locus-tag	class	description
E3Z27_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E3Z27_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E3Z27_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3Z27_RS00030	ENOG4105ETX	regulatoR
E3Z27_RS00035	ENOG4105BZU	Histidine kinase
E3Z27_RS00045	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
E3Z27_RS00050	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E3Z27_RS00055	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E3Z27_RS00060	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E3Z27_RS00075	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
E3Z27_RS00095	ENOG4105D01	(LipO)protein
E3Z27_RS00100	ENOG4108UMI	ABC transporter, permease
E3Z27_RS00105	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS00125	ENOG4105FAV	ABC, transporter
E3Z27_RS00130	ENOG4105FDK	ABC transporter
E3Z27_RS00135	ENOG4105MYN	Zinc uptake regulation protein
E3Z27_RS00140	ENOG4105NXV	High-affinity zinc uptake system protein
E3Z27_RS00155	ENOG4105C2M	dna polymerase I
E3Z27_RS00160	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E3Z27_RS00170	ENOG4106RE7	Cytochrome
E3Z27_RS00175	ENOG4108Z33	Thiol disulfide Interchange Protein
E3Z27_RS00185	ENOG4105BZU	Histidine kinase
E3Z27_RS00190	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E3Z27_RS00195	ENOG41066DG	(EAL) domain protein
E3Z27_RS00200	ENOG4105ES5	Histidine kinase
E3Z27_RS00205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS00220	ENOG4108ZGU	inhibitor of vertebrate lysozyme
E3Z27_RS00225	ENOG4105CK2	sodium dicarboxylate symporter
E3Z27_RS00240	ENOG4107RAN	Peptidase, M16
E3Z27_RS00245	ENOG4105EAM	Na Pi-cotransporter
E3Z27_RS00250	ENOG4105EE5	Membrane protein terC
E3Z27_RS00255	ENOG4105D4T	Citrate transporter
E3Z27_RS00275	ENOG4105CBG	Sulfatase
E3Z27_RS00290	ENOG4105E2X	shikimate dehydrogenase
E3Z27_RS00295	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E3Z27_RS00300	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E3Z27_RS00305	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3Z27_RS00310	ENOG4105C79	DNA protecting protein DprA
E3Z27_RS00320	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3Z27_RS00325	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E3Z27_RS00330	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E3Z27_RS00335	ENOG4105C1A	potassium transporter peripheral membrane
E3Z27_RS00340	ENOG4105WAP	TPR repeat-containing protein
E3Z27_RS00355	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3Z27_RS00360	ENOG4105E0F	Histidine kinase
E3Z27_RS00460	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E3Z27_RS00485	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
E3Z27_RS00490	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
E3Z27_RS00515	ENOG4105CHH	sulfate transporter
E3Z27_RS00535	ENOG4105DGW	oligopeptidase A
E3Z27_RS00540	ENOG4105VKU	nucleicacid-binding protein
E3Z27_RS00545	ENOG4105DGW	oligopeptidase A
E3Z27_RS00550	ENOG4108Z0R	Transferase
E3Z27_RS00555	ENOG4107XGZ	Hydrolase
E3Z27_RS00580	ENOG4108Z9K	Osmotically inducible protein
E3Z27_RS00585	ENOG4105DEN	Luciferase family
E3Z27_RS00595	ENOG4105WKW	Pfam:DUF1458
E3Z27_RS00610	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E3Z27_RS00615	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E3Z27_RS00645	ENOG4105CYC	Transferase
E3Z27_RS00650	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E3Z27_RS00655	ENOG4105W8H	transhydrogenase (subunit alpha
E3Z27_RS00660	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E3Z27_RS00665	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS00670	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS00720	ENOG4107BJW	polysaccharide deacetylase
E3Z27_RS00725	ENOG4105CND	Glycosyl transferase, family 2
E3Z27_RS00745	ENOG4105CSH	Transporter
E3Z27_RS00750	ENOG4105CR8	Transcriptional regulator
E3Z27_RS00760	ENOG4105CP2	von willebrand factor, type a
E3Z27_RS00765	ENOG4105K6V	RNA polymerase
E3Z27_RS00785	ENOG4105C26	Dehydrogenase
E3Z27_RS00790	ENOG4108JPW	Aminotransferase
E3Z27_RS00795	ENOG4105BZU	Histidine kinase
E3Z27_RS00800	ENOG4105BZU	Histidine kinase
E3Z27_RS00810	ENOG4105BZU	Histidine kinase
E3Z27_RS00820	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E3Z27_RS00825	ENOG4108I5D	sulfate abc transporter
E3Z27_RS00830	ENOG4105ECW	sulfate abc transporter
E3Z27_RS00835	ENOG4108IJ6	ABC transporter
E3Z27_RS00875	ENOG4108ZX5	transcriptional regulator
E3Z27_RS00895	ENOG4108SF5	RNA Polymerase
E3Z27_RS00900	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS00925	ENOG4105DRR	Transcriptional regulator, GntR family
E3Z27_RS00935	ENOG4105BZU	Histidine kinase
E3Z27_RS00960	ENOG4105DFG	type I secretion outer membrane protein
E3Z27_RS00965	ENOG4108JJA	ABC, transporter
E3Z27_RS00980	ENOG4105ECP	epimerase
E3Z27_RS00990	ENOG4108NSC	Pfam:DUF88
E3Z27_RS01075	ENOG4108JU7	Transcriptional regulator
E3Z27_RS01090	ENOG4105D01	(LipO)protein
E3Z27_RS01105	ENOG4105BZS	acriflavin resistance protein
E3Z27_RS01115	ENOG4105W1Y	Transcriptional regulator
E3Z27_RS01120	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E3Z27_RS01125	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E3Z27_RS01130	ENOG4105HF0	Membrane
E3Z27_RS01140	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E3Z27_RS01145	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3Z27_RS01160	ENOG4105C7B	Threonine dehydratase
E3Z27_RS01165	ENOG4105E66	phosphoriboisomerase A
E3Z27_RS01170	ENOG4108ZK4	sdia-regulated domain-containing protein
E3Z27_RS01175	ENOG4108ZK4	sdia-regulated domain-containing protein
E3Z27_RS01180	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E3Z27_RS01185	ENOG4105CQB	FAD linked oxidase domain protein
E3Z27_RS01190	ENOG4108JQ1	Dehydrogenase
E3Z27_RS01200	ENOG4105EAB	amino acid AbC transporter
E3Z27_RS01210	ENOG4108UMI	ABC transporter, permease
E3Z27_RS01215	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS01220	ENOG4105D01	(LipO)protein
E3Z27_RS01235	ENOG4107T8P	acyl-Coa dehydrogenase
E3Z27_RS01245	ENOG4105CDA	abc transporter atp-binding protein
E3Z27_RS01250	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS01255	ENOG4105EAB	amino acid AbC transporter
E3Z27_RS01260	ENOG4105K6H	D-cysteine desulfhydrase
E3Z27_RS01265	ENOG4105C94	Transporter
E3Z27_RS01290	ENOG4105CPC	Aldo Keto reductase
E3Z27_RS01295	ENOG4105E2B	Taurine dioxygenase
E3Z27_RS01300	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS01305	ENOG4108IY8	ABC, transporter
E3Z27_RS01310	ENOG4106FTQ	Taurine ABC transporter, periplasmic
E3Z27_RS01315	ENOG4105D9M	gamma-glutamylcysteine synthetase
E3Z27_RS01325	ENOG4105BZM	domain protein
E3Z27_RS01330	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3Z27_RS01335	ENOG4105E0F	Histidine kinase
E3Z27_RS01340	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E3Z27_RS01345	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E3Z27_RS01350	ENOG4105VEJ	Heat shock protein
E3Z27_RS01355	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E3Z27_RS01360	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E3Z27_RS01375	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3Z27_RS01395	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E3Z27_RS01400	ENOG4105C5Q	Transcriptional regulator
E3Z27_RS01405	ENOG4109066	lysm domain bon superfamily protein
E3Z27_RS01410	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E3Z27_RS01415	ENOG4107RK2	ADP-ribose diphosphatase NudE
E3Z27_RS01420	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E3Z27_RS01430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS01435	ENOG4105CQZ	Histidine kinase
E3Z27_RS01445	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E3Z27_RS01455	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E3Z27_RS01470	ENOG4105DWY	Agmatine deiminase
E3Z27_RS01485	ENOG4105J5J	Outer membrane porin
E3Z27_RS01530	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS01560	ENOG4105E89	ABC transporter
E3Z27_RS01565	ENOG4108JEH	abc transporter atp-binding protein
E3Z27_RS01580	ENOG4105DFS	Conserved Protein
E3Z27_RS01605	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
E3Z27_RS01625	ENOG4105FCD	Major Facilitator
E3Z27_RS01630	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E3Z27_RS01635	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E3Z27_RS01645	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E3Z27_RS01650	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E3Z27_RS01670	ENOG41063SB	peptidase
E3Z27_RS01675	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E3Z27_RS01685	ENOG4105VW4	glutaredoxin 3
E3Z27_RS01690	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E3Z27_RS01695	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E3Z27_RS01705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS01710	ENOG4105CUX	Signal transduction histidine kinase
E3Z27_RS01735	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
E3Z27_RS01750	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
E3Z27_RS01765	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E3Z27_RS01785	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS01795	ENOG4105QNF	Outer membrane lipoprotein
E3Z27_RS01800	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E3Z27_RS01805	ENOG4105CZE	histidine utilization repressor
E3Z27_RS01810	ENOG41090B9	response to stress
E3Z27_RS01815	ENOG4105CGP	Urocanate hydratase
E3Z27_RS01820	ENOG4105ETS	cytosine purines uracil thiamine allantoin
E3Z27_RS01830	ENOG4108HQS	Glycine betaine
E3Z27_RS01835	ENOG4108IJ7	Glycine betaine
E3Z27_RS01840	ENOG4105C84	Histidine ammonia-lyase
E3Z27_RS01845	ENOG4105C84	Histidine ammonia-lyase
E3Z27_RS01850	ENOG4105CI2	imidazolone-5-propionate hydrolase
E3Z27_RS01860	ENOG4108HGY	Proline imino-peptidase
E3Z27_RS01865	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E3Z27_RS01870	ENOG4105DJ9	glucan biosynthesis protein
E3Z27_RS01875	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
E3Z27_RS01885	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS01890	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS01905	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3Z27_RS01910	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3Z27_RS01915	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
E3Z27_RS01925	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E3Z27_RS01935	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E3Z27_RS01955	ENOG4105U5Y	Transcriptional regulator
E3Z27_RS01980	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
E3Z27_RS01985	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
E3Z27_RS01995	ENOG4105C75	arginyL-tRNA synthetase
E3Z27_RS02005	ENOG4105VFB	Binds the 23S rRNA (By similarity)
E3Z27_RS02015	ENOG4105C6K	Malic enzyme
E3Z27_RS02020	ENOG4108JQC	penicillin-binding protein 1A
E3Z27_RS02045	ENOG4105E4G	Type IV pilus
E3Z27_RS02050	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E3Z27_RS02055	ENOG4105D49	3-dehydroquinate synthase
E3Z27_RS02065	ENOG4105CBC	glutamate synthase
E3Z27_RS02070	ENOG4105BZ8	glutamate synthase
E3Z27_RS02075	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E3Z27_RS02080	ENOG4108M1A	Chitin-binding protein
E3Z27_RS02095	ENOG4107QHF	type ii secretion system protein e
E3Z27_RS02100	ENOG4105D7Q	type ii secretion system
E3Z27_RS02105	ENOG4108VAU	general secretion pathway protein G
E3Z27_RS02110	ENOG4105VWV	general secretion pathway protein h
E3Z27_RS02115	ENOG4105X5Z	General secretion pathway protein I
E3Z27_RS02120	ENOG4108WWZ	General secretion pathway protein J
E3Z27_RS02130	ENOG4108ADH	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
E3Z27_RS02140	ENOG4105D94	Major Facilitator Superfamily
E3Z27_RS02145	ENOG4106NZI	LysR family Transcriptional regulator
E3Z27_RS02150	ENOG4105VUH	addiction module killer protein
E3Z27_RS02155	ENOG4105YES	addiction module antidote protein
E3Z27_RS02170	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3Z27_RS02175	ENOG4105C2D	reductase
E3Z27_RS02185	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3Z27_RS02195	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E3Z27_RS02200	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E3Z27_RS02220	ENOG4105C84	Histidine ammonia-lyase
E3Z27_RS02235	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
E3Z27_RS02250	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E3Z27_RS02265	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E3Z27_RS02270	ENOG4105K63	Thioredoxin
E3Z27_RS02280	ENOG4105CNG	UPF0061 protein
E3Z27_RS02285	ENOG4105EGS	Mechanosensitive ion channel
E3Z27_RS02290	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
E3Z27_RS02310	ENOG41069D7	Methyl-accepting chemotaxis
E3Z27_RS02315	ENOG4105CSU	acyl-Coa dehydrogenase
E3Z27_RS02320	ENOG4105C26	Dehydrogenase
E3Z27_RS02325	ENOG4105CK7	Sodium proline symporter
E3Z27_RS02335	ENOG4105CS6	Rhs element vgr protein
E3Z27_RS02345	ENOG4105D6S	protein involved in catabolism of external DNA
E3Z27_RS02350	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E3Z27_RS02355	ENOG4105BZU	Histidine kinase
E3Z27_RS02365	ENOG4107QSN	dihydrolipoamide acetyltransferase
E3Z27_RS02370	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E3Z27_RS02375	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E3Z27_RS02380	ENOG4105XA0	heptosyltransferase ii
E3Z27_RS02385	ENOG4105D16	lipopolysaccharide heptosyltransferase i
E3Z27_RS02390	ENOG4107RJ7	Glycosyl transferase (Group 1
E3Z27_RS02420	ENOG4107TAE	Glycosyl transferase (Group 1
E3Z27_RS02445	ENOG4108SHN	Glycosyl transferase, family 2
E3Z27_RS02455	ENOG4105BZ1	(ABC) transporter
E3Z27_RS02460	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
E3Z27_RS02465	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E3Z27_RS02490	ENOG4107SET	aldo keto reductase
E3Z27_RS02495	ENOG41087SS	fad dependent oxidoreductase
E3Z27_RS02500	ENOG410814C	multidrug resistance protein
E3Z27_RS02505	ENOG4105EJC	lysr family transcriptional regulator
E3Z27_RS02510	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E3Z27_RS02515	ENOG4105DFG	type I secretion outer membrane protein
E3Z27_RS02520	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E3Z27_RS02535	ENOG41087AY	ADP-Ribose pyrophosphatase
E3Z27_RS02545	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E3Z27_RS02555	ENOG4105IPS	esterase
E3Z27_RS02560	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3Z27_RS02570	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3Z27_RS02585	ENOG4105EAC	phosphoserine phosphatase
E3Z27_RS02595	ENOG4105DJ4	phosphatidylserine decarboxylase
E3Z27_RS02600	ENOG4105KHC	sulfurtransferase
E3Z27_RS02610	ENOG4107RD7	Flagellar Motor Protein, MotA
E3Z27_RS02615	ENOG4105ER2	Ompa motb domain protein
E3Z27_RS02625	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E3Z27_RS02630	ENOG4105EN6	Membrane
E3Z27_RS02635	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E3Z27_RS02640	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E3Z27_RS02645	ENOG4105K8N	protein family UPF0079, ATPase
E3Z27_RS02650	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E3Z27_RS02655	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E3Z27_RS02660	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E3Z27_RS02665	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E3Z27_RS02670	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E3Z27_RS02675	ENOG4107QJR	hflk protein
E3Z27_RS02680	ENOG4105EPW	hflc protein
E3Z27_RS02685	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
E3Z27_RS02690	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E3Z27_RS02695	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS02710	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E3Z27_RS02715	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E3Z27_RS02720	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
E3Z27_RS02735	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E3Z27_RS02745	ENOG4105CCT	upf0313 protein
E3Z27_RS02770	ENOG4105NPQ	Pfam:DUF403
E3Z27_RS02785	ENOG4108URH	decarboxylase
E3Z27_RS02795	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
E3Z27_RS02800	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E3Z27_RS02805	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS02810	ENOG4105C26	Dehydrogenase
E3Z27_RS02815	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS02825	ENOG4105C32	Amino acid ABC transporter (Permease)
E3Z27_RS02830	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E3Z27_RS02835	ENOG4105C0Z	ABC transporter
E3Z27_RS02840	ENOG4108IV0	ABC, transporter
E3Z27_RS02845	ENOG4105EMU	Dehydrogenase
E3Z27_RS02865	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E3Z27_RS02870	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
E3Z27_RS02885	ENOG41066T0	asmA family
E3Z27_RS02900	ENOG4105VIF	phosphate starvation-inducible protein
E3Z27_RS02910	ENOG4105R8A	Heat shock protein
E3Z27_RS02915	ENOG4105DVC	DnaJ domain protein
E3Z27_RS02920	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
E3Z27_RS02930	ENOG4105KI2	Urea amidohydrolase subunit beta
E3Z27_RS02945	ENOG4108YZ9	Urea amidohydrolase subunit gamma
E3Z27_RS02950	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E3Z27_RS02955	ENOG4108IV0	ABC, transporter
E3Z27_RS02960	ENOG4105C0Z	ABC transporter
E3Z27_RS02970	ENOG4105C32	Amino acid ABC transporter (Permease)
E3Z27_RS02975	ENOG41083Z3	extracellular ligand-binding receptor
E3Z27_RS02980	ENOG4105EHG	Permease protein
E3Z27_RS02990	ENOG4105E0A	ABC, transporter
E3Z27_RS03040	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
E3Z27_RS03045	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
E3Z27_RS03055	ENOG41081F0	Precorrin-8x methylmutase
E3Z27_RS03060	ENOG4105DVK	Precorrin-2 c20-methyltransferase
E3Z27_RS03090	ENOG4105BZU	Histidine kinase
E3Z27_RS03095	ENOG4105C12	Phosphoribosylglycinamide synthetase
E3Z27_RS03100	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E3Z27_RS03105	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E3Z27_RS03110	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3Z27_RS03120	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E3Z27_RS03130	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3Z27_RS03135	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E3Z27_RS03140	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E3Z27_RS03150	ENOG4105BZU	Histidine kinase
E3Z27_RS03160	ENOG4105PTV	Nudix Hydrolase
E3Z27_RS03165	ENOG4108ZJT	translation initiation factor, Sui1
E3Z27_RS03170	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E3Z27_RS03175	ENOG4105CS6	Rhs element vgr protein
E3Z27_RS03185	ENOG4107R73	Mate efflux family protein
E3Z27_RS03215	ENOG4106371	Methyltransferase
E3Z27_RS03235	ENOG4105CHR	reductase
E3Z27_RS03245	ENOG4105DHU	Bile acid
E3Z27_RS03250	ENOG4105R1U	AraC Family Transcriptional Regulator
E3Z27_RS03260	ENOG4108Z6Z	Transcriptional regulator
E3Z27_RS03265	ENOG4105C59	p-type ATPase
E3Z27_RS03285	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E3Z27_RS03290	ENOG4105CR8	Transcriptional regulator
E3Z27_RS03300	ENOG41079KZ	Major Facilitator Superfamily
E3Z27_RS03305	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E3Z27_RS03340	ENOG4108R86	Transcriptional regulator
E3Z27_RS03345	ENOG4105EVZ	LysR family transcriptional regulator
E3Z27_RS03355	ENOG4105C26	Dehydrogenase
E3Z27_RS03385	ENOG4105DSY	exodeoxyribonuclease V, gamma
E3Z27_RS03390	ENOG4107QKA	exodeoxyribonuclease V beta
E3Z27_RS03395	ENOG4107QYX	exodeoxyribonuclease v alpha
E3Z27_RS03405	ENOG4105BZU	Histidine kinase
E3Z27_RS03420	ENOG4105C26	Dehydrogenase
E3Z27_RS03425	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E3Z27_RS03450	ENOG4105C9B	Cysteine desulfurase
E3Z27_RS03465	ENOG4106NZI	LysR family Transcriptional regulator
E3Z27_RS03480	ENOG4105NF4	modulator of drug activity
E3Z27_RS03495	ENOG4105CHH	sulfate transporter
E3Z27_RS03540	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS03595	ENOG4105E1F	short-chain dehydrogenase reductase
E3Z27_RS03600	ENOG4105CF7	AraC family transcriptional regulator
E3Z27_RS03620	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E3Z27_RS03630	ENOG4108F5E	vimentin
E3Z27_RS03645	ENOG4108I5C	dEAD DEAH box helicase
E3Z27_RS03670	ENOG4105DFP	Integrase
E3Z27_RS03690	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
E3Z27_RS03700	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E3Z27_RS03705	ENOG4105DAA	L-lactate
E3Z27_RS03710	ENOG41073TP	transcriptional regulator
E3Z27_RS03715	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E3Z27_RS03720	ENOG4105C8J	)-transporter
E3Z27_RS03725	ENOG4108Z1B	Cyclase dehydrase
E3Z27_RS03730	ENOG4105VDB	UPF0125 protein
E3Z27_RS03735	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3Z27_RS03740	ENOG41090R7	Ferric uptake
E3Z27_RS03745	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E3Z27_RS03750	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E3Z27_RS03755	ENOG4105CFG	Acts as a chaperone (By similarity)
E3Z27_RS03760	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E3Z27_RS03765	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E3Z27_RS03770	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E3Z27_RS03775	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E3Z27_RS03780	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E3Z27_RS03790	ENOG4105HBR	Rna-binding protein
E3Z27_RS03795	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E3Z27_RS03800	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E3Z27_RS03805	ENOG4105EEI	dihydropteroate synthase
E3Z27_RS03815	ENOG4105CP7	Triose-phosphate isomerase
E3Z27_RS03820	ENOG4105NTZ	Preprotein translocase subunit SecG
E3Z27_RS03840	ENOG4105CHV	Transcription elongation factor NusA
E3Z27_RS03850	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E3Z27_RS03855	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E3Z27_RS03860	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E3Z27_RS03865	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E3Z27_RS03885	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E3Z27_RS03895	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E3Z27_RS03905	ENOG4108NVR	Methyl-accepting chemotaxis
E3Z27_RS03910	ENOG4105EYA	deoxyribonuclease
E3Z27_RS03915	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
E3Z27_RS03920	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E3Z27_RS03925	ENOG4105DE4	1-phosphofructokinase
E3Z27_RS03930	ENOG4105DM4	PTS System
E3Z27_RS03940	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E3Z27_RS03945	ENOG4108ESX	Receptor
E3Z27_RS03950	ENOG4107E2E	PKHD-type hydroxylase
E3Z27_RS03960	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3Z27_RS03965	ENOG4108IJ8	ABC transporter
E3Z27_RS03970	ENOG4105E90	ABC transporter
E3Z27_RS03975	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
E3Z27_RS03980	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
E3Z27_RS03985	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E3Z27_RS03995	ENOG4108JQ7	(ABC) transporter
E3Z27_RS04000	ENOG4105C3U	ABC transporter
E3Z27_RS04005	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS04010	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS04015	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3Z27_RS04020	ENOG4105J5J	Outer membrane porin
E3Z27_RS04025	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3Z27_RS04030	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3Z27_RS04035	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3Z27_RS04050	ENOG4105TX3	Histidine kinase
E3Z27_RS04060	ENOG4105CQ0	ABC transporter
E3Z27_RS04075	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
E3Z27_RS04085	ENOG4105DJB	Major Facilitator Superfamily
E3Z27_RS04090	ENOG4105CTX	dehydratase
E3Z27_RS04100	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E3Z27_RS04115	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E3Z27_RS04120	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E3Z27_RS04125	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E3Z27_RS04130	ENOG4105DFF	Rod shape-determining protein mreb
E3Z27_RS04135	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E3Z27_RS04145	ENOG4108Z03	MAF-like protein
E3Z27_RS04150	ENOG4105C03	ribonuclease
E3Z27_RS04165	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
E3Z27_RS04170	ENOG4105N42	UPF0307 protein
E3Z27_RS04175	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E3Z27_RS04185	ENOG4105C9Q	fumarate hydratase class II
E3Z27_RS04195	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3Z27_RS04210	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E3Z27_RS04215	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
E3Z27_RS04220	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
E3Z27_RS04225	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3Z27_RS04230	ENOG4108IUZ	ABC transporter
E3Z27_RS04235	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E3Z27_RS04245	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E3Z27_RS04250	ENOG4105C2X	Arabinose 5-phosphate isomerase
E3Z27_RS04255	ENOG4105DHJ	ABC, transporter
E3Z27_RS04260	ENOG4105CY3	ABC transporter, permease
E3Z27_RS04265	ENOG4107PE3	Mammalian cell entry related domain protein
E3Z27_RS04280	ENOG4105VFK	BolA family
E3Z27_RS04285	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E3Z27_RS04290	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E3Z27_RS04295	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E3Z27_RS04300	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E3Z27_RS04315	ENOG4105C0H	protease
E3Z27_RS04320	ENOG4107QNR	UPF0135 protein
E3Z27_RS04325	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E3Z27_RS04335	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E3Z27_RS04340	ENOG4106HNH	Acyl-transferase
E3Z27_RS04345	ENOG4105C6K	Malic enzyme
E3Z27_RS04355	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E3Z27_RS04360	ENOG4108V06	Glutathione peroxidase
E3Z27_RS04375	ENOG4105EXN	Sulfate transport protein CysZ
E3Z27_RS04380	ENOG4105C3M	thioredoxin reductase
E3Z27_RS04385	ENOG4108JPW	Aminotransferase
E3Z27_RS04400	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
E3Z27_RS04405	ENOG4105EUJ	GTP cyclohydrolase i
E3Z27_RS04410	ENOG410642E	Short chain dehydrogenase
E3Z27_RS04425	ENOG4105BZU	Histidine kinase
E3Z27_RS04430	ENOG4105QDK	Flavodoxin
E3Z27_RS04435	ENOG4105MP9	class II Aldolase
E3Z27_RS04440	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
E3Z27_RS04445	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
E3Z27_RS04460	ENOG4105D25	secreted protein
E3Z27_RS04480	ENOG4105F1J	Homogentisate 1,2-dioxygenase
E3Z27_RS04485	ENOG4105ERH	Fumarylacetoacetate hydrolase
E3Z27_RS04490	ENOG4108RXX	maleylacetoacetate isomerase
E3Z27_RS04495	ENOG41063JG	Transcriptional regulator
E3Z27_RS04505	ENOG4105DKK	Benzoate
E3Z27_RS04540	ENOG4108Q5Y	Membrane
E3Z27_RS04545	ENOG4105C5I	Dehydrogenase
E3Z27_RS04570	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E3Z27_RS04575	ENOG4105RXK	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E3Z27_RS04580	ENOG4105E2S	oxidase) subunit II
E3Z27_RS04585	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E3Z27_RS04590	ENOG4105CCU	oxidase (Subunit III)
E3Z27_RS04595	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E3Z27_RS04600	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E3Z27_RS04615	ENOG4105HEI	LysR family (Transcriptional regulator
E3Z27_RS04620	ENOG4105C8Y	Acetylornithine aminotransferase
E3Z27_RS04625	ENOG4105UYK	outer membrane protein a
E3Z27_RS04635	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E3Z27_RS04650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E3Z27_RS04655	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
E3Z27_RS04660	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E3Z27_RS04665	ENOG4105KWG	Pfam:DUF1696
E3Z27_RS04685	ENOG4108MA7	Inherit from COG: YD repeat protein
E3Z27_RS04745	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3Z27_RS04750	ENOG4105BZU	Histidine kinase
E3Z27_RS04760	ENOG4105BZU	Histidine kinase
E3Z27_RS04790	ENOG4105M1T	rho-binding antiterminator
E3Z27_RS04795	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3Z27_RS04800	ENOG4108S8N	class II Aldolase
E3Z27_RS04830	ENOG4105EGI	Transcriptional regulator
E3Z27_RS04870	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E3Z27_RS04875	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E3Z27_RS04880	ENOG4105VIE	preprotein translocase, subunit YajC
E3Z27_RS04885	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3Z27_RS04890	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3Z27_RS04895	ENOG4107MBR	17 kDa surface antigen
E3Z27_RS04900	ENOG4105ECY	inositol monophosphatase
E3Z27_RS04910	ENOG4105D7W	serine acetyltransferase
E3Z27_RS04915	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E3Z27_RS04920	ENOG4105C3J	Cysteine desulfurase
E3Z27_RS04930	ENOG4108Z4V	iron-sulfur cluster assembly
E3Z27_RS04935	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
E3Z27_RS04940	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
E3Z27_RS04945	ENOG4108ZIT	Ferredoxin, 2FE-2S
E3Z27_RS04950	ENOG4105WVQ	Fe-S assembly protein IscX
E3Z27_RS04955	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E3Z27_RS04960	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E3Z27_RS04975	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E3Z27_RS04980	ENOG4105CUT	histidyl-tRNA synthetase
E3Z27_RS04990	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3Z27_RS04995	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E3Z27_RS05000	ENOG4105CHM	Aminotransferase
E3Z27_RS05015	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E3Z27_RS05020	ENOG4105DR5	peptidase
E3Z27_RS05025	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E3Z27_RS05040	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3Z27_RS05045	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3Z27_RS05050	ENOG4105CC0	LysR family Transcriptional regulator
E3Z27_RS05065	ENOG4108JGH	Tetr family transcriptional regulator
E3Z27_RS05070	ENOG4105CAY	ferredoxin--nadp reductase
E3Z27_RS05080	ENOG4107414	GntR family transcriptional regulator
E3Z27_RS05085	ENOG4105C5Y	PTS System
E3Z27_RS05090	ENOG4105CG3	alpha amylase, catalytic region
E3Z27_RS05095	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
E3Z27_RS05100	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E3Z27_RS05145	ENOG4108Z6B	deaminase
E3Z27_RS05150	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
E3Z27_RS05155	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E3Z27_RS05160	ENOG4108NC2	Outer membrane protease
E3Z27_RS05170	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E3Z27_RS05175	ENOG4105CSH	Transporter
E3Z27_RS05180	ENOG4108JU6	CBS domain protein
E3Z27_RS05190	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3Z27_RS05195	ENOG4105K5M	30s ribosomal protein S16
E3Z27_RS05200	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E3Z27_RS05205	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E3Z27_RS05210	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E3Z27_RS05220	ENOG4105T95	Thiol disulfide interChange protein
E3Z27_RS05225	ENOG4105D6E	homoserine dehydrogenase
E3Z27_RS05230	ENOG4105D98	threonine synthase
E3Z27_RS05235	ENOG4105BZU	Histidine kinase
E3Z27_RS05250	ENOG4108VWS	Yaeq family
E3Z27_RS05255	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E3Z27_RS05260	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3Z27_RS05265	ENOG4105DJ9	glucan biosynthesis protein
E3Z27_RS05285	ENOG4105C26	Dehydrogenase
E3Z27_RS05290	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS05295	ENOG4105D81	ABC transporter, permease
E3Z27_RS05300	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS05305	ENOG4107TYH	extracellular solute-binding protein family 1
E3Z27_RS05315	ENOG4107RSM	transcriptional regulator
E3Z27_RS05335	ENOG4108KTQ	Methyltransferase
E3Z27_RS05350	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E3Z27_RS05365	ENOG4105CRK	lysyL-tRNA synthetase
E3Z27_RS05385	ENOG4107XM9	(LipO)protein
E3Z27_RS05395	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E3Z27_RS05410	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E3Z27_RS05415	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E3Z27_RS05420	ENOG41072GX	Peptidase M22 Glycoprotease
E3Z27_RS05430	ENOG41081XQ	Conserved Protein
E3Z27_RS05435	ENOG4105CR4	methylisocitrate lyase
E3Z27_RS05450	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
E3Z27_RS05460	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E3Z27_RS05475	ENOG4108MNP	Glycoprotein polysaccharide metabolism
E3Z27_RS05480	ENOG4105E55	glycerol-3-phosphate acyltransferase
E3Z27_RS05485	ENOG4105VEQ	Cold shock protein
E3Z27_RS05495	ENOG4105DHI	Methyltransferase
E3Z27_RS05500	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E3Z27_RS05505	ENOG4105CUZ	uba thif-type nad fad binding protein
E3Z27_RS05510	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E3Z27_RS05515	ENOG4105C9B	Cysteine desulfurase
E3Z27_RS05520	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
E3Z27_RS05525	ENOG4105KUZ	arsenate reductase
E3Z27_RS05530	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E3Z27_RS05545	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
E3Z27_RS05550	ENOG4105CHM	Aminotransferase
E3Z27_RS05555	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E3Z27_RS05560	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E3Z27_RS05570	ENOG4105CE9	30S ribosomal protein S2
E3Z27_RS05575	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E3Z27_RS05580	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E3Z27_RS05590	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E3Z27_RS05595	ENOG4105KNE	Phosphatidate cytidylyltransferase
E3Z27_RS05600	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E3Z27_RS05605	ENOG4105DZP	Membrane-associated zinc metalloprotease
E3Z27_RS05610	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3Z27_RS05615	ENOG4105X4K	outer membrane chaperone skp
E3Z27_RS05620	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3Z27_RS05625	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E3Z27_RS05630	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3Z27_RS05635	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3Z27_RS05640	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3Z27_RS05645	ENOG4105C0B	DNA polymerase III (alpha subunit)
E3Z27_RS05650	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E3Z27_RS05655	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E3Z27_RS05665	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E3Z27_RS05670	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E3Z27_RS05675	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E3Z27_RS05680	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E3Z27_RS05685	ENOG4105EXG	Transcriptional regulator
E3Z27_RS05695	ENOG4105C4W	S-formylglutathione hydrolase
E3Z27_RS05700	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E3Z27_RS05705	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
E3Z27_RS05710	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E3Z27_RS05715	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E3Z27_RS05720	ENOG4108K5P	(LipO)protein
E3Z27_RS05725	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3Z27_RS05730	ENOG4108Z4U	Ferredoxin
E3Z27_RS05735	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E3Z27_RS05745	ENOG4108XTP	Transcriptional regulator
E3Z27_RS05855	ENOG4105TKZ	Tail Sheath
E3Z27_RS05895	ENOG4105WR6	Phage protein, GP46
E3Z27_RS05920	ENOG4105NVB	glycoside hydrolase, family 19
E3Z27_RS05930	ENOG4107TH8	cina domain protein
E3Z27_RS05935	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E3Z27_RS05940	ENOG4105Y3E	Modulates RecA activity (By similarity)
E3Z27_RS05960	ENOG4106IUH	DTW domain containing protein
E3Z27_RS05970	ENOG41080IJ	Diacylglycerol kinase
E3Z27_RS05975	ENOG4105DUM	transcriptional regulator, lysR family
E3Z27_RS05980	ENOG4105DP0	ferredoxin-NADP reductase
E3Z27_RS05985	ENOG4108R96	Methyltransferase, YaeB family
E3Z27_RS05990	ENOG4108W15	Protein of unknown function (DUF1456)
E3Z27_RS05995	ENOG4105FE9	pseudouridine synthase
E3Z27_RS06000	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3Z27_RS06005	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E3Z27_RS06010	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E3Z27_RS06020	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3Z27_RS06035	ENOG4105FF5	Membrane
E3Z27_RS06050	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E3Z27_RS06060	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E3Z27_RS06085	ENOG4105DHP	deoxycytidine triphosphate deaminase
E3Z27_RS06100	ENOG4107QRT	dEAD DEAH box helicase
E3Z27_RS06105	ENOG4108JEH	abc transporter atp-binding protein
E3Z27_RS06115	ENOG4106YG3	ABC transporter
E3Z27_RS06120	ENOG4105DSP	amino acid AbC transporter
E3Z27_RS06125	ENOG4105E89	ABC transporter
E3Z27_RS06130	ENOG4107T0X	DNA ligase
E3Z27_RS06145	ENOG4105CYM	Glutathione S-transferase
E3Z27_RS06155	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E3Z27_RS06165	ENOG4105K5B	UPF0225 protein
E3Z27_RS06175	ENOG4105CDV	Ompa motb domain protein
E3Z27_RS06195	ENOG4105DVT	helicase
E3Z27_RS06205	ENOG4108ZG0	Ompa motb domain protein
E3Z27_RS06210	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
E3Z27_RS06225	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3Z27_RS06235	ENOG4105DZ0	fad dependent oxidoreductase
E3Z27_RS06250	ENOG4105HEI	LysR family (Transcriptional regulator
E3Z27_RS06265	ENOG4105E18	UPF0276 protein
E3Z27_RS06275	ENOG4108IV0	ABC, transporter
E3Z27_RS06280	ENOG4105C0Z	ABC transporter
E3Z27_RS06285	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E3Z27_RS06290	ENOG4105C32	Amino acid ABC transporter (Permease)
E3Z27_RS06295	ENOG4105CP9	extracellular ligand-binding receptor
E3Z27_RS06315	ENOG4108I5G	Major Facilitator superfamily
E3Z27_RS06340	ENOG4105C5B	carbamate kinase
E3Z27_RS06345	ENOG4105DBV	ornithine carbamoyltransferase
E3Z27_RS06350	ENOG4105CEU	Arginine dihydrolase
E3Z27_RS06355	ENOG4105D5Q	Arginine ornithine antiporter
E3Z27_RS06360	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
E3Z27_RS06365	ENOG4105WD1	Membrane
E3Z27_RS06370	ENOG4108YNN	Heme oxygenase
E3Z27_RS06380	ENOG4108S3W	Anti-feci sigma factor, fecr
E3Z27_RS06390	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3Z27_RS06395	ENOG4105C01	Dihydroxy-acid dehydratase
E3Z27_RS06405	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3Z27_RS06410	ENOG4105E0F	Histidine kinase
E3Z27_RS06415	ENOG4107QKS	N-acylglucosamine 2-epimerase
E3Z27_RS06420	ENOG4108JP0	extracellular solute-binding protein family 1
E3Z27_RS06425	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS06430	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS06435	ENOG4108IJ9	(ABC) transporter
E3Z27_RS06440	ENOG4105TW1	Carbohydrate-selective porin OprB
E3Z27_RS06445	ENOG4105DSB	aldose 1-epimerase
E3Z27_RS06450	ENOG4106KNT	transcriptional regulator
E3Z27_RS06455	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E3Z27_RS06465	ENOG4108UHU	Aldolase
E3Z27_RS06470	ENOG4107STF	Involved in phosphonate degradation (By similarity)
E3Z27_RS06475	ENOG4105VRT	cytoplasmic protein
E3Z27_RS06495	ENOG4105Y49	secretion protein, HlyD family
E3Z27_RS06500	ENOG4108F01	MaoC domain protein
E3Z27_RS06505	ENOG4105E5G	Alpha beta hydrolase fold
E3Z27_RS06510	ENOG4105CEY	Amp-dependent synthetase and ligase
E3Z27_RS06525	ENOG4107U9T	Pfam:Ribonuclease_BN
E3Z27_RS06530	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3Z27_RS06545	ENOG4105DIQ	Transcriptional regulator
E3Z27_RS06550	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E3Z27_RS06555	ENOG4105C6Z	Gluconate
E3Z27_RS06560	ENOG4105CHM	Aminotransferase
E3Z27_RS06585	ENOG4105GRZ	Ycii-related protein
E3Z27_RS06595	ENOG4105CHP	RNA polymerase
E3Z27_RS06605	ENOG4105BZU	Histidine kinase
E3Z27_RS06610	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3Z27_RS06615	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
E3Z27_RS06625	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E3Z27_RS06630	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E3Z27_RS06640	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E3Z27_RS06650	ENOG4105CJ3	phosphate transporter
E3Z27_RS06660	ENOG4107HP6	Transcriptional regulator
E3Z27_RS06665	ENOG4105D2S	major facilitator superfamily
E3Z27_RS06680	ENOG4105CHU	acetyl-coa acetyltransferase
E3Z27_RS06695	ENOG4105CSH	Transporter
E3Z27_RS06700	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E3Z27_RS06705	ENOG4105F2Z	3-oxoadipate enol-lactonase
E3Z27_RS06710	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E3Z27_RS06725	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3Z27_RS06730	ENOG4105BZS	acriflavin resistance protein
E3Z27_RS06735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E3Z27_RS06750	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3Z27_RS06755	ENOG4105F27	Major Facilitator
E3Z27_RS06795	ENOG4105DZQ	phospholipase D Transphosphatidylase
E3Z27_RS06800	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
E3Z27_RS06805	ENOG4108V0P	LemA family
E3Z27_RS06810	ENOG4105HA9	of methanol dehydrogenase type
E3Z27_RS06825	ENOG4107R7Y	intracellular protease Pfpi family
E3Z27_RS06840	ENOG4105C0A	alcohol dehydrogenase
E3Z27_RS06855	ENOG4105BZU	Histidine kinase
E3Z27_RS06865	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3Z27_RS06885	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3Z27_RS06890	ENOG4105EW9	transcriptional regulator AsnC family
E3Z27_RS06900	ENOG4105CHR	reductase
E3Z27_RS06915	ENOG4105I08	Pseudouridine synthase
E3Z27_RS06925	ENOG4105BZU	Histidine kinase
E3Z27_RS06935	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E3Z27_RS06940	ENOG4108KK1	membrane protein AbrB duplication
E3Z27_RS06965	ENOG4105DHQ	Histidine kinase
E3Z27_RS06975	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E3Z27_RS06980	ENOG4105Y75	tpr repeat protein
E3Z27_RS06990	ENOG4108IYU	L-aspartate oxidase
E3Z27_RS06995	ENOG4105EMN	RNA polymerase sigma factor
E3Z27_RS07000	ENOG41069E1	anti sigma-E protein RseA
E3Z27_RS07005	ENOG4105VQK	sigma E regulatory protein, MucB RseB
E3Z27_RS07010	ENOG4105C0H	protease
E3Z27_RS07020	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E3Z27_RS07030	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3Z27_RS07040	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3Z27_RS07045	ENOG4105GJM	(LipO)protein
E3Z27_RS07050	ENOG4105Q2H	domain protein
E3Z27_RS07055	ENOG4105C8V	SAICAR synthetase
E3Z27_RS07070	ENOG4108NVR	Methyl-accepting chemotaxis
E3Z27_RS07080	ENOG41082W1	Cupin 2, conserved barrel domain protein
E3Z27_RS07085	ENOG4107EPN	Domain of unknown function (DUF1508)
E3Z27_RS07105	ENOG4105CFQ	glutamine synthetase
E3Z27_RS07110	ENOG4105DIJ	Phosphoethanolamine transferase
E3Z27_RS07125	ENOG4105VNG	YcgL domain-containing protein
E3Z27_RS07135	ENOG4108ZZ3	UPF0260 protein
E3Z27_RS07155	ENOG4105N1F	Hnh endonuclease
E3Z27_RS07185	ENOG4105E7A	Glutamine amidotransferase
E3Z27_RS07195	ENOG4107RGD	Major Facilitator superfamily
E3Z27_RS07200	ENOG4105E7W	lamb ycsf family protein
E3Z27_RS07205	ENOG4105P4J	Allophanate hydrolase, subunit 1
E3Z27_RS07220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3Z27_RS07250	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
E3Z27_RS07255	ENOG4105CQ7	ATP-dependent helicase
E3Z27_RS07285	ENOG4105BZ1	(ABC) transporter
E3Z27_RS07290	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E3Z27_RS07295	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E3Z27_RS07310	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E3Z27_RS07315	ENOG4105BZU	Histidine kinase
E3Z27_RS07320	ENOG4105EMK	carboxylate amino acid amine transporter
E3Z27_RS07325	ENOG4105CR8	Transcriptional regulator
E3Z27_RS07330	ENOG4105CHJ	isochorismatase hydrolase
E3Z27_RS07375	ENOG4105C4R	Atp-dependent dna helicase
E3Z27_RS07380	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E3Z27_RS07480	ENOG4107RRE	RNA-directed DNA polymerase
E3Z27_RS07500	ENOG4105C1J	atp-dependent rna helicase
E3Z27_RS07510	ENOG4105D5K	Hemolysin activator protein
E3Z27_RS07570	ENOG4105QNR	S1 RNA binding domain protein
E3Z27_RS07575	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
E3Z27_RS07585	ENOG4105EGI	Transcriptional regulator
E3Z27_RS07605	ENOG4105CYW	agmatinase
E3Z27_RS07610	ENOG4105EVZ	LysR family transcriptional regulator
E3Z27_RS07650	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E3Z27_RS07655	ENOG4105WD1	Membrane
E3Z27_RS07665	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E3Z27_RS07680	ENOG4105D78	K07001 NTE family protein
E3Z27_RS07715	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E3Z27_RS07725	ENOG4105CGF	Aromatic amino acid aminotransferase
E3Z27_RS07730	ENOG41090A4	Pterin carbinolamine dehydratase
E3Z27_RS07735	ENOG4105MIR	Phenylalanine 4-monooxygenase
E3Z27_RS07740	ENOG4108JU8	Transcriptional regulator
E3Z27_RS07780	ENOG4105CGA	flagellar basal-body rod protein FlgG
E3Z27_RS07785	ENOG4105CGA	flagellar basal-body rod protein FlgG
E3Z27_RS07790	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E3Z27_RS07795	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
E3Z27_RS07800	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
E3Z27_RS07805	ENOG4105E1Q	flagellar hook-associated protein
E3Z27_RS07815	ENOG4107RGC	Glycosyl transferase, family 2
E3Z27_RS07825	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E3Z27_RS07830	ENOG4105I03	Flagellin
E3Z27_RS07835	ENOG41063QE	flagellar protein FlaG
E3Z27_RS07840	ENOG4105DTS	flagellar hook-associated
E3Z27_RS07845	ENOG4105MQ3	flagellar protein FliS
E3Z27_RS07855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS07870	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
E3Z27_RS07875	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
E3Z27_RS07890	ENOG4108JIR	Flagellum-specific ATP synthase
E3Z27_RS07905	ENOG4108KXV	response regulator
E3Z27_RS07925	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
E3Z27_RS07930	ENOG4105DD5	Flagellar motor switch protein
E3Z27_RS07935	ENOG4105VTB	flagellar biosynthesis protein fliO
E3Z27_RS07940	ENOG4105CN7	Flagellar biosynthetic protein FliP
E3Z27_RS07945	ENOG4105VS8	Flagellar biosynthetic protein fliq
E3Z27_RS07950	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
E3Z27_RS07955	ENOG4105D00	flagellar biosynthetic protein flhB
E3Z27_RS07960	ENOG4105D7B	Flagellar biosynthesis protein flha
E3Z27_RS07965	ENOG4105FZW	flagellar biosynthesis regulator FlhF
E3Z27_RS07975	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3Z27_RS07980	ENOG4108VYJ	response regulator receiver protein
E3Z27_RS07985	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
E3Z27_RS07990	ENOG4105CBS	Chea signal transduction histidine kinase
E3Z27_RS07995	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E3Z27_RS08000	ENOG4105E14	MotA TolQ exbB proton channel
E3Z27_RS08005	ENOG4106VK6	Flagellar motor protein
E3Z27_RS08010	ENOG4107QJE	Chromosome Partitioning Protein
E3Z27_RS08020	ENOG4108V3W	Chemotaxis protein, CheW
E3Z27_RS08055	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS08060	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
E3Z27_RS08065	ENOG41060IM	Heme exporter protein
E3Z27_RS08075	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E3Z27_RS08080	ENOG4105DA4	cytochrome c-type biogenesis protein
E3Z27_RS08095	ENOG4108M1T	Cytochrome c-type biogenesis protein
E3Z27_RS08105	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
E3Z27_RS08110	ENOG4105E0M	Sulfatase
E3Z27_RS08125	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
E3Z27_RS08130	ENOG4106851	UPF0270 protein
E3Z27_RS08135	ENOG4105DER	m42 family
E3Z27_RS08140	ENOG4107RRY	Cyanophycin synthetase
E3Z27_RS08145	ENOG4105CAQ	asparagine synthetase
E3Z27_RS08150	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
E3Z27_RS08155	ENOG4105CSR	polyphosphate kinase 2
E3Z27_RS08160	ENOG4105CHU	acetyl-coa acetyltransferase
E3Z27_RS08170	ENOG4105QYV	Membrane
E3Z27_RS08175	ENOG4105C9Q	fumarate hydratase class II
E3Z27_RS08185	ENOG4105M85	Bola protein
E3Z27_RS08190	ENOG4105C72	UPF0176 protein
E3Z27_RS08200	ENOG4105BZ1	(ABC) transporter
E3Z27_RS08205	ENOG4105BZU	Histidine kinase
E3Z27_RS08215	ENOG4105BZU	Histidine kinase
E3Z27_RS08220	ENOG4105UBK	short-chain dehydrogenase reductase
E3Z27_RS08225	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3Z27_RS08230	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E3Z27_RS08235	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E3Z27_RS08240	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
E3Z27_RS08245	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3Z27_RS08250	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E3Z27_RS08255	ENOG4105CQC	Prephenate dehydratase
E3Z27_RS08260	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E3Z27_RS08265	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E3Z27_RS08270	ENOG4105CAT	Cytidine monophosphate kinase
E3Z27_RS08275	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E3Z27_RS08285	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3Z27_RS08315	ENOG4105EY8	ABC transporter
E3Z27_RS08335	ENOG4108S0S	Nucleotidyl transferase
E3Z27_RS08345	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E3Z27_RS08350	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
E3Z27_RS08355	ENOG4105D2T	synthase
E3Z27_RS08360	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3Z27_RS08365	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
E3Z27_RS08375	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E3Z27_RS08385	ENOG4105F0R	Cytidylyltransferase
E3Z27_RS08400	ENOG4105EQK	-acetyltransferase
E3Z27_RS08415	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
E3Z27_RS08430	ENOG4105ESV	Glycosyl transferase, family 4
E3Z27_RS08440	ENOG4105KQC	Competence protein
E3Z27_RS08465	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3Z27_RS08470	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3Z27_RS08475	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E3Z27_RS08480	ENOG4105C08	Histidine kinase
E3Z27_RS08520	ENOG4105F8V	Hydrolase, tatD family
E3Z27_RS08525	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3Z27_RS08530	ENOG4108VGI	doxx family
E3Z27_RS08545	ENOG4108RRZ	Transcription elongation factor GreB
E3Z27_RS08550	ENOG4105CV6	ABC transporter, permease
E3Z27_RS08555	ENOG4108I0Y	(ABC) transporter
E3Z27_RS08560	ENOG4108UJV	acyl-CoA thioesterase i
E3Z27_RS08570	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E3Z27_RS08585	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3Z27_RS08590	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E3Z27_RS08605	ENOG4107R11	Transcriptional regulator
E3Z27_RS08610	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E3Z27_RS08625	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E3Z27_RS08635	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E3Z27_RS08640	ENOG4105K56	Transcriptional regulator
E3Z27_RS08660	ENOG4105T0Z	Conserved Protein
E3Z27_RS08665	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
E3Z27_RS08680	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E3Z27_RS08685	ENOG4105FQ6	thiopurine methyltransferase
E3Z27_RS08690	ENOG4105D0M	Protease HtpX homolog
E3Z27_RS08700	ENOG4105E0X	reductase
E3Z27_RS08705	ENOG4108V06	Glutathione peroxidase
E3Z27_RS08710	ENOG4105K56	Transcriptional regulator
E3Z27_RS08715	ENOG4105BZU	Histidine kinase
E3Z27_RS08730	ENOG4108ESY	Metal dependent phosphohydrolase
E3Z27_RS08730	ENOG4108ESY	Metal dependent phosphohydrolase
E3Z27_RS08735	ENOG4105BZU	Histidine kinase
E3Z27_RS08740	ENOG4108WQH	regulatoR
E3Z27_RS08785	ENOG4105D3G	Pseudouridine synthase
E3Z27_RS08795	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E3Z27_RS08800	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E3Z27_RS08805	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3Z27_RS08815	ENOG4107TE5	Lipid kinase
E3Z27_RS08820	ENOG4105WH1	Two component transcriptional regulator luxr family
E3Z27_RS08825	ENOG4105BZU	Histidine kinase
E3Z27_RS08840	ENOG4105QVC	MOSC domain-containing protein
E3Z27_RS08845	ENOG4105NBK	UPF0345 protein
E3Z27_RS08870	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E3Z27_RS08875	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E3Z27_RS08880	ENOG4107ZT5	Thiol disulfide interchange protein
E3Z27_RS08890	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3Z27_RS08895	ENOG4105DHQ	Histidine kinase
E3Z27_RS08905	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E3Z27_RS08920	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E3Z27_RS08945	ENOG4105CDV	Ompa motb domain protein
E3Z27_RS08960	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
E3Z27_RS08965	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E3Z27_RS08990	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E3Z27_RS08995	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
E3Z27_RS09005	ENOG4105BZU	Histidine kinase
E3Z27_RS09010	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
E3Z27_RS09015	ENOG41090ED	Protein with unknown function (DUF469)
E3Z27_RS09020	ENOG4105DKK	Benzoate
E3Z27_RS09025	ENOG4107XBN	GntR Family Transcriptional Regulator
E3Z27_RS09030	ENOG4107QUY	Guanine deaminase
E3Z27_RS09055	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E3Z27_RS09060	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
E3Z27_RS09065	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E3Z27_RS09090	ENOG4105BZU	Histidine kinase
E3Z27_RS09100	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E3Z27_RS09105	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
E3Z27_RS09110	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E3Z27_RS09115	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E3Z27_RS09120	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E3Z27_RS09130	ENOG4105D4P	Coproporphyrinogen iii oxidase
E3Z27_RS09165	ENOG4107TV1	YD repeat protein
E3Z27_RS09180	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
E3Z27_RS09195	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E3Z27_RS09215	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
E3Z27_RS09225	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
E3Z27_RS09235	ENOG4107QM5	aconitate hydratase
E3Z27_RS09240	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
E3Z27_RS09245	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E3Z27_RS09250	ENOG4107QI1	Mate efflux family protein
E3Z27_RS09255	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
E3Z27_RS09265	ENOG4105BZ1	(ABC) transporter
E3Z27_RS09270	ENOG4107R3N	Filamentation induced by cAMP protein fic
E3Z27_RS09275	ENOG4107SC1	transglycosylase
E3Z27_RS09280	ENOG4105C5H	ABC transporter
E3Z27_RS09285	ENOG41081QV	Universal stress protein
E3Z27_RS09295	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3Z27_RS09300	ENOG4105CHU	acetyl-coa acetyltransferase
E3Z27_RS09310	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3Z27_RS09325	ENOG4106AIJ	Cell Division
E3Z27_RS09345	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
E3Z27_RS09350	ENOG4105C0D	helicase
E3Z27_RS09360	ENOG4108JA2	transcriptioN-repair coupling factor
E3Z27_RS09375	ENOG4105CJ2	(LipO)protein
E3Z27_RS09385	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E3Z27_RS09395	ENOG4105D60	lipoprotein releasing system transmembrane protein
E3Z27_RS09400	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3Z27_RS09405	ENOG4105D60	lipoprotein releasing system transmembrane protein
E3Z27_RS09425	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
E3Z27_RS09445	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS09455	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E3Z27_RS09460	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3Z27_RS09470	ENOG4108R1E	Serine threonine protein phosphatase 1
E3Z27_RS09480	ENOG4105MZU	cell filamentation protein
E3Z27_RS09500	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E3Z27_RS09505	ENOG4105HEI	LysR family (Transcriptional regulator
E3Z27_RS09530	ENOG4108K3Z	AraC family transcriptional regulator
E3Z27_RS09560	ENOG4105CK2	sodium dicarboxylate symporter
E3Z27_RS09580	ENOG4105D64	Mechanosensitive ion channel
E3Z27_RS09605	ENOG4105BZU	Histidine kinase
E3Z27_RS09610	ENOG4105CGK	Exodeoxyribonuclease III
E3Z27_RS09630	ENOG4105F9E	Shikimate 5-dehydrogenase
E3Z27_RS09635	ENOG4108YXG	UPF0502 protein
E3Z27_RS09650	ENOG4108SUT	Major Facilitator Superfamily
E3Z27_RS09655	ENOG41063Z6	transcriptional regulator, lysR family
E3Z27_RS09665	ENOG4105EE5	Membrane protein terC
E3Z27_RS09680	ENOG41061WM	D-Alanyl-D-Alanine
E3Z27_RS09685	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E3Z27_RS09705	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E3Z27_RS09710	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E3Z27_RS09715	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E3Z27_RS09720	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E3Z27_RS09725	ENOG4105K70	DNA-binding protein
E3Z27_RS09730	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E3Z27_RS09740	ENOG4108ZX5	transcriptional regulator
E3Z27_RS09755	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3Z27_RS09765	ENOG4108VKM	cytochrome b561
E3Z27_RS09785	ENOG4105CY5	solute-binding protein
E3Z27_RS09805	ENOG4105D38	putrescine abc transporter
E3Z27_RS09810	ENOG4105F38	ABC transporter, permease
E3Z27_RS09815	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS09820	ENOG4108K8U	Glycerol operon regulatory protein
E3Z27_RS09830	ENOG4105EMN	RNA polymerase sigma factor
E3Z27_RS09865	ENOG4105CGU	Enoyl-CoA hydratase
E3Z27_RS09870	ENOG4107QX3	carboxylase
E3Z27_RS09875	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS09880	ENOG4105CEY	Amp-dependent synthetase and ligase
E3Z27_RS09885	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E3Z27_RS09890	ENOG4108Z6Z	Transcriptional regulator
E3Z27_RS09900	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS09905	ENOG4108JZP	Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate (By similarity)
E3Z27_RS09930	ENOG4108T2Z	Arginine
E3Z27_RS09935	ENOG4105CUB	amino acid
E3Z27_RS09950	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E3Z27_RS09975	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E3Z27_RS09980	ENOG4105E89	ABC transporter
E3Z27_RS10005	ENOG4105DRB	nucleoside-specific channel-forming protein
E3Z27_RS10010	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
E3Z27_RS10015	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
E3Z27_RS10020	ENOG4107S21	permease
E3Z27_RS10030	ENOG4105CYM	Glutathione S-transferase
E3Z27_RS10035	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E3Z27_RS10040	ENOG4105D52	delta-aminolevulinic acid dehydratase
E3Z27_RS10045	ENOG4107QS8	(LipO)protein
E3Z27_RS10065	ENOG4105DY2	Paraquat-inducible protein b
E3Z27_RS10070	ENOG4105F1S	paraquat-inducible protein a
E3Z27_RS10080	ENOG41080XP	Cbs domain
E3Z27_RS10085	ENOG4105CQ2	DNA polymerase
E3Z27_RS10090	ENOG4108XM1	transcriptional regulator AsnC family
E3Z27_RS10100	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
E3Z27_RS10105	ENOG4107RCH	Diaminopropionate ammonia-lyase
E3Z27_RS10110	ENOG41061N2	exported protein
E3Z27_RS10115	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3Z27_RS10135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3Z27_RS10140	ENOG4105EB3	Histidine kinase
E3Z27_RS10145	ENOG4108HM4	ABC transporter
E3Z27_RS10165	ENOG41080QX	K07048 phosphotriesterase-related protein
E3Z27_RS10180	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS10185	ENOG4108HM4	ABC transporter
E3Z27_RS10190	ENOG4105CFQ	glutamine synthetase
E3Z27_RS10210	ENOG4105CV8	reductase
E3Z27_RS10215	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E3Z27_RS10225	ENOG4107TSN	permease
E3Z27_RS10245	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3Z27_RS10255	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3Z27_RS10260	ENOG4105C58	cytochrome c oxidase accessory protein ccog
E3Z27_RS10270	ENOG4108302	MgtC SapB transporter
E3Z27_RS10275	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
E3Z27_RS10285	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E3Z27_RS10300	ENOG41073TP	transcriptional regulator
E3Z27_RS10305	ENOG4105CHU	acetyl-coa acetyltransferase
E3Z27_RS10315	ENOG4105D6N	CoA-transferase, subunit a
E3Z27_RS10320	ENOG4108M0I	Transcriptional regulator
E3Z27_RS10325	ENOG4108N8X	transition metal ion binding
E3Z27_RS10345	ENOG4105WEF	catalase
E3Z27_RS10365	ENOG4105CSV	Glutaminase
E3Z27_RS10375	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3Z27_RS10385	ENOG4105CSH	Transporter
E3Z27_RS10400	ENOG4105MPD	Cytochrome
E3Z27_RS10420	ENOG4108R6W	Transcriptional regulator, ARAC family
E3Z27_RS10425	ENOG4108X79	transcriptional regulator
E3Z27_RS10430	ENOG4105CBX	hi0933 family
E3Z27_RS10465	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E3Z27_RS10480	ENOG4105C0B	DNA polymerase III (alpha subunit)
E3Z27_RS10485	ENOG4105CQZ	Histidine kinase
E3Z27_RS10510	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E3Z27_RS10525	ENOG4105ERU	peptidase
E3Z27_RS10545	ENOG4105C3R	Methionine synthase
E3Z27_RS10555	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
E3Z27_RS10560	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
E3Z27_RS10565	ENOG4108P62	biosynthesis protein (CbiG)
E3Z27_RS10580	ENOG4107QRP	cobalamin biosynthesis protein CobW
E3Z27_RS10610	ENOG4105K4U	addiction module toxin, RelE StbE family
E3Z27_RS10615	ENOG4107RP9	extracellular solute-binding protein, family 3
E3Z27_RS10620	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS10625	ENOG4105EAD	ABC transporter
E3Z27_RS10630	ENOG4105CDA	abc transporter atp-binding protein
E3Z27_RS10650	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
E3Z27_RS10655	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
E3Z27_RS10665	ENOG4105CZX	twitching motility protein
E3Z27_RS10670	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3Z27_RS10675	ENOG4105DTD	Dehydrogenase
E3Z27_RS10680	ENOG4105CY2	Citrate transporter
E3Z27_RS10685	ENOG4108JUA	Transcriptional regulator
E3Z27_RS10695	ENOG4107SDU	Methyl-accepting chemotaxis
E3Z27_RS10705	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E3Z27_RS10710	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E3Z27_RS10715	ENOG4105E43	Extracellular solute-binding protein, family 5
E3Z27_RS10720	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E3Z27_RS10735	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3Z27_RS10750	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E3Z27_RS10765	ENOG4105DFP	Integrase
E3Z27_RS10985	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3Z27_RS11040	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3Z27_RS11045	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3Z27_RS11060	ENOG4105DND	Transcriptional regulator
E3Z27_RS11070	ENOG4106HB6	Alpha beta hydrolase
E3Z27_RS11090	ENOG4105C82	Malate synthase
E3Z27_RS11095	ENOG4108ZJF	Glcg protein
E3Z27_RS11125	ENOG4105C26	Dehydrogenase
E3Z27_RS11140	ENOG4105E3J	oxidoreductase
E3Z27_RS11150	ENOG4107WT5	transcriptional regulator (NifA
E3Z27_RS11165	ENOG4105E7U	AraC family transcriptional regulator
E3Z27_RS11180	ENOG4105EWK	phytoene
E3Z27_RS11250	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS11280	ENOG4108IQK	o-acetylhomoserine
E3Z27_RS11285	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
E3Z27_RS11295	ENOG4105DUM	transcriptional regulator, lysR family
E3Z27_RS11305	ENOG4105C84	Histidine ammonia-lyase
E3Z27_RS11310	ENOG4105CGP	Urocanate hydratase
E3Z27_RS11315	ENOG4108JEH	abc transporter atp-binding protein
E3Z27_RS11320	ENOG4106YG3	ABC transporter
E3Z27_RS11325	ENOG4105DSP	amino acid AbC transporter
E3Z27_RS11330	ENOG4105E89	ABC transporter
E3Z27_RS11335	ENOG4105CZE	histidine utilization repressor
E3Z27_RS11340	ENOG4105E45	Histidinol-phosphate aminotransferase
E3Z27_RS11355	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E3Z27_RS11360	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS11400	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS11410	ENOG4108HM4	ABC transporter
E3Z27_RS11415	ENOG4108SHQ	Glutathione S-transferase
E3Z27_RS11440	ENOG4105X54	addiction module antidote protein
E3Z27_RS11445	ENOG4105CSP	Major Facilitator Superfamily
E3Z27_RS11450	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E3Z27_RS11455	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E3Z27_RS11485	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3Z27_RS11490	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3Z27_RS11495	ENOG4105EJC	lysr family transcriptional regulator
E3Z27_RS11520	ENOG4105D4T	Citrate transporter
E3Z27_RS11530	ENOG4108JQ1	Dehydrogenase
E3Z27_RS11565	ENOG4108V1U	phospholipid-binding protein
E3Z27_RS11570	ENOG4108UQN	AraC family transcriptional regulator
E3Z27_RS11605	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3Z27_RS11610	ENOG4105DHQ	Histidine kinase
E3Z27_RS11630	ENOG4105Q9Y	Universal stress protein
E3Z27_RS11635	ENOG41090JX	gCN5-related N-acetyltransferase
E3Z27_RS11640	ENOG41081QV	Universal stress protein
E3Z27_RS11655	ENOG4105Q9Y	Universal stress protein
E3Z27_RS11660	ENOG4105CY0	Metallo-Beta-Lactamase
E3Z27_RS11665	ENOG4105VN1	Heat shock protein
E3Z27_RS11670	ENOG4105D5Q	Arginine ornithine antiporter
E3Z27_RS11675	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E3Z27_RS11685	ENOG4105CMI	transporter
E3Z27_RS11690	ENOG4105CJ1	ABC, transporter
E3Z27_RS11695	ENOG4105D0S	secretion protein (HlyD
E3Z27_RS11700	ENOG4105CYB	regulatoR
E3Z27_RS11705	ENOG4105E0Y	RtcB Protein
E3Z27_RS11710	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
E3Z27_RS11715	ENOG4108WFR	AraC Family Transcriptional Regulator
E3Z27_RS11725	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3Z27_RS11735	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS11745	ENOG4105EMU	Dehydrogenase
E3Z27_RS11750	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3Z27_RS11770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3Z27_RS11775	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
E3Z27_RS11815	ENOG4108VBZ	doxx family
E3Z27_RS11830	ENOG4105HEI	LysR family (Transcriptional regulator
E3Z27_RS11835	ENOG4105CHR	reductase
E3Z27_RS11840	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E3Z27_RS11845	ENOG4105EU8	FAD linked oxidase domain protein
E3Z27_RS11850	ENOG4105CQB	FAD linked oxidase domain protein
E3Z27_RS11855	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
E3Z27_RS11875	ENOG4105CHR	reductase
E3Z27_RS11885	ENOG41060NJ	transcriptional regulator
E3Z27_RS11910	ENOG4107XBN	GntR Family Transcriptional Regulator
E3Z27_RS11920	ENOG4108IJ7	Glycine betaine
E3Z27_RS11925	ENOG4108HQS	Glycine betaine
E3Z27_RS11935	ENOG4105CTU	Proline racemase
E3Z27_RS11940	ENOG4105ECQ	AraC Family Transcriptional Regulator
E3Z27_RS11955	ENOG4105C54	Major Facilitator superfamily
E3Z27_RS11960	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3Z27_RS11965	ENOG4105C26	Dehydrogenase
E3Z27_RS11980	ENOG4108M0I	Transcriptional regulator
E3Z27_RS11990	ENOG4105UTS	cellulose synthase operon protein YhjQ
E3Z27_RS11995	ENOG4107QZ7	Cellulose synthase catalytic subunit
E3Z27_RS12000	ENOG4107EEX	Cellulose synthase regulator protein
E3Z27_RS12005	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
E3Z27_RS12010	ENOG4105EJG	cellulose synthase
E3Z27_RS12025	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E3Z27_RS12030	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
E3Z27_RS12045	ENOG4105E2A	Dehydrogenase
E3Z27_RS12050	ENOG4105CQ0	ABC transporter
E3Z27_RS12060	ENOG4105IBP	Cyclic peptide transporter
E3Z27_RS12065	ENOG4105CEY	Amp-dependent synthetase and ligase
E3Z27_RS12100	ENOG4107RBR	Receptor
E3Z27_RS12115	ENOG4107SDU	Methyl-accepting chemotaxis
E3Z27_RS12120	ENOG4105C26	Dehydrogenase
E3Z27_RS12125	ENOG4107SDU	Methyl-accepting chemotaxis
E3Z27_RS12135	ENOG4105CUB	amino acid
E3Z27_RS12150	ENOG4105CHR	reductase
E3Z27_RS12165	ENOG4108UAJ	Transcriptional regulator
E3Z27_RS12175	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS12190	ENOG4108V8F	Transcriptional regulator, MarR family
E3Z27_RS12205	ENOG4105CSP	Major Facilitator Superfamily
E3Z27_RS12215	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
E3Z27_RS12220	ENOG4105C26	Dehydrogenase
E3Z27_RS12240	ENOG4108V8F	Transcriptional regulator, MarR family
E3Z27_RS12275	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS12280	ENOG4105CQB	FAD linked oxidase domain protein
E3Z27_RS12285	ENOG4105CIR	epoxide hydrolase
E3Z27_RS12305	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
E3Z27_RS12310	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E3Z27_RS12315	ENOG4105D2S	major facilitator superfamily
E3Z27_RS12320	ENOG4105BZU	Histidine kinase
E3Z27_RS12330	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E3Z27_RS12340	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E3Z27_RS12410	ENOG4107SET	aldo keto reductase
E3Z27_RS12450	ENOG4105BZU	Histidine kinase
E3Z27_RS12470	ENOG4108HWW	ABC transporter
E3Z27_RS12475	ENOG4105C2J	ABC transporter
E3Z27_RS12480	ENOG4105DFW	ABC transporter
E3Z27_RS12485	ENOG4105C93	Xylose Isomerase
E3Z27_RS12490	ENOG4105T16	Transcriptional regulator (AraC family)
E3Z27_RS12495	ENOG4105RVE	Uncharacterized protein conserved in bacteria (DUF2136)
E3Z27_RS12500	ENOG4108Z3N	Transcriptional regulator
E3Z27_RS12525	ENOG4105F7F	Chaperone
E3Z27_RS12530	ENOG4105EVZ	LysR family transcriptional regulator
E3Z27_RS12545	ENOG4105DRP	amino acid AbC transporter
E3Z27_RS12550	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS12555	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3Z27_RS12565	ENOG4105C26	Dehydrogenase
E3Z27_RS12570	ENOG4105CTU	Proline racemase
E3Z27_RS12575	ENOG4105DRR	Transcriptional regulator, GntR family
E3Z27_RS12580	ENOG4108WYP	Transcriptional regulator
E3Z27_RS12600	ENOG4105BZU	Histidine kinase
E3Z27_RS12615	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E3Z27_RS12620	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3Z27_RS12655	ENOG4105BZU	Histidine kinase
E3Z27_RS12695	ENOG4105CIR	epoxide hydrolase
E3Z27_RS12720	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3Z27_RS12740	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E3Z27_RS12755	ENOG4107RUE	extracellular solute-binding protein family 1
E3Z27_RS12770	ENOG4108JJ6	Type I secretion system ATPase
E3Z27_RS12775	ENOG4107QZV	Type I secretion membrane fusion protein
E3Z27_RS12780	ENOG4105DFG	type I secretion outer membrane protein
E3Z27_RS12790	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
E3Z27_RS12800	ENOG4105EYH	Exonuclease
E3Z27_RS12805	ENOG4107RH8	nuclease SbcCD subunit D
E3Z27_RS12835	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E3Z27_RS12850	ENOG4105DJB	Major Facilitator Superfamily
E3Z27_RS12855	ENOG4105D7K	pfkb domain protein
E3Z27_RS12865	ENOG4108M60	Transcriptional regulator
E3Z27_RS12875	ENOG4105C7I	Dehydrogenase
E3Z27_RS12895	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E3Z27_RS12905	ENOG4105F87	Dehydratase
E3Z27_RS12930	ENOG4105VCD	cytoplasmic protein
E3Z27_RS12935	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS12945	ENOG4108M8W	Monooxygenase
E3Z27_RS12955	ENOG4105ETS	cytosine purines uracil thiamine allantoin
E3Z27_RS12965	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS12975	ENOG4105F38	ABC transporter, permease
E3Z27_RS12985	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3Z27_RS13000	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
E3Z27_RS13005	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E3Z27_RS13010	ENOG4105C26	Dehydrogenase
E3Z27_RS13020	ENOG4105C26	Dehydrogenase
E3Z27_RS13025	ENOG4108MXF	Alpha Beta Hydrolase
E3Z27_RS13040	ENOG4105C0W	non-ribosomal peptide synthetase
E3Z27_RS13080	ENOG4108KKZ	(LipO)protein
E3Z27_RS13085	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
E3Z27_RS13100	ENOG4105BZS	acriflavin resistance protein
E3Z27_RS13105	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3Z27_RS13110	ENOG4105E39	Enoyl-CoA hydratase
E3Z27_RS13115	ENOG4105E09	nadh pyrophosphatase
E3Z27_RS13145	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3Z27_RS13190	ENOG4105EPW	hflc protein
E3Z27_RS13200	ENOG4108MN8	Membrane
E3Z27_RS13215	ENOG4105C26	Dehydrogenase
E3Z27_RS13240	ENOG4105X23	Endonuclease Exonuclease phosphatase
E3Z27_RS13265	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
E3Z27_RS13270	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E3Z27_RS13275	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E3Z27_RS13280	ENOG4108JQ1	Dehydrogenase
E3Z27_RS13340	ENOG4105DG4	malate L-lactate dehydrogenase
E3Z27_RS13360	ENOG4105ES4	Nitrilase
E3Z27_RS13380	ENOG4105D6Z	AFG1 family ATPase
E3Z27_RS13385	ENOG4108R6G	acetyltransferase
E3Z27_RS13390	ENOG4105DIJ	Phosphoethanolamine transferase
E3Z27_RS13395	ENOG4108J5G	6-phosphogluconate dehydrogenase
E3Z27_RS13400	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E3Z27_RS13410	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3Z27_RS13470	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS13490	ENOG4105CC0	LysR family Transcriptional regulator
E3Z27_RS13495	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E3Z27_RS13510	ENOG4105C5H	ABC transporter
E3Z27_RS13520	ENOG4105DQE	DNA ligase
E3Z27_RS13525	ENOG4105FDF	Could be involved in DNA repair (By similarity)
E3Z27_RS13535	ENOG4105D8V	Glucose sorbosone dehydrogenase
E3Z27_RS13540	ENOG4105C7B	Threonine dehydratase
E3Z27_RS13555	ENOG4107Y7Q	pfkb domain protein
E3Z27_RS13560	ENOG4105CMG	Carbohydrate kinase
E3Z27_RS13565	ENOG4105DEI	Mannitol dehydrogenase
E3Z27_RS13580	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
E3Z27_RS13605	ENOG4105BZU	Histidine kinase
E3Z27_RS13610	ENOG4105BZU	Histidine kinase
E3Z27_RS13615	ENOG4107Z5C	methylesterase
E3Z27_RS13620	ENOG4105BZU	Histidine kinase
E3Z27_RS13665	ENOG4108JJ6	Type I secretion system ATPase
E3Z27_RS13670	ENOG4107QZV	Type I secretion membrane fusion protein
E3Z27_RS13685	ENOG4105GRZ	Ycii-related protein
E3Z27_RS13695	ENOG4106NDP	Transcriptional regulator
E3Z27_RS13700	ENOG4108HKT	sucrose-6-phosphate hydrolase
E3Z27_RS13705	ENOG4108IJ9	(ABC) transporter
E3Z27_RS13720	ENOG4107T3P	ABC, transporter
E3Z27_RS13730	ENOG4105BZ1	(ABC) transporter
E3Z27_RS13735	ENOG4105EXG	Transcriptional regulator
E3Z27_RS13745	ENOG410811B	TRANSCRIPTIONal
E3Z27_RS13755	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3Z27_RS13795	ENOG41088T4	Helicase IV
E3Z27_RS13825	ENOG4108JJ6	Type I secretion system ATPase
E3Z27_RS13830	ENOG4107QZV	Type I secretion membrane fusion protein
E3Z27_RS13835	ENOG4105DFG	type I secretion outer membrane protein
E3Z27_RS13855	ENOG4105F2V	VRR-NUC domain-containing protein
E3Z27_RS13895	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
E3Z27_RS13905	ENOG41069YE	inner membrane protein yohC
E3Z27_RS13910	ENOG4105CEV	competence damage-inducible protein
E3Z27_RS13920	ENOG4107VMU	Membrane
E3Z27_RS13925	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3Z27_RS13935	ENOG4105C87	Aminotransferase class I and II
E3Z27_RS13950	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E3Z27_RS13965	ENOG4105BZU	Histidine kinase
E3Z27_RS13970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3Z27_RS13985	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS13990	ENOG4105E39	Enoyl-CoA hydratase
E3Z27_RS14005	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
E3Z27_RS14015	ENOG4105CFM	UPF0317 protein
E3Z27_RS14020	ENOG4105EGI	Transcriptional regulator
E3Z27_RS14040	ENOG41060BG	Tetr family transcriptional regulator
E3Z27_RS14060	ENOG4105D25	secreted protein
E3Z27_RS14075	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS14095	ENOG4105CIS	alcohol dehydrogenase
E3Z27_RS14110	ENOG4105CK2	sodium dicarboxylate symporter
E3Z27_RS14115	ENOG4105HDK	L-asparaginase
E3Z27_RS14120	ENOG4105KME	endoribonuclease L-psp
E3Z27_RS14130	ENOG4105EJC	lysr family transcriptional regulator
E3Z27_RS14140	ENOG4108XM1	transcriptional regulator AsnC family
E3Z27_RS14200	ENOG4105J5J	Outer membrane porin
E3Z27_RS14210	ENOG4105CK2	sodium dicarboxylate symporter
E3Z27_RS14220	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E3Z27_RS14225	ENOG4105GAK	amidohydrolase 2
E3Z27_RS14230	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
E3Z27_RS14240	ENOG4108YIQ	Alpha beta hydrolase
E3Z27_RS14270	ENOG4105M0Y	
E3Z27_RS14310	ENOG4108Q9V	regulatoR
E3Z27_RS14360	ENOG4105CS6	Rhs element vgr protein
E3Z27_RS14385	ENOG41090KI	Outer membrane porin
E3Z27_RS14395	ENOG4105CK2	sodium dicarboxylate symporter
E3Z27_RS14400	ENOG4105C7F	AcnD-accessory protein PrpF
E3Z27_RS14405	ENOG4105F04	LysR family Transcriptional regulator
E3Z27_RS14410	ENOG4105CPW	cytochrome b561
E3Z27_RS14450	ENOG4105PGM	cation diffusion facilitator family transporter
E3Z27_RS14465	ENOG4105DND	Transcriptional regulator
E3Z27_RS14470	ENOG4107B2H	carbonic anhydrase
E3Z27_RS14515	ENOG4105CSP	Major Facilitator Superfamily
E3Z27_RS14540	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E3Z27_RS14550	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS14570	ENOG4108K3Z	AraC family transcriptional regulator
E3Z27_RS14575	ENOG4108JPW	Aminotransferase
E3Z27_RS14580	ENOG4105C26	Dehydrogenase
E3Z27_RS14585	ENOG4105DS1	cytochrome b561
E3Z27_RS14630	ENOG4105FDK	ABC transporter
E3Z27_RS14635	ENOG4105CC5	ABC transporter
E3Z27_RS14675	ENOG4105D5U	fad dependent oxidoreductase
E3Z27_RS14680	ENOG4108BAS	reductase
E3Z27_RS14690	ENOG4105ETS	cytosine purines uracil thiamine allantoin
E3Z27_RS14695	ENOG4105C26	Dehydrogenase
E3Z27_RS14700	ENOG4105C26	Dehydrogenase
E3Z27_RS14705	ENOG4105C26	Dehydrogenase
E3Z27_RS14735	ENOG4105C26	Dehydrogenase
E3Z27_RS14740	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E3Z27_RS14750	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS14755	ENOG4105E89	ABC transporter
E3Z27_RS14760	ENOG4108QBF	Transcriptional regulator
E3Z27_RS14765	ENOG4108K3Z	AraC family transcriptional regulator
E3Z27_RS14770	ENOG4105IKQ	hydratase
E3Z27_RS14805	ENOG4105C26	Dehydrogenase
E3Z27_RS14825	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E3Z27_RS14840	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS14845	ENOG4107NQ8	LysR family Transcriptional regulator
E3Z27_RS14855	ENOG4105MVE	transcriptional regulator
E3Z27_RS14860	ENOG4105BZU	Histidine kinase
E3Z27_RS14865	ENOG4105E39	Enoyl-CoA hydratase
E3Z27_RS14870	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS14875	ENOG4105CHU	acetyl-coa acetyltransferase
E3Z27_RS14890	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
E3Z27_RS14900	ENOG4105CKK	Glycosyl transferase, family 2
E3Z27_RS14910	ENOG4108UQN	AraC family transcriptional regulator
E3Z27_RS14915	ENOG4105JIM	Phosphatidylserine synthase
E3Z27_RS14940	ENOG4105JSC	dimethylmenaquinone methyltransferase
E3Z27_RS14950	ENOG4105DJU	Siderophore biosynthesis protein
E3Z27_RS14970	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3Z27_RS14975	ENOG4105DUU	IucA IucC family protein
E3Z27_RS14980	ENOG4108JPW	Aminotransferase
E3Z27_RS14995	ENOG4108SF5	RNA Polymerase
E3Z27_RS15015	ENOG4105BZU	Histidine kinase
E3Z27_RS15020	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3Z27_RS15025	ENOG41080XP	Cbs domain
E3Z27_RS15030	ENOG4107QZF	nitrite reductase NADPH large subunit
E3Z27_RS15035	ENOG4107QZF	nitrite reductase NADPH large subunit
E3Z27_RS15050	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E3Z27_RS15060	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3Z27_RS15070	ENOG4108ZJF	Glcg protein
E3Z27_RS15100	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
E3Z27_RS15110	ENOG4105EPF	Outer membrane porin
E3Z27_RS15115	ENOG4108SC4	)-transporter
E3Z27_RS15135	ENOG41062ES	Transcriptional regulator
E3Z27_RS15140	ENOG4105DWT	malate dehydrogenase (quinone)
E3Z27_RS15145	ENOG4105BZU	Histidine kinase
E3Z27_RS15160	ENOG4105C26	Dehydrogenase
E3Z27_RS15185	ENOG4105DZG	Dehydrogenase
E3Z27_RS15205	ENOG4105BZU	Histidine kinase
E3Z27_RS15225	ENOG4105CJ1	ABC, transporter
E3Z27_RS15245	ENOG4105BZU	Histidine kinase
E3Z27_RS15260	ENOG4105EQX	glucarate dehydratase
E3Z27_RS15270	ENOG4106NZI	LysR family Transcriptional regulator
E3Z27_RS15280	ENOG4105EXG	Transcriptional regulator
E3Z27_RS15285	ENOG4105VSH	4-oxalocrotonate tautomerase
E3Z27_RS15290	ENOG4105CHR	reductase
E3Z27_RS15305	ENOG4108SC4	)-transporter
E3Z27_RS15310	ENOG4105G3Z	GntR family transcriptional regulator
E3Z27_RS15320	ENOG4105CTU	Proline racemase
E3Z27_RS15325	ENOG41080HI	glycine oxidase
E3Z27_RS15340	ENOG4105FTV	AraC Family Transcriptional Regulator
E3Z27_RS15355	ENOG4108HW4	amino acid AbC transporter
E3Z27_RS15360	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS15365	ENOG4105CDA	abc transporter atp-binding protein
E3Z27_RS15370	ENOG4105CTU	Proline racemase
E3Z27_RS15375	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3Z27_RS15395	ENOG4105CPP	Dehydrogenase, E1 component
E3Z27_RS15405	ENOG4106Z86	ATP-nad acox kinase
E3Z27_RS15410	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E3Z27_RS15430	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3Z27_RS15435	ENOG4105E0F	Histidine kinase
E3Z27_RS15470	ENOG4107SCK	Monooxygenase
E3Z27_RS15480	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS15485	ENOG4105CMR	udp-glucose 4-epimerase
E3Z27_RS15510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3Z27_RS15525	ENOG4105C8Y	Acetylornithine aminotransferase
E3Z27_RS15565	ENOG4108K3Z	AraC family transcriptional regulator
E3Z27_RS15570	ENOG4105ECQ	AraC Family Transcriptional Regulator
E3Z27_RS15580	ENOG41064T2	transcriptional regulator, lysR family
E3Z27_RS15585	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E3Z27_RS15590	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E3Z27_RS15610	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E3Z27_RS15620	ENOG4105C26	Dehydrogenase
E3Z27_RS15625	ENOG4105CWC	Acetylornithine deacetylase
E3Z27_RS15635	ENOG4105KME	endoribonuclease L-psp
E3Z27_RS15640	ENOG4105H3G	oxidoreductase
E3Z27_RS15655	ENOG4105CFP	Peptidase U32
E3Z27_RS15685	ENOG4105HEE	Binding Domain protein
E3Z27_RS15705	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3Z27_RS15710	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3Z27_RS15720	ENOG41076YT	nitrate reductase, gamma subunit
E3Z27_RS15725	ENOG4108NZN	Respiratory nitrate reductase 2 delta chain
E3Z27_RS15730	ENOG4108IUE	nitrate reductase beta subunit
E3Z27_RS15735	ENOG4105CRU	nitrate reductase, alpha subunit
E3Z27_RS15740	ENOG4105DQQ	Major facilitator superfamily MFS_1
E3Z27_RS15750	ENOG4105BZU	Histidine kinase
E3Z27_RS15755	ENOG4105WH1	Two component transcriptional regulator luxr family
E3Z27_RS15770	ENOG4105XPQ	lipid carrier protein
E3Z27_RS15775	ENOG4106RZ4	Peptidase U32
E3Z27_RS15780	ENOG4105CFP	Peptidase U32
E3Z27_RS15785	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3Z27_RS15790	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E3Z27_RS15820	ENOG4105IJJ	transcriptional regulator, crp fnr family
E3Z27_RS15840	ENOG4108VKQ	nitriC oxide reductase
E3Z27_RS15860	ENOG4105F64	nitrite reductase
E3Z27_RS15900	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
E3Z27_RS15905	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E3Z27_RS15965	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3Z27_RS16010	ENOG4105IBP	Cyclic peptide transporter
E3Z27_RS16020	ENOG4105CEY	Amp-dependent synthetase and ligase
E3Z27_RS16045	ENOG4108K01	transcriptional regulator
E3Z27_RS16060	ENOG4105VEV	-acetyltransferase
E3Z27_RS16070	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS16090	ENOG4105WPR	Transcriptional regulator, ARAC family
E3Z27_RS16130	ENOG4105CEY	Amp-dependent synthetase and ligase
E3Z27_RS16150	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3Z27_RS16160	ENOG4105D4P	Coproporphyrinogen iii oxidase
E3Z27_RS16175	ENOG4107F2M	hemolysin-type calcium-binding region
E3Z27_RS16200	ENOG4105CMD	Transcriptional regulator, GntR family
E3Z27_RS16220	ENOG4105CD8	aminopeptidase N
E3Z27_RS16230	ENOG4105VUT	cytoplasmic protein
E3Z27_RS16240	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E3Z27_RS16245	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E3Z27_RS16260	ENOG41082YX	Transcriptional regulator, arsr family
E3Z27_RS16280	ENOG4108YYH	Nadph-dependent fmn reductase
E3Z27_RS16300	ENOG4107RZZ	dna polymerase iii epsilon subunit
E3Z27_RS16305	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3Z27_RS16315	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E3Z27_RS16320	ENOG4105E9H	Lytic Murein transglycosylase
E3Z27_RS16325	ENOG4105E43	Extracellular solute-binding protein, family 5
E3Z27_RS16330	ENOG4105E43	Extracellular solute-binding protein, family 5
E3Z27_RS16335	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E3Z27_RS16340	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E3Z27_RS16345	ENOG4108JQ5	ABC transporter
E3Z27_RS16350	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E3Z27_RS16355	ENOG410620I	Diguanylate cyclase
E3Z27_RS16370	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
E3Z27_RS16380	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3Z27_RS16390	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
E3Z27_RS16395	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E3Z27_RS16400	ENOG4105Q9Y	Universal stress protein
E3Z27_RS16410	ENOG4107QIJ	Aconitate hydratase 2
E3Z27_RS16415	ENOG4105C44	Serine transporter
E3Z27_RS16420	ENOG4105C5I	Dehydrogenase
E3Z27_RS16480	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3Z27_RS16490	ENOG4105CS6	Rhs element vgr protein
E3Z27_RS16510	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E3Z27_RS16535	ENOG4105D65	subunit l
E3Z27_RS16540	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E3Z27_RS16555	ENOG4105W4C	monovalent cation H antiporter subunit F
E3Z27_RS16560	ENOG4105KJM	monovalent cation h antiporter subunit g
E3Z27_RS16590	ENOG4108W2P	Methyl-accepting chemotaxis
E3Z27_RS16595	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3Z27_RS16600	ENOG4108HWV	)-transporter
E3Z27_RS16605	ENOG4105C2J	ABC transporter
E3Z27_RS16615	ENOG4105D9R	oxidoreductase
E3Z27_RS16620	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
E3Z27_RS16625	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
E3Z27_RS16635	ENOG4105DH8	myo-inositol catabolism
E3Z27_RS16650	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
E3Z27_RS16670	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3Z27_RS16675	ENOG4105BZU	Histidine kinase
E3Z27_RS16690	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
E3Z27_RS16695	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
E3Z27_RS16700	ENOG4105CD3	dihydroorotase
E3Z27_RS16705	ENOG4105BZ8	glutamate synthase
E3Z27_RS16710	ENOG4107SJI	Dehydrogenase
E3Z27_RS16715	ENOG4108R86	Transcriptional regulator
E3Z27_RS16720	ENOG41090KI	Outer membrane porin
E3Z27_RS16725	ENOG4105E9Z	Nad-dependent epimerase dehydratase
E3Z27_RS16745	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E3Z27_RS16765	ENOG4108YXU	transcriptional regulator AsnC family
E3Z27_RS16770	ENOG4107R0V	Pyruvate dehydrogenase
E3Z27_RS16775	ENOG4105CPP	Dehydrogenase, E1 component
E3Z27_RS16780	ENOG4107QSN	dihydrolipoamide acetyltransferase
E3Z27_RS16785	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3Z27_RS16790	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E3Z27_RS16805	ENOG4105D4Y	metalloprotease
E3Z27_RS16820	ENOG4105BZU	Histidine kinase
E3Z27_RS16825	ENOG4108RWI	nicotinamidase
E3Z27_RS16835	ENOG4105JJR	Histidine kinase
E3Z27_RS16840	ENOG4107EXC	regulatoR
E3Z27_RS16845	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E3Z27_RS16875	ENOG4108MGN	ATP-binding component of a transport system
E3Z27_RS16890	ENOG4105CHM	Aminotransferase
E3Z27_RS16900	ENOG4105BZW	Glycerate kinase
E3Z27_RS16905	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
E3Z27_RS16910	ENOG4105CSP	Major Facilitator Superfamily
E3Z27_RS16915	ENOG4105CPC	Aldo Keto reductase
E3Z27_RS16930	ENOG4108PCN	EamA-like transporter family
E3Z27_RS16935	ENOG4108M0I	Transcriptional regulator
E3Z27_RS16955	ENOG4108JU3	Alkyl hydroperoxide reductase
E3Z27_RS16960	ENOG4105D3R	alkyl hydroperoxide reductase
E3Z27_RS16965	ENOG4105DC8	reductase
E3Z27_RS16970	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E3Z27_RS17000	ENOG4105CF1	Alkylated DNA repair protein
E3Z27_RS17005	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3Z27_RS17020	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E3Z27_RS17025	ENOG4105E0C	molybdate abc transporter
E3Z27_RS17030	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS17060	ENOG4105EWT	decarboxylase family
E3Z27_RS17065	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
E3Z27_RS17070	ENOG4107QJQ	Mate efflux family protein
E3Z27_RS17080	ENOG4108VYJ	response regulator receiver protein
E3Z27_RS17090	ENOG4105CBS	Chea signal transduction histidine kinase
E3Z27_RS17095	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS17100	ENOG4108V3W	Chemotaxis protein, CheW
E3Z27_RS17105	ENOG4105BZU	Histidine kinase
E3Z27_RS17110	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
E3Z27_RS17115	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
E3Z27_RS17120	ENOG4108HQS	Glycine betaine
E3Z27_RS17130	ENOG4105BZU	Histidine kinase
E3Z27_RS17135	ENOG4108ZXC	Two component transcriptional regulator, luxr family
E3Z27_RS17165	ENOG4105CC0	LysR family Transcriptional regulator
E3Z27_RS17170	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
E3Z27_RS17175	ENOG4105QNJ	serralysin (EC 3.4.24.40)
E3Z27_RS17205	ENOG4108XDN	Transcriptional regulator
E3Z27_RS17220	ENOG4105EMU	Dehydrogenase
E3Z27_RS17235	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E3Z27_RS17265	ENOG4105EU0	Major facilitator Superfamily
E3Z27_RS17295	ENOG4108RYR	transcriptional regulator AsnC family
E3Z27_RS17305	ENOG4108JPW	Aminotransferase
E3Z27_RS17310	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
E3Z27_RS17315	ENOG4108SZE	gCN5-related N-acetyltransferase
E3Z27_RS17325	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E3Z27_RS17335	ENOG4105CWC	Acetylornithine deacetylase
E3Z27_RS17340	ENOG4105DDR	sarcosine oxidase (Beta subunit)
E3Z27_RS17360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS17370	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3Z27_RS17375	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS17410	ENOG4108UQ8	endoribonuclease L-psp
E3Z27_RS17435	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3Z27_RS17440	ENOG4105E0F	Histidine kinase
E3Z27_RS17465	ENOG4107S5I	aldo keto reductase
E3Z27_RS17470	ENOG410642W	LysR family Transcriptional regulator
E3Z27_RS17485	ENOG4105KME	endoribonuclease L-psp
E3Z27_RS17500	ENOG4105DAA	L-lactate
E3Z27_RS17515	ENOG4105EAA	nucleoside
E3Z27_RS17530	ENOG4105ETE	Transcriptional regulator (LacI family
E3Z27_RS17580	ENOG4108W2Y	isochorismatase
E3Z27_RS17605	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
E3Z27_RS17610	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E3Z27_RS17615	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
E3Z27_RS17620	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
E3Z27_RS17625	ENOG4107QYG	anthranilate phosphoribosyltransferase
E3Z27_RS17630	ENOG4105CHF	Glutathione S-transferase
E3Z27_RS17635	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E3Z27_RS17645	ENOG4105WMR	Protein CrcB homolog
E3Z27_RS17650	ENOG4105D1H	recombination factor protein RarA
E3Z27_RS17655	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E3Z27_RS17660	ENOG4105CNU	cell division protein FtsK
E3Z27_RS17665	ENOG4105C3M	thioredoxin reductase
E3Z27_RS17670	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E3Z27_RS17675	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
E3Z27_RS17680	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E3Z27_RS17685	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3Z27_RS17690	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E3Z27_RS17695	ENOG4105VEQ	Cold shock protein
E3Z27_RS17705	ENOG4105E9K	Isocitrate dehydrogenase
E3Z27_RS17715	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E3Z27_RS17720	ENOG41075W9	High frequency lysogenization protein HflD homolog
E3Z27_RS17730	ENOG4105EZE	Cupin 4 family protein
E3Z27_RS17735	ENOG41082BV	acetyltransferase
E3Z27_RS17745	ENOG4108I9X	Isocitrate lyase
E3Z27_RS17750	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3Z27_RS17755	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3Z27_RS17760	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3Z27_RS17765	ENOG4105GKE	subunit e
E3Z27_RS17770	ENOG4107QIZ	NADH dehydrogenase
E3Z27_RS17775	ENOG4108IEH	NADH dehydrogenase subunit g
E3Z27_RS17780	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
E3Z27_RS17785	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3Z27_RS17790	ENOG4107UFS	subunit j
E3Z27_RS17795	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3Z27_RS17800	ENOG4105D65	subunit l
E3Z27_RS17810	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3Z27_RS17820	ENOG4105MVE	transcriptional regulator
E3Z27_RS17825	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E3Z27_RS17830	ENOG4105C6Z	Gluconate
E3Z27_RS17835	ENOG4105FB2	class II Aldolase
E3Z27_RS17840	ENOG4105G63	Type III effector Hrp-dependent
E3Z27_RS17845	ENOG4105ZXK	Dehydrogenase
E3Z27_RS17850	ENOG4105D5U	fad dependent oxidoreductase
E3Z27_RS17860	ENOG4105CC0	LysR family Transcriptional regulator
E3Z27_RS17865	ENOG4105CHJ	isochorismatase hydrolase
E3Z27_RS17930	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS17955	ENOG4108IG5	Transcriptional regulator
E3Z27_RS17980	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E3Z27_RS17995	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3Z27_RS18000	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E3Z27_RS18005	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E3Z27_RS18010	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E3Z27_RS18020	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E3Z27_RS18025	ENOG4105C22	threonyL-tRNA synthetase
E3Z27_RS18060	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
E3Z27_RS18065	ENOG4108RVA	ribokinase
E3Z27_RS18070	ENOG4105ETE	Transcriptional regulator (LacI family
E3Z27_RS18075	ENOG4105CNN	ABC, transporter
E3Z27_RS18080	ENOG4105C2J	ABC transporter
E3Z27_RS18085	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
E3Z27_RS18115	ENOG4105C8N	cysteinyl-tRNA synthetase
E3Z27_RS18120	ENOG4105CX6	glutaminyL-tRNA synthetase
E3Z27_RS18130	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E3Z27_RS18140	ENOG4105CW7	secretion protein, HlyD family
E3Z27_RS18150	ENOG41090MY	MarR family Transcriptional regulator
E3Z27_RS18160	ENOG4105CFU	surface antigen
E3Z27_RS18170	ENOG4105CGK	Exodeoxyribonuclease III
E3Z27_RS18175	ENOG4107QKZ	Ompa motb domain protein
E3Z27_RS18190	ENOG4107UB2	Alpha beta hydrolase fold
E3Z27_RS18195	ENOG4105E32	cytoplasmic protein
E3Z27_RS18200	ENOG4108WC9	type VI secretion system effector, hcp1 family
E3Z27_RS18225	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3Z27_RS18230	ENOG4105EXC	Acyl-transferase
E3Z27_RS18240	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E3Z27_RS18340	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
E3Z27_RS18350	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS18355	ENOG4108IJ9	(ABC) transporter
E3Z27_RS18360	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E3Z27_RS18390	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3Z27_RS18420	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS18425	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
E3Z27_RS18635	ENOG4105CDU	Replicative dna helicase
E3Z27_RS18640	ENOG4106CVF	DNA replication protein
E3Z27_RS18675	ENOG4105W7J	DNA binding
E3Z27_RS18795	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS18800	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E3Z27_RS18810	ENOG4107U9B	transcriptional regulator
E3Z27_RS18815	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E3Z27_RS18835	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
E3Z27_RS18840	ENOG4105C28	cystathionine
E3Z27_RS18845	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E3Z27_RS18850	ENOG4105E96	Colicin v production protein
E3Z27_RS18855	ENOG41063M6	Cell Division Protein
E3Z27_RS18860	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E3Z27_RS18865	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E3Z27_RS18870	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E3Z27_RS18875	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E3Z27_RS18885	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3Z27_RS18890	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3Z27_RS18895	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E3Z27_RS18900	ENOG4105F2W	methyltransferase
E3Z27_RS18905	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3Z27_RS18910	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3Z27_RS18915	ENOG4108MP6	LysR family Transcriptional regulator
E3Z27_RS18920	ENOG4105BZU	Histidine kinase
E3Z27_RS18930	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E3Z27_RS18940	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E3Z27_RS18975	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E3Z27_RS18980	ENOG4105CGF	Aromatic amino acid aminotransferase
E3Z27_RS19000	ENOG4108REF	Sporulation integral membrane protein ytvi
E3Z27_RS19010	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS19015	ENOG4105D3Y	Na H antiporter
E3Z27_RS19025	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3Z27_RS19045	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
E3Z27_RS19060	ENOG4105DZC	cytosine deaminase
E3Z27_RS19065	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E3Z27_RS19070	ENOG4106UW1	Major Facilitator superfamily
E3Z27_RS19080	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E3Z27_RS19090	ENOG4105EUB	pirin domain protein
E3Z27_RS19110	ENOG4105BZU	Histidine kinase
E3Z27_RS19120	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
E3Z27_RS19125	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E3Z27_RS19130	ENOG4105BZP	glycoside hydrolase 15-related
E3Z27_RS19155	ENOG4105EMU	Dehydrogenase
E3Z27_RS19160	ENOG4105CF7	AraC family transcriptional regulator
E3Z27_RS19170	ENOG4105VTN	Protein of unknown function (DUF1311)
E3Z27_RS19200	ENOG4107AQZ	Membrane
E3Z27_RS19215	ENOG4105C3J	Cysteine desulfurase
E3Z27_RS19235	ENOG4108Z4X	TRANSCRIPTIONal
E3Z27_RS19245	ENOG4105C7F	AcnD-accessory protein PrpF
E3Z27_RS19250	ENOG4108I0Z	Aconitate hydratase
E3Z27_RS19255	ENOG4105BZN	citrate synthase
E3Z27_RS19260	ENOG4105CR4	methylisocitrate lyase
E3Z27_RS19265	ENOG4105DRR	Transcriptional regulator, GntR family
E3Z27_RS19270	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E3Z27_RS19280	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E3Z27_RS19290	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
E3Z27_RS19300	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
E3Z27_RS19305	ENOG410633P	Hydantoin racemase
E3Z27_RS19310	ENOG410642W	LysR family Transcriptional regulator
E3Z27_RS19315	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
E3Z27_RS19320	ENOG4107YBY	Hydrolase
E3Z27_RS19360	ENOG4108SXK	Transporter Drug Metabolite Exporter family
E3Z27_RS19380	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS19385	ENOG4105C5I	Dehydrogenase
E3Z27_RS19390	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E3Z27_RS19400	ENOG4105DJB	Major Facilitator Superfamily
E3Z27_RS19445	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E3Z27_RS19450	ENOG4105D7N	magnesium and cobalt transport protein CorA
E3Z27_RS19455	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3Z27_RS19460	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3Z27_RS19465	ENOG4105CHU	acetyl-coa acetyltransferase
E3Z27_RS19495	ENOG4105VV6	START domain-containing protein
E3Z27_RS19510	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3Z27_RS19530	ENOG4105C10	Electron transfer flavoprotein
E3Z27_RS19535	ENOG4105BZJ	Electron transfer flavoprotein
E3Z27_RS19540	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E3Z27_RS19550	ENOG4105DQ4	alcohol dehydrogenase
E3Z27_RS19555	ENOG4107HP6	Transcriptional regulator
E3Z27_RS19560	ENOG4105DJB	Major Facilitator Superfamily
E3Z27_RS19565	ENOG4105CXK	mandelate racemase muconate lactonizing
E3Z27_RS19570	ENOG4108RTU	Aldolase
E3Z27_RS19575	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
E3Z27_RS19600	ENOG4105CNN	ABC, transporter
E3Z27_RS19605	ENOG4105C2J	ABC transporter
E3Z27_RS19610	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
E3Z27_RS19615	ENOG4108R85	Short chain dehydrogenase
E3Z27_RS19625	ENOG4107EJG	GntR family transcriptional regulator
E3Z27_RS19640	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3Z27_RS19650	ENOG4105F8V	Hydrolase, tatD family
E3Z27_RS19660	ENOG4107QRG	dna polymerase iii
E3Z27_RS19665	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E3Z27_RS19670	ENOG4105HHA	aminodeoxychorismate lyase
E3Z27_RS19680	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E3Z27_RS19685	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E3Z27_RS19690	ENOG4105CHR	reductase
E3Z27_RS19695	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3Z27_RS19700	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E3Z27_RS19705	ENOG4105VGS	50s ribosomal protein l32
E3Z27_RS19710	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E3Z27_RS19715	ENOG4108UHJ	MAF-like protein
E3Z27_RS19720	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E3Z27_RS19730	ENOG4105EI2	Pseudouridine synthase
E3Z27_RS19735	ENOG4107QQB	Ribonuclease E
E3Z27_RS19745	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
E3Z27_RS19760	ENOG4105D4A	Cell wall formation (By similarity)
E3Z27_RS19775	ENOG4105W49	UPF0434 protein
E3Z27_RS19780	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E3Z27_RS19785	ENOG4109015	Biopolymer transport protein exbD tolR
E3Z27_RS19795	ENOG4108EC8	DNA internalization-related competence protein ComEC
E3Z27_RS19805	ENOG4105E3A	(ABC) transporter
E3Z27_RS19810	ENOG4105DA5	(ABC) transporter
E3Z27_RS19815	ENOG4108TGY	Glutathione S-transferase
E3Z27_RS19820	ENOG4107QPN	acyl-Coa dehydrogenase
E3Z27_RS19945	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS19955	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E3Z27_RS19960	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E3Z27_RS19965	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
E3Z27_RS19975	ENOG4105E0F	Histidine kinase
E3Z27_RS19985	ENOG4105IPI	Membrane
E3Z27_RS20005	ENOG4105KA0	thioesterase Superfamily protein
E3Z27_RS20020	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E3Z27_RS20025	ENOG4107RNH	Outer membrane receptor FepA
E3Z27_RS20035	ENOG4105BZU	Histidine kinase
E3Z27_RS20040	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
E3Z27_RS20055	ENOG4105EUB	pirin domain protein
E3Z27_RS20065	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E3Z27_RS20090	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E3Z27_RS20095	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E3Z27_RS20100	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E3Z27_RS20105	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3Z27_RS20110	ENOG4105C7S	Dehydrogenase
E3Z27_RS20115	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E3Z27_RS20120	ENOG4105E33	succinate dehydrogenase
E3Z27_RS20125	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
E3Z27_RS20130	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E3Z27_RS20135	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E3Z27_RS20145	ENOG4107QN1	sodium solute
E3Z27_RS20150	ENOG41062QD	Membrane
E3Z27_RS20165	ENOG410903C	(LipO)protein
E3Z27_RS20170	ENOG4105CKW	Inner membrane protein yedI
E3Z27_RS20175	ENOG4108R86	Transcriptional regulator
E3Z27_RS20195	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E3Z27_RS20200	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E3Z27_RS20210	ENOG4105CA9	Pyruvate kinase
E3Z27_RS20220	ENOG4105EYW	Ion transport protein
E3Z27_RS20225	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E3Z27_RS20230	ENOG4105EQ0	Major Facilitator superfamily
E3Z27_RS20245	ENOG4105JXB	ankyrin repeat-containing protein
E3Z27_RS20260	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
E3Z27_RS20265	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
E3Z27_RS20270	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
E3Z27_RS20280	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E3Z27_RS20285	ENOG4105F6J	Alpha beta hydrolase fold
E3Z27_RS20310	ENOG4108DG9	Smr protein MutS2
E3Z27_RS20320	ENOG4105M5P	UPF0310 protein
E3Z27_RS20330	ENOG4105EUJ	GTP cyclohydrolase i
E3Z27_RS20340	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3Z27_RS20350	ENOG4105C7N	Xanthine uracil vitamin C permease
E3Z27_RS20380	ENOG4105VT2	5-hydroxyisourate hydrolase
E3Z27_RS20395	ENOG4105DHG	Allantoate amidinohydrolase
E3Z27_RS20400	ENOG4108Z2U	ureidoglycolate hydrolase
E3Z27_RS20420	ENOG4105D1S	lipid A biosynthesis
E3Z27_RS20425	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E3Z27_RS20430	ENOG4107QMS	site-determining protein
E3Z27_RS20435	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
E3Z27_RS20440	ENOG4105D3G	Pseudouridine synthase
E3Z27_RS20445	ENOG4105DFM	M18 family aminopeptidase
E3Z27_RS20470	ENOG4105F38	ABC transporter, permease
E3Z27_RS20515	ENOG4105BZU	Histidine kinase
E3Z27_RS20530	ENOG4105CNA	YD repeat protein
E3Z27_RS20550	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3Z27_RS20595	ENOG4105HEI	LysR family (Transcriptional regulator
E3Z27_RS20600	ENOG4105CC0	LysR family Transcriptional regulator
E3Z27_RS20635	ENOG4105J5J	Outer membrane porin
E3Z27_RS20640	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3Z27_RS20645	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E3Z27_RS20655	ENOG4108M1T	Cytochrome c-type biogenesis protein
E3Z27_RS20660	ENOG4105KWW	Biogenesis protein
E3Z27_RS20670	ENOG4105DA4	cytochrome c-type biogenesis protein
E3Z27_RS20675	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
E3Z27_RS20685	ENOG41060IM	Heme exporter protein
E3Z27_RS20690	ENOG4108UAU	isochorismatase
E3Z27_RS20705	ENOG4105RE0	Asp Glu hydantoin racemase
E3Z27_RS20715	ENOG4105QPS	Monooxygenase
E3Z27_RS20720	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS20725	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3Z27_RS20760	ENOG4105EPF	Outer membrane porin
E3Z27_RS20765	ENOG4105CSH	Transporter
E3Z27_RS20795	ENOG4105XUA	cytochrome c
E3Z27_RS20825	ENOG4105D5U	fad dependent oxidoreductase
E3Z27_RS20830	ENOG4108ZX5	transcriptional regulator
E3Z27_RS20875	ENOG4108IYH	Dna topoisomerase
E3Z27_RS20900	ENOG4105W5Q	DNA repair protein (RadC
E3Z27_RS21065	ENOG4107QPV	Serine Threonine protein kinase
E3Z27_RS21105	ENOG4105DFP	Integrase
E3Z27_RS21120	ENOG4105DH7	May be involved in recombination (By similarity)
E3Z27_RS21125	ENOG4105C09	Bile acid
E3Z27_RS21130	ENOG4105KPY	Small multidrug resistance protein
E3Z27_RS21135	ENOG4107S74	Lysophospholipid transporter LplT
E3Z27_RS21160	ENOG4105BZU	Histidine kinase
E3Z27_RS21165	ENOG4105CGY	Dna recombination protein
E3Z27_RS21185	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
E3Z27_RS21205	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
E3Z27_RS21210	ENOG4108TGR	phosphatase
E3Z27_RS21215	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
E3Z27_RS21220	ENOG4108YZT	Adenosylcobinamide kinase
E3Z27_RS21225	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E3Z27_RS21230	ENOG4105EFT	decarboxylase
E3Z27_RS21235	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
E3Z27_RS21240	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
E3Z27_RS21245	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
E3Z27_RS21250	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
E3Z27_RS21270	ENOG4105K4H	Nlp p60 protein
E3Z27_RS21275	ENOG4107TT5	NLP P60 protein
E3Z27_RS21280	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
E3Z27_RS21285	ENOG4105C02	permease
E3Z27_RS21295	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E3Z27_RS21300	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E3Z27_RS21320	ENOG4105DXN	mazG family
E3Z27_RS21325	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3Z27_RS21330	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E3Z27_RS21335	ENOG4105C6T	cysteine synthase
E3Z27_RS21365	ENOG4108MBX	Secretion Protein
E3Z27_RS21370	ENOG4108JJA	ABC, transporter
E3Z27_RS21385	ENOG410804D	Sensor Signal Transduction Histidine Kinase
E3Z27_RS21395	ENOG4105BZU	Histidine kinase
E3Z27_RS21400	ENOG4105C5I	Dehydrogenase
E3Z27_RS21425	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E3Z27_RS21435	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E3Z27_RS21440	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E3Z27_RS21445	ENOG41069YE	inner membrane protein yohC
E3Z27_RS21450	ENOG4105GPY	SprT protein
E3Z27_RS21455	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E3Z27_RS21465	ENOG4105ID8	Transcriptional regulator, ARAC family
E3Z27_RS21475	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3Z27_RS21495	ENOG4105JJR	Histidine kinase
E3Z27_RS21500	ENOG4107EXC	regulatoR
E3Z27_RS21505	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3Z27_RS21510	ENOG4105BZE	flagellar hook protein, FlgE
E3Z27_RS21515	ENOG4105W00	Flagellar hook capping protein
E3Z27_RS21520	ENOG4108ZC9	flagellar basal-body rod protein flgc
E3Z27_RS21525	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
E3Z27_RS21530	ENOG4105BZU	Histidine kinase
E3Z27_RS21535	ENOG4107R88	Chemotaxis protein (CheV)
E3Z27_RS21555	ENOG4106825	Type iv pilus assembly
E3Z27_RS21560	ENOG4108ISG	Major Facilitator
E3Z27_RS21570	ENOG4105ES5	Histidine kinase
E3Z27_RS21580	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS21585	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3Z27_RS21595	ENOG4108JQ1	Dehydrogenase
E3Z27_RS21600	ENOG4108SB3	DoxX Family
E3Z27_RS21605	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E3Z27_RS21610	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E3Z27_RS21620	ENOG4108W5M	transcriptional regulator
E3Z27_RS21625	ENOG4108K3A	Glutathione S-transferase
E3Z27_RS21650	ENOG4105CJW	magnesium transporter
E3Z27_RS21680	ENOG4105CFH	Aspartokinase
E3Z27_RS21685	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E3Z27_RS21690	ENOG4105C5W	Aldolase
E3Z27_RS21695	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E3Z27_RS21700	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
E3Z27_RS21710	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
E3Z27_RS21720	ENOG4105F4X	arginine
E3Z27_RS21725	ENOG4108T2Z	Arginine
E3Z27_RS21730	ENOG4105C8Y	Acetylornithine aminotransferase
E3Z27_RS21735	ENOG4105ECQ	AraC Family Transcriptional Regulator
E3Z27_RS21740	ENOG4108JEH	abc transporter atp-binding protein
E3Z27_RS21750	ENOG4105DSP	amino acid AbC transporter
E3Z27_RS21755	ENOG4105E89	ABC transporter
E3Z27_RS21760	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3Z27_RS21770	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3Z27_RS21800	ENOG410630P	Transcriptional regulator
E3Z27_RS21815	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E3Z27_RS21820	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
E3Z27_RS21830	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
E3Z27_RS21850	ENOG4105F9N	Major Facilitator Superfamily
E3Z27_RS21860	ENOG4105C85	amino acid
E3Z27_RS21875	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E3Z27_RS21885	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E3Z27_RS21890	ENOG4105DB7	PHP domain protein
E3Z27_RS21895	ENOG4107835	probably involved in intracellular septation (By similarity)
E3Z27_RS21900	ENOG4105K9H	YciI-like protein
E3Z27_RS21910	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3Z27_RS21920	ENOG4105DHQ	Histidine kinase
E3Z27_RS21940	ENOG410624X	efflux transporter, rnd family, mfp subunit
E3Z27_RS21950	ENOG4105FQR	PH-inducible protein involved in stress response
E3Z27_RS21975	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E3Z27_RS21995	ENOG4105CHR	reductase
E3Z27_RS22005	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E3Z27_RS22010	ENOG4105DGN	Electron transport complex
E3Z27_RS22015	ENOG4108R3D	Electron transport complex
E3Z27_RS22020	ENOG4105D6A	Electron transport complex
E3Z27_RS22025	ENOG4108UQQ	Electron transport complex
E3Z27_RS22035	ENOG4105CSM	endonuclease III
E3Z27_RS22045	ENOG4108WQH	regulatoR
E3Z27_RS22055	ENOG4105CDH	Citrulline--aspartate ligase
E3Z27_RS22065	ENOG4105EKE	dihydroorotase
E3Z27_RS22070	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E3Z27_RS22075	ENOG4105D3R	alkyl hydroperoxide reductase
E3Z27_RS22080	ENOG4105W53	bacterioferritin-associated ferredoxin
E3Z27_RS22085	ENOG4108UQY	Iron-storage protein
E3Z27_RS22090	ENOG4105M2J	Glutaredoxin
E3Z27_RS22095	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E3Z27_RS22105	ENOG4105DBV	ornithine carbamoyltransferase
E3Z27_RS22110	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS22115	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E3Z27_RS22120	ENOG4108Z66	YbaK ebsC protein
E3Z27_RS22140	ENOG4107RP9	extracellular solute-binding protein, family 3
E3Z27_RS22145	ENOG4105EAD	ABC transporter
E3Z27_RS22150	ENOG4105DRP	amino acid AbC transporter
E3Z27_RS22155	ENOG4105CDA	abc transporter atp-binding protein
E3Z27_RS22160	ENOG4105CQZ	Histidine kinase
E3Z27_RS22165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS22170	ENOG4105RA2	Membrane
E3Z27_RS22175	ENOG4108RYK	Nad-dependent epimerase dehydratase
E3Z27_RS22185	ENOG4105EJC	lysr family transcriptional regulator
E3Z27_RS22195	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E3Z27_RS22200	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E3Z27_RS22205	ENOG4105EJQ	L-serine dehydratase
E3Z27_RS22225	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E3Z27_RS22230	ENOG4105E3B	Multicopper oxidase
E3Z27_RS22250	ENOG4105DJ2	Major Facilitator Superfamily
E3Z27_RS22265	ENOG4105C8Y	Acetylornithine aminotransferase
E3Z27_RS22270	ENOG4105C8Y	Acetylornithine aminotransferase
E3Z27_RS22290	ENOG4105G2Y	Transcriptional regulator
E3Z27_RS22305	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E3Z27_RS22310	ENOG4105UFD	tol-pal system protein YbgF
E3Z27_RS22315	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E3Z27_RS22320	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E3Z27_RS22330	ENOG4105M8F	Biopolymer transport protein exbD tolR
E3Z27_RS22335	ENOG4105E02	MotA TolQ exbB proton channel
E3Z27_RS22340	ENOG4107YD3	Thioesterase
E3Z27_RS22345	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E3Z27_RS22350	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E3Z27_RS22355	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E3Z27_RS22360	ENOG4105CDY	transcriptional regulatory protein
E3Z27_RS22365	ENOG4105C9M	aspartyl-trna synthetase
E3Z27_RS22385	ENOG4105VEQ	Cold shock protein
E3Z27_RS22390	ENOG41069P5	Protein slyX homolog
E3Z27_RS22400	ENOG4105J5J	Outer membrane porin
E3Z27_RS22410	ENOG4108VPT	UPF0234 protein
E3Z27_RS22415	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E3Z27_RS22425	ENOG4108WBT	adenosyltransferase
E3Z27_RS22430	ENOG4105M6F	mutator MutT protein
E3Z27_RS22440	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E3Z27_RS22455	ENOG4105D7A	ATP-binding protein
E3Z27_RS22465	ENOG4105BZF	Glycosyl transferase (Group 1
E3Z27_RS22490	ENOG4105CJB	Exodeoxyribonuclease I
E3Z27_RS22515	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E3Z27_RS22570	ENOG4105CA9	Pyruvate kinase
E3Z27_RS22575	ENOG4107QK7	reductase
E3Z27_RS22580	ENOG4105BZU	Histidine kinase
E3Z27_RS22585	ENOG4107GFK	fumarate
E3Z27_RS22610	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS22615	ENOG4105CSH	Transporter
E3Z27_RS22645	ENOG4105CF7	AraC family transcriptional regulator
E3Z27_RS22650	ENOG4105C7K	acetolactate synthase
E3Z27_RS22655	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS22660	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E3Z27_RS22665	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E3Z27_RS22670	ENOG4105DZ2	Transcriptional regulator
E3Z27_RS22675	ENOG4107TCE	N-acetyltransferase
E3Z27_RS22685	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3Z27_RS22690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E3Z27_RS22695	ENOG4105BZU	Histidine kinase
E3Z27_RS22700	ENOG4105BZU	Histidine kinase
E3Z27_RS22705	ENOG4105CA0	peroxidase
E3Z27_RS22710	ENOG4105BZU	Histidine kinase
E3Z27_RS22720	ENOG4105CBC	glutamate synthase
E3Z27_RS22730	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
E3Z27_RS22735	ENOG4105C85	amino acid
E3Z27_RS22785	ENOG4105NTW	Transcriptional regulator
E3Z27_RS22790	ENOG4105Q26	Siderophore-interacting protein
E3Z27_RS22800	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
E3Z27_RS22805	ENOG4105DZG	Dehydrogenase
E3Z27_RS22810	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
E3Z27_RS22825	ENOG4108Z0R	Transferase
E3Z27_RS22830	ENOG4105P8F	nudix hydrolase
E3Z27_RS22860	ENOG4105FDP	GntR family transcriptional regulator
E3Z27_RS22865	ENOG4105CE4	GlcNAc 6-P deacetylase
E3Z27_RS22870	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E3Z27_RS22875	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E3Z27_RS22880	ENOG4105CI1	PTS System
E3Z27_RS22895	ENOG4108ETH	Formylglycinamide ribotide synthetase
E3Z27_RS22900	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3Z27_RS22905	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E3Z27_RS22910	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E3Z27_RS22915	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E3Z27_RS22920	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E3Z27_RS22925	ENOG4105C3F	Signal peptidase i
E3Z27_RS22930	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E3Z27_RS22940	ENOG4108M8S	permease YjgP YjgQ family protein
E3Z27_RS22945	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E3Z27_RS22950	ENOG4105MYG	DNA polymerase iii, chi subunit
E3Z27_RS22960	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E3Z27_RS22975	ENOG4106V8H	Nucleoid-associated protein
E3Z27_RS22990	ENOG41082IR	Excinuclease ABC C subunit domain protein
E3Z27_RS23000	ENOG4105DJ2	Major Facilitator Superfamily
E3Z27_RS23005	ENOG4105JXH	GntR family transcriptional regulator
E3Z27_RS23020	ENOG4105CDA	abc transporter atp-binding protein
E3Z27_RS23030	ENOG4105EZ7	amino acid ABC transporter
E3Z27_RS23040	ENOG4106CJB	Phospholipase Carboxylesterase
E3Z27_RS23045	ENOG4105C1J	atp-dependent rna helicase
E3Z27_RS23055	ENOG4105FC8	fad dependent oxidoreductase
E3Z27_RS23060	ENOG4108SGR	YheO domain-containing protein
E3Z27_RS23070	ENOG4105E89	ABC transporter
E3Z27_RS23075	ENOG4108ZAF	Molybdopterin
E3Z27_RS23080	ENOG4105M00	molybdopterin converting factor, subunit 1
E3Z27_RS23085	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3Z27_RS23090	ENOG4108IAB	Phoh family
E3Z27_RS23100	ENOG4108ZJ4	polysaccharide deacetylase
E3Z27_RS23105	ENOG4105D1Q	UPF0246 protein
E3Z27_RS23110	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E3Z27_RS23115	ENOG4105KZJ	alginate biosynthesis protein Alg8
E3Z27_RS23120	ENOG4108UIA	Alginate biosynthesis protein Alg44
E3Z27_RS23125	ENOG4105XJP	alginate biosynthesis protein
E3Z27_RS23130	ENOG4105Y9T	outer membrane protein AlgE
E3Z27_RS23135	ENOG4108C0K	Bifunctional protein that converts poly(beta-D- mannuronate) to alpha-L-guluronate and that is also part of a periplasmic protein complex that serves as a scaffold that leads the newly formed alginate polymer through the periplasmic space to the outer membrane secretin AlgE
E3Z27_RS23140	ENOG4105JHR	Alginate biosynthesis protein AlgX
E3Z27_RS23145	ENOG4105FN4	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond (By similarity)
E3Z27_RS23150	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
E3Z27_RS23155	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
E3Z27_RS23160	ENOG4105ZJ4	Together with AlgI and AlgJ, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate is important for the architecture of biofilms and increases
E3Z27_RS23165	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
E3Z27_RS23185	ENOG4105E1F	short-chain dehydrogenase reductase
E3Z27_RS23190	ENOG4105Y49	secretion protein, HlyD family
E3Z27_RS23210	ENOG4105CR8	Transcriptional regulator
E3Z27_RS23225	ENOG4105BZS	acriflavin resistance protein
E3Z27_RS23235	ENOG4105GR3	Histidine kinase
E3Z27_RS23245	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3Z27_RS23250	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E3Z27_RS23255	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E3Z27_RS23260	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E3Z27_RS23265	ENOG4105CPF	Cell wall formation (By similarity)
E3Z27_RS23270	ENOG4105DFU	Cell wall formation (By similarity)
E3Z27_RS23275	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E3Z27_RS23280	ENOG4105CNI	cell division protein FtsW
E3Z27_RS23285	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E3Z27_RS23290	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E3Z27_RS23295	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E3Z27_RS23300	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E3Z27_RS23305	ENOG4105CJN	penicillin-binding protein
E3Z27_RS23315	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E3Z27_RS23320	ENOG4108V6E	Cell division protein mraZ
E3Z27_RS23330	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E3Z27_RS23335	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E3Z27_RS23340	ENOG41082RQ	UPF0102 protein
E3Z27_RS23345	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
E3Z27_RS23350	ENOG4105W4M	Transport-associated protein
E3Z27_RS23360	ENOG4105KB2	stringent starvation protein b
E3Z27_RS23365	ENOG4107MKT	Stringent starvation protein a
E3Z27_RS23370	ENOG4105EIX	cytochrome c1
E3Z27_RS23375	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E3Z27_RS23380	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E3Z27_RS23385	ENOG4108UJD	30S ribosomal protein S9
E3Z27_RS23390	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E3Z27_RS23395	ENOG4105CPC	Aldo Keto reductase
E3Z27_RS23400	ENOG4105C1G	acyl-Coa dehydrogenase
E3Z27_RS23410	ENOG4105D6Z	AFG1 family ATPase
E3Z27_RS23415	ENOG4105C31	Tryptophanyl-tRNA synthetase
E3Z27_RS23430	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3Z27_RS23435	ENOG41061ZR	Transcriptional regulator
E3Z27_RS23440	ENOG4105D25	secreted protein
E3Z27_RS23450	ENOG4105CEY	Amp-dependent synthetase and ligase
E3Z27_RS23455	ENOG4105EQK	-acetyltransferase
E3Z27_RS23465	ENOG4105C5I	Dehydrogenase
E3Z27_RS23470	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E3Z27_RS23480	ENOG4108K0D	peptidase, M48
E3Z27_RS23485	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS23490	ENOG4108RAV	Conserved protein
E3Z27_RS23530	ENOG4105DWT	malate dehydrogenase (quinone)
E3Z27_RS23545	ENOG4105CHH	sulfate transporter
E3Z27_RS23555	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E3Z27_RS23560	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E3Z27_RS23565	ENOG4105C2W	permease
E3Z27_RS23570	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E3Z27_RS23575	ENOG4105ECP	epimerase
E3Z27_RS23580	ENOG4108QDE	fad dependent oxidoreductase
E3Z27_RS23590	ENOG4108XDN	Transcriptional regulator
E3Z27_RS23595	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E3Z27_RS23610	ENOG41061N2	exported protein
E3Z27_RS23615	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E3Z27_RS23620	ENOG4105D06	uba thif-type nad fad binding protein
E3Z27_RS23625	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E3Z27_RS23630	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E3Z27_RS23635	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E3Z27_RS23640	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
E3Z27_RS23645	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E3Z27_RS23650	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E3Z27_RS23660	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E3Z27_RS23665	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E3Z27_RS23670	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E3Z27_RS23675	ENOG4105C3G	gtp-binding protein
E3Z27_RS23695	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3Z27_RS23700	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS23705	ENOG4105EE5	Membrane protein terC
E3Z27_RS23710	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E3Z27_RS23735	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E3Z27_RS23740	ENOG4105VMP	Transcriptional regulator
E3Z27_RS23750	ENOG4107SDU	Methyl-accepting chemotaxis
E3Z27_RS23755	ENOG4105CRW	Short chain fatty acid transporter
E3Z27_RS23770	ENOG41077A9	carbonic anhydrase
E3Z27_RS23780	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E3Z27_RS23805	ENOG4105DY2	Paraquat-inducible protein b
E3Z27_RS23810	ENOG4105F1S	paraquat-inducible protein a
E3Z27_RS23815	ENOG4105F1S	paraquat-inducible protein a
E3Z27_RS23845	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
E3Z27_RS23850	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E3Z27_RS23855	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E3Z27_RS23860	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E3Z27_RS23865	ENOG4108ZP8	Acetolactate synthase small subunit
E3Z27_RS23870	ENOG4105C7K	acetolactate synthase
E3Z27_RS23880	ENOG4105DR9	pseudouridine synthase
E3Z27_RS23890	ENOG4105BZ4	penicillin-binding protein
E3Z27_RS23920	ENOG4105PW4	Sugar fermentation stimulation protein homolog
E3Z27_RS23930	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3Z27_RS23935	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E3Z27_RS23945	ENOG4105BZU	Histidine kinase
E3Z27_RS23950	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS23955	ENOG4105DJ0	Poly(A) Polymerase
E3Z27_RS23960	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3Z27_RS23965	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E3Z27_RS23970	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E3Z27_RS23975	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E3Z27_RS23980	ENOG4107QP8	phosphohexose isomerase
E3Z27_RS23985	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3Z27_RS23990	ENOG4105DR4	Methyltransferase
E3Z27_RS24005	ENOG4105W4M	Transport-associated protein
E3Z27_RS24015	ENOG4107QHF	type ii secretion system protein e
E3Z27_RS24030	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E3Z27_RS24035	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E3Z27_RS24060	ENOG4105CEP	NADH dehydrogenase
E3Z27_RS24090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3Z27_RS24095	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E3Z27_RS24100	ENOG4105C34	Pseudouridine synthase
E3Z27_RS24105	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3Z27_RS24110	ENOG4107TUY	Histidine kinase
E3Z27_RS24115	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS24125	ENOG4108DN8	FAD dependent oxidoreductase
E3Z27_RS24165	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E3Z27_RS24170	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E3Z27_RS24175	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E3Z27_RS24180	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E3Z27_RS24185	ENOG4105DTN	riboflavin biosynthesis protein ribF
E3Z27_RS24190	ENOG4105CJR	Integral membrane protein (MviN
E3Z27_RS24195	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E3Z27_RS24200	ENOG4108RH0	Crea protein
E3Z27_RS24205	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E3Z27_RS24210	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E3Z27_RS24215	ENOG4105K46	50S ribosomal protein l27
E3Z27_RS24220	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E3Z27_RS24225	ENOG4105EAH	synthase
E3Z27_RS24230	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E3Z27_RS24240	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3Z27_RS24245	ENOG4108TEB	UPF0114 protein
E3Z27_RS24255	ENOG4105DAN	ATP-dependent protease
E3Z27_RS24275	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E3Z27_RS24280	ENOG4105C5H	ABC transporter
E3Z27_RS24285	ENOG4105BZU	Histidine kinase
E3Z27_RS24290	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E3Z27_RS24315	ENOG4105CKI	cobalamin synthesis protein
E3Z27_RS24320	ENOG4105VCD	cytoplasmic protein
E3Z27_RS24335	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E3Z27_RS24350	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E3Z27_RS24355	ENOG4105DP0	ferredoxin-NADP reductase
E3Z27_RS24365	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
E3Z27_RS24375	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E3Z27_RS24380	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E3Z27_RS24390	ENOG4105C7W	Xanthine dehydrogenase
E3Z27_RS24395	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
E3Z27_RS24400	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
E3Z27_RS24415	ENOG4107S0N	DJ-1 family
E3Z27_RS24425	ENOG4105C7N	Xanthine uracil vitamin C permease
E3Z27_RS24430	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
E3Z27_RS24435	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E3Z27_RS24440	ENOG4107S9B	Shikimate dehydrogenase
E3Z27_RS24445	ENOG4108W9H	Tetr family transcriptional regulator
E3Z27_RS24450	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E3Z27_RS24470	ENOG4105CGZ	zinc metallopeptidase
E3Z27_RS24485	ENOG4105C29	acyl-CoA thioesterase
E3Z27_RS24490	ENOG4108YYQ	gCN5-related N-acetyltransferase
E3Z27_RS24495	ENOG4105DGU	Histone deacetylase
E3Z27_RS24505	ENOG4105C1J	atp-dependent rna helicase
E3Z27_RS24510	ENOG4105FDR	Membrane
E3Z27_RS24520	ENOG4105DVT	helicase
E3Z27_RS24530	ENOG4105G4C	Periplasmic ligand-binding sensor protein
E3Z27_RS24535	ENOG4108S3I	UPF0259 membrane protein
E3Z27_RS24545	ENOG4105CQ7	ATP-dependent helicase
E3Z27_RS24555	ENOG41076HS	cation diffusion facilitator family transporter
E3Z27_RS24565	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
E3Z27_RS24575	ENOG4108R99	pseudouridine synthase
E3Z27_RS24580	ENOG4105FYV	Amp nucleosidase
E3Z27_RS24585	ENOG4105CSU	acyl-Coa dehydrogenase
E3Z27_RS24590	ENOG4105BZU	Histidine kinase
E3Z27_RS24595	ENOG4105DWF	phosphomethylpyrimidine kinase
E3Z27_RS24600	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E3Z27_RS24605	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E3Z27_RS24620	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E3Z27_RS24625	ENOG4105C9A	Phoh family
E3Z27_RS24630	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E3Z27_RS24635	ENOG4108JU5	Magnesium and cobalt efflux protein
E3Z27_RS24640	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E3Z27_RS24655	ENOG4105C8T	Leucyl-tRNA synthetase
E3Z27_RS24675	ENOG4105CVE	Lytic murein transglycosylase
E3Z27_RS24680	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E3Z27_RS24685	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E3Z27_RS24690	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E3Z27_RS24700	ENOG4105DZ1	carboxypeptidase
E3Z27_RS24710	ENOG4105CVE	Lytic murein transglycosylase
E3Z27_RS24715	ENOG4105CNI	cell division protein FtsW
E3Z27_RS24720	ENOG4105CJN	penicillin-binding protein
E3Z27_RS24725	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E3Z27_RS24740	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E3Z27_RS24745	ENOG4108RB4	3-methyladenine DNA glycosylase
E3Z27_RS24750	ENOG4108KF1	Membrane
E3Z27_RS24760	ENOG41067MG	lrgb family
E3Z27_RS24780	ENOG4105K4T	epimerase
E3Z27_RS24790	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E3Z27_RS24795	ENOG4105DFU	Cell wall formation (By similarity)
E3Z27_RS24800	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E3Z27_RS24805	ENOG4105C26	Dehydrogenase
E3Z27_RS24815	ENOG4105CPD	ethanolamine ammonia-lyase
E3Z27_RS24820	ENOG4107FQ9	ethanolamine ammonia-lyase
E3Z27_RS24825	ENOG4105KD7	acetyltransferase
E3Z27_RS24830	ENOG4105DQR	SNARE associated Golgi
E3Z27_RS24835	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
E3Z27_RS24840	ENOG4105F0N	pyrophosphate phospho-hydrolase
E3Z27_RS24845	ENOG4108XTP	Transcriptional regulator
E3Z27_RS24930	ENOG4107R3N	Filamentation induced by cAMP protein fic
E3Z27_RS24950	ENOG4108JA1	polyketide synthase
E3Z27_RS24975	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
E3Z27_RS24980	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
E3Z27_RS24985	ENOG41077RS	Phosphatase
E3Z27_RS25000	ENOG4108HPI	phosphatidate Cytidylyltransferase
E3Z27_RS25015	ENOG4105K4U	addiction module toxin, RelE StbE family
E3Z27_RS25020	ENOG4105EDV	vault protein
E3Z27_RS25025	ENOG41081SK	signal peptide protein
E3Z27_RS25030	ENOG4107S52	alpha-2-macroglobulin domain protein
E3Z27_RS25035	ENOG4108QJJ	Protein of unknown function (DUF1175)
E3Z27_RS25040	ENOG4107FKF	Uncharacterized protein conserved in bacteria (DUF2138)
E3Z27_RS25045	ENOG4105EDV	vault protein
E3Z27_RS25050	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E3Z27_RS25055	ENOG4105CTB	Polyprenyl synthetase
E3Z27_RS25060	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E3Z27_RS25070	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E3Z27_RS25080	ENOG4108ZAI	phosphatidylglycerophosphatase a
E3Z27_RS25085	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E3Z27_RS25090	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E3Z27_RS25095	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E3Z27_RS25100	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3Z27_RS25110	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E3Z27_RS25115	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E3Z27_RS25125	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E3Z27_RS25130	ENOG4107QR8	Thioredoxin
E3Z27_RS25145	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3Z27_RS25160	ENOG4105EIF	outer membrane protein W
E3Z27_RS25165	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E3Z27_RS25175	ENOG4107QRT	dEAD DEAH box helicase
E3Z27_RS25180	ENOG4105D8X	mechanosensitive ion channel
E3Z27_RS25190	ENOG4105X23	Endonuclease Exonuclease phosphatase
E3Z27_RS25195	ENOG4105DZQ	phospholipase D Transphosphatidylase
E3Z27_RS25200	ENOG4107UXM	Membrane
E3Z27_RS25220	ENOG4108W2Y	isochorismatase
E3Z27_RS25225	ENOG4108UUM	single-stranded DNA-binding protein
E3Z27_RS25230	ENOG4107RDB	Major Facilitator
E3Z27_RS25235	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E3Z27_RS25240	ENOG4108UWD	Iron-storage protein
E3Z27_RS25250	ENOG4108ZT0	50S ribosomal protein l17
E3Z27_RS25260	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E3Z27_RS25265	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E3Z27_RS25270	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E3Z27_RS25280	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E3Z27_RS25285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E3Z27_RS25290	ENOG4105VPB	50S ribosomal protein L30
E3Z27_RS25295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E3Z27_RS25300	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E3Z27_RS25305	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E3Z27_RS25310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E3Z27_RS25315	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E3Z27_RS25325	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E3Z27_RS25330	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E3Z27_RS25335	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E3Z27_RS25340	ENOG41083MP	50s ribosomal protein l29
E3Z27_RS25345	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E3Z27_RS25350	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E3Z27_RS25360	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E3Z27_RS25365	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E3Z27_RS25370	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E3Z27_RS25375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E3Z27_RS25385	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E3Z27_RS25390	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E3Z27_RS25395	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E3Z27_RS25400	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E3Z27_RS25405	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E3Z27_RS25410	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3Z27_RS25415	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3Z27_RS25420	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E3Z27_RS25425	ENOG4108VZM	50s ribosomal protein L10
E3Z27_RS25430	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E3Z27_RS25435	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E3Z27_RS25440	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E3Z27_RS25445	ENOG4105PM1	preprotein translocase subunit SecE
E3Z27_RS25455	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E3Z27_RS25480	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E3Z27_RS25485	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E3Z27_RS25515	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E3Z27_RS25525	ENOG4105DR5	peptidase
E3Z27_RS25530	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E3Z27_RS25535	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E3Z27_RS25540	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E3Z27_RS25545	ENOG4108YXA	Membrane
E3Z27_RS25565	ENOG4107YU2	histidine triad (hIT) protein
E3Z27_RS25570	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
E3Z27_RS25575	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
E3Z27_RS25580	ENOG4108UKZ	OsmC family
E3Z27_RS25585	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E3Z27_RS25595	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E3Z27_RS25600	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E3Z27_RS25605	ENOG4105DDQ	anthranilate synthase
E3Z27_RS25610	ENOG4108FHP	Autotransporter beta-domain
E3Z27_RS25615	ENOG4105CRQ	synthase (Component I)
E3Z27_RS25620	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3Z27_RS25625	ENOG4105DJV	ribulose-phosphate 3-epimerase
E3Z27_RS25630	ENOG4105C0A	alcohol dehydrogenase
E3Z27_RS25640	ENOG4105F38	ABC transporter, permease
E3Z27_RS25650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS25655	ENOG4105WH1	Two component transcriptional regulator luxr family
E3Z27_RS25660	ENOG4105ENE	Histidine kinase
E3Z27_RS25670	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
E3Z27_RS25675	ENOG4105EHM	Aminoglycoside phosphotransferase
E3Z27_RS25685	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E3Z27_RS25690	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E3Z27_RS25695	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E3Z27_RS25700	ENOG4105NWN	ApaG protein
E3Z27_RS25705	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E3Z27_RS25710	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E3Z27_RS25715	ENOG4105CYN	Serine protein kinase
E3Z27_RS25720	ENOG4106AKX	UPF0229 protein
E3Z27_RS25725	ENOG4105ED1	spovr family
E3Z27_RS25730	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E3Z27_RS25735	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3Z27_RS25740	ENOG4107ZVW	dihydroneopterin aldolase
E3Z27_RS25745	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E3Z27_RS25750	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E3Z27_RS25755	ENOG4105VCC	30S ribosomal protein S21
E3Z27_RS25760	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E3Z27_RS25770	ENOG4105BZU	Histidine kinase
E3Z27_RS25820	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
E3Z27_RS25825	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
E3Z27_RS25830	ENOG4106URE	pyrroloquinoline quinone biosynthesis protein d
E3Z27_RS25835	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
E3Z27_RS25850	ENOG4105CSU	acyl-Coa dehydrogenase
E3Z27_RS25855	ENOG4105CSU	acyl-Coa dehydrogenase
E3Z27_RS25860	ENOG4106TD9	Diguanylate cyclase
E3Z27_RS25865	ENOG4105CSU	acyl-Coa dehydrogenase
E3Z27_RS25885	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E3Z27_RS25890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3Z27_RS25895	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
E3Z27_RS25905	ENOG4105F4R	Transcriptional regulator mode
E3Z27_RS25915	ENOG4105E27	serine threonine protein kinase
E3Z27_RS25920	ENOG4105FR1	rard protein
E3Z27_RS25935	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS25950	ENOG4108SF5	RNA Polymerase
E3Z27_RS25955	ENOG4108S3W	Anti-feci sigma factor, fecr
E3Z27_RS25960	ENOG4105E0K	tonB-dependent siderophore receptor
E3Z27_RS25970	ENOG4105DPW	Major facilitator superfamily MFS_1
E3Z27_RS25975	ENOG4108U78	Glutathione S-transferase
E3Z27_RS25980	ENOG4105CT7	inner membrane cred family protein
E3Z27_RS25985	ENOG4105EB3	Histidine kinase
E3Z27_RS25990	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3Z27_RS25995	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
E3Z27_RS26000	ENOG4106HNH	Acyl-transferase
E3Z27_RS26045	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E3Z27_RS26060	ENOG4108UK5	Transposase
E3Z27_RS26065	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E3Z27_RS26070	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
E3Z27_RS26100	ENOG4105C10	Electron transfer flavoprotein
E3Z27_RS26105	ENOG4105DF6	Fe-S oxidoreductase
E3Z27_RS26145	ENOG4105ECQ	AraC Family Transcriptional Regulator
E3Z27_RS26155	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
E3Z27_RS26160	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
E3Z27_RS26185	ENOG4105ECQ	AraC Family Transcriptional Regulator
E3Z27_RS26190	ENOG4105EJQ	L-serine dehydratase
E3Z27_RS26200	ENOG4108HQS	Glycine betaine
E3Z27_RS26205	ENOG4108IJ7	Glycine betaine
E3Z27_RS26210	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
E3Z27_RS26215	ENOG4105C26	Dehydrogenase
E3Z27_RS26220	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
E3Z27_RS26230	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
E3Z27_RS26235	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E3Z27_RS26240	ENOG4105C1J	atp-dependent rna helicase
E3Z27_RS26245	ENOG4105CBX	hi0933 family
E3Z27_RS26250	ENOG4105EM2	membrane
E3Z27_RS26270	ENOG4108VKG	metal-dependent hydrolase
E3Z27_RS26300	ENOG4105D2N	Aldolase
E3Z27_RS26315	ENOG4105BZA	Phosphoglycerate kinase
E3Z27_RS26320	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3Z27_RS26330	ENOG4105YVS	arsR family transcriptional regulator
E3Z27_RS26340	ENOG4108NIW	Leucine export protein LeuE
E3Z27_RS26375	ENOG4105F27	Major Facilitator
E3Z27_RS26380	ENOG4105S64	Formate nitrite transporter
E3Z27_RS26390	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E3Z27_RS26395	ENOG4105SYT	Methylenetetrahydrofolate reductase
E3Z27_RS26405	ENOG4105C1J	atp-dependent rna helicase
E3Z27_RS26410	ENOG4108YYC	ycei family
E3Z27_RS26415	ENOG4105DS1	cytochrome b561
E3Z27_RS26435	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E3Z27_RS26440	ENOG4107RP9	extracellular solute-binding protein, family 3
E3Z27_RS26445	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E3Z27_RS26455	ENOG4108UT2	hemolysin iii
E3Z27_RS26460	ENOG4108K70	Transcriptional regulator
E3Z27_RS26475	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3Z27_RS26480	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
E3Z27_RS26495	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
E3Z27_RS26500	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
E3Z27_RS26525	ENOG4105CBS	Chea signal transduction histidine kinase
E3Z27_RS26530	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS26535	ENOG4108ZGA	chew protein
E3Z27_RS26540	ENOG4105M3Z	response regulator
E3Z27_RS26545	ENOG4108UNF	response regulator
E3Z27_RS26550	ENOG4105D7Z	glutathione synthase
E3Z27_RS26560	ENOG4108UJU	UPF0301 protein
E3Z27_RS26565	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E3Z27_RS26570	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E3Z27_RS26580	ENOG4105CD3	dihydroorotase
E3Z27_RS26590	ENOG4105K4H	Nlp p60 protein
E3Z27_RS26595	ENOG4105CZX	twitching motility protein
E3Z27_RS26600	ENOG4105DFA	alanine racemase domain protein
E3Z27_RS26605	ENOG4105II7	pyrroline-5-carboxylate reductase
E3Z27_RS26610	ENOG4108VIA	integral membrane protein
E3Z27_RS26615	ENOG4105DWV	Homoserine O-trans-acetylase
E3Z27_RS26620	ENOG4105DWV	Homoserine O-trans-acetylase
E3Z27_RS26630	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E3Z27_RS26635	ENOG4105CSA	Coproporphyrinogen iii oxidase
E3Z27_RS26645	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E3Z27_RS26650	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E3Z27_RS26655	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E3Z27_RS26665	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E3Z27_RS26670	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3Z27_RS26675	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
E3Z27_RS26680	ENOG4105CAK	Cell division ATP-binding protein ftsE
E3Z27_RS26685	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E3Z27_RS26700	ENOG4106H78	methyltransferase
E3Z27_RS26705	ENOG4105DNZ	Alpha Beta Hydrolase
E3Z27_RS26710	ENOG4105KHC	sulfurtransferase
E3Z27_RS26720	ENOG4107RGH	Aldehyde dehydrogenase
E3Z27_RS26735	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E3Z27_RS26740	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E3Z27_RS26750	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E3Z27_RS26760	ENOG4105DR4	Methyltransferase
E3Z27_RS26775	ENOG4105CZQ	inner membrane transport protein YdhC
E3Z27_RS26780	ENOG4105C01	Dihydroxy-acid dehydratase
E3Z27_RS26790	ENOG4108ETY	sodium dicarboxylate symporter
E3Z27_RS26805	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E3Z27_RS26855	ENOG4105D38	putrescine abc transporter
E3Z27_RS26860	ENOG4105F38	ABC transporter, permease
E3Z27_RS26865	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS26870	ENOG4108HM4	ABC transporter
E3Z27_RS26880	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
E3Z27_RS26885	ENOG4105CFQ	glutamine synthetase
E3Z27_RS26890	ENOG4105CFQ	glutamine synthetase
E3Z27_RS26900	ENOG4105F4R	Transcriptional regulator mode
E3Z27_RS26905	ENOG4105E2Y	ABC, transporter
E3Z27_RS26910	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS26915	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
E3Z27_RS26920	ENOG4105GVF	(ABC) transporter
E3Z27_RS26930	ENOG4105D3R	alkyl hydroperoxide reductase
E3Z27_RS26940	ENOG4105J5J	Outer membrane porin
E3Z27_RS26950	ENOG4105CWC	Acetylornithine deacetylase
E3Z27_RS26960	ENOG4108XM1	transcriptional regulator AsnC family
E3Z27_RS26970	ENOG4107QHF	type ii secretion system protein e
E3Z27_RS26980	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E3Z27_RS26985	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E3Z27_RS26990	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
E3Z27_RS26995	ENOG4107QKW	extracellular solute-binding protein family 1
E3Z27_RS27000	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E3Z27_RS27005	ENOG4105D0A	hydroxylase
E3Z27_RS27010	ENOG4107RAQ	aminopeptidase
E3Z27_RS27015	ENOG4105E07	UPF0149 protein
E3Z27_RS27025	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
E3Z27_RS27035	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E3Z27_RS27055	ENOG4105CXY	transporter
E3Z27_RS27070	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E3Z27_RS27075	ENOG4105EXC	Acyl-transferase
E3Z27_RS27085	ENOG4105K63	Thioredoxin
E3Z27_RS27090	ENOG4108HW3	(ABC) transporter
E3Z27_RS27100	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS27105	ENOG4105CDA	abc transporter atp-binding protein
E3Z27_RS27110	ENOG4105C9X	ppx gppa phosphatase
E3Z27_RS27115	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E3Z27_RS27120	ENOG4105D52	delta-aminolevulinic acid dehydratase
E3Z27_RS27125	ENOG4105KHU	inner membrane protein YohD
E3Z27_RS27135	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
E3Z27_RS27140	ENOG4108UPT	UPF0178 protein
E3Z27_RS27145	ENOG4107SJW	iron permease, FTR1
E3Z27_RS27190	ENOG410829K	Lysine exporter protein (Lyse ygga)
E3Z27_RS27200	ENOG4105C5H	ABC transporter
E3Z27_RS27220	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
E3Z27_RS27225	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E3Z27_RS27235	ENOG41076E6	Uroporphyrinogen-III Synthase
E3Z27_RS27240	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E3Z27_RS27245	ENOG4108NEV	two component transcriptional regulator, LytTR family
E3Z27_RS27250	ENOG4105CH7	arginosuccinase
E3Z27_RS27255	ENOG4105IU3	Glutathione S-transferase
E3Z27_RS27270	ENOG4107T0K	Adenylate cyclase
E3Z27_RS27275	ENOG4105NXH	GreA GreB family elongation factor
E3Z27_RS27285	ENOG4105XQ6	frataxin-like protein
E3Z27_RS27295	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3Z27_RS27300	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E3Z27_RS27310	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3Z27_RS27315	ENOG4105PAD	Hydrolase
E3Z27_RS27325	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
E3Z27_RS27330	ENOG4105BZU	Histidine kinase
E3Z27_RS27335	ENOG4108YZA	Nitrogen regulatory protein pii
E3Z27_RS27340	ENOG4105W0Z	cytoplasmic protein
E3Z27_RS27355	ENOG4105C0P	Mg chelatase subunit ChlI
E3Z27_RS27365	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS27370	ENOG4105ETT	transcriptional Regulator, LysR family
E3Z27_RS27380	ENOG4105BZU	Histidine kinase
E3Z27_RS27385	ENOG4105C4R	Atp-dependent dna helicase
E3Z27_RS27390	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
E3Z27_RS27395	ENOG4105CYC	Transferase
E3Z27_RS27400	ENOG4105MPD	Cytochrome
E3Z27_RS27410	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3Z27_RS27415	ENOG4105M4H	endoribonuclease L-psp
E3Z27_RS27420	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E3Z27_RS27425	ENOG4105EW9	transcriptional regulator AsnC family
E3Z27_RS27435	ENOG4105CJP	fad dependent oxidoreductase
E3Z27_RS27445	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3Z27_RS27460	ENOG4105C26	Dehydrogenase
E3Z27_RS27470	ENOG4105W0E	50S ribosomal protein L33
E3Z27_RS27475	ENOG4105KDC	50s ribosomal protein l28
E3Z27_RS27480	ENOG4105DEF	Extracellular solute-binding protein, family 5
E3Z27_RS27485	ENOG4105W5Q	DNA repair protein (RadC
E3Z27_RS27490	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E3Z27_RS27495	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E3Z27_RS27500	ENOG4107QKV	phosphomannomutase
E3Z27_RS27505	ENOG4105CAS	nag kinase
E3Z27_RS27510	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E3Z27_RS27515	ENOG4105CGK	Exodeoxyribonuclease III
E3Z27_RS27525	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E3Z27_RS27530	ENOG4105DSJ	YicC domain protein
E3Z27_RS27535	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E3Z27_RS27540	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E3Z27_RS27545	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3Z27_RS27550	ENOG4105KME	endoribonuclease L-psp
E3Z27_RS27600	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3Z27_RS27605	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3Z27_RS27640	ENOG41080P2	Phosphatase
E3Z27_RS27645	ENOG4105D9P	serine threonine protein kinase
E3Z27_RS27660	ENOG4108ZZF	transport protein (ExbD)
E3Z27_RS27665	ENOG4105YHG	TonB family
E3Z27_RS27670	ENOG4105C5Q	Transcriptional regulator
E3Z27_RS27675	ENOG4105CB5	ATP-dependent DNA helicase recG
E3Z27_RS27730	ENOG4105D9P	serine threonine protein kinase
E3Z27_RS27750	ENOG4106VK6	Flagellar motor protein
E3Z27_RS27785	ENOG4108WC9	type VI secretion system effector, hcp1 family
E3Z27_RS27815	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3Z27_RS27820	ENOG4105CS6	Rhs element vgr protein
E3Z27_RS27830	ENOG4107TV1	YD repeat protein
E3Z27_RS27870	ENOG4105NYX	DNA-binding protein
E3Z27_RS27875	ENOG4107QZF	nitrite reductase NADPH large subunit
E3Z27_RS27885	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
E3Z27_RS27890	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E3Z27_RS27900	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3Z27_RS27905	ENOG4105BZU	Histidine kinase
E3Z27_RS27915	ENOG4105DR5	peptidase
E3Z27_RS27925	ENOG4108VYJ	response regulator receiver protein
E3Z27_RS27930	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E3Z27_RS27935	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E3Z27_RS27940	ENOG4105C8U	phosphate abc transporter
E3Z27_RS27955	ENOG4105CSH	Transporter
E3Z27_RS27960	ENOG4105NAU	thioesterase Superfamily protein
E3Z27_RS27980	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E3Z27_RS27985	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E3Z27_RS27990	ENOG4107YNJ	LysR family Transcriptional regulator
E3Z27_RS27995	ENOG4108IJ0	Aspartate ammonia-lyase
E3Z27_RS28005	ENOG4105HDK	L-asparaginase
E3Z27_RS28010	ENOG4108ZX5	transcriptional regulator
E3Z27_RS28020	ENOG41067B5	Histone deacetylase superfamily protein
E3Z27_RS28070	ENOG4105EAB	amino acid AbC transporter
E3Z27_RS28075	ENOG4105E5Q	amino acid AbC transporter
E3Z27_RS28085	ENOG4107QSA	Oxaloacetate decarboxylase
E3Z27_RS28090	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3Z27_RS28095	ENOG4105DUM	transcriptional regulator, lysR family
E3Z27_RS28105	ENOG4106KNT	transcriptional regulator
E3Z27_RS28110	ENOG4105BZU	Histidine kinase
E3Z27_RS28115	ENOG4105C4R	Atp-dependent dna helicase
E3Z27_RS28130	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3Z27_RS28140	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
E3Z27_RS28150	ENOG4105CKI	cobalamin synthesis protein
E3Z27_RS28175	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
E3Z27_RS28185	ENOG4105CC5	ABC transporter
E3Z27_RS28190	ENOG4105DSE	periplasmic solute binding protein
E3Z27_RS28195	ENOG41060X7	Protein of unknown function (DUF3617)
E3Z27_RS28200	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E3Z27_RS28205	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E3Z27_RS28245	ENOG4105HEI	LysR family (Transcriptional regulator
E3Z27_RS28260	ENOG4107VIJ	nudix hydrolase
E3Z27_RS28265	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
E3Z27_RS28270	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E3Z27_RS28275	ENOG4108RWI	nicotinamidase
E3Z27_RS28280	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E3Z27_RS28290	ENOG4105C8Q	Methyl-accepting chemotaxis
E3Z27_RS28295	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E3Z27_RS28300	ENOG410804X	Transcriptional regulator
E3Z27_RS28305	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E3Z27_RS28310	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E3Z27_RS28315	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E3Z27_RS28320	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E3Z27_RS28325	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E3Z27_RS28330	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3Z27_RS28335	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3Z27_RS28345	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E3Z27_RS28350	ENOG41064MJ	ATP synthase, subunit I
E3Z27_RS28355	ENOG4105FA0	parb-like partition protein
E3Z27_RS28360	ENOG4107QJE	Chromosome Partitioning Protein
E3Z27_RS28365	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E3Z27_RS28370	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E3Z27_RS28375	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E3Z27_RS28380	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E3Z27_RS28385	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E3Z27_RS28390	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)