activity
CRN80_RS18550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CRN80_RS18555	COG2894	cell division
CRN80_RS18560	COG0850	regulation of cytokinetic process
CRN80_RS18565	COG1560	Kdo2-lipid A biosynthetic process
CRN80_RS18580	COG2233	PERMEase
CRN80_RS18590	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CRN80_RS18595	COG4266	Belongs to the allantoicase family
CRN80_RS18630	COG2252	PERMEase
CRN80_RS18635	COG0625	glutathione transferase activity
CRN80_RS18640	COG0583	DNA-binding transcription factor activity
CRN80_RS18645	COG2851	Citrate transporter
CRN80_RS18675	COG0302	gtp cyclohydrolase
CRN80_RS18680	COG2840	Smr protein MutS2
CRN80_RS18705	COG1073	alpha beta
CRN80_RS18710	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CRN80_RS18720	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CRN80_RS18725	COG2197	response regulator
CRN80_RS18740	COG0318	PFAM AMP-dependent synthetase and ligase
CRN80_RS18760	COG1368	sulfuric ester hydrolase activity
CRN80_RS18775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CRN80_RS18780	COG3089	Belongs to the UPF0270 family
CRN80_RS18790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CRN80_RS18790	COG0189	ligase activity
CRN80_RS18795	COG0367	asparagine synthase
CRN80_RS18800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS18800	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CRN80_RS18805	COG2326	polyphosphate kinase activity
CRN80_RS18810	COG0183	Belongs to the thiolase family
CRN80_RS18820	COG0697	spore germination
CRN80_RS18825	COG0114	fumarate hydratase activity
CRN80_RS18835	COG0271	Belongs to the BolA IbaG family
CRN80_RS18870	COG1054	Belongs to the UPF0176 family
CRN80_RS18885	COG5002	protein histidine kinase activity
CRN80_RS18885	COG5001	Diguanylate cyclase
CRN80_RS18900	COG1304	FMN binding
CRN80_RS18905	COG0583	DNA-binding transcription factor activity
CRN80_RS18930	COG2207	Transcriptional regulator
CRN80_RS18940	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CRN80_RS18945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CRN80_RS18965	COG0583	DNA-binding transcription factor activity
CRN80_RS19000	COG0745	RESPONSE REGULATOR receiver
CRN80_RS19005	COG2205	protein histidine kinase activity
CRN80_RS19020	COG2391	methyltransferase activity
CRN80_RS19080	COG3657	addiction module killer protein
CRN80_RS19095	COG3469	chitinase activity
CRN80_RS19110	COG2186	Transcriptional regulator
CRN80_RS19115	COG2384	SAM-dependent methyltransferase
CRN80_RS19255	COG2226	methyltransferase
CRN80_RS19285	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CRN80_RS19300	COG1120	ATPase activity
CRN80_RS19305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN80_RS19310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRN80_RS19315	COG1864	DNA RNA non-specific endonuclease
CRN80_RS19315	COG3591	Belongs to the peptidase S1B family
CRN80_RS19330	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS19335	COG0583	DNA-binding transcription factor activity
CRN80_RS19350	COG0556	nucleotide-excision repair
CRN80_RS19355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CRN80_RS19385	COG0596	Alpha beta hydrolase
CRN80_RS19395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN80_RS19410	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CRN80_RS19415	COG0066	3-isopropylmalate dehydratase activity
CRN80_RS19420	COG2226	methyltransferase
CRN80_RS19425	COG0473	3-isopropylmalate dehydrogenase activity
CRN80_RS19450	COG0135	phosphoribosylanthranilate isomerase activity
CRN80_RS19455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CRN80_RS19460	COG0285	dihydrofolate synthase activity
CRN80_RS19465	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CRN80_RS19480	COG1286	toxin biosynthetic process
CRN80_RS19520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CRN80_RS19530	COG2010	Cytochrome c
CRN80_RS19540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS19575	COG0642	Histidine kinase
CRN80_RS19590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN80_RS19605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CRN80_RS19635	COG1129	ABC transporter
CRN80_RS19640	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN80_RS19645	COG1609	Transcriptional regulator
CRN80_RS19650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN80_RS19655	COG1869	D-ribose catabolic process
CRN80_RS19680	COG1278	Cold shock
CRN80_RS19690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CRN80_RS19695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CRN80_RS19700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CRN80_RS19705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CRN80_RS19710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CRN80_RS19715	COG0072	phenylalanine-tRNA ligase activity
CRN80_RS19720	COG0776	regulation of translation
CRN80_RS19800	COG5532	Uncharacterized conserved protein (DUF2303)
CRN80_RS19845	COG0305	Participates in initiation and elongation during chromosome replication
CRN80_RS19945	COG3179	chitinase
CRN80_RS19990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS20000	COG1609	Transcriptional regulator
CRN80_RS20005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRN80_RS20010	COG1459	type II secretion system
CRN80_RS20015	COG2165	general secretion pathway protein
CRN80_RS20025	COG2165	general secretion pathway protein
CRN80_RS20035	COG3156	type II secretion system protein K
CRN80_RS20040	COG3166	PFAM Fimbrial assembly family protein
CRN80_RS20075	COG1126	abc transporter atp-binding protein
CRN80_RS20080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS20110	COG0667	Aldo Keto reductase
CRN80_RS20115	COG0625	glutathione transferase activity
CRN80_RS20145	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS20150	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS20155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CRN80_RS20165	COG0531	amino acid
CRN80_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS20215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS20220	COG1846	Transcriptional regulator
CRN80_RS20230	COG3971	2-oxopent-4-enoate hydratase activity
CRN80_RS20235	COG2271	Major facilitator Superfamily
CRN80_RS20245	COG3384	dioxygenase
CRN80_RS20250	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS20295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CRN80_RS20300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CRN80_RS20315	COG0577	efflux transmembrane transporter activity
CRN80_RS20350	COG1879	ABC-type sugar transport system periplasmic component
CRN80_RS20360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN80_RS20365	COG1063	alcohol dehydrogenase
CRN80_RS20370	COG1070	Carbohydrate kinase
CRN80_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS20380	COG1609	Transcriptional regulator
CRN80_RS20430	COG2186	Transcriptional regulator
CRN80_RS20440	COG1538	Outer membrane efflux protein
CRN80_RS20445	COG0577	efflux transmembrane transporter activity
CRN80_RS20445	COG1136	(ABC) transporter
CRN80_RS20450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS20500	COG4215	(ABC) transporter
CRN80_RS20510	COG2423	ornithine cyclodeaminase activity
CRN80_RS20525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRN80_RS20530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN80_RS20540	COG0022	dehydrogenase e1 component
CRN80_RS20545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRN80_RS20550	COG1522	sequence-specific DNA binding
CRN80_RS20565	COG0640	Transcriptional regulator
CRN80_RS20605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CRN80_RS20615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN80_RS20635	COG1309	transcriptional regulator
CRN80_RS20655	COG1953	Uracil, thiamine, allantoin
CRN80_RS20690	COG1686	Belongs to the peptidase S11 family
CRN80_RS20700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CRN80_RS20725	COG0544	peptidyl-prolyl cis-trans isomerase activity
CRN80_RS20730	COG0740	serine-type endopeptidase activity
CRN80_RS20735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CRN80_RS20740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CRN80_RS20745	COG0776	regulation of translation
CRN80_RS20750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN80_RS20755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CRN80_RS20775	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRN80_RS20775	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS20785	COG3038	cytochrome b561
CRN80_RS20790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN80_RS20795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CRN80_RS20800	COG0583	DNA-binding transcription factor activity
CRN80_RS20810	COG2271	Major facilitator Superfamily
CRN80_RS20815	COG0217	transcriptional regulatory protein
CRN80_RS20825	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CRN80_RS20900	COG2866	Carboxypeptidase
CRN80_RS20930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CRN80_RS20935	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS20940	COG0318	PFAM AMP-dependent synthetase and ligase
CRN80_RS20955	COG0789	Transcriptional regulator
CRN80_RS20970	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS20975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CRN80_RS20985	COG0708	Exodeoxyribonuclease III
CRN80_RS20995	COG0729	surface antigen
CRN80_RS21000	COG2911	Protein conserved in bacteria
CRN80_RS21005	COG1846	Transcriptional regulator
CRN80_RS21015	COG1566	PFAM secretion protein HlyD family protein
CRN80_RS21020	COG2814	Major facilitator Superfamily
CRN80_RS21025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CRN80_RS21035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CRN80_RS21040	COG0215	cysteine-tRNA ligase activity
CRN80_RS21060	COG2212	antiporter activity
CRN80_RS21070	COG0651	ATP synthesis coupled electron transport
CRN80_RS21075	COG1006	Multisubunit Na H antiporter MnhC subunit
CRN80_RS21080	COG2111	Na H antiporter
CRN80_RS21080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRN80_RS21105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS21115	COG0577	efflux transmembrane transporter activity
CRN80_RS21115	COG1136	(ABC) transporter
CRN80_RS21120	COG1136	(ABC) transporter
CRN80_RS21120	COG0577	efflux transmembrane transporter activity
CRN80_RS21140	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS21190	COG2944	sequence-specific DNA binding
CRN80_RS21195	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CRN80_RS21200	COG1007	ATP synthesis coupled electron transport
CRN80_RS21215	COG0713	ATP synthesis coupled electron transport
CRN80_RS21225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN80_RS21230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CRN80_RS21235	COG1034	ATP synthesis coupled electron transport
CRN80_RS21250	COG0649	NAD binding
CRN80_RS21250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN80_RS21255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN80_RS21260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CRN80_RS21270	COG2224	Isocitrate lyase
CRN80_RS21280	COG2153	protein acetylation
CRN80_RS21285	COG2850	peptidyl-arginine hydroxylation
CRN80_RS21295	COG2915	High frequency lysogenization protein hflD homolog
CRN80_RS21300	COG0482	sulfurtransferase activity
CRN80_RS21320	COG1278	Cold shock
CRN80_RS21325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CRN80_RS21330	COG0542	response to heat
CRN80_RS21340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CRN80_RS21345	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CRN80_RS21350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CRN80_RS21355	COG1674	ftsk spoiiie
CRN80_RS21360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CRN80_RS21365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CRN80_RS21370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CRN80_RS21375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CRN80_RS21380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CRN80_RS21380	COG1648	precorrin-2 dehydrogenase activity
CRN80_RS21385	COG0435	Glutathione S-transferase
CRN80_RS21390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CRN80_RS21395	COG2920	part of a sulfur-relay system
CRN80_RS21415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CRN80_RS21425	COG3091	SprT-like family
CRN80_RS21435	COG0037	tRNA processing
CRN80_RS21455	COG1393	Belongs to the ArsC family
CRN80_RS21480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN80_RS21485	COG5002	protein histidine kinase activity
CRN80_RS21485	COG2205	protein histidine kinase activity
CRN80_RS21485	COG0784	Response regulator, receiver
CRN80_RS21505	COG2333	competence protein COMEC
CRN80_RS21505	COG0658	competence protein
CRN80_RS21510	COG0811	peptide transport
CRN80_RS21515	COG0848	biopolymer transport protein
CRN80_RS21520	COG1663	tetraacyldisaccharide 4'-kinase activity
CRN80_RS21525	COG2835	tetraacyldisaccharide 4'-kinase activity
CRN80_RS21530	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CRN80_RS21535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRN80_RS21540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CRN80_RS21600	COG0494	nUDIX hydrolase
CRN80_RS21605	COG1403	HNH endonuclease
CRN80_RS21635	COG3284	Transcriptional regulator
CRN80_RS21640	COG3842	ATPase activity
CRN80_RS21645	COG3842	ATPase activity
CRN80_RS21655	COG0395	ABC-type sugar transport system, permease component
CRN80_RS21690	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CRN80_RS21695	COG1063	alcohol dehydrogenase
CRN80_RS21730	COG2814	Major facilitator Superfamily
CRN80_RS21855	COG3383	formate dehydrogenase (NAD+) activity
CRN80_RS21860	COG1177	transmembrane transport
CRN80_RS21865	COG1176	ABC-type spermidine putrescine transport system, permease component I
CRN80_RS21870	COG3842	ATPase activity
CRN80_RS21875	COG1414	Transcriptional regulator
CRN80_RS21880	COG0534	Mate efflux family protein
CRN80_RS21970	COG1741	Belongs to the pirin family
CRN80_RS21990	COG1917	Cupin 2, conserved barrel domain protein
CRN80_RS21990	COG4977	sequence-specific DNA binding
CRN80_RS22000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS22015	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CRN80_RS22020	COG1335	isochorismatase
CRN80_RS22025	COG0583	DNA-binding transcription factor activity
CRN80_RS22035	COG3447	MASE1 domain protein
CRN80_RS22035	COG5001	Diguanylate cyclase
CRN80_RS22035	COG5002	protein histidine kinase activity
CRN80_RS22050	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CRN80_RS22070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN80_RS22075	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS22080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS22100	COG0583	DNA-binding transcription factor activity
CRN80_RS22115	COG1349	DNA-binding transcription factor activity
CRN80_RS22120	COG1304	FMN binding
CRN80_RS22130	COG0494	nUDIX hydrolase
CRN80_RS22140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN80_RS22160	COG4191	Histidine kinase
CRN80_RS22160	COG0784	Response regulator, receiver
CRN80_RS22180	COG5383	Protein conserved in bacteria
CRN80_RS22200	COG0616	signal peptide processing
CRN80_RS22210	COG2376	Dihydroxyacetone kinase
CRN80_RS22215	COG1063	alcohol dehydrogenase
CRN80_RS22220	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS22225	COG1879	ABC-type sugar transport system periplasmic component
CRN80_RS22230	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN80_RS22235	COG1129	ABC transporter
CRN80_RS22240	COG0698	ribose 5-phosphate isomerase
CRN80_RS22250	COG1253	flavin adenine dinucleotide binding
CRN80_RS22265	COG0765	amino acid transport
CRN80_RS22270	COG0765	amino acid transport
CRN80_RS22275	COG1126	abc transporter atp-binding protein
CRN80_RS22295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN80_RS22300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN80_RS22310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN80_RS22315	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS22320	COG2610	gluconate transmembrane transporter activity
CRN80_RS22330	COG3829	transcription factor binding
CRN80_RS22330	COG3290	protein histidine kinase activity
CRN80_RS22335	COG4172	Belongs to the ABC transporter superfamily
CRN80_RS22340	COG4239	(ABC) transporter, permease
CRN80_RS22345	COG4174	ABC transporter (Permease)
CRN80_RS22350	COG4166	transmembrane transport
CRN80_RS22355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN80_RS22410	COG2204	response regulator
CRN80_RS22445	COG0631	protein serine/threonine phosphatase activity
CRN80_RS22465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRN80_RS22485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRN80_RS22490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRN80_RS22495	COG2890	protein-(glutamine-N5) methyltransferase activity
CRN80_RS22525	COG0673	inositol 2-dehydrogenase activity
CRN80_RS22565	COG1999	signal sequence binding
CRN80_RS22590	COG0693	protein deglycase activity
CRN80_RS22610	COG2207	Transcriptional regulator
CRN80_RS22625	COG2066	Belongs to the glutaminase family
CRN80_RS22645	COG0019	diaminopimelate decarboxylase activity
CRN80_RS22650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CRN80_RS22665	COG0596	Alpha beta hydrolase
CRN80_RS22670	COG0625	glutathione transferase activity
CRN80_RS22705	COG2205	protein histidine kinase activity
CRN80_RS22710	COG0745	RESPONSE REGULATOR receiver
CRN80_RS22730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN80_RS22740	COG3718	enzyme involved in inositol metabolism
CRN80_RS22755	COG0673	inositol 2-dehydrogenase activity
CRN80_RS22760	COG0673	inositol 2-dehydrogenase activity
CRN80_RS22770	COG1129	ABC transporter
CRN80_RS22775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN80_RS22830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS22870	COG1335	isochorismatase
CRN80_RS22875	COG1944	ATP diphosphatase activity
CRN80_RS22880	COG0626	cystathionine gamma-synthase activity
CRN80_RS22900	COG2814	Major facilitator Superfamily
CRN80_RS22910	COG0583	DNA-binding transcription factor activity
CRN80_RS22920	COG0477	Major facilitator Superfamily
CRN80_RS22925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CRN80_RS22965	COG0840	transmembrane signaling receptor activity
CRN80_RS23015	COG1640	4-alpha-glucanotransferase
CRN80_RS23020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CRN80_RS23025	COG0297	glycogen (starch) synthase activity
CRN80_RS23030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN80_RS23035	COG0596	Alpha beta hydrolase
CRN80_RS23045	COG1238	metal cluster binding
CRN80_RS23060	COG0667	Aldo Keto reductase
CRN80_RS23065	COG0583	DNA-binding transcription factor activity
CRN80_RS23085	COG1116	anion transmembrane transporter activity
CRN80_RS23085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRN80_RS23090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CRN80_RS23095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CRN80_RS23115	COG2366	antibiotic biosynthetic process
CRN80_RS23165	COG1397	ADP-ribosylglycohydrolase
CRN80_RS23170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS23180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN80_RS23185	COG3938	Belongs to the proline racemase family
CRN80_RS23190	COG0531	amino acid
CRN80_RS23215	COG0583	DNA-binding transcription factor activity
CRN80_RS23220	COG1335	isochorismatase
CRN80_RS23225	COG1335	isochorismatase
CRN80_RS23235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CRN80_RS23245	COG0581	inorganic phosphate transmembrane transporter activity
CRN80_RS23250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CRN80_RS23335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CRN80_RS23355	COG0488	(ABC) transporter
CRN80_RS23365	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CRN80_RS23385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRN80_RS23385	COG2169	Transcriptional regulator
CRN80_RS23390	COG3145	DNA-N1-methyladenine dioxygenase activity
CRN80_RS23425	COG3539	Fimbrial protein
CRN80_RS23430	COG3539	Fimbrial protein
CRN80_RS23445	COG3121	Chaperone
CRN80_RS23515	COG2200	EAL domain
CRN80_RS23525	COG3121	Chaperone
CRN80_RS23530	COG3188	usher protein
CRN80_RS23540	COG3121	Chaperone
CRN80_RS23575	COG0667	Aldo Keto reductase
CRN80_RS23580	COG0583	DNA-binding transcription factor activity
CRN80_RS23590	COG2271	Major facilitator Superfamily
CRN80_RS23595	COG3835	regulator
CRN80_RS23610	COG1929	Belongs to the glycerate kinase type-1 family
CRN80_RS23635	COG1247	-acetyltransferase
CRN80_RS23640	COG1794	racemase activity, acting on amino acids and derivatives
CRN80_RS23645	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CRN80_RS23665	COG2198	Histidine kinase
CRN80_RS23665	COG0784	Response regulator, receiver
CRN80_RS23665	COG2205	protein histidine kinase activity
CRN80_RS23670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CRN80_RS23680	COG5002	protein histidine kinase activity
CRN80_RS23680	COG2205	protein histidine kinase activity
CRN80_RS23680	COG0784	Response regulator, receiver
CRN80_RS23700	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CRN80_RS23710	COG3781	membrane
CRN80_RS23715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN80_RS23730	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS23735	COG1024	Enoyl-CoA hydratase
CRN80_RS23745	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS23750	COG1024	Enoyl-CoA hydratase
CRN80_RS23775	COG2076	Multidrug Resistance protein
CRN80_RS23780	COG2076	Multidrug Resistance protein
CRN80_RS23785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CRN80_RS23790	COG0726	polysaccharide deacetylase
CRN80_RS23795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CRN80_RS23795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN80_RS23800	COG0463	Glycosyl transferase, family 2
CRN80_RS23810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CRN80_RS23820	COG2814	Major facilitator Superfamily
CRN80_RS23840	COG2205	protein histidine kinase activity
CRN80_RS23875	COG0596	Alpha beta hydrolase
CRN80_RS23880	COG0596	Alpha beta hydrolase
CRN80_RS23885	COG3237	CsbD-like
CRN80_RS23890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CRN80_RS23895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CRN80_RS23895	COG1024	Enoyl-CoA hydratase
CRN80_RS23900	COG0583	DNA-binding transcription factor activity
CRN80_RS23910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS23940	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CRN80_RS23950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN80_RS23960	COG0826	peptidase U32
CRN80_RS23970	COG1522	sequence-specific DNA binding
CRN80_RS23995	COG2308	Evidence 4 Homologs of previously reported genes of
CRN80_RS24005	COG1199	ATP-dependent helicase activity
CRN80_RS24020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CRN80_RS24065	COG1113	amino acid transport
CRN80_RS24090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS24110	COG0210	DNA helicase
CRN80_RS24130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS24140	COG3321	synthase
CRN80_RS24140	COG0604	alcohol dehydrogenase
CRN80_RS24140	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS24215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN80_RS24220	COG1309	transcriptional regulator
CRN80_RS24240	COG2814	Major facilitator Superfamily
CRN80_RS24245	COG1538	Outer membrane efflux protein
CRN80_RS24250	COG0583	DNA-binding transcription factor activity
CRN80_RS24275	COG2207	Transcriptional regulator
CRN80_RS24280	COG0672	)-iron permease
CRN80_RS24285	COG2822	iron ion transport
CRN80_RS24295	COG2822	iron ion transport
CRN80_RS24300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN80_RS24320	COG2133	pyrroloquinoline quinone binding
CRN80_RS24330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CRN80_RS24365	COG0488	(ABC) transporter
CRN80_RS24385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRN80_RS24390	COG0583	DNA-binding transcription factor activity
CRN80_RS24405	COG1968	undecaprenyl-diphosphatase activity
CRN80_RS24410	COG0840	transmembrane signaling receptor activity
CRN80_RS24445	COG2079	MmgE PrpD family protein
CRN80_RS24450	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS24455	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CRN80_RS24460	COG0583	DNA-binding transcription factor activity
CRN80_RS24480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CRN80_RS24495	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRN80_RS24530	COG2816	NAD+ diphosphatase activity
CRN80_RS24535	COG1024	Enoyl-CoA hydratase
CRN80_RS24540	COG3012	SEC-C Motif Domain Protein
CRN80_RS24540	COG3318	Belongs to the UPF0149 family
CRN80_RS24545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CRN80_RS24575	COG0477	Major facilitator Superfamily
CRN80_RS24580	COG2186	Transcriptional regulator
CRN80_RS24585	COG0579	oxidoreductase
CRN80_RS24590	COG0477	Major facilitator Superfamily
CRN80_RS24600	COG0784	Response regulator, receiver
CRN80_RS24600	COG4191	Histidine kinase
CRN80_RS24610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CRN80_RS24630	COG1285	pathogenesis
CRN80_RS24640	COG0348	domain, Protein
CRN80_RS24645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS24655	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS24665	COG1538	Outer membrane efflux protein
CRN80_RS24735	COG1175	transmembrane transport
CRN80_RS24755	COG1070	Carbohydrate kinase
CRN80_RS24780	COG0024	Methionine aminopeptidase
CRN80_RS24785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN80_RS24795	COG0730	response to heat
CRN80_RS24815	COG2205	protein histidine kinase activity
CRN80_RS24820	COG0745	RESPONSE REGULATOR receiver
CRN80_RS24825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS24830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN80_RS24865	COG1609	Transcriptional regulator
CRN80_RS24875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN80_RS24895	COG2233	PERMEase
CRN80_RS24920	COG0583	DNA-binding transcription factor activity
CRN80_RS24985	COG2204	response regulator
CRN80_RS24995	COG0561	phosphatase activity
CRN80_RS25000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CRN80_RS25005	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CRN80_RS25010	COG2194	sulfuric ester hydrolase activity
CRN80_RS25030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CRN80_RS25035	COG2271	Major facilitator Superfamily
CRN80_RS25045	COG0477	Major facilitator Superfamily
CRN80_RS25055	COG2207	Transcriptional regulator
CRN80_RS25070	COG2207	Transcriptional regulator
CRN80_RS25075	COG2223	nitrite transmembrane transporter activity
CRN80_RS25080	COG0673	inositol 2-dehydrogenase activity
CRN80_RS25090	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS25110	COG0154	amidase activity
CRN80_RS25120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN80_RS25125	COG0697	spore germination
CRN80_RS25170	COG2205	protein histidine kinase activity
CRN80_RS25175	COG0745	RESPONSE REGULATOR receiver
CRN80_RS25190	COG0589	response to stress
CRN80_RS25210	COG0814	amino acid
CRN80_RS25230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN80_RS25240	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS25255	COG2818	Glycosylase
CRN80_RS25285	COG0714	Associated with various cellular activities
CRN80_RS25330	COG3291	Pkd domain containing protein
CRN80_RS25335	COG0420	3'-5' exonuclease activity
CRN80_RS25355	COG2706	6-phosphogluconolactonase activity
CRN80_RS25395	COG0318	PFAM AMP-dependent synthetase and ligase
CRN80_RS25410	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS25415	COG1960	acyl-CoA dehydrogenase activity
CRN80_RS25435	COG3239	Fatty acid desaturase
CRN80_RS25460	COG0308	aminopeptidase N
CRN80_RS25470	COG3139	Protein of unknown function (DUF1315)
CRN80_RS25480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CRN80_RS25485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CRN80_RS25545	COG0316	Belongs to the HesB IscA family
CRN80_RS25545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CRN80_RS25555	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CRN80_RS25585	COG1879	ABC-type sugar transport system periplasmic component
CRN80_RS25645	COG0028	Belongs to the TPP enzyme family
CRN80_RS25650	COG0431	NADPH-dependent FMN reductase
CRN80_RS25690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN80_RS25695	COG0328	RNA-DNA hybrid ribonuclease activity
CRN80_RS25705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN80_RS25710	COG0741	lytic transglycosylase activity
CRN80_RS25710	COG1388	LysM domain
CRN80_RS25720	COG4166	transmembrane transport
CRN80_RS25725	COG4166	transmembrane transport
CRN80_RS25730	COG4174	ABC transporter (Permease)
CRN80_RS25735	COG4239	(ABC) transporter, permease
CRN80_RS25740	COG4172	Belongs to the ABC transporter superfamily
CRN80_RS25775	COG0596	Alpha beta hydrolase
CRN80_RS25785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CRN80_RS25790	COG0529	Catalyzes the synthesis of activated sulfate
CRN80_RS25800	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS25810	COG0583	DNA-binding transcription factor activity
CRN80_RS25815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN80_RS25825	COG0174	glutamine synthetase
CRN80_RS25840	COG2814	Major facilitator Superfamily
CRN80_RS25850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN80_RS25870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS25875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN80_RS25880	COG3209	COG3209 Rhs family protein
CRN80_RS25895	COG3706	GGDEF domain
CRN80_RS25900	COG1280	lysine exporter protein (LysE YggA)
CRN80_RS25915	COG2188	Transcriptional regulator
CRN80_RS25920	COG1522	sequence-specific DNA binding
CRN80_RS25940	COG0475	glutathione-regulated potassium exporter activity
CRN80_RS25940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CRN80_RS26020	COG3321	synthase
CRN80_RS26020	COG0604	alcohol dehydrogenase
CRN80_RS26020	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS26025	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS26035	COG1309	transcriptional regulator
CRN80_RS26055	COG1968	undecaprenyl-diphosphatase activity
CRN80_RS26095	COG0673	inositol 2-dehydrogenase activity
CRN80_RS26110	COG0625	glutathione transferase activity
CRN80_RS26115	COG2957	Belongs to the agmatine deiminase family
CRN80_RS26135	COG0583	DNA-binding transcription factor activity
CRN80_RS26160	COG1172	Belongs to the binding-protein-dependent transport system permease family
CRN80_RS26165	COG1129	ABC transporter
CRN80_RS26170	COG1879	ABC-type sugar transport system periplasmic component
CRN80_RS26180	COG1012	belongs to the aldehyde dehydrogenase family
CRN80_RS26220	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS26225	COG0640	Transcriptional regulator
CRN80_RS26235	COG2199	diguanylate cyclase activity
CRN80_RS26245	COG3781	membrane
CRN80_RS26265	COG2207	Transcriptional regulator
CRN80_RS26265	COG1609	Transcriptional regulator
CRN80_RS26280	COG2115	Belongs to the xylose isomerase family
CRN80_RS26285	COG4213	ABC transporter substrate-binding protein
CRN80_RS26290	COG1129	ABC transporter
CRN80_RS26295	COG4214	carbohydrate transport
CRN80_RS26320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS26335	COG4774	siderophore transport
CRN80_RS26340	COG2814	Major facilitator Superfamily
CRN80_RS26345	COG1595	DNA-templated transcription, initiation
CRN80_RS26350	COG3712	iron ion homeostasis
CRN80_RS26355	COG4774	siderophore transport
CRN80_RS26365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN80_RS26410	COG2323	membrane
CRN80_RS26435	COG3706	GGDEF domain
CRN80_RS26435	COG5001	Diguanylate cyclase
CRN80_RS26435	COG2203	Gaf domain
CRN80_RS26435	COG4251	negative regulation of phosphorylation
CRN80_RS26480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRN80_RS26490	COG1845	cytochrome c oxidase, subunit III
CRN80_RS26505	COG4191	Histidine kinase
CRN80_RS26505	COG0784	Response regulator, receiver
CRN80_RS26510	COG3546	catalase activity
CRN80_RS26535	COG3121	Chaperone
CRN80_RS26545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS26545	COG2205	protein histidine kinase activity
CRN80_RS26550	COG0784	Response regulator, receiver
CRN80_RS26550	COG2205	protein histidine kinase activity
CRN80_RS26555	COG2197	response regulator
CRN80_RS26565	COG3706	GGDEF domain
CRN80_RS26565	COG5001	Diguanylate cyclase
CRN80_RS26565	COG2203	Gaf domain
CRN80_RS26565	COG4251	negative regulation of phosphorylation
CRN80_RS26590	COG1546	Belongs to the CinA family
CRN80_RS26620	COG4221	oxidoreductase activity
CRN80_RS26640	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS26670	COG4221	oxidoreductase activity
CRN80_RS26675	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS26680	COG1309	transcriptional regulator
CRN80_RS26685	COG1301	dicarboxylic acid transport
CRN80_RS26695	COG0583	DNA-binding transcription factor activity
CRN80_RS26750	COG2207	Transcriptional regulator
CRN80_RS26895	COG0322	excinuclease ABC activity
CRN80_RS26900	COG2197	response regulator
CRN80_RS26930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CRN80_RS26945	COG2197	response regulator
CRN80_RS26955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CRN80_RS26995	COG2814	Major facilitator Superfamily
CRN80_RS27010	COG0174	glutamine synthetase
CRN80_RS27045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRN80_RS27050	COG0517	IMP dehydrogenase activity
CRN80_RS27055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CRN80_RS27070	COG0583	DNA-binding transcription factor activity
CRN80_RS27075	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRN80_RS27105	COG3209	COG3209 Rhs family protein
CRN80_RS27115	COG0113	porphobilinogen synthase activity
CRN80_RS27120	COG0384	phenazine biosynthesis protein PhzF
CRN80_RS27125	COG0625	glutathione transferase activity
CRN80_RS27135	COG0701	Predicted permease
CRN80_RS27140	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CRN80_RS27145	COG0709	Synthesizes selenophosphate from selenide and ATP
CRN80_RS27150	COG1253	flavin adenine dinucleotide binding
CRN80_RS27160	COG0583	DNA-binding transcription factor activity
CRN80_RS27170	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CRN80_RS27185	COG3132	Protein of unknown function, DUF480
CRN80_RS27200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRN80_RS27220	COG0628	permease
CRN80_RS27225	COG0826	peptidase U32
CRN80_RS27240	COG2056	Na+-H+ antiporter family
CRN80_RS27245	COG0840	transmembrane signaling receptor activity
CRN80_RS27275	COG0720	synthase
CRN80_RS27280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CRN80_RS27285	COG0402	S-adenosylhomocysteine deaminase activity
CRN80_RS27290	COG3675	Pfam Lipase (class 3)
CRN80_RS27310	COG2223	nitrite transmembrane transporter activity
CRN80_RS27335	COG4772	TonB-dependent receptor
CRN80_RS27345	COG1595	DNA-templated transcription, initiation
CRN80_RS27355	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS27360	COG3387	PFAM Glycoside hydrolase 15-related
CRN80_RS27365	COG0596	Alpha beta hydrolase
CRN80_RS27370	COG4977	sequence-specific DNA binding
CRN80_RS27390	COG1280	lysine exporter protein (LysE YggA)
CRN80_RS27405	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CRN80_RS27405	COG0662	Cupin 2, conserved barrel domain protein
CRN80_RS27435	COG0438	transferase activity, transferring glycosyl groups
CRN80_RS27455	COG0728	peptidoglycan biosynthetic process
CRN80_RS27470	COG0417	DNA replication proofreading
CRN80_RS27490	COG0768	penicillin binding
CRN80_RS27525	COG5006	permease, DMT superfamily
CRN80_RS27535	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS27560	COG3829	transcription factor binding
CRN80_RS27590	COG1181	Belongs to the D-alanine--D-alanine ligase family
CRN80_RS27595	COG1509	lysine 2,3-aminomutase activity
CRN80_RS27625	COG1121	(ABC) transporter
CRN80_RS27630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN80_RS27655	COG1176	ABC-type spermidine putrescine transport system, permease component I
CRN80_RS27665	COG3842	ATPase activity
CRN80_RS27680	COG2200	EAL domain
CRN80_RS27715	COG0545	Peptidyl-prolyl cis-trans isomerase
CRN80_RS27720	COG2010	Cytochrome c
CRN80_RS27750	COG2974	May be involved in recombination
CRN80_RS27755	COG0385	Bile acid
CRN80_RS27760	COG2076	Multidrug Resistance protein
CRN80_RS27765	COG0477	Major facilitator Superfamily
CRN80_RS27785	COG0842	Transport permease protein
CRN80_RS27790	COG1131	(ABC) transporter
CRN80_RS27795	COG0625	glutathione transferase activity
CRN80_RS27820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CRN80_RS27825	COG3540	Alkaline phosphatase
CRN80_RS27850	COG0811	peptide transport
CRN80_RS27865	COG3217	Mosc domain protein beta barrel domain protein
CRN80_RS27865	COG0633	Ferredoxin
CRN80_RS27880	COG0786	glutamate:sodium symporter activity
CRN80_RS27900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CRN80_RS27905	COG2197	response regulator
CRN80_RS27935	COG2267	carboxylic ester hydrolase activity
CRN80_RS27940	COG0840	transmembrane signaling receptor activity
CRN80_RS27955	COG2130	NADP-dependent
CRN80_RS27960	COG0284	orotidine-5'-phosphate decarboxylase activity
CRN80_RS27970	COG2205	protein histidine kinase activity
CRN80_RS27980	COG0628	permease
CRN80_RS28005	COG1022	Amp-dependent synthetase and ligase
CRN80_RS28015	COG2062	phosphohistidine phosphatase, SixA
CRN80_RS28025	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CRN80_RS28030	COG4771	TonB-dependent receptor
CRN80_RS28040	COG5002	protein histidine kinase activity
CRN80_RS28040	COG0784	Response regulator, receiver
CRN80_RS28040	COG2205	protein histidine kinase activity
CRN80_RS28045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CRN80_RS28075	COG1741	Belongs to the pirin family
CRN80_RS28085	COG0326	Molecular chaperone. Has ATPase activity
CRN80_RS28120	COG0045	succinate-CoA ligase (ADP-forming) activity
CRN80_RS28125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN80_RS28140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CRN80_RS28145	COG1053	succinate dehydrogenase
CRN80_RS28150	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CRN80_RS28155	COG2009	succinate dehydrogenase
CRN80_RS28165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRN80_RS28170	COG3162	membrane
CRN80_RS28175	COG2113	Glycine betaine
CRN80_RS28200	COG2853	Lipoprotein
CRN80_RS28205	COG2354	Protein conserved in bacteria
CRN80_RS28210	COG1309	transcriptional regulator
CRN80_RS28225	COG3960	tartronate-semialdehyde synthase activity
CRN80_RS28230	COG3622	Belongs to the hyi family
CRN80_RS28235	COG2084	Dehydrogenase
CRN80_RS28250	COG0469	pyruvate kinase activity
CRN80_RS28260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRN80_RS28275	COG2814	Major facilitator Superfamily
CRN80_RS28285	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CRN80_RS28290	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CRN80_RS28295	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CRN80_RS28305	COG4235	cytochrome complex assembly
CRN80_RS28310	COG3088	subunit of a heme lyase
CRN80_RS28320	COG1138	Cytochrome C-type biogenesis protein
CRN80_RS28325	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CRN80_RS28345	COG4133	protoheme IX ABC transporter activity
CRN80_RS28355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CRN80_RS28370	COG0303	'Molybdopterin
CRN80_RS28375	COG0521	Mo-molybdopterin cofactor biosynthetic process
CRN80_RS28380	COG0746	molybdenum cofactor guanylyltransferase activity
CRN80_RS28390	COG0564	pseudouridine synthase activity
CRN80_RS28415	COG0004	ammonium transporteR
CRN80_RS28445	COG2197	response regulator
CRN80_RS28450	COG2205	protein histidine kinase activity
CRN80_RS28450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN80_RS28455	COG1956	GAF domain-containing protein
CRN80_RS28465	COG0784	Response regulator, receiver
CRN80_RS28465	COG2205	protein histidine kinase activity
CRN80_RS28465	COG5002	protein histidine kinase activity
CRN80_RS28470	COG0386	Belongs to the glutathione peroxidase family
CRN80_RS28475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CRN80_RS28480	COG0436	Aminotransferase
CRN80_RS28485	COG0501	Belongs to the peptidase M48B family
CRN80_RS28490	COG0500	methyltransferase
CRN80_RS28495	COG3384	dioxygenase
CRN80_RS28520	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CRN80_RS28525	COG3214	Protein conserved in bacteria
CRN80_RS28545	COG0583	DNA-binding transcription factor activity
CRN80_RS28550	COG1846	Transcriptional regulator
CRN80_RS28560	COG1764	response to oxidative stress
CRN80_RS28565	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CRN80_RS28580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN80_RS28595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CRN80_RS28630	COG1376	ErfK ybiS ycfS ynhG family protein
CRN80_RS28645	COG4181	ATPase activity
CRN80_RS28650	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CRN80_RS28655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN80_RS28665	COG1131	(ABC) transporter
CRN80_RS28690	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CRN80_RS28695	COG0084	hydrolase, TatD family'
CRN80_RS28705	COG3209	COG3209 Rhs family protein
CRN80_RS28740	COG0745	RESPONSE REGULATOR receiver
CRN80_RS28745	COG2205	protein histidine kinase activity
CRN80_RS28750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CRN80_RS28760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CRN80_RS28795	COG1555	photosystem II stabilization
CRN80_RS28800	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRN80_RS28805	COG0110	maltose O-acetyltransferase activity
CRN80_RS28810	COG1086	Polysaccharide biosynthesis protein
CRN80_RS28815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CRN80_RS28815	COG2755	lipolytic protein G-D-S-L family
CRN80_RS28820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRN80_RS28850	COG2244	polysaccharide biosynthetic process
CRN80_RS28870	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CRN80_RS28885	COG0776	regulation of translation
CRN80_RS28900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CRN80_RS28905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CRN80_RS28910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN80_RS28920	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CRN80_RS28930	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CRN80_RS28935	COG0402	S-adenosylhomocysteine deaminase activity
CRN80_RS28940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CRN80_RS28945	COG0546	phosphoglycolate phosphatase activity
CRN80_RS28950	COG1028	Short-chain dehydrogenase reductase Sdr
CRN80_RS28955	COG0747	negative chemotaxis
CRN80_RS28965	COG0444	Belongs to the ABC transporter superfamily
CRN80_RS28970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN80_RS28980	COG0596	Alpha beta hydrolase
CRN80_RS28985	COG2197	response regulator
CRN80_RS28990	COG2267	carboxylic ester hydrolase activity
CRN80_RS28995	COG2233	PERMEase
CRN80_RS29005	COG2814	Major facilitator Superfamily
CRN80_RS29020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CRN80_RS29025	COG0583	DNA-binding transcription factor activity
CRN80_RS29035	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CRN80_RS29045	COG1611	Belongs to the LOG family
CRN80_RS29070	COG0583	DNA-binding transcription factor activity
CRN80_RS29075	COG0579	oxidoreductase
CRN80_RS29080	COG2814	Major facilitator Superfamily
CRN80_RS29105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN80_RS29115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CRN80_RS29125	COG2204	response regulator
CRN80_RS29140	COG2853	Lipoprotein
CRN80_RS29155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CRN80_RS29155	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CRN80_RS29180	COG4591	ABC-type transport system involved in lipoprotein release permease component
CRN80_RS29185	COG1136	(ABC) transporter
CRN80_RS29190	COG4591	ABC-type transport system involved in lipoprotein release permease component
CRN80_RS29200	COG0584	glycerophosphoryl diester phosphodiesterase
CRN80_RS29205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN80_RS29220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CRN80_RS29230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRN80_RS29235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRN80_RS29290	COG0183	Belongs to the thiolase family
CRN80_RS29295	COG1250	3-hydroxyacyl-CoA dehydrogenase
CRN80_RS29295	COG1024	Enoyl-CoA hydratase
CRN80_RS29310	COG0589	response to stress
CRN80_RS29315	COG0488	(ABC) transporter
CRN80_RS29320	COG0741	lytic transglycosylase activity
CRN80_RS29330	COG1132	(ABC) transporter
CRN80_RS29335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN80_RS29345	COG0425	Belongs to the sulfur carrier protein TusA family
CRN80_RS29350	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CRN80_RS29365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRN80_RS29375	COG0542	response to heat
CRN80_RS29385	COG1984	allophanate hydrolase subunit 2
CRN80_RS29390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CRN80_RS29395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CRN80_RS29400	COG0583	DNA-binding transcription factor activity
CRN80_RS29410	COG0121	glutamine amidotransferase
CRN80_RS29420	COG1770	oligopeptidase
CRN80_RS29455	COG2983	Belongs to the UPF0260 family
CRN80_RS29465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN80_RS29470	COG3100	YcgL domain-containing protein
CRN80_RS29485	COG0174	glutamine synthetase
CRN80_RS29495	COG0583	DNA-binding transcription factor activity
CRN80_RS29505	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CRN80_RS29535	COG0583	DNA-binding transcription factor activity
CRN80_RS29545	COG2910	NAD(P)H-binding
CRN80_RS29560	COG2807	transmembrane transport
CRN80_RS29590	COG0583	DNA-binding transcription factor activity
CRN80_RS29605	COG0477	Major facilitator Superfamily
CRN80_RS29610	COG0583	DNA-binding transcription factor activity
CRN80_RS29615	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CRN80_RS29645	COG2026	Addiction module toxin, RelE StbE family
CRN80_RS29655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CRN80_RS29660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CRN80_RS29665	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CRN80_RS29670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN80_RS29680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CRN80_RS29690	COG0425	Belongs to the sulfur carrier protein TusA family
CRN80_RS29700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN80_RS29730	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CRN80_RS29785	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CRN80_RS29815	COG2267	carboxylic ester hydrolase activity
CRN80_RS29835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRN80_RS29875	COG1454	alcohol dehydrogenase
CRN80_RS29885	COG1396	sequence-specific DNA binding
CRN80_RS29890	COG0235	Class ii aldolase
CRN80_RS29895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN80_RS29910	COG1629	transport
CRN80_RS29945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN80_RS29960	COG0154	amidase activity
CRN80_RS29970	COG1473	amidohydrolase
CRN80_RS30015	COG2814	Major facilitator Superfamily
CRN80_RS30020	COG1902	pentaerythritol trinitrate reductase activity
CRN80_RS30035	COG1309	transcriptional regulator
CRN80_RS30040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN80_RS30065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CRN80_RS30070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CRN80_RS30080	COG0477	Major facilitator Superfamily
CRN80_RS30085	COG3485	protocatechuate 3,4-dioxygenase
CRN80_RS30090	COG3485	protocatechuate 3,4-dioxygenase
CRN80_RS30095	COG0183	Belongs to the thiolase family
CRN80_RS30100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CRN80_RS30105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRN80_RS30110	COG2814	Major facilitator Superfamily
CRN80_RS30115	COG1414	Transcriptional regulator
CRN80_RS30125	COG0306	phosphate transporter
CRN80_RS30130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CRN80_RS30140	COG0084	hydrolase, TatD family'
CRN80_RS30150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CRN80_RS30155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CRN80_RS30165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRN80_RS30170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRN80_RS30185	COG0416	fatty acid biosynthetic process
CRN80_RS30190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CRN80_RS30200	COG0424	maF-like protein
CRN80_RS30205	COG0616	signal peptide processing
CRN80_RS30205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CRN80_RS30210	COG0546	phosphoglycolate phosphatase activity
CRN80_RS30220	COG1530	ribonuclease E activity
CRN80_RS30230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CRN80_RS30235	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CRN80_RS30235	COG3608	succinylglutamate desuccinylase aspartoacylase
CRN80_RS30240	COG1301	dicarboxylic acid transport
CRN80_RS30245	COG4977	sequence-specific DNA binding
CRN80_RS30245	COG1917	Cupin 2, conserved barrel domain protein
CRN80_RS30255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CRN80_RS30265	COG0259	pyridoxamine-phosphate oxidase activity
CRN80_RS30275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding