locus-tag	class	description
AWU82_RS00015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWU82_RS00030	COG2031	fatty acid transporter
AWU82_RS00035	COG0443	Heat shock 70 kDa protein
AWU82_RS00055	COG0288	reversible hydration of carbon dioxide
AWU82_RS00065	COG0456	acetyltransferase
AWU82_RS00090	COG3008	intermembrane lipid transfer
AWU82_RS00095	COG2995	paraquat-inducible protein a
AWU82_RS00100	COG2995	paraquat-inducible protein a
AWU82_RS00110	COG5006	permease, DMT superfamily
AWU82_RS00125	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS00140	COG0583	DNA-binding transcription factor activity
AWU82_RS00165	COG0431	NADPH-dependent FMN reductase
AWU82_RS00170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWU82_RS00180	COG3829	transcription factor binding
AWU82_RS00200	COG0596	Alpha beta hydrolase
AWU82_RS00235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWU82_RS00260	COG0642	Histidine kinase
AWU82_RS00280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWU82_RS00330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWU82_RS00335	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS00340	COG1024	Enoyl-CoA hydratase
AWU82_RS00340	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWU82_RS00365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWU82_RS00370	COG0778	Nitroreductase
AWU82_RS00375	COG0642	Histidine kinase
AWU82_RS00385	COG0745	RESPONSE REGULATOR receiver
AWU82_RS00395	COG2350	Protein conserved in bacteria
AWU82_RS00400	COG2917	probably involved in intracellular septation
AWU82_RS00410	COG0009	L-threonylcarbamoyladenylate synthase
AWU82_RS00420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AWU82_RS00435	COG1113	amino acid transport
AWU82_RS00460	COG2154	pterin-4-alpha-carbinolamine dehydratase
AWU82_RS00475	COG4787	bacterial-type flagellum-dependent cell motility
AWU82_RS00485	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AWU82_RS00490	COG1706	bacterial-type flagellum-dependent cell motility
AWU82_RS00500	COG1256	bacterial-type flagellum assembly
AWU82_RS00510	COG1216	Glycosyl transferase, family 2
AWU82_RS00510	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS00530	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AWU82_RS00540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWU82_RS00555	COG1216	Glycosyl transferase, family 2
AWU82_RS00555	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS00560	COG1086	Polysaccharide biosynthesis protein
AWU82_RS00575	COG1083	cytidylyl-transferase
AWU82_RS00585	COG2089	acid synthase
AWU82_RS00590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWU82_RS00645	COG1677	Flagellar hook-basal body complex protein FliE
AWU82_RS00670	COG2882	bacterial-type flagellum organization
AWU82_RS00680	COG0745	RESPONSE REGULATOR receiver
AWU82_RS00695	COG1580	Controls the rotational direction of flagella during chemotaxis
AWU82_RS00730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWU82_RS00780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AWU82_RS00785	COG2198	Histidine kinase
AWU82_RS00785	COG0643	Histidine kinase
AWU82_RS00785	COG0784	Response regulator, receiver
AWU82_RS00790	COG2201	protein-glutamate methylesterase activity
AWU82_RS00795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWU82_RS00805	COG1192	Involved in chromosome partitioning
AWU82_RS00815	COG0835	chemotaxis
AWU82_RS00835	COG4133	protoheme IX ABC transporter activity
AWU82_RS00855	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AWU82_RS00860	COG1138	Cytochrome C-type biogenesis protein
AWU82_RS00870	COG3088	subunit of a heme lyase
AWU82_RS00885	COG3311	Transcriptional regulator
AWU82_RS00890	COG1598	PFAM Uncharacterised protein family UPF0150
AWU82_RS00895	COG2814	Major facilitator Superfamily
AWU82_RS00905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWU82_RS00910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWU82_RS00915	COG4413	Urea transporter
AWU82_RS00920	COG0469	pyruvate kinase activity
AWU82_RS00930	COG2084	Dehydrogenase
AWU82_RS00935	COG3622	Belongs to the hyi family
AWU82_RS00940	COG3960	tartronate-semialdehyde synthase activity
AWU82_RS00955	COG1309	transcriptional regulator
AWU82_RS00960	COG2354	Protein conserved in bacteria
AWU82_RS00965	COG2853	Lipoprotein
AWU82_RS00990	COG2113	Glycine betaine
AWU82_RS00995	COG3162	membrane
AWU82_RS01000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWU82_RS01010	COG2009	succinate dehydrogenase
AWU82_RS01015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AWU82_RS01020	COG1053	succinate dehydrogenase
AWU82_RS01025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWU82_RS01040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWU82_RS01045	COG0045	succinate-CoA ligase (ADP-forming) activity
AWU82_RS01085	COG0326	Molecular chaperone. Has ATPase activity
AWU82_RS01095	COG1741	Belongs to the pirin family
AWU82_RS01120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWU82_RS01125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWU82_RS01135	COG0628	permease
AWU82_RS01140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWU82_RS01145	COG0791	NLP P60 protein
AWU82_RS01150	COG0791	NLP P60 protein
AWU82_RS01170	COG1797	cobyrinic acid a,c-diamide synthase activity
AWU82_RS01175	COG0778	Nitroreductase
AWU82_RS01190	COG1492	cobalamin metabolic process
AWU82_RS01200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AWU82_RS01210	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AWU82_RS01270	COG0662	Cupin 2, conserved barrel domain protein
AWU82_RS01285	COG2076	Multidrug Resistance protein
AWU82_RS01290	COG0385	Bile acid
AWU82_RS01295	COG2974	May be involved in recombination
AWU82_RS01320	COG0753	catalase activity
AWU82_RS01325	COG2010	Cytochrome c
AWU82_RS01330	COG0545	Peptidyl-prolyl cis-trans isomerase
AWU82_RS01355	COG3209	COG3209 Rhs family protein
AWU82_RS01355	COG3209	COG3209 Rhs family protein
AWU82_RS01365	COG2200	EAL domain
AWU82_RS01375	COG4221	oxidoreductase activity
AWU82_RS01375	COG3321	synthase
AWU82_RS01375	COG0604	alcohol dehydrogenase
AWU82_RS01375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWU82_RS01395	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS01415	COG0668	transmembrane transport
AWU82_RS01420	COG1362	aminopeptidase activity
AWU82_RS01425	COG0564	pseudouridine synthase activity
AWU82_RS01430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AWU82_RS01435	COG2894	cell division
AWU82_RS01440	COG0850	regulation of cytokinetic process
AWU82_RS01445	COG1560	Kdo2-lipid A biosynthetic process
AWU82_RS01465	COG2233	PERMEase
AWU82_RS01475	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AWU82_RS01480	COG4266	Belongs to the allantoicase family
AWU82_RS01510	COG2252	PERMEase
AWU82_RS01520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWU82_RS01530	COG0302	gtp cyclohydrolase
AWU82_RS01535	COG2840	Smr protein MutS2
AWU82_RS01565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWU82_RS01575	COG0235	Class ii aldolase
AWU82_RS01580	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWU82_RS01585	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWU82_RS01595	COG0318	PFAM AMP-dependent synthetase and ligase
AWU82_RS01615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWU82_RS01635	COG2308	Evidence 4 Homologs of previously reported genes of
AWU82_RS01645	COG1305	Transglutaminase-like
AWU82_RS01655	COG0183	Belongs to the thiolase family
AWU82_RS01660	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWU82_RS01660	COG1024	Enoyl-CoA hydratase
AWU82_RS01665	COG0519	Catalyzes the synthesis of GMP from XMP
AWU82_RS01665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWU82_RS01670	COG0598	Magnesium transport protein CorA
AWU82_RS01675	COG0204	Acyl-transferase
AWU82_RS01690	COG0393	Putative heavy-metal-binding
AWU82_RS01720	COG3209	COG3209 Rhs family protein
AWU82_RS01720	COG3209	COG3209 Rhs family protein
AWU82_RS01725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWU82_RS01730	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS01745	COG1953	Uracil, thiamine, allantoin
AWU82_RS01755	COG0560	Phosphoserine phosphatase
AWU82_RS01765	COG0189	ligase activity
AWU82_RS01775	COG0189	ligase activity
AWU82_RS01775	COG4067	protein conserved in archaea
AWU82_RS01780	COG1802	Transcriptional regulator
AWU82_RS01790	COG0372	Belongs to the citrate synthase family
AWU82_RS01805	COG2079	MmgE PrpD family protein
AWU82_RS01810	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWU82_RS01825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AWU82_RS01840	COG0668	transmembrane transport
AWU82_RS01855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWU82_RS01860	COG0243	molybdopterin cofactor binding
AWU82_RS01865	COG2146	nitrite reductase [NAD(P)H] activity
AWU82_RS01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWU82_RS01880	COG2223	nitrite transmembrane transporter activity
AWU82_RS01885	COG3707	response regulator
AWU82_RS01890	COG1116	anion transmembrane transporter activity
AWU82_RS01890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWU82_RS01895	COG0167	dihydroorotate dehydrogenase activity
AWU82_RS01900	COG0116	Belongs to the methyltransferase superfamily
AWU82_RS01900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWU82_RS01910	COG2027	D-alanyl-D-alanine carboxypeptidase
AWU82_RS01915	COG3171	Protein conserved in bacteria
AWU82_RS01920	COG3135	benzoate transporter
AWU82_RS01925	COG1802	Transcriptional regulator
AWU82_RS01930	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS01960	COG3115	cell septum assembly
AWU82_RS01965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWU82_RS01990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWU82_RS01995	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWU82_RS02000	COG2130	NADP-dependent
AWU82_RS02005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWU82_RS02010	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS02015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWU82_RS02020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWU82_RS02055	COG0348	domain, Protein
AWU82_RS02070	COG2010	Cytochrome c
AWU82_RS02085	COG3278	Belongs to the heme-copper respiratory oxidase family
AWU82_RS02090	COG2010	Cytochrome c
AWU82_RS02105	COG3278	Belongs to the heme-copper respiratory oxidase family
AWU82_RS02120	COG1132	(ABC) transporter
AWU82_RS02130	COG0840	transmembrane signaling receptor activity
AWU82_RS02145	COG4977	sequence-specific DNA binding
AWU82_RS02150	COG2267	carboxylic ester hydrolase activity
AWU82_RS02155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWU82_RS02165	COG3387	PFAM Glycoside hydrolase 15-related
AWU82_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS02205	COG0657	acetylesterase activity
AWU82_RS02210	COG4774	siderophore transport
AWU82_RS02245	COG0577	efflux transmembrane transporter activity
AWU82_RS02245	COG1136	(ABC) transporter
AWU82_RS02250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS02265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWU82_RS02285	COG2205	protein histidine kinase activity
AWU82_RS02285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS02290	COG0656	L-ascorbic acid biosynthetic process
AWU82_RS02305	COG0708	Exodeoxyribonuclease III
AWU82_RS02320	COG2233	PERMEase
AWU82_RS02345	COG0556	nucleotide-excision repair
AWU82_RS02360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWU82_RS02390	COG0596	Alpha beta hydrolase
AWU82_RS02400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWU82_RS02415	COG2214	Heat shock protein DnaJ domain protein
AWU82_RS02420	COG0443	Heat shock 70 kDa protein
AWU82_RS02435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWU82_RS02440	COG0066	3-isopropylmalate dehydratase activity
AWU82_RS02445	COG2226	methyltransferase
AWU82_RS02450	COG0473	3-isopropylmalate dehydrogenase activity
AWU82_RS02475	COG0135	phosphoribosylanthranilate isomerase activity
AWU82_RS02480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWU82_RS02485	COG0285	dihydrofolate synthase activity
AWU82_RS02495	COG1286	toxin biosynthetic process
AWU82_RS02530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AWU82_RS02540	COG2010	Cytochrome c
AWU82_RS02545	COG3608	succinylglutamate desuccinylase aspartoacylase
AWU82_RS02545	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AWU82_RS02550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS02600	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWU82_RS02640	COG1129	ABC transporter
AWU82_RS02645	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWU82_RS02650	COG1609	Transcriptional regulator
AWU82_RS02655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWU82_RS02660	COG1869	D-ribose catabolic process
AWU82_RS02685	COG1278	Cold shock
AWU82_RS02695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWU82_RS02700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWU82_RS02705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWU82_RS02710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWU82_RS02715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWU82_RS02720	COG0072	phenylalanine-tRNA ligase activity
AWU82_RS02725	COG0776	regulation of translation
AWU82_RS02755	COG4650	regulator
AWU82_RS02765	COG1690	Belongs to the RtcB family
AWU82_RS02770	COG3541	Predicted nucleotidyltransferase
AWU82_RS02775	COG0430	RNA-3'-phosphate cyclase activity
AWU82_RS02795	COG0604	alcohol dehydrogenase
AWU82_RS02795	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS02795	COG3321	synthase
AWU82_RS02805	COG0583	DNA-binding transcription factor activity
AWU82_RS02810	COG1741	Belongs to the pirin family
AWU82_RS02840	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AWU82_RS02865	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AWU82_RS02870	COG1335	isochorismatase
AWU82_RS02885	COG0583	DNA-binding transcription factor activity
AWU82_RS02895	COG1459	type II secretion system
AWU82_RS02905	COG0741	lytic transglycosylase activity
AWU82_RS02905	COG0739	heme binding
AWU82_RS02905	COG1196	nuclear chromosome segregation
AWU82_RS02935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWU82_RS02970	COG4796	Type ii and iii secretion system protein
AWU82_RS03000	COG1462	curli production assembly transport component CsgG
AWU82_RS03050	COG5002	protein histidine kinase activity
AWU82_RS03065	COG4191	Histidine kinase
AWU82_RS03070	COG2204	response regulator
AWU82_RS03115	COG0726	polysaccharide deacetylase
AWU82_RS03210	COG2720	vancomycin resistance protein
AWU82_RS03220	COG3209	COG3209 Rhs family protein
AWU82_RS03230	COG3209	COG3209 Rhs family protein
AWU82_RS03240	COG3209	COG3209 Rhs family protein
AWU82_RS03270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWU82_RS03270	COG0457	Tetratricopeptide repeat
AWU82_RS03285	COG2201	protein-glutamate methylesterase activity
AWU82_RS03290	COG5001	Diguanylate cyclase
AWU82_RS03290	COG4251	negative regulation of phosphorylation
AWU82_RS03290	COG3706	GGDEF domain
AWU82_RS03290	COG2203	Gaf domain
AWU82_RS03300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AWU82_RS03305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWU82_RS03325	COG1073	alpha beta
AWU82_RS03350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AWU82_RS03355	COG0563	adenylate kinase activity
AWU82_RS03360	COG1214	PFAM Peptidase M22, glycoprotease
AWU82_RS03370	COG1801	Protein of unknown function DUF72
AWU82_RS03390	COG0742	ribosomal rna small subunit methyltransferase
AWU82_RS03400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS03425	COG2937	Belongs to the GPAT DAPAT family
AWU82_RS03440	COG2226	methyltransferase
AWU82_RS03445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWU82_RS03455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWU82_RS03465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWU82_RS03470	COG2171	N-acyltransferase activity
AWU82_RS03475	COG1393	Belongs to the ArsC family
AWU82_RS03480	COG0025	NhaP-type Na H and K H
AWU82_RS03535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWU82_RS03550	COG0653	protein targeting
AWU82_RS03595	COG0025	NhaP-type Na H and K H
AWU82_RS03635	COG0436	Aminotransferase
AWU82_RS03640	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AWU82_RS03645	COG0024	Methionine aminopeptidase
AWU82_RS03650	COG0052	Belongs to the universal ribosomal protein uS2 family
AWU82_RS03655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWU82_RS03660	COG0528	UMP kinase activity
AWU82_RS03665	COG0233	cytoplasmic translational termination
AWU82_RS03670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWU82_RS03680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWU82_RS03700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWU82_RS03705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWU82_RS03710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWU82_RS03715	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWU82_RS03720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWU82_RS03725	COG0587	DNA-directed DNA polymerase activity
AWU82_RS03730	COG0825	malonyl-CoA metabolic process
AWU82_RS03735	COG0037	tRNA processing
AWU82_RS03740	COG0504	CTP synthase activity
AWU82_RS03745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AWU82_RS03750	COG0148	phosphopyruvate hydratase activity
AWU82_RS03760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWU82_RS03770	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AWU82_RS03775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AWU82_RS03780	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWU82_RS03785	COG0585	pseudouridine synthase activity
AWU82_RS03790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWU82_RS03795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWU82_RS03815	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWU82_RS03930	COG4386	tail sheath protein
AWU82_RS03965	COG4381	Mu-like prophage protein gp46
AWU82_RS04020	COG3179	chitinase
AWU82_RS04030	COG1546	Belongs to the CinA family
AWU82_RS04035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWU82_RS04040	COG2137	regulation of response to DNA damage stimulus
AWU82_RS04060	COG3148	PFAM DTW domain containing protein
AWU82_RS04075	COG0583	DNA-binding transcription factor activity
AWU82_RS04095	COG4807	Protein conserved in bacteria
AWU82_RS04110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWU82_RS04115	COG3158	transport of potassium into the cell
AWU82_RS04140	COG2211	Major facilitator Superfamily
AWU82_RS04145	COG0442	prolyl-tRNA aminoacylation
AWU82_RS04155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWU82_RS04195	COG3830	Belongs to the UPF0237 family
AWU82_RS04195	COG0560	Phosphoserine phosphatase
AWU82_RS04210	COG0688	phosphatidylethanolamine metabolic process
AWU82_RS04250	COG1162	GTPase activity
AWU82_RS04255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AWU82_RS04260	COG2860	membrane
AWU82_RS04290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWU82_RS04290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWU82_RS04295	COG0802	atpase or kinase
AWU82_RS04300	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWU82_RS04305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWU82_RS04310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWU82_RS04315	COG1923	regulation of RNA biosynthetic process
AWU82_RS04320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWU82_RS04325	COG0330	HflC and HflK could
AWU82_RS04330	COG0330	HflC and HflK could
AWU82_RS04335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWU82_RS04340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWU82_RS04350	COG1178	ABC-type Fe3 transport system permease component
AWU82_RS04355	COG1840	ABC-type Fe3 transport system, periplasmic component
AWU82_RS04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWU82_RS04380	COG0360	Binds together with S18 to 16S ribosomal RNA
AWU82_RS04385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWU82_RS04395	COG0359	binds to the 23S rRNA
AWU82_RS04400	COG0305	Participates in initiation and elongation during chromosome replication
AWU82_RS04410	COG1032	radical SAM domain protein
AWU82_RS04420	COG2308	Evidence 4 Homologs of previously reported genes of
AWU82_RS04420	COG2307	Protein conserved in bacteria
AWU82_RS04450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWU82_RS04455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWU82_RS04460	COG0583	DNA-binding transcription factor activity
AWU82_RS04465	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS04470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS04480	COG0559	Belongs to the binding-protein-dependent transport system permease family
AWU82_RS04500	COG4221	oxidoreductase activity
AWU82_RS04520	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWU82_RS04525	COG0830	nickel cation binding
AWU82_RS04530	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWU82_RS04535	COG1309	transcriptional regulator
AWU82_RS04545	COG2982	Protein involved in outer membrane biogenesis
AWU82_RS04555	COG0583	DNA-binding transcription factor activity
AWU82_RS04560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWU82_RS04570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWU82_RS04575	COG0697	spore germination
AWU82_RS04595	COG0443	Heat shock 70 kDa protein
AWU82_RS04600	COG0484	heat shock protein binding
AWU82_RS04605	COG0789	Transcriptional regulator
AWU82_RS04615	COG0804	urea catabolic process
AWU82_RS04620	COG0832	Belongs to the urease beta subunit family
AWU82_RS04635	COG0831	urea catabolic process
AWU82_RS04640	COG0829	nickel cation binding
AWU82_RS04650	COG0411	ABC transporter
AWU82_RS04665	COG0683	leucine binding
AWU82_RS04670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWU82_RS04680	COG1120	ATPase activity
AWU82_RS04720	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AWU82_RS04745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWU82_RS04770	COG2095	MarC family integral membrane protein
AWU82_RS04780	COG0151	Belongs to the GarS family
AWU82_RS04785	COG0138	bifunctional purine biosynthesis protein purh
AWU82_RS04795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWU82_RS04805	COG2264	protein methyltransferase activity
AWU82_RS04870	COG0023	Translation Initiation Factor
AWU82_RS04875	COG1166	arginine decarboxylase activity
AWU82_RS04890	COG0534	Mate efflux family protein
AWU82_RS04905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWU82_RS04975	COG4964	Belongs to the GSP D family
AWU82_RS05005	COG2030	dehydratase
AWU82_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS05015	COG0183	Belongs to the thiolase family
AWU82_RS05020	COG0840	transmembrane signaling receptor activity
AWU82_RS05040	COG2217	Heavy metal translocating P-type atpase
AWU82_RS05050	COG2217	Heavy metal translocating P-type atpase
AWU82_RS05055	COG2814	Major facilitator Superfamily
AWU82_RS05060	COG0604	alcohol dehydrogenase
AWU82_RS05070	COG0583	DNA-binding transcription factor activity
AWU82_RS05080	COG0477	Major facilitator Superfamily
AWU82_RS05085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AWU82_RS05100	COG0387	Pfam Sodium calcium exchanger
AWU82_RS05125	COG1079	Belongs to the binding-protein-dependent transport system permease family
AWU82_RS05130	COG4603	Belongs to the binding-protein-dependent transport system permease family
AWU82_RS05135	COG3845	ABC transporter
AWU82_RS05145	COG1309	transcriptional regulator
AWU82_RS05175	COG0583	DNA-binding transcription factor activity
AWU82_RS05195	COG0427	acetyl-CoA hydrolase
AWU82_RS05230	COG0159	tryptophan synthase activity
AWU82_RS05235	COG0133	tryptophan synthase activity
AWU82_RS05250	COG3360	Dodecin
AWU82_RS05260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWU82_RS05265	COG1764	response to oxidative stress
AWU82_RS05300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWU82_RS05310	COG3121	Chaperone
AWU82_RS05315	COG3188	usher protein
AWU82_RS05325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWU82_RS05335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS05350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS05360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWU82_RS05375	COG0427	acetyl-CoA hydrolase
AWU82_RS05380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWU82_RS05400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWU82_RS05420	COG0583	DNA-binding transcription factor activity
AWU82_RS05425	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS05435	COG0583	DNA-binding transcription factor activity
AWU82_RS05445	COG0247	lactate metabolic process
AWU82_RS05445	COG0277	FAD linked oxidase domain protein
AWU82_RS05450	COG0583	DNA-binding transcription factor activity
AWU82_RS05455	COG4948	Mandelate Racemase Muconate Lactonizing
AWU82_RS05465	COG0583	DNA-binding transcription factor activity
AWU82_RS05475	COG4568	rho-dependent transcription termination
AWU82_RS05495	COG0494	nUDIX hydrolase
AWU82_RS05510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWU82_RS05515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWU82_RS05520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWU82_RS05525	COG2135	peptidase activity
AWU82_RS05555	COG1611	Belongs to the LOG family
AWU82_RS05595	COG2111	Na H antiporter
AWU82_RS05595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWU82_RS05600	COG1006	Multisubunit Na H antiporter MnhC subunit
AWU82_RS05605	COG0651	ATP synthesis coupled electron transport
AWU82_RS05615	COG2212	antiporter activity
AWU82_RS05620	COG1320	monovalent cation:proton antiporter activity
AWU82_RS05635	COG4774	siderophore transport
AWU82_RS05670	COG0840	transmembrane signaling receptor activity
AWU82_RS05685	COG4335	DNA alkylation repair
AWU82_RS05725	COG0640	Transcriptional regulator
AWU82_RS05730	COG0589	response to stress
AWU82_RS05745	COG0589	response to stress
AWU82_RS05760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWU82_RS05765	COG1063	alcohol dehydrogenase
AWU82_RS05775	COG3038	cytochrome b561
AWU82_RS05785	COG1022	Amp-dependent synthetase and ligase
AWU82_RS05830	COG0477	Major facilitator Superfamily
AWU82_RS05845	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWU82_RS05855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWU82_RS05875	COG0583	DNA-binding transcription factor activity
AWU82_RS05880	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWU82_RS05890	COG0288	reversible hydration of carbon dioxide
AWU82_RS05895	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWU82_RS05900	COG2066	Belongs to the glutaminase family
AWU82_RS05910	COG2259	Doxx family
AWU82_RS05960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWU82_RS05965	COG0339	signal peptide processing
AWU82_RS05970	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AWU82_RS05975	COG0339	signal peptide processing
AWU82_RS06010	COG0659	secondary active sulfate transmembrane transporter activity
AWU82_RS06020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWU82_RS06020	COG1565	acr, cog1565
AWU82_RS06025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWU82_RS06030	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AWU82_RS06060	COG0109	protoheme IX farnesyltransferase activity
AWU82_RS06075	COG2011	ABC-type metal ion transport system permease component
AWU82_RS06080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWU82_RS06095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWU82_RS06100	COG1121	(ABC) transporter
AWU82_RS06105	COG0735	belongs to the Fur family
AWU82_RS06110	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AWU82_RS06130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWU82_RS06145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWU82_RS06160	COG3023	N-Acetylmuramoyl-L-alanine amidase
AWU82_RS06165	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AWU82_RS06170	COG5002	protein histidine kinase activity
AWU82_RS06175	COG2204	response regulator
AWU82_RS06190	COG1301	dicarboxylic acid transport
AWU82_RS06195	COG0700	Nucleoside recognition
AWU82_RS06210	COG1127	ABC transporter
AWU82_RS06215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWU82_RS06225	COG0612	Peptidase, M16
AWU82_RS06230	COG1283	sodium-dependent phosphate transmembrane transporter activity
AWU82_RS06235	COG0861	Integral membrane protein TerC family
AWU82_RS06240	COG2851	Citrate transporter
AWU82_RS06265	COG3119	arylsulfatase activity
AWU82_RS06280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWU82_RS06285	COG0408	coproporphyrinogen oxidase activity
AWU82_RS06295	COG0009	L-threonylcarbamoyladenylate synthase
AWU82_RS06300	COG0758	DNA mediated transformation
AWU82_RS06310	COG0242	peptide deformylase activity
AWU82_RS06315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWU82_RS06320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWU82_RS06325	COG0569	domain protein
AWU82_RS06340	COG2818	Glycosylase
AWU82_RS06345	COG0752	glycyl-tRNA synthetase alpha subunit
AWU82_RS06350	COG0751	glycine-tRNA ligase activity
AWU82_RS06355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWU82_RS06365	COG2205	protein histidine kinase activity
AWU82_RS06375	COG0187	DNA topoisomerase II activity
AWU82_RS06380	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWU82_RS06385	COG0592	DNA-directed DNA polymerase activity
AWU82_RS06390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWU82_RS06395	COG0594	ribonuclease P activity
AWU82_RS06400	COG0706	membrane insertase activity
AWU82_RS06405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWU82_RS06410	COG0445	tRNA wobble uridine modification
AWU82_RS06415	COG0357	Ribosomal RNA small subunit methyltransferase G
AWU82_RS06420	COG1192	Involved in chromosome partitioning
AWU82_RS06425	COG1475	DNA binding
AWU82_RS06430	COG3312	ion transport
AWU82_RS06435	COG0356	it plays a direct role in the translocation of protons across the membrane
AWU82_RS06445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWU82_RS06450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWU82_RS06455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWU82_RS06460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWU82_RS06465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWU82_RS06470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWU82_RS06475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWU82_RS06480	COG1349	DNA-binding transcription factor activity
AWU82_RS06485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWU82_RS06490	COG0583	DNA-binding transcription factor activity
AWU82_RS06495	COG0625	glutathione transferase activity
AWU82_RS06500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWU82_RS06500	COG1017	nitric oxide dioxygenase activity
AWU82_RS06510	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS06555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWU82_RS06560	COG2755	lipolytic protein G-D-S-L family
AWU82_RS06560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AWU82_RS06590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWU82_RS06610	COG2217	Heavy metal translocating P-type atpase
AWU82_RS06615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AWU82_RS06620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWU82_RS06630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWU82_RS06640	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWU82_RS06655	COG1469	GTP cyclohydrolase I activity
AWU82_RS06660	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWU82_RS06685	COG0523	cobalamin synthesis protein
AWU82_RS06695	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AWU82_RS06700	COG1607	acyl-coa hydrolase
AWU82_RS06705	COG4651	solute:proton antiporter activity
AWU82_RS06705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWU82_RS06725	COG0210	DNA helicase
AWU82_RS06745	COG0583	DNA-binding transcription factor activity
AWU82_RS06750	COG0439	Biotin carboxylase
AWU82_RS06755	COG0511	ligase activity, forming carbon-carbon bonds
AWU82_RS06755	COG5016	pyruvate
AWU82_RS06830	COG0252	asparaginase activity
AWU82_RS06835	COG1115	amino acid carrier protein
AWU82_RS06840	COG1027	Aspartate ammonia-lyase
AWU82_RS06845	COG0583	DNA-binding transcription factor activity
AWU82_RS06880	COG1607	acyl-coa hydrolase
AWU82_RS06885	COG0477	Major facilitator Superfamily
AWU82_RS06910	COG0573	inorganic phosphate transmembrane transporter activity
AWU82_RS06915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWU82_RS06920	COG0704	Plays a role in the regulation of phosphate uptake
AWU82_RS06930	COG0739	heme binding
AWU82_RS06935	COG1253	flavin adenine dinucleotide binding
AWU82_RS06955	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWU82_RS06960	COG3161	chorismate lyase activity
AWU82_RS07045	COG2204	response regulator
AWU82_RS07085	COG0515	serine threonine protein kinase
AWU82_RS07085	COG2815	serine threonine protein kinase
AWU82_RS07110	COG3755	Protein conserved in bacteria
AWU82_RS07160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWU82_RS07165	COG0583	DNA-binding transcription factor activity
AWU82_RS07175	COG0848	biopolymer transport protein
AWU82_RS07200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWU82_RS07205	COG1758	RNA polymerase activity
AWU82_RS07210	COG0194	GDP metabolic process
AWU82_RS07215	COG1561	YicC-like family, N-terminal region
AWU82_RS07220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AWU82_RS07230	COG0708	Exodeoxyribonuclease III
AWU82_RS07235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWU82_RS07250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWU82_RS07255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWU82_RS07260	COG0756	dUTP diphosphatase activity
AWU82_RS07265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWU82_RS07270	COG2003	Belongs to the UPF0758 family
AWU82_RS07275	COG0747	negative chemotaxis
AWU82_RS07280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWU82_RS07285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWU82_RS07295	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS07305	COG0534	Mate efflux family protein
AWU82_RS07310	COG0583	DNA-binding transcription factor activity
AWU82_RS07320	COG0606	chelatase, subunit chli
AWU82_RS07330	COG3093	addiction module antidote protein HigA
AWU82_RS07345	COG0347	Belongs to the P(II) protein family
AWU82_RS07350	COG0004	ammonium transporteR
AWU82_RS07355	COG0432	Pfam Uncharacterised protein family UPF0047
AWU82_RS07365	COG1011	Hydrolase
AWU82_RS07370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AWU82_RS07380	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWU82_RS07385	COG0019	diaminopimelate decarboxylase activity
AWU82_RS07390	COG1965	Belongs to the frataxin family
AWU82_RS07395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWU82_RS07415	COG0625	glutathione transferase activity
AWU82_RS07420	COG0165	Argininosuccinate lyase
AWU82_RS07430	COG0181	hydroxymethylbilane synthase activity
AWU82_RS07450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AWU82_RS07480	COG0488	(ABC) transporter
AWU82_RS07490	COG1280	lysine exporter protein (LysE YggA)
AWU82_RS07520	COG0672	)-iron permease
AWU82_RS07525	COG1671	Belongs to the UPF0178 family
AWU82_RS07530	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AWU82_RS07540	COG0586	Pfam SNARE associated Golgi protein
AWU82_RS07550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWU82_RS07555	COG0248	Ppx GppA phosphatase
AWU82_RS07560	COG1126	abc transporter atp-binding protein
AWU82_RS07565	COG0765	amino acid transport
AWU82_RS07570	COG0765	amino acid transport
AWU82_RS07575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS07580	COG2186	Transcriptional regulator
AWU82_RS07595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AWU82_RS07595	COG2755	lipolytic protein G-D-S-L family
AWU82_RS07600	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWU82_RS07615	COG2271	Major facilitator Superfamily
AWU82_RS07635	COG0842	Transport permease protein
AWU82_RS07640	COG1129	ABC transporter
AWU82_RS07640	COG0842	Transport permease protein
AWU82_RS07645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS07655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWU82_RS07675	COG3079	Belongs to the UPF0149 family
AWU82_RS07680	COG0006	proline dipeptidase activity
AWU82_RS07685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWU82_RS07695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWU82_RS07705	COG1178	ABC-type Fe3 transport system permease component
AWU82_RS07710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWU82_RS07715	COG0509	glycine decarboxylation via glycine cleavage system
AWU82_RS07720	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWU82_RS07720	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWU82_RS07730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWU82_RS07740	COG1522	sequence-specific DNA binding
AWU82_RS07755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWU82_RS07755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AWU82_RS07760	COG4521	taurine ABC transporter
AWU82_RS07770	COG0450	alkyl hydroperoxide reductase
AWU82_RS07775	COG0431	NADPH-dependent FMN reductase
AWU82_RS07780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWU82_RS07785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWU82_RS07790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWU82_RS07795	COG1116	anion transmembrane transporter activity
AWU82_RS07815	COG0174	glutamine synthetase
AWU82_RS07820	COG0174	glutamine synthetase
AWU82_RS07840	COG3842	ATPase activity
AWU82_RS07845	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS07850	COG1177	transmembrane transport
AWU82_RS07900	COG1683	Conserved Protein
AWU82_RS07905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS07915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWU82_RS07920	COG0277	FAD linked oxidase domain protein
AWU82_RS07925	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWU82_RS07930	COG3204	pilus organization
AWU82_RS07935	COG3204	pilus organization
AWU82_RS07940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWU82_RS07945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWU82_RS07960	COG0494	nUDIX hydrolase
AWU82_RS07965	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AWU82_RS07975	COG0730	response to heat
AWU82_RS07980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWU82_RS07985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AWU82_RS07990	COG0789	Transcriptional regulator
AWU82_RS08000	COG0583	DNA-binding transcription factor activity
AWU82_RS08005	COG3842	ATPase activity
AWU82_RS08010	COG1178	ABC-type Fe3 transport system permease component
AWU82_RS08015	COG1840	ABC-type Fe3 transport system, periplasmic component
AWU82_RS08035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWU82_RS08050	COG1823	symporter activity
AWU82_RS08060	COG0129	dihydroxy-acid dehydratase activity
AWU82_RS08065	COG2814	Major facilitator Superfamily
AWU82_RS08080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWU82_RS08085	COG0693	protein deglycase activity
AWU82_RS08095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWU82_RS08105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWU82_RS08110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWU82_RS08115	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AWU82_RS08145	COG0429	hydrolase of the alpha beta-hydrolase fold
AWU82_RS08150	COG0742	ribosomal rna small subunit methyltransferase
AWU82_RS08155	COG0612	Peptidase, M16
AWU82_RS08160	COG0612	Peptidase, M16
AWU82_RS08170	COG0552	protein localization to endoplasmic reticulum
AWU82_RS08175	COG2884	Cell division ATP-binding protein ftsE
AWU82_RS08180	COG2177	Part of the ABC transporter FtsEX involved in
AWU82_RS08190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWU82_RS08195	COG2363	Small membrane protein
AWU82_RS08205	COG2022	thiamine diphosphate biosynthetic process
AWU82_RS08210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWU82_RS08220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWU82_RS08225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWU82_RS08235	COG2813	Specifically methylates the guanine in position
AWU82_RS08235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWU82_RS08240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWU82_RS08245	COG1872	DUF167
AWU82_RS08270	COG0791	NLP P60 protein
AWU82_RS08280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWU82_RS08285	COG0540	Belongs to the ATCase OTCase family
AWU82_RS08290	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWU82_RS08295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWU82_RS08300	COG1678	Uncharacterized ACR, COG1678
AWU82_RS08310	COG0189	ligase activity
AWU82_RS08335	COG0643	Histidine kinase
AWU82_RS08335	COG0784	Response regulator, receiver
AWU82_RS08335	COG2198	Histidine kinase
AWU82_RS08350	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AWU82_RS08355	COG3052	prosthetic group binding
AWU82_RS08395	COG1272	protein, Hemolysin III
AWU82_RS08410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS08415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWU82_RS08430	COG2131	deaminase
AWU82_RS08435	COG3038	cytochrome b561
AWU82_RS08440	COG2353	YceI-like domain
AWU82_RS08445	COG0513	Belongs to the DEAD box helicase family
AWU82_RS08455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWU82_RS08460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AWU82_RS08470	COG2116	formate transmembrane transporter activity
AWU82_RS08480	COG2814	Major facilitator Superfamily
AWU82_RS08510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWU82_RS08515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWU82_RS08520	COG0640	Transcriptional regulator
AWU82_RS08530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWU82_RS08535	COG0126	phosphoglycerate kinase activity
AWU82_RS08595	COG1451	nucleotide metabolic process
AWU82_RS08605	COG2153	protein acetylation
AWU82_RS08615	COG1289	transmembrane transporter activity
AWU82_RS08620	COG2081	HI0933 family
AWU82_RS08625	COG0513	Belongs to the DEAD box helicase family
AWU82_RS08630	COG0477	Major facilitator Superfamily
AWU82_RS08635	COG0312	modulator of DNA gyrase
AWU82_RS08660	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AWU82_RS08665	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS08670	COG1309	transcriptional regulator
AWU82_RS08675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWU82_RS08680	COG4175	Glycine betaine
AWU82_RS08685	COG4176	ABC-type proline glycine betaine transport system permease component
AWU82_RS08695	COG1760	l-serine dehydratase
AWU82_RS08720	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWU82_RS08725	COG3246	L-lysine catabolic process to acetate
AWU82_RS08750	COG2304	oxidoreductase activity
AWU82_RS08770	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWU82_RS08770	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS08775	COG2181	nitrate reductase activity
AWU82_RS08775	COG0247	lactate metabolic process
AWU82_RS08780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AWU82_RS08795	COG1858	cytochrome C peroxidase
AWU82_RS08805	COG4638	Rieske (2fe-2S)
AWU82_RS08810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWU82_RS08810	COG1017	nitric oxide dioxygenase activity
AWU82_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS08855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWU82_RS08885	COG1063	alcohol dehydrogenase
AWU82_RS08900	COG0204	Acyl-transferase
AWU82_RS08905	COG0189	ligase activity
AWU82_RS08905	COG4067	protein conserved in archaea
AWU82_RS08910	COG0745	RESPONSE REGULATOR receiver
AWU82_RS08915	COG2205	protein histidine kinase activity
AWU82_RS08920	COG4452	Inner membrane protein CreD
AWU82_RS08940	COG4774	siderophore transport
AWU82_RS08945	COG3712	iron ion homeostasis
AWU82_RS08950	COG1595	DNA-templated transcription, initiation
AWU82_RS08955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWU82_RS08955	COG1199	ATP-dependent helicase activity
AWU82_RS08965	COG2204	response regulator
AWU82_RS08975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AWU82_RS08990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWU82_RS09000	COG3585	molybdate ion transport
AWU82_RS09000	COG2005	Transcriptional regulator
AWU82_RS09005	COG1040	competence protein
AWU82_RS09010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWU82_RS09015	COG0156	8-amino-7-oxononanoate synthase activity
AWU82_RS09020	COG2226	methyltransferase
AWU82_RS09020	COG1073	alpha beta
AWU82_RS09040	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS09045	COG1858	cytochrome C peroxidase
AWU82_RS09050	COG3706	GGDEF domain
AWU82_RS09055	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS09060	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS09065	COG0583	DNA-binding transcription factor activity
AWU82_RS09070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWU82_RS09080	COG0535	radical SAM domain protein
AWU82_RS09090	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AWU82_RS09095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWU82_RS09100	COG1025	Belongs to the peptidase M16 family
AWU82_RS09105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWU82_RS09135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWU82_RS09140	COG0358	DNA primase activity
AWU82_RS09150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWU82_RS09155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWU82_RS09160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWU82_RS09170	COG0617	tRNA 3'-terminal CCA addition
AWU82_RS09175	COG2719	SpoVR family
AWU82_RS09180	COG2718	Belongs to the UPF0229 family
AWU82_RS09185	COG2766	serine protein kinase
AWU82_RS09190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWU82_RS09195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWU82_RS09200	COG2967	ApaG domain
AWU82_RS09205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWU82_RS09210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AWU82_RS09215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWU82_RS09220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AWU82_RS09225	COG3178	'Phosphotransferase
AWU82_RS09230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWU82_RS09235	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AWU82_RS09250	COG2197	response regulator
AWU82_RS09255	COG3842	ATPase activity
AWU82_RS09265	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS09275	COG1454	alcohol dehydrogenase
AWU82_RS09280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWU82_RS09285	COG0546	phosphoglycolate phosphatase activity
AWU82_RS09300	COG0512	Glutamine amidotransferase of anthranilate synthase
AWU82_RS09305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWU82_RS09310	COG0134	indole-3-glycerol-phosphate synthase activity
AWU82_RS09325	COG1765	OsmC-like protein
AWU82_RS09330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWU82_RS09335	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AWU82_RS09340	COG0537	adenosine 5'-monophosphoramidase activity
AWU82_RS09345	COG4221	oxidoreductase activity
AWU82_RS09360	COG1981	membrane
AWU82_RS09365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWU82_RS09370	COG0316	Belongs to the HesB IscA family
AWU82_RS09375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWU82_RS09380	COG0739	heme binding
AWU82_RS09385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWU82_RS09405	COG3210	domain, Protein
AWU82_RS09410	COG0420	3'-5' exonuclease activity
AWU82_RS09440	COG2706	6-phosphogluconolactonase activity
AWU82_RS09450	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS09490	COG2267	carboxylic ester hydrolase activity
AWU82_RS09495	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS09505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWU82_RS09510	COG2186	Transcriptional regulator
AWU82_RS09525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWU82_RS09535	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS09545	COG3842	ATPase activity
AWU82_RS09550	COG0024	Methionine aminopeptidase
AWU82_RS09565	COG0626	cystathionine gamma-synthase activity
AWU82_RS09585	COG0784	Response regulator, receiver
AWU82_RS09585	COG2198	Histidine kinase
AWU82_RS09585	COG2205	protein histidine kinase activity
AWU82_RS09595	COG1773	rubredoxin
AWU82_RS09625	COG2207	Transcriptional regulator
AWU82_RS09630	COG0154	amidase activity
AWU82_RS09640	COG0861	Integral membrane protein TerC family
AWU82_RS09650	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWU82_RS09660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWU82_RS09700	COG2072	flavoprotein involved in K transport
AWU82_RS09725	COG1294	oxidase, subunit
AWU82_RS09730	COG1271	oxidase subunit
AWU82_RS09740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWU82_RS09745	COG3781	membrane
AWU82_RS09750	COG2205	protein histidine kinase activity
AWU82_RS09755	COG0745	RESPONSE REGULATOR receiver
AWU82_RS09765	COG0589	response to stress
AWU82_RS09780	COG0814	amino acid
AWU82_RS09795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWU82_RS09805	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS09815	COG2197	response regulator
AWU82_RS09835	COG1953	Uracil, thiamine, allantoin
AWU82_RS09855	COG1309	transcriptional regulator
AWU82_RS09860	COG0456	acetyltransferase
AWU82_RS09860	COG1214	PFAM Peptidase M22, glycoprotease
AWU82_RS09895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWU82_RS09905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AWU82_RS09920	COG0730	response to heat
AWU82_RS09930	COG0640	Transcriptional regulator
AWU82_RS09945	COG1522	sequence-specific DNA binding
AWU82_RS09950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWU82_RS09955	COG0022	dehydrogenase e1 component
AWU82_RS09965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWU82_RS09970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWU82_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS10000	COG1230	cation diffusion facilitator family transporter
AWU82_RS10035	COG1704	LemA family
AWU82_RS10040	COG0501	Belongs to the peptidase M48B family
AWU82_RS10045	COG0501	Belongs to the peptidase M48B family
AWU82_RS10060	COG0583	DNA-binding transcription factor activity
AWU82_RS10070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS10075	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWU82_RS10080	COG3383	formate dehydrogenase (NAD+) activity
AWU82_RS10100	COG5002	protein histidine kinase activity
AWU82_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS10120	COG0583	DNA-binding transcription factor activity
AWU82_RS10130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWU82_RS10135	COG2201	protein-glutamate methylesterase activity
AWU82_RS10140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWU82_RS10145	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWU82_RS10180	COG0534	Mate efflux family protein
AWU82_RS10200	COG3706	GGDEF domain
AWU82_RS10205	COG3474	cytochrome
AWU82_RS10210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWU82_RS10215	COG0697	spore germination
AWU82_RS10230	COG0659	secondary active sulfate transmembrane transporter activity
AWU82_RS10240	COG0456	acetyltransferase
AWU82_RS10255	COG1335	isochorismatase
AWU82_RS10270	COG0494	nUDIX hydrolase
AWU82_RS10275	COG3469	chitinase activity
AWU82_RS10325	COG2920	part of a sulfur-relay system
AWU82_RS10330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWU82_RS10335	COG0435	Glutathione S-transferase
AWU82_RS10340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWU82_RS10340	COG1648	precorrin-2 dehydrogenase activity
AWU82_RS10345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWU82_RS10350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWU82_RS10355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWU82_RS10360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AWU82_RS10365	COG1674	ftsk spoiiie
AWU82_RS10370	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AWU82_RS10375	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AWU82_RS10380	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AWU82_RS10385	COG0542	response to heat
AWU82_RS10390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWU82_RS10395	COG1278	Cold shock
AWU82_RS10415	COG0482	sulfurtransferase activity
AWU82_RS10420	COG2915	High frequency lysogenization protein hflD homolog
AWU82_RS10430	COG2850	peptidyl-arginine hydroxylation
AWU82_RS10435	COG2153	protein acetylation
AWU82_RS10445	COG2224	Isocitrate lyase
AWU82_RS10450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWU82_RS10455	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWU82_RS10460	COG0649	NAD binding
AWU82_RS10460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWU82_RS10475	COG1034	ATP synthesis coupled electron transport
AWU82_RS10480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AWU82_RS10485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWU82_RS10495	COG0713	ATP synthesis coupled electron transport
AWU82_RS10585	COG0395	ABC-type sugar transport system, permease component
AWU82_RS10595	COG3842	ATPase activity
AWU82_RS10600	COG3842	ATPase activity
AWU82_RS10605	COG3284	Transcriptional regulator
AWU82_RS10615	COG0215	cysteine-tRNA ligase activity
AWU82_RS10620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWU82_RS10630	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWU82_RS10635	COG2814	Major facilitator Superfamily
AWU82_RS10640	COG1566	PFAM secretion protein HlyD family protein
AWU82_RS10650	COG1846	Transcriptional regulator
AWU82_RS10655	COG2911	Protein conserved in bacteria
AWU82_RS10660	COG0729	surface antigen
AWU82_RS10670	COG0708	Exodeoxyribonuclease III
AWU82_RS10675	COG2885	chlorophyll binding
AWU82_RS10680	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS10690	COG0789	Transcriptional regulator
AWU82_RS10715	COG0318	PFAM AMP-dependent synthetase and ligase
AWU82_RS10720	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS10725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWU82_RS10730	COG1024	Enoyl-CoA hydratase
AWU82_RS10740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWU82_RS10750	COG2866	Carboxypeptidase
AWU82_RS10755	COG2814	Major facilitator Superfamily
AWU82_RS10760	COG3038	cytochrome b561
AWU82_RS10830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AWU82_RS10840	COG0217	transcriptional regulatory protein
AWU82_RS10855	COG2271	Major facilitator Superfamily
AWU82_RS10860	COG0583	DNA-binding transcription factor activity
AWU82_RS10865	COG0583	DNA-binding transcription factor activity
AWU82_RS10870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWU82_RS10875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWU82_RS10885	COG3038	cytochrome b561
AWU82_RS10895	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS10895	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWU82_RS10920	COG2814	Major facilitator Superfamily
AWU82_RS10925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWU82_RS10930	COG0776	regulation of translation
AWU82_RS10935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWU82_RS10940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWU82_RS10945	COG0740	serine-type endopeptidase activity
AWU82_RS10950	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWU82_RS10975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWU82_RS10980	COG1686	Belongs to the peptidase S11 family
AWU82_RS11000	COG1253	flavin adenine dinucleotide binding
AWU82_RS11010	COG0583	DNA-binding transcription factor activity
AWU82_RS11020	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AWU82_RS11030	COG3132	Protein of unknown function, DUF480
AWU82_RS11040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWU82_RS11060	COG0628	permease
AWU82_RS11065	COG0826	peptidase U32
AWU82_RS11070	COG0583	DNA-binding transcription factor activity
AWU82_RS11075	COG0697	spore germination
AWU82_RS11080	COG2186	Transcriptional regulator
AWU82_RS11120	COG0730	response to heat
AWU82_RS11135	COG0656	L-ascorbic acid biosynthetic process
AWU82_RS11145	COG0417	DNA replication proofreading
AWU82_RS11150	COG0517	IMP dehydrogenase activity
AWU82_RS11180	COG4166	transmembrane transport
AWU82_RS11185	COG4174	ABC transporter (Permease)
AWU82_RS11190	COG4239	(ABC) transporter, permease
AWU82_RS11195	COG4172	Belongs to the ABC transporter superfamily
AWU82_RS11230	COG0113	porphobilinogen synthase activity
AWU82_RS11235	COG0625	glutathione transferase activity
AWU82_RS11245	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AWU82_RS11265	COG1063	alcohol dehydrogenase
AWU82_RS11305	COG2056	Na+-H+ antiporter family
AWU82_RS11310	COG0840	transmembrane signaling receptor activity
AWU82_RS11340	COG0720	synthase
AWU82_RS11345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWU82_RS11350	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS11365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWU82_RS11370	COG2223	nitrite transmembrane transporter activity
AWU82_RS11375	COG4772	TonB-dependent receptor
AWU82_RS11385	COG1595	DNA-templated transcription, initiation
AWU82_RS11410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWU82_RS11415	COG1595	DNA-templated transcription, initiation
AWU82_RS11420	COG3712	iron ion homeostasis
AWU82_RS11435	COG3706	GGDEF domain
AWU82_RS11435	COG2203	Gaf domain
AWU82_RS11435	COG5001	Diguanylate cyclase
AWU82_RS11435	COG4251	negative regulation of phosphorylation
AWU82_RS11450	COG0583	DNA-binding transcription factor activity
AWU82_RS11480	COG2132	Multicopper oxidase
AWU82_RS11685	COG4695	Portal protein
AWU82_RS11745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWU82_RS11755	COG1968	undecaprenyl-diphosphatase activity
AWU82_RS11770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWU82_RS11775	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWU82_RS11790	COG1596	polysaccharide export
AWU82_RS11800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWU82_RS11860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWU82_RS11875	COG2853	Lipoprotein
AWU82_RS11890	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWU82_RS11890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWU82_RS11910	COG4591	ABC-type transport system involved in lipoprotein release permease component
AWU82_RS11915	COG1136	(ABC) transporter
AWU82_RS11920	COG4591	ABC-type transport system involved in lipoprotein release permease component
AWU82_RS11930	COG0584	glycerophosphoryl diester phosphodiesterase
AWU82_RS11935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWU82_RS11940	COG1477	protein flavinylation
AWU82_RS11955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWU82_RS11965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWU82_RS11970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWU82_RS12015	COG0183	Belongs to the thiolase family
AWU82_RS12020	COG1024	Enoyl-CoA hydratase
AWU82_RS12020	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWU82_RS12030	COG0589	response to stress
AWU82_RS12035	COG0488	(ABC) transporter
AWU82_RS12040	COG0741	lytic transglycosylase activity
AWU82_RS12045	COG1132	(ABC) transporter
AWU82_RS12055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWU82_RS12065	COG0425	Belongs to the sulfur carrier protein TusA family
AWU82_RS12070	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AWU82_RS12105	COG0477	Major facilitator Superfamily
AWU82_RS12110	COG0583	DNA-binding transcription factor activity
AWU82_RS12115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWU82_RS12120	COG0235	Class ii aldolase
AWU82_RS12125	COG0477	Major facilitator Superfamily
AWU82_RS12130	COG0583	DNA-binding transcription factor activity
AWU82_RS12135	COG0768	penicillin binding
AWU82_RS12200	COG0714	Associated with various cellular activities
AWU82_RS12245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWU82_RS12370	COG0673	inositol 2-dehydrogenase activity
AWU82_RS12375	COG2188	Transcriptional regulator
AWU82_RS12380	COG2081	HI0933 family
AWU82_RS12390	COG4521	taurine ABC transporter
AWU82_RS12395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWU82_RS12425	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS12435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWU82_RS12450	COG0587	DNA-directed DNA polymerase activity
AWU82_RS12455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWU82_RS12460	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS12465	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS12475	COG1177	transmembrane transport
AWU82_RS12480	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS12485	COG3842	ATPase activity
AWU82_RS12495	COG4191	Histidine kinase
AWU82_RS12495	COG0784	Response regulator, receiver
AWU82_RS12520	COG2172	sigma factor antagonist activity
AWU82_RS12525	COG1366	Belongs to the anti-sigma-factor antagonist family
AWU82_RS12530	COG1366	Belongs to the anti-sigma-factor antagonist family
AWU82_RS12560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWU82_RS12560	COG1024	Enoyl-CoA hydratase
AWU82_RS12565	COG1595	DNA-templated transcription, initiation
AWU82_RS12570	COG3712	iron ion homeostasis
AWU82_RS12575	COG4206	TonB-dependent receptor
AWU82_RS12595	COG4166	transmembrane transport
AWU82_RS12600	COG4174	ABC transporter (Permease)
AWU82_RS12605	COG4239	(ABC) transporter, permease
AWU82_RS12610	COG4172	Belongs to the ABC transporter superfamily
AWU82_RS12640	COG0616	signal peptide processing
AWU82_RS12655	COG1879	ABC-type sugar transport system periplasmic component
AWU82_RS12680	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AWU82_RS12685	COG0316	Belongs to the HesB IscA family
AWU82_RS12685	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWU82_RS12735	COG1253	flavin adenine dinucleotide binding
AWU82_RS12745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS12750	COG0765	amino acid transport
AWU82_RS12755	COG0765	amino acid transport
AWU82_RS12780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWU82_RS12785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWU82_RS12810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWU82_RS12815	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS12820	COG2610	gluconate transmembrane transporter activity
AWU82_RS12825	COG3290	protein histidine kinase activity
AWU82_RS12825	COG3829	transcription factor binding
AWU82_RS12830	COG4172	Belongs to the ABC transporter superfamily
AWU82_RS12835	COG4239	(ABC) transporter, permease
AWU82_RS12840	COG4174	ABC transporter (Permease)
AWU82_RS12845	COG4166	transmembrane transport
AWU82_RS12850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWU82_RS12855	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWU82_RS12865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AWU82_RS12875	COG2197	response regulator
AWU82_RS12880	COG0322	excinuclease ABC activity
AWU82_RS12920	COG0488	(ABC) transporter
AWU82_RS12930	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AWU82_RS12950	COG0604	alcohol dehydrogenase
AWU82_RS12955	COG2169	Transcriptional regulator
AWU82_RS12955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWU82_RS12960	COG3145	DNA-N1-methyladenine dioxygenase activity
AWU82_RS13020	COG3634	alkyl hydroperoxide reductase activity
AWU82_RS13040	COG2200	EAL domain
AWU82_RS13050	COG2962	Rard protein
AWU82_RS13055	COG0667	Aldo Keto reductase
AWU82_RS13060	COG0583	DNA-binding transcription factor activity
AWU82_RS13080	COG2271	Major facilitator Superfamily
AWU82_RS13085	COG3835	regulator
AWU82_RS13090	COG1929	Belongs to the glycerate kinase type-1 family
AWU82_RS13115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWU82_RS13125	COG1609	Transcriptional regulator
AWU82_RS13140	COG3468	outer membrane autotransporter barrel domain protein
AWU82_RS13160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS13165	COG0745	RESPONSE REGULATOR receiver
AWU82_RS13170	COG2205	protein histidine kinase activity
AWU82_RS13175	COG1335	isochorismatase
AWU82_RS13185	COG1595	DNA-templated transcription, initiation
AWU82_RS13200	COG1024	Enoyl-CoA hydratase
AWU82_RS13205	COG2816	NAD+ diphosphatase activity
AWU82_RS13215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWU82_RS13230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWU82_RS13235	COG2822	iron ion transport
AWU82_RS13245	COG2822	iron ion transport
AWU82_RS13250	COG0672	)-iron permease
AWU82_RS13255	COG2207	Transcriptional regulator
AWU82_RS13260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWU82_RS13270	COG0183	Belongs to the thiolase family
AWU82_RS13275	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS13280	COG1024	Enoyl-CoA hydratase
AWU82_RS13285	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS13290	COG1024	Enoyl-CoA hydratase
AWU82_RS13295	COG0657	acetylesterase activity
AWU82_RS13305	COG2124	cytochrome p450
AWU82_RS13320	COG2814	Major facilitator Superfamily
AWU82_RS13350	COG0765	amino acid transport
AWU82_RS13355	COG0165	Argininosuccinate lyase
AWU82_RS13380	COG2076	Multidrug Resistance protein
AWU82_RS13385	COG2076	Multidrug Resistance protein
AWU82_RS13390	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWU82_RS13395	COG0726	polysaccharide deacetylase
AWU82_RS13400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWU82_RS13400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWU82_RS13405	COG0463	Glycosyl transferase, family 2
AWU82_RS13410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWU82_RS13415	COG4974	Belongs to the 'phage' integrase family
AWU82_RS13425	COG3008	intermembrane lipid transfer
AWU82_RS13430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS13440	COG0174	glutamine synthetase
AWU82_RS13450	COG1595	DNA-templated transcription, initiation
AWU82_RS13455	COG3712	iron ion homeostasis
AWU82_RS13460	COG4774	siderophore transport
AWU82_RS13465	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AWU82_RS13470	COG4191	Histidine kinase
AWU82_RS13470	COG0784	Response regulator, receiver
AWU82_RS13475	COG3046	protein related to deoxyribodipyrimidine photolyase
AWU82_RS13490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS13495	COG0765	amino acid transport
AWU82_RS13525	COG3781	membrane
AWU82_RS13545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWU82_RS13565	COG2233	PERMEase
AWU82_RS13570	COG0583	DNA-binding transcription factor activity
AWU82_RS13580	COG0477	Major facilitator Superfamily
AWU82_RS13600	COG0583	DNA-binding transcription factor activity
AWU82_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS13610	COG2271	Major facilitator Superfamily
AWU82_RS13615	COG3959	Transketolase, thiamine diphosphate binding domain
AWU82_RS13620	COG3958	Transketolase
AWU82_RS13625	COG4977	sequence-specific DNA binding
AWU82_RS13630	COG0300	oxidoreductase activity
AWU82_RS13645	COG1944	ATP diphosphatase activity
AWU82_RS13660	COG3276	selenocysteine insertion sequence binding
AWU82_RS13665	COG1921	L-seryl-tRNASec selenium transferase activity
AWU82_RS13690	COG3058	Necessary for formate dehydrogenase activity
AWU82_RS13695	COG2864	formate dehydrogenase
AWU82_RS13700	COG0437	4 iron, 4 sulfur cluster binding
AWU82_RS13705	COG0243	molybdopterin cofactor binding
AWU82_RS13705	COG3383	formate dehydrogenase (NAD+) activity
AWU82_RS13710	COG0243	molybdopterin cofactor binding
AWU82_RS13710	COG3383	formate dehydrogenase (NAD+) activity
AWU82_RS13715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AWU82_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS13745	COG1199	ATP-dependent helicase activity
AWU82_RS13765	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWU82_RS13770	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWU82_RS13820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS13835	COG0210	DNA helicase
AWU82_RS13850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWU82_RS13860	COG0604	alcohol dehydrogenase
AWU82_RS13860	COG3321	synthase
AWU82_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS13875	COG2207	Transcriptional regulator
AWU82_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS13890	COG0583	DNA-binding transcription factor activity
AWU82_RS13900	COG1566	PFAM secretion protein HlyD family protein
AWU82_RS13910	COG2207	Transcriptional regulator
AWU82_RS13930	COG1566	PFAM secretion protein HlyD family protein
AWU82_RS13950	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AWU82_RS13965	COG5002	protein histidine kinase activity
AWU82_RS13965	COG2205	protein histidine kinase activity
AWU82_RS13965	COG0784	Response regulator, receiver
AWU82_RS13975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWU82_RS13980	COG2205	protein histidine kinase activity
AWU82_RS13980	COG2198	Histidine kinase
AWU82_RS13980	COG0784	Response regulator, receiver
AWU82_RS14015	COG1175	transmembrane transport
AWU82_RS14030	COG0246	Mannitol dehydrogenase
AWU82_RS14035	COG1070	Carbohydrate kinase
AWU82_RS14040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWU82_RS14100	COG4574	serine-type endopeptidase inhibitor activity
AWU82_RS14110	COG0598	Magnesium transport protein CorA
AWU82_RS14125	COG2133	pyrroloquinoline quinone binding
AWU82_RS14135	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AWU82_RS14145	COG0488	(ABC) transporter
AWU82_RS14160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWU82_RS14180	COG1968	undecaprenyl-diphosphatase activity
AWU82_RS14185	COG0840	transmembrane signaling receptor activity
AWU82_RS14230	COG2204	response regulator
AWU82_RS14245	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWU82_RS14250	COG0561	phosphatase activity
AWU82_RS14255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWU82_RS14260	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AWU82_RS14270	COG2194	sulfuric ester hydrolase activity
AWU82_RS14290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AWU82_RS14305	COG0010	Belongs to the arginase family
AWU82_RS14320	COG2233	PERMEase
AWU82_RS14370	COG2366	antibiotic biosynthetic process
AWU82_RS14425	COG1238	metal cluster binding
AWU82_RS14430	COG0596	Alpha beta hydrolase
AWU82_RS14435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWU82_RS14440	COG0297	glycogen (starch) synthase activity
AWU82_RS14445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWU82_RS14495	COG3568	Endonuclease Exonuclease Phosphatase
AWU82_RS14505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWU82_RS14520	COG1285	pathogenesis
AWU82_RS14530	COG0348	domain, Protein
AWU82_RS14535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWU82_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS14575	COG3795	YCII-related domain
AWU82_RS14605	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWU82_RS14610	COG3278	Belongs to the heme-copper respiratory oxidase family
AWU82_RS14635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWU82_RS14665	COG0811	peptide transport
AWU82_RS14705	COG0697	spore germination
AWU82_RS14710	COG1522	sequence-specific DNA binding
AWU82_RS14730	COG3642	lipopolysaccharide core region biosynthetic process
AWU82_RS14765	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS14770	COG4221	oxidoreductase activity
AWU82_RS14775	COG2267	carboxylic ester hydrolase activity
AWU82_RS14780	COG3321	synthase
AWU82_RS14780	COG0604	alcohol dehydrogenase
AWU82_RS14790	COG2207	Transcriptional regulator
AWU82_RS14810	COG4221	oxidoreductase activity
AWU82_RS14820	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS14835	COG2207	Transcriptional regulator
AWU82_RS14840	COG1764	response to oxidative stress
AWU82_RS14860	COG4566	intracellular signal transduction
AWU82_RS14865	COG4191	Histidine kinase
AWU82_RS14880	COG4566	intracellular signal transduction
AWU82_RS14885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWU82_RS14895	COG4566	intracellular signal transduction
AWU82_RS14905	COG0583	DNA-binding transcription factor activity
AWU82_RS14910	COG2814	Major facilitator Superfamily
AWU82_RS14915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AWU82_RS14915	COG2010	Cytochrome c
AWU82_RS14920	COG2080	2 iron, 2 sulfur cluster binding
AWU82_RS14925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AWU82_RS14925	COG2010	Cytochrome c
AWU82_RS14930	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS14950	COG2995	paraquat-inducible protein a
AWU82_RS14955	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS14965	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWU82_RS14970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AWU82_RS14975	COG3639	organic phosphonate transmembrane transporter activity
AWU82_RS14980	COG3639	organic phosphonate transmembrane transporter activity
AWU82_RS15020	COG0625	glutathione transferase activity
AWU82_RS15075	COG0456	acetyltransferase
AWU82_RS15075	COG1846	Transcriptional regulator
AWU82_RS15110	COG1595	DNA-templated transcription, initiation
AWU82_RS15115	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWU82_RS15130	COG0640	Transcriptional regulator
AWU82_RS15140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWU82_RS15145	COG0431	NADPH-dependent FMN reductase
AWU82_RS15150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWU82_RS15170	COG1511	domain protein
AWU82_RS15170	COG3264	Mechanosensitive ion channel
AWU82_RS15175	COG2384	SAM-dependent methyltransferase
AWU82_RS15195	COG0596	Alpha beta hydrolase
AWU82_RS15210	COG0826	peptidase U32
AWU82_RS15250	COG0477	Major facilitator Superfamily
AWU82_RS15265	COG0251	oxidation-reduction process
AWU82_RS15270	COG2957	Belongs to the agmatine deiminase family
AWU82_RS15285	COG2957	Belongs to the agmatine deiminase family
AWU82_RS15290	COG0583	DNA-binding transcription factor activity
AWU82_RS15305	COG0251	oxidation-reduction process
AWU82_RS15310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWU82_RS15315	COG0066	3-isopropylmalate dehydratase activity
AWU82_RS15320	COG0583	DNA-binding transcription factor activity
AWU82_RS15340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWU82_RS15370	COG1064	alcohol dehydrogenase
AWU82_RS15390	COG0531	amino acid
AWU82_RS15400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWU82_RS15410	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWU82_RS15415	COG1129	ABC transporter
AWU82_RS15420	COG2011	ABC-type metal ion transport system permease component
AWU82_RS15425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWU82_RS15465	COG3485	protocatechuate 3,4-dioxygenase
AWU82_RS15470	COG4829	muconolactone delta-isomerase
AWU82_RS15475	COG4948	Mandelate Racemase Muconate Lactonizing
AWU82_RS15520	COG0531	amino acid
AWU82_RS15525	COG3938	Belongs to the proline racemase family
AWU82_RS15530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWU82_RS15545	COG2207	Transcriptional regulator
AWU82_RS15545	COG1609	Transcriptional regulator
AWU82_RS15550	COG2115	Belongs to the xylose isomerase family
AWU82_RS15555	COG4213	ABC transporter substrate-binding protein
AWU82_RS15560	COG1129	ABC transporter
AWU82_RS15565	COG4214	carbohydrate transport
AWU82_RS15585	COG0604	alcohol dehydrogenase
AWU82_RS15585	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS15585	COG3321	synthase
AWU82_RS15590	COG1335	isochorismatase
AWU82_RS15595	COG5001	Diguanylate cyclase
AWU82_RS15595	COG2203	Gaf domain
AWU82_RS15595	COG4251	negative regulation of phosphorylation
AWU82_RS15595	COG3706	GGDEF domain
AWU82_RS15600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWU82_RS15615	COG0583	DNA-binding transcription factor activity
AWU82_RS15620	COG0156	8-amino-7-oxononanoate synthase activity
AWU82_RS15630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWU82_RS15635	COG2259	Doxx family
AWU82_RS15640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWU82_RS15645	COG0163	prenyltransferase activity
AWU82_RS15655	COG0583	DNA-binding transcription factor activity
AWU82_RS15710	COG1473	amidohydrolase
AWU82_RS15735	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AWU82_RS15740	COG4566	intracellular signal transduction
AWU82_RS15785	COG2175	clavaminate synthase activity
AWU82_RS15790	COG3251	PFAM MbtH domain protein
AWU82_RS15820	COG1764	response to oxidative stress
AWU82_RS15825	COG0753	catalase activity
AWU82_RS15860	COG0596	Alpha beta hydrolase
AWU82_RS15865	COG0596	Alpha beta hydrolase
AWU82_RS15875	COG3321	synthase
AWU82_RS15875	COG0604	alcohol dehydrogenase
AWU82_RS15875	COG4221	oxidoreductase activity
AWU82_RS15875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWU82_RS15880	COG4191	Histidine kinase
AWU82_RS15890	COG4566	intracellular signal transduction
AWU82_RS15910	COG1132	(ABC) transporter
AWU82_RS15920	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS15925	COG1301	dicarboxylic acid transport
AWU82_RS15935	COG0583	DNA-binding transcription factor activity
AWU82_RS15945	COG0300	oxidoreductase activity
AWU82_RS15950	COG2207	Transcriptional regulator
AWU82_RS15955	COG2169	Transcriptional regulator
AWU82_RS15960	COG2271	Major facilitator Superfamily
AWU82_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS15975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWU82_RS15985	COG1309	transcriptional regulator
AWU82_RS15995	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS16000	COG2203	Gaf domain
AWU82_RS16000	COG5001	Diguanylate cyclase
AWU82_RS16000	COG3706	GGDEF domain
AWU82_RS16000	COG4251	negative regulation of phosphorylation
AWU82_RS16005	COG0500	methyltransferase
AWU82_RS16020	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AWU82_RS16025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWU82_RS16030	COG1183	phosphatidylcholine synthase activity
AWU82_RS16035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWU82_RS16045	COG0028	Belongs to the TPP enzyme family
AWU82_RS16065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWU82_RS16095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AWU82_RS16100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWU82_RS16105	COG4558	Periplasmic binding protein
AWU82_RS16115	COG1489	DNA binding
AWU82_RS16120	COG0436	Aminotransferase
AWU82_RS16125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWU82_RS16130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWU82_RS16135	COG4191	Histidine kinase
AWU82_RS16155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWU82_RS16160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWU82_RS16165	COG0166	Belongs to the GPI family
AWU82_RS16170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWU82_RS16175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWU82_RS16190	COG2823	Periplasmic or secreted lipoprotein
AWU82_RS16210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWU82_RS16215	COG0237	dephospho-CoA kinase activity
AWU82_RS16220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AWU82_RS16255	COG1252	NADH dehydrogenase
AWU82_RS16315	COG0542	response to heat
AWU82_RS16350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS16380	COG4969	Belongs to the N-Me-Phe pilin family
AWU82_RS16390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWU82_RS16395	COG1047	Peptidyl-prolyl cis-trans
AWU82_RS16400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWU82_RS16405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWU82_RS16410	COG0196	riboflavin kinase activity
AWU82_RS16420	COG0268	Binds directly to 16S ribosomal RNA
AWU82_RS16425	COG3045	CreA protein
AWU82_RS16430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWU82_RS16435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWU82_RS16440	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWU82_RS16445	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWU82_RS16450	COG0142	geranyltranstransferase activity
AWU82_RS16455	COG2824	Alkylphosphonate utilization operon protein PhnA
AWU82_RS16460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWU82_RS16465	COG0545	Peptidyl-prolyl cis-trans isomerase
AWU82_RS16475	COG2862	Uncharacterized protein family, UPF0114
AWU82_RS16490	COG1067	ATP-dependent peptidase activity
AWU82_RS16510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWU82_RS16520	COG0488	(ABC) transporter
AWU82_RS16530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWU82_RS16550	COG0523	cobalamin synthesis protein
AWU82_RS16555	COG2879	small protein
AWU82_RS16560	COG1966	Carbon starvation protein
AWU82_RS16580	COG1970	mechanosensitive ion channel activity
AWU82_RS16590	COG2197	response regulator
AWU82_RS16595	COG2813	Specifically methylates the guanine in position
AWU82_RS16600	COG1294	oxidase, subunit
AWU82_RS16605	COG1271	oxidase subunit
AWU82_RS16625	COG2252	PERMEase
AWU82_RS16630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWU82_RS16645	COG0583	DNA-binding transcription factor activity
AWU82_RS16650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWU82_RS16655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWU82_RS16660	COG1309	transcriptional regulator
AWU82_RS16665	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AWU82_RS16665	COG1082	Xylose isomerase domain protein TIM barrel
AWU82_RS16670	COG0477	Major facilitator Superfamily
AWU82_RS16690	COG1053	succinate dehydrogenase
AWU82_RS16695	COG0656	L-ascorbic acid biosynthetic process
AWU82_RS16700	COG2321	neutral zinc metallopeptidase
AWU82_RS16715	COG1946	Acyl-CoA thioesterase
AWU82_RS16725	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWU82_RS16735	COG0513	Belongs to the DEAD box helicase family
AWU82_RS16740	COG0697	spore germination
AWU82_RS16745	COG1522	sequence-specific DNA binding
AWU82_RS16750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWU82_RS16750	COG1199	ATP-dependent helicase activity
AWU82_RS16760	COG3416	Protein conserved in bacteria
AWU82_RS16795	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS16800	COG0583	DNA-binding transcription factor activity
AWU82_RS16805	COG1643	Atp-dependent helicase
AWU82_RS16815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWU82_RS16825	COG1522	sequence-specific DNA binding
AWU82_RS16840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWU82_RS16845	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS16850	COG2198	Histidine kinase
AWU82_RS16850	COG0784	Response regulator, receiver
AWU82_RS16850	COG2205	protein histidine kinase activity
AWU82_RS16860	COG0352	thiamine-phosphate diphosphorylase activity
AWU82_RS16865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWU82_RS16880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWU82_RS16885	COG1702	phosphate starvation-inducible protein PhoH
AWU82_RS16890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWU82_RS16895	COG4535	Mg2 and Co2 transporter CorC
AWU82_RS16900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AWU82_RS16915	COG0495	leucyl-tRNA aminoacylation
AWU82_RS16935	COG2951	lytic endotransglycosylase activity
AWU82_RS16940	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWU82_RS16945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWU82_RS16950	COG0321	lipoyl(octanoyl) transferase activity
AWU82_RS16955	COG2921	Belongs to the UPF0250 family
AWU82_RS16960	COG1686	Belongs to the peptidase S11 family
AWU82_RS16970	COG2951	lytic endotransglycosylase activity
AWU82_RS16975	COG0772	Belongs to the SEDS family
AWU82_RS16980	COG0768	penicillin binding
AWU82_RS16985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AWU82_RS16995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWU82_RS17000	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWU82_RS17005	COG2094	Belongs to the DNA glycosylase MPG family
AWU82_RS17010	COG0586	Pfam SNARE associated Golgi protein
AWU82_RS17030	COG1346	cytolysis
AWU82_RS17050	COG0702	epimerase
AWU82_RS17065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWU82_RS17070	COG3284	Transcriptional regulator
AWU82_RS17085	COG4303	Ethanolamine ammonia lyase large subunit
AWU82_RS17090	COG4302	ethanolamine ammonia-lyase activity
AWU82_RS17095	COG0456	acetyltransferase
AWU82_RS17100	COG0586	Pfam SNARE associated Golgi protein
AWU82_RS17105	COG3228	Belongs to the MtfA family
AWU82_RS17110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWU82_RS17125	COG4676	Protein conserved in bacteria
AWU82_RS17130	COG5445	Predicted secreted protein (DUF2300)
AWU82_RS17145	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
AWU82_RS17150	COG4676	Protein conserved in bacteria
AWU82_RS17160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWU82_RS17175	COG1722	exodeoxyribonuclease VII activity
AWU82_RS17180	COG0142	geranyltranstransferase activity
AWU82_RS17185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWU82_RS17190	COG4206	TonB-dependent receptor
AWU82_RS17195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWU82_RS17205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWU82_RS17215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWU82_RS17220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWU82_RS17225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWU82_RS17230	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWU82_RS17245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWU82_RS17245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWU82_RS17250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWU82_RS17260	COG2264	protein methyltransferase activity
AWU82_RS17265	COG3118	belongs to the thioredoxin family
AWU82_RS17315	COG3047	cAMP biosynthetic process
AWU82_RS17320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWU82_RS17330	COG1201	RNA secondary structure unwinding
AWU82_RS17335	COG0668	transmembrane transport
AWU82_RS17340	COG2814	Major facilitator Superfamily
AWU82_RS17350	COG3568	Endonuclease Exonuclease Phosphatase
AWU82_RS17355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWU82_RS17360	COG0392	lysyltransferase activity
AWU82_RS17375	COG4753	response regulator
AWU82_RS17375	COG2207	Transcriptional regulator
AWU82_RS17380	COG1335	isochorismatase
AWU82_RS17385	COG3789	protein conserved in bacteria
AWU82_RS17390	COG1842	Phage shock protein A
AWU82_RS17400	COG3766	membrane
AWU82_RS17410	COG0754	glutathionylspermidine amidase activity
AWU82_RS17415	COG0629	single-stranded DNA binding
AWU82_RS17420	COG2814	Major facilitator Superfamily
AWU82_RS17425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWU82_RS17430	COG2193	ferroxidase activity
AWU82_RS17440	COG0203	ribosomal protein L17
AWU82_RS17445	COG0202	RNA polymerase activity
AWU82_RS17450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWU82_RS17455	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWU82_RS17460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWU82_RS17470	COG0200	Binds to the 23S rRNA
AWU82_RS17475	COG1841	ribosomal large subunit assembly
AWU82_RS17480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWU82_RS17485	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWU82_RS17490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWU82_RS17495	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWU82_RS17500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWU82_RS17505	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWU82_RS17510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWU82_RS17515	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWU82_RS17520	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWU82_RS17525	COG0255	Belongs to the universal ribosomal protein uL29 family
AWU82_RS17530	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWU82_RS17535	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWU82_RS17540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWU82_RS17545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWU82_RS17550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWU82_RS17555	COG0089	rRNA binding
AWU82_RS17560	COG0088	Forms part of the polypeptide exit tunnel
AWU82_RS17565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWU82_RS17570	COG0051	transcription antitermination factor activity, RNA binding
AWU82_RS17575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWU82_RS17580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWU82_RS17585	COG0049	tRNA binding
AWU82_RS17590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWU82_RS17595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWU82_RS17600	COG0085	RNA polymerase activity
AWU82_RS17605	COG0222	ribosome binding
AWU82_RS17610	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWU82_RS17615	COG0081	regulation of translation
AWU82_RS17620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWU82_RS17640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWU82_RS17665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWU82_RS17700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWU82_RS17710	COG0625	glutathione transferase activity
AWU82_RS17730	COG0277	FAD linked oxidase domain protein
AWU82_RS17735	COG0277	FAD linked oxidase domain protein
AWU82_RS17740	COG0247	lactate metabolic process
AWU82_RS17745	COG3300	MHYT domain
AWU82_RS17745	COG5001	Diguanylate cyclase
AWU82_RS17755	COG0577	efflux transmembrane transporter activity
AWU82_RS17755	COG1136	(ABC) transporter
AWU82_RS17760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS17790	COG1999	signal sequence binding
AWU82_RS17815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AWU82_RS17820	COG0308	aminopeptidase N
AWU82_RS17830	COG3139	Protein of unknown function (DUF1315)
AWU82_RS17835	COG0705	Rhomboid family
AWU82_RS17840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWU82_RS17845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWU82_RS17855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWU82_RS17860	COG0431	NADPH-dependent FMN reductase
AWU82_RS17885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWU82_RS17890	COG0328	RNA-DNA hybrid ribonuclease activity
AWU82_RS17900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWU82_RS17905	COG1388	LysM domain
AWU82_RS17905	COG0741	lytic transglycosylase activity
AWU82_RS17910	COG4166	transmembrane transport
AWU82_RS17915	COG4166	transmembrane transport
AWU82_RS17920	COG4174	ABC transporter (Permease)
AWU82_RS17925	COG4239	(ABC) transporter, permease
AWU82_RS17930	COG4172	Belongs to the ABC transporter superfamily
AWU82_RS17945	COG0583	DNA-binding transcription factor activity
AWU82_RS17950	COG2199	diguanylate cyclase activity
AWU82_RS17950	COG2203	Gaf domain
AWU82_RS17980	COG3706	GGDEF domain
AWU82_RS18030	COG4251	negative regulation of phosphorylation
AWU82_RS18050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWU82_RS18050	COG2169	Transcriptional regulator
AWU82_RS18060	COG3791	Glutathione-dependent formaldehyde-activating
AWU82_RS18070	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWU82_RS18075	COG0583	DNA-binding transcription factor activity
AWU82_RS18080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWU82_RS18090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWU82_RS18105	COG0174	glutamine synthetase
AWU82_RS18110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS18130	COG1566	PFAM secretion protein HlyD family protein
AWU82_RS18155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWU82_RS18190	COG1917	Cupin 2, conserved barrel domain protein
AWU82_RS18190	COG1396	sequence-specific DNA binding
AWU82_RS18195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS18200	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS18205	COG0174	glutamine synthetase
AWU82_RS18210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AWU82_RS18215	COG3842	ATPase activity
AWU82_RS18220	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS18225	COG1177	transmembrane transport
AWU82_RS18235	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWU82_RS18245	COG5507	3-demethylubiquinone-9 3-methyltransferase
AWU82_RS18265	COG1620	l-lactate permease
AWU82_RS18270	COG2080	2 iron, 2 sulfur cluster binding
AWU82_RS18275	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AWU82_RS18280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AWU82_RS18310	COG0579	oxidoreductase
AWU82_RS18410	COG3220	belongs to the UPF0276 family
AWU82_RS18415	COG4106	trans-aconitate 2-methyltransferase activity
AWU82_RS18420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWU82_RS18425	COG0583	DNA-binding transcription factor activity
AWU82_RS18430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWU82_RS18445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWU82_RS18450	COG0583	DNA-binding transcription factor activity
AWU82_RS18515	COG1335	isochorismatase
AWU82_RS18520	COG0174	glutamine synthetase
AWU82_RS18530	COG0531	amino acid
AWU82_RS18560	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AWU82_RS18570	COG3706	GGDEF domain
AWU82_RS18575	COG2072	flavoprotein involved in K transport
AWU82_RS18580	COG2267	carboxylic ester hydrolase activity
AWU82_RS18585	COG5383	Protein conserved in bacteria
AWU82_RS18625	COG0583	DNA-binding transcription factor activity
AWU82_RS18635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AWU82_RS18640	COG3842	ATPase activity
AWU82_RS18645	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWU82_RS18650	COG1177	transmembrane transport
AWU82_RS18655	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS18680	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AWU82_RS18690	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS18705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AWU82_RS18725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS18725	COG2205	protein histidine kinase activity
AWU82_RS18745	COG4974	Belongs to the 'phage' integrase family
AWU82_RS18755	COG1607	acyl-coa hydrolase
AWU82_RS18760	COG0335	large ribosomal subunit rRNA binding
AWU82_RS18765	COG0336	Belongs to the RNA methyltransferase TrmD family
AWU82_RS18770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWU82_RS18775	COG0228	four-way junction DNA binding
AWU82_RS18780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWU82_RS18790	COG4536	flavin adenine dinucleotide binding
AWU82_RS18795	COG0477	Major facilitator Superfamily
AWU82_RS18800	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AWU82_RS18820	COG0494	nUDIX hydrolase
AWU82_RS18835	COG2188	Transcriptional regulator
AWU82_RS18840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWU82_RS18845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWU82_RS18850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWU82_RS18850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWU82_RS18855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWU82_RS18855	COG1263	PTS System
AWU82_RS18855	COG2190	(PTS) system
AWU82_RS18870	COG0047	phosphoribosylformylglycinamidine synthase activity
AWU82_RS18870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWU82_RS18875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AWU82_RS18880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AWU82_RS18885	COG1381	Involved in DNA repair and RecF pathway recombination
AWU82_RS18890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWU82_RS18895	COG0571	ribonuclease III activity
AWU82_RS18900	COG0681	Belongs to the peptidase S26 family
AWU82_RS18905	COG0481	GTPase activity
AWU82_RS18910	COG0795	lipopolysaccharide-transporting ATPase activity
AWU82_RS18915	COG0795	lipopolysaccharide-transporting ATPase activity
AWU82_RS18920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWU82_RS18935	COG0525	valine-tRNA ligase activity
AWU82_RS18940	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AWU82_RS18950	COG3081	Nucleoid-associated protein
AWU82_RS18965	COG2827	Endonuclease containing a URI domain
AWU82_RS18975	COG2807	transmembrane transport
AWU82_RS18980	COG2186	Transcriptional regulator
AWU82_RS18995	COG1126	abc transporter atp-binding protein
AWU82_RS19000	COG0765	amino acid transport
AWU82_RS19005	COG4597	amino acid ABC transporter
AWU82_RS19010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS19015	COG0400	carboxylic ester hydrolase activity
AWU82_RS19020	COG0513	Belongs to the DEAD box helicase family
AWU82_RS19050	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWU82_RS19055	COG0315	cyclic pyranopterin monophosphate synthase activity
AWU82_RS19060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWU82_RS19070	COG3022	response to hydroperoxide
AWU82_RS19080	COG1215	transferase activity, transferring glycosyl groups
AWU82_RS19085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS19090	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AWU82_RS19100	COG3420	alginic acid biosynthetic process
AWU82_RS19115	COG1696	Membrane protein involved in D-alanine export
AWU82_RS19130	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AWU82_RS19130	COG0662	Cupin 2, conserved barrel domain protein
AWU82_RS19150	COG0300	oxidoreductase activity
AWU82_RS19155	COG1566	PFAM secretion protein HlyD family protein
AWU82_RS19175	COG0583	DNA-binding transcription factor activity
AWU82_RS19185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWU82_RS19205	COG4774	siderophore transport
AWU82_RS19235	COG1595	DNA-templated transcription, initiation
AWU82_RS19240	COG3712	iron ion homeostasis
AWU82_RS19245	COG4772	TonB-dependent receptor
AWU82_RS19255	COG0583	DNA-binding transcription factor activity
AWU82_RS19260	COG1760	l-serine dehydratase
AWU82_RS19265	COG0814	amino acid
AWU82_RS19285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWU82_RS19305	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWU82_RS19310	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AWU82_RS19345	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS19360	COG1346	cytolysis
AWU82_RS19365	COG1380	Effector of murein hydrolase LrgA
AWU82_RS19370	COG0583	DNA-binding transcription factor activity
AWU82_RS19380	COG1366	Belongs to the anti-sigma-factor antagonist family
AWU82_RS19405	COG0302	gtp cyclohydrolase
AWU82_RS19410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWU82_RS19425	COG0492	ferredoxin-NADP+ reductase activity
AWU82_RS19430	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AWU82_RS19435	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS19445	COG0386	Belongs to the glutathione peroxidase family
AWU82_RS19450	COG1047	Peptidyl-prolyl cis-trans
AWU82_RS19460	COG0280	phosphate acetyltransferase
AWU82_RS19460	COG0857	belongs to the CobB CobQ family
AWU82_RS19465	COG0204	Acyl-transferase
AWU82_RS19475	COG0175	sulfate reduction
AWU82_RS19485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWU82_RS19500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWU82_RS19505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWU82_RS19510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWU82_RS19515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWU82_RS19520	COG5007	Belongs to the BolA IbaG family
AWU82_RS19535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AWU82_RS19540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWU82_RS19545	COG1127	ABC transporter
AWU82_RS19555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AWU82_RS19565	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AWU82_RS19570	COG1137	ATPase activity
AWU82_RS19575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AWU82_RS19580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWU82_RS19590	COG1660	Displays ATPase and GTPase activities
AWU82_RS19595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWU82_RS19625	COG0312	modulator of DNA gyrase
AWU82_RS19630	COG3028	Belongs to the UPF0307 family
AWU82_RS19635	COG0312	modulator of DNA gyrase
AWU82_RS19640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWU82_RS19650	COG1530	ribonuclease E activity
AWU82_RS19655	COG0424	maF-like protein
AWU82_RS19660	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AWU82_RS19665	COG1792	Involved in formation and maintenance of cell shape
AWU82_RS19670	COG1077	Cell shape determining protein MreB Mrl
AWU82_RS19675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWU82_RS19680	COG0154	amidase activity
AWU82_RS19685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWU82_RS19690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWU82_RS19700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWU82_RS19710	COG2721	sulfolactate sulfo-lyase activity
AWU82_RS19715	COG2271	Major facilitator Superfamily
AWU82_RS19725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWU82_RS19750	COG4178	(ABC) transporter
AWU82_RS19755	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AWU82_RS19775	COG0747	negative chemotaxis
AWU82_RS19780	COG0747	negative chemotaxis
AWU82_RS19785	COG0747	negative chemotaxis
AWU82_RS19795	COG0747	negative chemotaxis
AWU82_RS19800	COG0601	transmembrane transport
AWU82_RS19805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWU82_RS19810	COG0444	Belongs to the ABC transporter superfamily
AWU82_RS19815	COG4608	Belongs to the ABC transporter superfamily
AWU82_RS19825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AWU82_RS19850	COG0019	diaminopimelate decarboxylase activity
AWU82_RS19870	COG3128	pkhd-type hydroxylase
AWU82_RS19880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWU82_RS19890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWU82_RS19890	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AWU82_RS19890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWU82_RS19895	COG1105	Belongs to the carbohydrate kinase PfkB family
AWU82_RS19900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWU82_RS19900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWU82_RS19905	COG1609	Transcriptional regulator
AWU82_RS19910	COG0084	hydrolase, TatD family'
AWU82_RS19920	COG0840	transmembrane signaling receptor activity
AWU82_RS19955	COG1185	polyribonucleotide nucleotidyltransferase activity
AWU82_RS19960	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWU82_RS19965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWU82_RS19970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWU82_RS19975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWU82_RS19980	COG0195	Participates in both transcription termination and antitermination
AWU82_RS19985	COG0779	Required for maturation of 30S ribosomal subunits
AWU82_RS20000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWU82_RS20005	COG0149	triose-phosphate isomerase activity
AWU82_RS20010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWU82_RS20015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWU82_RS20025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AWU82_RS20040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWU82_RS20045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWU82_RS20050	COG0505	Belongs to the CarA family
AWU82_RS20055	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWU82_RS20060	COG0484	heat shock protein binding
AWU82_RS20065	COG0443	Heat shock 70 kDa protein
AWU82_RS20070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWU82_RS20075	COG0497	DNA recombination
AWU82_RS20080	COG0735	belongs to the Fur family
AWU82_RS20085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWU82_RS20090	COG2914	Belongs to the UPF0125 (RnfH) family
AWU82_RS20100	COG0733	neurotransmitter:sodium symporter activity
AWU82_RS20105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWU82_RS20115	COG1620	l-lactate permease
AWU82_RS20120	COG0247	lactate metabolic process
AWU82_RS20170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWU82_RS20185	COG0840	transmembrane signaling receptor activity
AWU82_RS20205	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AWU82_RS20215	COG2610	gluconate transmembrane transporter activity
AWU82_RS20225	COG0583	DNA-binding transcription factor activity
AWU82_RS20230	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWU82_RS20250	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWU82_RS20280	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS20295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWU82_RS20305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWU82_RS20310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWU82_RS20335	COG2885	chlorophyll binding
AWU82_RS20340	COG2199	diguanylate cyclase activity
AWU82_RS20350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWU82_RS20355	COG1074	ATP-dependent DNA helicase activity
AWU82_RS20360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AWU82_RS20400	COG3712	iron ion homeostasis
AWU82_RS20405	COG1595	DNA-templated transcription, initiation
AWU82_RS20410	COG0840	transmembrane signaling receptor activity
AWU82_RS20435	COG1802	Transcriptional regulator
AWU82_RS20445	COG5001	Diguanylate cyclase
AWU82_RS20445	COG3300	MHYT domain
AWU82_RS20460	COG1538	Outer membrane efflux protein
AWU82_RS20465	COG2274	protein secretion by the type I secretion system
AWU82_RS20470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS20475	COG2175	clavaminate synthase activity
AWU82_RS20485	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AWU82_RS20490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWU82_RS20515	COG1396	sequence-specific DNA binding
AWU82_RS20520	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AWU82_RS20600	COG0529	Catalyzes the synthesis of activated sulfate
AWU82_RS20615	COG0330	HflC and HflK could
AWU82_RS20640	COG2026	Addiction module toxin, RelE StbE family
AWU82_RS20660	COG1566	PFAM secretion protein HlyD family protein
AWU82_RS20675	COG5339	Protein conserved in bacteria
AWU82_RS20680	COG0457	Tetratricopeptide repeat
AWU82_RS20685	COG1649	PFAM Uncharacterised BCR, COG1649
AWU82_RS20685	COG0726	polysaccharide deacetylase
AWU82_RS20690	COG1215	transferase activity, transferring glycosyl groups
AWU82_RS20710	COG2304	oxidoreductase activity
AWU82_RS20715	COG1595	DNA-templated transcription, initiation
AWU82_RS20735	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS20740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWU82_RS20750	COG2199	diguanylate cyclase activity
AWU82_RS20770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWU82_RS20780	COG4208	sulfate ABC transporter
AWU82_RS20785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWU82_RS20850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWU82_RS20855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWU82_RS20880	COG4771	TonB-dependent receptor
AWU82_RS20920	COG0765	amino acid transport
AWU82_RS20925	COG0765	amino acid transport
AWU82_RS20930	COG1126	abc transporter atp-binding protein
AWU82_RS20935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS20940	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWU82_RS20955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWU82_RS20970	COG2011	ABC-type metal ion transport system permease component
AWU82_RS20975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWU82_RS20980	COG1464	Belongs to the NlpA lipoprotein family
AWU82_RS21005	COG1126	abc transporter atp-binding protein
AWU82_RS21010	COG0765	amino acid transport
AWU82_RS21015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS21020	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AWU82_RS21025	COG1045	serine acetyltransferase
AWU82_RS21030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWU82_RS21045	COG1609	Transcriptional regulator
AWU82_RS21055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWU82_RS21060	COG0667	Aldo Keto reductase
AWU82_RS21065	COG2175	clavaminate synthase activity
AWU82_RS21070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWU82_RS21075	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AWU82_RS21080	COG4521	taurine ABC transporter
AWU82_RS21085	COG2918	glutathione biosynthetic process
AWU82_RS21095	COG2183	response to ionizing radiation
AWU82_RS21110	COG0189	ligase activity
AWU82_RS21115	COG4067	protein conserved in archaea
AWU82_RS21115	COG0189	ligase activity
AWU82_RS21120	COG3287	FIST C domain
AWU82_RS21120	COG2200	EAL domain
AWU82_RS21120	COG2199	diguanylate cyclase activity
AWU82_RS21125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWU82_RS21135	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWU82_RS21140	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWU82_RS21175	COG0514	ATP-dependent DNA helicase (RecQ)
AWU82_RS21180	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWU82_RS21180	COG1024	Enoyl-CoA hydratase
AWU82_RS21195	COG0243	molybdopterin cofactor binding
AWU82_RS21200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWU82_RS21205	COG0583	DNA-binding transcription factor activity
AWU82_RS21210	COG1652	LysM domain
AWU82_RS21215	COG1011	Hydrolase
AWU82_RS21220	COG0494	nUDIX hydrolase
AWU82_RS21225	COG1218	3'(2'),5'-bisphosphate nucleotidase
AWU82_RS21250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWU82_RS21255	COG2957	Belongs to the agmatine deiminase family
AWU82_RS21300	COG1942	4-Oxalocrotonate Tautomerase
AWU82_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS21320	COG1724	mRNA binding
AWU82_RS21325	COG1598	PFAM Uncharacterised protein family UPF0150
AWU82_RS21345	COG0582	viral genome integration into host DNA
AWU82_RS21370	COG4215	(ABC) transporter
AWU82_RS21375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS21420	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AWU82_RS21425	COG1194	a g-specific adenine glycosylase
AWU82_RS21435	COG2223	nitrite transmembrane transporter activity
AWU82_RS21440	COG0131	Imidazoleglycerol-phosphate dehydratase
AWU82_RS21445	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWU82_RS21455	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWU82_RS21460	COG0107	imidazoleglycerol-phosphate synthase activity
AWU82_RS21475	COG2861	carbohydrate metabolic process
AWU82_RS21480	COG0793	Belongs to the peptidase S41A family
AWU82_RS21485	COG4942	peptidase
AWU82_RS21490	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWU82_RS21505	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AWU82_RS21510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWU82_RS21525	COG3852	Histidine kinase
AWU82_RS21545	COG0301	tRNA thio-modification
AWU82_RS21545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWU82_RS21550	COG1217	gtp-binding protein TYPA
AWU82_RS21560	COG0058	SHG alpha-glucan phosphorylase activity
AWU82_RS21575	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AWU82_RS21605	COG3040	lipid binding
AWU82_RS21610	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS21615	COG2188	Transcriptional regulator
AWU82_RS21625	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AWU82_RS21630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWU82_RS21640	COG4176	ABC-type proline glycine betaine transport system permease component
AWU82_RS21645	COG4175	Glycine betaine
AWU82_RS21645	COG0517	IMP dehydrogenase activity
AWU82_RS21650	COG2986	histidine ammonia-lyase
AWU82_RS21655	COG2986	histidine ammonia-lyase
AWU82_RS21660	COG1228	amidohydrolase
AWU82_RS21675	COG0657	acetylesterase activity
AWU82_RS21680	COG0596	Alpha beta hydrolase
AWU82_RS21685	COG1490	D-aminoacyl-tRNA deacylase activity
AWU82_RS21690	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AWU82_RS21695	COG2943	transferase activity, transferring hexosyl groups
AWU82_RS21705	COG0765	amino acid transport
AWU82_RS21715	COG0840	transmembrane signaling receptor activity
AWU82_RS21735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWU82_RS21750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWU82_RS21755	COG0140	phosphoribosyl-ATP diphosphatase activity
AWU82_RS21760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWU82_RS21765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWU82_RS21775	COG2226	methyltransferase
AWU82_RS21820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWU82_RS21825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AWU82_RS21835	COG0018	arginyl-trna synthetase
AWU82_RS21840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWU82_RS21845	COG0254	rRNA binding
AWU82_RS21855	COG0281	malic enzyme
AWU82_RS21890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWU82_RS21895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWU82_RS21905	COG0067	glutamate synthase
AWU82_RS21905	COG0069	glutamate synthase activity
AWU82_RS21905	COG0070	glutamate synthase
AWU82_RS21910	COG0493	'glutamate synthase
AWU82_RS21915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWU82_RS21930	COG2814	Major facilitator Superfamily
AWU82_RS21935	COG0583	DNA-binding transcription factor activity
AWU82_RS21950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWU82_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS21965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWU82_RS21975	COG2226	methyltransferase
AWU82_RS22005	COG2986	histidine ammonia-lyase
AWU82_RS22020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWU82_RS22030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWU82_RS22035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWU82_RS22050	COG1192	Involved in chromosome partitioning
AWU82_RS22055	COG3118	belongs to the thioredoxin family
AWU82_RS22060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AWU82_RS22065	COG3264	Mechanosensitive ion channel
AWU82_RS22065	COG1196	nuclear chromosome segregation
AWU82_RS22070	COG3263	regulation of cellular component size
AWU82_RS22090	COG0840	transmembrane signaling receptor activity
AWU82_RS22095	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS22100	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AWU82_RS22100	COG0506	proline dehydrogenase activity
AWU82_RS22100	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AWU82_RS22105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWU82_RS22125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AWU82_RS22130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWU82_RS22155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AWU82_RS22160	COG0859	PFAM glycosyl transferase family 9
AWU82_RS22165	COG0859	PFAM glycosyl transferase family 9
AWU82_RS22170	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS22200	COG2192	nodulation
AWU82_RS22205	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS22220	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS22225	COG1215	transferase activity, transferring glycosyl groups
AWU82_RS22235	COG1132	(ABC) transporter
AWU82_RS22240	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AWU82_RS22240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWU82_RS22265	COG0667	Aldo Keto reductase
AWU82_RS22285	COG1519	Transferase
AWU82_RS22290	COG1538	Outer membrane efflux protein
AWU82_RS22295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWU82_RS22310	COG0494	nUDIX hydrolase
AWU82_RS22320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWU82_RS22325	COG3150	esterase
AWU82_RS22340	COG3577	Aspartyl protease
AWU82_RS22365	COG1278	Cold shock
AWU82_RS22370	COG0717	Belongs to the dCTP deaminase family
AWU82_RS22385	COG1201	RNA secondary structure unwinding
AWU82_RS22390	COG4598	ABC transporter
AWU82_RS22415	COG1793	dna ligase
AWU82_RS22425	COG2366	antibiotic biosynthetic process
AWU82_RS22430	COG0625	glutathione transferase activity
AWU82_RS22440	COG0653	protein targeting
AWU82_RS22450	COG3012	SEC-C Motif Domain Protein
AWU82_RS22485	COG1199	ATP-dependent helicase activity
AWU82_RS22495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWU82_RS22500	COG2885	chlorophyll binding
AWU82_RS22505	COG0259	pyridoxamine-phosphate oxidase activity
AWU82_RS22530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWU82_RS22540	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AWU82_RS22560	COG0583	DNA-binding transcription factor activity
AWU82_RS22575	COG3220	belongs to the UPF0276 family
AWU82_RS22625	COG2084	Dehydrogenase
AWU82_RS22635	COG0727	PFAM Uncharacterised protein family (UPF0153)
AWU82_RS22640	COG2271	Major facilitator Superfamily
AWU82_RS22645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWU82_RS22665	COG0583	DNA-binding transcription factor activity
AWU82_RS22670	COG0306	phosphate transporter
AWU82_RS22680	COG1414	Transcriptional regulator
AWU82_RS22685	COG2814	Major facilitator Superfamily
AWU82_RS22690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWU82_RS22695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWU82_RS22700	COG0183	Belongs to the thiolase family
AWU82_RS22705	COG3485	protocatechuate 3,4-dioxygenase
AWU82_RS22710	COG3485	protocatechuate 3,4-dioxygenase
AWU82_RS22715	COG0477	Major facilitator Superfamily
AWU82_RS22725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWU82_RS22730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWU82_RS22765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS22775	COG1902	pentaerythritol trinitrate reductase activity
AWU82_RS22780	COG2814	Major facilitator Superfamily
AWU82_RS22820	COG1473	amidohydrolase
AWU82_RS22830	COG0154	amidase activity
AWU82_RS22845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWU82_RS22855	COG1704	LemA family
AWU82_RS22860	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AWU82_RS22875	COG0697	spore germination
AWU82_RS22880	COG0693	protein deglycase activity
AWU82_RS22885	COG3422	double-strand break repair
AWU82_RS22900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWU82_RS22905	COG0235	Class ii aldolase
AWU82_RS22920	COG1454	alcohol dehydrogenase
AWU82_RS22925	COG2814	Major facilitator Superfamily
AWU82_RS22935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AWU82_RS22940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWU82_RS22945	COG2271	Major facilitator Superfamily
AWU82_RS23000	COG4106	trans-aconitate 2-methyltransferase activity
AWU82_RS23030	COG2267	carboxylic ester hydrolase activity
AWU82_RS23055	COG0439	Biotin carboxylase
AWU82_RS23060	COG3665	Urea carboxylase-associated protein
AWU82_RS23115	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWU82_RS23160	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AWU82_RS23190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWU82_RS23195	COG4783	chaperone-mediated protein folding
AWU82_RS23200	COG0425	Belongs to the sulfur carrier protein TusA family
AWU82_RS23205	COG0628	permease
AWU82_RS23210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWU82_RS23220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWU82_RS23225	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AWU82_RS23230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWU82_RS23235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWU82_RS23250	COG3064	Membrane
AWU82_RS23265	COG0463	Glycosyl transferase, family 2
AWU82_RS23300	COG2807	transmembrane transport
AWU82_RS23305	COG2194	sulfuric ester hydrolase activity
AWU82_RS23315	COG3100	YcgL domain-containing protein
AWU82_RS23330	COG2983	Belongs to the UPF0260 family
AWU82_RS23370	COG1770	oligopeptidase
AWU82_RS23380	COG0121	glutamine amidotransferase
AWU82_RS23390	COG0583	DNA-binding transcription factor activity
AWU82_RS23395	COG2814	Major facilitator Superfamily
AWU82_RS23400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWU82_RS23405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWU82_RS23410	COG1984	allophanate hydrolase subunit 2
AWU82_RS23420	COG0542	response to heat
AWU82_RS23440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWU82_RS23470	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AWU82_RS23475	COG1643	Atp-dependent helicase
AWU82_RS23485	COG1595	DNA-templated transcription, initiation
AWU82_RS23495	COG2188	Transcriptional regulator
AWU82_RS23505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWU82_RS23510	COG1132	(ABC) transporter
AWU82_RS23520	COG2267	carboxylic ester hydrolase activity
AWU82_RS23535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWU82_RS23545	COG0583	DNA-binding transcription factor activity
AWU82_RS23550	COG1335	isochorismatase
AWU82_RS23555	COG0668	transmembrane transport
AWU82_RS23560	COG0513	Belongs to the DEAD box helicase family
AWU82_RS23605	COG2996	Protein conserved in bacteria
AWU82_RS23615	COG0697	spore germination
AWU82_RS23625	COG0583	DNA-binding transcription factor activity
AWU82_RS23640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWU82_RS23670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS23710	COG2832	Protein of unknown function (DUF454)
AWU82_RS23735	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWU82_RS23750	COG2207	Transcriptional regulator
AWU82_RS23775	COG3123	guanosine phosphorylase activity
AWU82_RS23795	COG3851	Histidine kinase
AWU82_RS23800	COG2197	response regulator
AWU82_RS23805	COG1597	lipid kinase activity
AWU82_RS23815	COG0303	'Molybdopterin
AWU82_RS23820	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWU82_RS23825	COG0746	molybdenum cofactor guanylyltransferase activity
AWU82_RS23835	COG0564	pseudouridine synthase activity
AWU82_RS23855	COG0004	ammonium transporteR
AWU82_RS23875	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AWU82_RS23885	COG2197	response regulator
AWU82_RS23890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS23890	COG2205	protein histidine kinase activity
AWU82_RS23895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AWU82_RS23900	COG1956	GAF domain-containing protein
AWU82_RS23910	COG2205	protein histidine kinase activity
AWU82_RS23910	COG0784	Response regulator, receiver
AWU82_RS23910	COG5002	protein histidine kinase activity
AWU82_RS23915	COG1846	Transcriptional regulator
AWU82_RS23920	COG0386	Belongs to the glutathione peroxidase family
AWU82_RS23925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWU82_RS23930	COG0436	Aminotransferase
AWU82_RS23935	COG0501	Belongs to the peptidase M48B family
AWU82_RS23940	COG0500	methyltransferase
AWU82_RS23945	COG3384	dioxygenase
AWU82_RS23955	COG1024	Enoyl-CoA hydratase
AWU82_RS23955	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWU82_RS23965	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AWU82_RS23970	COG3214	Protein conserved in bacteria
AWU82_RS23980	COG0583	DNA-binding transcription factor activity
AWU82_RS23990	COG0583	DNA-binding transcription factor activity
AWU82_RS23995	COG1846	Transcriptional regulator
AWU82_RS24000	COG1764	response to oxidative stress
AWU82_RS24010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWU82_RS24025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWU82_RS24045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWU82_RS24075	COG1376	ErfK ybiS ycfS ynhG family protein
AWU82_RS24090	COG4181	ATPase activity
AWU82_RS24095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AWU82_RS24110	COG2259	Doxx family
AWU82_RS24115	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AWU82_RS24120	COG0084	hydrolase, TatD family'
AWU82_RS24160	COG2205	protein histidine kinase activity
AWU82_RS24165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AWU82_RS24175	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AWU82_RS24200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWU82_RS24205	COG4221	oxidoreductase activity
AWU82_RS24210	COG1555	photosystem II stabilization
AWU82_RS24230	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS24230	COG1216	Glycosyl transferase, family 2
AWU82_RS24250	COG0463	Glycosyl transferase, family 2
AWU82_RS24265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWU82_RS24280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWU82_RS24295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AWU82_RS24315	COG0776	regulation of translation
AWU82_RS24330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWU82_RS24335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWU82_RS24340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWU82_RS24350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AWU82_RS24360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWU82_RS24365	COG0402	S-adenosylhomocysteine deaminase activity
AWU82_RS24370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWU82_RS24375	COG0546	phosphoglycolate phosphatase activity
AWU82_RS24380	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS24395	COG5002	protein histidine kinase activity
AWU82_RS24395	COG5001	Diguanylate cyclase
AWU82_RS24415	COG1054	Belongs to the UPF0176 family
AWU82_RS24420	COG0271	Belongs to the BolA IbaG family
AWU82_RS24430	COG0114	fumarate hydratase activity
AWU82_RS24435	COG0697	spore germination
AWU82_RS24445	COG0183	Belongs to the thiolase family
AWU82_RS24450	COG2326	polyphosphate kinase activity
AWU82_RS24455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWU82_RS24455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AWU82_RS24465	COG0367	asparagine synthase
AWU82_RS24470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWU82_RS24470	COG0189	ligase activity
AWU82_RS24480	COG3089	Belongs to the UPF0270 family
AWU82_RS24485	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWU82_RS24490	COG1742	UPF0060 membrane protein
AWU82_RS24500	COG1368	sulfuric ester hydrolase activity
AWU82_RS24520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWU82_RS24525	COG2885	chlorophyll binding
AWU82_RS24555	COG2207	Transcriptional regulator
AWU82_RS24560	COG1064	alcohol dehydrogenase
AWU82_RS24565	COG1414	Transcriptional regulator
AWU82_RS24570	COG2271	Major facilitator Superfamily
AWU82_RS24575	COG4948	Mandelate Racemase Muconate Lactonizing
AWU82_RS24580	COG0800	Aldolase
AWU82_RS24585	COG3734	2-keto-3-deoxy-galactonokinase
AWU82_RS24605	COG1418	mRNA catabolic process
AWU82_RS24625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWU82_RS24635	COG1397	ADP-ribosylglycohydrolase
AWU82_RS24640	COG2188	Transcriptional regulator
AWU82_RS24645	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWU82_RS24650	COG1129	ABC transporter
AWU82_RS24655	COG1879	ABC-type sugar transport system periplasmic component
AWU82_RS24660	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS24670	COG2186	Transcriptional regulator
AWU82_RS24685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWU82_RS24695	COG0084	hydrolase, TatD family'
AWU82_RS24710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWU82_RS24715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWU82_RS24725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWU82_RS24730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWU82_RS24745	COG0416	fatty acid biosynthetic process
AWU82_RS24750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWU82_RS24760	COG0424	maF-like protein
AWU82_RS24765	COG0616	signal peptide processing
AWU82_RS24765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWU82_RS24770	COG0546	phosphoglycolate phosphatase activity
AWU82_RS24780	COG1530	ribonuclease E activity
AWU82_RS24790	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AWU82_RS24790	COG3608	succinylglutamate desuccinylase aspartoacylase
AWU82_RS24805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWU82_RS24810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWU82_RS24815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AWU82_RS24820	COG2835	tetraacyldisaccharide 4'-kinase activity
AWU82_RS24825	COG1663	tetraacyldisaccharide 4'-kinase activity
AWU82_RS24830	COG0848	biopolymer transport protein
AWU82_RS24835	COG0811	peptide transport
AWU82_RS24850	COG0842	Transport permease protein
AWU82_RS24855	COG1131	(ABC) transporter
AWU82_RS24860	COG0625	glutathione transferase activity
AWU82_RS24885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWU82_RS24940	COG0840	transmembrane signaling receptor activity
AWU82_RS24950	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS24955	COG2130	NADP-dependent
AWU82_RS24960	COG0284	orotidine-5'-phosphate decarboxylase activity
AWU82_RS24980	COG0628	permease
AWU82_RS25005	COG1022	Amp-dependent synthetase and ligase
AWU82_RS25020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWU82_RS25025	COG4771	TonB-dependent receptor
AWU82_RS25035	COG0784	Response regulator, receiver
AWU82_RS25035	COG5002	protein histidine kinase activity
AWU82_RS25035	COG2205	protein histidine kinase activity
AWU82_RS25040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWU82_RS25055	COG3122	Protein conserved in bacteria
AWU82_RS25060	COG3956	TIGRFAM MazG family protein
AWU82_RS25065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWU82_RS25070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWU82_RS25090	COG2205	protein histidine kinase activity
AWU82_RS25090	COG0784	Response regulator, receiver
AWU82_RS25090	COG5002	protein histidine kinase activity
AWU82_RS25095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWU82_RS25115	COG3118	belongs to the thioredoxin family
AWU82_RS25120	COG1393	Belongs to the ArsC family
AWU82_RS25135	COG2818	Glycosylase
AWU82_RS25140	COG0037	tRNA processing
AWU82_RS25150	COG3091	SprT-like family
AWU82_RS25155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AWU82_RS25160	COG1301	dicarboxylic acid transport
AWU82_RS25165	COG1917	Cupin 2, conserved barrel domain protein
AWU82_RS25165	COG4977	sequence-specific DNA binding
AWU82_RS25195	COG2205	protein histidine kinase activity
AWU82_RS25200	COG0745	RESPONSE REGULATOR receiver
AWU82_RS25205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWU82_RS25205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWU82_RS25210	COG1749	Flagellar hook protein flgE
AWU82_RS25215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AWU82_RS25225	COG1815	bacterial-type flagellum-dependent cell motility
AWU82_RS25230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWU82_RS25235	COG0835	chemotaxis
AWU82_RS25235	COG0784	Response regulator, receiver
AWU82_RS25245	COG2747	anti-sigma28 factor FlgM
AWU82_RS25255	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AWU82_RS25260	COG0477	Major facilitator Superfamily
AWU82_RS25330	COG2239	Acts as a magnesium transporter
AWU82_RS25360	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWU82_RS25365	COG0527	aspartate kinase activity
AWU82_RS25370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWU82_RS25375	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AWU82_RS25380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWU82_RS25385	COG2988	succinylglutamate desuccinylase activity
AWU82_RS25395	COG3724	N-succinylarginine dihydrolase activity
AWU82_RS25400	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS25415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWU82_RS25455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWU82_RS25465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWU82_RS25525	COG3706	GGDEF domain
AWU82_RS25545	COG0504	CTP synthase activity
AWU82_RS25550	COG2329	Antibiotic biosynthesis monooxygenase
AWU82_RS25560	COG0584	glycerophosphoryl diester phosphodiesterase
AWU82_RS25580	COG0306	phosphate transporter
AWU82_RS25585	COG0583	DNA-binding transcription factor activity
AWU82_RS25590	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS25600	COG0583	DNA-binding transcription factor activity
AWU82_RS25605	COG0583	DNA-binding transcription factor activity
AWU82_RS25610	COG4221	oxidoreductase activity
AWU82_RS25615	COG4941	Belongs to the sigma-70 factor family
AWU82_RS25620	COG3795	YCII-related domain
AWU82_RS25630	COG0456	acetyltransferase
AWU82_RS25655	COG0436	Aminotransferase
AWU82_RS25665	COG3265	gluconokinase activity
AWU82_RS25670	COG1609	Transcriptional regulator
AWU82_RS25675	COG0583	DNA-binding transcription factor activity
AWU82_RS25685	COG2271	Major facilitator Superfamily
AWU82_RS25730	COG0242	peptide deformylase activity
AWU82_RS25735	COG1295	ribonuclease BN
AWU82_RS25740	COG3237	CsbD-like
AWU82_RS25750	COG0318	PFAM AMP-dependent synthetase and ligase
AWU82_RS25765	COG2030	dehydratase
AWU82_RS25775	COG3530	Putative quorum-sensing-regulated virulence factor
AWU82_RS25780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWU82_RS25790	COG0800	Aldolase
AWU82_RS25805	COG1737	Transcriptional regulator
AWU82_RS25810	COG0676	glucose-6-phosphate 1-epimerase activity
AWU82_RS25830	COG1175	transmembrane transport
AWU82_RS25835	COG1653	transport
AWU82_RS25875	COG3712	iron ion homeostasis
AWU82_RS25890	COG2832	Protein of unknown function (DUF454)
AWU82_RS25895	COG0840	transmembrane signaling receptor activity
AWU82_RS25900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AWU82_RS25920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWU82_RS25940	COG0509	glycine decarboxylation via glycine cleavage system
AWU82_RS25945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWU82_RS25945	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWU82_RS25950	COG1760	l-serine dehydratase
AWU82_RS25955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWU82_RS25960	COG1278	Cold shock
AWU82_RS25970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWU82_RS25980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWU82_RS25985	COG0602	queuosine metabolic process
AWU82_RS25990	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AWU82_RS25995	COG2885	chlorophyll binding
AWU82_RS26000	COG0823	Involved in the tonB-independent uptake of proteins
AWU82_RS26020	COG0824	Thioesterase
AWU82_RS26025	COG2255	four-way junction helicase activity
AWU82_RS26030	COG0632	four-way junction helicase activity
AWU82_RS26035	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AWU82_RS26040	COG0217	transcriptional regulatory protein
AWU82_RS26045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWU82_RS26060	COG0783	Belongs to the Dps family
AWU82_RS26070	COG2900	Belongs to the SlyX family
AWU82_RS26085	COG0668	transmembrane transport
AWU82_RS26090	COG1666	GTP binding
AWU82_RS26105	COG2096	Adenosyltransferase
AWU82_RS26110	COG0494	nUDIX hydrolase
AWU82_RS26120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWU82_RS26125	COG0653	protein targeting
AWU82_RS26135	COG0433	COG0433 Predicted ATPase
AWU82_RS26145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWU82_RS26145	COG0438	transferase activity, transferring glycosyl groups
AWU82_RS26170	COG2925	Exonuclease
AWU82_RS26195	COG0714	Associated with various cellular activities
AWU82_RS26245	COG0469	pyruvate kinase activity
AWU82_RS26255	COG1024	Enoyl-CoA hydratase
AWU82_RS26260	COG0633	Ferredoxin
AWU82_RS26265	COG3706	GGDEF domain
AWU82_RS26285	COG4191	Histidine kinase
AWU82_RS26295	COG0477	Major facilitator Superfamily
AWU82_RS26330	COG2207	Transcriptional regulator
AWU82_RS26335	COG3842	ATPase activity
AWU82_RS26355	COG1012	belongs to the aldehyde dehydrogenase family
AWU82_RS26365	COG0583	DNA-binding transcription factor activity
AWU82_RS26370	COG2910	NAD(P)H-binding
AWU82_RS26380	COG0583	DNA-binding transcription factor activity
AWU82_RS26400	COG0477	Major facilitator Superfamily
AWU82_RS26415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWU82_RS26420	COG0583	DNA-binding transcription factor activity
AWU82_RS26435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWU82_RS26465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWU82_RS26470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWU82_RS26480	COG3642	lipopolysaccharide core region biosynthetic process
AWU82_RS26490	COG0642	Histidine kinase
AWU82_RS26505	COG0459	protein refolding
AWU82_RS26510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWU82_RS26525	COG1028	Short-chain dehydrogenase reductase Sdr
AWU82_RS26530	COG0489	protein tyrosine kinase activity
AWU82_RS26535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWU82_RS26535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWU82_RS26545	COG2878	Part of a membrane complex involved in electron transport
AWU82_RS26555	COG4659	FMN binding
AWU82_RS26565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWU82_RS26575	COG2197	response regulator
AWU82_RS26585	COG0137	argininosuccinate synthase activity
AWU82_RS26595	COG0418	dihydroorotase activity
AWU82_RS26600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWU82_RS26605	COG0450	alkyl hydroperoxide reductase
AWU82_RS26620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWU82_RS26625	COG0243	molybdopterin cofactor binding
AWU82_RS26635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWU82_RS26640	COG3842	ATPase activity
AWU82_RS26650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWU82_RS26660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWU82_RS26675	COG0583	DNA-binding transcription factor activity
AWU82_RS26680	COG0477	Major facilitator Superfamily
AWU82_RS26715	COG0814	amino acid
AWU82_RS26720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWU82_RS26725	COG0765	amino acid transport
AWU82_RS26730	COG0765	amino acid transport
AWU82_RS26735	COG1126	abc transporter atp-binding protein
AWU82_RS26755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWU82_RS26765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWU82_RS26770	COG0583	DNA-binding transcription factor activity
AWU82_RS26780	COG1280	lysine exporter protein (LysE YggA)
AWU82_RS26785	COG0494	nUDIX hydrolase
AWU82_RS26795	COG5001	Diguanylate cyclase
AWU82_RS26795	COG3300	MHYT domain
AWU82_RS26805	COG1858	cytochrome C peroxidase
AWU82_RS26810	COG0642	Histidine kinase
AWU82_RS26820	COG0531	amino acid
AWU82_RS26830	COG2197	response regulator
AWU82_RS26835	COG0069	glutamate synthase activity
AWU82_RS26865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWU82_RS26865	COG0546	phosphoglycolate phosphatase activity
AWU82_RS26880	COG1113	amino acid transport
AWU82_RS26925	COG1695	Transcriptional regulator
AWU82_RS26930	COG2375	cellular response to nickel ion
AWU82_RS26940	COG4628	conserved protein (DUF2132)
AWU82_RS26960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWU82_RS26990	COG4106	trans-aconitate 2-methyltransferase activity
AWU82_RS26995	COG0500	methyltransferase
AWU82_RS27000	COG0590	tRNA wobble adenosine to inosine editing
AWU82_RS27015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWU82_RS27015	COG0519	Catalyzes the synthesis of GMP from XMP
AWU82_RS27040	COG1570	exodeoxyribonuclease VII activity
AWU82_RS27045	COG0739	heme binding
AWU82_RS27050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWU82_RS27055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWU82_RS27060	COG0436	Aminotransferase
AWU82_RS27065	COG1160	GTP binding
AWU82_RS27080	COG0124	histidyl-tRNA synthetase
AWU82_RS27085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWU82_RS27090	COG1426	Protein conserved in bacteria
AWU82_RS27100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWU82_RS27105	COG0105	UTP biosynthetic process
AWU82_RS27110	COG2975	iron-sulfur cluster assembly
AWU82_RS27115	COG0633	Ferredoxin
AWU82_RS27120	COG0443	Heat shock 70 kDa protein
AWU82_RS27125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AWU82_RS27130	COG0316	Belongs to the HesB IscA family
AWU82_RS27140	COG1104	cysteine desulfurase activity
AWU82_RS27165	COG3134	Outer membrane lipoprotein
AWU82_RS27180	COG1862	Preprotein translocase
AWU82_RS27185	COG0343	queuine tRNA-ribosyltransferase activity
AWU82_RS27190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWU82_RS27200	COG0582	viral genome integration into host DNA
AWU82_RS27265	COG0464	growth
AWU82_RS27305	COG2161	toxin-antitoxin pair type II binding
AWU82_RS27315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWU82_RS27320	COG0583	DNA-binding transcription factor activity
AWU82_RS27340	COG0109	protoheme IX farnesyltransferase activity
AWU82_RS27350	COG1845	cytochrome c oxidase, subunit III
AWU82_RS27355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWU82_RS27360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWU82_RS27365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AWU82_RS27375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWU82_RS27375	COG1017	nitric oxide dioxygenase activity
AWU82_RS27430	COG5002	protein histidine kinase activity
AWU82_RS27445	COG4251	negative regulation of phosphorylation
AWU82_RS27445	COG3706	GGDEF domain
AWU82_RS27445	COG5001	Diguanylate cyclase
AWU82_RS27445	COG2203	Gaf domain
AWU82_RS27450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AWU82_RS27455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWU82_RS27470	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWU82_RS27475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWU82_RS27480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWU82_RS27485	COG0772	Belongs to the SEDS family
AWU82_RS27490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWU82_RS27495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWU82_RS27500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWU82_RS27505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWU82_RS27520	COG0275	rRNA processing
AWU82_RS27525	COG2001	Belongs to the MraZ family
AWU82_RS27540	COG3107	peptidoglycan biosynthetic process
AWU82_RS27545	COG0792	nuclease activity
AWU82_RS27550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AWU82_RS27555	COG2823	Periplasmic or secreted lipoprotein
AWU82_RS27560	COG2969	positive regulation of protein catabolic process
AWU82_RS27565	COG0625	glutathione transferase activity
AWU82_RS27570	COG2857	Cytochrome c1
AWU82_RS27575	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWU82_RS27580	COG0723	plastoquinol--plastocyanin reductase activity
AWU82_RS27585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWU82_RS27590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWU82_RS27595	COG0667	Aldo Keto reductase
AWU82_RS27600	COG1960	acyl-CoA dehydrogenase activity
AWU82_RS27610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AWU82_RS27615	COG0180	Tryptophanyl-tRNA synthetase
AWU82_RS27635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWU82_RS27660	COG0318	PFAM AMP-dependent synthetase and ligase
AWU82_RS27665	COG1280	lysine exporter protein (LysE YggA)
AWU82_RS27670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWU82_RS27675	COG2813	Specifically methylates the guanine in position
AWU82_RS27680	COG2119	membrane
AWU82_RS27685	COG0501	Belongs to the peptidase M48B family
AWU82_RS27690	COG0840	transmembrane signaling receptor activity
AWU82_RS27695	COG2135	peptidase activity
AWU82_RS27750	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AWU82_RS27755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWU82_RS27765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWU82_RS27770	COG1090	epimerase
AWU82_RS27775	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AWU82_RS27790	COG0789	Transcriptional regulator
AWU82_RS27795	COG0415	Belongs to the DNA photolyase family
AWU82_RS27805	COG4221	oxidoreductase activity
AWU82_RS27820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AWU82_RS27840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWU82_RS27845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWU82_RS27855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWU82_RS27860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWU82_RS27870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AWU82_RS27875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWU82_RS27885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWU82_RS27890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWU82_RS27895	COG0193	aminoacyl-tRNA hydrolase activity
AWU82_RS27905	COG2223	nitrite transmembrane transporter activity
AWU82_RS27935	COG0405	Gamma-glutamyltransferase