locus-tag	class	description
BVH74_RS00025	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BVH74_RS00050	COG0582	viral genome integration into host DNA
BVH74_RS00065	COG4566	intracellular signal transduction
BVH74_RS00070	COG4191	Histidine kinase
BVH74_RS00075	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS00110	COG1024	Enoyl-CoA hydratase
BVH74_RS00115	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS00130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BVH74_RS00140	COG0148	phosphopyruvate hydratase activity
BVH74_RS00145	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BVH74_RS00150	COG0504	CTP synthase activity
BVH74_RS00160	COG0825	malonyl-CoA metabolic process
BVH74_RS00170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVH74_RS00175	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVH74_RS00180	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVH74_RS00185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVH74_RS00190	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVH74_RS00210	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVH74_RS00220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVH74_RS00230	COG0528	UMP kinase activity
BVH74_RS00235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BVH74_RS00240	COG0052	Belongs to the universal ribosomal protein uS2 family
BVH74_RS00245	COG0024	Methionine aminopeptidase
BVH74_RS00255	COG0436	Aminotransferase
BVH74_RS00260	COG1393	Belongs to the ArsC family
BVH74_RS00265	COG2171	N-acyltransferase activity
BVH74_RS00270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVH74_RS00280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVH74_RS00285	COG2226	methyltransferase
BVH74_RS00295	COG1278	Cold shock
BVH74_RS00315	COG1131	(ABC) transporter
BVH74_RS00325	COG0742	ribosomal rna small subunit methyltransferase
BVH74_RS00340	COG1214	PFAM Peptidase M22, glycoprotease
BVH74_RS00350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BVH74_RS00360	COG3956	TIGRFAM MazG family protein
BVH74_RS00365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVH74_RS00385	COG0736	holo-[acyl-carrier-protein] synthase activity
BVH74_RS00400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVH74_RS00405	COG0571	ribonuclease III activity
BVH74_RS00420	COG0481	GTPase activity
BVH74_RS00425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVH74_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BVH74_RS00495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BVH74_RS00505	COG5001	Diguanylate cyclase
BVH74_RS00510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BVH74_RS00520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVH74_RS00555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVH74_RS00580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVH74_RS00580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVH74_RS00605	COG0579	oxidoreductase
BVH74_RS00615	COG4269	membrane
BVH74_RS00620	COG2814	Major facilitator Superfamily
BVH74_RS00625	COG0583	DNA-binding transcription factor activity
BVH74_RS00640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVH74_RS00655	COG0488	(ABC) transporter
BVH74_RS00660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVH74_RS00675	COG5001	Diguanylate cyclase
BVH74_RS00685	COG1970	mechanosensitive ion channel activity
BVH74_RS00690	COG2813	Specifically methylates the guanine in position
BVH74_RS00695	COG1067	ATP-dependent peptidase activity
BVH74_RS00720	COG1280	lysine exporter protein (LysE YggA)
BVH74_RS00725	COG0530	calcium, potassium:sodium antiporter activity
BVH74_RS00730	COG1846	Transcriptional regulator
BVH74_RS00735	COG1764	response to oxidative stress
BVH74_RS00755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVH74_RS00765	COG0335	large ribosomal subunit rRNA binding
BVH74_RS00770	COG0336	Belongs to the RNA methyltransferase TrmD family
BVH74_RS00785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVH74_RS00795	COG4536	flavin adenine dinucleotide binding
BVH74_RS00805	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVH74_RS00820	COG0494	nUDIX hydrolase
BVH74_RS00835	COG1858	cytochrome C peroxidase
BVH74_RS00840	COG3323	Protein of unknown function (DUF1653)
BVH74_RS00840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVH74_RS00880	COG3832	glyoxalase III activity
BVH74_RS00885	COG2329	Antibiotic biosynthesis monooxygenase
BVH74_RS00935	COG0517	IMP dehydrogenase activity
BVH74_RS00940	COG4974	Belongs to the 'phage' integrase family
BVH74_RS00955	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BVH74_RS00980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVH74_RS00985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVH74_RS00990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVH74_RS00995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVH74_RS01000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVH74_RS01020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVH74_RS01025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVH74_RS01030	COG1127	ABC transporter
BVH74_RS01040	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BVH74_RS01050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVH74_RS01055	COG1137	ATPase activity
BVH74_RS01075	COG1660	Displays ATPase and GTPase activities
BVH74_RS01085	COG0312	modulator of DNA gyrase
BVH74_RS01090	COG3028	Belongs to the UPF0307 family
BVH74_RS01140	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS01160	COG1073	alpha beta
BVH74_RS01160	COG2226	methyltransferase
BVH74_RS01165	COG0156	8-amino-7-oxononanoate synthase activity
BVH74_RS01170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BVH74_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVH74_RS01185	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS01190	COG1196	nuclear chromosome segregation
BVH74_RS01190	COG3264	Mechanosensitive ion channel
BVH74_RS01195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVH74_RS01200	COG0400	carboxylic ester hydrolase activity
BVH74_RS01210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BVH74_RS01240	COG3920	Histidine kinase
BVH74_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS01260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVH74_RS01315	COG0795	lipopolysaccharide-transporting ATPase activity
BVH74_RS01320	COG0795	lipopolysaccharide-transporting ATPase activity
BVH74_RS01340	COG0525	valine-tRNA ligase activity
BVH74_RS01345	COG0471	metal ion transport
BVH74_RS01345	COG0490	domain, Protein
BVH74_RS01350	COG3081	Nucleoid-associated protein
BVH74_RS01385	COG0842	Transport permease protein
BVH74_RS01390	COG1131	(ABC) transporter
BVH74_RS01410	COG0312	modulator of DNA gyrase
BVH74_RS01415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVH74_RS01440	COG1792	Involved in formation and maintenance of cell shape
BVH74_RS01445	COG1077	Cell shape determining protein MreB Mrl
BVH74_RS01450	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVH74_RS01455	COG0154	amidase activity
BVH74_RS01460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVH74_RS01470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVH74_RS01495	COG0659	secondary active sulfate transmembrane transporter activity
BVH74_RS01500	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BVH74_RS01505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BVH74_RS01540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVH74_RS01545	COG1280	lysine exporter protein (LysE YggA)
BVH74_RS01550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BVH74_RS01555	COG1090	epimerase
BVH74_RS01560	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BVH74_RS01570	COG0415	Belongs to the DNA photolyase family
BVH74_RS01590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVH74_RS01605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVH74_RS01610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVH74_RS01620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVH74_RS01635	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BVH74_RS01650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVH74_RS01680	COG0473	3-isopropylmalate dehydrogenase activity
BVH74_RS01690	COG0288	reversible hydration of carbon dioxide
BVH74_RS01695	COG0456	acetyltransferase
BVH74_RS01705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVH74_RS01710	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS01740	COG1183	phosphatidylcholine synthase activity
BVH74_RS01745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVH74_RS01755	COG0028	Belongs to the TPP enzyme family
BVH74_RS01765	COG3098	single-species biofilm formation
BVH74_RS01775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVH74_RS01795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVH74_RS01800	COG0069	glutamate synthase activity
BVH74_RS01805	COG2218	PFAM glutamate synthase alpha subunit domain protein
BVH74_RS01810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BVH74_RS01850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BVH74_RS01850	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVH74_RS01875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS01880	COG1309	transcriptional regulator
BVH74_RS01895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVH74_RS01905	COG0848	biopolymer transport protein
BVH74_RS01910	COG0811	peptide transport
BVH74_RS01915	COG3720	iron ion transport
BVH74_RS01940	COG0436	Aminotransferase
BVH74_RS01945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVH74_RS01955	COG4191	Histidine kinase
BVH74_RS01980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BVH74_RS01985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BVH74_RS02010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BVH74_RS02025	COG2203	Gaf domain
BVH74_RS02025	COG3706	GGDEF domain
BVH74_RS02025	COG5001	Diguanylate cyclase
BVH74_RS02025	COG4251	negative regulation of phosphorylation
BVH74_RS02040	COG1030	water channel activity
BVH74_RS02045	COG0330	HflC and HflK could
BVH74_RS02060	COG1185	polyribonucleotide nucleotidyltransferase activity
BVH74_RS02065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BVH74_RS02070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVH74_RS02080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVH74_RS02085	COG0195	Participates in both transcription termination and antitermination
BVH74_RS02090	COG0779	Required for maturation of 30S ribosomal subunits
BVH74_RS02105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVH74_RS02110	COG0149	triose-phosphate isomerase activity
BVH74_RS02115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVH74_RS02120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVH74_RS02125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVH74_RS02130	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BVH74_RS02165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVH74_RS02185	COG0497	DNA recombination
BVH74_RS02200	COG2914	Belongs to the UPF0125 (RnfH) family
BVH74_RS02210	COG0733	neurotransmitter:sodium symporter activity
BVH74_RS02215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVH74_RS02235	COG1715	Restriction endonuclease
BVH74_RS02250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BVH74_RS02265	COG0848	biopolymer transport protein
BVH74_RS02270	COG0811	peptide transport
BVH74_RS02315	COG2197	response regulator
BVH74_RS02325	COG4221	oxidoreductase activity
BVH74_RS02340	COG3046	protein related to deoxyribodipyrimidine photolyase
BVH74_RS02345	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BVH74_RS02350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS02355	COG1129	ABC transporter
BVH74_RS02355	COG0842	Transport permease protein
BVH74_RS02360	COG0842	Transport permease protein
BVH74_RS02385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVH74_RS02395	COG1012	belongs to the aldehyde dehydrogenase family
BVH74_RS02400	COG0519	Catalyzes the synthesis of GMP from XMP
BVH74_RS02400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVH74_RS02420	COG0519	Catalyzes the synthesis of GMP from XMP
BVH74_RS02420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVH74_RS02485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVH74_RS02495	COG0405	Gamma-glutamyltransferase
BVH74_RS02505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVH74_RS02545	COG0071	Belongs to the small heat shock protein (HSP20) family
BVH74_RS02565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVH74_RS02570	COG1074	ATP-dependent DNA helicase activity
BVH74_RS02575	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BVH74_RS02585	COG0174	glutamine synthetase
BVH74_RS02600	COG0019	diaminopimelate decarboxylase activity
BVH74_RS02605	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BVH74_RS02625	COG1309	transcriptional regulator
BVH74_RS02640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVH74_RS02650	COG0583	DNA-binding transcription factor activity
BVH74_RS02655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVH74_RS02660	COG4208	sulfate ABC transporter
BVH74_RS02665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BVH74_RS02690	COG4786	Flagellar basal body rod
BVH74_RS02690	COG1256	bacterial-type flagellum assembly
BVH74_RS02695	COG0741	lytic transglycosylase activity
BVH74_RS02700	COG1706	bacterial-type flagellum-dependent cell motility
BVH74_RS02710	COG4786	Flagellar basal body rod
BVH74_RS02715	COG4787	bacterial-type flagellum-dependent cell motility
BVH74_RS02720	COG1749	Flagellar hook protein flgE
BVH74_RS02725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BVH74_RS02730	COG1558	bacterial-type flagellum-dependent cell motility
BVH74_RS02745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS02750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS02765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVH74_RS02770	COG1191	sigma factor activity
BVH74_RS02795	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BVH74_RS02835	COG1677	Flagellar hook-basal body complex protein FliE
BVH74_RS02860	COG1987	bacterial-type flagellum assembly
BVH74_RS02865	COG1684	flagellar biosynthetic protein fliR
BVH74_RS02870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVH74_RS02915	COG0739	heme binding
BVH74_RS02920	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BVH74_RS02945	COG1981	membrane
BVH74_RS02950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVH74_RS02955	COG0537	adenosine 5'-monophosphoramidase activity
BVH74_RS02960	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BVH74_RS02965	COG1765	OsmC-like protein
BVH74_RS02980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVH74_RS02985	COG0840	transmembrane signaling receptor activity
BVH74_RS02990	COG3300	MHYT domain
BVH74_RS02990	COG5001	Diguanylate cyclase
BVH74_RS03010	COG2132	Multicopper oxidase
BVH74_RS03025	COG0730	response to heat
BVH74_RS03030	COG1722	exodeoxyribonuclease VII activity
BVH74_RS03035	COG0142	geranyltranstransferase activity
BVH74_RS03040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH74_RS03045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS03060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVH74_RS03065	COG2226	methyltransferase
BVH74_RS03080	COG2217	Heavy metal translocating P-type atpase
BVH74_RS03095	COG4206	TonB-dependent receptor
BVH74_RS03130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVH74_RS03140	COG3577	Aspartyl protease
BVH74_RS03145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVH74_RS03160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BVH74_RS03175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVH74_RS03180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVH74_RS03180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVH74_RS03190	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS03195	COG0583	DNA-binding transcription factor activity
BVH74_RS03200	COG2264	protein methyltransferase activity
BVH74_RS03205	COG3118	belongs to the thioredoxin family
BVH74_RS03215	COG1136	(ABC) transporter
BVH74_RS03215	COG0577	efflux transmembrane transporter activity
BVH74_RS03240	COG0848	biopolymer transport protein
BVH74_RS03245	COG0811	peptide transport
BVH74_RS03250	COG0811	peptide transport
BVH74_RS03260	COG3047	cAMP biosynthetic process
BVH74_RS03280	COG2814	Major facilitator Superfamily
BVH74_RS03300	COG0202	RNA polymerase activity
BVH74_RS03305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVH74_RS03310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVH74_RS03320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVH74_RS03330	COG0200	Binds to the 23S rRNA
BVH74_RS03335	COG1841	ribosomal large subunit assembly
BVH74_RS03340	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BVH74_RS03345	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BVH74_RS03350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVH74_RS03355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BVH74_RS03365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BVH74_RS03370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BVH74_RS03375	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVH74_RS03385	COG0255	Belongs to the universal ribosomal protein uL29 family
BVH74_RS03390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVH74_RS03395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BVH74_RS03400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BVH74_RS03405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BVH74_RS03410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVH74_RS03415	COG0089	rRNA binding
BVH74_RS03425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVH74_RS03450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVH74_RS03460	COG0085	RNA polymerase activity
BVH74_RS03465	COG0222	ribosome binding
BVH74_RS03475	COG0081	regulation of translation
BVH74_RS03530	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BVH74_RS03530	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BVH74_RS03535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVH74_RS03565	COG0281	malic enzyme
BVH74_RS03585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVH74_RS03590	COG0018	arginyl-trna synthetase
BVH74_RS03600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BVH74_RS03660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVH74_RS03665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVH74_RS03670	COG0140	phosphoribosyl-ATP diphosphatase activity
BVH74_RS03675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH74_RS03680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH74_RS03700	COG2169	Transcriptional regulator
BVH74_RS03725	COG1490	D-aminoacyl-tRNA deacylase activity
BVH74_RS03815	COG2831	hemolysin activation secretion protein
BVH74_RS03820	COG1217	gtp-binding protein TYPA
BVH74_RS03825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVH74_RS03825	COG0301	tRNA thio-modification
BVH74_RS03840	COG3852	Histidine kinase
BVH74_RS03850	COG1846	Transcriptional regulator
BVH74_RS03855	COG4772	TonB-dependent receptor
BVH74_RS03865	COG4774	siderophore transport
BVH74_RS03870	COG0745	RESPONSE REGULATOR receiver
BVH74_RS03880	COG0745	RESPONSE REGULATOR receiver
BVH74_RS03885	COG5002	protein histidine kinase activity
BVH74_RS03890	COG5002	protein histidine kinase activity
BVH74_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS03900	COG0786	glutamate:sodium symporter activity
BVH74_RS03910	COG0640	Transcriptional regulator
BVH74_RS03925	COG0659	secondary active sulfate transmembrane transporter activity
BVH74_RS03935	COG3909	cytochrome
BVH74_RS03940	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BVH74_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS03960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH74_RS03965	COG0385	Bile acid
BVH74_RS03970	COG2072	flavoprotein involved in K transport
BVH74_RS03980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH74_RS03980	COG3453	Protein conserved in bacteria
BVH74_RS03985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS03990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH74_RS04000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVH74_RS04005	COG0583	DNA-binding transcription factor activity
BVH74_RS04010	COG1335	isochorismatase
BVH74_RS04020	COG1984	allophanate hydrolase subunit 2
BVH74_RS04025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BVH74_RS04055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVH74_RS04060	COG3180	Ammonia monooxygenase
BVH74_RS04095	COG2207	Transcriptional regulator
BVH74_RS04130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVH74_RS04135	COG0251	oxidation-reduction process
BVH74_RS04150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH74_RS04160	COG0700	Nucleoside recognition
BVH74_RS04165	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVH74_RS04220	COG4941	Belongs to the sigma-70 factor family
BVH74_RS04230	COG3795	YCII-related domain
BVH74_RS04235	COG5507	3-demethylubiquinone-9 3-methyltransferase
BVH74_RS04240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BVH74_RS04245	COG0735	belongs to the Fur family
BVH74_RS04250	COG1121	(ABC) transporter
BVH74_RS04255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVH74_RS04270	COG0109	protoheme IX farnesyltransferase activity
BVH74_RS04275	COG1612	heme a metabolic process
BVH74_RS04300	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BVH74_RS04305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVH74_RS04310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BVH74_RS04320	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BVH74_RS04330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVH74_RS04335	COG2130	NADP-dependent
BVH74_RS04340	COG0004	ammonium transporteR
BVH74_RS04370	COG0606	chelatase, subunit chli
BVH74_RS04380	COG0347	Belongs to the P(II) protein family
BVH74_RS04385	COG0004	ammonium transporteR
BVH74_RS04390	COG0432	Pfam Uncharacterised protein family UPF0047
BVH74_RS04395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVH74_RS04405	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS04410	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS04435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVH74_RS04440	COG1116	anion transmembrane transporter activity
BVH74_RS04450	COG1011	Hydrolase
BVH74_RS04480	COG1965	Belongs to the frataxin family
BVH74_RS04490	COG3072	Adenylate cyclase
BVH74_RS04500	COG0625	glutathione transferase activity
BVH74_RS04520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVH74_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
BVH74_RS04580	COG0133	tryptophan synthase activity
BVH74_RS04585	COG0159	tryptophan synthase activity
BVH74_RS04590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVH74_RS04600	COG0009	L-threonylcarbamoyladenylate synthase
BVH74_RS04605	COG0758	DNA mediated transformation
BVH74_RS04610	COG1652	LysM domain
BVH74_RS04620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVH74_RS04625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVH74_RS04630	COG0569	domain protein
BVH74_RS04635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVH74_RS04645	COG1560	Kdo2-lipid A biosynthetic process
BVH74_RS04650	COG2818	Glycosylase
BVH74_RS04695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVH74_RS04705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVH74_RS04710	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BVH74_RS04715	COG0594	ribonuclease P activity
BVH74_RS04720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BVH74_RS04725	COG0706	membrane insertase activity
BVH74_RS04730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVH74_RS04735	COG0402	S-adenosylhomocysteine deaminase activity
BVH74_RS04745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVH74_RS04755	COG0357	Ribosomal RNA small subunit methyltransferase G
BVH74_RS04760	COG1192	Involved in chromosome partitioning
BVH74_RS04765	COG1475	DNA binding
BVH74_RS04770	COG3312	ion transport
BVH74_RS04775	COG0356	it plays a direct role in the translocation of protons across the membrane
BVH74_RS04785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVH74_RS04790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVH74_RS04805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVH74_RS04810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BVH74_RS04820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVH74_RS04835	COG0523	cobalamin synthesis protein
BVH74_RS04840	COG1469	GTP cyclohydrolase I activity
BVH74_RS04895	COG0511	ligase activity, forming carbon-carbon bonds
BVH74_RS04895	COG5016	pyruvate
BVH74_RS04900	COG0439	Biotin carboxylase
BVH74_RS04915	COG3835	regulator
BVH74_RS04920	COG2610	gluconate transmembrane transporter activity
BVH74_RS04925	COG1929	Belongs to the glycerate kinase type-1 family
BVH74_RS04945	COG1429	ligase activity, forming nitrogen-metal bonds
BVH74_RS04950	COG4771	TonB-dependent receptor
BVH74_RS04955	COG1278	Cold shock
BVH74_RS04960	COG0798	PFAM Bile acid sodium symporter
BVH74_RS04965	COG0488	(ABC) transporter
BVH74_RS04970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVH74_RS04975	COG3706	GGDEF domain
BVH74_RS04980	COG1902	pentaerythritol trinitrate reductase activity
BVH74_RS04985	COG0640	Transcriptional regulator
BVH74_RS04995	COG1737	Transcriptional regulator
BVH74_RS05000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVH74_RS05010	COG0583	DNA-binding transcription factor activity
BVH74_RS05015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BVH74_RS05020	COG0010	Belongs to the arginase family
BVH74_RS05030	COG0210	DNA helicase
BVH74_RS05035	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BVH74_RS05045	COG1846	Transcriptional regulator
BVH74_RS05070	COG1607	acyl-coa hydrolase
BVH74_RS05085	COG0581	inorganic phosphate transmembrane transporter activity
BVH74_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVH74_RS05100	COG0640	Transcriptional regulator
BVH74_RS05105	COG0431	NADPH-dependent FMN reductase
BVH74_RS05110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVH74_RS05175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVH74_RS05195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVH74_RS05200	COG1758	RNA polymerase activity
BVH74_RS05220	COG1215	transferase activity, transferring glycosyl groups
BVH74_RS05275	COG1561	YicC-like family, N-terminal region
BVH74_RS05280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BVH74_RS05290	COG0708	Exodeoxyribonuclease III
BVH74_RS05310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVH74_RS05320	COG0756	dUTP diphosphatase activity
BVH74_RS05325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVH74_RS05330	COG2003	Belongs to the UPF0758 family
BVH74_RS05335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVH74_RS05340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVH74_RS05345	COG0739	heme binding
BVH74_RS05360	COG1203	CRISPR-associated helicase, Cas3
BVH74_RS05375	COG1857	crispr-associated protein
BVH74_RS05395	COG1518	maintenance of DNA repeat elements
BVH74_RS05400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVH74_RS05430	COG3706	GGDEF domain
BVH74_RS05435	COG1477	protein flavinylation
BVH74_RS05440	COG1968	undecaprenyl-diphosphatase activity
BVH74_RS05445	COG2239	Acts as a magnesium transporter
BVH74_RS05450	COG0826	peptidase U32
BVH74_RS05490	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS05495	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVH74_RS05495	COG1024	Enoyl-CoA hydratase
BVH74_RS05505	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS05520	COG1881	PFAM PEBP family protein
BVH74_RS05530	COG0183	Belongs to the thiolase family
BVH74_RS05535	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVH74_RS05550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVH74_RS05615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVH74_RS05620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVH74_RS05625	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BVH74_RS05645	COG0429	hydrolase of the alpha beta-hydrolase fold
BVH74_RS05650	COG0742	ribosomal rna small subunit methyltransferase
BVH74_RS05660	COG0612	Peptidase, M16
BVH74_RS05665	COG0552	protein localization to endoplasmic reticulum
BVH74_RS05670	COG2884	Cell division ATP-binding protein ftsE
BVH74_RS05675	COG2177	Part of the ABC transporter FtsEX involved in
BVH74_RS05690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVH74_RS05695	COG2363	Small membrane protein
BVH74_RS05705	COG2022	thiamine diphosphate biosynthetic process
BVH74_RS05710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVH74_RS05750	COG0251	oxidation-reduction process
BVH74_RS05765	COG2814	Major facilitator Superfamily
BVH74_RS05795	COG1024	Enoyl-CoA hydratase
BVH74_RS05805	COG0824	Thioesterase
BVH74_RS05810	COG1454	alcohol dehydrogenase
BVH74_RS05815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVH74_RS05820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BVH74_RS05830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVH74_RS05830	COG2813	Specifically methylates the guanine in position
BVH74_RS05835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVH74_RS05840	COG1872	DUF167
BVH74_RS05895	COG0540	Belongs to the ATCase OTCase family
BVH74_RS05900	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BVH74_RS05905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVH74_RS05910	COG1678	Uncharacterized ACR, COG1678
BVH74_RS05915	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BVH74_RS05920	COG0189	ligase activity
BVH74_RS05950	COG0643	Histidine kinase
BVH74_RS05950	COG2198	Histidine kinase
BVH74_RS05950	COG0784	Response regulator, receiver
BVH74_RS05955	COG2201	protein-glutamate methylesterase activity
BVH74_RS05975	COG2183	response to ionizing radiation
BVH74_RS05985	COG2918	glutathione biosynthetic process
BVH74_RS05995	COG0604	alcohol dehydrogenase
BVH74_RS06000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVH74_RS06010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVH74_RS06165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVH74_RS06205	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS06240	COG1309	transcriptional regulator
BVH74_RS06250	COG1177	transmembrane transport
BVH74_RS06255	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVH74_RS06260	COG3842	ATPase activity
BVH74_RS06280	COG0174	glutamine synthetase
BVH74_RS06285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVH74_RS06290	COG0174	glutamine synthetase
BVH74_RS06295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH74_RS06305	COG3228	Belongs to the MtfA family
BVH74_RS06315	COG2957	Belongs to the agmatine deiminase family
BVH74_RS06325	COG0165	Argininosuccinate lyase
BVH74_RS06330	COG0745	RESPONSE REGULATOR receiver
BVH74_RS06330	COG2972	Histidine kinase
BVH74_RS06370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BVH74_RS06385	COG0248	Ppx GppA phosphatase
BVH74_RS06400	COG3706	GGDEF domain
BVH74_RS06410	COG1671	Belongs to the UPF0178 family
BVH74_RS06415	COG0488	(ABC) transporter
BVH74_RS06435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BVH74_RS06440	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BVH74_RS06450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVH74_RS06460	COG4942	peptidase
BVH74_RS06465	COG0793	Belongs to the peptidase S41A family
BVH74_RS06475	COG0107	imidazoleglycerol-phosphate synthase activity
BVH74_RS06485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BVH74_RS06490	COG0131	Imidazoleglycerol-phosphate dehydratase
BVH74_RS06495	COG0579	oxidoreductase
BVH74_RS06505	COG1194	a g-specific adenine glycosylase
BVH74_RS06510	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BVH74_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVH74_RS06555	COG1228	amidohydrolase
BVH74_RS06560	COG0010	Belongs to the arginase family
BVH74_RS06570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVH74_RS06575	COG2986	histidine ammonia-lyase
BVH74_RS06590	COG2188	Transcriptional regulator
BVH74_RS06595	COG0826	peptidase U32
BVH74_RS06600	COG2272	Belongs to the type-B carboxylesterase lipase family
BVH74_RS06615	COG3706	GGDEF domain
BVH74_RS06615	COG2203	Gaf domain
BVH74_RS06615	COG5001	Diguanylate cyclase
BVH74_RS06615	COG4251	negative regulation of phosphorylation
BVH74_RS06650	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS06655	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS06670	COG1346	cytolysis
BVH74_RS06685	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS06725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVH74_RS06730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BVH74_RS06740	COG0067	glutamate synthase
BVH74_RS06740	COG0069	glutamate synthase activity
BVH74_RS06740	COG0070	glutamate synthase
BVH74_RS06745	COG0493	'glutamate synthase
BVH74_RS06750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BVH74_RS06755	COG1192	Involved in chromosome partitioning
BVH74_RS06765	COG2873	o-acetylhomoserine
BVH74_RS06770	COG0471	metal ion transport
BVH74_RS06770	COG3273	potassium ion transport
BVH74_RS06780	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS06785	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS06790	COG3971	2-oxopent-4-enoate hydratase activity
BVH74_RS06805	COG4181	ATPase activity
BVH74_RS06810	COG0577	efflux transmembrane transporter activity
BVH74_RS06825	COG2996	Protein conserved in bacteria
BVH74_RS06845	COG0358	DNA primase activity
BVH74_RS06850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVH74_RS06855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVH74_RS06860	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVH74_RS06865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVH74_RS06875	COG0617	tRNA 3'-terminal CCA addition
BVH74_RS06880	COG2719	SpoVR family
BVH74_RS06885	COG2718	Belongs to the UPF0229 family
BVH74_RS06890	COG2766	serine protein kinase
BVH74_RS06895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVH74_RS06925	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BVH74_RS06935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVH74_RS06940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BVH74_RS06950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVH74_RS06975	COG0134	indole-3-glycerol-phosphate synthase activity
BVH74_RS06980	COG3038	cytochrome b561
BVH74_RS06985	COG2353	YceI-like domain
BVH74_RS06990	COG4607	ABC-type enterochelin transport system periplasmic component
BVH74_RS06995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVH74_RS07000	COG4605	iron ion homeostasis
BVH74_RS07005	COG4604	ABC transporter, ATP-binding protein
BVH74_RS07010	COG0583	DNA-binding transcription factor activity
BVH74_RS07015	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS07030	COG2186	Transcriptional regulator
BVH74_RS07035	COG1620	l-lactate permease
BVH74_RS07055	COG4589	Belongs to the CDS family
BVH74_RS07080	COG0513	Belongs to the DEAD box helicase family
BVH74_RS07085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVH74_RS07100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVH74_RS07105	COG0500	methyltransferase
BVH74_RS07110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVH74_RS07115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVH74_RS07120	COG0126	phosphoglycerate kinase activity
BVH74_RS07140	COG2133	pyrroloquinoline quinone binding
BVH74_RS07150	COG3273	potassium ion transport
BVH74_RS07150	COG0471	metal ion transport
BVH74_RS07155	COG0513	Belongs to the DEAD box helicase family
BVH74_RS07160	COG3706	GGDEF domain
BVH74_RS07165	COG2197	response regulator
BVH74_RS07175	COG0686	Belongs to the AlaDH PNT family
BVH74_RS07180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVH74_RS07185	COG0204	Acyl-transferase
BVH74_RS07200	COG0217	transcriptional regulatory protein
BVH74_RS07270	COG1683	Conserved Protein
BVH74_RS07285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVH74_RS07290	COG0277	FAD linked oxidase domain protein
BVH74_RS07295	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVH74_RS07305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BVH74_RS07310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVH74_RS07315	COG3706	GGDEF domain
BVH74_RS07315	COG2203	Gaf domain
BVH74_RS07315	COG4251	negative regulation of phosphorylation
BVH74_RS07315	COG5001	Diguanylate cyclase
BVH74_RS07325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVH74_RS07350	COG0006	proline dipeptidase activity
BVH74_RS07355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVH74_RS07360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVH74_RS07370	COG1178	ABC-type Fe3 transport system permease component
BVH74_RS07380	COG0509	glycine decarboxylation via glycine cleavage system
BVH74_RS07385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVH74_RS07385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVH74_RS07390	COG2205	protein histidine kinase activity
BVH74_RS07395	COG0745	RESPONSE REGULATOR receiver
BVH74_RS07405	COG2304	oxidoreductase activity
BVH74_RS07410	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BVH74_RS07415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVH74_RS07425	COG2267	carboxylic ester hydrolase activity
BVH74_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS07445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVH74_RS07450	COG2205	protein histidine kinase activity
BVH74_RS07455	COG0745	RESPONSE REGULATOR receiver
BVH74_RS07460	COG0569	domain protein
BVH74_RS07465	COG0517	IMP dehydrogenase activity
BVH74_RS07480	COG2205	protein histidine kinase activity
BVH74_RS07480	COG2202	Pas domain
BVH74_RS07500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVH74_RS07505	COG0494	nUDIX hydrolase
BVH74_RS07520	COG0730	response to heat
BVH74_RS07525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVH74_RS07530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BVH74_RS07545	COG0129	dihydroxy-acid dehydratase activity
BVH74_RS07550	COG5583	Uncharacterized small protein (DUF2292)
BVH74_RS07555	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BVH74_RS07565	COG4208	sulfate ABC transporter
BVH74_RS07570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVH74_RS07575	COG0625	glutathione transferase activity
BVH74_RS07580	COG0121	glutamine amidotransferase
BVH74_RS07585	COG3829	transcription factor binding
BVH74_RS07600	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BVH74_RS07600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVH74_RS07605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVH74_RS07615	COG0306	phosphate transporter
BVH74_RS07620	COG1392	Phosphate transport regulator
BVH74_RS07625	COG3025	triphosphatase activity
BVH74_RS07630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVH74_RS07635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVH74_RS07640	COG3268	Saccharopine dehydrogenase
BVH74_RS07670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVH74_RS07680	COG0494	nUDIX hydrolase
BVH74_RS07685	COG1011	Hydrolase
BVH74_RS07695	COG4067	protein conserved in archaea
BVH74_RS07695	COG0189	ligase activity
BVH74_RS07700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVH74_RS07710	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BVH74_RS07730	COG2814	Major facilitator Superfamily
BVH74_RS07735	COG1252	NADH dehydrogenase
BVH74_RS07760	COG4191	Histidine kinase
BVH74_RS07765	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BVH74_RS07780	COG0300	oxidoreductase activity
BVH74_RS07790	COG0084	hydrolase, TatD family'
BVH74_RS07800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVH74_RS07805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BVH74_RS07810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVH74_RS07810	COG1116	anion transmembrane transporter activity
BVH74_RS07815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVH74_RS07820	COG1116	anion transmembrane transporter activity
BVH74_RS07830	COG4191	Histidine kinase
BVH74_RS07870	COG1802	Transcriptional regulator
BVH74_RS07875	COG0439	Biotin carboxylase
BVH74_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS07915	COG0183	Belongs to the thiolase family
BVH74_RS07920	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS07935	COG0477	Major facilitator Superfamily
BVH74_RS07945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH74_RS07950	COG2885	chlorophyll binding
BVH74_RS07955	COG0204	Acyl-transferase
BVH74_RS07965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVH74_RS07975	COG1309	transcriptional regulator
BVH74_RS07995	COG0492	ferredoxin-NADP+ reductase activity
BVH74_RS08010	COG0343	queuine tRNA-ribosyltransferase activity
BVH74_RS08015	COG1862	Preprotein translocase
BVH74_RS08045	COG1045	serine acetyltransferase
BVH74_RS08055	COG0105	UTP biosynthetic process
BVH74_RS08075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BVH74_RS08080	COG0124	histidyl-tRNA synthetase
BVH74_RS08095	COG1160	GTP binding
BVH74_RS08105	COG0739	heme binding
BVH74_RS08110	COG1570	exodeoxyribonuclease VII activity
BVH74_RS08130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVH74_RS08130	COG3218	ABC-type transport auxiliary lipoprotein component
BVH74_RS08135	COG1127	ABC transporter
BVH74_RS08140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVH74_RS08160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVH74_RS08170	COG0667	Aldo Keto reductase
BVH74_RS08175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVH74_RS08180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVH74_RS08185	COG0723	plastoquinol--plastocyanin reductase activity
BVH74_RS08190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BVH74_RS08195	COG2857	Cytochrome c1
BVH74_RS08200	COG0625	glutathione transferase activity
BVH74_RS08205	COG2969	positive regulation of protein catabolic process
BVH74_RS08210	COG2823	Periplasmic or secreted lipoprotein
BVH74_RS08220	COG0792	nuclease activity
BVH74_RS08240	COG4770	biotin carboxylase activity
BVH74_RS08250	COG3665	Urea carboxylase-associated protein
BVH74_RS08275	COG0275	rRNA processing
BVH74_RS08295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVH74_RS08300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVH74_RS08305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BVH74_RS08310	COG0772	Belongs to the SEDS family
BVH74_RS08315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVH74_RS08320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVH74_RS08325	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVH74_RS08355	COG0739	heme binding
BVH74_RS08365	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVH74_RS08410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVH74_RS08420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVH74_RS08425	COG2252	PERMEase
BVH74_RS08430	COG0545	Peptidyl-prolyl cis-trans isomerase
BVH74_RS08435	COG0142	geranyltranstransferase activity
BVH74_RS08445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVH74_RS08455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVH74_RS08460	COG0268	Binds directly to 16S ribosomal RNA
BVH74_RS08465	COG0728	peptidoglycan biosynthetic process
BVH74_RS08470	COG0196	riboflavin kinase activity
BVH74_RS08475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVH74_RS08480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BVH74_RS08485	COG1047	Peptidyl-prolyl cis-trans
BVH74_RS08490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVH74_RS08495	COG0352	thiamine-phosphate diphosphorylase activity
BVH74_RS08505	COG0237	dephospho-CoA kinase activity
BVH74_RS08530	COG4969	Belongs to the N-Me-Phe pilin family
BVH74_RS08575	COG0583	DNA-binding transcription factor activity
BVH74_RS08585	COG0473	3-isopropylmalate dehydrogenase activity
BVH74_RS08605	COG0436	Aminotransferase
BVH74_RS08640	COG0859	PFAM glycosyl transferase family 9
BVH74_RS08645	COG0438	transferase activity, transferring glycosyl groups
BVH74_RS08670	COG2192	nodulation
BVH74_RS08675	COG0438	transferase activity, transferring glycosyl groups
BVH74_RS08690	COG0438	transferase activity, transferring glycosyl groups
BVH74_RS08710	COG1218	3'(2'),5'-bisphosphate nucleotidase
BVH74_RS08715	COG1132	(ABC) transporter
BVH74_RS08720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BVH74_RS08720	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BVH74_RS08735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVH74_RS08745	COG0667	Aldo Keto reductase
BVH74_RS08755	COG1519	Transferase
BVH74_RS08760	COG1538	Outer membrane efflux protein
BVH74_RS08770	COG0494	nUDIX hydrolase
BVH74_RS08775	COG3151	Protein conserved in bacteria
BVH74_RS08780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVH74_RS08795	COG3577	Aspartyl protease
BVH74_RS08810	COG3830	Belongs to the UPF0237 family
BVH74_RS08810	COG0560	Phosphoserine phosphatase
BVH74_RS08815	COG5001	Diguanylate cyclase
BVH74_RS08825	COG1509	lysine 2,3-aminomutase activity
BVH74_RS08830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVH74_RS08835	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BVH74_RS08840	COG0688	phosphatidylethanolamine metabolic process
BVH74_RS08865	COG1162	GTPase activity
BVH74_RS08870	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BVH74_RS08880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVH74_RS08880	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVH74_RS08885	COG0802	atpase or kinase
BVH74_RS08890	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVH74_RS08895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVH74_RS08905	COG1923	regulation of RNA biosynthetic process
BVH74_RS08910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVH74_RS08915	COG0330	HflC and HflK could
BVH74_RS08920	COG0330	HflC and HflK could
BVH74_RS08930	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BVH74_RS08945	COG0557	exoribonuclease II activity
BVH74_RS08950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVH74_RS08955	COG0360	Binds together with S18 to 16S ribosomal RNA
BVH74_RS08970	COG0359	binds to the 23S rRNA
BVH74_RS08975	COG0305	Participates in initiation and elongation during chromosome replication
BVH74_RS08985	COG2205	protein histidine kinase activity
BVH74_RS08985	COG0784	Response regulator, receiver
BVH74_RS08985	COG5002	protein histidine kinase activity
BVH74_RS08990	COG0151	Belongs to the GarS family
BVH74_RS08995	COG0138	bifunctional purine biosynthesis protein purh
BVH74_RS09015	COG2264	protein methyltransferase activity
BVH74_RS09030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BVH74_RS09050	COG0023	Translation Initiation Factor
BVH74_RS09055	COG0534	Mate efflux family protein
BVH74_RS09060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVH74_RS09075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVH74_RS09080	COG2011	ABC-type metal ion transport system permease component
BVH74_RS09090	COG0205	6-phosphofructokinase activity
BVH74_RS09095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVH74_RS09120	COG0586	Pfam SNARE associated Golgi protein
BVH74_RS09130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BVH74_RS09135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVH74_RS09150	COG0768	penicillin binding
BVH74_RS09155	COG0772	Belongs to the SEDS family
BVH74_RS09160	COG2951	lytic endotransglycosylase activity
BVH74_RS09170	COG1686	Belongs to the peptidase S11 family
BVH74_RS09175	COG2921	Belongs to the UPF0250 family
BVH74_RS09180	COG0321	lipoyl(octanoyl) transferase activity
BVH74_RS09185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVH74_RS09190	COG2951	lytic endotransglycosylase activity
BVH74_RS09205	COG0659	secondary active sulfate transmembrane transporter activity
BVH74_RS09210	COG0589	response to stress
BVH74_RS09230	COG0495	leucyl-tRNA aminoacylation
BVH74_RS09240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BVH74_RS09245	COG4535	Mg2 and Co2 transporter CorC
BVH74_RS09255	COG1702	phosphate starvation-inducible protein PhoH
BVH74_RS09260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVH74_RS09280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BVH74_RS09285	COG0352	thiamine-phosphate diphosphorylase activity
BVH74_RS09290	COG0352	thiamine-phosphate diphosphorylase activity
BVH74_RS09290	COG0351	phosphomethylpyrimidine kinase
BVH74_RS09310	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS09315	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS09330	COG1522	sequence-specific DNA binding
BVH74_RS09345	COG1643	Atp-dependent helicase
BVH74_RS09350	COG2813	Specifically methylates the guanine in position
BVH74_RS09355	COG2119	membrane
BVH74_RS09370	COG1288	antiporter activity
BVH74_RS09375	COG2235	arginine
BVH74_RS09380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVH74_RS09410	COG2897	thiosulfate sulfurtransferase activity
BVH74_RS09415	COG2391	methyltransferase activity
BVH74_RS09425	COG0840	transmembrane signaling receptor activity
BVH74_RS09455	COG3133	Outer membrane lipoprotein
BVH74_RS09460	COG2111	Na H antiporter
BVH74_RS09460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVH74_RS09465	COG1006	Multisubunit Na H antiporter MnhC subunit
BVH74_RS09470	COG0651	ATP synthesis coupled electron transport
BVH74_RS09485	COG1320	monovalent cation:proton antiporter activity
BVH74_RS09490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVH74_RS09490	COG2111	Na H antiporter
BVH74_RS09495	COG1006	Multisubunit Na H antiporter MnhC subunit
BVH74_RS09500	COG0651	ATP synthesis coupled electron transport
BVH74_RS09505	COG1863	multisubunit Na H antiporter MnhE subunit
BVH74_RS09510	COG2212	antiporter activity
BVH74_RS09515	COG1320	monovalent cation:proton antiporter activity
BVH74_RS09520	COG2885	chlorophyll binding
BVH74_RS09565	COG3639	organic phosphonate transmembrane transporter activity
BVH74_RS09575	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BVH74_RS09580	COG3622	Belongs to the hyi family
BVH74_RS09605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS09610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS09615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS09620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS09635	COG1516	flagellar protein fliS
BVH74_RS09740	COG1987	bacterial-type flagellum assembly
BVH74_RS09745	COG1684	flagellar biosynthetic protein fliR
BVH74_RS09760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVH74_RS09800	COG0527	aspartate kinase activity
BVH74_RS09805	COG0662	Cupin 2, conserved barrel domain protein
BVH74_RS09810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVH74_RS09835	COG3706	GGDEF domain
BVH74_RS09845	COG0840	transmembrane signaling receptor activity
BVH74_RS09850	COG2267	carboxylic ester hydrolase activity
BVH74_RS09855	COG0840	transmembrane signaling receptor activity
BVH74_RS09865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BVH74_RS09880	COG2356	endonuclease I
BVH74_RS09885	COG1024	Enoyl-CoA hydratase
BVH74_RS09885	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVH74_RS09895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVH74_RS09910	COG0628	permease
BVH74_RS09930	COG1393	Belongs to the ArsC family
BVH74_RS09940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVH74_RS09965	COG2900	Belongs to the SlyX family
BVH74_RS09975	COG0783	Belongs to the Dps family
BVH74_RS09980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVH74_RS09995	COG0632	four-way junction helicase activity
BVH74_RS10000	COG2255	four-way junction helicase activity
BVH74_RS10005	COG0824	Thioesterase
BVH74_RS10025	COG0823	Involved in the tonB-independent uptake of proteins
BVH74_RS10030	COG2885	chlorophyll binding
BVH74_RS10035	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BVH74_RS10040	COG0602	queuosine metabolic process
BVH74_RS10045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVH74_RS10055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVH74_RS10060	COG4783	chaperone-mediated protein folding
BVH74_RS10065	COG0425	Belongs to the sulfur carrier protein TusA family
BVH74_RS10075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVH74_RS10115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH74_RS10120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH74_RS10130	COG3031	protein transport across the cell outer membrane
BVH74_RS10210	COG0545	Peptidyl-prolyl cis-trans isomerase
BVH74_RS10220	COG5001	Diguanylate cyclase
BVH74_RS10220	COG3300	MHYT domain
BVH74_RS10230	COG0604	alcohol dehydrogenase
BVH74_RS10230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVH74_RS10230	COG3321	synthase
BVH74_RS10230	COG4221	oxidoreductase activity
BVH74_RS10235	COG1362	aminopeptidase activity
BVH74_RS10240	COG0564	pseudouridine synthase activity
BVH74_RS10245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BVH74_RS10250	COG2894	cell division
BVH74_RS10255	COG0850	regulation of cytokinetic process
BVH74_RS10260	COG1560	Kdo2-lipid A biosynthetic process
BVH74_RS10270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVH74_RS10320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVH74_RS10325	COG0527	aspartate kinase activity
BVH74_RS10345	COG2239	Acts as a magnesium transporter
BVH74_RS10350	COG3630	sodium ion export across plasma membrane
BVH74_RS10355	COG0511	ligase activity, forming carbon-carbon bonds
BVH74_RS10355	COG5016	pyruvate
BVH74_RS10360	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BVH74_RS10375	COG0477	Major facilitator Superfamily
BVH74_RS10380	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BVH74_RS10400	COG0835	chemotaxis
BVH74_RS10400	COG0784	Response regulator, receiver
BVH74_RS10405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVH74_RS10410	COG1815	bacterial-type flagellum-dependent cell motility
BVH74_RS10420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BVH74_RS10430	COG4787	bacterial-type flagellum-dependent cell motility
BVH74_RS10445	COG1706	bacterial-type flagellum-dependent cell motility
BVH74_RS10460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVH74_RS10475	COG2217	Heavy metal translocating P-type atpase
BVH74_RS10480	COG0589	response to stress
BVH74_RS10500	COG2925	Exonuclease
BVH74_RS10515	COG0617	tRNA 3'-terminal CCA addition
BVH74_RS10515	COG0517	IMP dehydrogenase activity
BVH74_RS10515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BVH74_RS10535	COG2366	antibiotic biosynthetic process
BVH74_RS10540	COG3634	alkyl hydroperoxide reductase activity
BVH74_RS10550	COG0826	peptidase U32
BVH74_RS10555	COG0826	peptidase U32
BVH74_RS10560	COG3154	lipid carrier protein
BVH74_RS10570	COG0697	spore germination
BVH74_RS10585	COG0271	Belongs to the BolA IbaG family
BVH74_RS10590	COG1054	Belongs to the UPF0176 family
BVH74_RS10605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS10615	COG1538	Outer membrane efflux protein
BVH74_RS10630	COG5001	Diguanylate cyclase
BVH74_RS10630	COG3300	MHYT domain
BVH74_RS10645	COG0514	ATP-dependent DNA helicase (RecQ)
BVH74_RS10650	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVH74_RS10695	COG0745	RESPONSE REGULATOR receiver
BVH74_RS10705	COG2350	Protein conserved in bacteria
BVH74_RS10710	COG0613	PHP domain protein
BVH74_RS10715	COG0009	L-threonylcarbamoyladenylate synthase
BVH74_RS10720	COG0180	Tryptophanyl-tRNA synthetase
BVH74_RS10730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVH74_RS10745	COG3706	GGDEF domain
BVH74_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS10755	COG0546	phosphoglycolate phosphatase activity
BVH74_RS10765	COG0402	S-adenosylhomocysteine deaminase activity
BVH74_RS10770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BVH74_RS10780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVH74_RS10790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVH74_RS10795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVH74_RS10800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BVH74_RS10810	COG0776	regulation of translation
BVH74_RS10820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BVH74_RS10825	COG0284	orotidine-5'-phosphate decarboxylase activity
BVH74_RS10830	COG1063	alcohol dehydrogenase
BVH74_RS10840	COG2906	2 iron, 2 sulfur cluster binding
BVH74_RS10875	COG4221	oxidoreductase activity
BVH74_RS10885	COG1047	Peptidyl-prolyl cis-trans
BVH74_RS10890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVH74_RS10895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVH74_RS10905	COG3842	ATPase activity
BVH74_RS10915	COG0243	molybdopterin cofactor binding
BVH74_RS10920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVH74_RS10925	COG0303	'Molybdopterin
BVH74_RS10930	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVH74_RS10935	COG0746	molybdenum cofactor guanylyltransferase activity
BVH74_RS10945	COG4772	TonB-dependent receptor
BVH74_RS10955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVH74_RS10965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVH74_RS10970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVH74_RS10980	COG0840	transmembrane signaling receptor activity
BVH74_RS10990	COG2814	Major facilitator Superfamily
BVH74_RS10995	COG0183	Belongs to the thiolase family
BVH74_RS11000	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS11005	COG3145	DNA-N1-methyladenine dioxygenase activity
BVH74_RS11015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVH74_RS11025	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS11030	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS11045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVH74_RS11100	COG0513	Belongs to the DEAD box helicase family
BVH74_RS11110	COG1596	polysaccharide export
BVH74_RS11115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BVH74_RS11140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH74_RS11145	COG1682	transport, permease protein
BVH74_RS11155	COG0457	Tetratricopeptide repeat
BVH74_RS11160	COG1216	Glycosyl transferase, family 2
BVH74_RS11180	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BVH74_RS11190	COG0463	Glycosyl transferase, family 2
BVH74_RS11200	COG0529	Catalyzes the synthesis of activated sulfate
BVH74_RS11205	COG3273	potassium ion transport
BVH74_RS11205	COG0471	metal ion transport
BVH74_RS11215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVH74_RS11245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVH74_RS11270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVH74_RS11275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVH74_RS11280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVH74_RS11300	COG2226	methyltransferase
BVH74_RS11310	COG4991	sh3 domain protein
BVH74_RS11315	COG1611	Belongs to the LOG family
BVH74_RS11320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVH74_RS11340	COG2207	Transcriptional regulator
BVH74_RS11350	COG4302	ethanolamine ammonia-lyase activity
BVH74_RS11355	COG0531	amino acid
BVH74_RS11360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVH74_RS11415	COG2207	Transcriptional regulator
BVH74_RS11420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVH74_RS11425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVH74_RS11425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVH74_RS11430	COG0745	RESPONSE REGULATOR receiver
BVH74_RS11435	COG2205	protein histidine kinase activity
BVH74_RS11455	COG0583	DNA-binding transcription factor activity
BVH74_RS11460	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BVH74_RS11470	COG0425	Belongs to the sulfur carrier protein TusA family
BVH74_RS11485	COG3101	peptidyl-lysine hydroxylation
BVH74_RS11495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVH74_RS11520	COG0436	Aminotransferase
BVH74_RS11525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVH74_RS11530	COG0386	Belongs to the glutathione peroxidase family
BVH74_RS11535	COG2205	protein histidine kinase activity
BVH74_RS11535	COG0784	Response regulator, receiver
BVH74_RS11535	COG5002	protein histidine kinase activity
BVH74_RS11585	COG2814	Major facilitator Superfamily
BVH74_RS11590	COG1131	(ABC) transporter
BVH74_RS11595	COG0842	Transport permease protein
BVH74_RS11600	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVH74_RS11600	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVH74_RS11610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVH74_RS11615	COG2853	Lipoprotein
BVH74_RS11625	COG0745	RESPONSE REGULATOR receiver
BVH74_RS11635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVH74_RS11640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVH74_RS11645	COG2815	serine threonine protein kinase
BVH74_RS11645	COG0515	serine threonine protein kinase
BVH74_RS11650	COG0631	protein serine/threonine phosphatase activity
BVH74_RS11705	COG2204	response regulator
BVH74_RS11750	COG0433	COG0433 Predicted ATPase
BVH74_RS11765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH74_RS11770	COG3091	SprT-like family
BVH74_RS11805	COG0037	tRNA processing
BVH74_RS11815	COG0791	NLP P60 protein
BVH74_RS11855	COG0167	dihydroorotate dehydrogenase activity
BVH74_RS11860	COG3130	regulation of translation
BVH74_RS11865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVH74_RS11865	COG0116	Belongs to the methyltransferase superfamily
BVH74_RS11880	COG0084	hydrolase, TatD family'
BVH74_RS11890	COG0435	Glutathione S-transferase
BVH74_RS11900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BVH74_RS11905	COG4181	ATPase activity
BVH74_RS11930	COG2610	gluconate transmembrane transporter activity
BVH74_RS11945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVH74_RS11985	COG2186	Transcriptional regulator
BVH74_RS12010	COG2079	MmgE PrpD family protein
BVH74_RS12260	COG4695	Portal protein
BVH74_RS12265	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVH74_RS12275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BVH74_RS12280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVH74_RS12290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVH74_RS12300	COG4172	Belongs to the ABC transporter superfamily
BVH74_RS12305	COG4239	(ABC) transporter, permease
BVH74_RS12310	COG4174	ABC transporter (Permease)
BVH74_RS12315	COG4166	transmembrane transport
BVH74_RS12320	COG4166	transmembrane transport
BVH74_RS12325	COG1388	LysM domain
BVH74_RS12325	COG0741	lytic transglycosylase activity
BVH74_RS12330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH74_RS12340	COG0328	RNA-DNA hybrid ribonuclease activity
BVH74_RS12350	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVH74_RS12355	COG1024	Enoyl-CoA hydratase
BVH74_RS12365	COG2816	NAD+ diphosphatase activity
BVH74_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS12390	COG0616	signal peptide processing
BVH74_RS12395	COG0604	alcohol dehydrogenase
BVH74_RS12410	COG0741	lytic transglycosylase activity
BVH74_RS12440	COG2204	response regulator
BVH74_RS12470	COG1450	Type ii and iii secretion system protein
BVH74_RS12525	COG5002	protein histidine kinase activity
BVH74_RS12535	COG3447	MASE1 domain protein
BVH74_RS12535	COG5002	protein histidine kinase activity
BVH74_RS12535	COG5001	Diguanylate cyclase
BVH74_RS12595	COG3267	Type II secretory pathway component ExeA
BVH74_RS12595	COG3409	Peptidoglycan-binding domain 1 protein
BVH74_RS12670	COG0640	Transcriptional regulator
BVH74_RS12695	COG2369	cell adhesion
BVH74_RS12795	COG4245	von Willebrand factor, type A
BVH74_RS12805	COG1335	isochorismatase
BVH74_RS12810	COG1280	lysine exporter protein (LysE YggA)
BVH74_RS12825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVH74_RS12855	COG0534	Mate efflux family protein
BVH74_RS12865	COG0316	Belongs to the HesB IscA family
BVH74_RS12865	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BVH74_RS12870	COG0835	chemotaxis
BVH74_RS12870	COG0784	Response regulator, receiver
BVH74_RS12880	COG0488	(ABC) transporter
BVH74_RS12885	COG0589	response to stress
BVH74_RS12890	COG1024	Enoyl-CoA hydratase
BVH74_RS12890	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVH74_RS12895	COG0183	Belongs to the thiolase family
BVH74_RS12935	COG1376	ErfK ybiS ycfS ynhG family protein
BVH74_RS12945	COG0668	transmembrane transport
BVH74_RS12960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVH74_RS12975	COG1805	sodium ion transport
BVH74_RS12990	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVH74_RS13000	COG1477	protein flavinylation
BVH74_RS13010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVH74_RS13015	COG0584	glycerophosphoryl diester phosphodiesterase
BVH74_RS13045	COG2333	competence protein COMEC
BVH74_RS13045	COG0658	competence protein
BVH74_RS13050	COG0811	peptide transport
BVH74_RS13055	COG0848	biopolymer transport protein
BVH74_RS13060	COG1663	tetraacyldisaccharide 4'-kinase activity
BVH74_RS13065	COG2835	tetraacyldisaccharide 4'-kinase activity
BVH74_RS13070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BVH74_RS13075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVH74_RS13085	COG1530	ribonuclease E activity
BVH74_RS13095	COG0546	phosphoglycolate phosphatase activity
BVH74_RS13110	COG1399	metal-binding, possibly nucleic acid-binding protein
BVH74_RS13115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BVH74_RS13125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVH74_RS13135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVH74_RS13140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVH74_RS13145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVH74_RS13150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVH74_RS13170	COG0084	hydrolase, TatD family'
BVH74_RS13175	COG1104	cysteine desulfurase activity
BVH74_RS13180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BVH74_RS13185	COG3842	ATPase activity
BVH74_RS13195	COG1177	transmembrane transport
BVH74_RS13210	COG2272	Belongs to the type-B carboxylesterase lipase family
BVH74_RS13240	COG1322	Protein conserved in bacteria
BVH74_RS13245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVH74_RS13255	COG0714	Associated with various cellular activities
BVH74_RS13275	COG2824	Alkylphosphonate utilization operon protein PhnA
BVH74_RS13280	COG3171	Protein conserved in bacteria
BVH74_RS13365	COG2226	methyltransferase
BVH74_RS13380	COG0583	DNA-binding transcription factor activity
BVH74_RS13420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVH74_RS13435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BVH74_RS13440	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BVH74_RS13445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVH74_RS13455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVH74_RS13460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVH74_RS13465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BVH74_RS13470	COG1648	precorrin-2 dehydrogenase activity
BVH74_RS13470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVH74_RS13475	COG0598	Magnesium transport protein CorA
BVH74_RS13485	COG0505	Belongs to the CarA family
BVH74_RS13490	COG1966	Carbon starvation protein
BVH74_RS13500	COG0003	Pfam Anion-transporting ATPase
BVH74_RS13510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS13525	COG3706	GGDEF domain
BVH74_RS13540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVH74_RS13550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVH74_RS13555	COG2920	part of a sulfur-relay system
BVH74_RS13590	COG2267	carboxylic ester hydrolase activity
BVH74_RS13610	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BVH74_RS13615	COG1215	transferase activity, transferring glycosyl groups
BVH74_RS13635	COG2194	sulfuric ester hydrolase activity
BVH74_RS13650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVH74_RS13655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVH74_RS13660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVH74_RS13665	COG0215	cysteine-tRNA ligase activity
BVH74_RS13675	COG0727	PFAM Uncharacterised protein family (UPF0153)
BVH74_RS13685	COG2308	Evidence 4 Homologs of previously reported genes of
BVH74_RS13695	COG2308	Evidence 4 Homologs of previously reported genes of
BVH74_RS13720	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS13735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVH74_RS13740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVH74_RS13740	COG0517	IMP dehydrogenase activity
BVH74_RS13775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVH74_RS13910	COG4774	siderophore transport
BVH74_RS13915	COG3708	Transcriptional regulator
BVH74_RS13915	COG2207	Transcriptional regulator
BVH74_RS13940	COG1136	(ABC) transporter
BVH74_RS13955	COG3360	Dodecin
BVH74_RS13960	COG0676	glucose-6-phosphate 1-epimerase activity
BVH74_RS13995	COG1473	amidohydrolase
BVH74_RS14000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVH74_RS14010	COG2911	Protein conserved in bacteria
BVH74_RS14015	COG0729	surface antigen
BVH74_RS14020	COG0708	Exodeoxyribonuclease III
BVH74_RS14025	COG0542	response to heat
BVH74_RS14030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVH74_RS14035	COG1278	Cold shock
BVH74_RS14050	COG0482	sulfurtransferase activity
BVH74_RS14055	COG2915	High frequency lysogenization protein hflD homolog
BVH74_RS14060	COG0697	spore germination
BVH74_RS14070	COG2850	peptidyl-arginine hydroxylation
BVH74_RS14105	COG0668	transmembrane transport
BVH74_RS14115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVH74_RS14125	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BVH74_RS14130	COG0583	DNA-binding transcription factor activity
BVH74_RS14140	COG4771	TonB-dependent receptor
BVH74_RS14145	COG3135	benzoate transporter
BVH74_RS14150	COG5001	Diguanylate cyclase
BVH74_RS14150	COG4251	negative regulation of phosphorylation
BVH74_RS14150	COG3706	GGDEF domain
BVH74_RS14150	COG2203	Gaf domain
BVH74_RS14170	COG2203	Gaf domain
BVH74_RS14170	COG2199	diguanylate cyclase activity
BVH74_RS14175	COG2166	iron-sulfur cluster assembly
BVH74_RS14190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVH74_RS14195	COG0719	Fe-S assembly protein
BVH74_RS14200	COG0396	ATPase activity
BVH74_RS14205	COG0719	Fe-S assembly protein
BVH74_RS14225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BVH74_RS14245	COG1115	amino acid carrier protein
BVH74_RS14260	COG0519	Catalyzes the synthesis of GMP from XMP
BVH74_RS14260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVH74_RS14275	COG0174	glutamine synthetase
BVH74_RS14280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BVH74_RS14295	COG3530	Putative quorum-sensing-regulated virulence factor
BVH74_RS14310	COG0628	permease
BVH74_RS14330	COG0640	Transcriptional regulator
BVH74_RS14360	COG1451	nucleotide metabolic process
BVH74_RS14370	COG2807	transmembrane transport
BVH74_RS14375	COG1902	pentaerythritol trinitrate reductase activity
BVH74_RS14390	COG1309	transcriptional regulator
BVH74_RS14410	COG0776	regulation of translation
BVH74_RS14415	COG0072	phenylalanine-tRNA ligase activity
BVH74_RS14420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVH74_RS14435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVH74_RS14440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVH74_RS14465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVH74_RS14515	COG1643	Atp-dependent helicase
BVH74_RS14520	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS14525	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS14535	COG2030	dehydratase
BVH74_RS14545	COG0542	response to heat
BVH74_RS14550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVH74_RS14555	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BVH74_RS14560	COG1278	Cold shock
BVH74_RS14590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVH74_RS14600	COG0662	Cupin 2, conserved barrel domain protein
BVH74_RS14600	COG2207	Transcriptional regulator
BVH74_RS14605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVH74_RS14615	COG2226	methyltransferase
BVH74_RS14620	COG0500	methyltransferase
BVH74_RS14640	COG3106	COG3106 Predicted ATPase
BVH74_RS14650	COG0720	synthase
BVH74_RS14655	COG3100	YcgL domain-containing protein
BVH74_RS14670	COG1596	polysaccharide export
BVH74_RS14670	COG1555	photosystem II stabilization
BVH74_RS14685	COG1286	toxin biosynthetic process
BVH74_RS14695	COG0285	dihydrofolate synthase activity
BVH74_RS14705	COG0159	tryptophan synthase activity
BVH74_RS14745	COG0066	3-isopropylmalate dehydratase activity
BVH74_RS14750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BVH74_RS14770	COG0583	DNA-binding transcription factor activity
BVH74_RS14795	COG2814	Major facilitator Superfamily
BVH74_RS14800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVH74_RS14860	COG1022	Amp-dependent synthetase and ligase
BVH74_RS14865	COG2062	phosphohistidine phosphatase, SixA
BVH74_RS14875	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BVH74_RS14890	COG5002	protein histidine kinase activity
BVH74_RS14890	COG2205	protein histidine kinase activity
BVH74_RS14890	COG0784	Response regulator, receiver
BVH74_RS14895	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS14900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVH74_RS14910	COG0840	transmembrane signaling receptor activity
BVH74_RS14915	COG2814	Major facilitator Superfamily
BVH74_RS14920	COG0733	neurotransmitter:sodium symporter activity
BVH74_RS14925	COG1132	(ABC) transporter
BVH74_RS14930	COG1595	DNA-templated transcription, initiation
BVH74_RS14935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVH74_RS14945	COG0438	transferase activity, transferring glycosyl groups
BVH74_RS14965	COG2267	carboxylic ester hydrolase activity
BVH74_RS15010	COG0840	transmembrane signaling receptor activity
BVH74_RS15050	COG0583	DNA-binding transcription factor activity
BVH74_RS15055	COG2259	Doxx family
BVH74_RS15060	COG3384	dioxygenase
BVH74_RS15110	COG0252	asparaginase activity
BVH74_RS15120	COG1115	amino acid carrier protein
BVH74_RS15145	COG1944	ATP diphosphatase activity
BVH74_RS15165	COG0456	acetyltransferase
BVH74_RS15180	COG0583	DNA-binding transcription factor activity
BVH74_RS15210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVH74_RS15210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVH74_RS15220	COG2878	Part of a membrane complex involved in electron transport
BVH74_RS15230	COG4658	electron transport chain
BVH74_RS15235	COG4659	FMN binding
BVH74_RS15240	COG4660	Part of a membrane complex involved in electron transport
BVH74_RS15245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVH74_RS15265	COG2853	Lipoprotein
BVH74_RS15280	COG0737	Belongs to the 5'-nucleotidase family
BVH74_RS15300	COG0137	argininosuccinate synthase activity
BVH74_RS15310	COG1902	pentaerythritol trinitrate reductase activity
BVH74_RS15310	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVH74_RS15325	COG0406	alpha-ribazole phosphatase activity
BVH74_RS15340	COG1492	cobalamin metabolic process
BVH74_RS15355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVH74_RS15360	COG0778	Nitroreductase
BVH74_RS15365	COG1797	cobyrinic acid a,c-diamide synthase activity
BVH74_RS15380	COG4206	TonB-dependent receptor
BVH74_RS15385	COG1116	anion transmembrane transporter activity
BVH74_RS15390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVH74_RS15395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVH74_RS15400	COG3707	response regulator
BVH74_RS15405	COG1132	(ABC) transporter
BVH74_RS15410	COG1120	ATPase activity
BVH74_RS15415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVH74_RS15430	COG0789	Transcriptional regulator
BVH74_RS15470	COG2259	Doxx family
BVH74_RS15475	COG3048	D-serine ammonia-lyase activity
BVH74_RS15485	COG3122	Protein conserved in bacteria
BVH74_RS15490	COG0189	ligase activity
BVH74_RS15490	COG4067	protein conserved in archaea
BVH74_RS15495	COG0840	transmembrane signaling receptor activity
BVH74_RS15500	COG2056	Na+-H+ antiporter family
BVH74_RS15515	COG3287	FIST C domain
BVH74_RS15515	COG2200	EAL domain
BVH74_RS15515	COG2199	diguanylate cyclase activity
BVH74_RS15530	COG0714	Associated with various cellular activities
BVH74_RS15545	COG2304	oxidoreductase activity
BVH74_RS15565	COG4447	cellulose binding
BVH74_RS15570	COG0308	aminopeptidase N
BVH74_RS15580	COG3139	Protein of unknown function (DUF1315)
BVH74_RS15600	COG0705	Rhomboid family
BVH74_RS15605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVH74_RS15625	COG0418	dihydroorotase activity
BVH74_RS15630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVH74_RS15635	COG2358	TRAP transporter, solute receptor (TAXI family
BVH74_RS15650	COG1116	anion transmembrane transporter activity
BVH74_RS15650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVH74_RS15655	COG2197	response regulator
BVH74_RS15660	COG2223	nitrite transmembrane transporter activity
BVH74_RS15665	COG2815	serine threonine protein kinase
BVH74_RS15665	COG0515	serine threonine protein kinase
BVH74_RS15670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVH74_RS15675	COG2146	nitrite reductase [NAD(P)H] activity
BVH74_RS15680	COG0243	molybdopterin cofactor binding
BVH74_RS15690	COG5265	(ABC) transporter
BVH74_RS15695	COG0659	secondary active sulfate transmembrane transporter activity
BVH74_RS15700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH74_RS15720	COG0583	DNA-binding transcription factor activity
BVH74_RS15730	COG0326	Molecular chaperone. Has ATPase activity
BVH74_RS15800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BVH74_RS15805	COG2009	succinate dehydrogenase
BVH74_RS15820	COG2084	Dehydrogenase
BVH74_RS15865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVH74_RS15870	COG0583	DNA-binding transcription factor activity
BVH74_RS15900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BVH74_RS15905	COG1132	(ABC) transporter
BVH74_RS15910	COG0697	spore germination
BVH74_RS15920	COG0589	response to stress
BVH74_RS15930	COG0717	Belongs to the dCTP deaminase family
BVH74_RS15935	COG0489	protein tyrosine kinase activity
BVH74_RS15940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BVH74_RS15945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BVH74_RS15950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BVH74_RS15960	COG3278	Belongs to the heme-copper respiratory oxidase family
BVH74_RS15975	COG2010	Cytochrome c
BVH74_RS15990	COG2217	Heavy metal translocating P-type atpase
BVH74_RS16010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVH74_RS16020	COG2814	Major facilitator Superfamily
BVH74_RS16025	COG2197	response regulator
BVH74_RS16030	COG0784	Response regulator, receiver
BVH74_RS16030	COG2205	protein histidine kinase activity
BVH74_RS16040	COG2130	NADP-dependent
BVH74_RS16085	COG0519	Catalyzes the synthesis of GMP from XMP
BVH74_RS16100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BVH74_RS16115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVH74_RS16120	COG3115	cell septum assembly
BVH74_RS16135	COG0471	metal ion transport
BVH74_RS16145	COG3088	subunit of a heme lyase
BVH74_RS16155	COG1138	Cytochrome C-type biogenesis protein
BVH74_RS16160	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BVH74_RS16190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVH74_RS16200	COG0835	chemotaxis
BVH74_RS16210	COG1192	Involved in chromosome partitioning
BVH74_RS16220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVH74_RS16230	COG2198	Histidine kinase
BVH74_RS16230	COG0643	Histidine kinase
BVH74_RS16230	COG0784	Response regulator, receiver
BVH74_RS16235	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BVH74_RS16270	COG3287	FIST C domain
BVH74_RS16270	COG2200	EAL domain
BVH74_RS16270	COG2199	diguanylate cyclase activity
BVH74_RS16280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVH74_RS16305	COG0840	transmembrane signaling receptor activity
BVH74_RS16310	COG0477	Major facilitator Superfamily
BVH74_RS16325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVH74_RS16340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVH74_RS16380	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS16385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVH74_RS16390	COG0596	Alpha beta hydrolase
BVH74_RS16405	COG2814	Major facilitator Superfamily
BVH74_RS16415	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS16420	COG1053	succinate dehydrogenase
BVH74_RS16420	COG3976	FMN-binding domain protein
BVH74_RS16420	COG0431	NADPH-dependent FMN reductase
BVH74_RS16430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BVH74_RS16435	COG2086	electron transfer activity
BVH74_RS16440	COG3976	FMN-binding domain protein
BVH74_RS16440	COG1053	succinate dehydrogenase
BVH74_RS16450	COG1053	succinate dehydrogenase
BVH74_RS16475	COG3604	Transcriptional regulator
BVH74_RS16500	COG2832	Protein of unknown function (DUF454)
BVH74_RS16510	COG2223	nitrite transmembrane transporter activity
BVH74_RS16525	COG2181	nitrate reductase activity
BVH74_RS16530	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BVH74_RS16535	COG1140	nitrate reductase beta subunit
BVH74_RS16540	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BVH74_RS16545	COG2223	nitrite transmembrane transporter activity
BVH74_RS16555	COG2223	nitrite transmembrane transporter activity
BVH74_RS16565	COG2197	response regulator
BVH74_RS16575	COG0303	'Molybdopterin
BVH74_RS16580	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVH74_RS16595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BVH74_RS16615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVH74_RS16620	COG0789	Transcriptional regulator
BVH74_RS16625	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS16630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVH74_RS16635	COG1024	Enoyl-CoA hydratase
BVH74_RS16650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVH74_RS16660	COG2154	pterin-4-alpha-carbinolamine dehydratase
BVH74_RS16665	COG1741	Belongs to the pirin family
BVH74_RS16670	COG1741	Belongs to the pirin family
BVH74_RS16675	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BVH74_RS16675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH74_RS16685	COG3089	Belongs to the UPF0270 family
BVH74_RS16725	COG3851	Histidine kinase
BVH74_RS16745	COG1131	(ABC) transporter
BVH74_RS16760	COG2205	protein histidine kinase activity
BVH74_RS16760	COG0784	Response regulator, receiver
BVH74_RS16775	COG1025	Belongs to the peptidase M16 family
BVH74_RS16780	COG2198	Histidine kinase
BVH74_RS16780	COG0784	Response regulator, receiver
BVH74_RS16780	COG2205	protein histidine kinase activity
BVH74_RS16790	COG0348	domain, Protein
BVH74_RS16790	COG3901	Regulator of nitric oxide reductase transcription
BVH74_RS16795	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS16800	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS16805	COG0583	DNA-binding transcription factor activity
BVH74_RS16820	COG2149	membrane
BVH74_RS16845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVH74_RS16855	COG0348	domain, Protein
BVH74_RS16860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVH74_RS16865	COG0385	Bile acid
BVH74_RS16885	COG1253	flavin adenine dinucleotide binding
BVH74_RS16900	COG3276	selenocysteine insertion sequence binding
BVH74_RS16905	COG1921	L-seryl-tRNASec selenium transferase activity
BVH74_RS16945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVH74_RS16950	COG3214	Protein conserved in bacteria
BVH74_RS16975	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BVH74_RS16985	COG4221	oxidoreductase activity
BVH74_RS16990	COG2207	Transcriptional regulator
BVH74_RS17005	COG0535	radical SAM domain protein
BVH74_RS17015	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BVH74_RS17020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVH74_RS17030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVH74_RS17040	COG2267	carboxylic ester hydrolase activity
BVH74_RS17045	COG1012	belongs to the aldehyde dehydrogenase family
BVH74_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
BVH74_RS17060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVH74_RS17065	COG2186	Transcriptional regulator
BVH74_RS17080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVH74_RS17085	COG0840	transmembrane signaling receptor activity
BVH74_RS17090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVH74_RS17115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVH74_RS17125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVH74_RS17135	COG0798	PFAM Bile acid sodium symporter
BVH74_RS17145	COG5002	protein histidine kinase activity
BVH74_RS17150	COG2204	response regulator
BVH74_RS17165	COG0500	methyltransferase
BVH74_RS17170	COG3263	regulation of cellular component size
BVH74_RS17175	COG0800	Aldolase
BVH74_RS17190	COG0469	pyruvate kinase activity
BVH74_RS17225	COG3706	GGDEF domain
BVH74_RS17235	COG1024	Enoyl-CoA hydratase
BVH74_RS17275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH74_RS17280	COG0583	DNA-binding transcription factor activity
BVH74_RS17305	COG1704	LemA family
BVH74_RS17310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS17315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH74_RS17335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVH74_RS17340	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVH74_RS17345	COG0585	pseudouridine synthase activity
BVH74_RS17350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BVH74_RS17360	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BVH74_RS17365	COG0583	DNA-binding transcription factor activity
BVH74_RS17370	COG0004	ammonium transporteR
BVH74_RS17380	COG4191	Histidine kinase
BVH74_RS17395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH74_RS17400	COG0577	efflux transmembrane transporter activity
BVH74_RS17400	COG1136	(ABC) transporter
BVH74_RS17435	COG1309	transcriptional regulator
BVH74_RS17455	COG1024	Enoyl-CoA hydratase
BVH74_RS17480	COG3706	GGDEF domain
BVH74_RS17485	COG2020	methyltransferase activity
BVH74_RS17525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVH74_RS17530	COG0410	ABC transporter
BVH74_RS17555	COG0784	Response regulator, receiver
BVH74_RS17555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVH74_RS17555	COG2198	Histidine kinase
BVH74_RS17555	COG2205	protein histidine kinase activity
BVH74_RS17570	COG1024	Enoyl-CoA hydratase
BVH74_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17605	COG0183	Belongs to the thiolase family
BVH74_RS17620	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17630	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17635	COG0183	Belongs to the thiolase family
BVH74_RS17640	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17645	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17650	COG1024	Enoyl-CoA hydratase
BVH74_RS17655	COG2070	2-Nitropropane dioxygenase
BVH74_RS17660	COG1024	Enoyl-CoA hydratase
BVH74_RS17715	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS17720	COG1902	pentaerythritol trinitrate reductase activity
BVH74_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17745	COG2267	carboxylic ester hydrolase activity
BVH74_RS17760	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BVH74_RS17760	COG0778	Nitroreductase
BVH74_RS17765	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BVH74_RS17770	COG1920	GTP binding
BVH74_RS17775	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BVH74_RS17780	COG0175	sulfate reduction
BVH74_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVH74_RS17820	COG2814	Major facilitator Superfamily
BVH74_RS17825	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17830	COG0318	PFAM AMP-dependent synthetase and ligase
BVH74_RS17835	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17840	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17860	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17865	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17880	COG1960	acyl-CoA dehydrogenase activity
BVH74_RS17885	COG2030	dehydratase
BVH74_RS17900	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS17945	COG1012	belongs to the aldehyde dehydrogenase family
BVH74_RS17950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVH74_RS17965	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BVH74_RS17970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVH74_RS17975	COG2814	Major facilitator Superfamily
BVH74_RS18020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BVH74_RS18025	COG0784	Response regulator, receiver
BVH74_RS18025	COG2198	Histidine kinase
BVH74_RS18025	COG2205	protein histidine kinase activity
BVH74_RS18045	COG3148	PFAM DTW domain containing protein
BVH74_RS18055	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BVH74_RS18065	COG2137	regulation of response to DNA damage stimulus
BVH74_RS18075	COG1546	Belongs to the CinA family
BVH74_RS18195	COG0740	serine-type endopeptidase activity
BVH74_RS18200	COG4695	Portal protein
BVH74_RS18295	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BVH74_RS18305	COG0582	viral genome integration into host DNA
BVH74_RS18315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BVH74_RS18320	COG3706	GGDEF domain
BVH74_RS18330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BVH74_RS18335	COG3030	protein affecting phage T7 exclusion by the F plasmid
BVH74_RS18340	COG1028	Short-chain dehydrogenase reductase Sdr
BVH74_RS18350	COG3695	enzyme binding
BVH74_RS18360	COG0668	transmembrane transport
BVH74_RS18365	COG1666	GTP binding
BVH74_RS18370	COG0745	RESPONSE REGULATOR receiver
BVH74_RS18380	COG2096	Adenosyltransferase
BVH74_RS18395	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVH74_RS18405	COG1115	amino acid carrier protein
BVH74_RS18420	COG0546	phosphoglycolate phosphatase activity
BVH74_RS18425	COG1946	Acyl-CoA thioesterase
BVH74_RS18430	COG0123	including yeast histone deacetylase and acetoin utilization protein
BVH74_RS18440	COG0300	oxidoreductase activity
BVH74_RS18455	COG1199	ATP-dependent helicase activity
BVH74_RS18465	COG3012	SEC-C Motif Domain Protein
BVH74_RS18495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVH74_RS18590	COG0616	signal peptide processing
BVH74_RS18650	COG4197	protein conserved in bacteria, prophage-related